HUMAN|HGNC=384|UniProtKB=Q04828 Q04828 AKR1C1 PTHR11732:SF153 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER C1-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;steroid binding#GO:0005496;lipid binding#GO:0008289;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;secondary metabolic process#GO:0019748;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid derivative metabolic process#GO:1901568;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;steroid metabolic process#GO:0008202;fatty acid metabolic process#GO:0006631;organic cyclic compound metabolic process#GO:1901360;unsaturated fatty acid metabolic process#GO:0033559;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=11018|UniProtKB=Q9H598 Q9H598 SLC32A1 PTHR48017:SF91 OS05G0424000 PROTEIN-RELATED VESICULAR INHIBITORY AMINO ACID TRANSPORTER solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;proton transmembrane transporter activity#GO:0015078;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;neurotransmitter transport#GO:0006836;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;transport vesicle membrane#GO:0030658;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=27301|UniProtKB=Q53ET0 Q53ET0 CRTC2 PTHR13589:SF6 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 2 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 HUMAN|HGNC=6374|UniProtKB=P26715 P26715 KLRC1 PTHR22800:SF242 C-TYPE LECTIN PROTEINS NKG2-A/NKG2-B TYPE II INTEGRAL MEMBRANE PROTEIN HUMAN|HGNC=3526|UniProtKB=Q92800 Q92800 EZH1 PTHR45747:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) HISTONE-LYSINE N-METHYLTRANSFERASE EZH1 histone modifying enzyme#PC00261 HUMAN|HGNC=25952|UniProtKB=Q9NXS2 Q9NXS2 QPCTL PTHR12283:SF3 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-LIKE PROTEIN cation binding#GO:0043169;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=13267|UniProtKB=O95424 O95424 DEXI PTHR17070:SF0 DEXAMETHASONE-INDUCED PROTEIN DEXAMETHASONE-INDUCED PROTEIN HUMAN|HGNC=6175|UniProtKB=Q9NQX7 Q9NQX7 ITM2C PTHR10962:SF5 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2C amyloid-beta binding#GO:0001540;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 glycoprotein biosynthetic process#GO:0009101;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;carbohydrate derivative metabolic process#GO:1901135;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;carbohydrate derivative biosynthetic process#GO:1901137;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=26945|UniProtKB=Q9UDX5 Q9UDX5 MTFP1 PTHR11001:SF2 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrial fission#GO:0000266 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=1709|UniProtKB=P21926 P21926 CD9 PTHR19282:SF163 TETRASPANIN CD9 ANTIGEN intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=9057|UniProtKB=Q96C90 Q96C90 PPP1R14B PTHR16188:SF5 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14B hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096;protein phosphatase inhibitor activity#GO:0004864 response to external biotic stimulus#GO:0043207;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;immune response#GO:0006955;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;defense response#GO:0006952 phosphatase modulator#PC00184 HUMAN|HGNC=25822|UniProtKB=Q9H8K7 Q9H8K7 PAAT PTHR14787:SF3 C10ORF188 FAMILY MEMBER ATPASE PAAT HUMAN|HGNC=10003|UniProtKB=P49802 P49802 RGS7 PTHR45746:SF7 LP21163P REGULATOR OF G-PROTEIN SIGNALING 7 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=6150|UniProtKB=P06756 P06756 ITGAV PTHR23220:SF4 INTEGRIN ALPHA INTEGRIN ALPHA-V integrin#PC00126 CCKR signaling map#P06959>ITGAV#P07133;CCKR signaling map#P06959>ITGAV#G07293;CCKR signaling map#P06959>ITGAV#G06999;Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=24132|UniProtKB=Q96LC9 Q96LC9 BMF PTHR32014:SF2 BCL-2-MODIFYING FACTOR BCL-2-MODIFYING FACTOR negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;positive regulation of programmed cell death#GO:0043068;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;programmed cell death#GO:0012501;regulation of cellular catabolic process#GO:0031329;negative regulation of autophagy#GO:0010507;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;autophagy#GO:0006914;positive regulation of cell death#GO:0010942;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=20644|UniProtKB=Q8TED4 Q8TED4 SLC37A2 PTHR43184:SF9 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A2 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;anion:anion antiporter activity#GO:0015301;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;organophosphate ester transmembrane transporter activity#GO:0015605;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;anion transport#GO:0006820;carbohydrate derivative transport#GO:1901264;inorganic anion transport#GO:0015698 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=11503|UniProtKB=O43426 O43426 SYNJ1 PTHR11200:SF158 INOSITOL 5-PHOSPHATASE SYNAPTOJANIN-1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;head development#GO:0060322;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;animal organ development#GO:0048513;transport#GO:0006810;developmental process#GO:0032502;brain development#GO:0007420;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;glycerolipid metabolic process#GO:0046486;membrane invagination#GO:0010324;establishment of localization#GO:0051234;catabolic process#GO:0009056;vesicle organization#GO:0016050;central nervous system development#GO:0007417;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;phospholipid dephosphorylation#GO:0046839;endocytosis#GO:0006897;multicellular organism development#GO:0007275;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;small molecule catabolic process#GO:0044282;vesicle budding from membrane#GO:0006900;cellular carbohydrate metabolic process#GO:0044262;organelle organization#GO:0006996;anatomical structure development#GO:0048856;dephosphorylation#GO:0016311;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;vesicle-mediated transport in synapse#GO:0099003;small molecule metabolic process#GO:0044281 cell junction#GO:0030054;cytoplasm#GO:0005737;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular#GO:0005622 phosphatase#PC00181 Huntington disease#P00029>Synaptojanin#P00804 HUMAN|HGNC=7659|UniProtKB=P52298 P52298 NCBP2 PTHR18847:SF6 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152 protein-containing complex#GO:0032991;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=30497|UniProtKB=Q2M1P5 Q2M1P5 KIF7 PTHR24115:SF445 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF7 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=30022|UniProtKB=Q86YN6 Q86YN6 PPARGC1B PTHR15528:SF12 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-BETA transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;molecular function regulator#GO:0098772;nuclear receptor transcription coactivator activity#GO:0030374;transcription factor binding#GO:0008134 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=17985|UniProtKB=Q8WZ75 Q8WZ75 ROBO4 PTHR10075:SF56 BASIGIN RELATED ROUNDABOUT HOMOLOG 4 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=30650|UniProtKB=Q9BX79 Q9BX79 STRA6 PTHR21444:SF16 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 RECEPTOR FOR RETINOL UPTAKE STRA6 vitamin transmembrane transport#GO:0035461;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;lipid transport#GO:0006869;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825;lipid localization#GO:0010876 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=8687|UniProtKB=Q9Y5E7 Q9Y5E7 PCDHB2 PTHR24028:SF281 CADHERIN-87A PROTOCADHERIN BETA-2 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=7102|UniProtKB=Q9UNW1 Q9UNW1 MINPP1 PTHR20963:SF8 MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 phosphatase#PC00181 HUMAN|HGNC=24887|UniProtKB=P41247 P41247 PNPLA4 PTHR12406:SF7 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 4 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;chemical homeostasis#GO:0048878;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 phospholipase#PC00186 HUMAN|HGNC=13995|UniProtKB=Q9NQV6 Q9NQV6 PRDM10 PTHR24403:SF48 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 10 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29464|UniProtKB=Q5T751 Q5T751 LCE1C PTHR23263:SF129 SMALL PROLINE-RICH PROTEIN LATE CORNIFIED ENVELOPE PROTEIN 1C HUMAN|HGNC=2537|UniProtKB=P07711 P07711 CTSL PTHR12411:SF57 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L1 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=11924|UniProtKB=Q07011 Q07011 TNFRSF9 PTHR47139:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell population proliferation#GO:0008283;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=8674|UniProtKB=Q9Y5H6 Q9Y5H6 PCDHA8 PTHR24028:SF305 CADHERIN-87A PROTOCADHERIN ALPHA-6-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=23663|UniProtKB=Q9BQB6 Q9BQB6 VKORC1 PTHR14519:SF0 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176 HUMAN|HGNC=17291|UniProtKB=Q13445 Q13445 TMED1 PTHR22811:SF40 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 1 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=10260|UniProtKB=P51449 P51449 RORC PTHR45805:SF1 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C4 zinc finger nuclear receptor#PC00169 Hypoxia response via HIF activation#P00030>TOR#P00817 HUMAN|HGNC=12034|UniProtKB=Q9BUZ4 Q9BUZ4 TRAF4 PTHR10131:SF144 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 4 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 regulation of MAPK cascade#GO:0043408;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;positive regulation of protein modification process#GO:0031401;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;stress-activated MAPK cascade#GO:0051403;cellular protein metabolic process#GO:0044267;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of DNA-binding transcription factor activity#GO:0051091;positive regulation of protein metabolic process#GO:0051247;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;transcription, DNA-templated#GO:0006351;regulation of JNK cascade#GO:0046328;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;JNK cascade#GO:0007254;positive regulation of signaling#GO:0023056;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;tumor necrosis factor-mediated signaling pathway#GO:0033209;RNA biosynthetic process#GO:0032774;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of stress-activated MAPK cascade#GO:0032874;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of stress-activated protein kinase signaling cascade#GO:0070302;cellular macromolecule biosynthetic process#GO:0034645;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of stress-activated MAPK cascade#GO:0032872;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;protein K63-linked ubiquitination#GO:0070534 membrane protein complex#GO:0098796;receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=1819|UniProtKB=Q14002 Q14002 CEACAM7 PTHR12080:SF58 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 7 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=22401|UniProtKB=Q7L273 Q7L273 KCTD9 PTHR14136:SF38 UNCHARACTERIZED BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD9 HUMAN|HGNC=20213|UniProtKB=Q9P0S2 Q9P0S2 COX16 PTHR17130:SF14 MITOCHONDRIAL OUTER MEMBRANE PROTEIN 25 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX16 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=4709|UniProtKB=P10144 P10144 GZMB PTHR24271:SF81 KALLIKREIN-RELATED GRANZYME B serine protease#PC00203 Apoptosis signaling pathway#P00006>Granzyme B#P00265 HUMAN|HGNC=18957|UniProtKB=Q86UL8 Q86UL8 MAGI2 PTHR10316:SF27 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 2 SMAD binding#GO:0046332;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor serine/threonine kinase binding#GO:0033612;G protein-coupled receptor binding#GO:0001664 cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;regulation of biological process#GO:0050789;localization#GO:0051179;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;receptor clustering#GO:0043113;signaling#GO:0023052 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;intracellular#GO:0005622;dendrite#GO:0030425;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=25624|UniProtKB=Q8N5T2 Q8N5T2 TBC1D19 PTHR16110:SF1 TBC1 DOMAIN FAMILY MEMBER 19 TBC1 DOMAIN FAMILY MEMBER 19 HUMAN|HGNC=35155|UniProtKB=Q7Z2Q7 Q7Z2Q7 LRRC70 PTHR45617:SF121 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 70 HUMAN|HGNC=5174|UniProtKB=Q7Z444 Q7Z444 ERAS PTHR24070:SF369 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE ERAS GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=25358|UniProtKB=Q96K19 Q96K19 RNF170 PTHR22894:SF1 UNCHARACTERIZED E3 UBIQUITIN-PROTEIN LIGASE RNF170 HUMAN|HGNC=2036|UniProtKB=P56746 P56746 CLDN15 PTHR12002:SF74 CLAUDIN CLAUDIN-15 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=7047|UniProtKB=Q9UM21 Q9UM21 MGAT4A PTHR12062:SF4 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=16610|UniProtKB=O14633 O14633 LCE2B PTHR23263:SF132 SMALL PROLINE-RICH PROTEIN LATE CORNIFIED ENVELOPE PROTEIN 2A-RELATED HUMAN|HGNC=32483|UniProtKB=P0C6T2 P0C6T2 OST4 PTHR48164:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 protein modifying enzyme#PC00260 HUMAN|HGNC=16155|UniProtKB=Q9BR11 Q9BR11 ZSWIM1 PTHR31569:SF0 SWIM-TYPE DOMAIN-CONTAINING PROTEIN ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 1 HUMAN|Ensembl=ENSG00000283599|UniProtKB=A0A1B0GWI6 A0A1B0GWI6 LOC101059915 PTHR31866:SF3 GENE 4779-RELATED SUBFAMILY NOT NAMED HUMAN|HGNC=9072|UniProtKB=Q02325 Q02325 PLGLB2 PTHR24261:SF13 PLASMINOGEN-RELATED PLASMINOGEN-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 Blood coagulation#P00011>Plasmin#P00415;Blood coagulation#P00011>Plasminogen#P00408;Plasminogen activating cascade#P00050>Plasminogen#P01255;Plasminogen activating cascade#P00050>Plasmin#P01246 HUMAN|HGNC=18925|UniProtKB=Q3SY46 Q3SY46 KRTAP13-3 PTHR19051:SF28 KERATIN-ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 13-3 structural protein#PC00211 HUMAN|HGNC=10889|UniProtKB=O95343 O95343 SIX3 PTHR10390:SF31 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;brain development#GO:0007420;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;sensory system development#GO:0048880;visual system development#GO:0150063;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;eye development#GO:0001654;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;sensory organ development#GO:0007423;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 HUMAN|HGNC=32934|UniProtKB=G3V0H7 G3V0H7 SLCO1B7 PTHR11388:SF154 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B7-RELATED secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=19962|UniProtKB=Q6ZNE5 Q6ZNE5 ATG14 PTHR13664:SF0 BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;positive regulation of cellular metabolic process#GO:0031325;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;positive regulation of biological process#GO:0048518;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;organophosphate metabolic process#GO:0019637;regulation of lipid metabolic process#GO:0019216;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;phosphatidylinositol phosphorylation#GO:0046854;regulation of cellular metabolic process#GO:0031323;lipid metabolic process#GO:0006629;regulation of phosphate metabolic process#GO:0019220;positive regulation of molecular function#GO:0044093;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;process utilizing autophagic mechanism#GO:0061919;positive regulation of transferase activity#GO:0051347;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;glycerolipid metabolic process#GO:0046486;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;phosphatidylinositol metabolic process#GO:0046488;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;regulation of primary metabolic process#GO:0080090;organelle assembly#GO:0070925;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;positive regulation of kinase activity#GO:0033674;cellular lipid metabolic process#GO:0044255;regulation of transferase activity#GO:0051338 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;membrane#GO:0016020;phosphatidylinositol 3-kinase complex, class III#GO:0035032;intracellular organelle#GO:0043229;autophagosome#GO:0005776;mitochondria-associated endoplasmic reticulum membrane#GO:0044233;whole membrane#GO:0098805;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=21303|UniProtKB=Q8NDY3 Q8NDY3 ADPRHL1 PTHR16222:SF23 ADP-RIBOSYLGLYCOHYDROLASE [PROTEIN ADP-RIBOSYLARGININE] HYDROLASE-LIKE PROTEIN 1 hydrolase#PC00121 HUMAN|HGNC=15025|UniProtKB=Q8NGZ2 Q8NGZ2 OR14K1 PTHR26452:SF388 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14K1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=18942|UniProtKB=Q3SYF9 Q3SYF9 KRTAP19-7 PTHR38140:SF7 KERATIN-ASSOCIATED PROTEIN 19-3-RELATED KERATIN-ASSOCIATED PROTEIN 19-7 HUMAN|HGNC=29121|UniProtKB=Q9Y4B5 Q9Y4B5 MTCL1 PTHR15742:SF3 UNCHARACTERIZED MICROTUBULE CROSS-LINKING FACTOR 1 HUMAN|HGNC=17796|UniProtKB=Q9C0E2 Q9C0E2 XPO4 PTHR12596:SF1 EXPORTIN 4,7-RELATED EXPORTIN-4 transporter activity#GO:0005215 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;nuclear transport#GO:0051169 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=20456|UniProtKB=Q6Q0C0 Q6Q0C0 TRAF7 PTHR19848:SF6 WD40 REPEAT PROTEIN E3 UBIQUITIN-PROTEIN LIGASE TRAF7 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;biological regulation#GO:0065007;ribosome biogenesis#GO:0042254;signaling#GO:0023052;protein-containing complex subunit organization#GO:0043933;Notch signaling pathway#GO:0007219 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=19010|UniProtKB=Q8IZF4 Q8IZF4 ADGRG5 PTHR12011:SF326 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=3791|UniProtKB=P15328 P15328 FOLR1 PTHR10517:SF15 FOLATE RECEPTOR FOLATE RECEPTOR ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell recognition#GO:0008037;plasma membrane fusion#GO:0045026;fertilization#GO:0009566;membrane organization#GO:0061024;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;biological adhesion#GO:0022610;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;multi-organism process#GO:0051704;cell-cell recognition#GO:0009988;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;membrane fusion#GO:0061025;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;multi-organism reproductive process#GO:0044703 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;anchored component of plasma membrane#GO:0046658;intrinsic component of membrane#GO:0031224;intrinsic component of plasma membrane#GO:0031226;anchored component of membrane#GO:0031225;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=2333|UniProtKB=Q66K79 Q66K79 CPZ PTHR11532:SF63 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE Z hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190 HUMAN|HGNC=13854|UniProtKB=Q969J2 Q969J2 ZKSCAN4 PTHR23226:SF67 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23764|UniProtKB=Q6UWV6 Q6UWV6 ENPP7 PTHR10151:SF63 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 7 HUMAN|HGNC=26993|UniProtKB=Q19AV6 Q19AV6 ZSWIM7 PTHR28498:SF1 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=10619|UniProtKB=P78556 P78556 CCL20 PTHR12015:SF108 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 20 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=29347|UniProtKB=Q96M94 Q96M94 KLHL15 PTHR45632:SF12 LD33804P KELCH-LIKE PROTEIN 15 HUMAN|HGNC=7968|UniProtKB=O75469 O75469 NR1I2 PTHR24082:SF39 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 Angiogenesis#P00005>PAR#P00192 HUMAN|HGNC=18651|UniProtKB=Q7Z7M1 Q7Z7M1 ADGRD2 PTHR12011:SF58 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR D2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=24362|UniProtKB=C4AMC7 C4AMC7 WASH3P PTHR23331:SF2 CXYORF1 WAS PROTEIN FAMILY HOMOLOG 2-RELATED HUMAN|HGNC=10634|UniProtKB=P80098 P80098 CCL7 PTHR12015:SF161 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 7 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=16875|UniProtKB=Q9UBG0 Q9UBG0 MRC2 PTHR22803:SF69 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED C-TYPE MANNOSE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 HUMAN|HGNC=24472|UniProtKB=Q6PGN9 Q6PGN9 PSRC1 PTHR21584:SF1 DIFFERENTIAL DISPLAY AND ACTIVATED BY P53 DDA3 /G2 S PHASE EXPRESSED 1 PROLINE/SERINE-RICH COILED-COIL PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 nuclear chromosome segregation#GO:0098813;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of chromosome localization#GO:0051303;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;metaphase plate congression#GO:0051310;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;mitotic metaphase plate congression#GO:0007080;mitotic sister chromatid segregation#GO:0000070;chromosome localization#GO:0050000;establishment of organelle localization#GO:0051656 supramolecular complex#GO:0099080;spindle pole#GO:0000922;spindle microtubule#GO:0005876;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 HUMAN|HGNC=23427|UniProtKB=Q8N8K9 Q8N8K9 KIAA1958 PTHR46963:SF1 SIMILAR TO RIKEN CDNA E130308A19 DUF3504 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=30705|UniProtKB=Q8NHS9 Q8NHS9 SPATA22 PTHR35258:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 22 SPERMATOGENESIS-ASSOCIATED PROTEIN 22 meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794;meiotic cell cycle process#GO:1903046;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;reproductive process#GO:0022414;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049 HUMAN|HGNC=3231|UniProtKB=Q9HCU4 Q9HCU4 CELSR2 PTHR24026:SF32 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 2 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=17346|UniProtKB=Q13523 Q13523 PRPF4B PTHR24056:SF45 CELL DIVISION PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE PRP4 HOMOLOG cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=16446|UniProtKB=Q9BXL6 Q9BXL6 CARD14 PTHR14559:SF1 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 14 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=7400|UniProtKB=P80294 P80294 MT1H PTHR23299:SF4 METALLOTHIONEIN METALLOTHIONEIN-1H cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;transition metal ion homeostasis#GO:0055076;response to metal ion#GO:0010038;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;response to toxic substance#GO:0009636;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=30718|UniProtKB=P59910 P59910 DNAJB13 PTHR24078:SF519 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 13 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488;chaperone binding#GO:0051087 'de novo' protein folding#GO:0006458;cellular process#GO:0009987;chaperone-mediated protein folding#GO:0061077;protein folding#GO:0006457 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=24797|UniProtKB=Q6ZRV2 Q6ZRV2 FAM83H PTHR16181:SF22 UNCHARACTERIZED PROTEIN FAM83H protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;cellular protein localization#GO:0034613;regulation of localization#GO:0032879;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;positive regulation of cell motility#GO:2000147;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;positive regulation of biological process#GO:0048518;intermediate filament cytoskeleton organization#GO:0045104;regulation of cellular component movement#GO:0051270;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell motility#GO:0048870;cellular process#GO:0009987;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;cellular component organization or biogenesis#GO:0071840;positive regulation of cell migration#GO:0030335;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intracellular#GO:0005622;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 HUMAN|HGNC=15201|UniProtKB=Q9H344 Q9H344 OR51I2 PTHR26450:SF112 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51I2 transmembrane signal receptor#PC00197 HUMAN|HGNC=2950|UniProtKB=Q8TE73 Q8TE73 DNAH5 PTHR10676:SF344 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN 5, AXONEMAL pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=24870|UniProtKB=Q68CQ7 Q68CQ7 GLT8D1 PTHR13778:SF3 GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=16810|UniProtKB=P57771 P57771 RGS8 PTHR10845:SF147 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 8 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=7392|UniProtKB=P35548 P35548 MSX2 PTHR24338:SF10 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 multicellular organismal process#GO:0032501;embryo development#GO:0009790;anatomical structure morphogenesis#GO:0009653;embryonic morphogenesis#GO:0048598;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 HUMAN|HGNC=6133|UniProtKB=O14498 O14498 ISLR PTHR24366:SF14 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IMMUNOGLOBULIN SUPERFAMILY CONTAINING LEUCINE-RICH REPEAT PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=4173|UniProtKB=P43694 P43694 GATA4 PTHR10071:SF154 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>GATA2/4#P06859 HUMAN|HGNC=6376|UniProtKB=Q07444 Q07444 KLRC3 PTHR22800:SF239 C-TYPE LECTIN PROTEINS NKG2-E TYPE II INTEGRAL MEMBRANE PROTEIN HUMAN|HGNC=5591|UniProtKB=P01768 P01768 IGHV3-30 PTHR23266:SF241 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=8059|UniProtKB=Q14980 Q14980 NUMA1 PTHR18902:SF24 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED NUCLEAR MITOTIC APPARATUS PROTEIN 1 endosomal transport#GO:0016197;cellular localization#GO:0051641;organelle localization#GO:0051640;protein targeting to vacuole#GO:0006623;nuclear division#GO:0000280;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;regulation of protein localization#GO:0032880;establishment of protein localization to vacuole#GO:0072666;Golgi organization#GO:0007030;protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;cellular component organization#GO:0016043;regulation of cellular localization#GO:0060341;peptide transport#GO:0015833;microtubule organizing center organization#GO:0031023;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle orientation#GO:0000132;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein transport#GO:0015031;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087;establishment or maintenance of cell polarity#GO:0007163;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;establishment of spindle orientation#GO:0051294;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;microtubule cytoskeleton organization involved in mitosis#GO:1902850;protein targeting to lysosome#GO:0006622;mitotic cell cycle process#GO:1903047;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;mitotic nuclear division#GO:0140014;protein localization to organelle#GO:0033365;regulation of protein transport#GO:0051223;spindle localization#GO:0051653;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;establishment of protein localization to organelle#GO:0072594;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;establishment of spindle localization#GO:0051293;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;establishment of mitotic spindle localization#GO:0040001;microtubule-based process#GO:0007017;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular protein transport#GO:0006886 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;spindle#GO:0005819;microtubule#GO:0005874;membrane-enclosed lumen#GO:0031974;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;organelle lumen#GO:0043233;spindle microtubule#GO:0005876;nucleus#GO:0005634;nucleoplasm#GO:0005654;Golgi apparatus#GO:0005794;intracellular organelle lumen#GO:0070013;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;centriole#GO:0005814;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=19401|UniProtKB=Q96DM1 Q96DM1 PGBD4 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 HUMAN|HGNC=9023|UniProtKB=Q13835 Q13835 PKP1 PTHR10372:SF3 PLAKOPHILLIN-RELATED PLAKOPHILIN-1 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cell junction organization#GO:0034330;cytoskeleton organization#GO:0007010;cell junction assembly#GO:0034329;intermediate filament cytoskeleton organization#GO:0045104 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130 HUMAN|HGNC=16878|UniProtKB=P42694 P42694 HELZ PTHR10887:SF365 DNA2/NAM7 HELICASE FAMILY HELICASE WITH ZINC FINGER DOMAIN-RELATED posttranscriptional regulation of gene expression#GO:0010608;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;negative regulation of metabolic process#GO:0009892;gene silencing by RNA#GO:0031047;cellular process#GO:0009987;post-transcriptional gene silencing by RNA#GO:0035194;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;posttranscriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;gene silencing#GO:0016458;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;regulation of gene expression, epigenetic#GO:0040029;metabolic process#GO:0008152 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=28954|UniProtKB=Q96BP3 Q96BP3 PPWD1 PTHR45625:SF5 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 chaperone#PC00072 HUMAN|HGNC=9485|UniProtKB=Q9Y6M0 Q9Y6M0 PRSS21 PTHR24256:SF173 TRYPTASE-RELATED TESTISIN serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=28480|UniProtKB=Q8TBE7 Q8TBE7 SLC35G2 PTHR22911:SF52 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G2 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=13787|UniProtKB=Q9HB09 Q9HB09 BCL2L12 PTHR14965:SF2 SI:CH73-248E21.1 BCL-2-LIKE PROTEIN 12 HUMAN|HGNC=20305|UniProtKB=Q8N130 Q8N130 SLC34A3 PTHR10010:SF35 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2C secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;solute:cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;inorganic anion transport#GO:0015698 microvillus#GO:0005902;supramolecular complex#GO:0099080;brush border#GO:0005903;actin filament bundle#GO:0032432;cluster of actin-based cell projections#GO:0098862;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=29467|UniProtKB=Q5T754 Q5T754 LCE1F PTHR23263:SF141 SMALL PROLINE-RICH PROTEIN LATE CORNIFIED ENVELOPE PROTEIN 1F HUMAN|HGNC=3243|UniProtKB=Q9NZN4 Q9NZN4 EHD2 PTHR11216:SF62 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 2 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 microtubule-based protein transport#GO:0099118;endosomal transport#GO:0016197;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;endocytic recycling#GO:0032456;membrane invagination#GO:0010324;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;protein localization to plasma membrane#GO:0072659;vesicle localization#GO:0051648;protein localization to membrane#GO:0072657;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;protein localization to cell periphery#GO:1990778;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;perinuclear region of cytoplasm#GO:0048471;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=10683|UniProtKB=O14521 O14521 SDHD PTHR13337:SF6 SUCCINATE DEHYDROGENASE SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;tricarboxylic acid cycle#GO:0006099;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;metabolic process#GO:0008152;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respiratory chain complex II#GO:0045273;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 HUMAN|HGNC=658|UniProtKB=P84085 P84085 ARF5 PTHR11711:SF323 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 5 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 HUMAN|HGNC=29130|UniProtKB=O94927 O94927 HAUS5 PTHR28588:SF1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 5 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 5 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=30545|UniProtKB=Q96HQ2 Q96HQ2 CDKN2AIPNL PTHR16148:SF11 NF-KAPPA-B-REPRESSING FACTOR-RELATED CDKN2A-INTERACTING PROTEIN-RELATED membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=16998|UniProtKB=P49755 P49755 TMED10 PTHR22811:SF183 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 10 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=26604|UniProtKB=Q8IW93 Q8IW93 ARHGEF19 PTHR12845:SF6 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 19 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;regulation of organelle organization#GO:0033043;positive regulation of molecular function#GO:0044093;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=14042|UniProtKB=Q9Y3B7 Q9Y3B7 MRPL11 PTHR11661:SF19 60S RIBOSOMAL PROTEIN L12 39S RIBOSOMAL PROTEIN L11, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=20663|UniProtKB=Q6KCM7 Q6KCM7 SLC25A25 PTHR24089:SF57 SOLUTE CARRIER FAMILY 25 CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN SCAMC-2 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ATP transmembrane transporter activity#GO:0005347;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;ion transmembrane transporter activity#GO:0015075;nucleotide transmembrane transporter activity#GO:0015215;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 mitochondrial carrier protein#PC00158 HUMAN|HGNC=26897|UniProtKB=Q8NEM1 Q8NEM1 ZNF680 PTHR24384:SF121 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 680 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=15453|UniProtKB=Q9H3P7 Q9H3P7 ACBD3 PTHR22973:SF11 LD35087P GOLGI RESIDENT PROTEIN GCP60 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=15764|UniProtKB=Q9GZN2 Q9GZN2 TGIF2 PTHR11850:SF68 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=27013|UniProtKB=Q86V40 Q86V40 TRABD2A PTHR31120:SF7 METALLOPROTEASE TIKI METALLOPROTEASE TIKI1 metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;Wnt-protein binding#GO:0017147;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;Wnt signaling pathway#GO:0016055 intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;intrinsic component of plasma membrane#GO:0031226;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886;integral component of organelle membrane#GO:0031301 metalloprotease#PC00153 HUMAN|HGNC=13879|UniProtKB=Q8N1T3 Q8N1T3 MYO1H PTHR13140:SF353 MYOSIN UNCONVENTIONAL MYOSIN-IH pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 microvillus#GO:0005902;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin binding motor protein#PC00040 HUMAN|HGNC=18291|UniProtKB=Q9NPF5 Q9NPF5 DMAP1 PTHR12855:SF10 DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;histone exchange#GO:0043486;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone H4 acetylation#GO:0043967;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;peptidyl-lysine acetylation#GO:0018394;nucleosome organization#GO:0034728;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=8038|UniProtKB=P30990 P30990 NTS PTHR15356:SF0 NEUROTENSIN/NEUROMEDIN N NEUROTENSIN/NEUROMEDIN N HUMAN|HGNC=167|UniProtKB=P61163 P61163 ACTR1A PTHR11937:SF370 ACTIN ALPHA-CENTRACTIN actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 HUMAN|HGNC=25065|UniProtKB=Q7Z4M0 Q7Z4M0 REC114 PTHR34921:SF1 MEIOTIC RECOMBINATION PROTEIN REC114 MEIOTIC RECOMBINATION PROTEIN REC114 HUMAN|HGNC=28221|UniProtKB=Q96S82 Q96S82 UBL7 PTHR10677:SF25 UBIQUILIN UBIQUITIN-LIKE PROTEIN 7 protein binding#GO:0005515;binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=24876|UniProtKB=Q7Z5G4 Q7Z5G4 GOLGA7 PTHR13254:SF1 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 GOLGIN SUBFAMILY A MEMBER 7 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to plasma membrane#GO:0072659;cellular macromolecule biosynthetic process#GO:0034645;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein localization to cell periphery#GO:1990778;Golgi to plasma membrane protein transport#GO:0043001;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=22992|UniProtKB=Q96LD8 Q96LD8 SENP8 PTHR46468:SF1 SENTRIN-SPECIFIC PROTEASE 8 SENTRIN-SPECIFIC PROTEASE 8 protease#PC00190 HUMAN|HGNC=18364|UniProtKB=Q8IZJ0 Q8IZJ0 IFNL2 PTHR31943:SF1 INTERLEUKIN-28 AND 29 INTERFERON LAMBDA-2-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;immune response#GO:0006955;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 interleukin superfamily#PC00128 HUMAN|HGNC=8063|UniProtKB=O75694 O75694 NUP155 PTHR10350:SF6 NUCLEAR PORE COMPLEX PROTEIN NUP155 NUCLEAR PORE COMPLEX PROTEIN NUP155 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;protein localization to membrane#GO:0072657;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;chromosome organization#GO:0051276;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=23745|UniProtKB=Q5JTN6 Q5JTN6 WDR38 PTHR22847:SF626 WD40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 38 HUMAN|HGNC=15195|UniProtKB=Q9H255 Q9H255 OR51E2 PTHR26450:SF92 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51E2 transmembrane signal receptor#PC00197 HUMAN|HGNC=8754|UniProtKB=P49585 P49585 PCYT1A PTHR10739:SF19 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE A cation binding#GO:0043169;transferase activity#GO:0016740;phosphatidylcholine binding#GO:0031210;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=28169|UniProtKB=Q96IX9 Q96IX9 ANKRD36BP1 PTHR24147:SF50 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 36A-RELATED HUMAN|HGNC=1645|UniProtKB=P25063 P25063 CD24 PTHR16676:SF0 SIGNAL TRANSDUCER CD24 SIGNAL TRANSDUCER CD24 HUMAN|HGNC=15583|UniProtKB=Q6UWM7 Q6UWM7 LCTL PTHR10353:SF258 GLYCOSYL HYDROLASE LACTASE-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110 HUMAN|HGNC=23512|UniProtKB=Q7Z5L2 Q7Z5L2 R3HCC1L PTHR21678:SF7 GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88 COILED-COIL DOMAIN-CONTAINING PROTEIN R3HCC1L protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|Gene=YG024_HUMAN|UniProtKB=Q6ZRM9 Q6ZRM9 - PTHR37553:SF6 FAMILY NOT NAMED SUBFAMILY NOT NAMED HUMAN|HGNC=15087|UniProtKB=Q8NHA4 Q8NHA4 OR2AE1 PTHR26453:SF196 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AE1 transmembrane signal receptor#PC00197 HUMAN|HGNC=6710|UniProtKB=P09960 P09960 LTA4H PTHR45726:SF3 FAMILY NOT NAMED LEUKOTRIENE A-4 HYDROLASE HUMAN|HGNC=13324|UniProtKB=Q9C086 Q9C086 INO80B PTHR21561:SF12 INO80 COMPLEX SUBUNIT B INO80 COMPLEX SUBUNIT B cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;ATP-dependent chromatin remodeling#GO:0043044;chromatin organization#GO:0006325;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;Ino80 complex#GO:0031011;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 HUMAN|HGNC=3604|UniProtKB=P35556 P35556 FBN2 PTHR24039:SF26 FIBRILLIN-RELATED FIBRILLIN-2 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=21725|UniProtKB=Q7Z4T8 Q7Z4T8 GALNTL5 PTHR11675:SF17 N-ACETYLGALACTOSAMINYLTRANSFERASE INACTIVE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE-LIKE PROTEIN 5 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 male gamete generation#GO:0048232;signal transduction#GO:0007165;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;regulation of signaling#GO:0023051;spermatid differentiation#GO:0048515;regulation of Notch signaling pathway#GO:0008593;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of signal transduction#GO:0009966;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multi-organism reproductive process#GO:0044703;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;cell communication#GO:0007154;cellular process#GO:0009987;multi-organism process#GO:0051704;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;regulation of response to stimulus#GO:0048583;spermatid development#GO:0007286;response to stimulus#GO:0050896;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;Notch signaling pathway#GO:0007219 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=15103|UniProtKB=Q8NGS7 Q8NGS7 OR13C8 PTHR26453:SF87 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C8 transmembrane signal receptor#PC00197 HUMAN|HGNC=1515|UniProtKB=P20810 P20810 CAST PTHR10077:SF0 CALPASTATIN CALPASTATIN cysteine-type peptidase activity#GO:0008234;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;cysteine-type endopeptidase inhibitor activity#GO:0004869;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of catalytic activity#GO:0050790;protein processing#GO:0016485;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease inhibitor#PC00191 HUMAN|HGNC=14048|UniProtKB=Q9Y3D3 Q9Y3D3 MRPS16 PTHR12919:SF27 30S RIBOSOMAL PROTEIN S16 28S RIBOSOMAL PROTEIN S16, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 HUMAN|HGNC=20583|UniProtKB=Q86W10 Q86W10 CYP4Z1 PTHR24291:SF39 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4A11-RELATED oxygenase#PC00177 HUMAN|HGNC=16916|UniProtKB=Q8IUN9 Q8IUN9 CLEC10A PTHR22802:SF416 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 10 MEMBER A membrane traffic protein#PC00150 HUMAN|HGNC=3675|UniProtKB=O95750 O95750 FGF19 PTHR11486:SF74 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 19 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 HUMAN|HGNC=16896|UniProtKB=Q7Z6M1 Q7Z6M1 RABEPK PTHR46647:SF1 RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS HUMAN|HGNC=32284|UniProtKB=P0CI00 P0CI00 ZNF705B PTHR24381:SF303 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 705A-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=17059|UniProtKB=Q9NTJ5 Q9NTJ5 SACM1L PTHR45662:SF2 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=9217|UniProtKB=P49335 P49335 POU3F4 PTHR11636:SF83 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=24330|UniProtKB=Q7Z7G2 Q7Z7G2 CPLX4 PTHR16705:SF7 COMPLEXIN COMPLEXIN-4 protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;cell junction#GO:0030054;SNARE complex#GO:0031201;terminal bouton#GO:0043195;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=5898|UniProtKB=A0A075B6K2 A0A075B6K2 IGLV3-12 PTHR23267:SF393 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-12 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=21391|UniProtKB=Q9P0V8 Q9P0V8 SLAMF8 PTHR12080:SF92 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 8 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=1744|UniProtKB=Q99741 Q99741 CDC6 PTHR10763:SF26 CELL DIVISION CONTROL PROTEIN 6-RELATED CELL DIVISION CONTROL PROTEIN 6 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;mitotic DNA replication checkpoint#GO:0033314;regulation of biological process#GO:0050789;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;cell cycle checkpoint#GO:0000075;mitotic nuclear division#GO:0140014;negative regulation of cellular process#GO:0048523;mitotic cell cycle checkpoint#GO:0007093;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;mitotic DNA integrity checkpoint#GO:0044774;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;DNA replication checkpoint#GO:0000076;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839 replication origin binding protein#PC00199 HUMAN|HGNC=20576|UniProtKB=Q6UW02 Q6UW02 CYP20A1 PTHR24280:SF4 CYTOCHROME P450 20A1 CYTOCHROME P450 20A1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxygenase#PC00177 HUMAN|HGNC=1033|UniProtKB=P23560 P23560 BDNF PTHR11589:SF3 NERVE GROWTH FACTOR NGF -RELATED BRAIN-DERIVED NEUROTROPHIC FACTOR receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;protein binding#GO:0005515;molecular function regulator#GO:0098772;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 neuron apoptotic process#GO:0051402;regulation of protein metabolic process#GO:0051246;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;negative regulation of neuron death#GO:1901215;nervous system development#GO:0007399;regulation of biological process#GO:0050789;cognition#GO:0050890;positive regulation of cell development#GO:0010720;cellular protein metabolic process#GO:0044267;positive regulation of axonogenesis#GO:0050772;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;positive regulation of neurogenesis#GO:0050769;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;regulation of phosphorylation#GO:0042325;positive regulation of cell growth#GO:0030307;signal transduction#GO:0007165;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of neuron death#GO:1901214;regulation of anatomical structure morphogenesis#GO:0022603;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;behavior#GO:0007610;protein modification process#GO:0036211;growth#GO:0040007;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;neuron differentiation#GO:0030182;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;regulation of programmed cell death#GO:0043067;regulation of anatomical structure size#GO:0090066;positive regulation of protein phosphorylation#GO:0001934;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;nervous system process#GO:0050877;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;positive regulation of protein metabolic process#GO:0051247;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;positive regulation of cellular component organization#GO:0051130;regulation of cell death#GO:0010941;peptidyl-serine modification#GO:0018209;regulation of protein modification process#GO:0031399;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;system process#GO:0003008;positive regulation of cellular metabolic process#GO:0031325;neuron death#GO:0070997;plasma membrane bounded cell projection organization#GO:0120036;regulation of phosphorus metabolic process#GO:0051174;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of growth#GO:0045927;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of axonogenesis#GO:0050770;regulation of cell projection organization#GO:0031344;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;regulation of cell morphogenesis involved in differentiation#GO:0010769;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;positive regulation of cell projection organization#GO:0031346;macromolecule modification#GO:0043412;developmental process#GO:0032502;peptidyl-amino acid modification#GO:0018193;regulation of cell differentiation#GO:0045595;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of neuron differentiation#GO:0045666;developmental growth involved in morphogenesis#GO:0060560;regulation of apoptotic process#GO:0042981;positive regulation of cell differentiation#GO:0045597;developmental growth#GO:0048589;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;cell growth#GO:0016049;positive regulation of developmental process#GO:0051094;negative regulation of apoptotic process#GO:0043066;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;generation of neurons#GO:0048699 neurotrophic factor#PC00163 Huntington disease#P00029>BDNF#G01531;Huntington disease#P00029>BDNF#P00795;Metabotropic glutamate receptor group II pathway#P00040>BDNF#G01540 HUMAN|HGNC=13646|UniProtKB=Q86VI4 Q86VI4 LAPTM4B PTHR12479:SF6 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4B bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 HUMAN|HGNC=19022|UniProtKB=O43301 O43301 HSPA12A PTHR14187:SF46 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12A HUMAN|HGNC=6025|UniProtKB=P10145 P10145 CXCL8 PTHR10179:SF85 CXC CHEMOKINE INTERLEUKIN-8 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856;CCKR signaling map#P06959>IL8#G07001;Interleukin signaling pathway#P00036>Interleukin#P00970;CCKR signaling map#P06959>IL8#G07296;CCKR signaling map#P06959>IL8#P07136 HUMAN|HGNC=15805|UniProtKB=Q96QF7 Q96QF7 GCNA PTHR23099:SF0 TRANSCRIPTIONAL REGULATOR ACIDIC REPEAT-CONTAINING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024 HUMAN|HGNC=32951|UniProtKB=Q5DT21 Q5DT21 SPINK9 PTHR47499:SF2 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 SERINE PROTEASE INHIBITOR KAZAL-TYPE 9 protease inhibitor#PC00191 HUMAN|HGNC=36|UniProtKB=Q8N139 Q8N139 ABCA6 PTHR19229:SF13 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 6 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=941|UniProtKB=Q9UL15 Q9UL15 BAG5 PTHR12329:SF2 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 5 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;chaperone binding#GO:0051087;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 negative regulation of cellular metabolic process#GO:0031324;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;protein stabilization#GO:0050821;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;regulation of protein stability#GO:0031647;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein ubiquitination#GO:0031397;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 HUMAN|HGNC=25832|UniProtKB=A0PJE2 A0PJE2 DHRS12 PTHR44656:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 12 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 12 dehydrogenase#PC00092 HUMAN|HGNC=3763|UniProtKB=P17948 P17948 FLT1 PTHR24416:SF390 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=2624|UniProtKB=A0A087X1C5 A0A087X1C5 CYP2D7 PTHR24300:SF1 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2D6-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=5836|UniProtKB=A0A0C4DH24 A0A0C4DH24 IGKV6-21 PTHR23267:SF459 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 6-21-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=8748|UniProtKB=Q16549 Q16549 PCSK7 PTHR42884:SF28 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 7 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;protein metabolic process#GO:0019538;protein processing#GO:0016485;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 HUMAN|HGNC=24599|UniProtKB=Q9UHY7 Q9UHY7 ENOPH1 PTHR20371:SF3 ENOLASE-PHOSPHATASE E1 ENOLASE-PHOSPHATASE E1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphatase#PC00181 HUMAN|HGNC=27029|UniProtKB=Q6P4H8 Q6P4H8 ATPSCKMT PTHR13610:SF8 UNCHARACTERIZED ATP SYNTHASE SUBUNIT C LYSINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;purine nucleotide biosynthetic process#GO:0006164;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;nucleobase-containing compound metabolic process#GO:0006139;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;ribose phosphate metabolic process#GO:0019693;positive regulation of transmembrane transport#GO:0034764;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;cellular protein metabolic process#GO:0044267;purine nucleotide metabolic process#GO:0006163;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;regulation of ion transmembrane transport#GO:0034765;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;cation transport#GO:0006812;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;protein metabolic process#GO:0019538;heterocycle metabolic process#GO:0046483;peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;transmembrane transport#GO:0055085;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;positive regulation of ion transmembrane transporter activity#GO:0032414;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;mitochondrial transport#GO:0006839;ATP synthesis coupled proton transport#GO:0015986;positive regulation of transporter activity#GO:0032411;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of ion transmembrane transport#GO:0034767;oxidative phosphorylation#GO:0006119;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleoside triphosphate metabolic process#GO:0009199;cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;inorganic cation transmembrane transport#GO:0098662;positive regulation of cellular metabolic process#GO:0031325;inorganic ion transmembrane transport#GO:0098660;nucleotide biosynthetic process#GO:0009165;regulation of phosphorus metabolic process#GO:0051174;protein alkylation#GO:0008213;protein methylation#GO:0006479;establishment of localization#GO:0051234;ATP metabolic process#GO:0046034;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;mitochondrial transmembrane transport#GO:1990542;positive regulation of biological process#GO:0048518;purine nucleoside triphosphate biosynthetic process#GO:0009145;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;positive regulation of transport#GO:0051050;ribonucleoside triphosphate biosynthetic process#GO:0009201;regulation of cellular localization#GO:0060341;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;ribonucleotide biosynthetic process#GO:0009260;macromolecule methylation#GO:0043414;positive regulation of phosphate metabolic process#GO:0045937;regulation of ion transport#GO:0043269;aromatic compound biosynthetic process#GO:0019438;peptidyl-lysine trimethylation#GO:0018023;intracellular transport#GO:0046907;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of ion transport#GO:0043270;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;transport#GO:0006810;peptidyl-amino acid modification#GO:0018193;purine-containing compound biosynthetic process#GO:0072522;cation transmembrane transport#GO:0098655;positive regulation of metabolic process#GO:0009893;regulation of transport#GO:0051049;phosphorylation#GO:0016310;metabolic process#GO:0008152;monovalent inorganic cation transport#GO:0015672;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;methylation#GO:0032259;regulation of cellular biosynthetic process#GO:0031326;biological regulation#GO:0065007;energy coupled proton transport, down electrochemical gradient#GO:0015985;establishment of localization in cell#GO:0051649;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29878|UniProtKB=Q9NQR4 Q9NQR4 NIT2 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase#PC00121 HUMAN|HGNC=24152|UniProtKB=Q96IZ7 Q96IZ7 RSRC1 PTHR31968:SF4 SERINE/ARGININE-RELATED PROTEIN 53 SERINE/ARGININE-RELATED PROTEIN 53 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;alternative mRNA splicing, via spliceosome#GO:0000380;RNA splicing, via transesterification reactions#GO:0000375;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18541|UniProtKB=Q8IZD2 Q8IZD2 KMT2E PTHR46462:SF2 UPSET, ISOFORM A INACTIVE HISTONE-LYSINE N-METHYLTRANSFERASE 2E HUMAN|HGNC=10891|UniProtKB=Q8N196 Q8N196 SIX5 PTHR10390:SF40 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 HUMAN|HGNC=24013|UniProtKB=Q5QJE6 Q5QJE6 DNTTIP2 PTHR21686:SF12 UNCHARACTERIZED DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 HUMAN|HGNC=25851|UniProtKB=Q9BRX5 Q9BRX5 GINS3 PTHR22768:SF0 UNCHARACTERIZED DNA REPLICATION COMPLEX GINS PROTEIN PSF3 HUMAN|HGNC=15035|UniProtKB=Q8NGY6 Q8NGY6 OR6N2 PTHR26451:SF972 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 6N2 HUMAN|HGNC=11736|UniProtKB=Q9BXU2 Q9BXU2 TEX13B PTHR23111:SF64 ZINC FINGER PROTEIN TESTIS-EXPRESSED PROTEIN 13B HUMAN|HGNC=18882|UniProtKB=P59544 P59544 TAS2R50 PTHR11394:SF43 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 50 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=7999|UniProtKB=P56975 P56975 NRG3 PTHR11100:SF18 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-3, MEMBRANE-BOUND ISOFORM receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 HUMAN|HGNC=9963|UniProtKB=Q8NFH8 Q8NFH8 REPS2 PTHR11216:SF64 EH DOMAIN RALBP1-ASSOCIATED EPS DOMAIN-CONTAINING PROTEIN 2 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=28078|UniProtKB=A1A4V9 A1A4V9 CCDC189 PTHR28457:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 HUMAN|HGNC=28020|UniProtKB=Q86TI4 Q86TI4 WDR86 PTHR44489:SF11 FAMILY NOT NAMED WD REPEAT-CONTAINING PROTEIN 86 HUMAN|HGNC=13814|UniProtKB=Q9H427 Q9H427 KCNK15 PTHR11003:SF18 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 15 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=16154|UniProtKB=Q969T3 Q969T3 SNX21 PTHR20939:SF10 SORTING NEXIN 20, 21 SORTING NEXIN-21 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28163|UniProtKB=Q9BUN5 Q9BUN5 CCDC28B PTHR13400:SF2 CHEMOKINE C-C MOTIF RECEPTOR 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 28B transmembrane signal receptor#PC00197 HUMAN|HGNC=15682|UniProtKB=Q8NDX5 Q8NDX5 PHC3 PTHR12247:SF88 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 3 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=5037|UniProtKB=O14979 O14979 HNRNPDL PTHR48033:SF2 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D-LIKE nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=7710|UniProtKB=O75489 O75489 NDUFS3 PTHR10884:SF14 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL dehydrogenase#PC00092 HUMAN|HGNC=20084|UniProtKB=Q8TDD1 Q8TDD1 DDX54 PTHR24031:SF292 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX54 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9794|UniProtKB=Q9UI14 Q9UI14 RABAC1 PTHR19317:SF0 PRENYLATED RAB ACCEPTOR 1-RELATED PRENYLATED RAB ACCEPTOR PROTEIN 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=34455|UniProtKB=A8MZG2 A8MZG2 C16orf90 PTHR37334:SF1 RGD1561796 RGD1561796 HUMAN|HGNC=3338|UniProtKB=Q14247 Q14247 CTTN PTHR10829:SF15 CORTACTIN AND DREBRIN SRC SUBSTRATE CORTACTIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;dendrite development#GO:0016358;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;dendritic spine organization#GO:0097061;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;protein-containing complex subunit organization#GO:0043933;positive regulation of growth#GO:0045927;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular protein-containing complex assembly#GO:0034622;neuron projection extension#GO:1990138;regulation of multicellular organismal process#GO:0051239;regulation of dendritic spine development#GO:0060998;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;synapse organization#GO:0050808;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;regulation of synapse structure or activity#GO:0050803;positive regulation of neuron projection development#GO:0010976;positive regulation of cell growth#GO:0030307;positive regulation of multicellular organismal process#GO:0051240;regulation of dendrite morphogenesis#GO:0048814;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;positive regulation of cell projection organization#GO:0031346;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;growth#GO:0040007;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;system development#GO:0048731;regulation of protein-containing complex assembly#GO:0043254;axon extension#GO:0048675;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;neuron differentiation#GO:0030182;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of protein polymerization#GO:0032271;cell part morphogenesis#GO:0032990;regulation of cell growth#GO:0001558;regulation of anatomical structure size#GO:0090066;positive regulation of neuron differentiation#GO:0045666;developmental cell growth#GO:0048588;developmental growth involved in morphogenesis#GO:0060560;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;developmental growth#GO:0048589;regulation of actin filament length#GO:0030832;multicellular organism development#GO:0007275;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;cell growth#GO:0016049;dendrite morphogenesis#GO:0048813;positive regulation of developmental process#GO:0051094;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of supramolecular fiber organization#GO:1902903;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cortical actin cytoskeleton#GO:0030864;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;integral component of membrane#GO:0016021;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;intrinsic component of membrane#GO:0031224;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;lamellipodium#GO:0030027;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;cortical cytoskeleton#GO:0030863;anchoring junction#GO:0070161;ion channel complex#GO:0034702;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;cell cortex#GO:0005938;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;neuron projection#GO:0043005;focal adhesion#GO:0005925;integral component of plasma membrane#GO:0005887;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856;site of polarized growth#GO:0030427;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 HUMAN|HGNC=8752|UniProtKB=Q9UKL6 Q9UKL6 PCTP PTHR19308:SF39 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN PHOSPHATIDYLCHOLINE TRANSFER PROTEIN HUMAN|HGNC=28247|UniProtKB=Q969E4 Q969E4 TCEAL3 PTHR14754:SF33 TRANSCRIPTION ELONGATION FACTOR A TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 3-RELATED general transcription factor#PC00259 HUMAN|HGNC=12983|UniProtKB=Q15776 Q15776 ZKSCAN8 PTHR23226:SF75 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 8 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=37164|UniProtKB=P0CJ74 P0CJ74 MTRNR2L7 PTHR33895:SF2 HUMANIN-LIKE 4 HUMANIN-LIKE 7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=24834|UniProtKB=Q5JY77 Q5JY77 GPRASP1 PTHR46414:SF3 PROTEIN BHLHB9-RELATED G-PROTEIN COUPLED RECEPTOR-ASSOCIATED SORTING PROTEIN 1 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=20856|UniProtKB=Q9NVV9 Q9NVV9 THAP1 PTHR46600:SF5 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=20957|UniProtKB=Q5VUM1 Q5VUM1 SDHAF4 PTHR28524:SF3 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL chaperone#PC00072 HUMAN|HGNC=18471|UniProtKB=Q9NPG8 Q9NPG8 ZDHHC4 PTHR22883:SF150 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC4 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=20246|UniProtKB=Q8WUD1 Q8WUD1 RAB2B PTHR47979:SF50 DRAB11-RELATED RAS-RELATED PROTEIN RAB-2B bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=33905|UniProtKB=A5A3E0 A5A3E0 POTEF PTHR24118:SF94 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER E-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=8011|UniProtKB=P78357 P78357 CNTNAP1 PTHR15036:SF43 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN 1 HUMAN|HGNC=16829|UniProtKB=O43818 O43818 RRP9 PTHR19865:SF0 U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2 U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 HUMAN|HGNC=8347|UniProtKB=Q13606 Q13606 OR5I1 PTHR48018:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5I1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=13431|UniProtKB=P0CI25 P0CI25 TRIM49 PTHR24103:SF637 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 49-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=16105|UniProtKB=Q9NX31 Q9NX31 OSER1 PTHR31383:SF2 OXIDATIVE STRESS-RESPONSE SERINE-RICH PROTEIN 1 OXIDATIVE STRESS-RESPONSIVE SERINE-RICH PROTEIN 1 response to stimulus#GO:0050896;cellular response to chemical stress#GO:0062197;cellular response to oxygen-containing compound#GO:1901701;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;response to stress#GO:0006950;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular response to stress#GO:0033554 HUMAN|HGNC=3808|UniProtKB=Q13461 Q13461 FOXE3 PTHR11829:SF156 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN E3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=8912|UniProtKB=P35232 P35232 PHB PTHR23222:SF37 PROHIBITIN PROHIBITIN HUMAN|HGNC=29272|UniProtKB=Q8NCU4 Q8NCU4 CCDC191 PTHR22028:SF5 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 191 HUMAN|HGNC=25294|UniProtKB=Q9H0D2 Q9H0D2 ZNF541 PTHR16089:SF23 REST COREPRESSOR COREST PROTEIN-RELATED ZINC FINGER PROTEIN 541 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 HUMAN|HGNC=2343|UniProtKB=P82279 P82279 CRB1 PTHR24049:SF1 CRUMBS FAMILY MEMBER PROTEIN CRUMBS HOMOLOG 1 establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;establishment or maintenance of bipolar cell polarity#GO:0061245 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=4027|UniProtKB=Q14802 Q14802 FXYD3 PTHR14132:SF11 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of sodium ion transport#GO:0002028;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;sodium ion transport#GO:0006814;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;sodium ion transmembrane transport#GO:0035725 primary active transporter#PC00068 HUMAN|HGNC=10490|UniProtKB=Q99584 Q99584 S100A13 PTHR11639:SF57 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A13 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of cell population proliferation#GO:0042127;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;extracellular region#GO:0005576;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=30087|UniProtKB=Q5T7W7 Q5T7W7 TSTD2 PTHR43268:SF6 THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2 THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2 transferase#PC00220 HUMAN|HGNC=28808|UniProtKB=Q63HQ0 Q63HQ0 AP1AR PTHR34529:SF1 AP-1 COMPLEX-ASSOCIATED REGULATORY PROTEIN AP-1 COMPLEX-ASSOCIATED REGULATORY PROTEIN HUMAN|HGNC=15213|UniProtKB=Q8NGH9 Q8NGH9 OR52E4 PTHR26450:SF13 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E4 transmembrane signal receptor#PC00197 HUMAN|HGNC=9106|UniProtKB=O60486 O60486 PLXNC1 PTHR22625:SF4 PLEXIN PLEXIN-C1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of GTPase activity#GO:0043087;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of neuron differentiation#GO:0045664;negative regulation of cell adhesion#GO:0007162;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;positive regulation of neuron projection development#GO:0010976;locomotion#GO:0040011;taxis#GO:0042330;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of cell projection organization#GO:0031346;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;biological adhesion#GO:0022610;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of cell adhesion#GO:0030155;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;positive regulation of neuron differentiation#GO:0045666;cellular response to stimulus#GO:0051716;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;cell migration#GO:0016477 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=15926|UniProtKB=Q9NZ72 Q9NZ72 STMN3 PTHR10104:SF17 STATHMIN STATHMIN-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cellular protein complex disassembly#GO:0043624;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=26686|UniProtKB=A6NNX1 A6NNX1 RIIAD1 PTHR15505:SF4 RIIA DOMAIN-CONTAINING PROTEIN 1 RIIA DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=24974|UniProtKB=Q8IZ69 Q8IZ69 TRMT2A PTHR45904:SF2 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A RNA methyltransferase#PC00033 HUMAN|HGNC=7126|UniProtKB=Q15773 Q15773 MLF2 PTHR13105:SF4 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR 2 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207 HUMAN|HGNC=11854|UniProtKB=P41732 P41732 TSPAN7 PTHR19282:SF257 TETRASPANIN TETRASPANIN-7 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=48334|UniProtKB=A6NHP3 A6NHP3 SPDYE2B PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=18838|UniProtKB=Q8WUF5 Q8WUF5 PPP1R13L PTHR24164:SF4 RELA-ASSOCIATED INHIBITOR RELA-ASSOCIATED INHIBITOR cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=9303|UniProtKB=P30154 P30154 PPP2R1B PTHR10648:SF9 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 65 KDA REGULATORY SUBUNIT A BETA ISOFORM-RELATED phosphatase binding#GO:0019902;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;protein serine/threonine phosphatase activity#GO:0004722;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 HUMAN|HGNC=37454|UniProtKB=E9PJ23 E9PJ23 NPIPB6 PTHR15438:SF4 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER B15-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=22223|UniProtKB=Q7L9B9 Q7L9B9 EEPD1 PTHR21180:SF32 ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1 ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=20290|UniProtKB=Q9H9S4 Q9H9S4 CAB39L PTHR10182:SF9 CALCIUM-BINDING PROTEIN 39-RELATED CALCIUM-BINDING PROTEIN 39-LIKE protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209;kinase binding#GO:0019900;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 HUMAN|HGNC=20372|UniProtKB=Q9NX14 Q9NX14 NDUFB11 PTHR13327:SF0 NADH-UBIQUINONE OXIDOREDUCTASE ESSS SUBUNIT, MITOCHONDRIAL PRECURSOR NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 11, MITOCHONDRIAL envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=15408|UniProtKB=P0C629 P0C629 OR10J4 PTHR26451:SF107 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10J4 HUMAN|HGNC=5555|UniProtKB=A0A0C4DH39 A0A0C4DH39 IGHV1-58 PTHR23266:SF270 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-58 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=8860|UniProtKB=O00628 O00628 PEX7 PTHR46027:SF1 PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein targeting to peroxisome#GO:0006625;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein localization to peroxisome#GO:0072662;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;peroxisomal matrix#GO:0005782;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6334|UniProtKB=P43631 P43631 KIR2DS2 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=11633|UniProtKB=P15923 P15923 TCF3 PTHR11793:SF7 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR E2-ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=18271|UniProtKB=Q8N8S7 Q8N8S7 ENAH PTHR11202:SF1 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER PROTEIN ENABLED HOMOLOG protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;neuron differentiation#GO:0030182;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;localization of cell#GO:0051674;actin polymerization or depolymerization#GO:0008154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell motility#GO:0048870;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;organelle organization#GO:0006996;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 scaffold/adaptor protein#PC00226 Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516;Axon guidance mediated by Slit/Robo#P00008>Mena#P00345;Axon guidance mediated by netrin#P00009>Ena#P00361 HUMAN|HGNC=25398|UniProtKB=Q86T26 Q86T26 TMPRSS11B PTHR24253:SF56 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11B serine protease#PC00203 HUMAN|HGNC=689|UniProtKB=Q9Y4X5 Q9Y4X5 ARIH1 PTHR11685:SF212 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH1 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=5652|UniProtKB=A0A075B6R2 A0A075B6R2 IGHV4-4 PTHR23266:SF364 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=14738|UniProtKB=Q8NGK1 Q8NGK1 OR51G1 PTHR26450:SF140 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51G1 transmembrane signal receptor#PC00197 HUMAN|HGNC=23746|UniProtKB=Q7Z6G3 Q7Z6G3 NECAB2 PTHR12178:SF2 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 2 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=7744|UniProtKB=Q96PY6 Q96PY6 NEK1 PTHR24361:SF613 MITOGEN-ACTIVATED KINASE KINASE KINASE SERINE/THREONINE-PROTEIN KINASE NEK1 HUMAN|HGNC=99|UniProtKB=Q16515 Q16515 ASIC2 PTHR11690:SF128 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=6038|UniProtKB=Q12906 Q12906 ILF3 PTHR45762:SF4 ZINC FINGER RNA-BINDING PROTEIN INTERLEUKIN ENHANCER-BINDING FACTOR 3 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=9964|UniProtKB=Q92785 Q92785 DPF2 PTHR10615:SF13 HISTONE ACETYLTRANSFERASE ZINC FINGER PROTEIN UBI-D4 molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=13374|UniProtKB=Q9H3V2 Q9H3V2 MS4A5 PTHR23320:SF54 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 5 transporter#PC00227 HUMAN|HGNC=23040|UniProtKB=Q5T5X7 Q5T5X7 BEND3 PTHR28665:SF1 BEN DOMAIN-CONTAINING PROTEIN 3 BEN DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=23847|UniProtKB=Q9P1Z0 Q9P1Z0 ZBTB4 PTHR24388:SF58 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=5958|UniProtKB=Q13123 Q13123 IK PTHR12765:SF7 RED PROTEIN IK FACTOR CYTOKINE IK PROTEIN RED cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 cytokine#PC00083 HUMAN|HGNC=17768|UniProtKB=O95551 O95551 TDP2 PTHR15822:SF4 TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN TYROSYL-DNA PHOSPHODIESTERASE 2 HUMAN|HGNC=20217|UniProtKB=Q9NVH0 Q9NVH0 EXD2 PTHR13620:SF96 3-5 EXONUCLEASE EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2-RELATED Lipoate_biosynthesis#P02750>Lipoyl-protein ligase#P03003 HUMAN|HGNC=17971|UniProtKB=Q9P0P8 Q9P0P8 MTRES1 PTHR13633:SF3 UNCHARACTERIZED MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26768|UniProtKB=Q8N954 Q8N954 GPATCH11 PTHR21032:SF0 UNCHARACTERIZED G PATCH DOMAIN-CONTAINING PROTEIN 11 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular#GO:0005622;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16439|UniProtKB=Q3SYA9 Q3SYA9 POM121L1P PTHR15566:SF4 POM121-LIKE POM121-LIKE PROTEIN 1-RELATED HUMAN|HGNC=44654|UniProtKB=H3BRN8 H3BRN8 C15orf65 PTHR20899:SF4 PIERCE HOMOLOG CELL CYCLE PROGRESSION 1, OPPOSITE STRAND HUMAN|HGNC=993|UniProtKB=Q9HD36 Q9HD36 BCL2L10 PTHR11256:SF47 BCL-2 RELATED BCL-2-LIKE PROTEIN 10 identical protein binding#GO:0042802;protein binding#GO:0005515;protein homodimerization activity#GO:0042803;binding#GO:0005488 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;cell death#GO:0008219;intracellular signal transduction#GO:0035556;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;negative regulation of cell death#GO:0060548;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of intrinsic apoptotic signaling pathway#GO:2001242;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>Diva#P00285 HUMAN|HGNC=28659|UniProtKB=Q6UWN0 Q6UWN0 LYPD4 PTHR16529:SF6 CD177 ANTIGEN LY6/PLAUR DOMAIN-CONTAINING PROTEIN 4 plasma membrane raft#GO:0044853;anchored component of plasma membrane#GO:0046658;intrinsic component of membrane#GO:0031224;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;membrane raft#GO:0045121;anchored component of membrane#GO:0031225;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane region#GO:0098589;membrane microdomain#GO:0098857;plasma membrane#GO:0005886;whole membrane#GO:0098805 HUMAN|HGNC=556|UniProtKB=O75843 O75843 AP1G2 PTHR22780:SF28 ADAPTIN, ALPHA/GAMMA/EPSILON AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network transport vesicle#GO:0030140;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=3229|UniProtKB=P01133 P01133 EGF PTHR46513:SF5 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED PRO-EPIDERMAL GROWTH FACTOR cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGF#P00549;Gonadotropin-releasing hormone receptor pathway#P06664>EGF#P06745 HUMAN|HGNC=3959|UniProtKB=Q92765 Q92765 FRZB PTHR11309:SF97 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;intracellular#GO:0005622;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>FRP#P00237;Wnt signaling pathway#P00057>FrzB#P01461 HUMAN|HGNC=5036|UniProtKB=Q14103 Q14103 HNRNPD PTHR48033:SF3 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=23665|UniProtKB=Q5TYW2 Q5TYW2 ANKRD20A1 PTHR24147:SF1 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 20A1-RELATED HUMAN|HGNC=20347|UniProtKB=Q9H9C1 Q9H9C1 VIPAS39 PTHR13364:SF6 DEFECTIVE SPERMATOGENESIS PROTEIN 39 SPERMATOGENESIS-DEFECTIVE PROTEIN 39 HOMOLOG cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9826|UniProtKB=Q92698 Q92698 RAD54L PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED HUMAN|HGNC=15993|UniProtKB=Q9H2A9 Q9H2A9 CHST8 PTHR12137:SF7 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 8 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=30631|UniProtKB=Q96BN2 Q96BN2 TADA1 PTHR21277:SF5 TRANSCRIPTIONAL ADAPTER 1 TRANSCRIPTIONAL ADAPTER 1 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear lumen#GO:0031981 HUMAN|HGNC=11645|UniProtKB=Q9UH92 Q9UH92 MLX PTHR15741:SF25 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MAX-LIKE PROTEIN X cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 HUMAN|HGNC=9552|UniProtKB=P62195 P62195 PSMC5 PTHR23073:SF12 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 8 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;TBP-class protein binding#GO:0017025 positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription, initiation#GO:2000142;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of transcription initiation from RNA polymerase II promoter#GO:0060260;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;positive regulation of transcription initiation from RNA polymerase II promoter#GO:0060261;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of protein-containing complex assembly#GO:0043254;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of RNA polymerase II transcription preinitiation complex assembly#GO:0045899;positive regulation of cellular component biogenesis#GO:0044089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of protein-containing complex assembly#GO:0031334;regulation of primary metabolic process#GO:0080090;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of DNA-templated transcription, initiation#GO:2000144;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;organelle lumen#GO:0043233;nucleus#GO:0005634;proteasome regulatory particle#GO:0005838;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;proteasome regulatory particle, base subcomplex#GO:0008540;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endopeptidase complex#GO:1905369;nuclear lumen#GO:0031981 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 HUMAN|HGNC=4476|UniProtKB=Q99679 Q99679 GPR21 PTHR24249:SF384 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 21-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=25979|UniProtKB=Q9NQG6 Q9NQG6 MIEF1 PTHR16451:SF12 MITOCHONDRIAL DYNAMICS PROTEINS 49/51 FAMILY MEMBER MITOCHONDRIAL DYNAMICS PROTEIN MID51 positive regulation of organelle organization#GO:0010638;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of mitochondrion organization#GO:0010821;organelle organization#GO:0006996;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;positive regulation of biological process#GO:0048518;mitochondrial fission#GO:0000266 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=7455|UniProtKB=P03886 P03886 MT-ND1 PTHR11432:SF3 NADH DEHYDROGENASE SUBUNIT 1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular respiration#GO:0045333;aerobic respiration#GO:0009060;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 dehydrogenase#PC00092 HUMAN|HGNC=6512|UniProtKB=Q9P2J5 Q9P2J5 LARS1 PTHR45794:SF1 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=25556|UniProtKB=Q9NVM6 Q9NVM6 DNAJC17 PTHR44313:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 chaperone#PC00072 HUMAN|HGNC=1354|UniProtKB=P07360 P07360 C8G PTHR47304:SF1 COMPLEMENT COMPONENT C8 GAMMA CHAIN COMPLEMENT COMPONENT C8 GAMMA CHAIN HUMAN|HGNC=5139|UniProtKB=P13378 P13378 HOXD8 PTHR46166:SF1 HOMEOBOX DOMAIN-CONTAINING PROTEIN HOMEOBOX PROTEIN HOX-D8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=29521|UniProtKB=Q99622 Q99622 C12orf57 PTHR13463:SF3 PROTEIN C10 PROTEIN C10 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;post-embryonic development#GO:0009791;multicellular organism development#GO:0007275;developmental process#GO:0032502 HUMAN|HGNC=8373|UniProtKB=O76099 O76099 OR7C1 PTHR48001:SF118 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7C1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=15802|UniProtKB=Q9BWX5 Q9BWX5 GATA5 PTHR10071:SF289 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cardiac muscle tissue development#GO:0048738;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;muscle tissue development#GO:0060537;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;striated muscle tissue development#GO:0014706;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=10994|UniProtKB=P50443 P50443 SLC26A2 PTHR11814:SF16 SULFATE TRANSPORTER SULFATE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;inorganic anion transmembrane transporter activity#GO:0015103;active ion transmembrane transporter activity#GO:0022853 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=1854|UniProtKB=Q03188 Q03188 CENPC PTHR16684:SF12 CENTROMERE PROTEIN C CENTROMERE PROTEIN C sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;kinetochore organization#GO:0051383;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;telophase#GO:0051326;protein-DNA complex assembly#GO:0065004;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;M phase#GO:0000279;metaphase plate congression#GO:0051310;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic sister chromatid segregation#GO:0000070;cell cycle phase#GO:0022403;kinetochore assembly#GO:0051382;establishment of organelle localization#GO:0051656;meiosis I#GO:0007127;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;nuclear chromosome segregation#GO:0098813;cellular protein-containing complex assembly#GO:0034622;meiosis I cell cycle phase#GO:0098764;establishment of chromosome localization#GO:0051303;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;mitotic metaphase plate congression#GO:0007080;chromosome localization#GO:0050000 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome kinetochore#GO:0000777;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;condensed nuclear chromosome kinetochore#GO:0000778;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 centromere DNA-binding protein#PC00071 HUMAN|HGNC=19152|UniProtKB=Q96M98 Q96M98 PACRG PTHR21207:SF2 PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED PARKIN COREGULATED GENE PROTEIN protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488;chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544;Hsp90 protein binding#GO:0051879 regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523 HUMAN|HGNC=23437|UniProtKB=Q96JD6 Q96JD6 AKR1E2 PTHR11732:SF391 ALDO/KETO REDUCTASE 1,5-ANHYDRO-D-FRUCTOSE REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=25265|UniProtKB=Q6NZY4 Q6NZY4 ZCCHC8 PTHR13316:SF0 ZINC FINGER, CCHC DOMAIN CONTAINING 8 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA metabolism protein#PC00031 HUMAN|HGNC=2023|UniProtKB=P51795 P51795 CLCN5 PTHR45711:SF7 CHLORIDE CHANNEL PROTEIN H(+)/CL(-) EXCHANGE TRANSPORTER 5 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;antiporter activity#GO:0015297;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;solute:cation antiporter activity#GO:0015298;gated channel activity#GO:0022836;proton transmembrane transporter activity#GO:0015078;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;solute:proton antiporter activity#GO:0015299;active ion transmembrane transporter activity#GO:0022853 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;Golgi apparatus#GO:0005794;early endosome#GO:0005769;cell junction#GO:0030054;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;intrinsic component of plasma membrane#GO:0031226;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=30728|UniProtKB=O95478 O95478 NSA2 PTHR12642:SF3 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 HUMAN|HGNC=17938|UniProtKB=Q9NYX4 Q9NYX4 CALY PTHR28546:SF1 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURON-SPECIFIC VESICULAR PROTEIN CALCYON protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 endosomal transport#GO:0016197;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cellular protein-containing complex assembly#GO:0034622;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex subunit organization#GO:0043933 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=17289|UniProtKB=Q96BJ8 Q96BJ8 ELMO3 PTHR12771:SF16 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 3 Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;locomotion#GO:0040011 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26453|UniProtKB=Q8NHS4 Q8NHS4 CLHC1 PTHR10292:SF11 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN LINKER DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cellular anatomical entity#GO:0110165;membrane#GO:0016020 vesicle coat protein#PC00235 HUMAN|HGNC=5244|UniProtKB=P38646 P38646 HSPA9 PTHR19375:SF184 HEAT SHOCK PROTEIN 70KDA STRESS-70 PROTEIN, MITOCHONDRIAL Parkinson disease#P00049>Hsp70#P01208 HUMAN|HGNC=5239|UniProtKB=P17066 P17066 HSPA6 PTHR19375:SF168 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524;ATPase activity#GO:0016887 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;chaperone-mediated protein folding#GO:0061077;cellular response to organic substance#GO:0071310;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;'de novo' protein folding#GO:0006458;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;COP9 signalosome#GO:0008180;vesicle#GO:0031982;intracellular organelle#GO:0043229 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 HUMAN|HGNC=25525|UniProtKB=Q9BTX1 Q9BTX1 NDC1 PTHR13269:SF6 UNCHARACTERIZED NUCLEOPORIN NDC1 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;protein-containing complex subunit organization#GO:0043933 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=23015|UniProtKB=Q96MK3 Q96MK3 FAM20A PTHR12450:SF12 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 PSEUDOKINASE FAM20A protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;protein kinase activity#GO:0004672;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=27678|UniProtKB=Q86YG4 Q86YG4 NT5DC4 PTHR12103:SF18 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173 HUMAN|HGNC=27753|UniProtKB=A6NFR6 A6NFR6 C5orf60 PTHR21859:SF42 ACROSOME-SPECIFIC PROTEIN SUBFAMILY NOT NAMED HUMAN|HGNC=24376|UniProtKB=Q6BCY4 Q6BCY4 CYB5R2 PTHR19370:SF108 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE 2 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 reductase#PC00198 HUMAN|HGNC=855|UniProtKB=P27449 P27449 ATP6V0C PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 ATP synthase#PC00002 HUMAN|HGNC=2762|UniProtKB=P59666 P59666 DEFA3 PTHR11876:SF19 ALPHA-DEFENSIN 1 NEUTROPHIL DEFENSIN 1-RELATED response to external biotic stimulus#GO:0043207;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;antibacterial humoral response#GO:0019731;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;innate immune response#GO:0045087;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cellular response to biotic stimulus#GO:0071216;cellular process#GO:0009987;defense response to Gram-positive bacterium#GO:0050830;response to lipopolysaccharide#GO:0032496;defense response to Gram-negative bacterium#GO:0050829;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=30403|UniProtKB=Q9H7N4 Q9H7N4 SCAF1 PTHR47013:SF1 SPLICING FACTOR, ARGININE/SERINE-RICH 19 SPLICING FACTOR, ARGININE/SERINE-RICH 19 basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 RNA splicing factor#PC00148 HUMAN|HGNC=18309|UniProtKB=Q9NWH7 Q9NWH7 SPATA6 PTHR16435:SF3 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 HUMAN|HGNC=21427|UniProtKB=A6NDV4 A6NDV4 TMEM8B PTHR14319:SF6 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 TRANSMEMBRANE PROTEIN 8B cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=11335|UniProtKB=Q16384 Q16384 SSX1 PTHR14112:SF26 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=12719|UniProtKB=Q86Y07 Q86Y07 VRK2 PTHR11909:SF100 CASEIN KINASE-RELATED SERINE/THREONINE-PROTEIN KINASE VRK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;transport#GO:0006810;positive regulation of proteasomal protein catabolic process#GO:1901800;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of protein catabolic process#GO:0042176;positive regulation of Wnt signaling pathway#GO:0030177;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;vesicle organization#GO:0016050;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;canonical Wnt signaling pathway#GO:0060070;regulation of cellular protein catabolic process#GO:1903362;signaling#GO:0023052;cell-cell signaling#GO:0007267;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;Wnt signaling pathway#GO:0016055;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;vesicle budding from membrane#GO:0006900;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=13518|UniProtKB=Q9Y696 Q9Y696 CLIC4 PTHR43920:SF7 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL PROTEIN 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ion channel#PC00133 HUMAN|HGNC=2916|UniProtKB=O60479 O60479 DLX3 PTHR24327:SF28 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;epithelium development#GO:0060429;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=9445|UniProtKB=P01236 P01236 PRL PTHR11417:SF5 SOMATOTROPIN,PROLACTIN PROLACTIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of cell population proliferation#GO:0008284;response to extracellular stimulus#GO:0009991;cell population proliferation#GO:0008283;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;positive regulation of receptor signaling pathway via STAT#GO:1904894;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;receptor signaling pathway via JAK-STAT#GO:0007259;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;receptor signaling pathway via STAT#GO:0097696;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of receptor signaling pathway via JAK-STAT#GO:0046425 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>Prolactin#P06789 HUMAN|HGNC=1242|UniProtKB=P02746 P02746 C1QB PTHR15427:SF18 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT B HUMAN|HGNC=31022|UniProtKB=Q9BTL3 Q9BTL3 RAMAC PTHR48168:SF1 RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED HUMAN|HGNC=7627|UniProtKB=Q15742 Q15742 NAB2 PTHR12623:SF6 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 Gonadotropin-releasing hormone receptor pathway#P06664>NAB#P06801 HUMAN|HGNC=14697|UniProtKB=Q8NH37 Q8NH37 OR4C3 PTHR48002:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C3 transmembrane signal receptor#PC00197 HUMAN|HGNC=11002|UniProtKB=O43868 O43868 SLC28A2 PTHR10590:SF11 SODIUM/NUCLEOSIDE COTRANSPORTER SODIUM/NUCLEOSIDE COTRANSPORTER 2 carbohydrate derivative transmembrane transporter activity#GO:1901505;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;nucleoside transmembrane transporter activity#GO:0005337;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;nucleobase-containing compound transmembrane transporter activity#GO:0015932;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 transmembrane transport#GO:0055085;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;multicellular organismal homeostasis#GO:0048871;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;tissue homeostasis#GO:0001894;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;carbohydrate derivative transport#GO:1901264;anatomical structure homeostasis#GO:0060249 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=12154|UniProtKB=A0A087WT02 A0A087WT02 TRAV9-2 PTHR23267:SF449 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 9-2 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=3403|UniProtKB=P32856 P32856 STX2 PTHR19957:SF36 SYNTAXIN SYNTAXIN-2 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulated exocytosis#GO:0045055;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;protein localization to cell junction#GO:1902414;regulation of neurotransmitter levels#GO:0001505;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003;protein-containing complex localization#GO:0031503 synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;SNARE complex#GO:0031201;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;presynaptic membrane#GO:0042734;vesicle#GO:0031982;intracellular organelle#GO:0043229;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;plasma membrane region#GO:0098590;postsynapse#GO:0098794;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 SNARE protein#PC00034 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 HUMAN|HGNC=26542|UniProtKB=Q5T2T1 Q5T2T1 MPP7 PTHR23122:SF39 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 7 scaffold/adaptor protein#PC00226 HUMAN|HGNC=24648|UniProtKB=Q9NY74 Q9NY74 ETAA1 PTHR16434:SF2 EWING'S TUMOR-ASSOCIATED ANTIGEN 1 ETAA1 EWING'S TUMOR-ASSOCIATED ANTIGEN 1 HUMAN|HGNC=4379|UniProtKB=P29992 P29992 GNA11 PTHR10218:SF328 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-11 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 positive regulation of lipase activity#GO:0060193;regulation of adenylate cyclase activity#GO:0045761;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;action potential#GO:0001508;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;dopamine receptor signaling pathway#GO:0007212;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of phospholipase C activity#GO:1900274;regulation of membrane potential#GO:0042391;positive regulation of phospholipase activity#GO:0010518;trans-synaptic signaling#GO:0099537;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117 Endothelin signaling pathway#P00019>Gq#P00586;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Gonadotropin-releasing hormone receptor pathway#P06664>gnaq/11#P06841;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Alpha adrenergic receptor signaling pathway#P00002>G-Protein#P00077;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Wnt signaling pathway#P00057>Galpha#P01451;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;PI3 kinase pathway#P00048>Galpha#P01199 HUMAN|HGNC=26108|UniProtKB=Q8N3C7 Q8N3C7 CLIP4 PTHR18916:SF32 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 chaperone#PC00072 HUMAN|HGNC=14348|UniProtKB=O43464 O43464 HTRA2 PTHR22939:SF127 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA2, MITOCHONDRIAL serine protease#PC00203 HUMAN|HGNC=20189|UniProtKB=Q9NVL8 Q9NVL8 CCDC198 PTHR16065:SF2 COILED-COIL DOMAIN CONTAINING 198 COILED-COIL DOMAIN CONTAINING 198 HUMAN|HGNC=5598|UniProtKB=A0A0C4DH35 A0A0C4DH35 IGHV3-35 PTHR23266:SF204 IMMUNOGLOBULIN HEAVY CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=29446|UniProtKB=Q9H4I8 Q9H4I8 SERHL2 PTHR43329:SF72 EPOXIDE HYDROLASE SERINE HYDROLASE-LIKE PROTEIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=33920|UniProtKB=Q6IEE8 Q6IEE8 SLFN12L PTHR12155:SF2 SCHLAFEN SCHLAFEN FAMILY MEMBER 12-LIKE HUMAN|HGNC=32296|UniProtKB=Q6P047 Q6P047 C8orf74 PTHR28457:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 SIMILAR TO 4930578I06RIK PROTEIN HUMAN|HGNC=5472|UniProtKB=P17936 P17936 IGFBP3 PTHR11551:SF3 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 3 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 p53 pathway#P00059>IGF-BP3#G04691 HUMAN|HGNC=24714|UniProtKB=Q8IWZ3 Q8IWZ3 ANKHD1 PTHR23206:SF5 MASK PROTEIN ANKYRIN REPEAT AND KH DOMAIN-CONTAINING PROTEIN 1 response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;immune response#GO:0006955;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;defense response#GO:0006952 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 defense/immunity protein#PC00090 HUMAN|HGNC=6053|UniProtKB=P12268 P12268 IMPDH2 PTHR11911:SF121 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine nucleoside triphosphate biosynthetic process#GO:0009145;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside triphosphate biosynthetic process#GO:0009142;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 HUMAN|HGNC=28583|UniProtKB=Q6UXX9 Q6UXX9 RSPO2 PTHR46987:SF4 FAMILY NOT NAMED R-SPONDIN-2 HUMAN|HGNC=3247|UniProtKB=Q08426 Q08426 EHHADH PTHR23309:SF49 3-HYDROXYACYL-COA DEHYROGENASE PEROXISOMAL BIFUNCTIONAL ENZYME catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092 HUMAN|HGNC=14705|UniProtKB=Q8NGB4 Q8NGB4 OR4S1 PTHR48002:SF81 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4S1 transmembrane signal receptor#PC00197 HUMAN|HGNC=6090|UniProtKB=Q01101 Q01101 INSM1 PTHR15065:SF5 INSULINOMA-ASSOCIATED 1 INSULINOMA-ASSOCIATED PROTEIN 1 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229 HUMAN|HGNC=13018|UniProtKB=Q9UK10 Q9UK10 ZNF225 PTHR24376:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 224-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=10944|UniProtKB=P48664 P48664 SLC1A6 PTHR11958:SF67 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 4 primary active transporter#PC00068 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 HUMAN|HGNC=17928|UniProtKB=Q9P2W1 Q9P2W1 PSMC3IP PTHR15938:SF0 TBP-1 INTERACTING PROTEIN HOMOLOGOUS-PAIRING PROTEIN 2 HOMOLOG DNA metabolism protein#PC00009 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription by RNA polymerase I#P00022>TBP#P00657;General transcription regulation#P00023>TBP#P00670;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 HUMAN|HGNC=12641|UniProtKB=Q9UBK9 Q9UBK9 UXT PTHR13345:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 PROTEIN UXT molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=6678|UniProtKB=P22079 P22079 LPO PTHR11475:SF67 OXIDASE/PEROXIDASE LACTOPEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180 HUMAN|HGNC=12560|UniProtKB=Q5DID0 Q5DID0 UMODL1 PTHR14002:SF22 ENDOGLIN/TGF-BETA RECEPTOR TYPE III UROMODULIN-LIKE 1 transmembrane signal receptor#PC00197 HUMAN|HGNC=11246|UniProtKB=O43278 O43278 SPINT1 PTHR46750:SF1 KUNITZ-TYPE PROTEASE INHIBITOR 1 KUNITZ-TYPE PROTEASE INHIBITOR 1 protease inhibitor#PC00191 HUMAN|HGNC=17754|UniProtKB=Q9NS62 Q9NS62 THSD1 PTHR16311:SF3 THROMBOSPONDIN TYPE I DOMAIN-CONTAINING 1 THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 HUMAN|HGNC=24564|UniProtKB=Q4AC94 Q4AC94 C2CD3 PTHR21254:SF1 UNCHARACTERIZED C2 DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=8343|UniProtKB=O95221 O95221 OR5F1 PTHR26452:SF769 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5F1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=9469|UniProtKB=O14668 O14668 PRRG1 PTHR24251:SF14 OVOCHYMASE-RELATED TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 1 serine protease#PC00203 HUMAN|HGNC=12915|UniProtKB=P52739 P52739 ZNF131 PTHR24399:SF35 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER PROTEIN 131 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7377|UniProtKB=Q9UJ68 Q9UJ68 MSRA PTHR42799:SF2 MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 response to stimulus#GO:0050896;cellular response to chemical stress#GO:0062197;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=25994|UniProtKB=Q08J23 Q08J23 NSUN2 PTHR22808:SF20 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING RNA CYTOSINE C(5)-METHYLTRANSFERASE NSUN2 tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 HUMAN|HGNC=34407|UniProtKB=Q2L4Q9 Q2L4Q9 PRSS53 PTHR24276:SF61 POLYSERASE-RELATED SERINE PROTEASE 53 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 HUMAN|HGNC=9543|UniProtKB=P28072 P28072 PSMB6 PTHR11599:SF46 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-6 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 HUMAN|HGNC=27365|UniProtKB=Q5HYJ1 Q5HYJ1 TECRL PTHR10556:SF27 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE TRANS-2,3-ENOYL-COA REDUCTASE-LIKE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092 HUMAN|HGNC=26276|UniProtKB=Q7Z624 Q7Z624 CAMKMT PTHR13539:SF3 CALMODULIN-LYSINE N-METHYLTRANSFERASE CALMODULIN-LYSINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 protein modifying enzyme#PC00260 HUMAN|HGNC=25412|UniProtKB=Q9BQI5 Q9BQI5 SGIP1 PTHR23065:SF27 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 SH3-CONTAINING GRB2-LIKE PROTEIN 3-INTERACTING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;protein-containing complex subunit organization#GO:0043933 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=15710|UniProtKB=O75112 O75112 LDB3 PTHR24214:SF9 PDZ AND LIM DOMAIN PROTEIN ZASP LIM DOMAIN-BINDING PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=24936|UniProtKB=Q96AZ1 Q96AZ1 EEF1AKMT3 PTHR14614:SF5 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN EEF1A LYSINE METHYLTRANSFERASE 3 N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein alkylation#GO:0008213;protein methylation#GO:0006479;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=17509|UniProtKB=Q9BXL5 Q9BXL5 HEMGN PTHR15993:SF6 HEMOGEN HEMOGEN HUMAN|HGNC=27540|UniProtKB=Q86VI1 Q86VI1 EXOC3L1 PTHR21292:SF12 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;vesicle organization#GO:0016050;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 membrane traffic protein#PC00150 HUMAN|HGNC=4979|UniProtKB=P50219 P50219 MNX1 PTHR24335:SF3 MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN 1 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;central nervous system development#GO:0007417;plasma membrane bounded cell projection morphogenesis#GO:0120039;generation of neurons#GO:0048699;cell part morphogenesis#GO:0032990 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=2067|UniProtKB=O00151 O00151 PDLIM1 PTHR24214:SF5 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=30099|UniProtKB=Q8NG41 Q8NG41 NPB PTHR28553:SF1 NEUROPEPTIDE B NEUROPEPTIDE B protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;behavior#GO:0007610;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 HUMAN|HGNC=44|UniProtKB=Q03519 Q03519 TAP2 PTHR24221:SF237 ATP-BINDING CASSETTE SUB-FAMILY B ANTIGEN PEPTIDE TRANSPORTER 2 binding#GO:0005488;catalytic activity#GO:0003824;MHC protein binding#GO:0042287;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;signaling receptor binding#GO:0005102;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;hydrolase activity#GO:0016787;amide transmembrane transporter activity#GO:0042887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;peptide transmembrane transporter activity#GO:1904680;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 localization#GO:0051179;antigen processing and presentation#GO:0019882;immune system process#GO:0002376;transmembrane transport#GO:0055085;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=23246|UniProtKB=Q86TC9 Q86TC9 MYPN PTHR10075:SF28 BASIGIN RELATED MYOPALLADIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=31007|UniProtKB=Q3SY89 Q3SY89 ELOA3B PTHR15141:SF74 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN-A3-RELATED HUMAN|HGNC=20090|UniProtKB=Q96KC8 Q96KC8 DNAJC1 PTHR44653:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 chaperone#PC00072 HUMAN|HGNC=3678|UniProtKB=Q9NSA1 Q9NSA1 FGF21 PTHR11486:SF81 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 21 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 HUMAN|HGNC=30768|UniProtKB=Q8TD23 Q8TD23 ZNF675 PTHR24384:SF115 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 675 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=19038|UniProtKB=Q86TW2 Q86TW2 ADCK1 PTHR43173:SF19 ABC1 FAMILY PROTEIN AARF DOMAIN-CONTAINING PROTEIN KINASE 1 cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;chemical homeostasis#GO:0048878 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=21591|UniProtKB=Q96LR4 Q96LR4 TAFA4 PTHR31770:SF7 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-4 receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=24140|UniProtKB=Q3V5L5 Q3V5L5 MGAT5B PTHR15075:SF6 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=21361|UniProtKB=Q5TGL8 Q5TGL8 PXDC1 PTHR31433:SF0 PX DOMAIN-CONTAINING PROTEIN 1 PX DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=28051|UniProtKB=Q5TID7 Q5TID7 CCDC181 PTHR14320:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 HUMAN|HGNC=30322|UniProtKB=Q8N1W1 Q8N1W1 ARHGEF28 PTHR13944:SF22 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 28 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;Rho protein signal transduction#GO:0007266;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;regulation of Ras protein signal transduction#GO:0046578;signaling#GO:0023052 CCKR signaling map#P06959>p190RhoGEF#P07157 HUMAN|HGNC=32206|UniProtKB=A6NDK9 A6NDK9 GOLGA6C PTHR10881:SF44 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 6A-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=17731|UniProtKB=Q8N2M8 Q8N2M8 CLASRP PTHR13161:SF4 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT CLK4-ASSOCIATING SERINE/ARGININE RICH PROTEIN RNA splicing factor#PC00148 HUMAN|HGNC=21649|UniProtKB=Q9UHR4 Q9UHR4 BAIAP2L1 PTHR14206:SF4 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2-LIKE PROTEIN 1 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;actin cytoskeleton reorganization#GO:0031532;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=21210|UniProtKB=Q16609 Q16609 LPAL2 PTHR24261:SF2 PLASMINOGEN-RELATED APOLIPOPROTEIN(A)-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 Plasminogen activating cascade#P00050>Plasminogen#P01255;Plasminogen activating cascade#P00050>Plasmin#P01246 HUMAN|HGNC=10011|UniProtKB=Q15382 Q15382 RHEB PTHR24070:SF264 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RHEB GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 p53 pathway by glucose deprivation#P04397>Rheb#P04642;CCKR signaling map#P06959>RHEB-GTP#P07224;CCKR signaling map#P06959>RHEB-GDP#P07175 HUMAN|HGNC=5136|UniProtKB=P35453 P35453 HOXD13 PTHR45804:SF4 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-D13 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=16432|UniProtKB=O14977 O14977 AZIN1 PTHR11482:SF7 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ANTIZYME INHIBITOR 1 carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;ornithine decarboxylase activity#GO:0004586;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234 negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;regulation of localization#GO:0032879;regulation of protein catabolic process#GO:0042176;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;positive regulation of transmembrane transport#GO:0034764;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;macromolecule catabolic process#GO:0009057;regulation of transmembrane transport#GO:0034762;transmembrane transport#GO:0055085;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of transport#GO:0051050;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 HUMAN|Ensembl=ENSG00000277596|UniProtKB=A0A0G2JP03 A0A0G2JP03 ENSG00000277596 PTHR11738:SF177 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL3 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=21561|UniProtKB=Q8IYX8 Q8IYX8 CEP57L1 PTHR19336:SF10 UNCHARACTERIZED DUF1167 CENTROSOMAL PROTEIN CEP57L1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=29067|UniProtKB=Q96AA8 Q96AA8 JAKMIP2 PTHR18935:SF7 UNCHARACTERIZED JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 2 HUMAN|HGNC=15294|UniProtKB=Q8NGP3 Q8NGP3 OR5M9 PTHR48018:SF132 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=5552|UniProtKB=A0A0C4DH29 A0A0C4DH29 IGHV1-3 PTHR23266:SF278 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-3 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=6460|UniProtKB=P78385 P78385 KRT83 PTHR45616:SF55 FAMILY NOT NAMED KERATIN, TYPE II CUTICULAR HB3 HUMAN|HGNC=25467|UniProtKB=Q96ST2 Q96ST2 IWS1 PTHR46010:SF1 PROTEIN IWS1 HOMOLOG PROTEIN IWS1 HOMOLOG cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;histone methylation#GO:0016571;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;regulation of biological process#GO:0050789;protein alkylation#GO:0008213;protein methylation#GO:0006479;mRNA metabolic process#GO:0016071;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;regulation of chromatin organization#GO:1902275;cellular protein metabolic process#GO:0044267;nuclear transport#GO:0051169;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;histone modification#GO:0016570;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;regulation of cellular localization#GO:0060341;peptide transport#GO:0015833;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;macromolecule methylation#GO:0043414;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;protein transport#GO:0015031;peptidyl-lysine trimethylation#GO:0018023;chromatin organization#GO:0006325;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of peptide transport#GO:0090087;protein-containing complex localization#GO:0031503;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nucleic acid transport#GO:0050657;RNA processing#GO:0006396;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of histone modification#GO:0031056;ribonucleoprotein complex export from nucleus#GO:0071426;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;regulation of transport#GO:0051049;organic cyclic compound metabolic process#GO:1901360;regulation of mRNA processing#GO:0050684;protein export from nucleus#GO:0006611;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;regulation of protein transport#GO:0051223;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;mRNA export from nucleus#GO:0006406;heterocycle metabolic process#GO:0046483;peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;organonitrogen compound metabolic process#GO:1901564;covalent chromatin modification#GO:0016569;histone lysine methylation#GO:0034968;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;mRNA transport#GO:0051028;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;nucleocytoplasmic transport#GO:0006913;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;mRNA processing#GO:0006397;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;RNA export from nucleus#GO:0006405 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=15319|UniProtKB=Q8NH87 Q8NH87 OR9G1 PTHR24242:SF158 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 9G1-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=20311|UniProtKB=Q96JM3 Q96JM3 CHAMP1 PTHR37354:SF1 CHROMOSOME ALIGNMENT-MAINTAINING PHOSPHOPROTEIN 1 CHROMOSOME ALIGNMENT-MAINTAINING PHOSPHOPROTEIN 1 HUMAN|HGNC=5048|UniProtKB=Q00839 Q00839 HNRNPU PTHR12381:SF11 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;double-stranded DNA binding#GO:0003690;enzyme binding#GO:0019899;sequence-specific double-stranded DNA binding#GO:1990837;RNA binding#GO:0003723;RNA polymerase binding#GO:0070063;organic cyclic compound binding#GO:0097159;transcription corepressor activity#GO:0003714;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II complex binding#GO:0000993;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;basal transcription machinery binding#GO:0001098;cis-regulatory region sequence-specific DNA binding#GO:0000987;single-stranded RNA binding#GO:0003727;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;pre-mRNA binding#GO:0036002;snRNA binding#GO:0017069;transcription factor binding#GO:0008134;sequence-specific DNA binding#GO:0043565;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;basal RNA polymerase II transcription machinery binding#GO:0001099;ribonucleoprotein complex binding#GO:0043021;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;protein binding#GO:0005515 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;cellular component biogenesis#GO:0044085;organelle localization#GO:0051640;heterocycle catabolic process#GO:0046700;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of localization#GO:0032879;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;regulation of telomere maintenance#GO:0032204;nucleobase-containing compound metabolic process#GO:0006139;telomere-telomerase complex assembly#GO:1905324;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;regulation of cellular component biogenesis#GO:0044087;regulation of mitotic sister chromatid segregation#GO:0033047;positive regulation of mitotic cell cycle#GO:0045931;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;attachment of spindle microtubules to kinetochore#GO:0008608;regulation of chromatin organization#GO:1902275;spindle organization#GO:0007051;establishment of organelle localization#GO:0051656;mRNA stabilization#GO:0048255;protein-containing complex subunit organization#GO:0043933;macromolecule catabolic process#GO:0009057;cellular protein-containing complex assembly#GO:0034622;sister chromatid segregation#GO:0000819;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;RNA splicing#GO:0008380;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;mitotic metaphase plate congression#GO:0007080;nucleobase-containing compound catabolic process#GO:0034655;chromosome localization#GO:0050000;cellular aromatic compound metabolic process#GO:0006725;regulation of microtubule-based process#GO:0032886;negative regulation of biological process#GO:0048519;mitotic spindle organization#GO:0007052;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;telomere organization#GO:0032200;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;biosynthetic process#GO:0009058;regulation of mitotic spindle organization#GO:0060236;telomere maintenance#GO:0000723;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of cell cycle process#GO:0090068;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;negative regulation of organelle organization#GO:0010639;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic spindle assembly#GO:0090307;positive regulation of macromolecule biosynthetic process#GO:0010557;alternative mRNA splicing, via spliceosome#GO:0000380;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;regulation of macromolecule biosynthetic process#GO:0010556;telomere maintenance via telomerase#GO:0007004;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;mRNA splicing, via spliceosome#GO:0000398;regulation of chromosome organization#GO:0033044;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;regulation of nuclear division#GO:0051783;negative regulation of cellular catabolic process#GO:0031330;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of catabolic process#GO:0009895;aromatic compound catabolic process#GO:0019439;regulation of nucleobase-containing compound metabolic process#GO:0019219;mRNA processing#GO:0006397;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;RNA splicing, via transesterification reactions#GO:0000375;positive regulation of nucleic acid-templated transcription#GO:1903508;cellular macromolecule catabolic process#GO:0044265;regulation of mitotic cell cycle#GO:0007346;transcription by RNA polymerase II#GO:0006366;telomere maintenance via telomere lengthening#GO:0010833;negative regulation of gene expression#GO:0010629;cellular localization#GO:0051641;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;protein-DNA complex assembly#GO:0065004;RNA localization#GO:0006403;transcription, DNA-templated#GO:0006351;regulation of telomere maintenance via telomerase#GO:0032210;mRNA metabolic process#GO:0016071;establishment of localization#GO:0051234;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;nuclear chromosome segregation#GO:0098813;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;RNA biosynthetic process#GO:0032774;regulation of RNA stability#GO:0043487;regulation of cellular localization#GO:0060341;positive regulation of cellular process#GO:0048522;RNA-dependent DNA biosynthetic process#GO:0006278;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;regulation of mRNA catabolic process#GO:0061013;macromolecule localization#GO:0033036;positive regulation of organelle organization#GO:0010638;regulation of mRNA stability#GO:0043488;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;mitotic cell cycle process#GO:1903047;regulation of transcription, DNA-templated#GO:0006355;metaphase plate congression#GO:0051310;positive regulation of metabolic process#GO:0009893;regulation of microtubule cytoskeleton organization#GO:0070507;RNA catabolic process#GO:0006401;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure homeostasis#GO:0060249;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;establishment of chromosome localization#GO:0051303;positive regulation of mitotic nuclear division#GO:0045840;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;organelle assembly#GO:0070925;regulation of RNA splicing#GO:0043484;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;microtubule-based process#GO:0007017;regulation of telomere maintenance via telomere lengthening#GO:1904356;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;chromosome, centromeric region#GO:0000775;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;centrosome#GO:0005813;nuclear periphery#GO:0034399;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;small nuclear ribonucleoprotein complex#GO:0030532;mitotic spindle#GO:0072686;intracellular#GO:0005622;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114;spindle#GO:0005819;microtubule#GO:0005874;membrane-enclosed lumen#GO:0031974;catalytic step 2 spliceosome#GO:0071013;microtubule organizing center#GO:0005815;spindle microtubule#GO:0005876;organelle lumen#GO:0043233;nucleus#GO:0005634;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;mitotic spindle midzone#GO:1990023;RNA polymerase II transcription regulator complex#GO:0090575;supramolecular fiber#GO:0099512;membrane#GO:0016020;nuclear body#GO:0016604;centriole#GO:0005814;polymeric cytoskeletal fiber#GO:0099513;cytoplasmic ribonucleoprotein granule#GO:0036464;U5 snRNP#GO:0005682;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;telomerase holoenzyme complex#GO:0005697 HUMAN|HGNC=13012|UniProtKB=P17026 P17026 ZNF22 PTHR24381:SF374 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 22 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=33941|UniProtKB=P0CK96 P0CK96 SLC35E2B PTHR11132:SF279 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E2A-RELATED secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=10953|UniProtKB=Q96BD0 Q96BD0 SLCO4A1 PTHR11388:SF146 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 4A1 secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=6886|UniProtKB=P45984 P45984 MAPK9 PTHR24055:SF172 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 9 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;MAPK cascade#GO:0000165;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;JNK cascade#GO:0007254;stress-activated MAPK cascade#GO:0051403;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;stress-activated protein kinase signaling cascade#GO:0031098;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Integrin signalling pathway#P00034>Jnk#P00951;TGF-beta signaling pathway#P00052>JNK#P01284;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>JNK1-3#P00545;CCKR signaling map#P06959>MAPK8-10#P07090;FGF signaling pathway#P00021>JNK1-3#P00628;FAS signaling pathway#P00020>JNK#P00615;Oxidative stress response#P00046>JNK1/2#P01129;Ras Pathway#P04393>JNK#P04572;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Huntington disease#P00029>JNK-2#P00799;Apoptosis signaling pathway#P00006>JNK#P00274;Toll receptor signaling pathway#P00054>JNK#P01375;B cell activation#P00010>Jnk#P00402;Parkinson disease#P00049>SAPK#P01219;T cell activation#P00053>Jnk#P01336;Gonadotropin-releasing hormone receptor pathway#P06664>JNK1/2#P06847 HUMAN|HGNC=8619|UniProtKB=Q02548 Q02548 PAX5 PTHR45636:SF20 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=9285|UniProtKB=O60927 O60927 PPP1R11 PTHR20835:SF4 E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED E3 UBIQUITIN-PROTEIN LIGASE PPP1R11 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;protein phosphatase 1 binding#GO:0008157;enzyme inhibitor activity#GO:0004857;phosphatase inhibitor activity#GO:0019212;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;protein phosphatase inhibitor activity#GO:0004864;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of protein dephosphorylation#GO:0035308;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;negative regulation of phosphatase activity#GO:0010923;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;regulation of phosphoprotein phosphatase activity#GO:0043666;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;regulation of phosphatase activity#GO:0010921;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of dephosphorylation#GO:0035305;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=3815|UniProtKB=Q12951 Q12951 FOXI1 PTHR11829:SF180 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN I1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=26719|UniProtKB=Q8N9N7 Q8N9N7 LRRC57 PTHR16083:SF21 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57 HUMAN|HGNC=4908|UniProtKB=Q6NVY1 Q6NVY1 HIBCH PTHR43176:SF15 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 hydrolase#PC00121 HUMAN|HGNC=8728|UniProtKB=P22061 P22061 PCMT1 PTHR11579:SF7 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 methyltransferase#PC00155 HUMAN|HGNC=12845|UniProtKB=O60688 O60688 YPEL1 PTHR13848:SF1 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 1 HUMAN|HGNC=6397|UniProtKB=O00629 O00629 KPNA4 PTHR23316:SF7 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-3 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=16921|UniProtKB=Q99490 Q99490 AGAP2 PTHR45819:SF3 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=37231|UniProtKB=B4DS77 B4DS77 SHISA9 PTHR31774:SF1 PROTEIN SHISA-9-RELATED PROTEIN SHISA-9 signal transduction#GO:0007165;regulation of neurotransmitter receptor activity#GO:0099601;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;ionotropic glutamate receptor signaling pathway#GO:0035235;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of AMPA receptor activity#GO:2000311;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;ion transmembrane transport#GO:0034220;regulation of synaptic plasticity#GO:0048167;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of signaling receptor activity#GO:0010469;response to stimulus#GO:0050896;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of trans-synaptic signaling#GO:0099177 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;leading edge membrane#GO:0031256;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;ion channel complex#GO:0034702;cell junction#GO:0030054;cell projection membrane#GO:0031253;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 HUMAN|HGNC=14504|UniProtKB=P82914 P82914 MRPS15 PTHR46685:SF1 28S RIBOSOMAL PROTEIN S15, MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S15, MITOCHONDRIAL ribosomal protein#PC00202 HUMAN|HGNC=15837|UniProtKB=Q96GQ7 Q96GQ7 DDX27 PTHR24031:SF706 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX27-RELATED intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26635|UniProtKB=Q8IWF6 Q8IWF6 DENND6A PTHR13677:SF1 UNCHARACTERIZED PROTEIN DENND6A Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=32310|UniProtKB=Q8IXT5 Q8IXT5 RBM12B PTHR13976:SF28 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RNA-BINDING PROTEIN 12B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=28674|UniProtKB=Q9BSK0 Q9BSK0 MARVELD1 PTHR22776:SF28 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN 1 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=5321|UniProtKB=Q12891 Q12891 HYAL2 PTHR11769:SF6 HYALURONIDASE HYALURONIDASE-2 glycosidase#PC00110 HUMAN|HGNC=15851|UniProtKB=Q96P71 Q96P71 NECAB3 PTHR12178:SF3 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 3 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=1543|UniProtKB=P23435 P23435 CBLN1 PTHR22923:SF5 CEREBELLIN-RELATED CEREBELLIN-1 HUMAN|HGNC=13114|UniProtKB=Q96MX3 Q96MX3 ZNF48 PTHR24376:SF73 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 48 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=41982|UniProtKB=E9PJI5 E9PJI5 NPIPA7 PTHR15438:SF14 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER A1-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=8472|UniProtKB=Q8NGG8 Q8NGG8 OR8B3 PTHR48018:SF61 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=5300|UniProtKB=P47898 P47898 HTR5A PTHR24247:SF108 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 5A cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=8603|UniProtKB=O43252 O43252 PAPSS1 PTHR11055:SF17 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167 HUMAN|HGNC=5823|UniProtKB=A0A0A0MRZ8 A0A0A0MRZ8 IGKV3D-11 PTHR23267:SF382 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=25605|UniProtKB=Q96HH6 Q96HH6 TMEM19 PTHR13353:SF5 TRANSMEMBRANE PROTEIN 19 TRANSMEMBRANE PROTEIN 19 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=6645|UniProtKB=O43900 O43900 PRICKLE3 PTHR24211:SF19 LIM DOMAIN-CONTAINING PROTEIN PRICKLE PLANAR CELL POLARITY PROTEIN 3 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11079|UniProtKB=Q92581 Q92581 SLC9A6 PTHR10110:SF94 SODIUM/HYDROGEN EXCHANGER SODIUM/HYDROGEN EXCHANGER 6 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=1132|UniProtKB=Q14201 Q14201 BTG3 PTHR22978:SF6 B-CELL TRANSLOCATION GENE PROTEIN BTG3 negative regulation of biological process#GO:0048519;regulation of cell population proliferation#GO:0042127;negative regulation of cell cycle#GO:0045786;nuclear division#GO:0000280;cell cycle process#GO:0022402;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular process#GO:0009987;cell population proliferation#GO:0008283;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;negative regulation of cell population proliferation#GO:0008285;regulation of mitotic cell cycle#GO:0007346;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6997|UniProtKB=Q14814 Q14814 MEF2D PTHR11945:SF23 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2D cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;histone deacetylase binding#GO:0042826;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 MADS box transcription factor#PC00250 CCKR signaling map#P06959>MEF2D#P07048;p38 MAPK pathway#P05918>MEF#P06023;CCKR signaling map#P06959>MEF2#P07032 HUMAN|HGNC=17664|UniProtKB=Q9NQS3 Q9NQS3 NECTIN3 PTHR23277:SF12 NECTIN-RELATED NECTIN-3 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;biological adhesion#GO:0022610 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;apical junction complex#GO:0043296 HUMAN|HGNC=23024|UniProtKB=Q8N668 Q8N668 COMMD1 PTHR21199:SF1 COMM DOMAIN-CONTAINING PROTEIN 1 COMM DOMAIN-CONTAINING PROTEIN 1 inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;regulation of sodium ion transport#GO:0002028;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;regulation of metal ion transport#GO:0010959;positive regulation of cellular metabolic process#GO:0031325;inorganic cation transmembrane transport#GO:0098662;protein catabolic process#GO:0030163;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;positive regulation of protein modification process#GO:0031401;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;copper ion homeostasis#GO:0055070;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of transmembrane transport#GO:0034762;protein modification by small protein conjugation or removal#GO:0070647;transition metal ion homeostasis#GO:0055076;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of transport#GO:0051051;protein localization to cell surface#GO:0034394;cation homeostasis#GO:0055080;regulation of cellular localization#GO:0060341;positive regulation of macromolecule metabolic process#GO:0010604;ion transmembrane transport#GO:0034220;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of ion transmembrane transport#GO:0034765;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;regulation of ion transport#GO:0043269;metal ion homeostasis#GO:0055065;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;ion homeostasis#GO:0050801;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ion transport#GO:0006811;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;regulation of cellular catabolic process#GO:0031329;chemical homeostasis#GO:0048878;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;sodium ion transport#GO:0006814;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;sodium ion transmembrane transport#GO:0035725;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=34024|UniProtKB=Q6ZNK6 Q6ZNK6 TIFAB PTHR31266:SF3 TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A FAMILY MEMBER TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN B response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=8354|UniProtKB=O95007 O95007 OR6B1 PTHR26453:SF284 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6B1 transmembrane signal receptor#PC00197 HUMAN|HGNC=18292|UniProtKB=P0CG37 P0CG37 CFC1 PTHR14949:SF25 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 CRYPTIC FAMILY PROTEIN 1B-RELATED protein binding#GO:0005515;binding#GO:0005488;receptor serine/threonine kinase binding#GO:0033612;signaling receptor binding#GO:0005102 specification of symmetry#GO:0009799;cellular response to stimulus#GO:0051716;heart development#GO:0007507;signal transduction#GO:0007165;circulatory system development#GO:0072359;enzyme linked receptor protein signaling pathway#GO:0007167;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;determination of bilateral symmetry#GO:0009855;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;determination of left/right symmetry#GO:0007368;pattern specification process#GO:0007389;signaling#GO:0023052 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=16884|UniProtKB=Q8N5H7 Q8N5H7 SH2D3C PTHR14247:SF6 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 3C positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of protein modification process#GO:0031401;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=5042|UniProtKB=P55795 P55795 HNRNPH2 PTHR13976:SF33 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=6155|UniProtKB=P05107 P05107 ITGB2 PTHR10082:SF15 INTEGRIN BETA SUBUNIT INTEGRIN BETA-2 amyloid-beta binding#GO:0001540;integrin binding#GO:0005178;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;biological adhesion#GO:0022610;localization of cell#GO:0051674;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052 membrane protein complex#GO:0098796;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;focal adhesion#GO:0005925;integral component of plasma membrane#GO:0005887;cell-substrate junction#GO:0030055;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 HUMAN|HGNC=207|UniProtKB=Q9UKF5 Q9UKF5 ADAM29 PTHR11905:SF34 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 29 developmental process involved in reproduction#GO:0003006;reproductive system development#GO:0061458;system development#GO:0048731;reproduction#GO:0000003;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;sex differentiation#GO:0007548;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;male gonad development#GO:0008584;male sex differentiation#GO:0046661;reproductive structure development#GO:0048608 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=9165|UniProtKB=O43236 O43236 SEPTIN4 PTHR18884:SF71 SEPTIN SEPTIN-4 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 vesicle fusion#GO:0006906;cellular localization#GO:0051641;cell division#GO:0051301;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;cell cycle process#GO:0022402;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;cytoskeleton-dependent cytokinesis#GO:0061640;vesicle organization#GO:0016050;cytokinesis#GO:0000910;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;membrane fission#GO:0090148;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;export from cell#GO:0140352 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell division site#GO:0032153;transport vesicle#GO:0030133;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 HUMAN|HGNC=2530|UniProtKB=P14091 P14091 CTSE PTHR47966:SF26 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CATHEPSIN E endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=25173|UniProtKB=Q96CS4 Q96CS4 ZNF689 PTHR24377:SF695 IP01015P-RELATED ZINC FINGER PROTEIN 689 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24994|UniProtKB=Q9NRY2 Q9NRY2 INIP PTHR31526:SF2 SOSS COMPLEX SUBUNIT C SOSS COMPLEX SUBUNIT C DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25808|UniProtKB=Q3B820 Q3B820 FAM161A PTHR21501:SF3 UNCHARACTERIZED PROTEIN FAM161A cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;organelle#GO:0043226;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=43561|UniProtKB=H3BMG3 H3BMG3 SMKR1 PTHR37932:SF1 SMALL LYSINE-RICH PROTEIN 1 SMALL LYSINE-RICH PROTEIN 1 HUMAN|HGNC=14332|UniProtKB=Q9BXN6 Q9BXN6 SPANXD PTHR23425:SF16 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME A-RELATED HUMAN|HGNC=15547|UniProtKB=Q8IZJ6 Q8IZJ6 TDH PTHR42687:SF1 L-THREONINE 3-DEHYDROGENASE INACTIVE L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 oxidoreductase#PC00176 HUMAN|HGNC=1144|UniProtKB=Q9Y297 Q9Y297 BTRC PTHR19854:SF16 TRANSDUCIN BETA-LIKE 3 F-BOX/WD REPEAT-CONTAINING PROTEIN 1A snoRNA binding#GO:0030515;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;protein modification process#GO:0036211;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;cleavage involved in rRNA processing#GO:0000469;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;endonucleolytic cleavage involved in rRNA processing#GO:0000478;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;SCF ubiquitin ligase complex#GO:0019005;organelle lumen#GO:0043233;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;90S preribosome#GO:0030686 scaffold/adaptor protein#PC00226 Hedgehog signaling pathway#P00025>Slimb#P00683;Wnt signaling pathway#P00057>betaTrCP#P01454 HUMAN|HGNC=6071|UniProtKB=P49441 P49441 INPP1 PTHR43028:SF3 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 INOSITOL POLYPHOSPHATE 1-PHOSPHATASE inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;dephosphorylation#GO:0016311;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphatase#PC00181 HUMAN|HGNC=8974|UniProtKB=Q8NEB9 Q8NEB9 PIK3C3 PTHR10048:SF7 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;phospholipid biosynthetic process#GO:0008654;macroautophagy#GO:0016236;membrane organization#GO:0061024;phosphatidylinositol biosynthetic process#GO:0006661;lipid biosynthetic process#GO:0008610;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;inositol lipid-mediated signaling#GO:0048017;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;organophosphate metabolic process#GO:0019637;autophagy#GO:0006914;phosphatidylinositol phosphorylation#GO:0046854;lipid metabolic process#GO:0006629;signal transduction#GO:0007165;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;process utilizing autophagic mechanism#GO:0061919;glycerolipid metabolic process#GO:0046486;cellular component disassembly#GO:0022411;catabolic process#GO:0009056;phosphatidylinositol-mediated signaling#GO:0048015;vesicle organization#GO:0016050;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound metabolic process#GO:1901564;phosphatidylinositol metabolic process#GO:0046488;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;organelle assembly#GO:0070925;localization#GO:0051179;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;peroxisome organization#GO:0007031 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;phosphatidylinositol 3-kinase complex, class III#GO:0035032;vesicle#GO:0031982;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;endomembrane system#GO:0012505;intracellular#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;Ras Pathway#P04393>PI3K#P04567;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 HUMAN|HGNC=13045|UniProtKB=Q9BRH9 Q9BRH9 ZNF251 PTHR24377:SF421 IP01015P-RELATED ZINC FINGER PROTEIN 251 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26978|UniProtKB=A8K830 A8K830 COLCA2 PTHR36689:SF1 COLORECTAL CANCER-ASSOCIATED PROTEIN 2 COLORECTAL CANCER-ASSOCIATED PROTEIN 2 HUMAN|HGNC=20420|UniProtKB=Q9H714 Q9H714 RUBCNL PTHR45971:SF2 PHOX (PX) DOMAIN-CONTAINING PROTEIN PROTEIN ASSOCIATED WITH UVRAG AS AUTOPHAGY ENHANCER lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 vesicle fusion#GO:0006906;protein-containing complex disassembly#GO:0032984;macroautophagy#GO:0016236;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;catabolic process#GO:0009056;vesicle organization#GO:0016050;autophagosome maturation#GO:0097352;autophagy#GO:0006914;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;whole membrane#GO:0098805 HUMAN|HGNC=25239|UniProtKB=Q6UWY0 Q6UWY0 ARSK PTHR46615:SF1 ARYLSULFATASE K ARYLSULFATASE K HUMAN|HGNC=20469|UniProtKB=Q86YQ2 Q86YQ2 BPIFA4P PTHR47015:SF3 BPI FOLD-CONTAINING FAMILY A MEMBER 1 BPIFA4P PROTEIN-RELATED HUMAN|HGNC=20646|UniProtKB=Q8TAU3 Q8TAU3 ZNF417 PTHR24377:SF655 IP01015P-RELATED ZINC FINGER PROTEIN 417-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25589|UniProtKB=Q9NVA2 Q9NVA2 SEPTIN11 PTHR18884:SF48 SEPTIN SEPTIN-11 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;cell division#GO:0051301;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;cytokinesis#GO:0000910;membrane fission#GO:0090148;vesicle localization#GO:0051648;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;cell cycle#GO:0007049 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 HUMAN|HGNC=1335|UniProtKB=Q9NYF5 Q9NYF5 FAM13B PTHR15904:SF16 FAM13 PROTEIN FAM13B HUMAN|HGNC=11907|UniProtKB=Q9UBN6 Q9UBN6 TNFRSF10D PTHR46330:SF10 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10D positive regulation of apoptotic process#GO:0043065;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TRAIL-R#P00276;p53 pathway#P00059>KILLER/DR5#G01568 HUMAN|HGNC=10630|UniProtKB=P13236 P13236 CCL4 PTHR12015:SF103 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 4-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=18127|UniProtKB=Q96RT7 Q96RT7 TUBGCP6 PTHR19302:SF64 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 6 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;reproductive process#GO:0022414;spindle assembly#GO:0051225;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cytoplasmic microtubule organization#GO:0031122;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;protein polymerization#GO:0051258;organelle fission#GO:0048285;cell cycle#GO:0007049 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;intracellular#GO:0005622;gamma-tubulin complex#GO:0000930;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=20440|UniProtKB=Q5VWZ2 Q5VWZ2 LYPLAL1 PTHR10655:SF66 LYSOPHOSPHOLIPASE-RELATED LYSOPHOSPHOLIPASE-LIKE PROTEIN 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;macromolecule deacylation#GO:0098732;protein deacylation#GO:0035601;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;lipoprotein metabolic process#GO:0042157;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phospholipase#PC00186 HUMAN|HGNC=21666|UniProtKB=Q3MIW9 Q3MIW9 MUCL3 PTHR22094:SF0 DIFFUSE PANBRONCHIOLITIS CRITICAL REGION GENE 1 MUCIN-LIKE PROTEIN 3 HUMAN|HGNC=23326|UniProtKB=Q7Z7A4 Q7Z7A4 PXK PTHR22999:SF23 PX SERINE/THREONINE KINASE PXK PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN HUMAN|HGNC=8351|UniProtKB=Q8NGL0 Q8NGL0 OR5L2 PTHR48018:SF16 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5L2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=19429|UniProtKB=Q8IVJ1 Q8IVJ1 SLC41A1 PTHR16228:SF23 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=11139|UniProtKB=Q9Y6H5 Q9Y6H5 SNCAIP PTHR22882:SF3 SYNPHILIN-1 SYNPHILIN-1 Parkinson disease#P00049>Synphilin#P01225 HUMAN|HGNC=21056|UniProtKB=Q5T6L9 Q5T6L9 ERMARD PTHR31701:SF2 ENDOPLASMIC RETICULUM MEMBRANE-ASSOCIATED RNA DEGRADATION PROTEIN ENDOPLASMIC RETICULUM MEMBRANE-ASSOCIATED RNA DEGRADATION PROTEIN HUMAN|HGNC=12587|UniProtKB=P47985 P47985 UQCRFS1 PTHR10134:SF20 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=208|UniProtKB=Q9UKF2 Q9UKF2 ADAM30 PTHR11905:SF148 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 30 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=10964|UniProtKB=Q96BI1 Q96BI1 SLC22A18 PTHR24002:SF3 SOLUTE CARRIER FAMILY 22 MEMBER 18 SOLUTE CARRIER FAMILY 22 MEMBER 18 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 secondary carrier transporter#PC00258 HUMAN|HGNC=30991|UniProtKB=Q6UXM1 Q6UXM1 LRIG3 PTHR24373:SF311 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS PROTEIN 3 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=49205|UniProtKB=B7ZC32 B7ZC32 KIF28P PTHR24115:SF344 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF28P pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=24943|UniProtKB=Q8TBP5 Q8TBP5 FAM174A PTHR28607:SF1 EXPRESSED PROTEIN MEMBRANE PROTEIN FAM174A HUMAN|HGNC=7696|UniProtKB=O96000 O96000 NDUFB10 PTHR13094:SF1 NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=1186|UniProtKB=Q9NR21 Q9NR21 PARP11 PTHR45740:SF4 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP11 HUMAN|HGNC=5186|UniProtKB=P55345 P55345 PRMT2 PTHR11006:SF92 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 2 protein modifying enzyme#PC00260 HUMAN|HGNC=14903|UniProtKB=Q9BR01 Q9BR01 SULT4A1 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4A1 transferase#PC00220 HUMAN|HGNC=17029|UniProtKB=O95905 O95905 ECD PTHR13060:SF0 SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2 PROTEIN ECDYSONELESS HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=11612|UniProtKB=P23193 P23193 TCEA1 PTHR11477:SF1 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 general transcription factor#PC00259 HUMAN|HGNC=17844|UniProtKB=Q8N4N3 Q8N4N3 KLHL36 PTHR45632:SF4 LD33804P KELCH-LIKE PROTEIN 36 HUMAN|HGNC=31927|UniProtKB=Q9BZX4 Q9BZX4 ROPN1B PTHR14952:SF12 ROPPORIN-1-LIKE PROTEIN ROPPORIN-1B HUMAN|HGNC=28531|UniProtKB=Q2T9J0 Q2T9J0 TYSND1 PTHR21004:SF0 SERINE PROTEASE-RELATED PEROXISOMAL LEADER PEPTIDE-PROCESSING PROTEASE serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;protein metabolic process#GO:0019538;protein processing#GO:0016485;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 serine protease#PC00203 HUMAN|HGNC=13249|UniProtKB=Q6ZSI9 Q6ZSI9 CAPN12 PTHR10183:SF280 CALPAIN CALPAIN-12 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=18073|UniProtKB=Q9P291 Q9P291 ARMCX1 PTHR15712:SF14 ARMADILLO REPEAT CONTAINING PROTEIN ARMADILLO REPEAT-CONTAINING X-LINKED PROTEIN 1 HUMAN|HGNC=3822|UniProtKB=A0A2Z4LIS9 A0A2Z4LIS9 FOXO3B PTHR45767:SF5 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O3B-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19869|UniProtKB=Q96GP6 Q96GP6 SCARF2 PTHR24043:SF5 SCAVENGER RECEPTOR CLASS F SCAVENGER RECEPTOR CLASS F MEMBER 2 membrane traffic protein#PC00150 HUMAN|HGNC=6125|UniProtKB=P35568 P35568 IRS1 PTHR10614:SF11 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 CCKR signaling map#P06959>IRS1#P07106;Gonadotropin-releasing hormone receptor pathway#P06664>IRS-1#P06825;Interleukin signaling pathway#P00036>IRS1/2#P00980;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899;PI3 kinase pathway#P00048>IRS#P01193;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759 HUMAN|HGNC=6881|UniProtKB=P45983 P45983 MAPK8 PTHR24055:SF222 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 8 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;MAPK cascade#GO:0000165;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;JNK cascade#GO:0007254;stress-activated MAPK cascade#GO:0051403;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;stress-activated protein kinase signaling cascade#GO:0031098;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Integrin signalling pathway#P00034>Jnk#P00951;TGF-beta signaling pathway#P00052>JNK#P01284;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>JNK1#P00221;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>JNK1-3#P00545;CCKR signaling map#P06959>MAPK8-10#P07090;FGF signaling pathway#P00021>JNK1-3#P00628;FAS signaling pathway#P00020>JNK#P00615;Oxidative stress response#P00046>JNK1/2#P01129;Ras Pathway#P04393>JNK#P04572;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Apoptosis signaling pathway#P00006>JNK#P00274;Toll receptor signaling pathway#P00054>JNK#P01375;B cell activation#P00010>Jnk#P00402;Parkinson disease#P00049>SAPK#P01219;Gonadotropin-releasing hormone receptor pathway#P06664>JNK1/2#P06847;T cell activation#P00053>Jnk#P01336 HUMAN|HGNC=12627|UniProtKB=Q13107 Q13107 USP4 PTHR21646:SF45 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4 cysteine protease#PC00081 HUMAN|HGNC=17466|UniProtKB=Q8NBI5 Q8NBI5 SLC43A3 PTHR20765:SF1 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 43 MEMBER 3 amino acid transporter#PC00046 HUMAN|HGNC=20093|UniProtKB=Q8N142 Q8N142 ADSS1 PTHR11846:SF2 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 1 ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;AMP metabolic process#GO:0046033;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 HUMAN|HGNC=7658|UniProtKB=Q09161 Q09161 NCBP1 PTHR12412:SF2 CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=18594|UniProtKB=Q969R5 Q969R5 L3MBTL2 PTHR12247:SF64 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 2 protein binding#GO:0005515;methylated histone binding#GO:0035064;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=4501|UniProtKB=O15552 O15552 FFAR2 PTHR45822:SF5 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 2 HUMAN|HGNC=9689|UniProtKB=Q03393 Q03393 PTS PTHR12589:SF7 PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE 6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE HUMAN|HGNC=23049|UniProtKB=Q9NS93 Q9NS93 TM7SF3 PTHR15937:SF3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 HUMAN|HGNC=16918|UniProtKB=O60506 O60506 SYNCRIP PTHR21245:SF11 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN Q RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;negative regulation of cellular catabolic process#GO:0031330;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=1331|UniProtKB=P01031 P01031 C5 PTHR11412:SF83 MACROGLOBULIN / COMPLEMENT COMPLEMENT C5 protease inhibitor#PC00191 HUMAN|HGNC=30550|UniProtKB=O60337 O60337 MARCHF6 PTHR13145:SF0 SSM4 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MARCHF6 cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9982|UniProtKB=P22670 P22670 RFX1 PTHR12619:SF23 RFX TRANSCRIPTION FACTOR FAMILY MHC CLASS II REGULATORY FACTOR RFX1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=23242|UniProtKB=Q8IUC8 Q8IUC8 GALNT13 PTHR11675:SF47 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 13 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=6569|UniProtKB=O00214 O00214 LGALS8 PTHR11346:SF22 GALECTIN GALECTIN-8 extracellular matrix protein#PC00102 HUMAN|HGNC=32949|UniProtKB=Q9NXE4 Q9NXE4 SMPD4 PTHR12988:SF6 SPHINGOMYELIN PHOSPHODIESTERASE 4 SPHINGOMYELIN PHOSPHODIESTERASE 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;organonitrogen compound catabolic process#GO:1901565;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;sphingolipid biosynthetic process#GO:0030148;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;glycerolipid catabolic process#GO:0046503;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;ceramide metabolic process#GO:0006672;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;ceramide biosynthetic process#GO:0046513;phospholipid catabolic process#GO:0009395;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cellular amide metabolic process#GO:0043603 phosphodiesterase#PC00185 HUMAN|HGNC=3358|UniProtKB=O14638 O14638 ENPP3 PTHR10151:SF107 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 3 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphate diphosphatase activity#GO:0047429;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;cellular metabolic process#GO:0044237;nucleoside triphosphate catabolic process#GO:0009143;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 HUMAN|HGNC=29834|UniProtKB=Q8WUS8 Q8WUS8 SDR42E1 PTHR10366:SF355 NAD DEPENDENT EPIMERASE/DEHYDRATASE SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 42E MEMBER 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091 HUMAN|HGNC=3493|UniProtKB=P43268 P43268 ETV4 PTHR11849:SF181 ETS ETS TRANSLOCATION VARIANT 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=30391|UniProtKB=Q9UG01 Q9UG01 IFT172 PTHR15722:SF2 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 172 HOMOLOG microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 structural protein#PC00211 HUMAN|HGNC=18391|UniProtKB=Q96PL1 Q96PL1 SCGB3A2 PTHR34829:SF2 SECRETOGLOBIN FAMILY 3A MEMBER 2 SECRETOGLOBIN FAMILY 3A MEMBER 2 HUMAN|HGNC=19232|UniProtKB=Q6UXB2 Q6UXB2 CXCL17 PTHR37351:SF1 C-X-C MOTIF CHEMOKINE 17 C-X-C MOTIF CHEMOKINE 17 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein metabolic process#GO:0051246;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of localization#GO:0032879;positive regulation of protein modification process#GO:0031401;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of cell migration#GO:0030334;regulation of MAP kinase activity#GO:0043405;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of defense response#GO:0031347;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;taxis#GO:0042330;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;cytokine production#GO:0001816;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of leukocyte migration#GO:0002687;positive regulation of transferase activity#GO:0051347;regulation of chemotaxis#GO:0050920;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;myeloid leukocyte migration#GO:0097529;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;negative regulation of response to stimulus#GO:0048585;positive regulation of catalytic activity#GO:0043085;positive regulation of immune system process#GO:0002684;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;cell chemotaxis#GO:0060326;regulation of inflammatory response#GO:0050727;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;positive regulation of kinase activity#GO:0033674;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;negative regulation of inflammatory response#GO:0050728;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component movement#GO:0051272;regulation of phosphorus metabolic process#GO:0051174;leukocyte migration#GO:0050900;granulocyte migration#GO:0097530;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;macrophage chemotaxis#GO:0048246;macromolecule metabolic process#GO:0043170;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;movement of cell or subcellular component#GO:0006928;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;positive regulation of MAP kinase activity#GO:0043406;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;granulocyte chemotaxis#GO:0071621;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of leukocyte chemotaxis#GO:0002690;cell migration#GO:0016477;regulation of transferase activity#GO:0051338 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=2460|UniProtKB=P67870 P67870 CSNK2B PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase modulator#PC00140 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 HUMAN|HGNC=1248|UniProtKB=P06681 P06681 C2 PTHR46393:SF2 SUSHI DOMAIN-CONTAINING PROTEIN COMPLEMENT C2 HUMAN|HGNC=17277|UniProtKB=Q96KR1 Q96KR1 ZFR PTHR45762:SF3 ZINC FINGER RNA-BINDING PROTEIN ZINC FINGER RNA-BINDING PROTEIN nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=8642|UniProtKB=Q96JT2 Q96JT2 SLC45A3 PTHR19432:SF37 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;solute:cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=32583|UniProtKB=Q6UB28 Q6UB28 METAP1D PTHR43330:SF8 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1D, MITOCHONDRIAL metalloprotease#PC00153 HUMAN|HGNC=3785|UniProtKB=P49356 P49356 FNTB PTHR11774:SF6 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA acyltransferase#PC00042 HUMAN|HGNC=17795|UniProtKB=Q9H4B6 Q9H4B6 SAV1 PTHR10316:SF73 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED PROTEIN SALVADOR HOMOLOG 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=5581|UniProtKB=P01766 P01766 IGHV3-13 PTHR23266:SF277 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-13 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=1148|UniProtKB=O43683 O43683 BUB1 PTHR14030:SF4 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;catalytic activity#GO:0003824;protein kinase activity#GO:0004672 negative regulation of sister chromatid segregation#GO:0033046;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of mitotic sister chromatid segregation#GO:0033047;reproductive process#GO:0022414;negative regulation of cellular component organization#GO:0051129;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;mitotic cell cycle phase transition#GO:0044772;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;meiotic sister chromatid segregation#GO:0045144;mitotic cell cycle process#GO:1903047;sister chromatid cohesion#GO:0007062;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;mitotic spindle assembly checkpoint#GO:0007094;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;mitotic cell cycle checkpoint#GO:0007093;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;metaphase/anaphase transition of cell cycle#GO:0044784;negative regulation of chromosome separation#GO:1905819;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome kinetochore#GO:0000777;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;condensed nuclear chromosome kinetochore#GO:0000778;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=34498|UniProtKB=B1ATL7 B1ATL7 PRR32 PTHR37343:SF1 PROLINE-RICH PROTEIN 32 PROLINE-RICH PROTEIN 32 HUMAN|HGNC=8246|UniProtKB=Q13607 Q13607 OR2F1 PTHR26453:SF116 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2F1 transmembrane signal receptor#PC00197 HUMAN|HGNC=7604|UniProtKB=Q9NQX4 Q9NQX4 MYO5C PTHR13140:SF313 MYOSIN UNCONVENTIONAL MYOSIN-VC pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=542|UniProtKB=P09525 P09525 ANXA4 PTHR10502:SF28 ANNEXIN ANNEXIN A4 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calcium-binding protein#PC00060 HUMAN|HGNC=28464|UniProtKB=A0PJW6 A0PJW6 TMEM223 PTHR14549:SF2 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 223 HUMAN|HGNC=25042|UniProtKB=Q9NT99 Q9NT99 LRRC4B PTHR24369:SF102 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B HUMAN|HGNC=22943|UniProtKB=Q96MN2 Q96MN2 NLRP4 PTHR45690:SF6 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 4 HUMAN|HGNC=5739|UniProtKB=A0A075B6S9 A0A075B6S9 IGKV1-37 PTHR23267:SF468 IMMUNOGLOBULIN LIGHT CHAIN NON-FUNCTIONAL IMMUNOGLOBULINN KAPPA VARIABLE 1-37-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=10288|UniProtKB=Q8TA86 Q8TA86 RP9 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;rough endoplasmic reticulum#GO:0005791;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=24930|UniProtKB=Q96HP8 Q96HP8 TMEM176A PTHR15756:SF6 LR8/HCA112 TRANSMEMBRANE PROTEIN 176A HUMAN|HGNC=14888|UniProtKB=O75190 O75190 DNAJB6 PTHR43948:SF6 FAMILY NOT NAMED DNAJ HOMOLOG SUBFAMILY B MEMBER 6 HUMAN|HGNC=17184|UniProtKB=Q96DX5 Q96DX5 ASB9 PTHR24136:SF17 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 9 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222 HUMAN|HGNC=11586|UniProtKB=Q9Y4P3 Q9Y4P3 TBL2 PTHR44321:SF1 TRANSDUCIN BETA-LIKE PROTEIN 2 TRANSDUCIN BETA-LIKE PROTEIN 2 HUMAN|HGNC=3330|UniProtKB=O00423 O00423 EML1 PTHR13720:SF22 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819 HUMAN|HGNC=48327|UniProtKB=H3BUK9 H3BUK9 POTEB2 PTHR24118:SF65 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER B-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=10575|UniProtKB=P13521 P13521 SCG2 PTHR15119:SF0 SECRETOGRANIN II SECRETOGRANIN-2 Gonadotropin-releasing hormone receptor pathway#P06664>Scg2#G06880 HUMAN|HGNC=30842|UniProtKB=Q7Z3Y7 Q7Z3Y7 KRT28 PTHR23239:SF215 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 28 HUMAN|HGNC=13639|UniProtKB=O95231 O95231 VENTX PTHR24327:SF29 HOMEOBOX PROTEIN HOMEOBOX PROTEIN VENTX cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=29303|UniProtKB=Q9P1Z9 Q9P1Z9 CCDC180 PTHR21444:SF14 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 COILED-COIL DOMAIN-CONTAINING PROTEIN 180 HUMAN|HGNC=2046|UniProtKB=O14493 O14493 CLDN4 PTHR12002:SF89 CLAUDIN CLAUDIN-4 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=7750|UniProtKB=Q92832 Q92832 NELL1 PTHR24042:SF2 NEL HOMOLOG PROTEIN KINASE C-BINDING PROTEIN NELL1 calcium-binding protein#PC00060 HUMAN|HGNC=32696|UniProtKB=A8MYV0 A8MYV0 DCDC2C PTHR23004:SF9 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2C supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;cortical cytoskeleton#GO:0030863;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;cortical actin cytoskeleton#GO:0030864;supramolecular fiber#GO:0099512;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874 HUMAN|HGNC=13622|UniProtKB=Q9GZN6 Q9GZN6 SLC6A16 PTHR11616:SF233 SODIUM/CHLORIDE DEPENDENT TRANSPORTER ORPHAN SODIUM- AND CHLORIDE-DEPENDENT NEUROTRANSMITTER TRANSPORTER NTT5 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 HUMAN|HGNC=44317|UniProtKB=Q96I23 Q96I23 PYURF PTHR33505:SF7 ZGC:162634 PROTEIN PREY, MITOCHONDRIAL lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=8473|UniProtKB=Q96RC9 Q96RC9 OR8B4 PTHR48018:SF14 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=16703|UniProtKB=Q9P2U8 Q9P2U8 SLC17A6 PTHR11662:SF201 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;L-glutamate transmembrane transporter activity#GO:0005313;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;ion transport#GO:0006811;transport#GO:0006810;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;regulation of synapse structure or activity#GO:0050803;synaptic transmission, glutamatergic#GO:0035249;signaling#GO:0023052;cell-cell signaling#GO:0007267;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;transport vesicle membrane#GO:0030658;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 Ionotropic glutamate receptor pathway#P00037>Vglut#P01021 HUMAN|HGNC=2339|UniProtKB=P29373 P29373 CRABP2 PTHR11955:SF135 FATTY ACID BINDING PROTEIN CELLULAR RETINOIC ACID-BINDING PROTEIN 2 HUMAN|HGNC=11009|UniProtKB=P14672 P14672 SLC2A4 PTHR23503:SF120 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 4 HUMAN|HGNC=9052|UniProtKB=P00749 P00749 PLAU PTHR24264:SF38 TRYPSIN-RELATED UROKINASE-TYPE PLASMINOGEN ACTIVATOR serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;cell adhesion mediated by integrin#GO:0033627;biological adhesion#GO:0022610;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cell adhesion#GO:0007155;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;regulation of cell adhesion#GO:0030155;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 CCKR signaling map#P06959>uPA#G06974;Plasminogen activating cascade#P00050>uPA#P01243;Blood coagulation#P00011>uPA#P00424;CCKR signaling map#P06959>uPA#G07267;Plasminogen activating cascade#P00050>pro-uPA#P01262;CCKR signaling map#P06959>uPA#P07039;Blood coagulation#P00011>uPAR#P00433 HUMAN|HGNC=28757|UniProtKB=Q6UWV7 Q6UWV7 SHISAL2A PTHR31395:SF3 SHISA PROTEIN SHISA-LIKE-2A scaffold/adaptor protein#PC00226 HUMAN|HGNC=23366|UniProtKB=Q9BPX5 Q9BPX5 ARPC5L PTHR12644:SF2 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 5-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;localization of cell#GO:0051674;actin polymerization or depolymerization#GO:0008154;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Huntington disease#P00029>Arp2/3 complex#P00811 HUMAN|HGNC=31110|UniProtKB=Q4LDR2 Q4LDR2 CTXN3 PTHR16736:SF1 CORTEXIN-1-RELATED CORTEXIN-3 HUMAN|HGNC=20533|UniProtKB=P60413 P60413 KRTAP10-12 PTHR23262:SF50 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-12 HUMAN|HGNC=11252|UniProtKB=Q9HCB6 Q9HCB6 SPON1 PTHR11311:SF16 SPONDIN SPONDIN-1 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cell adhesion molecule#PC00069 HUMAN|HGNC=33825|UniProtKB=Q6IE38 Q6IE38 SPINK14 PTHR47499:SF3 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 SERINE PROTEASE INHIBITOR KAZAL-TYPE 14 protease inhibitor#PC00191 HUMAN|HGNC=9786|UniProtKB=P20340 P20340 RAB6A PTHR24073:SF1089 DRAB5-RELATED RAS-RELATED PROTEIN RAB-6A-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|Ensembl=ENSG00000196589|UniProtKB=A0A1B0GVZ6 A0A1B0GVZ6 MBD3L2B PTHR12396:SF6 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 3-LIKE 2-RELATED HUMAN|HGNC=33237|UniProtKB=Q4G0W2 Q4G0W2 DUSP28 PTHR45961:SF7 IP21249P DUAL SPECIFICITY PHOSPHATASE 28 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=33164|UniProtKB=Q6NXT2 Q6NXT2 H3-5 PTHR11426:SF228 HISTONE H3 HISTONE H3.3-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 histone#PC00118 DNA replication#P00017>Histones#P00527 HUMAN|HGNC=12652|UniProtKB=P50552 P50552 VASP PTHR11202:SF12 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER VASODILATOR-STIMULATED PHOSPHOPROTEIN protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;tube morphogenesis#GO:0035239;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of organelle organization#GO:0033043;tube development#GO:0035295;cellular component organization#GO:0016043;positive regulation of cellular process#GO:0048522;chordate embryonic development#GO:0043009;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;embryo development#GO:0009790;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;embryo development ending in birth or egg hatching#GO:0009792;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;epithelium development#GO:0060429;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;cell projection morphogenesis#GO:0048858;system development#GO:0048731;cell differentiation#GO:0030154;regulation of protein-containing complex assembly#GO:0043254;axon guidance#GO:0007411;supramolecular fiber organization#GO:0097435;neuron differentiation#GO:0030182;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;regulation of protein polymerization#GO:0032271;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;neural tube development#GO:0021915;cell morphogenesis involved in differentiation#GO:0000904;regulation of actin filament length#GO:0030832;multicellular organism development#GO:0007275;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cell morphogenesis#GO:0000902;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;positive regulation of protein-containing complex assembly#GO:0031334;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;tissue morphogenesis#GO:0048729;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;morphogenesis of an epithelium#GO:0002009;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036;embryonic morphogenesis#GO:0048598 scaffold/adaptor protein#PC00226 Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516;Integrin signalling pathway#P00034>VASP#P00934;Axon guidance mediated by netrin#P00009>Ena#P00361 HUMAN|HGNC=24603|UniProtKB=Q5H9I0 Q5H9I0 TFDP3 PTHR12548:SF13 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP FAMILY MEMBER 3 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=28904|UniProtKB=Q9BQI0 Q9BQI0 AIF1L PTHR10356:SF5 ALLOGRAFT INFLAMMATORY FACTOR-1 ALLOGRAFT INFLAMMATORY FACTOR 1-LIKE cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;actin filament binding#GO:0051015;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ion binding#GO:0043167;actin binding#GO:0003779 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;plasma membrane bounded cell projection assembly#GO:0120031 supramolecular complex#GO:0099080;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;ruffle membrane#GO:0032587;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;ruffle#GO:0001726;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 calmodulin-related#PC00061 HUMAN|HGNC=14576|UniProtKB=O15068 O15068 MCF2L PTHR22826:SF115 RHO GUANINE EXCHANGE FACTOR-RELATED GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=12436|UniProtKB=O43396 O43396 TXNL1 PTHR46115:SF1 THIOREDOXIN-LIKE PROTEIN 1 THIOREDOXIN-LIKE PROTEIN 1 oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 HUMAN|HGNC=33788|UniProtKB=Q6NUJ2 Q6NUJ2 C11orf87 PTHR31870:SF2 SI:DKEY-183I3.9-RELATED SI:DKEY-183I3.9-RELATED HUMAN|HGNC=8686|UniProtKB=Q9Y5E8 Q9Y5E8 PCDHB15 PTHR24028:SF97 CADHERIN-87A PROTOCADHERIN BETA-15 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=8948|UniProtKB=P29622 P29622 SERPINA4 PTHR11461:SF194 SERINE PROTEASE INHIBITOR, SERPIN KALLISTATIN serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=24513|UniProtKB=Q5VZI3 Q5VZI3 TMEM268 PTHR31193:SF1 TRANSMEMBRANE PROTEIN C9ORF91 TRANSMEMBRANE PROTEIN 268 HUMAN|HGNC=5|UniProtKB=P04217 P04217 A1BG PTHR11738:SF184 MHC CLASS I NK CELL RECEPTOR ALPHA-1B-GLYCOPROTEIN immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=10935|UniProtKB=Q05940 Q05940 SLC18A2 PTHR23506:SF30 FAMILY NOT NAMED SYNAPTIC VESICULAR AMINE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;symporter activity#GO:0015293;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;sodium:chloride symporter activity#GO:0015378;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;metal ion transmembrane transporter activity#GO:0046873;monoamine transmembrane transporter activity#GO:0008504;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;neurotransmitter transport#GO:0006836;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;terminal bouton#GO:0043195;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 Nicotine pharmacodynamics pathway#P06587>SLC18A2#P06604;Dopamine receptor mediated signaling pathway#P05912>VAT2#P05960;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424;5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;Adrenaline and noradrenaline biosynthesis#P00001>VAT2#P00070;5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410;Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071;CCKR signaling map#P06959>VMAT2#G07295;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418;CCKR signaling map#P06959>VMAT2#P07137;CCKR signaling map#P06959>VMAT2#G07002 HUMAN|HGNC=29260|UniProtKB=Q6PIU2 Q6PIU2 NCEH1 PTHR23024:SF108 ARYLACETAMIDE DEACETYLASE NEUTRAL CHOLESTEROL ESTER HYDROLASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 deacetylase#PC00087 HUMAN|HGNC=23999|UniProtKB=Q9P0I2 Q9P0I2 EMC3 PTHR13116:SF5 UNCHARACTERIZED ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 cellular process#GO:0009987;protein folding#GO:0006457 membrane protein complex#GO:0098796;ER membrane protein complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=14326|UniProtKB=Q9BXJ4 Q9BXJ4 C1QTNF3 PTHR22923:SF62 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 3 HUMAN|HGNC=3288|UniProtKB=Q13541 Q13541 EIF4EBP1 PTHR12669:SF14 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1 protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;regulation of translational initiation#GO:0006446;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;translational initiation#GO:0006413;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 p53 pathway by glucose deprivation#P04397>4E-BP1#P04637;CCKR signaling map#P06959>4E-BP1#P07230;p38 MAPK pathway#P05918>4E-BP1#P06042 HUMAN|Ensembl=ENSG00000284691|UniProtKB=B7ZLF3 B7ZLF3 LOC402624 PTHR24390:SF144 ZINC FINGER PROTEIN EXPRESSED SEQUENCE AI854703 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=33146|UniProtKB=Q6ZMV5 Q6ZMV5 PPP4R3C PTHR23318:SF19 ATP SYNTHASE GAMMA-RELATED PROTEIN PPP4R3C ATP synthase#PC00002 HUMAN|HGNC=3244|UniProtKB=Q9NZN3 Q9NZN3 EHD3 PTHR11216:SF67 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 3 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 microtubule-based protein transport#GO:0099118;endosomal transport#GO:0016197;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;endocytic recycling#GO:0032456;membrane invagination#GO:0010324;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;protein localization to plasma membrane#GO:0072659;vesicle localization#GO:0051648;protein localization to membrane#GO:0072657;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;protein localization to cell periphery#GO:1990778;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;perinuclear region of cytoplasm#GO:0048471;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=29853|UniProtKB=Q9P2P5 Q9P2P5 HECW2 PTHR11254:SF127 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HECW2 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=4468|UniProtKB=Q9UKP6 Q9UKP6 UTS2R PTHR24230:SF60 G-PROTEIN COUPLED RECEPTOR UROTENSIN-2 RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=23|UniProtKB=P80404 P80404 ABAT PTHR43206:SF1 AMINOTRANSFERASE 4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;transaminase activity#GO:0008483;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transaminase#PC00216 Aminobutyrate degradation#P02726>4-aminobutyrate aminotransferase#P02825;Pyrimidine Metabolism#P02771>Aminotransferase#P03129;Gamma-aminobutyric acid synthesis#P04384>GABA aminotransferase#P04480 HUMAN|HGNC=27310|UniProtKB=Q8NFG4 Q8NFG4 FLCN PTHR31441:SF2 FOLLICULIN FAMILY MEMBER FOLLICULIN signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of molecular function#GO:0065009;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;regulation of hydrolase activity#GO:0051336;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;TOR signaling#GO:0031929;regulation of cell communication#GO:0010646;TORC1 signaling#GO:0038202;cellular response to stimulus#GO:0051716;positive regulation of GTPase activity#GO:0043547;positive regulation of catalytic activity#GO:0043085;regulation of GTPase activity#GO:0043087;cell communication#GO:0007154;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=6230|UniProtKB=O43448 O43448 KCNAB3 PTHR43150:SF3 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;protein binding#GO:0005515;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of metal ion transport#GO:0010959;ion transport#GO:0006811;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;metabolic process#GO:0008152;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 HUMAN|HGNC=594|UniProtKB=Q9BZZ5 Q9BZZ5 API5 PTHR12758:SF23 APOPTOSIS INHIBITOR 5-RELATED APOPTOSIS INHIBITOR 5 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=3677|UniProtKB=Q9NP95 Q9NP95 FGF20 PTHR11486:SF72 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 20 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=8851|UniProtKB=O60683 O60683 PEX10 PTHR23350:SF0 PEROXISOME ASSEMBLY PROTEIN 10 PEROXISOME BIOGENESIS FACTOR 10 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein targeting to peroxisome#GO:0006625;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein localization to peroxisome#GO:0072662;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;microbody membrane#GO:0031903;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 chaperone#PC00072 HUMAN|HGNC=18443|UniProtKB=Q7Z3Z3 Q7Z3Z3 PIWIL3 PTHR22891:SF41 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 3 translation initiation factor#PC00224 HUMAN|HGNC=27146|UniProtKB=Q5TA31 Q5TA31 RNF187 PTHR24103:SF564 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE RNF187-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;innate immune response#GO:0045087;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of molecular function#GO:0044092;negative regulation of DNA-binding transcription factor activity#GO:0043433 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=11017|UniProtKB=O15432 O15432 SLC31A2 PTHR12483:SF8 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS LOW AFFINITY COPPER UPTAKE PROTEIN 2-RELATED secondary carrier transporter#PC00258 HUMAN|HGNC=3280|UniProtKB=P55884 P55884 EIF3B PTHR14068:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=14429|UniProtKB=Q9Y5L5 Q9Y5L5 LENEP PTHR16968:SF2 LENS EPITHELIAL CELL PROTEIN LEP503 LENS EPITHELIAL CELL PROTEIN LEP503 HUMAN|HGNC=14257|UniProtKB=Q8N6Y1 Q8N6Y1 PCDH20 PTHR24028:SF260 CADHERIN-87A PROTOCADHERIN-20 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=12113|UniProtKB=A0A0B4J275 A0A0B4J275 TRAV17 PTHR19433:SF85 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 17 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=28207|UniProtKB=Q86VX9 Q86VX9 MON1A PTHR13027:SF14 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG A HUMAN|HGNC=24733|UniProtKB=A2VDF0 A2VDF0 FUOM PTHR31690:SF4 FUCOSE MUTAROTASE FUCOSE MUTAROTASE carbohydrate binding#GO:0030246;isomerase activity#GO:0016853;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;glycosylation#GO:0070085;organic substance metabolic process#GO:0071704 HUMAN|HGNC=2444|UniProtKB=P41240 P41240 CSK PTHR24418:SF407 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE CSK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;regulation of cell communication#GO:0010646;cell-cell junction organization#GO:0045216;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;immune response#GO:0006955;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;cell junction organization#GO:0034330;biological regulation#GO:0065007;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of biological process#GO:0048518;signaling#GO:0023052 Integrin signalling pathway#P00034>Csk#P00913;Parkinson disease#P00049>Src kinase#P01230;CCKR signaling map#P06959>CSK#P07072;T cell activation#P00053>Csk#P01304 HUMAN|HGNC=9852|UniProtKB=O95373 O95373 IPO7 PTHR10997:SF27 IMPORTIN-7, 8, 11 IMPORTIN-7 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=28331|UniProtKB=Q8WW62 Q8WW62 TMED6 PTHR22811:SF45 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 6 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=14868|UniProtKB=O95236 O95236 APOL3 PTHR14096:SF40 APOLIPOPROTEIN L APOLIPOPROTEIN L3 lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052 HUMAN|HGNC=13707|UniProtKB=Q8WXD2 Q8WXD2 SCG3 PTHR17388:SF2 SECRETOGRANIN III SECRETOGRANIN-3 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=44160|UniProtKB=A6NCL2 A6NCL2 LRCOL1 PTHR10041:SF6 COLIPASE LEUCINE-RICH COLIPASE-LIKE PROTEIN 1 protein-binding activity modulator#PC00095 HUMAN|HGNC=33718|UniProtKB=Q8TD35 Q8TD35 LKAAEAR1 PTHR35665:SF1 PROTEIN LKAAEAR1 PROTEIN LKAAEAR1 HUMAN|HGNC=2171|UniProtKB=Q12860 Q12860 CNTN1 PTHR44170:SF10 PROTEIN SIDEKICK CONTACTIN-1 HUMAN|HGNC=30599|UniProtKB=Q96CF2 Q96CF2 CHMP4C PTHR22761:SF77 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4C endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;leaflet of membrane bilayer#GO:0097478;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562 membrane traffic protein#PC00150 HUMAN|HGNC=548|UniProtKB=P28039 P28039 AOAH PTHR15010:SF0 ACYLOXYACYL HYDROLASE ACYLOXYACYL HYDROLASE cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;negative regulation of biological process#GO:0048519;cellular macromolecule metabolic process#GO:0044260;negative regulation of inflammatory response#GO:0050728;lipid catabolic process#GO:0016042;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;defense response#GO:0006952;cellular lipid catabolic process#GO:0044242;carbohydrate metabolic process#GO:0005975;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;polysaccharide metabolic process#GO:0005976;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular carbohydrate metabolic process#GO:0044262;regulation of defense response#GO:0031347;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;cellular lipid metabolic process#GO:0044255;cellular polysaccharide metabolic process#GO:0044264 hydrolase#PC00121 HUMAN|HGNC=23480|UniProtKB=P85037 P85037 FOXK1 PTHR45881:SF4 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED FORKHEAD BOX PROTEIN K1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=19857|UniProtKB=Q86U28 Q86U28 ISCA2 PTHR43011:SF1 IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL cation binding#GO:0043169;4 iron, 4 sulfur cluster binding#GO:0051539;metal cluster binding#GO:0051540;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=24280|UniProtKB=A8MW92 A8MW92 PHF20L1 PTHR15856:SF26 PHD FINGER PROTEIN 20-RELATED PHD FINGER PROTEIN 20-LIKE PROTEIN 1 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;histone acetylation#GO:0016573;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;peptidyl-lysine modification#GO:0018205;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=13917|UniProtKB=Q13838 Q13838 DDX39B PTHR47958:SF124 ATP-DEPENDENT RNA HELICASE DBP3 SPLICEOSOME RNA HELICASE DDX39B catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;RNA metabolic process#GO:0016070;transport#GO:0006810;RNA processing#GO:0006396;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;heterocycle metabolic process#GO:0046483;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;peptide transport#GO:0015833;mRNA transport#GO:0051028;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;mRNA processing#GO:0006397;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA splicing, via transesterification reactions#GO:0000375;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 HUMAN|HGNC=3766|UniProtKB=P49771 P49771 FLT3LG PTHR11032:SF1 SL CYTOKINE FMS-RELATED TYROSINE KINASE 3 LIGAND binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=27272|UniProtKB=Q5JUX0 Q5JUX0 SPIN3 PTHR10405:SF18 SPINDLIN SPINDLIN-3 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=30369|UniProtKB=Q9NXZ1 Q9NXZ1 SAGE1 PTHR12957:SF36 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED SAGE1-LIKE PROTEIN-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 RNA helicase#PC00032 HUMAN|Gene=SELM|UniProtKB=Q8WWX9 Q8WWX9 SELENOM PTHR13077:SF7 SELENOPROTEIN F SELENOPROTEIN M catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=9970|UniProtKB=P35250 P35250 RFC2 PTHR11669:SF5 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 2 pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 HUMAN|HGNC=11191|UniProtKB=P35716 P35716 SOX11 PTHR10270:SF113 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-11 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=3275|UniProtKB=O00303 O00303 EIF3F PTHR10540:SF16 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=8481|UniProtKB=Q8WZ84 Q8WZ84 OR8D1 PTHR48018:SF72 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=16135|UniProtKB=Q8N6M3 Q8N6M3 FITM2 PTHR23129:SF1 UNCHARACTERIZED FAT STORAGE-INDUCING TRANSMEMBRANE PROTEIN 2 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;maintenance of location#GO:0051235;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;lipid localization#GO:0010876;lipid storage#GO:0019915;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=30239|UniProtKB=Q9H1C7 Q9H1C7 CYSTM1 PTHR47564:SF1 CYSTEINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 CYSTEINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 HUMAN|HGNC=30236|UniProtKB=O14804 O14804 TAAR5 PTHR24249:SF307 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 5 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=31991|UniProtKB=P0DPF3 P0DPF3 NBPF9 PTHR14199:SF35 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 10-RELATED HUMAN|HGNC=29014|UniProtKB=O15060 O15060 ZBTB39 PTHR24399:SF34 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 39 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=8516|UniProtKB=Q6ZRI0 Q6ZRI0 OTOG PTHR11339:SF228 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED OTOGELIN extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=7800|UniProtKB=Q9UBC1 Q9UBC1 NFKBIL1 PTHR15263:SF1 I-KAPPA-B-LIKE PROTEIN IKBL NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1 protein-binding activity modulator#PC00095 B cell activation#P00010>I kappa B#P00392 HUMAN|HGNC=25309|UniProtKB=Q6P2H3 Q6P2H3 CEP85 PTHR31075:SF3 FAMILY NOT NAMED CENTROSOMAL PROTEIN OF 85 KDA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=18368|UniProtKB=Q9UM07 Q9UM07 PADI4 PTHR10837:SF3 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE TYPE-4 HUMAN|HGNC=42540|UniProtKB=A8MVZ5 A8MVZ5 BTNL10 PTHR24100:SF133 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 10 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=936|UniProtKB=Q92934 Q92934 BAD PTHR28540:SF1 BCL2-ASSOCIATED AGONIST OF CELL DEATH BCL2-ASSOCIATED AGONIST OF CELL DEATH CCKR signaling map#P06959>BAD#P07210 HUMAN|HGNC=8594|UniProtKB=O75781 O75781 PALM PTHR10498:SF6 PARALEMMIN-RELATED PARALEMMIN-1 HUMAN|HGNC=2300|UniProtKB=Q96IY4 Q96IY4 CPB2 PTHR11705:SF17 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE B2 hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824 negative regulation of biological process#GO:0048519;regulation of coagulation#GO:0050818;wound healing#GO:0042060;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;regulation of wound healing#GO:0061041;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of coagulation#GO:0050819;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;regulation of body fluid levels#GO:0050878;hemostasis#GO:0007599;coagulation#GO:0050817;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of response to wounding#GO:1903034;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;negative regulation of blood coagulation#GO:0030195;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153 Plasminogen activating cascade#P00050>TAFI#P01247 HUMAN|HGNC=19319|UniProtKB=Q9UGN4 Q9UGN4 CD300A PTHR11860:SF99 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 8 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=3578|UniProtKB=Q9UNN5 Q9UNN5 FAF1 PTHR23322:SF56 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 1 FAS signaling pathway#P00020>FAF1#P00609 HUMAN|HGNC=16469|UniProtKB=Q15057 Q15057 ACAP2 PTHR23180:SF241 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=24240|UniProtKB=Q99999 Q99999 GAL3ST1 PTHR14647:SF56 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;developmental process#GO:0032502;glycolipid metabolic process#GO:0006664;biosynthetic process#GO:0009058;nervous system development#GO:0007399;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;multicellular organism development#GO:0007275;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;anatomical structure development#GO:0048856;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;multicellular organismal process#GO:0032501;cellular lipid metabolic process#GO:0044255;cellular amide metabolic process#GO:0043603;myelination#GO:0042552 transferase#PC00220 HUMAN|HGNC=18831|UniProtKB=Q96CG8 Q96CG8 CTHRC1 PTHR11903:SF18 PROSTAGLANDIN G/H SYNTHASE COLLAGEN TRIPLE HELIX REPEAT-CONTAINING PROTEIN 1 oxygenase#PC00177 HUMAN|HGNC=8097|UniProtKB=Q9UMX2 Q9UMX2 OAZ3 PTHR10279:SF9 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 3 carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;ornithine decarboxylase activity#GO:0004586;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular function regulator#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule catabolic process#GO:0009057;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;positive regulation of protein catabolic process#GO:0045732;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=34430|UniProtKB=A1IGU5 A1IGU5 ARHGEF37 PTHR22834:SF9 NUCLEAR FUSION PROTEIN FUS2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 37 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 HUMAN|HGNC=15923|UniProtKB=Q14498 Q14498 RBM39 PTHR23139:SF112 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 39 HUMAN|HGNC=11910|UniProtKB=Q93038 Q93038 TNFRSF25 PTHR47220:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 25 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 25 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=3126|UniProtKB=Q9UH73 Q9UH73 EBF1 PTHR10747:SF26 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=11037|UniProtKB=P31639 P31639 SLC5A2 PTHR11819:SF145 SOLUTE CARRIER FAMILY 5 SODIUM/GLUCOSE COTRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sugar transmembrane transporter activity#GO:0051119;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=9341|UniProtKB=O43663 O43663 PRC1 PTHR19321:SF1 PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED PROTEIN REGULATOR OF CYTOKINESIS 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;cell division#GO:0051301;mitotic spindle organization#GO:0007052;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;mitotic spindle assembly#GO:0090307;cytoskeleton-dependent cytokinesis#GO:0061640;spindle assembly#GO:0051225;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;cytokinesis#GO:0000910;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;membrane fission#GO:0090148;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;organelle organization#GO:0006996;organelle fission#GO:0048285;cell cycle#GO:0007049 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;spindle midzone#GO:0051233;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;mitotic spindle midzone#GO:1990023;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=14178|UniProtKB=Q96QI5 Q96QI5 HS3ST6 PTHR10605:SF62 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 6 transferase#PC00220 HUMAN|HGNC=13422|UniProtKB=Q9NZH4 Q9NZH4 PTTG3P PTHR10418:SF3 SECURIN-3 PITUITARY TUMOR-TRANSFORMING GENE 3 PROTEIN-RELATED negative regulation of sister chromatid segregation#GO:0033046;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;telophase#GO:0051326;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;M phase#GO:0000279;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of mitotic sister chromatid segregation#GO:0033047;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;negative regulation of cellular component organization#GO:0051129;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;meiosis I cell cycle phase#GO:0098764;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;cellular component organization#GO:0016043;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;regulation of chromosome separation#GO:1905818;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;cell cycle phase#GO:0022403;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;negative regulation of chromosome separation#GO:1905819;meiotic nuclear division#GO:0140013;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;biological phase#GO:0044848;cell cycle#GO:0007049;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=31304|UniProtKB=A6NL08 A6NL08 OR6C75 PTHR26454:SF79 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C75 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=35153|UniProtKB=A6NFU0 A6NFU0 FAM187A PTHR32178:SF7 FAM187 IG-LIKE V-TYPE DOMAIN-CONTAINING PROTEIN FAM187A immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=8189|UniProtKB=P30953 P30953 OR1E1 PTHR48001:SF130 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1E1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=33859|UniProtKB=Q6ZSG2 Q6ZSG2 INSYN2A PTHR28682:SF1 INHIBITORY SYNAPTIC FACTOR 2A-RELATED INHIBITORY SYNAPTIC FACTOR 2A cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;chemical synaptic transmission, postsynaptic#GO:0099565;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;asymmetric synapse#GO:0032279 HUMAN|HGNC=25100|UniProtKB=Q9BVM4 Q9BVM4 GGACT PTHR12510:SF4 TROPONIN C-AKIN-1 PROTEIN GAMMA-GLUTAMYLAMINECYCLOTRANSFERASE HUMAN|HGNC=10597|UniProtKB=Q15858 Q15858 SCN9A PTHR10037:SF221 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 9 SUBUNIT ALPHA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sodium channel activity#GO:0005272;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;sodium ion transport#GO:0006814;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=29173|UniProtKB=Q674X7 Q674X7 KAZN PTHR12776:SF1 KAZRIN-RELATED KAZRIN HUMAN|HGNC=70|UniProtKB=Q8NE71 Q8NE71 ABCF1 PTHR19211:SF14 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 translation elongation factor#PC00222 HUMAN|HGNC=18107|UniProtKB=P0DP74 P0DP74 DEFB130A PTHR20515:SF1 BETA-DEFENSIN BETA-DEFENSIN 130A-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;interspecies interaction between organisms#GO:0044419;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;localization#GO:0051179;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;response to chemical#GO:0042221;defense response to other organism#GO:0098542;response to other organism#GO:0051707;movement of cell or subcellular component#GO:0006928;defense response#GO:0006952;cell migration#GO:0016477;locomotion#GO:0040011;chemotaxis#GO:0006935;taxis#GO:0042330 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=31750|UniProtKB=Q8N8I0 Q8N8I0 SAMD12 PTHR20843:SF2 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 12 HUMAN|HGNC=22516|UniProtKB=P0C5Y9 P0C5Y9 H2AB1 PTHR23430:SF23 HISTONE H2A HISTONE H2A-BBD TYPE 1-RELATED heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=19002|UniProtKB=Q8N568 Q8N568 DCLK2 PTHR24347:SF376 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE DCLK2 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=9411|UniProtKB=P14314 P14314 PRKCSH PTHR12630:SF1 N-LINKED OLIGOSACCHARIDE PROCESSING GLUCOSIDASE 2 SUBUNIT BETA carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095 HUMAN|HGNC=11944|UniProtKB=P02585 P02585 TNNC2 PTHR23064:SF21 TROPONIN TROPONIN C, SKELETAL MUSCLE cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;actin filament binding#GO:0051015;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ion binding#GO:0043167;actin binding#GO:0003779 regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;regulation of muscle contraction#GO:0006937;skeletal muscle contraction#GO:0003009;system process#GO:0003008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of system process#GO:0044057;striated muscle contraction#GO:0006941;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=11447|UniProtKB=Q8WUJ0 Q8WUJ0 STYX PTHR46588:SF1 SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN protein binding#GO:0005515;binding#GO:0005488 negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;intracellular signal transduction#GO:0035556;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;negative regulation of protein catabolic process#GO:0042177;regulation of signaling#GO:0023051;organonitrogen compound catabolic process#GO:1901565;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of proteolysis involved in cellular protein catabolic process#GO:1903051;catabolic process#GO:0009056;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;ERK1 and ERK2 cascade#GO:0070371;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular catabolic process#GO:0031330;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein catabolic process#GO:1903363;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;negative regulation of molecular function#GO:0044092 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=28698|UniProtKB=Q8TF46 Q8TF46 DIS3L PTHR23355:SF30 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity#GO:0003824;ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 protein-containing complex#GO:0032991;exosome (RNase complex)#GO:0000178;intracellular#GO:0005622;catalytic complex#GO:1902494 exoribonuclease#PC00099 HUMAN|HGNC=33748|UniProtKB=Q6BDI9 Q6BDI9 REP15 PTHR36682:SF1 RAB15 EFFECTOR PROTEIN RAB15 EFFECTOR PROTEIN HUMAN|HGNC=1041|UniProtKB=Q13515 Q13515 BFSP2 PTHR23239:SF32 INTERMEDIATE FILAMENT PHAKININ HUMAN|HGNC=26594|UniProtKB=Q18PE1 Q18PE1 DOK7 PTHR21636:SF2 PROTEIN DOK-7 PROTEIN DOK-7 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;neuromuscular junction development#GO:0007528;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;peptidyl-tyrosine modification#GO:0018212;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 HUMAN|Ensembl=ENSG00000234828|UniProtKB=A0A1B0GVH7 A0A1B0GVH7 IQCM PTHR35978:SF1 IQ DOMAIN-CONTAINING PROTEIN M IQ DOMAIN-CONTAINING PROTEIN M HUMAN|HGNC=9002|UniProtKB=P48739 P48739 PITPNB PTHR10658:SF27 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN BETA ISOFORM cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transporter#PC00227 HUMAN|HGNC=30251|UniProtKB=Q13145 Q13145 BAMBI PTHR15505:SF1 RIIA DOMAIN-CONTAINING PROTEIN 1 BMP AND ACTIVIN MEMBRANE-BOUND INHIBITOR HOMOLOG protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;signaling#GO:0023052 TGF-beta signaling pathway#P00052>BAMBI#P01287 HUMAN|HGNC=16038|UniProtKB=Q8N138 Q8N138 ORMDL3 PTHR12665:SF11 ORMDL PROTEINS ORM1-LIKE PROTEIN 3 negative regulation of cellular metabolic process#GO:0031324;lipid metabolic process#GO:0006629;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;biosynthetic process#GO:0009058;cellular homeostasis#GO:0019725;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of cellular component biogenesis#GO:0044087;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of lipid biosynthetic process#GO:0046890;negative regulation of cellular process#GO:0048523;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;chemical homeostasis#GO:0048878;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;cellular chemical homeostasis#GO:0055082;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;membrane lipid metabolic process#GO:0006643;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;ceramide biosynthetic process#GO:0046513;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;regulation of lipid metabolic process#GO:0019216;cellular lipid metabolic process#GO:0044255;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=32416|UniProtKB=A6NKT7 A6NKT7 RGPD3 PTHR23138:SF87 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26213|UniProtKB=Q9H628 Q9H628 RERGL PTHR45704:SF9 RAS-LIKE FAMILY MEMBER 11 RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR-LIKE PROTEIN HUMAN|HGNC=16820|UniProtKB=Q14162 Q14162 SCARF1 PTHR24043:SF0 SCAVENGER RECEPTOR CLASS F SCAVENGER RECEPTOR CLASS F MEMBER 1 membrane traffic protein#PC00150 HUMAN|HGNC=10593|UniProtKB=Q14524 Q14524 SCN5A PTHR10037:SF206 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sodium channel activity#GO:0005272;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 blood circulation#GO:0008015;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;action potential#GO:0001508;regulation of system process#GO:0044057;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;ion homeostasis#GO:0050801;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of multicellular organismal process#GO:0051239;transmembrane transport#GO:0055085;regulation of heart contraction#GO:0008016;ion transport#GO:0006811;regulation of membrane potential#GO:0042391;heart contraction#GO:0060047;trans-synaptic signaling#GO:0099537;homeostatic process#GO:0042592;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;chemical homeostasis#GO:0048878;circulatory system process#GO:0003013;ion transmembrane transport#GO:0034220;localization#GO:0051179;sodium ion transport#GO:0006814;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart process#GO:0003015;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=11273|UniProtKB=Q13813 Q13813 SPTAN1 PTHR11915:SF427 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1 HUMAN|HGNC=14977|UniProtKB=Q9Y5W7 Q9Y5W7 SNX14 PTHR22775:SF44 SORTING NEXIN SORTING NEXIN-14 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9280|UniProtKB=P50336 P50336 PPOX PTHR42923:SF3 PROTOPORPHYRINOGEN OXIDASE PROTOPORPHYRINOGEN OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 Heme biosynthesis#P02746>Protoporphyrinogen oxidase#P02976 HUMAN|HGNC=14859|UniProtKB=Q9HA47 Q9HA47 UCK1 PTHR10285:SF66 URIDINE KINASE URIDINE-CYTIDINE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 HUMAN|HGNC=16254|UniProtKB=Q8TDR2 Q8TDR2 STK35 PTHR11042:SF59 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED SERINE/THREONINE-PROTEIN KINASE 35 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=6703|UniProtKB=Q9Y608 Q9Y608 LRRFIP2 PTHR19212:SF6 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 2 DNA-binding transcription factor#PC00218 HUMAN|HGNC=17470|UniProtKB=Q6UW88 Q6UW88 EPGN PTHR10740:SF10 TRANSFORMING GROWTH FACTOR ALPHA EPIGEN regulation of protein modification process#GO:0031399;regulation of mitotic nuclear division#GO:0007088;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of organelle organization#GO:0033043;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell cycle process#GO:0090068;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of mitotic cell cycle#GO:0007346 growth factor#PC00112 HUMAN|HGNC=13587|UniProtKB=Q9NRD0 Q9NRD0 FBXO8 PTHR10663:SF372 GUANYL-NUCLEOTIDE EXCHANGE FACTOR F-BOX ONLY PROTEIN 8 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=29250|UniProtKB=Q9P2L0 Q9P2L0 WDR35 PTHR16517:SF1 TUBBY-RELATED WD REPEAT-CONTAINING PROTEIN 35 HUMAN|HGNC=26224|UniProtKB=Q9H5Z6 Q9H5Z6 FAM124B PTHR14715:SF2 FAMILY NOT NAMED PROTEIN FAM124B membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18324|UniProtKB=Q9H2F3 Q9H2F3 HSD3B7 PTHR10366:SF387 NAD DEPENDENT EPIMERASE/DEHYDRATASE 3 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 7 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091 Androgen/estrogene/progesterone biosynthesis#P02727>3beta-hydroxy-Delta5-steroid dehydrogenase#P02837 HUMAN|HGNC=21155|UniProtKB=Q8WY64 Q8WY64 MYLIP PTHR23280:SF13 4.1 G PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MYLIP HUMAN|HGNC=2195|UniProtKB=P39060 P39060 COL18A1 PTHR24023:SF1034 COLLAGEN ALPHA COLLAGEN ALPHA-1(XVIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=25551|UniProtKB=Q8ND04 Q8ND04 SMG8 PTHR13091:SF0 AMPLIFIED IN BREAST CANCER 2-RELATED PROTEIN SMG8 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 HUMAN|HGNC=4496|UniProtKB=O43194 O43194 GPR39 PTHR46752:SF1 G-PROTEIN COUPLED RECEPTOR 39 G-PROTEIN COUPLED RECEPTOR 39 G-protein coupled receptor#PC00021 HUMAN|HGNC=2545|UniProtKB=P25774 P25774 CTSS PTHR12411:SF525 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN S cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=20980|UniProtKB=Q6UXK5 Q6UXK5 LRRN1 PTHR24373:SF97 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT NEURONAL PROTEIN 1 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=25380|UniProtKB=Q8TC26 Q8TC26 TMEM163 PTHR31937:SF2 TRANSMEMBRANE PROTEIN 163 TRANSMEMBRANE PROTEIN 163 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=5194|UniProtKB=O14792 O14792 HS3ST1 PTHR10605:SF16 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 HUMAN|HGNC=352|UniProtKB=P55008 P55008 AIF1 PTHR10356:SF4 ALLOGRAFT INFLAMMATORY FACTOR-1 ALLOGRAFT INFLAMMATORY FACTOR 1 cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;actin filament binding#GO:0051015;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ion binding#GO:0043167;actin binding#GO:0003779 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;plasma membrane bounded cell projection assembly#GO:0120031 supramolecular complex#GO:0099080;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;ruffle membrane#GO:0032587;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;ruffle#GO:0001726;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 calmodulin-related#PC00061 HUMAN|HGNC=33714|UniProtKB=A5D6W6 A5D6W6 FITM1 PTHR23129:SF3 UNCHARACTERIZED FAT STORAGE-INDUCING TRANSMEMBRANE PROTEIN 1 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;maintenance of location#GO:0051235;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;lipid localization#GO:0010876;lipid storage#GO:0019915;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=12932|UniProtKB=Q14258 Q14258 TRIM25 PTHR25465:SF17 FAMILY NOT NAMED E3 UBIQUITIN/ISG15 LIGASE TRIM25 HUMAN|HGNC=18320|UniProtKB=Q7RTV3 Q7RTV3 ZNF367 PTHR23235:SF51 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 367 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6698|UniProtKB=O75581 O75581 LRP6 PTHR24270:SF12 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6 apolipoprotein#PC00052 Wnt signaling pathway#P00057>LRP5/6#P01431;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 HUMAN|HGNC=1602|UniProtKB=P32246 P32246 CCR1 PTHR10489:SF711 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 1 protein binding#GO:0005515;C-C chemokine binding#GO:0019957;binding#GO:0005488;chemokine binding#GO:0019956;cytokine binding#GO:0019955 response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response#GO:0006952;immune response#GO:0006955;inflammatory response#GO:0006954 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=26157|UniProtKB=Q9H6R7 Q9H6R7 WDCP PTHR14897:SF5 WD REPEAT AND COILED-COIL-CONTAINING PROTEIN WD REPEAT AND COILED-COIL-CONTAINING PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=29843|UniProtKB=Q6X4W1 Q6X4W1 NSMF PTHR32061:SF4 NMDA RECEPTOR SYNAPTONUCLEAR SIGNALING AND NEURONAL MIGRATION FACTOR NMDA RECEPTOR SYNAPTONUCLEAR SIGNALING AND NEURONAL MIGRATION FACTOR HUMAN|HGNC=25301|UniProtKB=Q5HY64 Q5HY64 FAM47C PTHR47415:SF2 PROTEIN FAM47B PROTEIN FAM47C-RELATED HUMAN|HGNC=18145|UniProtKB=Q8IWS0 Q8IWS0 PHF6 PTHR12420:SF15 PHD FINGER PROTEIN PHD FINGER PROTEIN 6 enzyme binding#GO:0019899;protein binding#GO:0005515;histone deacetylase binding#GO:0042826;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=7035|UniProtKB=P55083 P55083 MFAP4 PTHR19143:SF225 FIBRINOGEN/TENASCIN/ANGIOPOEITIN MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 4 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;extracellular structure organization#GO:0043062;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=13448|UniProtKB=Q96QD8 Q96QD8 SLC38A2 PTHR22950:SF207 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 amino acid transporter#PC00046 HUMAN|HGNC=2747|UniProtKB=P26196 P26196 DDX6 PTHR47960:SF2 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 ATP-DEPENDENT RNA HELICASE DDX6-RELATED nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoplasmic mRNA processing body assembly#GO:0033962;cellular process#GO:0009987 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=13871|UniProtKB=Q16630 Q16630 CPSF6 PTHR23204:SF3 CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6 RNA processing factor#PC00147 HUMAN|HGNC=12513|UniProtKB=P09936 P09936 UCHL1 PTHR10589:SF19 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L1 hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 Parkinson disease#P00049>UCH-L1#P01210 HUMAN|HGNC=9726|UniProtKB=P11217 P11217 PYGM PTHR11468:SF13 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, MUSCLE FORM transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;transferase activity, transferring glycosyl groups#GO:0016757;anion binding#GO:0043168;ion binding#GO:0043167 glucan metabolic process#GO:0044042;macromolecule catabolic process#GO:0009057;glycogen metabolic process#GO:0005977;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;cellular glucan metabolic process#GO:0006073;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 HUMAN|HGNC=30519|UniProtKB=Q969I3 Q969I3 GLYATL1 PTHR15298:SF7 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 1 transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 oxoacid metabolic process#GO:0043436;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid metabolic process#GO:0006520;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=10769|UniProtKB=Q13435 Q13435 SF3B2 PTHR12785:SF6 SPLICING FACTOR 3B SPLICING FACTOR 3B SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974;U12-type spliceosomal complex#GO:0005689 RNA splicing factor#PC00148 HUMAN|HGNC=4463|UniProtKB=P46091 P46091 GPR1 PTHR24229:SF4 NEUROPEPTIDES RECEPTOR G-PROTEIN COUPLED RECEPTOR 1 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=18661|UniProtKB=Q8WXX0 Q8WXX0 DNAH7 PTHR10676:SF310 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN 7, AXONEMAL pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement#GO:0003341 supramolecular complex#GO:0099080;axoneme#GO:0005930;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=3531|UniProtKB=P00488 P00488 F13A1 PTHR11590:SF42 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE COAGULATION FACTOR XIII A CHAIN transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of body fluid levels#GO:0050878;cellular metabolic process#GO:0044237;wound healing#GO:0042060;cellular process#GO:0009987;hemostasis#GO:0007599;coagulation#GO:0050817;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;protein activation cascade#GO:0072376;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transferase#PC00220 Blood coagulation#P00011>FXIII#P00453;Blood coagulation#P00011>FXIIIa#P00419 HUMAN|HGNC=15783|UniProtKB=Q6P4F7 Q6P4F7 ARHGAP11A PTHR15670:SF4 RHO GTPASE ACTIVATING PROTEIN 11A RHO GTPASE-ACTIVATING PROTEIN 11A-RELATED GTPase-activating protein#PC00257 HUMAN|HGNC=14098|UniProtKB=Q9GZL7 Q9GZL7 WDR12 PTHR19855:SF11 WD40 REPEAT PROTEIN 12, 37 RIBOSOME BIOGENESIS PROTEIN WDR12 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991 HUMAN|HGNC=30719|UniProtKB=Q9UJT2 Q9UJT2 TSKS PTHR14351:SF1 TESTIS-SPECIFIC SERINE KINASE SUBSTRATE TESTIS-SPECIFIC SERINE KINASE SUBSTRATE enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4084|UniProtKB=O14764 O14764 GABRD PTHR18945:SF34 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT DELTA signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;system process#GO:0003008;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=30167|UniProtKB=P13667 P13667 PDIA4 PTHR18929:SF210 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A4 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;cellular process#GO:0009987;cellular response to stress#GO:0033554;protein folding#GO:0006457 cytoplasm#GO:0005737;cell surface#GO:0009986;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=25214|UniProtKB=Q6ZR62 Q6ZR62 RTL4 PTHR15503:SF8 LDOC1 RELATED RETROTRANSPOSON GAG-LIKE PROTEIN 4 HUMAN|HGNC=16245|UniProtKB=Q9BYG5 Q9BYG5 PARD6B PTHR14102:SF4 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG BETA Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;kinase binding#GO:0019900 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of localization#GO:0032879;cellular component organization#GO:0016043;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;regulation of biological process#GO:0050789;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 tight junction#PC00214 HUMAN|HGNC=10723|UniProtKB=Q14563 Q14563 SEMA3A PTHR11036:SF23 SEMAPHORIN SEMAPHORIN-3A receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;negative regulation of cellular component organization#GO:0051129;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;negative regulation of locomotion#GO:0040013;neuron projection extension#GO:1990138;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;positive regulation of multicellular organismal process#GO:0051240;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;signal transduction#GO:0007165;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;growth#GO:0040007;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;developmental growth involved in morphogenesis#GO:0060560;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of cell differentiation#GO:0045597;regulation of cell motility#GO:2000145;regulation of cell development#GO:0060284;developmental growth#GO:0048589;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell motility#GO:0048870;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;positive regulation of developmental process#GO:0051094;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;motor neuron axon guidance#GO:0008045;regulation of developmental process#GO:0050793;neuron migration#GO:0001764;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 Axon guidance mediated by semaphorins#P00007>Sema3A#P00337 HUMAN|HGNC=33734|UniProtKB=A0A0A6YYL3 A0A0A6YYL3 POTEB PTHR24118:SF65 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER B-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=2711|UniProtKB=Q14203 Q14203 DCTN1 PTHR18916:SF6 DYNACTIN 1-RELATED MICROTUBULE-BINDING DYNACTIN SUBUNIT 1 chaperone#PC00072 Huntington disease#P00029>Dynactin#P00781 HUMAN|HGNC=41983|UniProtKB=P0DM63 P0DM63 NPIPA8 PTHR15438:SF14 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER A1-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=53611|UniProtKB=P0DPD7 P0DPD7 EEF1AKMT4 PTHR12176:SF71 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN CITRATE SYNTHASE-LYSINE N-METHYLTRANSFERASE CSKMT, MITOCHONDRIAL-RELATED methyltransferase#PC00155 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=20773|UniProtKB=Q3ZCM7 Q3ZCM7 TUBB8 PTHR11588:SF55 TUBULIN TUBULIN BETA 8B-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 HUMAN|HGNC=888|UniProtKB=Q12756 Q12756 KIF1A PTHR24115:SF361 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;ATP-dependent microtubule motor activity, plus-end-directed#GO:0008574;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 supramolecular complex#GO:0099080;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;dendritic tree#GO:0097447;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 HUMAN|Ensembl=ENSG00000279493|UniProtKB=A0A096LPK6 A0A096LPK6 ENSG00000279493 PTHR23068:SF13 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3-LIKE DNA methyltransferase#PC00013 HUMAN|HGNC=11947|UniProtKB=P19429 P19429 TNNI3 PTHR13738:SF2 TROPONIN I TROPONIN I, CARDIAC MUSCLE multicellular organismal process#GO:0032501;muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008 supramolecular complex#GO:0099080;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 non-motor actin binding protein#PC00165 HUMAN|HGNC=8136|UniProtKB=P47874 P47874 OMP PTHR15357:SF0 OLFACTORY MARKER PROTEIN OLFACTORY MARKER PROTEIN HUMAN|HGNC=25082|UniProtKB=Q8WU79 Q8WU79 SMAP2 PTHR45705:SF4 FI20236P1 STROMAL MEMBRANE-ASSOCIATED PROTEIN 2 GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 HUMAN|HGNC=13397|UniProtKB=Q9UHQ9 Q9UHQ9 CYB5R1 PTHR19370:SF74 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE 1 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 reductase#PC00198 HUMAN|HGNC=25612|UniProtKB=Q8IZM8 Q8IZM8 ZNF654 PTHR15507:SF16 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN 654 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26659|UniProtKB=Q8NA70 Q8NA70 FAM47B PTHR47415:SF1 PROTEIN FAM47B PROTEIN FAM47B HUMAN|HGNC=5457|UniProtKB=Q12894 Q12894 IFRD2 PTHR12354:SF8 INTERFERON-RELATED DEVELOPMENTAL REGULATOR INTERFERON-RELATED DEVELOPMENTAL REGULATOR 2 HUMAN|HGNC=1638|UniProtKB=P15812 P15812 CD1E PTHR16675:SF146 MHC CLASS I-RELATED T-CELL SURFACE GLYCOPROTEIN CD1E, MEMBRANE-ASSOCIATED lipid binding#GO:0008289;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 immune response#GO:0006955;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;T cell mediated immunity#GO:0002456;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=26333|UniProtKB=Q8NEF9 Q8NEF9 SRFBP1 PTHR23325:SF1 SERUM RESPONSE FACTOR-BINDING SERUM RESPONSE FACTOR-BINDING PROTEIN 1 RNA metabolism protein#PC00031 HUMAN|HGNC=23644|UniProtKB=A2A2Z9 A2A2Z9 ANKRD18B PTHR24147:SF59 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 18B HUMAN|HGNC=32958|UniProtKB=A6NEL2 A6NEL2 SOWAHB PTHR14491:SF3 UNCHARACTERIZED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHB HUMAN|HGNC=25331|UniProtKB=Q8NDQ6 Q8NDQ6 ZNF540 PTHR24377:SF138 IP01015P-RELATED ZINC FINGER PROTEIN 540 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8526|UniProtKB=Q15070 Q15070 OXA1L PTHR12428:SF34 OXA1 MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L small molecule binding#GO:0036094;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;mitochondrial respiratory chain complex assembly#GO:0033108;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;cytochrome complex assembly#GO:0017004;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;mitochondrial cytochrome c oxidase assembly#GO:0033617;protein insertion into membrane#GO:0051205;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein localization to membrane#GO:0072657;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 transporter#PC00227 HUMAN|HGNC=33757|UniProtKB=Q6QAJ8 Q6QAJ8 TMEM220 PTHR34262:SF1 TRANSMEMBRANE PROTEIN 220 TRANSMEMBRANE PROTEIN 220 HUMAN|HGNC=7067|UniProtKB=P33076 P33076 CIITA PTHR47189:SF1 MHC CLASS II TRANSACTIVATOR MHC CLASS II TRANSACTIVATOR protein binding#GO:0005515;activating transcription factor binding#GO:0033613;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;inflammatory response#GO:0006954;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 HUMAN|HGNC=601|UniProtKB=P02652 P02652 APOA2 PTHR11027:SF0 APOLIPOPROTEIN A-II APOLIPOPROTEIN A-II apolipoprotein#PC00052 HUMAN|HGNC=2684|UniProtKB=Q15038 Q15038 DAZAP2 PTHR31638:SF4 DAZ-ASSOCIATED PROTEIN 2 DAZ-ASSOCIATED PROTEIN 2 HUMAN|HGNC=28805|UniProtKB=Q9H4I3 Q9H4I3 TRABD PTHR21530:SF7 PHEROMONE SHUTDOWN PROTEIN TRAB DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=23750|UniProtKB=Q6NW29 Q6NW29 RWDD4 PTHR21275:SF1 UNCHARACTERIZED RWD DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=10632|UniProtKB=P13501 P13501 CCL5 PTHR12015:SF170 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 5 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=2309|UniProtKB=O14810 O14810 CPLX1 PTHR16705:SF6 COMPLEXIN COMPLEXIN-1 syntaxin binding#GO:0019905;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488;syntaxin-1 binding#GO:0017075 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;cell junction#GO:0030054;SNARE complex#GO:0031201;terminal bouton#GO:0043195;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=2384|UniProtKB=Q16526 Q16526 CRY1 PTHR11455:SF16 CRYPTOCHROME CRYPTOCHROME-1 nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;response to radiation#GO:0009314;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;response to light stimulus#GO:0009416;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA photolyase#PC00014 Circadian clock system#P00015>Cry#P00505;Circadian clock system#P00015>cry#G01497;Circadian clock system#P00015>cry#G01501 HUMAN|HGNC=21529|UniProtKB=Q9HD45 Q9HD45 TM9SF3 PTHR10766:SF41 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=7214|UniProtKB=Q99547 Q99547 MPHOSPH6 PTHR13582:SF0 M-PHASE PHOSPHOPROTEIN 6 M-PHASE PHOSPHOPROTEIN 6 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=8801|UniProtKB=Q9NRA1 Q9NRA1 PDGFC PTHR11633:SF5 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR C growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component movement#GO:0051272;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;inositol lipid-mediated signaling#GO:0048017;positive regulation of ERK1 and ERK2 cascade#GO:0070374;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;regulation of protein serine/threonine kinase activity#GO:0071900;protein autophosphorylation#GO:0046777;phosphatidylinositol-mediated signaling#GO:0048015;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;ERK1 and ERK2 cascade#GO:0070371;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of cell migration#GO:0030335;phosphatidylinositol 3-kinase signaling#GO:0014065;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of phosphatidylinositol 3-kinase signaling#GO:0014066;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477;regulation of transferase activity#GO:0051338 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224 HUMAN|HGNC=25907|UniProtKB=Q96ST8 Q96ST8 CEP89 PTHR36170:SF1 CENTROSOMAL PROTEIN OF 89 KDA CENTROSOMAL PROTEIN OF 89 KDA HUMAN|HGNC=26169|UniProtKB=Q2NKJ3 Q2NKJ3 CTC1 PTHR14865:SF2 CST COMPLEX SUBUNIT CTC1 CST COMPLEX SUBUNIT CTC1 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;telomere maintenance via telomere lengthening#GO:0010833;positive regulation of DNA replication#GO:0045740;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;nuclear telomere cap complex#GO:0000783;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781;protein-DNA complex#GO:0032993;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7749|UniProtKB=Q9HC98 Q9HC98 NEK6 PTHR43289:SF13 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED SERINE/THREONINE-PROTEIN KINASE NEK6 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=34349|UniProtKB=A6NCI8 A6NCI8 C2orf78 PTHR31466:SF1 GENE 5591-RELATED DUF4629 DOMAIN-CONTAINING PROTEIN-RELATED HUMAN|HGNC=11152|UniProtKB=P09661 P09661 SNRPA1 PTHR10552:SF6 U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A' RNA splicing factor#PC00148 HUMAN|HGNC=3563|UniProtKB=Q0Z7S8 Q0Z7S8 FABP9 PTHR11955:SF70 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN 9 HUMAN|HGNC=26068|UniProtKB=Q6IAA8 Q6IAA8 LAMTOR1 PTHR13401:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR1 RAGULATOR COMPLEX PROTEIN LAMTOR1 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;molecular function regulator#GO:0098772;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 cellular localization#GO:0051641;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;protein modification process#GO:0036211;MAPK cascade#GO:0000165;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;vesicle organization#GO:0016050;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;vesicle budding from membrane#GO:0006900;response to chemical#GO:0042221;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;lytic vacuole#GO:0000323;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane raft#GO:0045121;late endosome#GO:0005770;membrane region#GO:0098589;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 HUMAN|HGNC=13273|UniProtKB=Q9NRD8 Q9NRD8 DUOX2 PTHR11972:SF67 NADPH OXIDASE DUAL OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;oxidoreductase complex#GO:1990204;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175 HUMAN|HGNC=19411|UniProtKB=Q86VH4 Q86VH4 LRRTM4 PTHR24373:SF283 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 4 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=3308|UniProtKB=Q9UNI1 Q9UNI1 CELA1 PTHR24257:SF0 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 1 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=7723|UniProtKB=Q8NHV4 Q8NHV4 NEDD1 PTHR44414:SF1 PROTEIN NEDD1 PROTEIN NEDD1 localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 spindle pole#GO:0000922;microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=13178|UniProtKB=Q9UKT9 Q9UKT9 IKZF3 PTHR24404:SF23 ZINC FINGER PROTEIN ZINC FINGER PROTEIN AIOLOS cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=24288|UniProtKB=Q8NE62 Q8NE62 CHDH PTHR11552:SF147 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE CHOLINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 HUMAN|HGNC=14516|UniProtKB=Q9Y676 Q9Y676 MRPS18B PTHR13329:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S18B 28S RIBOSOMAL PROTEIN S18B, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ribosomal protein#PC00202 HUMAN|HGNC=21839|UniProtKB=A9QM74 A9QM74 KPNA7 PTHR23316:SF11 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-8 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=8633|UniProtKB=P40425 P40425 PBX2 PTHR11850:SF50 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;sensory system development#GO:0048880;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;neuron development#GO:0048666;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;visual system development#GO:0150063;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=7786|UniProtKB=P08651 P08651 NFIC PTHR11492:SF2 NUCLEAR FACTOR I NUCLEAR FACTOR 1 C-TYPE cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=26062|UniProtKB=Q96HA4 Q96HA4 C1orf159 PTHR16247:SF0 RIKEN CDNA 9430015G10 GENE RIKEN CDNA 9430015G10 GENE HUMAN|HGNC=1633|UniProtKB=P15391 P15391 CD19 PTHR16674:SF2 B-LYMPHOCYTE ANTIGEN CD19 B-LYMPHOCYTE ANTIGEN CD19 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;B cell receptor signaling pathway#GO:0050853;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of biological process#GO:0048518;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 B cell activation#P00010>CD19#P00393 HUMAN|HGNC=3083|UniProtKB=Q96PT3 Q96PT3 DUX5 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=9973|UniProtKB=P40937 P40937 RFC5 PTHR11669:SF9 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 5 pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 HUMAN|HGNC=8368|UniProtKB=Q15622 Q15622 OR7A5 PTHR48001:SF177 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7A5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|Gene=NPEPPSL1|UniProtKB=A6NEC2 A6NEC2 NPEPPSL1 PTHR11533:SF285 PROTEASE M1 ZINC METALLOPROTEASE PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED cation binding#GO:0043169;metallopeptidase activity#GO:0008237;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;peptide binding#GO:0042277;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;peptidase activity#GO:0008233;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=29872|UniProtKB=Q8NET5 Q8NET5 NFAM1 PTHR35680:SF1 NFAT ACTIVATION MOLECULE 1 NFAT ACTIVATION MOLECULE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;B cell receptor signaling pathway#GO:0050853;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of biological process#GO:0048518;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;membrane raft#GO:0045121;membrane#GO:0016020;integral component of membrane#GO:0016021;membrane microdomain#GO:0098857;membrane region#GO:0098589;whole membrane#GO:0098805 HUMAN|HGNC=26177|UniProtKB=Q6UXD7 Q6UXD7 SLC49A3 PTHR10924:SF6 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER A3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=27263|UniProtKB=Q5T7N3 Q5T7N3 KANK4 PTHR24168:SF24 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 4 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=24928|UniProtKB=Q8NEZ2 Q8NEZ2 VPS37A PTHR13678:SF20 WILLIAMS-BEUREN SYNDROME CRITICAL REGION PROTEIN-RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A protein catabolic process in the vacuole#GO:0007039;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;multivesicular body sorting pathway#GO:0071985;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;cellular protein catabolic process#GO:0044257;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=11396|UniProtKB=O94768 O94768 STK17B PTHR24342:SF5 SERINE/THREONINE-PROTEIN KINASE 17 SERINE/THREONINE-PROTEIN KINASE 17B transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;intracellular signal transduction#GO:0035556;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=28294|UniProtKB=Q8IYU4 Q8IYU4 UBQLNL PTHR10677:SF9 UBIQUILIN UBIQUILIN-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=25553|UniProtKB=Q9NVN8 Q9NVN8 GNL3L PTHR11089:SF33 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3-LIKE PROTEIN intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5109|UniProtKB=P31269 P31269 HOXA9 PTHR45970:SF3 AGAP004664-PA HOMEOBOX PROTEIN HOX-A9 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=33511|UniProtKB=A6NLF2 A6NLF2 ELOA3D PTHR15141:SF74 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN-A3-RELATED HUMAN|HGNC=21172|UniProtKB=Q7Z6V5 Q7Z6V5 ADAT2 PTHR11079:SF149 CYTOSINE DEAMINASE FAMILY MEMBER TRNA-SPECIFIC ADENOSINE DEAMINASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 deaminase#PC00088 Salvage pyrimidine ribonucleotides#P02775>Cytosine deaminase#P03155;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCTP deaminase#P02920 HUMAN|HGNC=6483|UniProtKB=Q16787 Q16787 LAMA3 PTHR10574:SF285 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-3 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=91|UniProtKB=P45954 P45954 ACADSB PTHR43884:SF1 ACYL-COA DEHYDROGENASE SHORT/BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092 HUMAN|HGNC=8955|UniProtKB=P50453 P50453 SERPINB9 PTHR11461:SF350 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B9 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 protease inhibitor#PC00191 HUMAN|HGNC=11864|UniProtKB=O15321 O15321 TM9SF1 PTHR10766:SF14 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 1 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=18487|UniProtKB=Q8IZP2 Q8IZP2 ST13P4 PTHR45883:SF3 HSC70-INTERACTING PROTEIN PROTEIN FAM10A4-RELATED protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chaperone-mediated protein folding#GO:0061077;protein folding#GO:0006457;protein-containing complex assembly#GO:0065003;'de novo' protein folding#GO:0006458;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 HUMAN|HGNC=17213|UniProtKB=Q9BWP8 Q9BWP8 COLEC11 PTHR24024:SF14 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A COLLECTIN-11 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212 HUMAN|HGNC=30477|UniProtKB=Q6MZM0 Q6MZM0 HEPHL1 PTHR11709:SF233 MULTI-COPPER OXIDASE FERROXIDASE HEPHL1 ferroxidase activity#GO:0004322;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;cation transport#GO:0006812;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;localization#GO:0051179;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;establishment of localization#GO:0051234;iron ion homeostasis#GO:0055072;biological regulation#GO:0065007;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;metal ion homeostasis#GO:0055065 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175 HUMAN|HGNC=44652|UniProtKB=H3BQW9 H3BQW9 FAM229A PTHR35355:SF1 PROTEIN FAM229A PROTEIN FAM229A HUMAN|HGNC=24787|UniProtKB=Q6ZSS3 Q6ZSS3 ZNF621 PTHR23226:SF155 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 621 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1918|UniProtKB=Q12873 Q12873 CHD3 PTHR45623:SF9 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3 HUMAN|HGNC=15828|UniProtKB=Q9Y272 Q9Y272 RASD1 PTHR46149:SF4 MIP08469P DEXAMETHASONE-INDUCED RAS-RELATED PROTEIN 1 HUMAN|HGNC=24004|UniProtKB=Q70Z44 Q70Z44 HTR3D PTHR18945:SF823 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3D signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=1394|UniProtKB=O43497 O43497 CACNA1G PTHR10037:SF137 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1G calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;system process#GO:0003008;transport#GO:0006810;regulation of secretion by cell#GO:1903530;action potential#GO:0001508;regulation of localization#GO:0032879;cation transport#GO:0006812;calcium ion transport#GO:0006816;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;positive regulation of exocytosis#GO:0045921;regulation of secretion#GO:0051046;secretion#GO:0046903;synaptic signaling#GO:0099536;divalent inorganic cation transport#GO:0072511;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;metal ion transport#GO:0030001;ion transport#GO:0006811;regulation of membrane potential#GO:0042391;positive regulation of secretion#GO:0051047;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cell communication#GO:0007154;nervous system process#GO:0050877;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;positive regulation of cellular process#GO:0048522;localization#GO:0051179;calcium ion import#GO:0070509;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of secretion by cell#GO:1903532;export from cell#GO:0140352 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 Nicotine pharmacodynamics pathway#P06587>CACNA#P06600;Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;GABA-B receptor II signaling#P05731>Ca channel#P05753 HUMAN|HGNC=19871|UniProtKB=Q7Z5H5 Q7Z5H5 VN1R4 PTHR24062:SF176 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 4 transmembrane signal receptor#PC00197 HUMAN|HGNC=29540|UniProtKB=Q9ULX3 Q9ULX3 NOB1 PTHR12814:SF2 RNA-BINDING PROTEIN NOB1 RNA-BINDING PROTEIN NOB1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 preribosome, small subunit precursor#GO:0030688;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991 HUMAN|HGNC=18444|UniProtKB=Q7Z3Z4 Q7Z3Z4 PIWIL4 PTHR22891:SF43 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 4 translation initiation factor#PC00224 HUMAN|HGNC=26746|UniProtKB=Q7Z6I8 Q7Z6I8 C5orf24 PTHR31894:SF0 UPF0461 PROTEIN C5ORF24 UPF0461 PROTEIN C5ORF24 HUMAN|HGNC=10613|UniProtKB=Q16663 Q16663 CCL15 PTHR12015:SF77 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 15 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=17513|UniProtKB=Q9NSB8 Q9NSB8 HOMER2 PTHR10918:SF2 HOMER HOMER PROTEIN HOMOLOG 2 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;metal ion transport#GO:0030001;regulation of metal ion transport#GO:0010959;ion transport#GO:0006811;transport#GO:0006810;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;cell communication#GO:0007154;cation transport#GO:0006812;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;calcium ion transport#GO:0006816;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;divalent inorganic cation transport#GO:0072511;G protein-coupled receptor signaling pathway#GO:0007186;regulation of ion transport#GO:0043269;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;postsynaptic density#GO:0014069;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;asymmetric synapse#GO:0032279;cytoplasm#GO:0005737;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=11533|UniProtKB=Q53T94 Q53T94 TAF1B PTHR31576:SF2 TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 General transcription by RNA polymerase I#P00022>TAF-IB#P00650 HUMAN|HGNC=15461|UniProtKB=P55145 P55145 MANF PTHR12990:SF10 ARMET-LIKE PROTEIN MESENCEPHALIC ASTROCYTE-DERIVED NEUROTROPHIC FACTOR cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=7693|UniProtKB=Q16795 Q16795 NDUFA9 PTHR12126:SF10 NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ubiquinone biosynthetic process#GO:0006744;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176 HUMAN|HGNC=17019|UniProtKB=Q96MT3 Q96MT3 PRICKLE1 PTHR24211:SF15 LIM DOMAIN-CONTAINING PROTEIN PRICKLE-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9382|UniProtKB=P22612 P22612 PRKACG PTHR24353:SF137 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT GAMMA protein kinase A binding#GO:0051018;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein kinase A regulatory subunit binding#GO:0034237;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;anion binding#GO:0043168;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;CCKR signaling map#P06959>PKA-Calpha/beta/gamma#P07099;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Enkephalin release#P05913>PKA#P05972;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-c#P00707;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Endothelin signaling pathway#P00019>PKA#P00570 HUMAN|HGNC=23363|UniProtKB=Q96MC6 Q96MC6 MFSD14A PTHR23504:SF77 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 HIPPOCAMPUS ABUNDANT TRANSCRIPT 1 PROTEIN HUMAN|HGNC=6728|UniProtKB=O94772 O94772 LY6H PTHR32217:SF5 LYMPHOCYTE ANTIGEN 6H LYMPHOCYTE ANTIGEN 6H signaling receptor activity#GO:0038023;receptor regulator activity#GO:0030545;binding#GO:0005488;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;cation binding#GO:0043169;postsynaptic neurotransmitter receptor activity#GO:0098960;acetylcholine receptor activity#GO:0015464;molecular function regulator#GO:0098772;protein binding#GO:0005515;molecular transducer activity#GO:0060089;acetylcholine receptor regulator activity#GO:0030548;ion binding#GO:0043167;acetylcholine binding#GO:0042166 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=6257|UniProtKB=Q14654 Q14654 KCNJ11 PTHR11767:SF44 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 11 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=29162|UniProtKB=Q96BN6 Q96BN6 FAM149B1 PTHR31997:SF0 AGAP003710-PA PROTEIN FAM149B1 HUMAN|HGNC=8882|UniProtKB=P35080 P35080 PFN2 PTHR13936:SF15 PROFILIN PROFILIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 HUMAN|HGNC=8204|UniProtKB=P47890 P47890 OR1G1 PTHR48001:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1G1 transmembrane signal receptor#PC00197 HUMAN|HGNC=18915|UniProtKB=A8MTY7 A8MTY7 KRTAP9-7 PTHR23262:SF133 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-6-RELATED HUMAN|HGNC=5018|UniProtKB=A2RU54 A2RU54 HMX2 PTHR46110:SF4 HOMEOBOX PROTEIN HMX HOMEOBOX PROTEIN HMX2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=3072|UniProtKB=Q16828 Q16828 DUSP6 PTHR10159:SF45 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 6 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;phosphoprotein phosphatase activity#GO:0004721;kinase activity#GO:0016301;kinase binding#GO:0019900;phosphoric ester hydrolase activity#GO:0042578;protein kinase activity#GO:0004672;transferase activity#GO:0016740;MAP kinase activity#GO:0004707;hydrolase activity#GO:0016787;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;regulation of MAP kinase activity#GO:0043405;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;heart development#GO:0007507;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;animal organ development#GO:0048513;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein modification process#GO:0036211;MAPK cascade#GO:0000165;growth#GO:0040007;regulation of growth#GO:0040008;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;positive regulation of programmed cell death#GO:0043068;regulation of protein serine/threonine kinase activity#GO:0071900;cell death#GO:0008219;phosphorylation#GO:0016310;negative regulation of protein kinase activity#GO:0006469;negative regulation of transferase activity#GO:0051348;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;negative regulation of MAP kinase activity#GO:0043407;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;developmental growth#GO:0048589;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of developmental process#GO:0050793;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of cell death#GO:0010941;negative regulation of phosphate metabolic process#GO:0045936;positive regulation of cell death#GO:0010942;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=37234|UniProtKB=Q9H6L2 Q9H6L2 TMEM231 PTHR14605:SF1 CHST5 PROTEIN TRANSMEMBRANE PROTEIN 231 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;regulation of protein localization#GO:0032880;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;vesicle targeting#GO:0006903;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 bounding membrane of organelle#GO:0098588;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;ciliary transition zone#GO:0035869;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=18222|UniProtKB=Q9NWB1 Q9NWB1 RBFOX1 PTHR15597:SF26 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;RNA processing#GO:0006396;gene expression#GO:0010467;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;multicellular organismal process#GO:0032501;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=13615|UniProtKB=Q9UF56 Q9UF56 FBXL17 PTHR16134:SF18 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX/LRR-REPEAT PROTEIN 17 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=8830|UniProtKB=Q9UBM1 Q9UBM1 PEMT PTHR15458:SF5 PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE methyltransferase#PC00155 HUMAN|HGNC=19744|UniProtKB=O43295 O43295 SRGAP3 PTHR14166:SF8 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 3 Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048 regulation of cellular component movement#GO:0051270;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;localization of cell#GO:0051674;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of cell motility#GO:2000146;cell migration#GO:0016477;locomotion#GO:0040011;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=2741|UniProtKB=Q9NVP1 Q9NVP1 DDX18 PTHR24031:SF634 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX18 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=13347|UniProtKB=Q9BS40 Q9BS40 LXN PTHR28591:SF1 LATEXIN LATEXIN metalloendopeptidase activity#GO:0004222;peptidase inhibitor activity#GO:0030414;metallopeptidase activity#GO:0008237;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=26226|UniProtKB=Q5TGS1 Q5TGS1 HES3 PTHR10985:SF5 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=33800|UniProtKB=Q6ZQX7 Q6ZQX7 LIAT1 PTHR36474:SF1 PROTEIN LIAT1 PROTEIN LIAT1 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=26361|UniProtKB=Q14CZ8 Q14CZ8 HEPACAM PTHR12080:SF59 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE HEPATOCYTE CELL ADHESION MOLECULE immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=4603|UniProtKB=P19875 P19875 CXCL2 PTHR10179:SF80 CXC CHEMOKINE C-X-C MOTIF CHEMOKINE 2 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 CCKR signaling map#P06959>CXCL2#G06972;CCKR signaling map#P06959>CXCL2#G07265 HUMAN|HGNC=28031|UniProtKB=Q6PGQ1 Q6PGQ1 DRICH1 PTHR15880:SF0 ASPARTATE-RICH PROTEIN 1 ASPARTATE-RICH PROTEIN 1 HUMAN|HGNC=23459|UniProtKB=Q96P64 Q96P64 AGAP4 PTHR45819:SF7 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 4-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=9357|UniProtKB=P51888 P51888 PRELP PTHR45712:SF8 AGAP008170-PA PROLARGIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=17053|UniProtKB=Q9Y2H5 Q9Y2H5 PLEKHA6 PTHR12752:SF5 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 6 HUMAN|HGNC=30359|UniProtKB=Q9Y534 Q9Y534 CSDC2 PTHR12962:SF4 CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED COLD SHOCK DOMAIN-CONTAINING PROTEIN C2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;regulation of RNA stability#GO:0043487;cellular nitrogen compound metabolic process#GO:0034641;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=12398|UniProtKB=Q9UNY4 Q9UNY4 TTF2 PTHR45626:SF22 TRANSCRIPTION TERMINATION FACTOR 2-RELATED TRANSCRIPTION TERMINATION FACTOR 2 Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 HUMAN|HGNC=19080|UniProtKB=Q9NR34 Q9NR34 MAN1C1 PTHR11742:SF28 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IC hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=18267|UniProtKB=Q96PY5 Q96PY5 FMNL2 PTHR45857:SF5 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;localization of cell#GO:0051674;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;anatomical structure development#GO:0048856;regulation of cell morphogenesis#GO:0022604;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=28033|UniProtKB=Q6PII3 Q6PII3 CCDC174 PTHR15885:SF1 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 174 HUMAN|HGNC=13519|UniProtKB=Q9H1K6 Q9H1K6 TLNRD1 PTHR47133:SF1 TALIN ROD DOMAIN-CONTAINING PROTEIN 1 TALIN ROD DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488;actin binding#GO:0003779 HUMAN|HGNC=12767|UniProtKB=Q9BZ95 Q9BZ95 NSD3 PTHR22884:SF473 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=22954|UniProtKB=Q8NBL1 Q8NBL1 POGLUT1 PTHR12203:SF114 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;UDP-xylosyltransferase activity#GO:0035252;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;glucosyltransferase activity#GO:0046527;xylosyltransferase activity#GO:0042285 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=6341|UniProtKB=Q15726 Q15726 KISS1 PTHR16955:SF6 METASTASIS-SUPPRESSOR KISS-1 METASTASIS-SUPPRESSOR KISS-1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;positive regulation of cytosolic calcium ion concentration#GO:0007204;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;regulation of biological process#GO:0050789;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065;signaling#GO:0023052 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=28295|UniProtKB=Q9BV29 Q9BV29 CCDC32 PTHR31800:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 HUMAN|HGNC=24150|UniProtKB=Q8NG06 Q8NG06 TRIM58 PTHR24103:SF393 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM58 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=25008|UniProtKB=Q9NWV8 Q9NWV8 BABAM1 PTHR15660:SF1 UNCHARACTERIZED BRISC AND BRCA1-A COMPLEX MEMBER 1 HUMAN|HGNC=29160|UniProtKB=Q9NYY8 Q9NYY8 FASTKD2 PTHR21228:SF1 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL HUMAN|HGNC=25473|UniProtKB=Q9P2N6 Q9P2N6 KANSL3 PTHR13136:SF14 TESTIS DEVELOPMENT PROTEIN PRTD KAT8 REGULATORY NSL COMPLEX SUBUNIT 3 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;H4 histone acetyltransferase activity#GO:0010485;N-acyltransferase activity#GO:0016410 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone H4 acetylation#GO:0043967;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;histone H4-K16 acetylation#GO:0043984;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=7463|UniProtKB=P48039 P48039 MTNR1A PTHR24228:SF53 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN RECEPTOR TYPE 1A regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 HUMAN|HGNC=23782|UniProtKB=Q9BY77 Q9BY77 POLDIP3 PTHR19965:SF35 RNA AND EXPORT FACTOR BINDING PROTEIN POLYMERASE DELTA-INTERACTING PROTEIN 3 RNA metabolism protein#PC00031 HUMAN|HGNC=920|UniProtKB=Q9Y2C3 Q9Y2C3 B3GALT5 PTHR11214:SF265 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 5 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=18829|UniProtKB=Q6JEL2 Q6JEL2 KLHL10 PTHR24412:SF172 KELCH PROTEIN KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3712|UniProtKB=P68106 P68106 FKBP1B PTHR10516:SF429 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1B chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 HUMAN|HGNC=20649|UniProtKB=Q8TAQ5 Q8TAQ5 ZNF420 PTHR24377:SF905 IP01015P-RELATED ZINC FINGER PROTEIN 420 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=168|UniProtKB=P42025 P42025 ACTR1B PTHR11937:SF195 ACTIN BETA-CENTRACTIN actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 HUMAN|HGNC=79|UniProtKB=P16442 P16442 ABO PTHR10462:SF29 GLYCOSYLTRANSFERASE-RELATED HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=9392|UniProtKB=P31323 P31323 PRKAR2B PTHR11635:SF156 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE II-BETA REGULATORY SUBUNIT carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;molecular function regulator#GO:0098772;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 protein-containing complex#GO:0032991;intracellular#GO:0005622 kinase modulator#PC00140 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Hedgehog signaling pathway#P00025>PKA#P00682;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Endothelin signaling pathway#P00019>PKA#P00570 HUMAN|HGNC=4568|UniProtKB=Q13905 Q13905 RAPGEF1 PTHR23113:SF224 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 guanyl-nucleotide exchange factor#PC00113 Integrin signalling pathway#P00034>C3G#P00929;PDGF signaling pathway#P00047>SOS#P01159;EGF receptor signaling pathway#P00018>SOS#P00558 HUMAN|HGNC=17968|UniProtKB=Q9UNA3 Q9UNA3 A4GNT PTHR12042:SF16 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;sphingolipid biosynthetic process#GO:0030148;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=9662|UniProtKB=P78324 P78324 SIRPA PTHR19971:SF3 SIGNAL-REGULATORY PROTEIN BETA SIGNAL-REGULATORY PROTEIN BETA-1-RELATED regulation of cell-cell adhesion#GO:0022407;transport#GO:0006810;biological adhesion#GO:0022610;regulation of localization#GO:0032879;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;regulation of vesicle-mediated transport#GO:0060627;leukocyte cell-cell adhesion#GO:0007159;positive regulation of leukocyte activation#GO:0002696;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;lymphocyte activation#GO:0046649;phagocytosis#GO:0006909;positive regulation of immune system process#GO:0002684;vesicle-mediated transport#GO:0016192;cell-cell adhesion#GO:0098609;positive regulation of transport#GO:0051050;cell adhesion#GO:0007155;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of T cell activation#GO:0050870;positive regulation of cell adhesion#GO:0045785;positive regulation of cell activation#GO:0050867;positive regulation of cell-cell adhesion#GO:0022409 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=6944|UniProtKB=P49736 P49736 MCM2 PTHR11630:SF44 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM2 DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;DNA-dependent ATPase activity#GO:0008094;sequence-specific double-stranded DNA binding#GO:1990837;pyrophosphatase activity#GO:0016462;sequence-specific DNA binding#GO:0043565;3'-5' DNA helicase activity#GO:0043138;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;nuclear DNA replication#GO:0033260;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;mitotic DNA replication#GO:1902969;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication initiation#GO:0006270;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;DNA duplex unwinding#GO:0032508;mitotic nuclear division#GO:0140014;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;DNA unwinding involved in DNA replication#GO:0006268;pre-replicative complex assembly involved in nuclear cell cycle DNA replication#GO:0006267;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;cell cycle#GO:0007049;organelle fission#GO:0048285;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;MCM core complex#GO:0097373;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=25723|UniProtKB=Q86V25 Q86V25 VASH2 PTHR15750:SF4 VASOHIBIN-1-LIKE ISOFORM X2 TUBULINYL-TYR CARBOXYPEPTIDASE 2 regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;regulation of developmental process#GO:0050793;tube morphogenesis#GO:0035239;regulation of vasculature development#GO:1901342;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;vasculature development#GO:0001944;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=14993|UniProtKB=Q8NHC4 Q8NHC4 OR10J5 PTHR24247:SF115 5-HYDROXYTRYPTAMINE RECEPTOR OLFACTORY RECEPTOR 10J5 cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=15341|UniProtKB=Q96R30 Q96R30 OR2V2 PTHR26453:SF235 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2V2 transmembrane signal receptor#PC00197 HUMAN|HGNC=7640|UniProtKB=Q99733 Q99733 NAP1L4 PTHR11875:SF75 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 4 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;organelle organization#GO:0006996;chromosome organization#GO:0051276;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=20510|UniProtKB=P62805 P62805 H4-16 PTHR10484:SF194 HISTONE H4 HISTONE H4 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=12892|UniProtKB=Q9UJU3 Q9UJU3 ZNF112 PTHR24376:SF90 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 112 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=10672|UniProtKB=P48061 P48061 CXCL12 PTHR18837:SF3 STROMAL CELL-DERIVED FACTOR 1 STROMAL CELL-DERIVED FACTOR 1 Axon guidance mediated by Slit/Robo#P00008>Sdf1#P00346 HUMAN|HGNC=8522|UniProtKB=P32243 P32243 OTX2 PTHR45793:SF2 HOMEOBOX PROTEIN HOMEOBOX PROTEIN OTX2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=2345|UniProtKB=P16220 P16220 CREB1 PTHR45879:SF1 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 p38 MAPK pathway#P05918>CREB#P06027;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Enkephalin release#P05913>CREB#P05971;Apoptosis signaling pathway#P00006>ATF#P00302;CCKR signaling map#P06959>CREB1#P07232;Gonadotropin-releasing hormone receptor pathway#P06664>CREB#P06749;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 HUMAN|HGNC=18682|UniProtKB=Q9H0S4 Q9H0S4 DDX47 PTHR24031:SF78 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX47-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=18403|UniProtKB=Q8IZU1 Q8IZU1 FAM9A PTHR19368:SF16 XLR/SCP3/FAM9 PROTEIN FAM9A male gamete generation#GO:0048232;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;spermatid differentiation#GO:0048515;cell differentiation#GO:0030154;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;meiotic cell cycle#GO:0051321;multicellular organism reproduction#GO:0032504;cellular component organization#GO:0016043;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;cell cycle#GO:0007049 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=23699|UniProtKB=Q8NHS0 Q8NHS0 DNAJB8 PTHR43948:SF9 FAMILY NOT NAMED DNAJ HOMOLOG SUBFAMILY B MEMBER 8 HUMAN|HGNC=16788|UniProtKB=Q9BZQ2 Q9BZQ2 SHCBP1L PTHR14695:SF7 SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED TESTICULAR SPINDLE-ASSOCIATED PROTEIN SHCBP1L male gamete generation#GO:0048232;cell division#GO:0051301;gamete generation#GO:0007276;membrane fission#GO:0090148;cellular process involved in reproduction in multicellular organism#GO:0022412;membrane organization#GO:0061024;multicellular organism reproduction#GO:0032504;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;cytoskeleton-dependent cytokinesis#GO:0061640;reproductive process#GO:0022414;cell cycle#GO:0007049;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;male meiotic nuclear division#GO:0007140;multi-organism reproductive process#GO:0044703;cytokinesis#GO:0000910;multicellular organismal reproductive process#GO:0048609 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819 HUMAN|HGNC=33455|UniProtKB=A6NIM6 A6NIM6 SLC15A5 PTHR11654:SF91 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 5 transporter#PC00227 HUMAN|HGNC=4595|UniProtKB=Q14832 Q14832 GRM3 PTHR24060:SF160 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 3 adenylate cyclase activity#GO:0004016;amino acid binding#GO:0016597;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;carboxylic acid binding#GO:0031406;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;glutamate binding#GO:0016595 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Ionotropic glutamate receptor pathway#P00037>mGluR 2/3#P01014;Metabotropic glutamate receptor group II pathway#P00040>mGluR2/3#P01048;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=6962|UniProtKB=P49901 P49901 SMCP PTHR35820:SF1 SPERM MITOCHONDRIAL-ASSOCIATED CYSTEINE-RICH PROTEIN SPERM MITOCHONDRIAL-ASSOCIATED CYSTEINE-RICH PROTEIN HUMAN|HGNC=21240|UniProtKB=Q8N878 Q8N878 FRMD1 PTHR13429:SF7 FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY FERM DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;activating transcription factor binding#GO:0033613;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;hippo signaling#GO:0035329;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 leaflet of membrane bilayer#GO:0097478;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;cytoplasmic side of membrane#GO:0098562 HUMAN|HGNC=16014|UniProtKB=Q96PB1 Q96PB1 CASD1 PTHR13533:SF41 N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE acetyltransferase#PC00038 HUMAN|HGNC=31422|UniProtKB=Q5VTT2 Q5VTT2 C9orf135 PTHR35069:SF1 PROTEIN C9ORF135 PROTEIN C9ORF135 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=28567|UniProtKB=Q8N1D5 Q8N1D5 C1orf158 PTHR31180:SF2 UNCHARACTERIZED HYPOTHETICAL PROTEIN LOC691162 HUMAN|HGNC=17228|UniProtKB=Q9Y620 Q9Y620 RAD54B PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED HUMAN|HGNC=28243|UniProtKB=Q3KRA9 Q3KRA9 ALKBH6 PTHR46030:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6 oxygenase#PC00177 HUMAN|HGNC=28320|UniProtKB=Q8TAP8 Q8TAP8 PPP1R35 PTHR28625:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;negative regulation of phosphatase activity#GO:0010923;negative regulation of phosphorus metabolic process#GO:0010563;regulation of phosphatase activity#GO:0010921;regulation of dephosphorylation#GO:0035303;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of catalytic activity#GO:0050790;negative regulation of dephosphorylation#GO:0035305;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of hydrolase activity#GO:0051336;negative regulation of catalytic activity#GO:0043086;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 phosphatase modulator#PC00184 HUMAN|HGNC=24991|UniProtKB=Q9UNZ5 Q9UNZ5 C19orf53 PTHR16967:SF1 LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG HUMAN|HGNC=2529|UniProtKB=P07339 P07339 CTSD PTHR47966:SF42 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED CATHEPSIN D cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3665|UniProtKB=P05230 P05230 FGF1 PTHR11486:SF86 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 1 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 Angiogenesis#P00005>FGF#P00213;FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=5886|UniProtKB=A0A075B6I3 A0A075B6I3 IGLV11-55 PTHR23267:SF360 IMMUNOGLOBULIN LIGHT CHAIN NON-FUNCTIONAL IMMUNOGLOBULIN LAMBDA VARIABLE 11-55-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=16933|UniProtKB=Q96JP0 Q96JP0 FEM1C PTHR24173:SF14 FAMILY NOT NAMED PROTEIN FEM-1 HOMOLOG C macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=7404|UniProtKB=Q93083 Q93083 MT1L PTHR23299:SF48 METALLOTHIONEIN METALLOTHIONEIN-1E-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;transition metal ion homeostasis#GO:0055076;response to metal ion#GO:0010038;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;response to toxic substance#GO:0009636;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=15339|UniProtKB=Q8NGE7 Q8NGE7 OR9K2 PTHR26452:SF318 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=16895|UniProtKB=Q8N6Y2 Q8N6Y2 LRRC17 PTHR24373:SF301 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 17 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=1069|UniProtKB=P12643 P12643 BMP2 PTHR11848:SF143 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 2 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;receptor serine/threonine kinase binding#GO:0033612 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;positive regulation of protein modification process#GO:0031401;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of cellular protein metabolic process#GO:0032270;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817;TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=30011|UniProtKB=Q9BQY4 Q9BQY4 RHOXF2 PTHR24329:SF540 HOMEOBOX PROTEIN ARISTALESS RHOX HOMEOBOX FAMILY MEMBER 2-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=2681|UniProtKB=Q9UER7 Q9UER7 DAXX PTHR12766:SF7 DEATH DOMAIN-ASSOCIATED PROTEIN 6 DAXX DEATH DOMAIN-ASSOCIATED PROTEIN 6 FAS signaling pathway#P00020>DAXX#P00602;Apoptosis signaling pathway#P00006>DAXX#P00296 HUMAN|HGNC=33609|UniProtKB=A6NNE9 A6NNE9 MARCHF11 PTHR46053:SF1 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF11 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=28989|UniProtKB=Q92617 Q92617 NPIPB3 PTHR15438:SF5 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER B11-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28632|UniProtKB=Q8N988 Q8N988 ZNF557 PTHR24381:SF145 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 557 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=12412|UniProtKB=Q13885 Q13885 TUBB2A PTHR11588:SF100 TUBULIN TUBULIN BETA-2A CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;nuclear division#GO:0000280;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron migration#GO:0001764;movement of cell or subcellular component#GO:0006928;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;generation of neurons#GO:0048699;cell migration#GO:0016477;locomotion#GO:0040011 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 HUMAN|HGNC=3602|UniProtKB=Q9UBX5 Q9UBX5 FBLN5 PTHR24034:SF107 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-5 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;extracellular structure organization#GO:0043062;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix structural protein#PC00103 HUMAN|HGNC=4535|UniProtKB=Q9NQS5 Q9NQS5 GPR84 PTHR24230:SF59 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 84 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=20343|UniProtKB=Q9P0R6 Q9P0R6 GSKIP PTHR12490:SF4 UNCHARACTERIZED GSK3B-INTERACTING PROTEIN protein kinase A binding#GO:0051018;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;molecular function regulator#GO:0098772;kinase activity#GO:0016301;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=17363|UniProtKB=Q8IY57 Q8IY57 YAF2 PTHR12920:SF2 RYBP AND YAF2-RELATED YY1-ASSOCIATED FACTOR 2 nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=9766|UniProtKB=P51159 P51159 RAB27A PTHR47977:SF20 LD21953P-RELATED RAS-RELATED PROTEIN RAB-27A vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;pigmentation#GO:0043473;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;positive regulation of exocytosis#GO:0045921;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;establishment of vesicle localization#GO:0051650;vesicle organization#GO:0016050;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;vesicle localization#GO:0051648;positive regulation of secretion#GO:0051047;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;positive regulation of secretion by cell#GO:1903532;export from cell#GO:0140352 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=27230|UniProtKB=Q56NI9 Q56NI9 ESCO2 PTHR45884:SF3 N-ACETYLTRANSFERASE ECO N-ACETYLTRANSFERASE ESCO2 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;sister chromatid cohesion#GO:0007062;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;DNA biosynthetic process#GO:0071897;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;protein acetylation#GO:0006473;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of DNA replication#GO:0006275;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 acetyltransferase#PC00038 HUMAN|HGNC=3625|UniProtKB=O75636 O75636 FCN3 PTHR19143:SF415 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-3 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=20059|UniProtKB=Q8TEY7 Q8TEY7 USP33 PTHR21646:SF32 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 33 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=4224|UniProtKB=O60383 O60383 GDF9 PTHR11848:SF19 TGF-BETA FAMILY GROWTH/DIFFERENTIATION FACTOR 9 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=33841|UniProtKB=Q495Y8 Q495Y8 SPDYE2 PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=842|UniProtKB=Q06055 Q06055 ATP5MC2 PTHR10031:SF31 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C2, MITOCHONDRIAL cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide biosynthetic process#GO:0009152 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 HUMAN|HGNC=34442|UniProtKB=A6NJI1 A6NJI1 C11orf86 PTHR31831:SF1 HYPOTHETICAL PROTEIN LOC689065 HYPOTHETICAL PROTEIN LOC689065 HUMAN|HGNC=2148|UniProtKB=P29973 P29973 CNGA1 PTHR45638:SF9 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CHANNEL ROD PHOTORECEPTOR SUBUNIT ALPHA cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;inorganic molecular entity transmembrane transporter activity#GO:0015318;nucleotide binding#GO:0000166;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;purine nucleotide binding#GO:0017076;gated channel activity#GO:0022836;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 ligand-gated ion channel#PC00141 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 HUMAN|HGNC=18149|UniProtKB=Q9NPC4 Q9NPC4 A4GALT PTHR12042:SF17 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;sphingolipid biosynthetic process#GO:0030148;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=27963|UniProtKB=A1A519 A1A519 FAM170A PTHR33517:SF3 PROTEIN FAM170B-RELATED PROTEIN FAM170A positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10648|UniProtKB=Q12904 Q12904 AIMP1 PTHR11586:SF33 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1 translational protein#PC00263 HUMAN|HGNC=4652|UniProtKB=P35269 P35269 GTF2F1 PTHR13011:SF0 TFIIF-ALPHA GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1 basal RNA polymerase II transcription machinery binding#GO:0001099;transcription regulator activity#GO:0140110;binding#GO:0005488;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;basal transcription machinery binding#GO:0001098;transcription factor binding#GO:0008134;RNA polymerase II general transcription initiation factor activity#GO:0016251 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;transcription elongation from RNA polymerase II promoter#GO:0006368;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TFIIFalpha#P00663;Transcription regulation by bZIP transcription factor#P00055>TFIIFalpha#P01391 HUMAN|HGNC=19437|UniProtKB=Q9NPC3 Q9NPC3 CCNB1IP1 PTHR14305:SF0 E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1 E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9312|UniProtKB=Q14738 Q14738 PPP2R5D PTHR10257:SF89 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT DELTA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;protein autophosphorylation#GO:0046777;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 HUMAN|HGNC=10542|UniProtKB=O95248 O95248 SBF1 PTHR10807:SF43 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 5 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;phosphoric ester hydrolase activity#GO:0042578;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137;Ras GTPase binding#GO:0017016;hydrolase activity#GO:0016787;Ras guanyl-nucleotide exchange factor activity#GO:0005088;molecular function regulator#GO:0098772;protein binding#GO:0005515;Rab guanyl-nucleotide exchange factor activity#GO:0017112 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=15848|UniProtKB=Q14141 Q14141 SEPTIN6 PTHR18884:SF55 SEPTIN SEPTIN-6 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;cell division#GO:0051301;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;cytokinesis#GO:0000910;membrane fission#GO:0090148;vesicle localization#GO:0051648;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;cell cycle#GO:0007049 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 HUMAN|HGNC=18625|UniProtKB=Q9NWM8 Q9NWM8 FKBP14 PTHR46222:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP14 chaperone#PC00072 HUMAN|HGNC=30766|UniProtKB=Q9Y228 Q9Y228 TRAF3IP3 PTHR15715:SF21 CENTROSOMAL PROTEIN OF 170 KDA TRAF3-INTERACTING JNK-ACTIVATING MODULATOR scaffold/adaptor protein#PC00226 HUMAN|HGNC=2927|UniProtKB=Q14565 Q14565 DMC1 PTHR22942:SF30 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER MEIOTIC RECOMBINATION PROTEIN DMC1/LIM15 HOMOLOG nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;DNA-dependent ATPase activity#GO:0008094;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;telophase#GO:0051326;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;M phase#GO:0000279;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;response to radiation#GO:0009314;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;response to abiotic stimulus#GO:0009628;cell cycle phase#GO:0022403;meiosis I#GO:0007127;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;response to ionizing radiation#GO:0010212;cellular protein-containing complex assembly#GO:0034622;meiosis I cell cycle phase#GO:0098764;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 HUMAN|HGNC=1004|UniProtKB=Q4VC05 Q4VC05 BCL7A PTHR12767:SF11 BCL7 RELATED B-CELL CLL/LYMPHOMA 7 PROTEIN FAMILY MEMBER A HUMAN|HGNC=4440|UniProtKB=P13224 P13224 GP1BB PTHR22650:SF7 GLYCOPROTEIN IB BETA PLATELET GLYCOPROTEIN IB BETA CHAIN Blood coagulation#P00011>GP 1bbeta#P00436 HUMAN|HGNC=8792|UniProtKB=Q9NP56 Q9NP56 PDE7B PTHR11347:SF72 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 7B hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 HUMAN|HGNC=16785|UniProtKB=Q5T5J6 Q5T5J6 SWT1 PTHR16161:SF0 UNCHARACTERIZED TRANSCRIPTIONAL PROTEIN SWT1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=2538|UniProtKB=O60911 O60911 CTSV PTHR12411:SF861 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L2 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=18094|UniProtKB=Q30KQ7 Q30KQ7 DEFB113 PTHR39411:SF1 BETA-DEFENSIN 113 BETA-DEFENSIN 113 antimicrobial response protein#PC00051 HUMAN|HGNC=8039|UniProtKB=P30989 P30989 NTSR1 PTHR24243:SF9 G-PROTEIN COUPLED RECEPTOR NEUROTENSIN RECEPTOR TYPE 1 G-protein coupled receptor#PC00021 HUMAN|HGNC=9604|UniProtKB=P23219 P23219 PTGS1 PTHR11903:SF6 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G/H SYNTHASE 1 oxygenase#PC00177 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cyclooxygenase#P00845 HUMAN|HGNC=6572|UniProtKB=O95970 O95970 LGI1 PTHR24367:SF17 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH GLIOMA-INACTIVATED PROTEIN 1 HUMAN|HGNC=7000|UniProtKB=O00470 O00470 MEIS1 PTHR11850:SF126 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;gene expression#GO:0010467;positive regulation of cell population proliferation#GO:0008284;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;central nervous system development#GO:0007417;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;head development#GO:0060322;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;visual system development#GO:0150063;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=22985|UniProtKB=Q8TAA3 Q8TAA3 PSMA8 PTHR11599:SF144 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA-TYPE 8 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome core complex, alpha-subunit complex#GO:0019773;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=11993|UniProtKB=O95985 O95985 TOP3B PTHR11390:SF20 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-BETA-1 nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;chromosome organization#GO:0051276;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 HUMAN|HGNC=26065|UniProtKB=Q96BS2 Q96BS2 TESC PTHR46823:SF2 CALCINEURIN B HOMOLOGOUS PROTEIN 3 CALCINEURIN B HOMOLOGOUS PROTEIN 3 HUMAN|HGNC=8848|UniProtKB=O00541 O00541 PES1 PTHR12221:SF8 PESCADILLO - RELATED PESCADILLO HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 HUMAN|HGNC=28250|UniProtKB=Q6P1W5 Q6P1W5 C1orf94 PTHR35674:SF1 CDNA SEQUENCE CK137956 CDNA SEQUENCE CK137956 HUMAN|HGNC=14668|UniProtKB=Q495T6 Q495T6 MMEL1 PTHR11733:SF141 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED MEMBRANE METALLO-ENDOPEPTIDASE-LIKE 1 metalloprotease#PC00153 HUMAN|HGNC=28969|UniProtKB=Q14154 Q14154 DELE1 PTHR45011:SF1 DAP3-BINDING CELL DEATH ENHANCER 1 DAP3-BINDING CELL DEATH ENHANCER 1 HUMAN|HGNC=25035|UniProtKB=Q5VVQ6 Q5VVQ6 YOD1 PTHR13312:SF0 HIV-INDUCED PROTEIN-7-LIKE PROTEASE UBIQUITIN THIOESTERASE OTU1 thiol-dependent ubiquitin-specific protease activity#GO:0004843;hydrolase activity#GO:0016787;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;ubiquitin-dependent ERAD pathway#GO:0030433;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=1090|UniProtKB=Q03001 Q03001 DST PTHR23169:SF24 ENVOPLAKIN DYSTONIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule cytoskeleton organization#GO:0000226;wound healing#GO:0042060;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;cell-substrate junction assembly#GO:0007044;response to wounding#GO:0009611;response to stress#GO:0006950;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cell junction organization#GO:0034330;cytoskeleton organization#GO:0007010;cell junction assembly#GO:0034329;intermediate filament cytoskeleton organization#GO:0045104;cytoplasmic microtubule organization#GO:0031122 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;anchoring junction#GO:0070161;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856 intermediate filament binding protein#PC00130 HUMAN|HGNC=15546|UniProtKB=Q96KT7 Q96KT7 SLC35G5 PTHR22911:SF32 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G3-RELATED intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=13594|UniProtKB=Q96FV3 Q96FV3 TSPAN17 PTHR19282:SF470 TETRASPANIN TETRASPANIN-17 protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=10631|UniProtKB=Q8NHW4 Q8NHW4 CCL4L1 PTHR12015:SF103 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 4-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=5301|UniProtKB=P50406 P50406 HTR6 PTHR24247:SF236 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 6 cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=29912|UniProtKB=Q13137 Q13137 CALCOCO2 PTHR31915:SF4 SKICH DOMAIN-CONTAINING PROTEIN CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=25189|UniProtKB=Q96BT7 Q96BT7 ALKBH8 PTHR13069:SF21 UNCHARACTERIZED ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 HUMAN|HGNC=28526|UniProtKB=Q5NDL2 Q5NDL2 EOGT PTHR20961:SF126 GLYCOSYLTRANSFERASE EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=11205|UniProtKB=P08047 P08047 SP1 PTHR23235:SF16 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 Huntington disease#P00029>Sp1#P00803;CCKR signaling map#P06959>SP1#P07203;Gonadotropin-releasing hormone receptor pathway#P06664>SP1#P06846 HUMAN|HGNC=14255|UniProtKB=P55201 P55201 BRPF1 PTHR13793:SF85 PHD FINGER PROTEINS PEREGRIN transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein binding#GO:0005515;histone binding#GO:0042393;N-acyltransferase activity#GO:0016410 histone H3 acetylation#GO:0043966;peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 zinc finger transcription factor#PC00244 HUMAN|HGNC=407|UniProtKB=P30837 P30837 ALDH1B1 PTHR11699:SF207 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE X, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=9757|UniProtKB=Q15032 Q15032 R3HDM1 PTHR15672:SF12 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN R3H DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=8066|UniProtKB=P37198 P37198 NUP62 PTHR12084:SF12 NUCLEAR PORE GLYCOPROTEIN P62-RELATED NUCLEAR PORE GLYCOPROTEIN P62 lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;structural molecule activity#GO:0005198;phospholipid binding#GO:0005543;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear pore central transport channel#GO:0044613;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=24084|UniProtKB=Q2M3G4 Q2M3G4 SHROOM1 PTHR15012:SF37 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cortical cytoskeleton#GO:0030863;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;apical junction complex#GO:0043296 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=2263|UniProtKB=Q7KZN9 Q7KZN9 COX15 PTHR23289:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HOMOLOG chaperone#PC00072 Vitamin D metabolism and pathway#P04396>FDX#P04607 HUMAN|HGNC=4922|UniProtKB=P19367 P19367 HK1 PTHR19443:SF10 HEXOKINASE HEXOKINASE-1 transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;cellular homeostasis#GO:0019725;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;chemical homeostasis#GO:0048878;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;cellular chemical homeostasis#GO:0055082;glycolytic process#GO:0006096;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 Pentose phosphate pathway#P02762>Hexokinase#P03079;Glycolysis#P00024>Hexokinase#P00677;Fructose galactose metabolism#P02744>Hexokinase#P02966 HUMAN|HGNC=30255|UniProtKB=Q9Y255 Q9Y255 PRELID1 PTHR11158:SF31 MSF1/PX19 RELATED PRELI DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL binding#GO:0005488;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 HUMAN|HGNC=30909|UniProtKB=Q6UXR4 Q6UXR4 SERPINA13P PTHR11461:SF20 SERINE PROTEASE INHIBITOR, SERPIN SERPIN A13-RELATED serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>alpha2-antiplasmin#P00428;Plasminogen activating cascade#P00050>alpha2 antiplasmin#P01264;Blood coagulation#P00011>ATIII#P00440 HUMAN|HGNC=587|UniProtKB=P27695 P27695 APEX1 PTHR22748:SF6 AP ENDONUCLEASE DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 3'-5'-exodeoxyribonuclease activity#GO:0008296;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;exodeoxyribonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;exodeoxyribonuclease activity, producing 5'-phosphomonoesters#GO:0016895;phosphoric ester hydrolase activity#GO:0042578;deoxyribonuclease activity#GO:0004536 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 HUMAN|HGNC=4829|UniProtKB=P02042 P02042 HBD PTHR11442:SF50 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT DELTA small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;intracellular#GO:0005622;extracellular region#GO:0005576 HUMAN|HGNC=4926|UniProtKB=O15212 O15212 PFDN6 PTHR21431:SF0 PREFOLDIN SUBUNIT 6 PREFOLDIN SUBUNIT 6 protein binding#GO:0005515;binding#GO:0005488;chaperone binding#GO:0051087 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein folding#GO:0006457;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=14546|UniProtKB=Q9NRJ7 Q9NRJ7 PCDHB16 PTHR24028:SF71 CADHERIN-87A PROTOCADHERIN BETA-16 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=28383|UniProtKB=Q8N7B1 Q8N7B1 HORMAD2 PTHR48225:SF6 HORMA DOMAIN-CONTAINING PROTEIN 1 HORMA DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=8869|UniProtKB=Q99471 Q99471 PFDN5 PTHR12674:SF6 PREFOLDIN SUBUNIT 5 PREFOLDIN SUBUNIT 5 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=4963|UniProtKB=P30511 P30511 HLA-F PTHR16675:SF187 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN F protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;amide binding#GO:0033218;peptide binding#GO:0042277 immune response#GO:0006955;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;T cell mediated immunity#GO:0002456;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=4937|UniProtKB=P13765 P13765 HLA-DOB PTHR19944:SF43 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DO BETA CHAIN major histocompatibility complex protein#PC00149 HUMAN|HGNC=17433|UniProtKB=Q99653 Q99653 CHP1 PTHR46002:SF1 EG:114D9.1 PROTEIN-RELATED CALCINEURIN B HOMOLOGOUS PROTEIN 1 HUMAN|HGNC=8696|UniProtKB=Q9Y5H4 Q9Y5H4 PCDHGA1 PTHR24028:SF108 CADHERIN-87A PROTOCADHERIN GAMMA-A1 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=6871|UniProtKB=P28482 P28482 MAPK1 PTHR24055:SF203 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 1 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>MAPK1#P07166;CCKR signaling map#P06959>MAPK1/3#P07228;EGF receptor signaling pathway#P00018>ERK1-2#P00543;B cell activation#P00010>ERK#P00371;VEGF signaling pathway#P00056>MEK#P01402;Toll receptor signaling pathway#P00054>ERK2#P01356;Interleukin signaling pathway#P00036>ERK#P00965;PDGF signaling pathway#P00047>ERK#P01143;FGF signaling pathway#P00021>ERK1-2#P00627;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MAPK#P05937;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Angiogenesis#P00005>Erk#P00203;VEGF signaling pathway#P00056>Erk#P01407;Apoptosis signaling pathway#P00006>MAPK#P00269;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;T cell activation#P00053>ERK#P01300;Integrin signalling pathway#P00034>ERK#P00907;Angiogenesis#P00005>MEK#P00225;Gonadotropin-releasing hormone receptor pathway#P06664>ERK1/2#P06786;Ras Pathway#P04393>ERK#P04542;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Parkinson disease#P00049>ERK#P01211;Endothelin signaling pathway#P00019>ERK#P00566 HUMAN|HGNC=13831|UniProtKB=Q9BZH6 Q9BZH6 WDR11 PTHR14593:SF5 WD REPEAT-CONTAINING PROTEIN 11 WD REPEAT-CONTAINING PROTEIN 11 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=14111|UniProtKB=Q9HC38 Q9HC38 GLOD4 PTHR46466:SF1 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=1399|UniProtKB=P54289 P54289 CACNA2D1 PTHR10166:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;sarcolemma#GO:0042383;voltage-gated calcium channel complex#GO:0005891;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>Ca2+ channel#P01081 HUMAN|HGNC=4267|UniProtKB=Q92847 Q92847 GHSR PTHR24243:SF7 G-PROTEIN COUPLED RECEPTOR GROWTH HORMONE SECRETAGOGUE RECEPTOR TYPE 1 G-protein coupled receptor#PC00021 HUMAN|HGNC=49178|UniProtKB=H0Y7S4 H0Y7S4 PRAMEF26 PTHR14224:SF100 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 11-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2217|UniProtKB=P20849 P20849 COL9A1 PTHR24023:SF918 COLLAGEN ALPHA COLLAGEN ALPHA-1(IX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;basement membrane#GO:0005604;extracellular region#GO:0005576;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;supramolecular polymer#GO:0099081 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=7613|UniProtKB=P52179 P52179 MYOM1 PTHR13817:SF16 TITIN MYOMESIN-1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=20460|UniProtKB=Q8N5D6 Q8N5D6 GBGT1 PTHR10462:SF49 GLYCOSYLTRANSFERASE-RELATED GLOBOSIDE ALPHA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=18911|UniProtKB=Q9BYQ6 Q9BYQ6 KRTAP4-11 PTHR23262:SF160 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-11 HUMAN|HGNC=16284|UniProtKB=Q9C019 Q9C019 TRIM15 PTHR24103:SF259 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 15 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=3365|UniProtKB=O75355 O75355 ENTPD3 PTHR11782:SF38 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3 nucleotide phosphatase#PC00173 HUMAN|HGNC=2522|UniProtKB=Q6GPI1 Q6GPI1 CTRB2 PTHR24250:SF53 CHYMOTRYPSIN-RELATED CHYMOTRYPSINOGEN B2 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203 HUMAN|HGNC=16088|UniProtKB=Q6P4A7 Q6P4A7 SFXN4 PTHR11153:SF3 SIDEROFLEXIN SIDEROFLEXIN-4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;transmembrane transport#GO:0055085;cellular process#GO:0009987;establishment of localization#GO:0051234;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068 HUMAN|HGNC=17432|UniProtKB=Q9BZP6 Q9BZP6 CHIA PTHR11177:SF188 CHITINASE ACIDIC MAMMALIAN CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;carbohydrate derivative binding#GO:0097367;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;binding#GO:0005488;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110 HUMAN|HGNC=19818|UniProtKB=Q9H329 Q9H329 EPB41L4B PTHR23280:SF18 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 4B HUMAN|HGNC=16699|UniProtKB=Q9UPU3 Q9UPU3 SORCS3 PTHR12106:SF10 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS3 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810 cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;integral component of membrane#GO:0016021;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=19612|UniProtKB=Q8NH18 Q8NH18 OR5J2 PTHR26452:SF418 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5J2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=10663|UniProtKB=O60524 O60524 NEMF PTHR15239:SF6 NUCLEAR EXPORT MEDIATOR FACTOR NEMF NUCLEAR EXPORT MEDIATOR FACTOR NEMF tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991 HUMAN|HGNC=29850|UniProtKB=O75113 O75113 N4BP1 PTHR12876:SF26 N4BP1-RELATED NEDD4-BINDING PROTEIN 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endoribonuclease activity#GO:0004521;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular nitrogen compound metabolic process#GO:0034641;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;negative regulation of protein ubiquitination#GO:0031397;regulation of cellular process#GO:0050794;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of protein catabolic process#GO:0042177;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;negative regulation of proteasomal protein catabolic process#GO:1901799;organic cyclic compound metabolic process#GO:1901360;negative regulation of proteolysis involved in cellular protein catabolic process#GO:1903051;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;heterocycle metabolic process#GO:0046483;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular catabolic process#GO:0031330;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein catabolic process#GO:1903363;negative regulation of catabolic process#GO:0009895;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;PML body#GO:0016605 endoribonuclease#PC00094 HUMAN|HGNC=1384|UniProtKB=Q9NZU7 Q9NZU7 CABP1 PTHR45917:SF1 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 1 HUMAN|HGNC=18902|UniProtKB=Q9BYQ2 Q9BYQ2 KRTAP9-4 PTHR23262:SF32 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-2-RELATED HUMAN|HGNC=17870|UniProtKB=Q9Y283 Q9Y283 INVS PTHR24178:SF2 MOLTING PROTEIN MLT-4 INVERSIN protein localization to plasma membrane#GO:0072659;blood circulation#GO:0008015;cellular localization#GO:0051641;regulation of multicellular organismal process#GO:0051239;regulation of muscle contraction#GO:0006937;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;regulation of heart contraction#GO:0008016;system process#GO:0003008;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;regulation of system process#GO:0044057;cellular process#GO:0009987;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;protein localization to organelle#GO:0033365;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990;sarcolemma#GO:0042383;plasma membrane#GO:0005886 HUMAN|HGNC=25238|UniProtKB=Q8NHG7 Q8NHG7 SVIP PTHR35269:SF1 SMALL VCP/P97-INTERACTING PROTEIN SMALL VCP/P97-INTERACTING PROTEIN negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;negative regulation of cellular component organization#GO:0051129;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;ERAD pathway#GO:0036503;negative regulation of transport#GO:0051051;response to organonitrogen compound#GO:0010243;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;peptide transport#GO:0015833;regulation of cellular localization#GO:0060341;negative regulation of nitrogen compound metabolic process#GO:0051172;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;regulation of cellular process#GO:0050794;protein transport#GO:0015031;positive regulation of catabolic process#GO:0009896;intracellular transport#GO:0046907;positive regulation of autophagy#GO:0010508;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of establishment of protein localization#GO:0070201;regulation of metabolic process#GO:0019222;regulation of peptide transport#GO:0090087;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;negative regulation of protein catabolic process#GO:0042177;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;transport#GO:0006810;protein-containing complex assembly#GO:0065003;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;amide transport#GO:0042886;process utilizing autophagic mechanism#GO:0061919;negative regulation of proteasomal protein catabolic process#GO:1901799;organic substance transport#GO:0071702;regulation of transport#GO:0051049;regulation of protein-containing complex assembly#GO:0043254;positive regulation of metabolic process#GO:0009893;negative regulation of proteolysis involved in cellular protein catabolic process#GO:1903051;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of protein transport#GO:0051223;regulation of cellular protein catabolic process#GO:1903362;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of autophagy#GO:0010506;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;regulation of response to stress#GO:0080134;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;localization#GO:0051179;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of catabolic process#GO:0009895;negative regulation of cellular protein catabolic process#GO:1903363;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;ubiquitin-dependent ERAD pathway#GO:0030433;establishment of localization in cell#GO:0051649;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;anchored component of membrane#GO:0031225;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=15755|UniProtKB=Q9P1A2 Q9P1A2 PPP4R1L PTHR10648:SF9 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 65 KDA REGULATORY SUBUNIT A BETA ISOFORM-RELATED phosphatase binding#GO:0019902;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;protein serine/threonine phosphatase activity#GO:0004722;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 HUMAN|HGNC=16951|UniProtKB=Q9Y6Y0 Q9Y6Y0 IVNS1ABP PTHR24412:SF396 KELCH PROTEIN INFLUENZA VIRUS NS1A-BINDING PROTEIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=28029|UniProtKB=Q49AJ0 Q49AJ0 FAM135B PTHR12482:SF3 UNCHARACTERIZED PROTEIN FAM135B lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 HUMAN|HGNC=15814|UniProtKB=Q9NR19 Q9NR19 ACSS2 PTHR24095:SF126 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE, CYTOPLASMIC ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 HUMAN|HGNC=33131|UniProtKB=Q6NUJ1 Q6NUJ1 PSAPL1 PTHR11480:SF39 SAPOSIN-RELATED PROACTIVATOR POLYPEPTIDE-LIKE 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 HUMAN|HGNC=1964|UniProtKB=P30926 P30926 CHRNB4 PTHR18945:SF385 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNB4#P06610;Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=2408|UniProtKB=P11844 P11844 CRYGA PTHR11818:SF123 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN A structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=28662|UniProtKB=Q9BU89 Q9BU89 DOHH PTHR12697:SF5 PBS LYASE HEAT-LIKE PROTEIN DEOXYHYPUSINE HYDROXYLASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lyase#PC00144 HUMAN|HGNC=14621|UniProtKB=Q9BZD4 Q9BZD4 NUF2 PTHR21650:SF2 MEMBRALIN/KINETOCHORE PROTEIN NUF2 KINETOCHORE PROTEIN NUF2 protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular localization#GO:0051641;mitotic spindle organization#GO:0007052;organelle localization#GO:0051640;kinetochore organization#GO:0051383;nuclear division#GO:0000280;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;metaphase plate congression#GO:0051310;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;establishment of organelle localization#GO:0051656;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;establishment of chromosome localization#GO:0051303;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;mitotic metaphase plate congression#GO:0007080;chromosome localization#GO:0050000 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome kinetochore#GO:0000777;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;condensed nuclear chromosome kinetochore#GO:0000778;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=4214|UniProtKB=P27539 P27539 GDF1 PTHR11848:SF151 TGF-BETA FAMILY EMBRYONIC GROWTH/DIFFERENTIATION FACTOR 1 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=10759|UniProtKB=Q9Y6X1 Q9Y6X1 SERP1 PTHR15601:SF14 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN 1 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=4037|UniProtKB=P06241 P06241 FYN PTHR24418:SF44 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FYN protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell population proliferation#GO:0008283;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cell differentiation#GO:0030154;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;peptidyl-tyrosine modification#GO:0018212;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 Axon guidance mediated by semaphorins#P00007>Fyn#P00335;Parkinson disease#P00049>Src kinase#P01230;Cadherin signaling pathway#P00012>Fyn#P00464;Parkinson disease#P00049>Fyn kinase#P01235;Integrin signalling pathway#P00034>Fyn#P00942 HUMAN|HGNC=13586|UniProtKB=Q9Y3I1 Q9Y3I1 FBXO7 PTHR15537:SF2 F-BOX ONLY PROTEIN 7 F-BOX ONLY PROTEIN 7 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 negative regulation of biological process#GO:0048519;positive regulation of organelle organization#GO:0010638;regulation of catabolic process#GO:0009894;regulation of neuron death#GO:1901214;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;regulation of cellular component organization#GO:0051128;neuron death#GO:0070997;autophagy of mitochondrion#GO:0000422;response to oxidative stress#GO:0006979;negative regulation of neuron death#GO:1901215;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;regulation of cellular response to stress#GO:0080135;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;regulation of mitochondrion organization#GO:0010821;cell death#GO:0008219;cellular response to oxidative stress#GO:0034599;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organelle disassembly#GO:1903008;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;response to stimulus#GO:0050896;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell death#GO:0010941;positive regulation of catabolic process#GO:0009896;positive regulation of autophagy#GO:0010508;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=11840|UniProtKB=Q04727 Q04727 TLE4 PTHR10814:SF31 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 4 repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein binding#GO:0005515;molecular function regulator#GO:0098772;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 HUMAN|HGNC=34395|UniProtKB=A6PVY3 A6PVY3 FAM177B PTHR31206:SF9 LP10445P PROTEIN FAM177B HUMAN|HGNC=6283|UniProtKB=Q9NPC2 Q9NPC2 KCNK9 PTHR11003:SF75 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 9 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 Dopamine receptor mediated signaling pathway#P05912>K+ channel#P05957;5HT4 type receptor mediated signaling pathway#P04376>K+ channel#P04426;Nicotine pharmacodynamics pathway#P06587>KCNK3/9#P06605;5HT2 type receptor mediated signaling pathway#P04374>K+ channel#P04413;Opioid proenkephalin pathway#P05915>K+ channel#P05990;5HT1 type receptor mediated signaling pathway#P04373>K+ channel#P04407;Opioid proopiomelanocortin pathway#P05917>K+ channel#P06009;5HT3 type receptor mediated signaling pathway#P04375>K+ channel#P04425 HUMAN|HGNC=5398|UniProtKB=P13284 P13284 IFI30 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198 HUMAN|HGNC=18922|UniProtKB=Q8IUC1 Q8IUC1 KRTAP11-1 PTHR19051:SF14 KERATIN-ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 11-1 structural protein#PC00211 HUMAN|HGNC=33725|UniProtKB=Q6ICI0 Q6ICI0 TMEM211 PTHR12489:SF20 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN TRANSMEMBRANE PROTEIN 211 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=1161|UniProtKB=Q53EZ4 Q53EZ4 CEP55 PTHR31838:SF1 CENTROSOMAL PROTEIN OF 55 KDA CENTROSOMAL PROTEIN OF 55 KDA HUMAN|HGNC=6358|UniProtKB=O43240 O43240 KLK10 PTHR24271:SF66 KALLIKREIN-RELATED KALLIKREIN-10 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=19835|UniProtKB=Q7Z553 Q7Z553 MDGA2 PTHR23282:SF137 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 2 HUMAN|HGNC=15809|UniProtKB=Q9Y3M9 Q9Y3M9 ZNF337 PTHR24381:SF22 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 337 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=10945|UniProtKB=O00341 O00341 SLC1A7 PTHR11958:SF22 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 5 primary active transporter#PC00068 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 HUMAN|HGNC=28880|UniProtKB=Q9H0U3 Q9H0U3 MAGT1 PTHR12692:SF2 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED MAGNESIUM TRANSPORTER PROTEIN 1 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 HUMAN|HGNC=12709|UniProtKB=P12018 P12018 VPREB1 PTHR23267:SF11 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN IOTA CHAIN response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=12713|UniProtKB=P49754 P49754 VPS41 PTHR12616:SF1 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 vesicle fusion#GO:0006906;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;response to extracellular stimulus#GO:0009991;establishment of protein localization#GO:0045184;process utilizing autophagic mechanism#GO:0061919;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular response to starvation#GO:0009267;establishment of localization#GO:0051234;catabolic process#GO:0009056;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;cellular response to extracellular stimulus#GO:0031668;organelle fusion#GO:0048284;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;establishment of protein localization to vacuole#GO:0072666;cellular response to stimulus#GO:0051716;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cell communication#GO:0007154;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;protein transport#GO:0015031;cellular response to external stimulus#GO:0071496;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;autophagy#GO:0006914 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=25006|UniProtKB=Q9NRN9 Q9NRN9 METTL5 PTHR23290:SF0 UNCHARACTERIZED RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5 HUMAN|HGNC=24265|UniProtKB=Q9Y3E5 Q9Y3E5 PTRH2 PTHR12649:SF11 PEPTIDYL-TRNA HYDROLASE 2 PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL HUMAN|Ensembl=ENSG00000283329|UniProtKB=A0A1B0GVZ2 A0A1B0GVZ2 FAM240B PTHR40387:SF1 PROTEIN FAM240B PROTEIN FAM240B HUMAN|HGNC=16006|UniProtKB=Q9H175 Q9H175 CSRNP2 PTHR13580:SF6 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE/SERINE-RICH NUCLEAR PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8221|UniProtKB=Q8NGS0 Q8NGS0 OR1N1 PTHR48001:SF43 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1N1 transmembrane signal receptor#PC00197 HUMAN|HGNC=925|UniProtKB=O60909 O60909 B4GALT2 PTHR19300:SF32 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 2 glycosyltransferase#PC00111 HUMAN|HGNC=7675|UniProtKB=Q99608 Q99608 NDN PTHR11736:SF10 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN NECDIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=52277|UniProtKB=A0A0J9YWL9 A0A0J9YWL9 TEX13C PTHR23111:SF72 ZINC FINGER PROTEIN TESTIS-EXPRESSED PROTEIN 13C-RELATED HUMAN|HGNC=5329|UniProtKB=P10997 P10997 IAPP PTHR10505:SF4 CALCITONIN-RELATED ISLET AMYLOID POLYPEPTIDE peptide hormone#PC00179 HUMAN|HGNC=7506|UniProtKB=O75431 O75431 MTX2 PTHR12289:SF38 METAXIN RELATED METAXIN-2 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=28943|UniProtKB=Q53RY4 Q53RY4 KRTCAP3 PTHR31258:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 3 KERATINOCYTE-ASSOCIATED PROTEIN 3 HUMAN|HGNC=17255|UniProtKB=P50748 P50748 KNTC1 PTHR15688:SF1 KINETOCHORE-ASSOCIATED PROTEIN 1 KINETOCHORE-ASSOCIATED PROTEIN 1 HUMAN|HGNC=16502|UniProtKB=P58872 P58872 RHBDL3 PTHR45840:SF5 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 3 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 HUMAN|HGNC=9502|UniProtKB=Q99418 Q99418 CYTH2 PTHR10663:SF343 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-2 guanyl-nucleotide exchange factor#PC00113 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GEF#P00875 HUMAN|HGNC=24261|UniProtKB=Q9Y3D0 Q9Y3D0 CIAO2B PTHR12377:SF0 UNCHARACTERIZED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular process#GO:0009987;metabolic process#GO:0008152 HUMAN|HGNC=15565|UniProtKB=Q96P65 Q96P65 QRFPR PTHR24241:SF119 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PYROGLUTAMYLATED RF-AMIDE PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=34071|UniProtKB=A6NHN0 A6NHN0 OTOL1 PTHR24023:SF914 COLLAGEN ALPHA OTOLIN-1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;basement membrane#GO:0005604;extracellular region#GO:0005576;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;supramolecular polymer#GO:0099081 extracellular matrix structural protein#PC00103 HUMAN|HGNC=4441|UniProtKB=P55259 P55259 GP2 PTHR14002:SF16 ENDOGLIN/TGF-BETA RECEPTOR TYPE III PANCREATIC SECRETORY GRANULE MEMBRANE MAJOR GLYCOPROTEIN GP2 localization#GO:0051179;leukocyte migration#GO:0050900;granulocyte migration#GO:0097530;immune system process#GO:0002376;myeloid leukocyte migration#GO:0097529;neutrophil migration#GO:1990266;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 cell surface#GO:0009986;extracellular region#GO:0005576;plasma membrane region#GO:0098590;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=31037|UniProtKB=Q7RTY0 Q7RTY0 SLC16A13 PTHR11360:SF19 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 13 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=50507|UniProtKB=A0A1B0GTU2 A0A1B0GTU2 CTXND1 PTHR16736:SF5 CORTEXIN-1-RELATED CORTEXIN DOMAIN-CONTAINING 1 HUMAN|HGNC=24566|UniProtKB=Q5T6S3 Q5T6S3 PHF19 PTHR12628:SF6 POLYCOMB-LIKE TRANSCRIPTION FACTOR PHD FINGER PROTEIN 19 nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=42972|UniProtKB=A6NJI9 A6NJI9 LRRC72 PTHR46759:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72 HUMAN|HGNC=26899|UniProtKB=Q6ZXV5 Q6ZXV5 TMTC3 PTHR44395:SF1 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC3 HUMAN|HGNC=32942|UniProtKB=Q9HB31 Q9HB31 SEBOX PTHR47777:SF1 HOMEOBOX PROTEIN SEBOX HOMEOBOX PROTEIN SEBOX homeodomain transcription factor#PC00119 HUMAN|HGNC=18314|UniProtKB=Q92730 Q92730 RND1 PTHR24072:SF23 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHO6 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948 HUMAN|HGNC=30634|UniProtKB=Q12770 Q12770 SCAP PTHR46378:SF1 STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN HUMAN|HGNC=26147|UniProtKB=Q8NDL9 Q8NDL9 AGBL5 PTHR12756:SF12 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE-LIKE PROTEIN 5 metalloprotease#PC00153 HUMAN|HGNC=19819|UniProtKB=Q9HCM4 Q9HCM4 EPB41L5 PTHR23280:SF15 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 5 HUMAN|HGNC=10705|UniProtKB=P53992 P53992 SEC24C PTHR13803:SF5 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24C cation binding#GO:0043169;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;Golgi vesicle budding#GO:0048194;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=34237|UniProtKB=Q05DH4 Q05DH4 FAM160A1 PTHR21705:SF6 RAI16 PROTEIN-RELATED PROTEIN FAM160A1 HUMAN|HGNC=16475|UniProtKB=Q3SXM5 Q3SXM5 HSDL1 PTHR44889:SF1 INACTIVE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1 INACTIVE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1 dehydrogenase#PC00092 HUMAN|HGNC=9751|UniProtKB=P47897 P47897 QARS1 PTHR43097:SF4 GLUTAMINE-TRNA LIGASE GLUTAMINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 HUMAN|HGNC=26526|UniProtKB=Q96MA6 Q96MA6 AK8 PTHR23359:SF217 NUCLEOTIDE KINASE ADENYLATE KINASE 8 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;adenylate kinase activity#GO:0004017;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;nucleoside diphosphate metabolic process#GO:0009132;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896;Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153 HUMAN|HGNC=17292|UniProtKB=Q8IWA5 Q8IWA5 SLC44A2 PTHR12385:SF34 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 2 ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;choline transport#GO:0015871;organic cation transport#GO:0015695;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;cation transport#GO:0006812;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=7510|UniProtKB=Q9UKN1 Q9UKN1 MUC12 PTHR24041:SF25 MUCIN MUCIN-12 cell adhesion molecule#PC00069 HUMAN|HGNC=9536|UniProtKB=O14818 O14818 PSMA7 PTHR11599:SF40 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-7 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 synapse#GO:0045202;peptidase complex#GO:1905368;proteasome core complex, alpha-subunit complex#GO:0019773;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cell junction#GO:0030054;proteasome complex#GO:0000502;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=12196|UniProtKB=A0A075B6N2 A0A075B6N2 TRBV20-1 PTHR23268:SF11 T-CELL RECEPTOR BETA CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=9769|UniProtKB=O15211 O15211 RGL2 PTHR23113:SF213 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 2 guanyl-nucleotide exchange factor#PC00113 Ras Pathway#P04393>RalGDS#P04551 HUMAN|HGNC=24374|UniProtKB=O43169 O43169 CYB5B PTHR19359:SF132 CYTOCHROME B5 CYTOCHROME B5 TYPE B electron transfer activity#GO:0009055;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 oxidoreductase#PC00176 HUMAN|HGNC=30460|UniProtKB=Q86UT8 Q86UT8 CCDC84 PTHR31198:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 84 COILED-COIL DOMAIN-CONTAINING PROTEIN 84 HUMAN|HGNC=10879|UniProtKB=Q15468 Q15468 STIL PTHR15128:SF0 TAL1 SCL INTERRUPTING LOCUS SCL-INTERRUPTING LOCUS PROTEIN cellular localization#GO:0051641;signal transduction#GO:0007165;mitotic spindle organization#GO:0007052;macromolecule localization#GO:0033036;smoothened signaling pathway#GO:0007224;cellular protein localization#GO:0034613;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;spindle organization#GO:0007051;protein localization to organelle#GO:0033365;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;protein localization to cytoskeleton#GO:0044380;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=18000|UniProtKB=Q7RTV0 Q7RTV0 PHF5A PTHR13120:SF0 PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114;U12-type spliceosomal complex#GO:0005689 HUMAN|HGNC=8050|UniProtKB=O95989 O95989 NUDT3 PTHR12629:SF5 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 1 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleotide diphosphatase activity#GO:0004551;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organophosphate catabolic process#GO:0046434;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphatase#PC00181 HUMAN|HGNC=24763|UniProtKB=Q6ZVT6 Q6ZVT6 CFAP20DC PTHR12458:SF7 ORF PROTEIN PROTEIN CFAP20DC HUMAN|HGNC=14786|UniProtKB=Q8NH54 Q8NH54 OR56A3 PTHR26450:SF40 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56A3 transmembrane signal receptor#PC00197 HUMAN|HGNC=10702|UniProtKB=Q15437 Q15437 SEC23B PTHR11141:SF10 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23B pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;Golgi vesicle budding#GO:0048194;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=16913|UniProtKB=Q9NSA3 Q9NSA3 CTNNBIP1 PTHR47142:SF1 BETA-CATENIN-INTERACTING PROTEIN 1 BETA-CATENIN-INTERACTING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=33721|UniProtKB=Q6GMV1 Q6GMV1 ALG1L PTHR13036:SF3 BETA1,4 MANNOSYLTRANSFERASE GLYCOSYLTRANSFERASE ALG1-LIKE-RELATED transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=7857|UniProtKB=P30419 P30419 NMT1 PTHR11377:SF7 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;protein acylation#GO:0043543;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transferase#PC00220 HUMAN|HGNC=24458|UniProtKB=O94850 O94850 DDN PTHR16757:SF1 DENDRIN DENDRIN HUMAN|HGNC=3287|UniProtKB=P06730 P06730 EIF4E PTHR11960:SF14 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;RNA cap binding#GO:0000339 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 CCKR signaling map#P06959>EIF4E#P07094;p38 MAPK pathway#P05918>eIF4E#P06024 HUMAN|HGNC=2079|UniProtKB=Q9UBY8 Q9UBY8 CLN8 PTHR13439:SF7 CT120 PROTEIN PROTEIN CLN8 biological regulation#GO:0065007;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=13361|UniProtKB=Q9NQ76 Q9NQ76 MEPE PTHR16510:SF4 EXTRACELLULAR MATRIX PHOSPHOGLYCOPROTEIN WITH ASARM MOTIF MATRIX EXTRACELLULAR PHOSPHOGLYCOPROTEIN protein binding#GO:0005515;binding#GO:0005488 system development#GO:0048731;biomineralization#GO:0110148;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;biomineral tissue development#GO:0031214;tissue development#GO:0009888 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=25622|UniProtKB=Q9NUY8 Q9NUY8 TBC1D23 PTHR13297:SF5 UNCHARACTERIZED TBC1 DOMAIN FAMILY MEMBER 23 endosomal transport#GO:0016197;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle targeting#GO:0006903;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=14665|UniProtKB=A6NKG5 A6NKG5 RTL1 PTHR15503:SF9 LDOC1 RELATED RETROTRANSPOSON-LIKE PROTEIN 1 HUMAN|HGNC=9949|UniProtKB=O94761 O94761 RECQL4 PTHR13710:SF108 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q4 pyrophosphatase activity#GO:0016462;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA helicase#PC00011 HUMAN|HGNC=40031|UniProtKB=A6NNT2 A6NNT2 C16orf96 PTHR47080:SF1 CHROMOSOME 16 OPEN READING FRAME 96 CHROMOSOME 16 OPEN READING FRAME 96 HUMAN|HGNC=29030|UniProtKB=O43159 O43159 RRP8 PTHR12787:SF0 UNCHARACTERIZED RIBOSOMAL RNA-PROCESSING PROTEIN 8 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25326|UniProtKB=Q9H0J4 Q9H0J4 QRICH2 PTHR46766:SF1 GLUTAMINE-RICH PROTEIN 2 GLUTAMINE-RICH PROTEIN 2 HUMAN|HGNC=23990|UniProtKB=Q6ZMT1 Q6ZMT1 STAC2 PTHR15135:SF5 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN 2 positive regulation of ion transport#GO:0043270;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of metal ion transport#GO:0010959;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of molecular function#GO:0044093;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;establishment of localization#GO:0051234;skeletal muscle contraction#GO:0003009;regulation of molecular function#GO:0065009;divalent inorganic cation transport#GO:0072511;positive regulation of transmembrane transport#GO:0034764;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;protein localization to plasma membrane#GO:0072659;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;protein localization to membrane#GO:0072657;calcium ion transmembrane transport#GO:0070588;regulation of protein localization to membrane#GO:1905475;ion transport#GO:0006811;regulation of calcium ion transport#GO:0051924;positive regulation of ion transmembrane transporter activity#GO:0032414;positive regulation of transport#GO:0051050;positive regulation of calcium ion transport#GO:0051928;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;striated muscle contraction#GO:0006941;ion transmembrane transport#GO:0034220;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;protein localization to cell periphery#GO:1990778;regulation of ion transmembrane transport#GO:0034765;cellular macromolecule localization#GO:0070727;positive regulation of transporter activity#GO:0032411;regulation of cellular process#GO:0050794;positive regulation of ion transmembrane transport#GO:0034767;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of ion transport#GO:0043269;muscle system process#GO:0003012;muscle contraction#GO:0006936 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 HUMAN|HGNC=5553|UniProtKB=A0A0A0MS14 A0A0A0MS14 IGHV1-45 PTHR23266:SF285 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-45 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=2419|UniProtKB=Q08257 Q08257 CRYZ PTHR44154:SF1 QUINONE OXIDOREDUCTASE QUINONE OXIDOREDUCTASE oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 HUMAN|HGNC=12672|UniProtKB=P45880 P45880 VDAC2 PTHR11743:SF12 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;inorganic anion transmembrane transporter activity#GO:0015103;channel activity#GO:0015267;transporter activity#GO:0005215 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 voltage-gated ion channel#PC00241 HUMAN|HGNC=25459|UniProtKB=Q8N7H5 Q8N7H5 PAF1 PTHR23188:SF12 RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;chromatin binding#GO:0003682;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;enzyme binding#GO:0019899;protein binding#GO:0005515;basal transcription machinery binding#GO:0001098 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=12492|UniProtKB=P61088 P61088 UBE2N PTHR24068:SF152 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 N ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;protein K63-linked ubiquitination#GO:0070534;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Toll receptor signaling pathway#P00054>Ubc13#P01381 HUMAN|HGNC=25915|UniProtKB=Q5U5X8 Q5U5X8 FAM222A PTHR16070:SF2 UNCHARACTERIZED PROTEIN FAM222A HUMAN|HGNC=17144|UniProtKB=Q8TCD5 Q8TCD5 NT5C PTHR16504:SF5 5'(3')-DEOXYRIBONUCLEOTIDASE 5'(3')-DEOXYRIBONUCLEOTIDASE, CYTOSOLIC TYPE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;nucleotidase activity#GO:0008252 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 HUMAN|HGNC=8075|UniProtKB=Q9H1B4 Q9H1B4 NXF5 PTHR10662:SF15 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=29284|UniProtKB=Q9P265 Q9P265 DIP2B PTHR22754:SF38 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG B HUMAN|HGNC=21101|UniProtKB=O60888 O60888 CUTA PTHR23419:SF1 DIVALENT CATION TOLERANCE CUTA-RELATED PROTEIN CUTA copper ion binding#GO:0005507;cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;transition metal ion binding#GO:0046914 primary active transporter#PC00068 HUMAN|HGNC=13094|UniProtKB=Q9Y508 Q9Y508 RNF114 PTHR46016:SF3 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF114 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=7013|UniProtKB=P50221 P50221 MEOX1 PTHR24328:SF8 HOMEOBOX PROTEIN MOX HOMEOBOX PROTEIN MOX-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=13908|UniProtKB=Q96SC8 Q96SC8 DMRTA2 PTHR12322:SF76 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;sex differentiation#GO:0007548;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;reproduction#GO:0000003;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=21084|UniProtKB=Q9P2D6 Q9P2D6 FAM135A PTHR12482:SF40 UNCHARACTERIZED PROTEIN FAM135A lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 HUMAN|HGNC=16903|UniProtKB=Q15025 Q15025 TNIP1 PTHR31882:SF3 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;negative regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043124;positive regulation of transcription, DNA-templated#GO:0045893;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 HUMAN|HGNC=6159|UniProtKB=P56537 P56537 EIF6 PTHR10784:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 6 EUKARYOTIC TRANSLATION INITIATION FACTOR 6 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;ncRNA metabolic process#GO:0034660;ncRNA processing#GO:0034470;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;rRNA metabolic process#GO:0016072;protein transport#GO:0015031;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503;cellular aromatic compound metabolic process#GO:0006725;ribosomal subunit export from nucleus#GO:0000054;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;protein-containing complex assembly#GO:0065003;RNA processing#GO:0006396;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex export from nucleus#GO:0071426;amide transport#GO:0042886;organic substance transport#GO:0071702;organic cyclic compound metabolic process#GO:1901360;protein export from nucleus#GO:0006611;maturation of 5.8S rRNA#GO:0000460;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;ribonucleoprotein complex localization#GO:0071166;cellular process#GO:0009987;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;RNA export from nucleus#GO:0006405;maturation of LSU-rRNA#GO:0000470 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cytosol#GO:0005829;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684 translation initiation factor#PC00224 HUMAN|HGNC=25079|UniProtKB=Q96HJ3 Q96HJ3 CCDC34 PTHR23247:SF2 NY-REN-41 ANTIGEN L15 -RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 34 HUMAN|HGNC=25010|UniProtKB=Q9BVV7 Q9BVV7 TIMM21 PTHR13032:SF6 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=24528|UniProtKB=Q9NZ81 Q9NZ81 PRR13 PTHR36287:SF1 FAMILY NOT NAMED PROLINE-RICH PROTEIN 13 HUMAN|HGNC=8996|UniProtKB=O60331 O60331 PIP5K1C PTHR23086:SF26 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 GAMMA kinase#PC00137 HUMAN|HGNC=25916|UniProtKB=Q5VSL9 Q5VSL9 STRIP1 PTHR13239:SF7 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 STRIATIN-INTERACTING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=18027|UniProtKB=Q3B726 Q3B726 POLR1F PTHR12709:SF5 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=11632|UniProtKB=O43680 O43680 TCF21 PTHR23349:SF67 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 21 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=8615|UniProtKB=P15863 P15863 PAX1 PTHR45636:SF15 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=21035|UniProtKB=Q8N392 Q8N392 ARHGAP18 PTHR14963:SF6 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 18 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;regulation of signaling#GO:0023051;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;intracellular signal transduction#GO:0035556;regulation of protein polymerization#GO:0032271;signaling#GO:0023052;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cellular response to stimulus#GO:0051716;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of small GTPase mediated signal transduction#GO:0051056;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 HUMAN|HGNC=13549|UniProtKB=Q9P241 Q9P241 ATP10D PTHR24092:SF84 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VD-RELATED pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=17865|UniProtKB=Q96A26 Q96A26 FAM162A PTHR13674:SF2 GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN PROTEIN FAM162A neuron apoptotic process#GO:0051402;signal transduction#GO:0007165;response to hypoxia#GO:0001666;positive regulation of organelle organization#GO:0010638;apoptotic mitochondrial changes#GO:0008637;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;neuron death#GO:0070997;regulation of apoptotic signaling pathway#GO:2001233;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of programmed cell death#GO:0043068;regulation of mitochondrion organization#GO:0010821;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;cell death#GO:0008219;positive regulation of apoptotic signaling pathway#GO:2001235;mitochondrion organization#GO:0007005;response to abiotic stimulus#GO:0009628;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to oxygen levels#GO:0070482;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;cellular response to chemical stimulus#GO:0070887;regulation of organelle organization#GO:0033043;response to decreased oxygen levels#GO:0036293;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular response to hypoxia#GO:0071456;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;response to stress#GO:0006950;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell death#GO:0010941;cellular response to stress#GO:0033554;positive regulation of cell death#GO:0010942 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=23846|UniProtKB=Q96BF6 Q96BF6 NACC2 PTHR46105:SF2 AGAP004733-PA NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=51240|UniProtKB=A0JP26 A0JP26 POTEB3 PTHR24118:SF65 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER B-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=25302|UniProtKB=O75208 O75208 COQ9 PTHR21427:SF19 UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL lipid binding#GO:0008289;binding#GO:0005488 cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;small molecule biosynthetic process#GO:0044283;ubiquinone biosynthetic process#GO:0006744;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=24791|UniProtKB=Q3MJ16 Q3MJ16 PLA2G4E PTHR10728:SF24 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 EPSILON hydrolase activity, acting on ester bonds#GO:0016788;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;phospholipid binding#GO:0005543;carboxylic ester hydrolase activity#GO:0052689;cation binding#GO:0043169;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;hydrolase activity#GO:0016787;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phospholipase#PC00186 HUMAN|HGNC=3973|UniProtKB=O95633 O95633 FSTL3 PTHR10913:SF16 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 3 protein-containing complex binding#GO:0044877;activin binding#GO:0048185;binding#GO:0005488 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=24913|UniProtKB=Q49AH0 Q49AH0 CDNF PTHR12990:SF9 ARMET-LIKE PROTEIN CEREBRAL DOPAMINE NEUROTROPHIC FACTOR cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=2411|UniProtKB=P07320 P07320 CRYGD PTHR11818:SF119 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN D structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=44201|UniProtKB=P0DKL9 P0DKL9 ARL14EPL PTHR46804:SF4 ADP RIBOSYLATION FACTOR LIKE GTPASE 14 EFFECTOR PROTEIN LIKE ARL14 EFFECTOR PROTEIN-LIKE small GTPase#PC00208 HUMAN|HGNC=13757|UniProtKB=Q9HDB9 Q9HDB9 ERVK-5 PTHR40389:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED HUMAN|HGNC=15525|UniProtKB=Q6XYB7 Q6XYB7 LBX2 PTHR24336:SF10 TRANSCRIPTION FACTOR LBX TRANSCRIPTION FACTOR LBX2 homeodomain transcription factor#PC00119 HUMAN|HGNC=31713|UniProtKB=Q5QGZ9 Q5QGZ9 CLEC12A PTHR46490:SF4 C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A HUMAN|HGNC=2014|UniProtKB=Q05315 Q05315 CLC PTHR11346:SF120 GALECTIN GALACTOSIDE-BINDING SOLUBLE LECTIN 13-RELATED extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=3374|UniProtKB=Q99814 Q99814 EPAS1 PTHR23043:SF8 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;response to hypoxia#GO:0001666;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;response to oxygen levels#GO:0070482;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;response to decreased oxygen levels#GO:0036293;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular response to hypoxia#GO:0071456;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;cellular response to stress#GO:0033554;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=8909|UniProtKB=A6NDG6 A6NDG6 PGP PTHR19288:SF82 4-NITROPHENYLPHOSPHATASE-RELATED GLYCEROL-3-PHOSPHATE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181 HUMAN|HGNC=6329|UniProtKB=P43626 P43626 KIR2DL1 PTHR11738:SF113 MHC CLASS I NK CELL RECEPTOR KIR2DL PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=2160|UniProtKB=P34972 P34972 CNR2 PTHR22750:SF10 G-PROTEIN COUPLED RECEPTOR CANNABINOID RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|Ensembl=ENSG00000286075|UniProtKB=A0A0C4DGP1 A0A0C4DGP1 ENSG00000286075 PTHR34446:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 10 FAMILY WITH SEQUENCE SIMILARITY 220 MEMBER A HUMAN|HGNC=2958|UniProtKB=Q92874 Q92874 DNASE1L2 PTHR11371:SF29 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1-LIKE 2 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;endodeoxyribonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;deoxyribonuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;DNA catabolic process, endonucleolytic#GO:0000737;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25252|UniProtKB=Q8IYS0 Q8IYS0 GRAMD1C PTHR23319:SF1 UNCHARACTERIZED PROTEIN ASTER-C HUMAN|HGNC=15248|UniProtKB=Q8NH76 Q8NH76 OR56B4 PTHR26450:SF142 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56B4 transmembrane signal receptor#PC00197 HUMAN|HGNC=25169|UniProtKB=Q96D09 Q96D09 GPRASP2 PTHR46414:SF1 PROTEIN BHLHB9-RELATED G-PROTEIN COUPLED RECEPTOR-ASSOCIATED SORTING PROTEIN 2 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=23435|UniProtKB=Q8N4J0 Q8N4J0 CARNMT1 PTHR12303:SF6 UNCHARACTERIZED CARNOSINE N-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 HUMAN|HGNC=5424|UniProtKB=P01568 P01568 IFNA21 PTHR11691:SF57 TYPE I INTERFERON INTERFERON ALPHA-21 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=17372|UniProtKB=Q9NZ32 Q9NZ32 ACTR10 PTHR11937:SF14 ACTIN ACTIN-RELATED PROTEIN 10 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;protein-DNA complex subunit organization#GO:0071824;histone exchange#GO:0043486;nucleosome organization#GO:0034728;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;ATP-dependent chromatin remodeling#GO:0043044;movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;chromatin organization#GO:0006325;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 actin and actin related protein#PC00039 HUMAN|HGNC=3214|UniProtKB=P13639 P13639 EEF2 PTHR42908:SF10 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR 2 GTPase activity#GO:0003924;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;translation regulator activity#GO:0045182;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 translation elongation factor#PC00222 HUMAN|Ensembl=ENSG00000283071|UniProtKB=A0A0U1RRK4 A0A0U1RRK4 LBHD2 PTHR14987:SF3 PROTEIN LBH-RELATED LBH DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=24281|UniProtKB=Q8N6M0 Q8N6M0 OTUD6B PTHR12419:SF21 OTU DOMAIN CONTAINING PROTEIN DEUBIQUITINASE OTUD6B hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081 HUMAN|HGNC=28334|UniProtKB=Q96BW1 Q96BW1 UPRT PTHR10285:SF171 URIDINE KINASE URACIL PHOSPHORIBOSYLTRANSFERASE HOMOLOG transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uracil phosphoribosyl transferase#P03151 HUMAN|HGNC=13644|UniProtKB=Q9P2F9 Q9P2F9 ZNF319 PTHR24376:SF95 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 319 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7642|UniProtKB=Q99747 Q99747 NAPG PTHR13768:SF2 SOLUBLE NSF ATTACHMENT PROTEIN SNAP GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN membrane traffic protein#PC00150 HUMAN|HGNC=29957|UniProtKB=Q96A70 Q96A70 AZIN2 PTHR11482:SF4 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ANTIZYME INHIBITOR 2 lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;ornithine decarboxylase activity#GO:0004586;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 HUMAN|HGNC=3697|UniProtKB=P09769 P09769 FGR PTHR24418:SF224 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FGR protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell population proliferation#GO:0008283;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;innate immune response#GO:0045087;integrin-mediated signaling pathway#GO:0007229;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;peptidyl-tyrosine modification#GO:0018212;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 Parkinson disease#P00049>Src kinase#P01230 HUMAN|HGNC=1307|UniProtKB=Q9Y3M2 Q9Y3M2 CBY1 PTHR21533:SF20 LEUCINE-RICH PROTEIN PROTEIN CHIBBY HOMOLOG 1 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;Wnt signaling pathway#GO:0016055 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=20149|UniProtKB=Q8N8N7 Q8N8N7 PTGR2 PTHR43205:SF5 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 2 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid derivative metabolic process#GO:1901568;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 reductase#PC00198 HUMAN|HGNC=11135|UniProtKB=Q13487 Q13487 SNAPC2 PTHR15132:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 2 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 2 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29169|UniProtKB=Q9Y2L5 Q9Y2L5 TRAPPC8 PTHR12975:SF6 TRANSPORT PROTEIN TRAPP TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;establishment of protein localization#GO:0045184;protein processing#GO:0016485;amide transport#GO:0042886;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;vacuolar protein processing#GO:0006624;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;peptide transport#GO:0015833;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;intracellular transport#GO:0046907;peroxisome organization#GO:0007031;autophagy#GO:0006914 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;TRAPP complex#GO:0030008;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=34521|UniProtKB=Q6ZU45 Q6ZU45 CLEC20A PTHR45784:SF5 C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 20 MEMBER A-RELATED HUMAN|HGNC=1864|UniProtKB=O00748 O00748 CES2 PTHR11559:SF416 CARBOXYLESTERASE COCAINE ESTERASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 esterase#PC00097 HUMAN|HGNC=23815|UniProtKB=Q6ZU67 Q6ZU67 BEND4 PTHR35082:SF1 BEN DOMAIN-CONTAINING PROTEIN 4 BEN DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=21042|UniProtKB=Q96E22 Q96E22 NUS1 PTHR21528:SF3 UNCHARACTERIZED DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;alcohol biosynthetic process#GO:0046165;protein modification process#GO:0036211;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=3185|UniProtKB=Q15075 Q15075 EEA1 PTHR23164:SF17 EARLY ENDOSOME ANTIGEN 1 EARLY ENDOSOME ANTIGEN 1 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=28105|UniProtKB=Q96PB8 Q96PB8 LRRC3B PTHR24373:SF276 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 3B extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=5740|UniProtKB=P01597 P01597 IGKV1-39 PTHR23267:SF394 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-39-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=16324|UniProtKB=O14990 O14990 PPP1R2C PTHR12398:SF29 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE INHIBITOR 2 FAMILY MEMBER C hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096;protein phosphatase inhibitor activity#GO:0004864 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;regulation of phosphoprotein phosphatase activity#GO:0043666;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of phosphatase activity#GO:0010921;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 phosphatase inhibitor#PC00183 HUMAN|HGNC=6889|UniProtKB=Q8IW41 Q8IW41 MAPKAPK5 PTHR24349:SF179 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 5 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;kinase binding#GO:0019900;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;Ras protein signal transduction#GO:0007265;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=12180|UniProtKB=A0A0K0K1C0 A0A0K0K1C0 TRBV11-1 PTHR23268:SF112 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 11-1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=20657|UniProtKB=O60635 O60635 TSPAN1 PTHR19282:SF216 TETRASPANIN TETRASPANIN-1 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=18191|UniProtKB=Q9C0I1 Q9C0I1 MTMR12 PTHR10807:SF37 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 12 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=21246|UniProtKB=Q8N8W4 Q8N8W4 PNPLA1 PTHR12406:SF23 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;chemical homeostasis#GO:0048878;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 phospholipase#PC00186 HUMAN|HGNC=23096|UniProtKB=Q9BZD2 Q9BZD2 SLC29A3 PTHR10332:SF17 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 3 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;integral component of membrane#GO:0016021;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=41948|UniProtKB=A6NDL7 A6NDL7 METTL21EP PTHR14614:SF1 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN METHYLTRANSFERASE-LIKE PROTEIN 21E PSEUDOGENE-RELATED N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;nitrogen compound metabolic process#GO:0006807;peptidyl-lysine trimethylation#GO:0018023;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=14418|UniProtKB=Q9BW60 Q9BW60 ELOVL1 PTHR11157:SF19 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=2632|UniProtKB=P24903 P24903 CYP2F1 PTHR24300:SF275 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2F1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 cellular aromatic compound metabolic process#GO:0006725;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;organic cyclic compound metabolic process#GO:1901360;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 oxygenase#PC00177 HUMAN|HGNC=21045|UniProtKB=Q9UKF7 Q9UKF7 PITPNC1 PTHR10658:SF55 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CYTOPLASMIC PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 1 cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transporter#PC00227 HUMAN|HGNC=24307|UniProtKB=A4FU01 A4FU01 MTMR11 PTHR10807:SF51 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 11 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=12488|UniProtKB=P68036 P68036 UBE2L3 PTHR24068:SF67 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 L3 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein K11-linked ubiquitination#GO:0070979;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>UbcH7#P01224;Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=17792|UniProtKB=Q96AJ9 Q96AJ9 VTI1A PTHR21230:SF62 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;organelle fusion#GO:0048284;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;protein localization#GO:0008104;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;Golgi to vacuole transport#GO:0006896;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 SNARE protein#PC00034 Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042 HUMAN|HGNC=1636|UniProtKB=P29017 P29017 CD1C PTHR16675:SF155 MHC CLASS I-RELATED T-CELL SURFACE GLYCOPROTEIN CD1C lipid binding#GO:0008289;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 immune response#GO:0006955;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;T cell mediated immunity#GO:0002456;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=9125|UniProtKB=Q13670 Q13670 PMS2P11 PTHR10073:SF52 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MISMATCH REPAIR ENDONUCLEASE PMS2-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=7458|UniProtKB=P03897 P03897 MT-ND3 PTHR11058:SF9 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;membrane#GO:0016020;NADH dehydrogenase complex#GO:0030964;catalytic complex#GO:1902494 oxidoreductase#PC00176 HUMAN|HGNC=1187|UniProtKB=Q9UKR5 Q9UKR5 ERG28 PTHR15451:SF19 ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=16764|UniProtKB=Q15916 Q15916 ZBTB6 PTHR24399:SF36 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=232|UniProtKB=Q08828 Q08828 ADCY1 PTHR45627:SF26 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 1 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of adenylate cyclase activity#GO:0045761;cyclic nucleotide metabolic process#GO:0009187;purine nucleotide biosynthetic process#GO:0006164;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;regulation of response to stimulus#GO:0048583;ribonucleotide biosynthetic process#GO:0009260;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cAMP-mediated signaling#GO:0019933;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;second-messenger-mediated signaling#GO:0019932;organophosphate biosynthetic process#GO:0090407;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;signaling#GO:0023052;metabolic process#GO:0008152;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;response to stimulus#GO:0050896;biological regulation#GO:0065007;nucleobase-containing small molecule metabolic process#GO:0055086;cyclic-nucleotide-mediated signaling#GO:0019935;purine ribonucleotide biosynthetic process#GO:0009152 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 CCKR signaling map#P06959>Adenylate cyclase#P07127;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Gonadotropin-releasing hormone receptor pathway#P06664>AC#P06699;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 HUMAN|HGNC=48329|UniProtKB=K7EJ46 K7EJ46 SMIM22 PTHR36982:SF3 FAMILY NOT NAMED SMALL INTEGRAL MEMBRANE PROTEIN 22 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of cell population proliferation#GO:0042127;cell population proliferation#GO:0008283;regulation of cellular process#GO:0050794 HUMAN|HGNC=30043|UniProtKB=Q9NWQ8 Q9NWQ8 PAG1 PTHR16322:SF0 PHOSPHOPROTEIN ASSOCIATED WITH GLYCOSPHINGOLIPID-ENRICHED MICRODOMAINS 1 PHOSPHOPROTEIN ASSOCIATED WITH GLYCOSPHINGOLIPID-ENRICHED MICRODOMAINS 1 HUMAN|HGNC=5594|UniProtKB=P0DP03 P0DP03 IGHV3-30-5 PTHR23266:SF241 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=12241|UniProtKB=A0A0K0K1E9 A0A0K0K1E9 TRBV7-7 PTHR23268:SF78 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 7-4-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=443|UniProtKB=Q96Q42 Q96Q42 ALS2 PTHR46089:SF3 ALSIN HOMOLOG ALSIN HUMAN|HGNC=30262|UniProtKB=Q96C36 Q96C36 PYCR2 PTHR11645:SF61 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 reductase#PC00198 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 HUMAN|HGNC=18751|UniProtKB=Q8TB24 Q8TB24 RIN3 PTHR23101:SF58 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR 3 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=1696|UniProtKB=P21854 P21854 CD72 PTHR15028:SF6 CD72-RELATED B-CELL DIFFERENTIATION ANTIGEN CD72 HUMAN|HGNC=23683|UniProtKB=Q92928 Q92928 RAB1C PTHR24073:SF1105 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1C-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;vacuole organization#GO:0007033;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;autophagosome assembly#GO:0000045;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;autophagosome organization#GO:1905037;intracellular transport#GO:0046907;autophagy#GO:0006914 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=6796|UniProtKB=P43355 P43355 MAGEA1 PTHR11736:SF49 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18085|UniProtKB=Q8N511 Q8N511 TMEM199 PTHR31394:SF1 TRANSMEMBRANE PROTEIN 199 TRANSMEMBRANE PROTEIN 199 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=24264|UniProtKB=Q9BSY9 Q9BSY9 DESI2 PTHR12378:SF6 DESUMOYLATING ISOPEPTIDASE DEUBIQUITINASE DESI2 hydrolase activity#GO:0016787;ubiquitinyl hydrolase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081 HUMAN|HGNC=12881|UniProtKB=Q8IZC7 Q8IZC7 ZNF101 PTHR24379:SF70 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 101 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9989|UniProtKB=Q15493 Q15493 RGN PTHR10907:SF54 REGUCALCIN REGUCALCIN cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;small molecule biosynthetic process#GO:0044283;carbohydrate metabolic process#GO:0005975;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 esterase#PC00097 HUMAN|HGNC=20418|UniProtKB=Q9NTI5 Q9NTI5 PDS5B PTHR12663:SF1 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED SISTER CHROMATID COHESION PROTEIN PDS5 HOMOLOG B DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;sister chromatid cohesion#GO:0007062;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;nuclear chromosome segregation#GO:0098813;mitotic sister chromatid cohesion#GO:0007064;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;organelle fission#GO:0048285;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=9407|UniProtKB=Q15139 Q15139 PRKD1 PTHR22968:SF9 PROTEIN KINASE C, MU SERINE/THREONINE-PROTEIN KINASE D1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>PKC#P01425;CCKR signaling map#P06959>PRKD1#P07103;Angiogenesis#P00005>PKC#P00219;EGF receptor signaling pathway#P00018>PKC#P00565 HUMAN|HGNC=1095|UniProtKB=P17213 P17213 BPI PTHR10504:SF84 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED BACTERICIDAL PERMEABILITY-INCREASING PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=13394|UniProtKB=Q9NP85 Q9NP85 NPHS2 PTHR10264:SF118 BAND 7 PROTEIN-RELATED PODOCIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=11542|UniProtKB=Q16594 Q16594 TAF9 PTHR48068:SF3 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 9 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;RNA polymerase II general transcription initiation factor activity#GO:0016251 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;histone H3 acetylation#GO:0043966;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear lumen#GO:0031981 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=19987|UniProtKB=Q5JZY3 Q5JZY3 EPHA10 PTHR24416:SF258 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 10 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=25518|UniProtKB=Q9BW85 Q9BW85 YJU2 PTHR12111:SF1 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Lsm2-8 complex#GO:0120115;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=20320|UniProtKB=Q8WXF1 Q8WXF1 PSPC1 PTHR23189:SF14 RNA RECOGNITION MOTIF-CONTAINING PARASPECKLE COMPONENT 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;RNA splicing, via transesterification reactions#GO:0000375;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=12855|UniProtKB=P63104 P63104 YWHAZ PTHR18860:SF7 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA/DELTA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;PI3 kinase pathway#P00048>14-3-3#P01206 HUMAN|HGNC=24235|UniProtKB=Q8TD46 Q8TD46 CD200R1 PTHR21462:SF2 CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 1 transmembrane signal receptor#PC00197 HUMAN|HGNC=28389|UniProtKB=Q6ICG8 Q6ICG8 WBP2NL PTHR31606:SF2 WW DOMAIN BINDING PROTEIN 2, ISOFORM E POSTACROSOMAL SHEATH WW DOMAIN-BINDING PROTEIN nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;transcription coactivator activity#GO:0003713;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=6890|UniProtKB=Q15691 Q15691 MAPRE1 PTHR10623:SF20 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;microtubule polymerization or depolymerization#GO:0031109;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule cytoskeleton organization#GO:0070507;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;protein localization to organelle#GO:0033365;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;protein localization#GO:0008104;organelle assembly#GO:0070925;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=16064|UniProtKB=Q9UJY4 Q9UJY4 GGA2 PTHR45905:SF2 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA2 HUMAN|HGNC=28691|UniProtKB=P60002 P60002 ELOF1 PTHR20934:SF0 UNCHARACTERIZED TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;transcription elongation from RNA polymerase II promoter#GO:0006368;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023 HUMAN|HGNC=3289|UniProtKB=Q13542 Q13542 EIF4EBP2 PTHR12669:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 2 protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;regulation of translational initiation#GO:0006446;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;translational initiation#GO:0006413;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=9836|UniProtKB=Q8NFJ5 Q8NFJ5 GPRC5A PTHR14511:SF7 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 RETINOIC ACID-INDUCED PROTEIN 3 protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;protein kinase activity#GO:0004672;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 receptor complex#GO:0043235;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=26585|UniProtKB=Q14D33 Q14D33 RTP5 PTHR14402:SF2 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 5 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;system process#GO:0003008;nitrogen compound transport#GO:0071705;detection of chemical stimulus#GO:0009593;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein insertion into membrane#GO:0051205;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;detection of stimulus#GO:0051606;nervous system process#GO:0050877;cellular component organization#GO:0016043;sensory perception of chemical stimulus#GO:0007606;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;sensory perception#GO:0007600 HUMAN|HGNC=6129|UniProtKB=P78413 P78413 IRX4 PTHR11211:SF16 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=3723|UniProtKB=Q9Y680 Q9Y680 FKBP7 PTHR46222:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7 chaperone#PC00072 HUMAN|HGNC=20721|UniProtKB=O75132 O75132 ZBED4 PTHR46481:SF1 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=38709|UniProtKB=A8MT65 A8MT65 ZNF891 PTHR24381:SF76 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 891 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=2874|UniProtKB=P15559 P15559 NQO1 PTHR10204:SF1 NAD P H OXIDOREDUCTASE-RELATED NAD(P)H DEHYDROGENASE [QUINONE] 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidoreductase#PC00176 HUMAN|HGNC=10668|UniProtKB=Q86UR1 Q86UR1 NOXA1 PTHR15175:SF4 NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2 NADPH OXIDASE ACTIVATOR 1 Ras GTPase binding#GO:0017016;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;Rac GTPase binding#GO:0048365;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;oxidoreductase activity#GO:0016491;enzyme regulator activity#GO:0030234 cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein-binding activity modulator#PC00095 HUMAN|HGNC=6480|UniProtKB=P00709 P00709 LALBA PTHR11407:SF32 LYSOZYME C ALPHA-LACTALBUMIN HUMAN|HGNC=25018|UniProtKB=Q9P0N5 Q9P0N5 TMEM216 PTHR13531:SF5 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 216 vesicle targeting, to, from or within Golgi#GO:0048199;non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 HUMAN|HGNC=26802|UniProtKB=Q8TBE1 Q8TBE1 CNIH3 PTHR12290:SF12 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 3 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;signal transduction#GO:0007165;regulation of neurotransmitter receptor activity#GO:0099601;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;ionotropic glutamate receptor signaling pathway#GO:0035235;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;regulation of AMPA receptor activity#GO:2000311;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of signaling receptor activity#GO:0010469;response to stimulus#GO:0050896;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 synapse#GO:0045202;somatodendritic compartment#GO:0036477;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;dendrite#GO:0030425;organelle membrane#GO:0031090;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;cell projection#GO:0042995;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=5017|UniProtKB=Q9NP08 Q9NP08 HMX1 PTHR46110:SF1 HOMEOBOX PROTEIN HMX HOMEOBOX PROTEIN HMX1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=3767|UniProtKB=P35916 P35916 FLT4 PTHR24416:SF49 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VEGFR-2#P00222;VEGF signaling pathway#P00056>VEGFR-2#P01403 HUMAN|HGNC=6923|UniProtKB=Q9NR56 Q9NR56 MBNL1 PTHR12675:SF7 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 1 RNA splicing factor#PC00148 HUMAN|HGNC=21023|UniProtKB=Q9GZM5 Q9GZM5 YIPF3 PTHR15627:SF14 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 PROTEIN YIPF3 HUMAN|HGNC=13575|UniProtKB=O60885 O60885 BRD4 PTHR22880:SF143 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=30940|UniProtKB=Q9HCE3 Q9HCE3 ZNF532 PTHR47222:SF3 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 532 HUMAN|HGNC=26139|UniProtKB=Q0VDI3 Q0VDI3 TMEM267 PTHR13628:SF1 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 267 HUMAN|HGNC=7459|UniProtKB=P03905 P03905 MT-ND4 PTHR43507:SF1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4 oxidoreductase activity#GO:0016491;binding#GO:0005488;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;energy derivation by oxidation of organic compounds#GO:0015980;cation transmembrane transport#GO:0098655;localization#GO:0051179;establishment of localization#GO:0051234;oxidation-reduction process#GO:0055114;metabolic process#GO:0008152 respirasome#GO:0070469;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;respiratory chain complex I#GO:0045271;cellular anatomical entity#GO:0110165;membrane#GO:0016020;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=19323|UniProtKB=Q96HU8 Q96HU8 DIRAS2 PTHR24070:SF178 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=17337|UniProtKB=P62502 P62502 LCN6 PTHR11430:SF10 LIPOCALIN EPIDIDYMAL-SPECIFIC LIPOCALIN-6 transfer/carrier protein#PC00219 HUMAN|HGNC=8655|UniProtKB=Q08174 Q08174 PCDH1 PTHR24028:SF247 CADHERIN-87A PROTOCADHERIN-1 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=30825|UniProtKB=Q8NFZ8 Q8NFZ8 CADM4 PTHR45889:SF3 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 4 HUMAN|HGNC=7598|UniProtKB=O94832 O94832 MYO1D PTHR13140:SF417 MYOSIN UNCONVENTIONAL MYOSIN-ID pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 microvillus#GO:0005902;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=5386|UniProtKB=P51553 P51553 IDH3G PTHR11835:SF60 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT GAMMA, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;oxidation-reduction process#GO:0055114;secondary alcohol metabolic process#GO:1902652;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 HUMAN|HGNC=25069|UniProtKB=Q6PJ61 Q6PJ61 FBXO46 PTHR16271:SF10 F-BOX ONLY PROTEIN 34/46 FAMILY MEMBER F-BOX ONLY PROTEIN 46 HUMAN|HGNC=11497|UniProtKB=Q96PV0 Q96PV0 SYNGAP1 PTHR10194:SF25 RAS GTPASE-ACTIVATING PROTEINS RAS/RAP GTPASE-ACTIVATING PROTEIN SYNGAP GTPase-activating protein#PC00257 HUMAN|HGNC=37222|UniProtKB=P86480 P86480 PRR20D PTHR38819:SF1 PROLINE-RICH PROTEIN 20A-RELATED PROLINE-RICH PROTEIN 20A-RELATED HUMAN|HGNC=28963|UniProtKB=Q15006 Q15006 EMC2 PTHR12760:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN ER MEMBRANE PROTEIN COMPLEX SUBUNIT 2 cellular process#GO:0009987;protein folding#GO:0006457 membrane protein complex#GO:0098796;ER membrane protein complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=11820|UniProtKB=P01033 P01033 TIMP1 PTHR11844:SF20 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 1 metalloendopeptidase activity#GO:0004222;peptidase inhibitor activity#GO:0030414;metallopeptidase activity#GO:0008237;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of catabolic process#GO:0009895;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=15864|UniProtKB=Q9BYM8 Q9BYM8 RBCK1 PTHR22770:SF35 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED RANBP-TYPE AND C3HC4-TYPE ZINC FINGER-CONTAINING PROTEIN 1 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin binding#GO:0043130;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;protein catabolic process#GO:0030163;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;intracellular signal transduction#GO:0035556;proteasomal protein catabolic process#GO:0010498;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=31746|UniProtKB=A1L4L8 A1L4L8 PLAC8L1 PTHR15907:SF122 DUF614 FAMILY PROTEIN-RELATED PLAC8-LIKE PROTEIN 1 HUMAN|HGNC=14339|UniProtKB=Q9H4M7 Q9H4M7 PLEKHA4 PTHR12752:SF7 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 4 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell junction organization#GO:0034330;biological adhesion#GO:0022610;protein-containing complex assembly#GO:0065003;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;apical junction complex#GO:0043296 HUMAN|HGNC=14537|UniProtKB=P61916 P61916 NPC2 PTHR11306:SF30 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 2 lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869 HUMAN|HGNC=24063|UniProtKB=Q96C23 Q96C23 GALM PTHR10091:SF0 ALDOSE-1-EPIMERASE GALACTOSE MUTAROTASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;small molecule catabolic process#GO:0044282;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;glucose metabolic process#GO:0006006;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 epimerase/racemase#PC00096 HUMAN|HGNC=13506|UniProtKB=Q8TBJ5 Q8TBJ5 FEZF2 PTHR16515:SF35 PR DOMAIN ZINC FINGER PROTEIN FEZ FAMILY ZINC FINGER PROTEIN 2 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=18935|UniProtKB=Q8IUC2 Q8IUC2 KRTAP8-1 PTHR36131:SF1 KERATIN-ASSOCIATED PROTEIN 8-1 KERATIN-ASSOCIATED PROTEIN 8-1 HUMAN|HGNC=30855|UniProtKB=O15042 O15042 U2SURP PTHR23140:SF0 RNA PROCESSING PROTEIN LD23810P U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN RNA processing factor#PC00147 HUMAN|HGNC=10499|UniProtKB=P06702 P06702 S100A9 PTHR11639:SF79 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A9 localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;multicellular organismal process#GO:0032501;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;endothelial cell migration#GO:0043542;locomotion#GO:0040011 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;extracellular region#GO:0005576;intracellular organelle lumen#GO:0070013;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 calmodulin-related#PC00061 HUMAN|HGNC=11251|UniProtKB=Q08629 Q08629 SPOCK1 PTHR13866:SF17 SPARC OSTEONECTIN TESTICAN-1 cation binding#GO:0043169;extracellular matrix binding#GO:0050840;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=25187|UniProtKB=Q96BW9 Q96BW9 TAMM41 PTHR13619:SF0 UNCHARACTERIZED PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL HUMAN|HGNC=29654|UniProtKB=Q569H4 Q569H4 PRR16 PTHR15917:SF0 FAMILY NOT NAMED PROTEIN LARGEN HUMAN|HGNC=23822|UniProtKB=Q86YR6 Q86YR6 POTED PTHR24118:SF65 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER B-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=14487|UniProtKB=O75394 O75394 MRPL33 PTHR47037:SF1 39S RIBOSOMAL PROTEIN L33, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L33, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ribosomal protein#PC00202 HUMAN|HGNC=6469|UniProtKB=Q16719 Q16719 KYNU PTHR14084:SF0 KYNURENINASE KYNURENINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid family metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular amino acid catabolic process#GO:0009063;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;cellular amino acid metabolic process#GO:0006520;aromatic amino acid family catabolic process#GO:0009074;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 HUMAN|HGNC=11487|UniProtKB=Q15431 Q15431 SYCP1 PTHR46918:SF1 SYNAPTONEMAL COMPLEX PROTEIN 1 SYNAPTONEMAL COMPLEX PROTEIN 1 HUMAN|HGNC=69|UniProtKB=P61221 P61221 ABCE1 PTHR19248:SF16 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY E MEMBER 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;iron ion binding#GO:0005506;nucleoside phosphate binding#GO:1901265;ribonucleoprotein complex binding#GO:0043021;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-containing complex disassembly#GO:0032984;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;protein transport#GO:0015031;intracellular transport#GO:0046907;translational elongation#GO:0006414;protein-containing complex localization#GO:0031503;ribosomal subunit export from nucleus#GO:0000054;cellular protein complex disassembly#GO:0043624;macromolecule localization#GO:0033036;peptide metabolic process#GO:0006518;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nucleic acid transport#GO:0050657;biosynthetic process#GO:0009058;ribonucleoprotein complex export from nucleus#GO:0071426;translation#GO:0006412;amide transport#GO:0042886;organic substance transport#GO:0071702;translational termination#GO:0006415;cellular component disassembly#GO:0022411;cellular nitrogen compound biosynthetic process#GO:0044271;protein export from nucleus#GO:0006611;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;ribonucleoprotein complex localization#GO:0071166;cellular process#GO:0009987;localization#GO:0051179;amide biosynthetic process#GO:0043604;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;translational initiation#GO:0006413;intracellular protein transport#GO:0006886;RNA export from nucleus#GO:0006405;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular#GO:0005622 HUMAN|HGNC=24871|UniProtKB=Q8N6N3 Q8N6N3 C1orf52 PTHR31833:SF2 UPF0690 PROTEIN C1ORF52 UPF0690 PROTEIN C1ORF52 HUMAN|HGNC=34360|UniProtKB=Q6ZNW5 Q6ZNW5 GDPGP1 PTHR20884:SF8 GDP-D-GLUCOSE PHOSPHORYLASE 1 GDP-D-GLUCOSE PHOSPHORYLASE 1 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;glucose metabolic process#GO:0006006;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=21387|UniProtKB=Q8N3Z0 Q8N3Z0 PRSS35 PTHR15462:SF17 SERINE PROTEASE INACTIVE SERINE PROTEASE 35 serine protease#PC00203 HUMAN|HGNC=21648|UniProtKB=Q9P0U1 Q9P0U1 TOMM7 PTHR46722:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG primary active transporter#PC00068 HUMAN|HGNC=11231|UniProtKB=Q8WXF7 Q8WXF7 ATL1 PTHR10751:SF15 GUANYLATE BINDING PROTEIN ATLASTIN-1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 heterotrimeric G-protein#PC00117 HUMAN|HGNC=44204|UniProtKB=B2RUZ4 B2RUZ4 SMIM1 PTHR38503:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 1 SMALL INTEGRAL MEMBRANE PROTEIN 1 HUMAN|HGNC=20255|UniProtKB=Q9UHJ3 Q9UHJ3 SFMBT1 PTHR12247:SF77 POLYCOMB GROUP PROTEIN SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 1 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=9087|UniProtKB=Q04941 Q04941 PLP2 PTHR22776:SF4 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PROTEOLIPID PROTEIN 2 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=20601|UniProtKB=Q6PIS1 Q6PIS1 SLC23A3 PTHR11119:SF57 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 3 transporter#PC00227 HUMAN|HGNC=4856|UniProtKB=P51858 P51858 HDGF PTHR12550:SF41 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=2348|UniProtKB=Q92793 Q92793 CREBBP PTHR13808:SF34 CBP/P300-RELATED CREB-BINDING PROTEIN transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;nucleic acid binding#GO:0003676;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;transcription factor binding#GO:0008134;N-acyltransferase activity#GO:0016410;transcription coregulator activity#GO:0003712;histone acetyltransferase activity#GO:0004402;transcription regulator activity#GO:0140110;chromatin DNA binding#GO:0031490;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;peptide-lysine-N-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II transcription factor binding#GO:0001085;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone acetyltransferase complex#GO:0000123;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Hedgehog signaling pathway#P00025>CBP#P00691;p53 pathway#P00059>CBP#P04623;Wnt signaling pathway#P00057>CBP#P01448;Transcription regulation by bZIP transcription factor#P00055>CBP/P300#P01387;Hypoxia response via HIF activation#P00030>P300#P00814;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Huntington disease#P00029>CBP#P00777;Gonadotropin-releasing hormone receptor pathway#P06664>CBP#P06755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 HUMAN|HGNC=24949|UniProtKB=Q01804 Q01804 OTUD4 PTHR12419:SF9 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 4 thiol-dependent ubiquitin-specific protease activity#GO:0004843;hydrolase activity#GO:0016787;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;pattern recognition receptor signaling pathway#GO:0002221;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;cytokine-mediated signaling pathway#GO:0019221;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;protein modification by small protein conjugation or removal#GO:0070647;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;protein K48-linked deubiquitination#GO:0071108;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;response to interleukin-1#GO:0070555;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cysteine protease#PC00081 HUMAN|HGNC=26141|UniProtKB=Q9H6X5 Q9H6X5 C19orf44 PTHR22409:SF2 UNCHARACTERIZED DUF4614 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=11949|UniProtKB=P45379 P45379 TNNT2 PTHR11521:SF5 TROPONIN T TROPONIN T, CARDIAC MUSCLE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 blood circulation#GO:0008015;cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cardiac muscle contraction#GO:0060048;heart contraction#GO:0060047;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;circulatory system process#GO:0003013;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle contraction#GO:0006941;cellular component morphogenesis#GO:0032989;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 actin binding motor protein#PC00040 HUMAN|HGNC=4446|UniProtKB=O43292 O43292 GPAA1 PTHR13304:SF0 GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=22652|UniProtKB=Q5JPE7 Q5JPE7 NOMO2 PTHR23303:SF14 CARBOXYPEPTIDASE REGULATORY REGION-CONTAINING NODAL MODULATOR 1-RELATED cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=3501|UniProtKB=O60447 O60447 EVI5 PTHR22957:SF497 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN ECOTROPIC VIRAL INTEGRATION SITE 5 PROTEIN HOMOLOG GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=21602|UniProtKB=Q9NU19 Q9NU19 TBC1D22B PTHR22957:SF462 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 22B GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=9143|UniProtKB=Q99453 Q99453 PHOX2B PTHR24329:SF301 HOMEOBOX PROTEIN ARISTALESS PAIRED MESODERM HOMEOBOX PROTEIN 2B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=8773|UniProtKB=Q9HCR9 Q9HCR9 PDE11A PTHR11347:SF130 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL 3',5'-CYCLIC-AMP AND -GMP PHOSPHODIESTERASE 11A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 phosphodiesterase#PC00185 HUMAN|HGNC=28356|UniProtKB=Q8TBP0 Q8TBP0 TBC1D16 PTHR22957:SF626 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 16 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;regulation of GTPase activity#GO:0043087;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 HUMAN|HGNC=9635|UniProtKB=Q12974 Q12974 PTP4A2 PTHR23339:SF65 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 HUMAN|HGNC=19404|UniProtKB=Q8NFA2 Q8NFA2 NOXO1 PTHR15706:SF10 SH3 MULTIPLE DOMAIN NADPH OXIDASE ORGANIZER 1 HUMAN|HGNC=16818|UniProtKB=Q08623 Q08623 PUDP PTHR18901:SF43 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE-5'-PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181 HUMAN|HGNC=16166|UniProtKB=Q96LM9 Q96LM9 C20orf173 PTHR46032:SF7 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 RIKEN CDNA 6430550D23 GENE transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 transferase#PC00220 HUMAN|HGNC=32528|UniProtKB=Q00LT1 Q00LT1 PRCD PTHR38501:SF1 PHOTORECEPTOR DISK COMPONENT PRCD PHOTORECEPTOR DISK COMPONENT PRCD protein binding#GO:0005515;binding#GO:0005488 9+0 non-motile cilium#GO:0097731;bounding membrane of organelle#GO:0098588;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;protein-containing complex#GO:0032991;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=20286|UniProtKB=Q9H3H1 Q9H3H1 TRIT1 PTHR11088:SF25 TRNA DIMETHYLALLYLTRANSFERASE TRNA DIMETHYLALLYLTRANSFERASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA processing factor#PC00147 HUMAN|HGNC=32036|UniProtKB=A8MXV4 A8MXV4 NUDT19 PTHR12318:SF0 TESTOSTERONE-REGULATED PROTEIN RP2 NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 19 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=23146|UniProtKB=Q86WK9 Q86WK9 PAQR7 PTHR20855:SF41 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496 response to organic substance#GO:0010033;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to organic cyclic compound#GO:0014070;response to hormone#GO:0009725;response to chemical#GO:0042221;response to lipid#GO:0033993;response to steroid hormone#GO:0048545 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=18454|UniProtKB=P58294 P58294 PROK1 PTHR18821:SF7 PROKINETICIN PROKINETICIN-1 peptide hormone#PC00179 HUMAN|HGNC=37213|UniProtKB=C9JXX5 C9JXX5 C11orf94 PTHR37872:SF1 SIMILAR TO RIKEN CDNA 1700029I15 SIMILAR TO RIKEN CDNA 1700029I15 HUMAN|HGNC=26128|UniProtKB=Q9H741 Q9H741 SPRING PTHR13481:SF0 UNCHARACTERIZED SREBP REGULATING GENE PROTEIN HUMAN|HGNC=6300|UniProtKB=Q96KK3 Q96KK3 KCNS1 PTHR11537:SF61 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY S MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;monovalent inorganic cation transport#GO:0015672;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;ion transport#GO:0006811;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;regulation of ion transport#GO:0043269 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=27609|UniProtKB=Q5UCC4 Q5UCC4 EMC10 PTHR21397:SF4 CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=7889|UniProtKB=Q9Y5S8 Q9Y5S8 NOX1 PTHR11972:SF71 NADPH OXIDASE NADPH OXIDASE 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;oxidoreductase complex#GO:1990204;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175 HUMAN|HGNC=9477|UniProtKB=P56730 P56730 PRSS12 PTHR48071:SF5 SRCR DOMAIN-CONTAINING PROTEIN NEUROTRYPSIN presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;extracellular region#GO:0005576;cell junction#GO:0030054;terminal bouton#GO:0043195;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;axon terminus#GO:0043679;neuron projection terminus#GO:0044306;neuron projection#GO:0043005;plasma membrane region#GO:0098590;distal axon#GO:0150034;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=16132|UniProtKB=Q9BYN0 Q9BYN0 SRXN1 PTHR21348:SF2 UNCHARACTERIZED SULFIREDOXIN-1 HUMAN|HGNC=26354|UniProtKB=Q96LJ8 Q96LJ8 UBXN10 PTHR23322:SF28 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 10 HUMAN|HGNC=19213|UniProtKB=Q96MC5 Q96MC5 BMERB1 PTHR22704:SF1 UNCHARACTERIZED BMERB DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=31351|UniProtKB=P0C7Q6 P0C7Q6 SLC35G6 PTHR22911:SF110 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G6 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=19055|UniProtKB=Q5RKV6 Q5RKV6 EXOSC6 PTHR11953:SF2 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT MTR3 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;snRNA processing#GO:0016180;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;snRNA metabolic process#GO:0016073;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;exosome (RNase complex)#GO:0000178 exoribonuclease#PC00099 HUMAN|HGNC=13180|UniProtKB=Q9HBF4 Q9HBF4 ZFYVE1 PTHR46624:SF3 AGAP002036-PA ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=2026|UniProtKB=P51800 P51800 CLCNKA PTHR45720:SF16 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN CLC-KA inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;chloride transport#GO:0006821;establishment of localization#GO:0051234;anion transport#GO:0006820;inorganic anion transport#GO:0015698;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=9245|UniProtKB=Q13136 Q13136 PPFIA1 PTHR12587:SF15 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-1 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 HUMAN|HGNC=8528|UniProtKB=P01178 P01178 OXT PTHR11681:SF2 NEUROPHYSIN OXYTOCIN-NEUROPHYSIN 1 neuropeptide hormone activity#GO:0005184;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 neuropeptide#PC00162 Opioid prodynorphin pathway#P05916>provasopressin#P05999;Opioid prodynorphin pathway#P05916>prepropressophysin#G06050;Vasopressin synthesis#P04395>Pro-Vasopressin#P04598;Vasopressin synthesis#P04395>Signal Peptide#P04597;Opioid prodynorphin pathway#P05916>vasopressin#P06000;Vasopressin synthesis#P04395>Vasopressin#P04590;Opioid prodynorphin pathway#P05916>prepropressophysin#G06048;Vasopressin synthesis#P04395>Pro-Neurophysin#P04591;Vasopressin synthesis#P04395>Glycopeptide#P04593;Vasopressin synthesis#P04395>Pro2-Vasopressin#P04595;Vasopressin synthesis#P04395>Neurophysin#P04594 HUMAN|HGNC=3309|UniProtKB=P08246 P08246 ELANE PTHR24257:SF16 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER NEUTROPHIL ELASTASE serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 immune response#GO:0006955;macromolecule metabolic process#GO:0043170;phagocytosis#GO:0006909;transport#GO:0006810;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;inflammatory response#GO:0006954;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;defense response#GO:0006952;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=25609|UniProtKB=Q32MH5 Q32MH5 FAM214A PTHR13199:SF13 GH03947P PROTEIN FAM214A HUMAN|HGNC=24679|UniProtKB=Q96IG2 Q96IG2 FBXL20 PTHR13318:SF47 UNCHARACTERIZED F-BOX/LRR-REPEAT PROTEIN 20 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=13934|UniProtKB=A0A0B4J1T7 A0A0B4J1T7 LY6G6E PTHR14569:SF0 LYMPHOCYTE ANTIGEN 6 FAMILY MEMBER G6E ACTIVIN_RECP DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;cation binding#GO:0043169;postsynaptic neurotransmitter receptor activity#GO:0098960;acetylcholine receptor activity#GO:0015464;molecular function regulator#GO:0098772;protein binding#GO:0005515;molecular transducer activity#GO:0060089;acetylcholine receptor regulator activity#GO:0030548;ion binding#GO:0043167;acetylcholine binding#GO:0042166 response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of G protein-coupled receptor signaling pathway#GO:0008277;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=12969|UniProtKB=P17022 P17022 ZNF18 PTHR23226:SF190 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 18 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1346|UniProtKB=P10643 P10643 C7 PTHR45742:SF2 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C7 HUMAN|HGNC=31255|UniProtKB=Q8NG76 Q8NG76 OR2T33 PTHR26453:SF286 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T33-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=29612|UniProtKB=Q13571 Q13571 LAPTM5 PTHR12479:SF2 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 5 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 HUMAN|HGNC=10565|UniProtKB=O14828 O14828 SCAMP3 PTHR10687:SF6 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 3 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 HUMAN|HGNC=1104|UniProtKB=Q15059 Q15059 BRD3 PTHR22880:SF20 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=857|UniProtKB=P36543 P36543 ATP6V1E1 PTHR45715:SF2 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED V-TYPE PROTON ATPASE SUBUNIT E 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 HUMAN|HGNC=7892|UniProtKB=P00491 P00491 PNP PTHR11904:SF12 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotide kinase#PC00172 Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Purine metabolism#P02769>Nucleoside Phosphorylase#P03115;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812 HUMAN|HGNC=8780|UniProtKB=P27815 P27815 PDE4A PTHR11347:SF74 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 HUMAN|HGNC=164|UniProtKB=P35609 P35609 ACTN2 PTHR11915:SF429 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-2 Integrin signalling pathway#P00034>alpha actinin#P00928 HUMAN|HGNC=35165|UniProtKB=P0DMQ5 P0DMQ5 INAFM2 PTHR34929:SF4 ZGC:153157 TRANSMEMBRANE PROTEIN INAFM2-RELATED calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;channel activity#GO:0015267;transporter activity#GO:0005215 HUMAN|HGNC=6553|UniProtKB=P41159 P41159 LEP PTHR11724:SF1 LEPTIN LEPTIN peptide hormone#PC00179 HUMAN|HGNC=21416|UniProtKB=Q92485 Q92485 SMPDL3B PTHR10340:SF25 SPHINGOMYELIN PHOSPHODIESTERASE ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3B phosphodiesterase#PC00185 HUMAN|HGNC=28148|UniProtKB=Q96LW7 Q96LW7 CARD19 PTHR34765:SF1 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 19 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 19 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11204|UniProtKB=P48436 P48436 SOX9 PTHR45803:SF1 SOX100B TRANSCRIPTION FACTOR SOX-9 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;gliogenesis#GO:0042063;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;oligodendrocyte differentiation#GO:0048709;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;neurogenesis#GO:0022008;heart development#GO:0007507;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;glial cell differentiation#GO:0010001;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;connective tissue development#GO:0061448;chondrocyte differentiation#GO:0002062;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;positive regulation of developmental process#GO:0051094;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;cartilage development#GO:0051216;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28561|UniProtKB=Q8IXW0 Q8IXW0 LMNTD2 PTHR19956:SF5 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=11712|UniProtKB=Q9BXT4 Q9BXT4 TDRD1 PTHR22948:SF4 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=45241|UniProtKB=Q2QD12 Q2QD12 RPEL1 PTHR11749:SF3 RIBULOSE-5-PHOSPHATE-3-EPIMERASE RIBULOSE-PHOSPHATE 3-EPIMERASE-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;isomerase activity#GO:0016853;ion binding#GO:0043167;binding#GO:0005488;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;glucose 6-phosphate metabolic process#GO:0051156;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;oxidation-reduction process#GO:0055114;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852 HUMAN|HGNC=9007|UniProtKB=Q96J94 Q96J94 PIWIL1 PTHR22891:SF46 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 1 translation initiation factor#PC00224 HUMAN|HGNC=3513|UniProtKB=Q93063 Q93063 EXT2 PTHR11062:SF338 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-2-RELATED glycosyltransferase#PC00111 HUMAN|HGNC=32225|UniProtKB=Q9Y4P8 Q9Y4P8 WIPI2 PTHR11227:SF27 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy of nucleus#GO:0044804;autophagy#GO:0006914 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;whole membrane#GO:0098805 HUMAN|HGNC=37258|UniProtKB=C9J202 C9J202 ALG1L2 PTHR13036:SF2 BETA1,4 MANNOSYLTRANSFERASE GLYCOSYLTRANSFERASE ALG1L2-RELATED transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=23115|UniProtKB=Q96CJ1 Q96CJ1 EAF2 PTHR15970:SF7 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR 2 HUMAN|HGNC=4792|UniProtKB=Q99525 Q99525 H4C7 PTHR10484:SF180 HISTONE H4 HISTONE H4-LIKE PROTEIN TYPE G protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=22043|UniProtKB=Q8N859 Q8N859 ZNF713 PTHR24384:SF80 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 713 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=10307|UniProtKB=P18621 P18621 RPL17 PTHR11593:SF11 60S RIBOSOMAL PROTEIN L17 60S RIBOSOMAL PROTEIN L17 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=19364|UniProtKB=Q8IZC4 Q8IZC4 RTKN2 PTHR21538:SF21 ANILLIN/RHOTEKIN RTKN RHOTEKIN-2 Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;GTP-Rho binding#GO:0017049;Rho GTPase binding#GO:0017048 cellular component biogenesis#GO:0044085;cell division#GO:0051301;assembly of actomyosin apparatus involved in cytokinesis#GO:0000912;membrane organization#GO:0061024;actomyosin contractile ring assembly#GO:0000915;nuclear division#GO:0000280;animal organ development#GO:0048513;developmental process#GO:0032502;cell cycle process#GO:0022402;hematopoietic or lymphoid organ development#GO:0048534;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;cytokinetic process#GO:0032506;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cytokinesis#GO:0000281;system development#GO:0048731;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;cytoskeleton-dependent cytokinesis#GO:0061640;hemopoiesis#GO:0030097;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;positive regulation of biological process#GO:0048518;cytokinesis#GO:0000910;cellular component assembly#GO:0022607;actomyosin contractile ring organization#GO:0044837;membrane fission#GO:0090148;regulation of cell population proliferation#GO:0042127;septin ring organization#GO:0031106;immune system development#GO:0002520;multicellular organism development#GO:0007275;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;immune system process#GO:0002376;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;organelle fission#GO:0048285;actin cytoskeleton organization#GO:0030036;cortical actin cytoskeleton organization#GO:0030866;septin cytoskeleton organization#GO:0032185 cortical cytoskeleton#GO:0030863;actomyosin contractile ring#GO:0005826;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;contractile ring#GO:0070938;cell division site#GO:0032153;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 HUMAN|HGNC=17196|UniProtKB=Q8NG08 Q8NG08 HELB PTHR18934:SF135 ATP-DEPENDENT RNA HELICASE DNA HELICASE B nucleic acid binding#GO:0003676;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;DNA-dependent ATPase activity#GO:0008094;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;single-stranded DNA helicase activity#GO:0017116;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;negative regulation of gene expression#GO:0010629;negative regulation of response to DNA damage stimulus#GO:2001021;regulation of double-strand break repair#GO:2000779;regulation of response to DNA damage stimulus#GO:2001020;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;negative regulation of DNA metabolic process#GO:0051053;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of double-strand break repair via homologous recombination#GO:2000042;nucleobase-containing compound catabolic process#GO:0034655;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;RNA metabolic process#GO:0016070;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;negative regulation of DNA repair#GO:0045738;regulation of DNA repair#GO:0006282;regulation of double-strand break repair via homologous recombination#GO:0010569;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;negative regulation of DNA recombination#GO:0045910;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of double-strand break repair#GO:2000780;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;regulation of DNA recombination#GO:0000018;cellular macromolecule catabolic process#GO:0044265;DNA metabolic process#GO:0006259 RNA helicase#PC00032 HUMAN|HGNC=4206|UniProtKB=P04001 P04001 OPN1MW PTHR24240:SF17 OPSIN MEDIUM-WAVE-SENSITIVE OPSIN 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to abiotic stimulus#GO:0071214;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=23633|UniProtKB=Q9HBL7 Q9HBL7 PLGRKT PTHR13411:SF6 PLASMINOGEN RECEPTOR (KT) PLASMINOGEN RECEPTOR (KT) positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;positive regulation of proteolysis#GO:0045862;protein processing#GO:0016485;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;zymogen activation#GO:0031638;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=11289|UniProtKB=P36956 P36956 SREBF1 PTHR46062:SF2 STEROL REGULATORY ELEMENT-BINDING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16288|UniProtKB=Q9C026 Q9C026 TRIM9 PTHR24099:SF13 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM9 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=17134|UniProtKB=Q9BRT8 Q9BRT8 CBWD1 PTHR13748:SF31 COBW-RELATED COBW DOMAIN-CONTAINING PROTEIN 1-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=1336|UniProtKB=Q9NYF3 Q9NYF3 FAM53C PTHR28567:SF4 FAMILY NOT NAMED PROTEIN FAM53C cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=21484|UniProtKB=Q9NXL9 Q9NXL9 MCM9 PTHR11630:SF48 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA HELICASE MCM9 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=20376|UniProtKB=Q8NBK3 Q8NBK3 SUMF1 PTHR23150:SF19 SULFATASE MODIFYING FACTOR 1, 2 FORMYLGLYCINE-GENERATING ENZYME HUMAN|HGNC=18344|UniProtKB=Q9BX68 Q9BX68 HINT2 PTHR23089:SF18 HISTIDINE TRIAD HIT PROTEIN HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotide phosphatase#PC00173 HUMAN|HGNC=9155|UniProtKB=P16233 P16233 PNLIP PTHR11610:SF147 LIPASE PANCREATIC TRIACYLGLYCEROL LIPASE hydrolase activity#GO:0016787;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;lipid catabolic process#GO:0016042;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 lipase#PC00143 HUMAN|HGNC=33426|UniProtKB=B5MD39 B5MD39 GGTLC3 PTHR45027:SF6 PUTATIVE GLUTATHIONE HYDROLASE LIGHT CHAIN GLUTATHIONE HYDROLASE LIGHT CHAIN 3-RELATED hydrolase#PC00121 HUMAN|HGNC=18137|UniProtKB=Q7LFX5 Q7LFX5 CHST15 PTHR15723:SF0 CARBOHYDRATE SULFOTRANSFERASE 15 CARBOHYDRATE SULFOTRANSFERASE 15 transferase#PC00220 HUMAN|HGNC=24665|UniProtKB=Q6Q8B3 Q6Q8B3 CD200R1L PTHR21462:SF3 CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 external side of plasma membrane#GO:0009897;leaflet of membrane bilayer#GO:0097478;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=6322|UniProtKB=Q2VIQ3 Q2VIQ3 KIF4B PTHR47969:SF17 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED CHROMOSOME-ASSOCIATED KINESIN KIF4B mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 microtubule binding motor protein#PC00156 HUMAN|HGNC=33877|UniProtKB=B1AL88 B1AL88 FAM155A PTHR15819:SF9 TRANSMEMBRANE PROTEIN FAM155 TRANSMEMBRANE PROTEIN FAM155A calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;divalent metal ion transport#GO:0070838;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=3402|UniProtKB=P34913 P34913 EPHX2 PTHR43329:SF1 EPOXIDE HYDROLASE BIFUNCTIONAL EPOXIDE HYDROLASE 2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=30785|UniProtKB=Q9UHR5 Q9UHR5 SAP30BP PTHR13464:SF0 TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP SAP30-BINDING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=30949|UniProtKB=Q96MM3 Q96MM3 ZFP42 PTHR14003:SF8 TRANSCRIPTIONAL REPRESSOR PROTEIN YY ZINC FINGER PROTEIN 42 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=14887|UniProtKB=O75953 O75953 DNAJB5 PTHR24078:SF525 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 5 protein binding#GO:0005515;unfolded protein binding#GO:0051082;chaperone binding#GO:0051087;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;chaperone-mediated protein folding#GO:0061077;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;protein folding#GO:0006457;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;'de novo' protein folding#GO:0006458;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=27145|UniProtKB=C9JJ37 C9JJ37 BTBD19 PTHR46965:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 19 BTB/POZ DOMAIN-CONTAINING PROTEIN 19 HUMAN|HGNC=12442|UniProtKB=P14679 P14679 TYR PTHR11474:SF76 TYROSINASE FAMILY MEMBER TYROSINASE oxygenase#PC00177 HUMAN|HGNC=13032|UniProtKB=P17028 P17028 ZNF24 PTHR23226:SF127 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 24 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15592|UniProtKB=O75177 O75177 SS18L1 PTHR23107:SF21 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN CALCIUM-RESPONSIVE TRANSACTIVATOR-RELATED positive regulation of gene expression#GO:0010628;regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;dendrite development#GO:0016358;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;aromatic compound biosynthetic process#GO:0019438;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of dendrite morphogenesis#GO:0048814;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;positive regulation of cell projection organization#GO:0031346;positive regulation of RNA biosynthetic process#GO:1902680;regulation of anatomical structure morphogenesis#GO:0022603;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;positive regulation of neuron differentiation#GO:0045666;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;dendrite morphogenesis#GO:0048813;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=6179|UniProtKB=P27987 P27987 ITPKB PTHR12400:SF4 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE B transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 HUMAN|HGNC=20265|UniProtKB=Q9NXR5 Q9NXR5 ANKRD10 PTHR24203:SF14 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 10 HUMAN|HGNC=16758|UniProtKB=Q9UBW8 Q9UBW8 COPS7A PTHR15350:SF7 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 SIGNALOSOME COMPLEX SUBUNIT 7A protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229 HUMAN|HGNC=22301|UniProtKB=Q7Z7H5 Q7Z7H5 TMED4 PTHR22811:SF38 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 4 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;Golgi organization#GO:0007030;macromolecule metabolic process#GO:0043170;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;aromatic compound biosynthetic process#GO:0019438;intracellular transport#GO:0046907;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;transport#GO:0006810;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;amide transport#GO:0042886;positive regulation of response to stimulus#GO:0048584;organic substance transport#GO:0071702;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;Golgi vesicle transport#GO:0048193;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=6284|UniProtKB=Q12791 Q12791 KCNMA1 PTHR10027:SF28 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;ion channel activity#GO:0005216;potassium ion transmembrane transporter activity#GO:0015079;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;transporter activity#GO:0005215;channel activity#GO:0015267;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=6036|UniProtKB=Q01167 Q01167 FOXK2 PTHR45881:SF3 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED FORKHEAD BOX PROTEIN K2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=24809|UniProtKB=Q9Y2M2 Q9Y2M2 SSUH2 PTHR15852:SF56 PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN PROTEIN SSUH2 HOMOLOG HUMAN|HGNC=3482|UniProtKB=P38117 P38117 ETFB PTHR21294:SF8 ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA electron transfer activity#GO:0009055;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 HUMAN|HGNC=10777|UniProtKB=Q96HF1 Q96HF1 SFRP2 PTHR11309:SF45 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;non-canonical Wnt signaling pathway#GO:0035567;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434 HUMAN|HGNC=6305|UniProtKB=P33947 P33947 KDELR2 PTHR10585:SF37 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR 2 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=711|UniProtKB=P49407 P49407 ARRB1 PTHR11792:SF22 ARRESTIN BETA-ARRESTIN-1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;receptor internalization#GO:0031623;membrane organization#GO:0061024;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;endocytosis#GO:0006897;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;sensory perception#GO:0007600 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>beta-ARR1#P05925;Wnt signaling pathway#P00057>beta-arrestin#P01456;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723 HUMAN|HGNC=11521|UniProtKB=Q9UHF0 Q9UHF0 TAC3 PTHR15536:SF1 TACHYKININ-3 TACHYKININ-3 blood circulation#GO:0008015;regulation of biological quality#GO:0065008;regulation of blood pressure#GO:0008217;positive regulation of blood pressure#GO:0045777;system process#GO:0003008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;circulatory system process#GO:0003013 HUMAN|HGNC=17351|UniProtKB=Q99633 Q99633 PRPF18 PTHR13007:SF19 PRE-MRNA SPLICING FACTOR-RELATED PRE-MRNA-SPLICING FACTOR 18 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;heterocycle catabolic process#GO:0046700;ribonucleoprotein complex subunit organization#GO:0071826;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;RNA processing#GO:0006396;cellular nitrogen compound catabolic process#GO:0044270;mRNA 3'-end processing#GO:0031124;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;RNA 3'-end processing#GO:0031123;intracellular mRNA localization#GO:0008298;mRNA polyadenylation#GO:0006378;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular process#GO:0009987;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007;RNA splicing, via transesterification reactions#GO:0000375;cellular macromolecule catabolic process#GO:0044265 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Lsm2-8 complex#GO:0120115;intracellular#GO:0005622;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=12563|UniProtKB=P11172 P11172 UMPS PTHR19278:SF9 OROTATE PHOSPHORIBOSYLTRANSFERASE URIDINE 5'-MONOPHOSPHATE SYNTHASE transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;pyrimidine nucleobase metabolic process#GO:0006206;pyrimidine nucleotide biosynthetic process#GO:0006221;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 transferase#PC00220 De novo pyrimidine ribonucleotides biosythesis#P02740>Orotate phosphoribosyltransferase#P02922 HUMAN|HGNC=799|UniProtKB=P05023 P05023 ATP1A1 PTHR43294:SF9 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;potassium ion transport#GO:0006813;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;cellular monovalent inorganic cation homeostasis#GO:0030004;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725;export from cell#GO:0140352 primary active transporter#PC00068 HUMAN|HGNC=13877|UniProtKB=Q9BSA4 Q9BSA4 TTYH2 PTHR12424:SF6 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=17104|UniProtKB=Q4KMG0 Q4KMG0 CDON PTHR44170:SF1 PROTEIN SIDEKICK CELL ADHESION MOLECULE-RELATED/DOWN-REGULATED BY ONCOGENES HUMAN|HGNC=14355|UniProtKB=Q86YB8 Q86YB8 ERO1B PTHR12613:SF2 ERO1-RELATED ERO1-LIKE PROTEIN BETA isomerase activity#GO:0016853;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 oxidoreductase#PC00176 HUMAN|HGNC=26158|UniProtKB=Q96FG2 Q96FG2 ELMOD3 PTHR12771:SF2 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 3 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6192|UniProtKB=O60674 O60674 JAK2 PTHR45807:SF1 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK2 CCKR signaling map#P06959>JAK2#P07156;PI3 kinase pathway#P00048>JAK#P01176;Interferon-gamma signaling pathway#P00035>Jak2#P00952;PDGF signaling pathway#P00047>Jak#P01155;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>JAK#P00846;JAK/STAT signaling pathway#P00038>Jak#P01034 HUMAN|HGNC=4057|UniProtKB=P11413 P11413 G6PD PTHR23429:SF0 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE dehydrogenase#PC00092 HUMAN|HGNC=19013|UniProtKB=Q8WV44 Q8WV44 TRIM41 PTHR24103:SF659 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM41-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=11331|UniProtKB=P30874 P30874 SSTR2 PTHR24229:SF6 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 2 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cellular response to steroid hormone stimulus#GO:0071383;response to lipid#GO:0033993;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to lipid#GO:0071396;response to estradiol#GO:0032355;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to steroid hormone#GO:0048545 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=11602|UniProtKB=O15119 O15119 TBX3 PTHR11267:SF91 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 specification of symmetry#GO:0009799;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;heart looping#GO:0001947;central nervous system development#GO:0007417;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;heart development#GO:0007507;embryonic heart tube development#GO:0035050;determination of heart left/right asymmetry#GO:0061371;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;determination of bilateral symmetry#GO:0009855;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;determination of left/right symmetry#GO:0007368;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=7534|UniProtKB=P50539 P50539 MXI1 PTHR11969:SF13 MAX DIMERIZATION, MAD MAX-INTERACTING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=17022|UniProtKB=Q9UPZ3 Q9UPZ3 HPS5 PTHR23287:SF18 RUBY-EYE2-LIKE PROTEIN HERMANSKY-PUDLAK SYNDROME 5 PROTEIN HUMAN|HGNC=6093|UniProtKB=P14616 P14616 INSRR PTHR24416:SF338 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN RECEPTOR-RELATED PROTEIN signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;peptide hormone binding#GO:0017046;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;JNK cascade#GO:0007254;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;inositol lipid-mediated signaling#GO:0048017;protein kinase B signaling#GO:0043491;positive regulation of protein kinase B signaling#GO:0051897;multicellular organismal process#GO:0032501;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;phosphatidylinositol-mediated signaling#GO:0048015;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;chemical homeostasis#GO:0048878;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;phosphatidylinositol 3-kinase signaling#GO:0014065;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of phosphatidylinositol 3-kinase signaling#GO:0014066;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of protein kinase B signaling#GO:0051896;regulation of transferase activity#GO:0051338 membrane protein complex#GO:0098796;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;integral component of membrane#GO:0016021;axon#GO:0030424;transferase complex, transferring phosphorus-containing groups#GO:0061695;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882 HUMAN|HGNC=7413|UniProtKB=Q13126 Q13126 MTAP PTHR42679:SF4 S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotide kinase#PC00172 HUMAN|HGNC=9376|UniProtKB=Q13131 Q13131 PRKAA1 PTHR24343:SF306 SERINE/THREONINE KINASE 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 HUMAN|HGNC=11362|UniProtKB=P42224 P42224 STAT1 PTHR11801:SF18 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to external biotic stimulus#GO:0043207;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;defense response#GO:0006952;organic substance metabolic process#GO:0071704;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;type I interferon signaling pathway#GO:0060337;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;response to peptide hormone#GO:0043434;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;response to type I interferon#GO:0034340;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 p53 pathway feedback loops 2#P04398>Myc#P04649;PDGF signaling pathway#P00047>STAT#P01173;Oxidative stress response#P00046>Stat1#P01125;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832;JAK/STAT signaling pathway#P00038>STAT#P01027;Oxidative stress response#P00046>Myc#P01124;Ras Pathway#P04393>Stat 1/3#P04566;Interferon-gamma signaling pathway#P00035>STAT1#P00961;Angiogenesis#P00005>STAT1#P00218;Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561 HUMAN|HGNC=304|UniProtKB=P54107 P54107 CRISP1 PTHR10334:SF213 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=31374|UniProtKB=P60827 P60827 C1QTNF8 PTHR22923:SF61 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 8 HUMAN|HGNC=17340|UniProtKB=Q6P2Q9 Q6P2Q9 PRPF8 PTHR11140:SF0 PRE-MRNA SPLICING FACTOR PRP8 PRE-MRNA-PROCESSING-SPLICING FACTOR 8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;snRNA binding#GO:0017069;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=17128|UniProtKB=Q9BRY0 Q9BRY0 SLC39A3 PTHR11040:SF168 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP3 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;transition metal ion transport#GO:0000041;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=26639|UniProtKB=Q8NBI6 Q8NBI6 XXYLT1 PTHR46612:SF1 XYLOSIDE XYLOSYLTRANSFERASE 1 XYLOSIDE XYLOSYLTRANSFERASE 1 transferase#PC00220 HUMAN|HGNC=18901|UniProtKB=Q9HCY8 Q9HCY8 S100A14 PTHR11639:SF4 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A14 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;chemokine receptor binding#GO:0042379;binding#GO:0005488;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;response to lipid#GO:0033993;regulation of localization#GO:0032879;pattern recognition receptor signaling pathway#GO:0002221;toll-like receptor 4 signaling pathway#GO:0034142;positive regulation of cellular component movement#GO:0051272;positive regulation of leukocyte migration#GO:0002687;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;regulation of leukocyte migration#GO:0002685;myeloid leukocyte migration#GO:0097529;regulation of immune system process#GO:0002682;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;regulation of cellular component movement#GO:0051270;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;positive regulation of locomotion#GO:0040017;positive regulation of immune system process#GO:0002684;localization of cell#GO:0051674;cell communication#GO:0007154;cell motility#GO:0048870;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;positive regulation of leukocyte chemotaxis#GO:0002690;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;extracellular region#GO:0005576;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=30172|UniProtKB=Q7RTN6 Q7RTN6 STRADA PTHR48014:SF20 SERINE/THREONINE-PROTEIN KINASE FRAY2 STE20-RELATED KINASE ADAPTER PROTEIN ALPHA non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=15954|UniProtKB=Q96GM8 Q96GM8 TOE1 PTHR15092:SF37 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 TARGET OF EGR1 PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;snRNA binding#GO:0017069;exonuclease activity#GO:0004527;catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;3'-5' exonuclease activity#GO:0008408 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=2035|UniProtKB=O95500 O95500 CLDN14 PTHR12002:SF99 CLAUDIN CLAUDIN-14 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=28778|UniProtKB=Q5GH77 Q5GH77 XKR3 PTHR14297:SF9 MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER XK-RELATED PROTEIN 3 HUMAN|HGNC=21215|UniProtKB=Q9H6K1 Q9H6K1 ILRUN PTHR20930:SF0 OVARIAN CARCINOMA ANTIGEN CA125-RELATED PROTEIN ILRUN HUMAN|HGNC=3389|UniProtKB=P54756 P54756 EPHA5 PTHR24416:SF17 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 5 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;brain development#GO:0007420;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;central nervous system development#GO:0007417;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;forebrain development#GO:0030900;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;head development#GO:0060322;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;animal organ development#GO:0048513;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=26073|UniProtKB=Q9BVV8 Q9BVV8 FAM174C PTHR28607:SF2 EXPRESSED PROTEIN PROTEIN FAM174C cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=11369|UniProtKB=P02808 P02808 STATH PTHR15057:SF3 STATHERIN STATHERIN HUMAN|HGNC=30078|UniProtKB=Q96HR9 Q96HR9 REEP6 PTHR12300:SF133 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 6 membrane traffic protein#PC00150 HUMAN|HGNC=7610|UniProtKB=Q99972 Q99972 MYOC PTHR23192:SF33 OLFACTOMEDIN-RELATED MYOCILIN structural protein#PC00211 HUMAN|HGNC=4419|UniProtKB=P01148 P01148 GNRH1 PTHR10522:SF0 GONADOLIBERIN PROGONADOLIBERIN-1 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>GnRH#P06704 HUMAN|HGNC=9692|UniProtKB=P26022 P26022 PTX3 PTHR46943:SF1 PENTRAXIN-RELATED PROTEIN PTX3 PENTRAXIN-RELATED PROTEIN PTX3 complement binding#GO:0001848;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488 response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;immune response#GO:0006955;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=31286|UniProtKB=A6NHG9 A6NHG9 OR5H14 PTHR26452:SF96 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5H14 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=15912|UniProtKB=Q9UNZ2 Q9UNZ2 NSFL1C PTHR23333:SF24 UBX DOMAIN CONTAINING PROTEIN NSFL1 COFACTOR P47 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;membrane organization#GO:0061024;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;Golgi organization#GO:0007030;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;nuclear envelope organization#GO:0006998;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;autophagy#GO:0006914 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=14150|UniProtKB=Q8N461 Q8N461 FBXL16 PTHR13318:SF193 UNCHARACTERIZED F-BOX/LRR-REPEAT PROTEIN 16 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=2596|UniProtKB=P05177 P05177 CYP1A2 PTHR24299:SF7 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1A2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=14905|UniProtKB=Q8TE23 Q8TE23 TAS1R2 PTHR24061:SF517 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=6089|UniProtKB=Q9Y581 Q9Y581 INSL6 PTHR12004:SF1 RELAXIN INSULIN-LIKE PEPTIDE INSL6 peptide hormone#PC00179 HUMAN|HGNC=23468|UniProtKB=Q96IM9 Q96IM9 DYDC2 PTHR23356:SF3 DPY30-RELATED DPY30 DOMAIN-CONTAINING PROTEIN 2 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;histone methylation#GO:0016571;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein alkylation#GO:0008213;protein methylation#GO:0006479;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;histone H3-K4 methylation#GO:0051568;cellular protein metabolic process#GO:0044267;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;chromatin silencing at telomere#GO:0006348;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;histone lysine methylation#GO:0034968;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=25245|UniProtKB=Q86X24 Q86X24 HORMAD1 PTHR48225:SF1 HORMA DOMAIN-CONTAINING PROTEIN 1 HORMA DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=30656|UniProtKB=Q14602 Q14602 ID2B PTHR11723:SF18 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-2B-RELATED molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=7044|UniProtKB=P26572 P26572 MGAT1 PTHR10468:SF0 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1/ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=25954|UniProtKB=Q8TBK6 Q8TBK6 ZCCHC10 PTHR13491:SF0 ZCCHC10 PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10 HUMAN|HGNC=9823|UniProtKB=O75771 O75771 RAD51D PTHR46457:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;four-way junction DNA binding#GO:0000400;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;telomere organization#GO:0032200;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;M phase#GO:0000279;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;cell cycle phase#GO:0022403;anatomical structure homeostasis#GO:0060249;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;meiosis I cell cycle phase#GO:0098764;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;nuclear chromosome, telomeric region#GO:0000784;microtubule organizing center#GO:0005815;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular#GO:0005622;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;replication fork#GO:0005657 DNA metabolism protein#PC00009 HUMAN|HGNC=28848|UniProtKB=Q9NQ92 Q9NQ92 COPRS PTHR36461:SF1 COORDINATOR OF PRMT5 AND DIFFERENTIATION STIMULATOR COORDINATOR OF PRMT5 AND DIFFERENTIATION STIMULATOR protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;peptidyl-arginine methylation#GO:0018216;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone methylation#GO:0016571;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4976|UniProtKB=P50747 P50747 HLCS PTHR12835:SF5 BIOTIN PROTEIN LIGASE BIOTIN--PROTEIN LIGASE ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular protein modification process#GO:0006464 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 HUMAN|HGNC=12576|UniProtKB=Q16831 Q16831 UPP1 PTHR43691:SF10 URIDINE PHOSPHORYLASE URIDINE PHOSPHORYLASE 1 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 HUMAN|HGNC=14311|UniProtKB=O60285 O60285 NUAK1 PTHR24343:SF350 SERINE/THREONINE KINASE NUAK FAMILY SNF1-LIKE KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=32262|UniProtKB=P0C7W9 P0C7W9 FAM90A14P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=26149|UniProtKB=Q53LP3 Q53LP3 SOWAHC PTHR14491:SF4 UNCHARACTERIZED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHC HUMAN|HGNC=495|UniProtKB=Q9GZV1 Q9GZV1 ANKRD2 PTHR24126:SF3 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24220|UniProtKB=Q6P1N9 Q6P1N9 TATDN1 PTHR10060:SF45 TATD FAMILY DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE TATDN1-RELATED 3'-5'-exodeoxyribonuclease activity#GO:0008296;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;exodeoxyribonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;exodeoxyribonuclease activity, producing 5'-phosphomonoesters#GO:0016895;deoxyribonuclease activity#GO:0004536 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=27639|UniProtKB=Q69YU3 Q69YU3 ANKRD34A PTHR24156:SF4 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 34A HUMAN|HGNC=12023|UniProtKB=P56180 P56180 TPTE PTHR12305:SF60 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE TPTE2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 p53 pathway#P00059>PTEN#G01579;p53 pathway feedback loops 2#P04398>PTEN#G04714;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway#P00059>PTEN#P01480;Hypoxia response via HIF activation#P00030>PTEN#P00824;PI3 kinase pathway#P00048>PTEN#P01189;p53 pathway feedback loops 2#P04398>PTEN#P04658 HUMAN|HGNC=2865|UniProtKB=O43323 O43323 DHH PTHR11889:SF56 HEDGEHOG DESERT HEDGEHOG PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;gene expression#GO:0010467;cell communication#GO:0007154;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;signaling#GO:0023052;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=16863|UniProtKB=Q9NYF8 Q9NYF8 BCLAF1 PTHR15268:SF4 THRAP3/BCLAF1 BCL-2-ASSOCIATED TRANSCRIPTION FACTOR 1 nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=17539|UniProtKB=Q96T92 Q96T92 INSM2 PTHR15065:SF6 INSULINOMA-ASSOCIATED 1 INSULINOMA-ASSOCIATED PROTEIN 2 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229 HUMAN|HGNC=12940|UniProtKB=Q12901 Q12901 ZNF155 PTHR24377:SF430 IP01015P-RELATED ZINC FINGER PROTEIN 155 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=14049|UniProtKB=O60783 O60783 MRPS14 PTHR19836:SF19 30S RIBOSOMAL PROTEIN S14 28S RIBOSOMAL PROTEIN S14, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=30133|UniProtKB=Q8IY49 Q8IY49 MMD2 PTHR20855:SF107 ADIPOR/PROGESTIN RECEPTOR-RELATED MONOCYTE TO MACROPHAGE DIFFERENTIATION FACTOR 2 G-protein coupled receptor#PC00021 HUMAN|HGNC=14601|UniProtKB=O75521 O75521 ECI2 PTHR23310:SF72 ACYL-COA-BINDING PROTEIN, ACBP ENOYL-COA DELTA ISOMERASE 2 transfer/carrier protein#PC00219 HUMAN|HGNC=19574|UniProtKB=Q8NH01 Q8NH01 OR2T11 PTHR26453:SF173 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T11 transmembrane signal receptor#PC00197 HUMAN|HGNC=9356|UniProtKB=Q9HCU5 Q9HCU5 PREB PTHR23284:SF0 PROLACTIN REGULATORY ELEMENT BINDING PROTEIN PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;nucleoside-triphosphatase activity#GO:0017111 vesicle targeting, to, from or within Golgi#GO:0048199;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;Golgi vesicle budding#GO:0048194;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;secretion#GO:0046903;establishment of vesicle localization#GO:0051650;vesicle organization#GO:0016050;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;secretion by cell#GO:0032940;cellular component assembly#GO:0022607;vesicle localization#GO:0051648;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;regulation of cellular localization#GO:0060341;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=3266|UniProtKB=P20042 P20042 EIF2S2 PTHR23001:SF24 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=25243|UniProtKB=Q6ZRH7 Q6ZRH7 CATSPERG PTHR14327:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT GAMMA CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT GAMMA motile cilium#GO:0031514;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=25557|UniProtKB=Q9NVM4 Q9NVM4 PRMT7 PTHR11006:SF4 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 7 N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein modifying enzyme#PC00260 HUMAN|HGNC=397|UniProtKB=P22557 P22557 ALAS2 PTHR13693:SF58 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE, ERYTHROID-SPECIFIC, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 cellular aromatic compound metabolic process#GO:0006725;response to hypoxia#GO:0001666;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;porphyrin-containing compound metabolic process#GO:0006778;biosynthetic process#GO:0009058;heme biosynthetic process#GO:0006783;system development#GO:0048731;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;pigment biosynthetic process#GO:0046148;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;response to oxygen levels#GO:0070482;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152;myeloid cell differentiation#GO:0030099;tetrapyrrole metabolic process#GO:0033013;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;multicellular organism development#GO:0007275;response to decreased oxygen levels#GO:0036293;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;erythrocyte differentiation#GO:0030218;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cell development#GO:0048468;immune system process#GO:0002376;response to stimulus#GO:0050896;response to stress#GO:0006950;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;aromatic compound biosynthetic process#GO:0019438 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transaminase#PC00216 HUMAN|HGNC=1756|UniProtKB=Q12864 Q12864 CDH17 PTHR24027:SF419 CADHERIN-23 CADHERIN-17 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=25764|UniProtKB=Q9H9A7 Q9H9A7 RMI1 PTHR14790:SF15 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 RMI1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;meiotic chromosome separation#GO:0051307;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=10697|UniProtKB=P55735 P55735 SEC13 PTHR11024:SF2 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER PROTEIN SEC13 HOMOLOG endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;Golgi vesicle budding#GO:0048194;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;envelope#GO:0031975;membrane protein complex#GO:0098796;nuclear pore#GO:0005643;ER to Golgi transport vesicle membrane#GO:0012507;nucleus#GO:0005634;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=7717|UniProtKB=P19404 P19404 NDUFV2 PTHR10371:SF3 NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 respirasome#GO:0070469;plasma membrane respiratory chain complex I#GO:0045272;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;respiratory chain complex I#GO:0045271;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;NADH dehydrogenase complex#GO:0030964;plasma membrane#GO:0005886 dehydrogenase#PC00092 Parkinson disease#P00049>Complex I#P01237 HUMAN|HGNC=17854|UniProtKB=Q9HAU5 Q9HAU5 UPF2 PTHR12839:SF7 NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2 REGULATOR OF NONSENSE TRANSCRIPTS 2 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;polysome#GO:0005844;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=8727|UniProtKB=Q15154 Q15154 PCM1 PTHR14164:SF12 PERICENTRIOLAR MATERIAL 1-RELATED PERICENTRIOLAR MATERIAL 1 PROTEIN vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;microtubule anchoring#GO:0034453;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;peptide transport#GO:0015833;microtubule organizing center organization#GO:0031023;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;protein localization to cytoskeleton#GO:0044380;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=13918|UniProtKB=P48634 P48634 PRRC2A PTHR14038:SF5 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2A cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 RNA metabolism protein#PC00031 HUMAN|HGNC=23516|UniProtKB=Q96B45 Q96B45 BORCS7 PTHR31397:SF3 BLOC-1-RELATED COMPLEX SUBUNIT 7 BORSC7 BLOC-1-RELATED COMPLEX SUBUNIT 7 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=16405|UniProtKB=O43709 O43709 BUD23 PTHR12734:SF0 METHYLTRANSFERASE-RELATED 18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED catalytic activity, acting on RNA#GO:0140098;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 methyltransferase#PC00155 HUMAN|HGNC=10485|UniProtKB=Q15413 Q15413 RYR3 PTHR13715:SF16 RYANODINE RECEPTOR AND IP3 RECEPTOR RYANODINE RECEPTOR 3 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;metal ion binding#GO:0046872;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;cation binding#GO:0043169;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;calcium ion binding#GO:0005509;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;sequestering of calcium ion#GO:0051208;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;negative regulation of cellular process#GO:0048523;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;release of sequestered calcium ion into cytosol#GO:0051209;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;regulation of cellular localization#GO:0060341;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065;negative regulation of sequestering of calcium ion#GO:0051283 bounding membrane of organelle#GO:0098588;supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;vacuole#GO:0005773;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;non-membrane-bounded organelle#GO:0043228;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;sarcomere#GO:0030017;transmembrane transporter complex#GO:1902495;cytoplasmic vesicle membrane#GO:0030659;myofibril#GO:0030016;membrane protein complex#GO:0098796;sarcoplasmic reticulum#GO:0016529;intracellular vesicle#GO:0097708;Z disc#GO:0030018;sarcoplasm#GO:0016528;sarcoplasmic reticulum membrane#GO:0033017;ion channel complex#GO:0034702;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;contractile fiber#GO:0043292;cation channel complex#GO:0034703;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;I band#GO:0031674;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;CCKR signaling map#P06959>RYR1/2/3#P07088;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441 HUMAN|HGNC=16431|UniProtKB=Q9NY84 Q9NY84 VNN3 PTHR10609:SF4 BIOTINIDASE-RELATED VASCULAR NON-INFLAMMATORY MOLECULE 3 hydrolase#PC00121 HUMAN|HGNC=24009|UniProtKB=Q6UXV4 Q6UXV4 APOOL PTHR14564:SF3 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT MIC27 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cristae formation#GO:0042407;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=26102|UniProtKB=Q9H788 Q9H788 SH2D4A PTHR14388:SF5 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 4A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 defense/immunity protein#PC00090 HUMAN|HGNC=20937|UniProtKB=Q5GH70 Q5GH70 XKR9 PTHR16024:SF13 XK-RELATED PROTEIN XK-RELATED PROTEIN 9 cellular component biogenesis#GO:0044085;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;developmental process#GO:0032502;endomembrane system organization#GO:0010256;plasma membrane bounded cell projection organization#GO:0120036;lipid transport#GO:0006869;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anion transport#GO:0006820;apoptotic process#GO:0006915;lipid translocation#GO:0034204;cell death#GO:0008219;vesicle organization#GO:0016050;lipid localization#GO:0010876;phospholipid translocation#GO:0045332;cellular component assembly#GO:0022607;organophosphate ester transport#GO:0015748;phagocytosis#GO:0006909;organic anion transport#GO:0015711;ion transport#GO:0006811;endocytosis#GO:0006897;plasma membrane phospholipid scrambling#GO:0017121;vesicle-mediated transport#GO:0016192;programmed cell death#GO:0012501;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;phospholipid transport#GO:0015914;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;anatomical structure development#GO:0048856;biological regulation#GO:0065007;plasma membrane bounded cell projection assembly#GO:0120031;apoptotic cell clearance#GO:0043277 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=25490|UniProtKB=Q96HA8 Q96HA8 NTAQ1 PTHR13035:SF0 UNCHARACTERIZED PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular protein modification process#GO:0006464 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28473|UniProtKB=Q8NC60 Q8NC60 NOA1 PTHR46406:SF1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 HUMAN|HGNC=29192|UniProtKB=Q9UPP5 Q9UPP5 KIAA1107 PTHR22427:SF2 UNCHARACTERIZED AP2-INTERACTING CLATHRIN-ENDOCYTOSIS PROTEIN HUMAN|HGNC=23784|UniProtKB=Q9BTC8 Q9BTC8 MTA3 PTHR10865:SF6 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA3 repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription coactivator activity#GO:0003713;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=33605|UniProtKB=A6NHM9 A6NHM9 MOXD2P PTHR10157:SF31 DOPAMINE BETA HYDROXYLASE RELATED DBH-LIKE MONOOXYGENASE PROTEIN 2-RELATED cation binding#GO:0043169;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 cellular aromatic compound metabolic process#GO:0006725;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;catecholamine metabolic process#GO:0006584;biosynthetic process#GO:0009058;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;aromatic compound catabolic process#GO:0019439;regulation of neurotransmitter levels#GO:0001505;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;extracellular region#GO:0005576;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 hydroxylase#PC00122 HUMAN|HGNC=28328|UniProtKB=O60293 O60293 ZFC3H1 PTHR21563:SF3 UNCHARACTERIZED ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;exosome (RNase complex)#GO:0000178;intracellular organelle#GO:0043229 HUMAN|HGNC=16984|UniProtKB=Q59EK9 Q59EK9 RUNDC3A PTHR46251:SF4 RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3 RUN DOMAIN-CONTAINING PROTEIN 3A regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;signaling#GO:0023052;positive regulation of biological process#GO:0048518;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=23504|UniProtKB=Q86XD8 Q86XD8 ZFAND4 PTHR46728:SF1 AN1-TYPE ZINC FINGER PROTEIN 4 AN1-TYPE ZINC FINGER PROTEIN 4 HUMAN|HGNC=12697|UniProtKB=Q6UXI7 Q6UXI7 VIT PTHR24020:SF23 COLLAGEN ALPHA VITRIN positive regulation of cell-substrate adhesion#GO:0010811;biological adhesion#GO:0022610;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;extracellular matrix organization#GO:0030198;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cell adhesion#GO:0045785;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=6068|UniProtKB=P55103 P55103 INHBC PTHR11848:SF130 TGF-BETA FAMILY INHIBIN BETA C CHAIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=11375|UniProtKB=P48723 P48723 HSPA13 PTHR19375:SF169 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 13 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524;ATPase activity#GO:0016887 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;chaperone-mediated protein folding#GO:0061077;cellular response to organic substance#GO:0071310;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;'de novo' protein folding#GO:0006458;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Parkinson disease#P00049>Hsp70#P01208 HUMAN|HGNC=7856|UniProtKB=P16083 P16083 NQO2 PTHR10204:SF33 NAD P H OXIDOREDUCTASE-RELATED RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE] oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidoreductase#PC00176 HUMAN|HGNC=17729|UniProtKB=Q8NBZ7 Q8NBZ7 UXS1 PTHR43078:SF6 UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED UDP-GLUCURONIC ACID DECARBOXYLASE 1 nucleotide binding#GO:0000166;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 decarboxylase#PC00089 HUMAN|HGNC=17652|UniProtKB=Q9H237 Q9H237 PORCN PTHR13906:SF12 PORCUPINE PROTEIN-SERINE O-PALMITOLEOYLTRANSFERASE PORCUPINE transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;protein binding#GO:0005515;transferase activity#GO:0016740;Wnt-protein binding#GO:0017147;binding#GO:0005488;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;protein secretion#GO:0009306;peptide secretion#GO:0002790;lipid modification#GO:0030258;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;secretion#GO:0046903;signal release#GO:0023061;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein palmitoylation#GO:0018345;protein lipidation#GO:0006497;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;secretion by cell#GO:0032940;metabolic process#GO:0008152;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;cellular process#GO:0009987;peptide transport#GO:0015833;cell-cell signaling by wnt#GO:0198738;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;protein transport#GO:0015031;biological regulation#GO:0065007;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 acetyltransferase#PC00038 HUMAN|HGNC=11891|UniProtKB=P05452 P05452 CLEC3B PTHR22799:SF3 TETRANECTIN-RELATED TETRANECTIN system development#GO:0048731;biomineralization#GO:0110148;ossification#GO:0001503;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;biomineral tissue development#GO:0031214;bone mineralization#GO:0030282;tissue development#GO:0009888 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=25657|UniProtKB=Q5H9F3 Q5H9F3 BCORL1 PTHR24117:SF6 AGAP007537-PB BCL-6 COREPRESSOR-LIKE PROTEIN 1 HUMAN|HGNC=5031|UniProtKB=P09651 P09651 HNRNPA1 PTHR48026:SF2 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1-RELATED HUMAN|HGNC=26959|UniProtKB=A6NE52 A6NE52 WDR97 PTHR45532:SF1 WD REPEAT-CONTAINING PROTEIN 97 WD REPEAT-CONTAINING PROTEIN 97 HUMAN|HGNC=8294|UniProtKB=P58180 P58180 OR4D2 PTHR48002:SF62 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D2 transmembrane signal receptor#PC00197 HUMAN|HGNC=18263|UniProtKB=Q9UL25 Q9UL25 RAB21 PTHR24073:SF509 DRAB5-RELATED RAS-RELATED PROTEIN RAB-21 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=13096|UniProtKB=Q06730 Q06730 ZNF33A PTHR24376:SF188 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 33A DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=27960|UniProtKB=Q695T7 Q695T7 SLC6A19 PTHR11616:SF125 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 HUMAN|HGNC=11831|UniProtKB=O00142 O00142 TK2 PTHR10513:SF24 DEOXYNUCLEOSIDE KINASE THYMIDINE KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotide kinase#PC00172 HUMAN|HGNC=17908|UniProtKB=O43298 O43298 ZBTB43 PTHR24414:SF43 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 43 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=28613|UniProtKB=Q5TIA1 Q5TIA1 MEI1 PTHR12044:SF10 BCL2 INTERACTING MEDIATOR OF CELL DEATH MEIOSIS INHIBITOR PROTEIN 1 meiosis I cell cycle phase#GO:0098764;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;cellular component organization#GO:0016043;cellular process#GO:0009987;M phase#GO:0000279;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;meiotic cell cycle process#GO:1903046;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;cell cycle phase#GO:0022403;meiosis I#GO:0007127 HUMAN|HGNC=1727|UniProtKB=P30307 P30307 CDC25C PTHR10828:SF64 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 M-PHASE INDUCER PHOSPHATASE 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;meiotic cell cycle process#GO:1903046;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;positive regulation of biological process#GO:0048518;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle phase transition#GO:1901990;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;reproduction#GO:0000003;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 p53 pathway#P00059>Cdc25C#P04624 HUMAN|HGNC=3415|UniProtKB=P01588 P01588 EPO PTHR10370:SF0 ERYTHROPOIETIN ERYTHROPOIETIN binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=19985|UniProtKB=P53999 P53999 SUB1 PTHR13215:SF0 RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription, initiation#GO:2000142;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of transcription initiation from RNA polymerase II promoter#GO:0060260;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of transcription initiation from RNA polymerase II promoter#GO:0060261;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of DNA-templated transcription, initiation#GO:2000144;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 general transcription factor#PC00259 HUMAN|HGNC=4716|UniProtKB=P16403 P16403 H1-2 PTHR11467:SF86 HISTONE H1 HISTONE H1.2 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of chromatin silencing#GO:0031935;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of chromatin silencing#GO:0031936;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of chromatin organization#GO:1902275;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;chromosome condensation#GO:0030261;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of DNA recombination#GO:0000018;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone#PC00118 HUMAN|HGNC=28128|UniProtKB=Q6UX40 Q6UX40 TMEM107 PTHR34341:SF1 TRANSMEMBRANE PROTEIN 107 TRANSMEMBRANE PROTEIN 107 vesicle targeting, to, from or within Golgi#GO:0048199;non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 HUMAN|HGNC=752|UniProtKB=O43681 O43681 GET3 PTHR10803:SF3 ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE ATPASE GET3 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 transporter#PC00227 HUMAN|HGNC=1247|UniProtKB=P09871 P09871 C1S PTHR24255:SF18 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1S SUBCOMPONENT serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=25523|UniProtKB=Q3V6T2 Q3V6T2 CCDC88A PTHR18947:SF30 HOOK PROTEINS GIRDIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 membrane traffic protein#PC00150 HUMAN|HGNC=28795|UniProtKB=Q9BV19 Q9BV19 C1orf50 PTHR14553:SF1 UNCHARACTERIZED PROTEIN C1ORF50 SIMILAR TO CHROMOSOME 1 OPEN READING FRAME 50 HUMAN|HGNC=12473|UniProtKB=P63146 P63146 UBE2B PTHR24067:SF246 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 B ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;histone ubiquitination#GO:0016574;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;covalent chromatin modification#GO:0016569;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular protein catabolic process#GO:0044257;chromatin organization#GO:0006325;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=923|UniProtKB=O94766 O94766 B3GAT3 PTHR10896:SF9 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 3 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;chondroitin sulfate proteoglycan metabolic process#GO:0050654;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=31993|UniProtKB=Q86T75 Q86T75 NBPF11 PTHR14199:SF35 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 10-RELATED HUMAN|HGNC=40049|UniProtKB=A6NCL1 A6NCL1 GMNC PTHR13372:SF2 GEMININ GEMININ COILED-COIL DOMAIN-CONTAINING PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of DNA replication#GO:0008156;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA biosynthetic process#GO:0071897;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;regulation of cell cycle#GO:0051726;DNA replication#GO:0006260;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of DNA replication#GO:0006275;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11486|UniProtKB=P51809 P51809 VAMP7 PTHR21136:SF196 SNARE PROTEINS VESICLE-ASSOCIATED MEMBRANE PROTEIN 7 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 SNARE complex#GO:0031201;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular#GO:0005622 SNARE protein#PC00034 HUMAN|HGNC=26459|UniProtKB=Q6NT32 Q6NT32 CES5A PTHR11559:SF43 CARBOXYLESTERASE CARBOXYLESTERASE 5A hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 esterase#PC00097 HUMAN|HGNC=9890|UniProtKB=Q16576 Q16576 RBBP7 PTHR22850:SF82 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP7 HUMAN|HGNC=26561|UniProtKB=Q8NEK5 Q8NEK5 ZNF548 PTHR24377:SF730 IP01015P-RELATED ZINC FINGER PROTEIN 548 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=6456|UniProtKB=O76015 O76015 KRT38 PTHR23239:SF110 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA8 HUMAN|HGNC=12110|UniProtKB=A0A0A6YYC5 A0A0A6YYC5 TRAV14DV4 PTHR23267:SF318 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 14/DELTA VARIABLE 4 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=12861|UniProtKB=Q96NJ6 Q96NJ6 ZFP3 PTHR24381:SF272 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 3 HOMOLOG DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15351|UniProtKB=Q8NH42 Q8NH42 OR4K13 PTHR48002:SF139 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K13 transmembrane signal receptor#PC00197 HUMAN|HGNC=16256|UniProtKB=Q9H489 Q9H489 TSPY26P PTHR11875:SF108 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 3-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=5172|UniProtKB=O43593 O43593 HR PTHR12549:SF4 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE HAIRLESS nucleic acid binding#GO:0003676;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;catalytic activity, acting on a protein#GO:0140096 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;demethylation#GO:0070988;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;protein demethylation#GO:0006482;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=2240|UniProtKB=Q92905 Q92905 COPS5 PTHR10410:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 5 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;ubiquitin-like protein-specific protease activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229 translation initiation factor#PC00224 PDGF signaling pathway#P00047>c-Jun#P01163 HUMAN|HGNC=26663|UniProtKB=Q8NA66 Q8NA66 CNBD1 PTHR23011:SF32 UNCHARACTERIZED CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=11035|UniProtKB=Q96Q91 Q96Q91 SLC4A9 PTHR11453:SF52 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=25700|UniProtKB=Q9HA64 Q9HA64 FN3KRP PTHR12149:SF10 FRUCTOSAMINE 3 KINASE-RELATED PROTEIN KETOSAMINE-3-KINASE kinase#PC00137 HUMAN|HGNC=20715|UniProtKB=Q9NPA3 Q9NPA3 MID1IP1 PTHR14315:SF16 SPOT14 FAMILY MEMBER MID1-INTERACTING PROTEIN 1 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;lipid metabolic process#GO:0006629;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;lipid biosynthetic process#GO:0008610;regulation of metabolic process#GO:0019222;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=19661|UniProtKB=Q59H18 Q59H18 TNNI3K PTHR24166:SF48 ROLLING PEBBLES, ISOFORM B SERINE/THREONINE-PROTEIN KINASE TNNI3K HUMAN|HGNC=28721|UniProtKB=Q96D59 Q96D59 RNF183 PTHR22791:SF7 UNCHARACTERIZED E3 UBIQUITIN-PROTEIN LIGASE RNF183 HUMAN|HGNC=30951|UniProtKB=Q6ZNG1 Q6ZNG1 ZNF600 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28929|UniProtKB=Q7RTS7 Q7RTS7 KRT74 PTHR45616:SF5 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 74 HUMAN|HGNC=25517|UniProtKB=Q9H583 Q9H583 HEATR1 PTHR13457:SF1 BAP28 HEAT REPEAT-CONTAINING PROTEIN 1 snoRNA binding#GO:0030515;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;rRNA processing#GO:0006364;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;transcription, DNA-templated#GO:0006351;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;aromatic compound biosynthetic process#GO:0019438;maturation of SSU-rRNA#GO:0030490;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;transcription by RNA polymerase I#GO:0006360;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 HUMAN|HGNC=33853|UniProtKB=Q9H1A7 Q9H1A7 POLR2J3 PTHR13946:SF31 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A-RELATED catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=19012|UniProtKB=Q9Y5Q5 Q9Y5Q5 CORIN PTHR24270:SF2 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED ATRIAL NATRIURETIC PEPTIDE-CONVERTING ENZYME apolipoprotein#PC00052 HUMAN|HGNC=12032|UniProtKB=Q12933 Q12933 TRAF2 PTHR10131:SF21 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 2 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625;tumor necrosis factor receptor binding#GO:0005164;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of MAPK cascade#GO:0043408;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;positive regulation of protein modification process#GO:0031401;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;stress-activated MAPK cascade#GO:0051403;cellular protein metabolic process#GO:0044267;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of DNA-binding transcription factor activity#GO:0051091;positive regulation of protein metabolic process#GO:0051247;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;transcription, DNA-templated#GO:0006351;regulation of JNK cascade#GO:0046328;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;JNK cascade#GO:0007254;positive regulation of signaling#GO:0023056;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;tumor necrosis factor-mediated signaling pathway#GO:0033209;RNA biosynthetic process#GO:0032774;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of stress-activated MAPK cascade#GO:0032874;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of stress-activated protein kinase signaling cascade#GO:0070302;cellular macromolecule biosynthetic process#GO:0034645;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of stress-activated MAPK cascade#GO:0032872;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;protein K63-linked ubiquitination#GO:0070534 membrane protein complex#GO:0098796;receptor complex#GO:0043235;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 p53 pathway#P00059>TRAF#P04620;Apoptosis signaling pathway#P00006>TRAF2#P00306 HUMAN|HGNC=26051|UniProtKB=Q9NWY4 Q9NWY4 HPF1 PTHR13386:SF2 HISTONE PARYLATION FACTOR 1 HISTONE PARYLATION FACTOR 1 cation binding#GO:0043169;carbohydrate derivative binding#GO:0097367;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;histone binding#GO:0042393 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=12814|UniProtKB=P23025 P23025 XPA PTHR10142:SF0 DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;nucleobase-containing compound metabolic process#GO:0006139;cellular response to abiotic stimulus#GO:0071214;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;cellular response to light stimulus#GO:0071482;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleotide-excision repair, DNA incision#GO:0033683;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organelle organization#GO:0006996;chromosome organization#GO:0051276;response to UV#GO:0009411;cellular response to stress#GO:0033554;cellular response to environmental stimulus#GO:0104004;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;nucleotide-excision repair complex#GO:0000109;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 damaged DNA-binding protein#PC00086 HUMAN|HGNC=3508|UniProtKB=Q01844 Q01844 EWSR1 PTHR23238:SF3 RNA BINDING PROTEIN RNA-BINDING PROTEIN EWS transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=9304|UniProtKB=P63151 P63151 PPP2R2A PTHR11871:SF2 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B ALPHA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629 HUMAN|HGNC=8576|UniProtKB=Q15102 Q15102 PAFAH1B3 PTHR11852:SF2 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT GAMMA protein modifying enzyme#PC00260 HUMAN|HGNC=25474|UniProtKB=Q8TC92 Q8TC92 ENOX1 PTHR16001:SF6 ECTO-NOX DISULFIDE-THIOL EXCHANGER ECTO-NOX DISULFIDE-THIOL EXCHANGER 1 oxidoreductase#PC00176 HUMAN|HGNC=10680|UniProtKB=P31040 P31040 SDHA PTHR11632:SF51 SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL dehydrogenase#PC00092 HUMAN|HGNC=5654|UniProtKB=P01825 P01825 IGHV4-59 PTHR23266:SF323 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=7419|UniProtKB=P00395 P00395 MT-CO1 PTHR10422:SF18 CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;cellular metabolic process#GO:0044237;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;energy derivation by oxidation of organic compounds#GO:0015980;cation transmembrane transport#GO:0098655;localization#GO:0051179;establishment of localization#GO:0051234;respiratory electron transport chain#GO:0022904;oxidation-reduction process#GO:0055114;metabolic process#GO:0008152 oxidase#PC00175 HUMAN|HGNC=23319|UniProtKB=Q9Y2I2 Q9Y2I2 NTNG1 PTHR10574:SF28 NETRIN/LAMININ-RELATED NETRIN-G1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;dendrite development#GO:0016358;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;motor neuron axon guidance#GO:0008045;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 HUMAN|HGNC=14202|UniProtKB=Q9BR39 Q9BR39 JPH2 PTHR23085:SF26 GH28348P JUNCTOPHILIN-2 sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=1950|UniProtKB=P11229 P11229 CHRM1 PTHR24247:SF182 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M1 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;organic cyclic compound binding#GO:0097159;acetylcholine receptor activity#GO:0015464;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;acetylcholine binding#GO:0042166;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;negative regulation of intracellular signal transduction#GO:1902532;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;negative regulation of catalytic activity#GO:0043086;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935;negative regulation of molecular function#GO:0044092 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>mAChR1/3#P01069;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=18280|UniProtKB=Q86XS8 Q86XS8 RNF130 PTHR22765:SF40 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF130 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=27101|UniProtKB=Q5UE93 Q5UE93 PIK3R6 PTHR15593:SF1 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 6 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Endothelin signaling pathway#P00019>PI3K#P00577;EGF receptor signaling pathway#P00018>PI3K#P00557 HUMAN|HGNC=28527|UniProtKB=Q8N323 Q8N323 NXPE1 PTHR16165:SF3 BRUSH BORDER-RELATED NXPE FAMILY MEMBER 1 HUMAN|HGNC=12839|UniProtKB=O75191 O75191 XYLB PTHR10196:SF57 SUGAR KINASE XYLULOSE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 carbohydrate kinase#PC00065 Ascorbate degradation#P02729>L-xylulose kinase#P02849 HUMAN|HGNC=13592|UniProtKB=O94952 O94952 FBXO21 PTHR31350:SF21 SI:DKEY-261L7.2 F-BOX ONLY PROTEIN 21 HUMAN|HGNC=24058|UniProtKB=Q8N6Y0 Q8N6Y0 USHBP1 PTHR23347:SF5 COLORECTAL MUTANT CANCER PROTEIN MCC PROTEIN -RELATED USHER SYNDROME TYPE-1C PROTEIN-BINDING PROTEIN 1 HUMAN|HGNC=26653|UniProtKB=Q8IYL2 Q8IYL2 TRMT44 PTHR21210:SF0 UNCHARACTERIZED TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=25232|UniProtKB=Q5TI25 Q5TI25 NBPF14 PTHR14199:SF35 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 10-RELATED HUMAN|HGNC=25146|UniProtKB=A1A4F0 A1A4F0 SLC66A1L PTHR16201:SF42 SEVEN TRANSMEMBRANE PROTEIN 1-RELATED SOLUTE CARRIER FAMILY 66 MEMBER 1 LIKE intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=26829|UniProtKB=Q8N8D7 Q8N8D7 NKAIN3 PTHR13084:SF2 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 3 localization#GO:0051179;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of transport#GO:0051049;regulation of sodium ion transport#GO:0002028;establishment of localization#GO:0051234;regulation of metal ion transport#GO:0010959;ion transport#GO:0006811;transport#GO:0006810;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of localization#GO:0032879;cation transport#GO:0006812 HUMAN|HGNC=20846|UniProtKB=Q86YZ3 Q86YZ3 HRNR PTHR22571:SF25 FILAGGRIN-RELATED HORNERIN system development#GO:0048731;multicellular organismal homeostasis#GO:0048871;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of body fluid levels#GO:0050878;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;skin development#GO:0043588 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=12851|UniProtKB=P62258 P62258 YWHAE PTHR18860:SF67 14-3-3 PROTEIN 14-3-3 PROTEIN EPSILON scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 HUMAN|HGNC=6822|UniProtKB=O60476 O60476 MAN1A2 PTHR11742:SF40 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IB hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=8946|UniProtKB=O43692 O43692 PI15 PTHR10334:SF63 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 15 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=19733|UniProtKB=Q96QU8 Q96QU8 XPO6 PTHR21452:SF4 EXPORTIN-6 EXPORTIN-6 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein export from nucleus#GO:0006611;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;nuclear transport#GO:0051169 HUMAN|HGNC=8276|UniProtKB=Q9NQN1 Q9NQN1 OR2S2 PTHR26453:SF176 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2S2 transmembrane signal receptor#PC00197 HUMAN|HGNC=622|UniProtKB=Q92624 Q92624 APPBP2 PTHR46575:SF1 AMYLOID PROTEIN-BINDING PROTEIN 2 AMYLOID PROTEIN-BINDING PROTEIN 2 HUMAN|HGNC=27653|UniProtKB=Q6PIV7 Q6PIV7 SLC25A34 PTHR45928:SF3 RE38146P SOLUTE CARRIER FAMILY 25 MEMBER 34 HUMAN|HGNC=393|UniProtKB=Q9Y243 Q9Y243 AKT3 PTHR24356:SF190 SERINE/THREONINE-PROTEIN KINASE RAC-GAMMA SERINE/THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 Ras Pathway#P04393>AKT#P04570;Angiogenesis#P00005>Akt#P00223;p53 pathway feedback loops 2#P04398>AKT#P04665;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AKT#P00827;Hypoxia response via HIF activation#P00030>AKT#P00819;EGF receptor signaling pathway#P00018>Akt#P00551;p53 pathway#P00059>Akt#P01486;T cell activation#P00053>Akt#P01332;PI3 kinase pathway#P00048>PKB#P01179;Interleukin signaling pathway#P00036>PKB#P00973;Huntington disease#P00029>Akt#P00805;Apoptosis signaling pathway#P00006>AKT#P00260;p53 pathway by glucose deprivation#P04397>Akt#P04641;Endothelin signaling pathway#P00019>Akt#P00589;FGF signaling pathway#P00021>Akt#P00632 HUMAN|HGNC=1362|UniProtKB=Q9P0K9 Q9P0K9 FRRS1L PTHR46902:SF1 DOMON DOMAIN-CONTAINING PROTEIN FRRS1L DOMON DOMAIN-CONTAINING PROTEIN FRRS1L HUMAN|HGNC=34403|UniProtKB=A2RU49 A2RU49 HYKK PTHR21064:SF1 UNCHARACTERIZED HYDROXYLYSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 HUMAN|HGNC=1314|UniProtKB=Q6ICG6 Q6ICG6 KIAA0930 PTHR21477:SF13 ZGC:172139 ZGC:172139 HUMAN|HGNC=17234|UniProtKB=Q9BXX3 Q9BXX3 ANKRD30A PTHR24147:SF63 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 30A HUMAN|HGNC=16430|UniProtKB=Q9GZZ8 Q9GZZ8 LACRT PTHR40711:SF2 DERMCIDIN-RELATED EXTRACELLULAR GLYCOPROTEIN LACRITIN cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;regulation of cell population proliferation#GO:0042127;positive regulation of secretion#GO:0051047;transport#GO:0006810;positive regulation of cell population proliferation#GO:0008284;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;cell communication#GO:0007154;cell population proliferation#GO:0008283;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;secretion#GO:0046903;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=20990|UniProtKB=Q9C0D0 Q9C0D0 PHACTR1 PTHR12751:SF6 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;stress fiber assembly#GO:0043149;contractile actin filament bundle assembly#GO:0030038;actin filament bundle assembly#GO:0051017;localization of cell#GO:0051674;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cell motility#GO:0048870;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;locomotion#GO:0040011 phosphatase modulator#PC00184 HUMAN|HGNC=16472|UniProtKB=Q9UMX9 Q9UMX9 SLC45A2 PTHR19432:SF34 SUGAR TRANSPORTER MEMBRANE-ASSOCIATED TRANSPORTER PROTEIN solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;solute:cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=29413|UniProtKB=Q6NYC8 Q6NYC8 PPP1R18 PTHR21685:SF0 TON-B BOX DOMAIN PHOSTENSIN HUMAN|HGNC=12187|UniProtKB=A0A1B0GX78 A0A1B0GX78 TRBV12-5 PTHR23268:SF91 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 12-5 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=1773|UniProtKB=P11802 P11802 CDK4 PTHR24056:SF129 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 4 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=25374|UniProtKB=Q8N6S4 Q8N6S4 ANKRD13C PTHR12447:SF26 UNCHARACTERIZED WITH ANKYRIN REPEAT DOMAIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13C cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=32395|UniProtKB=Q5KSL6 Q5KSL6 DGKK PTHR11255:SF33 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE KAPPA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 HUMAN|HGNC=9153|UniProtKB=Q8N490 Q8N490 PNKD PTHR11935:SF116 BETA LACTAMASE DOMAIN HYDROLASE PNKD-RELATED HUMAN|HGNC=19305|UniProtKB=Q6NXT4 Q6NXT4 SLC30A6 PTHR46531:SF1 ZINC TRANSPORTER 6 ZINC TRANSPORTER 6 transporter#PC00227 HUMAN|HGNC=21652|UniProtKB=Q86WC4 Q86WC4 OSTM1 PTHR15644:SF2 OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1 OSTEOPETROSIS-ASSOCIATED TRANSMEMBRANE PROTEIN 1 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=8779|UniProtKB=Q13370 Q13370 PDE3B PTHR11347:SF29 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;protein binding#GO:0005515;protein kinase binding#GO:0019901;phosphoric diester hydrolase activity#GO:0008081;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric ester hydrolase activity#GO:0042578;kinase binding#GO:0019900 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;second-messenger-mediated signaling#GO:0019932;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phosphodiesterase#PC00185 HUMAN|HGNC=11714|UniProtKB=P28347 P28347 TEAD1 PTHR11834:SF4 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;hippo signaling#GO:0035329;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=18647|UniProtKB=Q8WWV3 Q8WWV3 RTN4IP1 PTHR11695:SF294 ALCOHOL DEHYDROGENASE RELATED RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL dehydrogenase#PC00092 HUMAN|HGNC=24785|UniProtKB=A6XGL0 A6XGL0 YJEFN3 PTHR13232:SF12 NAD(P)H-HYDRATE EPIMERASE YJEF N-TERMINAL DOMAIN-CONTAINING PROTEIN 3 isomerase activity#GO:0016853;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 epimerase/racemase#PC00096 HUMAN|HGNC=28456|UniProtKB=Q6PJG9 Q6PJG9 LRFN4 PTHR45842:SF3 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=26259|UniProtKB=Q5D1E8 Q5D1E8 ZC3H12A PTHR12876:SF10 N4BP1-RELATED ENDORIBONUCLEASE ZC3H12A catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;organic cyclic compound binding#GO:0097159;binding#GO:0005488;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;peptide biosynthetic process#GO:0043043;negative regulation of translation#GO:0017148;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;biosynthetic process#GO:0009058;cellular nitrogen compound catabolic process#GO:0044270;translation#GO:0006412;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of cellular catabolic process#GO:0031329;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 endoribonuclease#PC00094 HUMAN|HGNC=2073|UniProtKB=O14773 O14773 TPP1 PTHR14218:SF15 PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2 TRIPEPTIDYL-PEPTIDASE 1 serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203 HUMAN|HGNC=30314|UniProtKB=Q9UK61 Q9UK61 TASOR PTHR16207:SF1 UNCHARACTERIZED PROTEIN TASOR HUMAN|HGNC=11181|UniProtKB=P08294 P08294 SOD3 PTHR10003:SF77 SUPEROXIDE DISMUTASE CU-ZN -RELATED EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN] cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to toxic substance#GO:0009636;cellular response to stress#GO:0033554;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidoreductase#PC00176 HUMAN|HGNC=23825|UniProtKB=Q86TA1 Q86TA1 MOB3B PTHR22599:SF22 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3B kinase activator#PC00138 HUMAN|HGNC=4473|UniProtKB=Q15760 Q15760 GPR19 PTHR24243:SF224 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 19-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=16278|UniProtKB=Q9C029 Q9C029 TRIM7 PTHR24103:SF589 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM7 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=19752|UniProtKB=Q8N3X1 Q8N3X1 FNBP4 PTHR46697:SF1 FORMIN-BINDING PROTEIN 4 FORMIN-BINDING PROTEIN 4 HUMAN|HGNC=16505|UniProtKB=Q8WWM9 Q8WWM9 CYGB PTHR46783:SF1 CYTOGLOBIN CYTOGLOBIN HUMAN|HGNC=5661|UniProtKB=A0A0J9YXX1 A0A0J9YXX1 IGHV5-10-1 PTHR23266:SF348 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 5-10-1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=33722|UniProtKB=Q66K41 Q66K41 ZNF385C PTHR23067:SF6 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385C membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=33494|UniProtKB=Q5H943 Q5H943 CT83 PTHR38650:SF3 KITA-KYUSHU LUNG CANCER ANTIGEN 1 KITA-KYUSHU LUNG CANCER ANTIGEN 1 HUMAN|HGNC=30541|UniProtKB=A8K979 A8K979 ERI2 PTHR23044:SF61 3'-5' EXONUCLEASE ERI1-RELATED ERI1 EXORIBONUCLEASE 2 exoribonuclease#PC00099 HUMAN|HGNC=2727|UniProtKB=Q99489 Q99489 DDO PTHR11530:SF11 D-AMINO ACID OXIDASE D-ASPARTATE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidase#PC00175 HUMAN|HGNC=9295|UniProtKB=Q15435 Q15435 PPP1R7 PTHR45973:SF23 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7 phosphatase modulator#PC00184 HUMAN|Ensembl=ENSG00000283763|UniProtKB=A0A1W2PQF6 A0A1W2PQF6 ENSG00000283763 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=23671|UniProtKB=Q7Z4J2 Q7Z4J2 GLT6D1 PTHR10462:SF27 GLYCOSYLTRANSFERASE-RELATED GLYCOSYLTRANSFERASE 6 DOMAIN-CONTAINING PROTEIN 1-RELATED transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=9607|UniProtKB=P12272 P12272 PTHLH PTHR17223:SF0 PARATHYROID HORMONE-RELATED PARATHYROID HORMONE-RELATED PROTEIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;animal organ development#GO:0048513;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;regulation of catalytic activity#GO:0050790;regulation of cell differentiation#GO:0045595;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;ossification#GO:0001503;multicellular organism development#GO:0007275;cell communication#GO:0007154;chondrocyte differentiation#GO:0002062;connective tissue development#GO:0061448;cellular process#GO:0009987;tissue development#GO:0009888;regulation of response to stimulus#GO:0048583;cell development#GO:0048468;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;cartilage development#GO:0051216;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 peptide hormone#PC00179 HUMAN|HGNC=18858|UniProtKB=Q9H3S5 Q9H3S5 PIGM PTHR12886:SF0 PIG-M MANNOSYLTRANSFERASE GPI MANNOSYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;mannosyltransferase complex#GO:0031501;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=3391|UniProtKB=P29322 P29322 EPHA8 PTHR24416:SF339 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 8 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=23191|UniProtKB=Q8NA92 Q8NA92 THAP8 PTHR46927:SF2 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 8 HUMAN|HGNC=20304|UniProtKB=Q8TEF2 Q8TEF2 C10orf105 PTHR38325:SF1 MCG55969 GENE, 17455-RELATED HUMAN|HGNC=16905|UniProtKB=O60662 O60662 KLHL41 PTHR24412:SF146 KELCH PROTEIN KELCH-LIKE PROTEIN 41 scaffold/adaptor protein#PC00226 HUMAN|HGNC=5104|UniProtKB=O43365 O43365 HOXA3 PTHR45664:SF13 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-A3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18863|UniProtKB=Q9NS40 Q9NS40 KCNH7 PTHR10217:SF466 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 7 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=14683|UniProtKB=Q9Y2G5 Q9Y2G5 POFUT2 PTHR13398:SF0 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;fucosyltransferase activity#GO:0008417;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 glycosyltransferase#PC00111 HUMAN|HGNC=7827|UniProtKB=Q9BPW8 Q9BPW8 NIPSNAP1 PTHR21017:SF11 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|GeneID=113230|UniProtKB=Q96FF7 Q96FF7 MISP3 PTHR18839:SF4 MITOTIC INTERACTOR AND SUBSTRATE OF PLK1 MISP FAMILY MEMBER MISP FAMILY MEMBER 3 HUMAN|HGNC=30578|UniProtKB=Q8NEV8 Q8NEV8 EXPH5 PTHR21469:SF4 EXOPHILIN-5 EXOPHILIN-5 HUMAN|HGNC=11192|UniProtKB=Q9UN79 Q9UN79 SOX13 PTHR45789:SF4 FI18025P1 TRANSCRIPTION FACTOR SOX-13 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell fate commitment#GO:0045165;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18628|UniProtKB=Q9NY15 Q9NY15 STAB1 PTHR24038:SF8 STABILIN STABILIN-1 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=21638|UniProtKB=Q5SZL2 Q5SZL2 CEP85L PTHR31075:SF2 FAMILY NOT NAMED CENTROSOMAL PROTEIN OF 85 KDA-LIKE intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=5145|UniProtKB=P37235 P37235 HPCAL1 PTHR23055:SF79 CALCIUM BINDING PROTEINS HIPPOCALCIN-LIKE PROTEIN 1 HUMAN|HGNC=1226|UniProtKB=O14908 O14908 GIPC1 PTHR12259:SF4 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20182|UniProtKB=Q9NUM3 Q9NUM3 SLC39A9 PTHR16133:SF5 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED ZINC TRANSPORTER ZIP9 secondary carrier transporter#PC00258 HUMAN|HGNC=13911|UniProtKB=Q8IXT2 Q8IXT2 DMRTC2 PTHR12322:SF15 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR C2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;reproductive process#GO:0022414;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;sex differentiation#GO:0007548;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;developmental process involved in reproduction#GO:0003006;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism reproduction#GO:0032504;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;multi-organism process#GO:0051704;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=16454|UniProtKB=Q9GZQ4 Q9GZQ4 NMUR2 PTHR24243:SF14 G-PROTEIN COUPLED RECEPTOR NEUROMEDIN-U RECEPTOR 2 G-protein coupled receptor#PC00021 HUMAN|HGNC=19265|UniProtKB=Q86SS6 Q86SS6 SYT9 PTHR10024:SF180 SYNAPTOTAGMIN SYNAPTOTAGMIN-9 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;syntaxin binding#GO:0019905;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cation transport#GO:0006812;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;response to metal ion#GO:0010038;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of ion transport#GO:0043269;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=26922|UniProtKB=Q5T890 Q5T890 ERCC6L2 PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED HUMAN|HGNC=1941|UniProtKB=P26374 P26374 CHML PTHR11787:SF9 RAB GDP-DISSOCIATION INHIBITOR RAB PROTEINS GERANYLGERANYLTRANSFERASE COMPONENT A 2 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;localization#GO:0051179;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein prenylation#GO:0018342;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 G-protein modulator#PC00022 HUMAN|HGNC=26528|UniProtKB=Q96M95 Q96M95 CCDC42 PTHR21683:SF8 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 42 HUMAN|HGNC=9051|UniProtKB=P00750 P00750 PLAT PTHR24264:SF42 TRYPSIN-RELATED TISSUE-TYPE PLASMINOGEN ACTIVATOR serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;localization#GO:0051179;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;movement of cell or subcellular component#GO:0006928;protein metabolic process#GO:0019538;cell migration#GO:0016477;locomotion#GO:0040011;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 Plasminogen activating cascade#P00050>tPA#P01257;Blood coagulation#P00011>tPA#P00431;Plasminogen activating cascade#P00050>pro-tPA#P01249 HUMAN|HGNC=9453|UniProtKB=O43272 O43272 PRODH PTHR13914:SF22 PROLINE OXIDASE PROLINE DEHYDROGENASE 1, MITOCHONDRIAL nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidase#PC00175 Huntington disease#P00029>Proline oxidase#G01529 HUMAN|HGNC=32481|UniProtKB=Q8N813 Q8N813 C3orf56 PTHR31813:SF17 PROLINE-RICH PROTEIN 23B CHROMOSOME 3 OPEN READING FRAME 56 HUMAN|HGNC=7818|UniProtKB=Q02577 Q02577 NHLH2 PTHR13864:SF19 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED HELIX-LOOP-HELIX PROTEIN 2 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=26041|UniProtKB=Q9NX01 Q9NX01 TXNL4B PTHR12052:SF4 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4B U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 oxidoreductase#PC00176 HUMAN|HGNC=4931|UniProtKB=P04439 P04439 HLA-A PTHR16675:SF229 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;amide binding#GO:0033218;peptide binding#GO:0042277 immune response#GO:0006955;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;T cell mediated immunity#GO:0002456;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=11940|UniProtKB=Q13470 Q13470 TNK1 PTHR24418:SF263 TYROSINE-PROTEIN KINASE NON-RECEPTOR TYROSINE-PROTEIN KINASE TNK1 HUMAN|HGNC=25465|UniProtKB=Q5JUQ0 Q5JUQ0 FAM78A PTHR31655:SF3 FAMILY NOT NAMED PROTEIN FAM78A HUMAN|HGNC=18231|UniProtKB=Q9BYE9 Q9BYE9 CDHR2 PTHR24026:SF75 FAT ATYPICAL CADHERIN-RELATED CADHERIN-RELATED FAMILY MEMBER 2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=28735|UniProtKB=Q8IXM7 Q8IXM7 ODF3L1 PTHR21580:SF3 SHIPPO-1-RELATED OUTER DENSE FIBER PROTEIN 3-LIKE PROTEIN 1 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 structural protein#PC00211 HUMAN|HGNC=53888|UniProtKB=P0DPQ4 P0DPQ4 FAM243B PTHR35969:SF1 PROTEIN FAM243A-RELATED PROTEIN FAM243A-RELATED HUMAN|HGNC=17014|UniProtKB=Q00587 Q00587 CDC42EP1 PTHR15344:SF7 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 1 HUMAN|HGNC=6501|UniProtKB=P13473 P13473 LAMP2 PTHR11506:SF6 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 2 cellular localization#GO:0051641;macroautophagy#GO:0016236;protein targeting to vacuole#GO:0006623;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;response to extracellular stimulus#GO:0009991;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein-containing complex subunit organization#GO:0043933;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;establishment of protein localization to vacuole#GO:0072666;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;protein transport#GO:0015031;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;autophagy#GO:0006914;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;organonitrogen compound catabolic process#GO:1901565;protein targeting to lysosome#GO:0006622;process utilizing autophagic mechanism#GO:0061919;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular response to starvation#GO:0009267;cellular component disassembly#GO:0022411;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;autophagosome maturation#GO:0097352;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular response to stimulus#GO:0051716;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;establishment of protein localization to organelle#GO:0072594;organonitrogen compound metabolic process#GO:1901564;response to nutrient levels#GO:0031667;cellular process#GO:0009987;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;autophagosome#GO:0005776;integral component of organelle membrane#GO:0031301;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;lysosome#GO:0005764;intracellular#GO:0005622;late endosome#GO:0005770;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;cell periphery#GO:0071944;membrane#GO:0016020;lytic vacuole#GO:0000323;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=21165|UniProtKB=Q9Y3L5 Q9Y3L5 RAP2C PTHR24070:SF200 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2C GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 regulation of cellular component movement#GO:0051270;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;Ras protein signal transduction#GO:0007265;regulation of localization#GO:0032879;localization of cell#GO:0051674;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of cell motility#GO:2000146;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 HUMAN|HGNC=33775|UniProtKB=Q6UXT8 Q6UXT8 ALKAL1 PTHR28676:SF1 ALK AND LTK LIGAND 2-RELATED ALK AND LTK LIGAND 1 protein tyrosine kinase activity#GO:0004713;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;signaling receptor binding#GO:0005102;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;ERK1 and ERK2 cascade#GO:0070371;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 HUMAN|HGNC=38040|UniProtKB=A0A087WYE8 A0A087WYE8 IGHV1OR21-1 PTHR23266:SF100 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=22442|UniProtKB=Q2UY09 Q2UY09 COL28A1 PTHR24023:SF878 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXVIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=385|UniProtKB=P52895 P52895 AKR1C2 PTHR11732:SF153 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER C1-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;steroid binding#GO:0005496;lipid binding#GO:0008289;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;secondary metabolic process#GO:0019748;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid derivative metabolic process#GO:1901568;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;steroid metabolic process#GO:0008202;fatty acid metabolic process#GO:0006631;organic cyclic compound metabolic process#GO:1901360;unsaturated fatty acid metabolic process#GO:0033559;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|Ensembl=ENSG00000248109|UniProtKB=A0A1B0GUY1 A0A1B0GUY1 MARCOL PTHR24023:SF891 COLLAGEN ALPHA COLLAGEN ALPHA-1(XVII) CHAIN-RELATED structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=41909|UniProtKB=E0CX11 E0CX11 STMP1 PTHR47709:SF2 SHORT TRANSMEMBRANE MITOCHONDRIAL PROTEIN 1 SHORT TRANSMEMBRANE MITOCHONDRIAL PROTEIN 1 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=17068|UniProtKB=Q8WX93 Q8WX93 PALLD PTHR10075:SF30 BASIGIN RELATED PALLADIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=13464|UniProtKB=Q9NRX5 Q9NRX5 SERINC1 PTHR10383:SF15 SERINE INCORPORATOR SERINE INCORPORATOR 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 HUMAN|HGNC=22998|UniProtKB=Q7Z404 Q7Z404 TMC4 PTHR23302:SF45 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215 HUMAN|HGNC=11214|UniProtKB=Q9NPE6 Q9NPE6 SPAG4 PTHR12911:SF16 SAD1/UNC-84-LIKE PROTEIN-RELATED SPERM-ASSOCIATED ANTIGEN 4 PROTEIN molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;nuclear envelope organization#GO:0006998;cellular process#GO:0009987 envelope#GO:0031975;membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=4653|UniProtKB=P13984 P13984 GTF2F2 PTHR10445:SF0 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TFIIFbeta#P00667;Transcription regulation by bZIP transcription factor#P00055>TFIIFbeta#P01396 HUMAN|HGNC=20262|UniProtKB=Q8IX90 Q8IX90 SKA3 PTHR48118:SF1 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 3 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 3 HUMAN|HGNC=13996|UniProtKB=Q9NQV5 Q9NQV5 PRDM11 PTHR16515:SF11 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN-CONTAINING PROTEIN 11 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6561|UniProtKB=P09382 P09382 LGALS1 PTHR11346:SF97 GALECTIN GALECTIN-1 extracellular matrix binding#GO:0050840;protein binding#GO:0005515;carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=16263|UniProtKB=O14613 O14613 CDC42EP2 PTHR15344:SF4 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 2 HUMAN|HGNC=26256|UniProtKB=Q8TB73 Q8TB73 NDNF PTHR14619:SF1 NEURON-DERIVED NEUROTROPHIC FACTOR PROTEIN NDNF glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;extracellular matrix organization#GO:0030198;proteoglycan metabolic process#GO:0006029;chondroitin sulfate metabolic process#GO:0030204;cellular protein modification process#GO:0006464;chondroitin sulfate proteoglycan metabolic process#GO:0050654;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;glycoprotein metabolic process#GO:0009100;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=81|UniProtKB=Q12979 Q12979 ABR PTHR23182:SF5 BREAKPOINT CLUSTER REGION PROTEIN BCR ACTIVE BREAKPOINT CLUSTER REGION-RELATED PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein modulator#PC00022 HUMAN|HGNC=1006|UniProtKB=Q8WUZ0 Q8WUZ0 BCL7C PTHR12767:SF10 BCL7 RELATED B-CELL CLL/LYMPHOMA 7 PROTEIN FAMILY MEMBER C HUMAN|HGNC=32448|UniProtKB=Q6ZQN5 Q6ZQN5 FOXI2 PTHR11829:SF372 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN I2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=24297|UniProtKB=Q5TAG4 Q5TAG4 NBPF12 PTHR14199:SF35 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 10-RELATED HUMAN|HGNC=23628|UniProtKB=Q8NGU9 Q8NGU9 GPR150 PTHR24241:SF83 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 150-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=9858|UniProtKB=P47736 P47736 RAP1GAP PTHR15711:SF3 RAP GTPASE-ACTIVATING PROTEIN RAP1 GTPASE-ACTIVATING PROTEIN 1 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1GAP#P00737 HUMAN|HGNC=14640|UniProtKB=Q96J65 Q96J65 ABCC12 PTHR24223:SF10 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 9 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=12642|UniProtKB=P23763 P23763 VAMP1 PTHR45701:SF1 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 1 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular#GO:0005622;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Synaptic vesicle trafficking#P05734>Synaptobrevin#P05779;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 HUMAN|HGNC=15358|UniProtKB=Q8IXE1 Q8IXE1 OR4N5 PTHR48002:SF17 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4N5 transmembrane signal receptor#PC00197 HUMAN|HGNC=6525|UniProtKB=P31025 P31025 LCN1 PTHR11430:SF124 LIPOCALIN LIPOCALIN-1 binding#GO:0005488 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 HUMAN|HGNC=20493|UniProtKB=Q86TU7 Q86TU7 SETD3 PTHR13271:SF47 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE ACTIN-HISTIDINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein alkylation#GO:0008213;protein methylation#GO:0006479;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 methyltransferase#PC00155 HUMAN|HGNC=23151|UniProtKB=Q86UX7 Q86UX7 FERMT3 PTHR16160:SF1 FERMITIN 2-RELATED FERMITIN FAMILY HOMOLOG 3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular component biogenesis#GO:0044085;regulation of cell-cell adhesion#GO:0022407;platelet activation#GO:0030168;cell adhesion mediated by integrin#GO:0033627;biological adhesion#GO:0022610;protein-containing complex assembly#GO:0065003;homotypic cell-cell adhesion#GO:0034109;wound healing#GO:0042060;leukocyte cell-cell adhesion#GO:0007159;regulation of biological process#GO:0050789;platelet aggregation#GO:0070527;regulation of biological quality#GO:0065008;regulation of cell adhesion#GO:0030155;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;regulation of body fluid levels#GO:0050878;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;hemostasis#GO:0007599;coagulation#GO:0050817;cell activation#GO:0001775;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;response to wounding#GO:0009611;response to stress#GO:0006950;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161 HUMAN|HGNC=2942|UniProtKB=Q96DT5 Q96DT5 DNAH11 PTHR10676:SF263 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN 11, AXONEMAL pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement#GO:0003341 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;C2 axonemal microtubule#GO:1990720;B axonemal microtubule#GO:0097650;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;axonemal microtubule#GO:0005879 microtubule binding motor protein#PC00156 HUMAN|HGNC=25325|UniProtKB=Q6ZU64 Q6ZU64 CFAP65 PTHR46127:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65 structural protein#PC00211 HUMAN|HGNC=15608|UniProtKB=Q14978 Q14978 NOLC1 PTHR23216:SF1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 HUMAN|HGNC=13059|UniProtKB=Q14584 Q14584 ZNF266 PTHR24381:SF149 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 266 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=33910|UniProtKB=Q9UH36 Q9UH36 SRRD PTHR28626:SF3 SRR1-LIKE PROTEIN SRR1-LIKE PROTEIN circadian rhythm#GO:0007623;cellular process#GO:0009987;microtubule-based process#GO:0007017;rhythmic process#GO:0048511 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5005|UniProtKB=P35914 P35914 HMGCL PTHR42738:SF1 HYDROXYMETHYLGLUTARYL-COA LYASE HYDROXYMETHYLGLUTARYL-COA LYASE, MITOCHONDRIAL lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;fatty acid derivative metabolic process#GO:1901568;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 lyase#PC00144 HUMAN|HGNC=1611|UniProtKB=Q9NPB9 Q9NPB9 ACKR4 PTHR10489:SF733 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 4 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 HUMAN|HGNC=25184|UniProtKB=Q96L03 Q96L03 SPATA17 PTHR22706:SF0 UNCHARACTERIZED SPERMATOGENESIS-ASSOCIATED PROTEIN 17 HUMAN|HGNC=28045|UniProtKB=Q9NTI7 Q9NTI7 INKA2 PTHR28615:SF2 PAK4-INHIBITOR INKA1-RELATED PAK4-INHIBITOR INKA2 protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=31357|UniProtKB=Q86UW8 Q86UW8 HAPLN4 PTHR22804:SF11 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 4 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=285|UniProtKB=P08588 P08588 ADRB1 PTHR24248:SF54 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-1 ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 blood circulation#GO:0008015;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of blood vessel diameter#GO:0097746;regulation of system process#GO:0044057;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of blood pressure#GO:0045776;activation of adenylate cyclase activity#GO:0007190;regulation of anatomical structure size#GO:0090066;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;heart contraction#GO:0060047;cell communication#GO:0007154;regulation of systemic arterial blood pressure#GO:0003073;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of blood pressure#GO:0008217;regulation of cellular process#GO:0050794;positive regulation of blood pressure#GO:0045777;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;cAMP-mediated signaling#GO:0019933;heart process#GO:0003015;positive regulation of multicellular organismal process#GO:0051240;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Beta1 adrenergic receptor signaling pathway#P04377>Beta1#P04433 HUMAN|HGNC=25919|UniProtKB=Q969W8 Q969W8 ZNF566 PTHR24381:SF57 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 566 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|Gene=KV311_HUMAN|UniProtKB=P04433 P04433 IGKV3-11 PTHR23267:SF382 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-11-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=16618|UniProtKB=P82930 P82930 MRPS34 PTHR28589:SF1 28S RIBOSOMAL PROTEIN S34, MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S34, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 HUMAN|HGNC=25619|UniProtKB=Q96HE9 Q96HE9 PRR11 PTHR23330:SF9 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED PROLINE-RICH PROTEIN 11 cell cycle arrest#GO:0007050;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell cycle#GO:0045786;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle process#GO:0022402;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9346|UniProtKB=O75626 O75626 PRDM1 PTHR16515:SF26 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;histone deacetylase binding#GO:0042826;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell fate commitment#GO:0045165;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=43879|UniProtKB=P0DPI3 P0DPI3 CENPVL2 PTHR28620:SF8 CENTROMERE PROTEIN V CENTROMERE PROTEIN V-LIKE PROTEIN 2 HUMAN|HGNC=9600|UniProtKB=P43088 P43088 PTGFR PTHR11866:SF4 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN F2-ALPHA RECEPTOR signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;organic acid binding#GO:0043177;transmembrane signaling receptor activity#GO:0004888 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of intracellular signal transduction#GO:1902531;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 HUMAN|HGNC=14463|UniProtKB=Q8N1S5 Q8N1S5 SLC39A11 PTHR11040:SF158 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP11 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;transition metal ion transport#GO:0000041;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=7590|UniProtKB=Q15746 Q15746 MYLK PTHR47633:SF1 IMMUNOGLOBULIN MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 multicellular organismal process#GO:0032501;smooth muscle contraction#GO:0006939;muscle system process#GO:0003012;system process#GO:0003008;muscle contraction#GO:0006936 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cell leading edge#GO:0031252;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;cell division site#GO:0032153;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 HUMAN|HGNC=33830|UniProtKB=Q08AG7 Q08AG7 MZT1 PTHR28520:SF2 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;mitotic spindle assembly#GO:0090307;protein polymerization#GO:0051258;spindle assembly#GO:0051225;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;intracellular#GO:0005622;gamma-tubulin complex#GO:0000930;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=5582|UniProtKB=A0A0B4J1V0 A0A0B4J1V0 IGHV3-15 PTHR23266:SF313 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-15 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=16185|UniProtKB=P60602 P60602 ROMO1 PTHR28525:SF1 REACTIVE OXYGEN SPECIES MODULATOR 1 REACTIVE OXYGEN SPECIES MODULATOR 1 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;protein insertion into mitochondrial inner membrane#GO:0045039;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;protein insertion into membrane#GO:0051205;transmembrane transport#GO:0055085;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=3691|UniProtKB=P22455 P22455 FGFR4 PTHR24416:SF343 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 4 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;fibroblast growth factor binding#GO:0017134;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;lipid biosynthetic process#GO:0008610;regulation of intracellular signal transduction#GO:1902531;carboxylic acid biosynthetic process#GO:0046394;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;steroid metabolic process#GO:0008202;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;regulation of lipid biosynthetic process#GO:0046890;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;organic acid biosynthetic process#GO:0016053;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;enzyme linked receptor protein signaling pathway#GO:0007167;monocarboxylic acid biosynthetic process#GO:0072330;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of lipid metabolic process#GO:0019216;small molecule biosynthetic process#GO:0044283;positive regulation of ERK1 and ERK2 cascade#GO:0070374;steroid biosynthetic process#GO:0006694;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;lipid metabolic process#GO:0006629;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;carboxylic acid metabolic process#GO:0019752;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 HUMAN|HGNC=15009|UniProtKB=Q8NG85 Q8NG85 OR2L3 PTHR26453:SF680 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2L3 transmembrane signal receptor#PC00197 HUMAN|HGNC=17849|UniProtKB=Q96PE1 Q96PE1 ADGRA2 PTHR45930:SF1 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A2 signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of Wnt signaling pathway#GO:0030177;nervous system development#GO:0007399;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;vasculature development#GO:0001944;sprouting angiogenesis#GO:0002040;central nervous system development#GO:0007417;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;tube development#GO:0035295;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;response to stimulus#GO:0050896;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 G-protein coupled receptor#PC00021 HUMAN|HGNC=23106|UniProtKB=Q6NSW7 Q6NSW7 NANOGP8 PTHR24327:SF79 HOMEOBOX PROTEIN HOMEOBOX PROTEIN NANOG-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=24219|UniProtKB=O15446 O15446 POLR1G PTHR15484:SF8 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA34 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA34 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=23486|UniProtKB=Q9H0M4 Q9H0M4 ZCWPW1 PTHR15999:SF2 UNCHARACTERIZED ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 HUMAN|HGNC=7133|UniProtKB=O14686 O14686 KMT2D PTHR45888:SF2 HL01030P-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE 2D N-methyltransferase activity#GO:0008170;binding#GO:0005488;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;transcription coactivator activity#GO:0003713;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;histone binding#GO:0042393;histone-lysine N-methyltransferase activity#GO:0018024;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transferase activity#GO:0016740;protein binding#GO:0005515;molecular function regulator#GO:0098772;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=26005|UniProtKB=Q8IWV1 Q8IWV1 LAX1 PTHR24091:SF0 LYMPHOCYTE TRANSMEMBRANE ADAPTER 1 LYMPHOCYTE TRANSMEMBRANE ADAPTER 1 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;activation of immune response#GO:0002253;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;regulation of T cell activation#GO:0050863;leukocyte cell-cell adhesion#GO:0007159;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;intracellular signal transduction#GO:0035556;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;negative regulation of T cell activation#GO:0050868;lymphocyte activation#GO:0046649;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250;immune response-activating cell surface receptor signaling pathway#GO:0002429 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 defense/immunity protein#PC00090 HUMAN|HGNC=7110|UniProtKB=Q9BUB5 Q9BUB5 MKNK1 PTHR24349:SF114 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-INTERACTING SERINE/THREONINE-PROTEIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;protein autophosphorylation#GO:0046777;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 p38 MAPK pathway#P05918>MNK1#P06018;Oxidative stress response#P00046>MNK1/2#P01137;Interleukin signaling pathway#P00036>MNK1/2#P00972;PDGF signaling pathway#P00047>MNK1/2#P01149 HUMAN|HGNC=12470|UniProtKB=Q8TBC4 Q8TBC4 UBA3 PTHR10953:SF6 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 HUMAN|HGNC=5184|UniProtKB=Q9Y5N1 Q9Y5N1 HRH3 PTHR24247:SF194 5-HYDROXYTRYPTAMINE RECEPTOR HISTAMINE H3 RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;organic cyclic compound binding#GO:0097159;acetylcholine receptor activity#GO:0015464;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;acetylcholine binding#GO:0042166;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;negative regulation of intracellular signal transduction#GO:1902532;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;negative regulation of catalytic activity#GO:0043086;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935;negative regulation of molecular function#GO:0044092 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=1052|UniProtKB=O00499 O00499 BIN1 PTHR46514:SF4 AMPHIPHYSIN MYC BOX-DEPENDENT-INTERACTING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;binding#GO:0005488 presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=14258|UniProtKB=Q9Y5K6 Q9Y5K6 CD2AP PTHR14167:SF23 SH3 DOMAIN-CONTAINING CD2-ASSOCIATED PROTEIN HUMAN|HGNC=16115|UniProtKB=Q8WWY7 Q8WWY7 WFDC12 PTHR19441:SF42 WHEY ACDIC PROTEIN WAP WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 12 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antibacterial humoral response#GO:0019731;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=26916|UniProtKB=Q92802 Q92802 N4BP2L2 PTHR13308:SF23 UNCHARACTERIZED NEDD4-BINDING PROTEIN 2-LIKE 2 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28635|UniProtKB=Q6ZS86 Q6ZS86 GK5 PTHR10196:SF68 SUGAR KINASE GLYCEROL KINASE 5-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;triglyceride metabolic process#GO:0006641;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;cellular carbohydrate metabolic process#GO:0044262;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 carbohydrate kinase#PC00065 HUMAN|HGNC=14956|UniProtKB=Q8N387 Q8N387 MUC15 PTHR45427:SF1 MUCIN-15 MUCIN-15 HUMAN|HGNC=28145|UniProtKB=Q9BSR8 Q9BSR8 YIPF4 PTHR21236:SF7 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF4 HUMAN|HGNC=30024|UniProtKB=Q8IYB4 Q8IYB4 PEX5L PTHR10130:SF1 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 PEX5-RELATED PROTEIN signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein targeting to peroxisome#GO:0006625;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein localization to peroxisome#GO:0072662;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;microbody membrane#GO:0031903;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=18104|UniProtKB=Q8NES8 Q8NES8 DEFB124 PTHR47897:SF1 BETA-DEFENSIN 124 BETA-DEFENSIN 124 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of cellular component movement#GO:0051272;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;transcription, DNA-templated#GO:0006351;regulation of cell migration#GO:0030334;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;I-kappaB kinase/NF-kappaB signaling#GO:0007249;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;positive regulation of locomotion#GO:0040017;cellular response to biotic stimulus#GO:0071216;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;movement of cell or subcellular component#GO:0006928;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;cytokine production#GO:0001816;positive regulation of leukocyte migration#GO:0002687;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of NF-kappaB transcription factor activity#GO:0051092;response to bacterium#GO:0009617;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;regulation of leukocyte migration#GO:0002685;myeloid leukocyte migration#GO:0097529;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;macromolecule biosynthetic process#GO:0009059;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;positive regulation of immune system process#GO:0002684;cellular biosynthetic process#GO:0044249;cell motility#GO:0048870;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;cell chemotaxis#GO:0060326;positive regulation of DNA-binding transcription factor activity#GO:0051091;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of leukocyte chemotaxis#GO:0002690;cell migration#GO:0016477;regulation of cellular macromolecule biosynthetic process#GO:2000112 antimicrobial response protein#PC00051 HUMAN|HGNC=17039|UniProtKB=Q4ZIN3 Q4ZIN3 TMEM259 PTHR21650:SF4 MEMBRALIN/KINETOCHORE PROTEIN NUF2 MEMBRALIN regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stress#GO:0006950;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;regulation of response to stress#GO:0080134;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=27606|UniProtKB=Q86XF7 Q86XF7 ZNF575 PTHR23226:SF206 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 575 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21701|UniProtKB=Q6PJG6 Q6PJG6 BRAT1 PTHR21331:SF2 BRCA1-ASSOCIATED ATM ACTIVATOR 1 BRCA1-ASSOCIATED ATM ACTIVATOR 1 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular response to DNA damage stimulus#GO:0006974;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=500|UniProtKB=P15144 P15144 ANPEP PTHR11533:SF172 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE N cation binding#GO:0043169;metallopeptidase activity#GO:0008237;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;peptide binding#GO:0042277;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;peptidase activity#GO:0008233;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=8061|UniProtKB=Q9Y6R0 Q9Y6R0 NUMBL PTHR11232:SF32 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER NUMB-LIKE PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=30708|UniProtKB=P0C7X1 P0C7X1 TBC1D3H PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=8515|UniProtKB=Q9HC10 Q9HC10 OTOF PTHR12546:SF32 FER-1-LIKE OTOFERLIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167;binding#GO:0005488 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;plasma membrane organization#GO:0007009;transport#GO:0006810;protein-containing complex assembly#GO:0065003;endomembrane system organization#GO:0010256;regulated exocytosis#GO:0045055;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;presynaptic membrane#GO:0042734;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;synaptic membrane#GO:0097060;whole membrane#GO:0098805;presynaptic active zone#GO:0048786;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=12401|UniProtKB=P33981 P33981 TTK PTHR22974:SF21 MIXED LINEAGE PROTEIN KINASE DUAL SPECIFICITY PROTEIN KINASE TTK transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of sister chromatid segregation#GO:0033046;cellular localization#GO:0051641;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of nuclear division#GO:0051784;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of mitotic sister chromatid segregation#GO:0033047;reproductive process#GO:0022414;negative regulation of cellular component organization#GO:0051129;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;mitotic sister chromatid separation#GO:0051306;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;meiotic cell cycle#GO:0051321;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;reproduction#GO:0000003;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;mitotic cell cycle phase transition#GO:0044772;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;negative regulation of cell cycle process#GO:0010948;peptidyl-serine phosphorylation#GO:0018105;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;meiotic chromosome separation#GO:0051307;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;protein localization to kinetochore#GO:0034501;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;mitotic spindle assembly checkpoint#GO:0007094;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;protein localization to organelle#GO:0033365;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;mitotic cell cycle checkpoint#GO:0007093;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;metaphase/anaphase transition of cell cycle#GO:0044784;negative regulation of chromosome separation#GO:1905819;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;regulation of meiotic cell cycle#GO:0051445;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;peptidyl-serine modification#GO:0018209;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=6493|UniProtKB=Q13753 Q13753 LAMC2 PTHR10574:SF313 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-2 system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;tissue development#GO:0009888 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=10607|UniProtKB=P09683 P09683 SCT PTHR17378:SF1 SECRETIN SECRETIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 system process#GO:0003008;brain development#GO:0007420;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;nervous system development#GO:0007399;regulation of biological process#GO:0050789;positive regulation of peptide hormone secretion#GO:0090277;hormone secretion#GO:0046879;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of secretion#GO:0051046;central nervous system development#GO:0007417;hormone transport#GO:0009914;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of peptide hormone secretion#GO:0090276;regulation of multicellular organismal process#GO:0051239;positive regulation of secretion#GO:0051047;regulation of body fluid levels#GO:0050878;positive regulation of transport#GO:0051050;cell communication#GO:0007154;negative regulation of transport#GO:0051051;peptide transport#GO:0015833;positive regulation of hormone secretion#GO:0046887;positive regulation of cellular process#GO:0048522;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of secretion by cell#GO:1903532;export from cell#GO:0140352;regulation of peptide transport#GO:0090087;positive regulation of multicellular organismal process#GO:0051240;head development#GO:0060322;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;animal organ development#GO:0048513;regulation of signaling#GO:0023051;positive regulation of peptide secretion#GO:0002793;developmental process#GO:0032502;transport#GO:0006810;regulation of system process#GO:0044057;peptide secretion#GO:0002790;amide transport#GO:0042886;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;peptide hormone secretion#GO:0030072;regulation of hormone secretion#GO:0046883;signal release#GO:0023061;signaling#GO:0023052;cell-cell signaling#GO:0007267;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;digestion#GO:0007586;biological regulation#GO:0065007 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=2454|UniProtKB=Q9HCP0 Q9HCP0 CSNK1G1 PTHR11909:SF156 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;membrane organization#GO:0061024;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of Wnt signaling pathway#GO:0030177;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;vesicle organization#GO:0016050;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;localization#GO:0051179;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 HUMAN|HGNC=29106|UniProtKB=O94830 O94830 DDHD2 PTHR23509:SF7 PA-PL1 PHOSPHOLIPASE FAMILY PHOSPHOLIPASE DDHD2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi-associated vesicle#GO:0005798;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229 phospholipase#PC00186 HUMAN|HGNC=19388|UniProtKB=P49593 P49593 PPM1F PTHR13832:SF233 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1F hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of protein modification process#GO:0031399;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of proteolysis#GO:0045862;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;regulation of phosphorylation#GO:0042325;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of metabolic process#GO:0009893;positive regulation of programmed cell death#GO:0043068;cell death#GO:0008219;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of protein kinase activity#GO:0045859;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of cell death#GO:0010941;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell death#GO:0010942;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 HUMAN|HGNC=24795|UniProtKB=Q6ZS11 Q6ZS11 RINL PTHR23101:SF72 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR-LIKE PROTEIN guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=28206|UniProtKB=Q9BSD3 Q9BSD3 RHNO1 PTHR35541:SF1 RAD9, HUS1, RAD1-INTERACTING NUCLEAR ORPHAN PROTEIN 1 RAD9, HUS1, RAD1-INTERACTING NUCLEAR ORPHAN PROTEIN 1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;cellular macromolecule metabolic process#GO:0044260;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;DNA damage checkpoint#GO:0000077;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14059|UniProtKB=Q96J87 Q96J87 CELF6 PTHR24012:SF716 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 6 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11138|UniProtKB=P37840 P37840 SNCA PTHR13820:SF5 SYNUCLEIN ALPHA-SYNUCLEIN cation binding#GO:0043169;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;transition metal ion binding#GO:0046914 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;regulation of neuron death#GO:1901214;membrane organization#GO:0061024;transport#GO:0006810;neuron death#GO:0070997;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;cell death#GO:0008219;synaptic signaling#GO:0099536;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of cell death#GO:0010941;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;cytoplasm#GO:0005737;axon terminus#GO:0043679;cell body#GO:0044297;intracellular#GO:0005622;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cell projection#GO:0042995;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Parkinson disease#P00049>alpha-Synuclein#P01218 HUMAN|HGNC=10741|UniProtKB=O75326 O75326 SEMA7A PTHR11036:SF80 SEMAPHORIN SEMAPHORIN-7A integrin binding#GO:0005178;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cell adhesion molecule binding#GO:0050839;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein metabolic process#GO:0051246;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of cytokine production involved in immune response#GO:0002718;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;production of molecular mediator of immune response#GO:0002440;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;defense response#GO:0006952;positive regulation of cell development#GO:0010720;cellular protein metabolic process#GO:0044267;positive regulation of axonogenesis#GO:0050772;regulation of cellular component movement#GO:0051270;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;negative regulation of neuron differentiation#GO:0045665;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;positive regulation of neurogenesis#GO:0050769;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;positive regulation of cell communication#GO:0010647;regulation of defense response#GO:0031347;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;taxis#GO:0042330;positive regulation of cell growth#GO:0030307;signal transduction#GO:0007165;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;growth#GO:0040007;MAPK cascade#GO:0000165;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;inflammatory response#GO:0006954;cytokine production#GO:0001816;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;immune effector process#GO:0002252;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;negative regulation of response to stimulus#GO:0048585;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;regulation of inflammatory response#GO:0050727;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;positive regulation of cellular component organization#GO:0051130;neuron projection guidance#GO:0097485;regulation of protein modification process#GO:0031399;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;plasma membrane bounded cell projection organization#GO:0120036;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component movement#GO:0051272;regulation of phosphorus metabolic process#GO:0051174;positive regulation of immune response#GO:0050778;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;negative regulation of cellular component movement#GO:0051271;regulation of signal transduction#GO:0009966;integrin-mediated signaling pathway#GO:0007229;positive regulation of immune effector process#GO:0002699;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of growth#GO:0045927;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;macromolecule metabolic process#GO:0043170;positive regulation of locomotion#GO:0040017;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of cell projection organization#GO:0031344;regulation of production of molecular mediator of immune response#GO:0002700;movement of cell or subcellular component#GO:0006928;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;regulation of cell morphogenesis involved in differentiation#GO:0010769;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;positive regulation of cell projection organization#GO:0031346;macromolecule modification#GO:0043412;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;positive regulation of neuron differentiation#GO:0045666;ERK1 and ERK2 cascade#GO:0070371;developmental growth involved in morphogenesis#GO:0060560;regulation of response to external stimulus#GO:0032101;positive regulation of cell differentiation#GO:0045597;regulation of cell motility#GO:2000145;developmental growth#GO:0048589;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;cell growth#GO:0016049;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;positive regulation of cellular protein metabolic process#GO:0032270;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=21169|UniProtKB=Q8IXI1 Q8IXI1 RHOT2 PTHR24072:SF311 RHO FAMILY GTPASE MITOCHONDRIAL RHO GTPASE 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;organelle localization#GO:0051640;regulation of organelle organization#GO:0033043;transport#GO:0006810;microtubule-based movement#GO:0007018;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of mitochondrion organization#GO:0010821;regulation of cellular process#GO:0050794;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;mitochondrion organization#GO:0007005;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;organelle transport along microtubule#GO:0072384 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;integral component of mitochondrial outer membrane#GO:0031307 small GTPase#PC00208 HUMAN|HGNC=727|UniProtKB=Q5T4W7 Q5T4W7 ARTN PTHR12173:SF9 GDNF SUBFAMILY OF TGF-BETA FAMILY ARTEMIN binding#GO:0005488;receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 neurotrophic factor#PC00163 HUMAN|HGNC=9666|UniProtKB=P08575 P08575 PTPRC PTHR19134:SF449 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C protein phosphatase#PC00195 T cell activation#P00053>CD45#P01329;JAK/STAT signaling pathway#P00038>PTP#P01033;B cell activation#P00010>CD45#P00396 HUMAN|HGNC=9596|UniProtKB=P35408 P35408 PTGER4 PTHR11866:SF6 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP4 SUBTYPE signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;organic acid binding#GO:0043177;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;divalent inorganic cation homeostasis#GO:0072507;positive regulation of cytosolic calcium ion concentration#GO:0007204;negative regulation of inflammatory response#GO:0050728;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;defense response#GO:0006952;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular cation homeostasis#GO:0030003;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;regulation of response to stimulus#GO:0048583;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to stress#GO:0006950;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;response to lipid#GO:0033993;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;cellular response to lipid#GO:0071396;inflammatory response#GO:0006954;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular chemical homeostasis#GO:0055082;regulation of inflammatory response#GO:0050727;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;cyclic-nucleotide-mediated signaling#GO:0019935 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 HUMAN|HGNC=25697|UniProtKB=P57764 P57764 GSDMD PTHR16399:SF15 GASDERMIN GASDERMIN-D phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;defense response#GO:0006952 inflammasome complex#GO:0061702;cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=15889|UniProtKB=Q9BQL6 Q9BQL6 FERMT1 PTHR16160:SF12 FERMITIN 2-RELATED FERMITIN FAMILY HOMOLOG 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;biological adhesion#GO:0022610 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 HUMAN|HGNC=6233|UniProtKB=P48547 P48547 KCNC1 PTHR11537:SF87 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;cell leading edge#GO:0031252;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;cell body#GO:0044297;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=33258|UniProtKB=B7Z6K7 B7Z6K7 ZNF814 PTHR24376:SF146 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 814 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29372|UniProtKB=Q5JYT7 Q5JYT7 KIAA1755 PTHR45845:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED SIMILAR TO HYPOTHETICAL PROTEIN D630003M21 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=13799|UniProtKB=P30040 P30040 ERP29 PTHR12211:SF1 ENDOPLASMIC RETICULUM PROTEIN ERP29 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 29 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=15036|UniProtKB=Q8NGX9 Q8NGX9 OR6P1 PTHR26453:SF73 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6P1 transmembrane signal receptor#PC00197 HUMAN|HGNC=6967|UniProtKB=Q99750 Q99750 MDFI PTHR15304:SF1 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR HUMAN|HGNC=17889|UniProtKB=Q9UBZ4 Q9UBZ4 APEX2 PTHR22748:SF4 AP ENDONUCLEASE DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 2 3'-5'-exodeoxyribonuclease activity#GO:0008296;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;exodeoxyribonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;exodeoxyribonuclease activity, producing 5'-phosphomonoesters#GO:0016895;phosphoric ester hydrolase activity#GO:0042578;deoxyribonuclease activity#GO:0004536 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25156|UniProtKB=Q96ES7 Q96ES7 SGF29 PTHR21539:SF0 UNCHARACTERIZED SAGA-ASSOCIATED FACTOR 29 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 histone H3 acetylation#GO:0043966;peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DUBm complex#GO:0071819 HUMAN|HGNC=8681|UniProtKB=Q9UN67 Q9UN67 PCDHB10 PTHR24028:SF54 CADHERIN-87A PROTOCADHERIN BETA-10 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=6993|UniProtKB=Q02078 Q02078 MEF2A PTHR11945:SF637 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2A cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;histone deacetylase binding#GO:0042826;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;Oxidative stress response#P00046>MEF-2#P01128 HUMAN|HGNC=19366|UniProtKB=Q9NVE7 Q9NVE7 PANK4 PTHR12280:SF20 PANTOTHENATE KINASE 4'-PHOSPHOPANTETHEINE PHOSPHATASE kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 HUMAN|HGNC=26804|UniProtKB=Q8N8Q1 Q8N8Q1 CYB561D1 PTHR15422:SF9 OS05G0565100 PROTEIN CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN 1 tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 HUMAN|HGNC=964|UniProtKB=O75936 O75936 BBOX1 PTHR10696:SF33 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED GAMMA-BUTYROBETAINE DIOXYGENASE nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 hydroxylase#PC00122 HUMAN|HGNC=8268|UniProtKB=Q96R28 Q96R28 OR2M2 PTHR26453:SF639 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2M2 transmembrane signal receptor#PC00197 HUMAN|HGNC=8931|UniProtKB=P15735 P15735 PHKG2 PTHR24347:SF390 SERINE/THREONINE-PROTEIN KINASE PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, LIVER/TESTIS ISOFORM non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 HUMAN|HGNC=1329|UniProtKB=Q6PML9 Q6PML9 SLC30A9 PTHR13414:SF9 HUEL-CATION TRANSPORTER ZINC TRANSPORTER 9 transporter#PC00227 HUMAN|HGNC=29932|UniProtKB=Q13057 Q13057 COASY PTHR10695:SF54 DEPHOSPHO-COA KINASE-RELATED BIFUNCTIONAL COENZYME A SYNTHASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886 HUMAN|HGNC=6290|UniProtKB=Q92952 Q92952 KCNN1 PTHR10153:SF38 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;calmodulin binding#GO:0005516;transporter activity#GO:0005215;channel activity#GO:0015267;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=8133|UniProtKB=P78380 P78380 OLR1 PTHR47298:SF1 OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 molecular adaptor activity#GO:0060090;low-density lipoprotein particle binding#GO:0030169;protein-containing complex binding#GO:0044877;binding#GO:0005488 macromolecule metabolic process#GO:0043170;biological adhesion#GO:0022610;organonitrogen compound metabolic process#GO:1901564;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;inflammatory response#GO:0006954;leukocyte cell-cell adhesion#GO:0007159;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cell death#GO:0008219;lipoprotein metabolic process#GO:0042157;defense response#GO:0006952;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=12953|UniProtKB=P49910 P49910 ZNF165 PTHR23226:SF61 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 165 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21071|UniProtKB=Q6PHW0 Q6PHW0 IYD PTHR23026:SF90 NADPH NITROREDUCTASE IODOTYROSINE DEIODINASE 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198 HUMAN|HGNC=12397|UniProtKB=Q15361 Q15361 TTF1 PTHR46760:SF1 TRANSCRIPTION TERMINATION FACTOR 1 TRANSCRIPTION TERMINATION FACTOR 1 binding#GO:0005488;chromatin binding#GO:0003682 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 General transcription by RNA polymerase I#P00022>TTF-I#P00654;General transcription regulation#P00023>TTF2#P00661;Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 HUMAN|HGNC=44208|UniProtKB=Q6UX82 Q6UX82 LYPD8 PTHR20914:SF2 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;defense response to Gram-negative bacterium#GO:0050829;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 HUMAN|HGNC=1791|UniProtKB=Q16667 Q16667 CDKN3 PTHR23339:SF103 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE CYCLIN-DEPENDENT KINASE INHIBITOR 3 protein phosphatase#PC00195 HUMAN|HGNC=16442|UniProtKB=Q15391 Q15391 P2RY14 PTHR24233:SF3 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 14 nucleotide binding#GO:0000166;signaling receptor activity#GO:0038023;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=32327|UniProtKB=Q96LR2 Q96LR2 LURAP1 PTHR33767:SF2 FAMILY NOT NAMED LEUCINE RICH ADAPTOR PROTEIN 1 HUMAN|HGNC=18024|UniProtKB=A1L4K1 A1L4K1 FSD2 PTHR24099:SF6 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 2 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=22422|UniProtKB=Q7Z4H9 Q7Z4H9 FAM220A PTHR31980:SF1 PROTEIN FAM220A PROTEIN FAM220A protein binding#GO:0005515;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10299|UniProtKB=P62906 P62906 RPL10A PTHR23105:SF185 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER 60S RIBOSOMAL PROTEIN L10A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=1358|UniProtKB=P02748 P02748 C9 PTHR45742:SF3 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C9 HUMAN|HGNC=3380|UniProtKB=Q9Y2J2 Q9Y2J2 EPB41L3 PTHR23280:SF20 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 HUMAN|HGNC=1843|UniProtKB=Q9BXW7 Q9BXW7 HDHD5 PTHR14269:SF17 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING 5 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transferase#PC00220 HUMAN|HGNC=8173|UniProtKB=O60403 O60403 OR10H2 PTHR24247:SF122 5-HYDROXYTRYPTAMINE RECEPTOR OLFACTORY RECEPTOR 10H1-RELATED cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=6184|UniProtKB=Q9NZM3 Q9NZM3 ITSN2 PTHR11216:SF29 EH DOMAIN INTERSECTIN-2 molecular adaptor activity#GO:0060090;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;receptor-mediated endocytosis#GO:0006898;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;synaptic membrane#GO:0097060;vesicle#GO:0031982;presynaptic membrane#GO:0042734;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=7864|UniProtKB=O43402 O43402 EMC8 PTHR12941:SF13 ER MEMBRANE PROTEIN COMPLEX ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8 membrane protein complex#GO:0098796;ER membrane protein complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=349|UniProtKB=P02765 P02765 AHSG PTHR13814:SF6 FETUIN ALPHA-2-HS-GLYCOPROTEIN peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=29484|UniProtKB=Q8NFU7 Q8NFU7 TET1 PTHR23358:SF2 UNCHARACTERIZED METHYLCYTOSINE DIOXYGENASE TET1 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;demethylation#GO:0070988;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;oxidative demethylation#GO:0070989;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28290|UniProtKB=Q5VUD6 Q5VUD6 DIPK1B PTHR21093:SF3 UNCHARACTERIZED DIVERGENT PROTEIN KINASE DOMAIN 1B HUMAN|HGNC=30401|UniProtKB=Q8WVC0 Q8WVC0 LEO1 PTHR23146:SF0 LEO1 PROTEIN RNA POLYMERASE-ASSOCIATED PROTEIN LEO1 basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of transcription elongation from RNA polymerase II promoter#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of DNA-templated transcription, elongation#GO:0032784;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;regulation of transcription elongation from RNA polymerase II promoter#GO:0034243;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;transcription elongation from RNA polymerase II promoter#GO:0006368;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=25806|UniProtKB=Q8NEC7 Q8NEC7 GSTCD PTHR13369:SF0 UNCHARACTERIZED GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=33156|UniProtKB=Q17RB0 Q17RB0 RTL8B PTHR15503:SF6 LDOC1 RELATED RETROTRANSPOSON GAG-LIKE PROTEIN 8A-RELATED intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=23532|UniProtKB=Q9H987 Q9H987 SYNPO2L PTHR24217:SF10 PUTATIVE-RELATED SYNAPTOPODIN 2-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;positive regulation of cytoskeleton organization#GO:0051495;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;actin cytoskeleton organization#GO:0030036;positive regulation of biological process#GO:0048518 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=2661|UniProtKB=O75553 O75553 DAB1 PTHR11232:SF40 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER DISABLED HOMOLOG 1 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;nervous system development#GO:0007399;localization#GO:0051179;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron migration#GO:0001764;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;generation of neurons#GO:0048699;cell migration#GO:0016477;locomotion#GO:0040011 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=7821|UniProtKB=P14543 P14543 NID1 PTHR46513:SF6 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED NIDOGEN-1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=34444|UniProtKB=Q3C1V1 Q3C1V1 C11orf91 PTHR36288:SF1 SIMILAR TO RIKEN CDNA A930018P22 SIMILAR TO RIKEN CDNA A930018P22 HUMAN|HGNC=7330|UniProtKB=O43347 O43347 MSI1 PTHR48032:SF3 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 RNA-BINDING PROTEIN MUSASHI HOMOLOG 1 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;polysome#GO:0005844;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=20407|UniProtKB=Q96L12 Q96L12 CALR3 PTHR11073:SF3 CALRETICULIN AND CALNEXIN CALRETICULIN-3 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;protein folding#GO:0006457;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 chaperone#PC00072 HUMAN|HGNC=19317|UniProtKB=Q8IVL5 Q8IVL5 P3H2 PTHR14049:SF1 LEPRECAN 1 PROLYL 3-HYDROXYLASE 2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=21557|UniProtKB=Q8IXY8 Q8IXY8 PPIL6 PTHR11071:SF526 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 6-RELATED chaperone#PC00072 HUMAN|HGNC=12917|UniProtKB=P52736 P52736 ZNF133 PTHR24381:SF119 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 133 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7614|UniProtKB=P54296 P54296 MYOM2 PTHR13817:SF22 TITIN MYOMESIN-2 HUMAN|HGNC=817|UniProtKB=P23634 P23634 ATP2B4 PTHR24093:SF435 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 4 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;binding#GO:0005488;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=20192|UniProtKB=Q9H0R1 Q9H0R1 AP5M1 PTHR16082:SF2 AP-5 COMPLEX SUBUNIT MU-1 AP-5 COMPLEX SUBUNIT MU-1 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;membrane coat#GO:0030117;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=4092|UniProtKB=Q99259 Q99259 GAD1 PTHR45677:SF5 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 1 decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 HUMAN|HGNC=31839|UniProtKB=A8MTQ0 A8MTQ0 NOTO PTHR24339:SF28 HOMEOBOX PROTEIN EMX-RELATED HOMEOBOX PROTEIN NOTOCHORD cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=11401|UniProtKB=Q96PF2 Q96PF2 TSSK2 PTHR24343:SF120 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE/THREONINE-PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=4252|UniProtKB=A6NGU5 A6NGU5 GGT3P PTHR11686:SF56 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 1 PROENZYME-RELATED transferase activity, transferring acyl groups#GO:0016746;hydrolase activity#GO:0016787;transferase activity#GO:0016740;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of response to external stimulus#GO:0032101;sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of inflammatory response#GO:0050727;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;regulation of defense response#GO:0031347;biological regulation#GO:0065007;catabolic process#GO:0009056;regulation of immune system process#GO:0002682;organic substance catabolic process#GO:1901575;defense response#GO:0006952;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190 HUMAN|HGNC=26477|UniProtKB=Q96MV1 Q96MV1 TLCD4 PTHR13439:SF1 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 4 biological regulation#GO:0065007;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=12646|UniProtKB=O95183 O95183 VAMP5 PTHR47462:SF1 VESICLE-ASSOCIATED MEMBRANE PROTEIN 5 VESICLE-ASSOCIATED MEMBRANE PROTEIN 5 protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;protein localization to cell periphery#GO:1990778;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=12936|UniProtKB=Q13105 Q13105 ZBTB17 PTHR24399:SF8 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23647|UniProtKB=Q9BY15 Q9BY15 ADGRE3 PTHR12011:SF455 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=9934|UniProtKB=Q15293 Q15293 RCN1 PTHR10827:SF17 RETICULOCALBIN RETICULOCALBIN-1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 calmodulin-related#PC00061 HUMAN|HGNC=25464|UniProtKB=Q8NAA4 Q8NAA4 ATG16L2 PTHR19878:SF7 AUTOPHAGY PROTEIN 16-LIKE PROTEIN ATG16L2 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;autophagosome organization#GO:1905037;protein metabolic process#GO:0019538;autophagy#GO:0006914;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;whole membrane#GO:0098805 HUMAN|HGNC=14910|UniProtKB=Q9NYW6 Q9NYW6 TAS2R3 PTHR11394:SF49 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=18262|UniProtKB=Q8IWA4 Q8IWA4 MFN1 PTHR10465:SF2 TRANSMEMBRANE GTPASE FZO1 MITOFUSIN-1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;mitochondrial fusion#GO:0008053;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;organelle localization#GO:0051640;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;organelle fusion#GO:0048284 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=26309|UniProtKB=Q86VU5 Q86VU5 COMTD1 PTHR10509:SF14 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 methyltransferase#PC00155 HUMAN|HGNC=20318|UniProtKB=Q9H4F8 Q9H4F8 SMOC1 PTHR12352:SF13 SECRETED MODULAR CALCIUM-BINDING PROTEIN SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 1 heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;extracellular matrix binding#GO:0050840;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;basement membrane#GO:0005604;extracellular region#GO:0005576 calmodulin-related#PC00061 HUMAN|HGNC=6375|UniProtKB=P26717 P26717 KLRC2 PTHR22800:SF247 C-TYPE LECTIN PROTEINS NKG2-C TYPE II INTEGRAL MEMBRANE PROTEIN HUMAN|HGNC=6752|UniProtKB=P20645 P20645 M6PR PTHR15071:SF29 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-DEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=18674|UniProtKB=Q9UJV9 Q9UJV9 DDX41 PTHR47958:SF103 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX41-RELATED catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=18760|UniProtKB=Q9H6A9 Q9H6A9 PCNX3 PTHR12372:SF4 PECANEX PECANEX-LIKE PROTEIN 3 HUMAN|HGNC=26342|UniProtKB=Q96LM5 Q96LM5 C4orf45 PTHR34833:SF1 GENE, 17359-RELATED GENE, 17359-RELATED HUMAN|HGNC=3333|UniProtKB=P54849 P54849 EMP1 PTHR10671:SF6 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=43619|UniProtKB=A6NG13 A6NG13 MGAT4D PTHR12062:SF10 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN MGAT4D transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=4034|UniProtKB=P58549 P58549 FXYD7 PTHR14132:SF1 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 7 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of sodium ion transport#GO:0002028;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;sodium ion transport#GO:0006814;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;sodium ion transmembrane transport#GO:0035725 primary active transporter#PC00068 HUMAN|HGNC=7828|UniProtKB=Q86X76 Q86X76 NIT1 PTHR23088:SF27 NITRILASE-RELATED DEAMINATED GLUTATHIONE AMIDASE hydrolase#PC00121 HUMAN|HGNC=373|UniProtKB=O75969 O75969 AKAP3 PTHR10226:SF9 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN 3 protein kinase A binding#GO:0051018;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;macromolecule localization#GO:0033036;protein localization#GO:0008104 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;C2 axonemal microtubule#GO:1990720;B axonemal microtubule#GO:0097650;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;sperm principal piece#GO:0097228;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;axonemal microtubule#GO:0005879 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25154|UniProtKB=Q96EX1 Q96EX1 SMIM12 PTHR28599:SF2 SMALL INTEGRAL MEMBRANE PROTEIN 12 SMALL INTEGRAL MEMBRANE PROTEIN 12 HUMAN|HGNC=26198|UniProtKB=Q8WWC4 Q8WWC4 MAIP1 PTHR13333:SF5 M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205;protein localization to membrane#GO:0072657;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;peptide transport#GO:0015833;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=28993|UniProtKB=Q92508 Q92508 PIEZO1 PTHR13167:SF40 UNCHARACTERIZED PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;cellular response to stimulus#GO:0051716;response to mechanical stimulus#GO:0009612;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to environmental stimulus#GO:0104004 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=13348|UniProtKB=Q14210 Q14210 LY6D PTHR16982:SF2 LYMPHOCYTE ANTIGEN 6D LYMPHOCYTE ANTIGEN 6D HUMAN|HGNC=8923|UniProtKB=O43175 O43175 PHGDH PTHR42938:SF25 FORMATE DEHYDROGENASE 1 D-3-PHOSPHOGLYCERATE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid metabolic process#GO:0006520;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092 Serine glycine biosynthesis#P02776>Phosphoglycerate dehydrogenase#P03160 HUMAN|HGNC=16945|UniProtKB=Q9H074 Q9H074 PAIP1 PTHR23254:SF15 EIF4G DOMAIN PROTEIN POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;regulation of translational initiation#GO:0006446;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;translational initiation#GO:0006413;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 RNA metabolism protein#PC00031 HUMAN|HGNC=28913|UniProtKB=Q8IWL3 Q8IWL3 HSCB PTHR14021:SF15 IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB chaperone#PC00072 HUMAN|HGNC=25088|UniProtKB=Q5FBB7 Q5FBB7 SGO1 PTHR21577:SF3 SHUGOSHIN SHUGOSHIN 1 homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;meiotic sister chromatid segregation#GO:0045144;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;M phase#GO:0000279;sister chromatid cohesion#GO:0007062;chromosome organization involved in meiotic cell cycle#GO:0070192;mitotic cell cycle#GO:0000278;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;cell cycle phase#GO:0022403;meiosis I#GO:0007127;meiosis I cell cycle phase#GO:0098764;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;chromosome organization#GO:0051276;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;organelle fission#GO:0048285;biological phase#GO:0044848 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 centromere DNA-binding protein#PC00071 HUMAN|HGNC=14056|UniProtKB=Q5T653 Q5T653 MRPL2 PTHR13691:SF58 RIBOSOMAL PROTEIN L2 39S RIBOSOMAL PROTEIN L2, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=32429|UniProtKB=Q8N4L4 Q8N4L4 SPEM1 PTHR34834:SF1 SPERMATID MATURATION PROTEIN 1 SPERMATID MATURATION PROTEIN 1 male gamete generation#GO:0048232;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;microtubule-based movement#GO:0007018;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;cilium movement involved in cell motility#GO:0060294;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;spermatogenesis#GO:0007283;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;multicellular organism development#GO:0007275;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;multi-organism process#GO:0051704;cilium movement#GO:0003341;localization#GO:0051179;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;cilium-dependent cell motility#GO:0060285;reproduction#GO:0000003;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=8181|UniProtKB=Q8NGR6 Q8NGR6 OR1B1 PTHR48001:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1B1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=11573|UniProtKB=P17735 P17735 TAT PTHR45744:SF2 TYROSINE AMINOTRANSFERASE TYROSINE AMINOTRANSFERASE transaminase#PC00216 Tyrosine biosynthesis#P02784>Aromatic amino acid aminotransferase#P03213;Histidine biosynthesis#P02747>Histidinephosphate aminotransferase#P02991 HUMAN|HGNC=22202|UniProtKB=Q86XD5 Q86XD5 FAM131B PTHR15736:SF9 PROTEIN FAM131B-RELATED PROTEIN FAM131B HUMAN|HGNC=562|UniProtKB=O94973 O94973 AP2A2 PTHR22780:SF30 ADAPTIN, ALPHA/GAMMA/EPSILON AP-2 COMPLEX SUBUNIT ALPHA-2 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;plasma membrane region#GO:0098590;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Huntington disease#P00029>alpha-Adaptin#P00782 HUMAN|HGNC=21948|UniProtKB=Q6NUN9 Q6NUN9 ZNF746 PTHR24390:SF97 ZINC FINGER PROTEIN PROTEIN ZNF783-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13179|UniProtKB=Q9H2S9 Q9H2S9 IKZF4 PTHR24404:SF28 ZINC FINGER PROTEIN ZINC FINGER PROTEIN EOS cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29812|UniProtKB=Q96C86 Q96C86 DCPS PTHR12978:SF0 HISTIDINE TRIAD HIT PROTEIN MEMBER M7GPPPX DIPHOSPHATASE pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;RNA cap binding#GO:0000339 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;deadenylation-dependent decapping of nuclear-transcribed mRNA#GO:0000290;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 hydrolase#PC00121 HUMAN|HGNC=3782|UniProtKB=P49354 P49354 FNTA PTHR11129:SF5 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN FARNESYLTRANSFERASE/GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein prenylation#GO:0018342;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 acyltransferase#PC00042 HUMAN|HGNC=18598|UniProtKB=Q96CW5 Q96CW5 TUBGCP3 PTHR19302:SF14 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;reproductive process#GO:0022414;spindle assembly#GO:0051225;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cytoplasmic microtubule organization#GO:0031122;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;protein polymerization#GO:0051258;organelle fission#GO:0048285;cell cycle#GO:0007049 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;intracellular#GO:0005622;gamma-tubulin complex#GO:0000930;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=25904|UniProtKB=Q5T4D3 Q5T4D3 TMTC4 PTHR44227:SF3 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC4 HUMAN|HGNC=11128|UniProtKB=O95863 O95863 SNAI1 PTHR24390:SF92 ZINC FINGER PROTEIN ZINC FINGER PROTEIN SNAI1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 CCKR signaling map#P06959>SNAI1#P07055 HUMAN|HGNC=28670|UniProtKB=Q96C19 Q96C19 EFHD2 PTHR13025:SF2 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN D2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 calmodulin-related#PC00061 HUMAN|HGNC=18120|UniProtKB=Q9NSA0 Q9NSA0 SLC22A11 PTHR24064:SF241 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 11 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258 HUMAN|HGNC=12609|UniProtKB=P51784 P51784 USP11 PTHR21646:SF29 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 11 cysteine protease#PC00081 HUMAN|HGNC=1403|UniProtKB=P54284 P54284 CACNB3 PTHR11824:SF8 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-3 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;synaptic signaling#GO:0099536;divalent inorganic cation transport#GO:0072511;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;signaling#GO:0023052;cell-cell signaling#GO:0007267;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;regulation of calcium ion transport#GO:0051924;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;neuromuscular junction development#GO:0007528;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of ion transport#GO:0043269 membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411 HUMAN|HGNC=14375|UniProtKB=O75807 O75807 PPP1R15A PTHR16489:SF14 GH11727P PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15A hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;positive regulation of protein modification process#GO:0031401;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;regulation of phosphoprotein phosphatase activity#GO:0043666;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;regulation of phosphatase activity#GO:0010921;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=7758|UniProtKB=Q99519 Q99519 NEU1 PTHR10628:SF21 SIALIDASE SIALIDASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carbohydrate metabolic process#GO:0005975;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 hydrolase#PC00121 HUMAN|HGNC=20113|UniProtKB=Q6QHC5 Q6QHC5 DEGS2 PTHR12879:SF8 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE/C4-MONOOXYGENASE DES2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 hydroxylase#PC00122 HUMAN|HGNC=10379|UniProtKB=P09001 P09001 MRPL3 PTHR11229:SF13 50S RIBOSOMAL PROTEIN L3 39S RIBOSOMAL PROTEIN L3, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=5024|UniProtKB=P41235 P41235 HNF4A PTHR24083:SF41 NUCLEAR HORMONE RECEPTOR HEPATOCYTE NUCLEAR FACTOR 4-ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=10782|UniProtKB=Q05519 Q05519 SRSF11 PTHR32343:SF6 SERINE/ARGININE-RICH SPLICING FACTOR SERINE/ARGININE-RICH SPLICING FACTOR 11 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=19382|UniProtKB=O14508 O14508 SOCS2 PTHR10155:SF7 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phosphorylation#GO:0016310;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 HUMAN|HGNC=60|UniProtKB=O60706 O60706 ABCC9 PTHR24223:SF173 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=22222|UniProtKB=Q9C0H2 Q9C0H2 TTYH3 PTHR12424:SF4 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=11193|UniProtKB=O95416 O95416 SOX14 PTHR10270:SF107 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-14 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=21063|UniProtKB=Q6UVY6 Q6UVY6 MOXD1 PTHR10157:SF28 DOPAMINE BETA HYDROXYLASE RELATED DBH-LIKE MONOOXYGENASE PROTEIN 1 cation binding#GO:0043169;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 cellular aromatic compound metabolic process#GO:0006725;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;catecholamine metabolic process#GO:0006584;biosynthetic process#GO:0009058;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;aromatic compound catabolic process#GO:0019439;regulation of neurotransmitter levels#GO:0001505;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;extracellular region#GO:0005576;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 hydroxylase#PC00122 HUMAN|HGNC=10009|UniProtKB=Q02161 Q02161 RHD PTHR11730:SF43 AMMONIUM TRANSPORTER BLOOD GROUP RH(CE) POLYPEPTIDE-RELATED monovalent inorganic cation transmembrane transporter activity#GO:0015077;inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=12645|UniProtKB=O75379 O75379 VAMP4 PTHR46897:SF1 VESICLE-ASSOCIATED MEMBRANE PROTEIN 4 VESICLE-ASSOCIATED MEMBRANE PROTEIN 4 HUMAN|HGNC=27465|UniProtKB=Q8NDX6 Q8NDX6 ZNF740 PTHR24404:SF51 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 740 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=32950|UniProtKB=Q5VW00 Q5VW00 DCAF12L2 PTHR19860:SF8 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 12-LIKE PROTEIN 2 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 HUMAN|HGNC=29166|UniProtKB=P0C7N5 P0C7N5 OR8U9 PTHR48018:SF91 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=15740|UniProtKB=Q9UI42 Q9UI42 CPA4 PTHR11705:SF136 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A4 hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=3823|UniProtKB=Q9H334 Q9H334 FOXP1 PTHR45796:SF3 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18869|UniProtKB=Q86UU5 Q86UU5 GGN PTHR47742:SF1 GAMETOGENETIN GAMETOGENETIN enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 HUMAN|HGNC=18469|UniProtKB=Q9UIJ5 Q9UIJ5 ZDHHC2 PTHR22883:SF207 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;developmental process#GO:0032502;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;vesicle organization#GO:0016050;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;cellular process#GO:0009987;peptide transport#GO:0015833;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=20001|UniProtKB=Q8NBP7 Q8NBP7 PCSK9 PTHR43806:SF11 PEPTIDASE S8 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=2315|UniProtKB=Q96FN4 Q96FN4 CPNE2 PTHR10857:SF3 COPINE COPINE-2 calcium-dependent phospholipid binding#GO:0005544;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;binding#GO:0005488 response to metal ion#GO:0010038;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=35412|UniProtKB=Q6ZMW3 Q6ZMW3 EML6 PTHR13720:SF52 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 6 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 HUMAN|HGNC=12975|UniProtKB=Q99676 Q99676 ZNF184 PTHR24377:SF667 IP01015P-RELATED ZINC FINGER PROTEIN 184 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|Gene=DSA2D_HUMAN|UniProtKB=C9JQL5 C9JQL5 - PTHR13999:SF23 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN DISPANIN SUBFAMILY A MEMBER 2D-RELATED response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to cytokine#GO:0034097;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;innate immune response#GO:0045087;defense response to virus#GO:0051607;cytokine-mediated signaling pathway#GO:0019221;defense response#GO:0006952;signaling#GO:0023052;immune effector process#GO:0002252;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;cell communication#GO:0007154;cellular process#GO:0009987;response to type I interferon#GO:0034340;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;type I interferon signaling pathway#GO:0060337 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=9475|UniProtKB=P07477 P07477 PRSS1 PTHR24264:SF59 TRYPSIN-RELATED TRYPSIN-1 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=2303|UniProtKB=P16870 P16870 CPE PTHR11532:SF62 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE E hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190 CCKR signaling map#P06959>Carboxypeptidase E#P07026;Vasopressin synthesis#P04395>Exopeptidase#P04592 HUMAN|HGNC=16732|UniProtKB=Q96PE7 Q96PE7 MCEE PTHR43048:SF3 METHYLMALONYL-COA EPIMERASE METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL isomerase activity#GO:0016853;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 epimerase/racemase#PC00096 Methylmalonyl pathway#P02755>Methylmalonyl-CoA epimerase#P03032 HUMAN|HGNC=12988|UniProtKB=O14709 O14709 ZNF197 PTHR24376:SF212 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 197 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20256|UniProtKB=Q5VUG0 Q5VUG0 SFMBT2 PTHR12247:SF62 POLYCOMB GROUP PROTEIN SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 2 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=26257|UniProtKB=Q9H5P4 Q9H5P4 PDZD7 PTHR23116:SF29 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED PDZ DOMAIN-CONTAINING PROTEIN 7 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=24031|UniProtKB=Q9HBM1 Q9HBM1 SPC25 PTHR14281:SF0 KINETOCHORE PROTEIN SPC25-RELATED KINETOCHORE PROTEIN SPC25 cellular process#GO:0009987;chromosome segregation#GO:0007059 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular#GO:0005622;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;condensed chromosome, centromeric region#GO:0000779;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18474|UniProtKB=Q9ULC8 Q9ULC8 ZDHHC8 PTHR12349:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 PALMITOYLTRANSFERASE ZDHHC8 transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=894|UniProtKB=P01185 P01185 AVP PTHR11681:SF9 NEUROPHYSIN VASOPRESSIN-NEUROPHYSIN 2-COPEPTIN neuropeptide hormone activity#GO:0005184;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 neuropeptide#PC00162 Opioid prodynorphin pathway#P05916>provasopressin#P05999;Opioid prodynorphin pathway#P05916>prepropressophysin#G06050;Vasopressin synthesis#P04395>Pro-Vasopressin#P04598;Vasopressin synthesis#P04395>Signal Peptide#P04597;Opioid prodynorphin pathway#P05916>vasopressin#P06000;Vasopressin synthesis#P04395>Vasopressin#P04590;Opioid prodynorphin pathway#P05916>prepropressophysin#G06048;Vasopressin synthesis#P04395>Pro-Neurophysin#P04591;Vasopressin synthesis#P04395>Glycopeptide#P04593;Vasopressin synthesis#P04395>Pro2-Vasopressin#P04595;Vasopressin synthesis#P04395>Neurophysin#P04594 HUMAN|HGNC=18259|UniProtKB=Q8WWA0 Q8WWA0 ITLN1 PTHR16146:SF38 INTELECTIN INTELECTIN-1 HUMAN|Ensembl=ENSG00000283199|UniProtKB=A0A1B0GUA9 A0A1B0GUA9 C13orf46 PTHR39223:SF1 RIKEN CDNA 1700029H14 GENE RIKEN CDNA 1700029H14 GENE HUMAN|HGNC=25602|UniProtKB=Q86YJ6 Q86YJ6 THNSL2 PTHR42690:SF2 THREONINE SYNTHASE FAMILY MEMBER THREONINE SYNTHASE-LIKE 2 carbon-oxygen lyase activity#GO:0016835;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;aspartate family amino acid biosynthetic process#GO:0009067;small molecule catabolic process#GO:0044282;dephosphorylation#GO:0016311;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 Threonine biosynthesis#P02781>Threonine synthase#P03190 HUMAN|HGNC=10766|UniProtKB=Q15428 Q15428 SF3A2 PTHR23205:SF0 SPLICING FACTOR 3A SUBUNIT 2 SPLICING FACTOR 3A SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974 RNA splicing factor#PC00148 HUMAN|HGNC=1280|UniProtKB=P56557 P56557 TMEM50B PTHR13180:SF2 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50B endosomal transport#GO:0016197;establishment of protein localization to vacuole#GO:0072666;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;cellular protein localization#GO:0034613;vacuolar transport#GO:0007034;transport#GO:0006810;protein localization to vacuole#GO:0072665;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;late endosome to vacuole transport#GO:0045324;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 HUMAN|HGNC=24249|UniProtKB=Q9Y2Z4 Q9Y2Z4 YARS2 PTHR11766:SF0 TYROSYL-TRNA SYNTHETASE TYROSINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=7376|UniProtKB=P21757 P21757 MSR1 PTHR19331:SF440 SCAVENGER RECEPTOR DOMAIN-CONTAINING MACROPHAGE SCAVENGER RECEPTOR TYPES I AND II low-density lipoprotein particle binding#GO:0030169;amyloid-beta binding#GO:0001540;protein-containing complex binding#GO:0044877;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 response to external biotic stimulus#GO:0043207;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;regulation of localization#GO:0032879;detection of chemical stimulus#GO:0009593;regulation of biological process#GO:0050789;cellular component disassembly#GO:0022411;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle organization#GO:0016050;lipid localization#GO:0010876;receptor-mediated endocytosis#GO:0006898;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;response to organic substance#GO:0010033;plasma lipoprotein particle clearance#GO:0034381;protein-containing complex disassembly#GO:0032984;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;detection of stimulus#GO:0051606;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;vesicle budding from membrane#GO:0006900;response to chemical#GO:0042221;organelle organization#GO:0006996;maintenance of location#GO:0051235;response to other organism#GO:0051707;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;lipid storage#GO:0019915 serine protease#PC00203 HUMAN|HGNC=20264|UniProtKB=Q5BKY1 Q5BKY1 LRRC10 PTHR16083:SF8 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 10 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular developmental process#GO:0048869;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;cellular process#GO:0009987;tissue development#GO:0009888;cardiac muscle cell development#GO:0055013;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;cell development#GO:0048468;muscle structure development#GO:0061061;system development#GO:0048731;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;cardiocyte differentiation#GO:0035051;striated muscle cell development#GO:0055002;multicellular organismal process#GO:0032501 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229 HUMAN|HGNC=4882|UniProtKB=Q9NQ87 Q9NQ87 HEYL PTHR10985:SF79 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY/ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF-LIKE PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;Notch signaling pathway#GO:0007219 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 HUMAN|HGNC=14301|UniProtKB=Q702N8 Q702N8 XIRP1 PTHR22591:SF2 XIN XIN ACTIN-BINDING REPEAT-CONTAINING PROTEIN 1 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=34511|UniProtKB=Q6ZVS7 Q6ZVS7 FAM183BP PTHR33865:SF1 PROTEIN FAM183B PROTEIN FAM183BP ciliary transition fiber#GO:0097539;protein-containing complex#GO:0032991;ciliary base#GO:0097546;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 HUMAN|HGNC=11751|UniProtKB=Q14188 Q14188 TFDP2 PTHR12548:SF5 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP-2 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=19087|UniProtKB=Q9H4W6 Q9H4W6 EBF3 PTHR10747:SF4 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=32|UniProtKB=Q9BZC7 Q9BZC7 ABCA2 PTHR19229:SF225 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=1605|UniProtKB=P51679 P51679 CCR4 PTHR10489:SF608 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 4 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=5948|UniProtKB=Q8N6C5 Q8N6C5 IGSF1 PTHR11738:SF163 MHC CLASS I NK CELL RECEPTOR IMMUNOGLOBULIN SUPERFAMILY MEMBER 1 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=4849|UniProtKB=O43614 O43614 HCRTR2 PTHR24241:SF75 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OREXIN RECEPTOR TYPE 2 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=37218|UniProtKB=C9JDP6 C9JDP6 CLDN25 PTHR12002:SF87 CLAUDIN CLAUDIN-25-RELATED cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=14671|UniProtKB=Q9H9F9 Q9H9F9 ACTR5 PTHR11937:SF16 ACTIN ACTIN-RELATED PROTEIN 5 pyrophosphatase activity#GO:0016462;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of nucleic acid-templated transcription#GO:1903506;cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;Ino80 complex#GO:0031011;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 actin and actin related protein#PC00039 HUMAN|Ensembl=ENSG00000274042|UniProtKB=A0A0M3HER8 A0A0M3HER8 GOLGA6L10 PTHR23143:SF19 TRICHOHYALIN-RELATED GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 10-RELATED actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=26968|UniProtKB=Q96CX6 Q96CX6 LRRC58 PTHR45752:SF13 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 58 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|HGNC=1885|UniProtKB=P01215 P01215 CGA PTHR11509:SF0 GLYCOPROTEIN HORMONE ALPHA CHAIN GLYCOPROTEIN HORMONES ALPHA CHAIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;steroid metabolic process#GO:0008202;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;steroid biosynthetic process#GO:0006694;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585;Gonadotropin-releasing hormone receptor pathway#P06664>CGA#G06886;Gonadotropin-releasing hormone receptor pathway#P06664>CGA#G06673;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Thyrotropin#P04588;Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586 HUMAN|HGNC=7867|UniProtKB=P46087 P46087 NOP2 PTHR22807:SF30 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=10325|UniProtKB=P83731 P83731 RPL24 PTHR10792:SF44 60S RIBOSOMAL PROTEIN L24 60S RIBOSOMAL PROTEIN L24 structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=19036|UniProtKB=O60307 O60307 MAST3 PTHR24356:SF140 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE/THREONINE-PROTEIN KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=15859|UniProtKB=Q9H6P5 Q9H6P5 TASP1 PTHR10188:SF8 L-ASPARAGINASE THREONINE ASPARTASE 1 omega peptidase activity#GO:0008242;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;protein maturation#GO:0051604;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=20754|UniProtKB=Q9HCX4 Q9HCX4 TRPC7 PTHR10117:SF9 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 7 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 HUMAN|HGNC=29374|UniProtKB=Q76NI1 Q76NI1 KNDC1 PTHR21560:SF0 VERY KIND PROTEIN KINASE NON-CATALYTIC C-LOBE DOMAIN-CONTAINING PROTEIN 1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=19747|UniProtKB=Q86UK5 Q86UK5 EVC2 PTHR16795:SF14 LIMBIN/ELLIS-VAN CREVELD PROTEIN LIMBIN bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;ciliary membrane#GO:0060170;plasma membrane protein complex#GO:0098797;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=25208|UniProtKB=Q8WTR8 Q8WTR8 NTN5 PTHR10574:SF262 NETRIN/LAMININ-RELATED NETRIN-5 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;dendrite development#GO:0016358;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;motor neuron axon guidance#GO:0008045;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 HUMAN|HGNC=16470|UniProtKB=Q86VQ3 Q86VQ3 TXNDC2 PTHR10438:SF107 THIOREDOXIN THIOREDOXIN DOMAIN-CONTAINING PROTEIN 2 oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122 HUMAN|HGNC=8507|UniProtKB=Q99650 Q99650 OSMR PTHR23036:SF95 CYTOKINE RECEPTOR ONCOSTATIN-M-SPECIFIC RECEPTOR SUBUNIT BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=13076|UniProtKB=Q9UDV7 Q9UDV7 ZNF282 PTHR24381:SF276 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 282 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28528|UniProtKB=Q6UWM9 Q6UWM9 UGT2A3 PTHR48043:SF47 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2A3 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=26186|UniProtKB=Q6P2H8 Q6P2H8 TMEM53 PTHR12265:SF30 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 53 HUMAN|HGNC=10628|UniProtKB=P16619 P16619 CCL3L3 PTHR12015:SF151 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 3-LIKE 1 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=15529|UniProtKB=Q8NFZ3 Q8NFZ3 NLGN4Y PTHR43903:SF5 NEUROLIGIN NEUROLIGIN-4, Y-LINKED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;transport#GO:0006810;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;vesicle organization#GO:0016050;cell junction assembly#GO:0034329;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;endocytosis#GO:0006897;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;vesicle budding from membrane#GO:0006900;synapse assembly#GO:0007416;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;vesicle-mediated transport in synapse#GO:0099003 cell surface#GO:0009986;synapse#GO:0045202;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;cell junction#GO:0030054;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=10817|UniProtKB=O95470 O95470 SGPL1 PTHR42735:SF6 FAMILY NOT NAMED SPHINGOSINE-1-PHOSPHATE LYASE 1 HUMAN|HGNC=30093|UniProtKB=Q9UJX0 Q9UJX0 OSGIN1 PTHR15192:SF15 PROTEIN CBG05349 OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 1 HUMAN|HGNC=4626|UniProtKB=P08263 P08263 GSTA1 PTHR11571:SF157 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE A1 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;sulfur compound metabolic process#GO:0006790;cellular response to chemical stimulus#GO:0070887;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;response to stimulus#GO:0050896;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular#GO:0005622;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982 transferase#PC00220 HUMAN|HGNC=11979|UniProtKB=P50616 P50616 TOB1 PTHR17537:SF6 TRANSDUCER OF ERBB2 TOB PROTEIN TOB1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription corepressor activity#GO:0003714 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29600|UniProtKB=A0JLT2 A0JLT2 MED19 PTHR22536:SF1 LUNG CANCER METASTASIS-RELATED LCMR1 PROTEIN MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=33550|UniProtKB=Q68CJ6 Q68CJ6 NUGGC PTHR47308:SF1 NUCLEAR GTPASE SLIP-GC NUCLEAR GTPASE SLIP-GC GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 HUMAN|HGNC=17646|UniProtKB=Q96IV0 Q96IV0 NGLY1 PTHR12143:SF19 PEPTIDE N-GLYCANASE PNGASE -RELATED PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;carbohydrate derivative metabolic process#GO:1901135;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;macromolecule modification#GO:0043412;carbohydrate derivative catabolic process#GO:1901136;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;glycoprotein metabolic process#GO:0009100;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 hydrolase#PC00121 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 HUMAN|HGNC=3176|UniProtKB=P05305 P05305 EDN1 PTHR13874:SF10 ENDOTHELIN ENDOTHELIN-1 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 blood circulation#GO:0008015;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;system process#GO:0003008;positive regulation of molecular function#GO:0044093;regulation of blood vessel diameter#GO:0097746;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;oxidation-reduction process#GO:0055114;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;regulation of anatomical structure size#GO:0090066;cellular cation homeostasis#GO:0030003;positive regulation of catalytic activity#GO:0043085;smooth muscle contraction#GO:0006939;homeostatic process#GO:0042592;regulation of systemic arterial blood pressure#GO:0003073;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;circulatory system process#GO:0003013;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065;regulation of metabolic process#GO:0019222;muscle system process#GO:0003012;muscle contraction#GO:0006936 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Endothelin signaling pathway#P00019>ET1-4#P00588;Endothelin signaling pathway#P00019>Pro ET1-4#P00571;Endothelin signaling pathway#P00019>Big ET1-4#P00574;Endothelin signaling pathway#P00019>Pre-pro ET1-4#P00576 HUMAN|HGNC=20878|UniProtKB=Q9Y2A4 Q9Y2A4 ZNF443 PTHR24379:SF68 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 443 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7680|UniProtKB=P52848 P52848 NDST1 PTHR10605:SF30 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE/N-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;heparan sulfate proteoglycan metabolic process#GO:0030201;proteoglycan biosynthetic process#GO:0030166;cellular carbohydrate metabolic process#GO:0044262;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;cellular polysaccharide biosynthetic process#GO:0033692;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=365|UniProtKB=Q9Y6K8 Q9Y6K8 AK5 PTHR23359:SF79 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 5 nucleoside diphosphate kinase activity#GO:0004550;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;adenylate kinase activity#GO:0004017;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleoside diphosphate phosphorylation#GO:0006165;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 HUMAN|HGNC=16467|UniProtKB=Q15027 Q15027 ACAP1 PTHR23180:SF197 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=438|UniProtKB=P05186 P05186 ALPL PTHR11596:SF74 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 phosphatase#PC00181 HUMAN|HGNC=8862|UniProtKB=P10720 P10720 PF4V1 PTHR10179:SF38 CXC CHEMOKINE PLATELET FACTOR 4 VARIANT receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=13584|UniProtKB=Q9UKT4 Q9UKT4 FBXO5 PTHR15493:SF8 F-BOX ONLY PROTEIN 5 AND 43 F-BOX ONLY PROTEIN 5 regulation of mitotic nuclear division#GO:0007088;negative regulation of biological process#GO:0048519;nuclear division#GO:0000280;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;regulation of nuclear division#GO:0051783;negative regulation of cell cycle#GO:0045786;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;regulation of mitotic cell cycle#GO:0007346 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=31795|UniProtKB=A6PVI3 A6PVI3 NCBP2L PTHR18847:SF5 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2-LIKE nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152 protein-containing complex#GO:0032991;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=11397|UniProtKB=O00444 O00444 PLK4 PTHR24345:SF89 SERINE/THREONINE-PROTEIN KINASE PLK SERINE/THREONINE-PROTEIN KINASE PLK4 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=12629|UniProtKB=P35125 P35125 USP6 PTHR22957:SF617 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 6 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=17722|UniProtKB=Q7Z698 Q7Z698 SPRED2 PTHR11202:SF11 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 2 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of response to DNA damage stimulus#GO:2001020;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;cellular response to DNA damage stimulus#GO:0006974;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of response to DNA damage stimulus#GO:2001022;signal transduction by p53 class mediator#GO:0072331;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;signal transduction in response to DNA damage#GO:0042770;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of MAP kinase activity#GO:0043407;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;protein deacylation#GO:0035601;negative regulation of cellular protein metabolic process#GO:0032269;peptidyl-threonine phosphorylation#GO:0018107;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15576|UniProtKB=Q8WXR4 Q8WXR4 MYO3B PTHR46256:SF1 AGAP011099-PA MYOSIN-IIIB Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=29472|UniProtKB=A4D1U4 A4D1U4 DENND11 PTHR31017:SF2 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED DENN DOMAIN-CONTAINING PROTEIN 11 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=10799|UniProtKB=Q8IWL1 Q8IWL1 SFTPA2 PTHR24024:SF13 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A PULMONARY SURFACTANT-ASSOCIATED PROTEIN A1-RELATED endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;rough endoplasmic reticulum#GO:0005791;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;late endosome#GO:0005770;plasma membrane#GO:0005886 surfactant#PC00212 HUMAN|HGNC=24268|UniProtKB=Q8N9N2 Q8N9N2 ASCC1 PTHR13360:SF1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 HUMAN|HGNC=698|UniProtKB=P56559 P56559 ARL4C PTHR11711:SF119 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4C carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 HUMAN|HGNC=24722|UniProtKB=Q8N883 Q8N883 ZNF614 PTHR24381:SF110 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 614 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9774|UniProtKB=Q15286 Q15286 RAB35 PTHR47977:SF26 LD21953P-RELATED RAS-RELATED PROTEIN RAB-35 HUMAN|HGNC=14283|UniProtKB=Q9H5V7 Q9H5V7 IKZF5 PTHR24404:SF55 ZINC FINGER PROTEIN ZINC FINGER PROTEIN PEGASUS cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20944|UniProtKB=Q9GZR1 Q9GZR1 SENP6 PTHR46896:SF1 SENTRIN-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 6 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein-specific protease activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;kinetochore organization#GO:0051383;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;peptidyl-amino acid modification#GO:0018193;protein-DNA complex assembly#GO:0065004;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule cytoskeleton organization#GO:0070507;proteolysis#GO:0006508;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;kinetochore assembly#GO:0051382;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular protein modification process#GO:0006464;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=2479|UniProtKB=O76096 O76096 CST7 PTHR47141:SF1 CYSTATIN-F CYSTATIN-F cysteine-type peptidase activity#GO:0008234;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;peptidase activity#GO:0008233;endopeptidase regulator activity#GO:0061135;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;system process#GO:0003008;gene expression#GO:0010467;negative regulation of inflammatory response#GO:0050728;nervous system development#GO:0007399;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;negative regulation of endopeptidase activity#GO:0010951;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of leukocyte activation#GO:0002695;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of defense response#GO:0031347;multicellular organismal process#GO:0032501;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;myelination#GO:0042552;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of system process#GO:0044057;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;protein processing#GO:0016485;inflammatory response#GO:0006954;system development#GO:0048731;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of peptidase activity#GO:0010466;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;nervous system process#GO:0050877;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;negative regulation of cell activation#GO:0050866;regulation of primary metabolic process#GO:0080090;regulation of inflammatory response#GO:0050727;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;negative regulation of cellular protein metabolic process#GO:0032269;regulation of leukocyte activation#GO:0002694;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;negative regulation of immune system process#GO:0002683;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=20679|UniProtKB=A1A5B4 A1A5B4 ANO9 PTHR12308:SF37 NGEP-RELATED ANOCTAMIN-9 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;inorganic anion transport#GO:0015698;anion transmembrane transport#GO:0098656 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=37278|UniProtKB=B0FP48 B0FP48 UPK3BL1 PTHR15446:SF2 UROPLAKIN III UROPLAKIN-3B-LIKE PROTEIN 1-RELATED intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=25312|UniProtKB=Q6UWH4 Q6UWH4 GASK1B PTHR15905:SF1 GOLGI-ASSOCIATED KINASE 1B-RELATED GOLGI-ASSOCIATED KINASE 1B HUMAN|HGNC=11821|UniProtKB=P16035 P16035 TIMP2 PTHR11844:SF24 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 2 metalloendopeptidase activity#GO:0004222;peptidase inhibitor activity#GO:0030414;metallopeptidase activity#GO:0008237;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of catabolic process#GO:0009895;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=5362|UniProtKB=Q02535 Q02535 ID3 PTHR11723:SF16 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-3 molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Id3#P06711 HUMAN|HGNC=24321|UniProtKB=Q7Z401 Q7Z401 DENND4A PTHR12296:SF16 C-MYC PROMOTER BINDING PROTEIN C-MYC PROMOTER-BINDING PROTEIN Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;regulation of Ras protein signal transduction#GO:0046578;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=26208|UniProtKB=Q9H649 Q9H649 NSUN3 PTHR22808:SF8 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(34)-C(5))-METHYLTRANSFERASE, MITOCHONDRIAL methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;RNA methylation#GO:0001510 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 RNA methyltransferase#PC00033 HUMAN|HGNC=18884|UniProtKB=Q9NUW8 Q9NUW8 TDP1 PTHR12415:SF0 TYROSYL-DNA PHOSPHODIESTERASE 1 TYROSYL-DNA PHOSPHODIESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 phosphodiesterase#PC00185 HUMAN|HGNC=5134|UniProtKB=P31277 P31277 HOXD11 PTHR46092:SF2 HOMEOBOX PROTEIN HOX-A11-RELATED HOMEOBOX PROTEIN HOX-D11 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=35410|UniProtKB=Q8NFU3 Q8NFU3 TSTD1 PTHR45544:SF1 THIOSULFATE:GLUTATHIONE SULFURTRANSFERASE THIOSULFATE:GLUTATHIONE SULFURTRANSFERASE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transferase#PC00220 HUMAN|HGNC=21607|UniProtKB=Q9NVV5 Q9NVV5 AIG1 PTHR10989:SF11 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN-INDUCED GENE 1 PROTEIN cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=19383|UniProtKB=O15524 O15524 SOCS1 PTHR10155:SF4 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phosphorylation#GO:0016310;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 JAK/STAT signaling pathway#P00038>SOCS#P01030 HUMAN|HGNC=44206|UniProtKB=A6NC86 A6NC86 PINLYP PTHR20914:SF23 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 8 PHOSPHOLIPASE A2 INHIBITOR AND LY6/PLAUR DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=8789|UniProtKB=P18545 P18545 PDE6G PTHR12122:SF4 RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 bounding membrane of organelle#GO:0098588;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 phosphodiesterase#PC00185 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEgamma#P00754 HUMAN|HGNC=17772|UniProtKB=Q99757 Q99757 TXN2 PTHR43601:SF3 THIOREDOXIN, MITOCHONDRIAL THIOREDOXIN, MITOCHONDRIAL oxidoreductase#PC00176 Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 HUMAN|HGNC=16412|UniProtKB=Q9NPP4 Q9NPP4 NLRC4 PTHR47688:SF1 NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;detection of stimulus#GO:0051606;defense response#GO:0006952 HUMAN|HGNC=24699|UniProtKB=Q8TEJ3 Q8TEJ3 SH3RF3 PTHR14167:SF62 SH3 DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE SH3RF3 HUMAN|HGNC=6983|UniProtKB=P48163 P48163 ME1 PTHR23406:SF17 MALIC ENZYME-RELATED NADP-DEPENDENT MALIC ENZYME catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176 Pyruvate metabolism#P02772>Malic enzyme#P03136 HUMAN|HGNC=32151|UniProtKB=Q5T2N8 Q5T2N8 ATAD3C PTHR23075:SF4 PUTATIVE ATP-ASE ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3C cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9248|UniProtKB=O75335 O75335 PPFIA4 PTHR12587:SF5 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-4 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 HUMAN|HGNC=28395|UniProtKB=Q8NHU3 Q8NHU3 SGMS2 PTHR21290:SF24 SPHINGOMYELIN SYNTHETASE PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;phosphate-containing compound metabolic process#GO:0006796;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;intrinsic component of plasma membrane#GO:0031226;Golgi membrane#GO:0000139;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=25628|UniProtKB=Q9NUU7 Q9NUU7 DDX19A PTHR47958:SF131 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX19A catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;ribonucleoprotein complex localization#GO:0071166;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|Ensembl=ENSG00000216921|UniProtKB=A0A1B0GVR7 A0A1B0GVR7 FAM240C PTHR40387:SF4 PROTEIN FAM240B PROTEIN FAM240C HUMAN|HGNC=7706|UniProtKB=O95298 O95298 NDUFC2 PTHR13099:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B14.5B NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C2-RELATED envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=19133|UniProtKB=Q96MM7 Q96MM7 HS6ST2 PTHR12812:SF6 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;heparan sulfate proteoglycan metabolic process#GO:0030201;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=8975|UniProtKB=P42336 P42336 PIK3CA PTHR10048:SF107 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;phosphatidylinositol-mediated signaling#GO:0048015;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;phosphatidylinositol 3-kinase signaling#GO:0014065;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;inositol lipid-mediated signaling#GO:0048017;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477;locomotion#GO:0040011;phosphatidylinositol phosphorylation#GO:0046854 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;p53 pathway feedback loops 2#P04398>P110ALPHA#G04707;PI3 kinase pathway#P00048>p110#P01192;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;p53 pathway#P00059>P110alpha#P04633;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway feedback loops 2#P04398>P110alpha#P04657;p53 pathway#P00059>p110alpha#G04694;Endothelin signaling pathway#P00019>PI3K#P00577;Integrin signalling pathway#P00034>PI3K#P00936;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>P110alpha#P04498;Angiogenesis#P00005>PI3K#P00236;B cell activation#P00010>PI3K#P00391;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;p53 pathway#P00059>PI3K#P04609;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>p110alpha#G04676;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Interleukin signaling pathway#P00036>PI3K#P00990;PI3 kinase pathway#P00048>P110ACT#P01177 HUMAN|HGNC=25853|UniProtKB=Q86WT1 Q86WT1 TTC30A PTHR20931:SF3 UNCHARACTERIZED TETRATRICOPEPTIDE REPEAT PROTEIN 30A protein-containing complex binding#GO:0044877;binding#GO:0005488 microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;cytoskeleton#GO:0005856;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 HUMAN|HGNC=33829|UniProtKB=Q6ZR37 Q6ZR37 PLEKHG7 PTHR13217:SF6 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 HUMAN|HGNC=13939|UniProtKB=Q9Y334 Q9Y334 VWA7 PTHR14905:SF7 NG37 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 7 HUMAN|HGNC=16997|UniProtKB=Q13015 Q13015 MLLT11 PTHR15404:SF2 PROTEIN AF1Q PROTEIN AF1Q positive regulation of gene expression#GO:0010628;apoptotic mitochondrial changes#GO:0008637;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;regulation of apoptotic signaling pathway#GO:2001233;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of mitochondrion organization#GO:0010821;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of organelle organization#GO:0010638;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;positive regulation of programmed cell death#GO:0043068;ion homeostasis#GO:0050801;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;cell death#GO:0008219;positive regulation of apoptotic signaling pathway#GO:2001235;mitochondrion organization#GO:0007005;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;nucleic acid-templated transcription#GO:0097659;positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;regulation of membrane potential#GO:0042391;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;chemical homeostasis#GO:0048878;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of cellular component organization#GO:0051130;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;positive regulation of cell death#GO:0010942;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18268|UniProtKB=Q6UX01 Q6UX01 LMBR1L PTHR12625:SF2 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR PROTEIN LMBR1L signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=14767|UniProtKB=Q8NGV6 Q8NGV6 OR5H6 PTHR26452:SF754 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5H6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=4658|UniProtKB=Q92759 Q92759 GTF2H4 PTHR13152:SF0 TFIIH, POLYPEPTIDE 4 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 4 heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;nucleotide-excision repair#GO:0006289;phosphorylation of RNA polymerase II C-terminal domain#GO:0070816;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 HUMAN|HGNC=19706|UniProtKB=Q6UY14 Q6UY14 ADAMTSL4 PTHR13723:SF144 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 4 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=26572|UniProtKB=Q6P5X7 Q6P5X7 TMEM71 PTHR35255:SF1 TRANSMEMBRANE PROTEIN 71 TRANSMEMBRANE PROTEIN 71 HUMAN|HGNC=29442|UniProtKB=O75037 O75037 KIF21B PTHR24115:SF893 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF21B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=20750|UniProtKB=Q8IVQ6 Q8IVQ6 ZDHHC21 PTHR22883:SF11 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC21 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=2198|UniProtKB=P08123 P08123 COL1A2 PTHR24023:SF568 COLLAGEN ALPHA COLLAGEN ALPHA-2(I) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;extracellular region#GO:0005576;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|Ensembl=ENSG00000284476|UniProtKB=A0A1W2PRE2 A0A1W2PRE2 ENSG00000284476 PTHR11667:SF27 FAMILY NOT NAMED SUBFAMILY NOT NAMED HUMAN|HGNC=9240|UniProtKB=P02775 P02775 PPBP PTHR10179:SF52 CXC CHEMOKINE PLATELET BASIC PROTEIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=20964|UniProtKB=A6NIX2 A6NIX2 WTIP PTHR24219:SF6 LIM DOMAIN-CONTAINING PROTEIN JUB WILMS TUMOR PROTEIN 1-INTERACTING PROTEIN molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;post-transcriptional gene silencing by RNA#GO:0035194;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;response to decreased oxygen levels#GO:0036293;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;posttranscriptional gene silencing#GO:0016441;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to hypoxia#GO:0001666;RNA metabolic process#GO:0016070;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;response to oxygen levels#GO:0070482;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;gene silencing by miRNA#GO:0035195;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;gene silencing by RNA#GO:0031047;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;hippo signaling#GO:0035329;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 supramolecular complex#GO:0099080;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912 transcription cofactor#PC00217 HUMAN|HGNC=3539|UniProtKB=O00254 O00254 F2RL2 PTHR24232:SF0 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Blood coagulation#P00011>mPAR-3#P00452 HUMAN|HGNC=29836|UniProtKB=Q9NRX3 Q9NRX3 NDUFA4L2 PTHR14256:SF5 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 4-LIKE 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277 oxidoreductase#PC00176 HUMAN|HGNC=16941|UniProtKB=O76038 O76038 SCGN PTHR19972:SF15 CALBINDIN SECRETAGOGIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of signaling#GO:0023051;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;synaptic signaling#GO:0099536;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;anatomical structure homeostasis#GO:0060249;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular cation homeostasis#GO:0030003;trans-synaptic signaling#GO:0099537;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular ion homeostasis#GO:0006873;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;cellular chemical homeostasis#GO:0055082;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;metal ion homeostasis#GO:0055065 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;terminal bouton#GO:0043195;dendrite#GO:0030425;cytosol#GO:0005829;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane#GO:0005886 calmodulin-related#PC00061 HUMAN|HGNC=31266|UniProtKB=Q6IF82 Q6IF82 OR4A47 PTHR48002:SF102 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4A47 transmembrane signal receptor#PC00197 HUMAN|HGNC=6077|UniProtKB=P32019 P32019 INPP5B PTHR11200:SF163 INOSITOL 5-PHOSPHATASE TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;small molecule catabolic process#GO:0044282;glycerolipid metabolic process#GO:0046486;cellular carbohydrate metabolic process#GO:0044262;dephosphorylation#GO:0016311;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=3515|UniProtKB=Q92935 Q92935 EXTL1 PTHR11062:SF8 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 1 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=12617|UniProtKB=O94966 O94966 USP19 PTHR21646:SF74 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 19 cysteine protease#PC00081 HUMAN|HGNC=83|UniProtKB=P42765 P42765 ACAA2 PTHR18919:SF145 ACETYL-COA C-ACYLTRANSFERASE 3-KETOACYL-COA THIOLASE, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=15770|UniProtKB=Q12836 Q12836 ZP4 PTHR23343:SF31 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 4 HUMAN|HGNC=31853|UniProtKB=Q6DHV7 Q6DHV7 ADAL PTHR11409:SF42 ADENOSINE DEAMINASE ADENOSINE DEAMINASE-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine-containing compound metabolic process#GO:0072521;pigment biosynthetic process#GO:0046148;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase biosynthetic process#GO:0009113;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 deaminase#PC00088 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 HUMAN|HGNC=3015|UniProtKB=Q14195 Q14195 DPYSL3 PTHR11647:SF57 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 3 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;actin filament-based process#GO:0030029;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;catabolic process#GO:0009056;cytoskeleton organization#GO:0007010;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;actin cytoskeleton organization#GO:0030036;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 HUMAN|HGNC=638|UniProtKB=P55064 P55064 AQP5 PTHR19139:SF38 AQUAPORIN TRANSPORTER AQUAPORIN-5 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 intrinsic component of membrane#GO:0031224;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177 transporter#PC00227 HUMAN|HGNC=6631|UniProtKB=P49257 P49257 LMAN1 PTHR12223:SF32 VESICULAR MANNOSE-BINDING LECTIN PROTEIN ERGIC-53 carbohydrate binding#GO:0030246;small molecule binding#GO:0036094;binding#GO:0005488 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;Golgi organization#GO:0007030;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 HUMAN|HGNC=21207|UniProtKB=Q7L985 Q7L985 LINGO2 PTHR24373:SF38 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 2 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=26078|UniProtKB=Q8N0Z9 Q8N0Z9 VSIG10 PTHR11640:SF140 NEPHRIN V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=12545|UniProtKB=O75310 O75310 UGT2B11 PTHR48043:SF86 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2B10-RELATED transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=21338|UniProtKB=Q99811 Q99811 PRRX2 PTHR46385:SF3 PAIRED MESODERM HOMEOBOX PROTEIN 1-RELATED PAIRED MESODERM HOMEOBOX PROTEIN 2 Gonadotropin-releasing hormone receptor pathway#P06664>Prx2#P06731 HUMAN|HGNC=25930|UniProtKB=Q8NAV1 Q8NAV1 PRPF38A PTHR23142:SF7 UNCHARACTERIZED PRE-MRNA-SPLICING FACTOR 38A ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=31851|UniProtKB=A0A0U1RR11 A0A0U1RR11 CENPVL1 PTHR28620:SF3 CENTROMERE PROTEIN V CENTROMERE PROTEIN V-LIKE PROTEIN 1 HUMAN|HGNC=29071|UniProtKB=A3KMH1 A3KMH1 VWA8 PTHR21610:SF9 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=7819|UniProtKB=P55769 P55769 SNU13 PTHR23105:SF38 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER NHP2-LIKE PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=16716|UniProtKB=Q7L2E3 Q7L2E3 DHX30 PTHR18934:SF237 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX30 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA helicase#PC00032 HUMAN|HGNC=4739|UniProtKB=P16104 P16104 H2AX PTHR23430:SF199 HISTONE H2A HISTONE H2AX heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=22411|UniProtKB=Q8N7C7 Q8N7C7 RNF148 PTHR22765:SF53 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING FINGER PROTEIN 148 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=39035|UniProtKB=P61565 P61565 ERVK-21 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED viral or transposable element protein#PC00237 HUMAN|HGNC=40024|UniProtKB=E9PGG2 E9PGG2 ANHX PTHR10390:SF34 HOMEOBOX PROTEIN SIX ANOMALOUS HOMEOBOX PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;brain development#GO:0007420;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;sensory system development#GO:0048880;visual system development#GO:0150063;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;eye development#GO:0001654;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;sensory organ development#GO:0007423;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 HUMAN|HGNC=2715|UniProtKB=O94760 O94760 DDAH1 PTHR12737:SF17 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE N(G),N(G)-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1 amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;regulation of reactive oxygen species metabolic process#GO:2000377;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of cellular biosynthetic process#GO:0031326;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323 hydrolase#PC00121 HUMAN|HGNC=958|UniProtKB=Q16520 Q16520 BATF PTHR23351:SF14 FOS TRANSCRIPTION FACTOR-RELATED BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302 HUMAN|HGNC=18502|UniProtKB=Q9BQ87 Q9BQ87 TBL1Y PTHR22846:SF64 WD40 REPEAT PROTEIN F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1Y molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;protein deacetylation#GO:0006476;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Wnt signaling pathway#P00057>Ebi#P01453 HUMAN|HGNC=648|UniProtKB=Q7LC44 Q7LC44 ARC PTHR15962:SF0 ACTIVITY-REGULATED CYTOSKELETON-ASSOCIATED PROTEIN ACTIVITY-REGULATED CYTOSKELETON-ASSOCIATED PROTEIN HUMAN|HGNC=37646|UniProtKB=D3W0D1 D3W0D1 KLRF2 PTHR46746:SF6 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY F MEMBER 2 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY F MEMBER 2 transmembrane signal receptor#PC00197 HUMAN|HGNC=33463|UniProtKB=Q3ZCQ2 Q3ZCQ2 ANXA2R PTHR38820:SF1 ANNEXIN-2 RECEPTOR ANNEXIN-2 RECEPTOR transmembrane signal receptor#PC00197 HUMAN|HGNC=30171|UniProtKB=Q9UJY1 Q9UJY1 HSPB8 PTHR46906:SF1 HEAT SHOCK PROTEIN BETA-8 HEAT SHOCK PROTEIN BETA-8 response to organic substance#GO:0010033;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to organic substance#GO:0071310;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;response to unfolded protein#GO:0006986;cellular process#GO:0009987;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967 cytoplasm#GO:0005737;chaperone complex#GO:0101031;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3629|UniProtKB=P37268 P37268 FDFT1 PTHR11626:SF2 FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE SQUALENE SYNTHASE prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 Cholesterol biosynthesis#P00014>Farnesyl-diphosphate farnesyltransferase#P00499 HUMAN|HGNC=6847|UniProtKB=O14733 O14733 MAP2K7 PTHR48013:SF17 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>MKK7#P00312;Ras Pathway#P04393>MKK4/7#P04565;Huntington disease#P00029>MAPKK7#P00784;Gonadotropin-releasing hormone receptor pathway#P06664>MKK4/7#P06760;FGF signaling pathway#P00021>MKK4,7#P00637;EGF receptor signaling pathway#P00018>MKK4,7#P00555 HUMAN|HGNC=25222|UniProtKB=Q96DZ1 Q96DZ1 ERLEC1 PTHR15414:SF0 OS-9-RELATED ENDOPLASMIC RETICULUM LECTIN 1 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;modification-dependent macromolecule catabolic process#GO:0043632;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;ubiquitin-dependent ERAD pathway#GO:0030433;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=18683|UniProtKB=P38919 P38919 EIF4A3 PTHR47958:SF49 ATP-DEPENDENT RNA HELICASE DBP3 EUKARYOTIC INITIATION FACTOR 4A-III catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 membrane-enclosed lumen#GO:0031974;catalytic step 2 spliceosome#GO:0071013;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974 HUMAN|HGNC=26850|UniProtKB=Q8N801 Q8N801 STPG4 PTHR35678:SF1 PROTEIN STPG4 PROTEIN STPG4 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;demethylation#GO:0070988;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=22205|UniProtKB=Q2PZI1 Q2PZI1 DPY19L1 PTHR31488:SF5 DPY-19-LIKE 1, LIKE (H. SAPIENS) C-MANNOSYLTRANSFERASE DPY19L1-RELATED transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=24473|UniProtKB=Q6UWY5 Q6UWY5 OLFML1 PTHR23192:SF13 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 1 structural protein#PC00211 HUMAN|HGNC=12226|UniProtKB=A0A0K0K1D8 A0A0K0K1D8 TRBV6-1 PTHR23268:SF107 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 6-1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=4014|UniProtKB=P21217 P21217 FUT3 PTHR11929:SF165 ALPHA- 1,3 -FUCOSYLTRANSFERASE 3-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 4-ALPHA-L-FUCOSYLTRANSFERASE FUT3 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111 HUMAN|HGNC=26697|UniProtKB=Q8N9V3 Q8N9V3 WDSUB1 PTHR46573:SF1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=1717|UniProtKB=Q16181 Q16181 SEPTIN7 PTHR18884:SF129 SEPTIN SEPTIN-7 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;cell division#GO:0051301;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;cytokinesis#GO:0000910;membrane fission#GO:0090148;vesicle localization#GO:0051648;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;cell cycle#GO:0007049 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 HUMAN|HGNC=9008|UniProtKB=P98161 P98161 PKD1 PTHR46730:SF1 POLYCYSTIN-1 POLYCYSTIN-1 HUMAN|HGNC=24248|UniProtKB=Q8N6R0 Q8N6R0 EEF1AKNMT PTHR12176:SF75 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE AND N-TERMINAL METHYLTRANSFERASE methyltransferase#PC00155 HUMAN|HGNC=3537|UniProtKB=P25116 P25116 F2R PTHR24232:SF20 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 1 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;regulation of coagulation#GO:0050818;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;regulation of wound healing#GO:0061041;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of multicellular organismal process#GO:0051239;regulation of phospholipase C activity#GO:1900274;regulation of body fluid levels#GO:0050878;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;response to stress#GO:0006950;response to wounding#GO:0009611;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of multicellular organismal process#GO:0051240;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;wound healing#GO:0042060;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of wound healing#GO:0090303;regulation of response to external stimulus#GO:0032101;positive regulation of catalytic activity#GO:0043085;regulation of response to stress#GO:0080134;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;hemostasis#GO:0007599;Rho protein signal transduction#GO:0007266;coagulation#GO:0050817;regulation of response to wounding#GO:1903034;cellular chemical homeostasis#GO:0055082;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;biological regulation#GO:0065007;blood coagulation#GO:0007596 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Blood coagulation#P00011>PAR-1#P00404;Angiogenesis#P00005>PAR#P00192 HUMAN|HGNC=4680|UniProtKB=O95843 O95843 GUCA1C PTHR23055:SF80 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 3 HUMAN|HGNC=19683|UniProtKB=Q8TAS1 Q8TAS1 UHMK1 PTHR46962:SF1 SERINE/THREONINE-PROTEIN KINASE KIST SERINE/THREONINE-PROTEIN KINASE KIST transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoprotein complex binding#GO:0043021;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;cellular localization#GO:0051641;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of translational initiation#GO:0045948;positive regulation of cellular metabolic process#GO:0031325;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of translational initiation#GO:0006446;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;nuclear transport#GO:0051169;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cellular localization#GO:0060341;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;cell cycle arrest#GO:0007050;peptide biosynthetic process#GO:0043043;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;regulation of cellular process#GO:0050794;protein transport#GO:0015031;regulation of translation#GO:0006417;intracellular transport#GO:0046907;translational elongation#GO:0006414;regulation of establishment of protein localization#GO:0070201;regulation of metabolic process#GO:0019222;regulation of peptide transport#GO:0090087;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;peptide metabolic process#GO:0006518;cellular protein localization#GO:0034613;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;cell cycle process#GO:0022402;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;translation#GO:0006412;amide transport#GO:0042886;positive regulation of biosynthetic process#GO:0009891;organic substance transport#GO:0071702;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;protein export from nucleus#GO:0006611;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;regulation of protein transport#GO:0051223;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nucleocytoplasmic transport#GO:0006913;biological regulation#GO:0065007;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;peptidyl-serine modification#GO:0018209;establishment of localization in cell#GO:0051649;translational initiation#GO:0006413;regulation of cell cycle#GO:0051726;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=16879|UniProtKB=O95072 O95072 REC8 PTHR12585:SF27 SCC1 / RAD21 FAMILY MEMBER MEIOTIC RECOMBINATION PROTEIN REC8 HOMOLOG chromatin binding#GO:0003682;binding#GO:0005488 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;double-strand break repair#GO:0006302;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;meiotic sister chromatid segregation#GO:0045144;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;M phase#GO:0000279;sister chromatid cohesion#GO:0007062;chromosome organization involved in meiotic cell cycle#GO:0070192;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;meiosis I cell cycle phase#GO:0098764;cellular response to stimulus#GO:0051716;mitotic sister chromatid cohesion#GO:0007064;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=30491|UniProtKB=Q69YW2 Q69YW2 STUM PTHR21676:SF1 UNCHARACTERIZED PROTEIN STUM HOMOLOG HUMAN|HGNC=3595|UniProtKB=Q14517 Q14517 FAT1 PTHR24026:SF42 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN FAT 1 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=1768|UniProtKB=Q9ULB4 Q9ULB4 CDH9 PTHR24027:SF99 CADHERIN-23 CADHERIN-9 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=30633|UniProtKB=Q96IW2 Q96IW2 SHD PTHR15127:SF33 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN D protein binding#GO:0005515;binding#GO:0005488 HUMAN|HGNC=14548|UniProtKB=Q96TA0 Q96TA0 PCDHB18P PTHR24028:SF98 CADHERIN-87A PROTOCADHERIN BETA-18-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=21748|UniProtKB=Q6X4U4 Q6X4U4 SOSTDC1 PTHR14903:SF5 SCLEROSTIN-RELATED SCLEROSTIN DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;negative regulation of cellular response to growth factor stimulus#GO:0090288;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;Wnt signaling pathway#GO:0016055;response to organic substance#GO:0010033;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=23039|UniProtKB=O94874 O94874 UFL1 PTHR31057:SF0 E3 UFM1-PROTEIN LIGASE 1 E3 UFM1-PROTEIN LIGASE 1 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;regulation of cellular protein catabolic process#GO:1903362;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=3153|UniProtKB=Q16610 Q16610 ECM1 PTHR16776:SF3 EXTRACELLULAR MATRIX PROTEIN 1 EXTRACELLULAR MATRIX PROTEIN 1 biomineralization#GO:0110148;regulation of multicellular organismal process#GO:0051239;ossification#GO:0001503;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of multicellular organismal development#GO:2000026;tissue development#GO:0009888;bone mineralization#GO:0030282;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;biomineral tissue development#GO:0031214;regulation of ossification#GO:0030278 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=11853|UniProtKB=P30408 P30408 TM4SF1 PTHR14198:SF18 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 1 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=13175|UniProtKB=A8MXY4 A8MXY4 ZNF99 PTHR24376:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 208-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=17976|UniProtKB=Q96L21 Q96L21 RPL10L PTHR11726:SF29 60S RIBOSOMAL PROTEIN L10 60S RIBOSOMAL PROTEIN L10-LIKE structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=22402|UniProtKB=Q8TBZ9 Q8TBZ9 TEX47 PTHR34035:SF1 TESTIS-EXPRESSED PROTEIN 47 TESTIS-EXPRESSED PROTEIN 47 HUMAN|HGNC=44209|UniProtKB=E7EU14 E7EU14 PPP5D1 PTHR12138:SF121 PRIMATE-EXPANDED PROTEIN FAMILY PROTEIN PPP5D1 HUMAN|HGNC=9761|UniProtKB=Q15907 Q15907 RAB11B PTHR47979:SF41 DRAB11-RELATED RAS-RELATED PROTEIN RAB-11B vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;regulated exocytosis#GO:0045055;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 PDGF signaling pathway#P00047>Ras#P01154 HUMAN|HGNC=28861|UniProtKB=P57730 P57730 CARD18 PTHR47901:SF3 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 enzyme binding#GO:0019899;protein binding#GO:0005515;protease binding#GO:0002020;binding#GO:0005488 HUMAN|HGNC=575|UniProtKB=Q9Y587 Q9Y587 AP4S1 PTHR11753:SF57 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-4 COMPLEX SUBUNIT SIGMA-1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 HUMAN|HGNC=12758|UniProtKB=Q9NNW5 Q9NNW5 WDR6 PTHR14344:SF3 WD REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 6 HUMAN|Ensembl=ENSG00000285566|UniProtKB=A0A3B3IRS2 A0A3B3IRS2 LOC647264 PTHR31294:SF17 FAMILY NOT NAMED KERATIN-ASSOCIATED PROTEIN 21-1 HUMAN|HGNC=28196|UniProtKB=Q9BSE2 Q9BSE2 TMEM79 PTHR31004:SF1 TRANSMEMBRANE PROTEIN 79 TRANSMEMBRANE PROTEIN 79 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;regulated exocytosis#GO:0045055;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=11872|UniProtKB=Q9NZR1 Q9NZR1 TMOD2 PTHR10901:SF15 TROPOMODULIN TROPOMODULIN-2 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=15104|UniProtKB=Q8NGT0 Q8NGT0 OR13C9 PTHR26453:SF315 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C9 transmembrane signal receptor#PC00197 HUMAN|HGNC=20184|UniProtKB=Q9P055 Q9P055 JKAMP PTHR12740:SF4 JNK1/MAPK8-ASSOCIATED MEMBRANE PROTEIN JNK1/MAPK8-ASSOCIATED MEMBRANE PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 scaffold/adaptor protein#PC00226 HUMAN|HGNC=4563|UniProtKB=O75791 O75791 GRAP2 PTHR46037:SF3 PROTEIN ENHANCER OF SEVENLESS 2B GRB2-RELATED ADAPTER PROTEIN 2 T cell activation#P00053>Gads#P01327;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Grb#P00848;PDGF signaling pathway#P00047>Grb2#P01148 HUMAN|HGNC=8057|UniProtKB=Q9UHK0 Q9UHK0 NUFIP1 PTHR13309:SF1 NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1 NUCLEAR FRAGILE X MENTAL RETARDATION-INTERACTING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;ribonucleoprotein complex assembly#GO:0022618;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=21248|UniProtKB=A2RRH5 A2RRH5 WDR27 PTHR44525:SF1 WD REPEAT-CONTAINING PROTEIN 27 WD REPEAT-CONTAINING PROTEIN 27 HUMAN|HGNC=17276|UniProtKB=O43414 O43414 ERI3 PTHR23044:SF68 3'-5' EXONUCLEASE ERI1-RELATED ERI1 EXORIBONUCLEASE 3 exoribonuclease#PC00099 HUMAN|HGNC=7838|UniProtKB=Q99801 Q99801 NKX3-1 PTHR24340:SF38 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-3.1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=25346|UniProtKB=Q5RHP9 Q5RHP9 ERICH3 PTHR23034:SF2 UNCHARACTERIZED GLUTAMATE-RICH PROTEIN 3 HUMAN|HGNC=20145|UniProtKB=P51810 P51810 GPR143 PTHR15177:SF2 G-PROTEIN COUPLED RECEPTOR 143 G-PROTEIN COUPLED RECEPTOR 143 G-protein coupled receptor#PC00021 HUMAN|HGNC=13010|UniProtKB=Q9NRE2 Q9NRE2 TSHZ2 PTHR12487:SF3 TEASHIRT-RELATED TEASHIRT HOMOLOG 2 binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=1568|UniProtKB=Q13939 Q13939 CCIN PTHR24412:SF163 KELCH PROTEIN CALICIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=23220|UniProtKB=Q7RTX7 Q7RTX7 CATSPER4 PTHR47077:SF1 ION_TRANS DOMAIN-CONTAINING PROTEIN CATION CHANNEL SPERM-ASSOCIATED PROTEIN 4 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;cation channel activity#GO:0005261;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 male gamete generation#GO:0048232;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;transport#GO:0006810;microtubule-based movement#GO:0007018;sperm motility#GO:0097722;cation transport#GO:0006812;spermatid differentiation#GO:0048515;cilium movement involved in cell motility#GO:0060294;cell differentiation#GO:0030154;establishment of localization#GO:0051234;spermatogenesis#GO:0007283;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;sperm capacitation#GO:0048240;cellular developmental process#GO:0048869;gamete generation#GO:0007276;metal ion transport#GO:0030001;monovalent inorganic cation transport#GO:0015672;multicellular organism reproduction#GO:0032504;ion transport#GO:0006811;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;multi-organism process#GO:0051704;cilium movement#GO:0003341;developmental process involved in reproduction#GO:0003006;localization#GO:0051179;cell development#GO:0048468;cilium-dependent cell motility#GO:0060285;spermatid development#GO:0007286;reproduction#GO:0000003;sodium ion transport#GO:0006814;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011 supramolecular complex#GO:0099080;outer dynein arm#GO:0036157;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;voltage-gated calcium channel complex#GO:0005891;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;intrinsic component of membrane#GO:0031224;microtubule cytoskeleton#GO:0015630;transmembrane transporter complex#GO:1902495;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;B axonemal microtubule#GO:0097650;catalytic complex#GO:1902494;ion channel complex#GO:0034702;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;cation channel complex#GO:0034703;sperm flagellum#GO:0036126;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503;plasma membrane#GO:0005886;axoneme#GO:0005930;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;cytoplasmic microtubule#GO:0005881;vacuole#GO:0005773;supramolecular polymer#GO:0099081;calcium channel complex#GO:0034704;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;axonemal outer doublet#GO:0097545;CatSper complex#GO:0036128;intracellular#GO:0005622;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;C1 axonemal microtubule#GO:1990719;membrane protein complex#GO:0098796;inner dynein arm#GO:0036156;intracellular vesicle#GO:0097708;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axonemal central pair#GO:0097540;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;sperm principal piece#GO:0097228;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;ciliary plasm#GO:0097014;dynein complex#GO:0030286;axonemal microtubule#GO:0005879 HUMAN|HGNC=24604|UniProtKB=Q9NYJ1 Q9NYJ1 COA4 PTHR13639:SF2 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL chaperone#PC00072 HUMAN|HGNC=34336|UniProtKB=A6NC97 A6NC97 FAM172BP PTHR21357:SF2 UNCHARACTERIZED PROTEIN FAM172B-RELATED RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;heterochromatin organization#GO:0070828;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;heterochromatin assembly#GO:0031507;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=29389|UniProtKB=A7MD48 A7MD48 SRRM4 PTHR34755:SF1 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED SERINE/ARGININE REPETITIVE MATRIX PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;RNA processing#GO:0006396;gene expression#GO:0010467;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;mRNA processing#GO:0006397;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18186|UniProtKB=Q9NS66 Q9NS66 GPR173 PTHR19268:SF4 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 173-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=11647|UniProtKB=Q13488 Q13488 TCIRG1 PTHR11629:SF21 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A3 inorganic molecular entity transmembrane transporter activity#GO:0015318;binding#GO:0005488;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;enzyme binding#GO:0019899;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 pH reduction#GO:0045851;regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;regulation of cellular pH#GO:0030641;vacuolar acidification#GO:0007035 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ATP synthase#PC00002 HUMAN|HGNC=11047|UniProtKB=Q9UN76 Q9UN76 SLC6A14 PTHR11616:SF286 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT NEUTRAL AND BASIC AMINO ACID TRANSPORTER B(0+) inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;neutral amino acid transmembrane transporter activity#GO:0015175;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 neutral amino acid transport#GO:0015804;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;L-alpha-amino acid transmembrane transport#GO:1902475;anion transport#GO:0006820;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;L-amino acid transport#GO:0015807;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;carboxylic acid transport#GO:0046942;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;sodium ion transport#GO:0006814;organic acid transmembrane transport#GO:1903825;sodium ion transmembrane transport#GO:0035725 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=20271|UniProtKB=Q8NEJ9 Q8NEJ9 NGDN PTHR13237:SF9 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED NEUROGUIDIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=26154|UniProtKB=Q2KHR3 Q2KHR3 QSER1 PTHR14709:SF2 UNCHARACTERIZED GLUTAMINE AND SERINE-RICH PROTEIN 1 HUMAN|HGNC=23160|UniProtKB=Q96F10 Q96F10 SAT2 PTHR10545:SF51 DIAMINE N-ACETYLTRANSFERASE DIAMINE ACETYLTRANSFERASE 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 HUMAN|HGNC=21308|UniProtKB=Q9NYP7 Q9NYP7 ELOVL5 PTHR11157:SF18 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 5 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=13568|UniProtKB=Q9NXJ5 Q9NXJ5 PGPEP1 PTHR23402:SF16 PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED PYROGLUTAMYL-PEPTIDASE 1 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cysteine protease#PC00081 HUMAN|HGNC=30925|UniProtKB=Q3LIE5 Q3LIE5 ADPRM PTHR16509:SF1 FAMILY NOT NAMED MANGANESE-DEPENDENT ADP-RIBOSE/CDP-ALCOHOL DIPHOSPHATASE HUMAN|HGNC=12859|UniProtKB=O00237 O00237 RNF103 PTHR15302:SF0 E3 UBIQUITIN-PROTEIN LIGASE RNF103 E3 UBIQUITIN-PROTEIN LIGASE RNF103 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=10956|UniProtKB=P46721 P46721 SLCO1A2 PTHR11388:SF16 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1A2 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=18269|UniProtKB=Q9P203 Q9P203 BTBD7 PTHR16064:SF5 BTB POZ DOMAIN CONTAINING 7 BTB/POZ DOMAIN-CONTAINING PROTEIN 7 HUMAN|HGNC=21146|UniProtKB=Q96E35 Q96E35 ZMYND19 PTHR46831:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 HUMAN|HGNC=15350|UniProtKB=Q8NGC8 Q8NGC8 OR11H7 PTHR24247:SF120 5-HYDROXYTRYPTAMINE RECEPTOR OLFACTORY RECEPTOR 11H7 cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=25736|UniProtKB=Q96BR6 Q96BR6 ZNF669 PTHR24381:SF386 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 669 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29207|UniProtKB=Q8N1G4 Q8N1G4 LRRC47 PTHR10947:SF3 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=29861|UniProtKB=Q9BU40 Q9BU40 CHRDL1 PTHR46303:SF2 VWFC DOMAIN-CONTAINING PROTEIN CHORDIN-LIKE PROTEIN 1 HUMAN|HGNC=11526|UniProtKB=P25103 P25103 TACR1 PTHR46925:SF4 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED SUBSTANCE-P RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of cellular component movement#GO:0051270;regulation of microtubule-based process#GO:0032886;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;regulation of localization#GO:0032879;sperm motility#GO:0097722;cell motility#GO:0048870;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;cilium movement involved in cell motility#GO:0060294;positive regulation of cellular component movement#GO:0051272;cilium movement#GO:0003341;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;cilium-dependent cell motility#GO:0060285;reproduction#GO:0000003;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;positive regulation of biological process#GO:0048518;locomotion#GO:0040011 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;B axonemal microtubule#GO:0097650;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 CCKR signaling map#P06959>TACR1#G06985;CCKR signaling map#P06959>TACR1#G07279 HUMAN|HGNC=4128|UniProtKB=Q8NCL4 Q8NCL4 GALNT6 PTHR11675:SF58 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 6 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=5273|UniProtKB=P98160 P98160 HSPG2 PTHR10574:SF273 NETRIN/LAMININ-RELATED BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;tissue development#GO:0009888 extracellular matrix protein#PC00102 HUMAN|HGNC=2799|UniProtKB=Q6ISB3 Q6ISB3 GRHL2 PTHR11037:SF17 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 2 HOMOLOG DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;neural tube development#GO:0021915;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=17084|UniProtKB=Q8WXH0 Q8WXH0 SYNE2 PTHR14514:SF4 PKA ANCHORING PROTEIN NESPRIN-2 HUMAN|HGNC=1113|UniProtKB=P32247 P32247 BRS3 PTHR45695:SF6 LEUCOKININ RECEPTOR-RELATED BOMBESIN RECEPTOR SUBTYPE-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=8212|UniProtKB=Q8NGR3 Q8NGR3 OR1K1 PTHR26451:SF965 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 1K1 HUMAN|HGNC=4549|UniProtKB=Q13098 Q13098 GPS1 PTHR14145:SF2 26S PROTESOME SUBUNIT 6 COP9 SIGNALOSOME COMPLEX SUBUNIT 1 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229 HUMAN|HGNC=25743|UniProtKB=Q4KMZ8 Q4KMZ8 NKAIN1 PTHR13084:SF4 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 1 localization#GO:0051179;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of transport#GO:0051049;regulation of sodium ion transport#GO:0002028;establishment of localization#GO:0051234;regulation of metal ion transport#GO:0010959;ion transport#GO:0006811;transport#GO:0006810;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of localization#GO:0032879;cation transport#GO:0006812 HUMAN|HGNC=25827|UniProtKB=Q6PF04 Q6PF04 ZNF613 PTHR24404:SF26 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 613 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9820|UniProtKB=O43502 O43502 RAD51C PTHR46239:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C DNA REPAIR PROTEIN RAD51 HOMOLOG 3 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;endodeoxyribonuclease activity#GO:0004520;four-way junction DNA binding#GO:0000400;deoxyribonuclease activity#GO:0004536 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;telophase#GO:0051326;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;M phase#GO:0000279;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;meiosis I cell cycle phase#GO:0098764;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;catalytic complex#GO:1902494;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;replication fork#GO:0005657 DNA metabolism protein#PC00009 HUMAN|HGNC=26344|UniProtKB=Q05D60 Q05D60 DEUP1 PTHR18875:SF5 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO DEUTEROSOME ASSEMBLY PROTEIN 1 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;epithelium development#GO:0060429;developmental process#GO:0032502;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;tissue development#GO:0009888;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 HUMAN|HGNC=4043|UniProtKB=Q13467 Q13467 FZD5 PTHR11309:SF136 FRIZZLED FRIZZLED-5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 HUMAN|HGNC=9586|UniProtKB=Q9Y6C5 Q9Y6C5 PTCH2 PTHR46022:SF3 PROTEIN PATCHED PROTEIN PATCHED HOMOLOG 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=3942|UniProtKB=P42345 P42345 MTOR PTHR11139:SF9 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE/THREONINE-PROTEIN KINASE MTOR transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;TOR signaling#GO:0031929;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;TORC1 signaling#GO:0038202;cellular response to stimulus#GO:0051716;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;regulation of macroautophagy#GO:0016241;regulation of cellular catabolic process#GO:0031329;negative regulation of autophagy#GO:0010507;negative regulation of macroautophagy#GO:0016242;cellular process#GO:0009987;response to stimulus#GO:0050896;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;TORC2 complex#GO:0031932;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Hypoxia response via HIF activation#P00030>TOR#P00817;p53 pathway by glucose deprivation#P04397>mTOR#P04638;Interleukin signaling pathway#P00036>mTOR#P00966;PDGF signaling pathway#P00047>mTOR#P01144 HUMAN|HGNC=6438|UniProtKB=Q9C075 Q9C075 KRT23 PTHR23239:SF44 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 23 HUMAN|HGNC=24740|UniProtKB=Q8N8J6 Q8N8J6 ZNF615 PTHR24376:SF194 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 615 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6865|UniProtKB=Q8IVH8 Q8IVH8 MAP4K3 PTHR48012:SF17 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;MAP kinase kinase activity#GO:0004708;protein kinase activity#GO:0004672 Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861 HUMAN|HGNC=15531|UniProtKB=Q99848 Q99848 EBNA1BP2 PTHR13028:SF0 RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED RRNA-PROCESSING PROTEIN EBP2-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;nuclear periphery#GO:0034399;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 HUMAN|HGNC=14565|UniProtKB=Q9BX66 Q9BX66 SORBS1 PTHR14167:SF64 SH3 DOMAIN-CONTAINING SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=8852|UniProtKB=O75192 O75192 PEX11A PTHR12652:SF22 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11A regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;biological regulation#GO:0065007;organelle fission#GO:0048285;cellular component organization#GO:0016043;cellular process#GO:0009987;peroxisome organization#GO:0007031;regulation of cellular component size#GO:0032535 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;microbody membrane#GO:0031903;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 HUMAN|HGNC=14870|UniProtKB=Q9BWW8 Q9BWW8 APOL6 PTHR14096:SF7 APOLIPOPROTEIN L APOLIPOPROTEIN L6 lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052 HUMAN|HGNC=25999|UniProtKB=Q9NXD2 Q9NXD2 MTMR10 PTHR10807:SF39 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 10 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=28035|UniProtKB=Q5SWH9 Q5SWH9 TMEM69 PTHR15887:SF4 TRANSMEMBRANE PROTEIN 69 TRANSMEMBRANE PROTEIN 69 HUMAN|HGNC=219|UniProtKB=O15072 O15072 ADAMTS3 PTHR13723:SF158 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 3 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=7716|UniProtKB=P49821 P49821 NDUFV1 PTHR11780:SF10 NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1 NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL oxidoreductase#PC00176 HUMAN|HGNC=2707|UniProtKB=P12821 P12821 ACE PTHR10514:SF25 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=8764|UniProtKB=O14737 O14737 PDCD5 PTHR10840:SF1 PROGRAMMED CELL DEATH PROTEIN 5 PROGRAMMED CELL DEATH PROTEIN 5 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=9234|UniProtKB=Q15648 Q15648 MED1 PTHR12881:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=19197|UniProtKB=Q7Z7J5 Q7Z7J5 DPPA2 PTHR16073:SF10 DCR DOMAIN-CONTAINING PROTEIN DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 2 HUMAN|HGNC=23709|UniProtKB=Q8NAM6 Q8NAM6 ZSCAN4 PTHR23226:SF88 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7434|UniProtKB=P13995 P13995 MTHFD2 PTHR48099:SF15 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;pteridine-containing compound metabolic process#GO:0042558;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Formyltetrahydroformate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 HUMAN|HGNC=11109|UniProtKB=Q969G3 Q969G3 SMARCE1 PTHR46232:SF2 SMARCE1 REGULATOR OF CHROMATIN SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;signaling receptor binding#GO:0005102;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;chromatin DNA binding#GO:0031490;nuclear receptor binding#GO:0016922;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;hormone receptor binding#GO:0051427 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=4030|UniProtKB=Q9H0Q3 Q9H0Q3 FXYD6 PTHR14132:SF15 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 6-RELATED cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of sodium ion transport#GO:0002028;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;sodium ion transport#GO:0006814;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;sodium ion transmembrane transport#GO:0035725 primary active transporter#PC00068 HUMAN|HGNC=13477|UniProtKB=A0A1B0GUS4 A0A1B0GUS4 UBE2L5 PTHR24068:SF170 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 L5 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein K11-linked ubiquitination#GO:0070979;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>UbcH7#P01224;Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=7049|UniProtKB=Q09328 Q09328 MGAT5 PTHR15075:SF5 ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=14676|UniProtKB=Q9BYS8 Q9BYS8 LRRC2 PTHR45752:SF37 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9677|UniProtKB=Q92932 Q92932 PTPRN2 PTHR46106:SF5 IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE N2 protein phosphatase#PC00195 HUMAN|HGNC=9592|UniProtKB=P41222 P41222 PTGDS PTHR11430:SF86 LIPOCALIN PROSTAGLANDIN-H2 D-ISOMERASE transfer/carrier protein#PC00219 HUMAN|HGNC=27596|UniProtKB=Q6ZMC9 Q6ZMC9 SIGLEC15 PTHR46942:SF1 SIALIC ACID-BINDING IG-LIKE LECTIN 15 SIALIC ACID-BINDING IG-LIKE LECTIN 15 animal organ development#GO:0048513;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;regulation of cell differentiation#GO:0045595;bone development#GO:0060348;regulation of biological process#GO:0050789;tissue remodeling#GO:0048771;osteoclast differentiation#GO:0030316;system development#GO:0048731;regulation of cytoskeleton organization#GO:0051493;cell differentiation#GO:0030154;bone remodeling#GO:0046849;actin filament-based process#GO:0030029;regulation of hemopoiesis#GO:1903706;tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;bone resorption#GO:0045453;regulation of tissue remodeling#GO:0034103;hemopoiesis#GO:0030097;regulation of actin cytoskeleton organization#GO:0032956;regulation of immune system process#GO:0002682;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;anatomical structure homeostasis#GO:0060249;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;immune system development#GO:0002520;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;immune system process#GO:0002376;multicellular organismal homeostasis#GO:0048871;leukocyte differentiation#GO:0002521;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of bone resorption#GO:0045124;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;regulation of bone remodeling#GO:0046850 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=30513|UniProtKB=Q96AH8 Q96AH8 RAB7B PTHR47981:SF22 RAB FAMILY RAS-RELATED PROTEIN RAB-7B lysosome organization#GO:0007040;vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;endosome to lysosome transport#GO:0008333;cellular process#GO:0009987;lysosomal transport#GO:0007041;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=11272|UniProtKB=P02549 P02549 SPTA1 PTHR11915:SF431 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN ALPHA CHAIN, ERYTHROCYTIC 1 HUMAN|HGNC=20824|UniProtKB=Q86WK6 Q86WK6 AMIGO1 PTHR24368:SF1 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 1 head development#GO:0060322;system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;brain development#GO:0007420;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=32686|UniProtKB=A6NK02 A6NK02 TRIM75P PTHR24103:SF312 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 75-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=33104|UniProtKB=Q3SY52 Q3SY52 ZIK1 PTHR24377:SF688 IP01015P-RELATED ZINC FINGER PROTEIN INTERACTING WITH RIBONUCLEOPROTEIN K cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=30300|UniProtKB=Q9GZS3 Q9GZS3 WDR61 PTHR44090:SF1 WD REPEAT-CONTAINING PROTEIN 61 WD REPEAT-CONTAINING PROTEIN 61 HUMAN|HGNC=190|UniProtKB=O43184 O43184 ADAM12 PTHR11905:SF112 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 12 metalloprotease#PC00153 HUMAN|HGNC=29329|UniProtKB=Q9HCE9 Q9HCE9 ANO8 PTHR12308:SF51 NGEP-RELATED ANOCTAMIN-8 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=30382|UniProtKB=Q0VDG4 Q0VDG4 SCRN3 PTHR12994:SF18 SECERNIN SECERNIN-3 HUMAN|HGNC=17062|UniProtKB=Q5JVS0 Q5JVS0 HABP4 PTHR12299:SF30 HYALURONIC ACID-BINDING PROTEIN 4 INTRACELLULAR HYALURONAN-BINDING PROTEIN 4 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of translational initiation#GO:0045948;gene expression#GO:0010467;regulation of translational initiation#GO:0006446;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;biosynthetic process#GO:0009058;translation#GO:0006412;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;translational initiation#GO:0006413;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=30469|UniProtKB=Q6PJQ5 Q6PJQ5 FOXR2 PTHR46789:SF2 FORKHEAD BOX PROTEIN R1 FORKHEAD BOX PROTEIN R2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=16247|UniProtKB=Q5JXA9 Q5JXA9 SIRPB2 PTHR19971:SF9 SIGNAL-REGULATORY PROTEIN BETA SIGNAL-REGULATORY PROTEIN BETA-2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=19739|UniProtKB=Q86TZ1 Q86TZ1 TTC6 PTHR44858:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 6 TETRATRICOPEPTIDE REPEAT PROTEIN 6 HUMAN|HGNC=26582|UniProtKB=Q8N2C7 Q8N2C7 UNC80 PTHR31781:SF1 UNC80 PROTEIN UNC-80 HOMOLOG cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 biological regulation#GO:0065007;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;ion homeostasis#GO:0050801;chemical homeostasis#GO:0048878;regulation of biological quality#GO:0065008 membrane protein complex#GO:0098796;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=10660|UniProtKB=O75056 O75056 SDC3 PTHR10915:SF7 SYNDECAN SYNDECAN-3 localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 transmembrane signal receptor#PC00197 HUMAN|HGNC=905|UniProtKB=P30530 P30530 AXL PTHR24416:SF323 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR UFO signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;immune system development#GO:0002520;phagocytosis#GO:0006909;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;regulation of body fluid levels#GO:0050878;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;negative regulation of cell death#GO:0060548;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;response to wounding#GO:0009611;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;protein kinase B signaling#GO:0043491;positive regulation of protein kinase B signaling#GO:0051897;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;platelet activation#GO:0030168;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;transport#GO:0006810;hematopoietic or lymphoid organ development#GO:0048534;positive regulation of molecular function#GO:0044093;wound healing#GO:0042060;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;hemopoiesis#GO:0030097;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;lymphocyte activation#GO:0046649;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell motility#GO:0048870;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;hemostasis#GO:0007599;coagulation#GO:0050817;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;lymphocyte differentiation#GO:0030098;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of kinase activity#GO:0033674;blood coagulation#GO:0007596;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;regulation of protein kinase B signaling#GO:0051896 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=16398|UniProtKB=Q9BXW6 Q9BXW6 OSBPL1A PTHR10972:SF53 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 1 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;cholesterol binding#GO:0015485 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7776|UniProtKB=Q13469 Q13469 NFATC2 PTHR12533:SF4 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772 positive regulation of gene expression#GO:0010628;calcium-mediated signaling#GO:0019722;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252 Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;CCKR signaling map#P06959>NFAT1#P07176;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Axon guidance mediated by netrin#P00009>NFAT#P00359;Wnt signaling pathway#P00057>NFAT#P01452;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367 HUMAN|HGNC=20368|UniProtKB=Q5T200 Q5T200 ZC3H13 PTHR13585:SF19 CHASCON, ISOFORM D-RELATED ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13 HUMAN|HGNC=8944|UniProtKB=Q9UIV8 Q9UIV8 SERPINB13 PTHR11461:SF161 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B13 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=24286|UniProtKB=Q9Y3A4 Q9Y3A4 RRP7A PTHR13191:SF0 RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 HUMAN|HGNC=3969|UniProtKB=P23945 P23945 FSHR PTHR24372:SF5 GLYCOPROTEIN HORMONE RECEPTOR FOLLICLE-STIMULATING HORMONE RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 reproductive system development#GO:0061458;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;rhythmic process#GO:0048511;cellular process involved in reproduction in multicellular organism#GO:0022412;animal organ development#GO:0048513;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;hormone-mediated signaling pathway#GO:0009755;reproductive structure development#GO:0048608;regulation of biological process#GO:0050789;system development#GO:0048731;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609;male sex differentiation#GO:0046661;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;multicellular organism reproduction#GO:0032504;cellular response to organic substance#GO:0071310;multicellular organism development#GO:0007275;sex differentiation#GO:0007548;male gonad development#GO:0008584;cell communication#GO:0007154;cellular process#GO:0009987;developmental process involved in reproduction#GO:0003006;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to hormone#GO:0009725;reproduction#GO:0000003;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=935|UniProtKB=O14867 O14867 BACH1 PTHR46105:SF1 AGAP004733-PA TRANSCRIPTION REGULATOR PROTEIN BACH1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12904|UniProtKB=P58317 P58317 ZNF121 PTHR24377:SF929 IP01015P-RELATED ZINC FINGER PROTEIN 121 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24457|UniProtKB=Q8N9I9 Q8N9I9 DTX3 PTHR12622:SF35 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX3-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=29652|UniProtKB=Q9BQA1 Q9BQA1 WDR77 PTHR46853:SF1 METHYLOSOME PROTEIN 50 METHYLOSOME PROTEIN 50 sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;small molecule binding#GO:0036094;organic cyclic compound binding#GO:0097159;binding#GO:0005488;DNA binding#GO:0003677;transcription coactivator activity#GO:0003713;nucleoside phosphate binding#GO:1901265;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;nuclear receptor transcription coactivator activity#GO:0030374 reproductive system development#GO:0061458;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;positive regulation of cell population proliferation#GO:0008284;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;reproductive structure development#GO:0048608;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;epithelial cell proliferation#GO:0050673;reproductive process#GO:0022414;multi-organism reproductive process#GO:0044703;positive regulation of biological process#GO:0048518;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;gamete generation#GO:0007276;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;cellular process involved in reproduction in multicellular organism#GO:0022412;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;system development#GO:0048731;negative regulation of multicellular organismal process#GO:0051241;urogenital system development#GO:0001655;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of cell population proliferation#GO:0008285;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;gland development#GO:0048732;regulation of cell population proliferation#GO:0042127;multicellular organism reproduction#GO:0032504;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;epithelial cell differentiation#GO:0030855;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of reproductive process#GO:2000241;regulation of RNA metabolic process#GO:0051252;multi-organism process#GO:0051704;tissue development#GO:0009888;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=3495|UniProtKB=P41212 P41212 ETV6 PTHR11849:SF19 ETS TRANSCRIPTION FACTOR ETV6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=13164|UniProtKB=P62633 P62633 CNBP PTHR23002:SF67 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN CELLULAR NUCLEIC ACID-BINDING PROTEIN single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;positive regulation of cellular protein metabolic process#GO:0032270;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=23414|UniProtKB=Q9Y4E1 Q9Y4E1 WASHC2C PTHR21669:SF1 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS WASH COMPLEX SUBUNIT 2A-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=30946|UniProtKB=A6NK53 A6NK53 ZNF233 PTHR24377:SF705 IP01015P-RELATED ZINC FINGER PROTEIN 233 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18357|UniProtKB=Q9P2F6 Q9P2F6 ARHGAP20 PTHR23179:SF28 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED RHO GTPASE-ACTIVATING PROTEIN 20 GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257 HUMAN|HGNC=7634|UniProtKB=Q13075 Q13075 NAIP PTHR46914:SF1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 cysteine-type peptidase activity#GO:0008234;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;cysteine-type endopeptidase inhibitor activity#GO:0004869;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096;ATP binding#GO:0005524 response to external biotic stimulus#GO:0043207;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;negative regulation of endopeptidase activity#GO:0010951;detection of stimulus#GO:0051606;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;negative regulation of cell death#GO:0060548;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043154;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;response to bacterium#GO:0009617;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell death#GO:0010941;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 inflammasome complex#GO:0061702;cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 viral or transposable element protein#PC00237 HUMAN|HGNC=3555|UniProtKB=P07148 P07148 FABP1 PTHR11955:SF96 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, LIVER HUMAN|HGNC=10786|UniProtKB=Q08170 Q08170 SRSF4 PTHR23147:SF55 SERINE/ARGININE RICH SPLICING FACTOR SERINE/ARGININE-RICH SPLICING FACTOR 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=18916|UniProtKB=A8MUX0 A8MUX0 KRTAP16-1 PTHR23262:SF55 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 16-1 HUMAN|HGNC=3573|UniProtKB=Q13158 Q13158 FADD PTHR15077:SF10 FAS-ASSOCIATING DEATH DOMAIN-CONTAINING PROTEIN FADD FAS-ASSOCIATED DEATH DOMAIN PROTEIN FAS signaling pathway#P00020>FADD#P00622;Apoptosis signaling pathway#P00006>FADD#P00327 HUMAN|HGNC=28869|UniProtKB=Q7Z5V6 Q7Z5V6 PPP1R32 PTHR34349:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 32 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 32 phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 phosphatase modulator#PC00184 HUMAN|HGNC=943|UniProtKB=O14514 O14514 ADGRB1 PTHR12011:SF39 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR B1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;membrane organization#GO:0061024;regulation of cyclase activity#GO:0031279;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;vesicle organization#GO:0016050;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;phagocytosis#GO:0006909;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;apoptotic cell clearance#GO:0043277;cyclic-nucleotide-mediated signaling#GO:0019935 synapse#GO:0045202;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;asymmetric synapse#GO:0032279;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 p53 pathway#P00059>BAI-1#G04699 HUMAN|HGNC=14561|UniProtKB=O43307 O43307 ARHGEF9 PTHR45834:SF6 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=14046|UniProtKB=P82921 P82921 MRPS21 PTHR21109:SF13 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S21 28S RIBOSOMAL PROTEIN S21, MITOCHONDRIAL ribosomal protein#PC00202 HUMAN|HGNC=13546|UniProtKB=Q9NRF9 Q9NRF9 POLE3 PTHR46172:SF1 DNA POLYMERASE EPSILON SUBUNIT 3 DNA POLYMERASE EPSILON SUBUNIT 3 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;heterochromatin organization#GO:0070828;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;nucleosome organization#GO:0034728;negative regulation of biological process#GO:0048519;chromatin assembly or disassembly#GO:0006333;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;cellular nitrogen compound catabolic process#GO:0044270;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;heterochromatin assembly#GO:0031507;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;regulation of nucleic acid-templated transcription#GO:1903506;cellular macromolecule catabolic process#GO:0044265;DNA replication#GO:0006260;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259;DNA strand elongation involved in DNA replication#GO:0006271 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 HUMAN|HGNC=1122|UniProtKB=P43251 P43251 BTD PTHR10609:SF14 BIOTINIDASE-RELATED BIOTINIDASE hydrolase#PC00121 HUMAN|HGNC=28177|UniProtKB=Q567V2 Q567V2 MPV17L2 PTHR11266:SF8 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN 2 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=23780|UniProtKB=Q5JVG8 Q5JVG8 ZNF506 PTHR24384:SF180 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 506 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=6172|UniProtKB=P46977 P46977 STT3A PTHR13872:SF43 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;post-translational protein modification#GO:0043687;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 glycosyltransferase#PC00111 HUMAN|Ensembl=ENSG00000284555|UniProtKB=A0A2R8YCY7 A0A2R8YCY7 ENSG00000284555 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=16386|UniProtKB=Q96SU4 Q96SU4 OSBPL9 PTHR10972:SF200 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9 lipid binding#GO:0008289;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;lipid transporter activity#GO:0005319;steroid binding#GO:0005496;sterol binding#GO:0032934 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=1339|UniProtKB=P13671 P13671 C6 PTHR45742:SF4 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C6 HUMAN|HGNC=12261|UniProtKB=Q13061 Q13061 TRDN PTHR14106:SF0 TRIADIN TRIADIN HUMAN|HGNC=25896|UniProtKB=Q96D31 Q96D31 ORAI1 PTHR31501:SF3 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812;calcium ion transport#GO:0006816 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133 HUMAN|HGNC=6168|UniProtKB=Q06033 Q06033 ITIH3 PTHR10338:SF115 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H3 protease inhibitor#PC00191 HUMAN|HGNC=8840|UniProtKB=P12955 P12955 PEPD PTHR43226:SF1 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO DIPEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153 HUMAN|HGNC=15001|UniProtKB=Q8NGZ0 Q8NGZ0 OR2AJ1 PTHR26453:SF214 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AJ1 transmembrane signal receptor#PC00197 HUMAN|HGNC=7179|UniProtKB=Q02252 Q02252 ALDH6A1 PTHR43866:SF3 MALONATE-SEMIALDEHYDE DEHYDROGENASE METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086 dehydrogenase#PC00092 Pyrimidine Metabolism#P02771>Methylmalonate Semialdehyde Dehydrogenase#P03124 HUMAN|HGNC=20796|UniProtKB=Q6ZTQ3 Q6ZTQ3 RASSF6 PTHR22738:SF3 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 6 scaffold/adaptor protein#PC00226 HUMAN|HGNC=4046|UniProtKB=Q9H461 Q9H461 FZD8 PTHR11309:SF90 FRIZZLED FRIZZLED-8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Fzd#P00189;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 HUMAN|HGNC=22200|UniProtKB=Q7L0X0 Q7L0X0 TRIL PTHR24373:SF307 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TLR4 INTERACTOR WITH LEUCINE RICH REPEATS carbohydrate derivative binding#GO:0097367;lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;binding#GO:0005488 signal transduction#GO:0007165;gene expression#GO:0010467;regulation of cytokine production involved in immune response#GO:0002718;pattern recognition receptor signaling pathway#GO:0002221;cytokine production#GO:0001816;toll-like receptor 4 signaling pathway#GO:0034142;production of molecular mediator of immune response#GO:0002440;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;regulation of immune response#GO:0050776;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of immune effector process#GO:0002697;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of production of molecular mediator of immune response#GO:0002700;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222 receptor complex#GO:0043235;membrane protein complex#GO:0098796;extracellular matrix#GO:0031012;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=6695|UniProtKB=O75074 O75074 LRP3 PTHR24270:SF22 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 3 apolipoprotein#PC00052 Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 HUMAN|HGNC=26887|UniProtKB=Q6NXT6 Q6NXT6 TAPT1 PTHR13317:SF4 UNCHARACTERIZED TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;cellular protein localization#GO:0034613;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=20810|UniProtKB=O94892 O94892 ZNF432 PTHR24377:SF165 IP01015P-RELATED ZINC FINGER PROTEIN 432 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26324|UniProtKB=Q96LR7 Q96LR7 C2orf50 PTHR31909:SF2 CHROMOSOME 20 ORF85 FAMILY MEMBER RIKEN CDNA 2410004P03 GENE HUMAN|HGNC=2176|UniProtKB=Q9UQ52 Q9UQ52 CNTN6 PTHR10075:SF45 BASIGIN RELATED CONTACTIN-6 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=659|UniProtKB=P62330 P62330 ARF6 PTHR11711:SF322 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 G-protein#PC00020 Integrin signalling pathway#P00034>Arf6#P00919;Huntington disease#P00029>ARF#P00786 HUMAN|HGNC=4082|UniProtKB=P47870 P47870 GABRB2 PTHR18945:SF221 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-2 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;system process#GO:0003008;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=11301|UniProtKB=P61011 P61011 SRP54 PTHR11564:SF5 SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54 SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN RNA metabolism protein#PC00031 HUMAN|HGNC=15191|UniProtKB=A0A3B3IT45 A0A3B3IT45 OR51C1P PTHR26450:SF408 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR transmembrane signal receptor#PC00197 HUMAN|HGNC=23700|UniProtKB=Q9H892 Q9H892 TTC12 PTHR46540:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 12 TETRATRICOPEPTIDE REPEAT PROTEIN 12 HUMAN|HGNC=6296|UniProtKB=O43526 O43526 KCNQ2 PTHR11537:SF6 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;calmodulin binding#GO:0005516;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>K+ channel#P01070 HUMAN|HGNC=24983|UniProtKB=A6NNZ2 A6NNZ2 TUBB8B PTHR11588:SF55 TUBULIN TUBULIN BETA 8B-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 HUMAN|HGNC=24544|UniProtKB=Q9H6Y7 Q9H6Y7 RNF167 PTHR22765:SF35 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF167 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 negative regulation of biological process#GO:0048519;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=30892|UniProtKB=Q7Z6Z7 Q7Z6Z7 HUWE1 PTHR11254:SF67 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HUWE1 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 HUMAN|HGNC=29800|UniProtKB=Q70IA8 Q70IA8 MOB3C PTHR22599:SF12 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3C kinase activator#PC00138 HUMAN|HGNC=21577|UniProtKB=Q8NB78 Q8NB78 KDM1B PTHR10742:SF350 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 1B oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 HUMAN|HGNC=199|UniProtKB=O43506 O43506 ADAM20 PTHR11905:SF232 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 20 developmental process involved in reproduction#GO:0003006;reproductive system development#GO:0061458;system development#GO:0048731;reproduction#GO:0000003;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;sex differentiation#GO:0007548;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;male gonad development#GO:0008584;male sex differentiation#GO:0046661;reproductive structure development#GO:0048608 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=38652|UniProtKB=D6RF30 D6RF30 GOLGA8K PTHR10881:SF62 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8H-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=19127|UniProtKB=O95057 O95057 DIRAS1 PTHR24070:SF213 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=28096|UniProtKB=Q5T7R7 Q5T7R7 C1orf185 PTHR37858:SF1 HYPOTHETICAL PROTEIN LOC689589 HYPOTHETICAL PROTEIN LOC689589 HUMAN|HGNC=3953|UniProtKB=P62166 P62166 NCS1 PTHR23055:SF103 CALCIUM BINDING PROTEINS NEURONAL CALCIUM SENSOR 1 HUMAN|HGNC=15246|UniProtKB=Q8NGI1 Q8NGI1 OR56B2P PTHR26450:SF26 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56B2-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=14860|UniProtKB=Q92575 Q92575 UBXN4 PTHR46424:SF1 UBX DOMAIN-CONTAINING PROTEIN 4 UBX DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=26150|UniProtKB=Q53R41 Q53R41 FASTKD1 PTHR21228:SF29 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL HUMAN|HGNC=2436|UniProtKB=P32927 P32927 CSF2RB PTHR23037:SF22 CYTOKINE RECEPTOR CYTOKINE RECEPTOR COMMON SUBUNIT BETA transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 HUMAN|HGNC=18681|UniProtKB=Q7L014 Q7L014 DDX46 PTHR24031:SF25 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX46-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=7780|UniProtKB=Q16621 Q16621 NFE2 PTHR24411:SF26 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR TRANSCRIPTION FACTOR NF-E2 45 KDA SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=29509|UniProtKB=Q96BI3 Q96BI3 APH1A PTHR12889:SF3 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1A hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;proteolysis#GO:0006508;biological regulation#GO:0065007;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;Notch signaling pathway#GO:0007219 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;intrinsic component of plasma membrane#GO:0031226;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 protease#PC00190 Alzheimer disease-presenilin pathway#P00004>Aph-1#P00170;Notch signaling pathway#P00045>Aph-1#P01109;Alzheimer disease-amyloid secretase pathway#P00003>Aph-1#P00091 HUMAN|HGNC=10750|UniProtKB=Q9UH03 Q9UH03 SEPTIN3 PTHR18884:SF62 SEPTIN NEURONAL-SPECIFIC SEPTIN-3 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cell division#GO:0051301;cellular localization#GO:0051641;membrane fission#GO:0090148;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytokinesis#GO:0000910 presynapse#GO:0098793;synapse#GO:0045202;cell junction#GO:0030054;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell division site#GO:0032153;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=52|UniProtKB=Q5T3U5 Q5T3U5 ABCC10 PTHR24223:SF330 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 7 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=25372|UniProtKB=Q96SY0 Q96SY0 INTS14 PTHR13532:SF3 UNCHARACTERIZED INTEGRATOR COMPLEX SUBUNIT 14 HUMAN|HGNC=2687|UniProtKB=O60477 O60477 BRINP1 PTHR15564:SF7 MACPF DOMAIN-CONTAINING PROTEIN BMP/RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 1 HUMAN|HGNC=27981|UniProtKB=Q8NEM8 Q8NEM8 AGBL3 PTHR12756:SF23 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 3 metalloprotease#PC00153 HUMAN|HGNC=5549|UniProtKB=A0A0C4DH31 A0A0C4DH31 IGHV1-18 PTHR23266:SF304 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-18 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=20713|UniProtKB=Q8WVZ1 Q8WVZ1 ZDHHC19 PTHR22883:SF326 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC19 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=23294|UniProtKB=Q5T681 Q5T681 C10orf62 PTHR23008:SF0 CHROMOSOME 28 C10ORF62 HOMOLOG CHROMOSOME 28 C10ORF62 HOMOLOG HUMAN|HGNC=23679|UniProtKB=Q5T953 Q5T953 IER5L PTHR15895:SF11 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 5-LIKE PROTEIN HUMAN|HGNC=9185|UniProtKB=Q9NP87 Q9NP87 POLM PTHR11276:SF24 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA-DIRECTED DNA/RNA POLYMERASE MU transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;DNA polymerase activity#GO:0034061;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-directed DNA polymerase#PC00018 HUMAN|HGNC=23109|UniProtKB=Q6V0I7 Q6V0I7 FAT4 PTHR24026:SF112 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN FAT 4 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=20803|UniProtKB=Q96K37 Q96K37 SLC35E1 PTHR11132:SF427 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E1 secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=6321|UniProtKB=O14782 O14782 KIF3C PTHR24115:SF734 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3C pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=19056|UniProtKB=Q2M2E3 Q2M2E3 ODF4 PTHR10671:SF94 EPITHELIAL MEMBRANE PROTEIN-RELATED OUTER DENSE FIBER PROTEIN 4 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=28599|UniProtKB=Q8NEF3 Q8NEF3 CCDC112 PTHR21549:SF0 MUTATED IN BLADDER CANCER 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 112 HUMAN|HGNC=1160|UniProtKB=Q96RR1 Q96RR1 TWNK PTHR12873:SF0 T7-LIKE MITOCHONDRIAL DNA HELICASE TWINKLE PROTEIN, MITOCHONDRIAL nucleic acid binding#GO:0003676;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;single-stranded DNA binding#GO:0003697;DNA-dependent ATPase activity#GO:0008094;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA helicase#PC00011 HUMAN|HGNC=25568|UniProtKB=Q9NVI1 Q9NVI1 FANCI PTHR21818:SF0 BC025462 PROTEIN FANCONI ANEMIA GROUP I PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 HUMAN|HGNC=24778|UniProtKB=A4D1S0 A4D1S0 KLRG2 PTHR47606:SF1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY G MEMBER 2 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY G MEMBER 2 transmembrane signal receptor#PC00197 HUMAN|HGNC=20822|UniProtKB=Q9HBW9 Q9HBW9 ADGRL4 PTHR12011:SF59 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR L4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=21298|UniProtKB=Q86V21 Q86V21 AACS PTHR42921:SF1 ACETOACETYL-COA SYNTHETASE ACETOACETYL-COA SYNTHETASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 HUMAN|HGNC=32286|UniProtKB=P0DPD5 P0DPD5 ZNF723 PTHR24384:SF203 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 723 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=40023|UniProtKB=A6NHS7 A6NHS7 MANSC4 PTHR16021:SF11 MANSC DOMAIN CONTAINING PROTEIN 1 MANSC DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=11285|UniProtKB=P31213 P31213 SRD5A2 PTHR10556:SF37 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;lipid biosynthetic process#GO:0008610;organic cyclic compound biosynthetic process#GO:1901362;steroid biosynthetic process#GO:0006694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 dehydrogenase#PC00092 HUMAN|HGNC=13135|UniProtKB=Q6ZN08 Q6ZN08 ZNF66 PTHR24384:SF214 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 66-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=17020|UniProtKB=Q9Y616 Q9Y616 IRAK3 PTHR24419:SF7 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;nuclear division#GO:0000280;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;mitotic cell cycle#GO:0000278;regulation of MAP kinase activity#GO:0043405;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;regulation of multicellular organismal process#GO:0051239;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;cytokine production#GO:0001816;phosphate-containing compound metabolic process#GO:0006796;negative regulation of multicellular organismal process#GO:0051241;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;nucleic acid-templated transcription#GO:0097659;negative regulation of MAP kinase activity#GO:0043407;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of DNA-binding transcription factor activity#GO:0051091;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;cell cycle#GO:0007049;regulation of nucleic acid-templated transcription#GO:1903506;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092;negative regulation of gene expression#GO:0010629;regulation of protein modification process#GO:0031399;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;transcription, DNA-templated#GO:0006351;negative regulation of MAPK cascade#GO:0043409;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;RNA biosynthetic process#GO:0032774;negative regulation of protein metabolic process#GO:0051248;regulation of response to stimulus#GO:0048583;response to interleukin-1#GO:0070555;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;regulation of phosphate metabolic process#GO:0019220;tumor necrosis factor production#GO:0032640;macromolecule modification#GO:0043412;mitotic cell cycle process#GO:1903047;regulation of transcription, DNA-templated#GO:0006355;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;negative regulation of transferase activity#GO:0051348;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;cellular macromolecule biosynthetic process#GO:0034645;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 Toll receptor signaling pathway#P00054>IRAKM#P01378 HUMAN|Ensembl=ENSG00000274563|UniProtKB=A0A0G2JNG1 A0A0G2JNG1 ENSG00000274563 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=2480|UniProtKB=O60676 O60676 CST8 PTHR47010:SF1 CYSTATIN-8-RELATED CYSTATIN-8 cytoplasm#GO:0005737;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 HUMAN|HGNC=11371|UniProtKB=Q9NUL3 Q9NUL3 STAU2 PTHR46054:SF1 MATERNAL EFFECT PROTEIN STAUFEN DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 2 HUMAN|HGNC=15007|UniProtKB=Q8NGZ5 Q8NGZ5 OR2G2 PTHR26453:SF132 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2G2 transmembrane signal receptor#PC00197 HUMAN|HGNC=4570|UniProtKB=Q9UBQ7 Q9UBQ7 GRHPR PTHR10996:SF137 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE/HYDROXYPYRUVATE REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=19694|UniProtKB=Q6ZWJ1 Q6ZWJ1 STXBP4 PTHR19964:SF16 MULTIPLE PDZ DOMAIN PROTEIN SYNTAXIN-BINDING PROTEIN 4 HUMAN|HGNC=8029|UniProtKB=O95631 O95631 NTN1 PTHR10574:SF378 NETRIN/LAMININ-RELATED NETRIN-1 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;dendrite development#GO:0016358;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;motor neuron axon guidance#GO:0008045;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 HUMAN|HGNC=30053|UniProtKB=Q6UQ28 Q6UQ28 PLET1 PTHR22527:SF2 UNCHARACTERIZED PLACENTA-EXPRESSED TRANSCRIPT 1 PROTEIN negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;epithelium development#GO:0060429;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of localization#GO:0032879;wound healing#GO:0042060;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;positive regulation of cell motility#GO:2000147;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of cellular component movement#GO:0051270;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cell adhesion#GO:0007155;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;response to wounding#GO:0009611;positive regulation of cell migration#GO:0030335;response to stress#GO:0006950;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;cell migration#GO:0016477;locomotion#GO:0040011 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177 HUMAN|HGNC=4004|UniProtKB=Q96AE4 Q96AE4 FUBP1 PTHR10288:SF99 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=13201|UniProtKB=Q9H324 Q9H324 ADAMTS10 PTHR13723:SF26 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 10 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=9676|UniProtKB=Q16849 Q16849 PTPRN PTHR46106:SF1 IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE-LIKE N protein phosphatase#PC00195 HUMAN|HGNC=962|UniProtKB=Q9UIF9 Q9UIF9 BAZ2A PTHR45915:SF5 TRANSCRIPTION INTERMEDIARY FACTOR BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=871|UniProtKB=Q9UII2 Q9UII2 ATP5IF1 PTHR23407:SF6 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE ATPASE INHIBITOR, MITOCHONDRIAL pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;ligase activity#GO:0016874;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;enzyme inhibitor activity#GO:0004857;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;negative regulation of hydrolase activity#GO:0051346;pteridine-containing compound metabolic process#GO:0042558;porphyrin-containing compound metabolic process#GO:0006778;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;heme biosynthetic process#GO:0006783;carboxylic acid biosynthetic process#GO:0046394;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;pigment biosynthetic process#GO:0046148;regulation of hydrolase activity#GO:0051336;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;tetrapyrrole metabolic process#GO:0033013;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;amide biosynthetic process#GO:0043604;folic acid-containing compound biosynthetic process#GO:0009396;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092;cellular amide metabolic process#GO:0043603;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 HUMAN|HGNC=32266|UniProtKB=A6NE21 A6NE21 FAM90A19P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=8665|UniProtKB=Q9Y5I1 Q9Y5I1 PCDHA11 PTHR24028:SF68 CADHERIN-87A PROTOCADHERIN ALPHA-11 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=11898|UniProtKB=P98066 P98066 TNFAIP6 PTHR46908:SF1 CUBILIN-LIKE PROTEIN TUMOR NECROSIS FACTOR-INDUCIBLE GENE 6 PROTEIN negative regulation of biological process#GO:0048519;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;negative regulation of inflammatory response#GO:0050728;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of inflammatory response#GO:0050727;response to stress#GO:0006950;regulation of defense response#GO:0031347;negative regulation of response to external stimulus#GO:0032102;biological regulation#GO:0065007;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=32484|UniProtKB=A6NNM8 A6NNM8 TTLL13P PTHR12241:SF91 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL13P cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=25455|UniProtKB=Q969E8 Q969E8 TSR2 PTHR21250:SF0 UNCHARACTERIZED PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=32576|UniProtKB=A2VCK2 A2VCK2 DCDC2B PTHR23004:SF10 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2B supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;cortical cytoskeleton#GO:0030863;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;cortical actin cytoskeleton#GO:0030864;supramolecular fiber#GO:0099512;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874 HUMAN|HGNC=22971|UniProtKB=P60411 P60411 KRTAP10-9 PTHR23262:SF175 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-1-RELATED HUMAN|HGNC=18603|UniProtKB=Q9BXS0 Q9BXS0 COL25A1 PTHR24020:SF4 COLLAGEN ALPHA COLLAGEN ALPHA-1(VII) CHAIN-RELATED extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=5860|UniProtKB=P0CF74 P0CF74 IGLC6 PTHR23266:SF345 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA CONSTANT 6 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=17980|UniProtKB=Q96LB0 Q96LB0 MRGPRX3 PTHR11334:SF34 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MEMBER X3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=2336|UniProtKB=P20023 P20023 CR2 PTHR19325:SF391 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT RECEPTOR TYPE 2 HUMAN|HGNC=19978|UniProtKB=Q8NBN7 Q8NBN7 RDH13 PTHR43157:SF31 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED glycosyltransferase#PC00111 HUMAN|HGNC=17103|UniProtKB=Q9Y5L0 Q9Y5L0 TNPO3 PTHR12363:SF42 TRANSPORTIN 3 AND IMPORTIN 13 TRANSPORTIN-3 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=11913|UniProtKB=Q02223 Q02223 TNFRSF17 PTHR20437:SF0 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 13/17 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17 transmembrane signal receptor#PC00197 HUMAN|HGNC=23695|UniProtKB=Q155Q3 Q155Q3 DIXDC1 PTHR10878:SF22 SEGMENT POLARITY PROTEIN DISHEVELLED DIXIN regulation of biological process#GO:0050789;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17108|UniProtKB=Q8TE57 Q8TE57 ADAMTS16 PTHR13723:SF140 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 16 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=25639|UniProtKB=Q49AR2 Q49AR2 C5orf22 PTHR13225:SF3 MISEXPRESSION SUPPRESSOR OF RAS 6 UPF0489 PROTEIN C5ORF22 HUMAN|HGNC=25603|UniProtKB=Q96AN5 Q96AN5 TMEM143 PTHR16095:SF10 TRANSMEMBRANE PROTEIN 143 FAMILY MEMBER TRANSMEMBRANE PROTEIN 143 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16118|UniProtKB=Q3SXZ7 Q3SXZ7 TTLL9 PTHR12241:SF39 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL9-RELATED cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=28962|UniProtKB=Q15005 Q15005 SPCS2 PTHR13085:SF3 MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 2 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;establishment of protein localization#GO:0045184;protein processing#GO:0016485;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;cellular protein metabolic process#GO:0044267;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to endoplasmic reticulum#GO:0070972;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;signal peptide processing#GO:0006465;cellular amide metabolic process#GO:0043603 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 HUMAN|HGNC=20678|UniProtKB=Q6X784 Q6X784 ZPBP2 PTHR15443:SF4 ZONA PELLUCIDA BINDING PROTEIN SP38 ZONA PELLUCIDA-BINDING PROTEIN 2 HUMAN|HGNC=619|UniProtKB=Q9BQE5 Q9BQE5 APOL2 PTHR14096:SF27 APOLIPOPROTEIN L APOLIPOPROTEIN L2 lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052 HUMAN|HGNC=17780|UniProtKB=Q562R1 Q562R1 ACTBL2 PTHR11937:SF168 ACTIN BETA-ACTIN-LIKE PROTEIN 2 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;enzyme binding#GO:0019899;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein kinase binding#GO:0019901;kinase binding#GO:0019900 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;localization of cell#GO:0051674;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;organelle organization#GO:0006996;chromosome organization#GO:0051276;ATP-dependent chromatin remodeling#GO:0043044;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;chromatin organization#GO:0006325;generation of neurons#GO:0048699;chromatin remodeling#GO:0006338;locomotion#GO:0040011 synapse#GO:0045202;histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell junction#GO:0030054;intracellular organelle lumen#GO:0070013;cell periphery#GO:0071944;membrane#GO:0016020;nuclear chromatin#GO:0000790;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;plasma membrane#GO:0005886 actin and actin related protein#PC00039 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 HUMAN|HGNC=23609|UniProtKB=Q9BXI6 Q9BXI6 TBC1D10A PTHR22957:SF215 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 10A GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=12536|UniProtKB=P22310 P22310 UGT1A4 PTHR48050:SF12 STEROL 3-BETA-GLUCOSYLTRANSFERASE UDP-GLUCURONOSYLTRANSFERASE 1A3-RELATED glycosyltransferase#PC00111 Nicotine degradation#P05914>UGT1A4#P05982 HUMAN|HGNC=28557|UniProtKB=Q8IXV7 Q8IXV7 KLHDC8B PTHR46260:SF2 RING-TYPE DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 8B HUMAN|HGNC=18464|UniProtKB=A4D2P6 A4D2P6 GRID2IP PTHR45725:SF3 FORMIN HOMOLOGY 2 FAMILY MEMBER DELPHILIN HUMAN|HGNC=14448|UniProtKB=Q7RTX1 Q7RTX1 TAS1R1 PTHR24061:SF3 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=12285|UniProtKB=A0A0A0MS01 A0A0A0MS01 TRGV10 PTHR19256:SF40 T-CELL RECEPTOR GAMMA CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=1553|UniProtKB=Q13185 Q13185 CBX3 PTHR22812:SF134 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 3 HUMAN|HGNC=12997|UniProtKB=Q96SZ4 Q96SZ4 ZSCAN10 PTHR24377:SF369 IP01015P-RELATED ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 10 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25397|UniProtKB=Q6MZP7 Q6MZP7 LIN54 PTHR12446:SF36 TESMIN/TSO1-RELATED PROTEIN LIN-54 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=29386|UniProtKB=Q5T0F9 Q5T0F9 CC2D1B PTHR13076:SF5 UNCHARACTERIZED COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=233|UniProtKB=Q08462 Q08462 ADCY2 PTHR45627:SF6 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 2 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Nicotine pharmacodynamics pathway#P06587>ADCY2#P06606;Opioid proopiomelanocortin pathway#P05917>AC#P06011;5HT4 type receptor mediated signaling pathway#P04376>AC#P04429;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;5HT1 type receptor mediated signaling pathway#P04373>AC#P04406;Beta2 adrenergic receptor signaling pathway#P04378>AC#P04446;Enkephalin release#P05913>AC#P05978;Opioid prodynorphin pathway#P05916>AC#P06001;Beta1 adrenergic receptor signaling pathway#P04377>AC#P04439;Beta3 adrenergic receptor signaling pathway#P04379>AC#P04450;Dopamine receptor mediated signaling pathway#P05912>AC#P05947;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841;Histamine H2 receptor mediated signaling pathway#P04386>AC#P04492;Opioid proenkephalin pathway#P05915>AC#P05993 HUMAN|HGNC=21655|UniProtKB=Q5SY68 Q5SY68 S100A7L2 PTHR11639:SF44 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A7-LIKE 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 calmodulin-related#PC00061 HUMAN|HGNC=16827|UniProtKB=O75794 O75794 CDC123 PTHR15323:SF6 D123 PROTEIN CELL DIVISION CYCLE PROTEIN 123 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=16669|UniProtKB=Q5DX21 Q5DX21 IGSF11 PTHR44699:SF1 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11 IMMUNOGLOBULIN SUPERFAMILY MEMBER 11 immunoglobulin#PC00123 HUMAN|HGNC=16452|UniProtKB=P0DN86 P0DN86 CGB8 PTHR11515:SF27 GLYCOPROTEIN HORMONE BETA CHAIN CHORIOGONADOTROPIN SUBUNIT BETA 3-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular#GO:0005622 peptide hormone#PC00179 HUMAN|HGNC=11731|UniProtKB=Q15569 Q15569 TESK1 PTHR46485:SF3 LIM DOMAIN KINASE 1 DUAL SPECIFICITY TESTIS-SPECIFIC PROTEIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;contractile actin filament bundle assembly#GO:0030038;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;actin filament-based process#GO:0030029;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;cellular component assembly#GO:0022607;stress fiber assembly#GO:0043149;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=2150|UniProtKB=Q16281 Q16281 CNGA3 PTHR45638:SF6 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL ALPHA-3 cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;inorganic molecular entity transmembrane transporter activity#GO:0015318;nucleotide binding#GO:0000166;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;purine nucleotide binding#GO:0017076;gated channel activity#GO:0022836;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 ligand-gated ion channel#PC00141 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 HUMAN|HGNC=29673|UniProtKB=Q13361 Q13361 MFAP5 PTHR16485:SF6 MICROFIBRILLAR-ASSOCIATED PROTEIN 2 MICROFIBRILLAR-ASSOCIATED PROTEIN 5 embryonic organ morphogenesis#GO:0048562;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;system development#GO:0048731;embryonic organ development#GO:0048568;embryo development#GO:0009790;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423;embryonic morphogenesis#GO:0048598 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;collagen-containing extracellular matrix#GO:0062023;extracellular region#GO:0005576 HUMAN|HGNC=23395|UniProtKB=Q9H2J1 Q9H2J1 ARRDC1-AS1 PTHR12138:SF120 PRIMATE-EXPANDED PROTEIN FAMILY CHROMOSOME 9 OPEN READING FRAME 37 HUMAN|HGNC=29269|UniProtKB=Q9P2E8 Q9P2E8 MARCHF4 PTHR46053:SF3 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF4 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=7956|UniProtKB=P25929 P25929 NPY1R PTHR24235:SF24 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 1 G-protein coupled receptor#PC00021 HUMAN|HGNC=122|UniProtKB=P24666 P24666 ACP1 PTHR11717:SF7 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195 HUMAN|HGNC=9959|UniProtKB=P51606 P51606 RENBP PTHR15108:SF0 N-ACYLGLUCOSAMINE-2-EPIMERASE N-ACYLGLUCOSAMINE 2-EPIMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 epimerase/racemase#PC00096 HUMAN|HGNC=23721|UniProtKB=Q7Z2W4 Q7Z2W4 ZC3HAV1 PTHR45740:SF8 POLY [ADP-RIBOSE] POLYMERASE ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1 HUMAN|HGNC=30775|UniProtKB=Q86UP8 Q86UP8 GTF2IRD2 PTHR47831:SF1 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2A-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 general transcription factor#PC00259 HUMAN|HGNC=6396|UniProtKB=O00505 O00505 KPNA3 PTHR23316:SF6 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-4 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=25996|UniProtKB=Q6P6C2 Q6P6C2 ALKBH5 PTHR32074:SF2 RNA DEMETHYLASE ALKBH5 RNA DEMETHYLASE ALKBH5 catalytic activity, acting on RNA#GO:0140098;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;transport#GO:0006810;RNA processing#GO:0006396;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;oxidation-reduction process#GO:0055114;protein export from nucleus#GO:0006611;demethylation#GO:0070988;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;heterocycle metabolic process#GO:0046483;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;mRNA transport#GO:0051028;ribonucleoprotein complex localization#GO:0071166;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;oxidative demethylation#GO:0070989;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;mRNA processing#GO:0006397;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA processing factor#PC00147 HUMAN|HGNC=29082|UniProtKB=O60347 O60347 TBC1D12 PTHR22957:SF467 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 12 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;nucleoside-triphosphatase activity#GO:0017111 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of autophagosome assembly#GO:2000785;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;amide transport#GO:0042886;organic substance transport#GO:0071702;vacuole organization#GO:0007033;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;macromolecule metabolic process#GO:0043170;regulation of GTPase activity#GO:0043087;regulation of organelle organization#GO:0033043;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of macroautophagy#GO:0016241;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;peptide transport#GO:0015833;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;autophagosome#GO:0005776;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 HUMAN|HGNC=26942|UniProtKB=Q9NZZ3 Q9NZZ3 CHMP5 PTHR22761:SF85 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 5 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=12554|UniProtKB=P16662 P16662 UGT2B7 PTHR48043:SF87 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2B7 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 Nicotine degradation#P05914>UGT2B7#P05980 HUMAN|HGNC=9262|UniProtKB=Q9H2H8 Q9H2H8 PPIL3 PTHR45625:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 chaperone#PC00072 HUMAN|HGNC=24844|UniProtKB=Q8N7S2 Q8N7S2 DNAJC5G PTHR44027:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5G chaperone#PC00072 HUMAN|HGNC=28431|UniProtKB=Q8N2G4 Q8N2G4 LYPD1 PTHR10036:SF7 CD59 GLYCOPROTEIN LY6/PLAUR DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;receptor regulator activity#GO:0030545;binding#GO:0005488;acetylcholine receptor activity#GO:0015464;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;acetylcholine receptor regulator activity#GO:0030548;acetylcholine binding#GO:0042166;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267 HUMAN|HGNC=15998|UniProtKB=Q8IVL0 Q8IVL0 NAV3 PTHR12784:SF18 STEERIN NEURON NAVIGATOR 3 system development#GO:0048731;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 HUMAN|HGNC=30266|UniProtKB=Q96NA2 Q96NA2 RILP PTHR21502:SF7 ZINC FINGER PROTEIN DZIP1 RAB-INTERACTING LYSOSOMAL PROTEIN vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=29150|UniProtKB=Q9Y2E4 Q9Y2E4 DIP2C PTHR22754:SF33 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG C HUMAN|HGNC=18641|UniProtKB=Q8IX01 Q8IX01 SUGP2 PTHR23340:SF2 ARGININE/SERINE RICH SPLICING FACTOR SF4/14 SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 2 RNA splicing factor#PC00148 HUMAN|HGNC=16826|UniProtKB=Q15714 Q15714 TSC22D1 PTHR46745:SF1 TSC22 DOMAIN FAMILY PROTEIN 1 TSC22 DOMAIN FAMILY PROTEIN 1 HUMAN|HGNC=32690|UniProtKB=Q8NEG7 Q8NEG7 DENND6B PTHR13677:SF2 UNCHARACTERIZED PROTEIN DENND6B Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=12270|UniProtKB=Q9BQ50 Q9BQ50 TREX2 PTHR13058:SF24 THREE PRIME REPAIR EXONUCLEASE 1, 2 THREE PRIME REPAIR EXONUCLEASE 2 3'-5'-exodeoxyribonuclease activity#GO:0008296;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;exodeoxyribonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;exodeoxyribonuclease activity, producing 5'-phosphomonoesters#GO:0016895;deoxyribonuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 HUMAN|HGNC=8549|UniProtKB=Q9UL45 Q9UL45 BLOC1S6 PTHR31328:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 localization#GO:0051179;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;BLOC-1 complex#GO:0031083;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;plasma membrane#GO:0005886 HUMAN|HGNC=4021|UniProtKB=Q06136 Q06136 KDSR PTHR43550:SF3 3-KETODIHYDROSPHINGOSINE REDUCTASE 3-KETODIHYDROSPHINGOSINE REDUCTASE reductase#PC00198 HUMAN|HGNC=26398|UniProtKB=Q96NN9 Q96NN9 AIFM3 PTHR43557:SF8 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 3 oxidoreductase#PC00176 HUMAN|HGNC=2047|UniProtKB=O00501 O00501 CLDN5 PTHR12002:SF35 CLAUDIN CLAUDIN-5 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=17499|UniProtKB=Q9UGK8 Q9UGK8 SERGEF PTHR45622:SF40 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HECTD2-RELATED ubiquitin-protein ligase#PC00234 EGF receptor signaling pathway#P00018>RKIP#P00548;Ubiquitin proteasome pathway#P00060>E3#P01490 HUMAN|HGNC=15887|UniProtKB=Q9BX40 Q9BX40 LSM14B PTHR13586:SF1 SCD6 PROTEIN-RELATED PROTEIN LSM14 HOMOLOG B nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoplasmic mRNA processing body assembly#GO:0033962;cellular process#GO:0009987 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 HUMAN|HGNC=10729|UniProtKB=Q9H3S1 Q9H3S1 SEMA4A PTHR11036:SF15 SEMAPHORIN SEMAPHORIN-4A receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=6608|UniProtKB=Q8NHJ6 Q8NHJ6 LILRB4 PTHR11738:SF178 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 4 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=5971|UniProtKB=P42701 P42701 IL12RB1 PTHR23036:SF51 CYTOKINE RECEPTOR INTERLEUKIN-12 RECEPTOR SUBUNIT BETA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;cytokine binding#GO:0019955 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of receptor signaling pathway via STAT#GO:1904894;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;tyrosine phosphorylation of STAT protein#GO:0007260;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;peptidyl-tyrosine modification#GO:0018212;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 HUMAN|HGNC=1442|UniProtKB=P0DP23 P0DP23 CALM1 PTHR23050:SF427 CALCIUM BINDING PROTEIN CALMODULIN-1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;CCKR signaling map#P06959>CaM#P07193;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 HUMAN|HGNC=12744|UniProtKB=Q9NP71 Q9NP71 MLXIPL PTHR15741:SF14 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR CARBOHYDRATE-RESPONSIVE ELEMENT-BINDING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=11780|UniProtKB=P49221 P49221 TGM4 PTHR11590:SF70 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 4 transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular protein modification process#GO:0006464 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular region#GO:0005576 transferase#PC00220 HUMAN|HGNC=23231|UniProtKB=Q96SA4 Q96SA4 SERINC2 PTHR10383:SF22 SERINE INCORPORATOR SERINE INCORPORATOR 2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 HUMAN|HGNC=843|UniProtKB=P48201 P48201 ATP5MC3 PTHR10031:SF30 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C3, MITOCHONDRIAL cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide biosynthetic process#GO:0009152 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 HUMAN|HGNC=6896|UniProtKB=Q9P0L2 Q9P0L2 MARK1 PTHR24346:SF21 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE/THREONINE-PROTEIN KINASE MARK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=2154|UniProtKB=Q9H4B4 Q9H4B4 PLK3 PTHR24345:SF42 SERINE/THREONINE-PROTEIN KINASE PLK SERINE/THREONINE-PROTEIN KINASE PLK3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;cell division#GO:0051301;mitotic cell cycle phase transition#GO:0044772;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;endomembrane system organization#GO:0010256;negative regulation of cell cycle process#GO:0010948;regulation of cell division#GO:0051302;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;mitotic cell cycle#GO:0000278;cellular component disassembly#GO:0022411;mitotic nuclear division#GO:0140014;regulation of G1/S transition of mitotic cell cycle#GO:2000045;cytokinesis#GO:0000910;regulation of cytokinesis#GO:0032465;negative regulation of cellular process#GO:0048523;negative regulation of G1/S transition of mitotic cell cycle#GO:2000134;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;membrane fission#GO:0090148;Golgi organization#GO:0007030;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;organelle disassembly#GO:1903008;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G1/S phase transition#GO:1902806 spindle pole#GO:0000922;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=5044|UniProtKB=P61978 P61978 HNRNPK PTHR10288:SF307 KH DOMAIN CONTAINING RNA BINDING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=22939|UniProtKB=Q86W24 Q86W24 NLRP14 PTHR45690:SF2 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 14 HUMAN|HGNC=10968|UniProtKB=Q9H015 Q9H015 SLC22A4 PTHR24064:SF222 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 4 ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;establishment of localization#GO:0051234;organic cation transport#GO:0015695;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;cation transport#GO:0006812 secondary carrier transporter#PC00258 HUMAN|Ensembl=ENSG00000283776|UniProtKB=A0A1W2PPH5 A0A1W2PPH5 TAF11L13 PTHR13218:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TAFII28 DOMAIN-CONTAINING PROTEIN transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=8471|UniProtKB=Q96RD0 Q96RD0 OR8B2 PTHR48018:SF61 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=28061|UniProtKB=Q6NXP0 Q6NXP0 EFCAB12 PTHR47225:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 12 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 12 calmodulin-related#PC00061 HUMAN|HGNC=16855|UniProtKB=Q15035 Q15035 TRAM2 PTHR12371:SF4 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 2 cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=10446|UniProtKB=P55042 P55042 RRAD PTHR45775:SF3 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN RAD carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;transporter activity#GO:0005215;channel activity#GO:0015267;calcium channel regulator activity#GO:0005246;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;channel regulator activity#GO:0016247;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=30365|UniProtKB=Q7L5Y1 Q7L5Y1 ENOSF1 PTHR13794:SF58 ENOLASE SUPERFAMILY, MANDELATE RACEMASE MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 cation binding#GO:0043169;carbon-oxygen lyase activity#GO:0016835;magnesium ion binding#GO:0000287;binding#GO:0005488;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;metal ion binding#GO:0046872;lyase activity#GO:0016829;ion binding#GO:0043167 carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 epimerase/racemase#PC00096 HUMAN|HGNC=23711|UniProtKB=Q6NUK4 Q6NUK4 REEP3 PTHR12300:SF39 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;cytoplasmic microtubule#GO:0005881;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;microtubule#GO:0005874;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 HUMAN|HGNC=26763|UniProtKB=Q2M3C6 Q2M3C6 TMEM266 PTHR46842:SF1 TRANSMEMBRANE PROTEIN 266 TRANSMEMBRANE PROTEIN 266 HUMAN|HGNC=118|UniProtKB=Q99798 Q99798 ACO2 PTHR43160:SF6 ACONITATE HYDRATASE B ACONITATE HYDRATASE, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;4 iron, 4 sulfur cluster binding#GO:0051539;metal cluster binding#GO:0051540;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 hydratase#PC00120 TCA cycle#P00051>Aconitase#P01268 HUMAN|HGNC=29102|UniProtKB=A0JNW5 A0JNW5 UHRF1BP1L PTHR22774:SF17 UNCHARACTERIZED UHRF1-BINDING PROTEIN 1-LIKE HUMAN|HGNC=3301|UniProtKB=Q9GZV4 Q9GZV4 EIF5A2 PTHR11673:SF13 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-2 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;positive regulation of cellular protein metabolic process#GO:0032270;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 translation initiation factor#PC00224 HUMAN|HGNC=21558|UniProtKB=Q5TD94 Q5TD94 RSPH4A PTHR13159:SF4 RADIAL SPOKEHEAD-RELATED RADIAL SPOKE HEAD PROTEIN 4 HOMOLOG A vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=1665|UniProtKB=Q14108 Q14108 SCARB2 PTHR11923:SF92 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 LYSOSOME MEMBRANE PROTEIN 2 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=24591|UniProtKB=Q6UXB4 Q6UXB4 CLEC4G PTHR22802:SF245 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER G membrane traffic protein#PC00150 HUMAN|HGNC=20668|UniProtKB=P59942 P59942 MCCD1 PTHR37877:SF1 MITOCHONDRIAL COILED-COIL DOMAIN PROTEIN 1 MITOCHONDRIAL COILED-COIL DOMAIN PROTEIN 1 HUMAN|HGNC=34416|UniProtKB=P0C263 P0C263 SBK2 PTHR48013:SF7 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED SERINE/THREONINE-PROTEIN KINASE SBK2 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of JNK cascade#GO:0046330;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;positive regulation of protein serine/threonine kinase activity#GO:0071902;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=12626|UniProtKB=Q9Y6I4 Q9Y6I4 USP3 PTHR21646:SF19 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=10798|UniProtKB=Q8IWL2 Q8IWL2 SFTPA1 PTHR24024:SF13 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A PULMONARY SURFACTANT-ASSOCIATED PROTEIN A1-RELATED endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;rough endoplasmic reticulum#GO:0005791;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;late endosome#GO:0005770;plasma membrane#GO:0005886 surfactant#PC00212 HUMAN|HGNC=17813|UniProtKB=Q969P0 Q969P0 IGSF8 PTHR12207:SF22 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 8 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=20480|UniProtKB=Q96PP9 Q96PP9 GBP4 PTHR10751:SF17 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 4 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830 heterotrimeric G-protein#PC00117 HUMAN|HGNC=9055|UniProtKB=Q00722 Q00722 PLCB2 PTHR10336:SF10 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-2 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Endogenous cannabinoid signaling#P05730>PLC#P05746;Endothelin signaling pathway#P00019>PLCbeta#P00591;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484 HUMAN|HGNC=4329|UniProtKB=P48167 P48167 GLRB PTHR18945:SF29 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT BETA signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;transport#GO:0006810;system process#GO:0003008;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;regulation of biological process#GO:0050789;inorganic anion transmembrane transport#GO:0098661;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;signaling#GO:0023052;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=1641|UniProtKB=Q9NNX6 Q9NNX6 CD209 PTHR22802:SF197 C-TYPE LECTIN SUPERFAMILY MEMBER CD209 ANTIGEN membrane traffic protein#PC00150 HUMAN|HGNC=1961|UniProtKB=P11230 P11230 CHRNB1 PTHR18945:SF477 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=27379|UniProtKB=Q8IUW5 Q8IUW5 RELL1 PTHR31037:SF1 RELT-LIKE PROTEIN 1-RELATED RELT-LIKE PROTEIN 1 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;regulation of stress-activated MAPK cascade#GO:0032872;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=175|UniProtKB=P37023 P37023 ACVRL1 PTHR23255:SF66 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II SERINE/THREONINE-PROTEIN KINASE RECEPTOR R3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 heart development#GO:0007507;signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;developmental process#GO:0032502;protein modification process#GO:0036211;transforming growth factor beta receptor signaling pathway#GO:0007179;phosphorus metabolic process#GO:0006793;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;blood vessel morphogenesis#GO:0048514;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;tube development#GO:0035295;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;angiogenesis#GO:0001525;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 HUMAN|HGNC=2172|UniProtKB=Q02246 Q02246 CNTN2 PTHR10075:SF55 BASIGIN RELATED CONTACTIN-2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=4130|UniProtKB=Q9NY28 Q9NY28 GALNT8 PTHR11675:SF50 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 8-RELATED cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=12122|UniProtKB=A0A0B4J276 A0A0B4J276 TRAV25 PTHR19433:SF80 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 25 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=5542|UniProtKB=P38935 P38935 IGHMBP2 PTHR43788:SF8 DNA2/NAM7 HELICASE FAMILY MEMBER DNA-BINDING PROTEIN SMUBP-2 DNA metabolism protein#PC00009 HUMAN|HGNC=17268|UniProtKB=Q9H3R5 Q9H3R5 CENPH PTHR48122:SF1 CENTROMERE PROTEIN H CENTROMERE PROTEIN H HUMAN|HGNC=9176|UniProtKB=P49005 P49005 POLD2 PTHR10416:SF0 DNA POLYMERASE DELTA SUBUNIT 2 DNA POLYMERASE DELTA SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;DNA biosynthetic process#GO:0071897;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;DNA strand elongation involved in DNA replication#GO:0006271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 DNA polymerase complex#GO:0042575;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>Pol delta#P00533 HUMAN|HGNC=23790|UniProtKB=Q96FX7 Q96FX7 TRMT61A PTHR12133:SF2 TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRMT61A tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA (adenine) methyltransferase activity#GO:0016426;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 RNA methyltransferase#PC00033 HUMAN|HGNC=26411|UniProtKB=Q7Z353 Q7Z353 HDX PTHR11636:SF80 POU DOMAIN HIGHLY DIVERGENT HOMEOBOX cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=25763|UniProtKB=Q9H0W8 Q9H0W8 SMG9 PTHR14270:SF0 UNCHARACTERIZED PROTEIN SMG9 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 HUMAN|HGNC=2207|UniProtKB=P29400 P29400 COL4A5 PTHR24023:SF1029 COLLAGEN ALPHA COLLAGEN ALPHA-5(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=8487|UniProtKB=Q13415 Q13415 ORC1 PTHR10763:SF23 CELL DIVISION CONTROL PROTEIN 6-RELATED ORIGIN RECOGNITION COMPLEX SUBUNIT 1 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;mitotic DNA integrity checkpoint#GO:0044774;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;aromatic compound biosynthetic process#GO:0019438;DNA replication initiation#GO:0006270;cell cycle G2/M phase transition#GO:0044839;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;mitotic cell cycle phase transition#GO:0044772;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;mitotic DNA replication checkpoint#GO:0033314;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;mitotic cell cycle checkpoint#GO:0007093;macromolecule biosynthetic process#GO:0009059;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;DNA-dependent DNA replication#GO:0006261;negative regulation of mitotic cell cycle#GO:0045930;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;DNA replication checkpoint#GO:0000076;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;DNA replication#GO:0006260;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;nuclear chromosome, telomeric region#GO:0000784;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular#GO:0005622;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 replication origin binding protein#PC00199 HUMAN|HGNC=6775|UniProtKB=O95405 O95405 ZFYVE9 PTHR46319:SF2 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 9 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 TGF-beta signaling pathway#P00052>SARA#P01281 HUMAN|HGNC=26543|UniProtKB=Q96M60 Q96M60 FAM227B PTHR33560:SF2 PROTEIN FAM227B PROTEIN FAM227B HUMAN|HGNC=26941|UniProtKB=Q9Y3C8 Q9Y3C8 UFC1 PTHR12921:SF0 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=25305|UniProtKB=Q9H0G5 Q9H0G5 NSRP1 PTHR31938:SF4 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HUMAN|HGNC=30296|UniProtKB=Q8IY67 Q8IY67 RAVER1 PTHR23189:SF46 RNA RECOGNITION MOTIF-CONTAINING RIBONUCLEOPROTEIN PTB-BINDING 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=14163|UniProtKB=Q9H0X4 Q9H0X4 FAM234A PTHR21419:SF7 FAMILY NOT NAMED PROTEIN FAM234A HUMAN|HGNC=16781|UniProtKB=Q9BXD5 Q9BXD5 NPL PTHR12128:SF21 DIHYDRODIPICOLINATE SYNTHASE N-ACETYLNEURAMINATE LYASE lyase#PC00144 N-acetylglucosamine metabolism#P02756>N-acetylneuraminate lyase#P03040 HUMAN|HGNC=17634|UniProtKB=Q7Z417 Q7Z417 NUFIP2 PTHR28333:SF2 NUCLEAR FRAGILE X MENTAL RETARDATION-INTERACTING PROTEIN 2 NUCLEAR FRAGILE X MENTAL RETARDATION-INTERACTING PROTEIN 2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoplasmic stress granule#GO:0010494;polysome#GO:0005844;ribosome#GO:0005840 HUMAN|HGNC=6714|UniProtKB=Q14766 Q14766 LTBP1 PTHR24034:SF140 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 1 extracellular matrix structural protein#PC00103 HUMAN|HGNC=3180|UniProtKB=P24530 P24530 EDNRB PTHR46099:SF3 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ENDOTHELIN RECEPTOR TYPE B Endothelin signaling pathway#P00019>ET-RA/B#P00580 HUMAN|HGNC=16501|UniProtKB=P50479 P50479 PDLIM4 PTHR24214:SF6 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=11389|UniProtKB=Q15831 Q15831 STK11 PTHR43895:SF25 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED SERINE/THREONINE-PROTEIN KINASE STK11 p53 pathway by glucose deprivation#P04397>LKB1#P04647 HUMAN|HGNC=11338|UniProtKB=O60224 O60224 SSX4B PTHR14112:SF8 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX4 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=37057|UniProtKB=Q8NAP8 Q8NAP8 ZBTB8B PTHR24414:SF26 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 8B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=29909|UniProtKB=Q96AB6 Q96AB6 NTAN1 PTHR12498:SF0 N-TERMINAL ASPARAGINE AMIDOHYDROLASE PROTEIN N-TERMINAL ASPARAGINE AMIDOHYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 protein modifying enzyme#PC00260 HUMAN|HGNC=1722|UniProtKB=P06493 P06493 CDK1 PTHR24056:SF334 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 1 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 nuclear division#GO:0000280;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;mitotic DNA integrity checkpoint#GO:0044774;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;cellular response to stress#GO:0033554;cell cycle G2/M phase transition#GO:0044839;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;G2 DNA damage checkpoint#GO:0031572;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;mitotic DNA damage checkpoint#GO:0044773;organonitrogen compound metabolic process#GO:1901564;negative regulation of mitotic cell cycle#GO:0045930;protein phosphorylation#GO:0006468;cellular process#GO:0009987;response to stimulus#GO:0050896;organelle organization#GO:0006996;mitotic G2 DNA damage checkpoint#GO:0007095;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;cell cycle#GO:0007049;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>Cdc2#P04634 HUMAN|HGNC=18926|UniProtKB=Q3LI77 Q3LI77 KRTAP13-4 PTHR19051:SF31 KERATIN-ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 13-4 structural protein#PC00211 HUMAN|HGNC=6906|UniProtKB=P42679 P42679 MATK PTHR24418:SF399 TYROSINE-PROTEIN KINASE MEGAKARYOCYTE-ASSOCIATED TYROSINE-PROTEIN KINASE protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 HUMAN|HGNC=28236|UniProtKB=Q5T5S1 Q5T5S1 CCDC183 PTHR47115:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 183 COILED-COIL DOMAIN-CONTAINING PROTEIN 183 HUMAN|HGNC=29175|UniProtKB=Q8N5D0 Q8N5D0 WDTC1 PTHR15574:SF40 WD REPEAT DOMAIN-CONTAINING FAMILY WD AND TETRATRICOPEPTIDE REPEATS PROTEIN 1 lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of lipid biosynthetic process#GO:0046890;negative regulation of cellular process#GO:0048523;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;negative regulation of biosynthetic process#GO:0009890;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;fatty acid metabolic process#GO:0006631;regulation of cellular biosynthetic process#GO:0031326;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=21205|UniProtKB=Q96FE5 Q96FE5 LINGO1 PTHR24373:SF31 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 1 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=1500|UniProtKB=Q92851 Q92851 CASP10 PTHR10454:SF26 CASPASE CASPASE-10 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of cellular protein metabolic process#GO:0032270;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;positive regulation of cell death#GO:0010942;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 Apoptosis signaling pathway#P00006>Caspase 10#P00295;FAS signaling pathway#P00020>Pro-Caspase10#P00598;FAS signaling pathway#P00020>Caspase10#P00606 HUMAN|HGNC=22960|UniProtKB=Q8NBQ5 Q8NBQ5 HSD17B11 PTHR24322:SF489 PKSB ESTRADIOL 17-BETA-DEHYDROGENASE 11 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=16839|UniProtKB=Q5TEJ8 Q5TEJ8 THEMIS2 PTHR15215:SF2 CABIT DOMAIN-CONTAINING PROTEIN PROTEIN THEMIS2 antigen receptor-mediated signaling pathway#GO:0050851;immune response-regulating signaling pathway#GO:0002764;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;activation of immune response#GO:0002253;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;positive regulation of biological process#GO:0048518;T cell receptor signaling pathway#GO:0050852 HUMAN|HGNC=12181|UniProtKB=A0A584 A0A584 TRBV11-2 PTHR23268:SF47 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 11-2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=11120|UniProtKB=P17405 P17405 SMPD1 PTHR10340:SF34 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE phosphodiesterase#PC00185 HUMAN|HGNC=18142|UniProtKB=Q9Y4D1 Q9Y4D1 DAAM1 PTHR45725:SF16 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 1 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856 HUMAN|HGNC=8697|UniProtKB=Q9Y5H3 Q9Y5H3 PCDHGA10 PTHR24028:SF110 CADHERIN-87A PROTOCADHERIN GAMMA-A10 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=25014|UniProtKB=Q9P000 Q9P000 COMMD9 PTHR15663:SF4 COMM DOMAIN-CONTAINING PROTEIN 9 COMM DOMAIN-CONTAINING PROTEIN 9 HUMAN|HGNC=16518|UniProtKB=Q5TA82 Q5TA82 LCE2D PTHR23263:SF132 SMALL PROLINE-RICH PROTEIN LATE CORNIFIED ENVELOPE PROTEIN 2A-RELATED HUMAN|HGNC=41911|UniProtKB=Q6ZU69 Q6ZU69 FAM205A PTHR21859:SF15 ACROSOME-SPECIFIC PROTEIN PROTEIN FAM205A-RELATED HUMAN|HGNC=9029|UniProtKB=O15496 O15496 PLA2G10 PTHR11716:SF4 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP 10 SECRETORY PHOSPHOLIPASE A2 phospholipase#PC00186 HUMAN|HGNC=10840|UniProtKB=P29353 P29353 SHC1 PTHR10337:SF2 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>p52 SHC1#P07151;CCKR signaling map#P06959>p66 SHC1#P07168;CCKR signaling map#P06959>SHC1 @EGFR#P07083;FGF signaling pathway#P00021>Shc#P00639;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Shc#P00865;EGF receptor signaling pathway#P00018>Shc#P00554;Interleukin signaling pathway#P00036>Shc#P00997;PDGF signaling pathway#P00047>Shc#P01175;Angiogenesis#P00005>Shc#P00183;CCKR signaling map#P06959>SHC1#P07138;Ras Pathway#P04393>Shc#P04579;CCKR signaling map#P06959>p46 SHC1#P07098;Integrin signalling pathway#P00034>Shc#P00949 HUMAN|HGNC=4184|UniProtKB=Q9H0R5 Q9H0R5 GBP3 PTHR10751:SF96 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 3 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 heterotrimeric G-protein#PC00117 HUMAN|HGNC=9955|UniProtKB=Q04206 Q04206 RELA PTHR24169:SF1 NUCLEAR FACTOR NF-KAPPA-B PROTEIN TRANSCRIPTION FACTOR P65 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to external biotic stimulus#GO:0043207;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;innate immune response#GO:0045087;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;inflammatory response#GO:0006954;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;NIK/NF-kappaB signaling#GO:0038061;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Gonadotropin-releasing hormone receptor pathway#P06664>p65#P06702;Toll receptor signaling pathway#P00054>NFkappaB#P01354;Apoptosis signaling pathway#P00006>NFkappaB#P00297 HUMAN|HGNC=3009|UniProtKB=P27487 P27487 DPP4 PTHR11731:SF128 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 4 serine protease#PC00203 HUMAN|Ensembl=ENSG00000285496|UniProtKB=A0A126GWI2 A0A126GWI2 OR2A25 PTHR26453:SF257 OLFACTORY RECEPTOR OLFACTORY RECEPTOR transmembrane signal receptor#PC00197 HUMAN|HGNC=8579|UniProtKB=Q99487 Q99487 PAFAH2 PTHR10272:SF6 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE 2, CYTOPLASMIC carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 protein modifying enzyme#PC00260 HUMAN|HGNC=31789|UniProtKB=Q4VNC0 Q4VNC0 ATP13A5 PTHR45630:SF4 CATION-TRANSPORTING ATPASE-RELATED CATION-TRANSPORTING ATPASE 13A5-RELATED cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 HUMAN|HGNC=17362|UniProtKB=Q14865 Q14865 ARID5B PTHR13964:SF37 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=1939|UniProtKB=O00533 O00533 CHL1 PTHR12231:SF257 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN NEURAL CELL ADHESION MOLECULE L1-LIKE PROTEIN HUMAN|HGNC=1564|UniProtKB=Q16773 Q16773 KYAT1 PTHR43807:SF14 FI04487P KYNURENINE--OXOGLUTARATE TRANSAMINASE 1 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transaminase#PC00216 HUMAN|HGNC=5363|UniProtKB=P47928 P47928 ID4 PTHR11723:SF6 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-4 molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=16713|UniProtKB=O75494 O75494 SRSF10 PTHR23147:SF5 SERINE/ARGININE RICH SPLICING FACTOR SERINE/ARGININE-RICH SPLICING FACTOR 10 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=30130|UniProtKB=Q6TCH7 Q6TCH7 PAQR3 PTHR20855:SF15 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021 HUMAN|HGNC=5112|UniProtKB=Q92826 Q92826 HOXB13 PTHR45804:SF6 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-B13 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=15829|UniProtKB=Q9H5J4 Q9H5J4 ELOVL6 PTHR11157:SF125 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=28650|UniProtKB=Q8IYX0 Q8IYX0 ZNF679 PTHR24384:SF179 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 679 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=15511|UniProtKB=Q9ULK5 Q9ULK5 VANGL2 PTHR20886:SF10 VANG-LIKE PROTEIN VANG-LIKE PROTEIN 2 signal transduction#GO:0007165;regulation of anatomical structure morphogenesis#GO:0022603;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;non-canonical Wnt signaling pathway#GO:0035567;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;establishment of planar polarity#GO:0001736;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;tissue development#GO:0009888;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;biological regulation#GO:0065007;morphogenesis of an epithelium#GO:0002009;multicellular organismal process#GO:0032501 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=4370|UniProtKB=Q9Y692 Q9Y692 GMEB1 PTHR10417:SF3 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=13168|UniProtKB=Q03936 Q03936 ZNF92 PTHR24384:SF211 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 138-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=4373|UniProtKB=P60983 P60983 GMFB PTHR11249:SF3 GLIAL FACTOR NATURATION FACTOR GLIA MATURATION FACTOR BETA protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cortical patch#GO:0030479;organelle#GO:0043226;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207 HUMAN|HGNC=10639|UniProtKB=O43927 O43927 CXCL13 PTHR10179:SF27 CXC CHEMOKINE C-X-C MOTIF CHEMOKINE 13 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=6293|UniProtKB=O15554 O15554 KCNN4 PTHR10153:SF41 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL INTERMEDIATE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;calmodulin binding#GO:0005516;transporter activity#GO:0005215;channel activity#GO:0015267;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=3315|UniProtKB=P26378 P26378 ELAVL4 PTHR10352:SF9 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 4 translation initiation factor#PC00224 HUMAN|HGNC=26595|UniProtKB=Q8N584 Q8N584 TTC39C PTHR31859:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39C HUMAN|HGNC=27733|UniProtKB=Q6ZVF9 Q6ZVF9 GPRIN3 PTHR15718:SF6 UNCHARACTERIZED G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 3 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=10867|UniProtKB=Q9UJ37 Q9UJ37 ST6GALNAC2 PTHR45941:SF5 FAMILY NOT NAMED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 2 HUMAN|HGNC=2365|UniProtKB=Q14194 Q14194 CRMP1 PTHR11647:SF54 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339 HUMAN|HGNC=17198|UniProtKB=Q86X52 Q86X52 CHSY1 PTHR12369:SF42 CHONDROITIN SYNTHASE CHONDROITIN SULFATE SYNTHASE 1 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;chondroitin sulfate metabolic process#GO:0030204;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;proteoglycan metabolic process#GO:0006029;chondroitin sulfate proteoglycan metabolic process#GO:0050654;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;glycosaminoglycan biosynthetic process#GO:0006024;small molecule metabolic process#GO:0044281 glycosyltransferase#PC00111 HUMAN|HGNC=8525|UniProtKB=O14753 O14753 OVOL1 PTHR10032:SF217 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS TRANSCRIPTION FACTOR OVO-LIKE 1-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;epithelium development#GO:0060429;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;epidermis development#GO:0008544;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;epidermal cell differentiation#GO:0009913;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=34491|UniProtKB=Q6ZSJ9 Q6ZSJ9 SHISA6 PTHR31774:SF0 PROTEIN SHISA-9-RELATED PROTEIN SHISA-6 signal transduction#GO:0007165;regulation of neurotransmitter receptor activity#GO:0099601;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;ionotropic glutamate receptor signaling pathway#GO:0035235;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of AMPA receptor activity#GO:2000311;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;ion transmembrane transport#GO:0034220;regulation of synaptic plasticity#GO:0048167;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of signaling receptor activity#GO:0010469;response to stimulus#GO:0050896;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of trans-synaptic signaling#GO:0099177 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;leading edge membrane#GO:0031256;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;ion channel complex#GO:0034702;cell junction#GO:0030054;cell projection membrane#GO:0031253;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 HUMAN|HGNC=7105|UniProtKB=O75030 O75030 MITF PTHR45776:SF4 MIP04163P MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16897|UniProtKB=P52758 P52758 RIDA PTHR11803:SF53 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 deaminase#PC00088 HUMAN|HGNC=15308|UniProtKB=Q8N162 Q8N162 OR8H2 PTHR48018:SF175 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8H2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=14060|UniProtKB=Q9UBZ9 Q9UBZ9 REV1 PTHR45990:SF1 DNA REPAIR PROTEIN REV1 DNA REPAIR PROTEIN REV1 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;DNA polymerase activity#GO:0034061;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 HUMAN|HGNC=4387|UniProtKB=P08754 P08754 GNAI3 PTHR10218:SF230 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 Nicotine pharmacodynamics pathway#P06587>GNAI#P06609;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Endogenous cannabinoid signaling#P05730>Galpha#P05751;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid prodynorphin pathway#P05916>G-protein#P06002;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proenkephalin pathway#P05915>G-protein#P05994;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873 HUMAN|HGNC=7985|UniProtKB=Q15406 Q15406 NR6A1 PTHR48092:SF18 KNIRPS-RELATED PROTEIN-RELATED NUCLEAR RECEPTOR SUBFAMILY 6 GROUP A MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=17811|UniProtKB=Q8IY63 Q8IY63 AMOTL1 PTHR14826:SF12 ANGIOMOTIN ANGIOMOTIN-LIKE PROTEIN 1 establishment or maintenance of cell polarity#GO:0007163;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;developmental process#GO:0032502;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;system development#GO:0048731;establishment of cell polarity#GO:0030010;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of cellular component movement#GO:0051270;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;regulation of cell motility#GO:2000145;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;tube development#GO:0035295;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;hippo signaling#GO:0035329;angiogenesis#GO:0001525;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 intracellular vesicle#GO:0097708;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;apical junction complex#GO:0043296;plasma membrane#GO:0005886 HUMAN|HGNC=4593|UniProtKB=Q13255 Q13255 GRM1 PTHR24060:SF29 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 1 amino acid binding#GO:0016597;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888;glutamate receptor activity#GO:0008066;postsynaptic neurotransmitter receptor activity#GO:0098960;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;ion binding#GO:0043167;anion binding#GO:0043168;organic acid binding#GO:0043177;glutamate binding#GO:0016595 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;intrinsic component of membrane#GO:0031224;postsynaptic density membrane#GO:0098839;integral component of plasma membrane#GO:0005887;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Metabotropic glutamate receptor group III pathway#P00039>mGluR 1/5#P01040;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Endogenous cannabinoid signaling#P05730>mGluR#P05748;Metabotropic glutamate receptor group I pathway#P00041>mGluR1#P01062;Metabotropic glutamate receptor group I pathway#P00041>mGluR5#P01061;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=546|UniProtKB=P13928 P13928 ANXA8 PTHR10502:SF133 ANNEXIN ANNEXIN A8-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;endosomal transport#GO:0016197;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of lipase activity#GO:0060191;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of phospholipase activity#GO:0010517;endomembrane system organization#GO:0010256;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;endosome organization#GO:0007032;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;vesicle organization#GO:0016050;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of endopeptidase activity#GO:0052548;intracellular transport#GO:0046907;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calcium-binding protein#PC00060 HUMAN|HGNC=29322|UniProtKB=Q9HCG8 Q9HCG8 CWC22 PTHR18034:SF3 CELL CYCLE CONTROL PROTEIN CWF22-RELATED PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA processing factor#PC00147 HUMAN|HGNC=12517|UniProtKB=P25874 P25874 UCP1 PTHR45618:SF19 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL BROWN FAT UNCOUPLING PROTEIN 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to stress#GO:0006950;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;response to cold#GO:0009409;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152 secondary carrier transporter#PC00258 HUMAN|HGNC=13014|UniProtKB=Q9UK13 Q9UK13 ZNF221 PTHR24388:SF36 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 221-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=18417|UniProtKB=O75409 O75409 H2AP PTHR23430:SF63 HISTONE H2A HUNTINGTIN-INTERACTING PROTEIN M heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=24160|UniProtKB=Q3B7T3 Q3B7T3 BEAN1 PTHR36464:SF1 PROTEIN BEAN1 PROTEIN BEAN1 HUMAN|HGNC=14154|UniProtKB=Q96S06 Q96S06 LMF1 PTHR14463:SF10 LIPASE MATURATION FACTOR LIPASE MATURATION FACTOR 1 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;protein maturation#GO:0051604;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=7381|UniProtKB=Q04912 Q04912 MST1R PTHR24416:SF113 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE-STIMULATING PROTEIN RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;phagocytosis#GO:0006909;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=32470|UniProtKB=Q6ZMV8 Q6ZMV8 ZNF730 PTHR24384:SF110 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 85-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=10305|UniProtKB=P50914 P50914 RPL14 PTHR11127:SF4 60S RIBOSOMAL PROTEIN L14 60S RIBOSOMAL PROTEIN L14 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=29995|UniProtKB=P08218 P08218 CELA2B PTHR24257:SF19 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 2B serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=25056|UniProtKB=Q9Y2M5 Q9Y2M5 KLHL20 PTHR24412:SF451 KELCH PROTEIN KELCH-LIKE PROTEIN 20 scaffold/adaptor protein#PC00226 Apoptosis signaling pathway#P00006>Smac/Diablo#P00309 HUMAN|HGNC=26809|UniProtKB=Q6XPR3 Q6XPR3 RPTN PTHR14054:SF14 REPETIN REPETIN HUMAN|HGNC=33996|UniProtKB=P0DN37 P0DN37 PPIAL4G PTHR11071:SF466 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A-LIKE 4C-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=21667|UniProtKB=Q96SN7 Q96SN7 ORAI2 PTHR31501:SF5 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 PROTEIN ORAI-2 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812;calcium ion transport#GO:0006816 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133 HUMAN|HGNC=6723|UniProtKB=Q9NQ29 Q9NQ29 LUC7L PTHR12375:SF31 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN LUC7-LIKE 1-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=8042|UniProtKB=Q9Y5Y2 Q9Y5Y2 NUBP2 PTHR23264:SF19 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2 metal cluster binding#GO:0051540;iron-sulfur cluster binding#GO:0051536;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2364|UniProtKB=O75462 O75462 CRLF1 PTHR23036:SF16 CYTOKINE RECEPTOR CYTOKINE RECEPTOR-LIKE FACTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;cytokine binding#GO:0019955 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of receptor signaling pathway via STAT#GO:1904894;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;tyrosine phosphorylation of STAT protein#GO:0007260;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;peptidyl-tyrosine modification#GO:0018212;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=126|UniProtKB=P10323 P10323 ACR PTHR24252:SF5 ACROSIN-RELATED ACROSIN serine protease#PC00203 HUMAN|HGNC=29524|UniProtKB=Q8N4E4 Q8N4E4 PDCL2 PTHR45809:SF1 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 2 viral or transposable element protein#PC00237 HUMAN|HGNC=14045|UniProtKB=Q9BYN8 Q9BYN8 MRPS26 PTHR21035:SF2 28S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 HUMAN|HGNC=14599|UniProtKB=Q9UJW2 Q9UJW2 TINAG PTHR12411:SF274 CYSTEINE PROTEASE FAMILY C1-RELATED TUBULOINTERSTITIAL NEPHRITIS ANTIGEN cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=32669|UniProtKB=Q2Q1W2 Q2Q1W2 TRIM71 PTHR24104:SF37 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM71 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=15110|UniProtKB=Q8NGR8 Q8NGR8 OR1L8 PTHR48001:SF83 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1L8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=32331|UniProtKB=Q5T5A4 Q5T5A4 C1orf194 PTHR10924:SF2 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED FELINE LEUKEMIA VIRUS SUBGROUP C RECEPTOR-RELATED PROTEIN 1-RELATED tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;metal ion transport#GO:0030001;immune system development#GO:0002520;animal organ development#GO:0048513;ion transport#GO:0006811;transport#GO:0006810;developmental process#GO:0032502;multicellular organism development#GO:0007275;hematopoietic or lymphoid organ development#GO:0048534;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;cation transport#GO:0006812;cellular process#GO:0009987;erythrocyte differentiation#GO:0030218;localization#GO:0051179;mitochondrial transport#GO:0006839;immune system process#GO:0002376;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anatomical structure development#GO:0048856;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258 HUMAN|HGNC=27338|UniProtKB=Q8N807 Q8N807 PDILT PTHR18929:SF58 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE-LIKE PROTEIN OF THE TESTIS isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;cellular process#GO:0009987;cellular response to stress#GO:0033554;protein folding#GO:0006457 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=18587|UniProtKB=O94901 O94901 SUN1 PTHR12911:SF23 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;nuclear envelope organization#GO:0006998;cellular process#GO:0009987 envelope#GO:0031975;membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=7683|UniProtKB=O15239 O15239 NDUFA1 PTHR17098:SF2 NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=30717|UniProtKB=Q7RTY3 Q7RTY3 PRSS45P PTHR24256:SF140 TRYPTASE-RELATED SERINE PROTEASE 45-RELATED serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=4286|UniProtKB=Q9NTQ9 Q9NTQ9 GJB4 PTHR11984:SF30 CONNEXIN GAP JUNCTION BETA-4 PROTEIN gap junction#PC00105 HUMAN|HGNC=1959|UniProtKB=P30532 P30532 CHRNA5 PTHR18945:SF76 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-5 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;acetylcholine receptor activity#GO:0015464;molecular transducer activity#GO:0060089;acetylcholine binding#GO:0042166;ion binding#GO:0043167;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA5#P06593;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=6309|UniProtKB=O60938 O60938 KERA PTHR45712:SF13 AGAP008170-PA KERATOCAN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=1494|UniProtKB=Q15699 Q15699 ALX1 PTHR24329:SF359 HOMEOBOX PROTEIN ARISTALESS ALX HOMEOBOX PROTEIN 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;embryonic organ morphogenesis#GO:0048562;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=18057|UniProtKB=Q63ZE4 Q63ZE4 SLC22A10 PTHR24064:SF278 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 10 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258 HUMAN|HGNC=6135|UniProtKB=O75578 O75578 ITGA10 PTHR23220:SF26 INTEGRIN ALPHA INTEGRIN ALPHA-10 integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=2257|UniProtKB=O00230 O00230 CORT PTHR22980:SF2 CORTISTATIN CORTISTATIN neuropeptide hormone activity#GO:0005184;chromatin binding#GO:0003682;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;molecular function regulator#GO:0098772;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;meiotic chromosome separation#GO:0051307;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;cellular nitrogen compound biosynthetic process#GO:0044271;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;replication fork processing#GO:0031297;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;cellular macromolecule biosynthetic process#GO:0034645;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;DNA biosynthetic process#GO:0071897;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;aromatic compound biosynthetic process#GO:0019438;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;Fanconi anaemia nuclear complex#GO:0043240;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 neuropeptide#PC00162 HUMAN|HGNC=21150|UniProtKB=Q96EQ8 Q96EQ8 RNF125 PTHR46016:SF2 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF125 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=25130|UniProtKB=Q96HH4 Q96HH4 TMEM169 PTHR31777:SF0 TRANSMEMBRANE PROTEIN 169 TRANSMEMBRANE PROTEIN 169 HUMAN|HGNC=25794|UniProtKB=Q9H8W3 Q9H8W3 FAM204A PTHR14386:SF2 PROTEIN FAM204A PROTEIN FAM204A HUMAN|HGNC=28625|UniProtKB=Q330K2 Q330K2 NDUFAF6 PTHR21181:SF13 FAMILY NOT NAMED NADH DEHYDROGENASE (UBIQUINONE) COMPLEX I, ASSEMBLY FACTOR 6 HUMAN|HGNC=7954|UniProtKB=O95502 O95502 NPTXR PTHR19277:SF94 PENTRAXIN CHROMOBOX PROTEIN HOMOLOG 6-RELATED HUMAN|HGNC=24071|UniProtKB=P0DPH8 P0DPH8 TUBA3D PTHR11588:SF113 TUBULIN TUBULIN ALPHA-3D CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 HUMAN|HGNC=90|UniProtKB=P16219 P16219 ACADS PTHR43884:SF36 ACYL-COA DEHYDROGENASE SHORT-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular lipid catabolic process#GO:0044242;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 dehydrogenase#PC00092 HUMAN|HGNC=17836|UniProtKB=Q5I0G3 Q5I0G3 MDH1B PTHR23382:SF1 MALATE DEHYDROGENASE MALATE DEHYDROGENASE 1B-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092 HUMAN|HGNC=28538|UniProtKB=Q8NCF0 Q8NCF0 CLEC18C PTHR10334:SF521 CYSTEINE-RICH SECRETORY PROTEIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 18 MEMBER A-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=30626|UniProtKB=Q96MU7 Q96MU7 YTHDC1 PTHR12357:SF3 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=32071|UniProtKB=Q5SZI1 Q5SZI1 LDLRAD2 PTHR24652:SF67 LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2 LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=28767|UniProtKB=Q587I9 Q587I9 SFT2D3 PTHR23137:SF36 UNCHARACTERIZED VESICLE TRANSPORT PROTEIN SFT2C HUMAN|HGNC=37244|UniProtKB=O75264 O75264 SMIM24 PTHR15296:SF2 MEMBRANE-ASSOCIATED PROTEIN MAP17 SMALL INTEGRAL MEMBRANE PROTEIN 24 HUMAN|HGNC=25742|UniProtKB=Q8IWC1 Q8IWC1 MAP7D3 PTHR15073:SF5 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 3 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=12425|UniProtKB=O75386 O75386 TULP3 PTHR16517:SF138 TUBBY-RELATED TUBBY-RELATED PROTEIN 3 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;cellular protein localization#GO:0034613;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=32063|UniProtKB=P0DPA2 P0DPA2 VSIG8 PTHR45166:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 8 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 8 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=7030|UniProtKB=Q9UBP6 Q9UBP6 METTL1 PTHR23417:SF24 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 RNA processing factor#PC00147 HUMAN|HGNC=17493|UniProtKB=O75496 O75496 GMNN PTHR13372:SF4 GEMININ GEMININ cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of DNA replication#GO:0008156;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA biosynthetic process#GO:0071897;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;regulation of cell cycle#GO:0051726;DNA replication#GO:0006260;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of DNA replication#GO:0006275;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=14462|UniProtKB=Q9UGV2 Q9UGV2 NDRG3 PTHR11034:SF20 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 serine protease#PC00203 HUMAN|HGNC=11332|UniProtKB=P32745 P32745 SSTR3 PTHR24229:SF42 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 3 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=26879|UniProtKB=Q8N7P1 Q8N7P1 PLD5 PTHR10185:SF9 PHOSPHOLIPASE D - RELATED INACTIVE PHOSPHOLIPASE D5 phospholipase#PC00186 HUMAN|HGNC=17326|UniProtKB=P02814 P02814 SMR3B PTHR14179:SF13 SMR1-RELATED SUBMAXILLARY GLAND ANDROGEN-REGULATED PROTEIN 3B protease inhibitor#PC00191 HUMAN|HGNC=26084|UniProtKB=Q7Z2X4 Q7Z2X4 PID1 PTHR16265:SF1 PTB-CONTAINING, CUBILIN AND LRP1-INTERACTING PROTEIN PTB-CONTAINING, CUBILIN AND LRP1-INTERACTING PROTEIN regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;regulation of reactive oxygen species metabolic process#GO:2000377;transmembrane transport#GO:0055085;transport#GO:0006810;regulation of localization#GO:0032879;cellular metabolic process#GO:0044237;negative regulation of transport#GO:0051051;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643;localization#GO:0051179;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=26864|UniProtKB=Q8IY85 Q8IY85 EFCAB13 PTHR22656:SF1 UNCHARACTERIZED EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 13 HUMAN|HGNC=24508|UniProtKB=B4DYI2 B4DYI2 SPATA31C2 PTHR21859:SF44 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31C1-RELATED HUMAN|HGNC=3342|UniProtKB=Q05925 Q05925 EN1 PTHR24341:SF4 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN ENGRAILED-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 HUMAN|HGNC=26729|UniProtKB=A6NNA2 A6NNA2 SRRM3 PTHR34755:SF2 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 HUMAN|HGNC=15905|UniProtKB=Q9Y468 Q9Y468 L3MBTL1 PTHR12247:SF69 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 1 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=20597|UniProtKB=P61960 P61960 UFM1 PTHR15825:SF5 UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-FOLD MODIFIER 1 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=31955|UniProtKB=P0CB38 P0CB38 PABPC4L PTHR24012:SF776 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 4-LIKE nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=4738|UniProtKB=Q16777 Q16777 H2AC20 PTHR23430:SF130 HISTONE H2A HISTONE H2A TYPE 2-C heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=25826|UniProtKB=Q9H0V1 Q9H0V1 TMEM168 PTHR14437:SF2 TRANSMEMBRANE PROTEIN 168 TRANSMEMBRANE PROTEIN 168 HUMAN|HGNC=10478|UniProtKB=P28702 P28702 RXRB PTHR24083:SF90 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;response to lipid#GO:0033993;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=18734|UniProtKB=P42285 P42285 MTREX PTHR12131:SF7 ATP-DEPENDENT RNA AND DNA HELICASE EXOSOME RNA HELICASE MTR4 catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;organic substance catabolic process#GO:1901575;maturation of 5.8S rRNA#GO:0000460;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 HUMAN|HGNC=13211|UniProtKB=P98194 P98194 ATP2C1 PTHR42861:SF2 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 1 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=11996|UniProtKB=Q5JU69 Q5JU69 TOR2A PTHR10760:SF4 TORSIN TORSIN-2A pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 HUMAN|HGNC=4425|UniProtKB=Q08379 Q08379 GOLGA2 PTHR10881:SF58 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 2 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=42975|UniProtKB=Q96EF9 Q96EF9 ZHX1-C8orf76 PTHR31919:SF1 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 homeodomain transcription factor#PC00119 HUMAN|HGNC=6390|UniProtKB=Q9UIL4 Q9UIL4 KIF25 PTHR24115:SF421 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF25 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=20388|UniProtKB=Q9BQ08 Q9BQ08 RETNLB PTHR21101:SF13 RESISTIN RESISTIN-LIKE BETA extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=24103|UniProtKB=Q9H1I8 Q9H1I8 ASCC2 PTHR21494:SF0 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 HUMAN|HGNC=30938|UniProtKB=Q86Y13 Q86Y13 DZIP3 PTHR15727:SF4 RING FINGER PROTEIN 214 E3 UBIQUITIN-PROTEIN LIGASE DZIP3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;catalytic activity, acting on a protein#GO:0140096;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=21755|UniProtKB=Q8NET6 Q8NET6 CHST13 PTHR12137:SF60 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 13 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=6110|UniProtKB=P46940 P46940 IQGAP1 PTHR14149:SF15 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP1 GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;GTPase binding#GO:0051020;enzyme binding#GO:0019899;calmodulin binding#GO:0005516;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rho GTPase binding#GO:0017048;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;Rac GTPase binding#GO:0048365;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 GTPase-activating protein#PC00257 HUMAN|HGNC=15146|UniProtKB=Q8NGH3 Q8NGH3 OR2D3 PTHR26453:SF136 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D3 transmembrane signal receptor#PC00197 HUMAN|HGNC=16961|UniProtKB=Q15762 Q15762 CD226 PTHR47011:SF1 CD226 ANTIGEN CD226 ANTIGEN positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;positive regulation of signal transduction#GO:0009967;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;gene expression#GO:0010467;regulation of cytokine production involved in immune response#GO:0002718;lymphocyte mediated immunity#GO:0002449;positive regulation of leukocyte activation#GO:0002696;production of molecular mediator of immune response#GO:0002440;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;regulation of signal transduction#GO:0009966;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;positive regulation of immune effector process#GO:0002699;positive regulation of cytokine production#GO:0001819;regulation of adaptive immune response#GO:0002819;positive regulation of signaling#GO:0023056;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of defense response#GO:0031347;regulation of production of molecular mediator of immune response#GO:0002700;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of defense response#GO:0031349;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;regulation of signaling#GO:0023051;positive regulation of adaptive immune response#GO:0002821;cytokine production#GO:0001816;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immunoglobulin mediated immune response#GO:0002891;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;regulation of immune effector process#GO:0002697;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of response to biotic stimulus#GO:0002833;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=20914|UniProtKB=Q6QNY0 Q6QNY0 BLOC1S3 PTHR31974:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 3 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 3 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622;BLOC-1 complex#GO:0031083 HUMAN|HGNC=25115|UniProtKB=Q9BUA3 Q9BUA3 SPINDOC PTHR34589:SF1 SIMILAR TO RIKEN CDNA 2700081O15 SPINDLIN INTERACTOR AND REPRESSOR OF CHROMATIN-BINDING PROTEIN negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=4421|UniProtKB=P30968 P30968 GNRHR PTHR24241:SF22 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GONADOTROPIN-RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>GnRHR#P06727;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Gonadotropin-releasing hormone receptor pathway#P06664>GnRHR#G06892;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Gonadotropin-releasing hormone receptor pathway#P06664>GnRHR#G06676 HUMAN|HGNC=26195|UniProtKB=Q86XH1 Q86XH1 IQCA1 PTHR14690:SF8 UNCHARACTERIZED DYNEIN REGULATORY COMPLEX PROTEIN 11 HUMAN|HGNC=7428|UniProtKB=Q14872 Q14872 MTF1 PTHR19818:SF131 ZINC FINGER PROTEIN ZIC AND GLI METAL REGULATORY TRANSCRIPTION FACTOR 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7612|UniProtKB=P15173 P15173 MYOG PTHR11534:SF5 MYOGENIC FACTOR MYOGENIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;muscle structure development#GO:0061061;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of cell differentiation#GO:0045597;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=1230|UniProtKB=Q9UBG3 Q9UBG3 CRNN PTHR11639:SF26 S100 CALCIUM-BINDING PROTEIN CORNULIN response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;positive regulation of cell cycle#GO:0045787;regulation of RNA biosynthetic process#GO:2001141;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;inositol lipid-mediated signaling#GO:0048017;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cell cycle G1/S phase transition#GO:0044843;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;positive regulation of cell cycle process#GO:0090068;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;phosphatidylinositol-mediated signaling#GO:0048015;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;phosphatidylinositol 3-kinase signaling#GO:0014065;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of phosphatidylinositol 3-kinase signaling#GO:0014066;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 calmodulin-related#PC00061 HUMAN|HGNC=30498|UniProtKB=Q8TA94 Q8TA94 ZNF563 PTHR24379:SF14 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 563 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4016|UniProtKB=Q11128 Q11128 FUT5 PTHR11929:SF11 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE FUT5 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111 HUMAN|HGNC=15389|UniProtKB=Q8NGA6 Q8NGA6 OR10H5 PTHR24247:SF122 5-HYDROXYTRYPTAMINE RECEPTOR OLFACTORY RECEPTOR 10H1-RELATED cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=26847|UniProtKB=Q8N815 Q8N815 CNTD1 PTHR21615:SF2 UNCHARACTERIZED CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;M phase#GO:0000279;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;meiosis I cell cycle phase#GO:0098764;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;cell cycle#GO:0007049;organelle fission#GO:0048285;biological phase#GO:0044848;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;site of double-strand break#GO:0035861;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6250|UniProtKB=O95259 O95259 KCNH1 PTHR10217:SF530 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=15222|UniProtKB=Q8NGK4 Q8NGK4 OR52K1 PTHR26450:SF401 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52K1 transmembrane signal receptor#PC00197 HUMAN|HGNC=21268|UniProtKB=Q8IZ07 Q8IZ07 ANKRD13A PTHR12447:SF4 UNCHARACTERIZED WITH ANKYRIN REPEAT DOMAIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=23230|UniProtKB=Q9GZZ9 Q9GZZ9 UBA5 PTHR10953:SF9 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 5 ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=4504|UniProtKB=O75473 O75473 LGR5 PTHR24372:SF71 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=30525|UniProtKB=Q96A59 Q96A59 MARVELD3 PTHR21737:SF1 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 MARVEL DOMAIN-CONTAINING PROTEIN 3 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of localization#GO:0032879;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;regulation of cell migration#GO:0030334;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;negative regulation of cellular component movement#GO:0051271;cell junction assembly#GO:0034329;regulation of gene expression#GO:0010468;negative regulation of cell motility#GO:2000146;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cellular component movement#GO:0051270;heterocycle metabolic process#GO:0046483;cell-cell junction organization#GO:0045216;cellular component assembly#GO:0022607;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;cell-cell junction assembly#GO:0007043;regulation of cell motility#GO:2000145;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cell junction organization#GO:0034330;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;mRNA processing#GO:0006397;multicellular organismal process#GO:0032501;RNA splicing, via transesterification reactions#GO:0000375;cell migration#GO:0016477;locomotion#GO:0040011;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;apical junction complex#GO:0043296 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20596|UniProtKB=Q8NEM7 Q8NEM7 SUPT20H PTHR13526:SF18 TRANSCRIPTION FACTOR SPT20 HOMOLOG TRANSCRIPTION FACTOR SPT20 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=20259|UniProtKB=Q9Y2K1 Q9Y2K1 ZBTB1 PTHR24399:SF21 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3468|UniProtKB=Q92731 Q92731 ESR2 PTHR48092:SF12 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN RECEPTOR BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=2347|UniProtKB=O43889 O43889 CREB3 PTHR45996:SF4 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 HUMAN|HGNC=24010|UniProtKB=Q7Z4T9 Q7Z4T9 CFAP91 PTHR22455:SF10 UNCHARACTERIZED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91 HUMAN|HGNC=11164|UniProtKB=P63162 P63162 SNRPN PTHR10701:SF3 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN N cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Lsm2-8 complex#GO:0120115;U2-type prespliceosome#GO:0071004;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974 RNA splicing factor#PC00148 Gonadotropin-releasing hormone receptor pathway#P06664>SNURF#P06808 HUMAN|HGNC=29945|UniProtKB=Q6N022 Q6N022 TENM4 PTHR11219:SF9 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-4 identical protein binding#GO:0042802;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein homodimerization activity#GO:0042803;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=30804|UniProtKB=Q8IZ13 Q8IZ13 ZBED8 PTHR45935:SF18 PROTEIN ZBED8-RELATED PROTEIN ZBED8 HUMAN|HGNC=11075|UniProtKB=O14745 O14745 SLC9A3R1 PTHR14191:SF7 PDZ DOMAIN CONTAINING PROTEIN NA(+)/H(+) EXCHANGE REGULATORY COFACTOR NHE-RF1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 HUMAN|HGNC=17379|UniProtKB=Q7Z5R6 Q7Z5R6 APBB1IP PTHR11243:SF14 GROWTH FACTOR RECEPTOR-BOUND PROTEIN AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN cytoplasm#GO:0005737;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=8856|UniProtKB=O75381 O75381 PEX14 PTHR23058:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX14 PEROXISOMAL MEMBRANE PROTEIN PEX14 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein targeting to peroxisome#GO:0006625;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein localization to peroxisome#GO:0072662;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;microbody membrane#GO:0031903;protein-containing complex#GO:0032991;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777 primary active transporter#PC00068 HUMAN|HGNC=26539|UniProtKB=Q5T197 Q5T197 DCST1 PTHR21041:SF18 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE DCST1 HUMAN|HGNC=25026|UniProtKB=Q8NEB5 Q8NEB5 PLPP5 PTHR10165:SF87 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 5 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphatase#PC00181 HUMAN|HGNC=15101|UniProtKB=Q8NH95 Q8NH95 OR13C6P PTHR26453:SF635 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C7-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=4917|UniProtKB=Q9BW71 Q9BW71 HIRIP3 PTHR15410:SF2 HIRA-INTERACTING PROTEIN 3 HIRA-INTERACTING PROTEIN 3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=17082|UniProtKB=Q15049 Q15049 MLC1 PTHR17597:SF0 MEMBRANE PROTEIN MLC1 MEMBRANE PROTEIN MLC1 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to osmotic stress#GO:0006970;regulation of response to stress#GO:0080134;biological regulation#GO:0065007;response to abiotic stimulus#GO:0009628 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=10472|UniProtKB=Q13950 Q13950 RUNX2 PTHR11950:SF7 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;hematopoietic or lymphoid organ development#GO:0048534;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Runt transcription factor#PC00254 HUMAN|HGNC=6769|UniProtKB=P84022 P84022 SMAD3 PTHR13703:SF53 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 3 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;ubiquitin protein ligase binding#GO:0031625;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;nucleobase-containing compound metabolic process#GO:0006139;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;response to BMP#GO:0071772;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;BMP signaling pathway#GO:0030509;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;response to growth factor#GO:0070848;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to growth factor stimulus#GO:0071363;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 HUMAN|HGNC=4180|UniProtKB=Q04446 Q04446 GBE1 PTHR43651:SF3 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 amylase#PC00048 HUMAN|Ensembl=ENSG00000283716|UniProtKB=A0A5F9Z9Y6 A0A5F9Z9Y6 ENSG00000283716 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=2458|UniProtKB=Q8NEV1 Q8NEV1 CSNK2A3 PTHR24054:SF16 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;peptidyl-threonine phosphorylation#GO:0018107;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;cell cycle#GO:0007049;peptidyl-serine modification#GO:0018209;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 HUMAN|HGNC=3007|UniProtKB=Q9P2X0 Q9P2X0 DPM3 PTHR16433:SF0 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein lipidation#GO:0006497;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;mannosyltransferase complex#GO:0031501 transferase#PC00220 HUMAN|HGNC=18983|UniProtKB=Q8IUM7 Q8IUM7 NPAS4 PTHR23043:SF24 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=6363|UniProtKB=P20151 P20151 KLK2 PTHR24271:SF75 KALLIKREIN-RELATED KALLIKREIN-2 blood circulation#GO:0008015;macromolecule metabolic process#GO:0043170;system process#GO:0003008;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;regulation of systemic arterial blood pressure#GO:0003073;circulatory system process#GO:0003013;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;regulation of blood pressure#GO:0008217;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=143|UniProtKB=P68032 P68032 ACTC1 PTHR11937:SF176 ACTIN ACTIN, ALPHA CARDIAC MUSCLE 1 actin and actin related protein#PC00039 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 HUMAN|HGNC=10527|UniProtKB=Q9BXA9 Q9BXA9 SALL3 PTHR23233:SF46 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20956|UniProtKB=O75167 O75167 PHACTR2 PTHR12751:SF5 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 phosphatase modulator#PC00184 HUMAN|HGNC=4097|UniProtKB=O95257 O95257 GADD45G PTHR10411:SF4 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 p53 pathway#P00059>GADD45#G01575;p53 pathway#P00059>GADD45#P04626 HUMAN|HGNC=16763|UniProtKB=Q9Y2Y4 Q9Y2Y4 ZBTB32 PTHR24399:SF40 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 32 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25129|UniProtKB=Q8IW92 Q8IW92 GLB1L2 PTHR23421:SF53 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE-1-LIKE PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 galactosidase#PC00104 HUMAN|HGNC=25925|UniProtKB=Q96K30 Q96K30 RITA1 PTHR34917:SF1 RBPJ-INTERACTING AND TUBULIN-ASSOCIATED PROTEIN 1 RBPJ-INTERACTING AND TUBULIN-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;nuclear transport#GO:0051169;negative regulation of cell communication#GO:0010648;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of Notch signaling pathway#GO:0045746;regulation of response to stimulus#GO:0048583;localization#GO:0051179;response to stimulus#GO:0050896;nuclear export#GO:0051168;regulation of cellular process#GO:0050794;nucleocytoplasmic transport#GO:0006913;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;negative regulation of signal transduction#GO:0009968;intracellular transport#GO:0046907;Notch signaling pathway#GO:0007219 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=13839|UniProtKB=Q8IWK6 Q8IWK6 ADGRA3 PTHR45930:SF2 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=32324|UniProtKB=Q6ZSA7 Q6ZSA7 LRRC55 PTHR46473:SF5 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 55 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;molecular function regulator#GO:0098772;protein binding#GO:0005515;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 HUMAN|HGNC=11955|UniProtKB=Q8TF68 Q8TF68 ZNF384 PTHR24376:SF130 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 384 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=31291|UniProtKB=A6NMS3 A6NMS3 OR5K4 PTHR26452:SF795 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5K4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=20299|UniProtKB=Q9BWV3 Q9BWV3 CDADC1 PTHR11086:SF14 DEOXYCYTIDYLATE DEAMINASE-RELATED CYTIDINE AND DCMP DEAMINASE DOMAIN-CONTAINING PROTEIN 1 deaminase#PC00088 HUMAN|HGNC=27010|UniProtKB=Q17R31 Q17R31 TATDN3 PTHR46317:SF1 HYDROLASE OF PHP SUPERFAMILY-RELATED PROTEIN DEOXYRIBONUCLEASE TATDN3-RELATED hydrolase#PC00121 HUMAN|HGNC=18068|UniProtKB=Q8IY34 Q8IY34 SLC15A3 PTHR11654:SF95 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 3 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 HUMAN|HGNC=180|UniProtKB=P14621 P14621 ACYP2 PTHR10029:SF20 ACYLPHOSPHATASE ACYLPHOSPHATASE-2 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 phosphatase#PC00181 HUMAN|HGNC=26765|UniProtKB=Q68DI1 Q68DI1 ZNF776 PTHR24377:SF725 IP01015P-RELATED ZINC FINGER PROTEIN 776 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=264|UniProtKB=P29275 P29275 ADORA2B PTHR24246:SF18 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A2B G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 HUMAN|HGNC=10571|UniProtKB=O00767 O00767 SCD PTHR11351:SF73 ACYL-COA DESATURASE ACYL-COA DESATURASE cation binding#GO:0043169;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 response to organic substance#GO:0010033;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;response to oxygen-containing compound#GO:1901700;monocarboxylic acid biosynthetic process#GO:0072330;response to lipid#GO:0033993;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;response to chemical#GO:0042221;unsaturated fatty acid biosynthetic process#GO:0006636;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=1472|UniProtKB=P49913 P49913 CAMP PTHR10206:SF2 CATHELICIDIN CATHELICIDIN ANTIMICROBIAL PEPTIDE carbohydrate derivative binding#GO:0097367;lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to Gram-positive bacterium#GO:0050830;defense response to Gram-negative bacterium#GO:0050829;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;antimicrobial humoral response#GO:0019730;defense response to other organism#GO:0098542;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=19826|UniProtKB=Q86U38 Q86U38 NOP9 PTHR13102:SF0 NUCLEOLAR PROTEIN 9 NUCLEOLAR PROTEIN 9 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;rRNA processing#GO:0006364;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;ncRNA metabolic process#GO:0034660;ncRNA processing#GO:0034470;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;ribosome biogenesis#GO:0042254;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;rRNA metabolic process#GO:0016072;protein transport#GO:0015031;intracellular transport#GO:0046907;maturation of SSU-rRNA#GO:0030490;protein-containing complex localization#GO:0031503;cellular aromatic compound metabolic process#GO:0006725;ribosomal subunit export from nucleus#GO:0000054;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;RNA processing#GO:0006396;ribonucleoprotein complex export from nucleus#GO:0071426;amide transport#GO:0042886;organic substance transport#GO:0071702;organic cyclic compound metabolic process#GO:1901360;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;protein export from nucleus#GO:0006611;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;cleavage involved in rRNA processing#GO:0000469;heterocycle metabolic process#GO:0046483;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex localization#GO:0071166;cellular process#GO:0009987;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;endonucleolytic cleavage involved in rRNA processing#GO:0000478;RNA export from nucleus#GO:0006405;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 HUMAN|HGNC=21674|UniProtKB=Q8NA03 Q8NA03 FSIP1 PTHR22012:SF2 FIBROUS SHEATH INTERACTING PROTEIN 1 FIBROUS SHEATH-INTERACTING PROTEIN 1 HUMAN|HGNC=25770|UniProtKB=Q9H977 Q9H977 WDR54 PTHR13720:SF40 WD-40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 54 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 HUMAN|HGNC=17962|UniProtKB=Q96LB2 Q96LB2 MRGPRX1 PTHR11334:SF22 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MRG-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=24213|UniProtKB=Q8IUL8 Q8IUL8 CILP2 PTHR15031:SF0 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 2 HUMAN|HGNC=4812|UniProtKB=P54257 P54257 HAP1 PTHR15751:SF14 TRAFFICKING KINESIN-BINDING PROTEIN HUNTINGTIN-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;signaling receptor binding#GO:0005102;binding#GO:0005488 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;nervous system development#GO:0007399;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;establishment of organelle localization#GO:0051656;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;protein targeting#GO:0006605;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;transport along microtubule#GO:0010970;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;mitochondrion distribution#GO:0048311;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;neurogenesis#GO:0022008;signal transduction#GO:0007165;macromolecule localization#GO:0033036;response to growth factor#GO:0070848;cellular protein localization#GO:0034613;developmental process#GO:0032502;transport#GO:0006810;amide transport#GO:0042886;axo-dendritic transport#GO:0008088;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;cytoskeleton-dependent intracellular transport#GO:0030705;mitochondrion organization#GO:0007005;signaling#GO:0023052;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;microtubule-based transport#GO:0099111;response to chemical#GO:0042221;microtubule-based process#GO:0007017;cellular response to growth factor stimulus#GO:0071363;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;dendrite#GO:0030425;cell periphery#GO:0071944;mitochondrion#GO:0005739;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Huntington disease#P00029>HAP1#P00762 HUMAN|HGNC=24808|UniProtKB=O14545 O14545 TRAFD1 PTHR16295:SF19 TRAF-TYPE ZINC FINGER PROTEIN-RELATED TRAF-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11324|UniProtKB=P43308 P43308 SSR2 PTHR12861:SF3 TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=30526|UniProtKB=Q86TL2 Q86TL2 STIMATE PTHR31735:SF2 VACUOLAR MEMBRANE PROTEIN YPL162C STORE-OPERATED CALCIUM ENTRY REGULATOR STIMATE calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;channel activity#GO:0015267;transporter activity#GO:0005215 positive regulation of ion transport#GO:0043270;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of molecular function#GO:0044093;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;positive regulation of transmembrane transport#GO:0034764;divalent inorganic cation transport#GO:0072511;regulation of transmembrane transporter activity#GO:0022898;intracellular signal transduction#GO:0035556;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;regulation of calcium ion transport#GO:0051924;positive regulation of ion transmembrane transporter activity#GO:0032414;positive regulation of transport#GO:0051050;cell communication#GO:0007154;positive regulation of calcium ion transport#GO:0051928;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;regulation of ion transmembrane transport#GO:0034765;positive regulation of transporter activity#GO:0032411;regulation of cellular process#GO:0050794;positive regulation of ion transmembrane transport#GO:0034767;biological regulation#GO:0065007;regulation of ion transport#GO:0043269 endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;cortical endoplasmic reticulum#GO:0032541;plasma membrane#GO:0005886 HUMAN|HGNC=9230|UniProtKB=O43688 O43688 PLPP2 PTHR10165:SF25 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=25430|UniProtKB=Q8IYG6 Q8IYG6 LRRC56 PTHR22708:SF0 UNCHARACTERIZED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56 HUMAN|HGNC=1240|UniProtKB=Q9UBS9 Q9UBS9 SUCO PTHR12953:SF0 MEMBRANE PROTEIN CH1 RELATED SUN DOMAIN-CONTAINING OSSIFICATION FACTOR cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 structural protein#PC00211 HUMAN|HGNC=21014|UniProtKB=Q9H6X2 Q9H6X2 ANTXR1 PTHR16059:SF11 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR 1 cell adhesion molecule#PC00069 HUMAN|HGNC=3076|UniProtKB=Q99956 Q99956 DUSP9 PTHR10159:SF388 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 9 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;kinase activity#GO:0016301;phosphoprotein phosphatase activity#GO:0004721;kinase binding#GO:0019900;protein kinase activity#GO:0004672;phosphoric ester hydrolase activity#GO:0042578;MAP kinase activity#GO:0004707;transferase activity#GO:0016740;hydrolase activity#GO:0016787;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of MAP kinase activity#GO:0043407;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=40033|UniProtKB=Q9H693 Q9H693 C16orf95 PTHR14693:SF0 RIKEN CDNA 1700018B08 RIKEN CDNA 1700018B08 GENE HUMAN|HGNC=26242|UniProtKB=Q6ZT98 Q6ZT98 TTLL7 PTHR12241:SF147 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL7 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=10251|UniProtKB=Q13464 Q13464 ROCK1 PTHR22988:SF33 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;GTPase binding#GO:0051020;enzyme binding#GO:0019899;GTP-Rho binding#GO:0017049;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;kinase activity#GO:0016301;protein kinase activity#GO:0004672;Ras GTPase binding#GO:0017016;transferase activity#GO:0016740;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;nuclear division#GO:0000280;Ras protein signal transduction#GO:0007265;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cell communication#GO:0007154;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;embryo development#GO:0009790;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cell division#GO:0051301;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;cell cycle process#GO:0022402;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;mitotic cytokinesis#GO:0000281;cell junction assembly#GO:0034329;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;cytokinesis#GO:0000910;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;membrane fission#GO:0090148;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;response to stimulus#GO:0050896;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;cell junction organization#GO:0034330;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell junction assembly#GO:1901888;actin cytoskeleton organization#GO:0030036;embryonic morphogenesis#GO:0048598;cortical actin cytoskeleton organization#GO:0030866 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>ROCK#P00881;CCKR signaling map#P06959>ROCK1#P07033;Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519 HUMAN|HGNC=29567|UniProtKB=Q96GR2 Q96GR2 ACSBG1 PTHR24096:SF296 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ACSBG1 ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 long-chain fatty acid metabolic process#GO:0001676;organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 HUMAN|HGNC=5800|UniProtKB=A0A075B6S2 A0A075B6S2 IGKV2D-29 PTHR23267:SF380 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-29 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=3148|UniProtKB=P19971 P19971 TYMP PTHR10515:SF0 THYMIDINE PHOSPHORYLASE THYMIDINE PHOSPHORYLASE cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 glycosyltransferase#PC00111 Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine phosphorylase#P03148;Salvage pyrimidine deoxyribonucleotides#P02774>Uracil phosphorylase#P03145;Pyrimidine Metabolism#P02771>Nucleoside Phosphorylase#P03126 HUMAN|HGNC=19100|UniProtKB=Q5VWK5 Q5VWK5 IL23R PTHR23036:SF112 CYTOKINE RECEPTOR INTERLEUKIN-23 RECEPTOR signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;growth factor receptor binding#GO:0070851;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;cytokine receptor binding#GO:0005126 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 membrane protein complex#GO:0098796;leaflet of membrane bilayer#GO:0097478;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=12363|UniProtKB=P49815 P49815 TSC2 PTHR10063:SF0 TUBERIN TUBERIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 p53 pathway by glucose deprivation#P04397>TSC2#P04644;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC2#P04494;p53 pathway by glucose deprivation#P04397>TSC2#G04706 HUMAN|HGNC=11101|UniProtKB=O60264 O60264 SMARCA5 PTHR10799:SF997 SNF2/RAD54 HELICASE FAMILY SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5 pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=6359|UniProtKB=Q9UBX7 Q9UBX7 KLK11 PTHR24271:SF68 KALLIKREIN-RELATED KALLIKREIN-11 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=26909|UniProtKB=P83105 P83105 HTRA4 PTHR22939:SF105 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA4 serine protease#PC00203 HUMAN|HGNC=12869|UniProtKB=P17010 P17010 ZFX PTHR24406:SF6 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER X-CHROMOSOMAL PROTEIN heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=5920|UniProtKB=A0A075B6I1 A0A075B6I1 IGLV4-60 PTHR23267:SF323 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-60 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=14406|UniProtKB=Q9H3S7 Q9H3S7 PTPN23 PTHR23030:SF30 PCD6 INTERACTING PROTEIN-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23 membrane traffic protein#PC00150 HUMAN|HGNC=11983|UniProtKB=O75674 O75674 TOM1L1 PTHR13856:SF28 VHS DOMAIN CONTAINING PROTEIN FAMILY TOM1-LIKE PROTEIN 1 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=24325|UniProtKB=Q9NXV6 Q9NXV6 CDKN2AIP PTHR16148:SF11 NF-KAPPA-B-REPRESSING FACTOR-RELATED CDKN2A-INTERACTING PROTEIN-RELATED membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=9320|UniProtKB=Q8TF05 Q8TF05 PPP4R1 PTHR10648:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT SERINE/THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1 phosphatase binding#GO:0019902;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;protein serine/threonine phosphatase activity#GO:0004722;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 HUMAN|HGNC=7839|UniProtKB=P78426 P78426 NKX6-1 PTHR24340:SF31 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-6.1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=19698|UniProtKB=Q8TDN2 Q8TDN2 KCNV2 PTHR11537:SF40 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY V MEMBER 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=12369|UniProtKB=Q96PP4 Q96PP4 TSGA13 PTHR37352:SF1 TESTIS-SPECIFIC GENE 13 PROTEIN TESTIS-SPECIFIC GENE 13 PROTEIN HUMAN|HGNC=18453|UniProtKB=Q8NCW5 Q8NCW5 NAXE PTHR13232:SF11 NAD(P)H-HYDRATE EPIMERASE NAD(P)H-HYDRATE EPIMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 epimerase/racemase#PC00096 HUMAN|HGNC=20582|UniProtKB=Q7Z449 Q7Z449 CYP2U1 PTHR24300:SF281 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2U1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=29642|UniProtKB=A6NFN9 A6NFN9 ANKUB1 PTHR46885:SF1 PROTEIN ANKUB1 PROTEIN ANKUB1 HUMAN|HGNC=17468|UniProtKB=Q96HC4 Q96HC4 PDLIM5 PTHR24214:SF32 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 5 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=15381|UniProtKB=Q8NGA8 Q8NGA8 OR4F17 PTHR48002:SF51 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4F17-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=1372|UniProtKB=Q9ULX7 Q9ULX7 CA14 PTHR18952:SF84 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 14 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=26181|UniProtKB=Q96G75 Q96G75 RMND5B PTHR12170:SF6 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE RMND5B transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=19975|UniProtKB=Q8IZV5 Q8IZV5 RDH10 PTHR24322:SF731 PKSB RETINOL DEHYDROGENASE 10 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=21225|UniProtKB=Q75N03 Q75N03 CBLL1 PTHR13480:SF2 E3 UBIQUITIN-PROTEIN LIGASE HAKAI-RELATED E3 UBIQUITIN-PROTEIN LIGASE HAKAI ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;biological adhesion#GO:0022610;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;protein metabolic process#GO:0019538;regulation of cell adhesion#GO:0030155;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=8155|UniProtKB=P41146 P41146 OPRL1 PTHR24229:SF11 NEUROPEPTIDES RECEPTOR NOCICEPTIN RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of pain#GO:0019233;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 HUMAN|HGNC=13817|UniProtKB=Q9NS84 Q9NS84 CHST7 PTHR10704:SF5 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 7 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;chondroitin sulfate metabolic process#GO:0030204;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;proteoglycan metabolic process#GO:0006029;chondroitin sulfate proteoglycan metabolic process#GO:0050654;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;glycosaminoglycan biosynthetic process#GO:0006024;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281 transferase#PC00220 HUMAN|HGNC=6970|UniProtKB=P40925 P40925 MDH1 PTHR23382:SF3 MALATE DEHYDROGENASE MALATE DEHYDROGENASE, CYTOPLASMIC catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092 TCA cycle#P00051>Malate Dehydrogenase#P01270 HUMAN|Ensembl=ENSG00000260220|UniProtKB=A0A096LP49 A0A096LP49 CCDC187 PTHR13958:SF5 CENTROSOME-ASSOCIATED PROTEIN 350 COILED-COIL DOMAIN-CONTAINING PROTEIN 187 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=10065|UniProtKB=Q9HCM9 Q9HCM9 TRIM39 PTHR24103:SF639 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM39 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=19751|UniProtKB=O75044 O75044 SRGAP2 PTHR14166:SF6 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 2-RELATED Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048 regulation of cellular component movement#GO:0051270;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;localization of cell#GO:0051674;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of cell motility#GO:2000146;cell migration#GO:0016477;locomotion#GO:0040011;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=23697|UniProtKB=Q86UU1 Q86UU1 PHLDB1 PTHR12156:SF23 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 1 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular#GO:0005622 HUMAN|HGNC=9644|UniProtKB=Q06124 Q06124 PTPN11 PTHR46559:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 protein phosphatase#PC00195 CCKR signaling map#P06959>SHP-2#P07028;FGF signaling pathway#P00021>SHP2#P00647;Angiogenesis#P00005>SHP2#P00181;Interferon-gamma signaling pathway#P00035>PTP#P00960 HUMAN|HGNC=9656|UniProtKB=P29074 P29074 PTPN4 PTHR45706:SF7 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 4 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 protein phosphatase#PC00195 HUMAN|HGNC=2053|UniProtKB=Q92478 Q92478 CLEC2B PTHR45710:SF15 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER B external side of plasma membrane#GO:0009897;leaflet of membrane bilayer#GO:0097478;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=5289|UniProtKB=P28221 P28221 HTR1D PTHR24247:SF17 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1D cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;negative regulation of biological process#GO:0048519;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;negative regulation of intracellular signal transduction#GO:1902532;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;negative regulation of catalytic activity#GO:0043086;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935;negative regulation of molecular function#GO:0044092 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 HUMAN|HGNC=11784|UniProtKB=P07204 P07204 THBD PTHR24036:SF5 SKELETOR-RELATED THROMBOMODULIN transmembrane signal receptor#PC00197 Blood coagulation#P00011>Thrombomodulin#P00457 HUMAN|HGNC=15553|UniProtKB=Q96SF2 Q96SF2 CCT8L2 PTHR11353:SF100 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT THETA-LIKE 1-RELATED protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;chaperone complex#GO:0101031;cellular anatomical entity#GO:0110165;chaperonin-containing T-complex#GO:0005832;intracellular#GO:0005622 chaperonin#PC00073 HUMAN|HGNC=15245|UniProtKB=Q8NGI3 Q8NGI3 OR56B1 PTHR26450:SF69 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 56B1 transmembrane signal receptor#PC00197 HUMAN|HGNC=14673|UniProtKB=Q9BQS8 Q9BQS8 FYCO1 PTHR46753:SF2 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;positive regulation of organelle organization#GO:0010638;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;positive regulation of cellular catabolic process#GO:0031331;microtubule-based movement#GO:0007018;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;catabolic process#GO:0009056;autophagosome maturation#GO:0097352;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;protein-containing complex disassembly#GO:0032984;vesicle localization#GO:0051648;regulation of organelle organization#GO:0033043;regulation of autophagy#GO:0010506;cellular metabolic process#GO:0044237;regulation of macroautophagy#GO:0016241;cellular component organization#GO:0016043;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;transport along microtubule#GO:0010970;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;positive regulation of catabolic process#GO:0009896;positive regulation of cellular component organization#GO:0051130;establishment of localization in cell#GO:0051649;positive regulation of autophagy#GO:0010508;intracellular transport#GO:0046907;regulation of autophagosome maturation#GO:1901096;autophagy#GO:0006914;organelle transport along microtubule#GO:0072384;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;vesicle cytoskeletal trafficking#GO:0099518 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;lytic vacuole#GO:0000323;vesicle#GO:0031982;intracellular organelle#GO:0043229;autophagosome#GO:0005776;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=44164|UniProtKB=A6NF83 A6NF83 NUPR2 PTHR17149:SF3 NUCLEAR PROTEIN 1 AND 2 NUCLEAR PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of cell population proliferation#GO:0008285;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=20276|UniProtKB=Q86XA9 Q86XA9 HEATR5A PTHR21663:SF1 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5A endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 HUMAN|HGNC=20494|UniProtKB=Q5H9T9 Q5H9T9 FSCB PTHR36135:SF1 FIBROUS SHEATH CABYR-BINDING PROTEIN FIBROUS SHEATH CABYR-BINDING PROTEIN HUMAN|HGNC=31252|UniProtKB=Q8NH04 Q8NH04 OR2T27 PTHR26453:SF78 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T27-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=18857|UniProtKB=Q9HCS2 Q9HCS2 CYP4F12 PTHR24291:SF27 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F12 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497 long-chain fatty acid metabolic process#GO:0001676;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid derivative metabolic process#GO:1901568;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 oxygenase#PC00177 HUMAN|HGNC=21051|UniProtKB=Q9UGC7 Q9UGC7 MTRF1L PTHR43804:SF3 LD18447P PEPTIDE CHAIN RELEASE FACTOR 1-LIKE, MITOCHONDRIAL cellular protein complex disassembly#GO:0043624;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;translational termination#GO:0006415;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;mitochondrial translation#GO:0032543;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 translation release factor#PC00225 HUMAN|HGNC=22997|UniProtKB=Q8N8U3 Q8N8U3 RTL3 PTHR15503:SF7 LDOC1 RELATED RETROTRANSPOSON GAG-LIKE PROTEIN 3 HUMAN|HGNC=51235|UniProtKB=B7ZW38 B7ZW38 HNRNPCL3 PTHR13968:SF30 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN C-LIKE 3-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=3318|UniProtKB=P78545 P78545 ELF3 PTHR11849:SF13 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=7806|UniProtKB=Q13952 Q13952 NFYC PTHR10252:SF91 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=11610|UniProtKB=O15273 O15273 TCAP PTHR15143:SF0 TELETHONIN TELETHONIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;structural molecule activity#GO:0005198;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;system process#GO:0003008;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;skeletal muscle contraction#GO:0003009;cytoskeleton organization#GO:0007010;response to abiotic stimulus#GO:0009628;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;circulatory system development#GO:0072359;heart contraction#GO:0060047;cardiac muscle tissue development#GO:0048738;detection of stimulus#GO:0051606;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;cardiac muscle cell development#GO:0055013;muscle tissue development#GO:0060537;cellular component organization or biogenesis#GO:0071840;response to mechanical stimulus#GO:0009612;cardiocyte differentiation#GO:0035051;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;blood circulation#GO:0008015;heart development#GO:0007507;muscle organ development#GO:0007517;detection of mechanical stimulus#GO:0050982;animal organ development#GO:0048513;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;system development#GO:0048731;striated muscle tissue development#GO:0014706;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;heart morphogenesis#GO:0003007;cellular component assembly involved in morphogenesis#GO:0010927;cardiac muscle contraction#GO:0060048;multicellular organism development#GO:0007275;cellular process#GO:0009987;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;organelle organization#GO:0006996;animal organ morphogenesis#GO:0009887;tissue morphogenesis#GO:0048729;actin cytoskeleton organization#GO:0030036;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;Z disc#GO:0030018;intracellular#GO:0005622;sarcomere#GO:0030017;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;I band#GO:0031674 HUMAN|HGNC=9188|UniProtKB=P30876 P30876 POLR2B PTHR20856:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=29404|UniProtKB=Q96CT2 Q96CT2 KLHL29 PTHR24412:SF10 KELCH PROTEIN KELCH-LIKE PROTEIN 29 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29153|UniProtKB=Q8TBE0 Q8TBE0 BAHD1 PTHR46576:SF1 BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN HUMAN|HGNC=7869|UniProtKB=O60936 O60936 NOL3 PTHR22797:SF37 CARD6/NUCLEOLAR PROTEIN 3 NUCLEOLAR PROTEIN 3 HUMAN|HGNC=9704|UniProtKB=P20472 P20472 PVALB PTHR11653:SF2 PARVALBUMIN ALPHA PARVALBUMIN ALPHA cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 calmodulin-related#PC00061 HUMAN|HGNC=6447|UniProtKB=P35527 P35527 KRT9 PTHR23239:SF96 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 9 HUMAN|HGNC=25931|UniProtKB=Q0VF96 Q0VF96 CGNL1 PTHR46349:SF2 CINGULIN-LIKE PROTEIN 1-RELATED CINGULIN-LIKE PROTEIN 1 HUMAN|HGNC=29041|UniProtKB=Q9UJP4 Q9UJP4 KLHL21 PTHR24412:SF255 KELCH PROTEIN KELCH-LIKE PROTEIN 21 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25005|UniProtKB=Q9P031 Q9P031 CCDC59 PTHR15657:SF1 UNCHARACTERIZED THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=18503|UniProtKB=Q9BYV7 Q9BYV7 BCO2 PTHR10543:SF122 BETA-CAROTENE DIOXYGENASE BETA,BETA-CAROTENE 9',10'-OXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=18336|UniProtKB=Q53EQ6 Q53EQ6 TIGD5 PTHR19303:SF56 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 HUMAN|HGNC=30589|UniProtKB=Q9BQS6 Q9BQS6 HSPB9 PTHR47896:SF1 HEAT SHOCK PROTEIN BETA-9 HEAT SHOCK PROTEIN BETA-9 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3798|UniProtKB=P15408 P15408 FOSL2 PTHR23351:SF25 FOS TRANSCRIPTION FACTOR-RELATED FOS-RELATED ANTIGEN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=18904|UniProtKB=P0C5Y4 P0C5Y4 KRTAP1-4 PTHR23262:SF186 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 1-4 HUMAN|HGNC=18981|UniProtKB=Q8N165 Q8N165 PDIK1L PTHR11042:SF58 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED SERINE/THREONINE-PROTEIN KINASE PDIK1L transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=18171|UniProtKB=Q9BZW8 Q9BZW8 CD244 PTHR12080:SF56 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE NATURAL KILLER CELL RECEPTOR 2B4 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=26703|UniProtKB=Q8N205 Q8N205 SYNE4 PTHR21640:SF1 UNCHARACTERIZED NESPRIN-4 HUMAN|HGNC=12698|UniProtKB=P98155 P98155 VLDLR PTHR24270:SF16 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED VERY LOW-DENSITY LIPOPROTEIN RECEPTOR apolipoprotein#PC00052 HUMAN|HGNC=13221|UniProtKB=Q9H165 Q9H165 BCL11A PTHR45993:SF5 B-CELL LYMPHOMA/LEUKEMIA 11 B-CELL LYMPHOMA/LEUKEMIA 11A cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;dendrite development#GO:0016358;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;negative regulation of cellular component organization#GO:0051129;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;primary metabolic process#GO:0044238;regulation of neuron projection development#GO:0010975;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;aromatic compound biosynthetic process#GO:0019438;neuron development#GO:0048666;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=37162|UniProtKB=P0CJ72 P0CJ72 MTRNR2L5 PTHR33895:SF4 HUMANIN-LIKE 4 HUMANIN-LIKE 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=23506|UniProtKB=Q96SZ5 Q96SZ5 ADO PTHR22966:SF61 UNCHARACTERIZED 2-AMINOETHANETHIOL DIOXYGENASE HUMAN|HGNC=21345|UniProtKB=Q6ZW05 Q6ZW05 PTCHD4 PTHR10796:SF15 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 4 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 HUMAN|HGNC=1391|UniProtKB=Q01668 Q01668 CACNA1D PTHR45628:SF11 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1D calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812;calcium ion transport#GO:0006816 voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096 HUMAN|HGNC=989|UniProtKB=O95999 O95999 BCL10 PTHR34920:SF1 B-CELL LYMPHOMA/LEUKEMIA 10 B-CELL LYMPHOMA/LEUKEMIA 10 binding#GO:0005488;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;transcription factor binding#GO:0008134;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;DNA-binding transcription factor binding#GO:0140297;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transferase activity#GO:0016740;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of apoptotic signaling pathway#GO:2001233;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;adaptive immune response#GO:0002250;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;positive regulation of programmed cell death#GO:0043068;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;cell death#GO:0008219;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;signaling#GO:0023052;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;nucleic acid-templated transcription#GO:0097659;positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of cell death#GO:0010942;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=572|UniProtKB=Q9Y6B7 Q9Y6B7 AP4B1 PTHR11134:SF4 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-4 COMPLEX SUBUNIT BETA-1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane traffic protein#PC00150 HUMAN|HGNC=9891|UniProtKB=Q99708 Q99708 RBBP8 PTHR15107:SF4 RETINOBLASTOMA BINDING PROTEIN 8 DNA ENDONUCLEASE RBBP8 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;single-stranded DNA binding#GO:0003697;endonuclease activity#GO:0004519;damaged DNA binding#GO:0003684;double-stranded DNA binding#GO:0003690;deoxyribonuclease activity#GO:0004536;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;endodeoxyribonuclease activity#GO:0004520 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;DNA double-strand break processing#GO:0000729;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;site of double-strand break#GO:0035861;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 HUMAN|HGNC=12284|UniProtKB=A0A0A0MS02 A0A0A0MS02 TRGV1 PTHR19256:SF48 T-CELL RECEPTOR GAMMA CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=9379|UniProtKB=O43741 O43741 PRKAB2 PTHR10343:SF84 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 HUMAN|HGNC=1919|UniProtKB=Q14839 Q14839 CHD4 PTHR45623:SF22 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 4 HUMAN|HGNC=1297|UniProtKB=Q9NX36 Q9NX36 DNAJC28 PTHR24016:SF12 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 DNAJ HOMOLOG SUBFAMILY C MEMBER 28 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;Golgi organization#GO:0007030;transport#GO:0006810;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein-containing complex subunit organization#GO:0043933 intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;Golgi transport complex#GO:0017119;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=25373|UniProtKB=Q9H0Q0 Q9H0Q0 CYRIA PTHR12422:SF4 UNCHARACTERIZED CYFIP-RELATED RAC1 INTERACTOR A HUMAN|HGNC=19123|UniProtKB=Q8WXX5 Q8WXX5 DNAJC9 PTHR44144:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=23297|UniProtKB=Q96SI1 Q96SI1 KCTD15 PTHR14499:SF27 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD15 scaffold/adaptor protein#PC00226 HUMAN|HGNC=14315|UniProtKB=O60667 O60667 FCMR PTHR11860:SF59 POLYMERIC-IMMUNOGLOBULIN RECEPTOR FAS APOPTOTIC INHIBITORY MOLECULE 3 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=9554|UniProtKB=Q99460 Q99460 PSMD1 PTHR10943:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;proteasome regulatory particle, base subcomplex#GO:0008540;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 HUMAN|HGNC=28304|UniProtKB=Q96EC8 Q96EC8 YIPF6 PTHR21236:SF1 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF6 HUMAN|HGNC=29629|UniProtKB=P41223 P41223 BUD31 PTHR19411:SF0 PROTEIN BUD31-RELATED PROTEIN BUD31 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=14249|UniProtKB=Q9NRE1 Q9NRE1 MMP26 PTHR10201:SF76 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-26 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 HUMAN|HGNC=11749|UniProtKB=Q14186 Q14186 TFDP1 PTHR12548:SF4 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP-1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=24546|UniProtKB=Q96F85 Q96F85 CNRIP1 PTHR31952:SF1 CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1 CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signaling#GO:0023052;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=10310|UniProtKB=Q07020 Q07020 RPL18 PTHR10934:SF6 60S RIBOSOMAL PROTEIN L18 60S RIBOSOMAL PROTEIN L18 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=7714|UniProtKB=O75251 O75251 NDUFS7 PTHR11995:SF22 NADH DEHYDROGENASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;monovalent inorganic cation transport#GO:0015672;mitochondrial respiratory chain complex assembly#GO:0033108;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;ion transport#GO:0006811;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;protein-containing complex assembly#GO:0065003;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;energy derivation by oxidation of organic compounds#GO:0015980;cation transmembrane transport#GO:0098655;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitochondrial respiratory chain complex I assembly#GO:0032981;establishment of localization#GO:0051234;organelle organization#GO:0006996;oxidation-reduction process#GO:0055114;mitochondrion organization#GO:0007005;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152 mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;mitochondrial respiratory chain complex I#GO:0005747;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;plasma membrane respiratory chain complex I#GO:0045272;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;catalytic complex#GO:1902494;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964;plasma membrane#GO:0005886 dehydrogenase#PC00092 HUMAN|HGNC=29578|UniProtKB=Q6IQ19 Q6IQ19 CCSAP PTHR31022:SF4 UNCHARACTERIZED CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;regulation of mitotic nuclear division#GO:0007088;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;regulation of mitotic spindle organization#GO:0060236;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;regulation of cellular component biogenesis#GO:0044087;mitotic spindle assembly#GO:0090307;regulation of microtubule cytoskeleton organization#GO:0070507;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;spindle organization#GO:0007051;cellular component assembly#GO:0022607;regulation of nuclear division#GO:0051783;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of mitotic cell cycle#GO:0007346 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;spindle#GO:0005819;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=7512|UniProtKB=Q02817 Q02817 MUC2 PTHR11339:SF391 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-2 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=30162|UniProtKB=Q2M3D2 Q2M3D2 EXOC3L2 PTHR21292:SF7 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;vesicle organization#GO:0016050;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 membrane traffic protein#PC00150 HUMAN|HGNC=2926|UniProtKB=Q9UGM3 Q9UGM3 DMBT1 PTHR19331:SF22 SCAVENGER RECEPTOR DOMAIN-CONTAINING DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN serine protease#PC00203 Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=10812|UniProtKB=Q96BR1 Q96BR1 SGK3 PTHR24356:SF121 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE SGK3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=20106|UniProtKB=Q8N966 Q8N966 ZDHHC22 PTHR22883:SF213 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC22 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=4638|UniProtKB=P09211 P09211 GSTP1 PTHR11571:SF255 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE P transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transferase#PC00220 HUMAN|HGNC=4531|UniProtKB=Q96P68 Q96P68 OXGR1 PTHR24231:SF15 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 2-OXOGLUTARATE RECEPTOR 1 G-protein coupled receptor#PC00021 HUMAN|HGNC=17224|UniProtKB=O75154 O75154 RAB11FIP3 PTHR15726:SF6 RAB11-FAMILY INTERACTING PROTEIN RAB11 FAMILY-INTERACTING PROTEIN 3 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 endosomal transport#GO:0016197;cellular localization#GO:0051641;cell division#GO:0051301;membrane fission#GO:0090148;membrane organization#GO:0061024;transport#GO:0006810;cell cycle process#GO:0022402;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cell division#GO:0051302;regulation of cell cycle process#GO:0010564;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of cytokinesis#GO:0032465;cytokinesis#GO:0000910 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;centrosome#GO:0005813;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;recycling endosome#GO:0055037;plasma membrane region#GO:0098590;cell division site#GO:0032153;microtubule organizing center#GO:0005815;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;centriole#GO:0005814;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=19989|UniProtKB=Q9UJX6 Q9UJX6 ANAPC2 PTHR45957:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear ubiquitin ligase complex#GO:0000152 Cell cycle#P00013>APC#P00481 HUMAN|HGNC=25024|UniProtKB=Q9HBI5 Q9HBI5 C3orf14 PTHR14286:SF2 GENE, 49355-RELATED RGD1306063 PROTEIN HUMAN|HGNC=9247|UniProtKB=O75145 O75145 PPFIA3 PTHR12587:SF4 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-3 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 HUMAN|HGNC=1211|UniProtKB=Q5XX13 Q5XX13 FBXW10 PTHR19872:SF7 UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN CMT1A DUPLICATED REGION TRANSCRIPT 1 PROTEIN-RELATED ubiquitin-protein ligase#PC00234 HUMAN|HGNC=5395|UniProtKB=Q16666 Q16666 IFI16 PTHR12200:SF5 INTERFERON-INDUCIBLE PROTEIN AIM2 FAMILY MEMBER GAMMA-INTERFERON-INDUCIBLE PROTEIN 16 heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;activation of immune response#GO:0002253;response to cytokine#GO:0034097;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;positive regulation of metabolic process#GO:0009893;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;defense response to other organism#GO:0098542;response to chemical#GO:0042221;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of defense response#GO:0031347;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=24257|UniProtKB=Q9HC24 Q9HC24 TMBIM4 PTHR23291:SF50 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 4 HUMAN|HGNC=17883|UniProtKB=Q8NFT6 Q8NFT6 DBF4B PTHR15375:SF24 ACTIVATOR OF S-PHASE KINASE-RELATED PROTEIN DBF4 HOMOLOG B protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 cellular aromatic compound metabolic process#GO:0006725;positive regulation of DNA replication#GO:0045740;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of cell cycle process#GO:0090068;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear DNA replication#GO:0033260;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;regulation of cell cycle#GO:0051726;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase activator#PC00138 HUMAN|HGNC=15807|UniProtKB=Q9H4Z2 Q9H4Z2 ZNF335 PTHR24403:SF36 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 335 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;organic cyclic compound binding#GO:0097159;binding#GO:0005488;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;gene expression#GO:0010467;histone methylation#GO:0016571;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein alkylation#GO:0008213;transcription, DNA-templated#GO:0006351;protein methylation#GO:0006479;nitrogen compound metabolic process#GO:0006807;histone H3-K4 methylation#GO:0051568;regulation of chromatin organization#GO:1902275;central nervous system development#GO:0007417;positive regulation of cell development#GO:0010720;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of neurogenesis#GO:0050769;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;peptidyl-lysine trimethylation#GO:0018023;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;head development#GO:0060322;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of histone modification#GO:0031056;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;peptidyl-lysine methylation#GO:0018022;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;histone lysine methylation#GO:0034968;positive regulation of nervous system development#GO:0051962;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of developmental process#GO:0051094;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13444|UniProtKB=O95528 O95528 SLC2A10 PTHR48023:SF7 D-XYLOSE-PROTON SYMPORTER-LIKE 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 10 HUMAN|HGNC=8616|UniProtKB=Q02962 Q02962 PAX2 PTHR45636:SF19 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=28689|UniProtKB=Q8N4M1 Q8N4M1 SLC44A3 PTHR12385:SF13 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098 HUMAN|HGNC=29954|UniProtKB=Q8NAP1 Q8NAP1 CASTOR3 PTHR31131:SF2 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 2-RELATED signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;TORC1 signaling#GO:0038202;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=6173|UniProtKB=O43736 O43736 ITM2A PTHR10962:SF7 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2A amyloid-beta binding#GO:0001540;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 glycoprotein biosynthetic process#GO:0009101;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;carbohydrate derivative metabolic process#GO:1901135;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;carbohydrate derivative biosynthetic process#GO:1901137;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=2170|UniProtKB=P26992 P26992 CNTFR PTHR23036:SF21 CYTOKINE RECEPTOR CILIARY NEUROTROPHIC FACTOR RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=43621|UniProtKB=A0A1W2PQD8 A0A1W2PQD8 SSU72P2 PTHR20383:SF10 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;mRNA 3'-end processing#GO:0031124;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;mRNA polyadenylation#GO:0006378;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;dephosphorylation#GO:0016311;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 protein phosphatase#PC00195 HUMAN|HGNC=17295|UniProtKB=Q8N1P7 Q8N1P7 CRYBG2 PTHR11818:SF50 BETA/GAMMA CRYSTALLIN BETA/GAMMA CRYSTALLIN DOMAIN-CONTAINING PROTEIN 2 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=11744|UniProtKB=Q92754 Q92754 TFAP2C PTHR10812:SF9 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2 GAMMA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 general transcription factor#PC00259 HUMAN|HGNC=2558|UniProtKB=P49238 P49238 CX3CR1 PTHR10489:SF637 CELL ADHESION MOLECULE CX3C CHEMOKINE RECEPTOR 1 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=4287|UniProtKB=O95377 O95377 GJB5 PTHR11984:SF29 CONNEXIN GAP JUNCTION BETA-5 PROTEIN gap junction#PC00105 HUMAN|HGNC=12116|UniProtKB=A0A0B4J234 A0A0B4J234 TRAV2 PTHR23267:SF374 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 2 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=16348|UniProtKB=Q8IWW6 Q8IWW6 ARHGAP12 PTHR23176:SF107 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 12 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=23179|UniProtKB=Q86XN6 Q86XN6 ZNF761 PTHR24377:SF825 IP01015P-RELATED ZINC FINGER PROTEIN 761 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=17700|UniProtKB=Q9NRJ3 Q9NRJ3 CCL28 PTHR17502:SF2 C-C MOTIF CHEMOKINE 27 FAMILY MEMBER C-C MOTIF CHEMOKINE 28 binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;molecular function regulator#GO:0098772;protein binding#GO:0005515;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;chemokine receptor binding#GO:0042379;cytokine receptor binding#GO:0005126 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=30794|UniProtKB=Q86XR8 Q86XR8 CEP57 PTHR19336:SF11 UNCHARACTERIZED DUF1167 CENTROSOMAL PROTEIN OF 57 KDA cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=9479|UniProtKB=P36776 P36776 LONP1 PTHR43718:SF2 LON PROTEASE LON PROTEASE HOMOLOG, MITOCHONDRIAL pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;ATPase activity#GO:0016887 macromolecule catabolic process#GO:0009057;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 serine protease#PC00203 HUMAN|HGNC=14405|UniProtKB=Q9NQT8 Q9NQT8 KIF13B PTHR24115:SF338 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF13B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=25468|UniProtKB=Q9H900 Q9H900 ZWILCH PTHR15995:SF1 PROTEIN ZWILCH HOMOLOG PROTEIN ZWILCH HOMOLOG HUMAN|HGNC=23386|UniProtKB=O75592 O75592 MYCBP2 PTHR45943:SF1 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=28387|UniProtKB=Q96KX0 Q96KX0 LYZL4 PTHR11407:SF21 LYSOZYME C LYSOZYME-LIKE PROTEIN 4 plasma membrane fusion#GO:0045026;fertilization#GO:0009566;membrane organization#GO:0061024;multicellular organism reproduction#GO:0032504;cellular process involved in reproduction in multicellular organism#GO:0022412;single fertilization#GO:0007338;cellular component organization#GO:0016043;cellular process#GO:0009987;multi-organism process#GO:0051704;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;reproduction#GO:0000003;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703 supramolecular complex#GO:0099080;axoneme#GO:0005930;acrosomal vesicle#GO:0001669;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;cytoplasmic microtubule#GO:0005881;vacuole#GO:0005773;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;B axonemal microtubule#GO:0097650;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;intracellular vesicle#GO:0097708;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;cytoplasmic vesicle#GO:0031410;dynein complex#GO:0030286;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 HUMAN|HGNC=33875|UniProtKB=Q6ZT77 Q6ZT77 ZNF826P PTHR24384:SF95 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 486-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=16167|UniProtKB=Q5JPB2 Q5JPB2 ZNF831 PTHR47166:SF1 ZINC FINGER PROTEIN 831 ZINC FINGER PROTEIN 831 HUMAN|HGNC=4684|UniProtKB=P33402 P33402 GUCY1A2 PTHR45655:SF7 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT ALPHA-2 guanylate cyclase#PC00114 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 HUMAN|HGNC=783|UniProtKB=P18846 P18846 ATF1 PTHR45879:SF2 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Apoptosis signaling pathway#P00006>ATF#P00302;p38 MAPK pathway#P05918>ATF1#P06019 HUMAN|HGNC=15223|UniProtKB=Q8NGK3 Q8NGK3 OR52K2 PTHR26450:SF404 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52K2 transmembrane signal receptor#PC00197 HUMAN|HGNC=25862|UniProtKB=Q9BSC4 Q9BSC4 NOL10 PTHR14927:SF0 UNCHARACTERIZED NUCLEOLAR PROTEIN 10 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 HUMAN|HGNC=870|UniProtKB=P35670 P35670 ATP7B PTHR43520:SF9 ATP7, ISOFORM B COPPER-TRANSPORTING ATPASE 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 trans-Golgi network#GO:0005802;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=5420|UniProtKB=P01570 P01570 IFNA14 PTHR11691:SF67 TYPE I INTERFERON INTERFERON ALPHA-14 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=31419|UniProtKB=Q5T9C2 Q5T9C2 FAM102A PTHR21456:SF2 FAMILY WITH SEQUENCE SIMILARITY 102 PROTEIN FAM102A HUMAN|HGNC=1653|UniProtKB=P10747 P10747 CD28 PTHR11494:SF7 CYTOTOXIC T-LYMPHOCYTE PROTEIN T-CELL-SPECIFIC SURFACE GLYCOPROTEIN CD28 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of biological process#GO:0048518;signaling#GO:0023052;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>CD28#P01313 HUMAN|HGNC=14435|UniProtKB=Q8N187 Q8N187 CARF PTHR14694:SF1 CALCIUM-RESPONSIVE TRANSCRIPTION FACTOR CALCIUM-RESPONSIVE TRANSCRIPTION FACTOR DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;response to inorganic substance#GO:0010035;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;response to metal ion#GO:0010038;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=24986|UniProtKB=Q7Z6W7 Q7Z6W7 DNAJB7 PTHR43948:SF4 FAMILY NOT NAMED DNAJ HOMOLOG SUBFAMILY B MEMBER 7 HUMAN|HGNC=13148|UniProtKB=Q92670 Q92670 ZNF75CP PTHR23226:SF142 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 75C-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1970|UniProtKB=Q9Y4C5 Q9Y4C5 CHST2 PTHR10704:SF3 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=9101|UniProtKB=P51805 P51805 PLXNA3 PTHR22625:SF32 PLEXIN PLEXIN-A3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of GTPase activity#GO:0043087;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of neuron differentiation#GO:0045664;negative regulation of cell adhesion#GO:0007162;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;positive regulation of neuron projection development#GO:0010976;locomotion#GO:0040011;taxis#GO:0042330;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of cell projection organization#GO:0031346;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;biological adhesion#GO:0022610;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of cell adhesion#GO:0030155;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;positive regulation of neuron differentiation#GO:0045666;cellular response to stimulus#GO:0051716;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;cell migration#GO:0016477 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=32961|UniProtKB=Q8N140 Q8N140 EID3 PTHR16140:SF1 UNCHARACTERIZED EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 3 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of response to DNA damage stimulus#GO:2001020;cellular macromolecule metabolic process#GO:0044260;positive regulation of response to DNA damage stimulus#GO:2001022;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=34072|UniProtKB=B2RNN3 B2RNN3 C1QTNF9B PTHR15427:SF21 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q AND TUMOR NECROSIS FACTOR-RELATED PROTEIN 9A-RELATED HUMAN|HGNC=5007|UniProtKB=Q01581 Q01581 HMGCS1 PTHR43323:SF4 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE HYDROXYMETHYLGLUTARYL-COA SYNTHASE, CYTOPLASMIC transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA synthase#P00498 HUMAN|HGNC=3327|UniProtKB=P15502 P15502 ELN PTHR24018:SF5 ELASTIN ELASTIN structural protein#PC00211 HUMAN|HGNC=1157|UniProtKB=Q13895 Q13895 BYSL PTHR12821:SF0 BYSTIN BYSTIN snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 HUMAN|HGNC=28638|UniProtKB=Q7L5L3 Q7L5L3 GDPD3 PTHR42758:SF3 PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C LYSOPHOSPHOLIPASE D GDPD3 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 phospholipase#PC00186 HUMAN|HGNC=20514|UniProtKB=Q8N257 Q8N257 H2BU1 PTHR23428:SF167 HISTONE H2B HISTONE H2B TYPE 3-B nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=26104|UniProtKB=Q9H7E9 Q9H7E9 C8orf33 PTHR13602:SF2 UNCHARACTERIZED UPF0488 PROTEIN C8ORF33 HUMAN|HGNC=17451|UniProtKB=Q9Y271 Q9Y271 CYSLTR1 PTHR24230:SF12 G-PROTEIN COUPLED RECEPTOR CYSTEINYL LEUKOTRIENE RECEPTOR 1 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=15795|UniProtKB=Q9NQ39 Q9NQ39 RPS10P5 PTHR12146:SF8 40S RIBOSOMAL PROTEIN S10 40S RIBOSOMAL PROTEIN S10-LIKE-RELATED structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;ribonucleoprotein complex subunit organization#GO:0071826;ribonucleoprotein complex assembly#GO:0022618;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;ribosome biogenesis#GO:0042254;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=17945|UniProtKB=P81277 P81277 PRLH PTHR17206:SF1 PROLACTIN-RELEASING PEPTIDE PROLACTIN-RELEASING PEPTIDE neuropeptide hormone activity#GO:0005184;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;response to peptide hormone#GO:0043434;behavior#GO:0007610;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to peptide#GO:1901652;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 HUMAN|HGNC=7417|UniProtKB=Q96DY7 Q96DY7 MTBP PTHR14382:SF1 MDM2-BINDING PROTEIN MDM2-BINDING PROTEIN cellular localization#GO:0051641;mitotic cell cycle phase transition#GO:0044772;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;protein localization to kinetochore#GO:0034501;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;mitotic nuclear division#GO:0140014;protein localization to organelle#GO:0033365;regulation of G1/S transition of mitotic cell cycle#GO:2000045;positive regulation of biological process#GO:0048518;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G1/S phase transition#GO:1902806 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular#GO:0005622;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=15992|UniProtKB=Q9BYN7 Q9BYN7 ZNF341 PTHR24388:SF28 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 341 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=10699|UniProtKB=O76054 O76054 SEC14L2 PTHR23324:SF64 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 2 HUMAN|HGNC=29105|UniProtKB=O94827 O94827 PLEKHG5 PTHR13217:SF11 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 5 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;Ras protein signal transduction#GO:0007265;localization of cell#GO:0051674;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;endothelial cell migration#GO:0043542;Rho protein signal transduction#GO:0007266;localization#GO:0051179;small GTPase mediated signal transduction#GO:0007264;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052 intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=37170|UniProtKB=S4R3P1 S4R3P1 MTRNR2L13 PTHR33895:SF17 HUMANIN-LIKE 4 HUMANIN-LIKE 13 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=26961|UniProtKB=Q8NCN4 Q8NCN4 RNF169 PTHR23328:SF2 UNCHARACTERIZED E3 UBIQUITIN-PROTEIN LIGASE RNF169 HUMAN|HGNC=14269|UniProtKB=O43173 O43173 ST8SIA3 PTHR11987:SF36 ALPHA-2,8-SIALYLTRANSFERASE SIA-ALPHA-2,3-GAL-BETA-1,4-GLCNAC-R:ALPHA 2,8-SIALYLTRANSFERASE transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=1667|UniProtKB=P28907 P28907 CD38 PTHR10912:SF5 ADP-RIBOSYL CYCLASE ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 lymphocyte activation#GO:0046649;regulation of cell population proliferation#GO:0042127;positive regulation of cell population proliferation#GO:0008284;positive regulation of immune system process#GO:0002684;B cell proliferation#GO:0042100;lymphocyte proliferation#GO:0046651;cell population proliferation#GO:0008283;cellular process#GO:0009987;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;leukocyte proliferation#GO:0070661;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;regulation of immune system process#GO:0002682;regulation of leukocyte proliferation#GO:0070663;B cell activation#GO:0042113;positive regulation of cell activation#GO:0050867;positive regulation of biological process#GO:0048518;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;regulation of B cell proliferation#GO:0030888;mononuclear cell proliferation#GO:0032943 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079 CCKR signaling map#P06959>CD38#P07204 HUMAN|HGNC=13308|UniProtKB=Q9NZH0 Q9NZH0 GPRC5B PTHR14511:SF9 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER B protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;protein kinase activity#GO:0004672;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 receptor complex#GO:0043235;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=8700|UniProtKB=Q9Y5H1 Q9Y5H1 PCDHGA2 PTHR24028:SF134 CADHERIN-87A PROTOCADHERIN GAMMA-A2 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=24162|UniProtKB=Q9BW30 Q9BW30 TPPP3 PTHR12932:SF16 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;positive regulation of protein polymerization#GO:0032273;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=4507|UniProtKB=O75899 O75899 GABBR2 PTHR10519:SF67 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 HUMAN|HGNC=30361|UniProtKB=Q9BUL9 Q9BUL9 RPP25 PTHR13516:SF5 RIBONUCLEASE P SUBUNIT P25 RIBONUCLEASE P PROTEIN SUBUNIT P25 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 small nucleolar ribonucleoprotein complex#GO:0005732;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;ribonuclease MRP complex#GO:0000172;intracellular#GO:0005622;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 endoribonuclease#PC00094 HUMAN|HGNC=16273|UniProtKB=Q96A49 Q96A49 SYAP1 PTHR16019:SF6 SYNAPSE-ASSOCIATED PROTEIN SYNAPSE-ASSOCIATED PROTEIN 1 HUMAN|HGNC=9950|UniProtKB=O94762 O94762 RECQL5 PTHR13710:SF124 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q5 pyrophosphatase activity#GO:0016462;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA helicase#PC00011 HUMAN|HGNC=797|UniProtKB=Q92858 Q92858 ATOH1 PTHR19290:SF82 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED PROTEIN ATONAL HOMOLOG 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=16831|UniProtKB=O95153 O95153 TSPOAP1 PTHR14234:SF20 RIM BINDING PROTEIN-RELATED PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR-ASSOCIATED PROTEIN 1 chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;neuromuscular synaptic transmission#GO:0007274;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 HUMAN|HGNC=6647|UniProtKB=P29536 P29536 LMOD1 PTHR10901:SF5 TROPOMODULIN LEIOMODIN-1 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=2555|UniProtKB=Q13620 Q13620 CUL4B PTHR11932:SF66 CULLIN CULLIN-4B transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular response to stress#GO:0033554;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=6858|UniProtKB=O95382 O95382 MAP3K6 PTHR11584:SF391 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 6 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>MEKK1-5#P00634 HUMAN|HGNC=16754|UniProtKB=Q96P50 Q96P50 ACAP3 PTHR23180:SF407 CENTAURIN/ARF ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=34452|UniProtKB=A8MTZ7 A8MTZ7 C12orf71 PTHR36462:SF1 CHROMOSOME 12 OPEN READING FRAME 71 CHROMOSOME 12 OPEN READING FRAME 71 HUMAN|HGNC=13490|UniProtKB=Q9Y4E6 Q9Y4E6 WDR7 PTHR44099:SF3 RABCONNECTIN-3B, ISOFORM A WD REPEAT-CONTAINING PROTEIN 7 HUMAN|HGNC=14928|UniProtKB=Q9BZV1 Q9BZV1 UBXN6 PTHR23153:SF38 UBX-RELATED UBX DOMAIN-CONTAINING PROTEIN 6 HUMAN|HGNC=16084|UniProtKB=Q7Z4I7 Q7Z4I7 LIMS2 PTHR24210:SF10 LIM DOMAIN-CONTAINING PROTEIN LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 2 regulation of cell morphogenesis involved in differentiation#GO:0010769;signal transduction#GO:0007165;positive regulation of cell-substrate adhesion#GO:0010811;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of signal transduction#GO:0009967;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;substrate adhesion-dependent cell spreading#GO:0034446;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;integrin-mediated signaling pathway#GO:0007229;regulation of cell adhesion#GO:0030155;positive regulation of cell development#GO:0010720;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cell-cell junction organization#GO:0045216;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;cell junction organization#GO:0034330;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cell adhesion#GO:0045785 cytoplasm#GO:0005737;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 HUMAN|HGNC=29522|UniProtKB=Q99619 Q99619 SPSB2 PTHR12245:SF2 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 2 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=16849|UniProtKB=Q15014 Q15014 MORF4L2 PTHR10880:SF25 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 2 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;histone H4 acetylation#GO:0043967;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;peptidyl-lysine acetylation#GO:0018394;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=10730|UniProtKB=Q9NPR2 Q9NPR2 SEMA4B PTHR11036:SF14 SEMAPHORIN SEMAPHORIN-4B receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=27610|UniProtKB=Q6P5R6 Q6P5R6 RPL22L1 PTHR10064:SF1 60S RIBOSOMAL PROTEIN L22 60S RIBOSOMAL PROTEIN L22-LIKE 1 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribosomal protein#PC00202 HUMAN|HGNC=26235|UniProtKB=Q9H5X1 Q9H5X1 CIAO2A PTHR12377:SF6 UNCHARACTERIZED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2A HUMAN|HGNC=33187|UniProtKB=Q6P582 Q6P582 MZT2A PTHR28578:SF3 MITOTIC-SPINDLE ORGANIZING PROTEIN 2A-RELATED MITOTIC-SPINDLE ORGANIZING PROTEIN 2A intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule organizing center#GO:0005815;intracellular#GO:0005622;gamma-tubulin complex#GO:0000930;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=30792|UniProtKB=O60739 O60739 EIF1B PTHR10388:SF51 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR 1B nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;ribonucleoprotein complex binding#GO:0043021;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 translation initiation factor#PC00224 HUMAN|HGNC=23158|UniProtKB=Q9NPJ4 Q9NPJ4 PNRC2 PTHR15405:SF6 PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR 2 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P-body#GO:0000932;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=10647|UniProtKB=P78423 P78423 CX3CL1 PTHR12015:SF92 SMALL INDUCIBLE CYTOKINE A FRACTALKINE receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=24380|UniProtKB=Q6YFQ2 Q6YFQ2 COX6B2 PTHR11387:SF12 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidase#PC00175 HUMAN|HGNC=20814|UniProtKB=Q9C0F3 Q9C0F3 ZNF436 PTHR24381:SF327 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 436 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7508|UniProtKB=P15941 P15941 MUC1 PTHR10006:SF19 MUCIN-1-RELATED MUCIN-1 cell adhesion molecule#PC00069 HUMAN|HGNC=8778|UniProtKB=Q14432 Q14432 PDE3A PTHR11347:SF104 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;cellular process involved in reproduction in multicellular organism#GO:0022412;negative regulation of intracellular signal transduction#GO:1902532;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of cell differentiation#GO:0045595;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of signal transduction#GO:0009966;reproductive process#GO:0022414;regulation of multi-organism process#GO:0043900;intracellular signal transduction#GO:0035556;positive regulation of cell development#GO:0010720;multi-organism reproductive process#GO:0044703;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;gamete generation#GO:0007276;regulation of multicellular organismal process#GO:0051239;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;multicellular organism reproduction#GO:0032504;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;multi-organism process#GO:0051704;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;reproduction#GO:0000003;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935;positive regulation of multicellular organismal process#GO:0051240 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phosphodiesterase#PC00185 HUMAN|HGNC=19185|UniProtKB=Q86XX4 Q86XX4 FRAS1 PTHR45739:SF1 MATRIX PROTEIN, PUTATIVE-RELATED EXTRACELLULAR MATRIX PROTEIN FRAS1 HUMAN|HGNC=4801|UniProtKB=P40939 P40939 HADHA PTHR43612:SF7 TRIFUNCTIONAL ENZYME SUBUNIT ALPHA TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;oxidoreductase activity#GO:0016491;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3599|UniProtKB=P22087 P22087 FBL PTHR10335:SF4 RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN RRNA 2'-O-METHYLTRANSFERASE FIBRILLARIN N-methyltransferase activity#GO:0008170;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;histone methylation#GO:0016571;protein modification process#GO:0036211;nucleobase-containing compound metabolic process#GO:0006139;protein alkylation#GO:0008213;ncRNA metabolic process#GO:0034660;protein methylation#GO:0006479;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;histone modification#GO:0016570;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;chromatin organization#GO:0006325;RNA methylation#GO:0001510 small nucleolar ribonucleoprotein complex#GO:0005732;membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684 RNA processing factor#PC00147 HUMAN|HGNC=7665|UniProtKB=O43639 O43639 NCK2 PTHR19969:SF12 SH2-SH3 ADAPTOR PROTEIN-RELATED CYTOPLASMIC PROTEIN NCK2 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Nck#P00215;PDGF signaling pathway#P00047>Nck#P01147;T cell activation#P00053>nck#P01314 HUMAN|HGNC=14844|UniProtKB=P0C617 P0C617 OR5AL1 PTHR48018:SF133 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AL1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=2095|UniProtKB=P10909 P10909 CLU PTHR10970:SF1 CLUSTERIN CLUSTERIN CCKR signaling map#P06959>CLU#G06991;CCKR signaling map#P06959>CLU#G07284;CCKR signaling map#P06959>CLU#P07069 HUMAN|HGNC=14902|UniProtKB=Q9NRW1 Q9NRW1 RAB6B PTHR24073:SF343 DRAB5-RELATED RAS-RELATED PROTEIN RAB-6B GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=25515|UniProtKB=Q8TEP8 Q8TEP8 CEP192 PTHR16029:SF11 UNCHARACTERIZED CENTROSOMAL PROTEIN OF 192 KDA HUMAN|HGNC=8651|UniProtKB=P57721 P57721 PCBP3 PTHR10288:SF98 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=26287|UniProtKB=Q5TGP6 Q5TGP6 MROH9 PTHR23120:SF5 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 9 HUMAN|HGNC=28242|UniProtKB=Q96IR7 Q96IR7 HPDL PTHR11959:SF10 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE-LIKE PROTEIN oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;tyrosine metabolic process#GO:0006570;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;aromatic amino acid family metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxygenase#PC00177 HUMAN|HGNC=51831|UniProtKB=P0DN78 P0DN78 OPN1MW3 PTHR24240:SF17 OPSIN MEDIUM-WAVE-SENSITIVE OPSIN 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to abiotic stimulus#GO:0071214;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=26110|UniProtKB=Q9BPY3 Q9BPY3 FAM118B PTHR28623:SF1 PROTEIN FAM118B PROTEIN FAM118B HUMAN|HGNC=21192|UniProtKB=Q9H0C1 Q9H0C1 ZMYND12 PTHR46533:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12 HUMAN|HGNC=40041|UniProtKB=C9J6K1 C9J6K1 C19orf81 PTHR37153:SF1 CHROMOSOME 19 C19ORF81 HOMOLOG CHROMOSOME 19 C19ORF81 HOMOLOG HUMAN|HGNC=10789|UniProtKB=Q16629 Q16629 SRSF7 PTHR23147:SF189 SERINE/ARGININE RICH SPLICING FACTOR SERINE/ARGININE-RICH SPLICING FACTOR 7 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=25319|UniProtKB=Q9H0C2 Q9H0C2 SLC25A31 PTHR45635:SF7 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP/ATP TRANSLOCASE 4 carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organophosphate ester transmembrane transporter activity#GO:0015605;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;purine nucleotide transmembrane transporter activity#GO:0015216;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ATP transmembrane transporter activity#GO:0005347;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide transmembrane transporter activity#GO:0015215;active ion transmembrane transporter activity#GO:0022853 transfer/carrier protein#PC00219 HUMAN|HGNC=30343|UniProtKB=O75165 O75165 DNAJC13 PTHR36983:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=41978|UniProtKB=F8WFD2 F8WFD2 NPIPA3 PTHR15438:SF14 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER A1-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18308|UniProtKB=Q9NVH6 Q9NVH6 TMLHE PTHR10696:SF21 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL hydroxylase#PC00122 HUMAN|HGNC=6932|UniProtKB=P32245 P32245 MC4R PTHR22750:SF6 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 4 signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=18156|UniProtKB=Q8WXI4 Q8WXI4 ACOT11 PTHR11049:SF1 ACYL COENZYME A THIOESTER HYDROLASE ACYL-COENZYME A THIOESTERASE 11 hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;thiolester hydrolase activity#GO:0016790;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982 esterase#PC00097 HUMAN|HGNC=5320|UniProtKB=Q12794 Q12794 HYAL1 PTHR11769:SF23 HYALURONIDASE HYALURONIDASE-1 glycosidase#PC00110 HUMAN|HGNC=10420|UniProtKB=P23396 P23396 RPS3 PTHR11760:SF36 30S/40S RIBOSOMAL PROTEIN S3 40S RIBOSOMAL PROTEIN S3 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of signaling#GO:0023056;positive regulation of cell death#GO:0010942;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of programmed cell death#GO:0043067 cytosolic ribosome#GO:0022626;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=34075|UniProtKB=A8MXV6 A8MXV6 CDRT15L2 PTHR16471:SF0 CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN-LIKE PROTEIN CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN-LIKE PROTEIN HUMAN|HGNC=21238|UniProtKB=Q8N7C4 Q8N7C4 TMEM217 PTHR34928:SF2 TRANSMEMBRANE PROTEIN 217 TRANSMEMBRANE PROTEIN 217 HUMAN|HGNC=11723|UniProtKB=P55061 P55061 TMBIM6 PTHR23291:SF32 BAX INHIBITOR-RELATED BAX INHIBITOR 1 Apoptosis signaling pathway#P00006>Bi1#P00277 HUMAN|HGNC=3672|UniProtKB=O43320 O43320 FGF16 PTHR11486:SF27 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 16 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;positive regulation of cellular component movement#GO:0051272;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of cellular response to growth factor stimulus#GO:0090287;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;endothelial cell migration#GO:0043542;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=25009|UniProtKB=Q9NPD8 Q9NPD8 UBE2T PTHR24068:SF159 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 T ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=14468|UniProtKB=Q96RN1 Q96RN1 SLC26A8 PTHR11814:SF11 SULFATE TRANSPORTER TESTIS ANION TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;inorganic anion transmembrane transporter activity#GO:0015103;active ion transmembrane transporter activity#GO:0022853 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=13389|UniProtKB=Q14112 Q14112 NID2 PTHR12352:SF3 SECRETED MODULAR CALCIUM-BINDING PROTEIN NIDOGEN-2 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;biological adhesion#GO:0022610 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576 calmodulin-related#PC00061 HUMAN|HGNC=6128|UniProtKB=O14654 O14654 IRS4 PTHR10614:SF2 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 4 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759 HUMAN|HGNC=9944|UniProtKB=P35241 P35241 RDX PTHR23281:SF14 MERLIN/MOESIN/EZRIN/RADIXIN RADIXIN actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=281|UniProtKB=P08913 P08913 ADRA2A PTHR24248:SF24 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2A ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 HUMAN|HGNC=4383|UniProtKB=P30679 P30679 GNA15 PTHR10218:SF217 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-15 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 positive regulation of lipase activity#GO:0060193;regulation of adenylate cyclase activity#GO:0045761;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;action potential#GO:0001508;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;dopamine receptor signaling pathway#GO:0007212;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of phospholipase C activity#GO:1900274;regulation of membrane potential#GO:0042391;positive regulation of phospholipase activity#GO:0010518;trans-synaptic signaling#GO:0099537;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117 Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Wnt signaling pathway#P00057>Galpha#P01451;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732 HUMAN|HGNC=23099|UniProtKB=Q8N7R0 Q8N7R0 NANOGP1 PTHR24327:SF72 HOMEOBOX PROTEIN HOMEOBOX PROTEIN NANOG2-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=15830|UniProtKB=Q8N2R0 Q8N2R0 OSR2 PTHR14196:SF4 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED-RELATED 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;urogenital system development#GO:0001655;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=11465|UniProtKB=Q9Y5B9 Q9Y5B9 SUPT16H PTHR13980:SF17 CDC68 RELATED FACT COMPLEX SUBUNIT SPT16 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;DNA replication-independent nucleosome organization#GO:0034724;protein-DNA complex subunit organization#GO:0071824;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of transcription elongation from RNA polymerase II promoter#GO:0032968;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of DNA-templated transcription, elongation#GO:0032784;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of transcription elongation from RNA polymerase II promoter#GO:0034243;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;transcription elongation from RNA polymerase II promoter#GO:0006368;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=3177|UniProtKB=P20800 P20800 EDN2 PTHR13874:SF9 ENDOTHELIN ENDOTHELIN-2 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 blood circulation#GO:0008015;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;system process#GO:0003008;positive regulation of molecular function#GO:0044093;regulation of blood vessel diameter#GO:0097746;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;oxidation-reduction process#GO:0055114;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;regulation of anatomical structure size#GO:0090066;cellular cation homeostasis#GO:0030003;positive regulation of catalytic activity#GO:0043085;smooth muscle contraction#GO:0006939;homeostatic process#GO:0042592;regulation of systemic arterial blood pressure#GO:0003073;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;circulatory system process#GO:0003013;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065;regulation of metabolic process#GO:0019222;muscle system process#GO:0003012;muscle contraction#GO:0006936 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 Endothelin signaling pathway#P00019>ET1-4#P00588;Endothelin signaling pathway#P00019>Pro ET1-4#P00571;Endothelin signaling pathway#P00019>Pre-pro ET1-4#P00576;Endothelin signaling pathway#P00019>Big ET1-4#P00574 HUMAN|Ensembl=ENSG00000274109|UniProtKB=A0A0G2JNQ3 A0A0G2JNQ3 HNRNPCL2 PTHR13968:SF17 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN C-LIKE 1-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=30418|UniProtKB=Q5HYK7 Q5HYK7 SH3D19 PTHR14167:SF48 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING PROTEIN 19 HUMAN|HGNC=14058|UniProtKB=Q8N6W0 Q8N6W0 CELF5 PTHR24012:SF728 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 5 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9673|UniProtKB=Q12913 Q12913 PTPRJ PTHR19134:SF211 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ETA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of MAP kinase activity#GO:0043407;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 protein phosphatase#PC00195 HUMAN|HGNC=10317|UniProtKB=P62750 P62750 RPL23A PTHR11620:SF60 60S RIBOSOMAL PROTEIN L23A 60S RIBOSOMAL PROTEIN L23A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=26288|UniProtKB=Q6NUN7 Q6NUN7 JHY PTHR14726:SF1 UNCHARACTERIZED JHY PROTEIN HOMOLOG vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 HUMAN|HGNC=15215|UniProtKB=Q96RD3 Q96RD3 OR52E6 PTHR26450:SF175 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E6 transmembrane signal receptor#PC00197 HUMAN|HGNC=2651|UniProtKB=P22680 P22680 CYP7A1 PTHR24304:SF1 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 7A1 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 organic acid biosynthetic process#GO:0016053;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;cholesterol homeostasis#GO:0042632;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;steroid biosynthetic process#GO:0006694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 oxygenase#PC00177 HUMAN|HGNC=21640|UniProtKB=O75954 O75954 TSPAN9 PTHR19282:SF41 TETRASPANIN TETRASPANIN-9 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=18509|UniProtKB=Q96LA6 Q96LA6 FCRL1 PTHR11481:SF92 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=25057|UniProtKB=Q96GI7 Q96GI7 FAM89A PTHR46949:SF3 LEUCINE REPEAT ADAPTER PROTEIN 25 PROTEIN FAM89A scaffold/adaptor protein#PC00226 HUMAN|HGNC=25470|UniProtKB=Q5VX71 Q5VX71 SUSD4 PTHR47007:SF1 SUSHI DOMAIN-CONTAINING PROTEIN 4 SUSHI DOMAIN-CONTAINING PROTEIN 4 response to external biotic stimulus#GO:0043207;negative regulation of biological process#GO:0048519;activation of immune response#GO:0002253;humoral immune response#GO:0006959;lymphocyte mediated immunity#GO:0002449;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;adaptive immune response#GO:0002250;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of lymphocyte mediated immunity#GO:0002706;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;defense response#GO:0006952;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;regulation of innate immune response#GO:0045088;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of immune effector process#GO:0002697;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of complement activation#GO:0030449;regulation of defense response#GO:0031347;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;negative regulation of response to external stimulus#GO:0032102;negative regulation of immune system process#GO:0002683;complement activation#GO:0006956 HUMAN|HGNC=6058|UniProtKB=Q9NQS7 Q9NQS7 INCENP PTHR13142:SF1 INNER CENTROMERE PROTEIN INNER CENTROMERE PROTEIN HUMAN|HGNC=7820|UniProtKB=Q6T4R5 Q6T4R5 NHS PTHR23039:SF5 NANCE-HORAN SYNDROME PROTEIN NANCE-HORAN SYNDROME PROTEIN cellular developmental process#GO:0048869;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;developmental process#GO:0032502;lens development in camera-type eye#GO:0002088;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;visual system development#GO:0150063;sensory system development#GO:0048880;cellular process#GO:0009987;sensory organ development#GO:0007423 HUMAN|HGNC=29352|UniProtKB=Q6P9B9 Q6P9B9 INTS5 PTHR31697:SF2 INTEGRATOR COMPLEX SUBUNIT 5 INTEGRATOR COMPLEX SUBUNIT 5 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 HUMAN|HGNC=4422|UniProtKB=P15586 P15586 GNS PTHR43108:SF5 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-ACETYLGLUCOSAMINE-6-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=21650|UniProtKB=Q7Z5Y6 Q7Z5Y6 BMP8A PTHR11848:SF119 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 8A-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=1458|UniProtKB=O43852 O43852 CALU PTHR10827:SF76 RETICULOCALBIN CALUMENIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 calmodulin-related#PC00061 HUMAN|HGNC=19316|UniProtKB=Q32P28 Q32P28 P3H1 PTHR14049:SF5 LEPRECAN 1 PROLYL 3-HYDROXYLASE 1 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=30894|UniProtKB=Q765I0 Q765I0 UTS2B PTHR36876:SF1 UROTENSIN-2B UROTENSIN-2B HUMAN|HGNC=40034|UniProtKB=A6NJW4 A6NJW4 LRRC3C PTHR24373:SF266 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 3C extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=13732|UniProtKB=Q9NNZ6 Q9NNZ6 PRM3 PTHR14317:SF0 SPERM PROTAMINE P3 PROTAMINE-3 microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;sperm motility#GO:0097722;cell motility#GO:0048870;cellular process#GO:0009987;cilium movement involved in cell motility#GO:0060294;cilium movement#GO:0003341;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;reproduction#GO:0000003;microtubule-based process#GO:0007017;reproductive process#GO:0022414;movement of cell or subcellular component#GO:0006928;flagellated sperm motility#GO:0030317;locomotion#GO:0040011 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 histone#PC00118 HUMAN|HGNC=29180|UniProtKB=Q9UPV7 Q9UPV7 PHF24 PTHR10891:SF889 EF-HAND CALCIUM-BINDING DOMAIN CONTAINING PROTEIN PHD FINGER PROTEIN 24 calmodulin-related#PC00061 HUMAN|HGNC=29890|UniProtKB=Q86UT6 Q86UT6 NLRX1 PTHR24106:SF152 NACHT, LRR AND CARD DOMAINS-CONTAINING NLR FAMILY MEMBER X1 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;negative regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043124;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;negative regulation of response to stimulus#GO:0048585;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=1188|UniProtKB=P56378 P56378 ATP5MPL PTHR15233:SF1 MITOCHONDRIAL PROTEOLIPID ATP SYNTHASE SUBUNIT ATP5MPL, MITOCHONDRIAL HUMAN|HGNC=26074|UniProtKB=Q9NWS1 Q9NWS1 PARPBP PTHR32121:SF0 PCNA-INTERACTING PARTNER PCNA-INTERACTING PARTNER DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of response to DNA damage stimulus#GO:2001021;negative regulation of cellular metabolic process#GO:0031324;regulation of double-strand break repair#GO:2000779;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;negative regulation of DNA repair#GO:0045738;regulation of DNA repair#GO:0006282;nucleobase-containing compound metabolic process#GO:0006139;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;negative regulation of DNA recombination#GO:0045910;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of double-strand break repair#GO:2000780;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of double-strand break repair via homologous recombination#GO:2000042;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;chromatin#GO:0000785;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=786|UniProtKB=P18848 P18848 ATF4 PTHR13044:SF2 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-4 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 Apoptosis signaling pathway#P00006>ATF#P00302 HUMAN|HGNC=16709|UniProtKB=Q16602 Q16602 CALCRL PTHR45620:SF21 PDF RECEPTOR-LIKE PROTEIN-RELATED CALCITONIN GENE-RELATED PEPTIDE TYPE 1 RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=19697|UniProtKB=Q8TDN1 Q8TDN1 KCNG4 PTHR11537:SF167 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY G MEMBER 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=29110|UniProtKB=Q2KHM9 Q2KHM9 KIAA0753 PTHR15732:SF4 UNCHARACTERIZED PROTEIN MOONRAKER HUMAN|HGNC=13886|UniProtKB=Q9H222 Q9H222 ABCG5 PTHR48041:SF113 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 5 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=7163|UniProtKB=Q9ULZ9 Q9ULZ9 MMP17 PTHR10201:SF21 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-17 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141 HUMAN|HGNC=11108|UniProtKB=Q6STE5 Q6STE5 SMARCD3 PTHR13844:SF5 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 3 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;protein-containing complex disassembly#GO:0032984;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=29666|UniProtKB=Q96DP5 Q96DP5 MTFMT PTHR11138:SF5 METHIONYL-TRNA FORMYLTRANSFERASE METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA processing factor#PC00147 HUMAN|HGNC=7548|UniProtKB=P10244 P10244 MYBL2 PTHR45614:SF30 MYB PROTEIN-RELATED MYB-RELATED PROTEIN B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;mitotic nuclear division#GO:0140014;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=35428|UniProtKB=P56277 P56277 CMC4 PTHR15590:SF0 CX9C MOTIF-CONTAINING PROTEIN 4 CX9C MOTIF-CONTAINING PROTEIN 4 HUMAN|HGNC=32153|UniProtKB=A6NM43 A6NM43 CCT8L1P PTHR11353:SF100 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT THETA-LIKE 1-RELATED protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;chaperone complex#GO:0101031;cellular anatomical entity#GO:0110165;chaperonin-containing T-complex#GO:0005832;intracellular#GO:0005622 chaperonin#PC00073 HUMAN|HGNC=25481|UniProtKB=O75648 O75648 TRMU PTHR11933:SF5 TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA methyltransferase#PC00033 HUMAN|HGNC=7183|UniProtKB=P41218 P41218 MNDA PTHR12200:SF27 INTERFERON-INDUCIBLE PROTEIN AIM2 FAMILY MEMBER MYELOID CELL NUCLEAR DIFFERENTIATION ANTIGEN heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;activation of immune response#GO:0002253;response to cytokine#GO:0034097;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;positive regulation of metabolic process#GO:0009893;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;defense response to other organism#GO:0098542;response to chemical#GO:0042221;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of defense response#GO:0031347;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=16627|UniProtKB=O96017 O96017 CHEK2 PTHR44167:SF9 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED SERINE/THREONINE-PROTEIN KINASE CHK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;nuclear division#GO:0000280;cell cycle process#GO:0022402;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;cell cycle checkpoint#GO:0000075;signal transduction in response to DNA damage#GO:0042770;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle#GO:0045786;mitotic DNA damage checkpoint#GO:0044773;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;mitotic DNA integrity checkpoint#GO:0044774;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>Chk2#P01484 HUMAN|HGNC=3023|UniProtKB=P14416 P14416 DRD2 PTHR24248:SF87 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(2) DOPAMINE RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 presynapse#GO:0098793;synapse#GO:0045202;cell junction#GO:0030054;integral component of synaptic membrane#GO:0099699;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;intrinsic component of membrane#GO:0031224;intrinsic component of synaptic membrane#GO:0099240;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Nicotine pharmacodynamics pathway#P06587>DRD2/ DRD3/ DRD4#P06603;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965;Gonadotropin-releasing hormone receptor pathway#P06664>DRD2#P06758 HUMAN|HGNC=30183|UniProtKB=Q9BYD5 Q9BYD5 CNFN PTHR15907:SF26 DUF614 FAMILY PROTEIN-RELATED CORNIFELIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=1551|UniProtKB=P83916 P83916 CBX1 PTHR22812:SF150 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 1 HUMAN|HGNC=26223|UniProtKB=Q96QE5 Q96QE5 TEFM PTHR21053:SF2 UNCHARACTERIZED TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL HUMAN|HGNC=10467|UniProtKB=Q16799 Q16799 RTN1 PTHR45799:SF5 RETICULON-LIKE PROTEIN RETICULON-1 HUMAN|HGNC=5225|UniProtKB=Q03933 Q03933 HSF2 PTHR10015:SF185 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 2 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=11441|UniProtKB=O43752 O43752 STX6 PTHR19957:SF104 SYNTAXIN SYNTAXIN-6 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;vesicle organization#GO:0016050;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;cytosolic transport#GO:0016482;protein localization#GO:0008104;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;SNARE complex#GO:0031201;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;transport vesicle membrane#GO:0030658;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 SNARE protein#PC00034 Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074 HUMAN|HGNC=17935|UniProtKB=Q9UJ71 Q9UJ71 CD207 PTHR22802:SF14 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER K membrane traffic protein#PC00150 HUMAN|HGNC=10484|UniProtKB=Q92736 Q92736 RYR2 PTHR13715:SF75 RYANODINE RECEPTOR AND IP3 RECEPTOR RYANODINE RECEPTOR 2 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;metal ion binding#GO:0046872;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;cation binding#GO:0043169;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;calcium ion binding#GO:0005509;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;sequestering of calcium ion#GO:0051208;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;negative regulation of cellular process#GO:0048523;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;release of sequestered calcium ion into cytosol#GO:0051209;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;regulation of cellular localization#GO:0060341;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065;negative regulation of sequestering of calcium ion#GO:0051283 bounding membrane of organelle#GO:0098588;supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;vacuole#GO:0005773;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;non-membrane-bounded organelle#GO:0043228;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;sarcomere#GO:0030017;transmembrane transporter complex#GO:1902495;cytoplasmic vesicle membrane#GO:0030659;myofibril#GO:0030016;membrane protein complex#GO:0098796;sarcoplasmic reticulum#GO:0016529;intracellular vesicle#GO:0097708;Z disc#GO:0030018;sarcoplasm#GO:0016528;sarcoplasmic reticulum membrane#GO:0033017;ion channel complex#GO:0034702;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;contractile fiber#GO:0043292;cation channel complex#GO:0034703;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;I band#GO:0031674;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;CCKR signaling map#P06959>RYR1/2/3#P07088;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441 HUMAN|HGNC=975|UniProtKB=O75934 O75934 BCAS2 PTHR13296:SF4 BCAS2 PROTEIN PRE-MRNA-SPLICING FACTOR SPF27 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=782|UniProtKB=O95260 O95260 ATE1 PTHR21367:SF1 ARGININE-TRNA-PROTEIN TRANSFERASE 1 ARGINYL-TRNA--PROTEIN TRANSFERASE 1 translational protein#PC00263 HUMAN|HGNC=12963|UniProtKB=Q15697 Q15697 ZNF174 PTHR23226:SF175 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 174 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9765|UniProtKB=Q969Q5 Q969Q5 RAB24 PTHR24073:SF471 DRAB5-RELATED RAS-RELATED PROTEIN RAB-24 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;autophagosome#GO:0005776;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=27254|UniProtKB=Q3MIR4 Q3MIR4 TMEM30B PTHR10926:SF19 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50B organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=29060|UniProtKB=Q658N2 Q658N2 WSCD1 PTHR45964:SF2 WSCD FAMILY MEMBER CG9164 WSC DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=12506|UniProtKB=Q9NPG3 Q9NPG3 UBN1 PTHR21669:SF12 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS UBINUCLEIN-1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=33116|UniProtKB=Q1MX18 Q1MX18 INSC PTHR21386:SF0 INSCUTEABLE PROTEIN INSCUTEABLE HOMOLOG cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 establishment or maintenance of cell polarity#GO:0007163;cell division#GO:0051301;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;nuclear division#GO:0000280;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of cell division#GO:0051302;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle orientation#GO:0000132;establishment of mitotic spindle localization#GO:0040001;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285 cytoplasm#GO:0005737;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular#GO:0005622;apical part of cell#GO:0045177 HUMAN|HGNC=16931|UniProtKB=Q9Y4L1 Q9Y4L1 HYOU1 PTHR45639:SF3 HSC70CB, ISOFORM G-RELATED HYPOXIA UP-REGULATED PROTEIN 1 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to hypoxia#GO:0001666;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;negative regulation of programmed cell death#GO:0043069;response to unfolded protein#GO:0006986;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;cell death#GO:0008219;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;response to oxygen levels#GO:0070482;regulation of programmed cell death#GO:0043067;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;response to decreased oxygen levels#GO:0036293;regulation of response to stress#GO:0080134;programmed cell death#GO:0012501;cellular response to hypoxia#GO:0071456;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cellular response to topologically incorrect protein#GO:0035967;regulation of response to stimulus#GO:0048583;intrinsic apoptotic signaling pathway#GO:0097193;response to stimulus#GO:0050896;negative regulation of cell death#GO:0060548;apoptotic signaling pathway#GO:0097190;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;regulation of cell death#GO:0010941;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of intrinsic apoptotic signaling pathway#GO:2001242;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=23085|UniProtKB=O14559 O14559 ARHGAP33 PTHR15729:SF11 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 33 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 GTPase-activating protein#PC00257 HUMAN|HGNC=6718|UniProtKB=P36941 P36941 LTBR PTHR47607:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 3 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 3 transmembrane signal receptor#PC00197 HUMAN|HGNC=22213|UniProtKB=Q9ULD5 Q9ULD5 ZNF777 PTHR24377:SF927 IP01015P-RELATED ZINC FINGER PROTEIN 777 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=952|UniProtKB=Q99728 Q99728 BARD1 PTHR24171:SF8 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED HUMAN|HGNC=1608|UniProtKB=P32248 P32248 CCR7 PTHR10489:SF635 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 7 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;peptide binding#GO:0042277;cytokine binding#GO:0019955;amide binding#GO:0033218;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;chemokine binding#GO:0019956;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=7226|UniProtKB=O95297 O95297 MPZL1 PTHR13869:SF19 MYELIN P0 RELATED MYELIN PROTEIN ZERO-LIKE PROTEIN 1 myelin protein#PC00161 HUMAN|HGNC=24104|UniProtKB=Q96HD9 Q96HD9 ACY3 PTHR15162:SF5 ASPARTOACYLASE N-ACYL-AROMATIC-L-AMINO ACID AMIDOHYDROLASE (CARBOXYLATE-FORMING) hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=29254|UniProtKB=Q9P2J8 Q9P2J8 ZNF624 PTHR24377:SF823 IP01015P-RELATED ZINC FINGER PROTEIN 624 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25461|UniProtKB=Q9BZE2 Q9BZE2 PUS3 PTHR11142:SF5 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE(38/39) SYNTHASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 lyase#PC00144 HUMAN|HGNC=1623|UniProtKB=P50990 P50990 CCT8 PTHR11353:SF78 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT THETA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;chaperone complex#GO:0101031;cellular anatomical entity#GO:0110165;chaperonin-containing T-complex#GO:0005832;intracellular#GO:0005622 chaperonin#PC00073 HUMAN|HGNC=25037|UniProtKB=Q5TBK1 Q5TBK1 N4BP2L1 PTHR13308:SF5 UNCHARACTERIZED NEDD4-BINDING PROTEIN 2-LIKE 1 HUMAN|HGNC=6241|UniProtKB=Q9UJ90 Q9UJ90 KCNE5 PTHR15282:SF7 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E REGULATORY BETA SUBUNIT 5 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;protein binding#GO:0005515;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 blood circulation#GO:0008015;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of metal ion transport#GO:0010959;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;action potential#GO:0001508;regulation of localization#GO:0032879;regulation of system process#GO:0044057;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;actin-mediated cell contraction#GO:0070252;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;actin filament-based process#GO:0030029;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;monovalent inorganic cation transport#GO:0015672;regulation of multicellular organismal process#GO:0051239;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of heart contraction#GO:0008016;ion transport#GO:0006811;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;regulation of membrane potential#GO:0042391;negative regulation of transport#GO:0051051;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;export from cell#GO:0140352;heart process#GO:0003015;muscle contraction#GO:0006936;negative regulation of molecular function#GO:0044092 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=13342|UniProtKB=Q9NZS2 Q9NZS2 KLRF1 PTHR46746:SF3 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY F MEMBER 2 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY F MEMBER 1 transmembrane signal receptor#PC00197 HUMAN|HGNC=2470|UniProtKB=Q16527 Q16527 CSRP2 PTHR24215:SF3 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488 sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=24342|UniProtKB=O43303 O43303 CCP110 PTHR13594:SF1 CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA HUMAN|HGNC=2750|UniProtKB=Q08211 Q08211 DHX9 PTHR18934:SF119 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA helicase#PC00032 HUMAN|HGNC=19216|UniProtKB=Q99954 Q99954 SMR3A PTHR14179:SF11 SMR1-RELATED SUBMAXILLARY GLAND ANDROGEN-REGULATED PROTEIN 3A peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase inhibitor activity#GO:0004866;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;system process#GO:0003008;biological regulation#GO:0065007;sensory perception of pain#GO:0019233;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;regulation of system process#GO:0044057 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=11395|UniProtKB=Q9UEE5 Q9UEE5 STK17A PTHR24342:SF6 SERINE/THREONINE-PROTEIN KINASE 17 SERINE/THREONINE-PROTEIN KINASE 17A transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;intracellular signal transduction#GO:0035556;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=10972|UniProtKB=Q8TCC7 Q8TCC7 SLC22A8 PTHR24064:SF439 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 8 secondary carrier transporter#PC00258 HUMAN|HGNC=16299|UniProtKB=O15204 O15204 ADAMDEC1 PTHR11905:SF125 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM DEC1 hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 extracellular matrix#GO:0031012;cell periphery#GO:0071944;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=7715|UniProtKB=O00217 O00217 NDUFS8 PTHR10849:SF20 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 8, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 respirasome#GO:0070469;plasma membrane respiratory chain complex I#GO:0045272;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;oxidoreductase complex#GO:1990204;respiratory chain complex I#GO:0045271;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;NADH dehydrogenase complex#GO:0030964;plasma membrane#GO:0005886 oxidoreductase#PC00176 HUMAN|HGNC=26045|UniProtKB=Q9BUN1 Q9BUN1 MENT PTHR16240:SF2 PROTEIN MENT PROTEIN MENT HUMAN|HGNC=25842|UniProtKB=Q6UWX4 Q6UWX4 HHIPL2 PTHR19328:SF54 HEDGEHOG-INTERACTING PROTEIN HHIP-LIKE PROTEIN 2 protein-binding activity modulator#PC00095 HUMAN|HGNC=37284|UniProtKB=C9J069 C9J069 AJM1 PTHR21517:SF3 UNCHARACTERIZED APICAL JUNCTION COMPONENT 1 HOMOLOG HUMAN|HGNC=32350|UniProtKB=A0PJX8 A0PJX8 TMEM82 PTHR35257:SF1 TRANSMEMBRANE PROTEIN 82 TRANSMEMBRANE PROTEIN 82 HUMAN|HGNC=7761|UniProtKB=O76050 O76050 NEURL1 PTHR12429:SF13 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL1 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;developmental process#GO:0032502;multicellular organism development#GO:0007275;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;nervous system development#GO:0007399;cellular process#GO:0009987;negative regulation of Notch signaling pathway#GO:0045746;regulation of Notch signaling pathway#GO:0008593;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;Notch signaling pathway#GO:0007219 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;neuron to neuron synapse#GO:0098984;asymmetric synapse#GO:0032279;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 Notch signaling pathway#P00045>Neuralized#P01117 HUMAN|HGNC=19046|UniProtKB=Q9H2Y9 Q9H2Y9 SLCO5A1 PTHR11388:SF142 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 5A1 secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=25450|UniProtKB=Q9P2F5 Q9P2F5 STOX2 PTHR22437:SF2 WINGED HELIX DOMAIN-CONTAINING PROTEIN STORKHEAD-BOX PROTEIN 2 HUMAN|HGNC=7870|UniProtKB=O94818 O94818 NOL4 PTHR12449:SF17 DEATH DOMAIN-CONTAINING PROTEIN NUCLEOLAR PROTEIN 4 HUMAN|HGNC=4402|UniProtKB=P50151 P50151 GNG10 PTHR13809:SF6 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-10 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 HUMAN|HGNC=34499|UniProtKB=P0DMW4 P0DMW4 SMIM10L2A PTHR34446:SF3 SMALL INTEGRAL MEMBRANE PROTEIN 10 SMALL INTEGRAL MEMBRANE PROTEIN 10-LIKE PROTEIN 2A-RELATED HUMAN|HGNC=29581|UniProtKB=Q8WW18 Q8WW18 C17orf50 PTHR37878:SF1 HYPOTHETICAL PROTEIN LOC689039 DUF4637 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=22212|UniProtKB=Q9ULE3 Q9ULE3 DENND2A PTHR15288:SF3 SUPPRESSION OF TUMORIGENICITY 5 ST5 DENN DOMAIN-CONTAINING PROTEIN 2A Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14490|UniProtKB=Q9P0J6 Q9P0J6 MRPL36 PTHR46909:SF3 39S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=24861|UniProtKB=Q9BUM1 Q9BUM1 G6PC3 PTHR12591:SF2 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;glucose 6-phosphate metabolic process#GO:0051156;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 HUMAN|HGNC=20986|UniProtKB=Q8NB12 Q8NB12 SMYD1 PTHR12197:SF184 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD HISTONE-LYSINE N-METHYLTRANSFERASE SMYD1 N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone methylation#GO:0016571;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;histone lysine methylation#GO:0034968;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=33802|UniProtKB=Q8NA77 Q8NA77 TEX19 PTHR31387:SF0 TESTIS-EXPRESSED PROTEIN 19 TESTIS-EXPRESSED PROTEIN 19 male gamete generation#GO:0048232;reproductive system development#GO:0061458;negative regulation of biological process#GO:0048519;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;sex differentiation#GO:0007548;male gonad development#GO:0008584;cellular process#GO:0009987;multi-organism process#GO:0051704;reproductive structure development#GO:0048608;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;system development#GO:0048731;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;negative regulation of cellular process#GO:0048523;multicellular organismal reproductive process#GO:0048609;transposition#GO:0032196;male sex differentiation#GO:0046661 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=361|UniProtKB=P00568 P00568 AK1 PTHR23359:SF59 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;adenylate kinase activity#GO:0004017;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleoside diphosphate phosphorylation#GO:0006165;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 HUMAN|HGNC=1102|UniProtKB=O95696 O95696 BRD1 PTHR13793:SF17 PHD FINGER PROTEINS BROMODOMAIN-CONTAINING PROTEIN 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein binding#GO:0005515;histone binding#GO:0042393;N-acyltransferase activity#GO:0016410 histone H3 acetylation#GO:0043966;peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 zinc finger transcription factor#PC00244 HUMAN|HGNC=1578|UniProtKB=P20248 P20248 CCNA2 PTHR10177:SF444 CYCLINS CYCLIN-A2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 HUMAN|HGNC=29506|UniProtKB=Q9C0H9 Q9C0H9 SRCIN1 PTHR22741:SF5 P140CAP/SNIP-RELATED SRC KINASE SIGNALING INHIBITOR 1 HUMAN|HGNC=14896|UniProtKB=Q9H254 Q9H254 SPTBN4 PTHR11915:SF232 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 4 Integrin signalling pathway#P00034>alpha actinin#P00928 HUMAN|HGNC=18748|UniProtKB=Q8WYK1 Q8WYK1 CNTNAP5 PTHR15036:SF46 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 5 HUMAN|HGNC=30657|UniProtKB=Q9BRV3 Q9BRV3 SLC50A1 PTHR10791:SF30 RAG1-ACTIVATING PROTEIN 1 SUGAR TRANSPORTER SWEET1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=7161|UniProtKB=P51511 P51511 MMP15 PTHR10201:SF25 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-15 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=9762|UniProtKB=P51153 P51153 RAB13 PTHR47980:SF42 LD44762P RAS-RELATED PROTEIN RAB-13 cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;protein secretion#GO:0009306;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;response to organonitrogen compound#GO:0010243;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;vesicle fusion#GO:0006906;macromolecule localization#GO:0033036;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;cellular protein localization#GO:0034613;transport#GO:0006810;peptide secretion#GO:0002790;cellular response to nitrogen compound#GO:1901699;amide transport#GO:0042886;organic substance transport#GO:0071702;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;regulation of transport#GO:0051049;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;vesicle organization#GO:0016050;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;response to organic substance#GO:0010033;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;protein localization to membrane#GO:0072657;cellular response to peptide#GO:1901653;Golgi vesicle transport#GO:0048193;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;localization#GO:0051179;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;response to hormone#GO:0009725;membrane fusion#GO:0061025;response to chemical#GO:0042221;organelle organization#GO:0006996;biological regulation#GO:0065007 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;trans-Golgi network transport vesicle#GO:0030140;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=5624|UniProtKB=A0A0B4J1X5 A0A0B4J1X5 IGHV3-74 PTHR23266:SF219 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-74 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=24550|UniProtKB=Q9H8H3 Q9H8H3 METTL7A PTHR42912:SF21 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 7A methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155 HUMAN|HGNC=25772|UniProtKB=Q6P1M9 Q6P1M9 ARMCX5 PTHR47081:SF2 FAMILY NOT NAMED ARMADILLO REPEAT-CONTAINING X-LINKED PROTEIN 5 HUMAN|HGNC=21695|UniProtKB=Q9Y6U3 Q9Y6U3 SCIN PTHR11977:SF78 VILLIN ADSEVERIN non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 HUMAN|HGNC=18435|UniProtKB=Q8WVB6 Q8WVB6 CHTF18 PTHR23389:SF3 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 CHROMOSOME TRANSMISSION FIDELITY PROTEIN 18 HOMOLOG nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=11337|UniProtKB=Q99909 Q99909 SSX3 PTHR14112:SF19 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=31797|UniProtKB=P0C7V6 P0C7V6 SUPT20HL2 PTHR13526:SF24 TRANSCRIPTION FACTOR SPT20 HOMOLOG TRANSCRIPTION FACTOR SPT20 HOMOLOG-LIKE 2-RELATED cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=16874|UniProtKB=Q7L1I2 Q7L1I2 SV2B PTHR23511:SF2 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2B bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=2713|UniProtKB=O75935 O75935 DCTN3 PTHR28360:SF1 DYNACTIN SUBUNIT 3 DYNACTIN SUBUNIT 3 cellular component organization or biogenesis#GO:0071840;cell division#GO:0051301;membrane fission#GO:0090148;membrane organization#GO:0061024;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156 HUMAN|HGNC=2523|UniProtKB=Q99895 Q99895 CTRC PTHR24250:SF35 CHYMOTRYPSIN-RELATED CHYMOTRYPSIN-C serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203 HUMAN|HGNC=19715|UniProtKB=Q9HAW4 Q9HAW4 CLSPN PTHR14396:SF10 CLASPIN CLASPIN protein-containing complex binding#GO:0044877;binding#GO:0005488 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;positive regulation of macromolecule metabolic process#GO:0010604;mitotic DNA integrity checkpoint#GO:0044774;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;cell cycle G2/M phase transition#GO:0044839;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;regulation of phosphate metabolic process#GO:0019220;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;protein modification process#GO:0036211;negative regulation of cell cycle process#GO:0010948;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;mitotic DNA replication checkpoint#GO:0033314;phosphate-containing compound metabolic process#GO:0006796;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;G2 DNA damage checkpoint#GO:0031572;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle G2/M phase transition#GO:1902750;positive regulation of catalytic activity#GO:0043085;negative regulation of cell cycle phase transition#GO:1901988;organonitrogen compound metabolic process#GO:1901564;mitotic DNA damage checkpoint#GO:0044773;protein phosphorylation#GO:0006468;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;DNA replication checkpoint#GO:0000076;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;mitotic G2 DNA damage checkpoint#GO:0007095;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of mitotic cell cycle#GO:0007346 HUMAN|HGNC=32388|UniProtKB=A6NDD5 A6NDD5 SYNDIG1L PTHR14768:SF4 UPF0338 PROTEIN SYNAPSE DIFFERENTIATION-INDUCING GENE PROTEIN 1-LIKE HUMAN|HGNC=26035|UniProtKB=Q6P1K1 Q6P1K1 SLC48A1 PTHR31525:SF1 HEME TRANSPORTER HRG1 HEME TRANSPORTER HRG1 tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;cation transport#GO:0006812 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=30565|UniProtKB=O14562 O14562 UBFD1 PTHR16470:SF0 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515 HUMAN|HGNC=12127|UniProtKB=P04437 P04437 TRAV29DV5 PTHR19343:SF21 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 29/DELTA VARIABLE 5 HUMAN|HGNC=11514|UniProtKB=O43581 O43581 SYT7 PTHR10024:SF366 SYNAPTOTAGMIN SYNAPTOTAGMIN-7 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cation transport#GO:0006812;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;vesicle-mediated transport#GO:0016192;response to metal ion#GO:0010038;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;membrane fusion#GO:0061025;exocytosis#GO:0006887;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;export from cell#GO:0140352 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cell projection#GO:0042995;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 HUMAN|HGNC=32689|UniProtKB=P0C7P3 P0C7P3 SLFN14 PTHR12155:SF30 SCHLAFEN PROTEIN SLFN14 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 HUMAN|HGNC=17321|UniProtKB=Q8TDD2 Q8TDD2 SP7 PTHR23235:SF19 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=5923|UniProtKB=A0A0G2JS06 A0A0G2JS06 IGLV5-39 PTHR23267:SF325 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 5-37-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=19006|UniProtKB=Q86Z02 Q86Z02 HIPK1 PTHR24058:SF43 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 1 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;signal transduction by p53 class mediator#GO:0072331;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;cell death#GO:0008219;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;cellular response to stimulus#GO:0051716;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;peptidyl-threonine phosphorylation#GO:0018107;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;PML body#GO:0016605 HUMAN|HGNC=3026|UniProtKB=P21918 P21918 DRD5 PTHR24248:SF136 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(1B) DOPAMINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948 HUMAN|HGNC=19988|UniProtKB=Q9H1A4 Q9H1A4 ANAPC1 PTHR12827:SF3 MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER ANAPHASE-PROMOTING COMPLEX SUBUNIT 1 molecular adaptor activity#GO:0060090;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity, acting on a protein#GO:0140096 regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;protein catabolic process#GO:0030163;regulation of cellular component organization#GO:0051128;chromosome segregation#GO:0007059;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of mitotic sister chromatid segregation#GO:0033047;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;protein K11-linked ubiquitination#GO:0070979;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;mitotic cell cycle process#GO:1903047;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;metaphase/anaphase transition of cell cycle#GO:0044784;cellular protein catabolic process#GO:0044257;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of mitotic cell cycle#GO:0007346 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9873|UniProtKB=O95294 O95294 RASAL1 PTHR10194:SF3 RAS GTPASE-ACTIVATING PROTEINS RASGAP-ACTIVATING-LIKE PROTEIN 1 GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646 HUMAN|Ensembl=ENSG00000285071|UniProtKB=A0A126GWB0 A0A126GWB0 OR2A2 PTHR26453:SF82 OLFACTORY RECEPTOR OLFACTORY RECEPTOR-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=12887|UniProtKB=Q9UII5 Q9UII5 ZNF107 PTHR24376:SF79 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 107 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26891|UniProtKB=Q6P531 Q6P531 GGT6 PTHR47278:SF1 GLUTATHIONE HYDROLASE 6 GLUTATHIONE HYDROLASE 6 membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 hydrolase#PC00121 HUMAN|HGNC=13208|UniProtKB=Q9H9E1 Q9H9E1 ANKRA2 PTHR24124:SF3 ANKYRIN REPEAT FAMILY A ANKYRIN REPEAT FAMILY A PROTEIN 2 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=9044|UniProtKB=Q9HBJ0 Q9HBJ0 PLAC1 PTHR14380:SF2 PLACENTA-SPECIFIC PROTEIN 1 PLACENTA-SPECIFIC PROTEIN 1 HUMAN|HGNC=7221|UniProtKB=Q13368 Q13368 MPP3 PTHR23122:SF33 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 3 scaffold/adaptor protein#PC00226 HUMAN|HGNC=108|UniProtKB=P22303 P22303 ACHE PTHR11559:SF411 CARBOXYLESTERASE ACETYLCHOLINESTERASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 HUMAN|HGNC=2752|UniProtKB=O75925 O75925 PIAS1 PTHR10782:SF11 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;RNA polymerase II transcription factor binding#GO:0001085;molecular function regulator#GO:0098772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;transcription factor binding#GO:0008134 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 JAK/STAT signaling pathway#P00038>PIAS#P01031;Interferon-gamma signaling pathway#P00035>PIAS#P00958 HUMAN|HGNC=2062|UniProtKB=O00299 O00299 CLIC1 PTHR43920:SF2 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ion channel#PC00133 HUMAN|HGNC=31988|UniProtKB=Q5VWK0 Q5VWK0 NBPF6 PTHR14199:SF29 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 4-RELATED HUMAN|HGNC=22981|UniProtKB=Q5PT55 Q5PT55 SLC10A5 PTHR10361:SF29 SODIUM-BILE ACID COTRANSPORTER SODIUM/BILE ACID COTRANSPORTER 5 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068 HUMAN|HGNC=8693|UniProtKB=Q9UN66 Q9UN66 PCDHB8 PTHR24028:SF150 CADHERIN-87A PROTOCADHERIN BETA-8 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=4395|UniProtKB=P19086 P19086 GNAZ PTHR10218:SF65 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(Z) SUBUNIT ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 Dopamine receptor mediated signaling pathway#P05912>GNAZ#P05964 HUMAN|HGNC=5799|UniProtKB=P01615 P01615 IGKV2D-28 PTHR23267:SF453 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-28-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=163|UniProtKB=P12814 P12814 ACTN1 PTHR11915:SF434 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-1 Integrin signalling pathway#P00034>alpha actinin#P00928 HUMAN|HGNC=14130|UniProtKB=Q9BRR9 Q9BRR9 ARHGAP9 PTHR23176:SF103 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 9 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|Gene=YB057_HUMAN|UniProtKB=A8MUA0 A8MUA0 - PTHR11639:SF135 S100 CALCIUM-BINDING PROTEIN UPF0607 PROTEIN ENSP00000381514-RELATED protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=12570|UniProtKB=Q86WB7 Q86WB7 UNC93A PTHR19444:SF13 UNC-93 RELATED PROTEIN UNC-93 HOMOLOG A membrane-bound signaling molecule#PC00152 HUMAN|HGNC=4545|UniProtKB=P43250 P43250 GRK6 PTHR24355:SF15 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 6 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK6#P05939;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GPRK#P00840;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 HUMAN|HGNC=37166|UniProtKB=P0CJ76 P0CJ76 MTRNR2L9 PTHR33895:SF18 HUMANIN-LIKE 4 HUMANIN-LIKE 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=13476|UniProtKB=Q9H313 Q9H313 TTYH1 PTHR12424:SF5 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=18620|UniProtKB=Q9H9E3 Q9H9E3 COG4 PTHR24016:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 membrane traffic protein#PC00150 HUMAN|HGNC=13146|UniProtKB=Q96N20 Q96N20 ZNF75A PTHR24381:SF268 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 75A DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=34433|UniProtKB=Q30KP8 Q30KP8 DEFB136 PTHR39413:SF1 BETA-DEFENSIN 136 BETA-DEFENSIN 136 antimicrobial response protein#PC00051 HUMAN|HGNC=10526|UniProtKB=Q9Y467 Q9Y467 SALL2 PTHR23233:SF15 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26517|UniProtKB=Q96MD2 Q96MD2 C12orf66 PTHR31581:SF1 KICSTOR COMPLEX PROTEIN C12ORF66 KICSTOR COMPLEX PROTEIN C12ORF66 cellular localization#GO:0051641;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;regulation of signal transduction#GO:0009966;protein localization to organelle#GO:0033365;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;TORC1 signaling#GO:0038202;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;protein localization to vacuole#GO:0072665;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;protein localization#GO:0008104;localization#GO:0051179;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554 protein-containing complex#GO:0032991 HUMAN|HGNC=24435|UniProtKB=Q9NRR1 Q9NRR1 CYTL1 PTHR15974:SF0 CYTOKINE-LIKE PROTEIN 1 CYTOKINE-LIKE PROTEIN 1 cytokine#PC00083 HUMAN|HGNC=16258|UniProtKB=Q6GMV2 Q6GMV2 SMYD5 PTHR46402:SF2 SET AND MYND DOMAIN-CONTAINING PROTEIN 5 SET AND MYND DOMAIN-CONTAINING PROTEIN 5 HUMAN|HGNC=15235|UniProtKB=Q8NGF1 Q8NGF1 OR52R1 PTHR26450:SF156 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52R1 transmembrane signal receptor#PC00197 HUMAN|HGNC=19218|UniProtKB=Q86YW0 Q86YW0 PLCZ1 PTHR10336:SF29 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ZETA-1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;fertilization#GO:0009566;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;positive regulation of cytosolic calcium ion concentration#GO:0007204;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;reproductive process#GO:0022414;cellular divalent inorganic cation homeostasis#GO:0072503;phosphatidylinositol-mediated signaling#GO:0048015;intracellular signal transduction#GO:0035556;multi-organism reproductive process#GO:0044703;signaling#GO:0023052;cellular cation homeostasis#GO:0030003;cellular response to stimulus#GO:0051716;single fertilization#GO:0007338;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;multi-organism process#GO:0051704;cellular ion homeostasis#GO:0006873;cell activation#GO:0001775;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;reproduction#GO:0000003;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;metal ion homeostasis#GO:0055065 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 HUMAN|HGNC=26513|UniProtKB=Q96MF7 Q96MF7 NSMCE2 PTHR21330:SF1 UNCHARACTERIZED E3 SUMO-PROTEIN LIGASE NSE2 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;peptidyl-lysine modification#GO:0018205;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11242|UniProtKB=Q01892 Q01892 SPIB PTHR11849:SF174 ETS TRANSCRIPTION FACTOR SPI-B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=26183|UniProtKB=Q6DN14 Q6DN14 MCTP1 PTHR45911:SF3 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;regulation of cellular process#GO:0050794;regulation of neurotransmitter levels#GO:0001505;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;export from cell#GO:0140352 bounding membrane of organelle#GO:0098588;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;intrinsic component of membrane#GO:0031224;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=32256|UniProtKB=A6NJQ4 A6NJQ4 FAM90A8P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=20364|UniProtKB=A1L390 A1L390 PLEKHG3 PTHR45924:SF4 FI17866P1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 3 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 HUMAN|HGNC=24463|UniProtKB=Q8WUN7 Q8WUN7 UBTD2 PTHR13609:SF20 UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED UBIQUITIN DOMAIN-CONTAINING PROTEIN 2 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=30465|UniProtKB=Q6PCB8 Q6PCB8 EMB PTHR10075:SF4 BASIGIN RELATED EMBIGIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=1424|UniProtKB=P27708 P27708 CAD PTHR11405:SF5 CARBAMOYLTRANSFERASE FAMILY MEMBER CAD PROTEIN oxoacid metabolic process#GO:0043436;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid metabolic process#GO:0006520;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925;Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845 HUMAN|HGNC=4332|UniProtKB=Q9NZM4 Q9NZM4 BICRA PTHR15572:SF1 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 BRD4-INTERACTING CHROMATIN-REMODELING COMPLEX-ASSOCIATED PROTEIN transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=28174|UniProtKB=Q8NBV4 Q8NBV4 PLPP7 PTHR14969:SF17 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE INACTIVE PHOSPHOLIPID PHOSPHATASE 7 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=19425|UniProtKB=Q96P70 Q96P70 IPO9 PTHR10997:SF9 IMPORTIN-7, 8, 11 IMPORTIN-9 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=28826|UniProtKB=Q6UXN9 Q6UXN9 WDR82 PTHR19861:SF0 WD40 REPEAT PROTEIN SWD2 WD REPEAT-CONTAINING PROTEIN 82 N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;chromatin binding#GO:0003682;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;histone methylation#GO:0016571;peptidyl-amino acid modification#GO:0018193;protein alkylation#GO:0008213;protein methylation#GO:0006479;nitrogen compound metabolic process#GO:0006807;histone H3-K4 methylation#GO:0051568;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;histone modification#GO:0016570;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;histone lysine methylation#GO:0034968;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;methylation#GO:0032259;macromolecule methylation#GO:0043414;chromosome organization#GO:0051276;organelle organization#GO:0006996;peptidyl-lysine trimethylation#GO:0018023;chromatin organization#GO:0006325 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 methyltransferase#PC00155 HUMAN|HGNC=8903|UniProtKB=O95336 O95336 PGLS PTHR11054:SF0 6-PHOSPHOGLUCONOLACTONASE 6-PHOSPHOGLUCONOLACTONASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;NADP metabolic process#GO:0006739;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glucose 6-phosphate metabolic process#GO:0051156 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 HUMAN|HGNC=18522|UniProtKB=Q5VV16 Q5VV16 FOXD4L5 PTHR11829:SF381 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-LIKE 3-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=21675|UniProtKB=Q5CZC0 Q5CZC0 FSIP2 PTHR21856:SF7 FIBROUS SHEATH-INTERACTING PROTEIN 2 FIBROUS SHEATH-INTERACTING PROTEIN 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=20387|UniProtKB=Q9P2X3 Q9P2X3 IMPACT PTHR16301:SF22 IMPACT-RELATED PROTEIN IMPACT protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of translational initiation#GO:0045948;gene expression#GO:0010467;response to extracellular stimulus#GO:0009991;regulation of translational initiation#GO:0006446;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;peptide biosynthetic process#GO:0043043;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;translational elongation#GO:0006414;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;translation#GO:0006412;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;cellular response to starvation#GO:0009267;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of phosphorus metabolic process#GO:0010563;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;response to nutrient levels#GO:0031667;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to nutrient levels#GO:0031669;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;response to starvation#GO:0042594;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;cellular response to external stimulus#GO:0071496;translational initiation#GO:0006413;positive regulation of cellular protein metabolic process#GO:0032270;cellular response to amino acid starvation#GO:0034198;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 ribonucleoprotein complex#GO:1990904;polysome#GO:0005844;protein-containing complex#GO:0032991 HUMAN|HGNC=12192|UniProtKB=A0A087X0K7 A0A087X0K7 TRBV17 PTHR23268:SF93 T-CELL RECEPTOR BETA CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=5716|UniProtKB=P01834 P01834 IGKC PTHR23266:SF79 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN KAPPA CONSTANT protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=8070|UniProtKB=O15381 O15381 NVL PTHR23077:SF156 AAA-FAMILY ATPASE NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;ribosome biogenesis#GO:0042254;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;RNA-dependent DNA biosynthetic process#GO:0006278;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;DNA biosynthetic process#GO:0071897;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10927|UniProtKB=O15403 O15403 SLC16A6 PTHR11360:SF20 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 7 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=15788|UniProtKB=Q96DT0 Q96DT0 LGALS12 PTHR11346:SF111 GALECTIN GALECTIN-12 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;carbohydrate binding#GO:0030246;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 circulatory system development#GO:0072359;multicellular organism development#GO:0007275;developmental process#GO:0032502;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;endothelial cell migration#GO:0043542;localization#GO:0051179;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;cell migration#GO:0016477;locomotion#GO:0040011 extracellular matrix protein#PC00102 HUMAN|HGNC=2528|UniProtKB=P53634 P53634 CTSC PTHR12411:SF840 CYSTEINE PROTEASE FAMILY C1-RELATED DIPEPTIDYL PEPTIDASE 1-RELATED cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=8790|UniProtKB=Q13956 Q13956 PDE6H PTHR12122:SF5 RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT GAMMA regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 bounding membrane of organelle#GO:0098588;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 phosphodiesterase#PC00185 HUMAN|HGNC=2701|UniProtKB=P43146 P43146 DCC PTHR44170:SF8 PROTEIN SIDEKICK NETRIN RECEPTOR DCC Axon guidance mediated by netrin#P00009>DCC/UNC-40#P00360;Axon guidance mediated by Slit/Robo#P00008>DCC#P00352 HUMAN|HGNC=4036|UniProtKB=O15117 O15117 FYB1 PTHR16830:SF13 SH2 CONTAINING ADAPTOR PRAM-1 RELATED FYN-BINDING PROTEIN 1 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular localization#GO:0051641;signal transduction#GO:0007165;activation of immune response#GO:0002253;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;integrin-mediated signaling pathway#GO:0007229;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;signaling#GO:0023052;protein localization to plasma membrane#GO:0072659;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;protein localization to membrane#GO:0072657;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18790|UniProtKB=P42857 P42857 NSG1 PTHR28546:SF3 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 endosomal transport#GO:0016197;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cellular protein-containing complex assembly#GO:0034622;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex subunit organization#GO:0043933 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=15867|UniProtKB=Q9BYJ9 Q9BYJ9 YTHDF1 PTHR12357:SF65 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 1 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of translational initiation#GO:0045948;gene expression#GO:0010467;regulation of translational initiation#GO:0006446;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;translational initiation#GO:0006413;positive regulation of RNA metabolic process#GO:0051254;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=34450|UniProtKB=Q69YU5 Q69YU5 BRAWNIN PTHR28492:SF1 HYPOTHETICAL PROTEIN LOC691921 PROTEIN BRAWNIN HUMAN|HGNC=28492|UniProtKB=Q5HYJ3 Q5HYJ3 FAM76B PTHR46176:SF3 LD21662P PROTEIN FAM76B HUMAN|HGNC=29134|UniProtKB=A2RUS2 A2RUS2 DENND3 PTHR12296:SF28 C-MYC PROMOTER BINDING PROTEIN DENN DOMAIN-CONTAINING PROTEIN 3 Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;regulation of Ras protein signal transduction#GO:0046578;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=12371|UniProtKB=Q8WYR4 Q8WYR4 RSPH1 PTHR43215:SF4 RADIAL SPOKE HEAD 1 HOMOLOG RADIAL SPOKE HEAD 1 HOMOLOG cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=35462|UniProtKB=A6NKU9 A6NKU9 SPDYE3 PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=5287|UniProtKB=P28222 P28222 HTR1B PTHR24247:SF16 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1B cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;negative regulation of biological process#GO:0048519;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;negative regulation of intracellular signal transduction#GO:1902532;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;negative regulation of catalytic activity#GO:0043086;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935;negative regulation of molecular function#GO:0044092 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 HUMAN|HGNC=25366|UniProtKB=Q5T0J7 Q5T0J7 TEX35 PTHR36860:SF1 TESTIS-EXPRESSED PROTEIN 35 TESTIS-EXPRESSED PROTEIN 35 HUMAN|HGNC=29330|UniProtKB=Q9HCE5 Q9HCE5 METTL14 PTHR13107:SF0 N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;macromolecule methylation#GO:0043414;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=23843|UniProtKB=Q96IK5 Q96IK5 GMCL1 PTHR23231:SF19 GERM CELL-LESS PROTEIN GERM CELL-LESS PROTEIN-LIKE 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=2879|UniProtKB=Q8WYJ6 Q8WYJ6 SEPTIN1 PTHR18884:SF6 SEPTIN SEPTIN-1 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 vesicle fusion#GO:0006906;cellular localization#GO:0051641;cell division#GO:0051301;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;cell cycle process#GO:0022402;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;cytoskeleton-dependent cytokinesis#GO:0061640;vesicle organization#GO:0016050;cytokinesis#GO:0000910;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;membrane fission#GO:0090148;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;export from cell#GO:0140352 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell division site#GO:0032153;transport vesicle#GO:0030133;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 HUMAN|HGNC=14055|UniProtKB=Q7Z7H8 Q7Z7H8 MRPL10 PTHR11560:SF12 39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=12660|UniProtKB=Q5SQQ9 Q5SQQ9 VAX1 PTHR24339:SF32 HOMEOBOX PROTEIN EMX-RELATED VENTRAL ANTERIOR HOMEOBOX 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=9452|UniProtKB=Q9UNN8 Q9UNN8 PROCR PTHR15349:SF0 ENDOTHELIAL PROTEIN C RECEPTOR ENDOTHELIAL PROTEIN C RECEPTOR regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;negative regulation of coagulation#GO:0050819;regulation of coagulation#GO:0050818;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;coagulation#GO:0050817 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protein-binding activity modulator#PC00095 Blood coagulation#P00011>EPCR#P00403 HUMAN|HGNC=6879|UniProtKB=Q16659 Q16659 MAPK6 PTHR24055:SF171 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 6 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Integrin signalling pathway#P00034>ERK#P00907;Angiogenesis#P00005>MEK#P00225;VEGF signaling pathway#P00056>MEK#P01402;Interleukin signaling pathway#P00036>ERK#P00965;PDGF signaling pathway#P00047>ERK#P01143;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099 HUMAN|HGNC=33358|UniProtKB=A6NK44 A6NK44 GLOD5 PTHR21366:SF14 GLYOXALASE FAMILY PROTEIN GLYOXALASE DOMAIN-CONTAINING PROTEIN 5 HUMAN|HGNC=10615|UniProtKB=Q92583 Q92583 CCL17 PTHR12015:SF111 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 17 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=12825|UniProtKB=O14980 O14980 XPO1 PTHR11223:SF2 EXPORTIN 1/5 EXPORTIN-1 transporter activity#GO:0005215 cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;ribosome biogenesis#GO:0042254;regulation of protein transport#GO:0051223;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;regulation of protein localization#GO:0032880;establishment of RNA localization#GO:0051236;peptide transport#GO:0015833;ribonucleoprotein complex localization#GO:0071166;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;regulation of establishment of protein localization#GO:0070201;protein-containing complex localization#GO:0031503;regulation of peptide transport#GO:0090087 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=32537|UniProtKB=Q58FF8 Q58FF8 HSP90AB2P PTHR11528:SF78 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-BETA 2-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of biological quality#GO:0065008;response to heat#GO:0009408;protein folding#GO:0006457;cellular response to heat#GO:0034605;biological regulation#GO:0065007;regulation of protein stability#GO:0031647;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;cellular process#GO:0009987;protein stabilization#GO:0050821 cytoplasm#GO:0005737;cell surface#GO:0009986;perinuclear region of cytoplasm#GO:0048471;intracellular#GO:0005622;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Hsp90 family chaperone#PC00028 HUMAN|HGNC=26757|UniProtKB=A6NC98 A6NC98 CCDC88B PTHR18947:SF35 HOOK PROTEINS COILED-COIL DOMAIN-CONTAINING PROTEIN 88B cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 membrane traffic protein#PC00150 HUMAN|HGNC=11562|UniProtKB=Q92844 Q92844 TANK PTHR15249:SF0 TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR Toll receptor signaling pathway#P00054>TANK#P01353 HUMAN|HGNC=10524|UniProtKB=Q9NSC2 Q9NSC2 SALL1 PTHR23233:SF51 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=12021|UniProtKB=O60704 O60704 TPST2 PTHR12788:SF6 PROTEIN-TYROSINE SULFOTRANSFERASE 2 PROTEIN-TYROSINE SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;peptidyl-tyrosine modification#GO:0018212;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=10290|UniProtKB=P15927 P15927 RPA2 PTHR13989:SF43 REPLICATION PROTEIN A-RELATED REPLICATION PROTEIN A 30 KDA SUBUNIT-RELATED DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 pre-replicative complex#GO:0036387;intracellular membrane-bounded organelle#GO:0043231;epsilon DNA polymerase complex#GO:0008622;replisome#GO:0030894;MCM complex#GO:0042555;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;chromosomal region#GO:0098687;replication fork#GO:0005657;membrane-enclosed lumen#GO:0031974;origin recognition complex#GO:0000808;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;DNA replication preinitiation complex#GO:0031261;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;CMG complex#GO:0071162;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;chromosome, telomeric region#GO:0000781;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 DNA replication#P00017>RPA#P00537 HUMAN|HGNC=10585|UniProtKB=P35498 P35498 SCN1A PTHR10037:SF280 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 1 SUBUNIT ALPHA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sodium channel activity#GO:0005272;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;sodium ion transport#GO:0006814;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=30055|UniProtKB=Q12893 Q12893 TMEM115 PTHR13377:SF3 PLACENTAL PROTEIN 6 TRANSMEMBRANE PROTEIN 115 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=25645|UniProtKB=Q8N682 Q8N682 DRAM1 PTHR21324:SF11 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 1 process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;biological regulation#GO:0065007;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;cellular catabolic process#GO:0044248;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14511|UniProtKB=P82663 P82663 MRPS25 PTHR13274:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S25 28S RIBOSOMAL PROTEIN S25, MITOCHONDRIAL ribosomal protein#PC00202 HUMAN|HGNC=25396|UniProtKB=Q5SZK8 Q5SZK8 FREM2 PTHR45739:SF4 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 2 HUMAN|HGNC=30948|UniProtKB=Q52M93 Q52M93 ZNF585B PTHR24376:SF197 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 585A-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4962|UniProtKB=P13747 P13747 HLA-E PTHR16675:SF164 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN E protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;amide binding#GO:0033218;peptide binding#GO:0042277 immune response#GO:0006955;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;T cell mediated immunity#GO:0002456;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=28274|UniProtKB=Q96GL9 Q96GL9 FAM163A PTHR31914:SF2 PROTEIN FAM163A PROTEIN FAM163A HUMAN|HGNC=2770|UniProtKB=P17661 P17661 DES PTHR45652:SF2 GLIAL FIBRILLARY ACIDIC PROTEIN DESMIN HUMAN|HGNC=16792|UniProtKB=Q92540 Q92540 SMG7 PTHR15696:SF5 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 PROTEIN SMG7 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;heterocyclic compound binding#GO:1901363;telomerase RNA binding#GO:0070034 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;telomerase holoenzyme complex#GO:0005697;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=9350|UniProtKB=Q9NQX0 Q9NQX0 PRDM6 PTHR16515:SF22 PR DOMAIN ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM6-RELATED regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26798|UniProtKB=Q8N8R7 Q8N8R7 ARL14EP PTHR46536:SF1 ARL14 EFFECTOR PROTEIN ARL14 EFFECTOR PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=8965|UniProtKB=Q92643 Q92643 PIGK PTHR48067:SF1 GPI-ANCHOR TRANSAMIDASE GPI-ANCHOR TRANSAMIDASE hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 lipid metabolic process#GO:0006629;cellular localization#GO:0051641;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;protein localization to cell surface#GO:0034394;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;cellular macromolecule localization#GO:0070727;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=10701|UniProtKB=Q15436 Q15436 SEC23A PTHR11141:SF7 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23A pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;Golgi vesicle budding#GO:0048194;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=11738|UniProtKB=Q9BXT5 Q9BXT5 TEX15 PTHR22380:SF1 TESTIS-EXPRESSED PROTEIN 15 TESTIS-EXPRESSED PROTEIN 15 HUMAN|HGNC=7644|UniProtKB=P49321 P49321 NASP PTHR15081:SF1 NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED NUCLEAR AUTOANTIGENIC SPERM PROTEIN protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cellular protein-containing complex assembly#GO:0034622;chromatin assembly or disassembly#GO:0006333;histone exchange#GO:0043486;nucleosome organization#GO:0034728;macromolecule localization#GO:0033036;nucleosome assembly#GO:0006334;cellular protein localization#GO:0034613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;chromosome organization#GO:0051276;ATP-dependent chromatin remodeling#GO:0043044;chromatin organization#GO:0006325;protein localization to organelle#GO:0033365;chromatin remodeling#GO:0006338;protein-containing complex subunit organization#GO:0043933;DNA replication-independent nucleosome organization#GO:0034724 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=22030|UniProtKB=Q8N8M0 Q8N8M0 NAT16 PTHR43072:SF19 N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE 16-RELATED transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 acetyltransferase#PC00038 HUMAN|HGNC=23091|UniProtKB=Q8WWX8 Q8WWX8 SLC5A11 PTHR11819:SF171 SOLUTE CARRIER FAMILY 5 SODIUM/MYO-INOSITOL COTRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;monovalent inorganic cation transmembrane transporter activity#GO:0015077;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;ion transmembrane transporter activity#GO:0015075;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=18802|UniProtKB=Q8N5M1 Q8N5M1 ATPAF2 PTHR21013:SF10 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2 chaperone#PC00072 HUMAN|HGNC=18058|UniProtKB=Q96DR4 Q96DR4 STARD4 PTHR47006:SF1 STAR-RELATED LIPID TRANSFER PROTEIN 4 STAR-RELATED LIPID TRANSFER PROTEIN 4 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;cholesterol binding#GO:0015485 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;intracellular sterol transport#GO:0032366;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cholesterol transport#GO:0030301;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;maintenance of location#GO:0051235;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lipid localization#GO:0010876;lipid storage#GO:0019915 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=8861|UniProtKB=P02776 P02776 PF4 PTHR10179:SF43 CXC CHEMOKINE PLATELET FACTOR 4 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=20742|UniProtKB=Q5TGI0 Q5TGI0 FAXC PTHR12289:SF41 METAXIN RELATED FAILED AXON CONNECTIONS HOMOLOG HUMAN|HGNC=6278|UniProtKB=O14649 O14649 KCNK3 PTHR11003:SF138 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 Dopamine receptor mediated signaling pathway#P05912>K+ channel#P05957;5HT4 type receptor mediated signaling pathway#P04376>K+ channel#P04426;Nicotine pharmacodynamics pathway#P06587>KCNK3/9#P06605;5HT2 type receptor mediated signaling pathway#P04374>K+ channel#P04413;Opioid proenkephalin pathway#P05915>K+ channel#P05990;5HT1 type receptor mediated signaling pathway#P04373>K+ channel#P04407;Opioid proopiomelanocortin pathway#P05917>K+ channel#P06009;5HT3 type receptor mediated signaling pathway#P04375>K+ channel#P04425 HUMAN|HGNC=18827|UniProtKB=Q86X67 Q86X67 NUDT13 PTHR11383:SF3 NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 13 NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 13 HUMAN|HGNC=37172|UniProtKB=A6NEV1 A6NEV1 PRR23A PTHR31813:SF4 PROLINE-RICH PROTEIN 23B PROLINE-RICH PROTEIN 23A HUMAN|HGNC=28459|UniProtKB=Q71RG4 Q71RG4 TMUB2 PTHR14557:SF4 PROTEIN C7ORF21 TRANSMEMBRANE AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN 2 cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 HUMAN|HGNC=16914|UniProtKB=O75325 O75325 LRRN2 PTHR24373:SF162 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT NEURONAL PROTEIN 2 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=14262|UniProtKB=Q8WXX7 Q8WXX7 AUTS2 PTHR14429:SF5 FIBROSIN FAMILY MEMBER AUTISM SUSCEPTIBILITY GENE 2 PROTEIN HUMAN|HGNC=19680|UniProtKB=Q8TDU6 Q8TDU6 GPBAR1 PTHR24246:SF31 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR G-PROTEIN COUPLED BILE ACID RECEPTOR 1 G-protein coupled receptor#PC00021 HUMAN|HGNC=10731|UniProtKB=Q9C0C4 Q9C0C4 SEMA4C PTHR11036:SF16 SEMAPHORIN SEMAPHORIN-4C receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;muscle cell differentiation#GO:0042692;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;negative regulation of cellular component organization#GO:0051129;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;negative regulation of locomotion#GO:0040013;neuron projection extension#GO:1990138;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;growth#GO:0040007;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;muscle structure development#GO:0061061;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;developmental growth involved in morphogenesis#GO:0060560;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell motility#GO:2000145;regulation of cell development#GO:0060284;developmental growth#GO:0048589;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=23337|UniProtKB=Q8NC06 Q8NC06 ACBD4 PTHR23310:SF53 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4 transfer/carrier protein#PC00219 HUMAN|HGNC=27548|UniProtKB=Q9NX77 Q9NX77 ERVK13-1 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED viral or transposable element protein#PC00237 HUMAN|HGNC=25801|UniProtKB=Q9H799 Q9H799 CPLANE1 PTHR14492:SF4 JBTS17 CILIOGENESIS AND PLANAR POLARITY EFFECTOR 1 HUMAN|HGNC=15290|UniProtKB=Q6IEU7 Q6IEU7 OR5M10 PTHR48018:SF85 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M10 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=1736|UniProtKB=P60953 P60953 CDC42 PTHR24072:SF136 RHO FAMILY GTPASE CELL DIVISION CONTROL PROTEIN 42 HOMOLOG GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ion binding#GO:0043167 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cell projection organization#GO:0030030;membrane organization#GO:0061024;transport#GO:0006810;Ras protein signal transduction#GO:0007265;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle organization#GO:0016050;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;endocytosis#GO:0006897;localization of cell#GO:0051674;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;cell projection assembly#GO:0030031;localization#GO:0051179;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;synapse organization#GO:0050808;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cell junction organization#GO:0034330;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 small GTPase#PC00208 CCKR signaling map#P06959>CDC42-GTP#P07155;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;Ras Pathway#P04393>Cdc42#P04569;p38 MAPK pathway#P05918>Cdc42#P06041;Axon guidance mediated by netrin#P00009>cdc42#P00364;Integrin signalling pathway#P00034>Cdc42#P00938;Gonadotropin-releasing hormone receptor pathway#P06664>Cdc42#P06743;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;CCKR signaling map#P06959>CDC42-GDP#P07044;Axon guidance mediated by Slit/Robo#P00008>Cdc42#P00349;T cell activation#P00053>cdc42#P01333 HUMAN|HGNC=51238|UniProtKB=E9PRG8 E9PRG8 C11orf98 PTHR14554:SF1 GENE, 49416-RELATED RCG48016, ISOFORM CRA_C HUMAN|HGNC=12611|UniProtKB=Q92995 Q92995 USP13 PTHR24006:SF682 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=24817|UniProtKB=Q9H5N1 Q9H5N1 RABEP2 PTHR31179:SF6 RAB GTPASE-BINDING EFFECTOR PROTEIN RAB GTPASE-BINDING EFFECTOR PROTEIN 2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=7872|UniProtKB=P29475 P29475 NOS1 PTHR19384:SF63 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE, BRAIN nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;organic cyclic compound binding#GO:0097159;binding#GO:0005488;catalytic activity#GO:0003824;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;cyclic nucleotide metabolic process#GO:0009187;system process#GO:0003008;positive regulation of cellular metabolic process#GO:0031325;purine nucleotide biosynthetic process#GO:0006164;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;nucleoside phosphate metabolic process#GO:0006753;synaptic signaling#GO:0099536;alpha-amino acid metabolic process#GO:1901605;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;response to molecule of bacterial origin#GO:0002237;carboxylic acid catabolic process#GO:0046395;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;purine nucleotide metabolic process#GO:0006163;oxoacid metabolic process#GO:0043436;regulation of lyase activity#GO:0051339;response to oxygen-containing compound#GO:1901700;interspecies interaction between organisms#GO:0044419;trans-synaptic signaling#GO:0099537;organonitrogen compound biosynthetic process#GO:1901566;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;organic acid metabolic process#GO:0006082;ribose phosphate biosynthetic process#GO:0046390;circulatory system process#GO:0003013;response to lipopolysaccharide#GO:0032496;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;organic acid catabolic process#GO:0016054;ribonucleotide biosynthetic process#GO:0009260;small molecule catabolic process#GO:0044282;positive regulation of phosphate metabolic process#GO:0045937;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;cellular amino acid metabolic process#GO:0006520;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;regulation of metabolic process#GO:0019222;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;blood circulation#GO:0008015;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;arginine catabolic process#GO:0006527;regulation of phosphate metabolic process#GO:0019220;second-messenger-mediated signaling#GO:0019932;organophosphate biosynthetic process#GO:0090407;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;response to lipid#GO:0033993;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;response to bacterium#GO:0009617;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;signaling#GO:0023052;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;negative regulation of blood pressure#GO:0045776;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular amino acid catabolic process#GO:0009063;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;carboxylic acid metabolic process#GO:0019752;muscle system process#GO:0003012;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;muscle contraction#GO:0006936 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;organelle membrane#GO:0031090;cytosol#GO:0005829;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;cytoplasm#GO:0005737;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;plasma membrane#GO:0005886 oxidoreductase#PC00176 CCKR signaling map#P06959>NOS1#P07158;Gonadotropin-releasing hormone receptor pathway#P06664>NOSI#P06741;Gonadotropin-releasing hormone receptor pathway#P06664>NOSI#G06888 HUMAN|HGNC=37239|UniProtKB=P0C851 P0C851 PIRT PTHR16100:SF4 PHOSPHOINOSITIDE-INTERACTING PROTEIN FAMILY MEMBER PHOSPHOINOSITIDE-INTERACTING PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;ion channel binding#GO:0044325;protein binding#GO:0005515;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 positive regulation of ion transport#GO:0043270;signal transduction#GO:0007165;transport#GO:0006810;positive regulation of molecular function#GO:0044093;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;positive regulation of transmembrane transport#GO:0034764;phosphatidylinositol-mediated signaling#GO:0048015;regulation of transmembrane transporter activity#GO:0022898;intracellular signal transduction#GO:0035556;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cation channel activity#GO:2001257;cellular response to stimulus#GO:0051716;regulation of transmembrane transport#GO:0034762;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;ion transport#GO:0006811;positive regulation of ion transmembrane transporter activity#GO:0032414;positive regulation of transport#GO:0051050;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;regulation of ion transmembrane transport#GO:0034765;positive regulation of transporter activity#GO:0032411;regulation of cellular process#GO:0050794;positive regulation of ion transmembrane transport#GO:0034767;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;regulation of ion transport#GO:0043269 HUMAN|HGNC=24628|UniProtKB=Q9H204 Q9H204 MED28 PTHR13512:SF2 MEDIATOR COMPLEX SUBUNIT 28 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 28 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=12706|UniProtKB=O95498 O95498 VNN2 PTHR10609:SF15 BIOTINIDASE-RELATED VASCULAR NON-INFLAMMATORY MOLECULE 2 hydrolase#PC00121 HUMAN|HGNC=11871|UniProtKB=P28289 P28289 TMOD1 PTHR10901:SF8 TROPOMODULIN TROPOMODULIN-1 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=8230|UniProtKB=Q6IF42 Q6IF42 OR2A2 PTHR26453:SF82 OLFACTORY RECEPTOR OLFACTORY RECEPTOR-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=6454|UniProtKB=O76013 O76013 KRT36 PTHR23239:SF204 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA6 HUMAN|HGNC=6327|UniProtKB=O60870 O60870 KIN PTHR12805:SF0 KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG DNA/RNA-BINDING PROTEIN KIN17 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16094|UniProtKB=Q86UZ6 Q86UZ6 ZBTB46 PTHR24414:SF63 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 46 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=23147|UniProtKB=Q70J99 Q70J99 UNC13D PTHR45999:SF3 UNC-13-4A, ISOFORM B PROTEIN UNC-13 HOMOLOG D Synaptic vesicle trafficking#P05734>Munc13#P05773 HUMAN|HGNC=15142|UniProtKB=Q9H205 Q9H205 OR2AG1 PTHR26453:SF183 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AG1 transmembrane signal receptor#PC00197 HUMAN|HGNC=2960|UniProtKB=O00115 O00115 DNASE2 PTHR10858:SF9 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE-2-ALPHA hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;endodeoxyribonuclease activity#GO:0004520;deoxyribonuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;heterocycle catabolic process#GO:0046700;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;plasma membrane bounded cell projection organization#GO:0120036;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;DNA catabolic process, endonucleolytic#GO:0000737;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;cell projection assembly#GO:0030031;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;plasma membrane bounded cell projection assembly#GO:0120031;DNA metabolic process#GO:0006259 endodeoxyribonuclease#PC00093 HUMAN|HGNC=14461|UniProtKB=Q8WTU2 Q8WTU2 SSC4D PTHR19331:SF439 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING GROUP B PROTEIN serine protease#PC00203 HUMAN|HGNC=33756|UniProtKB=A6NH11 A6NH11 GLTPD2 PTHR10219:SF19 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 transfer/carrier protein#PC00219 HUMAN|HGNC=18570|UniProtKB=Q8IUE1 Q8IUE1 TGIF2LX PTHR11850:SF205 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF2LX-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=14131|UniProtKB=Q9P2W3 Q9P2W3 GNG13 PTHR15936:SF2 GUANINE NUCLEOTIDE-BINDING PROTEIN G I /G S /G O GAMMA-13 SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-13 heterotrimeric G-protein#PC00117 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 HUMAN|HGNC=7162|UniProtKB=P51512 P51512 MMP16 PTHR10201:SF26 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-16 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;extracellular structure organization#GO:0043062;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;skeletal system development#GO:0001501;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=24008|UniProtKB=Q5JRA6 Q5JRA6 MIA3 PTHR23158:SF54 MELANOMA INHIBITORY ACTIVITY-RELATED TRANSPORT AND GOLGI ORGANIZATION PROTEIN 1 HOMOLOG endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=11776|UniProtKB=Q15583 Q15583 TGIF1 PTHR11850:SF59 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>TGIF1#P06725 HUMAN|HGNC=23795|UniProtKB=Q9BZ81 Q9BZ81 MAGEB5 PTHR11736:SF35 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B5 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17071|UniProtKB=Q9H3R0 Q9H3R0 KDM4C PTHR10694:SF104 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4C 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=6201|UniProtKB=O76095 O76095 JTB PTHR13041:SF3 JTB PROTEIN-RELATED PROTEIN JTB cell division#GO:0051301;membrane fission#GO:0090148;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;organelle organization#GO:0006996;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;cytokinesis#GO:0000910 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;centrosome#GO:0005813 HUMAN|HGNC=26006|UniProtKB=Q6DKK2 Q6DKK2 TTC19 PTHR13143:SF6 TETRATRICOPEPTIDE REPEAT PROTEIN 19 TETRATRICOPEPTIDE REPEAT PROTEIN 19, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=34343|UniProtKB=Q6ZV65 Q6ZV65 FAM47E PTHR46449:SF3 ZGC:158260 PROTEIN FAM47E HUMAN|HGNC=1723|UniProtKB=Q12834 Q12834 CDC20 PTHR19918:SF3 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;regulation of cellular protein catabolic process#GO:1903362;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9661|UniProtKB=P43378 P43378 PTPN9 PTHR19134:SF285 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 9 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=1787|UniProtKB=P42771 P42771 CDKN2A PTHR24201:SF4 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE INHIBITOR 2A p53 pathway#P00059>ARF#G01574;p53 pathway#P00059>ARF#P01482 HUMAN|HGNC=26859|UniProtKB=Q8N7X1 Q8N7X1 RBMXL3 PTHR13952:SF11 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD RNA-BINDING MOTIF PROTEIN, X-LINKED-LIKE-2-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U12-type spliceosomal complex#GO:0005689 RNA splicing factor#PC00148 HUMAN|HGNC=26545|UniProtKB=A6NI28 A6NI28 ARHGAP42 PTHR12552:SF3 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 42 GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=23620|UniProtKB=Q9H665 Q9H665 IGFLR1 PTHR14657:SF2 IGF-LIKE FAMILY RECEPTOR 1 IGF-LIKE FAMILY RECEPTOR 1 transmembrane signal receptor#PC00197 HUMAN|HGNC=20900|UniProtKB=Q9UJA5 Q9UJA5 TRMT6 PTHR12945:SF0 TRANSLATION INITIATION FACTOR EIF3-RELATED TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6 tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA (adenine) methyltransferase activity#GO:0016426;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 translation initiation factor#PC00224 HUMAN|HGNC=3772|UniProtKB=P31512 P31512 FMO4 PTHR23023:SF74 DIMETHYLANILINE MONOOXYGENASE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 oxygenase#PC00177 HUMAN|HGNC=29167|UniProtKB=Q9Y2K5 Q9Y2K5 R3HDM2 PTHR15672:SF13 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN R3H DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=17264|UniProtKB=O95602 O95602 POLR1A PTHR19376:SF11 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=23429|UniProtKB=Q5JSS6 Q5JSS6 MEIG1 PTHR17008:SF1 MEIOSIS-EXPRESSED GENE 1 PROTEIN MEIOSIS EXPRESSED GENE 1 PROTEIN HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=7626|UniProtKB=Q13506 Q13506 NAB1 PTHR12623:SF9 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 Gonadotropin-releasing hormone receptor pathway#P06664>NAB#P06801 HUMAN|HGNC=620|UniProtKB=P05067 P05067 APP PTHR23103:SF7 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID-BETA PRECURSOR PROTEIN protease inhibitor#PC00191 Blood coagulation#P00011>PN2#P00429;Alzheimer disease-amyloid secretase pathway#P00003>C99#P00106;Alzheimer disease-amyloid secretase pathway#P00003>p3#P00086;Alzheimer disease-amyloid secretase pathway#P00003>Abeta#P00096;Alzheimer disease-amyloid secretase pathway#P00003>C83#P00100;Alzheimer disease-amyloid secretase pathway#P00003>AICD#P00080;Alzheimer disease-amyloid secretase pathway#P00003>APP#P00085;Alzheimer disease-presenilin pathway#P00004>APPbeta#P00151;Alzheimer disease-amyloid secretase pathway#P00003>APPalpha#P00097;Alzheimer disease-presenilin pathway#P00004>APP#P00127;Alzheimer disease-amyloid secretase pathway#P00003>APPbeta#P00104;Alzheimer disease-presenilin pathway#P00004>C99#P00111;Alzheimer disease-presenilin pathway#P00004>AICD#P00166;Alzheimer disease-presenilin pathway#P00004>Abeta#P00136 HUMAN|HGNC=1767|UniProtKB=P55286 P55286 CDH8 PTHR24027:SF273 CADHERIN-23 CADHERIN-8 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chemical synaptic transmission#GO:0007268;anatomical structure morphogenesis#GO:0009653;anterograde trans-synaptic signaling#GO:0098916;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell junction assembly#GO:0034329;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;extracellular region#GO:0005576;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;adherens junction#GO:0005912;cell projection#GO:0042995;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=17179|UniProtKB=Q7L3B6 Q7L3B6 CDC37L1 PTHR12800:SF2 CDC37-RELATED HSP90 CO-CHAPERONE CDC37-LIKE 1 protein binding#GO:0005515;heat shock protein binding#GO:0031072;unfolded protein binding#GO:0051082;binding#GO:0005488;chaperone binding#GO:0051087 biological regulation#GO:0065007;regulation of protein stability#GO:0031647;cellular process#GO:0009987;regulation of biological quality#GO:0065008;protein folding#GO:0006457;protein stabilization#GO:0050821 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=20399|UniProtKB=Q9NYZ1 Q9NYZ1 TVP23B PTHR13019:SF9 UNCHARACTERIZED GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG B macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=17512|UniProtKB=Q86YM7 Q86YM7 HOMER1 PTHR10918:SF3 HOMER HOMER PROTEIN HOMOLOG 1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;metal ion transport#GO:0030001;regulation of metal ion transport#GO:0010959;ion transport#GO:0006811;transport#GO:0006810;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;cell communication#GO:0007154;cation transport#GO:0006812;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;calcium ion transport#GO:0006816;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;divalent inorganic cation transport#GO:0072511;G protein-coupled receptor signaling pathway#GO:0007186;regulation of ion transport#GO:0043269;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;postsynaptic density#GO:0014069;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;asymmetric synapse#GO:0032279;cytoplasm#GO:0005737;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 Metabotropic glutamate receptor group I pathway#P00041>Homer#P01058 HUMAN|HGNC=30790|UniProtKB=Q96PF1 Q96PF1 TGM7 PTHR11590:SF41 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE Z transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular protein modification process#GO:0006464 transferase#PC00220 HUMAN|HGNC=6286|UniProtKB=Q9Y691 Q9Y691 KCNMB2 PTHR10258:SF5 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;transporter activity#GO:0005215;channel activity#GO:0015267;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 response to metal ion#GO:0010038;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to inorganic substance#GO:0010035;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=6563|UniProtKB=P17931 P17931 LGALS3 PTHR11346:SF26 GALECTIN GALECTIN-3 extracellular matrix binding#GO:0050840;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488 membrane organization#GO:0061024;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of apoptotic signaling pathway#GO:2001233;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;divalent inorganic cation transport#GO:0072511;negative regulation of cellular component organization#GO:0051129;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;regulation of endocytosis#GO:0030100;macrophage chemotaxis#GO:0048246;negative regulation of apoptotic signaling pathway#GO:2001234;endocytosis#GO:0006897;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of calcium ion transport#GO:0051924;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;positive regulation of transport#GO:0051050;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of transport#GO:0051051;calcium ion import#GO:0070509;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;movement of cell or subcellular component#GO:0006928;negative regulation of signal transduction#GO:0009968;regulation of ion transport#GO:0043269;positive chemotaxis#GO:0050918;locomotion#GO:0040011;taxis#GO:0042330;positive regulation of ion transport#GO:0043270;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of signaling#GO:0023051;transport#GO:0006810;cation transport#GO:0006812;calcium ion transport#GO:0006816;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;granulocyte chemotaxis#GO:0071621;negative regulation of programmed cell death#GO:0043069;myeloid leukocyte migration#GO:0097529;cell death#GO:0008219;vesicle organization#GO:0016050;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;neutrophil migration#GO:1990266;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of calcium ion transport#GO:0051928;negative regulation of apoptotic process#GO:0043066;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;response to chemical#GO:0042221;extrinsic apoptotic signaling pathway#GO:0097191;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell migration#GO:0016477 extracellular matrix#GO:0031012;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;collagen-containing extracellular matrix#GO:0062023;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 extracellular matrix protein#PC00102 HUMAN|HGNC=18451|UniProtKB=Q8NI22 Q8NI22 MCFD2 PTHR23104:SF14 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 membrane traffic protein#PC00150 HUMAN|HGNC=41989|UniProtKB=A6NJU9 A6NJU9 NPIPB13 PTHR15438:SF5 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER B11-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=391|UniProtKB=P31749 P31749 AKT1 PTHR24356:SF171 SERINE/THREONINE-PROTEIN KINASE RAC-ALPHA SERINE/THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 Ras Pathway#P04393>AKT#P04570;Angiogenesis#P00005>Akt#P00223;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AKT#P00827;p53 pathway#P00059>Akt#P01486;Interleukin signaling pathway#P00036>PKB#P00973;Huntington disease#P00029>Akt#P00805;CCKR signaling map#P06959>AKT1#P07152;Apoptosis signaling pathway#P00006>AKT#P00260;p53 pathway by glucose deprivation#P04397>Akt#P04641;FGF signaling pathway#P00021>Akt#P00632;VEGF signaling pathway#P00056>Akt/PKB#P01408;p53 pathway feedback loops 2#P04398>AKT#P04665;EGF receptor signaling pathway#P00018>Akt#P00551;Hypoxia response via HIF activation#P00030>AKT#P00819;T cell activation#P00053>Akt#P01332;PI3 kinase pathway#P00048>PKB#P01179;FAS signaling pathway#P00020>ASK1#P00614;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>AKT#P00894;Gonadotropin-releasing hormone receptor pathway#P06664>AKT#P06779;Endothelin signaling pathway#P00019>Akt#P00589 HUMAN|HGNC=25813|UniProtKB=Q7Z2Y8 Q7Z2Y8 GVINP1 PTHR14819:SF5 GTP-BINDING INTERFERON-INDUCED VERY LARGE GTPASE 1 HUMAN|HGNC=8705|UniProtKB=Q9Y5G6 Q9Y5G6 PCDHGA7 PTHR24028:SF56 CADHERIN-87A PROTOCADHERIN GAMMA-A7 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=2906|UniProtKB=Q9P1A6 Q9P1A6 DLGAP2 PTHR12353:SF3 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 2 molecular adaptor activity#GO:0060090;binding#GO:0005488 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;regulation of neurotransmitter receptor activity#GO:0099601;chemical synaptic transmission, postsynaptic#GO:0099565;system process#GO:0003008;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;regulation of system process#GO:0044057;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;signaling#GO:0023052 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;postsynapse#GO:0098794;synapse#GO:0045202;postsynaptic specialization#GO:0099572;cellular anatomical entity#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20774|UniProtKB=P04350 P04350 TUBB4A PTHR11588:SF253 TUBULIN TUBULIN BETA-4A CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 HUMAN|HGNC=6235|UniProtKB=Q14003 Q14003 KCNC3 PTHR11537:SF184 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;cell leading edge#GO:0031252;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;cell body#GO:0044297;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=18743|UniProtKB=Q96PV4 Q96PV4 PNMA5 PTHR23095:SF4 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 5 HUMAN|HGNC=19161|UniProtKB=Q92502 Q92502 STARD8 PTHR12659:SF3 RHO-TYPE GTPASE ACTIVATING PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 8 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;Rho protein signal transduction#GO:0007266;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;actin cytoskeleton organization#GO:0030036;signaling#GO:0023052;regulation of Ras protein signal transduction#GO:0046578 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=6856|UniProtKB=Q9Y6R4 Q9Y6R4 MAP3K4 PTHR48016:SF32 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 4 non-receptor serine/threonine protein kinase#PC00167 Interleukin signaling pathway#P00036>MEK#P00984;Integrin signalling pathway#P00034>ERK#P00907;PDGF signaling pathway#P00047>ERK#P01143;FGF signaling pathway#P00021>MEKK1-5#P00634;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;p38 MAPK pathway#P05918>MEKK4#P06026;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MEK#P00864;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Oxidative stress response#P00046>MKK4#P01138;Ras Pathway#P04393>MEKK1/4#P04543 HUMAN|HGNC=21086|UniProtKB=Q86YT6 Q86YT6 MIB1 PTHR24202:SF52 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB1 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 signal transduction#GO:0007165;macromolecule modification#GO:0043412;membrane organization#GO:0061024;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein modification process#GO:0036211;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;vesicle organization#GO:0016050;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;Notch signaling pathway#GO:0007219 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=25446|UniProtKB=Q69YI7 Q69YI7 NAIF1 PTHR23098:SF7 AGAP001331-PA-RELATED NUCLEAR APOPTOSIS-INDUCING FACTOR 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=9003|UniProtKB=O00562 O00562 PITPNM1 PTHR10658:SF40 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN MEMBRANE-ASSOCIATED PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 1 cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transporter#PC00227 HUMAN|HGNC=23526|UniProtKB=Q8NE86 Q8NE86 MCU PTHR13462:SF16 CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;mitochondrial calcium ion homeostasis#GO:0051560;mitochondrial transmembrane transport#GO:1990542;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;mitochondrial transport#GO:0006839;cellular chemical homeostasis#GO:0055082;mitochondrial calcium ion transmembrane transport#GO:0006851;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 integral component of mitochondrial inner membrane#GO:0031305;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intrinsic component of mitochondrial inner membrane#GO:0031304;ion channel complex#GO:0034702;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;membrane#GO:0016020;cation channel complex#GO:0034703;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of mitochondrial membrane#GO:0098573;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=16813|UniProtKB=Q86WC6 Q86WC6 PPP1R27 PTHR46899:SF3 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 27 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 27 phosphatase modulator#PC00184 HUMAN|HGNC=5475|UniProtKB=P24592 P24592 IGFBP6 PTHR11551:SF14 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 6 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=20327|UniProtKB=Q5T8P6 Q5T8P6 RBM26 PTHR14398:SF2 RNA RECOGNITION RRM/RNP DOMAIN RNA-BINDING PROTEIN 26 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;positive regulation of cellular process#GO:0048522;RNA localization#GO:0006403;localization#GO:0051179;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;positive regulation of biological process#GO:0048518;nuclear transport#GO:0051169 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=19824|UniProtKB=O95926 O95926 SYF2 PTHR13264:SF5 GCIP-INTERACTING PROTEIN P29 PRE-MRNA-SPLICING FACTOR SYF2 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=26323|UniProtKB=Q8N283 Q8N283 ANKRD35 PTHR24161:SF21 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 35 HUMAN|HGNC=17931|UniProtKB=Q9UJW9 Q9UJW9 SERTAD3 PTHR15530:SF0 SERTA DOMAIN-CONTAINING PROTEIN 3 SERTA DOMAIN-CONTAINING PROTEIN 3 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12566|UniProtKB=O14795 O14795 UNC13B PTHR10480:SF8 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG B syntaxin binding#GO:0019905;protein binding#GO:0005515;calmodulin binding#GO:0005516;SNARE binding#GO:0000149;binding#GO:0005488;syntaxin-1 binding#GO:0017075 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;regulated exocytosis#GO:0045055;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;neuromuscular junction development#GO:0007528;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of neurotransmitter levels#GO:0001505;cell junction organization#GO:0034330;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;synaptic transmission, glutamatergic#GO:0035249;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;terminal bouton#GO:0043195;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;presynaptic membrane#GO:0042734;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;neuromuscular junction#GO:0031594;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell cortex#GO:0005938;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;whole membrane#GO:0098805;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 Synaptic vesicle trafficking#P05734>Munc13#P05773 HUMAN|HGNC=4715|UniProtKB=Q02539 Q02539 H1-1 PTHR11467:SF153 HISTONE H1 HISTONE H1.1 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of chromatin silencing#GO:0031935;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of chromatin silencing#GO:0031936;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of chromatin organization#GO:1902275;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;chromosome condensation#GO:0030261;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of DNA recombination#GO:0000018;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone#PC00118 HUMAN|HGNC=25417|UniProtKB=Q8N4V2 Q8N4V2 SVOP PTHR24064:SF445 SOLUTE CARRIER FAMILY 22 MEMBER SYNAPTIC VESICLE 2-RELATED PROTEIN secondary carrier transporter#PC00258 HUMAN|HGNC=816|UniProtKB=Q16720 Q16720 ATP2B3 PTHR24093:SF284 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 3 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;binding#GO:0005488;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=7866|UniProtKB=Q13253 Q13253 NOG PTHR10494:SF5 BONE MORPHOGENETIC PROTEIN INHIBITOR, NOGGIN NOGGIN signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;negative regulation of cellular response to growth factor stimulus#GO:0090288;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;pattern specification process#GO:0007389;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;ossification#GO:0001503;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=1313|UniProtKB=Q9NWS6 Q9NWS6 FAM118A PTHR28623:SF2 PROTEIN FAM118B PROTEIN FAM118A HUMAN|HGNC=9659|UniProtKB=P35236 P35236 PTPN7 PTHR19134:SF41 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=10548|UniProtKB=P54253 P54253 ATXN1 PTHR13392:SF5 ATAXIN 1 ATAXIN-1 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=6623|UniProtKB=Q9Y5X9 Q9Y5X9 LIPG PTHR11610:SF13 LIPASE ENDOTHELIAL LIPASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid catabolic process#GO:0044242;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;triglyceride metabolic process#GO:0006641;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerolipid catabolic process#GO:0046503;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143 HUMAN|HGNC=1460|UniProtKB=Q9UQM7 Q9UQM7 CAMK2A PTHR24347:SF384 SERINE/THREONINE-PROTEIN KINASE CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 HUMAN|Ensembl=ENSG00000283378|UniProtKB=A0A1B0GTE1 A0A1B0GTE1 CNTNAP3C PTHR15036:SF36 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN FAMILY MEMBER 3C-RELATED HUMAN|HGNC=25554|UniProtKB=Q96CQ1 Q96CQ1 SLC25A36 PTHR45829:SF2 MITOCHONDRIAL CARRIER PROTEIN RIM2 SOLUTE CARRIER FAMILY 25 MEMBER 36 organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;nucleotide transmembrane transporter activity#GO:0015215;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleotide transport#GO:0006862;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;nucleotide transmembrane transport#GO:1901679;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542 mitochondrial carrier protein#PC00158 HUMAN|HGNC=12623|UniProtKB=Q9UPU5 Q9UPU5 USP24 PTHR24006:SF729 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 24 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=30362|UniProtKB=Q8IVN8 Q8IVN8 SBSPON PTHR20920:SF2 RPE-SPONDIN SOMATOMEDIN-B AND THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=5651|UniProtKB=P01824 P01824 IGHV4-39 PTHR23266:SF323 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=28628|UniProtKB=Q8N5I9 Q8N5I9 C12orf45 PTHR28674:SF1 SIMILAR TO DNA SEGMENT, CHR 10, WAYNE STATE UNIVERSITY 102,-EXPRESSED SIMILAR TO DNA SEGMENT, CHR 10, WAYNE STATE UNIVERSITY 102,-EXPRESSED HUMAN|HGNC=24970|UniProtKB=Q0D2I5 Q0D2I5 IFFO1 PTHR14516:SF2 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER INTERMEDIATE FILAMENT FAMILY ORPHAN 1 dehydrogenase#PC00092 HUMAN|HGNC=12681|UniProtKB=P49765 P49765 VEGFB PTHR12025:SF12 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR B receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein metabolic process#GO:0051246;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;positive regulation of protein modification process#GO:0031401;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;tube morphogenesis#GO:0035239;epithelial cell proliferation#GO:0050673;sprouting angiogenesis#GO:0002040;positive regulation of epithelial cell proliferation#GO:0050679;cellular protein metabolic process#GO:0044267;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;angiogenesis#GO:0001525;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;taxis#GO:0042330;signal transduction#GO:0007165;response to hypoxia#GO:0001666;positive regulation of angiogenesis#GO:0045766;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of leukocyte migration#GO:0002687;system development#GO:0048731;regulation of chemotaxis#GO:0050920;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;myeloid leukocyte migration#GO:0097529;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;response to oxygen levels#GO:0070482;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;positive regulation of immune system process#GO:0002684;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cell chemotaxis#GO:0060326;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;positive regulation of cellular component movement#GO:0051272;regulation of phosphorus metabolic process#GO:0051174;leukocyte migration#GO:0050900;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;nitrogen compound metabolic process#GO:0006807;vasculature development#GO:0001944;response to abiotic stimulus#GO:0009628;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;response to decreased oxygen levels#GO:0036293;tube development#GO:0035295;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;positive chemotaxis#GO:0050918;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;developmental process#GO:0032502;endothelial cell proliferation#GO:0001935;regulation of angiogenesis#GO:0045765;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;positive regulation of developmental process#GO:0051094;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of leukocyte chemotaxis#GO:0002690;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|Ensembl=ENSG00000283140|UniProtKB=A0A1B0GTQ1 A0A1B0GTQ1 CYP2D7 PTHR24300:SF1 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2D6-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=26827|UniProtKB=Q2QL34 Q2QL34 MPV17L PTHR11266:SF39 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=4189|UniProtKB=Q92947 Q92947 GCDH PTHR42807:SF1 GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092 HUMAN|HGNC=8743|UniProtKB=P29120 P29120 PCSK1 PTHR42884:SF14 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 1 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;protein metabolic process#GO:0019538;protein processing#GO:0016485;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 serine protease#PC00203 Endothelin signaling pathway#P00019>furin#P00575;Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 HUMAN|HGNC=1484|UniProtKB=Q9Y6W3 Q9Y6W3 CAPN7 PTHR46143:SF1 CALPAIN-7 CALPAIN-7 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=26406|UniProtKB=Q96NL6 Q96NL6 SCLT1 PTHR35970:SF1 SODIUM CHANNEL AND CLATHRIN LINKER 1 SODIUM CHANNEL AND CLATHRIN LINKER 1 HUMAN|HGNC=19657|UniProtKB=Q7RTS6 Q7RTS6 OTOP2 PTHR21522:SF35 PROTON CHANNEL OTOP PROTON CHANNEL OTOP2 transporter#PC00227 HUMAN|HGNC=16046|UniProtKB=Q53HI1 Q53HI1 UNC50 PTHR12841:SF6 PROTEIN UNC-50 HOMOLOG PROTEIN UNC-50 HOMOLOG localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=24074|UniProtKB=Q5VWM4 Q5VWM4 PRAMEF8 PTHR14224:SF30 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 7-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=25985|UniProtKB=Q5H8A4 Q5H8A4 PIGG PTHR23072:SF0 PHOSPHATIDYLINOSITOL GLYCAN-RELATED GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=28814|UniProtKB=Q96DC7 Q96DC7 TMCO6 PTHR16356:SF1 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 TMCO6 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 HUMAN|HGNC=20567|UniProtKB=O75414 O75414 NME6 PTHR46956:SF1 NUCLEOSIDE DIPHOSPHATE KINASE 6 NUCLEOSIDE DIPHOSPHATE KINASE 6 kinase#PC00137 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 HUMAN|HGNC=44659|UniProtKB=Q96MC4 Q96MC4 CEP295NL PTHR21553:SF33 ALMS1-RELATED CEP295 N-TERMINAL-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;regulation of centrosome duplication#GO:0010824 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=20581|UniProtKB=Q9NR63 Q9NR63 CYP26B1 PTHR24286:SF177 CYTOCHROME P450 26 CYTOCHROME P450 26B1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;oxidation-reduction process#GO:0055114;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177 HUMAN|HGNC=19023|UniProtKB=Q9BSJ1 Q9BSJ1 TRIM51 PTHR24103:SF574 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 51 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=29435|UniProtKB=Q8IX03 Q8IX03 WWC1 PTHR14791:SF22 BOMB/KIRA PROTEINS PROTEIN KIBRA HUMAN|HGNC=27015|UniProtKB=Q5EBM0 Q5EBM0 CMPK2 PTHR10344:SF4 THYMIDYLATE KINASE UMP-CMP KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;pyrimidine nucleotide biosynthetic process#GO:0006221;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotide kinase#PC00172 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916 HUMAN|HGNC=736|UniProtKB=Q02083 Q02083 NAAA PTHR28583:SF4 ACID AMIDASE N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cysteine protease#PC00081 HUMAN|HGNC=9118|UniProtKB=Q01453 Q01453 PMP22 PTHR10671:SF7 EPITHELIAL MEMBRANE PROTEIN-RELATED PERIPHERAL MYELIN PROTEIN 22 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=12140|UniProtKB=A0A0B4J268 A0A0B4J268 TRAV4 PTHR19433:SF130 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 4 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=16083|UniProtKB=Q9NX52 Q9NX52 RHBDL2 PTHR45840:SF6 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 2 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 HUMAN|HGNC=5949|UniProtKB=Q93033 Q93033 CD101 PTHR12207:SF25 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 2 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=6917|UniProtKB=Q9UBB5 Q9UBB5 MBD2 PTHR12396:SF5 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 2 HUMAN|HGNC=6421|UniProtKB=P19012 P19012 KRT15 PTHR23239:SF164 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 15 HUMAN|HGNC=10069|UniProtKB=Q9Y252 Q9Y252 RNF6 PTHR45931:SF2 SI:CH211-59O9.10 E3 UBIQUITIN-PROTEIN LIGASE RNF6 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;positive regulation of transcription, DNA-templated#GO:0045893;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14078|UniProtKB=Q9BYV9 Q9BYV9 BACH2 PTHR46105:SF8 AGAP004733-PA TRANSCRIPTION REGULATOR PROTEIN BACH2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=662|UniProtKB=Q13795 Q13795 ARFRP1 PTHR45909:SF1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=8926|UniProtKB=P46019 P46019 PHKA2 PTHR10749:SF5 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA, LIVER ISOFORM cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 HUMAN|HGNC=21715|UniProtKB=Q7Z442 Q7Z442 PKD1L2 PTHR10877:SF134 POLYCYSTIN FAMILY MEMBER POLYCYSTIC KIDNEY DISEASE PROTEIN 1-LIKE 2 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133 HUMAN|HGNC=13356|UniProtKB=Q9GZU1 Q9GZU1 MCOLN1 PTHR12127:SF6 MUCOLIPIN MUCOLIPIN-1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=19855|UniProtKB=Q8ND07 Q8ND07 BBOF1 PTHR14845:SF5 COILED-COIL DOMAIN-CONTAINING 166 BASAL BODY-ORIENTATION FACTOR 1 HUMAN|HGNC=25242|UniProtKB=P69849 P69849 NOMO3 PTHR23303:SF14 CARBOXYPEPTIDASE REGULATORY REGION-CONTAINING NODAL MODULATOR 1-RELATED cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=19011|UniProtKB=Q8IZF3 Q8IZF3 ADGRF4 PTHR45813:SF1 FAMILY NOT NAMED ADHESION G PROTEIN-COUPLED RECEPTOR F4 HUMAN|HGNC=1080|UniProtKB=P05423 P05423 POLR3D PTHR13408:SF0 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;intracellular#GO:0005622;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;transferase complex#GO:1990234;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=20471|UniProtKB=O95777 O95777 LSM8 PTHR15588:SF9 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=6113|UniProtKB=O43187 O43187 IRAK2 PTHR24419:SF2 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE-LIKE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;response to interleukin-1#GO:0070555;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=20692|UniProtKB=Q8IWU9 Q8IWU9 TPH2 PTHR11473:SF16 AROMATIC AMINO ACID HYDROXYLASE TRYPTOPHAN 5-HYDROXYLASE 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 5-Hydroxytryptamine biosynthesis#P04371>Tryptophan hydroxylase#P04399 HUMAN|HGNC=15769|UniProtKB=Q9NPB1 Q9NPB1 NT5M PTHR16504:SF6 5'(3')-DEOXYRIBONUCLEOTIDASE 5'(3')-DEOXYRIBONUCLEOTIDASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;nucleotidase activity#GO:0008252 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 HUMAN|HGNC=30023|UniProtKB=Q8WW12 Q8WW12 PCNP PTHR16523:SF8 PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=15581|UniProtKB=Q7Z6R9 Q7Z6R9 TFAP2D PTHR10812:SF5 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-DELTA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 general transcription factor#PC00259 HUMAN|HGNC=7751|UniProtKB=Q99435 Q99435 NELL2 PTHR24042:SF0 NEL HOMOLOG PROTEIN KINASE C-BINDING PROTEIN NELL2 calcium-binding protein#PC00060 HUMAN|HGNC=11825|UniProtKB=P43699 P43699 NKX2-1 PTHR24340:SF33 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=29010|UniProtKB=O15047 O15047 SETD1A PTHR45814:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1A histone modifying enzyme#PC00261 HUMAN|HGNC=17315|UniProtKB=Q99595 Q99595 TIMM17A PTHR10485:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-A protein transmembrane transporter activity#GO:0008320;amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 transporter#PC00227 HUMAN|HGNC=23063|UniProtKB=Q9NV35 Q9NV35 NUDT15 PTHR16099:SF5 8-OXO-DGTP DIPHOSPHATES NUDT15 NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15 HUMAN|HGNC=291|UniProtKB=P30566 P30566 ADSL PTHR43172:SF1 ADENYLOSUCCINATE LYASE ADENYLOSUCCINATE LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;AMP metabolic process#GO:0046033;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 lyase#PC00144 De novo purine biosynthesis#P02738>Adenosuccinate lyase#P02901;De novo purine biosynthesis#P02738>5-Phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole lyase#P02892 HUMAN|HGNC=17887|UniProtKB=Q9UQ10 Q9UQ10 DHDH PTHR22604:SF105 OXIDOREDUCTASES TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE oxidoreductase#PC00176 HUMAN|HGNC=16940|UniProtKB=Q96PD7 Q96PD7 DGAT2 PTHR12317:SF14 DIACYLGLYCEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=282|UniProtKB=P18089 P18089 ADRA2B PTHR24248:SF130 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2B ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 HUMAN|HGNC=3750|UniProtKB=Q13045 Q13045 FLII PTHR11977:SF122 VILLIN PROTEIN FLIGHTLESS-1 HOMOLOG cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;muscle cell differentiation#GO:0042692;cellular protein complex disassembly#GO:0043624;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;myofibril assembly#GO:0030239;regulation of actin polymerization or depolymerization#GO:0008064;muscle structure development#GO:0061061;regulation of biological process#GO:0050789;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;protein depolymerization#GO:0051261;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of actin filament polymerization#GO:0030833;cellular component morphogenesis#GO:0032989;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;organelle assembly#GO:0070925;cell development#GO:0048468;regulation of supramolecular fiber organization#GO:1902903;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;anatomical structure development#GO:0048856;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;actin cytoskeleton#GO:0015629;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=237|UniProtKB=O43306 O43306 ADCY6 PTHR45627:SF11 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 6 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of adenylate cyclase activity#GO:0045761;cyclic nucleotide metabolic process#GO:0009187;purine nucleotide biosynthetic process#GO:0006164;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;negative regulation of signaling#GO:0023057;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cAMP-mediated signaling#GO:0019933;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;carbohydrate derivative metabolic process#GO:1901135;second-messenger-mediated signaling#GO:0019932;organophosphate biosynthetic process#GO:0090407;regulation of cyclase activity#GO:0031279;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;purine ribonucleotide biosynthetic process#GO:0009152;negative regulation of molecular function#GO:0044092;nucleobase-containing small molecule metabolic process#GO:0055086;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 HUMAN|HGNC=668|UniProtKB=P62745 P62745 RHOB PTHR24072:SF0 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOB GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 small GTPase#PC00208 Ras Pathway#P04393>Rho#P04578;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507;PDGF signaling pathway#P00047>Ras#P01154 HUMAN|HGNC=28990|UniProtKB=Q92618 Q92618 ZNF516 PTHR45925:SF3 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 516 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=18600|UniProtKB=Q96RT8 Q96RT8 TUBGCP5 PTHR19302:SF33 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 5 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;reproductive process#GO:0022414;spindle assembly#GO:0051225;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cytoplasmic microtubule organization#GO:0031122;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;protein polymerization#GO:0051258;organelle fission#GO:0048285;cell cycle#GO:0007049 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;intracellular#GO:0005622;gamma-tubulin complex#GO:0000930;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=7748|UniProtKB=Q6P3R8 Q6P3R8 NEK5 PTHR44899:SF1 CAMK FAMILY PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE NEK5 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=10876|UniProtKB=Q9Y286 Q9Y286 SIGLEC7 PTHR12035:SF111 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 7 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|Ensembl=ENSG00000253251|UniProtKB=Q6ZNX1 Q6ZNX1 SHLD3 PTHR41404:SF1 SHIELDIN COMPLEX SUBUNIT 3 SHIELDIN COMPLEX SUBUNIT 3 DNA repair#GO:0006281;negative regulation of response to DNA damage stimulus#GO:2001021;regulation of double-strand break repair#GO:2000779;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;lymphocyte mediated immunity#GO:0002449;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;production of molecular mediator of immune response#GO:0002440;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;recombinational repair#GO:0000725;positive regulation of immune effector process#GO:0002699;B cell activation#GO:0042113;regulation of adaptive immune response#GO:0002819;somatic diversification of immune receptors#GO:0002200;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;B cell activation involved in immune response#GO:0002312;organic substance metabolic process#GO:0071704;lymphocyte activation involved in immune response#GO:0002285;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;regulation of immune response#GO:0050776;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;positive regulation of lymphocyte mediated immunity#GO:0002708;negative regulation of nitrogen compound metabolic process#GO:0051172;DNA recombination#GO:0006310;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;double-strand break repair via nonhomologous end joining#GO:0006303;response to stress#GO:0006950;leukocyte activation involved in immune response#GO:0002366;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of production of molecular mediator of immune response#GO:0002700;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of double-strand break repair via homologous recombination#GO:2000042;positive regulation of cell activation#GO:0050867;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of DNA repair#GO:0045739;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;negative regulation of DNA repair#GO:0045738;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of DNA repair#GO:0006282;positive regulation of adaptive immune response#GO:0002821;regulation of multicellular organismal development#GO:2000026;regulation of double-strand break repair via homologous recombination#GO:0010569;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;somatic recombination of immunoglobulin gene segments#GO:0016447;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;somatic cell DNA recombination#GO:0016444;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immunoglobulin mediated immune response#GO:0002891;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;immune effector process#GO:0002252;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;immunoglobulin production#GO:0002377;negative regulation of response to stimulus#GO:0048585;lymphocyte activation#GO:0046649;immune response#GO:0006955;multicellular organism development#GO:0007275;leukocyte mediated immunity#GO:0002443;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;non-recombinational repair#GO:0000726;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of immune effector process#GO:0002697;regulation of leukocyte activation#GO:0002694;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of double-strand break repair#GO:2000780;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of immunoglobulin production#GO:0002639;regulation of DNA recombination#GO:0000018;DNA metabolic process#GO:0006259 HUMAN|HGNC=22957|UniProtKB=Q496A3 Q496A3 SPATS1 PTHR35845:SF1 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 1 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 1 HUMAN|HGNC=28606|UniProtKB=Q0VDE8 Q0VDE8 ADIG PTHR38499:SF1 ADIPOGENIN ADIPOGENIN HUMAN|HGNC=30346|UniProtKB=Q9NYV6 Q9NYV6 RRN3 PTHR12790:SF0 TRANSCRIPTION INITIATION FACTOR IA RRN3 RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 HUMAN|HGNC=11276|UniProtKB=O15020 O15020 SPTBN2 PTHR11915:SF325 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 2 HUMAN|HGNC=10534|UniProtKB=Q9NR31 Q9NR31 SAR1A PTHR45684:SF6 RE74312P GTP-BINDING PROTEIN SAR1A pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 vesicle targeting, to, from or within Golgi#GO:0048199;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;Golgi vesicle budding#GO:0048194;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;establishment of vesicle localization#GO:0051650;vesicle organization#GO:0016050;regulation of protein transport#GO:0051223;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of protein localization#GO:0032880;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;vesicle localization#GO:0051648;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;regulation of cellular localization#GO:0060341;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=31957|UniProtKB=Q13066 Q13066 GAGE2B PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=1615|UniProtKB=P78371 P78371 CCT2 PTHR11353:SF23 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT BETA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;chaperone complex#GO:0101031;cellular anatomical entity#GO:0110165;chaperonin-containing T-complex#GO:0005832;intracellular#GO:0005622 chaperonin#PC00073 HUMAN|HGNC=11022|UniProtKB=P78381 P78381 SLC35A2 PTHR10231:SF95 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-GALACTOSE TRANSLOCATOR inorganic molecular entity transmembrane transporter activity#GO:0015318;carbohydrate derivative transmembrane transporter activity#GO:1901505;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=16824|UniProtKB=P49019 P49019 HCAR3 PTHR46048:SF5 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 3 HUMAN|HGNC=4487|UniProtKB=O75388 O75388 GPR32 PTHR24225:SF27 CHEMOTACTIC RECEPTOR G-PROTEIN COUPLED RECEPTOR 32-RELATED signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;complement binding#GO:0001848;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;immune response-regulating signaling pathway#GO:0002764;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;activation of immune response#GO:0002253;divalent inorganic cation homeostasis#GO:0072507;regulation of lipase activity#GO:0060191;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;immune response-activating signal transduction#GO:0002757;activation of phospholipase C activity#GO:0007202;regulation of immune system process#GO:0002682;regulation of hydrolase activity#GO:0051336;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;cellular cation homeostasis#GO:0030003;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;regulation of immune response#GO:0050776;positive regulation of phospholipase activity#GO:0010518;positive regulation of immune system process#GO:0002684;homeostatic process#GO:0042592;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;metal ion homeostasis#GO:0055065 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=2256|UniProtKB=Q9UQ03 Q9UQ03 CORO2B PTHR10856:SF17 CORONIN CORONIN-2B cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 non-motor actin binding protein#PC00165 HUMAN|HGNC=346|UniProtKB=A9YTQ3 A9YTQ3 AHRR PTHR10649:SF3 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR REPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 HUMAN|Ensembl=ENSG00000284836|UniProtKB=A0A2R8YEV3 A0A2R8YEV3 OR2A42 PTHR26453:SF115 OLFACTORY RECEPTOR G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=49576|UniProtKB=A8MXQ7 A8MXQ7 IQANK1 PTHR24161:SF16 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED IQ MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1-RELATED transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=4012|UniProtKB=P19526 P19526 FUT1 PTHR11927:SF4 GALACTOSIDE 2-L-FUCOSYLTRANSFERASE GALACTOSIDE ALPHA-(1,2)-FUCOSYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 glycosyltransferase#PC00111 HUMAN|HGNC=27265|UniProtKB=P68543 P68543 UBXN2A PTHR23333:SF16 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 2A protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;membrane organization#GO:0061024;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;Golgi organization#GO:0007030;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;nuclear envelope organization#GO:0006998;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;autophagy#GO:0006914 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=7762|UniProtKB=Q13562 Q13562 NEUROD1 PTHR19290:SF88 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=25890|UniProtKB=Q86YD3 Q86YD3 TMEM25 PTHR47224:SF1 TRANSMEMBRANE PROTEIN 25 TRANSMEMBRANE PROTEIN 25 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;chemical synaptic transmission, postsynaptic#GO:0099565;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of system process#GO:0044057;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501 HUMAN|HGNC=11760|UniProtKB=P10646 P10646 TFPI PTHR10083:SF328 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED TISSUE FACTOR PATHWAY INHIBITOR serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>TFPI#P00417 HUMAN|HGNC=26988|UniProtKB=Q86XA0 Q86XA0 METTL23 PTHR14614:SF2 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN METHYLTRANSFERASE-LIKE PROTEIN 23 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26745|UniProtKB=Q8N8C0 Q8N8C0 ZNF781 PTHR14947:SF19 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 781 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28927|UniProtKB=Q3SY84 Q3SY84 KRT71 PTHR45616:SF16 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 71 HUMAN|HGNC=9413|UniProtKB=P78527 P78527 PRKDC PTHR11139:SF68 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;chromosome organization#GO:0051276;organelle organization#GO:0006996;biological regulation#GO:0065007;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=34211|UniProtKB=A8MX34 A8MX34 KRTAP29-1 PTHR23262:SF91 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 29-1 HUMAN|HGNC=33844|UniProtKB=Q49A17 Q49A17 GALNTL6 PTHR11675:SF23 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE-LIKE 6 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=11226|UniProtKB=Q96JI7 Q96JI7 SPG11 PTHR13650:SF0 UNCHARACTERIZED SPATACSIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2213|UniProtKB=P12111 P12111 COL6A3 PTHR24020:SF13 COLLAGEN ALPHA COLLAGEN ALPHA-3(VI) CHAIN extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=5331|UniProtKB=Q9HC29 Q9HC29 NOD2 PTHR24106:SF64 NACHT, LRR AND CARD DOMAINS-CONTAINING NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;response to bacterium#GO:0009617;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;defense response to bacterium#GO:0042742;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15702|UniProtKB=Q8WUA2 Q8WUA2 PPIL4 PTHR45843:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;phosphorylation of RNA polymerase II C-terminal domain#GO:0070816;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=3221|UniProtKB=P20827 P20827 EFNA1 PTHR11304:SF19 EPHRIN EPHRIN-A1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 anchored component of plasma membrane#GO:0046658;intrinsic component of membrane#GO:0031224;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;anchored component of membrane#GO:0031225;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=43972|UniProtKB=A0A3B3IT33 A0A3B3IT33 TRIM51GP PTHR24103:SF649 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING 51G, PSEUDOGENE ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=33787|UniProtKB=Q5JPI9 Q5JPI9 EEF1AKMT2 PTHR12843:SF5 PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10 EEF1A LYSINE METHYLTRANSFERASE 2 protein modifying enzyme#PC00260 HUMAN|HGNC=39025|UniProtKB=Q9QC07 Q9QC07 ERVK-18 PTHR41694:SF4 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 10 POL PROTEIN-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 viral or transposable element protein#PC00237 HUMAN|HGNC=15750|UniProtKB=P60981 P60981 DSTN PTHR11913:SF18 COFILIN-RELATED DESTRIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 protein-containing complex disassembly#GO:0032984;cellular protein complex disassembly#GO:0043624;actin polymerization or depolymerization#GO:0008154;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;locomotion#GO:0040011;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;actin cortical patch#GO:0030479;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=13111|UniProtKB=Q02386 Q02386 ZNF45 PTHR24377:SF830 IP01015P-RELATED ZINC FINGER PROTEIN 45 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25452|UniProtKB=Q8N4L2 Q8N4L2 PIP4P2 PTHR21014:SF5 UNCHARACTERIZED TYPE 2 PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 4-PHOSPHATASE HUMAN|HGNC=16772|UniProtKB=Q07627 Q07627 KRTAP1-1 PTHR23262:SF145 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 1-1 HUMAN|HGNC=26167|UniProtKB=Q86UB9 Q86UB9 TMEM135 PTHR12459:SF3 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 135 HUMAN|HGNC=18664|UniProtKB=Q92520 Q92520 FAM3C PTHR14592:SF10 UNCHARACTERIZED FAM3 PROTEIN FAM3C extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=34513|UniProtKB=A6NHJ4 A6NHJ4 ZNF860 PTHR24377:SF409 IP01015P-RELATED ZINC FINGER PROTEIN 860 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=3696|UniProtKB=Q14314 Q14314 FGL2 PTHR19143:SF189 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBROLEUKIN extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=547|UniProtKB=O76027 O76027 ANXA9 PTHR10502:SF122 ANNEXIN ANNEXIN A9 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calcium-binding protein#PC00060 HUMAN|HGNC=21746|UniProtKB=Q8NE35 Q8NE35 CPEB3 PTHR12566:SF7 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 synapse#GO:0045202;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=235|UniProtKB=Q8NFM4 Q8NFM4 ADCY4 PTHR45627:SF10 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 4 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 HUMAN|HGNC=410|UniProtKB=P43353 P43353 ALDH3B1 PTHR43570:SF2 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER B1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=4242|UniProtKB=O94808 O94808 GFPT2 PTHR10937:SF10 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 2 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;cellular aromatic compound metabolic process#GO:0006725;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;UDP-N-acetylglucosamine metabolic process#GO:0006047;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;protein N-linked glycosylation#GO:0006487;amino sugar metabolic process#GO:0006040;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 transaminase#PC00216 O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051;N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042 HUMAN|HGNC=4978|UniProtKB=Q14774 Q14774 HLX PTHR46808:SF1 H2.0-LIKE HOMEOBOX PROTEIN H2.0-LIKE HOMEOBOX PROTEIN homeodomain transcription factor#PC00119 HUMAN|HGNC=7553|UniProtKB=P01106 P01106 MYC PTHR45851:SF1 MYC PROTO-ONCOGENE MYC PROTO-ONCOGENE PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 CCKR signaling map#P06959>MYC#G07272;p53 pathway feedback loops 2#P04398>Myc#P04649;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Interleukin signaling pathway#P00036>c-Myc#P00995;Oxidative stress response#P00046>Myc#P01124;CCKR signaling map#P06959>MYC#G06979;PDGF signaling pathway#P00047>c-Myc#P01172 HUMAN|HGNC=7427|UniProtKB=P00156 P00156 MT-CYB PTHR19271:SF16 CYTOCHROME B CYTOCHROME B intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;membrane#GO:0016020 FAS signaling pathway#P00020>CytochromeC#P00620;Huntington disease#P00029>Cytochrome c#P00785 HUMAN|HGNC=13869|UniProtKB=P58215 P58215 LOXL3 PTHR45817:SF2 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 3 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175 HUMAN|HGNC=19405|UniProtKB=Q8N414 Q8N414 PGBD5 PTHR28576:SF2 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5 catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;transposition#GO:0032196;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 HUMAN|HGNC=6679|UniProtKB=Q93052 Q93052 LPP PTHR24207:SF0 ZYX102 PROTEIN LIPOMA-PREFERRED PARTNER cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856 kinase modulator#PC00140 HUMAN|HGNC=10591|UniProtKB=P35499 P35499 SCN4A PTHR10037:SF223 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 4 SUBUNIT ALPHA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sodium channel activity#GO:0005272;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;sodium ion transport#GO:0006814;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=24525|UniProtKB=Q9Y4U1 Q9Y4U1 MMACHC PTHR31457:SF2 METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE C PROTEIN CYANOCOBALAMIN REDUCTASE / ALKYLCOBALAMIN DEALKYLASE nucleotide binding#GO:0000166;demethylase activity#GO:0032451;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=11655|UniProtKB=P17987 P17987 TCP1 PTHR11353:SF192 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;chaperone complex#GO:0101031;cellular anatomical entity#GO:0110165;chaperonin-containing T-complex#GO:0005832;intracellular#GO:0005622 chaperonin#PC00073 HUMAN|HGNC=10448|UniProtKB=Q9P2E9 Q9P2E9 RRBP1 PTHR18939:SF6 RIBOSOME BINDING PROTEIN-1 RIBOSOME-BINDING PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9215|UniProtKB=P20265 P20265 POU3F2 PTHR11636:SF115 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=21657|UniProtKB=Q86SG5 Q86SG5 S100A7A PTHR11639:SF67 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A7A extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 calmodulin-related#PC00061 HUMAN|HGNC=28506|UniProtKB=Q8TBY9 Q8TBY9 CFAP251 PTHR13720:SF13 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 251 motile cilium#GO:0031514;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=28522|UniProtKB=Q8N6D2 Q8N6D2 RNF182 PTHR46675:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF182 E3 UBIQUITIN-PROTEIN LIGASE RNF182 HUMAN|HGNC=15162|UniProtKB=Q8NH83 Q8NH83 OR4A5 PTHR48002:SF161 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4A5-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=28508|UniProtKB=Q8NE22 Q8NE22 SETD9 PTHR33524:SF2 C5ORF35 SET DOMAIN-CONTAINING PROTEIN 9 HUMAN|HGNC=25901|UniProtKB=Q8N4X5 Q8N4X5 AFAP1L2 PTHR14338:SF4 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1-LIKE 2 protein binding#GO:0005515;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of cytokine production#GO:0001819;positive regulation of signaling#GO:0023056;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of multicellular organismal process#GO:0051239;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;cytokine production#GO:0001816;inflammatory response#GO:0006954;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;positive regulation of macromolecule biosynthetic process#GO:0010557;mitotic nuclear division#GO:0140014;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of mitotic cell cycle#GO:0007346;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=25118|UniProtKB=Q96BN8 Q96BN8 OTULIN PTHR33662:SF2 OTU DEUBIQUITINASE WITH LINEAR LINKAGE-SPECIFICITY A-RELATED UBIQUITIN THIOESTERASE OTULIN thiol-dependent ubiquitin-specific protease activity#GO:0004843;hydrolase activity#GO:0016787;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=17004|UniProtKB=Q9H0M0 Q9H0M0 WWP1 PTHR11254:SF299 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE E3 UBIQUITIN-PROTEIN LIGASE WWP1 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 HUMAN|HGNC=19997|UniProtKB=Q7Z602 Q7Z602 GPR141 PTHR24237:SF35 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 141-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=23781|UniProtKB=Q9Y2S7 Q9Y2S7 POLDIP2 PTHR14289:SF16 F-BOX ONLY PROTEIN 3 POLYMERASE DELTA-INTERACTING PROTEIN 2 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 HUMAN|HGNC=22235|UniProtKB=Q8NC69 Q8NC69 KCTD6 PTHR14499:SF10 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD6 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25676|UniProtKB=Q5T7V8 Q5T7V8 GORAB PTHR21470:SF2 RAB6-INTERACTING PROTEIN GORAB RAB6-INTERACTING GOLGIN HUMAN|HGNC=27622|UniProtKB=Q6ZNA5 Q6ZNA5 FRRS1 PTHR45828:SF3 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE FERRIC-CHELATE REDUCTASE 1 reductase#PC00198 HUMAN|HGNC=32397|UniProtKB=Q8WWF6 Q8WWF6 DNAJB3 PTHR43948:SF1 FAMILY NOT NAMED DNAJ HOMOLOG SUBFAMILY B MEMBER 3 HUMAN|HGNC=10431|UniProtKB=Q15349 Q15349 RPS6KA2 PTHR24351:SF213 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 Ras Pathway#P04393>p90RSK#P04541;Interleukin signaling pathway#P00036>p90RSK#P00964;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 HUMAN|HGNC=26332|UniProtKB=Q569K4 Q569K4 ZNF385B PTHR23067:SF8 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385B membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=25205|UniProtKB=Q8WVF2 Q8WVF2 UCMA PTHR28647:SF2 UNIQUE CARTILAGE MATRIX-ASSOCIATED PROTEIN UNIQUE CARTILAGE MATRIX-ASSOCIATED PROTEIN chordate embryonic development#GO:0043009;system development#GO:0048731;embryo development#GO:0009790;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;embryo development ending in birth or egg hatching#GO:0009792;multicellular organismal process#GO:0032501;skeletal system development#GO:0001501 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=325|UniProtKB=O15120 O15120 AGPAT2 PTHR10434:SF2 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE BETA transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=20606|UniProtKB=Q13099 Q13099 IFT88 PTHR44117:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 vesicle targeting, to, from or within Golgi#GO:0048199;non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;ciliary base#GO:0097546;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular non-membrane-bounded organelle#GO:0043232;ciliary transition fiber#GO:0097539;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=6774|UniProtKB=O15198 O15198 SMAD9 PTHR13703:SF41 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 9 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;ubiquitin protein ligase binding#GO:0031625;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;nucleobase-containing compound metabolic process#GO:0006139;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;response to BMP#GO:0071772;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;BMP signaling pathway#GO:0030509;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;response to growth factor#GO:0070848;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to growth factor stimulus#GO:0071363;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 HUMAN|HGNC=6491|UniProtKB=A4D0S4 A4D0S4 LAMB4 PTHR10574:SF279 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-4 integrin binding#GO:0005178;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cell morphogenesis involved in differentiation#GO:0000904;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;substrate adhesion-dependent cell spreading#GO:0034446;localization of cell#GO:0051674;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;extracellular matrix organization#GO:0030198;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;cell differentiation#GO:0030154;extracellular structure organization#GO:0043062;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;cell migration#GO:0016477;locomotion#GO:0040011 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=17973|UniProtKB=Q9P109 Q9P109 GCNT4 PTHR19297:SF7 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 4 glycosyltransferase#PC00111 HUMAN|HGNC=13206|UniProtKB=O60296 O60296 TRAK2 PTHR15751:SF13 TRAFFICKING KINESIN-BINDING PROTEIN TRAFFICKING KINESIN-BINDING PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;signaling receptor binding#GO:0005102;binding#GO:0005488 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;neurogenesis#GO:0022008;organelle localization#GO:0051640;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;nervous system development#GO:0007399;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;system development#GO:0048731;cell differentiation#GO:0030154;axo-dendritic transport#GO:0008088;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;mitochondrion organization#GO:0007005;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;protein targeting#GO:0006605;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;transport along microtubule#GO:0010970;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitochondrion distribution#GO:0048311;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;dendrite#GO:0030425;cell periphery#GO:0071944;mitochondrion#GO:0005739;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=12479|UniProtKB=Q969T4 Q969T4 UBE2E3 PTHR24068:SF63 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E3 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=19306|UniProtKB=Q8NEW0 Q8NEW0 SLC30A7 PTHR45755:SF4 FAMILY NOT NAMED ZINC TRANSPORTER 7 HUMAN|HGNC=6772|UniProtKB=O43541 O43541 SMAD6 PTHR13703:SF28 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 6 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;ubiquitin protein ligase binding#GO:0031625;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;nucleobase-containing compound metabolic process#GO:0006139;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;response to BMP#GO:0071772;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;BMP signaling pathway#GO:0030509;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;response to growth factor#GO:0070848;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to growth factor stimulus#GO:0071363;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 TGF-beta signaling pathway#P00052>I-SMAD#G01548;TGF-beta signaling pathway#P00052>I-Smads#P01289 HUMAN|HGNC=29040|UniProtKB=Q5T011 Q5T011 SZT2 PTHR14918:SF3 KICSTOR COMPLEX PROTEIN SZT2 KICSTOR COMPLEX PROTEIN SZT2 HUMAN|HGNC=8878|UniProtKB=Q01813 Q01813 PFKP PTHR13697:SF5 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, PLATELET TYPE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;carbon-carbon lyase activity#GO:0016830;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;fructose-bisphosphate aldolase activity#GO:0004332;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;carbohydrate binding#GO:0030246;isomerase activity#GO:0016853;kinase activity#GO:0016301;oxidoreductase activity#GO:0016491;cation binding#GO:0043169;carbon-oxygen lyase activity#GO:0016835;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;hydro-lyase activity#GO:0016836;intramolecular transferase activity#GO:0016866;organic cyclic compound binding#GO:0097159;identical protein binding#GO:0042802;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glucose metabolic process#GO:0006006;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;hexose metabolic process#GO:0019318;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695 carbohydrate kinase#PC00065 HUMAN|HGNC=33783|UniProtKB=A6NFD8 A6NFD8 HELT PTHR10985:SF8 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY AND ENHANCER OF SPLIT-RELATED PROTEIN HELT cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 HUMAN|HGNC=651|UniProtKB=P15514 P15514 AREG PTHR10740:SF12 TRANSFORMING GROWTH FACTOR ALPHA AMPHIREGULIN regulation of protein modification process#GO:0031399;regulation of mitotic nuclear division#GO:0007088;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of organelle organization#GO:0033043;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell cycle process#GO:0090068;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of mitotic cell cycle#GO:0007346 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 HUMAN|HGNC=12490|UniProtKB=O14933 O14933 UBE2L6 PTHR24068:SF43 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN/ISG15-CONJUGATING ENZYME E2 L6 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>UbcH8#P01223;Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=823|UniProtKB=P25705 P25705 ATP5F1A PTHR48082:SF3 ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524;ATPase activity#GO:0016887 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide biosynthetic process#GO:0009152 ATP synthase#PC00002 ATP synthesis#P02721>F1 alpha#P02791 HUMAN|HGNC=20076|UniProtKB=Q96K76 Q96K76 USP47 PTHR24006:SF702 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 47 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=12791|UniProtKB=Q14191 Q14191 WRN PTHR13710:SF120 DNA HELICASE RECQ FAMILY MEMBER WERNER SYNDROME ATP-DEPENDENT HELICASE pyrophosphatase activity#GO:0016462;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA helicase#PC00011 p53 pathway#P00059>WRN#P04617 HUMAN|HGNC=24880|UniProtKB=O95274 O95274 LYPD3 PTHR10624:SF8 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR-RELATED LY6/PLAUR DOMAIN-CONTAINING PROTEIN 3 extracellular matrix binding#GO:0050840;protein binding#GO:0005515;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=1848|UniProtKB=P19835 P19835 CEL PTHR43903:SF1 NEUROLIGIN BILE SALT-ACTIVATED LIPASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;signaling receptor activity#GO:0038023;lipase activity#GO:0016298;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;triglyceride lipase activity#GO:0004806 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;transport#GO:0006810;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;vesicle organization#GO:0016050;cell junction assembly#GO:0034329;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;endocytosis#GO:0006897;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;vesicle budding from membrane#GO:0006900;synapse assembly#GO:0007416;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;vesicle-mediated transport in synapse#GO:0099003 cell surface#GO:0009986;synapse#GO:0045202;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;cell junction#GO:0030054;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=11507|UniProtKB=Q16563 Q16563 SYPL1 PTHR10306:SF9 SYNAPTOPHYSIN SYNAPTOPHYSIN-LIKE PROTEIN 1 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;syntaxin-1 binding#GO:0017075 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptophysin#P05777 HUMAN|HGNC=20626|UniProtKB=Q9P2D1 Q9P2D1 CHD7 PTHR45623:SF20 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7 HUMAN|HGNC=18644|UniProtKB=Q9P2G9 Q9P2G9 KLHL8 PTHR24412:SF471 KELCH PROTEIN KELCH-LIKE PROTEIN 8 scaffold/adaptor protein#PC00226 HUMAN|HGNC=14962|UniProtKB=Q7L8C5 Q7L8C5 SYT13 PTHR10024:SF250 SYNAPTOTAGMIN SYNAPTOTAGMIN-13 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;syntaxin binding#GO:0019905;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;synaptic signaling#GO:0099536;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;neurotransmitter secretion#GO:0007269;response to inorganic substance#GO:0010035;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;exocytic process#GO:0140029;cellular component organization or biogenesis#GO:0071840;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;regulation of neurotransmitter levels#GO:0001505;regulation of ion transport#GO:0043269;export from cell#GO:0140352;vesicle fusion#GO:0006906;regulation of signaling#GO:0023051;transport#GO:0006810;cation transport#GO:0006812;organic substance transport#GO:0071702;regulation of transport#GO:0051049;neurotransmitter transport#GO:0006836;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;response to metal ion#GO:0010038;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;response to chemical#GO:0042221;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=14103|UniProtKB=O15013 O15013 ARHGEF10 PTHR12877:SF14 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 10 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;contractile actin filament bundle assembly#GO:0030038;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;mitotic spindle assembly#GO:0090307;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;regulation of actin filament-based process#GO:0032970;spindle organization#GO:0007051;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;cellular component assembly#GO:0022607;stress fiber assembly#GO:0043149;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;positive regulation of cytoskeleton organization#GO:0051495;organelle fission#GO:0048285;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=9755|UniProtKB=Q15274 Q15274 QPRT PTHR32179:SF3 NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;organophosphate biosynthetic process#GO:0090407;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=31981|UniProtKB=Q5VUR7 Q5VUR7 ANKRD20A3P PTHR24147:SF1 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 20A1-RELATED HUMAN|HGNC=15813|UniProtKB=Q9BZA8 Q9BZA8 PCDH11Y PTHR24028:SF254 CADHERIN-87A PROTOCADHERIN-11 X-LINKED-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=16815|UniProtKB=Q8TCT1 Q8TCT1 PHOSPHO1 PTHR20889:SF2 PHOSPHATASE, ORPHAN 1, 2 PHOSPHOETHANOLAMINE/PHOSPHOCHOLINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181 HUMAN|HGNC=4938|UniProtKB=P20036 P20036 HLA-DPA1 PTHR19944:SF64 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DP ALPHA 1 CHAIN major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 HUMAN|HGNC=25600|UniProtKB=Q9NV64 Q9NV64 TMEM39A PTHR12995:SF3 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 39A negative regulation of cellular metabolic process#GO:0031324;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;regulation of cellular component organization#GO:0051128;regulation of autophagosome assembly#GO:2000785;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;negative regulation of organelle organization#GO:0010639;proteolysis#GO:0006508;catabolic process#GO:0009056;autophagosome maturation#GO:0097352;negative regulation of cellular component organization#GO:0051129;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;regulation of macroautophagy#GO:0016241;cellular component organization#GO:0016043;regulation of cellular catabolic process#GO:0031329;negative regulation of autophagy#GO:0010507;cellular process#GO:0009987;negative regulation of macroautophagy#GO:0016242;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;negative regulation of catabolic process#GO:0009895;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;regulation of autophagosome maturation#GO:1901096;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=28210|UniProtKB=Q86UY5 Q86UY5 FAM83A PTHR16181:SF20 UNCHARACTERIZED PROTEIN FAM83A regulation of biological process#GO:0050789;response to stimulus#GO:0050896;epidermal growth factor receptor signaling pathway#GO:0007173;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;ERBB signaling pathway#GO:0038127;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 HUMAN|HGNC=33293|UniProtKB=P0C2W7 P0C2W7 CT47B1 PTHR32157:SF5 GENE 6268-RELATED CANCER/TESTIS ANTIGEN 47B HUMAN|HGNC=18609|UniProtKB=Q8NA42 Q8NA42 ZNF383 PTHR24390:SF187 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 383 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=19943|UniProtKB=Q9Y296 Q9Y296 TRAPPC4 PTHR23249:SF15 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008 membrane traffic protein#PC00150 HUMAN|HGNC=3477|UniProtKB=P62495 P62495 ETF1 PTHR10113:SF21 PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular protein complex disassembly#GO:0043624;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;translational termination#GO:0006415;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 translation release factor#PC00225 HUMAN|HGNC=16305|UniProtKB=Q8TE58 Q8TE58 ADAMTS15 PTHR13723:SF39 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 15 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=26933|UniProtKB=Q5T280 Q5T280 SPOUT1 PTHR12150:SF13 CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED METHYLTRANSFERASE C9ORF114-RELATED methyltransferase#PC00155 HUMAN|HGNC=12405|UniProtKB=P02766 P02766 TTR PTHR10395:SF12 URICASE AND TRANSTHYRETIN-RELATED TRANSTHYRETIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 hydrolase#PC00121 HUMAN|HGNC=17617|UniProtKB=Q96LA9 Q96LA9 MRGPRX4 PTHR11334:SF59 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MEMBER X4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=17304|UniProtKB=O75529 O75529 TAF5L PTHR19879:SF6 TRANSCRIPTION INITIATION FACTOR TFIID TAF5-LIKE RNA POLYMERASE II P300/CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 5L molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110;RNA polymerase II general transcription initiation factor activity#GO:0016251 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;histone H3 acetylation#GO:0043966;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;histone acetylation#GO:0016573;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;RNA polymerase II, holoenzyme#GO:0016591;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;chromosome#GO:0005694;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=21614|UniProtKB=Q9GZU7 Q9GZU7 CTDSP1 PTHR12210:SF139 NUCLEAR LIM INTERACTOR-INTERACTING FACTOR-RELATED CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 HUMAN|HGNC=21231|UniProtKB=Q5SW24 Q5SW24 DACT2 PTHR15919:SF13 DAPPER-RELATED DAPPER HOMOLOG 2 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;Wnt signaling pathway#GO:0016055;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of canonical Wnt signaling pathway#GO:0060828;activin receptor signaling pathway#GO:0032924;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of Wnt signaling pathway#GO:0030111;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=11068|UniProtKB=P32418 P32418 SLC8A1 PTHR11878:SF6 SODIUM/CALCIUM EXCHANGER SODIUM/CALCIUM EXCHANGER 1 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;cation:cation antiporter activity#GO:0015491;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;solute:cation antiporter activity#GO:0015298;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;sodium ion transport#GO:0006814;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725 synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;sarcolemma#GO:0042383;axon#GO:0030424;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=4236|UniProtKB=P55789 P55789 GFER PTHR12645:SF0 ALR/ERV FAD-LINKED SULFHYDRYL OXIDASE ALR nucleotide binding#GO:0000166;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidase#PC00175 HUMAN|HGNC=13099|UniProtKB=P13682 P13682 ZNF35 PTHR24381:SF60 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 35 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21219|UniProtKB=Q9UPZ9 Q9UPZ9 CILK1 PTHR24055:SF260 MITOGEN-ACTIVATED PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE ICK transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;establishment of organelle localization#GO:0051656;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;macromolecule metabolic process#GO:0043170;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;regulation of metabolic process#GO:0019222;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;signal transduction#GO:0007165;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;vesicle localization#GO:0051648;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;response to stimulus#GO:0050896;microtubule-based transport#GO:0099111;regulation of macromolecule metabolic process#GO:0060255;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=1952|UniProtKB=P20309 P20309 CHRM3 PTHR24247:SF183 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M3 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;organic cyclic compound binding#GO:0097159;acetylcholine receptor activity#GO:0015464;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;acetylcholine binding#GO:0042166;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 blood circulation#GO:0008015;regulation of adenylate cyclase activity#GO:0045761;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of muscle contraction#GO:0006937;negative regulation of intracellular signal transduction#GO:1902532;regulation of cyclase activity#GO:0031279;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of blood vessel diameter#GO:0097746;regulation of system process#GO:0044057;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of anatomical structure size#GO:0090066;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;negative regulation of response to stimulus#GO:0048585;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;smooth muscle contraction#GO:0006939;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of catalytic activity#GO:0043086;cAMP-mediated signaling#GO:0019933;muscle system process#GO:0003012;cyclic-nucleotide-mediated signaling#GO:0019935;muscle contraction#GO:0006936;negative regulation of molecular function#GO:0044092 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>mAChR1/3#P01069;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=5414|UniProtKB=Q01628 Q01628 IFITM3 PTHR13999:SF4 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 3 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to cytokine#GO:0034097;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;innate immune response#GO:0045087;defense response to virus#GO:0051607;cytokine-mediated signaling pathway#GO:0019221;defense response#GO:0006952;signaling#GO:0023052;immune effector process#GO:0002252;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;cell communication#GO:0007154;cellular process#GO:0009987;response to type I interferon#GO:0034340;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;type I interferon signaling pathway#GO:0060337 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=387|UniProtKB=P17516 P17516 AKR1C4 PTHR11732:SF165 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER C4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=29923|UniProtKB=Q9H1E3 Q9H1E3 NUCKS1 PTHR15361:SF1 RAD51/NUKS-INTERACTING PROTEIN NUCLEAR UBIQUITOUS CASEIN AND CYCLIN-DEPENDENT KINASE SUBSTRATE 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=4205|UniProtKB=O95395 O95395 GCNT3 PTHR19297:SF81 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 3 glycosyltransferase#PC00111 HUMAN|HGNC=13507|UniProtKB=Q96PQ6 Q96PQ6 ZNF317 PTHR24377:SF22 IP01015P-RELATED ZINC FINGER PROTEIN 317 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18071|UniProtKB=Q7Z589 Q7Z589 EMSY PTHR16500:SF3 BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=6730|UniProtKB=Q9HBG7 Q9HBG7 LY9 PTHR12080:SF44 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE T-LYMPHOCYTE SURFACE ANTIGEN LY-9 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=5620|UniProtKB=P01780 P01780 IGHV3-7 PTHR23266:SF223 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-7 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=9783|UniProtKB=P20339 P20339 RAB5A PTHR24073:SF1129 DRAB5-RELATED RAS-RELATED PROTEIN RAB-5A pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular component biogenesis#GO:0044087;synaptic signaling#GO:0099536;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;regulation of endocytosis#GO:0030100;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;cell projection assembly#GO:0030031;regulation of synaptic plasticity#GO:0048167;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell projection assembly#GO:0060491;protein transport#GO:0015031;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031 synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=11449|UniProtKB=P53597 P53597 SUCLG1 PTHR11117:SF2 SUCCINYL-COA LIGASE SUBUNIT ALPHA SUCCINATE--COA LIGASE [ADP/GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 ligase#PC00142 TCA cycle#P00051>Succinyl CoA Synthetase#P01274 HUMAN|HGNC=17922|UniProtKB=Q9BWE0 Q9BWE0 REPIN1 PTHR24406:SF10 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED REPLICATION INITIATOR 1 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=17904|UniProtKB=Q9NRR4 Q9NRR4 DROSHA PTHR11207:SF0 RIBONUCLEASE III RIBONUCLEASE 3 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;double-stranded RNA binding#GO:0003725 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 endoribonuclease#PC00094 HUMAN|HGNC=1944|UniProtKB=P52757 P52757 CHN2 PTHR46075:SF4 CHIMERIN FAMILY MEMBER BETA-CHIMAERIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 HUMAN|HGNC=3439|UniProtKB=Q13216 Q13216 ERCC8 PTHR46202:SF1 DNA EXCISION REPAIR PROTEIN ERCC-8 DNA EXCISION REPAIR PROTEIN ERCC-8 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;nucleotide-excision repair#GO:0006289;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of DNA repair#GO:0045739;macromolecule modification#GO:0043412;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of DNA repair#GO:0006282;positive regulation of response to stimulus#GO:0048584;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;nucleotide-excision repair complex#GO:0000109;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 DNA metabolism protein#PC00009 HUMAN|HGNC=8111|UniProtKB=Q8TAX0 Q8TAX0 OSR1 PTHR14196:SF5 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED-RELATED 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;urogenital system development#GO:0001655;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=2484|UniProtKB=P33240 P33240 CSTF2 PTHR45735:SF6 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=17260|UniProtKB=O95379 O95379 TNFAIP8 PTHR12757:SF3 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Huntington disease#P00029>FIP-2#P00772 HUMAN|HGNC=8583|UniProtKB=P05121 P05121 SERPINE1 PTHR11461:SF49 SERINE PROTEASE INHIBITOR, SERPIN PLASMINOGEN ACTIVATOR INHIBITOR 1 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 CCKR signaling map#P06959>PAI1#G07281;Plasminogen activating cascade#P00050>PAI-1#P01245;Blood coagulation#P00011>PAI-1#P00411;CCKR signaling map#P06959>PAI1#G06987;p53 pathway#P00059>PAI#G04700 HUMAN|HGNC=17993|UniProtKB=Q8TD43 Q8TD43 TRPM4 PTHR13800:SF6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 4 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;localization#GO:0051179;divalent metal ion transport#GO:0070838;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=15161|UniProtKB=Q8NGN8 Q8NGN8 OR4A4P PTHR48002:SF121 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4A4-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=19066|UniProtKB=Q9Y330 Q9Y330 ZBTB12 PTHR24399:SF38 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 12 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7526|UniProtKB=P22033 P22033 MMUT PTHR48101:SF4 METHYLMALONYL-COA MUTASE, MITOCHONDRIAL-RELATED METHYLMALONYL-COA MUTASE, MITOCHONDRIAL isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 mutase#PC00160 Methylmalonyl pathway#P02755>Methylmalonyl-CoA mutase#P03034;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA mutase#P03161 HUMAN|HGNC=26532|UniProtKB=Q96M86 Q96M86 DNHD1 PTHR10676:SF359 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN DOMAIN-CONTAINING PROTEIN 1 pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement#GO:0003341 supramolecular complex#GO:0099080;axoneme#GO:0005930;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 HUMAN|HGNC=963|UniProtKB=Q9UIF8 Q9UIF8 BAZ2B PTHR45915:SF1 TRANSCRIPTION INTERMEDIARY FACTOR BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=15858|UniProtKB=Q9NVP4 Q9NVP4 DZANK1 PTHR16058:SF4 DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 HUMAN|HGNC=12484|UniProtKB=P62256 P62256 UBE2H PTHR24068:SF128 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 H ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=13203|UniProtKB=Q9GZX7 Q9GZX7 AICDA PTHR13857:SF10 MRNA EDITING ENZYME SINGLE-STRANDED DNA CYTOSINE DEAMINASE RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363 response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;RNA phosphodiester bond hydrolysis#GO:0090501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;defense response to virus#GO:0051607;demethylation#GO:0070988;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;transposition#GO:0032196;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;RNA-dependent DNA biosynthetic process#GO:0006278;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;nucleic acid phosphodiester bond hydrolysis#GO:0090305;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147 HUMAN|HGNC=29608|UniProtKB=Q86UE4 Q86UE4 MTDH PTHR23251:SF0 LYSINE-RICH CEACAM1 CO-ISOLATED PROTEIN LYRIC PROTEIN PROTEIN LYRIC HUMAN|HGNC=27393|UniProtKB=Q5TGY1 Q5TGY1 TMCO4 PTHR17920:SF3 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=26600|UniProtKB=Q562E7 Q562E7 WDR81 PTHR44662:SF1 WD REPEAT-CONTAINING PROTEIN 81 WD REPEAT-CONTAINING PROTEIN 81 HUMAN|HGNC=4099|UniProtKB=Q6NT46 Q6NT46 GAGE2A PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=13502|UniProtKB=Q9HBT7 Q9HBT7 ZNF287 PTHR23226:SF194 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 287 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26266|UniProtKB=Q6P1R3 Q6P1R3 MSANTD2 PTHR46933:SF1 MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 2 MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=32237|UniProtKB=A6NH21 A6NH21 SERINC4 PTHR10383:SF5 SERINE INCORPORATOR SERINE INCORPORATOR 4 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 HUMAN|HGNC=14874|UniProtKB=Q96PH1 Q96PH1 NOX5 PTHR11972:SF58 NADPH OXIDASE NADPH OXIDASE 5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;oxidoreductase complex#GO:1990204;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175 HUMAN|HGNC=14742|UniProtKB=Q8NGD1 Q8NGD1 OR4N2 PTHR48002:SF120 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4N2 transmembrane signal receptor#PC00197 HUMAN|HGNC=22800|UniProtKB=A8MTJ3 A8MTJ3 GNAT3 PTHR10218:SF66 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-3 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;detection of chemical stimulus#GO:0009593;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 9+0 non-motile cilium#GO:0097731;membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;non-motile cilium#GO:0097730;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;cytoplasmic side of plasma membrane#GO:0009898;intraciliary transport particle#GO:0030990;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 HUMAN|HGNC=4116|UniProtKB=Q14376 Q14376 GALE PTHR43725:SF8 UDP-GLUCOSE 4-EPIMERASE UDP-GLUCOSE 4-EPIMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;small molecule catabolic process#GO:0044282;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 epimerase/racemase#PC00096 O-antigen biosynthesis#P02757>dTDP-glucose 4,6-dehydratase#P03045;Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965 HUMAN|HGNC=10250|UniProtKB=Q9HCK4 Q9HCK4 ROBO2 PTHR44170:SF9 PROTEIN SIDEKICK ROUNDABOUT HOMOLOG 2 HUMAN|HGNC=9866|UniProtKB=P13631 P13631 RARG PTHR24082:SF116 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=30972|UniProtKB=Q96T21 Q96T21 SECISBP2 PTHR13284:SF9 GH01354P SELENOCYSTEINE INSERTION SEQUENCE-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;mRNA 3'-UTR binding#GO:0003730 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 HUMAN|HGNC=26063|UniProtKB=Q9NWU1 Q9NWU1 OXSM PTHR11712:SF297 POLYKETIDE SYNTHASE-RELATED 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=721|UniProtKB=P54793 P54793 ARSF PTHR42693:SF2 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE F hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=1461|UniProtKB=Q13554 Q13554 CAMK2B PTHR24347:SF403 SERINE/THREONINE-PROTEIN KINASE CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT BETA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Gonadotropin-releasing hormone receptor pathway#P06664>Ca/CaMK II#P06735;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 HUMAN|HGNC=40020|UniProtKB=E7ERA6 E7ERA6 RNF223 PTHR22791:SF4 UNCHARACTERIZED RING FINGER PROTEIN 223 HUMAN|HGNC=2718|UniProtKB=Q92466 Q92466 DDB2 PTHR15169:SF0 DAMAGE-SPECIFIC DNA BINDING PROTEIN 2 DNA DAMAGE-BINDING PROTEIN 2 damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;response to UV#GO:0009411;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 damaged DNA-binding protein#PC00086 p53 pathway#P00059>p48#G04705 HUMAN|HGNC=24087|UniProtKB=Q0VD83 Q0VD83 APOBR PTHR15964:SF0 APOLIPOPROTEIN B48 RECEPTOR APOLIPOPROTEIN B RECEPTOR HUMAN|HGNC=4862|UniProtKB=P55160 P55160 NCKAP1L PTHR12093:SF9 NCK-ASSOCIATED PROTEIN 1 NCK-ASSOCIATED PROTEIN 1-LIKE Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048 cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell projection assembly#GO:0030031;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699;cell migration#GO:0016477;locomotion#GO:0040011;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=2858|UniProtKB=Q16854 Q16854 DGUOK PTHR10513:SF8 DEOXYNUCLEOSIDE KINASE DEOXYGUANOSINE KINASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotide kinase#PC00172 HUMAN|HGNC=18333|UniProtKB=Q4W5G0 Q4W5G0 TIGD2 PTHR19303:SF22 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 HUMAN|HGNC=11245|UniProtKB=P20155 P20155 SPINK2 PTHR47608:SF1 SERINE PROTEASE INHIBITOR KAZAL-TYPE 2, SPINK2 SERINE PROTEASE INHIBITOR KAZAL-TYPE 2 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 protease inhibitor#PC00191 HUMAN|HGNC=19745|UniProtKB=Q9NQZ7 Q9NQZ7 ENTPD7 PTHR11782:SF37 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 7 nucleotide phosphatase#PC00173 HUMAN|HGNC=8694|UniProtKB=Q9Y5E1 Q9Y5E1 PCDHB9 PTHR24028:SF128 CADHERIN-87A PROTOCADHERIN BETA-9 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=4069|UniProtKB=Q9BY60 Q9BY60 GABARAPL3 PTHR10969:SF16 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 3 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;signaling receptor binding#GO:0005102;ubiquitin-like protein ligase binding#GO:0044389 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;whole membrane#GO:0098805 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=30002|UniProtKB=Q58WW2 Q58WW2 DCAF6 PTHR15574:SF39 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 6 transcription coactivator activity#GO:0003713;nuclear receptor transcription coactivator activity#GO:0030374;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=10617|UniProtKB=Q99731 Q99731 CCL19 PTHR12015:SF80 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 19 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=13797|UniProtKB=Q9BXM0 Q9BXM0 PRX PTHR23348:SF42 PERIAXIN/AHNAK PERIAXIN cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;membrane organization#GO:0061024;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;plasma membrane organization#GO:0007009;developmental process#GO:0032502;RNA processing#GO:0006396;endomembrane system organization#GO:0010256;gene expression#GO:0010467;gliogenesis#GO:0042063;peripheral nervous system development#GO:0007422;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;myelination#GO:0042552;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=20594|UniProtKB=Q9UHF1 Q9UHF1 EGFL7 PTHR14949:SF21 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 7 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 anatomical structure development#GO:0048856;developmental process#GO:0032502 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=2428|UniProtKB=P16989 P16989 YBX3 PTHR11544:SF14 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 3 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 Gonadotropin-releasing hormone receptor pathway#P06664>Csda#P06797 HUMAN|HGNC=33107|UniProtKB=Q6AW86 Q6AW86 ZNF324B PTHR24377:SF670 IP01015P-RELATED ZINC FINGER PROTEIN 324B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=20595|UniProtKB=Q5JR59 Q5JR59 MTUS2 PTHR24200:SF14 TOUCAN, ISOFORM A MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR CANDIDATE 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=2320|UniProtKB=Q9UBL6 Q9UBL6 CPNE7 PTHR10857:SF6 COPINE COPINE-7 calcium-dependent phospholipid binding#GO:0005544;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;binding#GO:0005488 response to metal ion#GO:0010038;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=34414|UniProtKB=Q6ZMU1 Q6ZMU1 C3P1 PTHR11412:SF111 MACROGLOBULIN / COMPLEMENT PROTEIN C3P1-RELATED protease inhibitor#PC00191 HUMAN|HGNC=24676|UniProtKB=Q14296 Q14296 FASTK PTHR21228:SF4 FAST LEU-RICH DOMAIN-CONTAINING FAS-ACTIVATED SERINE/THREONINE KINASE HUMAN|HGNC=16493|UniProtKB=Q9ULJ6 Q9ULJ6 ZMIZ1 PTHR10782:SF7 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;ubiquitin-like protein ligase activity#GO:0061659;RNA polymerase II transcription factor binding#GO:0001085;nuclear receptor transcription coactivator activity#GO:0030374;molecular function regulator#GO:0098772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;transcription factor binding#GO:0008134 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 HUMAN|HGNC=15494|UniProtKB=Q9H246 Q9H246 C1orf21 PTHR14974:SF3 SIMILAR TO RIKEN CDNA 1700025G04 GENE SIMILAR TO RIKEN CDNA 1700025G04 GENE HUMAN|HGNC=32017|UniProtKB=Q08AH3 Q08AH3 ACSM2A PTHR43605:SF14 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 HUMAN|HGNC=31009|UniProtKB=H0YL14 H0YL14 TMEM250 PTHR18884:SF108 SEPTIN TRANSMEMBRANE PROTEIN 250 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cell division#GO:0051301;cellular localization#GO:0051641;membrane fission#GO:0090148;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 HUMAN|HGNC=6707|UniProtKB=P33241 P33241 LSP1 PTHR18949:SF1 CALDESMON LYMPHOCYTE-SPECIFIC PROTEIN 1 non-motor actin binding protein#PC00165 HUMAN|HGNC=1718|UniProtKB=Q9UNH5 Q9UNH5 CDC14A PTHR23339:SF77 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14A phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;regulation of mitotic nuclear division#GO:0007088;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;regulation of exit from mitosis#GO:0007096;nuclear division#GO:0000280;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;axoneme assembly#GO:0035082;regulation of cell division#GO:0051302;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;positive regulation of biological process#GO:0048518;regulation of cytokinesis#GO:0032465;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;positive regulation of cytokinesis#GO:0032467;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;cell cycle phase transition#GO:0044770;intraciliary transport#GO:0042073;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;cell cycle arrest#GO:0007050;positive regulation of cell division#GO:0051781;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;cell division#GO:0051301;negative regulation of biological process#GO:0048519;mitotic cell cycle phase transition#GO:0044772;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle process#GO:1903047;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;positive regulation of cell cycle process#GO:0090068;cytoskeleton-dependent intracellular transport#GO:0030705;mitotic nuclear division#GO:0140014;protein localization to organelle#GO:0033365;negative regulation of cellular process#GO:0048523;cytokinesis#GO:0000910;membrane fission#GO:0090148;vesicle localization#GO:0051648;regulation of nuclear division#GO:0051783;negative regulation of mitotic cell cycle#GO:0045930;intraciliary transport involved in cilium assembly#GO:0035735;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;stereocilium#GO:0032420;non-membrane-bounded organelle#GO:0043228;kinocilium#GO:0060091;stereocilium bundle#GO:0032421;actin cytoskeleton#GO:0015629;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;membrane-enclosed lumen#GO:0031974;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;organelle lumen#GO:0043233;cluster of actin-based cell projections#GO:0098862;nucleus#GO:0005634;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;centriole#GO:0005814;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;neuron projection#GO:0043005;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;nuclear lumen#GO:0031981;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 protein phosphatase#PC00195 HUMAN|HGNC=8053|UniProtKB=P53370 P53370 NUDT6 PTHR13994:SF46 NUDIX HYDROLASE RELATED NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 6 pyrophosphatase activity#GO:0016462;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotide diphosphatase activity#GO:0004551;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 nucleotide phosphatase#PC00173 HUMAN|HGNC=20173|UniProtKB=Q8IXX5 Q8IXX5 TMEM183A PTHR20988:SF2 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 183A-RELATED HUMAN|HGNC=5232|UniProtKB=P0DMV8 P0DMV8 HSPA1A PTHR19375:SF223 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 1A-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524;ATPase activity#GO:0016887 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;chaperone-mediated protein folding#GO:0061077;cellular response to organic substance#GO:0071310;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;'de novo' protein folding#GO:0006458;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;COP9 signalosome#GO:0008180;vesicle#GO:0031982;intracellular organelle#GO:0043229 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 HUMAN|HGNC=20639|UniProtKB=P59551 P59551 TAS2R60 PTHR11394:SF32 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 60 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=7830|UniProtKB=Q16617 Q16617 NKG7 PTHR10671:SF34 EPITHELIAL MEMBRANE PROTEIN-RELATED PROTEIN NKG7 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=6167|UniProtKB=P19823 P19823 ITIH2 PTHR10338:SF14 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H2 protease inhibitor#PC00191 HUMAN|HGNC=6914|UniProtKB=P56270 P56270 MAZ PTHR24390:SF122 ZINC FINGER PROTEIN MYC-ASSOCIATED ZINC FINGER PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=38601|UniProtKB=Q6ZUB0 Q6ZUB0 SPATA31D4 PTHR21859:SF50 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31D3-RELATED HUMAN|HGNC=21573|UniProtKB=Q6NT16 Q6NT16 SLC18B1 PTHR23506:SF26 FAMILY NOT NAMED MFS-TYPE TRANSPORTER SLC18B1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 secondary carrier transporter#PC00258 HUMAN|HGNC=6285|UniProtKB=Q16558 Q16558 KCNMB1 PTHR10258:SF1 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;transporter activity#GO:0005215;channel activity#GO:0015267;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 response to metal ion#GO:0010038;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to inorganic substance#GO:0010035;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=24113|UniProtKB=Q9H7F0 Q9H7F0 ATP13A3 PTHR45630:SF12 CATION-TRANSPORTING ATPASE-RELATED CATION-TRANSPORTING ATPASE 13A3-RELATED cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 HUMAN|HGNC=9718|UniProtKB=P49023 P49023 PXN PTHR24216:SF11 PAXILLIN-RELATED PAXILLIN transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 signal transduction#GO:0007165;response to growth factor#GO:0070848;developmental process#GO:0032502;biological adhesion#GO:0022610;substrate adhesion-dependent cell spreading#GO:0034446;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;signaling#GO:0023052;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cell morphogenesis involved in differentiation#GO:0000904;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;localization of cell#GO:0051674;cell morphogenesis#GO:0000902;cell communication#GO:0007154;cell adhesion#GO:0007155;cell motility#GO:0048870;cell-substrate adhesion#GO:0031589;endothelial cell migration#GO:0043542;cellular process#GO:0009987;localization#GO:0051179;cell development#GO:0048468;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;cell migration#GO:0016477;locomotion#GO:0040011 cytoplasm#GO:0005737;anchoring junction#GO:0070161;intracellular#GO:0005622;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 CCKR signaling map#P06959>Paxillin#P07145;Angiogenesis#P00005>Paxillin#P00194;Gonadotropin-releasing hormone receptor pathway#P06664>Paxillin#P06784;VEGF signaling pathway#P00056>Paxillin#P01418;Integrin signalling pathway#P00034>Paxillin#P00950 HUMAN|HGNC=7882|UniProtKB=Q04721 Q04721 NOTCH2 PTHR45836:SF15 SLIT HOMOLOG NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2-RELATED neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330;Notch signaling pathway#GO:0007219 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Notch signaling pathway#P00045>Notch#P01099;Angiogenesis#P00005>Notch#P00255;Notch signaling pathway#P00045>NIct#P01119;Alzheimer disease-presenilin pathway#P00004>Notch N-terminal fragment#P00171;Notch signaling pathway#P00045>NIcs#P01120;Notch signaling pathway#P00045>Ntm#P01114;Alzheimer disease-presenilin pathway#P00004>Notch C-terminal fragment#P00120;Notch signaling pathway#P00045>Next#P01103;Alzheimer disease-presenilin pathway#P00004>NICD#P00122;Alzheimer disease-presenilin pathway#P00004>Notch#P00176;Alzheimer disease-presenilin pathway#P00004>Notch fragment#P00154;Alzheimer disease-presenilin pathway#P00004>Notch transmembrane fragment#P00135;Alzheimer disease-presenilin pathway#P00004>Notch extracellular fragment#P00179 HUMAN|HGNC=6765|UniProtKB=Q13477 Q13477 MADCAM1 PTHR14162:SF1 MUCOSAL ADDRESSIN CELL ADHESION MOLECULE-1 MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;regulation of locomotion#GO:0040012;biological adhesion#GO:0022610;regulation of localization#GO:0032879;positive regulation of cellular component movement#GO:0051272;leukocyte cell-cell adhesion#GO:0007159;positive regulation of leukocyte migration#GO:0002687;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;integrin-mediated signaling pathway#GO:0007229;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cellular component movement#GO:0051270;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;immune system process#GO:0002376;positive regulation of cell migration#GO:0030335;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011 HUMAN|HGNC=17715|UniProtKB=Q8N6N7 Q8N6N7 ACBD7 PTHR23310:SF51 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 7 transfer/carrier protein#PC00219 HUMAN|HGNC=11640|UniProtKB=Q9HCS4 Q9HCS4 TCF7L1 PTHR10373:SF25 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7-LIKE 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>TCF#P06701;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Cadherin signaling pathway#P00012>TCF/LEF#P00465 HUMAN|HGNC=24131|UniProtKB=Q9UHQ4 Q9UHQ4 BCAP29 PTHR12701:SF5 BCR-ASSOCIATED PROTEIN, BAP B-CELL RECEPTOR-ASSOCIATED PROTEIN 29 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=26750|UniProtKB=Q8N9C0 Q8N9C0 IGSF22 PTHR13817:SF153 TITIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 22 HUMAN|HGNC=19741|UniProtKB=Q9NXS3 Q9NXS3 KLHL28 PTHR24412:SF441 KELCH PROTEIN KELCH-LIKE PROTEIN 28 scaffold/adaptor protein#PC00226 HUMAN|HGNC=13311|UniProtKB=Q96QA5 Q96QA5 GSDMA PTHR16399:SF18 GASDERMIN GASDERMIN-A HUMAN|HGNC=23336|UniProtKB=A8K2U0 A8K2U0 A2ML1 PTHR11412:SF140 MACROGLOBULIN / COMPLEMENT ALPHA-2-MACROGLOBULIN-LIKE PROTEIN 1 protease inhibitor#PC00191 HUMAN|HGNC=15801|UniProtKB=A9Z1Z3 A9Z1Z3 FER1L4 PTHR12546:SF36 FER-1-LIKE FER-1-LIKE PROTEIN 4 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024;plasma membrane organization#GO:0007009 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=12621|UniProtKB=Q9UPT9 Q9UPT9 USP22 PTHR21646:SF40 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 22 cysteine protease#PC00081 HUMAN|HGNC=6729|UniProtKB=O60449 O60449 LY75 PTHR22803:SF65 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED LYMPHOCYTE ANTIGEN 75 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 HUMAN|HGNC=30029|UniProtKB=Q32NB8 Q32NB8 PGS1 PTHR12586:SF1 CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL transferase#PC00220 HUMAN|HGNC=25681|UniProtKB=Q3KP44 Q3KP44 ANKRD55 PTHR24123:SF85 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 55 scaffold/adaptor protein#PC00226 HUMAN|HGNC=14064|UniProtKB=Q9UBN7 Q9UBN7 HDAC6 PTHR48252:SF38 HISTONE DEACETYLASE 2-RELATED HISTONE DEACETYLASE 6 HUMAN|HGNC=9842|UniProtKB=Q12967 Q12967 RALGDS PTHR23113:SF35 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR guanyl-nucleotide exchange factor#PC00113 Ras Pathway#P04393>RalGDS#P04551 HUMAN|HGNC=20080|UniProtKB=Q70EL2 Q70EL2 USP45 PTHR21646:SF34 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 45 cysteine protease#PC00081 HUMAN|HGNC=18132|UniProtKB=Q9P2J2 Q9P2J2 IGSF9 PTHR10075:SF25 BASIGIN RELATED PROTEIN TURTLE HOMOLOG A cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=23227|UniProtKB=Q8WVF5 Q8WVF5 KCTD4 PTHR14499:SF9 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD4 scaffold/adaptor protein#PC00226 HUMAN|HGNC=125|UniProtKB=P15309 P15309 ACP3 PTHR11567:SF32 ACID PHOSPHATASE-RELATED PROSTATIC ACID PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lysosome organization#GO:0007040;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;dephosphorylation#GO:0016311;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphatase#PC00181 HUMAN|HGNC=18476|UniProtKB=Q71UM5 Q71UM5 RPS27L PTHR11594:SF2 40S RIBOSOMAL PROTEIN S27 40S RIBOSOMAL PROTEIN S27-LIKE structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;ribonucleoprotein complex subunit organization#GO:0071826;ribonucleoprotein complex assembly#GO:0022618;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;ribosome biogenesis#GO:0042254;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=18561|UniProtKB=Q8TDH9 Q8TDH9 BLOC1S5 PTHR31784:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622;BLOC-1 complex#GO:0031083 HUMAN|HGNC=28439|UniProtKB=Q8WUX9 Q8WUX9 CHMP7 PTHR22761:SF21 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 7 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=4131|UniProtKB=Q9HCQ5 Q9HCQ5 GALNT9 PTHR11675:SF28 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 9 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=23640|UniProtKB=Q6U7Q0 Q6U7Q0 ZNF322 PTHR23226:SF187 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 322 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6633|UniProtKB=Q9NZU5 Q9NZU5 LMCD1 PTHR24211:SF0 LIM DOMAIN-CONTAINING PROTEIN LIM AND CYSTEINE-RICH DOMAINS PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=13552|UniProtKB=P98196 P98196 ATP11A PTHR24092:SF33 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IH-RELATED pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=14784|UniProtKB=Q8WZ94 Q8WZ94 OR5P3 PTHR26452:SF310 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=11859|UniProtKB=O14817 O14817 TSPAN4 PTHR19282:SF40 TETRASPANIN TETRASPANIN-4 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=10045|UniProtKB=P10153 P10153 RNASE2 PTHR11437:SF62 RIBONUCLEASE NON-SECRETORY RIBONUCLEASE ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952;locomotion#GO:0040011;chemotaxis#GO:0006935;taxis#GO:0042330 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=2851|UniProtKB=Q16760 Q16760 DGKD PTHR11255:SF30 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE DELTA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 HUMAN|HGNC=6598|UniProtKB=P18858 P18858 LIG1 PTHR45674:SF4 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 1 ligase activity#GO:0016874;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;nucleobase-containing compound catabolic process#GO:0034655;cellular response to stress#GO:0033554;DNA replication#GO:0006260;cellular macromolecule catabolic process#GO:0044265;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA ligase#PC00012 HUMAN|HGNC=4659|UniProtKB=P78347 P78347 GTF2I PTHR46304:SF2 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1 GENERAL TRANSCRIPTION FACTOR II-I sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 general transcription factor#PC00259 HUMAN|HGNC=25909|UniProtKB=Q8N4T4 Q8N4T4 ARHGEF39 PTHR47056:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39 regulation of cellular component movement#GO:0051270;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;regulation of localization#GO:0032879;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular component movement#GO:0051272;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;positive regulation of cell migration#GO:0030335;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=18553|UniProtKB=Q9Y342 Q9Y342 PLLP PTHR22776:SF9 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PLASMOLIPIN structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=5271|UniProtKB=Q9NNZ3 Q9NNZ3 DNAJC4 PTHR44825:SF1 FAMILY NOT NAMED DNAJ HOMOLOG SUBFAMILY C MEMBER 4 HUMAN|HGNC=13632|UniProtKB=Q92585 Q92585 MAML1 PTHR15692:SF19 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 1 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Notch signaling pathway#P00045>Mastermind#P01106 HUMAN|HGNC=25981|UniProtKB=Q9NXH8 Q9NXH8 TOR4A PTHR10760:SF1 TORSIN TORSIN-4A pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=29788|UniProtKB=Q9H2K0 Q9H2K0 MTIF3 PTHR10938:SF0 TRANSLATION INITIATION FACTOR IF-3 TRANSLATION INITIATION FACTOR IF-3, MITOCHONDRIAL nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;cellular process#GO:0009987;organelle organization#GO:0006996;organelle disassembly#GO:1903008 translation initiation factor#PC00224 HUMAN|HGNC=6157|UniProtKB=Q13352 Q13352 ITGB3BP PTHR15581:SF0 CENTROMERE PROTEIN R CENTROMERE PROTEIN R HUMAN|HGNC=4397|UniProtKB=Q9BYB4 Q9BYB4 GNB1L PTHR19854:SF1 TRANSDUCIN BETA-LIKE 3 GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28472|UniProtKB=Q9BTV4 Q9BTV4 TMEM43 PTHR13416:SF2 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 43 HUMAN|HGNC=28945|UniProtKB=Q15061 Q15061 WDR43 PTHR44267:SF1 WD REPEAT-CONTAINING PROTEIN 43 WD REPEAT-CONTAINING PROTEIN 43 HUMAN|HGNC=28112|UniProtKB=Q15024 Q15024 EXOSC7 PTHR11097:SF8 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP42 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;exosome (RNase complex)#GO:0000178;intracellular organelle#GO:0043229 exoribonuclease#PC00099 HUMAN|HGNC=11575|UniProtKB=Q86VP1 Q86VP1 TAX1BP1 PTHR31915:SF8 SKICH DOMAIN-CONTAINING PROTEIN TAX1-BINDING PROTEIN 1 HUMAN|HGNC=439|UniProtKB=P05187 P05187 ALPP PTHR11596:SF69 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE, PLACENTAL TYPE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=25911|UniProtKB=Q96C01 Q96C01 FAM136A PTHR21096:SF0 UNCHARACTERIZED PROTEIN FAM136A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9827|UniProtKB=Q99638 Q99638 RAD9A PTHR15237:SF1 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;intra-S DNA damage checkpoint#GO:0031573;regulation of biological process#GO:0050789;cellular response to abiotic stimulus#GO:0071214;cell cycle checkpoint#GO:0000075;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;response to abiotic stimulus#GO:0009628;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;response to ionizing radiation#GO:0010212;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;cellular metabolic process#GO:0044237;mitotic DNA damage checkpoint#GO:0044773;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;mitotic DNA integrity checkpoint#GO:0044774;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;DNA replication checkpoint#GO:0000076;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;cellular response to environmental stimulus#GO:0104004;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 exodeoxyribonuclease#PC00098 HUMAN|HGNC=28514|UniProtKB=Q8N8E3 Q8N8E3 CEP112 PTHR18871:SF2 CENTROSOMAL PROTEIN OF 112 KDA CENTROSOMAL PROTEIN OF 112 KDA HUMAN|HGNC=20610|UniProtKB=O60346 O60346 PHLPP1 PTHR45752:SF58 LEUCINE-RICH REPEAT-CONTAINING PH DOMAIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN PHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6237|UniProtKB=Q9NSA2 Q9NSA2 KCND1 PTHR11537:SF174 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=18022|UniProtKB=Q96A56 Q96A56 TP53INP1 PTHR31671:SF0 DIABETES AND OBESITY REGULATED, ISOFORM G TUMOR PROTEIN P53-INDUCIBLE NUCLEAR PROTEIN 1 positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;organelle assembly#GO:0070925;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229 HUMAN|HGNC=11513|UniProtKB=O00445 O00445 SYT5 PTHR10024:SF282 SYNAPTOTAGMIN SYNAPTOTAGMIN-5 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;syntaxin binding#GO:0019905;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;synaptic signaling#GO:0099536;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;neurotransmitter secretion#GO:0007269;response to inorganic substance#GO:0010035;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;exocytic process#GO:0140029;cellular component organization or biogenesis#GO:0071840;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;regulation of neurotransmitter levels#GO:0001505;regulation of ion transport#GO:0043269;export from cell#GO:0140352;vesicle fusion#GO:0006906;regulation of signaling#GO:0023051;transport#GO:0006810;cation transport#GO:0006812;organic substance transport#GO:0071702;regulation of transport#GO:0051049;neurotransmitter transport#GO:0006836;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;response to metal ion#GO:0010038;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;response to chemical#GO:0042221;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 HUMAN|HGNC=6702|UniProtKB=Q32MZ4 Q32MZ4 LRRFIP1 PTHR19212:SF5 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 DNA-binding transcription factor#PC00218 HUMAN|HGNC=1438|UniProtKB=P10092 P10092 CALCB PTHR10505:SF3 CALCITONIN-RELATED CALCITONIN GENE-RELATED PEPTIDE 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 peptide hormone#PC00179 HUMAN|HGNC=12155|UniProtKB=P0DTU4 P0DTU4 TRB PTHR23266:SF340 IMMUNOGLOBULIN HEAVY CHAIN T CELL RECEPTOR BETA CHAIN MC.7.G5-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 T cell activation#P00053>TCR Beta#P01299 HUMAN|HGNC=1607|UniProtKB=P51684 P51684 CCR6 PTHR10489:SF611 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 6 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=22958|UniProtKB=Q9NR12 Q9NR12 PDLIM7 PTHR24214:SF0 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 7 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=29028|UniProtKB=Q2TAZ0 Q2TAZ0 ATG2A PTHR13190:SF21 AUTOPHAGY-RELATED 2, ISOFORM A AUTOPHAGY-RELATED PROTEIN 2 HOMOLOG A phosphatidylinositol-3-phosphate binding#GO:0032266;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;macroautophagy#GO:0016236;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;autophagy of mitochondrion#GO:0000422;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;lysosomal microautophagy#GO:0016237;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;autophagy#GO:0006914;autophagy of nucleus#GO:0044804;piecemeal microautophagy of the nucleus#GO:0034727 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020;intracellular#GO:0005622;extrinsic component of membrane#GO:0019898 HUMAN|HGNC=25487|UniProtKB=Q9NWA0 Q9NWA0 MED9 PTHR20844:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 9 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=16143|UniProtKB=Q9BTV7 Q9BTV7 CABLES2 PTHR22896:SF3 CDK5 AND ABL1 ENZYME SUBSTRATE 1 CDK5 AND ABL1 ENZYME SUBSTRATE 2 HUMAN|HGNC=21168|UniProtKB=Q8IXI2 Q8IXI2 RHOT1 PTHR24072:SF124 RHO FAMILY GTPASE MITOCHONDRIAL RHO GTPASE 1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;organelle localization#GO:0051640;regulation of organelle organization#GO:0033043;transport#GO:0006810;microtubule-based movement#GO:0007018;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of mitochondrion organization#GO:0010821;regulation of cellular process#GO:0050794;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;mitochondrion organization#GO:0007005;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;organelle transport along microtubule#GO:0072384 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;integral component of mitochondrial outer membrane#GO:0031307 small GTPase#PC00208 HUMAN|HGNC=6864|UniProtKB=Q12851 Q12851 MAP4K2 PTHR48012:SF6 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 2 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;MAP kinase kinase activity#GO:0004708;protein kinase activity#GO:0004672 Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCK#P00268 HUMAN|HGNC=8598|UniProtKB=Q8TE04 Q8TE04 PANK1 PTHR12280:SF23 PANTOTHENATE KINASE PANTOTHENATE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 HUMAN|HGNC=8489|UniProtKB=Q9UBD5 Q9UBD5 ORC3 PTHR12748:SF1 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;nuclear DNA replication#GO:0033260;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;pre-replicative complex assembly involved in nuclear cell cycle DNA replication#GO:0006267;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;nuclear chromosome, telomeric region#GO:0000784;pre-replicative complex#GO:0036387;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pre-replicative complex#GO:0005656;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;MCM core complex#GO:0097373;chromosome#GO:0005694;intracellular#GO:0005622;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 replication origin binding protein#PC00199 HUMAN|HGNC=12542|UniProtKB=P0DTE4 P0DTE4 UGT2A1 PTHR48043:SF140 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2A1 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=19156|UniProtKB=Q8NFW9 Q8NFW9 MYRIP PTHR14555:SF6 MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED MYELIN-ASSOCIATED OLIGODENDROCYTE BASIC PROTEIN-RELATED cytoskeletal protein binding#GO:0008092;Ras GTPase binding#GO:0017016;myosin binding#GO:0017022;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;actin binding#GO:0003779;Rab GTPase binding#GO:0017137 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;intracellular organelle#GO:0043229 myelin protein#PC00161 HUMAN|HGNC=1112|UniProtKB=Q15003 Q15003 NCAPH PTHR13108:SF9 CONDENSIN COMPLEX SUBUNIT 2 CONDENSIN COMPLEX SUBUNIT 2 nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;DNA-dependent ATPase activity#GO:0008094;isomerase activity#GO:0016853;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ATPase activator activity#GO:0001671;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic chromosome condensation#GO:0007076;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=14933|UniProtKB=Q9NXA8 Q9NXA8 SIRT5 PTHR48252:SF55 HISTONE DEACETYLASE 2-RELATED NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL HUMAN|HGNC=4667|UniProtKB=Q9UKN8 Q9UKN8 GTF3C4 PTHR15496:SF2 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 general transcription factor#PC00259 HUMAN|HGNC=11274|UniProtKB=P11277 P11277 SPTB PTHR11915:SF248 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, ERYTHROCYTIC HUMAN|HGNC=31111|UniProtKB=A6NH57 A6NH57 ARL5C PTHR11711:SF148 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5C-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 G-protein#PC00020 HUMAN|HGNC=4022|UniProtKB=Q9Y5J6 Q9Y5J6 TIMM10B PTHR13172:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 B envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758 primary active transporter#PC00068 HUMAN|HGNC=7566|UniProtKB=P23409 P23409 MYF6 PTHR11534:SF4 MYOGENIC FACTOR MYOGENIC FACTOR 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;nucleobase-containing compound metabolic process#GO:0006139;muscle structure development#GO:0061061;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of cell differentiation#GO:0045597;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of developmental process#GO:0051094;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=2186|UniProtKB=P12107 P12107 COL11A1 PTHR24023:SF42 COLLAGEN ALPHA COLLAGEN ALPHA-1(XI) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;extracellular region#GO:0005576;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=5645|UniProtKB=A0A0C4DH34 A0A0C4DH34 IGHV4-28 PTHR23266:SF361 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 4-28 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=28006|UniProtKB=Q8WVK7 Q8WVK7 SKA2 PTHR32017:SF3 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;chromosome, centromeric region#GO:0000775;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;condensed chromosome outer kinetochore#GO:0000940;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 HUMAN|HGNC=31038|UniProtKB=Q9H6N6 Q9H6N6 MYH16 PTHR23159:SF33 CENTROSOMAL PROTEIN 2 MYOSIN HEAVY CHAIN, CARDIAC MUSCLE ISOFORM chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=23354|UniProtKB=Q8ND76 Q8ND76 CCNY PTHR14248:SF33 CYCLIN Y, ISOFORM A CYCLIN-Y cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;positive regulation of cell cycle#GO:0045787;positive regulation of protein modification process#GO:0031401;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 HUMAN|HGNC=1452|UniProtKB=P27482 P27482 CALML3 PTHR23050:SF389 CALCIUM BINDING PROTEIN CALMODULIN-LIKE PROTEIN 3 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755 HUMAN|HGNC=26434|UniProtKB=Q6P1S2 Q6P1S2 C3orf33 PTHR28434:SF1 PROTEIN C3ORF33 PROTEIN C3ORF33 HUMAN|HGNC=8704|UniProtKB=Q9Y5G7 Q9Y5G7 PCDHGA6 PTHR24028:SF107 CADHERIN-87A PROTOCADHERIN GAMMA-A6 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=10627|UniProtKB=P10147 P10147 CCL3 PTHR12015:SF174 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 3 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=26129|UniProtKB=Q86YV0 Q86YV0 RASAL3 PTHR10194:SF96 RAS GTPASE-ACTIVATING PROTEINS RAS PROTEIN ACTIVATOR LIKE-3 GTPase-activating protein#PC00257 HUMAN|HGNC=21090|UniProtKB=Q5T215 Q5T215 TRAPPC3L PTHR13048:SF1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3-LIKE PROTEIN localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=29113|UniProtKB=Q6IC98 Q6IC98 GRAMD4 PTHR37402:SF1 GRAM DOMAIN-CONTAINING PROTEIN 4 GRAM DOMAIN-CONTAINING PROTEIN 4 positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;pattern recognition receptor signaling pathway#GO:0002221;regulation of catalytic activity#GO:0050790;positive regulation of metabolic process#GO:0009893;positive regulation of programmed cell death#GO:0043068;cell death#GO:0008219;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell death#GO:0010942 HUMAN|HGNC=13015|UniProtKB=Q9UK12 Q9UK12 ZNF222 PTHR24377:SF612 IP01015P-RELATED ZINC FINGER PROTEIN 222-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24026|UniProtKB=Q8TDY3 Q8TDY3 ACTRT2 PTHR11937:SF38 ACTIN ACTIN-RELATED PROTEIN T2 actin and actin related protein#PC00039 HUMAN|HGNC=18718|UniProtKB=Q8WU67 Q8WU67 ABHD3 PTHR10794:SF50 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PHOSPHOLIPASE ABHD3 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;acylglycerol lipase activity#GO:0047372;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620 lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 serine protease#PC00203 HUMAN|HGNC=29862|UniProtKB=Q8WWG1 Q8WWG1 NRG4 PTHR11100:SF20 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-2, MEMBRANE-BOUND ISOFORM-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 HUMAN|HGNC=24708|UniProtKB=Q49AA0 Q49AA0 ZFP69 PTHR24381:SF74 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 69 HOMOLOG DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=24426|UniProtKB=Q8N1L4 Q8N1L4 CYP4Z2P PTHR24291:SF39 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4A11-RELATED oxygenase#PC00177 HUMAN|HGNC=21206|UniProtKB=P0C6S8 P0C6S8 LINGO3 PTHR24373:SF130 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 3 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=5178|UniProtKB=P23327 P23327 HRC PTHR15054:SF3 HISTIDINE-RICH CALCIUM-BINDING PROTEIN-RELATED SARCOPLASMIC RETICULUM HISTIDINE-RICH CALCIUM-BINDING PROTEIN HUMAN|HGNC=16298|UniProtKB=Q504T8 Q504T8 MIDN PTHR23010:SF1 MIDNOLIN MIDNOLIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=12240|UniProtKB=A0A1B0GX31 A0A1B0GX31 TRBV7-6 PTHR23268:SF78 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 7-4-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=16642|UniProtKB=Q9H2A7 Q9H2A7 CXCL16 PTHR14385:SF0 CXC CHEMOKINE LIGAND C-X-C MOTIF CHEMOKINE 16 molecular adaptor activity#GO:0060090;low-density lipoprotein particle binding#GO:0030169;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;protein-containing complex binding#GO:0044877;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;cytokine receptor binding#GO:0005126 regulation of locomotion#GO:0040012;regulation of localization#GO:0032879;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;positive regulation of cell motility#GO:2000147;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;chemotaxis#GO:0006935;regulation of cellular component movement#GO:0051270;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;positive regulation of cell migration#GO:0030335;lymphocyte migration#GO:0072676;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=1985|UniProtKB=O14578 O14578 CIT PTHR22988:SF71 MYOTONIC DYSTROPHY S/T KINASE-RELATED CITRON RHO-INTERACTING KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;actomyosin structure organization#GO:0031032;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;actin cytoskeleton organization#GO:0030036;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=1273|UniProtKB=P0DPI2 P0DPI2 GATD3A PTHR10224:SF9 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 3A, MITOCHONDRIAL-RELATED cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6649|UniProtKB=Q0VAK6 Q0VAK6 LMOD3 PTHR10901:SF3 TROPOMODULIN LEIOMODIN-3 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=30661|UniProtKB=Q9UBT2 Q9UBT2 UBA2 PTHR10953:SF5 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 2 ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 HUMAN|HGNC=43788|UniProtKB=Q8NHM4 Q8NHM4 PRSS3P2 PTHR24264:SF64 TRYPSIN-RELATED TRYPSIN-6-RELATED serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=8127|UniProtKB=O15294 O15294 OGT PTHR44366:SF1 UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 protein modifying enzyme#PC00260 HUMAN|HGNC=19836|UniProtKB=Q8N7A1 Q8N7A1 KLHDC1 PTHR46228:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=7700|UniProtKB=O43674 O43674 NDUFB5 PTHR13178:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SGDH SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 5, MITOCHONDRIAL envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|Gene=SNG2L_HUMAN|UniProtKB=A8MWL6 A8MWL6 - PTHR10838:SF19 SYNAPTOGYRIN SYNAPTOGYRIN-2 LIKE PROTEIN-RELATED synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=5643|UniProtKB=A0A075B7F1 A0A075B7F1 IGHV3OR16-8 PTHR23266:SF302 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=21094|UniProtKB=Q5JW98 Q5JW98 CALHM4 PTHR32261:SF5 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=12109|UniProtKB=A0A0B4J235 A0A0B4J235 TRAV13-2 PTHR19433:SF117 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 13-2 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=28617|UniProtKB=Q8N350 Q8N350 CBARP PTHR28597:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT-ASSOCIATED REGULATORY PROTEIN VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT-ASSOCIATED REGULATORY PROTEIN ion channel binding#GO:0044325;protein binding#GO:0005515;binding#GO:0005488 vesicle fusion#GO:0006906;negative regulation of biological process#GO:0048519;membrane organization#GO:0061024;regulation of metal ion transport#GO:0010959;organelle membrane fusion#GO:0090174;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;calcium ion transport#GO:0006816;regulation of vesicle-mediated transport#GO:0060627;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of secretion#GO:0051046;secretion#GO:0046903;divalent inorganic cation transport#GO:0072511;vesicle organization#GO:0016050;regulation of transmembrane transporter activity#GO:0022898;calcium-ion regulated exocytosis#GO:0017156;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;regulation of calcium ion transport#GO:0051924;vesicle-mediated transport#GO:0016192;negative regulation of transport#GO:0051051;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;ion transmembrane transport#GO:0034220;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of ion transmembrane transport#GO:0034765;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;export from cell#GO:0140352;negative regulation of molecular function#GO:0044092 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=9634|UniProtKB=Q93096 Q93096 PTP4A1 PTHR23339:SF55 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 HUMAN|HGNC=28722|UniProtKB=Q5HYK3 Q5HYK3 COQ5 PTHR43591:SF24 METHYLTRANSFERASE 2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155 HUMAN|HGNC=3387|UniProtKB=P29320 P29320 EPHA3 PTHR24416:SF18 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 HUMAN|HGNC=2042|UniProtKB=P56880 P56880 CLDN20 PTHR12002:SF17 CLAUDIN CLAUDIN-20 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=15564|UniProtKB=Q9NZH7 Q9NZH7 IL36B PTHR10078:SF24 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-36 BETA receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;response to cytokine#GO:0034097;regulation of cell-cell adhesion#GO:0022407;gene expression#GO:0010467;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;regulation of leukocyte cell-cell adhesion#GO:1903037;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;cell adhesion#GO:0007155;positive regulation of T cell differentiation#GO:0045582;positive regulation of macromolecule metabolic process#GO:0010604;response to lipopolysaccharide#GO:0032496;T cell differentiation#GO:0030217;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to stress#GO:0006950;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;cellular response to lipopolysaccharide#GO:0071222;animal organ development#GO:0048513;biological adhesion#GO:0022610;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;response to lipid#GO:0033993;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cellular response to lipid#GO:0071396;inflammatory response#GO:0006954;leukocyte cell-cell adhesion#GO:0007159;system development#GO:0048731;cell differentiation#GO:0030154;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of metabolic process#GO:0009893;regulation of hemopoiesis#GO:1903706;positive regulation of leukocyte cell-cell adhesion#GO:1903039;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;positive regulation of cell differentiation#GO:0045597;immune response#GO:0006955;multicellular organism development#GO:0007275;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;lymphocyte differentiation#GO:0030098;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of T cell activation#GO:0050870;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interleukin superfamily#PC00128 HUMAN|HGNC=20292|UniProtKB=Q9Y376 Q9Y376 CAB39 PTHR10182:SF11 CALCIUM-BINDING PROTEIN 39-RELATED CALCIUM-BINDING PROTEIN 39 protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209;kinase binding#GO:0019900;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 HUMAN|HGNC=16658|UniProtKB=Q96BY2 Q96BY2 MOAP1 PTHR23095:SF14 PARANEOPLASTIC ANTIGEN MODULATOR OF APOPTOSIS 1 regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=13410|UniProtKB=Q96QS1 Q96QS1 TSPAN32 PTHR19282:SF426 TETRASPANIN TETRASPANIN-32 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=12518|UniProtKB=P55851 P55851 UCP2 PTHR45618:SF1 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to stress#GO:0006950;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;response to cold#GO:0009409;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152 secondary carrier transporter#PC00258 HUMAN|HGNC=465|UniProtKB=Q16671 Q16671 AMHR2 PTHR23255:SF49 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ANTI-MUELLERIAN HORMONE TYPE-2 RECEPTOR signaling receptor activity#GO:0038023;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;transforming growth factor beta receptor signaling pathway#GO:0007179;phosphorus metabolic process#GO:0006793;response to transforming growth factor beta#GO:0071559;phosphate-containing compound metabolic process#GO:0006796;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;response to BMP#GO:0071772;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>MISRII#P06792;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277 HUMAN|HGNC=33708|UniProtKB=A6NLP5 A6NLP5 TTC36 PTHR21405:SF0 CDNA SEQUENCE BC021608 TETRATRICOPEPTIDE REPEAT PROTEIN 36 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 HUMAN|HGNC=2673|UniProtKB=P51398 P51398 DAP3 PTHR12810:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S29 28S RIBOSOMAL PROTEIN S29, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 HUMAN|HGNC=13717|UniProtKB=Q9UJA9 Q9UJA9 ENPP5 PTHR10151:SF120 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 5 HUMAN|HGNC=15832|UniProtKB=Q96G97 Q96G97 BSCL2 PTHR21212:SF0 BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN SEIPIN localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;maintenance of location#GO:0051235;biological regulation#GO:0065007;cellular component organization#GO:0016043;lipid localization#GO:0010876;lipid storage#GO:0019915;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=10707|UniProtKB=Q8WVN6 Q8WVN6 SECTM1 PTHR15123:SF5 SECRETED AND TRANSMEMBRANE PROTEIN 1 SECRETED AND TRANSMEMBRANE PROTEIN 1 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=5397|UniProtKB=P40305 P40305 IFI27 PTHR16932:SF15 INTERFERON ALPHA-INDUCIBLE PROTEIN 27 INTERFERON ALPHA-INDUCIBLE PROTEIN 27, MITOCHONDRIAL regulation of biological process#GO:0050789;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25942|UniProtKB=Q8IY21 Q8IY21 DDX60 PTHR44533:SF3 DEAD/H RNA HELICASE, PUTATIVE-RELATED ATP-DEPENDENT RNA HELICASE DDX60-RELATED HUMAN|HGNC=4413|UniProtKB=P36915 P36915 GNL1 PTHR45709:SF7 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 HUMAN|HGNC=28213|UniProtKB=Q3MUY2 Q3MUY2 PIGY PTHR39235:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Y PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Y lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=23530|UniProtKB=Q9ULE6 Q9ULE6 PALD1 PTHR23339:SF114 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PALADIN protein phosphatase#PC00195 HUMAN|HGNC=30553|UniProtKB=Q8IW03 Q8IW03 SIAH3 PTHR45877:SF5 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 SEVEN IN ABSENTIA HOMOLOG 3 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=23080|UniProtKB=Q7RTY7 Q7RTY7 OVCH1 PTHR24251:SF21 OVOCHYMASE-RELATED OVOCHYMASE-1 serine protease#PC00203 HUMAN|HGNC=15799|UniProtKB=Q9NQG1 Q9NQG1 MANBAL PTHR14409:SF0 MANNOSIDASE, BETA A, LYSOSOMAL-LIKE, MANBAL PROTEIN PROTEIN MANBAL HUMAN|Ensembl=ENSG00000179859|UniProtKB=A6NIN4 A6NIN4 RNF227 PTHR22791:SF14 UNCHARACTERIZED RING FINGER PROTEIN 227 HUMAN|HGNC=31670|UniProtKB=A6NNW6 A6NNW6 ENO4 PTHR11902:SF30 ENOLASE ENOLASE 4 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ATP generation from ADP#GO:0006757;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organelle fusion#GO:0048284;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;ADP metabolic process#GO:0046031;regulation of organelle organization#GO:0033043;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;vacuole fusion, non-autophagic#GO:0042144;regulation of cellular process#GO:0050794;glycolytic process#GO:0006096;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular#GO:0005622 lyase#PC00144 HUMAN|HGNC=17635|UniProtKB=Q9NZQ7 Q9NZQ7 CD274 PTHR25466:SF3 T-LYMPHOCYTE ACTIVATION ANTIGEN PROGRAMMED CELL DEATH 1 LIGAND 1 response to external biotic stimulus#GO:0043207;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to molecule of bacterial origin#GO:0002237;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;mononuclear cell proliferation#GO:0032943;negative regulation of T cell proliferation#GO:0042130;response to oxygen-containing compound#GO:1901700;negative regulation of T cell activation#GO:0050868;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;cell adhesion#GO:0007155;response to lipopolysaccharide#GO:0032496;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to lipopolysaccharide#GO:0071222;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;cellular response to lipid#GO:0071396;leukocyte cell-cell adhesion#GO:0007159;T cell proliferation#GO:0042098;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of leukocyte cell-cell adhesion#GO:1903039;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;regulation of T cell proliferation#GO:0042129;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=10302|UniProtKB=P30050 P30050 RPL12 PTHR11661:SF21 60S RIBOSOMAL PROTEIN L12 60S RIBOSOMAL PROTEIN L12 structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=12667|UniProtKB=Q9H320 Q9H320 VCX PTHR15251:SF2 TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED HUMAN|HGNC=27994|UniProtKB=A8MQ14 A8MQ14 ZNF850 PTHR24376:SF211 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 850 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=2743|UniProtKB=Q9UHI6 Q9UHI6 DDX20 PTHR47958:SF89 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX20-RELATED catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;intracellular#GO:0005622 HUMAN|HGNC=34500|UniProtKB=P0DMW5 P0DMW5 SMIM10L2B PTHR34446:SF3 SMALL INTEGRAL MEMBRANE PROTEIN 10 SMALL INTEGRAL MEMBRANE PROTEIN 10-LIKE PROTEIN 2A-RELATED HUMAN|HGNC=29826|UniProtKB=Q32MK0 Q32MK0 MYLK3 PTHR24347:SF394 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 HUMAN|HGNC=19692|UniProtKB=Q96F24 Q96F24 NRBF2 PTHR14964:SF5 NUCLEAR RECEPTOR BINDING FACTOR 2 NUCLEAR RECEPTOR-BINDING FACTOR 2 process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;phosphatidylinositol 3-kinase complex, class III#GO:0035032;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 transcription cofactor#PC00217 HUMAN|HGNC=13802|UniProtKB=Q9HD90 Q9HD90 NEUROD4 PTHR19290:SF86 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=24310|UniProtKB=Q53GL0 Q53GL0 PLEKHO1 PTHR15871:SF1 PH DOMAIN-CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY O MEMBER 1 HUMAN|HGNC=20794|UniProtKB=Q2NKX8 Q2NKX8 ERCC6L PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED HUMAN|HGNC=26089|UniProtKB=Q9NWK9 Q9NWK9 ZNHIT6 PTHR13483:SF3 UNCHARACTERIZED BOX C/D SNORNA PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of LSU-rRNA#GO:0000470 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7576|UniProtKB=P13533 P13533 MYH6 PTHR45615:SF11 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-6 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=7027|UniProtKB=Q12866 Q12866 MERTK PTHR24416:SF257 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE MER signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;phagocytosis#GO:0006909;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=13253|UniProtKB=Q9UBR5 Q9UBR5 CKLF PTHR22776:SF45 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CHEMOKINE-LIKE FACTOR intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=4024|UniProtKB=P51116 P51116 FXR2 PTHR10603:SF3 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;protein homodimerization activity#GO:0042803;organic cyclic compound binding#GO:0097159;binding#GO:0005488;identical protein binding#GO:0042802;protein binding#GO:0005515;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;cellular component biogenesis#GO:0044085;regulation of dendrite development#GO:0050773;regulation of response to DNA damage stimulus#GO:2001020;regulation of protein metabolic process#GO:0051246;heterocycle catabolic process#GO:0046700;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;central nervous system development#GO:0007417;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of translation#GO:0045727;macromolecule catabolic process#GO:0009057;regulation of multicellular organismal process#GO:0051239;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;positive regulation of macromolecule metabolic process#GO:0010604;RNA splicing#GO:0008380;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;multicellular organismal process#GO:0032501;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;plasma membrane bounded cell projection assembly#GO:0120031;translational elongation#GO:0006414;regulation of phosphorylation#GO:0042325;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;alternative mRNA splicing, via spliceosome#GO:0000380;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cell-cell signaling#GO:0007267;mRNA splicing, via spliceosome#GO:0000398;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;heterocycle metabolic process#GO:0046483;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cell morphogenesis#GO:0000902;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;positive regulation of protein metabolic process#GO:0051247;cell morphogenesis involved in neuron differentiation#GO:0048667;aromatic compound catabolic process#GO:0019439;regulation of neurogenesis#GO:0050767;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;cellular macromolecule catabolic process#GO:0044265;negative regulation of gene expression#GO:0010629;cellular localization#GO:0051641;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein modification process#GO:0031399;cell projection organization#GO:0030030;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;dendrite development#GO:0016358;microtubule-based movement#GO:0007018;regulation of synapse organization#GO:0050807;plasma membrane bounded cell projection organization#GO:0120036;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;mRNA metabolic process#GO:0016071;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;synaptic signaling#GO:0099536;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;regulation of dendritic spine development#GO:0060998;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;trans-synaptic signaling#GO:0099537;regulation of RNA stability#GO:0043487;negative regulation of protein metabolic process#GO:0051248;transport along microtubule#GO:0010970;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;neuron projection development#GO:0031175;synapse organization#GO:0050808;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;modulation of chemical synaptic transmission#GO:0050804;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;regulation of trans-synaptic signaling#GO:0099177;neuron projection morphogenesis#GO:0048812;intracellular transport#GO:0046907;regulation of synapse structure or activity#GO:0050803;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of cell morphogenesis involved in differentiation#GO:0010769;regulation of dendrite morphogenesis#GO:0048814;negative regulation of cellular metabolic process#GO:0031324;regulation of phosphate metabolic process#GO:0019220;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;macromolecule modification#GO:0043412;peptide metabolic process#GO:0006518;developmental process#GO:0032502;transport#GO:0006810;RNA processing#GO:0006396;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of cell differentiation#GO:0045595;translation#GO:0006412;positive regulation of response to stimulus#GO:0048584;axo-dendritic transport#GO:0008088;positive regulation of metabolic process#GO:0009893;cytoskeleton-dependent intracellular transport#GO:0030705;RNA catabolic process#GO:0006401;regulation of mRNA processing#GO:0050684;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;regulation of RNA metabolic process#GO:0051252;dendrite morphogenesis#GO:0048813;cell projection assembly#GO:0030031;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of RNA splicing#GO:0043484;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;microtubule-based transport#GO:0099111;regulation of cellular biosynthetic process#GO:0031326;microtubule-based process#GO:0007017;regulation of macromolecule metabolic process#GO:0060255;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell projection assembly#GO:0060491;cell junction organization#GO:0034330;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;establishment of localization in cell#GO:0051649;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 supramolecular complex#GO:0099080;synapse#GO:0045202;postsynaptic density#GO:0014069;intracellular membrane-bounded organelle#GO:0043231;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;distal axon#GO:0150034;plasma membrane region#GO:0098590;postsynapse#GO:0098794;polysome#GO:0005844;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;presynapse#GO:0098793;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;nucleus#GO:0005634;filopodium#GO:0030175;neuronal cell body#GO:0043025;cell junction#GO:0030054;cytoplasmic region#GO:0099568;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasmic ribonucleoprotein granule#GO:0036464;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell body#GO:0044297;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;growth cone#GO:0030426;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 translation factor#PC00223 HUMAN|HGNC=11905|UniProtKB=O14763 O14763 TNFRSF10B PTHR46330:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B positive regulation of apoptotic process#GO:0043065;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TRAIL-R#P00276;p53 pathway#P00059>KILLER/DR5#G01568 HUMAN|HGNC=44447|UniProtKB=D6RCP7 D6RCP7 USP17L19 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=25987|UniProtKB=Q9NXF7 Q9NXF7 DCAF16 PTHR16194:SF0 DDB1- AND CUL4-ASSOCIATED FACTOR 16 DDB1- AND CUL4-ASSOCIATED FACTOR 16 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 HUMAN|HGNC=7323|UniProtKB=Q9UHD8 Q9UHD8 SEPTIN9 PTHR18884:SF47 SEPTIN SEPTIN-9 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cell division#GO:0051301;cellular localization#GO:0051641;membrane fission#GO:0090148;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 HUMAN|HGNC=26293|UniProtKB=Q9C093 Q9C093 SPEF2 PTHR14919:SF0 KPL2-RELATED SPERM FLAGELLAR PROTEIN 2 HUMAN|HGNC=1544|UniProtKB=Q8IUK8 Q8IUK8 CBLN2 PTHR22923:SF50 CEREBELLIN-RELATED CEREBELLIN-2 HUMAN|HGNC=28600|UniProtKB=Q8NCQ7 Q8NCQ7 PROCA1 PTHR12253:SF17 RH14732P PROTEIN PROCA1 HUMAN|HGNC=29670|UniProtKB=Q3T906 Q3T906 GNPTAB PTHR24045:SF0 FAMILY NOT NAMED N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNITS ALPHA/BETA HUMAN|HGNC=5269|UniProtKB=P61604 P61604 HSPE1 PTHR10772:SF0 10 KDA HEAT SHOCK PROTEIN 10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;unfolded protein binding#GO:0051082;binding#GO:0005488;chaperone binding#GO:0051087 'de novo' protein folding#GO:0006458;cellular process#GO:0009987;chaperone-mediated protein folding#GO:0061077;protein folding#GO:0006457 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperonin#PC00073 HUMAN|HGNC=7090|UniProtKB=Q29983 Q29983 MICA PTHR16675:SF154 MHC CLASS I-RELATED MHC CLASS I POLYPEPTIDE-RELATED SEQUENCE A-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=22209|UniProtKB=Q9ULQ0 Q9ULQ0 STRIP2 PTHR13239:SF6 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 STRIATIN-INTERACTING PROTEIN 2 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=43603|UniProtKB=Q8NF67 Q8NF67 ANKRD20A12P PTHR24147:SF57 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 26-RELATED HUMAN|HGNC=15175|UniProtKB=Q8NGJ1 Q8NGJ1 OR4D6 PTHR48002:SF23 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D6 transmembrane signal receptor#PC00197 HUMAN|HGNC=17409|UniProtKB=Q96SR6 Q96SR6 ZNF382 PTHR24404:SF22 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 382 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=8907|UniProtKB=O95394 O95394 PGM3 PTHR45955:SF1 PHOSPHOACETYLGLUCOSAMINE MUTASE PHOSPHOACETYLGLUCOSAMINE MUTASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;UDP-N-acetylglucosamine metabolic process#GO:0006047;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;amino sugar metabolic process#GO:0006040;aromatic compound biosynthetic process#GO:0019438;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 mutase#PC00160 HUMAN|HGNC=6324|UniProtKB=P33176 P33176 KIF5B PTHR24115:SF513 KINESIN-RELATED KINESIN-1 HEAVY CHAIN pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;ATP-dependent microtubule motor activity, plus-end-directed#GO:0008574;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 neuron projection guidance#GO:0097485;microtubule-based protein transport#GO:0099118;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;axonogenesis#GO:0007409;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;protein localization to synapse#GO:0035418;cellular component organization#GO:0016043;peptide transport#GO:0015833;transport along microtubule#GO:0010970;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;taxis#GO:0042330;receptor localization to synapse#GO:0097120;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;developmental process#GO:0032502;transport#GO:0006810;cell projection morphogenesis#GO:0048858;amide transport#GO:0042886;axo-dendritic transport#GO:0008088;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;axon guidance#GO:0007411;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;synaptic vesicle transport#GO:0048489;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cell morphogenesis involved in differentiation#GO:0000904;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;microtubule-based transport#GO:0099111;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;microtubule-based process#GO:0007017;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;generation of neurons#GO:0048699 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=11036|UniProtKB=P13866 P13866 SLC5A1 PTHR11819:SF151 SOLUTE CARRIER FAMILY 5 SODIUM/GLUCOSE COTRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sugar transmembrane transporter activity#GO:0051119;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=16922|UniProtKB=Q9UPQ3 Q9UPQ3 AGAP1 PTHR45819:SF1 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=28856|UniProtKB=Q96A37 Q96A37 RNF166 PTHR46016:SF4 ZINC FINGER, RING/FYVE/PHD-TYPE E3 UBIQUITIN-PROTEIN LIGASE RNF166 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=6153|UniProtKB=P05556 P05556 ITGB1 PTHR10082:SF28 INTEGRIN BETA SUBUNIT INTEGRIN BETA-1 extracellular matrix binding#GO:0050840;integrin binding#GO:0005178;binding#GO:0005488;cytokine binding#GO:0019955;collagen binding#GO:0005518;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;chemokine binding#GO:0019956 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;biological adhesion#GO:0022610;localization of cell#GO:0051674;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052 membrane protein complex#GO:0098796;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;focal adhesion#GO:0005925;integral component of plasma membrane#GO:0005887;cell-substrate junction#GO:0030055;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 integrin#PC00126 CCKR signaling map#P06959>ITGB1#G07277;CCKR signaling map#P06959>ITGB1#P07113;Integrin signalling pathway#P00034>Integrin beta#P00931;CCKR signaling map#P06959>ITGB1#G06984;Gonadotropin-releasing hormone receptor pathway#P06664>alpha-beta integrin dimer#P06820;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 HUMAN|HGNC=11004|UniProtKB=Q14542 Q14542 SLC29A2 PTHR10332:SF8 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;carbohydrate derivative transport#GO:1901264;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810 intrinsic component of membrane#GO:0031224;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=932|UniProtKB=Q14032 Q14032 BAAT PTHR10824:SF18 ACYL-COENZYME A THIOESTERASE-RELATED BILE ACID-COA:AMINO ACID N-ACYLTRANSFERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 esterase#PC00097 HUMAN|HGNC=29532|UniProtKB=Q53QV2 Q53QV2 LBH PTHR14987:SF2 PROTEIN LBH-RELATED PROTEIN LBH positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=23213|UniProtKB=Q7Z7B1 Q7Z7B1 PIGW PTHR20661:SF0 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;cellular localization#GO:0051641;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to plasma membrane#GO:0072659;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein localization to cell periphery#GO:1990778;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;cellular macromolecule localization#GO:0070727;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=17872|UniProtKB=Q9H993 Q9H993 ARMT1 PTHR12260:SF6 UNCHARACTERIZED DAMAGE-CONTROL PHOSPHATASE ARMT1 HUMAN|HGNC=3762|UniProtKB=Q9NZU0 Q9NZU0 FLRT3 PTHR45712:SF12 AGAP008170-PA LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT3 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=11843|UniProtKB=O43897 O43897 TLL1 PTHR10127:SF860 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING TOLLOID-LIKE PROTEIN 1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=16451|UniProtKB=P0DN87 P0DN87 CGB7 PTHR11515:SF25 GLYCOPROTEIN HORMONE BETA CHAIN CHORIOGONADOTROPIN SUBUNIT BETA 7 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular#GO:0005622 peptide hormone#PC00179 HUMAN|HGNC=25048|UniProtKB=Q96HW7 Q96HW7 INTS4 PTHR20938:SF0 UNCHARACTERIZED INTEGRATOR COMPLEX SUBUNIT 4 HUMAN|HGNC=23761|UniProtKB=Q9NVX7 Q9NVX7 KBTBD4 PTHR47195:SF1 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=30802|UniProtKB=Q96AD5 Q96AD5 PNPLA2 PTHR12406:SF29 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;chemical homeostasis#GO:0048878;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 phospholipase#PC00186 HUMAN|HGNC=11085|UniProtKB=O75093 O75093 SLIT1 PTHR45836:SF3 SLIT HOMOLOG SLIT HOMOLOG 1 PROTEIN carbohydrate derivative binding#GO:0097367;binding#GO:0005488;heparin binding#GO:0008201;protein binding#GO:0005515;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 HUMAN|HGNC=6297|UniProtKB=O43525 O43525 KCNQ3 PTHR11537:SF5 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;calmodulin binding#GO:0005516;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=193|UniProtKB=Q13444 Q13444 ADAM15 PTHR11905:SF130 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 15 metallopeptidase activity#GO:0008237;integrin binding#GO:0005178;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102 response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;innate immune response#GO:0045087;defense response#GO:0006952;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=21704|UniProtKB=Q9BV99 Q9BV99 LRRC61 PTHR15454:SF26 NISCHARIN RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 61 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=2919|UniProtKB=P56179 P56179 DLX6 PTHR24327:SF26 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=29095|UniProtKB=O75157 O75157 TSC22D2 PTHR46894:SF1 TSC22 DOMAIN FAMILY PROTEIN 2 TSC22 DOMAIN FAMILY PROTEIN 2 HUMAN|HGNC=10396|UniProtKB=P62249 P62249 RPS16 PTHR21569:SF15 RIBOSOMAL PROTEIN S9 40S RIBOSOMAL PROTEIN S16 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=24728|UniProtKB=A2RTX5 A2RTX5 TARS3 PTHR11451:SF38 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE 2, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=17862|UniProtKB=Q9H4L4 Q9H4L4 SENP3 PTHR12606:SF16 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 3 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein-specific protease activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=27323|UniProtKB=P0C7A2 P0C7A2 FAM153B PTHR40712:SF2 FAMILY WITH SEQUENCE SIMILARITY 153 MEMBER C-RELATED PROTEIN FAM153A-RELATED HUMAN|HGNC=10483|UniProtKB=P21817 P21817 RYR1 PTHR13715:SF15 RYANODINE RECEPTOR AND IP3 RECEPTOR RYANODINE RECEPTOR 1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;metal ion binding#GO:0046872;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;cation binding#GO:0043169;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;calcium ion binding#GO:0005509;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;sequestering of calcium ion#GO:0051208;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;negative regulation of cellular process#GO:0048523;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;release of sequestered calcium ion into cytosol#GO:0051209;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;regulation of cellular localization#GO:0060341;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065;negative regulation of sequestering of calcium ion#GO:0051283 bounding membrane of organelle#GO:0098588;supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;vacuole#GO:0005773;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;non-membrane-bounded organelle#GO:0043228;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;sarcomere#GO:0030017;transmembrane transporter complex#GO:1902495;cytoplasmic vesicle membrane#GO:0030659;myofibril#GO:0030016;membrane protein complex#GO:0098796;sarcoplasmic reticulum#GO:0016529;intracellular vesicle#GO:0097708;Z disc#GO:0030018;sarcoplasm#GO:0016528;sarcoplasmic reticulum membrane#GO:0033017;ion channel complex#GO:0034702;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;contractile fiber#GO:0043292;cation channel complex#GO:0034703;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;I band#GO:0031674;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434;CCKR signaling map#P06959>RYR1/2/3#P07088;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441 HUMAN|HGNC=388|UniProtKB=P51857 P51857 AKR1D1 PTHR11732:SF211 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER D1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=9898|UniProtKB=Q9NTZ6 Q9NTZ6 RBM12 PTHR13976:SF31 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RNA-BINDING PROTEIN 12 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=11557|UniProtKB=Q16559 Q16559 TAL2 PTHR13864:SF21 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=27400|UniProtKB=Q8N431 Q8N431 RASGEF1C PTHR23113:SF186 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1C guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=1480|UniProtKB=P20807 P20807 CAPN3 PTHR10183:SF329 CALPAIN CALPAIN-3 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;programmed cell death#GO:0012501;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=7029|UniProtKB=P08581 P08581 MET PTHR24416:SF483 TYROSINE-PROTEIN KINASE RECEPTOR HEPATOCYTE GROWTH FACTOR RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;phagocytosis#GO:0006909;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=24252|UniProtKB=Q96GK7 Q96GK7 FAHD2A PTHR42796:SF3 FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 hydrolase#PC00121 HUMAN|HGNC=9971|UniProtKB=P40938 P40938 RFC3 PTHR11669:SF1 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 3 pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 HUMAN|HGNC=18113|UniProtKB=Q8NHH1 Q8NHH1 TTLL11 PTHR12241:SF154 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL11 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=25295|UniProtKB=Q71RH2 Q71RH2 TLCD3B PTHR13439:SF15 CT120 PROTEIN CERAMIDE SYNTHASE transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=17728|UniProtKB=Q8TBY8 Q8TBY8 PMFBP1 PTHR18881:SF2 POLYAMINE-MODULATED FACTOR 1-BINDING PROTEIN 1-RELATED POLYAMINE-MODULATED FACTOR 1-BINDING PROTEIN 1 HUMAN|HGNC=25355|UniProtKB=Q6XR72 Q6XR72 SLC30A10 PTHR45820:SF3 FI23527P1 ZINC TRANSPORTER 10 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=5456|UniProtKB=O00458 O00458 IFRD1 PTHR12354:SF6 INTERFERON-RELATED DEVELOPMENTAL REGULATOR INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=29810|UniProtKB=Q99549 Q99549 MPHOSPH8 PTHR24166:SF47 ROLLING PEBBLES, ISOFORM B M-PHASE PHOSPHOPROTEIN 8 HUMAN|HGNC=20441|UniProtKB=Q96FQ6 Q96FQ6 S100A16 PTHR11639:SF76 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A16 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;intracellular organelle#GO:0043229 calmodulin-related#PC00061 HUMAN|HGNC=17823|UniProtKB=Q9BUW7 Q9BUW7 C9orf16 PTHR34344:SF1 UPF0184 PROTEIN C9ORF16 UPF0184 PROTEIN C9ORF16 HUMAN|HGNC=24783|UniProtKB=Q3SXY7 Q3SXY7 LRIT3 PTHR45842:SF8 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT, IMMUNOGLOBULIN-LIKE DOMAIN AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=7996|UniProtKB=Q16656 Q16656 NRF1 PTHR20338:SF8 NUCLEAR RESPIRATORY FACTOR 1 NUCLEAR RESPIRATORY FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;core promoter sequence-specific DNA binding#GO:0001046;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=29132|UniProtKB=O94929 O94929 ABLIM3 PTHR24213:SF0 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=27815|UniProtKB=Q96C28 Q96C28 ZNF707 PTHR24390:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 707 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1683|UniProtKB=P09326 P09326 CD48 PTHR12080:SF55 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE CD48 ANTIGEN immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=16821|UniProtKB=P78316 P78316 NOP14 PTHR23183:SF0 NOP14 NUCLEOLAR PROTEIN 14 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 HUMAN|HGNC=17011|UniProtKB=Q9BUJ2 Q9BUJ2 HNRNPUL1 PTHR12381:SF41 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 1 HUMAN|HGNC=3364|UniProtKB=Q9Y5L3 Q9Y5L3 ENTPD2 PTHR11782:SF33 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2 nucleotide phosphatase#PC00173 HUMAN|HGNC=25179|UniProtKB=Q96CM4 Q96CM4 NXNL1 PTHR47109:SF1 NUCLEOREDOXIN-LIKE PROTEIN 1 NUCLEOREDOXIN-LIKE PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176 HUMAN|HGNC=1726|UniProtKB=P30305 P30305 CDC25B PTHR10828:SF48 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 M-PHASE INDUCER PHOSPHATASE 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;meiotic cell cycle process#GO:1903046;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;positive regulation of biological process#GO:0048518;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle phase transition#GO:1901990;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;reproduction#GO:0000003;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 HUMAN|HGNC=1910|UniProtKB=Q13111 Q13111 CHAF1A PTHR15272:SF0 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=3814|UniProtKB=O75593 O75593 FOXH1 PTHR47316:SF1 FORKHEAD BOX PROTEIN H1 FORKHEAD BOX PROTEIN H1 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 HUMAN|HGNC=8605|UniProtKB=Q86W56 Q86W56 PARG PTHR12837:SF0 POLY ADP-RIBOSE GLYCOHYDROLASE POLY(ADP-RIBOSE) GLYCOHYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;regulation of protein modification process#GO:0031399;regulation of response to DNA damage stimulus#GO:2001020;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of histone modification#GO:0031056;regulation of DNA repair#GO:0006282;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;nitrogen compound metabolic process#GO:0006807;regulation of chromatin organization#GO:1902275;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;covalent chromatin modification#GO:0016569;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;nucleobase-containing small molecule metabolic process#GO:0055086;regulation of cellular metabolic process#GO:0031323;small molecule metabolic process#GO:0044281;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 glycosidase#PC00110 HUMAN|HGNC=26565|UniProtKB=Q8WW33 Q8WW33 GTSF1 PTHR21402:SF9 UNCHARACTERIZED GAMETOCYTE-SPECIFIC FACTOR 1 HUMAN|HGNC=14745|UniProtKB=Q8NGD3 Q8NGD3 OR4K5 PTHR48002:SF56 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K5 transmembrane signal receptor#PC00197 HUMAN|HGNC=17755|UniProtKB=Q96RJ3 Q96RJ3 TNFRSF13C PTHR20437:SF2 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 13/17 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13C regulation of cell-cell adhesion#GO:0022407;biological adhesion#GO:0022610;positive regulation of cell population proliferation#GO:0008284;B cell proliferation#GO:0042100;positive regulation of T cell proliferation#GO:0042102;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;leukocyte cell-cell adhesion#GO:0007159;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;T cell proliferation#GO:0042098;leukocyte proliferation#GO:0070661;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of immune system process#GO:0002682;B cell activation#GO:0042113;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;regulation of lymphocyte activation#GO:0051249;mononuclear cell proliferation#GO:0032943;regulation of cell population proliferation#GO:0042127;lymphocyte activation#GO:0046649;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cell adhesion#GO:0007155;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of T cell proliferation#GO:0042129;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;regulation of leukocyte proliferation#GO:0070663;positive regulation of cell adhesion#GO:0045785;positive regulation of cell activation#GO:0050867;positive regulation of cell-cell adhesion#GO:0022409;regulation of B cell proliferation#GO:0030888 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=28749|UniProtKB=Q86WX3 Q86WX3 RPS19BP1 PTHR31454:SF2 ACTIVE REGULATOR OF SIRT1 ACTIVE REGULATOR OF SIRT1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5203|UniProtKB=O75506 O75506 HSBP1 PTHR19424:SF3 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17619|UniProtKB=Q9NXR1 Q9NXR1 NDE1 PTHR10921:SF2 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 vesicle transport along microtubule#GO:0047496;establishment or maintenance of cell polarity#GO:0007163;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;nuclear division#GO:0000280;transport#GO:0006810;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;centrosome cycle#GO:0007098;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;establishment of chromosome localization#GO:0051303;vesicle localization#GO:0051648;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;establishment of spindle localization#GO:0051293;transport along microtubule#GO:0010970;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;establishment of mitotic spindle orientation#GO:0000132;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;movement of cell or subcellular component#GO:0006928;centrosome localization#GO:0051642;protein polymerization#GO:0051258;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular transport#GO:0046907;chromosome localization#GO:0050000;cell migration#GO:0016477;locomotion#GO:0040011;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;kinetochore#GO:0000776;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856 HUMAN|HGNC=23406|UniProtKB=Q9UPQ8 Q9UPQ8 DOLK PTHR13205:SF15 TRANSMEMBRANE PROTEIN 15-RELATED DOLICHOL KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=9861|UniProtKB=P10114 P10114 RAP2A PTHR24070:SF221 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 regulation of cellular component movement#GO:0051270;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;Ras protein signal transduction#GO:0007265;regulation of localization#GO:0032879;localization of cell#GO:0051674;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of cell motility#GO:2000146;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 HUMAN|HGNC=18590|UniProtKB=Q9NST1 Q9NST1 PNPLA3 PTHR12406:SF22 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE PNPLA3 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;chemical homeostasis#GO:0048878;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 phospholipase#PC00186 HUMAN|HGNC=18326|UniProtKB=Q96QA6 Q96QA6 YPEL2 PTHR13848:SF3 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 2 HUMAN|HGNC=14510|UniProtKB=Q96EL2 Q96EL2 MRPS24 PTHR21244:SF1 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S24 28S RIBOSOMAL PROTEIN S24, MITOCHONDRIAL cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202 HUMAN|HGNC=14284|UniProtKB=Q96PG1 Q96PG1 MS4A4E PTHR23320:SF128 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4E-RELATED transporter#PC00227 HUMAN|HGNC=16411|UniProtKB=Q8WV93 Q8WV93 AFG1L PTHR12169:SF6 ATPASE N2B AFG1-LIKE ATPASE hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|Ensembl=ENSG00000278803|UniProtKB=A0A494C071 A0A494C071 ENSG00000278803 PTHR31333:SF2 PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3 FAMILY MEMBER DNA SEGMENT, CHR X, BAYLOR 18-RELATED DNA metabolism protein#PC00009 HUMAN|HGNC=16912|UniProtKB=Q92979 Q92979 EMG1 PTHR12636:SF5 NEP1/MRA1 RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1 catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;rRNA binding#GO:0019843;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684 methyltransferase#PC00155 HUMAN|HGNC=26555|UniProtKB=Q3SY00 Q3SY00 TSGA10IP PTHR21501:SF5 UNCHARACTERIZED TESTIS-SPECIFIC PROTEIN 10-INTERACTING PROTEIN cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 9+0 non-motile cilium#GO:0097731;microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;neuron projection#GO:0043005;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=590|UniProtKB=Q13490 Q13490 BIRC2 PTHR10044:SF173 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 2 cysteine-type peptidase activity#GO:0008234;peptidase inhibitor activity#GO:0030414;ubiquitin-protein transferase activity#GO:0004842;protease binding#GO:0002020;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;transferase activity#GO:0016740;cysteine-type endopeptidase activity#GO:0004197;ubiquitin protein ligase activity#GO:0061630;hydrolase activity#GO:0016787;ubiquitin-like protein ligase activity#GO:0061659;cysteine-type endopeptidase inhibitor activity#GO:0004869;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;spindle organization#GO:0007051;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;negative regulation of endopeptidase activity#GO:0010951;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043154;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;mitotic spindle organization#GO:0007052;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;protein processing#GO:0016485;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;mitotic spindle assembly#GO:0090307;cell death#GO:0008219;mitotic nuclear division#GO:0140014;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;microtubule-based process#GO:0007017;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell cycle#GO:0007049;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 protease inhibitor#PC00191 CCKR signaling map#P06959>BIRC2#G07278;Apoptosis signaling pathway#P00006>c-IAP1,2#P00264 HUMAN|HGNC=8149|UniProtKB=O14841 O14841 OPLAH PTHR11365:SF2 5-OXOPROLINASE RELATED 5-OXOPROLINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 HUMAN|HGNC=1377|UniProtKB=P35218 P35218 CA5A PTHR18952:SF89 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 5A, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|Ensembl=ENSG00000277531|UniProtKB=A0A1B0GUJ8 A0A1B0GUJ8 PNMA8C PTHR23095:SF43 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 8C HUMAN|HGNC=4274|UniProtKB=P17302 P17302 GJA1 PTHR11984:SF33 CONNEXIN GAP JUNCTION ALPHA-1 PROTEIN gap junction#PC00105 HUMAN|HGNC=7686|UniProtKB=O95167 O95167 NDUFA3 PTHR15221:SF0 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 3 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 3 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 dehydrogenase#PC00092 HUMAN|HGNC=18122|UniProtKB=Q9H6I2 Q9H6I2 SOX17 PTHR10270:SF216 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-17 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;positive regulation of transcription, DNA-templated#GO:0045893;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=18666|UniProtKB=Q96LT9 Q96LT9 RNPC3 PTHR16105:SF4 UNCHARACTERIZED RNA-BINDING REGION-CONTAINING PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;snRNA binding#GO:0017069;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U12-type spliceosomal complex#GO:0005689 HUMAN|HGNC=3230|UniProtKB=Q9NYQ7 Q9NYQ7 CELSR3 PTHR24026:SF38 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 3 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=26279|UniProtKB=Q8TAW3 Q8TAW3 ZNF671 PTHR24390:SF44 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 671 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=24489|UniProtKB=Q8ND56 Q8ND56 LSM14A PTHR13586:SF2 SCD6 PROTEIN-RELATED PROTEIN LSM14 HOMOLOG A nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoplasmic mRNA processing body assembly#GO:0033962;cellular process#GO:0009987 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 HUMAN|HGNC=10765|UniProtKB=Q15459 Q15459 SF3A1 PTHR15316:SF1 SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED SPLICING FACTOR 3A SUBUNIT 1 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=33204|UniProtKB=A8MVS1 A8MVS1 ZNF705F PTHR24381:SF303 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 705A-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28087|UniProtKB=Q8NCT1 Q8NCT1 ARRDC4 PTHR11188:SF16 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 4 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 HUMAN|HGNC=7032|UniProtKB=P55081 P55081 MFAP1 PTHR15327:SF0 MICROFIBRIL-ASSOCIATED PROTEIN MICROFIBRILLAR-ASSOCIATED PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 extracellular matrix protein#PC00102 HUMAN|HGNC=11336|UniProtKB=Q16385 Q16385 SSX2 PTHR14112:SF1 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=24045|UniProtKB=Q8NFR3 Q8NFR3 SPTSSB PTHR28612:SF1 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B protein modifying enzyme#PC00260 HUMAN|HGNC=30632|UniProtKB=O94864 O94864 SUPT7L PTHR28598:SF1 STAGA COMPLEX 65 SUBUNIT GAMMA STAGA COMPLEX 65 SUBUNIT GAMMA transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;N-acyltransferase activity#GO:0016410 histone H3 acetylation#GO:0043966;peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=3051|UniProtKB=Q99576 Q99576 TSC22D3 PTHR12348:SF24 TSC22 TSC22 DOMAIN FAMILY PROTEIN 3 HUMAN|HGNC=9461|UniProtKB=P41219 P41219 PRPH PTHR45652:SF14 GLIAL FIBRILLARY ACIDIC PROTEIN PERIPHERIN HUMAN|HGNC=11926|UniProtKB=O14788 O14788 TNFSF11 PTHR11471:SF3 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 HUMAN|GeneID=100506127|UniProtKB=Q3ZCU0 Q3ZCU0 GVQW3 PTHR12138:SF125 PRIMATE-EXPANDED PROTEIN FAMILY PROTEIN GVQW3 HUMAN|HGNC=12295|UniProtKB=Q99603 Q99603 TRGV9 PTHR19256:SF44 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 9 external side of plasma membrane#GO:0009897;leaflet of membrane bilayer#GO:0097478;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=25724|UniProtKB=Q9H9V9 Q9H9V9 JMJD4 PTHR12480:SF6 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4 protein modifying enzyme#PC00260 HUMAN|HGNC=26452|UniProtKB=Q5VSG8 Q5VSG8 MANEAL PTHR13572:SF2 ENDO-ALPHA-1,2-MANNOSIDASE GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=49420|UniProtKB=E9PI22 E9PI22 PRR23D1 PTHR31813:SF3 PROLINE-RICH PROTEIN 23B PROLINE-RICH PROTEIN 23D1-RELATED HUMAN|HGNC=14669|UniProtKB=P81605 P81605 DCD PTHR40711:SF1 DERMCIDIN-RELATED DERMCIDIN cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=28462|UniProtKB=Q9H6F2 Q9H6F2 TMEM38A PTHR12454:SF3 TRIMERIC INTRACELLULAR CATION CHANNEL TRIMERIC INTRACELLULAR CATION CHANNEL TYPE A ion channel#PC00133 HUMAN|HGNC=15935|UniProtKB=Q9H4I2 Q9H4I2 ZHX3 PTHR15467:SF6 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=5607|UniProtKB=A0A0A0MS15 A0A0A0MS15 IGHV3-49 PTHR23266:SF246 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-49 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=6940|UniProtKB=P10911 P10911 MCF2 PTHR22826:SF146 RHO GUANINE EXCHANGE FACTOR-RELATED PROTO-ONCOGENE DBL guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=363|UniProtKB=P27144 P27144 AK4 PTHR23359:SF58 NUCLEOTIDE KINASE ADENYLATE KINASE 4, MITOCHONDRIAL nucleoside diphosphate kinase activity#GO:0004550;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;adenylate kinase activity#GO:0004017;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;nucleoside diphosphate metabolic process#GO:0009132;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 HUMAN|HGNC=13169|UniProtKB=P35789 P35789 ZNF93 PTHR24377:SF811 IP01015P-RELATED ZINC FINGER PROTEIN 93 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=9680|UniProtKB=Q15256 Q15256 PTPRR PTHR46198:SF2 PROTEIN-TYROSINE-PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE R HUMAN|HGNC=13509|UniProtKB=Q9NQS1 Q9NQS1 AVEN PTHR16524:SF2 CELL DEATH REGULATOR AVEN CELL DEATH REGULATOR AVEN negative regulation of biological process#GO:0048519;mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;negative regulation of cellular process#GO:0048523;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839 HUMAN|HGNC=7997|UniProtKB=Q02297 Q02297 NRG1 PTHR11100:SF7 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-1, MEMBRANE-BOUND ISOFORM protein tyrosine kinase activity#GO:0004713;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;receptor regulator activity#GO:0030545;binding#GO:0005488;catalytic activity#GO:0003824;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;signaling receptor binding#GO:0005102;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 HUMAN|HGNC=12770|UniProtKB=O76076 O76076 CCN5 PTHR11348:SF22 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 5 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;biological adhesion#GO:0022610;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;regulation of cell death#GO:0010941;cell death#GO:0008219;biological regulation#GO:0065007;signaling#GO:0023052;negative regulation of cellular process#GO:0048523 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=30747|UniProtKB=P61201 P61201 COPS2 PTHR10678:SF3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 COP9 SIGNALOSOME COMPLEX SUBUNIT 2 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29203|UniProtKB=Q9ULP9 Q9ULP9 TBC1D24 PTHR23353:SF23 RAB-GAP/TBC-RELATED TBC1 DOMAIN FAMILY MEMBER 24 GTPase-activating protein#PC00257 HUMAN|HGNC=30859|UniProtKB=O75643 O75643 SNRNP200 PTHR24075:SF13 SEC63 DOMAIN-CONTAINING U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20569|UniProtKB=Q9UK58 Q9UK58 CCNL1 PTHR10026:SF64 CYCLIN CYCLIN-L1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 kinase activator#PC00138 HUMAN|HGNC=13830|UniProtKB=Q9UHC6 Q9UHC6 CNTNAP2 PTHR15036:SF33 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 2 HUMAN|HGNC=28156|UniProtKB=Q6N075 Q6N075 MFSD5 PTHR23516:SF1 SAM (S-ADENOSYL METHIONINE) TRANSPORTER MOLYBDATE-ANION TRANSPORTER cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=7415|UniProtKB=P03928 P03928 MT-ATP8 PTHR13722:SF0 ATP SYNTHASE PROTEIN 8 ATP SYNTHASE PROTEIN 8 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 HUMAN|HGNC=8747|UniProtKB=Q92824 Q92824 PCSK5 PTHR42884:SF7 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 5 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 HUMAN|HGNC=6244|UniProtKB=Q8WWG9 Q8WWG9 KCNE4 PTHR15282:SF9 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;protein binding#GO:0005515;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 blood circulation#GO:0008015;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of metal ion transport#GO:0010959;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;action potential#GO:0001508;regulation of localization#GO:0032879;regulation of system process#GO:0044057;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;actin-mediated cell contraction#GO:0070252;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;actin filament-based process#GO:0030029;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;monovalent inorganic cation transport#GO:0015672;regulation of multicellular organismal process#GO:0051239;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of heart contraction#GO:0008016;ion transport#GO:0006811;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;regulation of membrane potential#GO:0042391;negative regulation of transport#GO:0051051;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;export from cell#GO:0140352;heart process#GO:0003015;muscle contraction#GO:0006936;negative regulation of molecular function#GO:0044092 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=16391|UniProtKB=Q9H257 Q9H257 CARD9 PTHR14559:SF3 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=11197|UniProtKB=Q9Y651 Q9Y651 SOX21 PTHR10270:SF313 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-21 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=8104|UniProtKB=Q16625 Q16625 OCLN PTHR23288:SF4 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN general transcription factor#PC00259 HUMAN|HGNC=13666|UniProtKB=Q9NRG9 Q9NRG9 AAAS PTHR14494:SF0 ALADIN/ADRACALIN/AAAS ALADIN localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;nuclear transport#GO:0051169 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=10781|UniProtKB=P62995 P62995 TRA2B PTHR48034:SF1 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG BETA positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;positive regulation of RNA metabolic process#GO:0051254;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=18933|UniProtKB=Q3LI67 Q3LI67 KRTAP6-3 PTHR31678:SF6 KERATIN-ASSOCIATED PROTEIN 6-3 KERATIN-ASSOCIATED PROTEIN 6-3 HUMAN|HGNC=24920|UniProtKB=Q96JZ2 Q96JZ2 HSH2D PTHR14388:SF3 T CELL-SPECIFIC ADAPTER PROTEIN TSAD HEMATOPOIETIC SH2 DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 defense/immunity protein#PC00090 HUMAN|HGNC=19849|UniProtKB=Q8N1H7 Q8N1H7 SIX6OS1 PTHR35449:SF1 PROTEIN SIX6OS1 PROTEIN SIX6OS1 DNA repair#GO:0006281;male gamete generation#GO:0048232;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;nitrogen compound metabolic process#GO:0006807;spermatogenesis#GO:0007283;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;multi-organism reproductive process#GO:0044703;meiosis I#GO:0007127;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;nuclear chromosome segregation#GO:0098813;meiosis I cell cycle phase#GO:0098764;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;reproduction#GO:0000003;chromosome organization#GO:0051276;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;DNA double-strand break processing#GO:0000729;cell differentiation#GO:0030154;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;reciprocal meiotic recombination#GO:0007131;cell cycle phase#GO:0022403;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;multicellular organism reproduction#GO:0032504;cellular process#GO:0009987;multi-organism process#GO:0051704;meiotic chromosome segregation#GO:0045132;cell development#GO:0048468;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;organelle fission#GO:0048285;biological phase#GO:0044848;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=23705|UniProtKB=Q9ULM2 Q9ULM2 ZNF490 PTHR24377:SF16 IP01015P-RELATED ZINC FINGER PROTEIN 490 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12651|UniProtKB=P26640 P26640 VARS1 PTHR11946:SF93 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=18817|UniProtKB=Q86YV9 Q86YV9 HPS6 PTHR14696:SF2 HERMANSKY-PUDLAK SYNDROME 6 PROTEIN HERMANSKY-PUDLAK SYNDROME 6 PROTEIN GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 cellular developmental process#GO:0048869;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;developmental process#GO:0032502;pigmentation#GO:0043473;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;lysosome localization#GO:0032418;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;developmental pigmentation#GO:0048066;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;melanocyte differentiation#GO:0030318 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=1485|UniProtKB=A6NHC0 A6NHC0 CAPN8 PTHR10183:SF374 CALPAIN CALPAIN-8 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=560|UniProtKB=P56377 P56377 AP1S2 PTHR11753:SF45 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 HUMAN|HGNC=9669|UniProtKB=P23469 P23469 PTPRE PTHR19134:SF499 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE EPSILON hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=13023|UniProtKB=P17027 P17027 ZNF23 PTHR24377:SF180 IP01015P-RELATED ZINC FINGER PROTEIN 23 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=30598|UniProtKB=Q9NRH2 Q9NRH2 SNRK PTHR24343:SF181 SERINE/THREONINE KINASE SNF-RELATED SERINE/THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 p53 pathway by glucose deprivation#P04397>AMPK#P04639 HUMAN|HGNC=19872|UniProtKB=Q8NFZ6 Q8NFZ6 VN1R2 PTHR24062:SF178 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 2 transmembrane signal receptor#PC00197 HUMAN|HGNC=21302|UniProtKB=Q693B1 Q693B1 KCTD11 PTHR14499:SF7 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD11 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17192|UniProtKB=P58753 P58753 TIRAP PTHR22662:SF0 TIRAP TOLL/INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN Toll receptor signaling pathway#P00054>TIRAP#P01350 HUMAN|HGNC=11044|UniProtKB=P48066 P48066 SLC6A11 PTHR11616:SF124 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;neurotransmitter binding#GO:0042165;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=449|UniProtKB=O95076 O95076 ALX3 PTHR24329:SF340 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARISTALESS-LIKE 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=23706|UniProtKB=Q8N8L2 Q8N8L2 ZNF491 PTHR24381:SF244 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 20-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11817|UniProtKB=O60220 O60220 TIMM8A PTHR19338:SF6 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 13 HOMOLOG MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8 A HUMAN|HGNC=16487|UniProtKB=Q9NPF8 Q9NPF8 ADAP2 PTHR46021:SF6 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 2 intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=12471|UniProtKB=P41226 P41226 UBA7 PTHR10953:SF143 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 7 ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490;Ubiquitin proteasome pathway#P00060>E1#P01492 HUMAN|HGNC=377|UniProtKB=Q9P0M2 Q9P0M2 AKAP7 PTHR15934:SF6 RNA 2',3'-CYCLIC PHOSPHODIESTERASE A-KINASE ANCHOR PROTEIN 7 ISOFORM GAMMA protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;binding#GO:0005488 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA processing factor#PC00147 HUMAN|HGNC=17259|UniProtKB=Q9Y4Z0 Q9Y4Z0 LSM4 PTHR23338:SF16 SMALL NUCLEAR RIBONUCLEOPROTEIN SM U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM4 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;cytoplasmic mRNA processing body assembly#GO:0033962;RNA splicing, via transesterification reactions#GO:0000375 supramolecular complex#GO:0099080;U6 snRNP#GO:0005688;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;Lsm2-8 complex#GO:0120115;intracellular#GO:0005622;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=10493|UniProtKB=P33764 P33764 S100A3 PTHR11639:SF12 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=28672|UniProtKB=Q9BQA9 Q9BQA9 CYBC1 PTHR31837:SF3 CYTOCHROME B-245 CHAPERONE 1 CYTOCHROME B-245 CHAPERONE 1 chaperone#PC00072 HUMAN|HGNC=1693|UniProtKB=P34810 P34810 CD68 PTHR11506:SF2 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN MACROSIALIN localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;cellular protein localization#GO:0034613;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=28240|UniProtKB=Q96D96 Q96D96 HVCN1 PTHR46480:SF1 F20B24.22 VOLTAGE-GATED HYDROGEN CHANNEL 1 HUMAN|HGNC=23690|UniProtKB=Q8TAX9 Q8TAX9 GSDMB PTHR16399:SF20 GASDERMIN GASDERMIN-B phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;defense response#GO:0006952 HUMAN|HGNC=19966|UniProtKB=Q9P2D8 Q9P2D8 UNC79 PTHR21696:SF2 UNCHARACTERIZED PROTEIN UNC-79 HOMOLOG HUMAN|HGNC=6801|UniProtKB=P43357 P43357 MAGEA3 PTHR11736:SF60 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 3-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=1390|UniProtKB=Q13936 Q13936 CACNA1C PTHR45628:SF10 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1C calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812;calcium ion transport#GO:0006816 voltage-gated ion channel#PC00241 Nicotine pharmacodynamics pathway#P06587>CACNA#P06600;Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411 HUMAN|HGNC=20349|UniProtKB=Q63HM2 Q63HM2 PCNX4 PTHR12372:SF6 PECANEX PECANEX-LIKE PROTEIN 4 HUMAN|HGNC=7650|UniProtKB=P41271 P41271 NBL1 PTHR15283:SF5 GREMLIN 1 NEUROBLASTOMA SUPPRESSOR OF TUMORIGENICITY 1 receptor regulator activity#GO:0030545;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;animal organ development#GO:0048513;negative regulation of cellular response to growth factor stimulus#GO:0090288;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;system development#GO:0048731;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=27814|UniProtKB=A6NGR9 A6NGR9 MROH6 PTHR23120:SF40 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 6 HUMAN|HGNC=8820|UniProtKB=P01213 P01213 PDYN PTHR11438:SF4 PROENKEPHALIN PROENKEPHALIN-B protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;axon terminus#GO:0043679;cell body#GO:0044297;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cell projection#GO:0042995;plasma membrane#GO:0005886 neuropeptide#PC00162 Enkephalin release#P05913>Enkephalin#P05976;Opioid prodynorphin pathway#P05916>dynorphin#P06003;Opioid proenkephalin pathway#P05915>leu-Enkephalin#P05989;Opioid prodynorphin pathway#P05916>preprodynorphin#G06047;Enkephalin release#P05913>preproenkephalin mRNA#G06046;Opioid proenkephalin pathway#P05915>peptide F#P05987;Opioid proenkephalin pathway#P05915>Enkephalin#P05991;Opioid proenkephalin pathway#P05915>proenkephalin#P05995;Opioid prodynorphin pathway#P05916>prodynorphin#P05997;Opioid prodynorphin pathway#P05916>preprodynorphin#G06049;Enkephalin release#P05913>preproenkephalin#G06045;Opioid proenkephalin pathway#P05915>met-Enkephalin#P05992;Opioid proenkephalin pathway#P05915>peptide E#P05988 HUMAN|HGNC=33188|UniProtKB=Q6UX39 Q6UX39 AMTN PTHR36858:SF1 AMELOTIN AMELOTIN biomineralization#GO:0110148;regulation of multicellular organismal process#GO:0051239;odontogenesis of dentin-containing tooth#GO:0042475;regulation of anatomical structure morphogenesis#GO:0022603;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of multicellular organismal development#GO:2000026;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of developmental process#GO:0051094;tissue development#GO:0009888;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;biomineral tissue development#GO:0031214;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165 HUMAN|HGNC=12222|UniProtKB=A0A597 A0A597 TRBV5-5 PTHR23268:SF6 T-CELL RECEPTOR BETA CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|Gene=YC018_HUMAN|UniProtKB=Q1RN00 Q1RN00 - PTHR40143:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED HUMAN|HGNC=9036|UniProtKB=P0C869 P0C869 PLA2G4B PTHR10728:SF32 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 BETA hydrolase activity, acting on ester bonds#GO:0016788;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;phospholipid binding#GO:0005543;carboxylic ester hydrolase activity#GO:0052689;cation binding#GO:0043169;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;hydrolase activity#GO:0016787;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phospholipase#PC00186 Oxidative stress response#P00046>cPLA2#P01134;Angiogenesis#P00005>PLA2#P00227;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLA2#P00855;VEGF signaling pathway#P00056>cPLA2#P01409;Angiogenesis#P00005>cPLA2#P00251 HUMAN|HGNC=25292|UniProtKB=Q9H0M5 Q9H0M5 ZNF700 PTHR24379:SF40 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 700 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26914|UniProtKB=Q8N0Z8 Q8N0Z8 PUSL1 PTHR11142:SF0 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE SYNTHASE-LIKE 1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 HUMAN|HGNC=23594|UniProtKB=Q709C8 Q709C8 VPS13C PTHR16166:SF125 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13C cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein localization to Golgi apparatus#GO:0034067;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;maintenance of location#GO:0051235;organelle organization#GO:0006996;maintenance of location in cell#GO:0051651;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898 membrane traffic protein#PC00150 HUMAN|HGNC=15391|UniProtKB=Q8NG97 Q8NG97 OR2Z1 PTHR26453:SF96 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2Z1 transmembrane signal receptor#PC00197 HUMAN|HGNC=6156|UniProtKB=P05106 P05106 ITGB3 PTHR10082:SF25 INTEGRIN BETA SUBUNIT INTEGRIN BETA-3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;biological adhesion#GO:0022610;localization of cell#GO:0051674;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052 membrane protein complex#GO:0098796;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;focal adhesion#GO:0005925;integral component of plasma membrane#GO:0005887;cell-substrate junction#GO:0030055;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 integrin#PC00126 Blood coagulation#P00011>GP IIIa#P00458;Integrin signalling pathway#P00034>Integrin beta#P00931 HUMAN|HGNC=15952|UniProtKB=Q9NQ03 Q9NQ03 SCRT2 PTHR24388:SF48 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR SCRATCH 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=19174|UniProtKB=Q96MX0 Q96MX0 CMTM3 PTHR22776:SF3 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 3 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=14674|UniProtKB=Q96QU1 Q96QU1 PCDH15 PTHR24028:SF11 CADHERIN-87A PROTOCADHERIN-15 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=6482|UniProtKB=P24043 P24043 LAMA2 PTHR10574:SF291 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-2 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=19201|UniProtKB=A6NC42 A6NC42 DPPA5 PTHR31368:SF4 DEVELOPMENT PLURPOTENCY-ASSOCIATED PROTEIN 1/5 FAMILY MEMBER DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED 5 PROTEIN nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=18151|UniProtKB=Q9NPJ8 Q9NPJ8 NXT2 PTHR12612:SF1 NUCLEAR TRANSPORT FACTOR 2 NTF2-RELATED EXPORT PROTEIN 2 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear pore central transport channel#GO:0044613;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=2418|UniProtKB=Q14894 Q14894 CRYM PTHR13812:SF19 KETIMINE REDUCTASE MU-CRYSTALLIN KETIMINE REDUCTASE MU-CRYSTALLIN reductase#PC00198 HUMAN|HGNC=18076|UniProtKB=Q66PJ3 Q66PJ3 ARL6IP4 PTHR13595:SF1 ARL6IP4 PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 4 HUMAN|HGNC=1401|UniProtKB=Q02641 Q02641 CACNB1 PTHR11824:SF17 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;synaptic signaling#GO:0099536;divalent inorganic cation transport#GO:0072511;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;signaling#GO:0023052;cell-cell signaling#GO:0007267;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;regulation of calcium ion transport#GO:0051924;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;neuromuscular junction development#GO:0007528;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of ion transport#GO:0043269 membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411 HUMAN|HGNC=11629|UniProtKB=Q9Y242 Q9Y242 TCF19 PTHR15464:SF1 TRANSCRIPTION FACTOR 19 TRANSCRIPTION FACTOR 19 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=19143|UniProtKB=Q8NFA0 Q8NFA0 USP32 PTHR21646:SF76 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 32 cysteine protease#PC00081 HUMAN|HGNC=23837|UniProtKB=Q32M45 Q32M45 ANO4 PTHR12308:SF28 NGEP-RELATED ANOCTAMIN-4 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;inorganic anion transport#GO:0015698;anion transmembrane transport#GO:0098656 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=16655|UniProtKB=Q86TS9 Q86TS9 MRPL52 PTHR34090:SF1 39S RIBOSOMAL PROTEIN L52, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L52, MITOCHONDRIAL cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=21098|UniProtKB=Q8IWP9 Q8IWP9 CCDC28A PTHR13400:SF3 CHEMOKINE C-C MOTIF RECEPTOR 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 28A transmembrane signal receptor#PC00197 HUMAN|HGNC=27371|UniProtKB=Q5SVS4 Q5SVS4 SLC25A30 PTHR45618:SF11 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED KIDNEY MITOCHONDRIAL CARRIER PROTEIN 1 secondary carrier transporter#PC00258 HUMAN|HGNC=25274|UniProtKB=Q53FE4 Q53FE4 C4orf17 PTHR33772:SF2 THYMUS, BRAIN AND TESTES-ASSOCIATED RIKEN CDNA 4930579F01 GENE HUMAN|HGNC=23449|UniProtKB=Q5VZR2 Q5VZR2 NUTM2G PTHR22879:SF2 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 2F-RELATED HUMAN|HGNC=8617|UniProtKB=P23760 P23760 PAX3 PTHR45636:SF17 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=4080|UniProtKB=Q16445 Q16445 GABRA6 PTHR18945:SF335 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-6 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;cell junction#GO:0030054;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=17916|UniProtKB=Q8WTX9 Q8WTX9 ZDHHC1 PTHR22883:SF8 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=28373|UniProtKB=Q8TC90 Q8TC90 CCER1 PTHR37337:SF1 COILED-COIL DOMAIN-CONTAINING GLUTAMATE-RICH PROTEIN 1 COILED-COIL DOMAIN-CONTAINING GLUTAMATE-RICH PROTEIN 1 HUMAN|HGNC=2899|UniProtKB=Q9Y238 Q9Y238 DLEC1 PTHR46348:SF1 DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 1 DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 1 HUMAN|HGNC=6840|UniProtKB=Q02750 Q02750 MAP2K1 PTHR48013:SF5 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>MEK1-2#P00559;Gonadotropin-releasing hormone receptor pathway#P06664>MEK1/2#P06739;VEGF signaling pathway#P00056>MEK#P01402;T cell activation#P00053>MEK#P01312;Gonadotropin-releasing hormone receptor pathway#P06664>MAP2K1/2#P06794;FGF signaling pathway#P00021>MEK1-2#P00642;B cell activation#P00010>MEK#P00383;Toll receptor signaling pathway#P00054>MKK1#P01369;Ras Pathway#P04393>MEK#P04557;Integrin signalling pathway#P00034>MEK#P00925;PDGF signaling pathway#P00047>MEK#P01162;Integrin signalling pathway#P00034>ERK#P00907;Angiogenesis#P00005>MEK#P00225;CCKR signaling map#P06959>MAP2K1#P07194;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MEK#P05926;Endothelin signaling pathway#P00019>MEK#P00572;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 HUMAN|HGNC=25829|UniProtKB=Q6UWZ7 Q6UWZ7 ABRAXAS1 PTHR31728:SF2 ABRAXAS FAMILY MEMBER BRCA1-A COMPLEX SUBUNIT ABRAXAS 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;macromolecule modification#GO:0043412;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;protein K63-linked deubiquitination#GO:0070536;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;mitotic spindle assembly#GO:0090307;proteolysis#GO:0006508;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic nuclear division#GO:0140014;spindle organization#GO:0007051;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;cell cycle#GO:0007049;organelle fission#GO:0048285 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8624|UniProtKB=Q6ZW49 Q6ZW49 PAXIP1 PTHR23196:SF1 PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN PAX-INTERACTING PROTEIN 1 HUMAN|HGNC=7843|UniProtKB=P28336 P28336 NMBR PTHR45695:SF8 LEUCOKININ RECEPTOR-RELATED NEUROMEDIN-B RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=25563|UniProtKB=Q8WU58 Q8WU58 FAM222B PTHR16070:SF1 UNCHARACTERIZED PROTEIN FAM222B HUMAN|HGNC=14624|UniProtKB=Q99618 Q99618 CDCA3 PTHR34756:SF1 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 3 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 3 HUMAN|HGNC=9107|UniProtKB=Q9Y4D7 Q9Y4D7 PLXND1 PTHR22625:SF7 PLEXIN PLEXIN-D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of GTPase activity#GO:0043087;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cell adhesion#GO:0007155;endothelial cell migration#GO:0043542;regulation of neuron differentiation#GO:0045664;negative regulation of cell adhesion#GO:0007162;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;positive regulation of neuron projection development#GO:0010976;locomotion#GO:0040011;taxis#GO:0042330;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of cell projection organization#GO:0031346;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;biological adhesion#GO:0022610;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of cell adhesion#GO:0030155;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;positive regulation of neuron differentiation#GO:0045666;cellular response to stimulus#GO:0051716;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;cell migration#GO:0016477 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=33983|UniProtKB=P0CG36 P0CG36 CFC1B PTHR14949:SF25 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 CRYPTIC FAMILY PROTEIN 1B-RELATED protein binding#GO:0005515;binding#GO:0005488;receptor serine/threonine kinase binding#GO:0033612;signaling receptor binding#GO:0005102 specification of symmetry#GO:0009799;cellular response to stimulus#GO:0051716;heart development#GO:0007507;signal transduction#GO:0007165;circulatory system development#GO:0072359;enzyme linked receptor protein signaling pathway#GO:0007167;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;determination of bilateral symmetry#GO:0009855;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;determination of left/right symmetry#GO:0007368;pattern specification process#GO:0007389;signaling#GO:0023052 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=9889|UniProtKB=Q7Z6E9 Q7Z6E9 RBBP6 PTHR15439:SF0 RETINOBLASTOMA-BINDING PROTEIN 6 E3 UBIQUITIN-PROTEIN LIGASE RBBP6 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=4078|UniProtKB=P48169 P48169 GABRA4 PTHR18945:SF393 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-4 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;cell junction#GO:0030054;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=28654|UniProtKB=Q8IYP9 Q8IYP9 ZDHHC23 PTHR22883:SF99 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC23 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=28900|UniProtKB=Q9NP80 Q9NP80 PNPLA8 PTHR24185:SF1 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phospholipase#PC00186 HUMAN|HGNC=10413|UniProtKB=P62851 P62851 RPS25 PTHR12850:SF18 40S RIBOSOMAL PROTEIN S25 40S RIBOSOMAL PROTEIN S25 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=9142|UniProtKB=P54821 P54821 PRRX1 PTHR46385:SF1 PAIRED MESODERM HOMEOBOX PROTEIN 1-RELATED PAIRED MESODERM HOMEOBOX PROTEIN 1 HUMAN|HGNC=10662|UniProtKB=O00560 O00560 SDCBP PTHR12345:SF10 SYNTENIN RELATED SYNTENIN-1 carbohydrate derivative binding#GO:0097367;protein binding#GO:0005515;binding#GO:0005488 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;regulation of cellular response to transforming growth factor beta stimulus#GO:1903844;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=10737|UniProtKB=Q9P283 Q9P283 SEMA5B PTHR11036:SF39 SEMAPHORIN SEMAPHORIN-5B receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=15328|UniProtKB=Q8NGE9 Q8NGE9 OR9Q2 PTHR48018:SF144 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9Q2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=15167|UniProtKB=Q6IEV9 Q6IEV9 OR4C11 PTHR48002:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C11 transmembrane signal receptor#PC00197 HUMAN|HGNC=19003|UniProtKB=Q96GD3 Q96GD3 SCMH1 PTHR12247:SF68 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SCMH1 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=20704|UniProtKB=Q9BQ90 Q9BQ90 KLHDC3 PTHR46461:SF1 KELCH DOMAIN-CONTAINING PROTEIN 3 KELCH DOMAIN-CONTAINING PROTEIN 3 binding#GO:0005488;chromatin binding#GO:0003682 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=15169|UniProtKB=Q8NGP0 Q8NGP0 OR4C13 PTHR48002:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C13 transmembrane signal receptor#PC00197 HUMAN|HGNC=12515|UniProtKB=P15374 P15374 UCHL3 PTHR10589:SF24 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L3 hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=11743|UniProtKB=Q92481 Q92481 TFAP2B PTHR10812:SF14 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 general transcription factor#PC00259 HUMAN|HGNC=33914|UniProtKB=P59773 P59773 MINAR2 PTHR31530:SF4 MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 MINAR1 FAMILY MEMBER MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1-LIKE transmembrane signal receptor#PC00197 HUMAN|HGNC=7464|UniProtKB=P49286 P49286 MTNR1B PTHR24228:SF54 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN RECEPTOR TYPE 1B regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 HUMAN|Ensembl=ENSG00000182974|UniProtKB=A0A0X1KG70 A0A0X1KG70 ENSG00000182974 PTHR48002:SF103 OLFACTORY RECEPTOR G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=13004|UniProtKB=Q9UDV6 Q9UDV6 ZNF212 PTHR24390:SF49 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 212 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6050|UniProtKB=P29218 P29218 IMPA1 PTHR20854:SF26 INOSITOL MONOPHOSPHATASE INOSITOL MONOPHOSPHATASE 1 inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;signaling#GO:0023052;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 phosphatase#PC00181 HUMAN|HGNC=17949|UniProtKB=Q5JTD0 Q5JTD0 TJAP1 PTHR28664:SF3 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=3069|UniProtKB=P51452 P51452 DUSP3 PTHR45682:SF1 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 3 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=19627|UniProtKB=A0A2R8YED5 A0A2R8YED5 OR5BS1P PTHR26452:SF805 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=27619|UniProtKB=Q149M9 Q149M9 NWD1 PTHR45013:SF1 NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1 NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1 HUMAN|HGNC=30268|UniProtKB=Q96AX2 Q96AX2 RAB37 PTHR47978:SF35 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-37 HUMAN|HGNC=13187|UniProtKB=P60852 P60852 ZP1 PTHR23343:SF41 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 1 HUMAN|HGNC=17271|UniProtKB=P62070 P62070 RRAS2 PTHR24070:SF396 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN R-RAS2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;EGF receptor signaling pathway#P00018>Ras#P00552 HUMAN|HGNC=14725|UniProtKB=Q6IF00 Q6IF00 OR2T2 PTHR26453:SF18 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T2-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=72|UniProtKB=Q9NUQ8 Q9NUQ8 ABCF3 PTHR19211:SF117 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 translation elongation factor#PC00222 HUMAN|HGNC=10263|UniProtKB=P56715 P56715 RP1 PTHR23005:SF4 RETINITIS PIGMENTOSA 1 PROTEIN NEURONAL MIGRATION PROTEIN DOUBLECORTIN-RELATED microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;sensory system development#GO:0048880;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;anatomical structure development#GO:0048856;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;animal organ development#GO:0048513;developmental process#GO:0032502;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;retina development in camera-type eye#GO:0060041;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;protein localization to organelle#GO:0033365;visual system development#GO:0150063;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cell development#GO:0048468;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;eye development#GO:0001654;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;camera-type eye development#GO:0043010;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=26417|UniProtKB=Q7RTX9 Q7RTX9 SLC16A14 PTHR11360:SF239 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 14 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=24536|UniProtKB=Q6UWI2 Q6UWI2 PARM1 PTHR35453:SF1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;RNA-dependent DNA biosynthetic process#GO:0006278;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=31811|UniProtKB=P0C7V8 P0C7V8 DCAF8L2 PTHR15574:SF42 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 8-LIKE PROTEIN 2 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=8749|UniProtKB=Q00536 Q00536 CDK16 PTHR24056:SF174 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 16 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cell projection organization#GO:0030030;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;organelle membrane fusion#GO:0090174;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;nucleobase-containing compound metabolic process#GO:0006139;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;secretion#GO:0046903;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;organelle fusion#GO:0048284;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cell cycle phase transition#GO:0044770;exocytic process#GO:0140029;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;nucleobase-containing compound biosynthetic process#GO:0034654;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron development#GO:0048666;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;export from cell#GO:0140352;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;vesicle fusion#GO:0006906;neurogenesis#GO:0022008;mitotic cell cycle phase transition#GO:0044772;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cell cycle G1/S phase transition#GO:0044843;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;developmental process#GO:0032502;cell cycle process#GO:0022402;protein modification process#GO:0036211;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;vesicle organization#GO:0016050;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;secretion by cell#GO:0032940;metabolic process#GO:0008152;vesicle fusion to plasma membrane#GO:0099500;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;membrane fusion#GO:0061025;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;regulation of cellular macromolecule biosynthetic process#GO:2000112 presynapse#GO:0098793;synapse#GO:0045202;nucleus#GO:0005634;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=25201|UniProtKB=Q86XT9 Q86XT9 TMEM219 PTHR16002:SF6 TRANSMEMBRANE PROTEIN 248-LIKE INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 3 RECEPTOR HUMAN|HGNC=20344|UniProtKB=Q8N806 Q8N806 UBR7 PTHR13513:SF9 E3 UBIQUITIN-PROTEIN LIGASE UBR7 E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9260|UniProtKB=Q9Y3C6 Q9Y3C6 PPIL1 PTHR45625:SF7 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 1 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=16988|UniProtKB=Q9BRL6 Q9BRL6 SRSF8 PTHR23147:SF14 SERINE/ARGININE RICH SPLICING FACTOR SERINE/ARGININE-RICH SPLICING FACTOR 8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=16852|UniProtKB=O75159 O75159 SOCS5 PTHR10155:SF15 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 5 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phosphorylation#GO:0016310;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 HUMAN|HGNC=21197|UniProtKB=Q7L5A8 Q7L5A8 FA2H PTHR12863:SF1 FATTY ACID HYDROXYLASE FATTY ACID 2-HYDROXYLASE hydroxylase#PC00122 HUMAN|HGNC=16148|UniProtKB=Q9UJA2 Q9UJA2 CRLS1 PTHR14269:SF11 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED CARDIOLIPIN SYNTHASE (CMP-FORMING) lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=25444|UniProtKB=Q8NCD3 Q8NCD3 HJURP PTHR15992:SF5 HOLLIDAY JUNCTION RECOGNITION PROTEIN HOLLIDAY JUNCTION RECOGNITION PROTEIN HUMAN|HGNC=11896|UniProtKB=P21580 P21580 TNFAIP3 PTHR13367:SF3 UBIQUITIN THIOESTERASE TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 3 thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;omega peptidase activity#GO:0008242;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 positive regulation of signal transduction#GO:0009967;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;cytoskeleton organization#GO:0007010;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;cellular component organization#GO:0016043;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;protein modification by small protein removal#GO:0070646;movement of cell or subcellular component#GO:0006928;protein deubiquitination#GO:0016579;locomotion#GO:0040011;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;signaling#GO:0023052;cell-cell signaling#GO:0007267;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;cellular protein catabolic process#GO:0044257;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;cell migration#GO:0016477;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 Toll receptor signaling pathway#P00054>A20#P01348 HUMAN|HGNC=19906|UniProtKB=O00398 O00398 P2RY10 PTHR24232:SF47 G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 10-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=934|UniProtKB=Q9Y5Z0 Q9Y5Z0 BACE2 PTHR47965:SF40 ASPARTYL PROTEASE-RELATED BETA-SECRETASE 2 membrane protein proteolysis#GO:0033619;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein metabolic process#GO:0019538;membrane protein ectodomain proteolysis#GO:0006509;primary metabolic process#GO:0044238;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>BACE-1#P00101;Alzheimer disease-amyloid secretase pathway#P00003>Pro-BACE-1#P00081;Alzheimer disease-presenilin pathway#P00004>BACE-1#P00172;Alzheimer disease-presenilin pathway#P00004>BACE-1 pro-domain#P00178;Alzheimer disease-presenilin pathway#P00004>Pro-BACE-1#P00162;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1 pro-domain#P00094 HUMAN|HGNC=18565|UniProtKB=Q8TDC0 Q8TDC0 MYOZ3 PTHR15941:SF15 MYOZENIN MYOZENIN-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 supramolecular complex#GO:0099080;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 non-motor actin binding protein#PC00165 HUMAN|HGNC=5012|UniProtKB=O75330 O75330 HMMR PTHR18956:SF6 HYALURONAN MEDIATED MOTILITY RECEPTOR HYALURONAN MEDIATED MOTILITY RECEPTOR HUMAN|HGNC=41525|UniProtKB=P61550 P61550 ERVS71-1 PTHR10424:SF41 VIRAL ENVELOPE PROTEIN ENDOGENOUS RETROVIRUS GROUP S71 MEMBER 1 ENV POLYPROTEIN viral or transposable element protein#PC00237 HUMAN|HGNC=11253|UniProtKB=Q9BUD6 Q9BUD6 SPON2 PTHR11311:SF15 SPONDIN SPONDIN-2 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cell adhesion molecule#PC00069 HUMAN|HGNC=18294|UniProtKB=Q9BT22 Q9BT22 ALG1 PTHR13036:SF1 BETA1,4 MANNOSYLTRANSFERASE CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=2957|UniProtKB=P49184 P49184 DNASE1L1 PTHR11371:SF28 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1-LIKE 1 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;endodeoxyribonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;deoxyribonuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;DNA catabolic process, endonucleolytic#GO:0000737;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=13232|UniProtKB=Q8NHQ8 Q8NHQ8 RASSF8 PTHR15286:SF9 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 8 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11597|UniProtKB=Q13207 Q13207 TBX2 PTHR11267:SF82 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell fate commitment#GO:0045165;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=10980|UniProtKB=Q9UBX3 Q9UBX3 SLC25A10 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;succinate transmembrane transporter activity#GO:0015141;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;dicarboxylic acid transmembrane transporter activity#GO:0005310;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;organic substance transport#GO:0071702;establishment of localization#GO:0051234;anion transport#GO:0006820;C4-dicarboxylate transport#GO:0015740;organic acid transmembrane transport#GO:1903825;inorganic anion transport#GO:0015698 secondary carrier transporter#PC00258 HUMAN|HGNC=29317|UniProtKB=Q9HCJ2 Q9HCJ2 LRRC4C PTHR24369:SF8 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 3-RELATED HUMAN|HGNC=12194|UniProtKB=A0A075B6N1 A0A075B6N1 TRBV19 PTHR23268:SF28 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 19 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 T cell activation#P00053>TCR Beta#P01299 HUMAN|HGNC=690|UniProtKB=O95376 O95376 ARIH2 PTHR11685:SF210 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH2 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9369|UniProtKB=P49642 P49642 PRIM1 PTHR10536:SF0 DNA PRIMASE SMALL SUBUNIT DNA PRIMASE SMALL SUBUNIT catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;DNA biosynthetic process#GO:0071897;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 primase#PC00189 DNA replication#P00017>Primase#P00528 HUMAN|HGNC=11189|UniProtKB=O00570 O00570 SOX1 PTHR10270:SF40 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=26679|UniProtKB=Q5VTT5 Q5VTT5 MYOM3 PTHR13817:SF89 TITIN MYOMESIN-3 HUMAN|HGNC=25370|UniProtKB=Q8IV38 Q8IV38 ANKMY2 PTHR24150:SF8 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=25577|UniProtKB=Q9HCJ3 Q9HCJ3 RAVER2 PTHR23189:SF6 RNA RECOGNITION MOTIF-CONTAINING RIBONUCLEOPROTEIN PTB-BINDING 2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=15562|UniProtKB=Q9UHA7 Q9UHA7 IL36A PTHR10078:SF25 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-36 ALPHA receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to lipopolysaccharide#GO:0071222;gene expression#GO:0010467;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of metabolic process#GO:0009893;response to biotic stimulus#GO:0009607;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 interleukin superfamily#PC00128 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 HUMAN|HGNC=32962|UniProtKB=P0C7U3 P0C7U3 ZDHHC11B PTHR22883:SF22 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC11-RELATED transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=8569|UniProtKB=P29122 P29122 PCSK6 PTHR42884:SF8 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 6 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;extracellular matrix#GO:0031012;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;cell surface#GO:0009986;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;collagen-containing extracellular matrix#GO:0062023;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 HUMAN|HGNC=18955|UniProtKB=P57105 P57105 SYNJ2BP PTHR23119:SF33 DISCS LARGE DISKS LARGE HOMOLOG 4-RELATED establishment or maintenance of cell polarity#GO:0007163;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;developmental process#GO:0032502;biological adhesion#GO:0022610;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to organelle#GO:0033365;cell-cell signaling#GO:0007267;signaling#GO:0023052;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;neuromuscular junction#GO:0031594;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;basolateral plasma membrane#GO:0016323;ion channel complex#GO:0034702;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Huntington disease#P00029>PSD-95#P00789 HUMAN|HGNC=8356|UniProtKB=O76100 O76100 OR7A10 PTHR48001:SF112 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7A10 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=1083|UniProtKB=Q12982 Q12982 BNIP2 PTHR12112:SF12 BNIP - RELATED BCL2/ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 2 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;phosphorus metabolic process#GO:0006793;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=17788|UniProtKB=Q9HAP6 Q9HAP6 LIN7B PTHR14063:SF7 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG B protein binding#GO:0005515;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;establishment or maintenance of bipolar cell polarity#GO:0061245;export from cell#GO:0140352 membrane protein complex#GO:0098796;synapse#GO:0045202;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070 HUMAN|HGNC=3768|UniProtKB=Q68DA7 Q68DA7 FMN1 PTHR13037:SF11 FORMIN FORMIN-1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=983|UniProtKB=P06276 P06276 BCHE PTHR43918:SF5 ACETYLCHOLINESTERASE CHOLINESTERASE esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 HUMAN|HGNC=19307|UniProtKB=Q7Z5N4 Q7Z5N4 SDK1 PTHR13817:SF55 TITIN PROTEIN SIDEKICK-1 HUMAN|HGNC=14276|UniProtKB=Q9BYD3 Q9BYD3 MRPL4 PTHR10746:SF6 50S RIBOSOMAL PROTEIN L4 39S RIBOSOMAL PROTEIN L4, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202 HUMAN|HGNC=19089|UniProtKB=Q8TAD4 Q8TAD4 SLC30A5 PTHR45755:SF1 FAMILY NOT NAMED ZINC TRANSPORTER 5 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=25631|UniProtKB=Q96MT7 Q96MT7 CFAP44 PTHR13720:SF18 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 44 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;protein localization to cilium#GO:0061512;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;cilium movement#GO:0003341;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503 HUMAN|HGNC=10075|UniProtKB=O43148 O43148 RNMT PTHR12189:SF2 MRNA GUANINE-7- METHYLTRANSFERASE MRNA CAP GUANINE-N7 METHYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 HUMAN|HGNC=9446|UniProtKB=P16471 P16471 PRLR PTHR23036:SF86 CYTOKINE RECEPTOR PROLACTIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PRLR#P06822 HUMAN|HGNC=20466|UniProtKB=Q96SB8 Q96SB8 SMC6 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 DNA metabolism protein#PC00009 HUMAN|HGNC=18546|UniProtKB=Q9UKY3 Q9UKY3 CES1P1 PTHR11559:SF179 CARBOXYLESTERASE LIVER CARBOXYLESTERASE 1-RELATED hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 esterase#PC00097 HUMAN|HGNC=17821|UniProtKB=O00148 O00148 DDX39A PTHR47958:SF10 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX39A catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;RNA metabolic process#GO:0016070;transport#GO:0006810;RNA processing#GO:0006396;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;heterocycle metabolic process#GO:0046483;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;peptide transport#GO:0015833;mRNA transport#GO:0051028;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;mRNA processing#GO:0006397;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA splicing, via transesterification reactions#GO:0000375;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 HUMAN|HGNC=3419|UniProtKB=P42566 P42566 EPS15 PTHR11216:SF54 EH DOMAIN EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=13128|UniProtKB=Q9Y462 Q9Y462 ZNF711 PTHR16515:SF10 PR DOMAIN ZINC FINGER PROTEIN ZINC FINGER PROTEIN 711 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15748|UniProtKB=Q9UKY0 Q9UKY0 PRND PTHR15506:SF0 DOPPEL PRION PRION-LIKE PROTEIN DOPPEL HUMAN|HGNC=23136|UniProtKB=Q9BWG6 Q9BWG6 SCNM1 PTHR32297:SF1 SODIUM CHANNEL MODIFIER 1 SODIUM CHANNEL MODIFIER 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ion channel#PC00133 HUMAN|HGNC=16021|UniProtKB=Q9Y5N5 Q9Y5N5 N6AMT1 PTHR45875:SF3 METHYLTRANSFERASE N6AMT1 METHYLTRANSFERASE N6AMT1 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 methyltransferase#PC00155 HUMAN|HGNC=5247|UniProtKB=Q16082 Q16082 HSPB2 PTHR45640:SF27 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-2 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 HUMAN|HGNC=28953|UniProtKB=Q15040 Q15040 JOSD1 PTHR13291:SF1 JOSEPHIN 1, 2 JOSEPHIN-1 hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081 HUMAN|HGNC=16271|UniProtKB=Q9H4I0 Q9H4I0 RAD21L1 PTHR12585:SF19 SCC1 / RAD21 FAMILY MEMBER DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;double-strand break repair#GO:0006302;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;meiotic sister chromatid segregation#GO:0045144;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;M phase#GO:0000279;sister chromatid cohesion#GO:0007062;chromosome organization involved in meiotic cell cycle#GO:0070192;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;meiosis I cell cycle phase#GO:0098764;cellular response to stimulus#GO:0051716;mitotic sister chromatid cohesion#GO:0007064;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=34386|UniProtKB=Q6UXP3 Q6UXP3 TMEM14EP PTHR12668:SF4 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14C-RELATED localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;transport#GO:0006810 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 HUMAN|HGNC=10827|UniProtKB=O60239 O60239 SH3BP5 PTHR19423:SF1 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5 scaffold/adaptor protein#PC00226 HUMAN|HGNC=37220|UniProtKB=P86481 P86481 PRR20B PTHR38819:SF1 PROLINE-RICH PROTEIN 20A-RELATED PROLINE-RICH PROTEIN 20A-RELATED HUMAN|HGNC=13617|UniProtKB=Q8NCQ5 Q8NCQ5 FBXO15 PTHR46731:SF1 F-BOX ONLY PROTEIN 15 F-BOX ONLY PROTEIN 15 HUMAN|HGNC=7969|UniProtKB=Q14994 Q14994 NR1I3 PTHR24082:SF231 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=1400|UniProtKB=Q9NY47 Q9NY47 CACNA2D2 PTHR10166:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-2 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=33480|UniProtKB=Q4G0S4 Q4G0S4 CYP27C1 PTHR24291:SF9 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 27C1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177 Vitamin D metabolism and pathway#P04396>1alpha-Hydroxylase#P04603 HUMAN|HGNC=33745|UniProtKB=Q6URK8 Q6URK8 TEPP PTHR35348:SF1 TESTIS, PROSTATE AND PLACENTA-EXPRESSED PROTEIN TESTIS, PROSTATE AND PLACENTA-EXPRESSED PROTEIN HUMAN|HGNC=28664|UniProtKB=Q5TAH2 Q5TAH2 SLC9C2 PTHR10110:SF91 SODIUM/HYDROGEN EXCHANGER SODIUM/HYDROGEN EXCHANGER 11 secondary carrier transporter#PC00258 HUMAN|HGNC=13816|UniProtKB=P54707 P54707 ATP12A PTHR43294:SF1 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;potassium ion transport#GO:0006813;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;cellular monovalent inorganic cation homeostasis#GO:0030004;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725;export from cell#GO:0140352 primary active transporter#PC00068 HUMAN|HGNC=17964|UniProtKB=Q8TC12 Q8TC12 RDH11 PTHR24320:SF108 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 11 dehydrogenase#PC00092 HUMAN|HGNC=29323|UniProtKB=Q6ZS81 Q6ZS81 WDFY4 PTHR46108:SF3 BLUE CHEESE WD REPEAT- AND FYVE DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=17521|UniProtKB=Q96PM9 Q96PM9 ZNF385A PTHR23067:SF13 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385A membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=30907|UniProtKB=O60504 O60504 SORBS3 PTHR14167:SF54 SH3 DOMAIN-CONTAINING VINEXIN HUMAN|HGNC=16007|UniProtKB=Q969Q1 Q969Q1 TRIM63 PTHR24103:SF570 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM63 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=18626|UniProtKB=Q9BW83 Q9BW83 IFT27 PTHR47979:SF7 DRAB11-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 27 HOMOLOG HUMAN|HGNC=26261|UniProtKB=Q6UY01 Q6UY01 LRRC31 PTHR24109:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 31 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 31 HUMAN|HGNC=5185|UniProtKB=O00198 O00198 HRK PTHR15056:SF0 ACTIVATOR OF APOPTOSIS HARAKIRI ACTIVATOR OF APOPTOSIS HARAKIRI regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=31042|UniProtKB=Q9C091 Q9C091 GREB1L PTHR15720:SF12 GREB1-RELATED GREB1-LIKE PROTEIN HUMAN|HGNC=24827|UniProtKB=Q8TDS4 Q8TDS4 HCAR2 PTHR46048:SF6 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HUMAN|HGNC=18649|UniProtKB=Q9UBP9 Q9UBP9 GULP1 PTHR11232:SF31 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PTB DOMAIN-CONTAINING ENGULFMENT ADAPTER PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=21076|UniProtKB=Q9Y6G1 Q9Y6G1 TMEM14A PTHR12668:SF11 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14A localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;transport#GO:0006810 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 HUMAN|HGNC=12663|UniProtKB=P19320 P19320 VCAM1 PTHR13771:SF14 INTERCELLULAR ADHESION MOLECULE VASCULAR CELL ADHESION PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=468|UniProtKB=P23109 P23109 AMPD1 PTHR11359:SF1 AMP DEAMINASE AMP DEAMINASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;AMP metabolic process#GO:0046033;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 deaminase#PC00088 HUMAN|HGNC=18239|UniProtKB=Q68EM7 Q68EM7 ARHGAP17 PTHR14130:SF3 3BP-1 RELATED RHOGAP RHO GTPASE-ACTIVATING PROTEIN 17 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;Rac GTPase binding#GO:0048365;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;nucleoside-triphosphatase activity#GO:0017111 vesicle fusion#GO:0006906;signal transduction#GO:0007165;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;regulation of cellular component organization#GO:0051128;regulation of intracellular signal transduction#GO:1902531;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of signal transduction#GO:0009966;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;vesicle organization#GO:0016050;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;intracellular signal transduction#GO:0035556;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;regulation of small GTPase mediated signal transduction#GO:0051056;localization#GO:0051179;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036;regulation of Ras protein signal transduction#GO:0046578;export from cell#GO:0140352 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9470|UniProtKB=O14669 O14669 PRRG2 PTHR24278:SF30 COAGULATION FACTOR TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=6743|UniProtKB=Q14444 Q14444 CAPRIN1 PTHR22922:SF3 GPI-ANCHORED PROTEIN P137 CAPRIN-1 RNA metabolism protein#PC00031 HUMAN|HGNC=11879|UniProtKB=P63313 P63313 TMSB10 PTHR12021:SF10 THYMOSIN BETA THYMOSIN BETA-10 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;cellular protein localization#GO:0034613;protein-containing complex assembly#GO:0065003;regulation of localization#GO:0032879;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;regulation of cellular component movement#GO:0051270;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of cell motility#GO:2000145;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;localization of cell#GO:0051674;actin polymerization or depolymerization#GO:0008154;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|Gene=HV108_HUMAN|UniProtKB=P0DP01 P0DP01 IGHV1-8 PTHR23266:SF282 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-8 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=12544|UniProtKB=P36537 P36537 UGT2B10 PTHR48043:SF86 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2B10-RELATED transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=21269|UniProtKB=P59047 P59047 NLRP5 PTHR45690:SF7 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 5 HUMAN|HGNC=17155|UniProtKB=Q9Y3P9 Q9Y3P9 RABGAP1 PTHR22957:SF439 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN RAB GTPASE-ACTIVATING PROTEIN 1 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=1189|UniProtKB=O95433 O95433 AHSA1 PTHR13009:SF7 HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1 ACTIVATOR OF 90 KDA HEAT SHOCK PROTEIN ATPASE HOMOLOG 1 pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;ATPase activator activity#GO:0001671;enzyme regulator activity#GO:0030234;ATPase activity#GO:0016887 regulation of molecular function#GO:0065009;protein folding#GO:0006457;positive regulation of catalytic activity#GO:0043085;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=29007|UniProtKB=Q14CM0 Q14CM0 FRMPD4 PTHR46221:SF4 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=30576|UniProtKB=Q9BV57 Q9BV57 ADI1 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE 1,2-DIHYDROXY-3-KETO-5-METHYLTHIOPENTENE DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid metabolic process#GO:0006520;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxygenase#PC00177 HUMAN|HGNC=6200|UniProtKB=Q9Y4A0 Q9Y4A0 JRKL PTHR19303:SF16 TRANSPOSON JERKY PROTEIN HOMOLOG-LIKE nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 HUMAN|HGNC=25052|UniProtKB=Q96GV9 Q96GV9 MACIR PTHR31224:SF2 UNC119-BINDING PROTEIN C5ORF30 MACROPHAGE IMMUNOMETABOLISM REGULATOR negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;gene expression#GO:0010467;regulation of localization#GO:0032879;negative regulation of inflammatory response#GO:0050728;inflammatory response#GO:0006954;cytokine production#GO:0001816;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;negative regulation of cell motility#GO:2000146;regulation of gene expression#GO:0010468;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;regulation of cellular component movement#GO:0051270;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;localization of cell#GO:0051674;cell motility#GO:0048870;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;regulation of defense response#GO:0031347;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of response to external stimulus#GO:0032102;multicellular organismal process#GO:0032501;cell migration#GO:0016477;locomotion#GO:0040011;regulation of metabolic process#GO:0019222 HUMAN|HGNC=19770|UniProtKB=Q6ZVZ8 Q6ZVZ8 ASB18 PTHR24118:SF76 POTE ANKYRIN DOMAIN ANKYRIN REPEAT AND SOCS BOX PROTEIN 18 membrane traffic protein#PC00150 HUMAN|HGNC=4536|UniProtKB=P60893 P60893 GPR85 PTHR19268:SF7 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 85-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=1820|UniProtKB=P31997 P31997 CEACAM8 PTHR44337:SF1 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 HUMAN|HGNC=6947|UniProtKB=P33991 P33991 MCM4 PTHR11630:SF66 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM4 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 DNA repair#GO:0006281;cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;nuclear DNA replication#GO:0033260;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;mitotic DNA replication#GO:1902969;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication initiation#GO:0006270;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;DNA duplex unwinding#GO:0032508;mitotic nuclear division#GO:0140014;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;DNA unwinding involved in DNA replication#GO:0006268;pre-replicative complex assembly involved in nuclear cell cycle DNA replication#GO:0006267;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;cell cycle#GO:0007049;organelle fission#GO:0048285;DNA replication#GO:0006260;DNA metabolic process#GO:0006259;DNA strand elongation involved in DNA replication#GO:0006271 protein-containing complex#GO:0032991;nucleus#GO:0005634;MCM core complex#GO:0097373;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=2033|UniProtKB=P78369 P78369 CLDN10 PTHR12002:SF13 CLAUDIN CLAUDIN-10 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=28736|UniProtKB=Q86UF4 Q86UF4 CCDC190 PTHR36871:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 190 COILED-COIL DOMAIN-CONTAINING PROTEIN 190 HUMAN|Gene=SGK223|UniProtKB=Q86YV5 Q86YV5 PRAG1 PTHR22972:SF3 SERINE/THREONINE PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE PRAG1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=34399|UniProtKB=Q6UW78 Q6UW78 UQCC3 PTHR36465:SF1 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 3 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 3 chaperone#PC00072 HUMAN|HGNC=14821|UniProtKB=Q8NG75 Q8NG75 OR5T1 PTHR24248:SF33 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 5T1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|Ensembl=ENSG00000282822|UniProtKB=A0A0J9YW62 A0A0J9YW62 ENSG00000282822 PTHR23266:SF273 IMMUNOGLOBULIN HEAVY CHAIN IGV DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=18633|UniProtKB=Q6PL24 Q6PL24 TMED8 PTHR22973:SF3 LD35087P PROTEIN TMED8 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=30260|UniProtKB=Q9NVS9 Q9NVS9 PNPO PTHR10851:SF0 PYRIDOXINE-5-PHOSPHATE OXIDASE PYRIDOXINE-5'-PHOSPHATE OXIDASE oxidase#PC00175 Pyridoxal-5-phosphate biosynthesis#P02759>Pyridoxine-5-phosphate oxidase#P03061;Pyridoxal phosphate salvage pathway#P02770>Pyridoxine-5-phosphate oxidase#P03123;Vitamin B6 metabolism#P02787>Pyridoxamine phosphate oxidase#P03236;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine-5-phosphate oxidase#P03120 HUMAN|HGNC=14646|UniProtKB=Q9BY78 Q9BY78 RNF26 PTHR22696:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF26 E3 UBIQUITIN-PROTEIN LIGASE RNF26 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=13368|UniProtKB=Q96PG2 Q96PG2 MS4A10 PTHR23320:SF5 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 10 transporter#PC00227 HUMAN|HGNC=16200|UniProtKB=Q9H4Z3 Q9H4Z3 PCIF1 PTHR21727:SF0 PHOSPHORYLATED CTD INTERACTING FACTOR 1 MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE HUMAN|HGNC=21099|UniProtKB=Q5T9G4 Q5T9G4 ARMC12 PTHR47144:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 12 ARMADILLO REPEAT-CONTAINING PROTEIN 12 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=3631|UniProtKB=P14324 P14324 FDPS PTHR11525:SF0 FARNESYL-PYROPHOSPHATE SYNTHETASE FARNESYL PYROPHOSPHATE SYNTHASE prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 acyltransferase#PC00042 Cholesterol biosynthesis#P00014>Geranyl trans-transferase#P00493 HUMAN|HGNC=1957|UniProtKB=P32297 P32297 CHRNA3 PTHR18945:SF831 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA3#P06595;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=1108|UniProtKB=P47974 P47974 ZFP36L2 PTHR12547:SF100 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36L2 RNA metabolism protein#PC00031 HUMAN|HGNC=10056|UniProtKB=Q9Y3C5 Q9Y3C5 RNF11 PTHR46359:SF1 GEO07743P1 RING FINGER PROTEIN 11 HUMAN|HGNC=21193|UniProtKB=Q3MJ62 Q3MJ62 ZSCAN23 PTHR23226:SF76 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 23 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26704|UniProtKB=Q3MJ40 Q3MJ40 CCDC144B PTHR22245:SF3 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 144A-RELATED HUMAN|HGNC=24802|UniProtKB=Q68CQ1 Q68CQ1 MROH7 PTHR23120:SF17 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 7 HUMAN|HGNC=25420|UniProtKB=Q9H0X6 Q9H0X6 RNF208 PTHR22791:SF3 UNCHARACTERIZED RING FINGER PROTEIN 208 HUMAN|HGNC=29528|UniProtKB=Q8WU90 Q8WU90 ZC3H15 PTHR12681:SF0 ZINC FINGER-CONTAINING PROTEIN P48ZNF ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=33739|UniProtKB=Q6ZVX7 Q6ZVX7 NCCRP1 PTHR12125:SF1 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 50 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 HUMAN|HGNC=27849|UniProtKB=Q9BUH6 Q9BUH6 PAXX PTHR28586:SF1 PROTEIN PAXX PROTEIN PAXX molecular adaptor activity#GO:0060090;binding#GO:0005488 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26429|UniProtKB=Q5H9U9 Q5H9U9 DDX60L PTHR44533:SF1 DEAD/H RNA HELICASE, PUTATIVE-RELATED ATP-DEPENDENT RNA HELICASE DDX60-LIKE-RELATED HUMAN|GeneCards=L1RE1|UniProtKB=Q9UN81 Q9UN81 L1RE1 PTHR11505:SF212 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular process#GO:0009987;transposition#GO:0032196 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 HUMAN|HGNC=17943|UniProtKB=Q9GZP9 Q9GZP9 DERL2 PTHR11009:SF5 DER1-LIKE PROTEIN, DERLIN DERLIN-2 enzyme binding#GO:0019899;protein binding#GO:0005515;protease binding#GO:0002020;binding#GO:0005488 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;ubiquitin-dependent ERAD pathway#GO:0030433;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane protein complex#GO:0098796;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=14285|UniProtKB=Q96DS6 Q96DS6 MS4A6E PTHR23320:SF153 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 6E transporter#PC00227 HUMAN|HGNC=24859|UniProtKB=O95619 O95619 YEATS4 PTHR23195:SF15 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 4 general transcription factor#PC00259 HUMAN|HGNC=18039|UniProtKB=Q9UGL1 Q9UGL1 KDM5B PTHR10694:SF3 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5B demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=20289|UniProtKB=Q8N752 Q8N752 CSNK1A1L PTHR11909:SF139 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA-LIKE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;peptidyl-serine modification#GO:0018209;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Hedgehog signaling pathway#P00025>Casein kinase I#P00681;Parkinson disease#P00049>Casein kinase I#P01242 HUMAN|HGNC=10732|UniProtKB=Q92854 Q92854 SEMA4D PTHR11036:SF18 SEMAPHORIN SEMAPHORIN-4D receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;skeletal system development#GO:0001501;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;regulation of cellular component movement#GO:0051270;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;regulation of GTPase activity#GO:0043087;ossification#GO:0001503;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of neuron differentiation#GO:0045665;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;taxis#GO:0042330;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;growth#GO:0040007;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;axon guidance#GO:0007411;organic cyclic compound metabolic process#GO:1901360;axon extension#GO:0048675;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;cell morphogenesis involved in differentiation#GO:0000904;negative regulation of biosynthetic process#GO:0009890;regulation of cell development#GO:0060284;positive regulation of catalytic activity#GO:0043085;negative regulation of phosphorus metabolic process#GO:0010563;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;regulation of nucleic acid-templated transcription#GO:1903506;negative regulation of catalytic activity#GO:0043086;transcription by RNA polymerase II#GO:0006366;negative regulation of molecular function#GO:0044092;negative regulation of gene expression#GO:0010629;neuron projection guidance#GO:0097485;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;negative regulation of cellular component movement#GO:0051271;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;macromolecule metabolic process#GO:0043170;regulation of phosphatase activity#GO:0010921;positive regulation of locomotion#GO:0040017;RNA biosynthetic process#GO:0032774;negative regulation of dephosphorylation#GO:0035305;regulation of neuron differentiation#GO:0045664;positive regulation of hydrolase activity#GO:0051345;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;neuron projection morphogenesis#GO:0048812;aromatic compound biosynthetic process#GO:0019438;neuron development#GO:0048666;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;regulation of cell morphogenesis involved in differentiation#GO:0010769;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;regulation of phosphate metabolic process#GO:0019220;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;neural crest cell development#GO:0014032;negative regulation of phosphatase activity#GO:0010923;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of dephosphorylation#GO:0035303;regulation of cell differentiation#GO:0045595;bone development#GO:0060348;regulation of transcription, DNA-templated#GO:0006355;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;cell part morphogenesis#GO:0032990;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;developmental growth involved in morphogenesis#GO:0060560;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;developmental growth#GO:0048589;positive regulation of GTPase activity#GO:0043547;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cell growth#GO:0016049;regulation of RNA metabolic process#GO:0051252;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;response to external stimulus#GO:0009605;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;negative regulation of phosphate metabolic process#GO:0045936;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477;regulation of cellular macromolecule biosynthetic process#GO:2000112 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 Axon guidance mediated by semaphorins#P00007>Sema4D#P00329 HUMAN|HGNC=18312|UniProtKB=Q8NFP0 Q8NFP0 PXT1 PTHR40381:SF1 PEROXISOMAL TESTIS-SPECIFIC PROTEIN 1 PEROXISOMAL TESTIS-SPECIFIC PROTEIN 1 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12712|UniProtKB=Q9H267 Q9H267 VPS33B PTHR11679:SF1 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33B cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=26391|UniProtKB=Q6ZP80 Q6ZP80 TMEM182 PTHR32012:SF0 TRANSMEMBRANE PROTEIN 182-RELATED TRANSMEMBRANE PROTEIN 182 HUMAN|HGNC=24438|UniProtKB=Q8N2G8 Q8N2G8 GHDC PTHR31901:SF5 GH3 DOMAIN-CONTAINING PROTEIN GH3 DOMAIN-CONTAINING PROTEIN ligase activity#GO:0016874;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9779|UniProtKB=O95716 O95716 RAB3D PTHR47980:SF17 LD44762P RAS-RELATED PROTEIN RAB-3D vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;protein secretion#GO:0009306;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=4134|UniProtKB=O60755 O60755 GALR3 PTHR24230:SF17 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 3 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=28652|UniProtKB=Q5SXM1 Q5SXM1 ZNF678 PTHR24384:SF201 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 273-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=20294|UniProtKB=Q5W0Q7 Q5W0Q7 USPL1 PTHR15294:SF3 RETINOVIN-RELATED SUMO-SPECIFIC ISOPEPTIDASE USPL1 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein-specific protease activity#GO:0019783;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;nucleus organization#GO:0006997;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=20800|UniProtKB=Q9NTN3 Q9NTN3 SLC35D1 PTHR11132:SF247 SOLUTE CARRIER FAMILY 35 UDP-GLUCURONIC ACID/UDP-N-ACETYLGALACTOSAMINE TRANSPORTER secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=37249|UniProtKB=Q6PDB4 Q6PDB4 ZNF880 PTHR24377:SF143 IP01015P-RELATED ZINC FINGER PROTEIN 880 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19309|UniProtKB=Q14678 Q14678 KANK1 PTHR24168:SF19 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=3060|UniProtKB=Q86Y01 Q86Y01 DTX1 PTHR12622:SF7 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX1 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=16034|UniProtKB=Q86UB2 Q86UB2 BIVM PTHR16171:SF9 DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED BASIC IMMUNOGLOBULIN-LIKE VARIABLE MOTIF-CONTAINING PROTEIN-RELATED DNA metabolism protein#PC00009 HUMAN|HGNC=28375|UniProtKB=Q8WWF8 Q8WWF8 CAPSL PTHR34524:SF5 CALCYPHOSIN CALCYPHOSIN-LIKE PROTEIN calmodulin-related#PC00061 HUMAN|HGNC=25207|UniProtKB=Q8WV92 Q8WV92 MITD1 PTHR21222:SF1 UNCHARACTERIZED MIT DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=23717|UniProtKB=Q96CX3 Q96CX3 ZNF501 PTHR24404:SF79 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 501 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29625|UniProtKB=A1L453 A1L453 PRSS38 PTHR24250:SF30 CHYMOTRYPSIN-RELATED SERINE PROTEASE 38 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203 HUMAN|HGNC=24886|UniProtKB=Q9Y2L6 Q9Y2L6 FRMD4B PTHR46079:SF1 FERM DOMAIN-CONTAINING PROTEIN 4 FERM DOMAIN-CONTAINING PROTEIN 4B cell junction#GO:0030054;bicellular tight junction#GO:0005923;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;apical junction complex#GO:0043296 HUMAN|HGNC=8918|UniProtKB=P78562 P78562 PHEX PTHR11733:SF133 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX metalloprotease#PC00153 HUMAN|HGNC=11631|UniProtKB=Q9UGU0 Q9UGU0 TCF20 PTHR14955:SF7 RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 20 TRANSCRIPTION FACTOR 20 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=10018|UniProtKB=Q06587 Q06587 RING1 PTHR46076:SF2 E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RING1 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;chromatin binding#GO:0003682;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone ubiquitination#GO:0016574;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;histone H2A ubiquitination#GO:0033522;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=21578|UniProtKB=Q7Z419 Q7Z419 RNF144B PTHR11685:SF104 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF144B ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 envelope#GO:0031975;mitochondrial membrane#GO:0031966;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=20331|UniProtKB=Q14644 Q14644 RASA3 PTHR10194:SF53 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 3 GTPase-activating protein#PC00257 HUMAN|HGNC=16243|UniProtKB=Q9H1R3 Q9H1R3 MYLK2 PTHR24347:SF373 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE 2, SKELETAL/CARDIAC MUSCLE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877;Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514 HUMAN|HGNC=17853|UniProtKB=Q9P2D0 Q9P2D0 IBTK PTHR22872:SF5 BTK-BINDING PROTEIN-RELATED INHIBITOR OF BRUTON TYROSINE KINASE HUMAN|HGNC=17168|UniProtKB=Q9H2M9 Q9H2M9 RAB3GAP2 PTHR12472:SF0 RAB3-GAP REGULATORY DOMAIN RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 G-protein modulator#PC00022 HUMAN|HGNC=19569|UniProtKB=Q8NG84 Q8NG84 OR2AK2 PTHR26453:SF299 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AK2 transmembrane signal receptor#PC00197 HUMAN|HGNC=6350|UniProtKB=O75840 O75840 KLF7 PTHR23235:SF77 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26146|UniProtKB=Q9NQC8 Q9NQC8 IFT46 PTHR13376:SF0 UNCHARACTERIZED INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;intracellular#GO:0005622;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=29846|UniProtKB=O14512 O14512 SOCS7 PTHR10155:SF5 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 7 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phosphorylation#GO:0016310;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 HUMAN|HGNC=10871|UniProtKB=Q92187 Q92187 ST8SIA4 PTHR11987:SF48 ALPHA-2,8-SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-POLY-ALPHA-2,8-SIALYLTRANSFERASE transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=26341|UniProtKB=Q96LM6 Q96LM6 TEX37 PTHR36882:SF1 TESTIS-EXPRESSED SEQUENCE 37 PROTEIN TESTIS-EXPRESSED SEQUENCE 37 PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=17592|UniProtKB=Q9BT67 Q9BT67 NDFIP1 PTHR13396:SF3 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY-INTERACTING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;cation transport#GO:0006812;positive regulation of protein modification process#GO:0031401;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;metal ion transport#GO:0030001;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=987|UniProtKB=P21953 P21953 BCKDHB PTHR42980:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to nutrient#GO:0007584;response to external stimulus#GO:0009605;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 dehydrogenase#PC00092 HUMAN|HGNC=21957|UniProtKB=Q96MP8 Q96MP8 KCTD7 PTHR14499:SF122 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD7 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25640|UniProtKB=Q9NUQ7 Q9NUQ7 UFSP2 PTHR48153:SF2 UFM1-SPECIFIC PROTEASE 2 UFM1-SPECIFIC PROTEASE 2 HUMAN|HGNC=23332|UniProtKB=Q9UBI1 Q9UBI1 COMMD3 PTHR31159:SF1 COMM DOMAIN-CONTAINING PROTEIN 3 COMM DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=30040|UniProtKB=Q9BZM2 Q9BZM2 PLA2G2F PTHR11716:SF8 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP IIF SECRETORY PHOSPHOLIPASE A2 cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipase activity#GO:0004620;anion binding#GO:0043168;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;phospholipid metabolic process#GO:0006644;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;phosphorus metabolic process#GO:0006793;leukocyte cell-cell adhesion#GO:0007159;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;T cell proliferation#GO:0042098;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;negative regulation of cell population proliferation#GO:0008285;regulation of cell adhesion#GO:0030155;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;metabolic process#GO:0008152;negative regulation of T cell proliferation#GO:0042130;lymphocyte activation#GO:0046649;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;cellular metabolic process#GO:0044237;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cell adhesion#GO:0007155;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;primary metabolic process#GO:0044238;regulation of T cell proliferation#GO:0042129;negative regulation of cell adhesion#GO:0007162;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;negative regulation of immune system process#GO:0002683;organophosphate metabolic process#GO:0019637;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;cellular lipid metabolic process#GO:0044255 phospholipase#PC00186 HUMAN|HGNC=23433|UniProtKB=Q8IXQ3 Q8IXQ3 C9orf40 PTHR16003:SF3 C9ORF40 ISOFORM 1 WRNPLPNID DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=9559|UniProtKB=Q13200 Q13200 PSMD2 PTHR10943:SF11 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;proteasome regulatory particle, base subcomplex#GO:0008540;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 HUMAN|HGNC=5393|UniProtKB=Q5VY09 Q5VY09 IER5 PTHR15895:SF12 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 5 PROTEIN HUMAN|HGNC=26294|UniProtKB=C9J442 C9J442 C22orf46 PTHR22379:SF1 RIKEN CDNA 4930407I10 GENE RIKEN CDNA 4930407I10 GENE HUMAN|HGNC=20862|UniProtKB=Q9C0K1 Q9C0K1 SLC39A8 PTHR12191:SF2 SOLUTE CARRIER FAMILY 39 METAL CATION SYMPORTER ZIP8 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=20817|UniProtKB=Q86V71 Q86V71 ZNF429 PTHR24377:SF938 IP01015P-RELATED ZINC FINGER PROTEIN 429-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16722|UniProtKB=Q6NT52 Q6NT52 CGB2 PTHR11515:SF27 GLYCOPROTEIN HORMONE BETA CHAIN CHORIOGONADOTROPIN SUBUNIT BETA 3-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular#GO:0005622 peptide hormone#PC00179 HUMAN|Ensembl=ENSG00000283963|UniProtKB=A0A1W2PPM0 A0A1W2PPM0 ENSG00000283963 PTHR10066:SF67 BETA-GLUCURONIDASE BETA-GLUCURONIDASE-RELATED oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carbohydrate metabolic process#GO:0005975;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 HUMAN|HGNC=30430|UniProtKB=Q9UGK3 Q9UGK3 STAP2 PTHR16186:SF11 SIGNAL-TRANSDUCING ADAPTOR PROTEIN-RELATED SIGNAL-TRANSDUCING ADAPTOR PROTEIN 2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=8185|UniProtKB=P47884 P47884 OR1D4 PTHR48001:SF70 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1D4-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=25443|UniProtKB=Q9NSK7 Q9NSK7 C19orf12 PTHR31493:SF1 NAZO FAMILY MEMBER PROTEIN C19ORF12 HUMAN|HGNC=19946|UniProtKB=Q5T5Y3 Q5T5Y3 CAMSAP1 PTHR21595:SF3 UNCHARACTERIZED CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;negative regulation of biological process#GO:0048519;protein-containing complex disassembly#GO:0032984;cellular protein complex disassembly#GO:0043624;regulation of organelle organization#GO:0033043;microtubule depolymerization#GO:0007019;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 HUMAN|HGNC=8148|UniProtKB=O60890 O60890 OPHN1 PTHR12552:SF2 OLIGOPHRENIN 1 OLIGOPHRENIN-1 GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=32070|UniProtKB=Q96S90 Q96S90 LYSMD1 PTHR20932:SF2 LOC443603 PROTEIN-RELATED AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 1-RELATED HUMAN|HGNC=6439|UniProtKB=P35908 P35908 KRT2 PTHR45616:SF14 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 2 EPIDERMAL HUMAN|HGNC=28310|UniProtKB=Q6JBY9 Q6JBY9 RCSD1 PTHR21669:SF2 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS CAPZ-INTERACTING PROTEIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=6445|UniProtKB=P08729 P08729 KRT7 PTHR45616:SF21 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 7 HUMAN|HGNC=13749|UniProtKB=P98173 P98173 FAM3A PTHR14592:SF11 UNCHARACTERIZED FAM3 PROTEIN FAM3A extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=23614|UniProtKB=Q9NSC7 Q9NSC7 ST6GALNAC1 PTHR45941:SF1 FAMILY NOT NAMED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 1 HUMAN|HGNC=26178|UniProtKB=Q2V2M9 Q2V2M9 FHOD3 PTHR45920:SF3 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FH1/FH2 DOMAIN-CONTAINING PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;animal organ development#GO:0048513;developmental process#GO:0032502;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;cardiac muscle cell development#GO:0055013;cellular component morphogenesis#GO:0032989;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cardiocyte differentiation#GO:0035051;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cortical actin cytoskeleton organization#GO:0030866 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229 HUMAN|HGNC=17553|UniProtKB=Q96SE0 Q96SE0 ABHD1 PTHR10794:SF60 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;acylglycerol lipase activity#GO:0047372;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;fatty acid biosynthetic process#GO:0006633;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 serine protease#PC00203 HUMAN|HGNC=9225|UniProtKB=O75387 O75387 SLC43A1 PTHR20766:SF0 FAMILY NOT NAMED LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 HUMAN|HGNC=9667|UniProtKB=Q14761 Q14761 PTPRCAP PTHR15312:SF1 PROTEIN TYROSINE PHOSPHATASE RECEPTOR TYPE C-ASSOCIATED PROTEIN PROTEIN TYROSINE PHOSPHATASE RECEPTOR TYPE C-ASSOCIATED PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=12530|UniProtKB=P22309 P22309 UGT1A1 PTHR48050:SF8 STEROL 3-BETA-GLUCOSYLTRANSFERASE UDP-GLUCURONOSYLTRANSFERASE 1A1 glycosyltransferase#PC00111 Nicotine degradation#P05914>UGT1A4#P05982 HUMAN|HGNC=17975|UniProtKB=Q9BRK0 Q9BRK0 REEP2 PTHR12300:SF29 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;cytoplasmic microtubule#GO:0005881;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;microtubule#GO:0005874;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 HUMAN|HGNC=18698|UniProtKB=Q9UHL0 Q9UHL0 DDX25 PTHR47958:SF33 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX25 catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;ribonucleoprotein complex localization#GO:0071166;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=4904|UniProtKB=C9JL84 C9JL84 HHLA1 PTHR15299:SF3 HERV-H LTR-ASSOCIATING PROTEIN 1 HERV-H LTR-ASSOCIATING PROTEIN 1 HUMAN|HGNC=9298|UniProtKB=Q96SB3 Q96SB3 PPP1R9B PTHR16154:SF24 NEURABIN NEURABIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 signal transduction#GO:0007165;neurogenesis#GO:0022008;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;cell projection organization#GO:0030030;developmental process#GO:0032502;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;neuron differentiation#GO:0030182;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 synapse#GO:0045202;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=32311|UniProtKB=Q96T53 Q96T53 MBOAT4 PTHR13906:SF3 PORCUPINE GHRELIN O-ACYLTRANSFERASE transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;lipid modification#GO:0030258;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acetyltransferase#PC00038 HUMAN|HGNC=307|UniProtKB=Q08117 Q08117 TLE5 PTHR10814:SF4 TRANSDUCIN-LIKE ENHANCER PROTEIN TLE FAMILY MEMBER 5-RELATED repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein binding#GO:0005515;molecular function regulator#GO:0098772;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 HUMAN|HGNC=28845|UniProtKB=Q71SY5 Q71SY5 MED25 PTHR12433:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=23445|UniProtKB=A6NNL0 A6NNL0 NUTM2B PTHR22879:SF14 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 2A-RELATED HUMAN|HGNC=25541|UniProtKB=P57088 P57088 TMEM33 PTHR12703:SF4 TRANSMEMBRANE PROTEIN 33 TRANSMEMBRANE PROTEIN 33 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;membrane organization#GO:0061024;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=27320|UniProtKB=Q504U0 Q504U0 C4orf46 PTHR31641:SF2 RENAL CANCER DIFFERENTIATION GENE 1 PROTEIN RENAL CANCER DIFFERENTIATION GENE 1 PROTEIN HUMAN|HGNC=4986|UniProtKB=P05204 P05204 HMGN2 PTHR23087:SF13 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-17 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=9566|UniProtKB=P48556 P48556 PSMD8 PTHR12387:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190 HUMAN|HGNC=23448|UniProtKB=B1AL46 B1AL46 NUTM2E PTHR22879:SF14 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 2A-RELATED HUMAN|HGNC=14219|UniProtKB=Q96PK6 Q96PK6 RBM14 PTHR23147:SF53 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 14 nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;binding#GO:0005488;transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;nuclear receptor transcription coactivator activity#GO:0030374 response to external biotic stimulus#GO:0043207;positive regulation of gene expression#GO:0010628;activation of immune response#GO:0002253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;RNA splicing#GO:0008380;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;aromatic compound biosynthetic process#GO:0019438;positive regulation of defense response#GO:0031349;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of response to stimulus#GO:0048584;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of response to external stimulus#GO:0032101;immune response#GO:0006955;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of response to biotic stimulus#GO:0002831;regulation of primary metabolic process#GO:0080090;regulation of innate immune response#GO:0045088;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;activation of innate immune response#GO:0002218;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of nucleic acid-templated transcription#GO:1903506;RNA splicing, via transesterification reactions#GO:0000375;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of mRNA splicing, via spliceosome#GO:0048024;positive regulation of response to biotic stimulus#GO:0002833;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA splicing factor#PC00148 HUMAN|HGNC=15763|UniProtKB=Q9H1D9 Q9H1D9 POLR3F PTHR12780:SF1 RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;intracellular#GO:0005622;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;transferase complex#GO:1990234;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=27752|UniProtKB=Q86T96 Q86T96 RNF180 PTHR46717:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF180 E3 UBIQUITIN-PROTEIN LIGASE RNF180 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;catecholamine metabolic process#GO:0006584;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;regulation of proteolysis#GO:0030162;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=26114|UniProtKB=Q96F86 Q96F86 EDC3 PTHR13612:SF0 UNCHARACTERIZED ENHANCER OF MRNA-DECAPPING PROTEIN 3 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cytoplasmic mRNA processing body assembly#GO:0033962;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=28405|UniProtKB=Q86Y97 Q86Y97 KMT5C PTHR12977:SF11 SUPPRESSOR OF VARIEGATION 4-20-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE KMT5C N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone methylation#GO:0016571;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;histone lysine methylation#GO:0034968;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;peptidyl-lysine trimethylation#GO:0018023;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18581|UniProtKB=Q8N485 Q8N485 LIX1 PTHR31139:SF5 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG PROTEIN LIMB EXPRESSION 1 HOMOLOG process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagosome maturation#GO:0097352;cellular process#GO:0009987;autophagy#GO:0006914;cellular catabolic process#GO:0044248;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=20063|UniProtKB=Q86T82 Q86T82 USP37 PTHR24006:SF686 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 37 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;mitotic nuclear division#GO:0140014;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;organelle fission#GO:0048285;cell cycle#GO:0007049 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=11210|UniProtKB=Q15506 Q15506 SPA17 PTHR10699:SF16 NEUROMODULIN SPERM SURFACE PROTEIN SP17 protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;C2 axonemal microtubule#GO:1990720;B axonemal microtubule#GO:0097650;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;sperm principal piece#GO:0097228;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;axonemal microtubule#GO:0005879 HUMAN|HGNC=29530|UniProtKB=Q96AC6 Q96AC6 KIFC2 PTHR24115:SF479 KINESIN-RELATED KINESIN-LIKE PROTEIN KIFC2 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;mitotic spindle assembly#GO:0090307;movement of cell or subcellular component#GO:0006928;spindle assembly#GO:0051225;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=29366|UniProtKB=Q9C0D2 Q9C0D2 CEP295 PTHR21553:SF25 ALMS1-RELATED CENTROSOMAL PROTEIN OF 295 KDA cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;regulation of centrosome duplication#GO:0010824 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=29077|UniProtKB=Q96RY7 Q96RY7 IFT140 PTHR15722:SF7 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;intraciliary retrograde transport#GO:0035721;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 structural protein#PC00211 HUMAN|HGNC=26199|UniProtKB=Q9H079 Q9H079 KATNBL1 PTHR14682:SF1 KATNB1-LIKE PROTEIN 1 KATNB1-LIKE PROTEIN 1 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=20101|UniProtKB=Q8N9W8 Q8N9W8 FAM71D PTHR22574:SF6 UNCHARACTERIZED PROTEIN FAM71D membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=9483|UniProtKB=P07478 P07478 PRSS2 PTHR24264:SF57 TRYPSIN-RELATED TRYPSIN-2 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=17798|UniProtKB=P49750 P49750 YLPM1 PTHR13413:SF0 YLP MOTIF CONTAINING PROTEIN NUCLEAR PROTEIN ZAP YLP MOTIF-CONTAINING PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;telomere organization#GO:0032200;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;chromosome organization#GO:0051276;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=31886|UniProtKB=P0C672 P0C672 TSPAN19 PTHR19282:SF211 TETRASPANIN TETRASPANIN-19 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=6142|UniProtKB=P23229 P23229 ITGA6 PTHR23220:SF9 INTEGRIN ALPHA INTEGRIN ALPHA-6 integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=14895|UniProtKB=Q9BZM4 Q9BZM4 ULBP3 PTHR16675:SF199 MHC CLASS I-RELATED UL16-BINDING PROTEIN 3 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=31685|UniProtKB=Q9NQA3 Q9NQA3 WASH6P PTHR23331:SF3 CXYORF1 WAS PROTEIN FAMILY HOMOLOG 4-RELATED HUMAN|HGNC=29789|UniProtKB=Q9ULD2 Q9ULD2 MTUS1 PTHR24200:SF7 TOUCAN, ISOFORM A MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7618|UniProtKB=O14974 O14974 PPP1R12A PTHR24179:SF20 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12A phosphatase binding#GO:0019902;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphatase regulator activity#GO:0019208;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578 supramolecular complex#GO:0099080;Z disc#GO:0030018;A band#GO:0031672;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;sarcomere#GO:0030017;myofibril#GO:0030016;I band#GO:0031674 phosphatase modulator#PC00184 HUMAN|HGNC=29796|UniProtKB=Q9Y2Q5 Q9Y2Q5 LAMTOR2 PTHR13323:SF4 LATE ENDOSOMAL/LYSOSOMAL MP1 INTERACTING PROTEIN RAGULATOR COMPLEX PROTEIN LAMTOR2 signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;TOR signaling#GO:0031929;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 HUMAN|HGNC=1241|UniProtKB=P02745 P02745 C1QA PTHR15427:SF26 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT A HUMAN|HGNC=33776|UniProtKB=Q6ZQR2 Q6ZQR2 CFAP77 PTHR28617:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77 structural protein#PC00211 HUMAN|HGNC=30755|UniProtKB=Q7Z2V1 Q7Z2V1 C16orf82 PTHR40139:SF1 PROTEIN TNT PROTEIN TNT HUMAN|HGNC=9871|UniProtKB=P20936 P20936 RASA1 PTHR10194:SF60 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 1 GTPase-activating protein#PC00257 Angiogenesis#P00005>RasGAP#P00190;Interleukin signaling pathway#P00036>RasGAP#P00975;EGF receptor signaling pathway#P00018>GAP#P00546;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Ras#P00886;Angiogenesis#P00005>GAP#P00205;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646 HUMAN|HGNC=8667|UniProtKB=Q9Y5I0 Q9Y5I0 PCDHA13 PTHR24028:SF101 CADHERIN-87A PROTOCADHERIN ALPHA-13 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=51245|UniProtKB=A0A087X1G2 A0A087X1G2 TBC1D3K PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=11529|UniProtKB=P16422 P16422 EPCAM PTHR14168:SF2 TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER EPITHELIAL CELL ADHESION MOLECULE HUMAN|HGNC=7619|UniProtKB=O60237 O60237 PPP1R12B PTHR24179:SF18 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12B phosphatase binding#GO:0019902;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphatase regulator activity#GO:0019208;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578 supramolecular complex#GO:0099080;Z disc#GO:0030018;A band#GO:0031672;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;sarcomere#GO:0030017;myofibril#GO:0030016;I band#GO:0031674 phosphatase modulator#PC00184 HUMAN|HGNC=239|UniProtKB=P40145 P40145 ADCY8 PTHR45627:SF1 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 8 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 HUMAN|HGNC=4199|UniProtKB=Q92616 Q92616 GCN1 PTHR23346:SF7 TRANSLATIONAL ACTIVATOR GCN1-RELATED EIF-2-ALPHA KINASE ACTIVATOR GCN1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=23531|UniProtKB=Q5VZY2 Q5VZY2 PLPP4 PTHR10165:SF90 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphatase#PC00181 HUMAN|HGNC=11026|UniProtKB=P08195 P08195 SLC3A2 PTHR46673:SF1 4F2 CELL-SURFACE ANTIGEN HEAVY CHAIN 4F2 CELL-SURFACE ANTIGEN HEAVY CHAIN HUMAN|HGNC=188|UniProtKB=O14672 O14672 ADAM10 PTHR45702:SF4 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 10 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 synapse#GO:0045202;cell junction#GO:0030054;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 protease#PC00190 Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 HUMAN|HGNC=17589|UniProtKB=Q8WV07 Q8WV07 LTO1 PTHR12900:SF6 MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 PROTEIN LTO1 HOMOLOG DNA repair#GO:0006281;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;reproductive process#GO:0022414;organic substance metabolic process#GO:0071704;nucleotide-excision repair#GO:0006289;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;mitotic DNA integrity checkpoint#GO:0044774;cell cycle phase transition#GO:0044770;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;response to stress#GO:0006950;reproduction#GO:0000003;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;cellular response to stress#GO:0033554;cell cycle G2/M phase transition#GO:0044839;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;double-strand break repair#GO:0006302;mitotic cell cycle phase transition#GO:0044772;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;intra-S DNA damage checkpoint#GO:0031573;mitotic cell cycle process#GO:1903047;telomere maintenance#GO:0000723;mitotic DNA replication checkpoint#GO:0033314;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;mitotic DNA damage checkpoint#GO:0044773;homeostatic process#GO:0042592;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA replication checkpoint#GO:0000076;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 HUMAN|HGNC=22965|UniProtKB=Q7Z412 Q7Z412 PEX26 PTHR16262:SF2 PEROXISOME ASSEMBLY PROTEIN 26 PEROXISOME ASSEMBLY PROTEIN 26 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein targeting to peroxisome#GO:0006625;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein localization to peroxisome#GO:0072662;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=14132|UniProtKB=Q9BZ29 Q9BZ29 DOCK9 PTHR23317:SF77 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 9 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=3363|UniProtKB=P49961 P49961 ENTPD1 PTHR11782:SF32 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1 nucleotide phosphatase#PC00173 HUMAN|HGNC=9338|UniProtKB=P02812 P02812 PRB2 PTHR23203:SF16 PROLINE-RICH PROTEIN BASIC SALIVARY PROLINE-RICH PROTEIN 1-RELATED antimicrobial response protein#PC00051 HUMAN|HGNC=833|UniProtKB=P36542 P36542 ATP5F1C PTHR11693:SF31 ATP SYNTHASE GAMMA CHAIN ATP SYNTHASE SUBUNIT GAMMA, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide biosynthetic process#GO:0009152 membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;proton-transporting ATP synthase complex#GO:0045259;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular#GO:0005622 ATP synthase#PC00002 ATP synthesis#P02721>F1 gamma#P02796 HUMAN|HGNC=26265|UniProtKB=Q5SY16 Q5SY16 NOL9 PTHR12755:SF3 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=16051|UniProtKB=Q8TEW0 Q8TEW0 PARD3 PTHR16484:SF10 PARTITIONING DEFECTIVE 3 RELATED PARTITIONING DEFECTIVE 3 HOMOLOG lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;biological adhesion#GO:0022610;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of cell polarity#GO:0030010;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;centrosome localization#GO:0051642;establishment of localization in cell#GO:0051649;establishment or maintenance of apical/basal cell polarity#GO:0035088;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;establishment or maintenance of bipolar cell polarity#GO:0061245 cytoplasm#GO:0005737;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;cell junction#GO:0030054;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical junction complex#GO:0043296;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 HUMAN|HGNC=558|UniProtKB=Q9Y6Q5 Q9Y6Q5 AP1M2 PTHR10529:SF234 AP COMPLEX SUBUNIT MU AP-1 COMPLEX SUBUNIT MU-2 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 HUMAN|HGNC=2594|UniProtKB=P11511 P11511 CYP19A1 PTHR24291:SF43 CYTOCHROME P450 FAMILY 4 AROMATASE oxygenase#PC00177 Androgen/estrogene/progesterone biosynthesis#P02727>Aromatase#P02828 HUMAN|HGNC=4564|UniProtKB=Q13322 Q13322 GRB10 PTHR11243:SF4 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 10 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of signal transduction#GO:0009966;cellular response to insulin stimulus#GO:0032869;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;Wnt signaling pathway#GO:0016055;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178 scaffold/adaptor protein#PC00226 HUMAN|HGNC=10254|UniProtKB=Q03395 Q03395 ROM1 PTHR19282:SF234 TETRASPANIN ROD OUTER SEGMENT MEMBRANE PROTEIN 1 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=11010|UniProtKB=P22732 P22732 SLC2A5 PTHR23503:SF32 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 5 HUMAN|HGNC=20758|UniProtKB=Q96K21 Q96K21 ZFYVE19 PTHR46603:SF1 ABSCISSION/NOCUT CHECKPOINT REGULATOR ABSCISSION/NOCUT CHECKPOINT REGULATOR HUMAN|HGNC=18439|UniProtKB=Q8NFR9 Q8NFR9 IL17RE PTHR15583:SF5 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR E signaling receptor activity#GO:0038023;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;cytokine binding#GO:0019955 transmembrane signal receptor#PC00197 HUMAN|HGNC=16851|UniProtKB=Q5JS13 Q5JS13 RALGPS1 PTHR23113:SF167 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=10822|UniProtKB=P55822 P55822 SH3BGR PTHR12232:SF1 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|Gene=YI024_HUMAN|UniProtKB=Q5PR19 Q5PR19 - PTHR11639:SF135 S100 CALCIUM-BINDING PROTEIN UPF0607 PROTEIN ENSP00000381514-RELATED protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=402|UniProtKB=P00352 P00352 ALDH1A1 PTHR11699:SF140 ALDEHYDE DEHYDROGENASE-RELATED RETINAL DEHYDROGENASE 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=6933|UniProtKB=P33032 P33032 MC5R PTHR22750:SF5 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 5 signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=25552|UniProtKB=Q5VTB9 Q5VTB9 RNF220 PTHR13459:SF1 UNCHARACTERIZED E3 UBIQUITIN-PROTEIN LIGASE RNF220 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=15934|UniProtKB=Q8IXH7 Q8IXH7 NELFCD PTHR12144:SF0 NEGATIVE ELONGATION FACTOR D NEGATIVE ELONGATION FACTOR C/D RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of DNA-templated transcription, elongation#GO:0032784;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;regulation of transcription elongation from RNA polymerase II promoter#GO:0034243;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;transcription elongation from RNA polymerase II promoter#GO:0006368;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023 HUMAN|HGNC=6186|UniProtKB=P26440 P26440 IVD PTHR43884:SF12 ACYL-COA DEHYDROGENASE ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092 HUMAN|HGNC=851|UniProtKB=P38606 P38606 ATP6V1A PTHR43607:SF1 V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;whole membrane#GO:0098805 ATP synthase#PC00002 HUMAN|HGNC=30146|UniProtKB=A6NJG6 A6NJG6 ARGFX PTHR45793:SF16 HOMEOBOX PROTEIN ARGININE-FIFTY HOMEOBOX cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=13821|UniProtKB=Q9GZZ7 Q9GZZ7 GFRA4 PTHR10269:SF2 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=13176|UniProtKB=Q13422 Q13422 IKZF1 PTHR24404:SF36 ZINC FINGER PROTEIN DNA-BINDING PROTEIN IKAROS cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11732|UniProtKB=Q96S53 Q96S53 TESK2 PTHR46485:SF6 LIM DOMAIN KINASE 1 DUAL SPECIFICITY TESTIS-SPECIFIC PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16352|UniProtKB=Q9UI43 Q9UI43 MRM2 PTHR10920:SF18 RIBOSOMAL RNA METHYLTRANSFERASE RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA methyltransferase#PC00033 HUMAN|HGNC=11960|UniProtKB=Q6Y7W6 Q6Y7W6 GIGYF2 PTHR14445:SF38 GRB10 INTERACTING GYF PROTEIN GRB10-INTERACTING GYF PROTEIN 2 HUMAN|HGNC=17316|UniProtKB=O43615 O43615 TIMM44 PTHR10721:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 protein binding#GO:0005515;chaperone binding#GO:0051087;binding#GO:0005488 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 transporter#PC00227 HUMAN|HGNC=5171|UniProtKB=P02790 P02790 HPX PTHR10201:SF136 MATRIX METALLOPROTEINASE HEMOPEXIN hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;porphyrin-containing compound metabolic process#GO:0006778;cellular component organization#GO:0016043;pigment metabolic process#GO:0042440;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;organic cyclic compound metabolic process#GO:1901360;extracellular structure organization#GO:0043062;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152 metalloprotease#PC00153 HUMAN|HGNC=15466|UniProtKB=Q9HC57 Q9HC57 WFDC1 PTHR14308:SF0 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;growth#GO:0040007;cellular component organization#GO:0016043;regulation of growth#GO:0040008;regulation of cellular component organization#GO:0051128;cell growth#GO:0016049;cellular process#GO:0009987;regulation of cell growth#GO:0001558 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=24349|UniProtKB=Q7Z3E2 Q7Z3E2 CCDC186 PTHR18911:SF5 CTCL TUMOR ANTIGEN HD-CL-01 COILED-COIL DOMAIN-CONTAINING PROTEIN 186 HUMAN|HGNC=6514|UniProtKB=O95835 O95835 LATS1 PTHR24356:SF138 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE LATS1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;cell cycle process#GO:0022402;growth#GO:0040007;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of growth#GO:0040008;mitotic cell cycle process#GO:1903047;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;positive regulation of programmed cell death#GO:0043068;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;cell death#GO:0008219;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of apoptotic process#GO:0042981;developmental growth#GO:0048589;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;hippo signaling#GO:0035329;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell cycle#GO:0007049;peptidyl-serine modification#GO:0018209;multicellular organismal process#GO:0032501;organelle fission#GO:0048285;positive regulation of cell death#GO:0010942 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=6138|UniProtKB=P08514 P08514 ITGA2B PTHR23220:SF73 INTEGRIN ALPHA INTEGRIN ALPHA-IIB integrin#PC00126 Blood coagulation#P00011>GP IIb#P00410;Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=17719|UniProtKB=Q9NRR8 Q9NRR8 CDC42SE1 PTHR13502:SF3 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CDC42 SMALL EFFECTOR PROTEIN 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=9581|UniProtKB=Q9H939 Q9H939 PSTPIP2 PTHR23065:SF9 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;protein-containing complex subunit organization#GO:0043933 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=18254|UniProtKB=Q96HZ4 Q96HZ4 HES6 PTHR10985:SF11 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION COFACTOR HES-6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=1177|UniProtKB=Q9UHR6 Q9UHR6 ZNHIT2 PTHR15555:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 2 PROTEIN FON -RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=17389|UniProtKB=Q92484 Q92484 SMPDL3A PTHR10340:SF24 SPHINGOMYELIN PHOSPHODIESTERASE ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3A phosphodiesterase#PC00185 HUMAN|HGNC=31092|UniProtKB=Q24JP5 Q24JP5 TMEM132A PTHR13388:SF9 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 132A HUMAN|HGNC=33593|UniProtKB=Q6L9T8 Q6L9T8 FAM72D PTHR31841:SF1 PROTEIN FAM72A-RELATED PROTEIN FAM72A-RELATED cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=16930|UniProtKB=Q8IWX8 Q8IWX8 CHERP PTHR12323:SF0 SR-RELATED CTD ASSOCIATED FACTOR 6 CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=23098|UniProtKB=Q9NVK5 Q9NVK5 FGFR1OP2 PTHR12186:SF3 SIKE FAMILY MEMBER FGFR1 ONCOGENE PARTNER 2 response to stimulus#GO:0050896;response to stress#GO:0006950;response to wounding#GO:0009611 HUMAN|HGNC=23401|UniProtKB=Q9Y6A9 Q9Y6A9 SPCS1 PTHR13202:SF0 MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 1 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;establishment of protein localization#GO:0045184;protein processing#GO:0016485;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;cellular protein metabolic process#GO:0044267;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to endoplasmic reticulum#GO:0070972;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;signal peptide processing#GO:0006465;cellular amide metabolic process#GO:0043603 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 HUMAN|HGNC=7141|UniProtKB=P12872 P12872 MLN PTHR14156:SF0 MOTILIN PROMOTILIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 HUMAN|HGNC=16016|UniProtKB=Q5KU26 Q5KU26 COLEC12 PTHR24023:SF910 COLLAGEN ALPHA COLLECTIN-12 signaling receptor activity#GO:0038023;low-density lipoprotein particle binding#GO:0030169;molecular transducer activity#GO:0060089;protein-containing complex binding#GO:0044877;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=9542|UniProtKB=P28074 P28074 PSMB5 PTHR11599:SF51 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-5 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 HUMAN|HGNC=25704|UniProtKB=Q9H7M6 Q9H7M6 ZSWIM4 PTHR22619:SF4 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 4 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;regulation of locomotion#GO:0040012;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;regulation of chemotaxis#GO:0050920;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;regulation of response to external stimulus#GO:0032101;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;generation of neurons#GO:0048699 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234 HUMAN|HGNC=28390|UniProtKB=Q8TBF2 Q8TBF2 PRXL2B PTHR28630:SF23 FAMILY NOT NAMED PROSTAMIDE/PROSTAGLANDIN F SYNTHASE oxidation-reduction process#GO:0055114;metabolic process#GO:0008152 HUMAN|HGNC=11614|UniProtKB=Q15560 Q15560 TCEA2 PTHR11477:SF3 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 2 general transcription factor#PC00259 HUMAN|HGNC=19952|UniProtKB=A0PG75 A0PG75 PLSCR5 PTHR23248:SF25 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE FAMILY MEMBER 5 phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;plasma membrane organization#GO:0007009;ion transport#GO:0006811;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=28566|UniProtKB=Q8IYX7 Q8IYX7 SAXO1 PTHR31516:SF9 STABILIZER OF AXONEMAL MICROTUBULES 2 STABILIZER OF AXONEMAL MICROTUBULES 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;microtubule anchoring#GO:0034453;cellular process#GO:0009987 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;C2 axonemal microtubule#GO:1990720;B axonemal microtubule#GO:0097650;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;C1 axonemal microtubule#GO:1990719;microtubule organizing center#GO:0005815;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;centriole#GO:0005814;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;ciliary basal body#GO:0036064;axonemal central apparatus#GO:1990716;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;axonemal microtubule#GO:0005879 HUMAN|HGNC=21292|UniProtKB=Q9UJD0 Q9UJD0 RIMS3 PTHR12157:SF25 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 3 Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;ion channel binding#GO:0044325;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rab GTPase binding#GO:0017137 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=23199|UniProtKB=Q8N456 Q8N456 LRRC18 PTHR45752:SF146 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 18 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6119|UniProtKB=Q15306 Q15306 IRF4 PTHR11949:SF6 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=13527|UniProtKB=Q9Y5K8 Q9Y5K8 ATP6V1D PTHR11671:SF1 V-TYPE ATP SYNTHASE SUBUNIT D V-TYPE PROTON ATPASE SUBUNIT D inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 HUMAN|HGNC=4429|UniProtKB=Q14789 Q14789 GOLGB1 PTHR18887:SF2 GOLGI-ASSOCIATED PROTEIN GCP360-RELATED GOLGIN SUBFAMILY B MEMBER 1 HUMAN|HGNC=318|UniProtKB=P20933 P20933 AGA PTHR10188:SF38 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 HUMAN|HGNC=23155|UniProtKB=A0PJK1 A0PJK1 SLC5A10 PTHR11819:SF128 SOLUTE CARRIER FAMILY 5 SODIUM/GLUCOSE COTRANSPORTER 5 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sugar transmembrane transporter activity#GO:0051119;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=30248|UniProtKB=Q9BZL3 Q9BZL3 SMIM3 PTHR37859:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 3 SMALL INTEGRAL MEMBRANE PROTEIN 3 HUMAN|HGNC=25408|UniProtKB=Q9BQI6 Q9BQI6 SLF1 PTHR46677:SF1 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1 HUMAN|HGNC=28358|UniProtKB=Q8N465 Q8N465 D2HGDH PTHR43716:SF1 D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092 HUMAN|HGNC=16312|UniProtKB=Q8N743 Q8N743 KIR3DL3 PTHR11738:SF177 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL3 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=30555|UniProtKB=Q96D03 Q96D03 DDIT4L PTHR12478:SF17 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 DNA DAMAGE-INDUCIBLE TRANSCRIPT 4-LIKE PROTEIN regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;intracellular signal transduction#GO:0035556;signaling#GO:0023052;TOR signaling#GO:0031929 HUMAN|HGNC=16652|UniProtKB=Q9HD33 Q9HD33 MRPL47 PTHR21183:SF18 RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED 39S RIBOSOMAL PROTEIN L47, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=29320|UniProtKB=Q5W0V3 Q5W0V3 FAM160B1 PTHR21705:SF10 RAI16 PROTEIN-RELATED PROTEIN FAM160B1 HUMAN|HGNC=19|UniProtKB=Q16613 Q16613 AANAT PTHR10908:SF0 SEROTONIN N-ACETYLTRANSFERASE SEROTONIN N-ACETYLTRANSFERASE acetyltransferase#PC00038 HUMAN|HGNC=10329|UniProtKB=P46776 P46776 RPL27A PTHR11721:SF27 60S RIBOSOMAL PROTEIN L27A 60S RIBOSOMAL PROTEIN L27A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=12648|UniProtKB=Q9P0L0 Q9P0L0 VAPA PTHR10809:SF131 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A protein binding#GO:0005515;binding#GO:0005488 cellular developmental process#GO:0048869;cellular localization#GO:0051641;neurogenesis#GO:0022008;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;cell projection organization#GO:0030030;membrane organization#GO:0061024;developmental process#GO:0032502;multicellular organism development#GO:0007275;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=13884|UniProtKB=Q9H172 Q9H172 ABCG4 PTHR48041:SF75 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 4 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=4098|UniProtKB=P0DTW1 P0DTW1 GAGE1 PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=33433|UniProtKB=Q6IMI4 Q6IMI4 SULT6B1 PTHR11783:SF55 SULFOTRANSFERASE SULT SULFOTRANSFERASE 6B1 transferase#PC00220 HUMAN|HGNC=33876|UniProtKB=P0CV98 P0CV98 TSPY3 PTHR11875:SF12 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED PROTEIN 1-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=938|UniProtKB=O95816 O95816 BAG2 PTHR12334:SF6 BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 biological regulation#GO:0065007;regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821 chaperone#PC00072 HUMAN|HGNC=24206|UniProtKB=Q9NUP1 Q9NUP1 BLOC1S4 PTHR16230:SF4 CAPPUCCINO BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 4 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622;BLOC-1 complex#GO:0031083 HUMAN|HGNC=29929|UniProtKB=Q8NFH4 Q8NFH4 NUP37 PTHR22806:SF0 NUCLEOPORIN NUP37 P37 -RELATED NUCLEOPORIN NUP37 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=13727|UniProtKB=Q96S59 Q96S59 RANBP9 PTHR12864:SF56 RAN BINDING PROTEIN 9-RELATED RAN-BINDING PROTEIN 9 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=12304|UniProtKB=Q15642 Q15642 TRIP10 PTHR15735:SF17 FCH AND DOUBLE SH3 DOMAINS PROTEIN CDC42-INTERACTING PROTEIN 4 HUMAN|HGNC=3228|UniProtKB=Q15768 Q15768 EFNB3 PTHR11304:SF34 EPHRIN EPHRIN-B3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=23089|UniProtKB=Q86YT5 Q86YT5 SLC13A5 PTHR10283:SF109 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 5 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;succinate transmembrane transporter activity#GO:0015141;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;dicarboxylic acid transmembrane transporter activity#GO:0005310;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;citrate transport#GO:0015746;anion transmembrane transport#GO:0098656 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=791|UniProtKB=P18850 P18850 ATF6 PTHR46164:SF1 ATF6, ISOFORM C CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-6 ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;response to endoplasmic reticulum stress#GO:0034976;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;response to unfolded protein#GO:0006986;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 Apoptosis signaling pathway#P00006>ATF#P00302 HUMAN|HGNC=1808|UniProtKB=O14627 O14627 CDX4 PTHR24332:SF15 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=15017|UniProtKB=Q6IEZ7 Q6IEZ7 OR2T5 PTHR26453:SF161 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T29-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=1916|UniProtKB=Q86WJ1 Q86WJ1 CHD1L PTHR47157:SF1 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1-LIKE CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1-LIKE pyrophosphatase activity#GO:0016462;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=5276|UniProtKB=O43719 O43719 HTATSF1 PTHR15608:SF0 SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2 HIV TAT-SPECIFIC FACTOR 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=23732|UniProtKB=Q66LE6 Q66LE6 PPP2R2D PTHR11871:SF6 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B DELTA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629 HUMAN|HGNC=3592|UniProtKB=Q9Y285 Q9Y285 FARSA PTHR11538:SF40 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=11456|UniProtKB=O00338 O00338 SULT1C2 PTHR11783:SF73 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1C2 transferase#PC00220 HUMAN|HGNC=16816|UniProtKB=Q8TDI0 Q8TDI0 CHD5 PTHR45623:SF6 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 5 HUMAN|HGNC=4854|UniProtKB=O15379 O15379 HDAC3 PTHR48252:SF4 HISTONE DEACETYLASE 2-RELATED HISTONE DEACETYLASE 3 Wnt signaling pathway#P00057>Histone deacetylase#P01472 HUMAN|HGNC=20659|UniProtKB=O60636 O60636 TSPAN2 PTHR19282:SF155 TETRASPANIN TETRASPANIN-2 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=5359|UniProtKB=Q14197 Q14197 MRPL58 PTHR11075:SF54 PEPTIDE CHAIN RELEASE FACTOR PEPTIDYL-TRNA HYDROLASE ICT1, MITOCHONDRIAL cellular protein complex disassembly#GO:0043624;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;translational termination#GO:0006415;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;mitochondrial translation#GO:0032543;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 translation release factor#PC00225 HUMAN|HGNC=18517|UniProtKB=Q6EMK4 Q6EMK4 VASN PTHR24373:SF261 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN VASORIN growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;negative regulation of cellular response to growth factor stimulus#GO:0090288;regulation of signaling#GO:0023051;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of cellular response to transforming growth factor beta stimulus#GO:1903844;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;negative regulation of transforming growth factor beta receptor signaling pathway#GO:0030512;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;negative regulation of signal transduction#GO:0009968;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=39005|UniProtKB=P63128 P63128 ERVK-9 PTHR40389:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED HUMAN|HGNC=13941|UniProtKB=Q53GD3 Q53GD3 SLC44A4 PTHR12385:SF37 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 4 anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;cation transmembrane transporter activity#GO:0008324;organophosphate ester transmembrane transporter activity#GO:0015605;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;anion transport#GO:0006820;organic cation transport#GO:0015695;choline transport#GO:0015871 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=23364|UniProtKB=Q969X2 Q969X2 ST6GALNAC6 PTHR45906:SF6 FAMILY NOT NAMED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 6 transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;carbohydrate metabolic process#GO:0005975;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=744|UniProtKB=Q9UBL3 Q9UBL3 ASH2L PTHR10598:SF0 SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 N-methyltransferase activity#GO:0008170;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;double-stranded DNA binding#GO:0003690;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;sequence-specific double-stranded DNA binding#GO:1990837;histone-lysine N-methyltransferase activity#GO:0018024;sequence-specific DNA binding#GO:0043565;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;histone modification#GO:0016570;histone methylation#GO:0016571;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;histone lysine methylation#GO:0034968;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;histone H3-K4 methylation#GO:0051568;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=19876|UniProtKB=Q9H2F5 Q9H2F5 EPC1 PTHR14898:SF6 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB HOMOLOG 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=10995|UniProtKB=Q6PCB7 Q6PCB7 SLC27A1 PTHR43107:SF7 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 1 ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 phospholipid biosynthetic process#GO:0008654;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;phosphatidylinositol biosynthetic process#GO:0006661;organic acid transport#GO:0015849;response to cold#GO:0009409;positive regulation of protein modification process#GO:0031401;lipid biosynthetic process#GO:0008610;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;anion transport#GO:0006820;regulation of lipid biosynthetic process#GO:0046890;cellular protein metabolic process#GO:0044267;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;organic anion transport#GO:0015711;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to nitrogen compound#GO:1901698;multicellular organismal homeostasis#GO:0048871;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of lipid metabolic process#GO:0019216;regulation of phosphorylation#GO:0042325;lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to peptide hormone#GO:0043434;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphatidylglycerol biosynthetic process#GO:0006655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance transport#GO:0071702;positive regulation of transferase activity#GO:0051347;regulation of biosynthetic process#GO:0009889;lipid localization#GO:0010876;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;negative regulation of biosynthetic process#GO:0009890;positive regulation of catalytic activity#GO:0043085;glycerolipid biosynthetic process#GO:0045017;cardiolipin biosynthetic process#GO:0032049;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;carboxylic acid transport#GO:0046942;protein phosphorylation#GO:0006468;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;positive regulation of protein metabolic process#GO:0051247;response to hormone#GO:0009725;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;response to temperature stimulus#GO:0009266;positive regulation of kinase activity#GO:0033674;long-chain fatty acid transport#GO:0015909;monocarboxylic acid transport#GO:0015718;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;lipid transport#GO:0006869;regulation of phosphorus metabolic process#GO:0051174;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;response to abiotic stimulus#GO:0009628;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;organonitrogen compound biosynthetic process#GO:1901566;response to organonitrogen compound#GO:0010243;glycerophospholipid metabolic process#GO:0006650;positive regulation of cellular process#GO:0048522;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;phosphatidylglycerol metabolic process#GO:0046471;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;regulation of phosphate metabolic process#GO:0019220;macromolecule localization#GO:0033036;response to insulin#GO:0032868;macromolecule modification#GO:0043412;transport#GO:0006810;phospholipid metabolic process#GO:0006644;response to endogenous stimulus#GO:0009719;glycerolipid metabolic process#GO:0046486;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;cellular modified amino acid metabolic process#GO:0006575;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;positive regulation of cellular protein metabolic process#GO:0032270;cellular lipid metabolic process#GO:0044255;regulation of transferase activity#GO:0051338 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=16983|UniProtKB=Q8TAK6 Q8TAK6 OLIG1 PTHR19290:SF7 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED OLIGODENDROCYTE TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=4656|UniProtKB=Q13888 Q13888 GTF2H2 PTHR12695:SF2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;cellular response to stress#GO:0033554;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675 general transcription factor#PC00259 HUMAN|HGNC=24295|UniProtKB=A0FGR9 A0FGR9 ESYT3 PTHR45761:SF4 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-3 HUMAN|HGNC=928|UniProtKB=O43286 O43286 B4GALT5 PTHR19300:SF45 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 5 glycosyltransferase#PC00111 HUMAN|HGNC=4628|UniProtKB=Q16772 Q16772 GSTA3 PTHR11571:SF257 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE A3 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;sulfur compound metabolic process#GO:0006790;cellular response to chemical stimulus#GO:0070887;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;response to stimulus#GO:0050896;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular#GO:0005622;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982 transferase#PC00220 HUMAN|HGNC=23159|UniProtKB=Q9H553 Q9H553 ALG2 PTHR45918:SF1 ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2 ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2 transferase#PC00220 HUMAN|HGNC=683|UniProtKB=Q9NR81 Q9NR81 ARHGEF3 PTHR46006:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;Rho protein signal transduction#GO:0007266;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of Ras protein signal transduction#GO:0046578 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=3647|UniProtKB=P22830 P22830 FECH PTHR11108:SF1 FERROCHELATASE FERROCHELATASE, MITOCHONDRIAL lyase activity#GO:0016829;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;porphyrin-containing compound metabolic process#GO:0006778;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;heme metabolic process#GO:0042168;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 Heme biosynthesis#P02746>Ferrochelatase#P02972 HUMAN|HGNC=20859|UniProtKB=Q96H72 Q96H72 SLC39A13 PTHR16950:SF16 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER ZIP13 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 primary active transporter#PC00068 HUMAN|HGNC=29365|UniProtKB=Q9C0D4 Q9C0D4 ZNF518B PTHR24392:SF41 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 518B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29546|UniProtKB=Q96HL8 Q96HL8 SH3YL1 PTHR15629:SF2 SH3YL1 PROTEIN SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1 lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;plasma membrane bounded cell projection assembly#GO:0120031 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 HUMAN|HGNC=11295|UniProtKB=Q86TD4 Q86TD4 SRL PTHR11216:SF71 EH DOMAIN SARCALUMENIN endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=25489|UniProtKB=Q9ULM3 Q9ULM3 YEATS2 PTHR23195:SF7 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 2 general transcription factor#PC00259 HUMAN|HGNC=15577|UniProtKB=P58107 P58107 EPPK1 PTHR23169:SF21 ENVOPLAKIN EPIPLAKIN protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;response to stimulus#GO:0050896;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;response to wounding#GO:0009611;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton organization#GO:0007010;wound healing#GO:0042060;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cytoskeleton#GO:0005856 intermediate filament binding protein#PC00130 HUMAN|HGNC=5156|UniProtKB=P00739 P00739 HPR PTHR24255:SF27 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED HAPTOGLOBIN-RELATED PROTEIN serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;inflammatory response#GO:0006954;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;defense response#GO:0006952;protein metabolic process#GO:0019538;positive regulation of cell death#GO:0010942;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=19177|UniProtKB=Q9NX76 Q9NX76 CMTM6 PTHR22776:SF25 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 6 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=23167|UniProtKB=Q86U02 Q86U02 LINC00596 PTHR46254:SF6 PROTEIN GVQW1-RELATED HIGH MOBILITY GROUP AT-HOOK 2 HUMAN|HGNC=11517|UniProtKB=P20366 P20366 TAC1 PTHR11250:SF3 TACHYKININ PROTACHYKININ-1 CCKR signaling map#P06959>TAC1#G07294;CCKR signaling map#P06959>TAC1#G07000 HUMAN|HGNC=37165|UniProtKB=P0CJ75 P0CJ75 MTRNR2L8 PTHR33895:SF15 HUMANIN-LIKE 4 HUMANIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=28781|UniProtKB=Q86V88 Q86V88 MDP1 PTHR17901:SF14 MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1 MAGNESIUM-DEPENDENT PHOSPHATASE 1 phosphatase#PC00181 HUMAN|HGNC=15922|UniProtKB=O75628 O75628 REM1 PTHR45775:SF2 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN REM 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;transporter activity#GO:0005215;channel activity#GO:0015267;calcium channel regulator activity#GO:0005246;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;channel regulator activity#GO:0016247;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=33176|UniProtKB=Q5MJ09 Q5MJ09 SPANXN3 PTHR23425:SF5 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME N3 HUMAN|HGNC=11217|UniProtKB=P38567 P38567 SPAM1 PTHR11769:SF20 HYALURONIDASE HYALURONIDASE PH-20 glycosidase#PC00110 HUMAN|HGNC=14378|UniProtKB=Q9NPE3 Q9NPE3 NOP10 PTHR13305:SF0 RIBOSOME BIOGENESIS PROTEIN NOP10 H/ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 3 RNA metabolism protein#PC00031 HUMAN|HGNC=24931|UniProtKB=Q9NQZ6 Q9NQZ6 ZC4H2 PTHR31058:SF2 ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN neurogenesis#GO:0022008;developmental process#GO:0032502;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;neuron differentiation#GO:0030182;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of neuron differentiation#GO:0045666;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;regulation of neuron differentiation#GO:0045664;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;positive regulation of multicellular organismal process#GO:0051240 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10824|UniProtKB=Q9Y3L3 Q9Y3L3 SH3BP1 PTHR14130:SF12 3BP-1 RELATED RHOGAP BARGIN-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rho GTPase binding#GO:0017048;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;Rac GTPase binding#GO:0048365;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 signal transduction#GO:0007165;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;positive regulation of molecular function#GO:0044093;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of actin cytoskeleton organization#GO:0032956;regulation of hydrolase activity#GO:0051336;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of GTPase activity#GO:0043087;positive regulation of GTPase activity#GO:0043547;positive regulation of catalytic activity#GO:0043085;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036;regulation of Ras protein signal transduction#GO:0046578 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2169|UniProtKB=P26441 P26441 CNTF PTHR15196:SF0 CILIARY NEUROTROPHIC FACTOR CILIARY NEUROTROPHIC FACTOR HUMAN|HGNC=21061|UniProtKB=Q96JX3 Q96JX3 SERAC1 PTHR48182:SF2 PROTEIN SERAC1 PROTEIN SERAC1 HUMAN|HGNC=18667|UniProtKB=Q10713 Q10713 PMPCA PTHR11851:SF192 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA cellular localization#GO:0051641;mitochondrial protein processing#GO:0034982;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;establishment of protein localization#GO:0045184;protein processing#GO:0016485;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein processing involved in protein targeting to mitochondrion#GO:0006627;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 metalloprotease#PC00153 HUMAN|HGNC=18293|UniProtKB=Q5JT25 Q5JT25 RAB41 PTHR24073:SF469 DRAB5-RELATED RAS-RELATED PROTEIN RAB-41 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=29885|UniProtKB=Q659A1 Q659A1 ICE2 PTHR14633:SF3 LITTLE ELONGATION COMPLEX SUBUNIT 2 LITTLE ELONGATION COMPLEX SUBUNIT 2 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 HUMAN|HGNC=12605|UniProtKB=P58418 P58418 CLRN1 PTHR31548:SF4 CLARIN CLARIN-1 multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of sound#GO:0007605;system process#GO:0003008 HUMAN|HGNC=19190|UniProtKB=Q96N67 Q96N67 DOCK7 PTHR23317:SF78 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 7 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=12152|UniProtKB=A0A075B6U6 A0A075B6U6 TRAV8-7 PTHR19367:SF9 T-CELL RECEPTOR ALPHA CHAIN V REGION IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=11407|UniProtKB=Q9BXU1 Q9BXU1 STK31 PTHR12302:SF3 EBNA2 BINDING PROTEIN P100 SERINE/THREONINE-PROTEIN KINASE 31 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=10439|UniProtKB=Q96S38 Q96S38 RPS6KC1 PTHR15508:SF2 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE DELTA-1 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 PDGF signaling pathway#P00047>p90RSK#P01142 HUMAN|HGNC=32459|UniProtKB=P0CG32 P0CG32 ZCCHC18 PTHR23095:SF48 PARANEOPLASTIC ANTIGEN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 18 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=12393|UniProtKB=P53804 P53804 TTC3 PTHR17550:SF6 E3 UBIQUITIN-PROTEIN LIGASE TTC3 E3 UBIQUITIN-PROTEIN LIGASE TTC3 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=20712|UniProtKB=Q9NUE0 Q9NUE0 ZDHHC18 PTHR22883:SF257 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC18 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=19596|UniProtKB=P0C646 P0C646 OR52Z1 PTHR26450:SF63 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52Z1 transmembrane signal receptor#PC00197 HUMAN|HGNC=15632|UniProtKB=Q9NR97 Q9NR97 TLR8 PTHR47410:SF1 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;defense response to virus#GO:0051607;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;response to virus#GO:0009615;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;pattern recognition receptor signaling pathway#GO:0002221;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 HUMAN|HGNC=9966|UniProtKB=Q13127 Q13127 REST PTHR24403:SF64 ZINC FINGER PROTEIN RE1-SILENCING TRANSCRIPTION FACTOR positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1162|UniProtKB=Q70Z53 Q70Z53 FRA10AC1 PTHR11567:SF25 ACID PHOSPHATASE-RELATED PROTEIN FRA10AC1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 phosphatase#PC00181 HUMAN|HGNC=1949|UniProtKB=Q9H2X0 Q9H2X0 CHRD PTHR46526:SF1 CHORDIN CHORDIN DPP-SCW signaling pathway#P06212>SOG#P06266;BMP/activin signaling pathway-drosophila#P06211>SOG#P06252;SCW signaling pathway#P06216>SOG#P06335;DPP signaling pathway#P06213>SOG#P06293 HUMAN|HGNC=22937|UniProtKB=Q86W25 Q86W25 NLRP13 PTHR45690:SF16 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 13 HUMAN|HGNC=24201|UniProtKB=Q9NS64 Q9NS64 RPRM PTHR28649:SF2 PROTEIN REPRIMO-RELATED PROTEIN REPRIMO HUMAN|HGNC=4140|UniProtKB=P17677 P17677 GAP43 PTHR10699:SF15 NEUROMODULIN NEUROMODULIN protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 HUMAN|HGNC=10477|UniProtKB=P19793 P19793 RXRA PTHR24083:SF39 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;response to lipid#GO:0033993;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C4 zinc finger nuclear receptor#PC00169 Vitamin D metabolism and pathway#P04396>RXR#P04602 HUMAN|HGNC=1968|UniProtKB=Q99698 Q99698 LYST PTHR13743:SF86 BEIGE/BEACH-RELATED LYSOSOMAL-TRAFFICKING REGULATOR enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 localization#GO:0051179;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=9593|UniProtKB=P34995 P34995 PTGER1 PTHR11866:SF3 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP1 SUBTYPE signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;organic acid binding#GO:0043177;transmembrane signaling receptor activity#GO:0004888 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of intracellular signal transduction#GO:1902531;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836;PI3 kinase pathway#P00048>GPCR#P01204 HUMAN|HGNC=4433|UniProtKB=P00505 P00505 GOT2 PTHR11879:SF39 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transaminase#PC00216 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 HUMAN|HGNC=6781|UniProtKB=O15525 O15525 MAFG PTHR10129:SF15 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFG cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;epidermis development#GO:0008544;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of epithelial cell differentiation#GO:0030856;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;epidermal cell differentiation#GO:0009913;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;epithelial cell differentiation#GO:0030855;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=10074|UniProtKB=P13489 P13489 RNH1 PTHR24112:SF50 LEUCINE-RICH REPEAT, ISOFORM F-RELATED RIBONUCLEASE INHIBITOR HUMAN|HGNC=14724|UniProtKB=Q8NGQ5 Q8NGQ5 OR9Q1 PTHR48018:SF60 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9Q1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=26841|UniProtKB=Q3SX64 Q3SX64 ODF3L2 PTHR21580:SF48 SHIPPO-1-RELATED OUTER DENSE FIBER PROTEIN 3-LIKE PROTEIN 2 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 structural protein#PC00211 HUMAN|HGNC=6685|UniProtKB=O95237 O95237 LRAT PTHR46678:SF1 LECITHIN RETINOL ACYLTRANSFERASE LECITHIN RETINOL ACYLTRANSFERASE acyltransferase#PC00042 HUMAN|HGNC=9187|UniProtKB=P24928 P24928 POLR2A PTHR19376:SF37 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=12312|UniProtKB=Q15651 Q15651 HMGN3 PTHR23087:SF2 NONHISTONE CHROMOSOMAL PROTEIN HMG HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 3 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=9355|UniProtKB=P30044 P30044 PRDX5 PTHR10430:SF16 PEROXIREDOXIN PEROXIREDOXIN-5, MITOCHONDRIAL oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;regulation of biological quality#GO:0065008;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to oxidative stress#GO:0034599;catabolic process#GO:0009056;cellular response to stress#GO:0033554;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidoreductase#PC00176 HUMAN|HGNC=29599|UniProtKB=Q6TDU7 Q6TDU7 CASC1 PTHR20929:SF11 LUNG ADENOMA SUSCEPTIBILITY 1-RELATED PROTEIN CASC1 HUMAN|HGNC=26510|UniProtKB=Q96MH6 Q96MH6 TMEM68 PTHR22753:SF24 TRANSMEMBRANE PROTEIN 68 TRANSMEMBRANE PROTEIN 68 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=2641|UniProtKB=Q9Y6A2 Q9Y6A2 CYP46A1 PTHR24293:SF0 CYTOCHROME P450 FAMILY 46 SUBFAMILY A CHOLESTEROL 24-HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;heme binding#GO:0020037 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid catabolic process#GO:0006706;cholesterol metabolic process#GO:0008203;alcohol metabolic process#GO:0006066;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;secondary alcohol metabolic process#GO:1902652;organic substance catabolic process#GO:1901575;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxygenase#PC00177 HUMAN|HGNC=29356|UniProtKB=Q9C0F1 Q9C0F1 CEP44 PTHR31477:SF1 CENTROSOMAL PROTEIN OF 44 KDA CENTROSOMAL PROTEIN OF 44 KDA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=6069|UniProtKB=O95050 O95050 INMT PTHR10867:SF33 NNMT/PNMT/TEMT FAMILY MEMBER INDOLETHYLAMINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 methyltransferase#PC00155 Nicotine degradation#P05914>INMT#P05981;Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 HUMAN|HGNC=10516|UniProtKB=P35542 P35542 SAA4 PTHR23424:SF8 SERUM AMYLOID A SERUM AMYLOID A-4 PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 apolipoprotein#PC00052 HUMAN|HGNC=14934|UniProtKB=Q8N6T7 Q8N6T7 SIRT6 PTHR48252:SF6 HISTONE DEACETYLASE 2-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-6 HUMAN|HGNC=24822|UniProtKB=Q9H479 Q9H479 FN3K PTHR12149:SF9 FRUCTOSAMINE 3 KINASE-RELATED PROTEIN FRUCTOSAMINE-3-KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 HUMAN|HGNC=10609|UniProtKB=P22362 P22362 CCL1 PTHR12015:SF5 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 1 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=25565|UniProtKB=Q9NSG2 Q9NSG2 C1orf112 PTHR16071:SF2 CHROMOSOME 1 OPEN READING FRAME 112 CHROMOSOME 5 C1ORF112 HOMOLOG HUMAN|HGNC=20609|UniProtKB=Q13155 Q13155 AIMP2 PTHR13438:SF2 AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2 biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of catalytic activity#GO:0043085;regulation of molecular function#GO:0065009 protein-containing complex#GO:0032991;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26465|UniProtKB=Q7Z739 Q7Z739 YTHDF3 PTHR12357:SF9 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 3 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of translational initiation#GO:0045948;gene expression#GO:0010467;regulation of translational initiation#GO:0006446;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;translational initiation#GO:0006413;positive regulation of RNA metabolic process#GO:0051254;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=6352|UniProtKB=Q9NR64 Q9NR64 KLHL1 PTHR24412:SF75 KELCH PROTEIN KELCH-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17151|UniProtKB=Q9Y5N6 Q9Y5N6 ORC6 PTHR13394:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 ORIGIN RECOGNITION COMPLEX SUBUNIT 6 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;DNA biosynthetic process#GO:0071897;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 replication origin binding protein#PC00199 HUMAN|HGNC=3603|UniProtKB=P35555 P35555 FBN1 PTHR24039:SF22 FIBRILLIN-RELATED FIBRILLIN-1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=18143|UniProtKB=Q86T65 Q86T65 DAAM2 PTHR45725:SF7 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 2 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;positive regulation of signal transduction#GO:0009967;developmental process#GO:0032502;non-canonical Wnt signaling pathway#GO:0035567;regulation of signaling#GO:0023051;gliogenesis#GO:0042063;regulation of multicellular organismal development#GO:2000026;positive regulation of Wnt signaling pathway#GO:0030177;nervous system development#GO:0007399;regulation of cell differentiation#GO:0045595;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;regulation of signal transduction#GO:0009966;central nervous system development#GO:0007417;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;oligodendrocyte differentiation#GO:0048709;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cell development#GO:0048468;positive regulation of canonical Wnt signaling pathway#GO:0090263;response to stimulus#GO:0050896;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of Wnt signaling pathway#GO:0030111;regulation of nervous system development#GO:0051960;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 HUMAN|HGNC=12408|UniProtKB=P0DPH7 P0DPH7 TUBA3C PTHR11588:SF322 TUBULIN TUBULIN ALPHA-3C CHAIN-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 HUMAN|HGNC=17846|UniProtKB=Q9H4F1 Q9H4F1 ST6GALNAC4 PTHR45906:SF4 FAMILY NOT NAMED ALPHA-N-ACETYL-NEURAMINYL-2,3-BETA-GALACTOSYL-1,3-N-ACETYL-GALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;carbohydrate metabolic process#GO:0005975;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=28101|UniProtKB=Q2M2H8 Q2M2H8 MGAM2 PTHR22762:SF122 ALPHA-GLUCOSIDASE MALTASE-GLUCOAMYLASE 2-RELATED glucosidase#PC00108 HUMAN|HGNC=17054|UniProtKB=Q9Y2H2 Q9Y2H2 INPP5F PTHR45662:SF8 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 endosomal transport#GO:0016197;lipid metabolic process#GO:0006629;cellular localization#GO:0051641;transport#GO:0006810;regulation of localization#GO:0032879;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;regulation of vesicle-mediated transport#GO:0060627;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;endocytic recycling#GO:0032456;regulation of transport#GO:0051049;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;phospholipid dephosphorylation#GO:0046839;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=7685|UniProtKB=O43678 O43678 NDUFA2 PTHR12878:SF6 NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 2 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=14452|UniProtKB=Q9NYG5 Q9NYG5 ANAPC11 PTHR11210:SF1 RING BOX ANAPHASE-PROMOTING COMPLEX SUBUNIT 11 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;protein catabolic process#GO:0030163;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;chromosome segregation#GO:0007059;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic sister chromatid segregation#GO:0033047;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;positive regulation of organelle organization#GO:0010638;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;mitotic cell cycle process#GO:1903047;positive regulation of cell cycle process#GO:0090068;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;positive regulation of mitotic nuclear division#GO:0045840;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;metaphase/anaphase transition of cell cycle#GO:0044784;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of mitotic cell cycle#GO:0007346 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=6326|UniProtKB=Q9BVG8 Q9BVG8 KIFC3 PTHR47972:SF5 KINESIN-LIKE PROTEIN KLP-3 KINESIN-LIKE PROTEIN KIFC3 microtubule binding motor protein#PC00156 HUMAN|HGNC=30285|UniProtKB=Q7L099 Q7L099 RUFY3 PTHR45956:SF1 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN PROTEIN RUFY3 regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of cell differentiation#GO:0045595;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cell part morphogenesis#GO:0032990;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;regulation of neuron differentiation#GO:0045664;cellular component morphogenesis#GO:0032989;regulation of neuron projection development#GO:0010975;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of axonogenesis#GO:0050770;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=26886|UniProtKB=Q6ZMZ0 Q6ZMZ0 RNF19B PTHR11685:SF109 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF19B ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=25594|UniProtKB=Q9P2K3 Q9P2K3 RCOR3 PTHR16089:SF13 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 3 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 HUMAN|HGNC=24141|UniProtKB=Q6ZMB0 Q6ZMB0 B3GNT6 PTHR11214:SF24 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE ACETYLGALACTOSAMINYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;cellular polysaccharide biosynthetic process#GO:0033692;cellular polysaccharide metabolic process#GO:0044264;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=2000|UniProtKB=P33552 P33552 CKS2 PTHR23415:SF29 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;cyclin binding#GO:0030332;enzyme regulator activity#GO:0030234;histone binding#GO:0042393;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;ubiquitin binding#GO:0043130;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;regulation of mitotic cell cycle#GO:0007346 SCF ubiquitin ligase complex#GO:0019005;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695 scaffold/adaptor protein#PC00226 HUMAN|HGNC=10289|UniProtKB=P27694 P27694 RPA1 PTHR23273:SF4 REPLICATION FACTOR A 1, RFA1 REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;damaged DNA binding#GO:0003684;telomeric DNA binding#GO:0042162;heterocyclic compound binding#GO:1901363 DNA repair#GO:0006281;telomere maintenance via telomere lengthening#GO:0010833;cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;telomere-telomerase complex assembly#GO:1905324;DNA geometric change#GO:0032392;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;reproductive process#GO:0022414;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;nucleotide-excision repair#GO:0006289;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;RNA-dependent DNA biosynthetic process#GO:0006278;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;reproduction#GO:0000003;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;cellular nitrogen compound biosynthetic process#GO:0044271;DNA duplex unwinding#GO:0032508;telomere maintenance via telomerase#GO:0007004;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;DNA unwinding involved in DNA replication#GO:0006268;homeostatic process#GO:0042592;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 pre-replicative complex#GO:0036387;intracellular membrane-bounded organelle#GO:0043231;epsilon DNA polymerase complex#GO:0008622;replisome#GO:0030894;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;chromosomal region#GO:0098687;replication fork#GO:0005657;membrane-enclosed lumen#GO:0031974;origin recognition complex#GO:0000808;nuclear chromosome, telomeric region#GO:0000784;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;DNA replication preinitiation complex#GO:0031261;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;CMG complex#GO:0071162;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;chromosome, telomeric region#GO:0000781;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 DNA metabolism protein#PC00009 HUMAN|HGNC=9792|UniProtKB=P51151 P51151 RAB9A PTHR47981:SF9 RAB FAMILY RAS-RELATED PROTEIN RAB-9A lysosome organization#GO:0007040;vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=20655|UniProtKB=Q8TEU7 Q8TEU7 RAPGEF6 PTHR23113:SF222 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=1051|UniProtKB=Q13323 Q13323 BIK PTHR15018:SF1 BCL-2-INTERACTING KILLER BCL-2-INTERACTING KILLER Apoptosis signaling pathway#P00006>Bik#P00258;Apoptosis signaling pathway#P00006>Blk#P00290 HUMAN|HGNC=17435|UniProtKB=Q9BXP2 Q9BXP2 SLC12A9 PTHR11827:SF98 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 9 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;chloride transport#GO:0006821;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;regulation of cellular component size#GO:0032535;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065 secondary carrier transporter#PC00258 HUMAN|HGNC=21399|UniProtKB=Q96NZ1 Q96NZ1 FOXN4 PTHR13962:SF17 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N4 HUMAN|HGNC=9466|UniProtKB=Q14558 Q14558 PRPSAP1 PTHR10210:SF28 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172 HUMAN|HGNC=7394|UniProtKB=P07438 P07438 MT1B PTHR23299:SF51 METALLOTHIONEIN METALLOTHIONEIN-1B cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;transition metal ion homeostasis#GO:0055076;response to metal ion#GO:0010038;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;response to toxic substance#GO:0009636;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9286|UniProtKB=Q13522 Q13522 PPP1R1A PTHR15417:SF4 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1A regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phosphatase inhibitor#PC00183 HUMAN|HGNC=8016|UniProtKB=P46459 P46459 NSF PTHR23078:SF3 VESICULAR-FUSION PROTEIN NSF VESICLE-FUSING ATPASE pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;organelle localization#GO:0051640;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Ionotropic glutamate receptor pathway#P00037>NSF#P01020;Synaptic vesicle trafficking#P05734>NSF#P05774 HUMAN|HGNC=31010|UniProtKB=Q2TAM9 Q2TAM9 TUSC1 PTHR34768:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 89 TUMOR SUPPRESSOR CANDIDATE GENE 1 PROTEIN HUMAN|HGNC=2678|UniProtKB=P14868 P14868 DARS1 PTHR43450:SF1 ASPARTYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a tRNA#GO:0140101;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=1507|UniProtKB=P55212 P55212 CASP6 PTHR10454:SF235 CASPASE CASPASE-6 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 Huntington disease#P00029>Caspase 6#P00809;FAS signaling pathway#P00020>Caspase6#P00596;FAS signaling pathway#P00020>Pro-Caspase6#P00607 HUMAN|HGNC=27723|UniProtKB=Q3SXM0 Q3SXM0 DCAF4L1 PTHR44472:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 4-LIKE PROTEIN 1 HUMAN|HGNC=3968|UniProtKB=Q92674 Q92674 CENPI PTHR48208:SF2 CENTROMERE PROTEIN I CENTROMERE PROTEIN I HUMAN|HGNC=25135|UniProtKB=Q6UWE0 Q6UWE0 LRSAM1 PTHR16083:SF39 LEUCINE RICH REPEAT CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE LRSAM1 HUMAN|HGNC=25840|UniProtKB=Q8N371 Q8N371 KDM8 PTHR12461:SF38 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND ARGINYL-HYDROXYLASE JMJD5 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 HUMAN|HGNC=4316|UniProtKB=Q92896 Q92896 GLG1 PTHR11884:SF1 SELECTIN LIGAND RELATED GOLGI APPARATUS PROTEIN 1 HUMAN|HGNC=10603|UniProtKB=O75880 O75880 SCO1 PTHR12151:SF4 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER PROTEIN SCO1 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 oxidase#PC00175 HUMAN|HGNC=29645|UniProtKB=Q9NXK6 Q9NXK6 PAQR5 PTHR20855:SF38 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR GAMMA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021 HUMAN|HGNC=19028|UniProtKB=Q9BRZ2 Q9BRZ2 TRIM56 PTHR25462:SF286 BONUS, ISOFORM C-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM56 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=25007|UniProtKB=Q8N3Z3 Q8N3Z3 GTPBP8 PTHR46498:SF1 GTP-BINDING PROTEIN 8 GTP-BINDING PROTEIN 8 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=173|UniProtKB=P27037 P27037 ACVR2A PTHR23255:SF64 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-2A signaling receptor activity#GO:0038023;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;activin binding#GO:0048185;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007 membrane protein complex#GO:0098796;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII#P06747;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII/IIB#P06780 HUMAN|HGNC=20873|UniProtKB=Q8NDP4 Q8NDP4 ZNF439 PTHR24381:SF244 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 20-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26101|UniProtKB=Q96CM8 Q96CM8 ACSF2 PTHR43201:SF9 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ligase#PC00142 HUMAN|HGNC=26407|UniProtKB=Q3MHD2 Q3MHD2 LSM12 PTHR13542:SF0 LSM12 HOMOLOG PROTEIN LSM12 HOMOLOG HUMAN|HGNC=23618|UniProtKB=Q6NV75 Q6NV75 GPR153 PTHR16518:SF5 G-PROTEIN COUPLED RECEPTOR 153, 162 G-PROTEIN COUPLED RECEPTOR 153-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=33999|UniProtKB=P0DN26 P0DN26 PPIAL4F PTHR11071:SF466 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A-LIKE 4C-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=9630|UniProtKB=P21246 P21246 PTN PTHR13850:SF1 PLEIOTROPHIN FAMILY MEMBER PLEIOTROPHIN binding#GO:0005488;receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 growth factor#PC00112 HUMAN|HGNC=6441|UniProtKB=P19013 P19013 KRT4 PTHR45616:SF3 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 4 HUMAN|HGNC=28479|UniProtKB=Q8WTQ4 Q8WTQ4 C16orf78 PTHR35679:SF1 RIKEN CDNA 4933402J07 GENE RIKEN CDNA 4933402J07 GENE HUMAN|HGNC=8280|UniProtKB=Q8NHB1 Q8NHB1 OR2V1 PTHR26453:SF271 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2V1 transmembrane signal receptor#PC00197 HUMAN|HGNC=4281|UniProtKB=P48165 P48165 GJA8 PTHR11984:SF19 CONNEXIN GAP JUNCTION ALPHA-8 PROTEIN gap junction#PC00105 HUMAN|HGNC=26056|UniProtKB=Q9NWW7 Q9NWW7 C2orf42 PTHR13518:SF1 PUTATIVE TREBLE-CLEF ZINC-FINGER C2ORF42 FAMILY MEMBER ZF-TCIX DOMAIN-CONTAINING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=14201|UniProtKB=Q9HDC5 Q9HDC5 JPH1 PTHR23085:SF6 GH28348P JUNCTOPHILIN-1 sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=13626|UniProtKB=P62955 P62955 CACNG7 PTHR12107:SF12 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-7 SUBUNIT calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;cation channel activity#GO:0005261;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 cellular localization#GO:0051641;membrane organization#GO:0061024;system process#GO:0003008;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;anterograde trans-synaptic signaling#GO:0098916;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;regulation of transmembrane transporter activity#GO:0022898;positive regulation of signaling#GO:0023056;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;establishment of protein localization to vacuole#GO:0072666;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;protein localization to synapse#GO:0035418;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of ion transmembrane transport#GO:0034765;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein localization to cell junction#GO:1902414;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;regulation of trans-synaptic signaling#GO:0099177;regulation of ion transport#GO:0043269;multicellular organismal process#GO:0032501;protein-containing complex localization#GO:0031503;receptor localization to synapse#GO:0097120;signal transduction#GO:0007165;regulation of neurotransmitter receptor activity#GO:0099601;receptor internalization#GO:0031623;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;action potential#GO:0001508;cation transport#GO:0006812;ionotropic glutamate receptor signaling pathway#GO:0035235;cation transmembrane transport#GO:0098655;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;vacuolar transport#GO:0007034;protein localization to membrane#GO:0072657;regulation of membrane potential#GO:0042391;protein localization to vacuole#GO:0072665;ion transport#GO:0006811;establishment of protein localization to organelle#GO:0072594;regulation of AMPA receptor activity#GO:2000311;nervous system process#GO:0050877;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;protein localization to cell periphery#GO:1990778;localization#GO:0051179;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of synaptic transmission#GO:0050806;synaptic transmission, glutamatergic#GO:0035249 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;organelle#GO:0043226;integral component of membrane#GO:0016021;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=6986|UniProtKB=Q16626 Q16626 MEA1 PTHR17005:SF3 MALE-ENHANCED ANTIGEN-1 MALE-ENHANCED ANTIGEN 1 HUMAN|HGNC=16950|UniProtKB=O95630 O95630 STAMBP PTHR12947:SF8 AMSH-LIKE PROTEASE STAM-BINDING PROTEIN thiol-dependent ubiquitin-specific protease activity#GO:0004843;hydrolase activity#GO:0016787;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein K63-linked deubiquitination#GO:0070536;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell division site#GO:0032153;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=8744|UniProtKB=P16519 P16519 PCSK2 PTHR42884:SF13 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 2 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;cell projection#GO:0042995;plasma membrane#GO:0005886 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 HUMAN|HGNC=17757|UniProtKB=Q9H2S6 Q9H2S6 TNMD PTHR14064:SF3 CHONDROMODULIN-RELATED TENOMODULIN negative regulation of cellular response to growth factor stimulus#GO:0090288;cell population proliferation#GO:0008283;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;epithelial cell proliferation#GO:0050673;regulation of cellular response to growth factor stimulus#GO:0090287;vasculature development#GO:0001944;negative regulation of cell communication#GO:0010648;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;tube development#GO:0035295;cell communication#GO:0007154;regulation of response to stimulus#GO:0048583;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;epithelium development#GO:0060429;regulation of anatomical structure morphogenesis#GO:0022603;regulation of signaling#GO:0023051;developmental process#GO:0032502;endothelial cell proliferation#GO:0001935;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;system development#GO:0048731;negative regulation of cell population proliferation#GO:0008285;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;cell morphogenesis involved in differentiation#GO:0000904;negative regulation of response to stimulus#GO:0048585;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;cell development#GO:0048468;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 HUMAN|HGNC=29332|UniProtKB=Q5T1S8 Q5T1S8 NCMAP PTHR35974:SF1 NONCOMPACT MYELIN-ASSOCIATED PROTEIN NONCOMPACT MYELIN-ASSOCIATED PROTEIN myelin protein#PC00161 HUMAN|HGNC=13486|UniProtKB=A6NNY8 A6NNY8 USP27X PTHR21646:SF30 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 27 cysteine protease#PC00081 HUMAN|HGNC=4288|UniProtKB=O95452 O95452 GJB6 PTHR11984:SF23 CONNEXIN GAP JUNCTION BETA-6 PROTEIN gap junction#PC00105 HUMAN|HGNC=5163|UniProtKB=Q92902 Q92902 HPS1 PTHR12761:SF1 HERMANSKY-PUDLAK SYNDROME PROTEIN 1 HERMANSKY-PUDLAK SYNDROME 1 PROTEIN GTPase binding#GO:0051020;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=34451|UniProtKB=Q6P0A1 Q6P0A1 FAM180B PTHR34034:SF1 PROTEIN FAM180A-RELATED PROTEIN FAM180B HUMAN|HGNC=9780|UniProtKB=Q8TBN0 Q8TBN0 RAB3IL1 PTHR14430:SF5 RABIN3-RELATED GUANINE NUCLEOTIDE EXCHANGE FACTOR FOR RAB-3A Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=10784|UniProtKB=Q99590 Q99590 SCAF11 PTHR47048:SF1 PROTEIN SCAF11 PROTEIN SCAF11 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 HUMAN|HGNC=4188|UniProtKB=O75600 O75600 GCAT PTHR13693:SF77 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL transaminase#PC00216 Biotin biosynthesis#P02731>8-Amino-7-oxononanoate synthase#P02858 HUMAN|HGNC=2893|UniProtKB=Q9UBP4 Q9UBP4 DKK3 PTHR12113:SF8 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=10447|UniProtKB=P10301 P10301 RRAS PTHR24070:SF245 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN R-RAS GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;EGF receptor signaling pathway#P00018>Ras#P00552;Integrin signalling pathway#P00034>Ras#P00916 HUMAN|HGNC=18355|UniProtKB=Q8N0X4 Q8N0X4 CLYBL PTHR11105:SF0 CITRATE LYASE SUBUNIT BETA-RELATED CITRAMALYL-COA LYASE, MITOCHONDRIAL lyase#PC00144 Pyruvate metabolism#P02772>Citrate Lyase#P03137 HUMAN|HGNC=13095|UniProtKB=P17041 P17041 ZNF32 PTHR23226:SF214 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 32 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25321|UniProtKB=Q9H0F6 Q9H0F6 SHARPIN PTHR22770:SF43 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED SHARPIN transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin binding#GO:0043130;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=33852|UniProtKB=P0CL83 P0CL83 STAG3L1 PTHR11199:SF8 STROMAL ANTIGEN COHESIN SUBUNIT SA-3-RELATED binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;chromatin#GO:0000785;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=26877|UniProtKB=Q8IYA6 Q8IYA6 CKAP2L PTHR47078:SF1 CYTOSKELETON-ASSOCIATED PROTEIN 2-LIKE CYTOSKELETON-ASSOCIATED PROTEIN 2-LIKE cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=31989|UniProtKB=P0C2Y1 P0C2Y1 NBPF7 PTHR14199:SF29 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 4-RELATED HUMAN|HGNC=9612|UniProtKB=Q14289 Q14289 PTK2B PTHR24418:SF94 TYROSINE-PROTEIN KINASE PROTEIN-TYROSINE KINASE 2-BETA synapse#GO:0045202;somatodendritic compartment#GO:0036477;anchoring junction#GO:0070161;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 Gonadotropin-releasing hormone receptor pathway#P06664>Pyk2#P06730;CCKR signaling map#P06959>FAK2#P07218;Integrin signalling pathway#P00034>FAK#P00932;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PYK2#P00852 HUMAN|HGNC=24176|UniProtKB=Q6UXG8 Q6UXG8 BTNL9 PTHR24100:SF117 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 9 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=26360|UniProtKB=Q8N7J2 Q8N7J2 AMER2 PTHR22237:SF1 UNCHARACTERIZED APC MEMBRANE RECRUITMENT PROTEIN 2 phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;beta-catenin binding#GO:0008013 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=12841|UniProtKB=P07947 P07947 YES1 PTHR24418:SF90 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE YES protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell population proliferation#GO:0008283;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;innate immune response#GO:0045087;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;peptidyl-tyrosine modification#GO:0018212;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 Cadherin signaling pathway#P00012>Yes#P00476;CCKR signaling map#P06959>YES1#P07142;Parkinson disease#P00049>Src kinase#P01230 HUMAN|Gene=ENH3_HUMAN|UniProtKB=Q9N2J8 Q9N2J8 - PTHR10424:SF60 VIRAL ENVELOPE PROTEIN HERV-H_2Q24.1 PROVIRUS ANCESTRAL ENV POLYPROTEIN-RELATED viral or transposable element protein#PC00237 HUMAN|HGNC=18079|UniProtKB=Q5T0B9 Q5T0B9 ZNF362 PTHR24390:SF96 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 362 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=10874|UniProtKB=O15389 O15389 SIGLEC5 PTHR12035:SF103 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 5 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=6263|UniProtKB=P63252 P63252 KCNJ2 PTHR11767:SF43 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=26179|UniProtKB=Q499Z4 Q499Z4 ZNF672 PTHR24408:SF54 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 316-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11067|UniProtKB=P82251 P82251 SLC7A9 PTHR11785:SF354 AMINO ACID TRANSPORTER B(0,+)-TYPE AMINO ACID TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 transporter#PC00227 HUMAN|HGNC=28783|UniProtKB=Q7Z7K0 Q7Z7K0 CMC1 PTHR22977:SF5 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN HOMOLOG cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18118|UniProtKB=Q96T23 Q96T23 RSF1 PTHR10615:SF204 HISTONE ACETYLTRANSFERASE REMODELING AND SPACING FACTOR 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;histone binding#GO:0042393;N-acyltransferase activity#GO:0016410;histone acetyltransferase activity#GO:0004402;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;peptide-lysine-N-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;protein binding#GO:0005515;molecular function regulator#GO:0098772;H4 histone acetyltransferase activity#GO:0010485 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=4259|UniProtKB=Q9UJ14 Q9UJ14 GGT7 PTHR11686:SF54 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 7 transferase activity, transferring acyl groups#GO:0016746;hydrolase activity#GO:0016787;transferase activity#GO:0016740;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190 HUMAN|HGNC=17037|UniProtKB=Q8WVM0 Q8WVM0 TFB1M PTHR11727:SF17 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL N-methyltransferase activity#GO:0008170;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;methyltransferase activity#GO:0008168;catalytic activity, acting on RNA#GO:0140098;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;RNA polymerase binding#GO:0070063;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;mitochondrial gene expression#GO:0140053;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;ncRNA metabolic process#GO:0034660;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;methylation#GO:0032259;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;aromatic compound biosynthetic process#GO:0019438;RNA methylation#GO:0001510 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 HUMAN|HGNC=2640|UniProtKB=P24462 P24462 CYP3A7 PTHR24302:SF31 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A7 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;oxidative demethylation#GO:0070989;oxidation-reduction process#GO:0055114;demethylation#GO:0070988;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177 HUMAN|HGNC=13900|UniProtKB=Q9HBY8 Q9HBY8 SGK2 PTHR24356:SF197 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE SGK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=1739|UniProtKB=O75419 O75419 CDC45 PTHR10507:SF0 CDC45-RELATED PROTEIN CELL DIVISION CONTROL PROTEIN 45 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;chromatin organization involved in negative regulation of transcription#GO:0097549;positive regulation of cell cycle G1/S phase transition#GO:1902808;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;gene silencing#GO:0016458;positive regulation of mitotic cell cycle#GO:0045931;regulation of chromatin organization#GO:1902275;regulation of G1/S transition of mitotic cell cycle#GO:2000045;protein-containing complex subunit organization#GO:0043933;cellular protein-containing complex assembly#GO:0034622;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;double-strand break repair via homologous recombination#GO:0000724;cell cycle phase transition#GO:0044770;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;mitotic DNA replication#GO:1902969;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cell cycle G1/S phase transition#GO:1902806;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;mitotic cell cycle phase transition#GO:0044772;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;organic cyclic compound metabolic process#GO:1901360;positive regulation of cell cycle process#GO:0090068;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;cell cycle DNA replication#GO:0044786;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;DNA-dependent DNA replication#GO:0006261;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;double-strand break repair via break-induced replication#GO:0000727;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;regulation of mitotic cell cycle#GO:0007346;negative regulation of gene expression#GO:0010629;DNA repair#GO:0006281;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;regulation of chromatin silencing#GO:0031935;regulation of RNA biosynthetic process#GO:2001141;protein-DNA complex assembly#GO:0065004;G1/S transition of mitotic cell cycle#GO:0000082;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of gene expression, epigenetic#GO:0040029;nuclear DNA replication#GO:0033260;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;RNA biosynthetic process#GO:0032774;chromatin silencing at telomere#GO:0006348;positive regulation of cellular process#GO:0048522;response to stress#GO:0006950;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication initiation#GO:0006270;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular biosynthetic process#GO:0031327;negative regulation of cellular metabolic process#GO:0031324;negative regulation of RNA biosynthetic process#GO:1902679;cell cycle G1/S phase transition#GO:0044843;protein-containing complex assembly#GO:0065003;mitotic cell cycle process#GO:1903047;regulation of transcription, DNA-templated#GO:0006355;regulation of gene expression#GO:0010468;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;negative regulation of gene expression, epigenetic#GO:0045814;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organelle fission#GO:0048285;DNA replication#GO:0006260;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;pre-replicative complex#GO:0036387;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 replication origin binding protein#PC00199 HUMAN|HGNC=13019|UniProtKB=Q9NYT6 Q9NYT6 ZNF226 PTHR24376:SF118 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 226 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3659|UniProtKB=Q99689 Q99689 FEZ1 PTHR12394:SF4 ZYGIN FASCICULATION AND ELONGATION PROTEIN ZETA-1 cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;axon#GO:0030424 HUMAN|HGNC=20437|UniProtKB=Q719I0 Q719I0 AHSA2P PTHR13009:SF4 HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1 ACTIVATOR OF 90 KDA HEAT SHOCK PROTEIN ATPASE HOMOLOG 2-RELATED pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;ATPase activator activity#GO:0001671;enzyme regulator activity#GO:0030234;ATPase activity#GO:0016887 regulation of molecular function#GO:0065009;protein folding#GO:0006457;positive regulation of catalytic activity#GO:0043085;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=28185|UniProtKB=Q9BRQ5 Q9BRQ5 ORAI3 PTHR31501:SF6 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 PROTEIN ORAI-3 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812;calcium ion transport#GO:0006816 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133 HUMAN|HGNC=29426|UniProtKB=Q6UXH8 Q6UXH8 CCBE1 PTHR24034:SF76 EGF-LIKE DOMAIN-CONTAINING PROTEIN COLLAGEN AND CALCIUM-BINDING EGF DOMAIN-CONTAINING PROTEIN 1 extracellular matrix structural protein#PC00103 HUMAN|HGNC=3246|UniProtKB=Q9NZC4 Q9NZC4 EHF PTHR11849:SF171 ETS ETS HOMOLOGOUS FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=33727|UniProtKB=Q658L1 Q658L1 SAXO2 PTHR31516:SF6 STABILIZER OF AXONEMAL MICROTUBULES 2 STABILIZER OF AXONEMAL MICROTUBULES 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;microtubule anchoring#GO:0034453;cellular process#GO:0009987 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;C2 axonemal microtubule#GO:1990720;B axonemal microtubule#GO:0097650;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;C1 axonemal microtubule#GO:1990719;microtubule organizing center#GO:0005815;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;centriole#GO:0005814;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;ciliary basal body#GO:0036064;axonemal central apparatus#GO:1990716;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;axonemal microtubule#GO:0005879 HUMAN|HGNC=24523|UniProtKB=Q8IYH5 Q8IYH5 ZZZ3 PTHR22705:SF0 ZINC FINGER, ZZ DOMAIN CONTAINING 3 ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3 peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;histone H4 acetylation#GO:0043967;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=8663|UniProtKB=Q9Y5I3 Q9Y5I3 PCDHA1 PTHR24028:SF92 CADHERIN-87A PROTOCADHERIN ALPHA-1 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=30782|UniProtKB=Q9BXJ9 Q9BXJ9 NAA15 PTHR22767:SF6 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 15, NATA AUXILIARY SUBUNIT transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;N-acyltransferase activity#GO:0016410 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;N-terminal protein amino acid acetylation#GO:0006474;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 acetyltransferase#PC00038 HUMAN|HGNC=1138|UniProtKB=O00481 O00481 BTN3A1 PTHR24100:SF128 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 3 MEMBER A1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=28773|UniProtKB=Q86V20 Q86V20 SHLD2 PTHR14495:SF2 SHIELDIN COMPLEX SUBUNIT 2 SHIELDIN COMPLEX SUBUNIT 2 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of double-strand break repair#GO:2000779;double-strand break repair#GO:0006302;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;regulation of DNA repair#GO:0006282;nucleobase-containing compound metabolic process#GO:0006139;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of DNA recombination#GO:0000018;regulation of metabolic process#GO:0019222;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9404|UniProtKB=P41743 P41743 PRKCI PTHR24356:SF214 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C IOTA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 HUMAN|HGNC=681|UniProtKB=Q92888 Q92888 ARHGEF1 PTHR45872:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoGEF#P00728;Axon guidance mediated by semaphorins#P00007>RhoGEF#P00333;Cytoskeletal regulation by Rho GTPase#P00016>Rho GEFs#P00518 HUMAN|HGNC=25365|UniProtKB=Q8WUF8 Q8WUF8 FAM172A PTHR21357:SF3 UNCHARACTERIZED COTRANSCRIPTIONAL REGULATOR FAM172A RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;heterochromatin organization#GO:0070828;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;heterochromatin assembly#GO:0031507;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11912|UniProtKB=Q92956 Q92956 TNFRSF14 PTHR46838:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14 positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of cytokine production involved in immune response#GO:0002718;positive regulation of protein modification process#GO:0031401;production of molecular mediator of immune response#GO:0002440;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;peptidyl-tyrosine phosphorylation#GO:0018108;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;leukocyte activation#GO:0045321;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell adhesion#GO:0007155;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of leukocyte activation#GO:0002695;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;defense response to Gram-negative bacterium#GO:0050829;cell activation#GO:0001775;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;cellular macromolecule metabolic process#GO:0044260;biological adhesion#GO:0022610;protein modification process#GO:0036211;leukocyte cell-cell adhesion#GO:0007159;cytokine production#GO:0001816;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of leukocyte migration#GO:0002687;T cell proliferation#GO:0042098;response to bacterium#GO:0009617;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;immune effector process#GO:0002252;negative regulation of cellular process#GO:0048523;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cell motility#GO:0048870;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;regulation of T cell proliferation#GO:0042129;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;positive regulation of cell migration#GO:0030335;regulation of mononuclear cell proliferation#GO:0032944;response to other organism#GO:0051707;regulation of lymphocyte proliferation#GO:0050670;negative regulation of lymphocyte activation#GO:0051250;response to external biotic stimulus#GO:0043207;regulation of protein modification process#GO:0031399;regulation of cell-cell adhesion#GO:0022407;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;positive regulation of cellular component movement#GO:0051272;regulation of phosphorus metabolic process#GO:0051174;regulation of cell activation#GO:0050865;leukocyte migration#GO:0050900;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;positive regulation of cytokine production#GO:0001819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;mononuclear cell proliferation#GO:0032943;organic substance metabolic process#GO:0071704;negative regulation of T cell proliferation#GO:0042130;negative regulation of T cell activation#GO:0050868;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of locomotion#GO:0040017;defense response to Gram-positive bacterium#GO:0050830;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;movement of cell or subcellular component#GO:0006928;regulation of production of molecular mediator of immune response#GO:0002700;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;negative regulation of cell-cell adhesion#GO:0022408;macromolecule modification#GO:0043412;peptidyl-amino acid modification#GO:0018193;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;negative regulation of cell population proliferation#GO:0008285;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;lymphocyte activation#GO:0046649;regulation of cell motility#GO:2000145;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;T cell activation#GO:0042110;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=317|UniProtKB=P02771 P02771 AFP PTHR11385:SF7 SERUM ALBUMIN-RELATED ALPHA-FETOPROTEIN cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;carboxylic acid binding#GO:0031406;metal ion binding#GO:0046872;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;intracellular#GO:0005622;extracellular region#GO:0005576 transfer/carrier protein#PC00219 HUMAN|HGNC=30668|UniProtKB=O60687 O60687 SRPX2 PTHR46343:SF3 FAMILY NOT NAMED SUSHI REPEAT-CONTAINING PROTEIN SRPX2 HUMAN|HGNC=9257|UniProtKB=Q08752 Q08752 PPID PTHR11071:SF510 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D chaperone#PC00072 HUMAN|HGNC=6954|UniProtKB=Q8NEM0 Q8NEM0 MCPH1 PTHR14625:SF3 MICROCEPHALIN MICROCEPHALIN cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 damaged DNA-binding protein#PC00086 HUMAN|HGNC=4424|UniProtKB=Q92805 Q92805 GOLGA1 PTHR23157:SF24 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GOLGIN SUBFAMILY A MEMBER 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=12866|UniProtKB=Q14590 Q14590 ZNF235 PTHR24377:SF954 IP01015P-RELATED ZINC FINGER PROTEIN 235 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24256|UniProtKB=Q9Y3C0 Q9Y3C0 WASHC3 PTHR13015:SF2 PROTEIN AD-016-RELATED WASH COMPLEX SUBUNIT 3 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;secretion#GO:0046903;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;vesicle organization#GO:0016050;cytoskeleton organization#GO:0007010;secretion by cell#GO:0032940;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;vesicle-mediated transport#GO:0016192;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036;export from cell#GO:0140352 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=29876|UniProtKB=Q9BWL3 Q9BWL3 C1orf43 PTHR21425:SF2 NICE-3 PROTEIN C1ORF43 HUMAN|HGNC=25419|UniProtKB=Q3SXY8 Q3SXY8 ARL13B PTHR46090:SF3 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B vesicle targeting, to, from or within Golgi#GO:0048199;non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 bounding membrane of organelle#GO:0098588;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;motile cilium#GO:0031514;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=25132|UniProtKB=Q96H15 Q96H15 TIMD4 PTHR46608:SF1 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=20065|UniProtKB=Q70CQ3 Q70CQ3 USP30 PTHR24006:SF650 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=10298|UniProtKB=P27635 P27635 RPL10 PTHR11726:SF36 60S RIBOSOMAL PROTEIN L10 60S RIBOSOMAL PROTEIN L10 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=14263|UniProtKB=Q9ULC3 Q9ULC3 RAB23 PTHR24073:SF209 DRAB5-RELATED RAS-RELATED PROTEIN RAB-23 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;process utilizing autophagic mechanism#GO:0061919;amide transport#GO:0042886;organic substance transport#GO:0071702;vacuole organization#GO:0007033;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;autophagosome organization#GO:1905037;establishment of localization in cell#GO:0051649;autophagosome assembly#GO:0000045;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;autophagosome#GO:0005776;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=1260|UniProtKB=O43822 O43822 CFAP410 PTHR18849:SF0 LEUCINE RICH REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410 HUMAN|HGNC=539|UniProtKB=A6NMY6 A6NMY6 ANXA2P2 PTHR10502:SF18 ANNEXIN ANNEXIN A2-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calcium-binding protein#PC00060 HUMAN|HGNC=21581|UniProtKB=Q5VZK9 Q5VZK9 CARMIL1 PTHR24112:SF39 LEUCINE-RICH REPEAT, ISOFORM F-RELATED F-ACTIN-UNCAPPING PROTEIN LRRC16A HUMAN|HGNC=12178|UniProtKB=A0A0K0K1G8 A0A0K0K1G8 TRBV10-2 PTHR23268:SF80 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 10-1-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=11163|UniProtKB=P62308 P62308 SNRPG PTHR10553:SF26 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;SMN complex#GO:0032797;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974;U12-type spliceosomal complex#GO:0005689;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;catalytic complex#GO:1902494;U1 snRNP#GO:0005685;U4 snRNP#GO:0005687;U5 snRNP#GO:0005682;cytoplasmic ribonucleoprotein granule#GO:0036464;SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 HUMAN|HGNC=1600|UniProtKB=O60583 O60583 CCNT2 PTHR10026:SF43 CYCLIN CYCLIN-T2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of DNA-templated transcription, elongation#GO:0032784;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 kinase activator#PC00138 HUMAN|HGNC=8607|UniProtKB=O60260 O60260 PRKN PTHR11685:SF385 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE PARKIN ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Parkin#P01216 HUMAN|HGNC=6345|UniProtKB=Q13351 Q13351 KLF1 PTHR23235:SF41 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=17621|UniProtKB=Q8NFP7 Q8NFP7 NUDT10 PTHR12629:SF43 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 3-ALPHA pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleotide diphosphatase activity#GO:0004551;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organophosphate catabolic process#GO:0046434;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphatase#PC00181 HUMAN|HGNC=10864|UniProtKB=Q11206 Q11206 ST3GAL4 PTHR13713:SF57 SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 4 transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=3586|UniProtKB=Q9HB96 Q9HB96 FANCE PTHR32094:SF5 FANCONI ANEMIA GROUP E PROTEIN FANCONI ANEMIA GROUP E PROTEIN membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;Fanconi anaemia nuclear complex#GO:0043240;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=19179|UniProtKB=Q8IZV2 Q8IZV2 CMTM8 PTHR22776:SF10 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 8 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=20961|UniProtKB=Q92625 Q92625 ANKS1A PTHR24174:SF4 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 1A cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18803|UniProtKB=Q5TC12 Q5TC12 ATPAF1 PTHR13126:SF0 CHAPERONE ATP11 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=6047|UniProtKB=Q16891 Q16891 IMMT PTHR15415:SF7 MITOFILIN MICOS COMPLEX SUBUNIT MIC60 cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;membrane organization#GO:0061024;organelle organization#GO:0006996;anatomical structure development#GO:0048856;developmental process#GO:0032502;cristae formation#GO:0042407;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;cell part morphogenesis#GO:0032990;cellular component morphogenesis#GO:0032989;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=19897|UniProtKB=Q96KE9 Q96KE9 BTBD6 PTHR45774:SF5 BTB/POZ DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN 6 cellular developmental process#GO:0048869;system development#GO:0048731;cell differentiation#GO:0030154;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cellular process#GO:0009987;nervous system development#GO:0007399 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=28894|UniProtKB=Q6K0P9 Q6K0P9 PYHIN1 PTHR12200:SF25 INTERFERON-INDUCIBLE PROTEIN AIM2 FAMILY MEMBER PYRIN AND HIN DOMAIN-CONTAINING PROTEIN 1 heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;activation of immune response#GO:0002253;response to cytokine#GO:0034097;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;positive regulation of metabolic process#GO:0009893;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;defense response to other organism#GO:0098542;response to chemical#GO:0042221;activation of innate immune response#GO:0002218;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of defense response#GO:0031347;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=2332|UniProtKB=Q8N123 Q8N123 CPXCR1 PTHR42213:SF1 CPX CHROMOSOMAL REGION CANDIDATE GENE 1 PROTEIN CPX CHROMOSOMAL REGION CANDIDATE GENE 1 PROTEIN HUMAN|HGNC=30404|UniProtKB=Q96GA7 Q96GA7 SDSL PTHR48078:SF16 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED SERINE DEHYDRATASE-LIKE lyase activity#GO:0016829;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 dehydratase#PC00091 HUMAN|HGNC=29285|UniProtKB=Q6VN20 Q6VN20 RANBP10 PTHR12864:SF19 RAN BINDING PROTEIN 9-RELATED RAN-BINDING PROTEIN 10 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=13634|UniProtKB=Q969L2 Q969L2 MAL2 PTHR22776:SF42 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN PROTEIN MAL2 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=3574|UniProtKB=O60427 O60427 FADS1 PTHR19353:SF57 FATTY ACID DESATURASE 2 ACYL-COA (8-3)-DESATURASE HUMAN|HGNC=28379|UniProtKB=Q8TBF8 Q8TBF8 FAM81A PTHR22420:SF2 UNCHARACTERIZED PROTEIN FAM81A HUMAN|HGNC=20799|UniProtKB=Q76EJ3 Q76EJ3 SLC35D2 PTHR11132:SF262 SOLUTE CARRIER FAMILY 35 UDP-N-ACETYLGLUCOSAMINE/UDP-GLUCOSE/GDP-MANNOSE TRANSPORTER secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=12461|UniProtKB=Q9NZ09 Q9NZ09 UBAP1 PTHR15960:SF2 LD44032P UBIQUITIN-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 protein catabolic process in the vacuole#GO:0007039;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;localization#GO:0051179;modification-dependent macromolecule catabolic process#GO:0043632;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=28330|UniProtKB=Q8TBQ9 Q8TBQ9 TMEM167A PTHR13229:SF17 PROTEIN KISH-A PROTEIN KISH-A cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;peptide secretion#GO:0002790;cellular process#GO:0009987;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 HUMAN|HGNC=27025|UniProtKB=Q8N1A6 Q8N1A6 C4orf33 PTHR31475:SF3 UPF0462 PROTEIN UPF0462 PROTEIN C4ORF33 HUMAN|HGNC=26392|UniProtKB=Q96NR3 Q96NR3 PTCHD1 PTHR10796:SF36 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 1 chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;cognition#GO:0050890;system process#GO:0003008;trans-synaptic signaling#GO:0099537;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095 HUMAN|HGNC=19263|UniProtKB=Q9H0V9 Q9H0V9 LMAN2L PTHR12223:SF20 VESICULAR MANNOSE-BINDING LECTIN VIP36-LIKE PROTEIN carbohydrate binding#GO:0030246;small molecule binding#GO:0036094;binding#GO:0005488 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;Golgi organization#GO:0007030;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 HUMAN|HGNC=11060|UniProtKB=P52569 P52569 SLC7A2 PTHR43243:SF35 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;L-lysine transmembrane transporter activity#GO:0015189;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;basic amino acid transmembrane transporter activity#GO:0015174;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;basic amino acid transmembrane transport#GO:1990822;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;basic amino acid transport#GO:0015802;L-alpha-amino acid transmembrane transport#GO:1902475;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046 HUMAN|HGNC=20844|UniProtKB=Q8NFN8 Q8NFN8 GPR156 PTHR10519:SF63 GABA-B RECEPTOR G-PROTEIN COUPLED RECEPTOR 156-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=16667|UniProtKB=Q9NV96 Q9NV96 TMEM30A PTHR10926:SF17 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50A organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=249|UniProtKB=P07327 P07327 ADH1A PTHR43880:SF1 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE 1A cation binding#GO:0043169;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 response to organic substance#GO:0010033;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=25881|UniProtKB=Q8TBM8 Q8TBM8 DNAJB14 PTHR43908:SF4 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY B MEMBER 14 heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488;Hsp70 protein binding#GO:0030544 cellular response to misfolded protein#GO:0071218;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;chaperone-mediated protein folding#GO:0061077;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;cellular protein catabolic process#GO:0044257;response to topologically incorrect protein#GO:0035966;'de novo' protein folding#GO:0006458;ubiquitin-dependent ERAD pathway#GO:0030433;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=30181|UniProtKB=Q9BWC9 Q9BWC9 CCDC106 PTHR16477:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 106 COILED-COIL DOMAIN-CONTAINING PROTEIN 106 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25150|UniProtKB=Q6NUJ5 Q6NUJ5 PWWP2B PTHR23068:SF6 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED PWWP DOMAIN-CONTAINING PROTEIN 2B DNA methyltransferase#PC00013 HUMAN|HGNC=2631|UniProtKB=P05181 P05181 CYP2E1 PTHR24300:SF356 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2E1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=4543|UniProtKB=P32298 P32298 GRK4 PTHR24355:SF14 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 4 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 HUMAN|HGNC=24748|UniProtKB=Q68D51 Q68D51 DENND2C PTHR15288:SF6 SUPPRESSION OF TUMORIGENICITY 5 ST5 DENN DOMAIN-CONTAINING PROTEIN 2C Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;Rab GTPase binding#GO:0017137;guanyl-nucleotide exchange factor activity#GO:0005085 HUMAN|HGNC=7219|UniProtKB=Q00013 Q00013 MPP1 PTHR23122:SF37 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK 55 KDA ERYTHROCYTE MEMBRANE PROTEIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=14423|UniProtKB=Q9NYR8 Q9NYR8 RDH8 PTHR43391:SF8 RETINOL DEHYDROGENASE-RELATED RETINOL DEHYDROGENASE 8 dehydrogenase#PC00092 HUMAN|HGNC=26310|UniProtKB=A0AUZ9 A0AUZ9 KANSL1L PTHR22443:SF16 NON-SPECIFIC LETHAL 1, ISOFORM M KAT8 REGULATORY NSL COMPLEX SUBUNIT 1-LIKE PROTEIN transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;protein binding#GO:0005515;H4 histone acetyltransferase activity#GO:0010485;N-acyltransferase activity#GO:0016410 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=11762|UniProtKB=Q9UP52 Q9UP52 TFR2 PTHR10404:SF33 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE TRANSFERRIN RECEPTOR PROTEIN 2 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;cation transport#GO:0006812;cellular homeostasis#GO:0019725;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;iron ion homeostasis#GO:0055072;vesicle organization#GO:0016050;iron ion transport#GO:0006826;receptor-mediated endocytosis#GO:0006898;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transition metal ion homeostasis#GO:0055076;iron import into cell#GO:0033212;ion transport#GO:0006811;endocytosis#GO:0006897;homeostatic process#GO:0042592;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular iron ion homeostasis#GO:0006879;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=4136|UniProtKB=Q14353 Q14353 GAMT PTHR32379:SF1 GUANIDINOACETATE N-METHYLTRANSFERASE GUANIDINOACETATE N-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 methyltransferase#PC00155 HUMAN|HGNC=10790|UniProtKB=Q12872 Q12872 SFSWAP PTHR13161:SF15 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT SPLICING FACTOR, SUPPRESSOR OF WHITE-APRICOT HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 RNA splicing factor#PC00148 HUMAN|Gene=HV309_HUMAN|UniProtKB=P01782 P01782 IGHV3-9 PTHR23266:SF324 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-9 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=19035|UniProtKB=Q6P0Q8 Q6P0Q8 MAST2 PTHR24356:SF136 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE/THREONINE-PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=11367|UniProtKB=P51692 P51692 STAT5B PTHR11801:SF39 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;defense response#GO:0006952;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;response to peptide hormone#GO:0043434;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;regulation of transcription, DNA-templated#GO:0006355;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;organic cyclic compound biosynthetic process#GO:1901362;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>STAT#P01173;JAK/STAT signaling pathway#P00038>STAT#P01027;Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561 HUMAN|Gene=YS049_HUMAN|UniProtKB=Q8WTZ3 Q8WTZ3 - PTHR12138:SF128 PRIMATE-EXPANDED PROTEIN FAMILY ZINC FINGER PROTEIN ENSP00000375192 HUMAN|HGNC=33177|UniProtKB=Q5MJ08 Q5MJ08 SPANXN4 PTHR23425:SF2 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME N4 HUMAN|HGNC=10869|UniProtKB=Q92185 Q92185 ST8SIA1 PTHR11987:SF3 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-N-ACETYLNEURAMINIDE ALPHA-2,8-SIALYLTRANSFERASE transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=19898|UniProtKB=Q7L1S5 Q7L1S5 CHST9 PTHR12137:SF6 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 9 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=6298|UniProtKB=P56696 P56696 KCNQ4 PTHR11537:SF4 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;calmodulin binding#GO:0005516;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=1486|UniProtKB=O14815 O14815 CAPN9 PTHR10183:SF385 CALPAIN CALPAIN-9 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=33106|UniProtKB=Q68DY9 Q68DY9 ZNF772 PTHR24377:SF610 IP01015P-RELATED ZINC FINGER PROTEIN 772 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8134|UniProtKB=Q99983 Q99983 OMD PTHR45712:SF3 AGAP008170-PA OSTEOMODULIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=17002|UniProtKB=Q8N2W9 Q8N2W9 PIAS4 PTHR10782:SF9 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS4 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;RNA polymerase II transcription factor binding#GO:0001085;molecular function regulator#GO:0098772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;transcription factor binding#GO:0008134 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 JAK/STAT signaling pathway#P00038>PIAS#P01031;Interferon-gamma signaling pathway#P00035>PIAS#P00958 HUMAN|HGNC=26787|UniProtKB=Q8N8X9 Q8N8X9 MAB21L3 PTHR10656:SF30 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 3 HUMAN|HGNC=23698|UniProtKB=Q8IVF7 Q8IVF7 FMNL3 PTHR45857:SF3 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;localization of cell#GO:0051674;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;anatomical structure development#GO:0048856;regulation of cell morphogenesis#GO:0022604;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=6443|UniProtKB=P02538 P02538 KRT6A PTHR45616:SF39 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 6A-RELATED HUMAN|HGNC=33760|UniProtKB=Q6PEX3 Q6PEX3 KRTAP26-1 PTHR19051:SF6 KERATIN-ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 26-1 structural protein#PC00211 HUMAN|HGNC=15958|UniProtKB=Q9H114 Q9H114 CSTL1 PTHR47887:SF1 CYSTATIN-LIKE 1 CYSTATIN-LIKE 1 HUMAN|HGNC=15844|UniProtKB=Q9NQG7 Q9NQG7 HPS4 PTHR14407:SF9 HERMANSKY-PUDLAK SYNDROME 4 PROTEIN LIGHT-EAR PROTEIN-RELATED HERMANSKY-PUDLAK SYNDROME 4 PROTEIN Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;pigmentation#GO:0043473;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;melanosome organization#GO:0032438;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=15677|UniProtKB=Q9H2K2 Q9H2K2 TNKS2 PTHR24180:SF11 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-2 transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;telomere capping#GO:0016233;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule localization#GO:0033036;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;telomere organization#GO:0032200;cellular protein localization#GO:0034613;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of Wnt signaling pathway#GO:0030177;telomere maintenance#GO:0000723;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;anatomical structure homeostasis#GO:0060249;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase inhibitor#PC00139 HUMAN|HGNC=30377|UniProtKB=Q14160 Q14160 SCRIB PTHR23119:SF44 DISCS LARGE PROTEIN SCRIBBLE HOMOLOG establishment or maintenance of cell polarity#GO:0007163;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;multicellular organismal process#GO:0032501;establishment or maintenance of apical/basal cell polarity#GO:0035088;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 membrane protein complex#GO:0098796;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;adherens junction#GO:0005912;intrinsic component of plasma membrane#GO:0031226;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18374|UniProtKB=Q8WWQ2 Q8WWQ2 HPSE2 PTHR46145:SF1 HEPARANASE INACTIVE HEPARANASE-2 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110 HUMAN|HGNC=5022|UniProtKB=Q9Y261 Q9Y261 FOXA2 PTHR11829:SF167 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=14923|UniProtKB=O60883 O60883 GPR37L1 PTHR46216:SF4 PROSAPOSIN RECEPTOR GPR37 FAMILY MEMBER G-PROTEIN COUPLED RECEPTOR 37-LIKE 1 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of MAPK cascade#GO:0043408;regulation of adenylate cyclase activity#GO:0045761;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;cAMP-mediated signaling#GO:0019933;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;second-messenger-mediated signaling#GO:0019932;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;regulation of cyclase activity#GO:0031279;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;negative regulation of response to stimulus#GO:0048585;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;negative regulation of cAMP-mediated signaling#GO:0043951;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;negative regulation of catalytic activity#GO:0043086;cyclic-nucleotide-mediated signaling#GO:0019935;negative regulation of molecular function#GO:0044092 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Parkinson disease#P00049>Pael-R#P01229 HUMAN|HGNC=27938|UniProtKB=A6NJV1 A6NJV1 FAM166C PTHR34924:SF1 UPF0573 PROTEIN C2ORF70 PROTEIN FAM166C HUMAN|Ensembl=ENSG00000269226|UniProtKB=A0A087X1C1 A0A087X1C1 TMSB15B PTHR12021:SF21 THYMOSIN BETA THYMOSIN BETA-15B cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;cellular protein localization#GO:0034613;protein-containing complex assembly#GO:0065003;regulation of localization#GO:0032879;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;regulation of cellular component movement#GO:0051270;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of cell motility#GO:2000145;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;localization of cell#GO:0051674;actin polymerization or depolymerization#GO:0008154;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=24692|UniProtKB=Q8WWV6 Q8WWV6 FCAMR PTHR11860:SF49 POLYMERIC-IMMUNOGLOBULIN RECEPTOR HIGH AFFINITY IMMUNOGLOBULIN ALPHA AND IMMUNOGLOBULIN MU FC RECEPTOR immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=6367|UniProtKB=Q92876 Q92876 KLK6 PTHR24271:SF19 KALLIKREIN-RELATED KALLIKREIN-6 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=24284|UniProtKB=Q8WVT3 Q8WVT3 TRAPPC12 PTHR21581:SF6 D-ALANYL-D-ALANINE CARBOXYPEPTIDASE TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203 HUMAN|HGNC=4572|UniProtKB=P42262 P42262 GRIA2 PTHR18966:SF99 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 2 amino acid binding#GO:0016597;cation channel activity#GO:0005261;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;glutamate binding#GO:0016595;ligand-gated channel activity#GO:0022834 membrane protein complex#GO:0098796;synapse#GO:0045202;somatodendritic compartment#GO:0036477;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;cell periphery#GO:0071944;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;postsynapse#GO:0098794;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>Glu2#P01017;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019 HUMAN|HGNC=25209|UniProtKB=Q8WUY3 Q8WUY3 PRUNE2 PTHR12112:SF11 BNIP - RELATED PROTEIN PRUNE HOMOLOG 2 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;phosphorus metabolic process#GO:0006793;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=5292|UniProtKB=P30939 P30939 HTR1F PTHR24247:SF34 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1F cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;negative regulation of biological process#GO:0048519;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;negative regulation of intracellular signal transduction#GO:1902532;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;negative regulation of catalytic activity#GO:0043086;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935;negative regulation of molecular function#GO:0044092 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 HUMAN|HGNC=19160|UniProtKB=Q9H6R6 Q9H6R6 ZDHHC6 PTHR22883:SF35 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC6 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=4847|UniProtKB=O43612 O43612 HCRT PTHR15173:SF2 OREXIN OREXIN HUMAN|HGNC=12628|UniProtKB=P45974 P45974 USP5 PTHR24006:SF655 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=16787|UniProtKB=Q9BZQ6 Q9BZQ6 EDEM3 PTHR45679:SF2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 3 HUMAN|HGNC=30438|UniProtKB=Q8IYB1 Q8IYB1 MB21D2 PTHR10656:SF47 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MB21D2 HUMAN|HGNC=1101|UniProtKB=P51587 P51587 BRCA2 PTHR11289:SF0 BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2 BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;regulation of RNA metabolic process#GO:0051252;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;cellular response to stress#GO:0033554;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 damaged DNA-binding protein#PC00086 HUMAN|HGNC=1863|UniProtKB=P23141 P23141 CES1 PTHR11559:SF179 CARBOXYLESTERASE LIVER CARBOXYLESTERASE 1-RELATED hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 esterase#PC00097 HUMAN|HGNC=26935|UniProtKB=Q9Y3I0 Q9Y3I0 RTCB PTHR11118:SF1 UNCHARACTERIZED RNA-SPLICING LIGASE RTCB HOMOLOG catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA replication#P00017>RFC#P00529 HUMAN|HGNC=7456|UniProtKB=P03891 P03891 MT-ND2 PTHR46552:SF1 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2 oxidoreductase#PC00176 HUMAN|HGNC=28602|UniProtKB=Q7L0X2 Q7L0X2 ERICH6 PTHR23093:SF11 SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 GLUTAMATE-RICH PROTEIN 6 HUMAN|HGNC=8484|UniProtKB=Q15617 Q15617 OR8G1 PTHR48018:SF56 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8G1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=2734|UniProtKB=Q92499 Q92499 DDX1 PTHR24031:SF307 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX1 HUMAN|HGNC=34518|UniProtKB=Q96AW1 Q96AW1 VOPP1 PTHR14971:SF2 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1 intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;integral component of membrane#GO:0016021;integral component of organelle membrane#GO:0031301 HUMAN|HGNC=16286|UniProtKB=Q92556 Q92556 ELMO1 PTHR12771:SF23 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 1 Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;locomotion#GO:0040011 cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>ELMO#P00917 HUMAN|HGNC=992|UniProtKB=Q07817 Q07817 BCL2L1 PTHR11256:SF12 BCL-2 RELATED BCL-2-LIKE PROTEIN 1 identical protein binding#GO:0042802;protein binding#GO:0005515;protein homodimerization activity#GO:0042803;binding#GO:0005488 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;cell death#GO:0008219;intracellular signal transduction#GO:0035556;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;negative regulation of cell death#GO:0060548;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of intrinsic apoptotic signaling pathway#GO:2001242;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 p53 pathway#P00059>BAX#G01581;Apoptosis signaling pathway#P00006>Bcl-xS#P00323;Apoptosis signaling pathway#P00006>Bcl-xL#P00257;Apoptosis signaling pathway#P00006>Bax#P00271;Huntington disease#P00029>Bax#G01533;CCKR signaling map#P06959>BCL2L1#P07117 HUMAN|HGNC=21394|UniProtKB=Q9NQ25 Q9NQ25 SLAMF7 PTHR12080:SF46 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 7 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=11799|UniProtKB=P10828 P10828 THRB PTHR24082:SF210 NUCLEAR HORMONE RECEPTOR THYROID HORMONE RECEPTOR BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=31791|UniProtKB=Q6ZT52 Q6ZT52 FAM43B PTHR11232:SF34 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN FAM43B scaffold/adaptor protein#PC00226 HUMAN|HGNC=25581|UniProtKB=A0AVT1 A0AVT1 UBA6 PTHR10953:SF186 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 6 ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 HUMAN|HGNC=30595|UniProtKB=Q6ZMI0 Q6ZMI0 PPP1R21 PTHR21448:SF0 SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21 HUMAN|HGNC=8028|UniProtKB=P78549 P78549 NTHL1 PTHR43286:SF1 ENDONUCLEASE III-LIKE PROTEIN 1 ENDONUCLEASE III-LIKE PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleotide-excision repair, DNA incision#GO:0033683;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704 DNA glycosylase#PC00010 HUMAN|HGNC=14217|UniProtKB=Q9NY57 Q9NY57 STK32B PTHR24356:SF157 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE 32B transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=24027|UniProtKB=Q8TDG2 Q8TDG2 ACTRT1 PTHR11937:SF153 ACTIN ACTIN-RELATED PROTEIN T1 binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 actin and actin related protein#PC00039 HUMAN|HGNC=13940|UniProtKB=Q9Y333 Q9Y333 LSM2 PTHR13829:SF2 SNRNP CORE PROTEIN FAMILY MEMBER U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 supramolecular complex#GO:0099080;catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;P-body#GO:0000932;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974 RNA splicing factor#PC00148 HUMAN|HGNC=25127|UniProtKB=Q8WVV9 Q8WVV9 HNRNPLL PTHR15592:SF13 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L-LIKE RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11355|UniProtKB=Q8N3U4 Q8N3U4 STAG2 PTHR11199:SF3 STROMAL ANTIGEN COHESIN SUBUNIT SA-2 binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;chromatin#GO:0000785;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=10997|UniProtKB=Q5K4L6 Q5K4L6 SLC27A3 PTHR43107:SF12 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN SOLUTE CARRIER FAMILY 27 MEMBER 3 ligase activity#GO:0016874;transporter activity#GO:0005215;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=15251|UniProtKB=Q8NH90 Q8NH90 OR5AK2 PTHR48018:SF179 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AK2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=9361|UniProtKB=P10124 P10124 SRGN PTHR17178:SF0 SECRETORY GRANULE PROTEOGLYCAN CORE PROTEIN SERGLYCIN HUMAN|HGNC=20792|UniProtKB=Q9BS91 Q9BS91 SLC35A5 PTHR10231:SF90 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-SUGAR TRANSPORTER PROTEIN SLC35A5-RELATED bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=20707|UniProtKB=Q96PE5 Q96PE5 OPALIN PTHR21102:SF0 OPALIN OPALIN cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cell-cell contact zone#GO:0044291;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|Ensembl=ENSG00000234719|UniProtKB=A6NJ64 A6NJ64 NPIPB2 PTHR15438:SF14 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER A1-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25902|UniProtKB=Q8NAT1 Q8NAT1 POMGNT2 PTHR20961:SF105 GLYCOSYLTRANSFERASE PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=904|UniProtKB=Q9Y2T1 Q9Y2T1 AXIN2 PTHR46102:SF1 AXIN AXIN-2 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Axin#P01429 HUMAN|HGNC=14521|UniProtKB=Q8N831 Q8N831 TSPYL6 PTHR11875:SF29 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 6 protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=19954|UniProtKB=Q9H936 Q9H936 SLC25A22 PTHR45678:SF3 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED MITOCHONDRIAL GLUTAMATE CARRIER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 dicarboxylic acid transport#GO:0006835;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;electron transport chain#GO:0022900;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;anion transport#GO:0006820;respiratory electron transport chain#GO:0022904;oxidation-reduction process#GO:0055114;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152;cellular respiration#GO:0045333;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;generation of precursor metabolites and energy#GO:0006091;ion transport#GO:0006811;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;mitochondrial transport#GO:0006839;localization#GO:0051179;C4-dicarboxylate transport#GO:0015740;organic acid transmembrane transport#GO:1903825 secondary carrier transporter#PC00258 HUMAN|HGNC=29479|UniProtKB=Q9BS16 Q9BS16 CENPK PTHR14401:SF6 CENTROMERE PROTEIN K CENTROMERE PROTEIN K nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;mitotic sister chromatid segregation#GO:0000070 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;condensed nuclear chromosome kinetochore#GO:0000778;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 HUMAN|HGNC=20389|UniProtKB=Q9HD89 Q9HD89 RETN PTHR21101:SF11 RESISTIN RESISTIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=26948|UniProtKB=Q5T013 Q5T013 HYI PTHR43489:SF6 ISOMERASE HYDROXYPYRUVATE ISOMERASE-RELATED isomerase#PC00135 HUMAN|HGNC=25535|UniProtKB=Q9NVV0 Q9NVV0 TMEM38B PTHR12454:SF5 TRIMERIC INTRACELLULAR CATION CHANNEL TRIMERIC INTRACELLULAR CATION CHANNEL TYPE B ion channel#PC00133 HUMAN|HGNC=6509|UniProtKB=Q9NS86 Q9NS86 LANCL2 PTHR12736:SF11 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=7533|UniProtKB=P20592 P20592 MX2 PTHR11566:SF46 DYNAMIN INTERFERON-INDUCED GTP-BINDING PROTEIN MX2 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;membrane organization#GO:0061024;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;membrane fission#GO:0090148;vesicle localization#GO:0051648;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;protein transport#GO:0015031;biological regulation#GO:0065007;protein polymerization#GO:0051258;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;regulation of synapse structure or activity#GO:0050803;mitochondrial fission#GO:0000266;vesicle-mediated transport in synapse#GO:0099003;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;non-membrane-bounded organelle#GO:0043228;membrane coat#GO:0030117;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;mitochondrial envelope#GO:0005740;plasma membrane region#GO:0098590;postsynapse#GO:0098794;coated membrane#GO:0048475;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;envelope#GO:0031975;membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;intracellular vesicle#GO:0097708;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;mitochondrion#GO:0005739;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=2521|UniProtKB=P17538 P17538 CTRB1 PTHR24250:SF52 CHYMOTRYPSIN-RELATED CHYMOTRYPSINOGEN B serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203 HUMAN|HGNC=78|UniProtKB=O14639 O14639 ABLIM1 PTHR24213:SF18 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 Axon guidance mediated by netrin#P00009>Ablim#P00358 HUMAN|HGNC=17241|UniProtKB=O95361 O95361 TRIM16 PTHR25465:SF10 FAMILY NOT NAMED TRIPARTITE MOTIF-CONTAINING PROTEIN 16-RELATED HUMAN|HGNC=11699|UniProtKB=Q13530 Q13530 SERINC3 PTHR10383:SF51 SERINE INCORPORATOR SERINE INCORPORATOR 3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 HUMAN|HGNC=18301|UniProtKB=Q8TDB8 Q8TDB8 SLC2A14 PTHR23503:SF53 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 14 HUMAN|HGNC=7132|UniProtKB=Q03164 Q03164 KMT2A PTHR45838:SF2 HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER HISTONE-LYSINE N-METHYLTRANSFERASE 2A N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;histone methylation#GO:0016571;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein alkylation#GO:0008213;protein methylation#GO:0006479;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone H3-K4 methylation#GO:0051568;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;histone lysine methylation#GO:0034968;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=11812|UniProtKB=O15164 O15164 TRIM24 PTHR45915:SF4 TRANSCRIPTION INTERMEDIARY FACTOR TRANSCRIPTION INTERMEDIARY FACTOR 1-ALPHA membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=6614|UniProtKB=P53671 P53671 LIMK2 PTHR46485:SF1 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=19650|UniProtKB=O43529 O43529 CHST10 PTHR12137:SF2 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 10 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=8602|UniProtKB=Q13219 Q13219 PAPPA PTHR46130:SF2 LAMGL DOMAIN-CONTAINING PROTEIN PAPPALYSIN-1 HUMAN|HGNC=10985|UniProtKB=Q9Y619 Q9Y619 SLC25A15 PTHR45624:SF22 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL ORNITHINE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 transporter#PC00227 HUMAN|HGNC=20369|UniProtKB=Q9H4X1 Q9H4X1 RGCC PTHR32193:SF3 REGULATOR OF CELL CYCLE RGCC REGULATOR OF CELL CYCLE RGCC HUMAN|HGNC=3081|UniProtKB=Q96PT4 Q96PT4 DUX3 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=24520|UniProtKB=Q8NCA5 Q8NCA5 FAM98A PTHR31353:SF9 FAM98 PROTEIN FAM98A protein-containing complex#GO:0032991;intracellular#GO:0005622 RNA splicing factor#PC00148 HUMAN|HGNC=2456|UniProtKB=Q9Y6M4 Q9Y6M4 CSNK1G3 PTHR11909:SF151 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;membrane organization#GO:0061024;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of Wnt signaling pathway#GO:0030177;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;vesicle organization#GO:0016050;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;localization#GO:0051179;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 HUMAN|HGNC=8904|UniProtKB=O75594 O75594 PGLYRP1 PTHR11022:SF58 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN RECOGNITION PROTEIN 1 HUMAN|HGNC=21328|UniProtKB=Q8WWR8 Q8WWR8 NEU4 PTHR10628:SF22 SIALIDASE SIALIDASE-4 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carbohydrate metabolic process#GO:0005975;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 hydrolase#PC00121 HUMAN|HGNC=3073|UniProtKB=Q16829 Q16829 DUSP7 PTHR10159:SF305 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 7 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;kinase activity#GO:0016301;phosphoprotein phosphatase activity#GO:0004721;kinase binding#GO:0019900;protein kinase activity#GO:0004672;phosphoric ester hydrolase activity#GO:0042578;MAP kinase activity#GO:0004707;transferase activity#GO:0016740;hydrolase activity#GO:0016787;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of MAP kinase activity#GO:0043407;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=26552|UniProtKB=Q8N5R6 Q8N5R6 CCDC33 PTHR21623:SF2 SPERIOLIN-BINDING FACTOR COILED-COIL DOMAIN-CONTAINING PROTEIN 33 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=2980|UniProtKB=Q9UJW3 Q9UJW3 DNMT3L PTHR23068:SF13 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3-LIKE DNA methyltransferase#PC00013 HUMAN|HGNC=18934|UniProtKB=Q8IUC3 Q8IUC3 KRTAP7-1 PTHR38504:SF1 KERATIN-ASSOCIATED PROTEIN 7-1 KERATIN-ASSOCIATED PROTEIN 7-1 HUMAN|HGNC=6262|UniProtKB=Q9NPI9 Q9NPI9 KCNJ16 PTHR11767:SF24 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 16 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=15865|UniProtKB=Q2M2Z5 Q2M2Z5 KIZ PTHR16299:SF2 CENTROSOMAL PROTEIN KIZUNA CENTROSOMAL PROTEIN KIZUNA HUMAN|HGNC=30774|UniProtKB=Q6VUC0 Q6VUC0 TFAP2E PTHR10812:SF13 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-EPSILON sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 general transcription factor#PC00259 HUMAN|HGNC=1323|UniProtKB=P0C0L4 P0C0L4 C4A PTHR11412:SF86 MACROGLOBULIN / COMPLEMENT COMPLEMENT C4-A-RELATED activation of immune response#GO:0002253;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;response to stimulus#GO:0050896;protein activation cascade#GO:0072376;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;immune effector process#GO:0002252;positive regulation of biological process#GO:0048518;complement activation#GO:0006956;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=20958|UniProtKB=Q9P2C4 Q9P2C4 TMEM181 PTHR31918:SF1 TRANSMEMBRANE PROTEIN 181 TRANSMEMBRANE PROTEIN 181 HUMAN|HGNC=5193|UniProtKB=Q7LGA3 Q7LGA3 HS2ST1 PTHR12129:SF17 HEPARAN SULFATE 2-O-SULFOTRANSFERASE HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;heparan sulfate proteoglycan metabolic process#GO:0030201;proteoglycan biosynthetic process#GO:0030166;cellular carbohydrate metabolic process#GO:0044262;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;cellular polysaccharide biosynthetic process#GO:0033692;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=18508|UniProtKB=Q96RD9 Q96RD9 FCRL5 PTHR11481:SF68 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=29108|UniProtKB=Q68CR1 Q68CR1 SEL1L3 PTHR44444:SF1 PROTEIN SEL-1 HOMOLOG 3 PROTEIN SEL-1 HOMOLOG 3 HUMAN|HGNC=9498|UniProtKB=P07602 P07602 PSAP PTHR11480:SF36 SAPOSIN-RELATED PROSAPOSIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26611|UniProtKB=Q9Y4D8 Q9Y4D8 HECTD4 PTHR46435:SF1 E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED ubiquitin-protein ligase#PC00234 HUMAN|HGNC=11805|UniProtKB=Q13009 Q13009 TIAM1 PTHR46001:SF1 TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG T-LYMPHOMA INVASION AND METASTASIS-INDUCING PROTEIN 1 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of GTPase activity#GO:0043087;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron differentiation#GO:0045664;positive regulation of hydrolase activity#GO:0051345;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;positive regulation of cell projection organization#GO:0031346;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;system development#GO:0048731;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;positive regulation of neuron differentiation#GO:0045666;cellular response to stimulus#GO:0051716;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699 cytoplasm#GO:0005737;synapse#GO:0045202;intracellular#GO:0005622;cell junction#GO:0030054;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Ras Pathway#P04393>Tiam1#P04571 HUMAN|HGNC=23471|UniProtKB=Q6P6B7 Q6P6B7 ANKRD16 PTHR24173:SF72 FAMILY NOT NAMED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16 HUMAN|HGNC=13862|UniProtKB=Q9NY30 Q9NY30 BTG4 PTHR22978:SF5 B-CELL TRANSLOCATION GENE PROTEIN BTG4 negative regulation of biological process#GO:0048519;regulation of cell population proliferation#GO:0042127;negative regulation of cell cycle#GO:0045786;nuclear division#GO:0000280;cell cycle process#GO:0022402;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular process#GO:0009987;cell population proliferation#GO:0008283;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;negative regulation of cell population proliferation#GO:0008285;regulation of mitotic cell cycle#GO:0007346;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=10384|UniProtKB=P62280 P62280 RPS11 PTHR10744:SF9 40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER 40S RIBOSOMAL PROTEIN S11 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=19162|UniProtKB=Q9P2P6 Q9P2P6 STARD9 PTHR47117:SF1 STAR-RELATED LIPID TRANSFER PROTEIN 9 STAR-RELATED LIPID TRANSFER PROTEIN 9 HUMAN|HGNC=4892|UniProtKB=Q93099 Q93099 HGD PTHR11056:SF0 HOMOGENTISATE 1,2-DIOXYGENASE HOMOGENTISATE 1,2-DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;aromatic amino acid family metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxygenase#PC00177 HUMAN|HGNC=16947|UniProtKB=O75477 O75477 ERLIN1 PTHR15351:SF2 ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG ERLIN-1 lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;cholesterol binding#GO:0015485;sterol binding#GO:0032934;steroid binding#GO:0005496 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=34527|UniProtKB=A6H8M9 A6H8M9 CDHR4 PTHR24028:SF123 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 4 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 HUMAN|HGNC=23052|UniProtKB=Q96KC2 Q96KC2 ARL5B PTHR11711:SF146 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5B carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 G-protein#PC00020 HUMAN|HGNC=29099|UniProtKB=Q9Y4R8 Q9Y4R8 TELO2 PTHR15830:SF10 TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;heat shock protein binding#GO:0031072;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;Hsp90 protein binding#GO:0051879 cellular aromatic compound metabolic process#GO:0006725;telomere maintenance via telomere lengthening#GO:0010833;cellular component biogenesis#GO:0044085;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;telomere-telomerase complex assembly#GO:1905324;protein stabilization#GO:0050821;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;telomere maintenance via telomerase#GO:0007004;anatomical structure homeostasis#GO:0060249;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of protein stability#GO:0031647;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;RNA-dependent DNA biosynthetic process#GO:0006278;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;nuclear chromosome, telomeric region#GO:0000784;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular#GO:0005622;chromosome#GO:0005694;TORC2 complex#GO:0031932;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 HUMAN|HGNC=27406|UniProtKB=C9JVW0 C9JVW0 INAFM1 PTHR34929:SF2 ZGC:153157 TRANSMEMBRANE PROTEIN INAFM1-RELATED calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;channel activity#GO:0015267;transporter activity#GO:0005215 HUMAN|HGNC=24180|UniProtKB=Q8IZ73 Q8IZ73 RPUSD2 PTHR21600:SF40 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 2 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA processing factor#PC00147 HUMAN|HGNC=9611|UniProtKB=Q05397 Q05397 PTK2 PTHR24418:SF78 TYROSINE-PROTEIN KINASE FOCAL ADHESION KINASE 1 synapse#GO:0045202;somatodendritic compartment#GO:0036477;anchoring junction#GO:0070161;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 Angiogenesis#P00005>FAK#P00209;CCKR signaling map#P06959>FAK1#P07129;VEGF signaling pathway#P00056>FAK#P01420;Integrin signalling pathway#P00034>FAK#P00932;Gonadotropin-releasing hormone receptor pathway#P06664>FAK#P06707 HUMAN|HGNC=30721|UniProtKB=Q9BXG8 Q9BXG8 SPZ1 PTHR47889:SF1 SPERMATOGENIC LEUCINE ZIPPER PROTEIN 1 SPERMATOGENIC LEUCINE ZIPPER PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=13744|UniProtKB=Q15011 Q15011 HERPUD1 PTHR12943:SF7 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UBIQUITIN-LIKE DOMAIN MEMBER 1 PROTEIN ion channel binding#GO:0044325;protein binding#GO:0005515;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;regulation of protein metabolic process#GO:0051246;divalent inorganic cation homeostasis#GO:0072507;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;regulation of biological quality#GO:0065008;cellular calcium ion homeostasis#GO:0006874;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular cation homeostasis#GO:0030003;response to endoplasmic reticulum stress#GO:0034976;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cell communication#GO:0007154;programmed cell death#GO:0012501;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cation homeostasis#GO:0055080;cellular response to topologically incorrect protein#GO:0035967;cellular ion homeostasis#GO:0006873;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;intrinsic apoptotic signaling pathway#GO:0097193;negative regulation of cell death#GO:0060548;apoptotic signaling pathway#GO:0097190;response to stress#GO:0006950;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;metal ion homeostasis#GO:0055065;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of cellular metabolic process#GO:0031323;cellular metal ion homeostasis#GO:0006875;negative regulation of biological process#GO:0048519;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;cellular homeostasis#GO:0019725;ion homeostasis#GO:0050801;negative regulation of programmed cell death#GO:0043069;response to unfolded protein#GO:0006986;cell death#GO:0008219;catabolic process#GO:0009056;cellular divalent inorganic cation homeostasis#GO:0072503;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;signaling#GO:0023052;regulation of cellular protein catabolic process#GO:1903362;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;regulation of response to stress#GO:0080134;homeostatic process#GO:0042592;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;chemical homeostasis#GO:0048878;negative regulation of apoptotic process#GO:0043066;cellular chemical homeostasis#GO:0055082;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;regulation of cell death#GO:0010941;ubiquitin-dependent ERAD pathway#GO:0030433;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=20568|UniProtKB=Q15629 Q15629 TRAM1 PTHR12371:SF3 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 1 cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=15625|UniProtKB=A2RRP1 A2RRP1 NBAS PTHR15922:SF2 NEUROBLASTOMA-AMPLIFIED SEQUENCE NEUROBLASTOMA-AMPLIFIED SEQUENCE HUMAN|HGNC=7756|UniProtKB=P48681 P48681 NES PTHR47051:SF1 NESTIN NESTIN protein binding#GO:0005515;chemokine receptor binding#GO:0042379;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 protein-containing complex disassembly#GO:0032984;cellular protein complex disassembly#GO:0043624;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cytoskeleton organization#GO:0007010;positive regulation of cytoskeleton organization#GO:0051495;intermediate filament cytoskeleton organization#GO:0045104;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intracellular#GO:0005622;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 HUMAN|HGNC=29212|UniProtKB=Q96KM6 Q96KM6 ZNF512B PTHR22979:SF3 ZINC FINGER PROTEIN-RELATED ZINC FINGER PROTEIN 512B HUMAN|HGNC=24136|UniProtKB=Q8NHY0 Q8NHY0 B4GALNT2 PTHR15046:SF2 GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN BETA-1,4 N-ACETYLGALACTOSAMINYLTRANSFERASE 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;UDP-N-acetylglucosamine metabolic process#GO:0006047;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;amino sugar metabolic process#GO:0006040;nucleobase-containing small molecule metabolic process#GO:0055086;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 HUMAN|HGNC=23382|UniProtKB=Q96J77 Q96J77 TPD52L3 PTHR19307:SF5 TUMOR PROTEIN D52 TUMOR PROTEIN D55 HUMAN|HGNC=19343|UniProtKB=Q8NDV1 Q8NDV1 ST6GALNAC3 PTHR45906:SF2 FAMILY NOT NAMED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 3 transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;carbohydrate metabolic process#GO:0005975;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=13414|UniProtKB=Q9NZK7 Q9NZK7 PLA2G2E PTHR11716:SF56 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP IIE SECRETORY PHOSPHOLIPASE A2 cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;anion binding#GO:0043168;phospholipase activity#GO:0004620;ion binding#GO:0043167;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phospholipase#PC00186 HUMAN|HGNC=30605|UniProtKB=Q9HD40 Q9HD40 SEPSECS PTHR12944:SF2 SOLUBLE LIVER ANTIGEN/LIVER PANCREAS ANTIGEN O-PHOSPHOSERYL-TRNA(SEC) SELENIUM TRANSFERASE tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=31906|UniProtKB=P0CL80 P0CL80 GAGE12F PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=29044|UniProtKB=O75064 O75064 DENND4B PTHR12296:SF18 C-MYC PROMOTER BINDING PROTEIN DENN DOMAIN-CONTAINING PROTEIN 4B Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;regulation of Ras protein signal transduction#GO:0046578;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=4041|UniProtKB=Q9NPG1 Q9NPG1 FZD3 PTHR11309:SF22 FRIZZLED FRIZZLED-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Angiogenesis#P00005>FRP#P00237;Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 HUMAN|HGNC=13258|UniProtKB=Q8WTT0 Q8WTT0 CLEC4C PTHR22802:SF423 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER C membrane traffic protein#PC00150 HUMAN|HGNC=10895|UniProtKB=O75351 O75351 VPS4B PTHR23074:SF72 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4B pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;ATPase activity#GO:0016887 endosomal transport#GO:0016197;cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=19191|UniProtKB=Q8NF50 Q8NF50 DOCK8 PTHR23317:SF74 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 8 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=3954|UniProtKB=Q14331 Q14331 FRG1 PTHR12928:SF3 FRG1 PROTEIN PROTEIN FRG1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;catalytic step 2 spliceosome#GO:0071013;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974 RNA splicing factor#PC00148 HUMAN|HGNC=1745|UniProtKB=O00311 O00311 CDC7 PTHR11909:SF7 CASEIN KINASE-RELATED CELL DIVISION CYCLE 7-RELATED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;peptidyl-serine modification#GO:0018209;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=30935|UniProtKB=Q9H869 Q9H869 YY1AP1 PTHR16088:SF3 YY1 ASSOCIATED PROTEIN-RELATED GON-4-LIKE PROTEIN-RELATED transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=11172|UniProtKB=Q13596 Q13596 SNX1 PTHR10555:SF129 SORTING NEXIN SORTING NEXIN-1 lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=16270|UniProtKB=O95907 O95907 SLC16A8 PTHR11360:SF26 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=21792|UniProtKB=Q8ND71 Q8ND71 GIMAP8 PTHR10903:SF73 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 8 small GTPase#PC00208 HUMAN|HGNC=26845|UniProtKB=Q8N819 Q8N819 PPM1N PTHR47992:SF59 ALPHABET, ISOFORM E-RELATED PROTEIN PHOSPHATASE 1N-RELATED regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;negative regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043124;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11001|UniProtKB=O00337 O00337 SLC28A1 PTHR10590:SF16 SODIUM/NUCLEOSIDE COTRANSPORTER SODIUM/NUCLEOSIDE COTRANSPORTER 1 carbohydrate derivative transmembrane transporter activity#GO:1901505;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;nucleoside transmembrane transporter activity#GO:0005337;transmembrane transporter activity#GO:0022857;nucleobase transmembrane transporter activity#GO:0015205;metal ion transmembrane transporter activity#GO:0046873;nucleobase-containing compound transmembrane transporter activity#GO:0015932;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=10996|UniProtKB=O14975 O14975 SLC27A2 PTHR43107:SF13 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN VERY LONG-CHAIN ACYL-COA SYNTHETASE ligase activity#GO:0016874;transporter activity#GO:0005215;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=26316|UniProtKB=Q96LU7 Q96LU7 MYRFL PTHR13029:SF17 UNCHARACTERIZED MYELIN REGULATORY FACTOR-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;protein processing#GO:0016485;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=13734|UniProtKB=Q6IB77 Q6IB77 GLYAT PTHR15298:SF9 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=26428|UniProtKB=Q6NZ36 Q6NZ36 FAAP20 PTHR37862:SF1 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 20 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 20 HUMAN|HGNC=37279|UniProtKB=B2RXF0 B2RXF0 TMEM229A PTHR31746:SF2 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229A HUMAN|HGNC=717|UniProtKB=P51689 P51689 ARSD PTHR42693:SF12 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE D hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=21336|UniProtKB=Q9NTX7 Q9NTX7 RNF146 PTHR13417:SF2 UNCHARACTERIZED E3 UBIQUITIN-PROTEIN LIGASE RNF146 carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28157|UniProtKB=Q53EU6 Q53EU6 GPAT3 PTHR23063:SF10 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 3 acyltransferase#PC00042 HUMAN|HGNC=30114|UniProtKB=Q8NDB6 Q8NDB6 FAM156A PTHR31577:SF3 DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 3-RELATED PROTEIN FAM156A/FAM156B HUMAN|HGNC=9681|UniProtKB=Q13332 Q13332 PTPRS PTHR19134:SF472 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE S hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=16389|UniProtKB=Q96EW2 Q96EW2 HSPBAP1 PTHR12461:SF43 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HSPB1-ASSOCIATED PROTEIN 1 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 HUMAN|HGNC=13503|UniProtKB=Q9HC78 Q9HC78 ZBTB20 PTHR24399:SF19 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 20 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28074|UniProtKB=Q49B96 Q49B96 COX19 PTHR21107:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=11895|UniProtKB=Q03169 Q03169 TNFAIP2 PTHR21292:SF4 EXOCYST COMPLEX COMPONENT SEC6-RELATED TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;vesicle organization#GO:0016050;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 membrane traffic protein#PC00150 HUMAN|HGNC=3597|UniProtKB=P35544 P35544 FAU PTHR12650:SF32 40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI UBIQUITIN-LIKE PROTEIN FUBI cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=26307|UniProtKB=Q8WVB3 Q8WVB3 HEXD PTHR21040:SF6 UNCHARACTERIZED HEXOSAMINIDASE D HUMAN|HGNC=30613|UniProtKB=Q5MJ70 Q5MJ70 SPDYA PTHR31545:SF4 SEEDY PROTEIN A/C FAMILY MEMBER SPEEDY PROTEIN A HUMAN|HGNC=13056|UniProtKB=O14978 O14978 ZNF263 PTHR23226:SF224 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 263 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=31817|UniProtKB=Q5JNZ5 Q5JNZ5 RPS26P11 PTHR12538:SF7 40S RIBOSOMAL PROTEIN S26 40S RIBOSOMAL PROTEIN S26-RELATED structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=14605|UniProtKB=P58397 P58397 ADAMTS12 PTHR13723:SF189 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 12 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=21307|UniProtKB=Q86SJ6 Q86SJ6 DSG4 PTHR24025:SF10 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-4 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cadherin#PC00057 HUMAN|HGNC=19342|UniProtKB=Q9BVH7 Q9BVH7 ST6GALNAC5 PTHR45906:SF5 FAMILY NOT NAMED ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 5 transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;carbohydrate metabolic process#GO:0005975;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=4182|UniProtKB=P32455 P32455 GBP1 PTHR10751:SF113 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 heterotrimeric G-protein#PC00117 HUMAN|HGNC=12922|UniProtKB=P52744 P52744 ZNF138 PTHR24384:SF211 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 138-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=12894|UniProtKB=Q8NC26 Q8NC26 ZNF114 PTHR24384:SF6 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 114 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=360|UniProtKB=O43918 O43918 AIRE PTHR47025:SF2 AUTOIMMUNE REGULATOR AUTOIMMUNE REGULATOR HUMAN|HGNC=17562|UniProtKB=Q969L4 Q969L4 LSM10 PTHR21196:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 HUMAN|HGNC=17896|UniProtKB=Q9UMS4 Q9UMS4 PRPF19 PTHR43995:SF1 PRE-MRNA-PROCESSING FACTOR 19 PRE-MRNA-PROCESSING FACTOR 19 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Lsm2-8 complex#GO:0120115;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA processing factor#PC00147 mRNA splicing#P00058>U4#P01476 HUMAN|HGNC=23170|UniProtKB=O75717 O75717 WDHD1 PTHR19932:SF10 WD REPEAT AND HMG-BOX DNA BINDING PROTEIN WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;organelle organization#GO:0006996;DNA biosynthetic process#GO:0071897;cell cycle#GO:0007049;organelle fission#GO:0048285;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;pre-replicative complex#GO:0036387;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;MCM complex#GO:0042555;CMG complex#GO:0071162;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pre-replicative complex#GO:0005656;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nuclear replication fork#GO:0043596;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;replication fork#GO:0005657 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=4023|UniProtKB=P51114 P51114 FXR1 PTHR10603:SF6 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;protein homodimerization activity#GO:0042803;organic cyclic compound binding#GO:0097159;binding#GO:0005488;identical protein binding#GO:0042802;protein binding#GO:0005515;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;cellular component biogenesis#GO:0044085;regulation of dendrite development#GO:0050773;regulation of response to DNA damage stimulus#GO:2001020;regulation of protein metabolic process#GO:0051246;heterocycle catabolic process#GO:0046700;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;central nervous system development#GO:0007417;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of translation#GO:0045727;macromolecule catabolic process#GO:0009057;regulation of multicellular organismal process#GO:0051239;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;positive regulation of macromolecule metabolic process#GO:0010604;RNA splicing#GO:0008380;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;multicellular organismal process#GO:0032501;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;plasma membrane bounded cell projection assembly#GO:0120031;translational elongation#GO:0006414;regulation of phosphorylation#GO:0042325;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;alternative mRNA splicing, via spliceosome#GO:0000380;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cell-cell signaling#GO:0007267;mRNA splicing, via spliceosome#GO:0000398;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;heterocycle metabolic process#GO:0046483;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cell morphogenesis#GO:0000902;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;positive regulation of protein metabolic process#GO:0051247;cell morphogenesis involved in neuron differentiation#GO:0048667;aromatic compound catabolic process#GO:0019439;regulation of neurogenesis#GO:0050767;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;cellular macromolecule catabolic process#GO:0044265;negative regulation of gene expression#GO:0010629;cellular localization#GO:0051641;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein modification process#GO:0031399;cell projection organization#GO:0030030;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;dendrite development#GO:0016358;microtubule-based movement#GO:0007018;regulation of synapse organization#GO:0050807;plasma membrane bounded cell projection organization#GO:0120036;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;mRNA metabolic process#GO:0016071;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;synaptic signaling#GO:0099536;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;regulation of dendritic spine development#GO:0060998;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;trans-synaptic signaling#GO:0099537;regulation of RNA stability#GO:0043487;negative regulation of protein metabolic process#GO:0051248;transport along microtubule#GO:0010970;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;neuron projection development#GO:0031175;synapse organization#GO:0050808;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;modulation of chemical synaptic transmission#GO:0050804;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;regulation of trans-synaptic signaling#GO:0099177;neuron projection morphogenesis#GO:0048812;intracellular transport#GO:0046907;regulation of synapse structure or activity#GO:0050803;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of cell morphogenesis involved in differentiation#GO:0010769;regulation of dendrite morphogenesis#GO:0048814;negative regulation of cellular metabolic process#GO:0031324;regulation of phosphate metabolic process#GO:0019220;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;macromolecule modification#GO:0043412;peptide metabolic process#GO:0006518;developmental process#GO:0032502;transport#GO:0006810;RNA processing#GO:0006396;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of cell differentiation#GO:0045595;translation#GO:0006412;positive regulation of response to stimulus#GO:0048584;axo-dendritic transport#GO:0008088;positive regulation of metabolic process#GO:0009893;cytoskeleton-dependent intracellular transport#GO:0030705;RNA catabolic process#GO:0006401;regulation of mRNA processing#GO:0050684;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;regulation of RNA metabolic process#GO:0051252;dendrite morphogenesis#GO:0048813;cell projection assembly#GO:0030031;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of RNA splicing#GO:0043484;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;microtubule-based transport#GO:0099111;regulation of cellular biosynthetic process#GO:0031326;microtubule-based process#GO:0007017;regulation of macromolecule metabolic process#GO:0060255;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell projection assembly#GO:0060491;cell junction organization#GO:0034330;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;establishment of localization in cell#GO:0051649;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 supramolecular complex#GO:0099080;synapse#GO:0045202;postsynaptic density#GO:0014069;intracellular membrane-bounded organelle#GO:0043231;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;distal axon#GO:0150034;plasma membrane region#GO:0098590;postsynapse#GO:0098794;polysome#GO:0005844;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;presynapse#GO:0098793;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;nucleus#GO:0005634;filopodium#GO:0030175;neuronal cell body#GO:0043025;cell junction#GO:0030054;cytoplasmic region#GO:0099568;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasmic ribonucleoprotein granule#GO:0036464;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell body#GO:0044297;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;growth cone#GO:0030426;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 translation factor#PC00223 HUMAN|HGNC=30989|UniProtKB=Q8IY31 Q8IY31 IFT20 PTHR31978:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG HUMAN|Ensembl=ENSG00000275464|UniProtKB=A0A0B4J2E5 A0A0B4J2E5 LOC102724159 PTHR19858:SF0 WD40 REPEAT PROTEIN PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 HUMAN|HGNC=29971|UniProtKB=Q8WVF1 Q8WVF1 OSCP1 PTHR21439:SF0 OXIDORED-NITRO DOMAIN-CONTAINING PROTEIN PROTEIN OSCP1 HUMAN|HGNC=1373|UniProtKB=P00918 P00918 CA2 PTHR18952:SF120 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 2 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=8783|UniProtKB=Q08499 Q08499 PDE4D PTHR11347:SF91 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 HUMAN|HGNC=21350|UniProtKB=O00330 O00330 PDHX PTHR23151:SF9 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED acetyltransferase#PC00038 HUMAN|HGNC=33280|UniProtKB=Q6ZU15 Q6ZU15 SEPTIN14 PTHR18884:SF51 SEPTIN SEPTIN-14 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cell division#GO:0051301;cellular localization#GO:0051641;membrane fission#GO:0090148;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 HUMAN|HGNC=25701|UniProtKB=Q3L8U1 Q3L8U1 CHD9 PTHR46850:SF1 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 HUMAN|HGNC=19689|UniProtKB=Q7Z3Z2 Q7Z3Z2 RD3 PTHR28489:SF1 RENTINAL DEGENERATION 3-LIKE PROTEIN RD3 HUMAN|HGNC=553|UniProtKB=Q06278 Q06278 AOX1 PTHR11908:SF86 XANTHINE DEHYDROGENASE ALDEHYDE OXIDASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidoreductase#PC00176 HUMAN|HGNC=15944|UniProtKB=P09093 P09093 CELA3A PTHR24257:SF11 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 3A serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=6545|UniProtKB=Q8WTW3 Q8WTW3 COG1 PTHR31658:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=24776|UniProtKB=Q3KNS1 Q3KNS1 PTCHD3 PTHR10796:SF60 PATCHED-RELATED PATCHED DOMAIN-CONTAINING PROTEIN 3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 HUMAN|HGNC=17377|UniProtKB=Q8N6M5 Q8N6M5 ALLC PTHR12045:SF3 ALLANTOICASE ALLANTOICASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248 Allantoin degradation#P02725>Allantoate amidohydrolase#P02821 HUMAN|HGNC=6836|UniProtKB=P46821 P46821 MAP1B PTHR13843:SF5 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1B cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;actin binding#GO:0003779;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cellular protein complex disassembly#GO:0043624;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;dendrite development#GO:0016358;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;cell morphogenesis involved in differentiation#GO:0000904;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;protein depolymerization#GO:0051261;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cytosol#GO:0005829;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cell body#GO:0044297;intracellular#GO:0005622;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;microtubule#GO:0005874;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|Gene=YA034_HUMAN|UniProtKB=A8MUI8 A8MUI8 - PTHR11639:SF71 S100 CALCIUM-BINDING PROTEIN UPF0607 PROTEIN ENSP00000332738-RELATED protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=5438|UniProtKB=P01579 P01579 IFNG PTHR11419:SF0 INTERFERON GAMMA INTERFERON GAMMA interferon superfamily#PC00127 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>INFgamma#P00878;Interferon-gamma signaling pathway#P00035>Interferongamma#P00954 HUMAN|HGNC=24353|UniProtKB=P0CG13 P0CG13 CHTF8 PTHR28605:SF3 CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE) CHROMOSOME TRANSMISSION FIDELITY PROTEIN 8 HOMOLOG HUMAN|HGNC=17278|UniProtKB=Q12796 Q12796 PNRC1 PTHR15405:SF4 PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=12775|UniProtKB=O00744 O00744 WNT10B PTHR12027:SF76 WNT RELATED PROTEIN WNT-10B receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=16438|UniProtKB=Q8NBS3 Q8NBS3 SLC4A11 PTHR11453:SF116 ANION EXCHANGE PROTEIN SODIUM BICARBONATE TRANSPORTER-LIKE PROTEIN 11 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;transport#GO:0006810;biological regulation#GO:0065007;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=23587|UniProtKB=A8MYX2 A8MYX2 FAM25E PTHR34994:SF2 PROTEIN FAM25A-RELATED PROTEIN FAM25E HUMAN|HGNC=19620|UniProtKB=A6NND4 A6NND4 OR2AT4 PTHR48001:SF176 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AT4 transmembrane signal receptor#PC00197 HUMAN|HGNC=26188|UniProtKB=Q8N2U9 Q8N2U9 SLC66A2 PTHR14856:SF10 PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN SOLUTE CARRIER FAMILY 66 MEMBER 2 endosomal transport#GO:0016197;cellular localization#GO:0051641;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=29174|UniProtKB=Q2M389 Q2M389 WASHC4 PTHR31409:SF0 WASH COMPLEX SUBUNIT 4 WASH COMPLEX SUBUNIT 4 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;intracellular transport#GO:0046907;cellular component organization#GO:0016043;cellular process#GO:0009987 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=8968|UniProtKB=P01833 P01833 PIGR PTHR11860:SF82 POLYMERIC-IMMUNOGLOBULIN RECEPTOR POLYMERIC IMMUNOGLOBULIN RECEPTOR immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=18331|UniProtKB=Q6NT04 Q6NT04 TIGD7 PTHR19303:SF17 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 7 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 HUMAN|HGNC=37441|UniProtKB=A6NEY3 A6NEY3 GOLGA6L3 PTHR23143:SF19 TRICHOHYALIN-RELATED GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 10-RELATED actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=23527|UniProtKB=Q8TC84 Q8TC84 FANK1 PTHR24183:SF1 FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1 FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;cellular nitrogen compound biosynthetic process#GO:0044271;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;regulation of DNA-binding transcription factor activity#GO:0051090;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;programmed cell death#GO:0012501;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of cell death#GO:0010941;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=9308|UniProtKB=Q15257 Q15257 PTPA PTHR10012:SF0 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B SERINE/THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;isomerase activity#GO:0016853;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;spindle organization#GO:0007051 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphatase activator#PC00182 HUMAN|HGNC=21020|UniProtKB=Q9H0R6 Q9H0R6 QRSL1 PTHR11895:SF153 TRANSAMIDASE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;mitochondrial translation#GO:0032543;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 HUMAN|HGNC=19622|UniProtKB=Q8NG78 Q8NG78 OR8G5 PTHR48018:SF48 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8G5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=18179|UniProtKB=Q96AX1 Q96AX1 VPS33A PTHR11679:SF85 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=16147|UniProtKB=Q9UJA3 Q9UJA3 MCM8 PTHR11630:SF47 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA HELICASE MCM8 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=9037|UniProtKB=Q9UP65 Q9UP65 PLA2G4C PTHR10728:SF39 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 GAMMA hydrolase activity, acting on ester bonds#GO:0016788;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;phospholipid binding#GO:0005543;carboxylic ester hydrolase activity#GO:0052689;cation binding#GO:0043169;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;hydrolase activity#GO:0016787;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;plasma membrane#GO:0005886 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Angiogenesis#P00005>cPLA2#P00251 HUMAN|HGNC=25104|UniProtKB=Q2VPB7 Q2VPB7 AP5B1 PTHR34033:SF1 AP-5 COMPLEX SUBUNIT BETA-1 AP-5 COMPLEX SUBUNIT BETA-1 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cellular anatomical entity#GO:0110165;membrane#GO:0016020;AP-type membrane coat adaptor complex#GO:0030119 HUMAN|HGNC=14825|UniProtKB=Q8NH21 Q8NH21 OR4F5 PTHR48002:SF51 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4F17-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=6565|UniProtKB=P56470 P56470 LGALS4 PTHR11346:SF32 GALECTIN GALECTIN-4 extracellular matrix protein#PC00102 HUMAN|HGNC=15261|UniProtKB=Q8N127 Q8N127 OR5AS1 PTHR26452:SF704 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AS1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=5908|UniProtKB=P01717 P01717 IGLV3-25 PTHR23267:SF465 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-25 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=31406|UniProtKB=Q9Y2I8 Q9Y2I8 WDR37 PTHR19855:SF12 WD40 REPEAT PROTEIN 12, 37 WD REPEAT-CONTAINING PROTEIN 37 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991 HUMAN|HGNC=18510|UniProtKB=Q5T6X5 Q5T6X5 GPRC6A PTHR24061:SF5 CALCIUM-SENSING RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 6 MEMBER A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=25047|UniProtKB=Q96FV0 Q96FV0 LRRC46 PTHR45973:SF1 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 46 phosphatase modulator#PC00184 HUMAN|HGNC=1965|UniProtKB=Q07001 Q07001 CHRND PTHR18945:SF61 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT DELTA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>delta#P01092 HUMAN|HGNC=20945|UniProtKB=Q8IUK5 Q8IUK5 PLXDC1 PTHR13055:SF10 TUMOR ENDOTHELIAL MARKER 7 RELATED PLEXIN DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=13585|UniProtKB=Q9NRD1 Q9NRD1 FBXO6 PTHR12125:SF12 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 6 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 HUMAN|HGNC=18800|UniProtKB=Q9P215 Q9P215 POGK PTHR19303:SF21 TRANSPOSON POGO TRANSPOSABLE ELEMENT WITH KRAB DOMAIN nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 HUMAN|HGNC=847|UniProtKB=P18859 P18859 ATP5PF PTHR12441:SF10 ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL ATP SYNTHASE-COUPLING FACTOR 6, MITOCHONDRIAL envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 HUMAN|HGNC=10664|UniProtKB=Q6UX04 Q6UX04 CWC27 PTHR45625:SF6 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 chaperone#PC00072 HUMAN|HGNC=6152|UniProtKB=P20702 P20702 ITGAX PTHR23220:SF131 INTEGRIN ALPHA INTEGRIN ALPHA-X integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=6193|UniProtKB=P52333 P52333 JAK3 PTHR45807:SF3 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK3 PDGF signaling pathway#P00047>Jak#P01155;Interleukin signaling pathway#P00036>Jak#P00978;JAK/STAT signaling pathway#P00038>Jak#P01034 HUMAN|HGNC=1580|UniProtKB=O95067 O95067 CCNB2 PTHR10177:SF184 CYCLINS G2/MITOTIC-SPECIFIC CYCLIN-B2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 HUMAN|HGNC=8227|UniProtKB=Q8NH92 Q8NH92 OR1S1 PTHR48001:SF115 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1S1-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=30777|UniProtKB=Q96GN5 Q96GN5 CDCA7L PTHR31169:SF4 OS05G0300700 PROTEIN CELL DIVISION CYCLE-ASSOCIATED 7-LIKE PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=17689|UniProtKB=Q969H6 Q969H6 POP5 PTHR10993:SF12 OCTANOYLTRANSFERASE RIBONUCLEASE P/MRP PROTEIN SUBUNIT POP5 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on a tRNA#GO:0140101 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;tRNA processing#GO:0008033;RNA processing#GO:0006396;protein modification process#GO:0036211;gene expression#GO:0010467;peptidyl-amino acid modification#GO:0018193;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;peptidyl-lysine modification#GO:0018205;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein maturation#GO:0051604;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613 small nucleolar ribonucleoprotein complex#GO:0005732;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172;catalytic complex#GO:1902494 transferase#PC00220 HUMAN|HGNC=9719|UniProtKB=P50542 P50542 PEX5 PTHR10130:SF2 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein targeting to peroxisome#GO:0006625;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein localization to peroxisome#GO:0072662;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;microbody membrane#GO:0031903;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=17485|UniProtKB=Q969Q6 Q969Q6 PPP2R3C PTHR12085:SF3 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;centrosome#GO:0005813 protein phosphatase#PC00195 HUMAN|HGNC=2446|UniProtKB=P07498 P07498 CSN3 PTHR11470:SF2 KAPPA CASEIN KAPPA-CASEIN gland development#GO:0048732;animal organ development#GO:0048513;multicellular organism development#GO:0007275;transport#GO:0006810;developmental process#GO:0032502;regulation of protein stability#GO:0031647;regulation of body fluid levels#GO:0050878;protein stabilization#GO:0050821;localization#GO:0051179;system development#GO:0048731;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;secretion#GO:0046903;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;mammary gland development#GO:0030879 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 storage protein#PC00210 HUMAN|HGNC=30064|UniProtKB=Q86U86 Q86U86 PBRM1 PTHR16062:SF19 SWI/SNF-RELATED PROTEIN POLYBROMO-1 protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=20233|UniProtKB=Q9Y2Z9 Q9Y2Z9 COQ6 PTHR43876:SF7 UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ubiquinone biosynthetic process#GO:0006744;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 oxygenase#PC00177 HUMAN|HGNC=25191|UniProtKB=Q8NFR7 Q8NFR7 CCDC148 PTHR21549:SF1 MUTATED IN BLADDER CANCER 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 148 HUMAN|HGNC=30570|UniProtKB=Q7L945 Q7L945 ZNF627 PTHR24379:SF78 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 627 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4823|UniProtKB=P69905 P69905 HBA2 PTHR11442:SF48 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ALPHA small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;intracellular#GO:0005622;extracellular region#GO:0005576 HUMAN|HGNC=20249|UniProtKB=Q7Z699 Q7Z699 SPRED1 PTHR11202:SF18 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of response to DNA damage stimulus#GO:2001020;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;negative regulation of MAPK cascade#GO:0043409;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of vasculature development#GO:1901342;regulation of molecular function#GO:0065009;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;vasculature development#GO:0001944;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;tube development#GO:0035295;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;cellular response to DNA damage stimulus#GO:0006974;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;angiogenesis#GO:0001525;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;protein deacetylation#GO:0006476;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;MAPK cascade#GO:0000165;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of angiogenesis#GO:0045765;positive regulation of response to DNA damage stimulus#GO:2001022;signal transduction by p53 class mediator#GO:0072331;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;negative regulation of multicellular organismal process#GO:0051241;signal transduction in response to DNA damage#GO:0042770;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;metabolic process#GO:0008152;negative regulation of MAP kinase activity#GO:0043407;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;protein deacylation#GO:0035601;negative regulation of cellular protein metabolic process#GO:0032269;peptidyl-threonine phosphorylation#GO:0018107;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18532|UniProtKB=Q8NHZ7 Q8NHZ7 MBD3L2 PTHR12396:SF6 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 3-LIKE 2-RELATED HUMAN|HGNC=20889|UniProtKB=O94898 O94898 LRIG2 PTHR24373:SF306 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS PROTEIN 2 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=21373|UniProtKB=Q8N2I9 Q8N2I9 STK40 PTHR22961:SF16 SER/THR PROTEIN KINASE-TRB SERINE/THREONINE-PROTEIN KINASE 40 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=30229|UniProtKB=P27469 P27469 G0S2 PTHR15570:SF2 G0/G1 SWITCH PROTEIN 2 G0/G1 SWITCH PROTEIN 2 HUMAN|HGNC=43771|UniProtKB=P0DJG4 P0DJG4 THEGL PTHR15901:SF15 TESTICULAR HAPLOID EXPRESSED GENE PROTEIN TESTICULAR HAPLOID EXPRESSED GENE PROTEIN-LIKE HUMAN|HGNC=28984|UniProtKB=Q12768 Q12768 WASHC5 PTHR15691:SF6 WASH COMPLEX SUBUNIT 5 WASH COMPLEX SUBUNIT 5 membrane traffic protein#PC00150 HUMAN|HGNC=1635|UniProtKB=P29016 P29016 CD1B PTHR16675:SF130 MHC CLASS I-RELATED T-CELL SURFACE GLYCOPROTEIN CD1B lipid binding#GO:0008289;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 immune response#GO:0006955;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;T cell mediated immunity#GO:0002456;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=51259|UniProtKB=H7C241 H7C241 CLDN34 PTHR12002:SF4 CLAUDIN CLAUDIN-34 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=3488|UniProtKB=P14921 P14921 ETS1 PTHR11849:SF209 ETS PROTEIN C-ETS-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167;Ras Pathway#P04393>Ets#P04563;VEGF signaling pathway#P00056>Ets#P01419;Angiogenesis#P00005>Ets#P00188 HUMAN|HGNC=23801|UniProtKB=O60292 O60292 SIPA1L3 PTHR15711:SF15 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 3 GTPase-activating protein#PC00257 HUMAN|HGNC=6008|UniProtKB=P01589 P01589 IL2RA PTHR10573:SF0 INTERLEUKIN-2 RECEPTOR ALPHA CHAIN INTERLEUKIN-2 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;growth factor binding#GO:0019838;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to stress#GO:0006950;defense response#GO:0006952;inflammatory response#GO:0006954 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=10024|UniProtKB=P12271 P12271 RLBP1 PTHR10174:SF200 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED RETINALDEHYDE-BINDING PROTEIN 1 phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 HUMAN|HGNC=26967|UniProtKB=Q8IXR9 Q8IXR9 C12orf56 PTHR35354:SF1 RGD1561648 RGD1561648 HUMAN|HGNC=25172|UniProtKB=P0C091 P0C091 FREM3 PTHR45739:SF5 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 3 HUMAN|HGNC=11630|UniProtKB=P35680 P35680 HNF1B PTHR11568:SF2 HEPATOCYTE NUCLEAR FACTOR 1 HEPATOCYTE NUCLEAR FACTOR 1-BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=13487|UniProtKB=Q96QK1 Q96QK1 VPS35 PTHR11099:SF0 VACUOLAR SORTING PROTEIN 35 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=12007|UniProtKB=O43399 O43399 TPD52L2 PTHR19307:SF13 TUMOR PROTEIN D52 TUMOR PROTEIN D54 HUMAN|HGNC=15893|UniProtKB=Q9NUR3 Q9NUR3 TMEM74B PTHR16125:SF4 TRANSMEMBRANE PROTEIN 74 TRANSMEMBRANE PROTEIN 74B HUMAN|HGNC=34404|UniProtKB=Q1ED39 Q1ED39 KNOP1 PTHR22426:SF4 UNCHARACTERIZED LYSINE-RICH NUCLEOLAR PROTEIN 1 HUMAN|HGNC=21293|UniProtKB=Q8NDA2 Q8NDA2 HMCN2 PTHR24373:SF353 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN HEMICENTIN-2 transmembrane signal receptor#PC00197 HUMAN|HGNC=23188|UniProtKB=Q7Z6K1 Q7Z6K1 THAP5 PTHR46927:SF1 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 5 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=29465|UniProtKB=Q5T752 Q5T752 LCE1D PTHR23263:SF102 SMALL PROLINE-RICH PROTEIN LATE CORNIFIED ENVELOPE PROTEIN 1D HUMAN|HGNC=17113|UniProtKB=Q9NWT6 Q9NWT6 HIF1AN PTHR12461:SF93 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 HUMAN|HGNC=26015|UniProtKB=Q59GN2 Q59GN2 RPL39P5 PTHR19970:SF36 RIBOSOMAL PROTEIN L39E 60S RIBOSOMAL PROTEIN L39-LIKE 5-RELATED cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=5361|UniProtKB=Q02363 Q02363 ID2 PTHR11723:SF5 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-2 molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>Id2#P06804 HUMAN|HGNC=14333|UniProtKB=Q8WXS3 Q8WXS3 BAALC PTHR14731:SF0 BRAIN AND ACUTE LEUKEMIA CYTOPLASMIC PROTEIN BRAIN AND ACUTE LEUKEMIA CYTOPLASMIC PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9548|UniProtKB=P35998 P35998 PSMC2 PTHR23073:SF13 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 7 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;TBP-class protein binding#GO:0017025 positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription, initiation#GO:2000142;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of transcription initiation from RNA polymerase II promoter#GO:0060260;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;positive regulation of transcription initiation from RNA polymerase II promoter#GO:0060261;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of protein-containing complex assembly#GO:0043254;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of RNA polymerase II transcription preinitiation complex assembly#GO:0045899;positive regulation of cellular component biogenesis#GO:0044089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of protein-containing complex assembly#GO:0031334;regulation of primary metabolic process#GO:0080090;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of DNA-templated transcription, initiation#GO:2000144;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;intracellular#GO:0005622;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;proteasome regulatory particle, base subcomplex#GO:0008540 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 HUMAN|HGNC=11477|UniProtKB=Q15528 Q15528 MED22 PTHR12434:SF6 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=30858|UniProtKB=Q15029 Q15029 EFTUD2 PTHR42908:SF6 TRANSLATION ELONGATION FACTOR-RELATED 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;snRNA binding#GO:0017069;nucleoside-triphosphatase activity#GO:0017111 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytosol#GO:0005829;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Lsm2-8 complex#GO:0120115;intracellular#GO:0005622;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 translation elongation factor#PC00222 HUMAN|HGNC=10377|UniProtKB=P05387 P05387 RPLP2 PTHR21141:SF5 60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER 60S ACIDIC RIBOSOMAL PROTEIN P2 ribosomal protein#PC00202 HUMAN|HGNC=20157|UniProtKB=Q9ULT8 Q9ULT8 HECTD1 PTHR45670:SF2 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE HECTD1 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;anatomical structure development#GO:0048856;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein K63-linked ubiquitination#GO:0070534;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=20079|UniProtKB=Q70EL3 Q70EL3 USP50 PTHR21646:SF11 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 50 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=30500|UniProtKB=Q7Z6L0 Q7Z6L0 PRRT2 PTHR14948:SF20 NG5 PROLINE-RICH TRANSMEMBRANE PROTEIN 2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=5619|UniProtKB=A0A0C4DH42 A0A0C4DH42 IGHV3-66 PTHR23266:SF204 IMMUNOGLOBULIN HEAVY CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=28500|UniProtKB=Q8WW14 Q8WW14 C10orf82 PTHR47301:SF1 HYPOTHETICAL PROTEIN LOC681006 HYPOTHETICAL PROTEIN LOC681006 HUMAN|HGNC=863|UniProtKB=O15342 O15342 ATP6V0E1 PTHR12263:SF5 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT E 1 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 ATP synthase#PC00002 HUMAN|HGNC=14515|UniProtKB=Q9NVS2 Q9NVS2 MRPS18A PTHR13479:SF40 30S RIBOSOMAL PROTEIN S18 39S RIBOSOMAL PROTEIN S18A, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribosomal protein#PC00202 HUMAN|HGNC=14550|UniProtKB=Q96JP9 Q96JP9 CDHR1 PTHR24028:SF263 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 1 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=11761|UniProtKB=P48307 P48307 TFPI2 PTHR10083:SF352 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED TISSUE FACTOR PATHWAY INHIBITOR 2 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=13602|UniProtKB=Q9UKA1 Q9UKA1 FBXL5 PTHR13318:SF19 UNCHARACTERIZED F-BOX/LRR-REPEAT PROTEIN 5 inorganic ion homeostasis#GO:0098771;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;iron ion homeostasis#GO:0055072;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;transition metal ion homeostasis#GO:0055076;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=8799|UniProtKB=P04085 P04085 PDGFA PTHR11633:SF3 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR SUBUNIT A growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component movement#GO:0051272;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;inositol lipid-mediated signaling#GO:0048017;positive regulation of ERK1 and ERK2 cascade#GO:0070374;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;regulation of protein serine/threonine kinase activity#GO:0071900;protein autophosphorylation#GO:0046777;phosphatidylinositol-mediated signaling#GO:0048015;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;ERK1 and ERK2 cascade#GO:0070371;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of cell migration#GO:0030335;phosphatidylinositol 3-kinase signaling#GO:0014065;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of phosphatidylinositol 3-kinase signaling#GO:0014066;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477;regulation of transferase activity#GO:0051338 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 PDGF signaling pathway#P00047>PDGF#P01170;Angiogenesis#P00005>PDGF#P00224 HUMAN|HGNC=12579|UniProtKB=O00526 O00526 UPK2 PTHR17573:SF0 UROPLAKIN II UROPLAKIN-2 HUMAN|HGNC=51253|UniProtKB=A0A087WXM9 A0A087WXM9 MEIKIN PTHR38006:SF1 MEIOSIS-SPECIFIC KINETOCHORE PROTEIN MEIOSIS-SPECIFIC KINETOCHORE PROTEIN male gamete generation#GO:0048232;homologous chromosome segregation#GO:0045143;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;meiotic sister chromatid segregation#GO:0045144;chromosome segregation#GO:0007059;M phase#GO:0000279;sister chromatid cohesion#GO:0007062;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle phase#GO:0022403;male meiotic nuclear division#GO:0007140;multi-organism reproductive process#GO:0044703;meiosis I#GO:0007127;multicellular organismal reproductive process#GO:0048609;nuclear chromosome segregation#GO:0098813;meiosis I cell cycle phase#GO:0098764;gamete generation#GO:0007276;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;multicellular organism reproduction#GO:0032504;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;multi-organism process#GO:0051704;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;sexual reproduction#GO:0019953;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;organelle fission#GO:0048285;biological phase#GO:0044848 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome kinetochore#GO:0000777;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 HUMAN|HGNC=3154|UniProtKB=O94769 O94769 ECM2 PTHR46544:SF1 EXTRACELLULAR MATRIX PROTEIN 2-RELATED EXTRACELLULAR MATRIX PROTEIN 2 carbohydrate derivative binding#GO:0097367;binding#GO:0005488;heparin binding#GO:0008201;collagen binding#GO:0005518;protein-containing complex binding#GO:0044877;ion binding#GO:0043167;anion binding#GO:0043168;glycosaminoglycan binding#GO:0005539 positive regulation of cell-substrate adhesion#GO:0010811;biological adhesion#GO:0022610;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;extracellular matrix organization#GO:0030198;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cell adhesion#GO:0045785;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=19742|UniProtKB=Q96L50 Q96L50 LRR1 PTHR45752:SF153 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|HGNC=23249|UniProtKB=Q86VF5 Q86VF5 MOGAT3 PTHR12317:SF36 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 3 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=22968|UniProtKB=P60369 P60369 KRTAP10-3 PTHR23262:SF175 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-1-RELATED HUMAN|HGNC=28053|UniProtKB=Q9UJL9 Q9UJL9 ZFP69B PTHR24381:SF135 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 69 HOMOLOG B DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13016|UniProtKB=Q9UK11 Q9UK11 ZNF223 PTHR24377:SF612 IP01015P-RELATED ZINC FINGER PROTEIN 222-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28944|UniProtKB=A0A087WVF3 A0A087WVF3 TBC1D3D PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=12991|UniProtKB=Q9BSG1 Q9BSG1 ZNF2 PTHR24377:SF885 IP01015P-RELATED ZINC FINGER PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2469|UniProtKB=P21291 P21291 CSRP1 PTHR24215:SF23 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488 sarcomere organization#GO:0045214;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=4540|UniProtKB=P49682 P49682 CXCR3 PTHR10489:SF671 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 3 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=30700|UniProtKB=Q63HK5 Q63HK5 TSHZ3 PTHR12487:SF5 TEASHIRT-RELATED TEASHIRT HOMOLOG 3 binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=23677|UniProtKB=Q5SZB4 Q5SZB4 C9orf50 PTHR36865:SF1 RIKEN CDNA 1700001O22 GENE RIKEN CDNA 1700001O22 GENE HUMAN|HGNC=20186|UniProtKB=Q9H7Z3 Q9H7Z3 NRDE2 PTHR13471:SF0 TETRATRICOPEPTIDE-LIKE HELICAL NUCLEAR EXOSOME REGULATOR NRDE2 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=16924|UniProtKB=Q8WZ64 Q8WZ64 ARAP2 PTHR45899:SF1 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 GTPase-activating protein#PC00257 HUMAN|HGNC=18242|UniProtKB=Q8NEU8 Q8NEU8 APPL2 PTHR46415:SF1 ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2 DCC-INTERACTING PROTEIN 13-BETA bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15184|UniProtKB=Q8NGF9 Q8NGF9 OR4X2 PTHR48002:SF146 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4X2 transmembrane signal receptor#PC00197 HUMAN|HGNC=20267|UniProtKB=Q92623 Q92623 TTC9 PTHR43811:SF2 FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA TETRATRICOPEPTIDE REPEAT PROTEIN 9A chaperone#PC00072 HUMAN|HGNC=28277|UniProtKB=Q8N8B7 Q8N8B7 TCEANC PTHR11477:SF7 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A N-TERMINAL AND CENTRAL DOMAIN-CONTAINING PROTEIN general transcription factor#PC00259 HUMAN|HGNC=3436|UniProtKB=Q92889 Q92889 ERCC4 PTHR10150:SF0 DNA REPAIR ENDONUCLEASE XPF DNA REPAIR ENDONUCLEASE XPF hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;endonuclease activity#GO:0004519;damaged DNA binding#GO:0003684;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;endodeoxyribonuclease activity#GO:0004520;deoxyribonuclease activity#GO:0004536 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;meiotic chromosome separation#GO:0051307;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;nucleotide-excision repair, DNA incision#GO:0033683;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;nucleotide-excision repair complex#GO:0000109;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 endodeoxyribonuclease#PC00093 HUMAN|HGNC=3353|UniProtKB=P09104 P09104 ENO2 PTHR11902:SF10 ENOLASE GAMMA-ENOLASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ATP generation from ADP#GO:0006757;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organelle fusion#GO:0048284;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;ADP metabolic process#GO:0046031;regulation of organelle organization#GO:0033043;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;vacuole fusion, non-autophagic#GO:0042144;regulation of cellular process#GO:0050794;glycolytic process#GO:0006096;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular#GO:0005622 lyase#PC00144 Glycolysis#P00024>Enolase#P00678 HUMAN|HGNC=30240|UniProtKB=Q8WVK2 Q8WVK2 SNRNP27 PTHR31077:SF6 U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=17637|UniProtKB=Q96FX8 Q96FX8 PERP PTHR14399:SF4 P53-INDUCED PROTEIN RELATED P53 APOPTOSIS EFFECTOR RELATED TO PMP-22 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 p53 pathway#P00059>PERP#G01565 HUMAN|HGNC=2044|UniProtKB=Q8N7P3 Q8N7P3 CLDN22 PTHR12002:SF196 CLAUDIN CLAUDIN-22 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=24356|UniProtKB=Q9P126 Q9P126 CLEC1B PTHR46490:SF2 C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 1 MEMBER B HUMAN|HGNC=11174|UniProtKB=O60493 O60493 SNX3 PTHR45963:SF1 RE52028P SORTING NEXIN-3 phosphatidylinositol-3-phosphate binding#GO:0032266;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;establishment of protein localization#GO:0045184;amide transport#GO:0042886;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of protein transport#GO:0051223;regulation of protein localization#GO:0032880;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;cytosolic transport#GO:0016482;protein localization#GO:0008104;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=27607|UniProtKB=O75864 O75864 PPP1R37 PTHR24112:SF61 LEUCINE-RICH REPEAT, ISOFORM F-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 37 HUMAN|HGNC=24510|UniProtKB=Q4KMP7 Q4KMP7 TBC1D10B PTHR22957:SF207 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 10B GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=3030|UniProtKB=P55039 P55039 DRG2 PTHR43127:SF2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=19341|UniProtKB=Q8IU85 Q8IU85 CAMK1D PTHR24347:SF252 SERINE/THREONINE-PROTEIN KINASE CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=11399|UniProtKB=P51957 P51957 NEK4 PTHR24361:SF690 MITOGEN-ACTIVATED KINASE KINASE KINASE SERINE/THREONINE-PROTEIN KINASE NEK4 HUMAN|HGNC=8818|UniProtKB=O43511 O43511 SLC26A4 PTHR11814:SF33 SULFATE TRANSPORTER PENDRIN inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;inorganic anion transmembrane transporter activity#GO:0015103;active ion transmembrane transporter activity#GO:0022853 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=17893|UniProtKB=Q9UHJ9 Q9UHJ9 PGAP2 PTHR12892:SF11 FGF RECEPTOR ACTIVATING PROTEIN 1 POST-GPI ATTACHMENT TO PROTEINS FACTOR 2 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein lipidation#GO:0006497;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 protein modifying enzyme#PC00260 HUMAN|HGNC=9223|UniProtKB=Q06416 Q06416 POU5F1B PTHR11636:SF130 POU DOMAIN POU DOMAIN, CLASS 5, TRANSCRIPTION FACTOR 1B-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=12229|UniProtKB=A0A1B0GX49 A0A1B0GX49 TRBV6-4 PTHR23268:SF19 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 6-2-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=21300|UniProtKB=Q9H633 Q9H633 RPP21 PTHR14742:SF0 RIBONUCLEASE P SUBUNIT P21 RIBONUCLEASE P PROTEIN SUBUNIT P21 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on a tRNA#GO:0140101 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;ribonuclease P complex#GO:0030677;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=25717|UniProtKB=Q9H857 Q9H857 NT5DC2 PTHR12103:SF14 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173 HUMAN|HGNC=29825|UniProtKB=Q9BUA6 Q9BUA6 MYL10 PTHR23049:SF36 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 10 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=24007|UniProtKB=Q5T9A4 Q5T9A4 ATAD3B PTHR23075:SF2 PUTATIVE ATP-ASE ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3B cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7212|UniProtKB=Q96Q89 Q96Q89 KIF20B PTHR24115:SF534 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF20B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=5746|UniProtKB=P01611 P01611 IGKV1D-12 PTHR23267:SF474 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-12-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=18992|UniProtKB=Q8IZF6 Q8IZF6 ADGRG4 PTHR12011:SF277 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=23156|UniProtKB=P26368 P26368 U2AF2 PTHR23139:SF9 RNA-BINDING PROTEIN SPLICING FACTOR U2AF 65 KDA SUBUNIT nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;U1 snRNP#GO:0005685;intracellular organelle lumen#GO:0070013;U2-type spliceosomal complex#GO:0005684;nuclear speck#GO:0016607;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=30879|UniProtKB=Q969R8 Q969R8 ITFG2 PTHR16317:SF1 INTEGRIN ALPHA REPEAT DOMAIN-CONTAINING KICSTOR COMPLEX PROTEIN ITFG2 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052;TOR signaling#GO:0031929 protein-containing complex#GO:0032991 integrin#PC00126 HUMAN|HGNC=3688|UniProtKB=P11362 P11362 FGFR1 PTHR24416:SF131 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;fibroblast growth factor binding#GO:0017134;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of cell differentiation#GO:0045597;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636;Angiogenesis#P00005>FGFR-1#P00186 HUMAN|HGNC=12223|UniProtKB=A0A599 A0A599 TRBV5-6 PTHR23268:SF6 T-CELL RECEPTOR BETA CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=10538|UniProtKB=O43290 O43290 SART1 PTHR14152:SF5 SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES U4/U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA cis splicing, via spliceosome#GO:0045292;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;ribosome biogenesis#GO:0042254;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 extracellular matrix protein#PC00102 HUMAN|HGNC=8939|UniProtKB=Q9UMS5 Q9UMS5 PHTF1 PTHR12680:SF8 PUTATIVE HOMEODOMAIN TRANSCRIPTION FACTOR PHTF HOMEODOMAIN TRANSCRIPTION FACTOR 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=18875|UniProtKB=P59537 P59537 TAS2R43 PTHR11394:SF127 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 43 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=17364|UniProtKB=Q9UBU7 Q9UBU7 DBF4 PTHR15375:SF22 ACTIVATOR OF S-PHASE KINASE-RELATED PROTEIN DBF4 HOMOLOG A protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 cellular aromatic compound metabolic process#GO:0006725;positive regulation of DNA replication#GO:0045740;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of cell cycle process#GO:0090068;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear DNA replication#GO:0033260;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;regulation of cell cycle#GO:0051726;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase activator#PC00138 HUMAN|HGNC=28388|UniProtKB=Q8TC29 Q8TC29 ENKUR PTHR21490:SF0 UNCHARACTERIZED ENKURIN protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 HUMAN|HGNC=19410|UniProtKB=Q86VH5 Q86VH5 LRRTM3 PTHR24373:SF296 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 3 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=11330|UniProtKB=P30872 P30872 SSTR1 PTHR24229:SF38 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 1 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;response to lipid#GO:0033993;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to lipid#GO:0071396;response to estradiol#GO:0032355;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=10853|UniProtKB=O15266 O15266 SHOX PTHR46255:SF2 SHORT STATURE HOMEOBOX SHORT STATURE HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=16743|UniProtKB=Q6S5L8 Q6S5L8 SHC4 PTHR10337:SF12 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 4 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17169|UniProtKB=Q13162 Q13162 PRDX4 PTHR10681:SF128 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-4 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;catabolic process#GO:0009056;cellular response to stress#GO:0033554;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 peroxidase#PC00180 HUMAN|HGNC=28280|UniProtKB=Q6ZRR5 Q6ZRR5 TLCD5 PTHR31898:SF1 TRANSMEMBRANE PROTEIN 136 TLC DOMAIN-CONTAINING PROTEIN 5 HUMAN|HGNC=17981|UniProtKB=O00442 O00442 RTCA PTHR11096:SF0 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;cyclase activity#GO:0009975;catalytic activity#GO:0003824 RNA metabolism protein#PC00031 HUMAN|HGNC=7527|UniProtKB=Q9UIF7 Q9UIF7 MUTYH PTHR42944:SF1 ADENINE DNA GLYCOSYLASE ADENINE DNA GLYCOSYLASE mismatched DNA binding#GO:0030983;nucleic acid binding#GO:0003676;DNA N-glycosylase activity#GO:0019104;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;damaged DNA binding#GO:0003684;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;base-excision repair#GO:0006284;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 DNA glycosylase#PC00010 HUMAN|HGNC=14298|UniProtKB=Q9UBY5 Q9UBY5 LPAR3 PTHR22750:SF21 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=20999|UniProtKB=Q9NPJ3 Q9NPJ3 ACOT13 PTHR21660:SF1 THIOESTERASE SUPERFAMILY MEMBER-RELATED ACYL-COENZYME A THIOESTERASE 13 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 esterase#PC00097 HUMAN|HGNC=12980|UniProtKB=O75820 O75820 ZNF189 PTHR24377:SF316 IP01015P-RELATED ZINC FINGER PROTEIN 189 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25049|UniProtKB=Q6NXE6 Q6NXE6 ARMC6 PTHR22895:SF0 UNCHARACTERIZED ARMADILLO REPEAT-CONTAINING PROTEIN 6 HUMAN|HGNC=26597|UniProtKB=Q6PF15 Q6PF15 KLHL35 PTHR24412:SF187 KELCH PROTEIN KELCH-LIKE PROTEIN 35 scaffold/adaptor protein#PC00226 HUMAN|HGNC=24197|UniProtKB=Q96S95 Q96S95 CAMK2N2 PTHR31007:SF1 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2 protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;protein phosphorylation#GO:0006468;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 kinase inhibitor#PC00139 HUMAN|HGNC=4133|UniProtKB=O43603 O43603 GALR2 PTHR24230:SF13 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 2 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=30123|UniProtKB=Q6PL18 Q6PL18 ATAD2 PTHR23069:SF4 AAA DOMAIN-CONTAINING ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2 pyrophosphatase activity#GO:0016462;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;histone binding#GO:0042393;ATPase activity#GO:0016887 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of chromatin silencing#GO:0031935;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of chromatin silencing#GO:0031936;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of chromatin organization#GO:1902275;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=584|UniProtKB=P02743 P02743 APCS PTHR45869:SF5 C-REACTIVE PROTEIN-RELATED SERUM AMYLOID P-COMPONENT complement binding#GO:0001848;low-density lipoprotein particle binding#GO:0030169;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488 response to external biotic stimulus#GO:0043207;negative regulation of biological process#GO:0048519;activation of immune response#GO:0002253;humoral immune response#GO:0006959;lymphocyte mediated immunity#GO:0002449;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;adaptive immune response#GO:0002250;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;defense response#GO:0006952;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;leukocyte mediated immunity#GO:0002443;regulation of immune response#GO:0050776;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological regulation#GO:0065007;complement activation#GO:0006956 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=9163|UniProtKB=Q13519 Q13519 PNOC PTHR11438:SF2 PROENKEPHALIN PREPRONOCICEPTIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;axon terminus#GO:0043679;cell body#GO:0044297;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cell projection#GO:0042995;plasma membrane#GO:0005886 neuropeptide#PC00162 HUMAN|HGNC=23687|UniProtKB=Q5UAW9 Q5UAW9 GPR157 PTHR23112:SF12 G PROTEIN-COUPLED RECEPTOR 157-RELATED G-PROTEIN COUPLED RECEPTOR 157 G-protein coupled receptor#PC00021 HUMAN|HGNC=14139|UniProtKB=P0CG20 P0CG20 PRR35 PTHR14678:SF2 UNCHARACTERIZED PROLINE-RICH PROTEIN 35 HUMAN|HGNC=4755|UniProtKB=Q93079 Q93079 H2BC9 PTHR23428:SF309 HISTONE H2B HISTONE H2B TYPE 1-H nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=10743|UniProtKB=Q02383 Q02383 SEMG2 PTHR10547:SF6 SEMENOGELIN/SEMINAL VESICLE SECRETORY PROTEIN SEMENOGELIN-2 sperm capacitation#GO:0048240;germ cell development#GO:0007281;cellular developmental process#GO:0048869;male gamete generation#GO:0048232;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;spermatid differentiation#GO:0048515;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;anatomical structure development#GO:0048856;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 HUMAN|HGNC=14630|UniProtKB=Q96HD1 Q96HD1 CRELD1 PTHR24034:SF114 EGF-LIKE DOMAIN-CONTAINING PROTEIN PROTEIN DISULFIDE ISOMERASE CRELD1 extracellular matrix structural protein#PC00103 HUMAN|HGNC=17641|UniProtKB=Q9H816 Q9H816 DCLRE1B PTHR23240:SF26 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED 5' EXONUCLEASE APOLLO hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;damaged DNA binding#GO:0003684;exonuclease activity#GO:0004527;deoxyribonuclease activity#GO:0004536;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;exodeoxyribonuclease activity#GO:0004529;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;exodeoxyribonuclease activity, producing 5'-phosphomonoesters#GO:0016895 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;telomere capping#GO:0016233;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;chromosome organization#GO:0051276;organelle organization#GO:0006996;biological regulation#GO:0065007;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009 HUMAN|HGNC=3725|UniProtKB=O95302 O95302 FKBP9 PTHR46046:SF2 FAMILY NOT NAMED FK506-BINDING PROTEIN 9-LIKE PROTEIN-RELATED HUMAN|HGNC=18684|UniProtKB=Q9Y6V7 Q9Y6V7 DDX49 PTHR24031:SF240 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX49-RELATED HUMAN|HGNC=1958|UniProtKB=P43681 P43681 CHRNA4 PTHR18945:SF401 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;acetylcholine receptor activity#GO:0015464;molecular transducer activity#GO:0060089;acetylcholine binding#GO:0042166;ion binding#GO:0043167;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA4#P06594;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=11842|UniProtKB=Q86UE8 Q86UE8 TLK2 PTHR22974:SF20 MIXED LINEAGE PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE TOUSLED-LIKE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 chromatin assembly or disassembly#GO:0006333;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;chromosome segregation#GO:0007059;phosphate-containing compound metabolic process#GO:0006796;regulation of chromatin assembly or disassembly#GO:0001672;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of chromatin organization#GO:1902275;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;chromosome organization#GO:0051276;biological regulation#GO:0065007;chromatin organization#GO:0006325;peptidyl-serine modification#GO:0018209 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=29333|UniProtKB=Q8N2N9 Q8N2N9 ANKRD36B PTHR24147:SF50 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 36A-RELATED HUMAN|HGNC=7673|UniProtKB=Q9Y618 Q9Y618 NCOR2 PTHR13992:SF21 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR NUCLEAR RECEPTOR COREPRESSOR 2 binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;DNA-binding transcription factor binding#GO:0140297 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>N-CoR#P00770;Notch signaling pathway#P00045>CoR#P01112 HUMAN|HGNC=29406|UniProtKB=Q96N64 Q96N64 PWWP2A PTHR23068:SF4 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED PWWP DOMAIN-CONTAINING PROTEIN 2A DNA methyltransferase#PC00013 HUMAN|HGNC=13378|UniProtKB=Q9GZW8 Q9GZW8 MS4A7 PTHR23320:SF8 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 7 transporter#PC00227 HUMAN|HGNC=16510|UniProtKB=Q5XUX0 Q5XUX0 FBXO31 PTHR10706:SF155 F-BOX FAMILY PROTEIN F-BOX ONLY PROTEIN 31 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=11594|UniProtKB=Q96SF7 Q96SF7 TBX15 PTHR11267:SF98 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX15 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell fate commitment#GO:0045165;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=3670|UniProtKB=Q92913 Q92913 FGF13 PTHR11486:SF145 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 13 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=30801|UniProtKB=Q9UKB5 Q9UKB5 AJAP1 PTHR32422:SF0 ADHERENS JUNCTION-ASSOCIATED PROTEIN 1 ADHERENS JUNCTION-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 leaflet of membrane bilayer#GO:0097478;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;side of membrane#GO:0098552;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;cell-cell contact zone#GO:0044291;intrinsic component of plasma membrane#GO:0031226;adherens junction#GO:0005912;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 HUMAN|HGNC=29970|UniProtKB=Q7RTZ1 Q7RTZ1 OVCH2 PTHR24251:SF16 OVOCHYMASE-RELATED OVOCHYMASE-2 serine protease#PC00203 HUMAN|HGNC=4641|UniProtKB=P30711 P30711 GSTT1 PTHR43917:SF9 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE THETA-1 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=27501|UniProtKB=Q7Z3Q1 Q7Z3Q1 SLC46A3 PTHR23507:SF9 ZGC:174356 SOLUTE CARRIER FAMILY 46 MEMBER 3 HUMAN|HGNC=15448|UniProtKB=O00461 O00461 GOLIM4 PTHR22909:SF22 GOLGI INTEGRAL MEMBRANE PROTEIN 4 GOLGI INTEGRAL MEMBRANE PROTEIN 4 HUMAN|HGNC=16638|UniProtKB=Q8IYB3 Q8IYB3 SRRM1 PTHR23148:SF0 SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN SERINE/ARGININE REPETITIVE MATRIX PROTEIN 1 RNA processing factor#PC00147 HUMAN|HGNC=12227|UniProtKB=A0A0J9YXY3 A0A0J9YXY3 TRBV6-2 PTHR23268:SF19 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 6-2-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=33276|UniProtKB=Q5D862 Q5D862 FLG2 PTHR22571:SF24 FILAGGRIN-RELATED FILAGGRIN-2 system development#GO:0048731;multicellular organismal homeostasis#GO:0048871;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of body fluid levels#GO:0050878;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;skin development#GO:0043588 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=29127|UniProtKB=O94915 O94915 FRYL PTHR12295:SF9 FURRY-RELATED PROTEIN FURRY HOMOLOG-LIKE cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular#GO:0005622;site of polarized growth#GO:0030427 scaffold/adaptor protein#PC00226 HUMAN|HGNC=32224|UniProtKB=Q0VD86 Q0VD86 INCA1 PTHR37341:SF1 PROTEIN INCA1 PROTEIN INCA1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;cell population proliferation#GO:0008283;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of cyclin-dependent protein kinase activity#GO:1904029;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of cell population proliferation#GO:0008285;phosphorylation#GO:0016310;negative regulation of transferase activity#GO:0051348;protein metabolic process#GO:0019538;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of protein kinase activity#GO:0045859;regulation of cell population proliferation#GO:0042127;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=1001|UniProtKB=P41182 P41182 BCL6 PTHR24399:SF29 ZINC FINGER AND BTB DOMAIN-CONTAINING B-CELL LYMPHOMA 6 PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=33768|UniProtKB=Q6UWT4 Q6UWT4 C5orf46 PTHR37864:SF1 SIMILAR TO AVLV472 SIMILAR TO AVLV472 HUMAN|HGNC=33939|UniProtKB=A0PK11 A0PK11 CLRN2 PTHR31548:SF5 CLARIN CLARIN-2 HUMAN|HGNC=7128|UniProtKB=Q9UHC1 Q9UHC1 MLH3 PTHR10073:SF47 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL DNA MISMATCH REPAIR PROTEIN MLH3 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;intracellular#GO:0005622;DNA repair complex#GO:1990391 DNA metabolism protein#PC00009 HUMAN|HGNC=33627|UniProtKB=Q8NCU7 Q8NCU7 C2CD4A PTHR47226:SF3 C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4A C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4A HUMAN|HGNC=2949|UniProtKB=Q8TD57 Q8TD57 DNAH3 PTHR10676:SF242 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN 3, AXONEMAL pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement#GO:0003341 supramolecular complex#GO:0099080;axoneme#GO:0005930;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=12994|UniProtKB=O95125 O95125 ZNF202 PTHR23226:SF195 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 202 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7468|UniProtKB=Q99707 Q99707 MTR PTHR45833:SF1 METHIONINE SYNTHASE METHIONINE SYNTHASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 S-adenosylmethionine biosynthesis#P02773>Cobalamin-dependent homocysteine transmethylase#P03142;Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024;Formyltetrahydroformate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953 HUMAN|Ensembl=ENSG00000276289|UniProtKB=A0A087WTH5 A0A087WTH5 KCNE1B PTHR15282:SF10 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1-RELATED cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;protein binding#GO:0005515;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 blood circulation#GO:0008015;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of metal ion transport#GO:0010959;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;action potential#GO:0001508;regulation of localization#GO:0032879;regulation of system process#GO:0044057;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;actin-mediated cell contraction#GO:0070252;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;actin filament-based process#GO:0030029;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;monovalent inorganic cation transport#GO:0015672;regulation of multicellular organismal process#GO:0051239;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of heart contraction#GO:0008016;ion transport#GO:0006811;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;regulation of membrane potential#GO:0042391;negative regulation of transport#GO:0051051;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;export from cell#GO:0140352;heart process#GO:0003015;muscle contraction#GO:0006936;negative regulation of molecular function#GO:0044092 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=10582|UniProtKB=Q9Y5Y9 Q9Y5Y9 SCN10A PTHR10037:SF208 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 10 SUBUNIT ALPHA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sodium channel activity#GO:0005272;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 blood circulation#GO:0008015;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;action potential#GO:0001508;regulation of system process#GO:0044057;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;ion homeostasis#GO:0050801;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of multicellular organismal process#GO:0051239;transmembrane transport#GO:0055085;regulation of heart contraction#GO:0008016;ion transport#GO:0006811;regulation of membrane potential#GO:0042391;heart contraction#GO:0060047;trans-synaptic signaling#GO:0099537;homeostatic process#GO:0042592;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;chemical homeostasis#GO:0048878;circulatory system process#GO:0003013;ion transmembrane transport#GO:0034220;localization#GO:0051179;sodium ion transport#GO:0006814;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart process#GO:0003015;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=29558|UniProtKB=Q9H093 Q9H093 NUAK2 PTHR24343:SF133 SERINE/THREONINE KINASE NUAK FAMILY SNF1-LIKE KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=28712|UniProtKB=Q8N412 Q8N412 STPG2 PTHR21580:SF52 SHIPPO-1-RELATED SPERM-TAIL PG-RICH REPEAT-CONTAINING PROTEIN 2 structural protein#PC00211 HUMAN|HGNC=28230|UniProtKB=Q9BRT3 Q9BRT3 MIEN1 PTHR15124:SF15 SELENOPROTEIN W MIGRATION AND INVASION ENHANCER 1 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cell projection organization#GO:0030030;positive regulation of cell projection organization#GO:0031346;regulation of cellular component organization#GO:0051128;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of cellular component biogenesis#GO:0044087;apoptotic process#GO:0006915;cell death#GO:0008219;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;cellular component assembly#GO:0022607;response to inorganic substance#GO:0010035;regulation of apoptotic process#GO:0042981;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;programmed cell death#GO:0012501;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cell projection assembly#GO:0030031;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;negative regulation of cell death#GO:0060548;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell death#GO:0010941;plasma membrane bounded cell projection assembly#GO:0120031 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=23758|UniProtKB=Q8IUS5 Q8IUS5 EPHX4 PTHR43329:SF2 EPOXIDE HYDROLASE EPOXIDE HYDROLASE 4 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=21555|UniProtKB=Q5T1H1 Q5T1H1 EYS PTHR24033:SF186 EGF-LIKE DOMAIN-CONTAINING PROTEIN PROTEIN EYES SHUT HOMOLOG HUMAN|HGNC=11969|UniProtKB=Q8NDV7 Q8NDV7 TNRC6A PTHR13020:SF28 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6A PROTEIN negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;posttranscriptional gene silencing#GO:0016441;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;gene silencing by miRNA#GO:0035195;nuclear-transcribed mRNA catabolic process#GO:0000956;gene silencing by RNA#GO:0031047;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254;cellular macromolecule catabolic process#GO:0044265 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=370|UniProtKB=Q02952 Q02952 AKAP12 PTHR23209:SF4 A-KINASE ANCHOR PROTEIN 12 A-KINASE ANCHOR PROTEIN 12 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26379|UniProtKB=Q8N7B9 Q8N7B9 EFCAB3 PTHR47500:SF2 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 3 calmodulin-related#PC00061 HUMAN|HGNC=14193|UniProtKB=Q9NZN5 Q9NZN5 ARHGEF12 PTHR45872:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 12 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=32370|UniProtKB=Q14439 Q14439 GPR176 PTHR22752:SF1 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 176 G-protein coupled receptor#PC00021 HUMAN|HGNC=179|UniProtKB=P07311 P07311 ACYP1 PTHR10029:SF21 ACYLPHOSPHATASE ACYLPHOSPHATASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 phosphatase#PC00181 HUMAN|HGNC=7406|UniProtKB=P02795 P02795 MT2A PTHR23299:SF22 METALLOTHIONEIN METALLOTHIONEIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;transition metal ion homeostasis#GO:0055076;response to metal ion#GO:0010038;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;response to toxic substance#GO:0009636;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25587|UniProtKB=Q9NVA4 Q9NVA4 TMEM184C PTHR23423:SF10 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184C localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=20807|UniProtKB=Q96H40 Q96H40 ZNF486 PTHR24384:SF95 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 486-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=14175|UniProtKB=Q9UJK0 Q9UJK0 TSR3 PTHR20426:SF0 RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG 18S RRNA AMINOCARBOXYPROPYLTRANSFERASE cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=11938|UniProtKB=P32971 P32971 TNFSF8 PTHR32163:SF1 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 8 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 8 alpha-beta T cell differentiation#GO:0046632;cellular developmental process#GO:0048869;lymphocyte activation#GO:0046649;immune system development#GO:0002520;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;cellular process#GO:0009987;T cell differentiation#GO:0030217;cell activation#GO:0001775;system development#GO:0048731;immune system process#GO:0002376;cell differentiation#GO:0030154;lymphocyte differentiation#GO:0030098;leukocyte differentiation#GO:0002521;T cell activation#GO:0042110;anatomical structure development#GO:0048856;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;leukocyte activation#GO:0045321 HUMAN|HGNC=8260|UniProtKB=O76002 O76002 OR2J2 PTHR26453:SF318 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2J2 transmembrane signal receptor#PC00197 HUMAN|HGNC=28386|UniProtKB=Q96KX1 Q96KX1 C4orf36 PTHR38002:SF1 C4ORF36 ISOFORM 11 CHROMOSOME 4 C4ORF36 HOMOLOG HUMAN|HGNC=25310|UniProtKB=Q96NW4 Q96NW4 ANKRD27 PTHR24170:SF1 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;SNARE binding#GO:0000149;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;retrograde transport, endosome to plasma membrane#GO:1990126;cellular process#GO:0009987;cytosolic transport#GO:0016482 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=7993|UniProtKB=Q9UHY1 Q9UHY1 NRBP1 PTHR13902:SF48 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;protein phosphorylation#GO:0006468;cell communication#GO:0007154;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=37321|UniProtKB=A0A1B0GVH4 A0A1B0GVH4 PRSS51 PTHR24253:SF132 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE-LIKE PROTEIN 51 serine protease#PC00203 HUMAN|HGNC=4524|UniProtKB=Q8TCW9 Q8TCW9 PROKR1 PTHR24241:SF137 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PROKINETICIN RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=16527|UniProtKB=Q8TDI7 Q8TDI7 TMC2 PTHR23302:SF17 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;sensory perception of sound#GO:0007605;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;response to abiotic stimulus#GO:0009628 HUMAN|HGNC=4665|UniProtKB=Q8WUA4 Q8WUA4 GTF3C2 PTHR15052:SF2 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR COMPLEX SUBUNIT GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 2 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 HUMAN|HGNC=433|UniProtKB=P16050 P16050 ALOX15 PTHR11771:SF33 LIPOXYGENASE POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX15 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;oxidation-reduction process#GO:0055114;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 oxygenase#PC00177 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830;Gonadotropin-releasing hormone receptor pathway#P06664>12-LO#P06815 HUMAN|HGNC=23093|UniProtKB=Q8NCK7 Q8NCK7 SLC16A11 PTHR11360:SF80 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 11 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=28737|UniProtKB=Q8IXM2 Q8IXM2 BAP18 PTHR21397:SF2 CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED CHROMATIN COMPLEXES SUBUNIT BAP18 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=12593|UniProtKB=P22415 P22415 USF1 PTHR46117:SF1 FI24210P1 UPSTREAM STIMULATORY FACTOR 1 HUMAN|HGNC=2237|UniProtKB=Q9UBF2 Q9UBF2 COPG2 PTHR10261:SF4 COATOMER SUBUNIT GAMMA COATOMER SUBUNIT GAMMA-2 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;organelle localization#GO:0051640;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of organelle localization#GO:0051656;secretion by cell#GO:0032940;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport along microtubule#GO:0010970;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;organelle transport along microtubule#GO:0072384;export from cell#GO:0140352 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;COPI vesicle coat#GO:0030126;intracellular#GO:0005622;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=15968|UniProtKB=Q8TB36 Q8TB36 GDAP1 PTHR44188:SF3 GDAP1, ISOFORM A GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 1 mitochondrial fusion#GO:0008053;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;organelle fusion#GO:0048284;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;peptide transport#GO:0015833;protein localization#GO:0008104;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular transport#GO:0046907;mitochondrial fission#GO:0000266 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;integral component of mitochondrial outer membrane#GO:0031307 HUMAN|HGNC=19223|UniProtKB=P56851 P56851 EDDM3B PTHR16788:SF0 EPIDIDYMAL SECRETORY PROTEIN E3 ALPHA EPIDIDYMAL SECRETORY PROTEIN E3-BETA HUMAN|HGNC=28279|UniProtKB=Q8WVP5 Q8WVP5 TNFAIP8L1 PTHR12757:SF2 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=3961|UniProtKB=Q9NQT6 Q9NQT6 FSCN3 PTHR10551:SF1 FASCIN FASCIN-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament bundle assembly#GO:0051017;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=10563|UniProtKB=O15126 O15126 SCAMP1 PTHR10687:SF8 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 1 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 HUMAN|HGNC=3527|UniProtKB=Q15910 Q15910 EZH2 PTHR45747:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) HISTONE-LYSINE N-METHYLTRANSFERASE EZH2 histone modifying enzyme#PC00261 HUMAN|HGNC=24170|UniProtKB=Q8TDN6 Q8TDN6 BRIX1 PTHR13634:SF0 RIBOSOME BIOGENESIS PROTEIN BRIX RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=18325|UniProtKB=Q2WGN9 Q2WGN9 GAB4 PTHR45960:SF4 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 4 scaffold/adaptor protein#PC00226 HUMAN|HGNC=37444|UniProtKB=Q8N7Z2 Q8N7Z2 GOLGA6L1 PTHR23143:SF20 TRICHOHYALIN-RELATED GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 1-RELATED actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=11771|UniProtKB=Q15582 Q15582 TGFBI PTHR10900:SF82 PERIOSTIN-RELATED TRANSFORMING GROWTH FACTOR-BETA-INDUCED PROTEIN IG-H3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;biological adhesion#GO:0022610 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cell adhesion molecule#PC00069 HUMAN|HGNC=26067|UniProtKB=Q5TAA0 Q5TAA0 TTC22 PTHR16253:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 22 TETRATRICOPEPTIDE REPEAT PROTEIN 22 HUMAN|HGNC=17297|UniProtKB=Q969K3 Q969K3 RNF34 PTHR14879:SF3 CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF34 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;regulation of apoptotic signaling pathway#GO:2001233;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;plasma membrane bounded cell projection organization#GO:0120036;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of apoptotic signaling pathway#GO:2001234;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;negative regulation of signaling#GO:0023057;negative regulation of endopeptidase activity#GO:0010951;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043154;negative regulation of signal transduction#GO:0009968;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;plasma membrane bounded cell projection assembly#GO:0120031;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;execution phase of apoptosis#GO:0097194;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cell projection assembly#GO:0030031;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=16513|UniProtKB=Q8TDI8 Q8TDI8 TMC1 PTHR23302:SF18 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215 response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;sensory perception of sound#GO:0007605;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;response to abiotic stimulus#GO:0009628 HUMAN|HGNC=25720|UniProtKB=Q96I76 Q96I76 GPATCH3 PTHR14390:SF2 G PATCH DOMAIN CONTAINING PROTEIN 3 G PATCH DOMAIN-CONTAINING PROTEIN 3 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=13125|UniProtKB=Q68EA5 Q68EA5 ZNF57 PTHR24379:SF9 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 57 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=14894|UniProtKB=Q9BZM5 Q9BZM5 ULBP2 PTHR16675:SF148 MHC CLASS I-RELATED UL16-BINDING PROTEIN 2-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=34405|UniProtKB=A6NIL9 A6NIL9 CRYM-AS1 PTHR19229:SF100 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=24015|UniProtKB=Q7Z4G1 Q7Z4G1 COMMD6 PTHR16231:SF5 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 6 HUMAN|HGNC=12107|UniProtKB=A0A0B4J271 A0A0B4J271 TRAV12-3 PTHR19343:SF12 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 12-3 HUMAN|HGNC=31966|UniProtKB=Q2HXU8 Q2HXU8 CLEC12B PTHR47647:SF1 C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER B C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER B phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;binding#GO:0005488 immune response-regulating signaling pathway#GO:0002764;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;immune response#GO:0006955;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;immune system process#GO:0002376;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;signaling#GO:0023052;negative regulation of molecular function#GO:0044092 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=25215|UniProtKB=Q6UXB3 Q6UXB3 LYPD2 PTHR10036:SF11 CD59 GLYCOPROTEIN LY6/PLAUR DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=1585|UniProtKB=P30281 P30281 CCND3 PTHR10177:SF65 CYCLINS G1/S-SPECIFIC CYCLIN-D3 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of mitotic cell cycle#GO:0045931;regulation of G1/S transition of mitotic cell cycle#GO:2000045;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of phosphate metabolic process#GO:0019220;regulation of cyclin-dependent protein kinase activity#GO:1904029;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of cell cycle process#GO:0090068;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of protein kinase activity#GO:0045859;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of mitotic cell cycle#GO:0007346;regulation of transferase activity#GO:0051338 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 Cell cycle#P00013>Cyclin D#P00484 HUMAN|HGNC=28520|UniProtKB=Q8NHR7 Q8NHR7 TERB2 PTHR35345:SF1 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 2 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 2 cellular localization#GO:0051641;organelle localization#GO:0051640;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;chromosome segregation#GO:0007059;M phase#GO:0000279;chromosome organization involved in meiotic cell cycle#GO:0070192;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle phase#GO:0022403;establishment of organelle localization#GO:0051656;meiosis I#GO:0007127;meiosis I cell cycle phase#GO:0098764;nuclear chromosome segregation#GO:0098813;establishment of chromosome localization#GO:0051303;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;biological phase#GO:0044848;chromosome localization#GO:0050000 membrane-enclosed lumen#GO:0031974;envelope#GO:0031975;nuclear chromosome, telomeric region#GO:0000784;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;chromosome, telomeric region#GO:0000781;chromosome#GO:0005694;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981;plasma membrane#GO:0005886 HUMAN|HGNC=1255|UniProtKB=O95447 O95447 LCA5L PTHR16650:SF9 C21ORF13-RELATED LEBERCILIN-LIKE PROTEIN microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=23261|UniProtKB=Q6ZRK6 Q6ZRK6 CCDC73 PTHR28660:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 73 COILED-COIL DOMAIN-CONTAINING PROTEIN 73 HUMAN|HGNC=9811|UniProtKB=O60216 O60216 RAD21 PTHR12585:SF20 SCC1 / RAD21 FAMILY MEMBER DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21 HOMOLOG chromatin binding#GO:0003682;binding#GO:0005488 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;double-strand break repair#GO:0006302;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;meiotic sister chromatid segregation#GO:0045144;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;M phase#GO:0000279;sister chromatid cohesion#GO:0007062;chromosome organization involved in meiotic cell cycle#GO:0070192;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;meiosis I cell cycle phase#GO:0098764;cellular response to stimulus#GO:0051716;mitotic sister chromatid cohesion#GO:0007064;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=145|UniProtKB=P63267 P63267 ACTG2 PTHR11937:SF201 ACTIN ACTIN, GAMMA-ENTERIC SMOOTH MUSCLE regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;regulation of biological quality#GO:0065008;smooth muscle contraction#GO:0006939;system process#GO:0003008;biological regulation#GO:0065007;regulation of blood vessel diameter#GO:0097746;multicellular organismal process#GO:0032501;circulatory system process#GO:0003013;muscle system process#GO:0003012;muscle contraction#GO:0006936 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 HUMAN|HGNC=24971|UniProtKB=Q9P127 Q9P127 LUZP4 PTHR22550:SF5 SPORE GERMINATION PROTEIN LEUCINE ZIPPER PROTEIN 4 HUMAN|HGNC=19360|UniProtKB=Q53G59 Q53G59 KLHL12 PTHR24412:SF455 KELCH PROTEIN KELCH-LIKE PROTEIN 12 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17046|UniProtKB=Q969F2 Q969F2 NKD2 PTHR22611:SF1 PROTEIN NAKED CUTICLE PROTEIN NAKED CUTICLE HOMOLOG 2 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cell communication#GO:0010648;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Wnt signaling pathway#P00057>Naked#P01427 HUMAN|HGNC=11313|UniProtKB=P10155 P10155 RO60 PTHR14202:SF0 60 KDA RIBONUCLEOPROTEIN SSA/RO 60 KDA SS-A/RO RIBONUCLEOPROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 HUMAN|HGNC=1875|UniProtKB=Q9Y281 Q9Y281 CFL2 PTHR11913:SF15 COFILIN-RELATED COFILIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 protein-containing complex disassembly#GO:0032984;cellular protein complex disassembly#GO:0043624;actin polymerization or depolymerization#GO:0008154;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;locomotion#GO:0040011;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;actin cortical patch#GO:0030479;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Cofilin#P00508 HUMAN|HGNC=29597|UniProtKB=A1A4Y4 A1A4Y4 IRGM PTHR32341:SF9 INTERFERON-INDUCIBLE GTPASE IMMUNITY-RELATED GTPASE FAMILY M PROTEIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 response to organic substance#GO:0010033;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to chemical#GO:0042221;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to cytokine stimulus#GO:0071345;cellular response to organic substance#GO:0071310;defense response#GO:0006952;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=23192|UniProtKB=Q9H5L6 Q9H5L6 THAP9 PTHR10725:SF32 THAP DOMAIN-CONTAINING PROTEIN 9 DNA TRANSPOSASE THAP9 HUMAN|HGNC=23094|UniProtKB=Q6ZSM3 Q6ZSM3 SLC16A12 PTHR11360:SF28 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 12 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=23805|UniProtKB=Q76L83 Q76L83 ASXL2 PTHR13578:SF11 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL2-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=8772|UniProtKB=Q9Y233 Q9Y233 PDE10A PTHR11347:SF111 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP AND CAMP-INHIBITED CGMP 3',5'-CYCLIC PHOSPHODIESTERASE 10A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;second-messenger-mediated signaling#GO:0019932;negative regulation of response to stimulus#GO:0048585;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 HUMAN|HGNC=31455|UniProtKB=Q5JTZ5 Q5JTZ5 C9orf152 PTHR36290:SF1 RIKEN CDNA D630039A03 GENE DUF4682 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=17035|UniProtKB=Q96B26 Q96B26 EXOSC8 PTHR11097:SF9 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP43 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;modification-dependent macromolecule catabolic process#GO:0043632;mRNA 3'-end processing#GO:0031124;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;mRNA catabolic process#GO:0006402;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;snRNA processing#GO:0016180;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;maturation of 5.8S rRNA#GO:0000460;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;cleavage involved in rRNA processing#GO:0000469;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;snRNA metabolic process#GO:0016073;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA polyadenylation#GO:0006378;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;nucleic acid phosphodiester bond hydrolysis#GO:0090305;rRNA metabolic process#GO:0016072;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;exosome (RNase complex)#GO:0000178;intracellular organelle#GO:0043229 exoribonuclease#PC00099 HUMAN|HGNC=6270|UniProtKB=Q92806 Q92806 KCNJ9 PTHR11767:SF17 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083 HUMAN|HGNC=18175|UniProtKB=Q9NZJ6 Q9NZJ6 COQ3 PTHR43464:SF19 METHYLTRANSFERASE UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL methyltransferase#PC00155 HUMAN|HGNC=8186|UniProtKB=P58170 P58170 OR1D5 PTHR48001:SF70 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1D4-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=8683|UniProtKB=Q9Y5F1 Q9Y5F1 PCDHB12 PTHR24028:SF118 CADHERIN-87A PROTOCADHERIN BETA-12 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=29229|UniProtKB=Q9ULI1 Q9ULI1 NWD2 PTHR19857:SF18 MITOCHONDRIAL DIVISION PROTEIN 1-RELATED NACHT AND WD REPEAT DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=6827|UniProtKB=Q9NTJ4 Q9NTJ4 MAN2C1 PTHR46017:SF1 ALPHA-MANNOSIDASE 2C1 ALPHA-MANNOSIDASE 2C1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 HUMAN|HGNC=29123|UniProtKB=Q9Y4B4 Q9Y4B4 RAD54L2 PTHR45797:SF1 RAD54-LIKE HELICASE ARIP4 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=7166|UniProtKB=P08253 P08253 MMP2 PTHR10201:SF29 MATRIX METALLOPROTEINASE 72 KDA TYPE IV COLLAGENASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 tissue remodeling#GO:0048771;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to hypoxia#GO:0001666;extracellular structure organization#GO:0043062;response to stress#GO:0006950;response to decreased oxygen levels#GO:0036293;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;response to oxygen levels#GO:0070482;metabolic process#GO:0008152 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=20226|UniProtKB=Q9ULI4 Q9ULI4 KIF26A PTHR24115:SF407 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF26A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=12129|UniProtKB=A0A087WSZ9 A0A087WSZ9 TRAV30 PTHR19433:SF120 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 30 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=9178|UniProtKB=P56282 P56282 POLE2 PTHR12708:SF0 DNA POLYMERASE EPSILON SUBUNIT B DNA POLYMERASE EPSILON SUBUNIT 2 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;DNA polymerase complex#GO:0042575;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-directed DNA polymerase#PC00018 HUMAN|HGNC=14996|UniProtKB=Q8NGY1 Q8NGY1 OR10Z1 PTHR26451:SF49 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10Z1 HUMAN|HGNC=21723|UniProtKB=Q8NHE4 Q8NHE4 ATP6V0E2 PTHR12263:SF2 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT E 2 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 ATP synthase#PC00002 HUMAN|HGNC=20154|UniProtKB=Q8TB40 Q8TB40 ABHD4 PTHR42886:SF21 RE40534P-RELATED (LYSO)-N-ACYLPHOSPHATIDYLETHANOLAMINE LIPASE transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;transferase activity#GO:0016740;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;regulation of biological quality#GO:0065008;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=20997|UniProtKB=Q9H091 Q9H091 ZMYND15 PTHR47085:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 15 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 15 HUMAN|HGNC=21055|UniProtKB=Q6UB35 Q6UB35 MTHFD1L PTHR48099:SF12 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED MONOFUNCTIONAL C1-TETRAHYDROFOLATE SYNTHASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;pteridine-containing compound metabolic process#GO:0042558;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Formyltetrahydroformate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 HUMAN|HGNC=3095|UniProtKB=Q9NR20 Q9NR20 DYRK4 PTHR24058:SF22 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14211|UniProtKB=Q8WV28 Q8WV28 BLNK PTHR14098:SF3 SH2 DOMAIN CONTAINING PROTEIN B-CELL LINKER PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 scaffold/adaptor protein#PC00226 B cell activation#P00010>BLNK#P00394 HUMAN|HGNC=12388|UniProtKB=Q16762 Q16762 TST PTHR11364:SF6 THIOSULFATE SULFERTANSFERASE THIOSULFATE SULFURTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid metabolic process#GO:0006520;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transferase#PC00220 HUMAN|HGNC=33518|UniProtKB=Q96QU4 Q96QU4 FRG2B PTHR31883:SF7 PROTEIN FRG2-RELATED PROTEIN FRG2-RELATED HUMAN|HGNC=13890|UniProtKB=Q96J02 Q96J02 ITCH PTHR11254:SF66 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE ITCHY HOMOLOG positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222;protein K63-linked ubiquitination#GO:0070534 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 HUMAN|HGNC=6402|UniProtKB=O00410 O00410 IPO5 PTHR10527:SF22 IMPORTIN BETA IMPORTIN-5 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=408|UniProtKB=P51649 P51649 ALDH5A1 PTHR43353:SF5 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402;Aminobutyrate degradation#P02726>Succinate semi-aldehyde dehydrogenase#P02824;Gamma-aminobutyric acid synthesis#P04384>Succinic semialdehyde dehydrogenase#P04481 HUMAN|HGNC=2488|UniProtKB=P52952 P52952 NKX2-5 PTHR24340:SF28 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=27034|UniProtKB=Q8N434 Q8N434 SVOPL PTHR24064:SF457 SOLUTE CARRIER FAMILY 22 MEMBER TRANSPORTER SVOPL-RELATED secondary carrier transporter#PC00258 HUMAN|HGNC=25773|UniProtKB=Q9H967 Q9H967 WDR76 PTHR14773:SF0 UNCHARACTERIZED WD REPEAT-CONTAINING PROTEIN 76 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;regulation of response to DNA damage stimulus#GO:2001020;negative regulation of cell cycle#GO:0045786;regulation of response to stress#GO:0080134;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular response to stress#GO:0080135;cell cycle checkpoint#GO:0000075;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;DNA damage checkpoint#GO:0000077;cellular response to stress#GO:0033554;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12633|UniProtKB=O00507 O00507 USP9Y PTHR24006:SF693 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE FAF-Y-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell motility#GO:0048870;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;localization#GO:0051179;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;movement of cell or subcellular component#GO:0006928;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;cell migration#GO:0016477;protein metabolic process#GO:0019538;locomotion#GO:0040011;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=34059|UniProtKB=A6NLX4 A6NLX4 TMEM210 PTHR39234:SF1 TRANSMEMBRANE PROTEIN 210 TRANSMEMBRANE PROTEIN 210 HUMAN|HGNC=12531|UniProtKB=Q9HAW8 Q9HAW8 UGT1A10 PTHR48050:SF6 STEROL 3-BETA-GLUCOSYLTRANSFERASE UDP-GLUCURONOSYLTRANSFERASE 1A10-RELATED glycosyltransferase#PC00111 HUMAN|HGNC=800|UniProtKB=P50993 P50993 ATP1A2 PTHR43294:SF6 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-2 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;potassium ion transport#GO:0006813;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;cellular monovalent inorganic cation homeostasis#GO:0030004;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725;export from cell#GO:0140352 primary active transporter#PC00068 HUMAN|HGNC=12992|UniProtKB=P17024 P17024 ZNF20 PTHR24381:SF244 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 20-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=12687|UniProtKB=P40337 P40337 VHL PTHR15160:SF1 VON HIPPEL-LINDAU PROTEIN VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR ubiquitin-protein ligase#PC00234 Hypoxia response via HIF activation#P00030>VHL#P00816 HUMAN|HGNC=5966|UniProtKB=P20809 P20809 IL11 PTHR16922:SF0 INTERLEUKIN 11 INTERLEUKIN-11 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Interleukin#P00970 HUMAN|HGNC=14108|UniProtKB=Q9UIA9 Q9UIA9 XPO7 PTHR12596:SF11 EXPORTIN 4,7-RELATED EXPORTIN-7 transporter activity#GO:0005215 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;nuclear transport#GO:0051169 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=1610|UniProtKB=P51686 P51686 CCR9 PTHR10489:SF664 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 9 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=24049|UniProtKB=Q96L15 Q96L15 ART5 PTHR10339:SF2 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 5 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=2312|UniProtKB=P15169 P15169 CPN1 PTHR11532:SF80 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE N CATALYTIC CHAIN hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190 HUMAN|HGNC=9123|UniProtKB=A4D2B8 A4D2B8 PMS2P1 PTHR10073:SF52 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MISMATCH REPAIR ENDONUCLEASE PMS2-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=29685|UniProtKB=Q9NSE4 Q9NSE4 IARS2 PTHR42765:SF1 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=2857|UniProtKB=Q13574 Q13574 DGKZ PTHR11255:SF43 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ZETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;regulation of signaling#GO:0023051;lipid modification#GO:0030258;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;trans-synaptic signaling#GO:0099537;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cellular lipid metabolic process#GO:0044255 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 kinase#PC00137 Gonadotropin-releasing hormone receptor pathway#P06664>DGK-zeta#P06790 HUMAN|HGNC=20756|UniProtKB=Q7Z3T8 Q7Z3T8 ZFYVE16 PTHR46319:SF1 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 16 endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of protein localization to vacuole#GO:0072666;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;protein targeting to lysosome#GO:0006622;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 TGF-beta signaling pathway#P00052>SARA#P01281 HUMAN|HGNC=5217|UniProtKB=P14060 P14060 HSD3B1 PTHR10366:SF378 NAD DEPENDENT EPIMERASE/DEHYDRATASE 3 BETA-HYDROXYSTEROID DEHYDROGENASE/DELTA 5--4-ISOMERASE TYPE 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091 HUMAN|HGNC=4711|UniProtKB=P49863 P49863 GZMK PTHR24271:SF52 KALLIKREIN-RELATED GRANZYME K serine protease#PC00203 HUMAN|HGNC=35465|UniProtKB=P0CI01 P0CI01 SPDYE6 PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=51242|UniProtKB=P0DMR2 P0DMR2 SCGB1C2 PTHR10136:SF8 SECRETOGLOBIN FAMILY 1 MEMBER SECRETOGLOBIN FAMILY 1C MEMBER 1-RELATED cytokine#PC00083 HUMAN|HGNC=8984|UniProtKB=Q9UBF8 Q9UBF8 PI4KB PTHR10048:SF22 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;phosphatidylinositol phosphorylation#GO:0046854;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 kinase#PC00137 HUMAN|HGNC=18394|UniProtKB=Q8TD33 Q8TD33 SCGB1C1 PTHR10136:SF8 SECRETOGLOBIN FAMILY 1 MEMBER SECRETOGLOBIN FAMILY 1C MEMBER 1-RELATED cytokine#PC00083 HUMAN|HGNC=17817|UniProtKB=Q53G44 Q53G44 IFI44L PTHR14241:SF2 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44-LIKE HUMAN|HGNC=10848|UniProtKB=Q15465 Q15465 SHH PTHR11889:SF36 HEDGEHOG SONIC HEDGEHOG PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;gene expression#GO:0010467;cell communication#GO:0007154;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;signaling#GO:0023052;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 Hedgehog signaling pathway#P00025>Hedgehog#P00688 HUMAN|HGNC=1790|UniProtKB=P55273 P55273 CDKN2D PTHR24201:SF7 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR D p53 pathway#P00059>ARF#G01574;p53 pathway#P00059>ARF#P01482 HUMAN|HGNC=13993|UniProtKB=Q9NQV8 Q9NQV8 PRDM8 PTHR16516:SF7 AGAP007109-PA PR DOMAIN ZINC FINGER PROTEIN 8 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26080|UniProtKB=Q53H64 Q53H64 ANKRD40CL PTHR24192:SF2 ANKYRIN REPEAT DOMAIN 40 ANKRD40 C-TERMINAL-LIKE PROTEIN-RELATED HUMAN|HGNC=7967|UniProtKB=Q96RI1 Q96RI1 NR1H4 PTHR24082:SF155 NUCLEAR HORMONE RECEPTOR BILE ACID RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of inflammatory response#GO:0050728;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;inflammatory response#GO:0006954;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of inflammatory response#GO:0050727;negative regulation of macromolecule biosynthetic process#GO:0010558;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=28793|UniProtKB=O95568 O95568 METTL18 PTHR14614:SF39 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG HUMAN|HGNC=9465|UniProtKB=P11908 P11908 PRPS2 PTHR10210:SF110 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172 HUMAN|HGNC=41913|UniProtKB=Q96HG1 Q96HG1 SMIM10 PTHR34446:SF4 SMALL INTEGRAL MEMBRANE PROTEIN 10 SMALL INTEGRAL MEMBRANE PROTEIN 10 HUMAN|HGNC=7469|UniProtKB=O75570 O75570 MTRF1 PTHR43804:SF1 LD18447P PEPTIDE CHAIN RELEASE FACTOR 1, MITOCHONDRIAL cellular protein complex disassembly#GO:0043624;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;translational termination#GO:0006415;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;mitochondrial translation#GO:0032543;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 translation release factor#PC00225 HUMAN|HGNC=8178|UniProtKB=P58182 P58182 OR12D2 PTHR26451:SF52 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 12D2 HUMAN|HGNC=11796|UniProtKB=P10827 P10827 THRA PTHR24082:SF42 NUCLEAR HORMONE RECEPTOR THYROID HORMONE RECEPTOR ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=17090|UniProtKB=Q6ZSZ5 Q6ZSZ5 ARHGEF18 PTHR13944:SF23 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 18 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;Rho protein signal transduction#GO:0007266;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;regulation of Ras protein signal transduction#GO:0046578;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=2945|UniProtKB=Q0VDD8 Q0VDD8 DNAH14 PTHR10676:SF356 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN 14, AXONEMAL pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156 HUMAN|HGNC=24247|UniProtKB=Q8IVS8 Q8IVS8 GLYCTK PTHR12227:SF0 GLYCERATE KINASE GLYCERATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 carbohydrate kinase#PC00065 HUMAN|HGNC=15016|UniProtKB=Q8NH00 Q8NH00 OR2T4 PTHR26453:SF316 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T4 transmembrane signal receptor#PC00197 HUMAN|HGNC=17885|UniProtKB=Q8NFT2 Q8NFT2 STEAP2 PTHR14239:SF6 DUDULIN-RELATED METALLOREDUCTASE STEAP2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;iron ion transmembrane transport#GO:0034755;localization#GO:0051179;establishment of localization#GO:0051234;oxidation-reduction process#GO:0055114;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;metabolic process#GO:0008152 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=21423|UniProtKB=Q9NXV2 Q9NXV2 KCTD5 PTHR14958:SF12 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD5 protein binding#GO:0005515;binding#GO:0005488 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 HUMAN|HGNC=29609|UniProtKB=Q9NPH0 Q9NPH0 ACP6 PTHR11567:SF110 ACID PHOSPHATASE-RELATED LYSOPHOSPHATIDIC ACID PHOSPHATASE TYPE 6 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 phosphatase#PC00181 HUMAN|HGNC=24318|UniProtKB=Q9P298 Q9P298 HIGD1B PTHR12297:SF9 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1B cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26705|UniProtKB=Q6UXN8 Q6UXN8 CLEC9A PTHR47727:SF1 C-TYPE LECTIN DOMAIN FAMILY 9 MEMBER A C-TYPE LECTIN DOMAIN FAMILY 9 MEMBER A localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;cellular component organization#GO:0016043;cellular process#GO:0009987 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|Ensembl=ENSG00000285480|UniProtKB=A0A2R8Y619 A0A2R8Y619 H2BE1 PTHR23428:SF318 HISTONE H2B HISTONE H2B TYPE 2-E1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=5124|UniProtKB=P31275 P31275 HOXC12 PTHR46440:SF2 HOMEOBOX PROTEIN HOX-D12-RELATED HOMEOBOX PROTEIN HOX-C12 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 homeodomain transcription factor#PC00119 HUMAN|HGNC=20363|UniProtKB=O15033 O15033 AREL1 PTHR11254:SF340 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE APOPTOSIS-RESISTANT E3 UBIQUITIN PROTEIN LIGASE 1 positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;negative regulation of programmed cell death#GO:0043069;proteolysis#GO:0006508;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;negative regulation of cell death#GO:0060548;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=19200|UniProtKB=Q7L190 Q7L190 DPPA4 PTHR16073:SF8 DCR DOMAIN-CONTAINING PROTEIN DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 4 HUMAN|HGNC=12867|UniProtKB=Q9Y2L8 Q9Y2L8 ZKSCAN5 PTHR24377:SF214 IP01015P-RELATED ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19176|UniProtKB=Q96DZ9 Q96DZ9 CMTM5 PTHR22776:SF26 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 5 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=7982|UniProtKB=Q92570 Q92570 NR4A3 PTHR24085:SF2 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;signaling receptor binding#GO:0005102;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;hormone receptor binding#GO:0051427 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;response to peptide hormone#GO:0043434;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;cellular response to peptide#GO:1901653;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=31290|UniProtKB=A6NET4 A6NET4 OR5K3 PTHR26452:SF247 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5K3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=3355|UniProtKB=Q07075 Q07075 ENPEP PTHR11533:SF242 PROTEASE M1 ZINC METALLOPROTEASE GLUTAMYL AMINOPEPTIDASE cation binding#GO:0043169;metallopeptidase activity#GO:0008237;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;peptide binding#GO:0042277;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;peptidase activity#GO:0008233;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=4452|UniProtKB=O75487 O75487 GPC4 PTHR10822:SF25 GLYPICAN GLYPICAN-4 receptor localization to synapse#GO:0097120;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of localization#GO:0032879;regulation of synapse organization#GO:0050807;synaptic membrane adhesion#GO:0099560;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;cell junction assembly#GO:0034329;protein localization to organelle#GO:0033365;regulation of protein localization#GO:0032880;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;regulation of protein localization to membrane#GO:1905475;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;cell adhesion#GO:0007155;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular macromolecule localization#GO:0070727;synapse assembly#GO:0007416;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;regulation of nervous system development#GO:0051960;cell junction organization#GO:0034330;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;regulation of cell junction assembly#GO:1901888;regulation of synapse structure or activity#GO:0050803;cell migration#GO:0016477;locomotion#GO:0040011;protein-containing complex localization#GO:0031503 cell junction#GO:0030054;cell surface#GO:0009986;extracellular matrix#GO:0031012;synapse#GO:0045202;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=24060|UniProtKB=Q96C74 Q96C74 ROPN1L PTHR14952:SF14 ROPPORIN-1-LIKE PROTEIN ROPPORIN-1-LIKE PROTEIN HUMAN|HGNC=579|UniProtKB=Q99767 Q99767 APBA2 PTHR12345:SF12 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 2 amyloid-beta binding#GO:0001540;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084;Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093 HUMAN|HGNC=27561|UniProtKB=Q7Z6J9 Q7Z6J9 TSEN54 PTHR21027:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 endoribonuclease#PC00094 HUMAN|HGNC=31230|UniProtKB=Q8NGT9 Q8NGT9 OR2A42 PTHR26453:SF115 OLFACTORY RECEPTOR G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=26748|UniProtKB=Q8N9E0 Q8N9E0 FAM133A PTHR31911:SF4 PROTEIN FAM133 PROTEIN FAM133A RNA metabolism protein#PC00031 HUMAN|HGNC=4886|UniProtKB=Q30201 Q30201 HFE PTHR16675:SF172 MHC CLASS I-RELATED HEREDITARY HEMOCHROMATOSIS PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 metal ion transport#GO:0030001;immune response#GO:0006955;regulation of metal ion transport#GO:0010959;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;cation transport#GO:0006812;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to stress#GO:0006950;regulation of transport#GO:0051049;establishment of localization#GO:0051234;response to starvation#GO:0042594;biological regulation#GO:0065007;iron ion transport#GO:0006826;regulation of ion transport#GO:0043269;transition metal ion transport#GO:0000041 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=4814|UniProtKB=O60229 O60229 KALRN PTHR22826:SF49 RHO GUANINE EXCHANGE FACTOR-RELATED KALIRIN guanyl-nucleotide exchange factor#PC00113 Huntington disease#P00029>Duo#P00773 HUMAN|HGNC=31682|UniProtKB=P85299 P85299 PRR5 PTHR32428:SF4 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED PROLINE-RICH PROTEIN 5 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;TOR signaling#GO:0031929 TORC2 complex#GO:0031932;protein-containing complex#GO:0032991;intracellular#GO:0005622 VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520;PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=20767|UniProtKB=Q53GG5 Q53GG5 PDLIM3 PTHR24214:SF7 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=263|UniProtKB=P29274 P29274 ADORA2A PTHR24246:SF47 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A2A G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 HUMAN|HGNC=10405|UniProtKB=P60866 P60866 RPS20 PTHR11700:SF37 30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER 40S RIBOSOMAL PROTEIN S20 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=18888|UniProtKB=Q7RTR8 Q7RTR8 TAS2R42 PTHR11394:SF70 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 42 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=4279|UniProtKB=P36382 P36382 GJA5 PTHR11984:SF13 CONNEXIN GAP JUNCTION ALPHA-5 PROTEIN gap junction#PC00105 HUMAN|HGNC=11151|UniProtKB=P09012 P09012 SNRPA PTHR10501:SF63 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;U1 snRNP#GO:0005685;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 mRNA splicing#P00058>U1#P01479 HUMAN|HGNC=11316|UniProtKB=P05455 P05455 SSB PTHR22792:SF102 LUPUS LA PROTEIN-RELATED LUPUS LA PROTEIN RNA metabolism protein#PC00031 HUMAN|HGNC=24381|UniProtKB=Q8TF08 Q8TF08 COX7B2 PTHR16716:SF1 CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 7B2, MITOCHONDRIAL oxidase#PC00175 HUMAN|HGNC=18246|UniProtKB=Q9Y2S2 Q9Y2S2 CRYL1 PTHR48075:SF1 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN LAMBDA-CRYSTALLIN HOMOLOG oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092 HUMAN|HGNC=18943|UniProtKB=Q3LI63 Q3LI63 KRTAP20-1 PTHR39653:SF4 KERATIN-ASSOCIATED PROTEIN 20-2 KERATIN-ASSOCIATED PROTEIN 20-1 HUMAN|HGNC=1915|UniProtKB=O14646 O14646 CHD1 PTHR45623:SF7 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1 HUMAN|HGNC=24819|UniProtKB=Q5SVQ8 Q5SVQ8 ZBTB41 PTHR23226:SF330 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 41 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=22880|UniProtKB=Q96JG8 Q96JG8 MAGED4B PTHR11736:SF37 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN D4 scaffold/adaptor protein#PC00226 HUMAN|Ensembl=ENSG00000262748|UniProtKB=A0A140TA62 A0A140TA62 ENSG00000262748 PTHR23239:SF165 INTERMEDIATE FILAMENT IF ROD DOMAIN-CONTAINING PROTEIN-RELATED HUMAN|HGNC=25662|UniProtKB=Q6PD74 Q6PD74 AAGAB PTHR14659:SF1 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 HUMAN|HGNC=30722|UniProtKB=Q9BY14 Q9BY14 TEX101 PTHR16529:SF3 CD177 ANTIGEN TESTIS-EXPRESSED PROTEIN 101 regulation of microtubule-based process#GO:0032886;cell recognition#GO:0008037;fertilization#GO:0009566;regulation of locomotion#GO:0040012;microtubule-based movement#GO:0007018;regulation of localization#GO:0032879;sperm motility#GO:0097722;cilium movement involved in cell motility#GO:0060294;regulation of biological process#GO:0050789;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;sperm-egg recognition#GO:0035036;multi-organism reproductive process#GO:0044703;binding of sperm to zona pellucida#GO:0007339;regulation of cellular component movement#GO:0051270;regulation of cell motility#GO:2000145;single fertilization#GO:0007338;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;multi-organism process#GO:0051704;cell-cell recognition#GO:0009988;cilium movement#GO:0003341;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;reproduction#GO:0000003;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;locomotion#GO:0040011 plasma membrane raft#GO:0044853;anchored component of plasma membrane#GO:0046658;intrinsic component of membrane#GO:0031224;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;anchored component of membrane#GO:0031225;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;membrane region#GO:0098589;plasma membrane#GO:0005886;whole membrane#GO:0098805 HUMAN|HGNC=16859|UniProtKB=O75052 O75052 NOS1AP PTHR11232:SF17 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER CARBOXYL-TERMINAL PDZ LIGAND OF NEURONAL NITRIC OXIDE SYNTHASE PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18304|UniProtKB=Q14019 Q14019 COTL1 PTHR10829:SF29 CORTACTIN AND DREBRIN COACTOSIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;cortical cytoskeleton#GO:0030863;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;actin filament#GO:0005884;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 HUMAN|HGNC=17939|UniProtKB=Q9Y2W3 Q9Y2W3 SLC45A1 PTHR19432:SF6 SUGAR TRANSPORTER PROTON-ASSOCIATED SUGAR TRANSPORTER A solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;solute:cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=28116|UniProtKB=Q5TA50 Q5TA50 CPTP PTHR10219:SF20 GLYCOLIPID TRANSFER PROTEIN-RELATED CERAMIDE-1-PHOSPHATE TRANSFER PROTEIN binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 transfer/carrier protein#PC00219 HUMAN|HGNC=1169|UniProtKB=Q9NQ32 Q9NQ32 C11orf16 PTHR14343:SF3 VWFA DOMAIN-CONTAINING PROTEIN DUF4537 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=29956|UniProtKB=Q86UW2 Q86UW2 SLC51B PTHR36129:SF1 ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA transporter#PC00227 HUMAN|HGNC=24650|UniProtKB=Q9H9B1 Q9H9B1 EHMT1 PTHR46307:SF2 G9A, ISOFORM B HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1 HUMAN|HGNC=24329|UniProtKB=Q9Y3A2 Q9Y3A2 UTP11 PTHR12838:SF0 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=25974|UniProtKB=Q9HCC8 Q9HCC8 GDPD2 PTHR23344:SF1 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOINOSITOL INOSITOLPHOSPHODIESTERASE GDPD2 phosphodiesterase#PC00185 HUMAN|HGNC=24622|UniProtKB=Q8NFI3 Q8NFI3 ENGASE PTHR13246:SF1 ENDO BETA N-ACETYLGLUCOSAMINIDASE CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 deaminase#PC00088 HUMAN|HGNC=20438|UniProtKB=A8MTL3 A8MTL3 RNF212B PTHR22663:SF17 UNCHARACTERIZED RING FINGER PROTEIN 212B transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 homologous chromosome segregation#GO:0045143;macromolecule modification#GO:0043412;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;protein modification process#GO:0036211;telophase#GO:0051326;peptidyl-amino acid modification#GO:0018193;chromosome segregation#GO:0007059;M phase#GO:0000279;chromosome organization involved in meiotic cell cycle#GO:0070192;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle phase#GO:0022403;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear chromosome segregation#GO:0098813;meiosis I cell cycle phase#GO:0098764;peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;protein sumoylation#GO:0016925;homologous chromosome pairing at meiosis#GO:0007129;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=18287|UniProtKB=Q86XT2 Q86XT2 VPS37D PTHR13678:SF12 WILLIAMS-BEUREN SYNDROME CRITICAL REGION PROTEIN-RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37D protein catabolic process in the vacuole#GO:0007039;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;multivesicular body sorting pathway#GO:0071985;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;cellular protein catabolic process#GO:0044257;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=16102|UniProtKB=Q96KR6 Q96KR6 FAM210B PTHR21377:SF16 UNCHARACTERIZED PROTEIN FAM210B, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=10416|UniProtKB=P42677 P42677 RPS27 PTHR11594:SF1 40S RIBOSOMAL PROTEIN S27 40S RIBOSOMAL PROTEIN S27 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;ribonucleoprotein complex subunit organization#GO:0071826;ribonucleoprotein complex assembly#GO:0022618;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;ribosome biogenesis#GO:0042254;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=4327|UniProtKB=P23416 P23416 GLRA2 PTHR18945:SF28 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-2 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;transport#GO:0006810;system process#GO:0003008;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;regulation of biological process#GO:0050789;inorganic anion transmembrane transport#GO:0098661;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;signaling#GO:0023052;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=17686|UniProtKB=Q4ADV7 Q4ADV7 RIC1 PTHR22746:SF10 RAB6A-GEF COMPLEX PARTNER PROTEIN 1 GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1 Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=1374|UniProtKB=P07451 P07451 CA3 PTHR18952:SF127 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 3 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2085|UniProtKB=P04118 P04118 CLPS PTHR10041:SF8 COLIPASE COLIPASE response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;response to chemical#GO:0042221 protein-binding activity modulator#PC00095 HUMAN|HGNC=16223|UniProtKB=Q86VX2 Q86VX2 COMMD7 PTHR16231:SF2 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 7 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;tumor necrosis factor-mediated signaling pathway#GO:0033209;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to tumor necrosis factor#GO:0034612;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of DNA-binding transcription factor activity#GO:0043433;negative regulation of molecular function#GO:0044092 HUMAN|HGNC=6280|UniProtKB=O95279 O95279 KCNK5 PTHR11003:SF241 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 5 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=3466|UniProtKB=Q9NQ30 Q9NQ30 ESM1 PTHR15428:SF0 ENDOTHELIAL CELL-SPECIFIC MOLECULE 1 ESM-1 ENDOTHELIAL CELL-SPECIFIC MOLECULE 1 HUMAN|HGNC=14906|UniProtKB=Q8N4C6 Q8N4C6 NIN PTHR18905:SF11 NINEIN NINEIN cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cellular protein-containing complex assembly#GO:0034622;organelle localization#GO:0051640;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;microtubule anchoring#GO:0034453;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;protein polymerization#GO:0051258;centrosome localization#GO:0051642;cytoskeleton organization#GO:0007010;protein-containing complex subunit organization#GO:0043933 spindle pole#GO:0000922;microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;ciliary transition fiber#GO:0097539;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;spindle#GO:0005819;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 PDGF signaling pathway#P00047>GSK3#P01153 HUMAN|HGNC=26058|UniProtKB=Q14657 Q14657 LAGE3 PTHR31283:SF19 EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER EKC/KEOPS COMPLEX SUBUNIT LAGE3 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;tRNA threonylcarbamoyladenosine metabolic process#GO:0070525;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;EKC/KEOPS complex#GO:0000408;intracellular#GO:0005622 HUMAN|HGNC=6741|UniProtKB=Q9NQ48 Q9NQ48 LZTFL1 PTHR21635:SF0 LEUCINE ZIPPER TRANSCRIPTION FACTOR LIKE LEUCINE ZIPPER TRANSCRIPTION FACTOR-LIKE PROTEIN 1 cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;protein localization#GO:0008104;regulation of biological process#GO:0050789;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein localization to organelle#GO:0033365;negative regulation of cellular process#GO:0048523;regulation of protein localization#GO:0032880 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=28515|UniProtKB=Q96M61 Q96M61 MAGEB18 PTHR11736:SF23 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B18 scaffold/adaptor protein#PC00226 HUMAN|HGNC=27017|UniProtKB=Q3KRA6 Q3KRA6 C2orf76 PTHR18444:SF9 UPF0538 FAMILY MEMBER UPF0538 PROTEIN C2ORF76 HUMAN|HGNC=5183|UniProtKB=P25021 P25021 HRH2 PTHR24247:SF210 5-HYDROXYTRYPTAMINE RECEPTOR HISTAMINE H2 RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Histamine H2 receptor mediated signaling pathway#P04386>H2#P04489;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=28842|UniProtKB=Q9BQ04 Q9BQ04 RBM4B PTHR23147:SF80 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 4B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=17015|UniProtKB=Q13610 Q13610 PWP1 PTHR14091:SF0 PERIODIC TRYPTOPHAN PROTEIN 1 PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=53924|UniProtKB=P0DPK4 P0DPK4 NOTCH2NLC PTHR45836:SF15 SLIT HOMOLOG NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2-RELATED neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330;Notch signaling pathway#GO:0007219 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Notch signaling pathway#P00045>Notch#P01099;Angiogenesis#P00005>Notch#P00255;Notch signaling pathway#P00045>NIct#P01119;Alzheimer disease-presenilin pathway#P00004>Notch N-terminal fragment#P00171;Notch signaling pathway#P00045>NIcs#P01120;Notch signaling pathway#P00045>Ntm#P01114;Alzheimer disease-presenilin pathway#P00004>Notch C-terminal fragment#P00120;Notch signaling pathway#P00045>Next#P01103;Alzheimer disease-presenilin pathway#P00004>NICD#P00122;Alzheimer disease-presenilin pathway#P00004>Notch#P00176;Alzheimer disease-presenilin pathway#P00004>Notch fragment#P00154;Alzheimer disease-presenilin pathway#P00004>Notch transmembrane fragment#P00135;Alzheimer disease-presenilin pathway#P00004>Notch extracellular fragment#P00179 HUMAN|HGNC=30205|UniProtKB=Q9H7C9 Q9H7C9 AAMDC PTHR15811:SF5 MTH938 DOMAIN-CONTAINING PROTEIN MTH938 DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=1071|UniProtKB=P12644 P12644 BMP4 PTHR11848:SF165 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 4 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor serine/threonine kinase binding#GO:0033612 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;positive regulation of protein modification process#GO:0031401;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;negative regulation of cell death#GO:0060548;positive regulation of phosphate metabolic process#GO:0045937;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;positive regulation of response to stimulus#GO:0048584;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;cell death#GO:0008219;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of cellular protein metabolic process#GO:0032270;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817;TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=14197|UniProtKB=Q9H777 Q9H777 ELAC1 PTHR46018:SF2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 ZINC PHOSPHODIESTERASE ELAC PROTEIN 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;endoribonuclease activity#GO:0004521;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;ribonuclease activity#GO:0004540 phosphodiesterase#PC00185 HUMAN|HGNC=7697|UniProtKB=O95178 O95178 NDUFB2 PTHR15223:SF1 NADH-UBIQUINONE OXIDOREDUCTASE AGGG SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2, MITOCHONDRIAL envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=15449|UniProtKB=Q9UHV8 Q9UHV8 LGALS13 PTHR11346:SF120 GALECTIN GALACTOSIDE-BINDING SOLUBLE LECTIN 13-RELATED extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=11364|UniProtKB=P40763 P40763 STAT3 PTHR11801:SF2 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;defense response#GO:0006952;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;response to peptide hormone#GO:0043434;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;regulation of transcription, DNA-templated#GO:0006355;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;organic cyclic compound biosynthetic process#GO:1901362;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>STAT#P01173;Angiogenesis#P00005>STAT3#P00217;CCKR signaling map#P06959>STAT3#P07165;JAK/STAT signaling pathway#P00038>STAT#P01027;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832;Gonadotropin-releasing hormone receptor pathway#P06664>STAT3#P06795;Ras Pathway#P04393>Stat 1/3#P04566;Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561 HUMAN|HGNC=26013|UniProtKB=Q86Y56 Q86Y56 DNAAF5 PTHR16216:SF2 DYNEIN ASSEMBLY FACTOR 5, AXONEMAL DYNEIN ASSEMBLY FACTOR 5, AXONEMAL chaperone#PC00072 HUMAN|HGNC=6395|UniProtKB=P52292 P52292 KPNA2 PTHR23316:SF12 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-1 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=28318|UniProtKB=A6PVS8 A6PVS8 LRRIQ3 PTHR46723:SF1 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=16497|UniProtKB=Q9NRQ2 Q9NRQ2 PLSCR4 PTHR23248:SF28 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE 4 phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;plasma membrane organization#GO:0007009;ion transport#GO:0006811;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=9668|UniProtKB=P23468 P23468 PTPRD PTHR19134:SF430 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE DELTA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=20293|UniProtKB=Q7L211 Q7L211 ABHD13 PTHR12277:SF81 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD13 serine protease#PC00203 HUMAN|HGNC=23393|UniProtKB=Q86X55 Q86X55 CARM1 PTHR11006:SF51 PROTEIN ARGININE N-METHYLTRANSFERASE HISTONE-ARGININE METHYLTRANSFERASE CARM1 protein modifying enzyme#PC00260 HUMAN|HGNC=29088|UniProtKB=Q29RF7 Q29RF7 PDS5A PTHR12663:SF2 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED SISTER CHROMATID COHESION PROTEIN PDS5 HOMOLOG A DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;sister chromatid cohesion#GO:0007062;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;nuclear chromosome segregation#GO:0098813;mitotic sister chromatid cohesion#GO:0007064;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;organelle fission#GO:0048285;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=14872|UniProtKB=Q9BXN1 Q9BXN1 ASPN PTHR45712:SF2 AGAP008170-PA ASPORIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=33886|UniProtKB=P0CL84 P0CL84 STAG3L2 PTHR11199:SF8 STROMAL ANTIGEN COHESIN SUBUNIT SA-3-RELATED binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;chromatin#GO:0000785;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=25769|UniProtKB=Q8N9T8 Q8N9T8 KRI1 PTHR14490:SF5 ZINC FINGER, ZZ TYPE PROTEIN KRI1 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;cleavage involved in rRNA processing#GO:0000469;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;endonucleolytic cleavage involved in rRNA processing#GO:0000478;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 HUMAN|HGNC=17732|UniProtKB=Q9UMS6 Q9UMS6 SYNPO2 PTHR24217:SF9 PUTATIVE-RELATED SYNAPTOPODIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;positive regulation of cytoskeleton organization#GO:0051495;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;actin cytoskeleton organization#GO:0030036;positive regulation of biological process#GO:0048518 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=37240|UniProtKB=Q8TC17 Q8TC17 GRAPL PTHR19969:SF18 SH2-SH3 ADAPTOR PROTEIN-RELATED GRB2-RELATED ADAPTER PROTEIN-LIKE scaffold/adaptor protein#PC00226 HUMAN|HGNC=44450|UniProtKB=D6RA61 D6RA61 USP17L22 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=8600|UniProtKB=Q96RD6 Q96RD6 PANX2 PTHR15759:SF7 PANNEXIN PANNEXIN-2 HUMAN|HGNC=22206|UniProtKB=Q8NCT3 Q8NCT3 KIAA0895 PTHR31817:SF3 FAMILY NOT NAMED SI:DKEY-222B8.4 HUMAN|HGNC=1142|UniProtKB=Q9UIR0 Q9UIR0 BTNL2 PTHR24100:SF105 BUTYROPHILIN BTNL2-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=17613|UniProtKB=Q9NZS9 Q9NZS9 BFAR PTHR15898:SF1 UNCHARACTERIZED BIFUNCTIONAL APOPTOSIS REGULATOR ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25653|UniProtKB=Q5JVF3 Q5JVF3 PCID2 PTHR12732:SF0 UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING PCI DOMAIN-CONTAINING PROTEIN 2 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;cellular localization#GO:0051641;heterocycle catabolic process#GO:0046700;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule catabolic process#GO:0009057;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;nuclear export#GO:0051168;chromosome organization#GO:0051276;protein transport#GO:0015031;aromatic compound biosynthetic process#GO:0019438;intracellular transport#GO:0046907;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;protein-containing complex localization#GO:0031503;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nucleic acid transport#GO:0050657;biosynthetic process#GO:0009058;ribonucleoprotein complex export from nucleus#GO:0071426;cellular nitrogen compound catabolic process#GO:0044270;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;organic cyclic compound metabolic process#GO:1901360;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;mRNA catabolic process#GO:0006402;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;protein export from nucleus#GO:0006611;RNA catabolic process#GO:0006401;DNA-templated transcription, elongation#GO:0006354;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleic acid-templated transcription#GO:0097659;mRNA export from nucleus#GO:0006406;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;intracellular mRNA localization#GO:0008298;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;ribonucleoprotein complex localization#GO:0071166;organic cyclic compound biosynthetic process#GO:1901362;mRNA transport#GO:0051028;cellular process#GO:0009987;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;nucleocytoplasmic transport#GO:0006913;negative regulation of macromolecule metabolic process#GO:0010605;nucleobase-containing compound transport#GO:0015931;transcription elongation from RNA polymerase II promoter#GO:0006368;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;RNA export from nucleus#GO:0006405;cellular macromolecule catabolic process#GO:0044265;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=13198|UniProtKB=P98168 P98168 ZXDA PTHR46179:SF18 ZINC FINGER PROTEIN ZINC FINGER X-LINKED PROTEIN ZXDA transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=5008|UniProtKB=P54868 P54868 HMGCS2 PTHR43323:SF1 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE HYDROXYMETHYLGLUTARYL-COA SYNTHASE, MITOCHONDRIAL transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=32671|UniProtKB=Q6ZMU5 Q6ZMU5 TRIM72 PTHR24103:SF11 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 72 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=16882|UniProtKB=Q9Y3Q4 Q9Y3Q4 HCN4 PTHR45689:SF4 I[[H]] CHANNEL, ISOFORM E POTASSIUM/SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 4 ion channel#PC00133 HUMAN|HGNC=25228|UniProtKB=Q96HU1 Q96HU1 SGSM3 PTHR22957:SF296 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 3 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=30459|UniProtKB=Q8N9I5 Q8N9I5 FADS6 PTHR19353:SF13 FATTY ACID DESATURASE 2 FATTY ACID DESATURASE 6 HUMAN|HGNC=21036|UniProtKB=Q9NWS9 Q9NWS9 ZNF446 PTHR23226:SF210 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 446 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=201|UniProtKB=Q9P0K1 Q9P0K1 ADAM22 PTHR11905:SF14 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 22 intrinsic component of postsynaptic membrane#GO:0098936;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;integral component of synaptic membrane#GO:0099699;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;synaptic membrane#GO:0097060;integral component of postsynaptic specialization membrane#GO:0099060;integral component of postsynaptic membrane#GO:0099055;asymmetric synapse#GO:0032279;intrinsic component of membrane#GO:0031224;intrinsic component of synaptic membrane#GO:0099240;integral component of postsynaptic density membrane#GO:0099061;postsynaptic density membrane#GO:0098839;integral component of plasma membrane#GO:0005887;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;intrinsic component of postsynaptic specialization membrane#GO:0098948;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=15873|UniProtKB=Q9GZN8 Q9GZN8 C20orf27 PTHR13287:SF6 UNCHARACTERIZED UPF0687 PROTEIN C20ORF27 HUMAN|HGNC=11281|UniProtKB=Q9HD15 Q9HD15 SRA1 PTHR18834:SF2 STEROID RECEPTOR RNA ACTIVATOR 1 STEROID RECEPTOR RNA ACTIVATOR 1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110;nuclear receptor transcription coactivator activity#GO:0030374 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=38603|UniProtKB=P0C874 P0C874 SPATA31D3 PTHR21859:SF50 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31D3-RELATED HUMAN|HGNC=9302|UniProtKB=P30153 P30153 PPP2R1A PTHR10648:SF2 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 65 KDA REGULATORY SUBUNIT A ALPHA ISOFORM phosphatase binding#GO:0019902;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;protein serine/threonine phosphatase activity#GO:0004722;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 HUMAN|HGNC=5972|UniProtKB=Q99665 Q99665 IL12RB2 PTHR23036:SF79 CYTOKINE RECEPTOR INTERLEUKIN-12 RECEPTOR SUBUNIT BETA-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 HUMAN|HGNC=24667|UniProtKB=Q8TD08 Q8TD08 MAPK15 PTHR24055:SF79 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 15 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>ERK1-2#P00543;Interleukin signaling pathway#P00036>ERK#P00965;PDGF signaling pathway#P00047>ERK#P01143;Parkinson disease#P00049>ERK#P01211;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099 HUMAN|HGNC=40|UniProtKB=P08183 P08183 ABCB1 PTHR24221:SF251 ATP-BINDING CASSETTE SUB-FAMILY B ATP-DEPENDENT TRANSLOCASE ABCB1 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=29545|UniProtKB=Q9H7L9 Q9H7L9 SUDS3 PTHR21964:SF13 BREAST CANCER METASTASIS-SUPPRESSOR 1 SIN3 HISTONE DEACETYLASE COREPRESSOR COMPLEX COMPONENT SDS3 HUMAN|HGNC=7224|UniProtKB=P39210 P39210 MPV17 PTHR11266:SF17 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 PROTEIN MPV17 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transporter#PC00227 HUMAN|HGNC=2520|UniProtKB=Q9NRF8 Q9NRF8 CTPS2 PTHR11550:SF2 CTP SYNTHASE CTP SYNTHASE 2 identical protein binding#GO:0042802;ligase activity#GO:0016874;protein binding#GO:0005515;binding#GO:0005488;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;pyrimidine nucleobase metabolic process#GO:0006206;pyrimidine nucleotide biosynthetic process#GO:0006221;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 De novo pyrimidine ribonucleotides biosythesis#P02740>CTP synthase#P02931 HUMAN|HGNC=12287|UniProtKB=A0A075B6R0 A0A075B6R0 TRGV2 PTHR19256:SF57 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 2-RELATED HUMAN|HGNC=26984|UniProtKB=Q4VC39 Q4VC39 HIGD2B PTHR12297:SF8 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 2B-RELATED cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=24050|UniProtKB=Q8IUR6 Q8IUR6 CREBRF PTHR21552:SF2 ADULT RETINA PROTEIN CREB3 REGULATORY FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19354|UniProtKB=O75182 O75182 SIN3B PTHR12346:SF1 SIN3B-RELATED PAIRED AMPHIPATHIC HELIX PROTEIN SIN3B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;molecular function regulator#GO:0098772;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>Sin3A#P00771 HUMAN|HGNC=19073|UniProtKB=Q8NI27 Q8NI27 THOC2 PTHR21597:SF0 THO2 PROTEIN THO COMPLEX SUBUNIT 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 HUMAN|HGNC=30052|UniProtKB=Q8TEM1 Q8TEM1 NUP210 PTHR23019:SF2 NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=24361|UniProtKB=A8K0Z3 A8K0Z3 WASHC1 PTHR23331:SF2 CXYORF1 WAS PROTEIN FAMILY HOMOLOG 2-RELATED HUMAN|HGNC=14533|UniProtKB=P0CB47 P0CB47 UBTFL1 PTHR46318:SF1 UPSTREAM BINDING TRANSCRIPTION FACTOR UPSTREAM-BINDING FACTOR 1-LIKE PROTEIN 1-RELATED DNA-binding transcription factor#PC00218 HUMAN|HGNC=2578|UniProtKB=P04839 P04839 CYBB PTHR11972:SF60 NADPH OXIDASE CYTOCHROME B-245 HEAVY CHAIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;oxidoreductase complex#GO:1990204;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175 HUMAN|HGNC=462|UniProtKB=Q99218 Q99218 AMELY PTHR46794:SF4 AMELOGENIN, Y ISOFORM AMELOGENIN, Y ISOFORM HUMAN|HGNC=18629|UniProtKB=Q8WWQ8 Q8WWQ8 STAB2 PTHR24038:SF0 STABILIN STABILIN-2 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=9021|UniProtKB=P14618 P14618 PKM PTHR11817:SF15 PYRUVATE KINASE PYRUVATE KINASE PKM carbon-oxygen lyase activity#GO:0016835;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydro-lyase activity#GO:0016836;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;lyase activity#GO:0016829;isomerase activity#GO:0016853;oxidoreductase activity#GO:0016491;kinase activity#GO:0016301 purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;cellular response to hormone stimulus#GO:0032870;ATP metabolic process#GO:0046034;ATP generation from ADP#GO:0006757;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;oxoacid metabolic process#GO:0043436;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;cellular response to organonitrogen compound#GO:0071417;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;ADP metabolic process#GO:0046031;organonitrogen compound metabolic process#GO:1901564;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132;Glycolysis#P00024>Pyruvate kinase#P00675 HUMAN|HGNC=1140|UniProtKB=O00478 O00478 BTN3A3 PTHR24100:SF56 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 3 MEMBER A3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=10060|UniProtKB=Q9BXT8 Q9BXT8 RNF17 PTHR16442:SF1 RING FINGER PROTEIN 17 RING FINGER PROTEIN 17 HUMAN|HGNC=25015|UniProtKB=Q9BTX3 Q9BTX3 TMEM208 PTHR13505:SF7 TRANSMEMBRANE PROTEIN 208 TRANSMEMBRANE PROTEIN 208 macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;vacuolar protein processing#GO:0006624;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=15673|UniProtKB=Q8WWQ0 Q8WWQ0 PHIP PTHR16266:SF4 WD REPEAT DOMAIN 9 PH-INTERACTING PROTEIN cellular aromatic compound metabolic process#GO:0006725;regulation of anatomical structure morphogenesis#GO:0022603;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;regulation of cell shape#GO:0008360;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;cytoskeleton organization#GO:0007010;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10588|UniProtKB=Q99250 Q99250 SCN2A PTHR10037:SF278 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 2 SUBUNIT ALPHA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sodium channel activity#GO:0005272;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;sodium ion transport#GO:0006814;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=29958|UniProtKB=Q8NEX9 Q8NEX9 SDR9C7 PTHR43313:SF5 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C MEMBER 7 dehydrogenase#PC00092 HUMAN|HGNC=23519|UniProtKB=Q96D05 Q96D05 FAM241B PTHR33690:SF2 DUF4605 DOMAIN-CONTAINING PROTEIN PROTEIN FAM241B membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=23112|UniProtKB=Q8TDW7 Q8TDW7 FAT3 PTHR24026:SF49 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN FAT 3 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=3035|UniProtKB=Q08554 Q08554 DSC1 PTHR24025:SF8 DESMOGLEIN FAMILY MEMBER DESMOCOLLIN-1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cadherin#PC00057 HUMAN|HGNC=34415|UniProtKB=A6NC51 A6NC51 TMEM150B PTHR21324:SF3 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED MODULATOR OF MACROAUTOPHAGY TMEM150B process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;biological regulation#GO:0065007;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;cellular catabolic process#GO:0044248;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6292|UniProtKB=Q9UGI6 Q9UGI6 KCNN3 PTHR10153:SF40 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;calmodulin binding#GO:0005516;transporter activity#GO:0005215;channel activity#GO:0015267;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=25193|UniProtKB=Q6ZWT7 Q6ZWT7 MBOAT2 PTHR13906:SF7 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 2 transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;membrane#GO:0016020 acetyltransferase#PC00038 HUMAN|HGNC=5975|UniProtKB=Q14627 Q14627 IL13RA2 PTHR23036:SF101 CYTOKINE RECEPTOR INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=8467|UniProtKB=Q8NG95 Q8NG95 OR7G3 PTHR48001:SF123 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7G3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|Gene=HPF1L_HUMAN|UniProtKB=A8MVJ9 A8MVJ9 - PTHR13386:SF3 HISTONE PARYLATION FACTOR 1 HISTONE PARYLATION FACTOR 1-LIKE-RELATED cation binding#GO:0043169;carbohydrate derivative binding#GO:0097367;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;histone binding#GO:0042393 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=8174|UniProtKB=O60404 O60404 OR10H3 PTHR24247:SF128 5-HYDROXYTRYPTAMINE RECEPTOR OLFACTORY RECEPTOR 10H3 cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=37101|UniProtKB=A8MPP1 A8MPP1 DDX11L8 PTHR11472:SF41 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER ATP-DEPENDENT DNA HELICASE DDX11-RELATED pyrophosphatase activity#GO:0016462;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;DNA conformation change#GO:0071103;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA duplex unwinding#GO:0032508;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059;DNA geometric change#GO:0032392 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA helicase#PC00011 HUMAN|HGNC=25889|UniProtKB=Q17RM4 Q17RM4 CCDC142 PTHR21436:SF2 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 142 HUMAN|HGNC=17886|UniProtKB=O75526 O75526 RBMXL2 PTHR13952:SF11 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD RNA-BINDING MOTIF PROTEIN, X-LINKED-LIKE-2-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U12-type spliceosomal complex#GO:0005689 RNA splicing factor#PC00148 HUMAN|HGNC=24592|UniProtKB=Q658P3 Q658P3 STEAP3 PTHR14239:SF8 DUDULIN-RELATED METALLOREDUCTASE STEAP3 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;iron ion transmembrane transport#GO:0034755;localization#GO:0051179;establishment of localization#GO:0051234;oxidation-reduction process#GO:0055114;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;metabolic process#GO:0008152 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=4834|UniProtKB=Q9Y450 Q9Y450 HBS1L PTHR23115:SF188 TRANSLATION FACTOR HBS1-LIKE PROTEIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular macromolecule biosynthetic process#GO:0034645;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation factor#PC00223 HUMAN|HGNC=4515|UniProtKB=P46095 P46095 GPR6 PTHR22750:SF19 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=6232|UniProtKB=Q92953 Q92953 KCNB2 PTHR11537:SF134 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=14707|UniProtKB=Q8NGC5 Q8NGC5 OR6J1 PTHR26454:SF53 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6J1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=11850|UniProtKB=O00206 O00206 TLR4 PTHR24365:SF521 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 4 carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;binding#GO:0005488 response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;interspecies interaction between organisms#GO:0044419;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;pattern recognition receptor signaling pathway#GO:0002221;cellular process#GO:0009987;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;defense response to bacterium#GO:0042742;defense response to Gram-negative bacterium#GO:0050829;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response#GO:0006952;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Toll receptor signaling pathway#P00054>TLR4#P01339;Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR#P01346 HUMAN|HGNC=8776|UniProtKB=Q14123 Q14123 PDE1C PTHR11347:SF32 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CALCIUM/CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1C hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 HUMAN|HGNC=28286|UniProtKB=Q08AF3 Q08AF3 SLFN5 PTHR12155:SF26 SCHLAFEN SCHLAFEN FAMILY MEMBER 5 HUMAN|HGNC=24030|UniProtKB=A9UHW6 A9UHW6 MIF4GD PTHR23254:SF17 EIF4G DOMAIN PROTEIN MIF4G DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;regulation of translational initiation#GO:0006446;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;translational initiation#GO:0006413;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=26722|UniProtKB=Q8N9M5 Q8N9M5 TMEM102 PTHR10656:SF48 CELL FATE DETERMINING PROTEIN MAB21-RELATED TRANSMEMBRANE PROTEIN 102 HUMAN|HGNC=2192|UniProtKB=P39059 P39059 COL15A1 PTHR24023:SF912 COLLAGEN ALPHA COLLAGEN ALPHA-1(XV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=9438|UniProtKB=O75569 O75569 PRKRA PTHR46205:SF2 LOQUACIOUS, ISOFORM B INTERFERON-INDUCIBLE DOUBLE-STRANDED RNA-DEPENDENT PROTEIN KINASE ACTIVATOR A Apoptosis signaling pathway#P00006>PACT#P00280 HUMAN|HGNC=6236|UniProtKB=Q03721 Q03721 KCNC4 PTHR11537:SF126 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;cell leading edge#GO:0031252;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;cell body#GO:0044297;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=26034|UniProtKB=Q9NX18 Q9NX18 SDHAF2 PTHR12469:SF2 PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular component biogenesis#GO:0044085;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;tricarboxylic acid cycle#GO:0006099;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;mitochondrial respiratory chain complex assembly#GO:0033108;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein-containing complex assembly#GO:0065003;protein modification process#GO:0036211;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;mitochondrial respiratory chain complex II assembly#GO:0034553;organelle organization#GO:0006996;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=32008|UniProtKB=A0PK00 A0PK00 TMEM120B PTHR21433:SF2 TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA TRANSMEMBRANE PROTEIN 120B cellular developmental process#GO:0048869;cell differentiation#GO:0030154;fat cell differentiation#GO:0045444;cellular process#GO:0009987;developmental process#GO:0032502 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=8108|UniProtKB=Q01968 Q01968 OCRL PTHR11200:SF176 INOSITOL 5-PHOSPHATASE INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;small molecule catabolic process#GO:0044282;glycerolipid metabolic process#GO:0046486;cellular carbohydrate metabolic process#GO:0044262;dephosphorylation#GO:0016311;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=7939|UniProtKB=P01160 P01160 NPPA PTHR14066:SF2 ATRIAL NATRIURETIC FACTOR PRECURSOR NATRIURETIC PEPTIDES A receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;molecular function regulator#GO:0098772;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427 cyclic nucleotide metabolic process#GO:0009187;system process#GO:0003008;purine nucleotide biosynthetic process#GO:0006164;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;enzyme linked receptor protein signaling pathway#GO:0007167;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;circulatory system process#GO:0003013;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;blood circulation#GO:0008015;signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;second-messenger-mediated signaling#GO:0019932;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;neuropeptide signaling pathway#GO:0007218;cellular nitrogen compound biosynthetic process#GO:0044271;signaling#GO:0023052;metabolic process#GO:0008152;negative regulation of blood pressure#GO:0045776;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;regulation of systemic arterial blood pressure#GO:0003073;cellular biosynthetic process#GO:0044249;cGMP-mediated signaling#GO:0019934;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of blood pressure#GO:0008217;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;nucleobase-containing small molecule metabolic process#GO:0055086;cyclic-nucleotide-mediated signaling#GO:0019935;purine ribonucleotide biosynthetic process#GO:0009152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=611|UniProtKB=P55056 P55056 APOC4 PTHR32288:SF0 APOLIPOPROTEIN C-IV APOLIPOPROTEIN C-IV localization#GO:0051179;regulation of biological process#GO:0050789;triglyceride homeostasis#GO:0070328;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;maintenance of location#GO:0051235;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;regulation of localization#GO:0032879;lipid localization#GO:0010876;lipid storage#GO:0019915;chemical homeostasis#GO:0048878;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;high-density lipoprotein particle#GO:0034364;extracellular region#GO:0005576 apolipoprotein#PC00052 HUMAN|HGNC=24824|UniProtKB=Q9UM11 Q9UM11 FZR1 PTHR19918:SF1 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;regulation of cellular protein catabolic process#GO:1903362;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=32670|UniProtKB=Q309B1 Q309B1 TRIM16L PTHR25465:SF10 FAMILY NOT NAMED TRIPARTITE MOTIF-CONTAINING PROTEIN 16-RELATED HUMAN|HGNC=29585|UniProtKB=Q8N6V9 Q8N6V9 TEX9 PTHR23313:SF0 TSEC1-RELATED TESTIS-EXPRESSED PROTEIN 9 actin binding motor protein#PC00040 HUMAN|HGNC=27614|UniProtKB=Q0D2J5 Q0D2J5 ZNF763 PTHR24390:SF140 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 763 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23200|UniProtKB=O60381 O60381 HBP1 PTHR15499:SF3 HMG BOX-CONTAINING PROTEIN 1 HMG BOX-CONTAINING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=5588|UniProtKB=P01764 P01764 IGHV3-23 PTHR23266:SF339 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-23-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=24328|UniProtKB=Q9Y221 Q9Y221 NIP7 PTHR23415:SF34 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 HOMOLOG cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 scaffold/adaptor protein#PC00226 HUMAN|HGNC=42967|UniProtKB=A6NEH6 A6NEH6 TMEM247 PTHR36691:SF1 TRANSMEMBRANE PROTEIN 247 TRANSMEMBRANE PROTEIN 247 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=8692|UniProtKB=Q9Y5E2 Q9Y5E2 PCDHB7 PTHR24028:SF69 CADHERIN-87A PROTOCADHERIN BETA-7 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=30923|UniProtKB=Q8TF74 Q8TF74 WIPF2 PTHR23202:SF3 WASP INTERACTING PROTEIN-RELATED WAS/WASL-INTERACTING PROTEIN FAMILY MEMBER 2 movement of cell or subcellular component#GO:0006928;actin filament-based process#GO:0030029;cellular process#GO:0009987 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=30552|UniProtKB=Q6ZMN7 Q6ZMN7 PDZRN4 PTHR15545:SF6 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 PDZ DOMAIN-CONTAINING RING FINGER PROTEIN 4 HUMAN|HGNC=18610|UniProtKB=Q6VAB6 Q6VAB6 KSR2 PTHR23257:SF775 SERINE-THREONINE PROTEIN KINASE KINASE SUPPRESSOR OF RAS 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=4964|UniProtKB=P17693 P17693 HLA-G PTHR16675:SF169 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN G protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;amide binding#GO:0033218;peptide binding#GO:0042277 immune response#GO:0006955;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;T cell mediated immunity#GO:0002456;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=28301|UniProtKB=Q6PKX4 Q6PKX4 DOK6 PTHR21258:SF43 DOCKING PROTEIN RELATED DOCKING PROTEIN 6 HUMAN|HGNC=1436|UniProtKB=P29377 P29377 S100G PTHR11639:SF73 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-G protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=4935|UniProtKB=P28068 P28068 HLA-DMB PTHR19944:SF65 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DM BETA CHAIN major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 HUMAN|HGNC=16018|UniProtKB=Q86UW7 Q86UW7 CADPS2 PTHR12166:SF7 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR 2 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;positive regulation of exocytosis#GO:0045921;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;positive regulation of biological process#GO:0048518;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;positive regulation of secretion#GO:0051047;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;export from cell#GO:0140352 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical entity#GO:0110165 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=2325|UniProtKB=Q9P2I0 Q9P2I0 CPSF2 PTHR45922:SF1 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 HUMAN|HGNC=1549|UniProtKB=O75828 O75828 CBR3 PTHR43963:SF3 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE [NADPH] 3 reductase#PC00198 HUMAN|HGNC=6868|UniProtKB=Q96JE9 Q96JE9 MAP6 PTHR14759:SF29 STOP PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 6 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;regulation of organelle organization#GO:0033043;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cytoskeleton-dependent intracellular transport#GO:0030705;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;microtubule cytoskeleton#GO:0015630;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=21718|UniProtKB=Q96CH1 Q96CH1 GPR146 PTHR24226:SF3 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 G-PROTEIN COUPLED RECEPTOR 146-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=27729|UniProtKB=Q495C1 Q495C1 RNF212 PTHR22663:SF21 UNCHARACTERIZED E3 SUMO-PROTEIN LIGASE RNF212-RELATED transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 homologous chromosome segregation#GO:0045143;macromolecule modification#GO:0043412;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;protein modification process#GO:0036211;telophase#GO:0051326;peptidyl-amino acid modification#GO:0018193;chromosome segregation#GO:0007059;M phase#GO:0000279;chromosome organization involved in meiotic cell cycle#GO:0070192;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle phase#GO:0022403;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear chromosome segregation#GO:0098813;meiosis I cell cycle phase#GO:0098764;peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;protein sumoylation#GO:0016925;homologous chromosome pairing at meiosis#GO:0007129;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=28743|UniProtKB=Q86UF1 Q86UF1 TSPAN33 PTHR19282:SF154 TETRASPANIN TETRASPANIN-33 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=4170|UniProtKB=P15976 P15976 GATA1 PTHR10071:SF190 TRANSCRIPTION FACTOR GATA FAMILY MEMBER ERYTHROID TRANSCRIPTION FACTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=25899|UniProtKB=Q96T17 Q96T17 MAP7D2 PTHR15073:SF3 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 2 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=24436|UniProtKB=Q8WYK0 Q8WYK0 ACOT12 PTHR11049:SF3 ACYL COENZYME A THIOESTER HYDROLASE ACETYL-COENZYME A THIOESTERASE hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;thiolester hydrolase activity#GO:0016790;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982 esterase#PC00097 HUMAN|HGNC=1590|UniProtKB=O96020 O96020 CCNE2 PTHR10177:SF70 CYCLINS G1/S-SPECIFIC CYCLIN-E2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;G1/S transition of mitotic cell cycle#GO:0000082;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 Parkinson disease#P00049>Cyclin E#P01213;Cell cycle#P00013>CdkC#P00489 HUMAN|HGNC=39026|UniProtKB=Q9WJR5 Q9WJR5 ERVK-19 PTHR41694:SF4 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 10 POL PROTEIN-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 viral or transposable element protein#PC00237 HUMAN|HGNC=22952|UniProtKB=Q8N2C3 Q8N2C3 DEPDC4 PTHR16206:SF10 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 4 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20502|UniProtKB=Q6ZMH5 Q6ZMH5 SLC39A5 PTHR12191:SF17 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP5 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;divalent inorganic cation homeostasis#GO:0072507;response to growth factor#GO:0070848;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;divalent metal ion transport#GO:0070838;response to endogenous stimulus#GO:0009719;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;response to BMP#GO:0071772;transition metal ion transport#GO:0000041;signaling#GO:0023052;response to organic substance#GO:0010033;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;cellular response to endogenous stimulus#GO:0071495;transmembrane transport#GO:0055085;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;BMP signaling pathway#GO:0030509;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=9198|UniProtKB=P53803 P53803 POLR2K PTHR12056:SF2 DNA-DIRECTED RNA POLYMERASES I, II, AND III DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;RNA polymerase II, holoenzyme#GO:0016591;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736 DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 HUMAN|HGNC=20208|UniProtKB=Q96HA9 Q96HA9 PEX11G PTHR20990:SF1 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11C HUMAN|HGNC=103|UniProtKB=Q9H8M5 Q9H8M5 CNNM2 PTHR12064:SF22 ANCIENT CONSERVED DOMAIN PROTEIN-RELATED METAL TRANSPORTER CNNM2 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;transport#GO:0006810;biological regulation#GO:0065007;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;metal ion homeostasis#GO:0055065 intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=16791|UniProtKB=Q8WW01 Q8WW01 TSEN15 PTHR28582:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15 HUMAN|HGNC=33755|UniProtKB=Q6ZW13 Q6ZW13 C16orf86 PTHR37867:SF1 CHROMOSOME 16 OPEN READING FRAME 86 CHROMOSOME 3 C16ORF86 HOMOLOG HUMAN|HGNC=24168|UniProtKB=Q6WN34 Q6WN34 CHRDL2 PTHR46303:SF3 VWFC DOMAIN-CONTAINING PROTEIN CHORDIN-LIKE PROTEIN 2 HUMAN|HGNC=19766|UniProtKB=A6NK59 A6NK59 ASB14 PTHR24121:SF10 NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED ANKYRIN REPEAT AND SOCS BOX PROTEIN 14 HUMAN|HGNC=12193|UniProtKB=A0A087X0M5 A0A087X0M5 TRBV18 PTHR23268:SF88 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 18 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=15033|UniProtKB=Q8NGW6 Q8NGW6 OR6K6 PTHR26451:SF132 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 6K6 HUMAN|HGNC=30713|UniProtKB=Q96M93 Q96M93 ADAD1 PTHR10910:SF103 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;double-stranded RNA binding#GO:0003725 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=11725|UniProtKB=Q9UIF3 Q9UIF3 TEKT2 PTHR19960:SF7 TEKTIN TEKTIN-2 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cilium movement involved in cell motility#GO:0060294;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=16837|UniProtKB=O95711 O95711 LY86 PTHR20838:SF0 LYMPHOCYTE ANTIGEN 86 LYMPHOCYTE ANTIGEN 86 HUMAN|HGNC=17574|UniProtKB=Q96L96 Q96L96 ALPK3 PTHR47091:SF1 ALPHA-PROTEIN KINASE 2-RELATED ALPHA-PROTEIN KINASE 3 cellular developmental process#GO:0048869;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;cellular process#GO:0009987;tissue development#GO:0009888;cardiac muscle cell development#GO:0055013;muscle tissue development#GO:0060537;muscle cell development#GO:0055001;cell development#GO:0048468;muscle structure development#GO:0061061;system development#GO:0048731;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;cardiocyte differentiation#GO:0035051;striated muscle cell development#GO:0055002;multicellular organismal process#GO:0032501 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=4953|UniProtKB=Q30154 Q30154 HLA-DRB5 PTHR19944:SF97 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR BETA 5 CHAIN major histocompatibility complex protein#PC00149 HUMAN|HGNC=9069|UniProtKB=Q15149 Q15149 PLEC PTHR23169:SF20 ENVOPLAKIN PLECTIN cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cell-substrate junction assembly#GO:0007044;cellular component assembly#GO:0022607;response to stimulus#GO:0050896;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;response to wounding#GO:0009611;organelle organization#GO:0006996;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;cytoskeleton organization#GO:0007010;wound healing#GO:0042060;cellular component organization#GO:0016043;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104 supramolecular complex#GO:0099080;perinuclear region of cytoplasm#GO:0048471;intermediate filament#GO:0005882;anchoring junction#GO:0070161;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130 HUMAN|HGNC=30307|UniProtKB=O00124 O00124 UBXN8 PTHR23322:SF21 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 8 HUMAN|HGNC=23272|UniProtKB=Q5CZA5 Q5CZA5 ZNF805 PTHR24377:SF710 IP01015P-RELATED ZINC FINGER PROTEIN 805 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18371|UniProtKB=Q9BQT9 Q9BQT9 CLSTN3 PTHR14139:SF5 CALSYNTENIN CALSYNTENIN-3 cellular component biogenesis#GO:0044085;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;positive regulation of multicellular organismal process#GO:0051240 cell surface#GO:0009986;synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=19108|UniProtKB=P59542 P59542 TAS2R19 PTHR11394:SF139 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 19-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=37181|UniProtKB=P0C7I0 P0C7I0 USP17L8 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=13633|UniProtKB=Q15848 Q15848 ADIPOQ PTHR15427:SF20 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER ADIPONECTIN Gonadotropin-releasing hormone receptor pathway#P06664>Adiponectin#P06761 HUMAN|HGNC=30852|UniProtKB=Q16560 Q16560 SNRNP35 PTHR13952:SF23 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 35 KDA PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U12-type spliceosomal complex#GO:0005689 RNA splicing factor#PC00148 HUMAN|HGNC=1707|UniProtKB=P10966 P10966 CD8B PTHR11292:SF7 T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN-RELATED cell surface#GO:0009986;cellular anatomical entity#GO:0110165 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=31271|UniProtKB=A6NHA9 A6NHA9 OR4C46 PTHR48002:SF98 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C46 transmembrane signal receptor#PC00197 HUMAN|HGNC=11391|UniProtKB=Q9UQB9 Q9UQB9 AURKC PTHR24350:SF3 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cell division#GO:0051301;mitotic spindle organization#GO:0007052;membrane fission#GO:0090148;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;regulation of cell division#GO:0051302;mitotic cell cycle process#GO:1903047;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;spindle organization#GO:0007051;cytokinesis#GO:0000910;regulation of cytokinesis#GO:0032465 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome#GO:0000794;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;centrosome#GO:0005813;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;spindle#GO:0005819;microtubule#GO:0005874;membrane-enclosed lumen#GO:0031974;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;organelle lumen#GO:0043233;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome, centromeric region#GO:0000780;supramolecular fiber#GO:0099512;centriole#GO:0005814;polymeric cytoskeletal fiber#GO:0099513;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=11370|UniProtKB=O95793 O95793 STAU1 PTHR46054:SF2 MATERNAL EFFECT PROTEIN STAUFEN DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 1 HUMAN|HGNC=21597|UniProtKB=Q6JQN1 Q6JQN1 ACAD10 PTHR48083:SF13 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE FAMILY MEMBER 10-RELATED dehydrogenase#PC00092 HUMAN|HGNC=926|UniProtKB=O60512 O60512 B4GALT3 PTHR19300:SF33 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 3 glycosyltransferase#PC00111 HUMAN|HGNC=28172|UniProtKB=Q96B23 Q96B23 C18orf25 PTHR16200:SF5 RING ZINC FINGER RNF111_N DOMAIN-CONTAINING PROTEIN ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=1599|UniProtKB=O60563 O60563 CCNT1 PTHR10026:SF42 CYCLIN CYCLIN-T1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of DNA-templated transcription, elongation#GO:0032784;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 kinase activator#PC00138 HUMAN|HGNC=4750|UniProtKB=Q99879 Q99879 H2BC14 PTHR23428:SF232 HISTONE H2B HISTONE H2B TYPE 1-M nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=12874|UniProtKB=O60481 O60481 ZIC3 PTHR19818:SF25 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=39080|UniProtKB=B7U540 B7U540 KCNJ18 PTHR11767:SF14 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 12-RELATED cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=8541|UniProtKB=P41231 P41231 P2RY2 PTHR24231:SF17 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 2 G-protein coupled receptor#PC00021 HUMAN|HGNC=23068|UniProtKB=P0DI81 P0DI81 TRAPPC2 PTHR12403:SF30 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-RELATED localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 HUMAN|HGNC=16473|UniProtKB=Q8N427 Q8N427 NME8 PTHR46135:SF2 NME/NM23 FAMILY MEMBER 8 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=15762|UniProtKB=Q9BZJ0 Q9BZJ0 CRNKL1 PTHR11246:SF3 PRE-MRNA SPLICING FACTOR CROOKED NECK-LIKE PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Lsm2-8 complex#GO:0120115;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974 RNA splicing factor#PC00148 HUMAN|HGNC=26684|UniProtKB=Q8NDM7 Q8NDM7 CFAP43 PTHR14885:SF1 UNCHARACTERIZED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=17791|UniProtKB=O95759 O95759 TBC1D8 PTHR22957:SF260 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 8 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=12468|UniProtKB=P0CG48 P0CG48 UBC PTHR10666:SF277 UBIQUITIN POLYUBIQUITIN-C enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=24181|UniProtKB=Q7Z5L3 Q7Z5L3 C1QL2 PTHR22923:SF69 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 2 HUMAN|HGNC=20951|UniProtKB=Q9C009 Q9C009 FOXQ1 PTHR11829:SF206 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN Q1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=3944|UniProtKB=Q92837 Q92837 FRAT1 PTHR35154:SF1 GBP PROTEIN PROTO-ONCOGENE FRAT1 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of Wnt signaling pathway#GO:0030177;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=12732|UniProtKB=Q92558 Q92558 WASF1 PTHR12902:SF8 WASP-1 WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER 1 protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cell leading edge#GO:0031252;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 HUMAN|HGNC=16805|UniProtKB=Q2TBC4 Q2TBC4 PRICKLE4 PTHR24214:SF34 PDZ AND LIM DOMAIN PROTEIN ZASP PRICKLE-LIKE PROTEIN 4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=9806|UniProtKB=O60671 O60671 RAD1 PTHR10870:SF0 CELL CYCLE CHECKPOINT PROTEIN RAD1 CELL CYCLE CHECKPOINT PROTEIN RAD1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;cellular macromolecule metabolic process#GO:0044260;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA damage checkpoint#GO:0000077;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 exodeoxyribonuclease#PC00098 HUMAN|HGNC=29674|UniProtKB=O75452 O75452 RDH16 PTHR43313:SF11 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 16 dehydrogenase#PC00092 HUMAN|HGNC=26777|UniProtKB=Q3SY69 Q3SY69 ALDH1L2 PTHR11699:SF131 ALDEHYDE DEHYDROGENASE-RELATED MITOCHONDRIAL 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=8538|UniProtKB=O15547 O15547 P2RX6 PTHR10125:SF21 P2X PURINOCEPTOR P2X PURINOCEPTOR 6 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=39941|UniProtKB=P0CW20 P0CW20 LIMS4 PTHR24210:SF11 LIM DOMAIN-CONTAINING PROTEIN LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 1-RELATED regulation of cell morphogenesis involved in differentiation#GO:0010769;signal transduction#GO:0007165;positive regulation of cell-substrate adhesion#GO:0010811;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of signal transduction#GO:0009967;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;substrate adhesion-dependent cell spreading#GO:0034446;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;integrin-mediated signaling pathway#GO:0007229;regulation of cell adhesion#GO:0030155;positive regulation of cell development#GO:0010720;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cell-cell junction organization#GO:0045216;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;cell junction organization#GO:0034330;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cell adhesion#GO:0045785 cytoplasm#GO:0005737;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 HUMAN|HGNC=11046|UniProtKB=Q9NSD5 Q9NSD5 SLC6A13 PTHR11616:SF111 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;neurotransmitter binding#GO:0042165;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=1817|UniProtKB=P06731 P06731 CEACAM5 PTHR44337:SF21 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 5 HUMAN|HGNC=14432|UniProtKB=Q96Q45 Q96Q45 TMEM237 PTHR28388:SF1 TRANSMEMBRANE PROTEIN 237 TRANSMEMBRANE PROTEIN 237 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 HUMAN|HGNC=24448|UniProtKB=Q9NRP0 Q9NRP0 OSTC PTHR13160:SF9 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;oligosaccharyltransferase complex#GO:0008250;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=7781|UniProtKB=Q14494 Q14494 NFE2L1 PTHR24411:SF31 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR ENDOPLASMIC RETICULUM MEMBRANE SENSOR NFE2L1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=11596|UniProtKB=O60806 O60806 TBX19 PTHR11267:SF114 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX19 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;ectoderm formation#GO:0001705;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;mesoderm morphogenesis#GO:0048332;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;ectoderm development#GO:0007398;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;epithelium development#GO:0060429;mesoderm formation#GO:0001707;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;endoderm formation#GO:0001706;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;mesoderm development#GO:0007498;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=3299|UniProtKB=P55010 P55010 EIF5 PTHR23001:SF22 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 5 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;RNA binding#GO:0003723;translation regulator activity#GO:0045182;translation initiation factor binding#GO:0031369;purine nucleotide binding#GO:0017076;GTPase regulator activity#GO:0030695;translation initiation factor activity#GO:0003743;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;anion binding#GO:0043168;nucleoside-triphosphatase activity#GO:0017111 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=18481|UniProtKB=Q9Y487 Q9Y487 ATP6V0A2 PTHR11629:SF22 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A2 inorganic molecular entity transmembrane transporter activity#GO:0015318;binding#GO:0005488;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;enzyme binding#GO:0019899;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 pH reduction#GO:0045851;regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;regulation of cellular pH#GO:0030641;vacuolar acidification#GO:0007035 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ATP synthase#PC00002 HUMAN|HGNC=11302|UniProtKB=Q9UHB9 Q9UHB9 SRP68 PTHR12860:SF0 SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=14945|UniProtKB=B7ZBB8 B7ZBB8 PPP1R3G PTHR12307:SF7 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3G phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase 1 binding#GO:0008157;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 monosaccharide metabolic process#GO:0005996;glucan metabolic process#GO:0044042;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;energy derivation by oxidation of organic compounds#GO:0015980;regulation of biological process#GO:0050789;cellular glucan metabolic process#GO:0006073;glucan biosynthetic process#GO:0009250;regulation of biosynthetic process#GO:0009889;oxidation-reduction process#GO:0055114;regulation of macromolecule biosynthetic process#GO:0010556;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;glycogen biosynthetic process#GO:0005978;regulation of glucose metabolic process#GO:0010906;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;polysaccharide metabolic process#GO:0005976;regulation of cellular biosynthetic process#GO:0031326;cellular carbohydrate metabolic process#GO:0044262;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;hexose metabolic process#GO:0019318;energy reserve metabolic process#GO:0006112;cellular polysaccharide biosynthetic process#GO:0033692;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular polysaccharide metabolic process#GO:0044264;small molecule metabolic process#GO:0044281 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 phosphatase modulator#PC00184 HUMAN|HGNC=11865|UniProtKB=Q99805 Q99805 TM9SF2 PTHR10766:SF36 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=8659|UniProtKB=O60245 O60245 PCDH7 PTHR24028:SF253 CADHERIN-87A PROTOCADHERIN-7 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=4469|UniProtKB=P49685 P49685 GPR15 PTHR24228:SF10 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTOR 15 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=28442|UniProtKB=Q8N7B6 Q8N7B6 PACRGL PTHR21207:SF1 PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED PACRG-LIKE PROTEIN HUMAN|HGNC=25727|UniProtKB=Q8TAP6 Q8TAP6 CEP76 PTHR46436:SF1 CENTROSOMAL PROTEIN OF 76 KDA CENTROSOMAL PROTEIN OF 76 KDA HUMAN|HGNC=10676|UniProtKB=Q9HCN8 Q9HCN8 SDF2L1 PTHR10050:SF51 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 1-RELATED transferase#PC00220 HUMAN|HGNC=2895|UniProtKB=Q9UNE0 Q9UNE0 EDAR PTHR12120:SF9 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER EDAR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=10475|UniProtKB=Q9Y230 Q9Y230 RUVBL2 PTHR11093:SF2 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 2 pyrophosphatase activity#GO:0016462;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;ribonucleoprotein complex subunit organization#GO:0071826;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;Ino80 complex#GO:0031011;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 HUMAN|HGNC=14513|UniProtKB=Q9Y2Q9 Q9Y2Q9 MRPS28 PTHR13447:SF2 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 28S RIBOSOMAL PROTEIN S28, MITOCHONDRIAL membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 HUMAN|HGNC=2433|UniProtKB=P07333 P07333 CSF1R PTHR24416:SF47 TYROSINE-PROTEIN KINASE RECEPTOR MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;osteoclast differentiation#GO:0030316;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;immune system development#GO:0002520;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=35158|UniProtKB=A8MYZ5 A8MYZ5 IQCF6 PTHR21633:SF15 IQ MOTIF CONTAINING F IQ DOMAIN-CONTAINING PROTEIN F6 protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 HUMAN|HGNC=29016|UniProtKB=O15063 O15063 GARRE1 PTHR15703:SF3 RIKEN CDNA 4931406P16 GENE GRANULE ASSOCIATED RAC AND RHOG EFFECTOR PROTEIN 1 HUMAN|HGNC=642|UniProtKB=O94778 O94778 AQP8 PTHR45665:SF9 AQUAPORIN-8 AQUAPORIN-8 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 HUMAN|HGNC=16927|UniProtKB=Q9BYQ3 Q9BYQ3 KRTAP9-3 PTHR23262:SF210 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-3-RELATED HUMAN|HGNC=1437|UniProtKB=P01258 P01258 CALCA PTHR10505:SF16 CALCITONIN-RELATED CALCITONIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 peptide hormone#PC00179 CCKR signaling map#P06959>CALCA#G07282;CCKR signaling map#P06959>CALCA#G06988 HUMAN|HGNC=19594|UniProtKB=Q8NG81 Q8NG81 OR2M7 PTHR26453:SF314 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2M7 transmembrane signal receptor#PC00197 HUMAN|HGNC=672|UniProtKB=P84095 P84095 RHOG PTHR24072:SF158 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOG GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Rac#P00564;Huntington disease#P00029>Rac#P00775;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834 HUMAN|HGNC=12266|UniProtKB=O43280 O43280 TREH PTHR23403:SF1 TREHALASE TREHALASE HUMAN|HGNC=14708|UniProtKB=Q9Y5P0 Q9Y5P0 OR51B4 PTHR26450:SF154 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B4 transmembrane signal receptor#PC00197 HUMAN|HGNC=2090|UniProtKB=P09496 P09496 CLTA PTHR10639:SF1 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN A protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;organelle organization#GO:0006996;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;protein-containing complex subunit organization#GO:0043933 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;postsynapse#GO:0098794;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell cortex#GO:0005938;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722;Huntington disease#P00029>Clathrin#P00798 HUMAN|HGNC=3178|UniProtKB=P14138 P14138 EDN3 PTHR13874:SF11 ENDOTHELIN ENDOTHELIN-3 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 blood circulation#GO:0008015;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;system process#GO:0003008;positive regulation of molecular function#GO:0044093;regulation of blood vessel diameter#GO:0097746;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;oxidation-reduction process#GO:0055114;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;regulation of anatomical structure size#GO:0090066;cellular cation homeostasis#GO:0030003;positive regulation of catalytic activity#GO:0043085;smooth muscle contraction#GO:0006939;homeostatic process#GO:0042592;regulation of systemic arterial blood pressure#GO:0003073;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;circulatory system process#GO:0003013;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065;regulation of metabolic process#GO:0019222;muscle system process#GO:0003012;muscle contraction#GO:0006936 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 Endothelin signaling pathway#P00019>ET1-4#P00588;Endothelin signaling pathway#P00019>Big ET1-4#P00574 HUMAN|HGNC=14582|UniProtKB=Q9UQV4 Q9UQV4 LAMP3 PTHR11506:SF30 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 3 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;cellular protein localization#GO:0034613;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=29982|UniProtKB=P83859 P83859 QRFP PTHR36476:SF1 OREXIGENIC NEUROPEPTIDE QRFP OREXIGENIC NEUROPEPTIDE QRFP HUMAN|HGNC=6677|UniProtKB=P06858 P06858 LPL PTHR11610:SF3 LIPASE LIPOPROTEIN LIPASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;phospholipase activity#GO:0004620;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid catabolic process#GO:0044242;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;triglyceride metabolic process#GO:0006641;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerolipid catabolic process#GO:0046503;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143 2-arachidonoylglycerol biosynthesis#P05726>DGL#P05736 HUMAN|HGNC=248|UniProtKB=Q99541 Q99541 PLIN2 PTHR14024:SF25 PERILIPIN PERILIPIN-2 localization#GO:0051179;regulation of biological process#GO:0050789;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;maintenance of location#GO:0051235;biological regulation#GO:0065007;regulation of localization#GO:0032879;lipid localization#GO:0010876;lipid storage#GO:0019915;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29520|UniProtKB=Q86WP2 Q86WP2 GPBP1 PTHR14339:SF11 VASCULIN VASCULIN cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=39038|UniProtKB=P63145 P63145 ERVK-24 PTHR40389:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED HUMAN|HGNC=15806|UniProtKB=Q9HCZ1 Q9HCZ1 ZNF334 PTHR24377:SF116 IP01015P-RELATED ZINC FINGER PROTEIN 334 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=30253|UniProtKB=O14569 O14569 CYB561D2 PTHR15422:SF21 OS05G0565100 PROTEIN CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN 2 ferroxidase activity#GO:0004322;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=24636|UniProtKB=Q9UHB6 Q9UHB6 LIMA1 PTHR24206:SF57 OS06G0237300 PROTEIN LIM DOMAIN AND ACTIN-BINDING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament bundle organization#GO:0061572 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=20627|UniProtKB=Q9UDX3 Q9UDX3 SEC14L4 PTHR23324:SF42 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 4 HUMAN|HGNC=29511|UniProtKB=Q9UPN4 Q9UPN4 CEP131 PTHR31540:SF1 CENTROSOMAL PROTEIN OF 131 KDA CENTROSOMAL PROTEIN OF 131 KDA HUMAN|HGNC=10643|UniProtKB=P80162 P80162 CXCL6 PTHR10179:SF12 CXC CHEMOKINE C-X-C MOTIF CHEMOKINE 6 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=4488|UniProtKB=Q8NGA4 Q8NGA4 GPR32P1 PTHR24225:SF27 CHEMOTACTIC RECEPTOR G-PROTEIN COUPLED RECEPTOR 32-RELATED signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;complement binding#GO:0001848;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;immune response-regulating signaling pathway#GO:0002764;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;activation of immune response#GO:0002253;divalent inorganic cation homeostasis#GO:0072507;regulation of lipase activity#GO:0060191;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;immune response-activating signal transduction#GO:0002757;activation of phospholipase C activity#GO:0007202;regulation of immune system process#GO:0002682;regulation of hydrolase activity#GO:0051336;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;cellular cation homeostasis#GO:0030003;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;regulation of immune response#GO:0050776;positive regulation of phospholipase activity#GO:0010518;positive regulation of immune system process#GO:0002684;homeostatic process#GO:0042592;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;metal ion homeostasis#GO:0055065 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=29004|UniProtKB=O15015 O15015 ZNF646 PTHR24388:SF41 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 646 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3800|UniProtKB=Q12948 Q12948 FOXC1 PTHR11829:SF68 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN C1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=13429|UniProtKB=Q9NVW2 Q9NVW2 RLIM PTHR45931:SF4 SI:CH211-59O9.10 E3 UBIQUITIN-PROTEIN LIGASE RLIM ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;regulation of gene expression, epigenetic#GO:0040029;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=23989|UniProtKB=Q96QU6 Q96QU6 ACCS PTHR43795:SF17 BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE-LIKE PROTEIN 1 transaminase#PC00216 HUMAN|HGNC=24123|UniProtKB=Q9UPM9 Q9UPM9 B9D1 PTHR12968:SF1 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 1 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 structural protein#PC00211 HUMAN|HGNC=18602|UniProtKB=Q7RTU1 Q7RTU1 TCF23 PTHR23349:SF58 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 23 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=4377|UniProtKB=Q9P2T1 Q9P2T1 GMPR2 PTHR43170:SF4 GMP REDUCTASE GMP REDUCTASE 2 reductase#PC00198 HUMAN|HGNC=25386|UniProtKB=Q6L8Q7 Q6L8Q7 PDE12 PTHR12121:SF37 CARBON CATABOLITE REPRESSOR PROTEIN 4 2',5'-PHOSPHODIESTERASE 12 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=14545|UniProtKB=Q8IV61 Q8IV61 RASGRP3 PTHR23113:SF178 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 3 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 HUMAN|HGNC=3331|UniProtKB=P50402 P50402 EMD PTHR15171:SF2 EMERIN EMERIN HUMAN|HGNC=54|UniProtKB=O15438 O15438 ABCC3 PTHR24223:SF405 ATP-BINDING CASSETTE SUB-FAMILY C CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 2 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=13916|UniProtKB=O95445 O95445 APOM PTHR32028:SF1 APOLIPOPROTEIN M APOLIPOPROTEIN M lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;binding#GO:0005488;lipid transporter activity#GO:0005319 plasma lipoprotein particle clearance#GO:0034381;organic hydroxy compound transport#GO:0015850;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein-containing complex disassembly#GO:0032984;macromolecule localization#GO:0033036;membrane organization#GO:0061024;sterol transport#GO:0015918;transport#GO:0006810;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cholesterol transport#GO:0030301;cellular component disassembly#GO:0022411;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;vesicle organization#GO:0016050;lipid localization#GO:0010876;receptor-mediated endocytosis#GO:0006898;protein-containing complex subunit organization#GO:0043933 cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;high-density lipoprotein particle#GO:0034364;extracellular region#GO:0005576 apolipoprotein#PC00052 HUMAN|HGNC=13027|UniProtKB=Q14588 Q14588 ZNF234 PTHR24377:SF195 IP01015P-RELATED ZINC FINGER PROTEIN 234 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19714|UniProtKB=Q8NEL9 Q8NEL9 DDHD1 PTHR23509:SF32 PA-PL1 PHOSPHOLIPASE FAMILY PHOSPHOLIPASE DDHD1 hydrolase activity#GO:0016787;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phospholipase#PC00186 HUMAN|HGNC=39042|UniProtKB=P60509 P60509 ERVPABLB-1 PTHR10424:SF71 VIRAL ENVELOPE PROTEIN ENDOGENOUS RETROVIRUS GROUP PABLB MEMBER 1 ENV POLYPROTEIN viral or transposable element protein#PC00237 HUMAN|HGNC=9884|UniProtKB=P06400 P06400 RB1 PTHR13742:SF17 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-ASSOCIATED PROTEIN nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;activating transcription factor binding#GO:0033613;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;developmental process#GO:0032502;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;G1/S transition of mitotic cell cycle#GO:0000082;cell differentiation#GO:0030154;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;negative regulation of G1/S transition of mitotic cell cycle#GO:2000134;cellular developmental process#GO:0048869;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G1/S phase transition#GO:1902806 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromatin#GO:0000785;chromosome#GO:0005694;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway feedback loops 2#P04398>Rb#P04654 HUMAN|HGNC=24148|UniProtKB=Q6AWC2 Q6AWC2 WWC2 PTHR14791:SF26 BOMB/KIRA PROTEINS PROTEIN WWC2 HUMAN|HGNC=16387|UniProtKB=Q9BZF2 Q9BZF2 OSBPL7 PTHR10972:SF85 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 7 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;cholesterol binding#GO:0015485 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=11726|UniProtKB=Q99973 Q99973 TEP1 PTHR44791:SF1 TELOMERASE PROTEIN COMPONENT 1 TEP1 TELOMERASE PROTEIN COMPONENT 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;RNA-directed DNA polymerase activity#GO:0003964;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;DNA polymerase activity#GO:0034061;telomerase RNA binding#GO:0070034;telomerase activity#GO:0003720 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;telomere maintenance#GO:0000723;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;mitotic recombination#GO:0006312;biological regulation#GO:0065007;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;telomerase holoenzyme complex#GO:0005697;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=33345|UniProtKB=A0A1W2PPF3 A0A1W2PPF3 DUXB PTHR46123:SF5 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN B homeodomain transcription factor#PC00119 HUMAN|HGNC=21420|UniProtKB=Q8IZL9 Q8IZL9 CDK20 PTHR24056:SF171 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 20 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;PDGF signaling pathway#P00047>GSK3#P01153 HUMAN|HGNC=9621|UniProtKB=Q6IBS0 Q6IBS0 TWF2 PTHR13759:SF9 TWINFILIN TWINFILIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of multicellular organismal process#GO:0051239;regulation of organelle organization#GO:0033043;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cellular macromolecule localization#GO:0070727;positive regulation of neurogenesis#GO:0050769;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;negative regulation of actin filament polymerization#GO:0030837;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;plasma membrane bounded cell projection assembly#GO:0120031;positive regulation of multicellular organismal process#GO:0051240;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;macromolecule localization#GO:0033036;positive regulation of cell projection organization#GO:0031346;cellular protein localization#GO:0034613;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;cellular component disassembly#GO:0022411;regulation of protein-containing complex assembly#GO:0043254;negative regulation of organelle organization#GO:0010639;supramolecular fiber organization#GO:0097435;neuron differentiation#GO:0030182;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;positive regulation of neuron differentiation#GO:0045666;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of actin filament length#GO:0030832;multicellular organism development#GO:0007275;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;positive regulation of developmental process#GO:0051094;cell projection assembly#GO:0030031;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;maintenance of location in cell#GO:0051651;regulation of cell projection assembly#GO:0060491;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856;myofibril#GO:0030016 non-motor actin binding protein#PC00165 HUMAN|HGNC=19072|UniProtKB=Q96J01 Q96J01 THOC3 PTHR22839:SF0 THO COMPLEX SUBUNIT 3 THO3 THO COMPLEX SUBUNIT 3 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=18744|UniProtKB=Q9GZS0 Q9GZS0 DNAI2 PTHR12442:SF7 DYNEIN INTERMEDIATE CHAIN DYNEIN INTERMEDIATE CHAIN 2, AXONEMAL dynein heavy chain binding#GO:0045504;protein binding#GO:0005515;binding#GO:0005488 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;vesicle targeting#GO:0006903;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=18041|UniProtKB=Q9NSY1 Q9NSY1 BMP2K PTHR22967:SF10 SERINE/THREONINE PROTEIN KINASE BMP-2-INDUCIBLE PROTEIN KINASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;kinase activity#GO:0016301;enzyme regulator activity#GO:0030234;protein kinase activity#GO:0004672;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;transferase activity#GO:0016740;hydrolase activity#GO:0016787;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 membrane organization#GO:0061024;positive regulation of signal transduction#GO:0009967;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;bone mineralization#GO:0030282;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;biomineral tissue development#GO:0031214;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;regulation of ossification#GO:0030278;organic substance metabolic process#GO:0071704;regulation of endocytosis#GO:0030100;regulation of multicellular organismal process#GO:0051239;clathrin-dependent endocytosis#GO:0072583;macromolecule metabolic process#GO:0043170;ossification#GO:0001503;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of receptor-mediated endocytosis#GO:0048259;signal transduction#GO:0007165;macromolecule modification#GO:0043412;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;transport#GO:0006810;protein modification process#GO:0036211;regulation of multicellular organismal development#GO:2000026;regulation of Notch signaling pathway#GO:0008593;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;regulation of transport#GO:0051049;vesicle organization#GO:0016050;phosphorylation#GO:0016310;receptor-mediated endocytosis#GO:0006898;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;biomineralization#GO:0110148;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;tissue development#GO:0009888;localization#GO:0051179;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;Notch signaling pathway#GO:0007219 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=10833|UniProtKB=Q9Y371 Q9Y371 SH3GLB1 PTHR14167:SF52 SH3 DOMAIN-CONTAINING ENDOPHILIN-B1 HUMAN|HGNC=12716|UniProtKB=Q8NER1 Q8NER1 TRPV1 PTHR10582:SF17 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;divalent metal ion transport#GO:0070838;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=12004|UniProtKB=Q13641 Q13641 TPBG PTHR24364:SF17 LP06937P TROPHOBLAST GLYCOPROTEIN HUMAN|HGNC=9772|UniProtKB=Q13637 Q13637 RAB32 PTHR24073:SF1176 DRAB5-RELATED RAS-RELATED PROTEIN RAB-32 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;pigmentation#GO:0043473;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;melanosome organization#GO:0032438;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;mitochondrion#GO:0005739;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=15757|UniProtKB=Q9P1W8 Q9P1W8 SIRPG PTHR19971:SF6 SIGNAL-REGULATORY PROTEIN BETA SIGNAL-REGULATORY PROTEIN GAMMA regulation of cell-cell adhesion#GO:0022407;transport#GO:0006810;biological adhesion#GO:0022610;regulation of localization#GO:0032879;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;regulation of vesicle-mediated transport#GO:0060627;leukocyte cell-cell adhesion#GO:0007159;positive regulation of leukocyte activation#GO:0002696;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;lymphocyte activation#GO:0046649;phagocytosis#GO:0006909;positive regulation of immune system process#GO:0002684;vesicle-mediated transport#GO:0016192;cell-cell adhesion#GO:0098609;positive regulation of transport#GO:0051050;cell adhesion#GO:0007155;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of T cell activation#GO:0050870;positive regulation of cell adhesion#GO:0045785;positive regulation of cell activation#GO:0050867;positive regulation of cell-cell adhesion#GO:0022409 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=5856|UniProtKB=P0DOY2 P0DOY2 IGLC2 PTHR23266:SF283 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA CONSTANT 2-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=9329|UniProtKB=P50391 P50391 NPY4R PTHR24235:SF25 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 4-RELATED neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=17233|UniProtKB=Q96JJ3 Q96JJ3 ELMO2 PTHR12771:SF8 ENGULFMENT AND CELL MOTILITY ENGULFMENT AND CELL MOTILITY PROTEIN 2 Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;locomotion#GO:0040011 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>ELMO#P00917 HUMAN|HGNC=30350|UniProtKB=Q9H9Y2 Q9H9Y2 RPF1 PTHR22734:SF3 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 RIBOSOME PRODUCTION FACTOR 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA splicing factor#PC00148 HUMAN|HGNC=34454|UniProtKB=A6NI56 A6NI56 CCDC154 PTHR35153:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 154 COILED-COIL DOMAIN-CONTAINING PROTEIN 154 HUMAN|HGNC=15467|UniProtKB=Q8TF09 Q8TF09 DYNLRB2 PTHR10779:SF3 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 protein binding#GO:0005515;binding#GO:0005488 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=9905|UniProtKB=Q9Y5S9 Q9Y5S9 RBM8A PTHR45894:SF1 RNA-BINDING PROTEIN 8A RNA-BINDING PROTEIN 8A RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;alternative mRNA splicing, via spliceosome#GO:0000380;catabolic process#GO:0009056;regulation of mRNA processing#GO:0050684;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;cellular catabolic process#GO:0044248;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;mRNA processing#GO:0006397;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;RNA splicing, via transesterification reactions#GO:0000375;cellular macromolecule catabolic process#GO:0044265;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;exon-exon junction complex#GO:0035145;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7669|UniProtKB=Q15596 Q15596 NCOA2 PTHR10684:SF2 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;binding#GO:0005488;transcription coactivator activity#GO:0003713;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;nuclear receptor transcription coactivator activity#GO:0030374;molecular function regulator#GO:0098772;protein binding#GO:0005515;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;DNA-binding transcription factor binding#GO:0140297 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=26458|UniProtKB=Q96N21 Q96N21 TEPSIN PTHR21514:SF0 UNCHARACTERIZED AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN HUMAN|HGNC=28400|UniProtKB=Q5DJT8 Q5DJT8 CT45A2 PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED CANCER/TESTIS ANTIGEN FAMILY 45 MEMBER A1-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 RNA helicase#PC00032 HUMAN|HGNC=11838|UniProtKB=Q04725 Q04725 TLE2 PTHR10814:SF4 TRANSDUCIN-LIKE ENHANCER PROTEIN TLE FAMILY MEMBER 5-RELATED repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein binding#GO:0005515;molecular function regulator#GO:0098772;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 HUMAN|HGNC=434|UniProtKB=O15296 O15296 ALOX15B PTHR11771:SF161 LIPOXYGENASE POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX15B oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;oxidation-reduction process#GO:0055114;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxygenase#PC00177 HUMAN|HGNC=23330|UniProtKB=Q8N554 Q8N554 ZNF276 PTHR24406:SF3 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER PROTEIN 276 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular#GO:0005622;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=33186|UniProtKB=Q6ZNG2 Q6ZNG2 DBX2 PTHR24331:SF4 DBX HOMEOBOX PROTEIN DBX2 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=14273|UniProtKB=Q8N9W6 Q8N9W6 BOLL PTHR11176:SF10 BOULE-RELATED PROTEIN BOULE-LIKE RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of translational initiation#GO:0045948;gene expression#GO:0010467;regulation of translational initiation#GO:0006446;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;translational initiation#GO:0006413;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=19267|UniProtKB=Q8NFP4 Q8NFP4 MDGA1 PTHR23282:SF123 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 1 HUMAN|HGNC=1780|UniProtKB=P50750 P50750 CDK9 PTHR24056:SF233 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 9 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;phosphorylation of RNA polymerase II C-terminal domain#GO:0070816;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of transcription elongation from RNA polymerase II promoter#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of DNA-templated transcription, elongation#GO:0032784;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of transcription elongation from RNA polymerase II promoter#GO:0034243;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;transcription elongation from RNA polymerase II promoter#GO:0006368;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 non-receptor serine/threonine protein kinase#PC00167 Cell cycle#P00013>Cdk4/6#P00479 HUMAN|HGNC=14907|UniProtKB=A6NI15 A6NI15 MSGN1 PTHR20937:SF4 IP14615P MESOGENIN-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;ectoderm formation#GO:0001705;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;mesoderm morphogenesis#GO:0048332;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;ectoderm development#GO:0007398;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;mesoderm formation#GO:0001707;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;endoderm formation#GO:0001706;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of RNA metabolic process#GO:0051252;mesoderm development#GO:0007498;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=3049|UniProtKB=Q14126 Q14126 DSG2 PTHR24025:SF1 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cadherin#PC00057 HUMAN|HGNC=26521|UniProtKB=Q8IVV2 Q8IVV2 LOXHD1 PTHR45901:SF3 PROTEIN CBG12474 LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=26834|UniProtKB=Q8NCX0 Q8NCX0 CCDC150 PTHR35352:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 150 COILED-COIL DOMAIN-CONTAINING PROTEIN 150 HUMAN|HGNC=26640|UniProtKB=Q8N8Q3 Q8N8Q3 ENDOV PTHR28511:SF1 ENDONUCLEASE V ENDONUCLEASE V catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;endoribonuclease activity#GO:0004521;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363 HUMAN|HGNC=29419|UniProtKB=Q5JPH6 Q5JPH6 EARS2 PTHR43311:SF3 GLUTAMATE--TRNA LIGASE GLUTAMATE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 HUMAN|HGNC=15517|UniProtKB=Q9H1B5 Q9H1B5 XYLT2 PTHR46025:SF1 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;UDP-xylosyltransferase activity#GO:0035252;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity, acting on a protein#GO:0140096;xylosyltransferase activity#GO:0042285 glycoprotein biosynthetic process#GO:0009101;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;chondroitin sulfate proteoglycan metabolic process#GO:0050654;carbohydrate derivative biosynthetic process#GO:1901137;heparan sulfate proteoglycan metabolic process#GO:0030201;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 transferase#PC00220 HUMAN|HGNC=23235|UniProtKB=Q2KHN1 Q2KHN1 RNF151 PTHR15315:SF64 RING FINGER PROTEIN 41, 151 RING FINGER PROTEIN 151 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=29936|UniProtKB=Q8NA56 Q8NA56 TTC29 PTHR46630:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 29 TETRATRICOPEPTIDE REPEAT PROTEIN 29 HUMAN|HGNC=11188|UniProtKB=Q07890 Q07890 SOS2 PTHR23113:SF150 GUANINE NUCLEOTIDE EXCHANGE FACTOR SON OF SEVENLESS HOMOLOG 2 guanyl-nucleotide exchange factor#PC00113 PI3 kinase pathway#P00048>SOS#P01185;T cell activation#P00053>SOS#P01307;Angiogenesis#P00005>SOS-1#P00193;Integrin signalling pathway#P00034>SOS#P00920;PDGF signaling pathway#P00047>SOS#P01159;B cell activation#P00010>SOS#P00379;Ras Pathway#P04393>SOS#P04552;Interleukin signaling pathway#P00036>SOS#P00981;Gonadotropin-releasing hormone receptor pathway#P06664>Sos#P06849;FGF signaling pathway#P00021>SOS#P00641;EGF receptor signaling pathway#P00018>SOS#P00558;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883 HUMAN|HGNC=3611|UniProtKB=P30273 P30273 FCER1G PTHR16803:SF0 HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR GAMMA-SUBUNIT HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT GAMMA immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=17146|UniProtKB=Q9Y2Y0 Q9Y2Y0 ARL2BP PTHR15487:SF5 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;peptidyl-tyrosine phosphorylation#GO:0018108;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of receptor signaling pathway via STAT#GO:1904894;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;tyrosine phosphorylation of STAT protein#GO:0007260;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular macromolecule localization#GO:0070727;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein localization to nucleus#GO:0034504;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;protein localization to organelle#GO:0033365;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;peptidyl-tyrosine modification#GO:0018212;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of macromolecule metabolic process#GO:0060255;maintenance of location in cell#GO:0051651;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 membrane-enclosed lumen#GO:0031974;envelope#GO:0031975;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 HUMAN|HGNC=17837|UniProtKB=P0C860 P0C860 MSL3P1 PTHR10880:SF37 MORTALITY FACTOR 4-LIKE PROTEIN MALE-SPECIFIC LETHAL-3 PROTEIN-LIKE 2-RELATED negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;histone H4 acetylation#GO:0043967;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;peptidyl-lysine acetylation#GO:0018394;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;histone H4-K16 acetylation#GO:0043984;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=4844|UniProtKB=P14317 P14317 HCLS1 PTHR10829:SF5 CORTACTIN AND DREBRIN HEMATOPOIETIC LINEAGE CELL-SPECIFIC PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;dendrite development#GO:0016358;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;dendritic spine organization#GO:0097061;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;protein-containing complex subunit organization#GO:0043933;positive regulation of growth#GO:0045927;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular protein-containing complex assembly#GO:0034622;neuron projection extension#GO:1990138;regulation of multicellular organismal process#GO:0051239;regulation of dendritic spine development#GO:0060998;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;synapse organization#GO:0050808;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;regulation of synapse structure or activity#GO:0050803;positive regulation of neuron projection development#GO:0010976;positive regulation of cell growth#GO:0030307;positive regulation of multicellular organismal process#GO:0051240;regulation of dendrite morphogenesis#GO:0048814;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;positive regulation of cell projection organization#GO:0031346;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;growth#GO:0040007;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;system development#GO:0048731;regulation of protein-containing complex assembly#GO:0043254;axon extension#GO:0048675;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;neuron differentiation#GO:0030182;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of protein polymerization#GO:0032271;cell part morphogenesis#GO:0032990;regulation of cell growth#GO:0001558;regulation of anatomical structure size#GO:0090066;positive regulation of neuron differentiation#GO:0045666;developmental cell growth#GO:0048588;developmental growth involved in morphogenesis#GO:0060560;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;developmental growth#GO:0048589;regulation of actin filament length#GO:0030832;multicellular organism development#GO:0007275;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;cell growth#GO:0016049;dendrite morphogenesis#GO:0048813;positive regulation of developmental process#GO:0051094;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of supramolecular fiber organization#GO:1902903;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cortical actin cytoskeleton#GO:0030864;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;cell cortex#GO:0005938;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;neuron projection#GO:0043005;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 non-motor actin binding protein#PC00165 HUMAN|HGNC=7773|UniProtKB=P35240 P35240 NF2 PTHR23281:SF23 MERLIN/MOESIN/EZRIN/RADIXIN MERLIN actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=31424|UniProtKB=Q8N7I0 Q8N7I0 GVQW1 PTHR46254:SF3 PROTEIN GVQW1-RELATED PROTEIN GVQW1 HUMAN|HGNC=40910|UniProtKB=H0UI37 H0UI37 TSTD3 PTHR44086:SF1 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3 transferase#PC00220 HUMAN|HGNC=4081|UniProtKB=P18505 P18505 GABRB1 PTHR18945:SF429 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-1 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;system process#GO:0003008;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=53781|UniProtKB=W6CW81 W6CW81 PYDC5 PTHR12200:SF17 INTERFERON-INDUCIBLE PROTEIN AIM2 FAMILY MEMBER INTERFERON-INDUCIBLE PROTEIN AIM2-RELATED nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 response to organic substance#GO:0010033;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cellular process#GO:0009987 DNA-binding transcription factor#PC00218 HUMAN|HGNC=7988|UniProtKB=Q86VF7 Q86VF7 NRAP PTHR11039:SF39 NEBULIN NEBULIN-RELATED-ANCHORING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;animal organ development#GO:0048513;developmental process#GO:0032502;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cardiac muscle cell development#GO:0055013;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cardiocyte differentiation#GO:0035051;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;Z disc#GO:0030018;intracellular#GO:0005622;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;I band#GO:0031674 HUMAN|HGNC=3987|UniProtKB=Q9BXU8 Q9BXU8 FTHL17 PTHR11431:SF97 FERRITIN FERRITIN HEAVY POLYPEPTIDE-LIKE 17-RELATED cation binding#GO:0043169;ferrous iron binding#GO:0008198;ferroxidase activity#GO:0004322;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;cellular cation homeostasis#GO:0030003;transition metal ion homeostasis#GO:0055076;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular iron ion homeostasis#GO:0006879;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;iron ion homeostasis#GO:0055072;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 storage protein#PC00210 HUMAN|HGNC=29397|UniProtKB=Q14DG7 Q14DG7 TMEM132B PTHR13388:SF12 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 132B HUMAN|HGNC=18313|UniProtKB=Q96L33 Q96L33 RHOV PTHR24072:SF144 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOV GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;membrane organization#GO:0061024;transport#GO:0006810;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;vesicle organization#GO:0016050;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;phagocytosis#GO:0006909;regulation of organelle organization#GO:0033043;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036;apoptotic cell clearance#GO:0043277 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 small GTPase#PC00208 Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Axon guidance mediated by semaphorins#P00007>Rac#P00340;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by netrin#P00009>Rac#P00366;B cell activation#P00010>Rac#P00385;Integrin signalling pathway#P00034>Rac#P00927;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;FGF signaling pathway#P00021>Rac#P00645 HUMAN|HGNC=17058|UniProtKB=Q6ICL7 Q6ICL7 SLC35E4 PTHR11132:SF293 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E4 secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=48813|UniProtKB=B2RXH8 B2RXH8 HNRNPCL2 PTHR13968:SF17 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN C-LIKE 1-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=24767|UniProtKB=Q6ZV70 Q6ZV70 LANCL3 PTHR12736:SF7 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=20982|UniProtKB=Q9NRG4 Q9NRG4 SMYD2 PTHR12197:SF193 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD N-LYSINE METHYLTRANSFERASE SMYD2 N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone methylation#GO:0016571;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;histone lysine methylation#GO:0034968;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=17427|UniProtKB=Q92784 Q92784 DPF3 PTHR10615:SF120 HISTONE ACETYLTRANSFERASE ZINC FINGER PROTEIN DPF3 molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|Ensembl=ENSG00000278414|UniProtKB=A0A0G2JN68 A0A0G2JN68 ENSG00000278414 PTHR11738:SF169 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 2DL5A-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=14245|UniProtKB=O95149 O95149 SNUPN PTHR13403:SF6 SNURPORTIN1 RNUT1 PROTEIN RNA, U TRANSPORTER 1 SNURPORTIN-1 transporter#PC00227 HUMAN|HGNC=1634|UniProtKB=P06126 P06126 CD1A PTHR16675:SF160 MHC CLASS I-RELATED T-CELL SURFACE GLYCOPROTEIN CD1A lipid binding#GO:0008289;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 immune response#GO:0006955;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;T cell mediated immunity#GO:0002456;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=15974|UniProtKB=Q9C040 Q9C040 TRIM2 PTHR24104:SF24 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 2 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 ubiquitin-protein ligase#PC00234 Alzheimer disease-presenilin pathway#P00004>HAC1#P00131 HUMAN|HGNC=7944|UniProtKB=P20594 P20594 NPR2 PTHR11920:SF494 GUANYLYL CYCLASE ATRIAL NATRIURETIC PEPTIDE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;organophosphate biosynthetic process#GO:0090407;cyclic nucleotide metabolic process#GO:0009187;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 guanylate cyclase#PC00114 Gonadotropin-releasing hormone receptor pathway#P06664>Npr2#P06796;Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 HUMAN|HGNC=17688|UniProtKB=P78346 P78346 RPP30 PTHR13031:SF0 RIBONUCLEASE P SUBUNIT P30 RIBONUCLEASE P PROTEIN SUBUNIT P30 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endoribonuclease activity#GO:0004521;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;heterocyclic compound binding#GO:1901363 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;ribonuclease P complex#GO:0030677;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 endoribonuclease#PC00094 HUMAN|HGNC=14553|UniProtKB=Q7Z4F1 Q7Z4F1 LRP10 PTHR24270:SF17 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 10 apolipoprotein#PC00052 HUMAN|HGNC=3392|UniProtKB=P54762 P54762 EPHB1 PTHR24416:SF173 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-B RECEPTOR 1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 HUMAN|HGNC=15432|UniProtKB=Q96R08 Q96R08 OR5B12 PTHR48018:SF51 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5B12 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=21037|UniProtKB=Q8TBC5 Q8TBC5 ZSCAN18 PTHR23226:SF157 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 18 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11323|UniProtKB=P43307 P43307 SSR1 PTHR12924:SF0 TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=15908|UniProtKB=P61599 P61599 NAA20 PTHR45910:SF1 N-ALPHA-ACETYLTRANSFERASE 20 N-ALPHA-ACETYLTRANSFERASE 20 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;N-acyltransferase activity#GO:0016410 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;N-terminal protein amino acid acetylation#GO:0006474;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 acetyltransferase#PC00038 HUMAN|HGNC=15622|UniProtKB=Q96RL6 Q96RL6 SIGLEC11 PTHR12035:SF127 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 11 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=25034|UniProtKB=Q5VZP5 Q5VZP5 DUSP27 PTHR45682:SF4 AGAP008228-PA INACTIVE DUAL SPECIFICITY PHOSPHATASE 27 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=23442|UniProtKB=Q5T764 Q5T764 IFIT1B PTHR10271:SF32 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 1B nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=10566|UniProtKB=P57086 P57086 SCAND1 PTHR45935:SF10 PROTEIN ZBED8-RELATED SCAN DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=16341|UniProtKB=Q96P88 Q96P88 GNRHR2 PTHR24241:SF69 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GONADOTROPIN-RELEASING HORMONE II RECEPTOR-RELATED signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=5155|UniProtKB=P05981 P05981 HPN PTHR24253:SF38 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE HEPSIN serine protease#PC00203 HUMAN|HGNC=29135|UniProtKB=Q6UB98 Q6UB98 ANKRD12 PTHR24149:SF14 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 HUMAN|HGNC=2542|UniProtKB=P43234 P43234 CTSO PTHR12411:SF837 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN O cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=19288|UniProtKB=Q8TDX5 Q8TDX5 ACMSD PTHR21240:SF27 2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 secondary metabolic process#GO:0019748;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 decarboxylase#PC00089 HUMAN|HGNC=5023|UniProtKB=P55318 P55318 FOXA3 PTHR11829:SF201 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=21148|UniProtKB=Q5XPI4 Q5XPI4 RNF123 PTHR13363:SF5 RING FINGER AND SRY DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF123 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=25203|UniProtKB=Q6PI78 Q6PI78 TMEM65 PTHR21706:SF15 TRANSMEMBRANE PROTEIN 65 TRANSMEMBRANE PROTEIN 65 HUMAN|HGNC=17699|UniProtKB=Q52WX2 Q52WX2 SBK1 PTHR24359:SF0 SERINE/THREONINE-PROTEIN KINASE SBK1 SERINE/THREONINE-PROTEIN KINASE SBK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=14410|UniProtKB=Q9H2U1 Q9H2U1 DHX36 PTHR18934:SF241 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT DNA/RNA HELICASE DHX36 nucleic acid binding#GO:0003676;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;DNA-dependent ATPase activity#GO:0008094;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;DNA helicase activity#GO:0003678;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA helicase#PC00032 HUMAN|HGNC=20391|UniProtKB=Q8IWU6 Q8IWU6 SULF1 PTHR43108:SF1 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;catalytic activity#GO:0003824 positive regulation of gene expression#GO:0010628;positive regulation of signal transduction#GO:0009967;negative regulation of cellular response to growth factor stimulus#GO:0090288;gene expression#GO:0010467;kidney development#GO:0001822;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;positive regulation of cytokine production#GO:0001819;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;fibroblast growth factor receptor signaling pathway#GO:0008543;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;carbohydrate derivative metabolic process#GO:1901135;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of Wnt signaling pathway#GO:0030177;cytokine production#GO:0001816;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;urogenital system development#GO:0001655;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;response to stimulus#GO:0050896;heparan sulfate proteoglycan metabolic process#GO:0030201;extracellular structure organization#GO:0043062;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;cell surface#GO:0009986;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 hydrolase#PC00121 HUMAN|HGNC=1639|UniProtKB=P06729 P06729 CD2 PTHR12080:SF54 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE T-CELL SURFACE ANTIGEN CD2 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=16353|UniProtKB=Q9UNF1 Q9UNF1 MAGED2 PTHR11736:SF11 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN D2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20898|UniProtKB=Q6PCE3 Q6PCE3 PGM2L1 PTHR45745:SF2 PHOSPHOMANNOMUTASE 45A GLUCOSE 1,6-BISPHOSPHATE SYNTHASE cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 mutase#PC00160 HUMAN|HGNC=33624|UniProtKB=Q5TBC7 Q5TBC7 BCL2L15 PTHR36466:SF1 BCL-2-LIKE PROTEIN 15 BCL-2-LIKE PROTEIN 15 HUMAN|Ensembl=ENSG00000267221|UniProtKB=A0A1B0GUU1 A0A1B0GUU1 C17orf113 PTHR46880:SF6 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE PROTEIN C17ORF113 HUMAN|HGNC=25091|UniProtKB=Q86VM9 Q86VM9 ZC3H18 PTHR46582:SF1 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 HUMAN|HGNC=23258|UniProtKB=Q96JC4 Q96JC4 ZNF479 PTHR24384:SF224 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 479 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=4740|UniProtKB=O75367 O75367 MACROH2A1 PTHR23430:SF20 HISTONE H2A CORE HISTONE MACRO-H2A.1 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=6258|UniProtKB=Q14500 Q14500 KCNJ12 PTHR11767:SF14 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 12-RELATED cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=25160|UniProtKB=Q96EK9 Q96EK9 KTI12 PTHR12435:SF2 UNCHARACTERIZED PROTEIN KTI12 HOMOLOG HUMAN|HGNC=28660|UniProtKB=Q9BUE6 Q9BUE6 ISCA1 PTHR10072:SF41 IRON-SULFUR CLUSTER ASSEMBLY PROTEIN IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL metal cluster binding#GO:0051540;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=13006|UniProtKB=Q9UL59 Q9UL59 ZNF214 PTHR24377:SF660 IP01015P-RELATED ZINC FINGER PROTEIN 214 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=27087|UniProtKB=Q8NHV5 Q8NHV5 MOSMO PTHR31186:SF1 MODULATOR OF SMOOTHENED PROTEIN MODULATOR OF SMOOTHENED PROTEIN regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;smoothened signaling pathway#GO:0007224;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;ciliary membrane#GO:0060170;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=15523|UniProtKB=Q9Y2W7 Q9Y2W7 KCNIP3 PTHR23055:SF165 CALCIUM BINDING PROTEINS CALSENILIN HUMAN|HGNC=17311|UniProtKB=O75928 O75928 PIAS2 PTHR10782:SF12 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;RNA polymerase II transcription factor binding#GO:0001085;molecular function regulator#GO:0098772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;transcription factor binding#GO:0008134 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 JAK/STAT signaling pathway#P00038>PIAS#P01031;Interferon-gamma signaling pathway#P00035>PIAS#P00958 HUMAN|HGNC=29214|UniProtKB=Q3KR37 Q3KR37 GRAMD1B PTHR23319:SF3 UNCHARACTERIZED PROTEIN ASTER-B HUMAN|HGNC=26299|UniProtKB=Q8TEC5 Q8TEC5 SH3RF2 PTHR14167:SF60 SH3 DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE SH3RF2 HUMAN|HGNC=30844|UniProtKB=Q6UXD5 Q6UXD5 SEZ6L2 PTHR45656:SF2 PROTEIN CBR-CLEC-78 SEIZURE 6-LIKE PROTEIN 2 HUMAN|HGNC=411|UniProtKB=P48448 P48448 ALDH3B2 PTHR43570:SF6 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER B2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=7547|UniProtKB=P10243 P10243 MYBL1 PTHR45614:SF9 MYB PROTEIN-RELATED MYB-RELATED PROTEIN A cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;mitotic nuclear division#GO:0140014;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|Ensembl=ENSG00000267635|UniProtKB=A0A140TA67 A0A140TA67 KRTAP9-6 PTHR23262:SF133 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-6-RELATED HUMAN|HGNC=24666|UniProtKB=Q96CS3 Q96CS3 FAF2 PTHR23322:SF95 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 2 HUMAN|HGNC=10681|UniProtKB=P21912 P21912 SDHB PTHR11921:SF29 SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL cellular respiration#GO:0045333;aerobic respiration#GO:0009060;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 dehydrogenase#PC00092 HUMAN|HGNC=26944|UniProtKB=Q9NPI0 Q9NPI0 TMEM138 PTHR13306:SF6 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 138 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=15460|UniProtKB=Q8IZS8 Q8IZS8 CACNA2D3 PTHR10166:SF25 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-3 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=13299|UniProtKB=Q9BXB1 Q9BXB1 LGR4 PTHR24372:SF67 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4 signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=19015|UniProtKB=Q96BQ3 Q96BQ3 TRIM43 PTHR24103:SF621 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 43-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9296|UniProtKB=Q12972 Q12972 PPP1R8 PTHR23308:SF28 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA splicing factor#PC00148 HUMAN|HGNC=5737|UniProtKB=P01594 P01594 IGKV1-33 PTHR23267:SF452 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-33-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=26773|UniProtKB=Q52LJ0 Q52LJ0 FAM98B PTHR31353:SF11 FAM98 PROTEIN FAM98B protein-containing complex#GO:0032991;intracellular#GO:0005622 RNA splicing factor#PC00148 HUMAN|HGNC=30914|UniProtKB=Q8TAF3 Q8TAF3 WDR48 PTHR19862:SF14 WD REPEAT-CONTAINING PROTEIN 48 WD REPEAT-CONTAINING PROTEIN 48 HUMAN|HGNC=20851|UniProtKB=Q5T0N5 Q5T0N5 FNBP1L PTHR15735:SF14 FCH AND DOUBLE SH3 DOMAINS PROTEIN FORMIN-BINDING PROTEIN 1-LIKE HUMAN|HGNC=15221|UniProtKB=Q8NH67 Q8NH67 OR52I2 PTHR26450:SF177 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52I1-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=819|UniProtKB=P20648 P20648 ATP4A PTHR43294:SF10 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;potassium ion transport#GO:0006813;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;cellular monovalent inorganic cation homeostasis#GO:0030004;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725;export from cell#GO:0140352 primary active transporter#PC00068 HUMAN|HGNC=3382|UniProtKB=Q08495 Q08495 DMTN PTHR24213:SF17 ACTIN-BINDING LIM PROTEIN DEMATIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;plasma membrane bounded cell projection assembly#GO:0120031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=27442|UniProtKB=Q8N413 Q8N413 SLC25A45 PTHR45624:SF6 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 45 ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic cation transport#GO:0015695;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812 transporter#PC00227 HUMAN|HGNC=29523|UniProtKB=Q9Y6A4 Q9Y6A4 CFAP20 PTHR12458:SF8 ORF PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 20 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of cellular component movement#GO:0051270;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;positive regulation of locomotion#GO:0040017;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;regulation of microtubule-based process#GO:0032886;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cilium movement involved in cell motility#GO:0060294;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;positive regulation of cell motility#GO:2000147;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;regulation of cell motility#GO:2000145;vesicle localization#GO:0051648;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 HUMAN|HGNC=5468|UniProtKB=P35858 P35858 IGFALS PTHR24373:SF285 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=16721|UniProtKB=A6NKQ9 A6NKQ9 CGB1 PTHR11515:SF27 GLYCOPROTEIN HORMONE BETA CHAIN CHORIOGONADOTROPIN SUBUNIT BETA 3-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular#GO:0005622 peptide hormone#PC00179 HUMAN|HGNC=921|UniProtKB=Q9P2W7 Q9P2W7 B3GAT1 PTHR10896:SF21 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;chondroitin sulfate proteoglycan metabolic process#GO:0050654;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=6176|UniProtKB=Q9BY32 Q9BY32 ITPA PTHR11067:SF9 INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN INOSINE TRIPHOSPHATE PYROPHOSPHATASE pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphate diphosphatase activity#GO:0047429;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;heterocycle catabolic process#GO:0046700;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;cellular metabolic process#GO:0044237;nucleoside triphosphate catabolic process#GO:0009143;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotide phosphatase#PC00173 Thiamin metabolism#P02780>Nucleoside triphosphatase#P03180 HUMAN|HGNC=23069|UniProtKB=O75865 O75865 TRAPPC6A PTHR12817:SF2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6A localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=15143|UniProtKB=A6NM03 A6NM03 OR2AG2 PTHR26453:SF312 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AG2 transmembrane signal receptor#PC00197 HUMAN|HGNC=2352|UniProtKB=Q03060 Q03060 CREM PTHR45879:SF4 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CAMP-RESPONSIVE ELEMENT MODULATOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Enkephalin release#P05913>CREB#P05971;Apoptosis signaling pathway#P00006>ATF#P00302;CCKR signaling map#P06959>ICER#P07027;Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 HUMAN|HGNC=8846|UniProtKB=O15055 O15055 PER2 PTHR11269:SF9 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;response to radiation#GO:0009314;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;response to light stimulus#GO:0009416;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Circadian clock system#P00015>Per#P00504;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Circadian clock system#P00015>per#G01503;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Circadian clock system#P00015>per#G01499;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 HUMAN|HGNC=14063|UniProtKB=P56524 P56524 HDAC4 PTHR48252:SF25 HISTONE DEACETYLASE 2-RELATED HISTONE DEACETYLASE 4 HUMAN|HGNC=29306|UniProtKB=Q9P1Z2 Q9P1Z2 CALCOCO1 PTHR31915:SF5 SKICH DOMAIN-CONTAINING PROTEIN CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=16093|UniProtKB=Q8NDY6 Q8NDY6 BHLHE23 PTHR19290:SF53 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 23 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=1963|UniProtKB=Q05901 Q05901 CHRNB3 PTHR18945:SF75 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-3 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;acetylcholine receptor activity#GO:0015464;molecular transducer activity#GO:0060089;acetylcholine binding#GO:0042166;ion binding#GO:0043167;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotine pharmacodynamics pathway#P06587>CHRNB3#P06612 HUMAN|HGNC=16674|UniProtKB=Q5J8X5 Q5J8X5 MS4A13 PTHR23320:SF42 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 13 transporter#PC00227 HUMAN|HGNC=18830|UniProtKB=Q5JT82 Q5JT82 KLF17 PTHR23235:SF74 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 17 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9113|UniProtKB=P29590 P29590 PML PTHR25462:SF241 BONUS, ISOFORM C-RELATED PROTEIN PML transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cell cycle arrest#GO:0007050;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;nucleus organization#GO:0006997;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;cell death#GO:0008219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;PML body#GO:0016605 p53 pathway#P00059>PML#G04701;p53 pathway#P00059>PML#P04618 HUMAN|HGNC=31951|UniProtKB=Q7Z692 Q7Z692 CEACAM19 PTHR44337:SF6 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 HUMAN|HGNC=891|UniProtKB=Q9Y679 Q9Y679 AUP1 PTHR15486:SF0 ANCIENT UBIQUITOUS PROTEIN ANCIENT UBIQUITOUS PROTEIN 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15249|UniProtKB=Q8NGI9 Q8NGI9 OR5A2 PTHR26452:SF176 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=14929|UniProtKB=Q96EB6 Q96EB6 SIRT1 PTHR48252:SF41 HISTONE DEACETYLASE 2-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1 p53 pathway#P00059>SIRT-1#P04632 HUMAN|HGNC=14501|UniProtKB=P82933 P82933 MRPS9 PTHR21569:SF39 RIBOSOMAL PROTEIN S9 28S RIBOSOMAL PROTEIN S9, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 HUMAN|HGNC=51375|UniProtKB=P0DMS9 P0DMS9 TMIGD3 PTHR11860:SF4 POLYMERIC-IMMUNOGLOBULIN RECEPTOR TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN TMIGD3 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=8942|UniProtKB=P48595 P48595 SERPINB10 PTHR11461:SF175 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B10 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=2087|UniProtKB=O96005 O96005 CLPTM1 PTHR21347:SF0 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED CLEFT LIP AND PALATE TRANSMEMBRANE PROTEIN 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=25083|UniProtKB=Q8N0Z3 Q8N0Z3 SPICE1 PTHR31167:SF3 SPINDLE AND CENTRIOLE ASSOCIATED PROTEIN 1 SPICE1 SPINDLE AND CENTRIOLE-ASSOCIATED PROTEIN 1 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;mitotic spindle organization#GO:0007052;organelle localization#GO:0051640;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;regulation of cellular component organization#GO:0051128;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;metaphase plate congression#GO:0051310;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;mitotic spindle assembly#GO:0090307;regulation of microtubule cytoskeleton organization#GO:0070507;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;spindle organization#GO:0007051;establishment of organelle localization#GO:0051656;regulation of centrosome duplication#GO:0010824;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;establishment of chromosome localization#GO:0051303;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;regulation of cell cycle process#GO:0010564;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;chromosome localization#GO:0050000 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=12135|UniProtKB=A0A075B6V5 A0A075B6V5 TRAV36DV7 PTHR19433:SF83 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 36/DELTA VARIABLE 7 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=25477|UniProtKB=Q7L5Y6 Q7L5Y6 DET1 PTHR13374:SF3 DET1 HOMOLOG DE-ETIOLATED-1 HOMOLOG DET1 HOMOLOG enzyme binding#GO:0019899;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;protein-macromolecule adaptor activity#GO:0030674 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=14884|UniProtKB=O60884 O60884 DNAJA2 PTHR43888:SF31 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 2 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=2215|UniProtKB=P27658 P27658 COL8A1 PTHR24023:SF903 COLLAGEN ALPHA COLLAGEN ALPHA-1(VIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=661|UniProtKB=Q9NP61 Q9NP61 ARFGAP3 PTHR45686:SF1 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 3 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 vesicle targeting, to, from or within Golgi#GO:0048199;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;Golgi vesicle budding#GO:0048194;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;establishment of organelle localization#GO:0051656 GTPase-activating protein#PC00257 HUMAN|HGNC=4462|UniProtKB=Q14956 Q14956 GPNMB PTHR11861:SF11 MELANOCYTE PROTEIN PMEL 17-RELATED TRANSMEMBRANE GLYCOPROTEIN NMB cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=8054|UniProtKB=P0C024 P0C024 NUDT7 PTHR12992:SF24 NUDIX HYDROLASE PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7 phosphatase#PC00181 HUMAN|HGNC=21109|UniProtKB=Q96EK7 Q96EK7 FAM120B PTHR15976:SF17 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=4268|UniProtKB=P27352 P27352 CBLIF PTHR10559:SF15 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR COBALAMIN BINDING INTRINSIC FACTOR tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;transport#GO:0006810 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=6393|UniProtKB=Q99661 Q99661 KIF2C PTHR24115:SF454 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2C pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 microtubule binding motor protein#PC00156 HUMAN|HGNC=15669|UniProtKB=Q8N103 Q8N103 TAGAP PTHR23179:SF26 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED T-CELL ACTIVATION RHO GTPASE-ACTIVATING PROTEIN GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257 HUMAN|HGNC=18657|UniProtKB=Q5SRH9 Q5SRH9 TTC39A PTHR31859:SF3 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39A HUMAN|HGNC=4901|UniProtKB=Q03014 Q03014 HHEX PTHR24324:SF5 HOMEOBOX PROTEIN HHEX HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX homeodomain transcription factor#PC00119 HUMAN|HGNC=30242|UniProtKB=Q13454 Q13454 TUSC3 PTHR12692:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED TUMOR SUPPRESSOR CANDIDATE 3 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 HUMAN|HGNC=29172|UniProtKB=Q9UPX6 Q9UPX6 MINAR1 PTHR31530:SF2 MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 MINAR1 FAMILY MEMBER MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;regulation of cell population proliferation#GO:0042127;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell population proliferation#GO:0008283;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;negative regulation of signal transduction#GO:0009968;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=6701|UniProtKB=P30533 P30533 LRPAP1 PTHR16560:SF2 ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN regulation of endocytosis#GO:0030100;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;regulation of receptor-mediated endocytosis#GO:0048259 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=25058|UniProtKB=Q6ZTW0 Q6ZTW0 TPGS1 PTHR31932:SF2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 1 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=21637|UniProtKB=Q9UPW6 Q9UPW6 SATB2 PTHR15116:SF15 DNA-BINDING PROTEIN SATB FAMILY MEMBER DNA-BINDING PROTEIN SATB2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 Lambda repressor-like transcription factor#PC00245 HUMAN|HGNC=19016|UniProtKB=Q96DX7 Q96DX7 TRIM44 PTHR24103:SF597 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 44 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=4102|UniProtKB=Q13069 Q13069 GAGE5 PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=7678|UniProtKB=Q00604 Q00604 NDP PTHR28611:SF1 NORRIN NORRIN binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=33732|UniProtKB=Q7Z4L9 Q7Z4L9 PPP1R42 PTHR45973:SF3 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 42 phosphatase modulator#PC00184 HUMAN|HGNC=32930|UniProtKB=Q6UXB1 Q6UXB1 IGFL3 PTHR34827:SF5 INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 3-RELATED INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=18181|UniProtKB=Q92529 Q92529 SHC3 PTHR10337:SF4 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 3 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Shc#P00554;PDGF signaling pathway#P00047>Shc#P01175;FGF signaling pathway#P00021>Shc#P00639 HUMAN|HGNC=25230|UniProtKB=Q5TGY3 Q5TGY3 AHDC1 PTHR15617:SF1 UNCHARACTERIZED AT-HOOK DNA-BINDING MOTIF-CONTAINING PROTEIN 1 HUMAN|HGNC=17345|UniProtKB=Q8N4E7 Q8N4E7 FTMT PTHR11431:SF30 FERRITIN FERRITIN, MITOCHONDRIAL cation binding#GO:0043169;ferrous iron binding#GO:0008198;ferroxidase activity#GO:0004322;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;cellular cation homeostasis#GO:0030003;transition metal ion homeostasis#GO:0055076;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular iron ion homeostasis#GO:0006879;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;iron ion homeostasis#GO:0055072;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 storage protein#PC00210 HUMAN|HGNC=4277|UniProtKB=Q9Y6H8 Q9Y6H8 GJA3 PTHR11984:SF12 CONNEXIN GAP JUNCTION ALPHA-3 PROTEIN gap junction#PC00105 HUMAN|HGNC=8040|UniProtKB=O95665 O95665 NTSR2 PTHR24243:SF10 G-PROTEIN COUPLED RECEPTOR NEUROTENSIN RECEPTOR TYPE 2 G-protein coupled receptor#PC00021 HUMAN|HGNC=24335|UniProtKB=Q99627 Q99627 COPS8 PTHR13339:SF0 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28835|UniProtKB=Q6NXR0 Q6NXR0 IRGC PTHR32341:SF7 INTERFERON-INDUCIBLE GTPASE INTERFERON-INDUCIBLE GTPASE 5 HUMAN|HGNC=25549|UniProtKB=P0DP57 P0DP57 SLURP2 PTHR16983:SF14 UPAR/LY6 DOMAIN-CONTAINING PROTEIN SECRETED LY-6/UPAR DOMAIN-CONTAINING PROTEIN 2 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;receptor regulator activity#GO:0030545;acetylcholine receptor activity#GO:0015464;molecular function regulator#GO:0098772;molecular transducer activity#GO:0060089;acetylcholine receptor regulator activity#GO:0030548;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;acetylcholine binding#GO:0042166;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 HUMAN|HGNC=5657|UniProtKB=P0DP08 P0DP08 IGHV4-38-2 PTHR23266:SF356 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 4-38-2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=4260|UniProtKB=P36269 P36269 GGT5 PTHR11686:SF19 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 5 PROENZYME transferase activity, transferring acyl groups#GO:0016746;hydrolase activity#GO:0016787;transferase activity#GO:0016740;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound catabolic process#GO:1901565;icosanoid biosynthetic process#GO:0046456;biosynthetic process#GO:0009058;glutathione metabolic process#GO:0006749;inflammatory response#GO:0006954;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;defense response#GO:0006952;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;fatty acid derivative metabolic process#GO:1901568;amide biosynthetic process#GO:0043604;response to stimulus#GO:0050896;peptide biosynthetic process#GO:0043043;response to stress#GO:0006950;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190 HUMAN|HGNC=53439|UniProtKB=A0A1W2PPG7 A0A1W2PPG7 GNG14 PTHR13809:SF14 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-14-RELATED protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 HUMAN|HGNC=28980|UniProtKB=Q14691 Q14691 GINS1 PTHR12914:SF2 PARTNER OF SLD5 DNA REPLICATION COMPLEX GINS PROTEIN PSF1 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organelle organization#GO:0006996;DNA biosynthetic process#GO:0071897;mitotic DNA replication#GO:1902969;cell cycle#GO:0007049;organelle fission#GO:0048285;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;pre-replicative complex#GO:0036387;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pre-replicative complex#GO:0005656;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=2173|UniProtKB=Q9P232 Q9P232 CNTN3 PTHR12231:SF224 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN CONTACTIN-3 HUMAN|HGNC=27564|UniProtKB=Q2TAC2 Q2TAC2 CCDC57 PTHR46725:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 57 COILED-COIL DOMAIN-CONTAINING PROTEIN 57 HUMAN|HGNC=253|UniProtKB=P11766 P11766 ADH5 PTHR43880:SF4 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE CLASS-3 cation binding#GO:0043169;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 response to organic substance#GO:0010033;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=15971|UniProtKB=Q99816 Q99816 TSG101 PTHR23306:SF17 TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED TUMOR SUSCEPTIBILITY GENE 101 PROTEIN ubiquitin-protein ligase#PC00234 HUMAN|HGNC=15569|UniProtKB=O75952 O75952 CABYR PTHR15494:SF0 CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;C2 axonemal microtubule#GO:1990720;B axonemal microtubule#GO:0097650;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;axonemal microtubule#GO:0005879 HUMAN|HGNC=11654|UniProtKB=Q13428 Q13428 TCOF1 PTHR20787:SF10 TREACLE TREACLE PROTEIN RNA metabolism protein#PC00031 HUMAN|HGNC=21182|UniProtKB=Q8NFH3 Q8NFH3 NUP43 PTHR22652:SF0 NUCLEOPORIN NUP43 NUCLEOPORIN NUP43 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=20248|UniProtKB=Q8IYK8 Q8IYK8 REM2 PTHR45775:SF5 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN REM 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;transporter activity#GO:0005215;channel activity#GO:0015267;calcium channel regulator activity#GO:0005246;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;channel regulator activity#GO:0016247;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=17267|UniProtKB=Q8IZP6 Q8IZP6 RNF113B PTHR12930:SF1 ZINC FINGER PROTEIN 183 RING FINGER PROTEIN 113B cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=610|UniProtKB=P02656 P02656 APOC3 PTHR14225:SF0 APOLIPOPROTEIN C-III APOLIPOPROTEIN C-III apolipoprotein#PC00052 HUMAN|HGNC=32270|UniProtKB=A8MWA6 A8MWA6 FAM90A22P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=24921|UniProtKB=Q9BQI3 Q9BQI3 EIF2AK1 PTHR11042:SF160 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=13159|UniProtKB=P51523 P51523 ZNF84 PTHR24377:SF627 IP01015P-RELATED ZINC FINGER PROTEIN 84 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4905|UniProtKB=Q9UM44 Q9UM44 HHLA2 PTHR24100:SF106 BUTYROPHILIN HERV-H LTR-ASSOCIATING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=26496|UniProtKB=A8K8V0 A8K8V0 ZNF785 PTHR24381:SF297 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 688-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15947|UniProtKB=Q9BZF9 Q9BZF9 UACA PTHR24173:SF23 FAMILY NOT NAMED UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of NIK/NF-kappaB signaling#GO:1901222;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;positive regulation of programmed cell death#GO:0043068;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;cell death#GO:0008219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;nucleic acid-templated transcription#GO:0097659;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;regulation of DNA-binding transcription factor activity#GO:0051090;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;NIK/NF-kappaB signaling#GO:0038061;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell death#GO:0010942;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17845|UniProtKB=O43704 O43704 SULT1B1 PTHR11783:SF14 SULFOTRANSFERASE SULT SULFOTRANSFERASE FAMILY CYTOSOLIC 1B MEMBER 1 transferase#PC00220 HUMAN|HGNC=26926|UniProtKB=Q8N5M9 Q8N5M9 JAGN1 PTHR20955:SF1 UNCHARACTERIZED PROTEIN JAGUNAL HOMOLOG 1 HUMAN|HGNC=21343|UniProtKB=Q86XW9 Q86XW9 NME9 PTHR46135:SF1 NME/NM23 FAMILY MEMBER 8 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 6 HUMAN|HGNC=2648|UniProtKB=P98187 P98187 CYP4F8 PTHR24291:SF141 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F8 oxygenase#PC00177 HUMAN|HGNC=27124|UniProtKB=Q96N38 Q96N38 ZNF714 PTHR24384:SF104 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 714 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=4662|UniProtKB=Q92664 Q92664 GTF3A PTHR46179:SF1 ZINC FINGER PROTEIN TRANSCRIPTION FACTOR IIIA cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=2481|UniProtKB=P01040 P01040 CSTA PTHR11414:SF20 CYSTATIN FAMILY MEMBER CYSTATIN-A cysteine-type peptidase activity#GO:0008234;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease inhibitor#PC00191 HUMAN|HGNC=14077|UniProtKB=Q9NPG2 Q9NPG2 NGB PTHR46458:SF1 BLR2807 PROTEIN NEUROGLOBIN transporter#PC00227 HUMAN|HGNC=29468|UniProtKB=Q5T750 Q5T750 XP32 PTHR23263:SF4 SMALL PROLINE-RICH PROTEIN SKIN-SPECIFIC PROTEIN 32 HUMAN|HGNC=3735|UniProtKB=O43638 O43638 FOXS1 PTHR11829:SF370 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN S1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=9202|UniProtKB=Q9Y6A1 Q9Y6A1 POMT1 PTHR10050:SF51 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 1-RELATED transferase#PC00220 HUMAN|HGNC=25224|UniProtKB=Q5VT98 Q5VT98 PRAMEF20 PTHR14224:SF93 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 20 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=16421|UniProtKB=P35712 P35712 SOX6 PTHR45789:SF1 FI18025P1 TRANSCRIPTION FACTOR SOX-6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;connective tissue development#GO:0061448;chondrocyte differentiation#GO:0002062;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;positive regulation of developmental process#GO:0051094;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;cartilage development#GO:0051216;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=31976|UniProtKB=A6NL99 A6NL99 AQP7P3 PTHR43829:SF25 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-7-LIKE PROTEIN 3-RELATED amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 HUMAN|HGNC=25969|UniProtKB=Q6ZN54 Q6ZN54 DEF8 PTHR12326:SF3 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN DIFFERENTIALLY EXPRESSED IN FDCP 8 HOMOLOG HUMAN|HGNC=6414|UniProtKB=Q99456 Q99456 KRT12 PTHR23239:SF369 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 12 HUMAN|HGNC=7216|UniProtKB=P34949 P34949 MPI PTHR10309:SF0 MANNOSE-6-PHOSPHATE ISOMERASE MANNOSE-6-PHOSPHATE ISOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;cellular aromatic compound metabolic process#GO:0006725;macromolecule glycosylation#GO:0043413;cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell wall biogenesis#GO:0042546;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;cell wall organization or biogenesis#GO:0071554;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component macromolecule biosynthetic process#GO:0070589;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;cell wall macromolecule metabolic process#GO:0044036;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cell wall macromolecule biosynthetic process#GO:0044038;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleobase-containing small molecule metabolic process#GO:0055086;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 isomerase#PC00135 Mannose metabolism#P02752>Mannose 6-P isomerase#P03017 HUMAN|HGNC=3024|UniProtKB=P35462 P35462 DRD3 PTHR24248:SF154 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(3) DOPAMINE RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Nicotine pharmacodynamics pathway#P06587>DRD2/ DRD3/ DRD4#P06603;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965 HUMAN|HGNC=25434|UniProtKB=Q9P2M1 Q9P2M1 LRP2BP PTHR44554:SF1 LRP2-BINDING PROTEIN LRP2-BINDING PROTEIN HUMAN|HGNC=29334|UniProtKB=Q9HCC9 Q9HCC9 ZFYVE28 PTHR46465:SF2 LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=12726|UniProtKB=P04275 P04275 VWF PTHR11339:SF361 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED VON WILLEBRAND FACTOR response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of biological quality#GO:0065008;biological adhesion#GO:0022610;biological regulation#GO:0065007;regulation of body fluid levels#GO:0050878;multicellular organismal process#GO:0032501;cell adhesion#GO:0007155;wound healing#GO:0042060;blood coagulation#GO:0007596;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;hemostasis#GO:0007599;coagulation#GO:0050817 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Blood coagulation#P00011>vWF#P00448 HUMAN|HGNC=25216|UniProtKB=Q9NUQ9 Q9NUQ9 CYRIB PTHR12422:SF3 UNCHARACTERIZED CYFIP-RELATED RAC1 INTERACTOR B lymphocyte activation#GO:0046649;regulation of cell-cell adhesion#GO:0022407;biological adhesion#GO:0022610;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;leukocyte cell-cell adhesion#GO:0007159;positive regulation of leukocyte activation#GO:0002696;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of leukocyte cell-cell adhesion#GO:1903037;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;positive regulation of T cell activation#GO:0050870;positive regulation of cell adhesion#GO:0045785;positive regulation of cell activation#GO:0050867;regulation of cell adhesion#GO:0030155;positive regulation of cell-cell adhesion#GO:0022409;leukocyte activation#GO:0045321;regulation of lymphocyte activation#GO:0051249;positive regulation of biological process#GO:0048518 HUMAN|HGNC=19885|UniProtKB=Q96ED9 Q96ED9 HOOK2 PTHR18947:SF37 HOOK PROTEINS PROTEIN HOOK HOMOLOG 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 membrane traffic protein#PC00150 HUMAN|HGNC=20863|UniProtKB=P0CK97 P0CK97 SLC35E2A PTHR11132:SF279 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E2A-RELATED secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=38686|UniProtKB=P0CJ87 P0CJ87 DUX4L4 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=37|UniProtKB=Q8IZY2 Q8IZY2 ABCA7 PTHR19229:SF49 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA7 signaling receptor activity#GO:0038023;binding#GO:0005488;catalytic activity#GO:0003824;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;transmembrane signaling receptor activity#GO:0004888;pyrophosphatase activity#GO:0016462;molecular adaptor activity#GO:0060090;transmembrane transporter activity#GO:0022857;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;phosphatidylcholine transporter activity#GO:0008525;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular transducer activity#GO:0060089;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;phospholipid transporter activity#GO:0005548;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;cholesterol transport#GO:0030301;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;sterol transport#GO:0015918;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=16770|UniProtKB=Q8NFY4 Q8NFY4 SEMA6D PTHR11036:SF65 SEMAPHORIN SEMAPHORIN-6D receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=29899|UniProtKB=Q96QD5 Q96QD5 DEPDC7 PTHR16206:SF9 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25171|UniProtKB=Q96CT7 Q96CT7 CCDC124 PTHR21680:SF0 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 124 HUMAN|HGNC=7607|UniProtKB=Q6PIF6 Q6PIF6 MYO7B PTHR13140:SF505 MYOSIN UNCONVENTIONAL MYOSIN-VIIB pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;sensory perception of sound#GO:0007605;animal organ development#GO:0048513;system process#GO:0003008;transport#GO:0006810;developmental process#GO:0032502;system development#GO:0048731;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;nervous system process#GO:0050877;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;sensory perception#GO:0007600;actin cytoskeleton organization#GO:0030036;sensory organ development#GO:0007423;vesicle cytoskeletal trafficking#GO:0099518 microvillus#GO:0005902;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;actin-based cell projection#GO:0098858;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=12729|UniProtKB=P23381 P23381 WARS1 PTHR10055:SF1 TRYPTOPHANYL-TRNA SYNTHETASE TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=27194|UniProtKB=Q6NVV3 Q6NVV3 NIPAL1 PTHR12570:SF13 UNCHARACTERIZED MAGNESIUM TRANSPORTER NIPA3 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=16968|UniProtKB=Q9UBL0 Q9UBL0 ARPP21 PTHR15672:SF14 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN CAMP-REGULATED PHOSPHOPROTEIN 21 HUMAN|HGNC=18758|UniProtKB=Q8IWZ6 Q8IWZ6 BBS7 PTHR16074:SF4 BARDET-BIEDL SYNDROME 7 PROTEIN BARDET-BIEDL SYNDROME 7 PROTEIN vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;BBSome#GO:0034464;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=28719|UniProtKB=Q68CZ6 Q68CZ6 HAUS3 PTHR19378:SF0 GOLGIN- RELATED HAUS AUGMIN-LIKE COMPLEX SUBUNIT 3 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;centrosome#GO:0005813 HUMAN|HGNC=33271|UniProtKB=P0DMU7 P0DMU7 CT45A6 PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED CANCER/TESTIS ANTIGEN FAMILY 45 MEMBER A1-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 RNA helicase#PC00032 HUMAN|HGNC=28788|UniProtKB=Q8NCB2 Q8NCB2 CAMKV PTHR24347:SF18 SERINE/THREONINE-PROTEIN KINASE CAM KINASE-LIKE VESICLE-ASSOCIATED PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=15018|UniProtKB=Q8NHC8 Q8NHC8 OR2T6 PTHR26453:SF57 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T6 transmembrane signal receptor#PC00197 HUMAN|HGNC=26800|UniProtKB=Q8TAB5 Q8TAB5 C1orf216 PTHR35673:SF1 UPF0500 PROTEIN C1ORF216 UPF0500 PROTEIN C1ORF216 HUMAN|HGNC=26837|UniProtKB=Q5JTC6 Q5JTC6 AMER1 PTHR22237:SF0 UNCHARACTERIZED APC MEMBRANE RECRUITMENT PROTEIN 1 phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;beta-catenin binding#GO:0008013 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=23631|UniProtKB=Q6W5P4 Q6W5P4 NPSR1 PTHR24244:SF2 NEUROPEPTIDE S RECEPTOR NEUROPEPTIDE S RECEPTOR G-protein coupled receptor#PC00021 HUMAN|HGNC=8729|UniProtKB=P12004 P12004 PCNA PTHR11352:SF5 PROLIFERATING CELL NUCLEAR ANTIGEN PROLIFERATING CELL NUCLEAR ANTIGEN molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;mismatch repair#GO:0006298;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;aromatic compound catabolic process#GO:0019439;DNA biosynthetic process#GO:0071897;organic cyclic compound catabolic process#GO:1901361;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA polymerase processivity factor#PC00015 DNA replication#P00017>PCNA#P00534 HUMAN|HGNC=688|UniProtKB=Q9H4E5 Q9H4E5 RHOJ PTHR24072:SF17 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOJ GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cell projection organization#GO:0030030;membrane organization#GO:0061024;transport#GO:0006810;Ras protein signal transduction#GO:0007265;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle organization#GO:0016050;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;endocytosis#GO:0006897;localization of cell#GO:0051674;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;cell projection assembly#GO:0030031;small GTPase mediated signal transduction#GO:0007264;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Rac#P00564;Huntington disease#P00029>Rac#P00775;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507 HUMAN|HGNC=7851|UniProtKB=Q13232 Q13232 NME3 PTHR11349:SF54 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 HUMAN|HGNC=1579|UniProtKB=P14635 P14635 CCNB1 PTHR10177:SF193 CYCLINS G2/MITOTIC-SPECIFIC CYCLIN-B1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;organelle localization#GO:0051640;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cellular protein metabolic process#GO:0044267;establishment of organelle localization#GO:0051656;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;mitotic metaphase plate congression#GO:0007080;chromosome localization#GO:0050000;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of phosphate metabolic process#GO:0019220;regulation of cyclin-dependent protein kinase activity#GO:1904029;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;metaphase plate congression#GO:0051310;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;mitotic sister chromatid segregation#GO:0000070;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of protein kinase activity#GO:0045859;establishment of chromosome localization#GO:0051303;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338 membrane-enclosed lumen#GO:0031974;microtubule organizing center#GO:0005815;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 Cell cycle#P00013>Cyclin B#P00486;p53 pathway#P00059>Cyclin B#P04614 HUMAN|HGNC=26789|UniProtKB=Q8IV20 Q8IV20 LACC1 PTHR30616:SF2 UNCHARACTERIZED PROTEIN YFIH PURINE NUCLEOSIDE PHOSPHORYLASE LACC1 copper ion binding#GO:0005507;cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;transition metal ion binding#GO:0046914 HUMAN|HGNC=28796|UniProtKB=Q96HT8 Q96HT8 MRFAP1L1 PTHR31324:SF2 MORF4 FAMILY-ASSOCIATED PROTEIN 1-RELATED MORF4 FAMILY-ASSOCIATED PROTEIN 1-LIKE 1 HUMAN|HGNC=6882|UniProtKB=Q9UQF2 Q9UQF2 MAPK8IP1 PTHR11232:SF44 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 1 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;signal transduction by protein phosphorylation#GO:0023014;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;JNK cascade#GO:0007254;stress-activated MAPK cascade#GO:0051403;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;regulation of stress-activated MAPK cascade#GO:0032872;stress-activated protein kinase signaling cascade#GO:0031098;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=22407|UniProtKB=Q9NUM4 Q9NUM4 TMEM106B PTHR28556:SF1 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106B HUMAN|HGNC=29291|UniProtKB=Q9P242 Q9P242 NYAP2 PTHR22633:SF1 NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2-RELATED NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=30602|UniProtKB=H0Y354 H0Y354 FAM72C PTHR31841:SF1 PROTEIN FAM72A-RELATED PROTEIN FAM72A-RELATED cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=9863|UniProtKB=Q13702 Q13702 RAPSN PTHR46574:SF1 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE 43 KDA RECEPTOR-ASSOCIATED PROTEIN OF THE SYNAPSE HUMAN|HGNC=25967|UniProtKB=Q9NXL6 Q9NXL6 SIDT1 PTHR12185:SF15 SID1 TRANSMEMBRANE FAMILY MEMEBER SID1 TRANSMEMBRANE FAMILY MEMBER 1 HUMAN|HGNC=18429|UniProtKB=Q14914 Q14914 PTGR1 PTHR43205:SF33 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 1 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid derivative metabolic process#GO:1901568;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 reductase#PC00198 HUMAN|HGNC=25062|UniProtKB=Q7Z7H3 Q7Z7H3 CATIP PTHR15505:SF3 RIIA DOMAIN-CONTAINING PROTEIN 1 CILIOGENESIS-ASSOCIATED TTC17-INTERACTING PROTEIN HUMAN|HGNC=11425|UniProtKB=P08842 P08842 STS PTHR42693:SF9 ARYLSULFATASE FAMILY MEMBER STERYL-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=18783|UniProtKB=Q02040 Q02040 AKAP17A PTHR12484:SF2 B-LYMPHOCYTE ANTIGEN-RELATED A-KINASE ANCHOR PROTEIN 17A protein kinase A binding#GO:0051018;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=21194|UniProtKB=Q5JWR5 Q5JWR5 DOP1A PTHR14042:SF22 DOPEY-RELATED PROTEIN DOPEY-1 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=1728|UniProtKB=P30260 P30260 CDC27 PTHR12558:SF13 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 27 HOMOLOG cell division#GO:0051301;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=4554|UniProtKB=P18283 P18283 GPX2 PTHR11592:SF36 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 2 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180 HUMAN|HGNC=9885|UniProtKB=P29374 P29374 ARID4A PTHR13964:SF26 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=26678|UniProtKB=Q7Z3K6 Q7Z3K6 MIER3 PTHR10865:SF22 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 3 repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 HUMAN|HGNC=33728|UniProtKB=A6NJB7 A6NJB7 PRR19 PTHR37346:SF1 PROLINE-RICH PROTEIN 19 PROLINE-RICH PROTEIN 19 HUMAN|HGNC=34519|UniProtKB=O60290 O60290 ZNF862 PTHR46880:SF3 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 862 HUMAN|HGNC=18187|UniProtKB=Q9HAT2 Q9HAT2 SIAE PTHR22901:SF0 SIALATE O-ACETYLESTERASE SIALATE O-ACETYLESTERASE esterase#PC00097 HUMAN|HGNC=30097|UniProtKB=O94913 O94913 PCF11 PTHR15921:SF3 PRE-MRNA CLEAVAGE COMPLEX II PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;organic cyclic compound binding#GO:0097159;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;enzyme binding#GO:0019899;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;protein binding#GO:0005515;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA 3'-end processing#GO:0031124;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA polyadenylation#GO:0006378;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA processing#GO:0006397;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=37099|UniProtKB=A6NKF7 A6NKF7 TMEM88B PTHR28628:SF2 TRANSMEMBRANE PROTEIN 88-RELATED TRANSMEMBRANE PROTEIN 88B protein binding#GO:0005515;binding#GO:0005488 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=28211|UniProtKB=Q96I45 Q96I45 TMEM141 PTHR47229:SF1 TRANSMEMBRANE PROTEIN 141 TRANSMEMBRANE PROTEIN 141 HUMAN|HGNC=6916|UniProtKB=Q9UIS9 Q9UIS9 MBD1 PTHR12396:SF26 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 1 HUMAN|HGNC=27584|UniProtKB=Q641Q3 Q641Q3 METRNL PTHR28593:SF1 METEORIN-LIKE PROTEIN METEORIN-LIKE PROTEIN binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;fat cell differentiation#GO:0045444;positive regulation of cell differentiation#GO:0045597;developmental process#GO:0032502;homeostatic process#GO:0042592;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;multicellular organismal homeostasis#GO:0048871;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=23728|UniProtKB=Q86WR7 Q86WR7 PROSER2 PTHR16095:SF9 TRANSMEMBRANE PROTEIN 143 FAMILY MEMBER PROLINE AND SERINE-RICH PROTEIN 2 HUMAN|HGNC=24191|UniProtKB=Q6UVW9 Q6UVW9 CLEC2A PTHR45710:SF22 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER A external side of plasma membrane#GO:0009897;leaflet of membrane bilayer#GO:0097478;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=30217|UniProtKB=Q9UNQ2 Q9UNQ2 DIMT1 PTHR11727:SF7 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE-RELATED catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;RNA methylation#GO:0001510 RNA methyltransferase#PC00033 HUMAN|HGNC=33833|UniProtKB=A0PJZ0 A0PJZ0 ANKRD20A5P PTHR24147:SF1 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 20A1-RELATED HUMAN|HGNC=23216|UniProtKB=Q96JG9 Q96JG9 ZNF469 PTHR21465:SF2 ZINC FINGER PROTEIN 469 ZINC FINGER PROTEIN 469 HUMAN|HGNC=10763|UniProtKB=Q9BYH1 Q9BYH1 SEZ6L PTHR45656:SF8 PROTEIN CBR-CLEC-78 C4B-BINDING PROTEIN BETA CHAIN-RELATED HUMAN|HGNC=28985|UniProtKB=Q92604 Q92604 LPGAT1 PTHR10983:SF2 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED ACYL-COA:LYSOPHOSPHATIDYLGLYCEROL ACYLTRANSFERASE 1 transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=9519|UniProtKB=P11465 P11465 PSG2 PTHR44337:SF15 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 11-RELATED HUMAN|HGNC=25022|UniProtKB=Q9GZP4 Q9GZP4 PITHD1 PTHR12175:SF1 AD039 HT014 THIOREDOXIN FAMILY TRP26 PITH DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 HUMAN|HGNC=29225|UniProtKB=Q9ULJ1 Q9ULJ1 ODF2L PTHR23162:SF7 OUTER DENSE FIBER OF SPERM TAILS 2 PROTEIN BCAP HUMAN|HGNC=9987|UniProtKB=O14593 O14593 RFXANK PTHR24124:SF4 ANKYRIN REPEAT FAMILY A DNA-BINDING PROTEIN RFXANK cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 protein-binding activity modulator#PC00095 HUMAN|HGNC=412|UniProtKB=P49189 P49189 ALDH9A1 PTHR11699:SF228 ALDEHYDE DEHYDROGENASE-RELATED 4-TRIMETHYLAMINOBUTYRALDEHYDE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=18060|UniProtKB=Q96QS3 Q96QS3 ARX PTHR24329:SF548 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=25076|UniProtKB=Q9H094 Q9H094 NBPF3 PTHR14199:SF21 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 3 HUMAN|HGNC=1697|UniProtKB=P04233 P04233 CD74 PTHR14093:SF17 HLA CLASS II GAMMA CHAIN HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;MHC protein binding#GO:0042287;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of response to DNA damage stimulus#GO:2001020;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of cytokine production involved in immune response#GO:0002718;positive regulation of protein modification process#GO:0031401;regulation of apoptotic signaling pathway#GO:2001233;production of molecular mediator of immune response#GO:0002440;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;peptidyl-tyrosine phosphorylation#GO:0018108;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;leukocyte activation#GO:0045321;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;lymphocyte activation involved in immune response#GO:0002285;regulation of multicellular organismal process#GO:0051239;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;programmed cell death#GO:0012501;cellular response to DNA damage stimulus#GO:0006974;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell activation#GO:0001775;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;regulation of protein phosphorylation#GO:0001932;type 2 immune response#GO:0042092;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;T cell activation involved in immune response#GO:0002286;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of intrinsic apoptotic signaling pathway#GO:2001242;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;signal transduction by p53 class mediator#GO:0072331;cytokine production#GO:0001816;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of transferase activity#GO:0051347;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;regulation of immune system process#GO:0002682;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;immune effector process#GO:0002252;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;negative regulation of response to stimulus#GO:0048585;positive regulation of catalytic activity#GO:0043085;immune response#GO:0006955;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of immune system process#GO:0002684;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;regulation of cell death#GO:0010941;positive regulation of kinase activity#GO:0033674;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;negative regulation of response to DNA damage stimulus#GO:2001021;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;antigen processing and presentation#GO:0019882;regulation of intracellular signal transduction#GO:1902531;regulation of phosphorus metabolic process#GO:0051174;positive regulation of immune response#GO:0050778;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;positive regulation of immune effector process#GO:0002699;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of production of molecular mediator of immune response#GO:0002700;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;peptidyl-amino acid modification#GO:0018193;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;signal transduction in response to DNA damage#GO:0042770;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;ERK1 and ERK2 cascade#GO:0070371;regulation of apoptotic process#GO:0042981;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;T cell activation#GO:0042110;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;cell surface#GO:0009986;protein-containing complex#GO:0032991;intracellular#GO:0005622;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 T cell activation#P00053>MHC-antigen#P01316 HUMAN|HGNC=2467|UniProtKB=O95196 O95196 CSPG5 PTHR15381:SF1 CHONDROITIN SULFATE PROTEOGLYCAN 5 -RELATED CHONDROITIN SULFATE PROTEOGLYCAN 5 HUMAN|HGNC=3491|UniProtKB=O00321 O00321 ETV2 PTHR11849:SF206 ETS ETS TRANSLOCATION VARIANT 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=19094|UniProtKB=Q96RQ9 Q96RQ9 IL4I1 PTHR10742:SF21 FLAVIN MONOAMINE OXIDASE L-AMINO-ACID OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 oxidase#PC00175 5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 HUMAN|HGNC=23198|UniProtKB=Q6ZWL3 Q6ZWL3 CYP4V2 PTHR24291:SF172 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177 HUMAN|HGNC=30081|UniProtKB=O95707 O95707 POP4 PTHR13348:SF0 RIBONUCLEASE P SUBUNIT P29 RIBONUCLEASE P PROTEIN SUBUNIT P29 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endoribonuclease activity#GO:0004521;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 small nucleolar ribonucleoprotein complex#GO:0005732;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172;ribonuclease P complex#GO:0030677;intracellular#GO:0005622;catalytic complex#GO:1902494 HUMAN|HGNC=7584|UniProtKB=P08590 P08590 MYL3 PTHR23048:SF2 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 3 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=667|UniProtKB=P61586 P61586 RHOA PTHR24072:SF153 RHO FAMILY GTPASE TRANSFORMING PROTEIN RHOA GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;stress fiber assembly#GO:0043149;contractile actin filament bundle assembly#GO:0030038;actin filament bundle assembly#GO:0051017;localization of cell#GO:0051674;cell motility#GO:0048870;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell division site#GO:0032153;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane#GO:0005886 small GTPase#PC00208 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;CCKR signaling map#P06959>RHOA-GTP#P07188;Axon guidance mediated by semaphorins#P00007>Rho#P00341;CCKR signaling map#P06959>RHOA-GDP#P07019;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Ras Pathway#P04393>Rho#P04578;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254 HUMAN|HGNC=14456|UniProtKB=Q9BTM1 Q9BTM1 H2AJ PTHR23430:SF59 HISTONE H2A HISTONE H2A.J heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=6502|UniProtKB=P08865 P08865 RPSA PTHR11489:SF17 40S RIBOSOMAL PROTEIN SA 40S RIBOSOMAL PROTEIN SA structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;ribosomal small subunit biogenesis#GO:0042274;cellular amide metabolic process#GO:0043603 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;90S preribosome#GO:0030686 ribosomal protein#PC00202 HUMAN|HGNC=24882|UniProtKB=Q9H4A5 Q9H4A5 GOLPH3L PTHR12704:SF4 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3-LIKE lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;Golgi vesicle budding#GO:0048194;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein localization to plasma membrane#GO:0072659;vesicle-mediated transport to the plasma membrane#GO:0098876;Golgi organization#GO:0007030;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031 trans-Golgi network#GO:0005802;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=6884|UniProtKB=Q9UPT6 Q9UPT6 MAPK8IP3 PTHR13886:SF3 JNK/SAPK-ASSOCIATED PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 3 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;transport#GO:0006810;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of JNK cascade#GO:0046330;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;positive regulation of protein serine/threonine kinase activity#GO:0071902;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11480|UniProtKB=O95425 O95425 SVIL PTHR11977:SF45 VILLIN SUPERVILLIN cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=28494|UniProtKB=Q8TC94 Q8TC94 ACTL9 PTHR11937:SF194 ACTIN ACTIN-LIKE PROTEIN 9 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;enzyme binding#GO:0019899;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein kinase binding#GO:0019901;kinase binding#GO:0019900 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;localization of cell#GO:0051674;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;organelle organization#GO:0006996;chromosome organization#GO:0051276;ATP-dependent chromatin remodeling#GO:0043044;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;chromatin organization#GO:0006325;generation of neurons#GO:0048699;chromatin remodeling#GO:0006338;locomotion#GO:0040011 synapse#GO:0045202;histone acetyltransferase complex#GO:0000123;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell junction#GO:0030054;intracellular organelle lumen#GO:0070013;cell periphery#GO:0071944;membrane#GO:0016020;nuclear chromatin#GO:0000790;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;plasma membrane#GO:0005886 actin and actin related protein#PC00039 HUMAN|HGNC=24452|UniProtKB=Q8IU60 Q8IU60 DCP2 PTHR23114:SF17 M7GPPPN-MRNA HYDROLASE M7GPPPN-MRNA HYDROLASE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=5825|UniProtKB=A0A0C4DH25 A0A0C4DH25 IGKV3D-20 PTHR23267:SF472 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-20-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=12449|UniProtKB=O43914 O43914 TYROBP PTHR17554:SF2 TYRO PROTEIN TYROSINE KINASE-BINDING PROTEIN TYRO PROTEIN TYROSINE KINASE-BINDING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;plasma membrane fusion#GO:0045026;regulation of protein metabolic process#GO:0051246;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;positive regulation of immune effector process#GO:0002699;B cell activation#GO:0042113;positive regulation of cytokine production#GO:0001819;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;negative regulation of leukocyte activation#GO:0002695;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;leukocyte activation involved in immune response#GO:0002366;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of cytokine biosynthetic process#GO:0042035;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;tumor necrosis factor production#GO:0032640;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;biosynthetic process#GO:0009058;cytokine production#GO:0001816;inflammatory response#GO:0006954;negative regulation of multicellular organismal process#GO:0051241;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;syncytium formation#GO:0006949;regulation of biosynthetic process#GO:0009889;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;immune effector process#GO:0002252;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;macromolecule biosynthetic process#GO:0009059;lymphocyte activation#GO:0046649;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular biosynthetic process#GO:0044249;lymphocyte proliferation#GO:0046651;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cell-cell fusion#GO:0140253;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of developmental process#GO:0051094;negative regulation of cell activation#GO:0050866;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;regulation of immune effector process#GO:0002697;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;syncytium formation by plasma membrane fusion#GO:0000768;regulation of leukocyte activation#GO:0002694;membrane fusion#GO:0061025;regulation of cellular biosynthetic process#GO:0031326;regulation of mononuclear cell proliferation#GO:0032944;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of cellular component organization#GO:0051130;regulation of lymphocyte proliferation#GO:0050670;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;regulation of B cell proliferation#GO:0030888 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 scaffold/adaptor protein#PC00226 HUMAN|HGNC=1368|UniProtKB=P00915 P00915 CA1 PTHR18952:SF82 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 1 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=24382|UniProtKB=Q7Z4L0 Q7Z4L0 COX8C PTHR16717:SF2 CYTOCHROME C OXIDASE POLYPEPTIDE VIII CYTOCHROME C OXIDASE SUBUNIT 8C, MITOCHONDRIAL cytoplasm#GO:0005737;respirasome#GO:0070469;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytochrome complex#GO:0070069;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidase#PC00175 HUMAN|HGNC=15654|UniProtKB=Q96SQ9 Q96SQ9 CYP2S1 PTHR24300:SF23 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2S1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=20323|UniProtKB=Q9H3U7 Q9H3U7 SMOC2 PTHR12352:SF21 SECRETED MODULAR CALCIUM-BINDING PROTEIN SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 2 heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;extracellular matrix binding#GO:0050840;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;basement membrane#GO:0005604;extracellular region#GO:0005576 calmodulin-related#PC00061 HUMAN|HGNC=29393|UniProtKB=Q96Q06 Q96Q06 PLIN4 PTHR47538:SF1 PERILIPIN 4 PERILIPIN-4 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=1691|UniProtKB=P30203 P30203 CD6 PTHR19331:SF400 SCAVENGER RECEPTOR DOMAIN-CONTAINING T-CELL DIFFERENTIATION ANTIGEN CD6 serine protease#PC00203 HUMAN|HGNC=1991|UniProtKB=P12277 P12277 CKB PTHR11547:SF23 ARGININE OR CREATINE KINASE CREATINE KINASE B-TYPE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 amino acid kinase#PC00045 HUMAN|HGNC=26097|UniProtKB=A5D8V6 A5D8V6 VPS37C PTHR13678:SF8 WILLIAMS-BEUREN SYNDROME CRITICAL REGION PROTEIN-RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37C protein catabolic process in the vacuole#GO:0007039;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;multivesicular body sorting pathway#GO:0071985;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;cellular protein catabolic process#GO:0044257;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=344|UniProtKB=O43865 O43865 AHCYL1 PTHR23420:SF3 ADENOSYLHOMOCYSTEINASE S-ADENOSYLHOMOCYSTEINE HYDROLASE-LIKE PROTEIN 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 HUMAN|HGNC=31043|UniProtKB=P0C7Q5 P0C7Q5 SLC35G4 PTHR22911:SF32 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G3-RELATED intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=25997|UniProtKB=Q53TQ3 Q53TQ3 INO80D PTHR16198:SF2 UNCHARACTERIZED INO80 COMPLEX SUBUNIT D HUMAN|HGNC=10026|UniProtKB=P04808 P04808 RLN1 PTHR12004:SF14 RELAXIN PRORELAXIN H1 peptide hormone#PC00179 HUMAN|HGNC=4118|UniProtKB=P51570 P51570 GALK1 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 carbohydrate kinase#PC00065 Fructose galactose metabolism#P02744>Galactokinase#P02960 HUMAN|HGNC=29163|UniProtKB=Q9Y2I6 Q9Y2I6 NINL PTHR18905:SF12 NINEIN NINEIN-LIKE PROTEIN cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;microtubule anchoring#GO:0034453;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 PDGF signaling pathway#P00047>GSK3#P01153 HUMAN|HGNC=19079|UniProtKB=Q9UF11 Q9UF11 PLEKHB1 PTHR14309:SF7 EXPRESSED PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY B MEMBER 1 regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=26172|UniProtKB=Q9H6K5 Q9H6K5 PRR36 PTHR22427:SF8 UNCHARACTERIZED PROLINE-RICH PROTEIN 36 HUMAN|HGNC=535|UniProtKB=P50995 P50995 ANXA11 PTHR10502:SF29 ANNEXIN ANNEXIN A11 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cell division#GO:0051301;membrane fission#GO:0090148;establishment of localization#GO:0051234;membrane organization#GO:0061024;phagocytosis#GO:0006909;transport#GO:0006810;cell cycle process#GO:0022402;cell cycle#GO:0007049;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;cytokinesis#GO:0000910 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calcium-binding protein#PC00060 HUMAN|HGNC=29556|UniProtKB=Q9BUP0 Q9BUP0 EFHD1 PTHR13025:SF5 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN D1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 calmodulin-related#PC00061 HUMAN|HGNC=29161|UniProtKB=Q9Y2H8 Q9Y2H8 ZNF510 PTHR24392:SF21 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 510 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1934|UniProtKB=Q5VXU3 Q5VXU3 CHIC1 PTHR13005:SF2 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN CYSTEINE-RICH HYDROPHOBIC DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=12347|UniProtKB=Q9Y4A5 Q9Y4A5 TRRAP PTHR11139:SF117 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED TRANSFORMATION/TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear lumen#GO:0031981 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=8241|UniProtKB=P58173 P58173 OR2B6 PTHR26453:SF202 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2B6 transmembrane signal receptor#PC00197 HUMAN|HGNC=29197|UniProtKB=Q9H7U1 Q9H7U1 CCSER2 PTHR22461:SF2 UNCHARACTERIZED SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=7197|UniProtKB=Q16653 Q16653 MOG PTHR24100:SF71 BUTYROPHILIN MYELIN-OLIGODENDROCYTE GLYCOPROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=30182|UniProtKB=Q9BYX7 Q9BYX7 POTEKP PTHR11937:SF278 ACTIN BETA-ACTIN-LIKE PROTEIN 3-RELATED actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Actin#P00944;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 HUMAN|HGNC=30032|UniProtKB=Q6VY07 Q6VY07 PACS1 PTHR13280:SF16 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 1 ion channel binding#GO:0044325;protein binding#GO:0005515;binding#GO:0005488 protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 HUMAN|HGNC=3260|UniProtKB=Q9UI10 Q9UI10 EIF2B4 PTHR10233:SF14 TRANSLATION INITIATION FACTOR EIF-2B TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA translation initiation factor#PC00224 HUMAN|HGNC=23694|UniProtKB=Q8N6U8 Q8N6U8 GPR161 PTHR22752:SF10 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 161 G-protein coupled receptor#PC00021 HUMAN|HGNC=27067|UniProtKB=Q32P51 Q32P51 HNRNPA1L2 PTHR48026:SF2 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1-RELATED HUMAN|HGNC=15943|UniProtKB=Q9NPB6 Q9NPB6 PARD6A PTHR14102:SF9 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG ALPHA Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;kinase binding#GO:0019900 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of localization#GO:0032879;cellular component organization#GO:0016043;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;regulation of biological process#GO:0050789;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 tight junction#PC00214 HUMAN|HGNC=25108|UniProtKB=Q7Z340 Q7Z340 ZNF551 PTHR24377:SF716 IP01015P-RELATED ZINC FINGER PROTEIN 551 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19880|UniProtKB=Q9Y6C2 Q9Y6C2 EMILIN1 PTHR15427:SF1 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-1 HUMAN|HGNC=16910|UniProtKB=Q9Y646 Q9Y646 CPQ PTHR12053:SF3 PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED CARBOXYPEPTIDASE Q metalloprotease#PC00153 HUMAN|HGNC=24260|UniProtKB=Q9Y3C7 Q9Y3C7 MED31 PTHR13186:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=24656|UniProtKB=Q9UBQ5 Q9UBQ5 EIF3K PTHR13022:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=7028|UniProtKB=Q5EB52 Q5EB52 MEST PTHR43139:SF43 SI:DKEY-122A22.2 MESODERM-SPECIFIC TRANSCRIPT HOMOLOG PROTEIN localization#GO:0051179;regulation of biological process#GO:0050789;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;maintenance of location#GO:0051235;biological regulation#GO:0065007;regulation of localization#GO:0032879;lipid localization#GO:0010876;lipid storage#GO:0019915 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=4977|UniProtKB=Q16534 Q16534 HLF PTHR11988:SF28 THYROTROPH EMBRYONIC FACTOR RELATED HEPATIC LEUKEMIA FACTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=17256|UniProtKB=Q9P1U1 Q9P1U1 ACTR3B PTHR11937:SF514 ACTIN ACTIN-RELATED PROTEIN 3B-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cortical cytoskeleton#GO:0030863;Arp2/3 protein complex#GO:0005885;cortical actin cytoskeleton#GO:0030864;actin cortical patch#GO:0030479;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 HUMAN|HGNC=29381|UniProtKB=Q9BRK4 Q9BRK4 LZTS2 PTHR19354:SF4 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 2-RELATED cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178;canonical Wnt signaling pathway#GO:0060070;negative regulation of cell communication#GO:0010648;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 HUMAN|HGNC=7579|UniProtKB=P35579 P35579 MYH9 PTHR45615:SF16 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-9 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=9359|UniProtKB=P58743 P58743 SLC26A5 PTHR11814:SF32 SULFATE TRANSPORTER PRESTIN inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;inorganic anion transmembrane transporter activity#GO:0015103;active ion transmembrane transporter activity#GO:0022853 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=24142|UniProtKB=Q9BX74 Q9BX74 TM2D1 PTHR21016:SF1 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=10977|UniProtKB=Q9HC58 Q9HC58 SLC24A3 PTHR10846:SF42 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM/POTASSIUM/CALCIUM EXCHANGER 3 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;cation:cation antiporter activity#GO:0015491;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;solute:cation antiporter activity#GO:0015298;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=7699|UniProtKB=O95168 O95168 NDUFB4 PTHR15469:SF1 NADH-UBIQUINONE OXIDOREDUCTASE B15 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 4 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=3612|UniProtKB=P06734 P06734 FCER2 PTHR22802:SF325 C-TYPE LECTIN SUPERFAMILY MEMBER LOW AFFINITY IMMUNOGLOBULIN EPSILON FC RECEPTOR membrane traffic protein#PC00150 HUMAN|HGNC=29017|UniProtKB=Q9Y4G2 Q9Y4G2 PLEKHM1 PTHR12326:SF5 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 1 HUMAN|HGNC=11511|UniProtKB=Q9BQG1 Q9BQG1 SYT3 PTHR10024:SF176 SYNAPTOTAGMIN SYNAPTOTAGMIN-3 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;syntaxin binding#GO:0019905;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cation transport#GO:0006812;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;response to metal ion#GO:0010038;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of ion transport#GO:0043269;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 HUMAN|HGNC=2937|UniProtKB=Q9Y485 Q9Y485 DMXL1 PTHR13950:SF12 RABCONNECTIN-RELATED DMX-LIKE PROTEIN 1 pH reduction#GO:0045851;regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;vacuolar acidification#GO:0007035;regulation of cellular pH#GO:0030641 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=5119|UniProtKB=P17481 P17481 HOXB8 PTHR46166:SF2 HOMEOBOX DOMAIN-CONTAINING PROTEIN HOMEOBOX PROTEIN HOX-B8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18592|UniProtKB=Q6ZWH5 Q6ZWH5 NEK10 PTHR43671:SF13 SERINE/THREONINE-PROTEIN KINASE NEK SERINE/THREONINE-PROTEIN KINASE NEK10-RELATED non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=33814|UniProtKB=Q5TCS8 Q5TCS8 AK9 PTHR23359:SF148 NUCLEOTIDE KINASE ADENYLATE KINASE 9 transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;adenylate kinase activity#GO:0004017;kinase activity#GO:0016301 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;purine ribonucleoside monophosphate metabolic process#GO:0009167;purine nucleoside diphosphate metabolic process#GO:0009135;ATP biosynthetic process#GO:0006754;purine nucleotide biosynthetic process#GO:0006164;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside monophosphate metabolic process#GO:0009126;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;nucleotide phosphorylation#GO:0046939;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;ADP metabolic process#GO:0046031;AMP metabolic process#GO:0046033;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide biosynthetic process#GO:0009152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotide kinase#PC00172 HUMAN|HGNC=26315|UniProtKB=Q76KP1 Q76KP1 B4GALNT4 PTHR12369:SF5 CHONDROITIN SYNTHASE N-ACETYL-BETA-GLUCOSAMINYL-GLYCOPROTEIN 4-BETA-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 HUMAN|HGNC=1130|UniProtKB=P62324 P62324 BTG1 PTHR22978:SF30 B-CELL TRANSLOCATION GENE PROTEIN BTG1 negative regulation of biological process#GO:0048519;regulation of cell population proliferation#GO:0042127;negative regulation of cell cycle#GO:0045786;nuclear division#GO:0000280;cell cycle process#GO:0022402;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular process#GO:0009987;cell population proliferation#GO:0008283;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;negative regulation of cell population proliferation#GO:0008285;regulation of mitotic cell cycle#GO:0007346;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9870|UniProtKB=P54136 P54136 RARS1 PTHR11956:SF5 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=28917|UniProtKB=Q86VZ6 Q86VZ6 JAZF1 PTHR23057:SF0 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=14346|UniProtKB=Q9BXJ3 Q9BXJ3 C1QTNF4 PTHR22923:SF107 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 4 HUMAN|HGNC=30132|UniProtKB=Q6TCH4 Q6TCH4 PAQR6 PTHR20855:SF39 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR DELTA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021 HUMAN|HGNC=11984|UniProtKB=Q6ZVM7 Q6ZVM7 TOM1L2 PTHR13856:SF31 VHS DOMAIN CONTAINING PROTEIN FAMILY TOM1-LIKE PROTEIN 2 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=8001|UniProtKB=P48552 P48552 NRIP1 PTHR15088:SF0 NUCLEAR FACTOR RIP140 NUCLEAR RECEPTOR-INTERACTING PROTEIN 1 HUMAN|HGNC=14134|UniProtKB=Q9NRR2 Q9NRR2 TPSG1 PTHR24256:SF487 TRYPTASE-RELATED TRYPTASE GAMMA serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=12843|UniProtKB=Q96TA2 Q96TA2 YME1L1 PTHR23076:SF97 METALLOPROTEASE M41 FTSH ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;peptidase activity#GO:0008233;nucleoside-triphosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;ATPase activity#GO:0016887 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metalloprotease#PC00153 HUMAN|HGNC=2675|UniProtKB=Q9UIK4 Q9UIK4 DAPK2 PTHR24342:SF15 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;intracellular signal transduction#GO:0035556;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=24477|UniProtKB=Q9NQZ2 Q9NQZ2 UTP3 PTHR13237:SF8 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED SOMETHING ABOUT SILENCING PROTEIN 10 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=3554|UniProtKB=Q92506 Q92506 HSD17B8 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER ESTRADIOL 17-BETA-DEHYDROGENASE 8 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidation-reduction process#GO:0055114;metabolic process#GO:0008152 oxidoreductase#PC00176 HUMAN|HGNC=9067|UniProtKB=Q13393 Q13393 PLD1 PTHR18896:SF57 PHOSPHOLIPASE D PHOSPHOLIPASE D1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;localization of cell#GO:0051674;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011 phospholipase#PC00186 Ras Pathway#P04393>PLD#P04574;Angiogenesis#P00005>PLD#P00204 HUMAN|HGNC=2208|UniProtKB=Q14031 Q14031 COL4A6 PTHR24023:SF533 COLLAGEN ALPHA COLLAGEN ALPHA-6(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;basement membrane#GO:0005604;extracellular region#GO:0005576;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;supramolecular polymer#GO:0099081 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=25286|UniProtKB=Q8TC99 Q8TC99 FNDC8 PTHR32430:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 8 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 8 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=4013|UniProtKB=Q10981 Q10981 FUT2 PTHR11927:SF2 GALACTOSIDE 2-L-FUCOSYLTRANSFERASE GALACTOSIDE ALPHA-(1,2)-FUCOSYLTRANSFERASE 2 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 glycosyltransferase#PC00111 HUMAN|HGNC=24432|UniProtKB=P82979 P82979 SARNP PTHR46551:SF2 SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=3074|UniProtKB=Q13202 Q13202 DUSP8 PTHR10159:SF108 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 8 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=8153|UniProtKB=P41143 P41143 OPRD1 PTHR24229:SF2 NEUROPEPTIDES RECEPTOR DELTA-TYPE OPIOID RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Enkephalin release#P05913>GPCR (i)#P05973;Opioid proopiomelanocortin pathway#P05917>Mu or Delta receptor#P06004;Opioid proenkephalin pathway#P05915>Mu or Delta receptor#P05985 HUMAN|HGNC=28658|UniProtKB=Q6DCA0 Q6DCA0 AMMECR1L PTHR13016:SF1 AMMECR1 HOMOLOG AMMECR1-LIKE PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=25749|UniProtKB=Q9C0B7 Q9C0B7 TANGO6 PTHR20959:SF1 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;peptide secretion#GO:0002790;cellular process#GO:0009987;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 HUMAN|HGNC=26518|UniProtKB=Q6GTS8 Q6GTS8 PM20D1 PTHR45962:SF1 N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D1 N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D1 nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152 hydrolase#PC00121 HUMAN|HGNC=23485|UniProtKB=Q8TE76 Q8TE76 MORC4 PTHR23336:SF22 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 4 HUMAN|HGNC=28371|UniProtKB=Q8N609 Q8N609 TRAM1L1 PTHR12371:SF9 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN 1-LIKE 1 cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=23458|UniProtKB=Q86XJ0 Q86XJ0 CALHM3 PTHR32261:SF7 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=19338|UniProtKB=Q9BWU1 Q9BWU1 CDK19 PTHR24056:SF131 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 19 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cytosol#GO:0005829;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;nuclear lumen#GO:0031981 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=26422|UniProtKB=Q96NG5 Q96NG5 ZNF558 PTHR24381:SF80 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 558 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26277|UniProtKB=Q6P589 Q6P589 TNFAIP8L2 PTHR12757:SF4 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=37636|UniProtKB=Q3C1V0 Q3C1V0 MS4A18 PTHR23320:SF37 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 18 transporter#PC00227 HUMAN|HGNC=16233|UniProtKB=Q9H4G1 Q9H4G1 CST9L PTHR46945:SF1 CYSTATIN-9-LIKE CYSTATIN-9-LIKE response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=53111|UniProtKB=P86397 P86397 HTD2 PTHR43437:SF3 HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED dehydratase#PC00091 HUMAN|HGNC=13838|UniProtKB=Q86SQ6 Q86SQ6 ADGRA1 PTHR45930:SF3 G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN ADHESION G PROTEIN-COUPLED RECEPTOR A1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;organelle#GO:0043226;asymmetric synapse#GO:0032279;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=6862|UniProtKB=P27816 P27816 MAP4 PTHR11501:SF16 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;neuron development#GO:0048666;generation of neurons#GO:0048699 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=13098|UniProtKB=Q8IZ26 Q8IZ26 ZNF34 PTHR24377:SF818 IP01015P-RELATED ZINC FINGER PROTEIN 34 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=9883|UniProtKB=P50749 P50749 RASSF2 PTHR22738:SF14 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18196|UniProtKB=Q9BT81 Q9BT81 SOX7 PTHR10270:SF210 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=12477|UniProtKB=P51965 P51965 UBE2E1 PTHR24068:SF70 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=34531|UniProtKB=A6NFE3 A6NFE3 EFCAB10 PTHR21847:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 calmodulin-related#PC00061 HUMAN|HGNC=29058|UniProtKB=O60268 O60268 KIAA0513 PTHR13663:SF2 UNCHARACTERIZED SIMILAR TO RIKEN CDNA 6430548M08 HUMAN|HGNC=13516|UniProtKB=Q9NR09 Q9NR09 BIRC6 PTHR46116:SF12 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 6 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 HUMAN|HGNC=4461|UniProtKB=Q13491 Q13491 GPM6B PTHR11683:SF10 MYELIN PROTEOLIPID NEURONAL MEMBRANE GLYCOPROTEIN M6-B organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;cell projection organization#GO:0030030;transport#GO:0006810;developmental process#GO:0032502;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;cation transport#GO:0006812;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;system development#GO:0048731;cell differentiation#GO:0030154;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter transport#GO:0006836;neuron differentiation#GO:0030182;negative regulation of cellular process#GO:0048523;cellular developmental process#GO:0048869;ion transport#GO:0006811;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;negative regulation of transport#GO:0051051;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;organic cation transport#GO:0015695;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;neuron development#GO:0048666;regulation of ion transport#GO:0043269;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857;membrane region#GO:0098589;whole membrane#GO:0098805;plasma membrane#GO:0005886 myelin protein#PC00161 HUMAN|HGNC=26292|UniProtKB=A1L3X0 A1L3X0 ELOVL7 PTHR11157:SF118 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 7 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=6852|UniProtKB=O43283 O43283 MAP3K13 PTHR44329:SF14 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 13 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;positive regulation of DNA-binding transcription factor activity#GO:0051091;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 HUMAN|HGNC=9154|UniProtKB=Q96T60 Q96T60 PNKP PTHR12083:SF9 BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE HUMAN|HGNC=9189|UniProtKB=P19387 P19387 POLR2C PTHR11800:SF2 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 HUMAN|HGNC=2492|UniProtKB=O75638 O75638 CTAG2 PTHR31283:SF15 EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER CANCER/TESTIS ANTIGEN 2 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;tRNA threonylcarbamoyladenosine metabolic process#GO:0070525;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;EKC/KEOPS complex#GO:0000408;intracellular#GO:0005622 HUMAN|HGNC=16687|UniProtKB=Q9NRA8 Q9NRA8 EIF4ENIF1 PTHR12269:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=5133|UniProtKB=P28358 P28358 HOXD10 PTHR45874:SF5 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-D10 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=24090|UniProtKB=Q6UW56 Q6UW56 ATRAID PTHR15926:SF1 ALL-TRANS RETINOIC ACID-INDUCED DIFFERENTIATION FACTOR ALL-TRANS RETINOIC ACID-INDUCED DIFFERENTIATION FACTOR HUMAN|HGNC=5241|UniProtKB=P11142 P11142 HSPA8 PTHR19375:SF379 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524;ATPase activity#GO:0016887 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;chaperone-mediated protein folding#GO:0061077;cellular response to organic substance#GO:0071310;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;localization#GO:0051179;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;establishment of localization#GO:0051234;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;'de novo' protein folding#GO:0006458;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 HUMAN|HGNC=24324|UniProtKB=Q8WX92 Q8WX92 NELFB PTHR13503:SF3 NEGATIVE ELONGATION FACTOR COMPLEX MEMBER B NEGATIVE ELONGATION FACTOR B HUMAN|HGNC=18910|UniProtKB=Q9BYQ8 Q9BYQ8 KRTAP4-9 PTHR23262:SF203 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-9 HUMAN|HGNC=6273|UniProtKB=P57789 P57789 KCNK10 PTHR11003:SF32 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 10 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=14362|UniProtKB=Q7Z5P9 Q7Z5P9 MUC19 PTHR47246:SF1 MUCIN-19 MUCIN-19 HUMAN|HGNC=24539|UniProtKB=Q8NC96 Q8NC96 NECAP1 PTHR12847:SF15 ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED ADAPTIN EAR-BINDING COAT-ASSOCIATED PROTEIN 1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;vesicle coat#GO:0030120;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;protein-containing complex#GO:0032991;membrane coat#GO:0030117;intracellular#GO:0005622;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=487|UniProtKB=Q9Y264 Q9Y264 ANGPT4 PTHR19143:SF31 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-4 system development#GO:0048731;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;blood vessel development#GO:0001568;vasculature development#GO:0001944;multicellular organismal process#GO:0032501;anatomical structure formation involved in morphogenesis#GO:0048646 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=2938|UniProtKB=Q8TDJ6 Q8TDJ6 DMXL2 PTHR13950:SF13 RABCONNECTIN-RELATED DMX-LIKE PROTEIN 2 pH reduction#GO:0045851;regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;vacuolar acidification#GO:0007035;regulation of cellular pH#GO:0030641 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=25789|UniProtKB=Q7Z2Z2 Q7Z2Z2 EFL1 PTHR42908:SF3 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR-LIKE GTPASE 1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 translation elongation factor#PC00222 HUMAN|HGNC=24476|UniProtKB=Q9Y2H0 Q9Y2H0 DLGAP4 PTHR12353:SF19 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 4 molecular adaptor activity#GO:0060090;binding#GO:0005488 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;regulation of neurotransmitter receptor activity#GO:0099601;chemical synaptic transmission, postsynaptic#GO:0099565;system process#GO:0003008;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;regulation of system process#GO:0044057;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;signaling#GO:0023052 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;postsynapse#GO:0098794;synapse#GO:0045202;postsynaptic specialization#GO:0099572;cellular anatomical entity#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 HUMAN|HGNC=24581|UniProtKB=Q6Y2X3 Q6Y2X3 DNAJC14 PTHR44665:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 14 DNAJ HOMOLOG SUBFAMILY C MEMBER 14 chaperone#PC00072 HUMAN|HGNC=26077|UniProtKB=Q8TCQ1 Q8TCQ1 MARCHF1 PTHR45981:SF1 LD02310P E3 UBIQUITIN-PROTEIN LIGASE MARCHF1 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;MHC protein binding#GO:0042287;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;immune response#GO:0006955;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;antigen processing and presentation#GO:0019882;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;immune system process#GO:0002376;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;late endosome membrane#GO:0031902;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=10371|UniProtKB=P05388 P05388 RPLP0 PTHR45699:SF1 60S ACIDIC RIBOSOMAL PROTEIN P0 60S ACIDIC RIBOSOMAL PROTEIN P0-RELATED structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=17187|UniProtKB=Q99784 Q99784 OLFM1 PTHR23192:SF34 OLFACTOMEDIN-RELATED NOELIN structural protein#PC00211 HUMAN|HGNC=16249|UniProtKB=Q9H3Y0 Q9H3Y0 R3HDML PTHR10334:SF62 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR R3HDML extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=9156|UniProtKB=P54315 P54315 PNLIPRP1 PTHR11610:SF108 LIPASE INACTIVE PANCREATIC LIPASE-RELATED PROTEIN 1 hydrolase activity#GO:0016787;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;lipid catabolic process#GO:0016042;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 lipase#PC00143 HUMAN|HGNC=23138|UniProtKB=Q9ULK6 Q9ULK6 RNF150 PTHR22765:SF42 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING FINGER PROTEIN 150 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=23145|UniProtKB=Q8NHW3 Q8NHW3 MAFA PTHR10129:SF30 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=18714|UniProtKB=Q9NPI6 Q9NPI6 DCP1A PTHR16290:SF4 TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 MRNA-DECAPPING ENZYME 1A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;enzyme regulator activity#GO:0030234 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;deadenylation-dependent decapping of nuclear-transcribed mRNA#GO:0000290;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 mRNA capping factor#PC00145 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 HUMAN|HGNC=30767|UniProtKB=Q9Y448 Q9Y448 KNSTRN PTHR31940:SF2 SMALL KINETOCHORE-ASSOCIATED PROTEIN SMALL KINETOCHORE-ASSOCIATED PROTEIN nuclear chromosome segregation#GO:0098813;regulation of chromosome segregation#GO:0051983;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;attachment of spindle microtubules to kinetochore#GO:0008608;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;spindle organization#GO:0007051;mitotic sister chromatid segregation#GO:0000070 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;kinetochore#GO:0000776;chromosome, centromeric region#GO:0000775;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;intracellular#GO:0005622;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 HUMAN|HGNC=7687|UniProtKB=O00483 O00483 NDUFA4 PTHR14256:SF4 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT CYTOCHROME C OXIDASE SUBUNIT NDUFA4 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277 oxidoreductase#PC00176 HUMAN|HGNC=4685|UniProtKB=Q02108 Q02108 GUCY1A1 PTHR45655:SF4 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT ALPHA-1 guanylate cyclase#PC00114 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 HUMAN|HGNC=15698|UniProtKB=Q7Z7E8 Q7Z7E8 UBE2Q1 PTHR24068:SF56 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 Q1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=15808|UniProtKB=Q9H116 Q9H116 GZF1 PTHR24384:SF191 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED GDNF-INDUCIBLE ZINC FINGER PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=27407|UniProtKB=Q147U7 Q147U7 SMCO1 PTHR35979:SF1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=7462|UniProtKB=P03923 P03923 MT-ND6 PTHR11435:SF1 NADH UBIQUINONE OXIDOREDUCTASE SUBUNIT ND6 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176 HUMAN|HGNC=7541|UniProtKB=P84157 P84157 MXRA7 PTHR21845:SF2 TRANSMEMBRANE ANCHOR PROTEIN 1 MATRIX-REMODELING-ASSOCIATED PROTEIN 7 HUMAN|HGNC=13588|UniProtKB=Q9UK97 Q9UK97 FBXO9 PTHR12874:SF9 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 9 HUMAN|HGNC=8718|UniProtKB=Q9Y5F6 Q9Y5F6 PCDHGC5 PTHR24028:SF258 CADHERIN-87A PROTOCADHERIN GAMMA-C5 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=26435|UniProtKB=Q96NB1 Q96NB1 CEP20 PTHR15431:SF4 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 20 HUMAN|HGNC=23953|UniProtKB=Q8N888 Q8N888 BCORP1 PTHR24117:SF8 AGAP007537-PB BCL-6 COREPRESSOR-RELATED HUMAN|HGNC=20599|UniProtKB=Q8WWU7 Q8WWU7 ITLN2 PTHR16146:SF21 INTELECTIN INTELECTIN-2 HUMAN|HGNC=9103|UniProtKB=O43157 O43157 PLXNB1 PTHR22625:SF36 PLEXIN PLEXIN-B1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of GTPase activity#GO:0043087;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of neuron differentiation#GO:0045664;negative regulation of cell adhesion#GO:0007162;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;positive regulation of neuron projection development#GO:0010976;locomotion#GO:0040011;taxis#GO:0042330;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of cell projection organization#GO:0031346;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;biological adhesion#GO:0022610;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of cell adhesion#GO:0030155;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;positive regulation of neuron differentiation#GO:0045666;cellular response to stimulus#GO:0051716;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;cell migration#GO:0016477 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 Axon guidance mediated by semaphorins#P00007>plexinB1#P00328 HUMAN|HGNC=2884|UniProtKB=Q92813 Q92813 DIO2 PTHR11781:SF20 IODOTHYRONINE DEIODINASE TYPE II IODOTHYRONINE DEIODINASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=3349|UniProtKB=P17813 P17813 ENG PTHR14002:SF1 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ENDOGLIN cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=23046|UniProtKB=Q5SYC1 Q5SYC1 CLVS2 PTHR10174:SF73 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CLAVESIN-2 phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 HUMAN|HGNC=24032|UniProtKB=Q5VVC0 Q5VVC0 C1orf146 PTHR31408:SF2 HYPOTHETICAL PROTEIN LOC689986 HYPOTHETICAL PROTEIN LOC689986 HUMAN|HGNC=4074|UniProtKB=Q06547 Q06547 GABPB1 PTHR24193:SF76 ANKYRIN REPEAT PROTEIN GA-BINDING PROTEIN SUBUNIT BETA-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4894|UniProtKB=Q04756 Q04756 HGFAC PTHR24264:SF43 TRYPSIN-RELATED HEPATOCYTE GROWTH FACTOR ACTIVATOR serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;regulation of body fluid levels#GO:0050878;wound healing#GO:0042060;hemostasis#GO:0007599;coagulation#GO:0050817;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=19905|UniProtKB=Q96PU9 Q96PU9 ODF3 PTHR21580:SF23 SHIPPO-1-RELATED OUTER DENSE FIBER PROTEIN 3 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;C2 axonemal microtubule#GO:1990720;B axonemal microtubule#GO:0097650;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;axonemal microtubule#GO:0005879 structural protein#PC00211 HUMAN|HGNC=23592|UniProtKB=Q6T311 Q6T311 ARL9 PTHR46724:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9 HUMAN|HGNC=32203|UniProtKB=Q5H8A3 Q5H8A3 NMS PTHR32414:SF2 NEUROMEDIN-S NEUROMEDIN-S HUMAN|HGNC=11717|UniProtKB=Q15561 Q15561 TEAD4 PTHR11834:SF2 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;hippo signaling#GO:0035329;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=14075|UniProtKB=Q96LD1 Q96LD1 SGCZ PTHR12939:SF5 SARCOGLYCAN ZETA-SARCOGLYCAN blood circulation#GO:0008015;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;heart contraction#GO:0060047;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;system process#GO:0003008;developmental process#GO:0032502;circulatory system process#GO:0003013;tissue development#GO:0009888;muscle tissue development#GO:0060537;system development#GO:0048731;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;heart process#GO:0003015 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;sarcolemma#GO:0042383 cytoskeletal protein#PC00085 HUMAN|HGNC=12577|UniProtKB=O00322 O00322 UPK1A PTHR19282:SF25 TETRASPANIN UROPLAKIN-1A response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=8191|UniProtKB=Q8WZA6 Q8WZA6 OR1E3 PTHR48001:SF130 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1E1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=25562|UniProtKB=Q3KR16 Q3KR16 PLEKHG6 PTHR47671:SF1 PLECKSTRIN DOMAIN-CONTAINING FAMILY G MEMBER 6 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 6 HUMAN|HGNC=25280|UniProtKB=Q96NG3 Q96NG3 TTC25 PTHR23040:SF1 UNCHARACTERIZED TETRATRICOPEPTIDE REPEAT PROTEIN 25 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=24725|UniProtKB=Q96PZ2 Q96PZ2 FAM111A PTHR14389:SF14 SI:CH1073-475A24.1 PROTEIN FAM111A HUMAN|HGNC=2324|UniProtKB=Q10570 Q10570 CPSF1 PTHR10644:SF2 DNA REPAIR/RNA PROCESSING CPSF FAMILY CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=16112|UniProtKB=A0PJX2 A0PJX2 TLDC2 PTHR23354:SF65 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED TLD DOMAIN-CONTAINING PROTEIN 2 cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of neuron death#GO:1901214;regulation of response to stress#GO:0080134;neuron death#GO:0070997;response to oxidative stress#GO:0006979;negative regulation of neuron death#GO:1901215;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;response to stimulus#GO:0050896;regulation of cellular response to stress#GO:0080135;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;negative regulation of cellular process#GO:0048523 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=34417|UniProtKB=Q09MP3 Q09MP3 RAD51AP2 PTHR15361:SF6 RAD51/NUKS-INTERACTING PROTEIN RAD51-ASSOCIATED PROTEIN 2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=26052|UniProtKB=Q5TA45 Q5TA45 INTS11 PTHR11203:SF37 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER INTEGRATOR COMPLEX SUBUNIT 11 RNA processing factor#PC00147 HUMAN|HGNC=18099|UniProtKB=Q8N690 Q8N690 DEFB119 PTHR47902:SF1 BETA-DEFENSIN 119 BETA-DEFENSIN 119 carbohydrate derivative binding#GO:0097367;lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;defense response to fungus#GO:0050832;defense response to Gram-positive bacterium#GO:0050830;defense response to Gram-negative bacterium#GO:0050829;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 antimicrobial response protein#PC00051 HUMAN|HGNC=51846|UniProtKB=Q8TCY0 Q8TCY0 SMIM11B PTHR35975:SF2 SMALL INTEGRAL MEMBRANE PROTEIN 11A SMALL INTEGRAL MEMBRANE PROTEIN 11B HUMAN|HGNC=23418|UniProtKB=Q5SRD0 Q5SRD0 WASHC2D PTHR21669:SF1 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS WASH COMPLEX SUBUNIT 2A-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=18038|UniProtKB=Q96A83 Q96A83 COL26A1 PTHR15427:SF19 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COLLAGEN ALPHA-1(XXVI) CHAIN HUMAN|HGNC=9261|UniProtKB=Q13356 Q13356 PPIL2 PTHR45625:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=11569|UniProtKB=Q15633 Q15633 TARBP2 PTHR46205:SF1 LOQUACIOUS, ISOFORM B RISC-LOADING COMPLEX SUBUNIT TARBP2 HUMAN|HGNC=24697|UniProtKB=Q96N46 Q96N46 TTC14 PTHR23184:SF9 TETRATRICOPEPTIDE REPEAT PROTEIN 14 TETRATRICOPEPTIDE REPEAT PROTEIN 14 HUMAN|Ensembl=ENSG00000284552|UniProtKB=A0A1W2PRN6 A0A1W2PRN6 LINC02218 PTHR13218:SF17 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TAFII28 DOMAIN-CONTAINING PROTEIN transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=15781|UniProtKB=Q494W8 Q494W8 CHRFAM7A PTHR18945:SF890 NEUROTRANSMITTER GATED ION CHANNEL CHRNA7-FAM7A FUSION PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=32403|UniProtKB=Q8NAA5 Q8NAA5 LRRC75A PTHR14224:SF42 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 75A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=5959|UniProtKB=O95163 O95163 ELP1 PTHR12747:SF0 ELONGATOR COMPLEX PROTEIN 1 ELONGATOR COMPLEX PROTEIN 1 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 general transcription factor#PC00259 PDGF signaling pathway#P00047>Ikk#P01146 HUMAN|HGNC=4497|UniProtKB=P46093 P46093 GPR4 PTHR24232:SF36 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=18412|UniProtKB=Q8IUH5 Q8IUH5 ZDHHC17 PTHR24161:SF18 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE ZDHHC17 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=3040|UniProtKB=P53805 P53805 RCAN1 PTHR10300:SF4 CALCIPRESSIN CALCIPRESSIN-1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;protein serine/threonine phosphatase activity#GO:0004722;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;regulation of signaling#GO:0023051;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 intercellular signal molecule#PC00207 HUMAN|HGNC=13009|UniProtKB=O75362 O75362 ZNF217 PTHR45925:SF4 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 217 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11976|UniProtKB=P22105 P22105 TNXB PTHR46708:SF3 TENASCIN TENASCIN-X-RELATED extracellular matrix protein#PC00102 HUMAN|Ensembl=ENSG00000285408|UniProtKB=A0A2R8YFR7 A0A2R8YFR7 ENSG00000285408 PTHR12845:SF2 GUANINE NUCLEOTIDE EXCHANGE FACTOR DH DOMAIN-CONTAINING PROTEIN-RELATED Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=16197|UniProtKB=Q96S44 Q96S44 TP53RK PTHR12209:SF0 O-SIALOGLYCOPROTEIN ENDOPEPTIDASE EKC/KEOPS COMPLEX SUBUNIT TP53RK transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 HUMAN|HGNC=28161|UniProtKB=Q9BV47 Q9BV47 DUSP26 PTHR45682:SF8 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 26 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=7664|UniProtKB=P16333 P16333 NCK1 PTHR19969:SF16 SH2-SH3 ADAPTOR PROTEIN-RELATED CYTOPLASMIC PROTEIN NCK1 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Nck#P00215;PDGF signaling pathway#P00047>Nck#P01147;PDGF signaling pathway#P00047>Grb2#P01148;T cell activation#P00053>nck#P01314 HUMAN|HGNC=26661|UniProtKB=Q8IYW5 Q8IYW5 RNF168 PTHR23328:SF1 UNCHARACTERIZED E3 UBIQUITIN-PROTEIN LIGASE RNF168 HUMAN|HGNC=13824|UniProtKB=Q96T76 Q96T76 MMS19 PTHR12891:SF0 DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19 MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=31815|UniProtKB=Q8IXL9 Q8IXL9 IQCF2 PTHR21633:SF4 IQ MOTIF CONTAINING F IQ DOMAIN-CONTAINING PROTEIN F2 protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 HUMAN|HGNC=8680|UniProtKB=Q9Y5F3 Q9Y5F3 PCDHB1 PTHR24028:SF12 CADHERIN-87A PROTOCADHERIN BETA-1 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=7778|UniProtKB=Q14934 Q14934 NFATC4 PTHR12533:SF11 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772 positive regulation of gene expression#GO:0010628;calcium-mediated signaling#GO:0019722;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252 Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Axon guidance mediated by netrin#P00009>NFAT#P00359;Wnt signaling pathway#P00057>NFAT#P01452;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367 HUMAN|HGNC=7661|UniProtKB=P19878 P19878 NCF2 PTHR15175:SF3 NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2 NEUTROPHIL CYTOSOL FACTOR 2 Ras GTPase binding#GO:0017016;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;Rac GTPase binding#GO:0048365;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;oxidoreductase activity#GO:0016491;enzyme regulator activity#GO:0030234 cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein-binding activity modulator#PC00095 HUMAN|HGNC=11968|UniProtKB=Q9BT09 Q9BT09 CNPY3 PTHR15382:SF2 CTG4A-RELATED PROTEIN CANOPY HOMOLOG 3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=19009|UniProtKB=Q96AJ1 Q96AJ1 CLUAP1 PTHR21547:SF0 CLUSTERIN ASSOCIATED PROTEIN 1 CLUSTERIN-ASSOCIATED PROTEIN 1 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=3960|UniProtKB=O14926 O14926 FSCN2 PTHR10551:SF24 FASCIN FASCIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament bundle assembly#GO:0051017;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=13847|UniProtKB=Q5JNZ3 Q5JNZ3 ZNF311 PTHR24377:SF273 IP01015P-RELATED ZINC FINGER PROTEIN 311 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24299|UniProtKB=Q5SWX8 Q5SWX8 ODR4 PTHR33966:SF1 PROTEIN ODR-4 HOMOLOG PROTEIN ODR-4 HOMOLOG localization#GO:0051179;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=29596|UniProtKB=Q3YBM2 Q3YBM2 TMEM176B PTHR15756:SF7 LR8/HCA112 TRANSMEMBRANE PROTEIN 176B cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;immune system development#GO:0002520;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;system development#GO:0048731;negative regulation of multicellular organismal process#GO:0051241;immune system process#GO:0002376;regulation of hemopoiesis#GO:1903706;leukocyte differentiation#GO:0002521;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;multicellular organismal process#GO:0032501;negative regulation of immune system process#GO:0002683;negative regulation of cellular process#GO:0048523 HUMAN|HGNC=12730|UniProtKB=Q9UGM6 Q9UGM6 WARS2 PTHR43766:SF1 TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=23713|UniProtKB=Q96IT1 Q96IT1 ZNF496 PTHR23226:SF180 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 496 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11806|UniProtKB=Q8IVF5 Q8IVF5 TIAM2 PTHR46001:SF5 TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG T-LYMPHOMA INVASION AND METASTASIS-INDUCING PROTEIN 2 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of GTPase activity#GO:0043087;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron differentiation#GO:0045664;positive regulation of hydrolase activity#GO:0051345;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;positive regulation of cell projection organization#GO:0031346;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;system development#GO:0048731;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;positive regulation of neuron differentiation#GO:0045666;cellular response to stimulus#GO:0051716;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=3383|UniProtKB=P27105 P27105 STOM PTHR10264:SF115 BAND 7 PROTEIN-RELATED ERYTHROCYTE BAND 7 INTEGRAL MEMBRANE PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=21151|UniProtKB=Q9BV68 Q9BV68 RNF126 PTHR15710:SF21 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF126 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=5759|UniProtKB=A0A087WSZ0 A0A087WSZ0 IGKV1D-8 PTHR23267:SF320 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=7234|UniProtKB=Q96E11 Q96E11 MRRF PTHR20982:SF10 RIBOSOME RECYCLING FACTOR RIBOSOME-RECYCLING FACTOR, MITOCHONDRIAL ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 translation release factor#PC00225 HUMAN|HGNC=20685|UniProtKB=Q8N271 Q8N271 PROM2 PTHR22730:SF6 PROMININ PROM PROTEIN PROMININ-2 lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;cholesterol binding#GO:0015485;steroid binding#GO:0005496;sterol binding#GO:0032934 supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;actin filament#GO:0005884;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;non-membrane-bounded organelle#GO:0043228;cell surface#GO:0009986;intrinsic component of membrane#GO:0031224;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microvillus#GO:0005902;extracellular region#GO:0005576;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=17382|UniProtKB=Q7Z6B7 Q7Z6B7 SRGAP1 PTHR14166:SF15 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 1 Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048 regulation of cellular component movement#GO:0051270;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;localization of cell#GO:0051674;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of cell motility#GO:2000146;cell migration#GO:0016477;locomotion#GO:0040011;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 Axon guidance mediated by Slit/Robo#P00008>SrGAP#P00350;PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=4198|UniProtKB=O75603 O75603 GCM2 PTHR12414:SF7 GLIAL CELLS MISSING RELATED/GLIDE CHORION-SPECIFIC TRANSCRIPTION FACTOR GCMB cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;gliogenesis#GO:0042063;cellular process#GO:0009987;nervous system development#GO:0007399 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=18020|UniProtKB=Q16378 Q16378 PRR4 PTHR23203:SF9 PROLINE-RICH PROTEIN PROLINE-RICH PROTEIN 4 antimicrobial response protein#PC00051 HUMAN|HGNC=10808|UniProtKB=O43556 O43556 SGCE PTHR10132:SF17 ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER EPSILON-SARCOGLYCAN membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 cadherin#PC00057 HUMAN|HGNC=22938|UniProtKB=P59046 P59046 NLRP12 PTHR45690:SF11 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 HUMAN|HGNC=20396|UniProtKB=Q9UKJ1 Q9UKJ1 PILRA PTHR15549:SF1 PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR ALPHA protein binding#GO:0005515;MHC protein binding#GO:0042287;binding#GO:0005488;signaling receptor binding#GO:0005102 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=24086|UniProtKB=Q9NQ94 Q9NQ94 A1CF PTHR21245:SF8 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN APOBEC1 COMPLEMENTATION FACTOR nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=5021|UniProtKB=P55317 P55317 FOXA1 PTHR11829:SF195 FORKHEAD BOX PROTEIN HEPATOCYTE NUCLEAR FACTOR 3-ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=24865|UniProtKB=Q9HCL2 Q9HCL2 GPAM PTHR12563:SF16 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;triglyceride metabolic process#GO:0006641;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;fatty acid metabolic process#GO:0006631;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=14880|UniProtKB=Q969Y2 Q969Y2 GTPBP3 PTHR42714:SF2 TRNA MODIFICATION GTPASE GTPBP3 TRNA MODIFICATION GTPASE GTPBP3, MITOCHONDRIAL cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA methyltransferase#PC00033 HUMAN|HGNC=3562|UniProtKB=O15540 O15540 FABP7 PTHR11955:SF57 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, BRAIN HUMAN|HGNC=19075|UniProtKB=Q96CG3 Q96CG3 TIFA PTHR31266:SF2 TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A FAMILY MEMBER TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A HUMAN|HGNC=2509|UniProtKB=P35221 P35221 CTNNA1 PTHR18914:SF24 ALPHA CATENIN CATENIN ALPHA-1 non-motor actin binding protein#PC00165 Alzheimer disease-presenilin pathway#P00004>alpha-catenin#P00133;Wnt signaling pathway#P00057>alpha-catenin#P01471;Cadherin signaling pathway#P00012>alpha-catenin#P00467 HUMAN|HGNC=6277|UniProtKB=O95069 O95069 KCNK2 PTHR11003:SF21 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=4817|UniProtKB=P49590 P49590 HARS2 PTHR11476:SF6 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE, MITOCHONDRIAL identical protein binding#GO:0042802;protein binding#GO:0005515;binding#GO:0005488 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=30456|UniProtKB=Q96DA0 Q96DA0 ZG16B PTHR33589:SF1 OS11G0524900 PROTEIN ZYMOGEN GRANULE PROTEIN 16 HOMOLOG B extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|Ensembl=ENSG00000283654|UniProtKB=A0A1B0GTW7 A0A1B0GTW7 LMLN2 PTHR10942:SF6 LEISHMANOLYSIN-LIKE PEPTIDASE LEISHMANOLYSIN-LIKE PEPTIDASE 2 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=18807|UniProtKB=O94983 O94983 CAMTA2 PTHR23335:SF9 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 2 nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=2319|UniProtKB=O95741 O95741 CPNE6 PTHR10857:SF5 COPINE COPINE-6 calcium-dependent phospholipid binding#GO:0005544;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;binding#GO:0005488 response to metal ion#GO:0010038;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=12614|UniProtKB=Q9Y5T5 Q9Y5T5 USP16 PTHR21646:SF12 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 16 cysteine protease#PC00081 HUMAN|HGNC=44452|UniProtKB=Q0WX57 Q0WX57 USP17L27 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=7504|UniProtKB=Q13505 Q13505 MTX1 PTHR12289:SF34 METAXIN RELATED METAXIN-1 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=30258|UniProtKB=Q9BRP8 Q9BRP8 PYM1 PTHR22959:SF0 PYM PROTEIN PARTNER OF Y14 AND MAGO nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29408|UniProtKB=B1AJZ9 B1AJZ9 FHAD1 PTHR18853:SF7 FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=31270|UniProtKB=A6NMZ5 A6NMZ5 OR4C45 PTHR48002:SF75 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C45 transmembrane signal receptor#PC00197 HUMAN|HGNC=6931|UniProtKB=P41968 P41968 MC3R PTHR22750:SF4 G-PROTEIN COUPLED RECEPTOR MELANOCORTIN RECEPTOR 3 signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=15196|UniProtKB=A6NGY5 A6NGY5 OR51F1 PTHR26450:SF46 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51F1 transmembrane signal receptor#PC00197 HUMAN|HGNC=6407|UniProtKB=P01116 P01116 KRAS PTHR24070:SF388 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE KRAS GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;FGF signaling pathway#P00021>Ras#P00633;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552;Angiogenesis#P00005>Ras#P00238;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;Ras Pathway#P04393>Ras#P04547;PI3 kinase pathway#P00048>Ras#P01182;p53 pathway feedback loops 2#P04398>Ras#P04651;Integrin signalling pathway#P00034>Ras#P00916;VEGF signaling pathway#P00056>Ras#P01411 HUMAN|HGNC=7414|UniProtKB=P00846 P00846 MT-ATP6 PTHR11410:SF0 ATP SYNTHASE SUBUNIT A ATP SYNTHASE SUBUNIT A ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide biosynthetic process#GO:0009152 membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;proton-transporting ATP synthase complex#GO:0045259;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular#GO:0005622 ATP synthase#PC00002 ATP synthesis#P02721>ATP synthetase F0#P02797 HUMAN|HGNC=343|UniProtKB=P23526 P23526 AHCY PTHR23420:SF20 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 HUMAN|HGNC=15200|UniProtKB=Q9H343 Q9H343 OR51I1 PTHR26450:SF66 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51I1 transmembrane signal receptor#PC00197 HUMAN|HGNC=4117|UniProtKB=Q00973 Q00973 B4GALNT1 PTHR15046:SF1 GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN BETA-1,4 N-ACETYLGALACTOSAMINYLTRANSFERASE 1 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound biosynthetic process#GO:1901566;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704 HUMAN|HGNC=2048|UniProtKB=P56747 P56747 CLDN6 PTHR12002:SF41 CLAUDIN CLAUDIN-6 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=18424|UniProtKB=Q9HCK5 Q9HCK5 AGO4 PTHR22891:SF26 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-4 translation initiation factor#PC00224 HUMAN|HGNC=21147|UniProtKB=Q9H9V4 Q9H9V4 RNF122 PTHR22763:SF14 RING ZINC FINGER PROTEIN RING FINGER PROTEIN 122 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=17152|UniProtKB=Q9Y305 Q9Y305 ACOT9 PTHR12655:SF0 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;cellular amide metabolic process#GO:0043603;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 esterase#PC00097 HUMAN|HGNC=775|UniProtKB=P01008 P01008 SERPINC1 PTHR11461:SF53 SERINE PROTEASE INHIBITOR, SERPIN ANTITHROMBIN-III serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>ATIII#P00440 HUMAN|HGNC=18359|UniProtKB=Q8IW75 Q8IW75 SERPINA12 PTHR11461:SF157 SERINE PROTEASE INHIBITOR, SERPIN SERPIN A12 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=16708|UniProtKB=Q8N5H3 Q8N5H3 FAM89B PTHR46949:SF2 LEUCINE REPEAT ADAPTER PROTEIN 25 LEUCINE REPEAT ADAPTER PROTEIN 25 scaffold/adaptor protein#PC00226 HUMAN|HGNC=7629|UniProtKB=E9PAV3 E9PAV3 NACA PTHR21713:SF3 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=16904|UniProtKB=P54108 P54108 CRISP3 PTHR10334:SF525 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN 3 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 PI3 kinase pathway#P00048>scl-1#G01545 HUMAN|HGNC=1685|UniProtKB=P06127 P06127 CD5 PTHR47309:SF1 T-CELL SURFACE GLYCOPROTEIN CD5 T-CELL SURFACE GLYCOPROTEIN CD5 lymphocyte activation#GO:0046649;regulation of cell-cell adhesion#GO:0022407;biological adhesion#GO:0022610;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;leukocyte cell-cell adhesion#GO:0007159;positive regulation of leukocyte activation#GO:0002696;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of cellular process#GO:0050794;regulation of leukocyte cell-cell adhesion#GO:1903037;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;positive regulation of T cell activation#GO:0050870;positive regulation of cell adhesion#GO:0045785;positive regulation of cell activation#GO:0050867;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;positive regulation of cell-cell adhesion#GO:0022409 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=12830|UniProtKB=O43542 O43542 XRCC3 PTHR46487:SF1 DNA REPAIR PROTEIN XRCC3 DNA REPAIR PROTEIN XRCC3 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;endodeoxyribonuclease activity#GO:0004520;four-way junction DNA binding#GO:0000400;deoxyribonuclease activity#GO:0004536 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;double-strand break repair#GO:0006302;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;biological regulation#GO:0065007;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;replication fork#GO:0005657 DNA metabolism protein#PC00009 HUMAN|HGNC=1505|UniProtKB=P49662 P49662 CASP4 PTHR10454:SF219 CASPASE CASPASE-4 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=16885|UniProtKB=Q9BRG2 Q9BRG2 SH2D3A PTHR14247:SF11 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 3A positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of protein modification process#GO:0031401;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=1099|UniProtKB=Q7Z569 Q7Z569 BRAP PTHR24007:SF7 BRCA1-ASSOCIATED PROTEIN BRCA1-ASSOCIATED PROTEIN HUMAN|HGNC=28458|UniProtKB=Q9BWN1 Q9BWN1 PRR14 PTHR14522:SF2 EMO2-RELATED PROLINE-RICH PROTEIN 14 HUMAN|HGNC=24474|UniProtKB=Q9H0N5 Q9H0N5 PCBD2 PTHR12599:SF0 PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE 2 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 dehydratase#PC00091 HUMAN|HGNC=21685|UniProtKB=Q6YHK3 Q6YHK3 CD109 PTHR11412:SF162 MACROGLOBULIN / COMPLEMENT CD109 ANTIGEN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=4324|UniProtKB=P43220 P43220 GLP1R PTHR45620:SF25 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON-LIKE PEPTIDE 1 RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=3590|UniProtKB=Q12884 Q12884 FAP PTHR11731:SF136 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED PROLYL ENDOPEPTIDASE FAP serine protease#PC00203 HUMAN|HGNC=7704|UniProtKB=Q9Y6M9 Q9Y6M9 NDUFB9 PTHR12868:SF1 NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=9405|UniProtKB=Q16512 Q16512 PKN1 PTHR24356:SF246 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE N1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 HUMAN|HGNC=5235|UniProtKB=P54652 P54652 HSPA2 PTHR19375:SF382 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK-RELATED 70 KDA PROTEIN 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524;ATPase activity#GO:0016887 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;chaperone-mediated protein folding#GO:0061077;cellular response to organic substance#GO:0071310;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;'de novo' protein folding#GO:0006458;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 HUMAN|HGNC=11390|UniProtKB=Q96GD4 Q96GD4 AURKB PTHR24350:SF4 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE B transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cell division#GO:0051301;mitotic spindle organization#GO:0007052;membrane fission#GO:0090148;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;regulation of cell division#GO:0051302;mitotic cell cycle process#GO:1903047;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;spindle organization#GO:0007051;cytokinesis#GO:0000910;regulation of cytokinesis#GO:0032465 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome#GO:0000794;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;centrosome#GO:0005813;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;spindle#GO:0005819;microtubule#GO:0005874;membrane-enclosed lumen#GO:0031974;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;organelle lumen#GO:0043233;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome, centromeric region#GO:0000780;supramolecular fiber#GO:0099512;centriole#GO:0005814;polymeric cytoskeletal fiber#GO:0099513;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=35475|UniProtKB=A8MYZ0 A8MYZ0 MINDY4B PTHR12473:SF12 UNCHARACTERIZED INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4B hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 HUMAN|HGNC=2236|UniProtKB=Q9Y678 Q9Y678 COPG1 PTHR10261:SF3 COATOMER SUBUNIT GAMMA COATOMER SUBUNIT GAMMA-1 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;organelle localization#GO:0051640;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of organelle localization#GO:0051656;secretion by cell#GO:0032940;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport along microtubule#GO:0010970;protein localization#GO:0008104;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;organelle transport along microtubule#GO:0072384;export from cell#GO:0140352 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;COPI vesicle coat#GO:0030126;intracellular#GO:0005622;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=20954|UniProtKB=Q9NP79 Q9NP79 VTA1 PTHR46009:SF1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;endosome transport via multivesicular body sorting pathway#GO:0032509;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;late endosome to vacuole transport#GO:0045324;intracellular transport#GO:0046907;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=26281|UniProtKB=Q6ZN84 Q6ZN84 CCDC81 PTHR14362:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 81 COILED-COIL DOMAIN-CONTAINING PROTEIN 81 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=21237|UniProtKB=Q9BRT2 Q9BRT2 UQCC2 PTHR34260:SF1 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 chaperone#PC00072 HUMAN|HGNC=1689|UniProtKB=P13987 P13987 CD59 PTHR10036:SF3 CD59 GLYCOPROTEIN CD59 GLYCOPROTEIN HUMAN|HGNC=23088|UniProtKB=Q0GE19 Q0GE19 SLC10A7 PTHR18640:SF5 SOLUTE CARRIER FAMILY 10 MEMBER 7 SODIUM/BILE ACID COTRANSPORTER 7 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=11809|UniProtKB=P35590 P35590 TIE1 PTHR24416:SF341 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TIE-1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=10809|UniProtKB=Q13326 Q13326 SGCG PTHR12939:SF4 SARCOGLYCAN GAMMA-SARCOGLYCAN blood circulation#GO:0008015;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;heart contraction#GO:0060047;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;system process#GO:0003008;developmental process#GO:0032502;circulatory system process#GO:0003013;tissue development#GO:0009888;muscle tissue development#GO:0060537;system development#GO:0048731;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;heart process#GO:0003015 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;sarcolemma#GO:0042383 cytoskeletal protein#PC00085 HUMAN|HGNC=29273|UniProtKB=Q9P2D3 Q9P2D3 HEATR5B PTHR21663:SF2 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5B endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 HUMAN|HGNC=13541|UniProtKB=O43861 O43861 ATP9B PTHR24092:SF50 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IIB-RELATED pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;vesicle budding from membrane#GO:0006900;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;vesicle organization#GO:0016050;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=26842|UniProtKB=Q494V2 Q494V2 CFAP100 PTHR21683:SF5 UNCHARACTERIZED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 100 HUMAN|HGNC=28401|UniProtKB=Q8TBY0 Q8TBY0 RBM46 PTHR21245:SF3 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 46-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=14681|UniProtKB=Q9UM82 Q9UM82 SPATA2 PTHR15326:SF8 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC SPERMATOGENESIS-ASSOCIATED PROTEIN 2 signal transduction#GO:0007165;response to cytokine#GO:0034097;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein K63-linked deubiquitination#GO:0070536;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;cell death#GO:0008219;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;protein modification by small protein conjugation or removal#GO:0070647;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;tumor necrosis factor-mediated signaling pathway#GO:0033209;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to tumor necrosis factor#GO:0034612;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular response to tumor necrosis factor#GO:0071356 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=14638|UniProtKB=Q86UQ4 Q86UQ4 ABCA13 PTHR19229:SF113 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 13 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=25595|UniProtKB=Q5T7N2 Q5T7N2 L1TD1 PTHR11505:SF203 L1 TRANSPOSABLE ELEMENT-RELATED LINE-1 TYPE TRANSPOSASE DOMAIN-CONTAINING PROTEIN 1 single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular process#GO:0009987;transposition#GO:0032196 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 HUMAN|HGNC=14559|UniProtKB=Q9UJZ1 Q9UJZ1 STOML2 PTHR43327:SF10 STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL transporter#PC00227 HUMAN|HGNC=28445|UniProtKB=Q8NB15 Q8NB15 ZNF511 PTHR21354:SF0 UNCHARACTERIZED ZINC FINGER PROTEIN 511 HUMAN|HGNC=11786|UniProtKB=P35442 P35442 THBS2 PTHR10199:SF10 THROMBOSPONDIN THROMBOSPONDIN-2 negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;system development#GO:0048731;negative regulation of multicellular organismal process#GO:0051241;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;regulation of developmental process#GO:0050793;tube morphogenesis#GO:0035239;regulation of vasculature development#GO:1901342;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;vasculature development#GO:0001944;multicellular organismal process#GO:0032501 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular region#GO:0005576 HUMAN|HGNC=6757|UniProtKB=Q13394 Q13394 MAB21L1 PTHR10656:SF38 CELL FATE DETERMINING PROTEIN MAB21-RELATED NUCLEOTIDYLTRANSFERASE MAB21L1-RELATED HUMAN|HGNC=18931|UniProtKB=Q3LI64 Q3LI64 KRTAP6-1 PTHR31678:SF2 KERATIN-ASSOCIATED PROTEIN 6-3 KERATIN-ASSOCIATED PROTEIN 6-1 HUMAN|HGNC=28961|UniProtKB=Q15004 Q15004 PCLAF PTHR15679:SF8 PCNA-ASSOCIATED FACTOR PCNA-ASSOCIATED FACTOR binding#GO:0005488;chromatin binding#GO:0003682 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|Ensembl=ENSG00000261667|UniProtKB=H3BQJ8 H3BQJ8 LY6L PTHR32217:SF2 LYMPHOCYTE ANTIGEN 6H LYMPHOCYTE ANTIGEN 6L HUMAN|HGNC=24515|UniProtKB=O95563 O95563 MPC2 PTHR14154:SF2 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 2 HUMAN|HGNC=32325|UniProtKB=Q5VTH2 Q5VTH2 CFAP126 PTHR34639:SF1 PROTEIN FLATTOP PROTEIN FLATTOP cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=19398|UniProtKB=Q96JS3 Q96JS3 PGBD1 PTHR23226:SF9 ZINC FINGER AND SCAN DOMAIN-CONTAINING PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25236|UniProtKB=Q9NUC0 Q9NUC0 SERTAD4 PTHR14272:SF4 SERTA DOMAIN-CONTAINING PROTEIN 4 SERTA DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=27717|UniProtKB=Q96FX2 Q96FX2 DPH3 PTHR21454:SF24 DPH3 HOMOLOG-RELATED DPH3 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;posttranscriptional regulation of gene expression#GO:0010608;tRNA metabolic process#GO:0006399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;translation#GO:0006412;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;tRNA wobble uridine modification#GO:0002098;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16396|UniProtKB=Q9BZF1 Q9BZF1 OSBPL8 PTHR10972:SF102 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 8 lipid binding#GO:0008289;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;lipid transporter activity#GO:0005319;steroid binding#GO:0005496;sterol binding#GO:0032934 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18341|UniProtKB=Q9Y2J8 Q9Y2J8 PADI2 PTHR10837:SF12 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE TYPE-2 HUMAN|HGNC=6141|UniProtKB=P08648 P08648 ITGA5 PTHR23220:SF3 INTEGRIN ALPHA INTEGRIN ALPHA-5 integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=26660|UniProtKB=A6NC78 A6NC78 GOLGA8IP PTHR10881:SF62 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8H-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=15483|UniProtKB=Q8IVW4 Q8IVW4 CDKL3 PTHR24056:SF177 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 3 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=1421|UniProtKB=O43772 O43772 SLC25A20 PTHR45624:SF4 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL CARNITINE/ACYLCARNITINE CARRIER PROTEIN transporter#PC00227 HUMAN|HGNC=2505|UniProtKB=P16410 P16410 CTLA4 PTHR11494:SF8 CYTOTOXIC T-LYMPHOCYTE PROTEIN CYTOTOXIC T-LYMPHOCYTE PROTEIN 4 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;regulation of cell-cell adhesion#GO:0022407;B cell receptor signaling pathway#GO:0050853;regulation of T cell activation#GO:0050863;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;immune response-activating signal transduction#GO:0002757;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;regulation of multicellular organismal process#GO:0051239;negative regulation of T cell activation#GO:0050868;immune system development#GO:0002520;regulation of immune response#GO:0050776;cell communication#GO:0007154;cell adhesion#GO:0007155;T cell differentiation#GO:0030217;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of cell-cell adhesion#GO:0022408;animal organ development#GO:0048513;biological adhesion#GO:0022610;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;leukocyte cell-cell adhesion#GO:0007159;positive regulation of response to stimulus#GO:0048584;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;system development#GO:0048731;regulation of hemopoiesis#GO:1903706;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;multicellular organism development#GO:0007275;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;lymphocyte differentiation#GO:0030098;T cell activation#GO:0042110;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=3521|UniProtKB=Q99504 Q99504 EYA3 PTHR10190:SF5 EYES ABSENT EYES ABSENT HOMOLOG 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of apoptotic signaling pathway#GO:2001233;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;negative regulation of apoptotic signaling pathway#GO:2001234;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;protein dephosphorylation#GO:0006470;histone modification#GO:0016570;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;response to stress#GO:0006950;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;chromatin organization#GO:0006325;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of DNA repair#GO:0045739;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;protein modification process#GO:0036211;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of DNA repair#GO:0006282;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;negative regulation of programmed cell death#GO:0043069;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cell death#GO:0008219;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of cell death#GO:0010941;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=7572|UniProtKB=Q9UKX2 Q9UKX2 MYH2 PTHR45615:SF39 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-2 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=6764|UniProtKB=Q9UI95 Q9UI95 MAD2L2 PTHR11842:SF10 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B DNA polymerase complex#GO:0042575;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 HUMAN|HGNC=25002|UniProtKB=Q9H0I3 Q9H0I3 CCDC113 PTHR15654:SF2 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 113 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=31926|UniProtKB=P0C7V9 P0C7V9 METTL15P1 PTHR11265:SF1 S-ADENOSYL-METHYLTRANSFERASE MRAW 12S RRNA N4-METHYLCYTIDINE (M4C) METHYLTRANSFERASE-RELATED catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 methyltransferase#PC00155 HUMAN|HGNC=25984|UniProtKB=Q8NE00 Q8NE00 TMEM104 PTHR16189:SF0 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 104 HUMAN|HGNC=15586|UniProtKB=Q9HBW1 Q9HBW1 LRRC4 PTHR24369:SF9 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4 HUMAN|HGNC=20064|UniProtKB=Q9H0E7 Q9H0E7 USP44 PTHR21646:SF15 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 44 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=30308|UniProtKB=Q96B86 Q96B86 RGMA PTHR31428:SF4 RGM DOMAIN FAMILY MEMBER DRAG-1 REPULSIVE GUIDANCE MOLECULE A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=2959|UniProtKB=Q13609 Q13609 DNASE1L3 PTHR11371:SF32 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE GAMMA hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;endodeoxyribonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;deoxyribonuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;DNA catabolic process, endonucleolytic#GO:0000737;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=9238|UniProtKB=Q06203 Q06203 PPAT PTHR11907:SF20 AMIDOPHOSPHORIBOSYLTRANSFERASE AMIDOPHOSPHORIBOSYLTRANSFERASE transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 transferase#PC00220 De novo purine biosynthesis#P02738>Amidophosphoribosyl transferase#P02905 HUMAN|HGNC=26346|UniProtKB=Q96LL3 Q96LL3 C16orf92 PTHR38648:SF1 RIKEN CDNA 4930451I11 GENE RIKEN CDNA 4930451I11 GENE HUMAN|HGNC=29199|UniProtKB=Q9ULS5 Q9ULS5 TMCC3 PTHR17613:SF8 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN PROTEIN 3 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=16262|UniProtKB=P46937 P46937 YAP1 PTHR17616:SF9 YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER TRANSCRIPTIONAL COACTIVATOR YAP1 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;hippo signaling#GO:0035329;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 HUMAN|HGNC=12188|UniProtKB=A0A0A6YYD4 A0A0A6YYD4 TRBV13 PTHR23268:SF75 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 13 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=9678|UniProtKB=Q16827 Q16827 PTPRO PTHR47028:SF1 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE O RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE O phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine phosphatase activity#GO:0004725;Wnt-protein binding#GO:0017147;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;nervous system development#GO:0007399;regulation of biological process#GO:0050789;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;regulation of multicellular organismal process#GO:0051239;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cell-cell signaling by wnt#GO:0198738;circulatory system process#GO:0003013;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;taxis#GO:0042330;signal transduction#GO:0007165;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of system process#GO:0044057;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;neuron differentiation#GO:0030182;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;chemotaxis#GO:0006935;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cell morphogenesis involved in differentiation#GO:0000904;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092;neuron projection guidance#GO:0097485;regulation of protein modification process#GO:0031399;negative regulation of kinase activity#GO:0033673;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;system process#GO:0003008;kidney development#GO:0001822;plasma membrane bounded cell projection organization#GO:0120036;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;axonogenesis#GO:0007409;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;regulation of body fluid levels#GO:0050878;negative regulation of protein metabolic process#GO:0051248;regulation of response to stimulus#GO:0048583;neuron projection development#GO:0031175;axon development#GO:0061564;movement of cell or subcellular component#GO:0006928;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;negative regulation of Wnt signaling pathway#GO:0030178;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;blood circulation#GO:0008015;negative regulation of cellular metabolic process#GO:0031324;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;urogenital system development#GO:0001655;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;negative regulation of transferase activity#GO:0051348;metabolic process#GO:0008152;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;multicellular organism development#GO:0007275;regulation of systemic arterial blood pressure#GO:0003073;epithelial cell differentiation#GO:0030855;regulation of canonical Wnt signaling pathway#GO:0060828;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of blood pressure#GO:0008217;negative regulation of phosphorylation#GO:0042326;regulation of Wnt signaling pathway#GO:0030111;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=24003|UniProtKB=Q8WXA8 Q8WXA8 HTR3C PTHR18945:SF764 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3C signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422 HUMAN|HGNC=29360|UniProtKB=Q7L8J4 Q7L8J4 SH3BP5L PTHR19423:SF8 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5-LIKE protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;phosphorylation#GO:0016310;negative regulation of transferase activity#GO:0051348;protein metabolic process#GO:0019538;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=19374|UniProtKB=O15226 O15226 NKRF PTHR16148:SF15 NF-KAPPA-B-REPRESSING FACTOR-RELATED NF-KAPPA-B-REPRESSING FACTOR membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=20748|UniProtKB=Q9NW38 Q9NW38 FANCL PTHR13206:SF0 UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN E3 UBIQUITIN-PROTEIN LIGASE FANCL ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=8324|UniProtKB=Q8NH48 Q8NH48 OR5B3 PTHR48018:SF102 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5B3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=2356|UniProtKB=P24387 P24387 CRHBP PTHR10278:SF0 CORTICOTROPIN-RELEASING FACTOR-BINDING PROTEIN CORTICOTROPIN-RELEASING FACTOR-BINDING PROTEIN peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;system process#GO:0003008;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of system process#GO:0044057;peptide secretion#GO:0002790;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;negative regulation of multicellular organismal process#GO:0051241;regulation of peptide secretion#GO:0002791;hormone secretion#GO:0046879;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;cellular response to hormone stimulus#GO:0032870;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;secretion#GO:0046903;regulation of secretion#GO:0051046;regulation of signal transduction#GO:0009966;peptide hormone secretion#GO:0030072;regulation of hormone secretion#GO:0046883;signal release#GO:0023061;hormone transport#GO:0009914;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;regulation of peptide hormone secretion#GO:0090276;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;negative regulation of transport#GO:0051051;cellular process#GO:0009987;peptide transport#GO:0015833;regulation of hormone levels#GO:0010817;localization#GO:0051179;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;export from cell#GO:0140352;regulation of peptide transport#GO:0090087;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=16636|UniProtKB=O60333 O60333 KIF1B PTHR24115:SF328 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;ATP-dependent microtubule motor activity, plus-end-directed#GO:0008574;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 supramolecular complex#GO:0099080;somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;dendrite#GO:0030425;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;neuron projection#GO:0043005;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 HUMAN|HGNC=20525|UniProtKB=P60410 P60410 KRTAP10-8 PTHR23262:SF149 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-8 HUMAN|HGNC=26388|UniProtKB=Q6ZRI8 Q6ZRI8 ARHGAP36 PTHR12635:SF8 RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER RHO GTPASE-ACTIVATING PROTEIN 36 GTPase-activating protein#PC00257 HUMAN|HGNC=1490|UniProtKB=P47755 P47755 CAPZA2 PTHR10653:SF2 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cortical actin cytoskeleton#GO:0030864;actin cortical patch#GO:0030479;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=25920|UniProtKB=Q8NCJ5 Q8NCJ5 SPRYD3 PTHR12864:SF54 RAN BINDING PROTEIN 9-RELATED SPRY DOMAIN-CONTAINING PROTEIN 3 scaffold/adaptor protein#PC00226 HUMAN|HGNC=34427|UniProtKB=Q68DQ2 Q68DQ2 CRYBG3 PTHR11818:SF38 BETA/GAMMA CRYSTALLIN VERY LARGE A-KINASE ANCHOR PROTEIN structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=20097|UniProtKB=Q96LQ0 Q96LQ0 PPP1R36 PTHR21055:SF3 UNCHARACTERIZED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 36 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;negative regulation of phosphatase activity#GO:0010923;negative regulation of phosphorus metabolic process#GO:0010563;regulation of phosphatase activity#GO:0010921;regulation of dephosphorylation#GO:0035303;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of catalytic activity#GO:0050790;negative regulation of dephosphorylation#GO:0035305;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of hydrolase activity#GO:0051336;negative regulation of catalytic activity#GO:0043086;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 HUMAN|HGNC=27321|UniProtKB=Q96QK8 Q96QK8 SMIM14 PTHR31019:SF1 UNCHARACTERIZED SMALL INTEGRAL MEMBRANE PROTEIN 14 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=16718|UniProtKB=Q9H6R0 Q9H6R0 DHX33 PTHR18934:SF118 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX33 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;transcription by RNA polymerase I#GO:0006360;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA helicase#PC00032 HUMAN|HGNC=20082|UniProtKB=Q8N8A6 Q8N8A6 DDX51 PTHR24031:SF68 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX51 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=15981|UniProtKB=Q8WUU4 Q8WUU4 ZNF296 PTHR45993:SF2 B-CELL LYMPHOMA/LEUKEMIA 11 ZINC FINGER PROTEIN 296 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;dendrite development#GO:0016358;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;negative regulation of cellular component organization#GO:0051129;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;primary metabolic process#GO:0044238;regulation of neuron projection development#GO:0010975;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;aromatic compound biosynthetic process#GO:0019438;neuron development#GO:0048666;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28426|UniProtKB=Q96B36 Q96B36 AKT1S1 PTHR21844:SF2 AKT1 SUBSTRATE 1 PROTEIN PROLINE-RICH AKT1 SUBSTRATE 1 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 CCKR signaling map#P06959>PRAS40#P07076 HUMAN|HGNC=32221|UniProtKB=Q96G04 Q96G04 EEF2KMT PTHR14614:SF117 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT-RELATED N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;nitrogen compound metabolic process#GO:0006807;peptidyl-lysine trimethylation#GO:0018023;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=16613|UniProtKB=Q5TA78 Q5TA78 LCE4A PTHR23263:SF139 SMALL PROLINE-RICH PROTEIN LATE CORNIFIED ENVELOPE PROTEIN 4A HUMAN|HGNC=30057|UniProtKB=O14626 O14626 GPR171 PTHR24233:SF4 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 171-RELATED nucleotide binding#GO:0000166;signaling receptor activity#GO:0038023;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=23215|UniProtKB=Q8TEQ8 Q8TEQ8 PIGO PTHR23071:SF1 PHOSPHATIDYLINOSITOL GLYCAN GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=14976|UniProtKB=Q9UMY4 Q9UMY4 SNX12 PTHR45963:SF3 RE52028P SORTING NEXIN-12 phosphatidylinositol-3-phosphate binding#GO:0032266;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;establishment of protein localization#GO:0045184;amide transport#GO:0042886;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;endocytic recycling#GO:0032456;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of protein transport#GO:0051223;regulation of protein localization#GO:0032880;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;cytosolic transport#GO:0016482;protein localization#GO:0008104;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=1497|UniProtKB=O14936 O14936 CASK PTHR23122:SF40 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PERIPHERAL PLASMA MEMBRANE PROTEIN CASK scaffold/adaptor protein#PC00226 Parkinson disease#P00049>CASK#P01232;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847 HUMAN|HGNC=6642|UniProtKB=P25791 P25791 LMO2 PTHR45787:SF3 LD11652P RHOMBOTIN-2 HUMAN|HGNC=582|UniProtKB=Q92870 Q92870 APBB2 PTHR14058:SF11 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 2 amyloid-beta binding#GO:0001540;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126 HUMAN|HGNC=6373|UniProtKB=Q12918 Q12918 KLRB1 PTHR46784:SF1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY B MEMBER 1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY B MEMBER 1 transmembrane signal receptor#PC00197 HUMAN|HGNC=2092|UniProtKB=Q00610 Q00610 CLTC PTHR10292:SF7 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN 1 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;membrane organization#GO:0061024;nuclear division#GO:0000280;transport#GO:0006810;endocytosis#GO:0006897;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;protein-containing complex subunit organization#GO:0043933 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;endocytic vesicle#GO:0030139;cytoskeleton#GO:0005856;spindle#GO:0005819 vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 HUMAN|HGNC=32545|UniProtKB=P0C7T8 P0C7T8 TMEM253 PTHR37359:SF1 TRANSMEMBRANE PROTEIN 253 TRANSMEMBRANE PROTEIN 253 HUMAN|HGNC=17693|UniProtKB=O75911 O75911 DHRS3 PTHR24322:SF483 PKSB SHORT-CHAIN DEHYDROGENASE/REDUCTASE 3 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=11305|UniProtKB=Q96SB4 Q96SB4 SRPK1 PTHR24055:SF0 MITOGEN-ACTIVATED PROTEIN KINASE SRSF PROTEIN KINASE 1 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;regulation of mRNA processing#GO:0050684;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;signaling#GO:0023052;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=23484|UniProtKB=Q5VWN6 Q5VWN6 TASOR2 PTHR16207:SF10 UNCHARACTERIZED PROTEIN TASOR 2 HUMAN|HGNC=2230|UniProtKB=P53621 P53621 COPA PTHR19876:SF1 COATOMER COATOMER SUBUNIT ALPHA endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;COPI vesicle coat#GO:0030126;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=29136|UniProtKB=O94953 O94953 KDM4B PTHR10694:SF30 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4B 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|Ensembl=ENSG00000232113|UniProtKB=A0A1B0GTY4 A0A1B0GTY4 TEX50 PTHR39232:SF1 TESTIS-EXPRESSED PROTEIN 50 TESTIS-EXPRESSED PROTEIN 50 HUMAN|HGNC=11545|UniProtKB=Q16514 Q16514 TAF12 PTHR12264:SF21 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;TBP-class protein binding#GO:0017025;DNA binding#GO:0003677;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;transcription factor binding#GO:0008134 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=30922|UniProtKB=Q8NG48 Q8NG48 LINS1 PTHR16057:SF1 WINS1, 2 PROTEIN PROTEIN LINES HOMOLOG 1 HUMAN|HGNC=24589|UniProtKB=Q4L180 Q4L180 FILIP1L PTHR23166:SF4 FILAMIN/GPBP-INTERACTING PROTEIN FILAMIN A-INTERACTING PROTEIN 1-LIKE HUMAN|HGNC=643|UniProtKB=O43315 O43315 AQP9 PTHR43829:SF6 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-9 amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 HUMAN|HGNC=32376|UniProtKB=Q0D2H9 Q0D2H9 GOLGA8DP PTHR10881:SF7 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8C-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=19140|UniProtKB=Q5TCY1 Q5TCY1 TTBK1 PTHR11909:SF297 CASEIN KINASE-RELATED TAU-TUBULIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-tyrosine modification#GO:0018212;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=34354|UniProtKB=A6NJJ6 A6NJJ6 C19orf67 PTHR36292:SF1 UPF0575 PROTEIN C19ORF67 UPF0575 PROTEIN C19ORF67 HUMAN|HGNC=29829|UniProtKB=Q6DT37 Q6DT37 CDC42BPG PTHR22988:SF22 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE/THREONINE-PROTEIN KINASE MRCK GAMMA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;actomyosin structure organization#GO:0031032;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;actin cytoskeleton organization#GO:0030036;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=15621|UniProtKB=Q5M8T2 Q5M8T2 SLC35D3 PTHR11132:SF282 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER D3 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide-sugar transmembrane transporter activity#GO:0005338;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=19839|UniProtKB=Q96NE9 Q96NE9 FRMD6 PTHR23280:SF9 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN 6 HUMAN|HGNC=9750|UniProtKB=P20742 P20742 PZP PTHR11412:SF92 MACROGLOBULIN / COMPLEMENT PREGNANCY ZONE PROTEIN peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase inhibitor activity#GO:0004866;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=27158|UniProtKB=A8MPS7 A8MPS7 YDJC PTHR31609:SF1 YDJC DEACETYLASE FAMILY MEMBER CARBOHYDRATE DEACETYLASE HUMAN|HGNC=24660|UniProtKB=Q8IX06 Q8IX06 REXO1L1P PTHR12801:SF22 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED EXONUCLEASE GOR-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 exoribonuclease#PC00099 HUMAN|HGNC=37233|UniProtKB=A8MRT5 A8MRT5 NPIPB5 PTHR15438:SF5 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER B11-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=24204|UniProtKB=Q5THR3 Q5THR3 EFCAB6 PTHR20875:SF2 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 calmodulin-related#PC00061 HUMAN|HGNC=19104|UniProtKB=O75161 O75161 NPHP4 PTHR31043:SF3 NEPHROCYSTIN-4 NEPHROCYSTIN-4 HUMAN|HGNC=15605|UniProtKB=Q86WV1 Q86WV1 SKAP1 PTHR15129:SF1 SRC-ASSOCIATED ADAPTOR PROTEIN SRC KINASE-ASSOCIATED PHOSPHOPROTEIN 1 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|Ensembl=ENSG00000276565|UniProtKB=Q6YL49 Q6YL49 ENSG00000276565 PTHR35846:SF1 PROTEIN CBG05131 PRESAN DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=3373|UniProtKB=Q09472 Q09472 EP300 PTHR13808:SF29 CBP/P300-RELATED HISTONE ACETYLTRANSFERASE P300 transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;nucleic acid binding#GO:0003676;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;transcription factor binding#GO:0008134;N-acyltransferase activity#GO:0016410;transcription coregulator activity#GO:0003712;histone acetyltransferase activity#GO:0004402;transcription regulator activity#GO:0140110;chromatin DNA binding#GO:0031490;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;peptide-lysine-N-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II transcription factor binding#GO:0001085;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone acetyltransferase complex#GO:0000123;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;p53 pathway#P00059>CBP#P04623;Wnt signaling pathway#P00057>CBP#P01448;Gonadotropin-releasing hormone receptor pathway#P06664>p300#P06737;Transcription regulation by bZIP transcription factor#P00055>CBP/P300#P01387;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Huntington disease#P00029>CBP#P00777;p53 pathway#P00059>P300#P04611 HUMAN|HGNC=9758|UniProtKB=P62820 P62820 RAB1A PTHR24073:SF963 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1A GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;vacuole organization#GO:0007033;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;autophagosome assembly#GO:0000045;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;autophagosome organization#GO:1905037;intracellular transport#GO:0046907;autophagy#GO:0006914 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=4876|UniProtKB=Q15034 Q15034 HERC3 PTHR45622:SF18 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC3-RELATED ubiquitin-protein ligase#PC00234 HUMAN|HGNC=31046|UniProtKB=Q96GZ6 Q96GZ6 SLC41A3 PTHR16228:SF22 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=15736|UniProtKB=Q8IV36 Q8IV36 HID1 PTHR21575:SF12 PROTEIN HID1 PROTEIN HID1 Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=1725|UniProtKB=P30304 P30304 CDC25A PTHR10828:SF46 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 M-PHASE INDUCER PHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cell cycle process#GO:0022402;positive regulation of cell cycle#GO:0045787;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;meiotic cell cycle process#GO:1903046;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;positive regulation of biological process#GO:0048518;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle phase transition#GO:1901990;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;reproduction#GO:0000003;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 p53 pathway#P00059>Cdc25C#P04624 HUMAN|HGNC=28352|UniProtKB=Q9H467 Q9H467 CUEDC2 PTHR12493:SF0 CUE DOMAIN CONTAINING 2 CUE DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=8494|UniProtKB=Q9Y226 Q9Y226 SLC22A13 PTHR24064:SF198 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 13 secondary carrier transporter#PC00258 HUMAN|HGNC=10610|UniProtKB=P51671 P51671 CCL11 PTHR12015:SF146 SMALL INDUCIBLE CYTOKINE A EOTAXIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=15488|UniProtKB=Q9NPF7 Q9NPF7 IL23A PTHR15947:SF0 SGRF INTERLEUKIN-23 SUBUNIT ALPHA regulation of protein metabolic process#GO:0051246;positive regulation of signal transduction#GO:0009967;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;positive regulation of lymphocyte activation#GO:0051251;regulation of biological process#GO:0050789;peptidyl-tyrosine phosphorylation#GO:0018108;positive regulation of receptor signaling pathway via STAT#GO:1904894;regulation of adaptive immune response#GO:0002819;cellular protein metabolic process#GO:0044267;leukocyte activation#GO:0045321;lymphocyte activation involved in immune response#GO:0002285;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cell adhesion#GO:0007155;cell fate commitment#GO:0045165;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell activation#GO:0001775;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;signal transduction#GO:0007165;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;biological adhesion#GO:0022610;hematopoietic or lymphoid organ development#GO:0048534;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;positive regulation of T cell proliferation#GO:0042102;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;positive regulation of adaptive immune response#GO:0002821;leukocyte cell-cell adhesion#GO:0007159;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;T cell proliferation#GO:0042098;positive regulation of transferase activity#GO:0051347;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;immune effector process#GO:0002252;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;immune response#GO:0006955;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of T cell proliferation#GO:0042129;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;receptor signaling pathway via STAT#GO:0097696;regulation of mononuclear cell proliferation#GO:0032944;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;regulation of lymphocyte proliferation#GO:0050670;positive regulation of kinase activity#GO:0033674;positive regulation of T cell activation#GO:0050870;positive regulation of cell adhesion#GO:0045785;regulation of protein modification process#GO:0031399;regulation of cell-cell adhesion#GO:0022407;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;positive regulation of leukocyte activation#GO:0002696;regulation of phosphorus metabolic process#GO:0051174;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of molecular function#GO:0065009;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of signal transduction#GO:0009966;positive regulation of immune effector process#GO:0002699;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;regulation of kinase activity#GO:0043549;alpha-beta T cell differentiation#GO:0046632;cellular developmental process#GO:0048869;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of T cell differentiation#GO:0045582;T cell differentiation#GO:0030217;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;positive regulation of cell activation#GO:0050867;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;animal organ development#GO:0048513;developmental process#GO:0032502;peptidyl-amino acid modification#GO:0018193;regulation of cell differentiation#GO:0045595;regulation of receptor signaling pathway via STAT#GO:1904892;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;regulation of hemopoiesis#GO:1903706;positive regulation of metabolic process#GO:0009893;positive regulation of leukocyte cell-cell adhesion#GO:1903039;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;receptor signaling pathway via JAK-STAT#GO:0007259;metabolic process#GO:0008152;lymphocyte activation#GO:0046649;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of developmental process#GO:0051094;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;positive regulation of protein kinase activity#GO:0045860;T cell activation#GO:0042110;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of leukocyte proliferation#GO:0070663;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell-cell adhesion#GO:0022409;regulation of transferase activity#GO:0051338 extracellular space#GO:0005615;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=19893|UniProtKB=Q6QNK2 Q6QNK2 ADGRD1 PTHR12011:SF216 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR D1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=27424|UniProtKB=Q5T481 Q5T481 RBM20 PTHR15592:SF11 MATRIN 3/NUCLEAR PROTEIN 220-RELATED RNA-BINDING PROTEIN 20 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;RNA processing#GO:0006396;biosynthetic process#GO:0009058;translation#GO:0006412;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10362|UniProtKB=Q02878 Q02878 RPL6 PTHR10715:SF7 60S RIBOSOMAL PROTEIN L6 60S RIBOSOMAL PROTEIN L6 structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=2665|UniProtKB=P08174 P08174 CD55 PTHR19325:SF317 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT DECAY-ACCELERATING FACTOR HUMAN|HGNC=21015|UniProtKB=Q7Z7B0 Q7Z7B0 FILIP1 PTHR23166:SF3 FILAMIN/GPBP-INTERACTING PROTEIN FILAMIN-A-INTERACTING PROTEIN 1 HUMAN|HGNC=6366|UniProtKB=Q9Y337 Q9Y337 KLK5 PTHR24271:SF59 KALLIKREIN-RELATED KALLIKREIN-5 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=403|UniProtKB=P51648 P51648 ALDH3A2 PTHR43570:SF9 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER A2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=21485|UniProtKB=Q96NH3 Q96NH3 TBC1D32 PTHR13465:SF3 UPF0183 PROTEIN PROTEIN BROAD-MINDED vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 HUMAN|HGNC=17123|UniProtKB=Q96T83 Q96T83 SLC9A7 PTHR10110:SF62 SODIUM/HYDROGEN EXCHANGER SODIUM/HYDROGEN EXCHANGER 7 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=17038|UniProtKB=Q99685 Q99685 MGLL PTHR11614:SF179 PHOSPHOLIPASE-RELATED MONOGLYCERIDE LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phospholipase#PC00186 HUMAN|HGNC=30761|UniProtKB=Q8NDW8 Q8NDW8 TTC21A PTHR14699:SF2 STI2 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 21A microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;intraciliary retrograde transport#GO:0035721;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;intraciliary transport particle#GO:0030990 HUMAN|HGNC=29595|UniProtKB=Q6UW15 Q6UW15 REG3G PTHR22803:SF111 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED REGENERATING ISLET-DERIVED PROTEIN 3-GAMMA carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 response to organic substance#GO:0010033;response to external biotic stimulus#GO:0043207;response to oxygen-containing compound#GO:1901700;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;response to peptide hormone#GO:0043434;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;positive regulation of cell population proliferation#GO:0008284;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to organonitrogen compound#GO:0010243;cell population proliferation#GO:0008283;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607;response to chemical#GO:0042221;response to peptide#GO:1901652;antimicrobial humoral response#GO:0019730;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=820|UniProtKB=P51164 P51164 ATP4B PTHR11523:SF11 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;enzyme activator activity#GO:0008047;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;ATPase activator activity#GO:0001671;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;potassium ion transport#GO:0006813;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;metal ion transport#GO:0030001;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725;export from cell#GO:0140352 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=1349|UniProtKB=Q8IVG5 Q8IVG5 SAMD9L PTHR16155:SF18 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=31407|UniProtKB=A6NEK1 A6NEK1 ARRDC5 PTHR11188:SF17 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 5 amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;protein transport#GO:0015031;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=28474|UniProtKB=Q9BWS9 Q9BWS9 CHID1 PTHR46066:SF2 CHITINASE DOMAIN-CONTAINING PROTEIN 1 FAMILY MEMBER CHITINASE DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=27884|UniProtKB=Q4V9L6 Q4V9L6 TMEM119 PTHR28645:SF1 TRANSMEMBRANE PROTEIN 119 TRANSMEMBRANE PROTEIN 119 biomineralization#GO:0110148;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;regulation of cell population proliferation#GO:0042127;ossification#GO:0001503;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;positive regulation of cell population proliferation#GO:0008284;regulation of multicellular organismal development#GO:2000026;cell population proliferation#GO:0008283;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;bone mineralization#GO:0030282;tissue development#GO:0009888;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;system development#GO:0048731;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;biomineral tissue development#GO:0031214;positive regulation of biological process#GO:0048518;regulation of ossification#GO:0030278;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=14246|UniProtKB=Q9NPA2 Q9NPA2 MMP25 PTHR10201:SF142 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-25 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=6485|UniProtKB=O15230 O15230 LAMA5 PTHR10574:SF261 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-5 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=18809|UniProtKB=P68363 P68363 TUBA1B PTHR11588:SF251 TUBULIN TUBULIN ALPHA-1B CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Gonadotropin-releasing hormone receptor pathway#P06664>Tubulin#P06772 HUMAN|HGNC=1677|UniProtKB=P20963 P20963 CD247 PTHR10035:SF2 T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>TCR zeta#P01296 HUMAN|HGNC=25425|UniProtKB=Q5VVW2 Q5VVW2 GARNL3 PTHR15711:SF62 RAP GTPASE-ACTIVATING PROTEIN GTPASE-ACTIVATING RAP/RAN-GAP DOMAIN-LIKE PROTEIN 3 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1GAP#P00737 HUMAN|HGNC=27362|UniProtKB=P0C881 P0C881 RSPH10B PTHR46613:SF1 RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED HUMAN|HGNC=29062|UniProtKB=Q86YS7 Q86YS7 C2CD5 PTHR37412:SF2 C2 DOMAIN-CONTAINING PROTEIN 5 C2 DOMAIN-CONTAINING PROTEIN 5 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543 vesicle fusion#GO:0006906;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;positive regulation of organelle organization#GO:0010638;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;carbohydrate transport#GO:0008643;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;regulation of transport#GO:0051049;establishment of localization#GO:0051234;positive regulation of transmembrane transport#GO:0034764;vesicle organization#GO:0016050;regulation of protein transport#GO:0051223;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;organelle fusion#GO:0048284;protein localization to plasma membrane#GO:0072659;regulation of transmembrane transport#GO:0034762;transmembrane transport#GO:0055085;protein localization to membrane#GO:0072657;regulation of organelle organization#GO:0033043;regulation of protein localization to membrane#GO:1905475;protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;peptide transport#GO:0015833;carbohydrate transmembrane transport#GO:0034219;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=11935|UniProtKB=P29965 P29965 CD40LG PTHR11471:SF5 TUMOR NECROSIS FACTOR FAMILY MEMBER CD40 LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 HUMAN|HGNC=28273|UniProtKB=Q96A09 Q96A09 TENT5B PTHR12974:SF46 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5B adenylyltransferase activity#GO:0070566;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;negative regulation of cellular catabolic process#GO:0031330;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265 HUMAN|HGNC=2754|UniProtKB=Q9NUI1 Q9NUI1 DECR2 PTHR43296:SF2 PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE reductase#PC00198 HUMAN|HGNC=25501|UniProtKB=Q9NW68 Q9NW68 BSDC1 PTHR16019:SF5 SYNAPSE-ASSOCIATED PROTEIN BSD DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=2726|UniProtKB=P35638 P35638 DDIT3 PTHR16833:SF0 DNA DAMAGE-INDUCIBLE TRANSCRIPT 3 DDIT3 DNA DAMAGE-INDUCIBLE TRANSCRIPT 3 PROTEIN DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;cellular response to biotic stimulus#GO:0071216;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of transcription from RNA polymerase II promoter in response to stress#GO:0043618;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of response to stimulus#GO:0048584;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;positive regulation of programmed cell death#GO:0043068;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;cell death#GO:0008219;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;regulation of DNA-binding transcription factor activity#GO:0051090;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of cell death#GO:0010942;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of molecular function#GO:0044092;negative regulation of DNA-binding transcription factor activity#GO:0043433 cytoplasm#GO:0005737;RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;transcription regulator complex#GO:0005667;intracellular#GO:0005622 Oxidative stress response#P00046>CHOP#P01130 HUMAN|HGNC=6898|UniProtKB=P56192 P56192 MARS1 PTHR45765:SF1 METHIONINE--TRNA LIGASE METHIONINE--TRNA LIGASE, CYTOPLASMIC cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=26677|UniProtKB=Q8NA19 Q8NA19 L3MBTL4 PTHR12247:SF78 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 4 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=28656|UniProtKB=Q8IWF7 Q8IWF7 UBE2DNL PTHR24068:SF330 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D2-RELATED ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=8277|UniProtKB=O43869 O43869 OR2T1 PTHR26453:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T1 transmembrane signal receptor#PC00197 HUMAN|HGNC=18084|UniProtKB=Q8NET8 Q8NET8 TRPV3 PTHR10582:SF6 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 3 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;divalent metal ion transport#GO:0070838;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=32427|UniProtKB=O60309 O60309 LRRC37A3 PTHR23045:SF19 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A3 transmembrane signal receptor#PC00197 HUMAN|HGNC=895|UniProtKB=P37288 P37288 AVPR1A PTHR24241:SF17 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V1A RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;system process#GO:0003008;regulation of blood vessel diameter#GO:0097746;regulation of system process#GO:0044057;regulation of systemic arterial blood pressure#GO:0003073;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of multicellular organismal process#GO:0051240 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=19705|UniProtKB=Q86XS5 Q86XS5 ANGPTL5 PTHR19143:SF185 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 5 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=3344|UniProtKB=Q9NRM1 Q9NRM1 ENAM PTHR16784:SF2 ENAMELIN ENAMELIN structural protein#PC00211 HUMAN|HGNC=19920|UniProtKB=Q8IW50 Q8IW50 FAM219A PTHR31281:SF0 FAMILY NOT NAMED PROTEIN FAM219A HUMAN|HGNC=8550|UniProtKB=Q9UQ80 Q9UQ80 PA2G4 PTHR10804:SF130 PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P PROLIFERATION-ASSOCIATED PROTEIN 2G4 protease#PC00190 HUMAN|HGNC=14185|UniProtKB=Q5T6F2 Q5T6F2 UBAP2 PTHR16308:SF19 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER UBIQUITIN-ASSOCIATED PROTEIN 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9954|UniProtKB=Q04864 Q04864 REL PTHR24169:SF4 NUCLEAR FACTOR NF-KAPPA-B PROTEIN PROTO-ONCOGENE C-REL cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to external biotic stimulus#GO:0043207;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;innate immune response#GO:0045087;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;inflammatory response#GO:0006954;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;NIK/NF-kappaB signaling#GO:0038061;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Toll receptor signaling pathway#P00054>NFkappaB#P01354;Apoptosis signaling pathway#P00006>NFkappaB#P00297 HUMAN|HGNC=24835|UniProtKB=Q7Z2K8 Q7Z2K8 GPRIN1 PTHR15718:SF7 UNCHARACTERIZED G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 1 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=29209|UniProtKB=Q96A73 Q96A73 KIAA1191 PTHR28342:SF1 MONOOXYGENASE P33MONOX-RELATED MONOOXYGENASE P33MONOX-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxygenase#PC00177 HUMAN|HGNC=29583|UniProtKB=Q5JQS6 Q5JQS6 GCSAML PTHR35351:SF1 GERMINAL CENTER-ASSOCIATED SIGNALING AND MOTILITY-LIKE PROTEIN GERMINAL CENTER-ASSOCIATED SIGNALING AND MOTILITY-LIKE PROTEIN HUMAN|HGNC=27030|UniProtKB=Q5F1R6 Q5F1R6 DNAJC21 PTHR44029:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 chaperone#PC00072 HUMAN|HGNC=7602|UniProtKB=Q9Y4I1 Q9Y4I1 MYO5A PTHR13140:SF273 MYOSIN UNCONVENTIONAL MYOSIN-VA pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=11502|UniProtKB=O95473 O95473 SYNGR4 PTHR10838:SF22 SYNAPTOGYRIN SYNAPTOGYRIN-4 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=24338|UniProtKB=Q96EU7 Q96EU7 C1GALT1C1 PTHR23033:SF2 BETA1,3-GALACTOSYLTRANSFERASE C1GALT1-SPECIFIC CHAPERONE 1 transferase activity, transferring hexosyl groups#GO:0016758;galactosyltransferase activity#GO:0008378;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=21699|UniProtKB=Q49MI3 Q49MI3 CERKL PTHR12358:SF26 SPHINGOSINE KINASE CERAMIDE KINASE-LIKE PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 HUMAN|HGNC=710|UniProtKB=P36575 P36575 ARR3 PTHR11792:SF19 ARRESTIN ARRESTIN-C protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;receptor internalization#GO:0031623;membrane organization#GO:0061024;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;endocytosis#GO:0006897;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;sensory perception#GO:0007600 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>beta-ARR1#P05925;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880;Wnt signaling pathway#P00057>beta-arrestin#P01456;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723 HUMAN|HGNC=27346|UniProtKB=Q5VV17 Q5VV17 OTUD1 PTHR12419:SF11 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081 HUMAN|HGNC=626|UniProtKB=P07741 P07741 APRT PTHR32315:SF3 ADENINE PHOSPHORIBOSYLTRANSFERASE ADENINE PHOSPHORIBOSYLTRANSFERASE cation binding#GO:0043169;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity, transferring glycosyl groups#GO:0016757;ion binding#GO:0043167;anion binding#GO:0043168 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase metabolic process#GO:0009112;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;pigment biosynthetic process#GO:0046148;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;AMP metabolic process#GO:0046033;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase biosynthetic process#GO:0009113;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transferase#PC00220 Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphoribosyl transferase#P02810 HUMAN|HGNC=6943|UniProtKB=Q07820 Q07820 MCL1 PTHR11256:SF46 BCL-2 RELATED INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1 identical protein binding#GO:0042802;protein binding#GO:0005515;protein homodimerization activity#GO:0042803;binding#GO:0005488 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;cell death#GO:0008219;intracellular signal transduction#GO:0035556;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;negative regulation of cell death#GO:0060548;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of intrinsic apoptotic signaling pathway#GO:2001242;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>Mcl1#P00308;CCKR signaling map#P06959>MCL1#G07275;CCKR signaling map#P06959>MCL1#G06982 HUMAN|HGNC=34431|UniProtKB=Q5I0X4 Q5I0X4 C6orf226 PTHR40657:SF1 HYPOTHETICAL PROTEIN LOC681367 HYPOTHETICAL PROTEIN LOC681367 HUMAN|HGNC=26359|UniProtKB=A1KZ92 A1KZ92 PXDNL PTHR11475:SF38 OXIDASE/PEROXIDASE PEROXIDASIN-LIKE PROTEIN oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180 HUMAN|HGNC=16952|UniProtKB=Q9H3M7 Q9H3M7 TXNIP PTHR11188:SF14 ARRESTIN DOMAIN CONTAINING PROTEIN THIOREDOXIN-INTERACTING PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=4591|UniProtKB=Q9NRY4 Q9NRY4 ARHGAP35 PTHR46005:SF1 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 35 GTPase-activating protein#PC00257 HUMAN|HGNC=6412|UniProtKB=P04264 P04264 KRT1 PTHR45616:SF33 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 1 HUMAN|HGNC=16122|UniProtKB=Q9H4H8 Q9H4H8 FAM83D PTHR16181:SF21 UNCHARACTERIZED PROTEIN FAM83D cellular localization#GO:0051641;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;TOR signaling#GO:0031929;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular macromolecule localization#GO:0070727;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of phosphorylation#GO:0042325;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of cell cycle process#GO:0090068;protein localization to organelle#GO:0033365;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;ERK1 and ERK2 cascade#GO:0070371;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;protein localization to cytoskeleton#GO:0044380;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;spindle pole#GO:0000922;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229 HUMAN|HGNC=29280|UniProtKB=Q9P278 Q9P278 FNIP2 PTHR21634:SF11 UNCHARACTERIZED FOLLICULIN-INTERACTING PROTEIN 2 pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme inhibitor activity#GO:0004857;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234;chaperone binding#GO:0051087;ATPase activity#GO:0016887 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=29297|UniProtKB=Q6P9A1 Q6P9A1 ZNF530 PTHR24377:SF616 IP01015P-RELATED ZINC FINGER PROTEIN 530 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8323|UniProtKB=Q96R09 Q96R09 OR5B2 PTHR48018:SF116 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5B2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=11878|UniProtKB=Q9NRS4 Q9NRS4 TMPRSS4 PTHR24253:SF31 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 4 serine protease#PC00203 HUMAN|HGNC=25072|UniProtKB=Q5MNZ6 Q5MNZ6 WDR45B PTHR11227:SF18 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 3 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy of nucleus#GO:0044804;autophagy#GO:0006914 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;whole membrane#GO:0098805 HUMAN|HGNC=26801|UniProtKB=Q8N8Q8 Q8N8Q8 COX18 PTHR12428:SF51 OXA1 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;mitochondrial respiratory chain complex assembly#GO:0033108;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;cytochrome complex assembly#GO:0017004;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;mitochondrial cytochrome c oxidase assembly#GO:0033617;protein insertion into membrane#GO:0051205;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein localization to membrane#GO:0072657;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 transporter#PC00227 HUMAN|HGNC=17852|UniProtKB=Q8WUD6 Q8WUD6 CHPT1 PTHR10414:SF32 ETHANOLAMINEPHOSPHOTRANSFERASE CHOLINEPHOSPHOTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=1224|UniProtKB=O15165 O15165 LDLRAD4 PTHR16514:SF4 LOW DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING 4A LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 4 SMAD binding#GO:0046332;protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;regulation of cellular component organization#GO:0051128;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of cellular component organization#GO:0051129;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein-containing complex assembly#GO:0065003;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;response to endogenous stimulus#GO:0009719;regulation of protein-containing complex assembly#GO:0043254;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cellular response to transforming growth factor beta stimulus#GO:1903844;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of transforming growth factor beta receptor signaling pathway#GO:0030512;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=35464|UniProtKB=A6NIY4 A6NIY4 SPDYE5 PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=14186|UniProtKB=O00110 O00110 OVOL3 PTHR10032:SF220 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS TRANSCRIPTION FACTOR OVO-LIKE PROTEIN 3-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;epithelium development#GO:0060429;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;epidermis development#GO:0008544;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;epidermal cell differentiation#GO:0009913;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=17765|UniProtKB=Q8WVD3 Q8WVD3 RNF138 PTHR46968:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF138 E3 UBIQUITIN-PROTEIN LIGASE RNF138 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=24217|UniProtKB=Q86X95 Q86X95 CIR1 PTHR13151:SF2 CBF1 INTERACTING COREPRESSOR CIR COREPRESSOR INTERACTING WITH RBPJ 1 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 Notch signaling pathway#P00045>CoR#P01112 HUMAN|HGNC=10344|UniProtKB=P42766 P42766 RPL35 PTHR45722:SF9 60S RIBOSOMAL PROTEIN L35 60S RIBOSOMAL PROTEIN L35 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=20959|UniProtKB=Q9UPN6 Q9UPN6 SCAF8 PTHR15921:SF7 PRE-MRNA CLEAVAGE COMPLEX II SR-RELATED AND CTD-ASSOCIATED FACTOR 8 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;organic cyclic compound binding#GO:0097159;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;enzyme binding#GO:0019899;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;protein binding#GO:0005515;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA 3'-end processing#GO:0031124;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA polyadenylation#GO:0006378;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA processing#GO:0006397;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=37491|UniProtKB=F8W0I5 F8W0I5 NPIPB12 PTHR15438:SF5 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER B11-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4582|UniProtKB=Q16099 Q16099 GRIK4 PTHR18966:SF171 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 4 amino acid binding#GO:0016597;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;molecular transducer activity#GO:0060089;ion binding#GO:0043167;anion binding#GO:0043168;sodium channel activity#GO:0005272;glutamate binding#GO:0016595;signaling receptor activity#GO:0038023;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;monovalent inorganic cation transmembrane transporter activity#GO:0015077;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;transporter activity#GO:0005215;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA4#P01001;Ionotropic glutamate receptor pathway#P00037>KA#P01026;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Huntington disease#P00029>Kainate receptor#P00796 HUMAN|HGNC=15890|UniProtKB=Q9BY42 Q9BY42 RTF2 PTHR12775:SF0 PROTEIN C20ORF43 HOMOLOG REPLICATION TERMINATION FACTOR 2 cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;reproductive process#GO:0022414;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;regulation of reproductive process#GO:2000241;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;DNA biosynthetic process#GO:0071897;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=7452|UniProtKB=Q9NYA4 Q9NYA4 MTMR4 PTHR10807:SF64 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 4 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;regulation of cellular catabolic process#GO:0031329;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=1595|UniProtKB=Q14094 Q14094 CCNI PTHR10177:SF187 CYCLINS CYCLIN-I cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 HUMAN|HGNC=6925|UniProtKB=P02686 P02686 MBP PTHR11429:SF0 MYELIN BASIC PROTEIN MYELIN BASIC PROTEIN myelin protein#PC00161 HUMAN|HGNC=30939|UniProtKB=Q86UP3 Q86UP3 ZFHX4 PTHR45891:SF2 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28497|UniProtKB=Q8N4L1 Q8N4L1 TMEM151A PTHR31893:SF3 TRANSMEMBRANE PROTEIN 151 HOMOLOG TRANSMEMBRANE PROTEIN 151A HUMAN|HGNC=35458|UniProtKB=A6NHQ2 A6NHQ2 FBLL1 PTHR10335:SF6 RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN RRNA/TRNA 2'-O-METHYLTRANSFERASE FIBRILLARIN-LIKE PROTEIN 1 N-methyltransferase activity#GO:0008170;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;histone methylation#GO:0016571;protein modification process#GO:0036211;nucleobase-containing compound metabolic process#GO:0006139;protein alkylation#GO:0008213;ncRNA metabolic process#GO:0034660;protein methylation#GO:0006479;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;histone modification#GO:0016570;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;chromatin organization#GO:0006325;RNA methylation#GO:0001510 small nucleolar ribonucleoprotein complex#GO:0005732;membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684 RNA processing factor#PC00147 HUMAN|HGNC=29430|UniProtKB=Q5HYW3 Q5HYW3 RTL5 PTHR15503:SF2 LDOC1 RELATED RETROTRANSPOSON GAG-LIKE PROTEIN 5 HUMAN|HGNC=6134|UniProtKB=P56199 P56199 ITGA1 PTHR23220:SF22 INTEGRIN ALPHA INTEGRIN ALPHA-1 integrin#PC00126 Gonadotropin-releasing hormone receptor pathway#P06664>alpha-beta integrin dimer#P06820;Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=33872|UniProtKB=Q6UXD1 Q6UXD1 HRCT1 PTHR23009:SF2 UNCHARACTERIZED HISTIDINE-RICH CARBOXYL TERMINUS PROTEIN 1 HUMAN|HGNC=16887|UniProtKB=Q13113 Q13113 PDZK1IP1 PTHR15296:SF0 MEMBRANE-ASSOCIATED PROTEIN MAP17 PDZK1-INTERACTING PROTEIN 1 HUMAN|HGNC=28424|UniProtKB=Q9BQ61 Q9BQ61 TRIR PTHR34753:SF1 TELOMERASE RNA COMPONENT INTERACTING RNASE TELOMERASE RNA COMPONENT INTERACTING RNASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;RNA phosphodiester bond hydrolysis#GO:0090501;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA metabolism protein#PC00009 HUMAN|HGNC=25588|UniProtKB=Q96FL8 Q96FL8 SLC47A1 PTHR11206:SF73 MULTIDRUG RESISTANCE PROTEIN MULTIDRUG AND TOXIN EXTRUSION PROTEIN 1 transmembrane transporter activity#GO:0022857;xenobiotic transmembrane transporter activity#GO:0042910;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;cation transport#GO:0006812;establishment of localization#GO:0051234;organic cation transport#GO:0015695;ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=26494|UniProtKB=Q96MN5 Q96MN5 TCEANC2 PTHR11477:SF14 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A N-TERMINAL AND CENTRAL DOMAIN-CONTAINING PROTEIN 2 general transcription factor#PC00259 HUMAN|HGNC=18296|UniProtKB=Q9NY27 Q9NY27 PPP4R2 PTHR16487:SF2 PPP4R2-RELATED PROTEIN SERINE/THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6612|UniProtKB=Q9UGP4 Q9UGP4 LIMD1 PTHR24219:SF3 LIM DOMAIN-CONTAINING PROTEIN JUB LIM DOMAIN-CONTAINING PROTEIN 1 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;post-transcriptional gene silencing by RNA#GO:0035194;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;response to decreased oxygen levels#GO:0036293;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;posttranscriptional gene silencing#GO:0016441;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to hypoxia#GO:0001666;RNA metabolic process#GO:0016070;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;response to oxygen levels#GO:0070482;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;gene silencing by miRNA#GO:0035195;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;gene silencing by RNA#GO:0031047;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;hippo signaling#GO:0035329;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 supramolecular complex#GO:0099080;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912 transcription cofactor#PC00217 HUMAN|HGNC=26120|UniProtKB=Q8N0V3 Q8N0V3 RBFA PTHR14725:SF0 UNCHARACTERIZED RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED HUMAN|HGNC=18178|UniProtKB=Q9UK41 Q9UK41 VPS28 PTHR12937:SF0 VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG protein-containing complex binding#GO:0044877;binding#GO:0005488 protein catabolic process in the vacuole#GO:0007039;endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;multivesicular body sorting pathway#GO:0071985;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular macromolecule localization#GO:0070727;cellular protein catabolic process#GO:0044257;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=10383|UniProtKB=P46783 P46783 RPS10 PTHR12146:SF10 40S RIBOSOMAL PROTEIN S10 40S RIBOSOMAL PROTEIN S10 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;ribonucleoprotein complex subunit organization#GO:0071826;ribonucleoprotein complex assembly#GO:0022618;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;ribosome biogenesis#GO:0042254;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=5748|UniProtKB=P01601 P01601 IGKV1D-16 PTHR23267:SF460 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1D-16 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=22201|UniProtKB=Q9Y4C2 Q9Y4C2 TCAF1 PTHR15730:SF1 EXPERIMENTAL AUTOIMMUNE PROSTATITIS ANTIGEN 2-RELATED TRPM8 CHANNEL-ASSOCIATED FACTOR 1 positive regulation of ion transport#GO:0043270;regulation of transmembrane transport#GO:0034762;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;positive regulation of molecular function#GO:0044093;positive regulation of ion transmembrane transporter activity#GO:0032414;regulation of localization#GO:0032879;positive regulation of transport#GO:0051050;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;regulation of ion transmembrane transporter activity#GO:0032412;anion transmembrane transport#GO:0098656;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;positive regulation of transporter activity#GO:0032411;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;positive regulation of ion transmembrane transport#GO:0034767;anion transport#GO:0006820;biological regulation#GO:0065007;positive regulation of transmembrane transport#GO:0034764;regulation of ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;inorganic anion transport#GO:0015698 HUMAN|HGNC=869|UniProtKB=Q04656 Q04656 ATP7A PTHR43520:SF8 ATP7, ISOFORM B COPPER-TRANSPORTING ATPASE 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 primary active transporter#PC00068 HUMAN|HGNC=17481|UniProtKB=O43164 O43164 PJA2 PTHR15710:SF5 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE PRAJA-2 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=29874|UniProtKB=Q6I9Y2 Q6I9Y2 THOC7 PTHR23405:SF5 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED THO COMPLEX SUBUNIT 7 HOMOLOG cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14781|UniProtKB=Q8NGH5 Q8NGH5 OR56A1 PTHR24248:SF62 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 56A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=19711|UniProtKB=Q96F81 Q96F81 DISP1 PTHR45951:SF4 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED HOMOLOG 1 HUMAN|HGNC=21221|UniProtKB=Q96NJ5 Q96NJ5 KLHL32 PTHR45632:SF16 LD33804P KELCH-LIKE PROTEIN 32 HUMAN|HGNC=29994|UniProtKB=Q6ZWK6 Q6ZWK6 TMPRSS11F PTHR24253:SF65 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11F serine protease#PC00203 HUMAN|HGNC=25163|UniProtKB=Q8N1L9 Q8N1L9 BATF2 PTHR23351:SF11 FOS TRANSCRIPTION FACTOR-RELATED BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=593|UniProtKB=O15392 O15392 BIRC5 PTHR10044:SF139 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease inhibitor#PC00191 Angiogenesis#P00005>Survivin#P00198 HUMAN|HGNC=26260|UniProtKB=Q8N614 Q8N614 TMEM156 PTHR14788:SF5 TRANSMEMBRANE PROTEIN 156 TRANSMEMBRANE PROTEIN 156 HUMAN|HGNC=30941|UniProtKB=Q8N5P1 Q8N5P1 ZC3H8 PTHR13119:SF32 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 8 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244 HUMAN|HGNC=6812|UniProtKB=O60732 O60732 MAGEC1 PTHR11736:SF17 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN C1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17083|UniProtKB=Q15050 Q15050 RRS1 PTHR17602:SF4 RIBOSOME BIOGENESIS REGULATORY PROTEIN RIBOSOME BIOGENESIS REGULATORY PROTEIN HOMOLOG cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;rRNA processing#GO:0006364;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;ncRNA metabolic process#GO:0034660;ncRNA processing#GO:0034470;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;ribosome biogenesis#GO:0042254;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;rRNA metabolic process#GO:0016072;protein transport#GO:0015031;intracellular transport#GO:0046907;maturation of SSU-rRNA#GO:0030490;protein-containing complex localization#GO:0031503;cellular aromatic compound metabolic process#GO:0006725;ribosomal subunit export from nucleus#GO:0000054;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;RNA processing#GO:0006396;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex export from nucleus#GO:0071426;amide transport#GO:0042886;organic substance transport#GO:0071702;organic cyclic compound metabolic process#GO:1901360;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;protein export from nucleus#GO:0006611;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;cleavage involved in rRNA processing#GO:0000469;heterocycle metabolic process#GO:0046483;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex localization#GO:0071166;cellular process#GO:0009987;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;ribonucleoprotein complex biogenesis#GO:0022613;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;endonucleolytic cleavage involved in rRNA processing#GO:0000478;RNA export from nucleus#GO:0006405;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684 ribosomal protein#PC00202 HUMAN|HGNC=25480|UniProtKB=Q9NWC5 Q9NWC5 TMEM45A PTHR16007:SF21 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45A HUMAN|Ensembl=ENSG00000283526|UniProtKB=A0A1B0GWB2 A0A1B0GWB2 PRRT1B PTHR14948:SF18 NG5 PROLINE RICH TRANSMEMBRANE PROTEIN 1B cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=8109|UniProtKB=P11926 P11926 ODC1 PTHR11482:SF42 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;ornithine decarboxylase activity#GO:0004586;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053;CCKR signaling map#P06959>ODC1#P07221;CCKR signaling map#P06959>ODC1#G06989 HUMAN|HGNC=9679|UniProtKB=Q9UMZ3 Q9UMZ3 PTPRQ PTHR46957:SF1 CYTOKINE RECEPTOR PHOSPHATIDYLINOSITOL PHOSPHATASE PTPRQ transmembrane signal receptor#PC00197 HUMAN|HGNC=12931|UniProtKB=Q15072 Q15072 ZNF146 PTHR24377:SF732 IP01015P-RELATED ZINC FINGER PROTEIN OZF cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19060|UniProtKB=Q8TDV5 Q8TDV5 GPR119 PTHR22750:SF7 G-PROTEIN COUPLED RECEPTOR GLUCOSE-DEPENDENT INSULINOTROPIC RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;phosphatidylcholine binding#GO:0031210;binding#GO:0005488;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;phospholipid binding#GO:0005543;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=26019|UniProtKB=Q9NX62 Q9NX62 BPNT2 PTHR43028:SF6 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 GOLGI-RESIDENT ADENOSINE 3',5'-BISPHOSPHATE 3'-PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;nucleotidase activity#GO:0008252 multicellular organismal process#GO:0032501;system development#GO:0048731;skeletal system development#GO:0001501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=28870|UniProtKB=Q9P1T7 Q9P1T7 MDFIC PTHR15304:SF0 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=15372|UniProtKB=Q8NGB9 Q8NGB9 OR4F6 PTHR48002:SF122 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4F6 transmembrane signal receptor#PC00197 HUMAN|HGNC=17094|UniProtKB=Q96EH5 Q96EH5 RPL39L PTHR19970:SF22 RIBOSOMAL PROTEIN L39E 60S RIBOSOMAL PROTEIN L39-LIKE cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=11848|UniProtKB=O60603 O60603 TLR2 PTHR24365:SF17 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;pattern recognition receptor signaling pathway#GO:0002221;cellular process#GO:0009987;defense response#GO:0006952;signaling#GO:0023052;inflammatory response#GO:0006954 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR1,2,6#P01380;Toll receptor signaling pathway#P00054>TLR#P01346 HUMAN|HGNC=3755|UniProtKB=O75369 O75369 FLNB PTHR38537:SF7 JITTERBUG, ISOFORM N FILAMIN-B Integrin signalling pathway#P00034>Filamin#P00914 HUMAN|HGNC=18026|UniProtKB=Q9BYX2 Q9BYX2 TBC1D2 PTHR22957:SF570 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 2A GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=24475|UniProtKB=Q9UI17 Q9UI17 DMGDH PTHR13847:SF187 SARCOSINE DEHYDROGENASE-RELATED DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 HUMAN|HGNC=13667|UniProtKB=Q9BXS5 Q9BXS5 AP1M1 PTHR10529:SF257 AP COMPLEX SUBUNIT MU AP-1 COMPLEX SUBUNIT MU-1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 HUMAN|HGNC=11657|UniProtKB=Q8TDR4 Q8TDR4 TCP10L PTHR10331:SF25 T COMPLEX PROTEIN 10 T-COMPLEX PROTEIN 10A HOMOLOG 1-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;nitrogen compound transport#GO:0071705;centrosome duplication#GO:0051298;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;peptide transport#GO:0015833;microtubule organizing center organization#GO:0031023;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;centriole replication#GO:0007099;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=4430|UniProtKB=O95249 O95249 GOSR1 PTHR21094:SF2 GOS-28 SNARE- RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle targeting, to, from or within Golgi#GO:0048199;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;vesicle organization#GO:0016050;establishment of organelle localization#GO:0051656;organelle fusion#GO:0048284;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;SNARE complex#GO:0031201;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 SNARE protein#PC00034 HUMAN|HGNC=6867|UniProtKB=Q9Y4K4 Q9Y4K4 MAP4K5 PTHR48012:SF19 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 5 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;MAP kinase kinase activity#GO:0004708;protein kinase activity#GO:0004672 Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCK#P00268 HUMAN|HGNC=16651|UniProtKB=Q9BRJ2 Q9BRJ2 MRPL45 PTHR28554:SF1 39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ribosomal protein#PC00202 HUMAN|HGNC=15917|UniProtKB=Q9NQ66 Q9NQ66 PLCB1 PTHR10336:SF12 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;phospholipase C activity#GO:0004629;calmodulin binding#GO:0005516;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;system process#GO:0003008;behavior#GO:0007610;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cognition#GO:0050890;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;multicellular organismal process#GO:0032501;intracellular signal transduction#GO:0035556;signaling#GO:0023052 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 phospholipase#PC00186 CCKR signaling map#P06959>PLC_beta#P07110;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Gonadotropin-releasing hormone receptor pathway#P06664>PLCbeta#P06705;Endogenous cannabinoid signaling#P05730>PLC#P05746;Endothelin signaling pathway#P00019>PLCbeta#P00591;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484 HUMAN|HGNC=12630|UniProtKB=Q93009 Q93009 USP7 PTHR24006:SF761 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;regulation of protein stability#GO:0031647;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=26026|UniProtKB=Q9NX45 Q9NX45 SOHLH2 PTHR16223:SF16 TRANSCRIPTION FACTOR BHLH83-RELATED SPERMATOGENESIS- AND OOGENESIS-SPECIFIC BASIC HELIX-LOOP-HELIX-CONTAINING PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=26675|UniProtKB=Q8NA31 Q8NA31 TERB1 PTHR14014:SF0 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 1 TELOMERE REPEATS-BINDING BOUQUET FORMATION PROTEIN 1 cellular localization#GO:0051641;organelle localization#GO:0051640;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;chromosome segregation#GO:0007059;M phase#GO:0000279;chromosome organization involved in meiotic cell cycle#GO:0070192;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle phase#GO:0022403;establishment of organelle localization#GO:0051656;meiosis I#GO:0007127;meiosis I cell cycle phase#GO:0098764;nuclear chromosome segregation#GO:0098813;establishment of chromosome localization#GO:0051303;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;biological phase#GO:0044848;chromosome localization#GO:0050000 nuclear telomere cap complex#GO:0000783;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781;protein-DNA complex#GO:0032993;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4717|UniProtKB=P16402 P16402 H1-3 PTHR11467:SF137 HISTONE H1 HISTONE H1.3 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of chromatin silencing#GO:0031935;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of chromatin silencing#GO:0031936;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of chromatin organization#GO:1902275;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;chromosome condensation#GO:0030261;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of DNA recombination#GO:0000018;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone#PC00118 HUMAN|HGNC=26144|UniProtKB=Q86YC2 Q86YC2 PALB2 PTHR14662:SF2 PARTNER AND LOCALIZER OF BRCA2 PARTNER AND LOCALIZER OF BRCA2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=13375|UniProtKB=Q9H2W1 Q9H2W1 MS4A6A PTHR23320:SF135 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 6A transporter#PC00227 HUMAN|HGNC=846|UniProtKB=P56385 P56385 ATP5ME PTHR12427:SF1 ATP SYNTHASE E CHAIN, MITOCHONDRIAL ATP SYNTHASE SUBUNIT E, MITOCHONDRIAL envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 HUMAN|HGNC=23813|UniProtKB=Q9BQI4 Q9BQI4 CCDC3 PTHR31663:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 COILED-COIL DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=25879|UniProtKB=Q8WXB4 Q8WXB4 ZNF606 PTHR24376:SF206 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 606 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15633|UniProtKB=Q9NR96 Q9NR96 TLR9 PTHR47410:SF3 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;defense response to virus#GO:0051607;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;response to virus#GO:0009615;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;tumor necrosis factor production#GO:0032640;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;pattern recognition receptor signaling pathway#GO:0002221;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR#P01346 HUMAN|Gene=SELV|UniProtKB=P59797 P59797 SELENOV PTHR15124:SF17 SELENOPROTEIN W SELENOPROTEIN V response to stimulus#GO:0050896;response to inorganic substance#GO:0010035;response to chemical#GO:0042221 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=23529|UniProtKB=Q8TEA1 Q8TEA1 NSUN6 PTHR22807:SF34 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(72)-C(5))-METHYLTRANSFERASE NSUN6 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=21145|UniProtKB=Q96D15 Q96D15 RCN3 PTHR10827:SF47 RETICULOCALBIN RETICULOCALBIN-3 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 calmodulin-related#PC00061 HUMAN|HGNC=8712|UniProtKB=Q9Y5G0 Q9Y5G0 PCDHGB5 PTHR24028:SF259 CADHERIN-87A PROTOCADHERIN GAMMA-B3-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=8995|UniProtKB=O14986 O14986 PIP5K1B PTHR23086:SF34 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 BETA kinase#PC00137 HUMAN|HGNC=12406|UniProtKB=P50607 P50607 TUB PTHR16517:SF20 TUBBY-RELATED TUBBY PROTEIN HOMOLOG localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;cellular protein localization#GO:0034613;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=4816|UniProtKB=P12081 P12081 HARS1 PTHR11476:SF8 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE, CYTOPLASMIC identical protein binding#GO:0042802;protein binding#GO:0005515;binding#GO:0005488 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=30038|UniProtKB=Q86XP0 Q86XP0 PLA2G4D PTHR10728:SF31 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 DELTA hydrolase activity, acting on ester bonds#GO:0016788;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;phospholipid binding#GO:0005543;carboxylic ester hydrolase activity#GO:0052689;cation binding#GO:0043169;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;hydrolase activity#GO:0016787;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phospholipase#PC00186 Angiogenesis#P00005>cPLA2#P00251 HUMAN|HGNC=11860|UniProtKB=Q9BZW5 Q9BZW5 TM6SF1 PTHR14568:SF10 TRANSMEMBRANE SUPERFAMILY 6 MEMBER 1/2 TRANSMEMBRANE 6 SUPERFAMILY MEMBER 1 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=28797|UniProtKB=Q6ZMB5 Q6ZMB5 TMEM184A PTHR23423:SF59 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184A localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=21464|UniProtKB=Q86W26 Q86W26 NLRP10 PTHR45690:SF4 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 10 HUMAN|HGNC=189|UniProtKB=O75078 O75078 ADAM11 PTHR11905:SF114 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 11 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=26525|UniProtKB=Q6P387 Q6P387 C16orf46 PTHR36869:SF1 CHROMOSOME 16 OPEN READING FRAME 46 CHROMOSOME 16 OPEN READING FRAME 46 HUMAN|HGNC=11918|UniProtKB=P43489 P43489 TNFRSF4 PTHR47881:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 4 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 4 transmembrane signal receptor#PC00197 HUMAN|HGNC=13705|UniProtKB=Q14656 Q14656 TMEM187 PTHR15066:SF0 TRANSMEMBRANE PROTEIN 187 TRANSMEMBRANE PROTEIN 187 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;plasma membrane#GO:0005886 HUMAN|HGNC=12782|UniProtKB=P56703 P56703 WNT3 PTHR12027:SF82 WNT RELATED PROTO-ONCOGENE WNT-3 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=4164|UniProtKB=P01350 P01350 GAST PTHR19309:SF0 GASTRIN GASTRIN peptide hormone#PC00179 CCKR signaling map#P06959>G34-Gly#P07036;CCKR signaling map#P06959>G17 - Gly#P07236;CCKR signaling map#P06959>G34#P07190;CCKR signaling map#P06959>Beta-arrestin-1/2#P07187;CCKR signaling map#P06959>G17#P07215 HUMAN|HGNC=19246|UniProtKB=Q9NYB0 Q9NYB0 TERF2IP PTHR16466:SF6 TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 telomeric DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;telomere maintenance via telomere lengthening#GO:0010833;regulation of nitrogen compound metabolic process#GO:0051171;telomere organization#GO:0032200;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;nuclear telomere cap complex#GO:0000783;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781;protein-DNA complex#GO:0032993;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=8782|UniProtKB=Q08493 Q08493 PDE4C PTHR11347:SF135 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4C hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 HUMAN|HGNC=25611|UniProtKB=Q567U6 Q567U6 CCDC93 PTHR16441:SF0 FIDIPIDINE COILED-COIL DOMAIN-CONTAINING PROTEIN 93 localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;Golgi to plasma membrane transport#GO:0006893 HUMAN|HGNC=14852|UniProtKB=Q8NGN0 Q8NGN0 OR4D5 PTHR48002:SF49 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D5 transmembrane signal receptor#PC00197 HUMAN|HGNC=54075|UniProtKB=A0A2R8YCJ5 A0A2R8YCJ5 SMIM41 PTHR28649:SF1 PROTEIN REPRIMO-RELATED SMALL INTEGRAL MEMBRANE PROTEIN 41 HUMAN|HGNC=9568|UniProtKB=Q06323 Q06323 PSME1 PTHR10660:SF5 PROTEASOME REGULATOR PA28 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 1 protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;proteasomal protein catabolic process#GO:0010498;regulation of G1/S transition of mitotic cell cycle#GO:2000045;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;cell cycle phase transition#GO:0044770;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;mitotic cell cycle phase transition#GO:0044772;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;positive regulation of catalytic activity#GO:0043085;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of mitotic cell cycle#GO:0007346 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12112|UniProtKB=A0A0A6YYK6 A0A0A6YYK6 TRAV16 PTHR19367:SF4 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 16 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=15680|UniProtKB=Q9NRC6 Q9NRC6 SPTBN5 PTHR23167:SF46 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5 HUMAN|HGNC=26825|UniProtKB=Q8N8F6 Q8N8F6 YIPF7 PTHR21236:SF5 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF7 HUMAN|HGNC=17448|UniProtKB=Q9H4D0 Q9H4D0 CLSTN2 PTHR14139:SF3 CALSYNTENIN CALSYNTENIN-2 cellular component biogenesis#GO:0044085;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;positive regulation of multicellular organismal process#GO:0051240 cell surface#GO:0009986;synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=29079|UniProtKB=O60341 O60341 KDM1A PTHR10742:SF373 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 HUMAN|HGNC=4542|UniProtKB=Q9BXA5 Q9BXA5 SUCNR1 PTHR24231:SF14 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR SUCCINATE RECEPTOR 1 G-protein coupled receptor#PC00021 HUMAN|HGNC=7909|UniProtKB=Q9UND3 Q9UND3 NPIPA1 PTHR15438:SF14 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER A1-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7896|UniProtKB=Q14207 Q14207 NPAT PTHR15087:SF14 PROTEIN NPAT PROTEIN NPAT molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25159|UniProtKB=A0PJX4 A0PJX4 SHISA3 PTHR31395:SF4 SHISA PROTEIN SHISA-3 HOMOLOG scaffold/adaptor protein#PC00226 HUMAN|HGNC=7550|UniProtKB=Q14324 Q14324 MYBPC2 PTHR13817:SF17 TITIN MYOSIN-BINDING PROTEIN C, FAST-TYPE HUMAN|HGNC=7707|UniProtKB=P28331 P28331 NDUFS1 PTHR11615:SF6 NITRATE, FORMATE, IRON DEHYDROGENASE NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL 4 iron, 4 sulfur cluster binding#GO:0051539;metal cluster binding#GO:0051540;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 dehydrogenase#PC00092 HUMAN|HGNC=16144|UniProtKB=Q8NC74 Q8NC74 RBBP8NL PTHR15107:SF3 RETINOBLASTOMA BINDING PROTEIN 8 RBBP8 N-TERMINAL-LIKE PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;single-stranded DNA binding#GO:0003697;endonuclease activity#GO:0004519;damaged DNA binding#GO:0003684;double-stranded DNA binding#GO:0003690;deoxyribonuclease activity#GO:0004536;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;endodeoxyribonuclease activity#GO:0004520 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;DNA double-strand break processing#GO:0000729;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;site of double-strand break#GO:0035861;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 HUMAN|HGNC=1704|UniProtKB=Q9UIB8 Q9UIB8 CD84 PTHR12080:SF103 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 5 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=10666|UniProtKB=Q9Y365 Q9Y365 STARD10 PTHR19308:SF7 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN START DOMAIN-CONTAINING PROTEIN 10 HUMAN|HGNC=37238|UniProtKB=Q6ZR85 Q6ZR85 C17orf107 PTHR38506:SF1 RIKEN CDNA 4930544D05 GENE RIKEN CDNA 4930544D05 GENE HUMAN|HGNC=28683|UniProtKB=Q8IYN2 Q8IYN2 TCEAL8 PTHR14754:SF11 TRANSCRIPTION ELONGATION FACTOR A TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 8 general transcription factor#PC00259 HUMAN|HGNC=6738|UniProtKB=O95372 O95372 LYPLA2 PTHR10655:SF13 LYSOPHOSPHOLIPASE-RELATED ACYL-PROTEIN THIOESTERASE 2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;macromolecule deacylation#GO:0098732;protein deacylation#GO:0035601;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;lipoprotein metabolic process#GO:0042157;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phospholipase#PC00186 HUMAN|HGNC=11198|UniProtKB=O15370 O15370 SOX12 PTHR10270:SF221 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-12 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=13597|UniProtKB=Q8N3Y1 Q8N3Y1 FBXW8 PTHR44019:SF11 WD REPEAT-CONTAINING PROTEIN 55 F-BOX/WD REPEAT-CONTAINING PROTEIN 8 HUMAN|HGNC=16290|UniProtKB=Q9UPN9 Q9UPN9 TRIM33 PTHR45915:SF3 TRANSCRIPTION INTERMEDIARY FACTOR E3 UBIQUITIN-PROTEIN LIGASE TRIM33 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=29279|UniProtKB=Q9P281 Q9P281 BAHCC1 PTHR12505:SF22 PHD FINGER TRANSCRIPTION FACTOR BAH AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 DNA-binding transcription factor#PC00218 HUMAN|HGNC=37217|UniProtKB=C9J1S8 C9J1S8 TRIM49D2 PTHR24103:SF661 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 49D ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=2254|UniProtKB=Q9ULV4 Q9ULV4 CORO1C PTHR10856:SF10 CORONIN CORONIN-1C cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular developmental process#GO:0048869;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;multicellular organism development#GO:0007275;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;actin filament-based process#GO:0030029;neural crest cell differentiation#GO:0014033;organelle organization#GO:0006996;mesenchyme development#GO:0060485;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;stem cell differentiation#GO:0048863;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 non-motor actin binding protein#PC00165 HUMAN|HGNC=14277|UniProtKB=Q9BYD2 Q9BYD2 MRPL9 PTHR21368:SF18 50S RIBOSOMAL PROTEIN L9 39S RIBOSOMAL PROTEIN L9, MITOCHONDRIAL ribosomal protein#PC00202 HUMAN|HGNC=24593|UniProtKB=Q9H2H0 Q9H2H0 CXXC4 PTHR13419:SF1 ZINC FINGER-CONTAINING CXXC-TYPE ZINC FINGER PROTEIN 4 cation binding#GO:0043169;sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;organic cyclic compound binding#GO:0097159;transition metal ion binding#GO:0046914;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;metal ion binding#GO:0046872;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167 regulation of biological process#GO:0050789;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=21030|UniProtKB=Q53QZ3 Q53QZ3 ARHGAP15 PTHR23176:SF108 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 15 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=31982|UniProtKB=Q4UJ75 Q4UJ75 ANKRD20A4P PTHR24147:SF1 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 20A1-RELATED HUMAN|HGNC=33995|UniProtKB=A0A0B4J2A2 A0A0B4J2A2 PPIAL4C PTHR11071:SF466 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A-LIKE 4C-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=3702|UniProtKB=Q13642 Q13642 FHL1 PTHR47029:SF4 FOUR AND A HALF LIM DOMAINS PROTEIN 1 FOUR AND A HALF LIM DOMAINS PROTEIN 1 ion channel binding#GO:0044325;protein binding#GO:0005515;binding#GO:0005488 HUMAN|HGNC=26579|UniProtKB=Q6UXU6 Q6UXU6 TMEM92 PTHR31359:SF31 TRANSMEMBRANE PROTEIN 92 TRANSMEMBRANE PROTEIN 92 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3516|UniProtKB=Q9UBQ6 Q9UBQ6 EXTL2 PTHR11062:SF338 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-2-RELATED glycosyltransferase#PC00111 HUMAN|HGNC=24511|UniProtKB=Q9Y3Y2 Q9Y3Y2 CHTOP PTHR19965:SF22 RNA AND EXPORT FACTOR BINDING PROTEIN CHROMATIN TARGET OF PRMT1 PROTEIN RNA metabolism protein#PC00031 HUMAN|HGNC=14272|UniProtKB=Q8IUH2 Q8IUH2 CREG2 PTHR13343:SF15 CREG1 PROTEIN PROTEIN CREG2 HUMAN|HGNC=4318|UniProtKB=P10070 P10070 GLI2 PTHR45718:SF6 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLI2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690 HUMAN|HGNC=25564|UniProtKB=Q9NVJ2 Q9NVJ2 ARL8B PTHR45732:SF13 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8B bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=11167|UniProtKB=Q13424 Q13424 SNTA1 PTHR10554:SF6 SYNTROPHIN ALPHA-1-SYNTROPHIN membrane protein complex#GO:0098796;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886;sarcolemma#GO:0042383 HUMAN|HGNC=6254|UniProtKB=Q8NCM2 Q8NCM2 KCNH5 PTHR10217:SF533 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 5 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=1233|UniProtKB=P81408 P81408 FAM189B PTHR17615:SF7 PROTEIN FAM189A PROTEIN FAM189B HUMAN|HGNC=2468|UniProtKB=Q9UQE7 Q9UQE7 SMC3 PTHR43977:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 HUMAN|HGNC=21899|UniProtKB=Q674R7 Q674R7 ATG9B PTHR13038:SF14 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9B cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;autophagy of mitochondrion#GO:0000422;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle disassembly#GO:1903008;protein localization#GO:0008104;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;autophagy of nucleus#GO:0044804;autophagy#GO:0006914 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229 HUMAN|HGNC=22964|UniProtKB=Q9Y2W1 Q9Y2W1 THRAP3 PTHR15268:SF16 THRAP3/BCLAF1 THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN 3 nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=25110|UniProtKB=Q9BRP7 Q9BRP7 FDXACB1 PTHR11538:SF26 PHENYLALANYL-TRNA SYNTHETASE FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1 catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;cellular amino acid metabolic process#GO:0006520;RNA methylation#GO:0001510;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=6399|UniProtKB=O60684 O60684 KPNA6 PTHR23316:SF8 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-7 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=24484|UniProtKB=Q9NVH2 Q9NVH2 INTS7 PTHR13322:SF2 C1ORF73 PROTEIN INTEGRATOR COMPLEX SUBUNIT 7 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 HUMAN|HGNC=17825|UniProtKB=P53816 P53816 PLAAT3 PTHR13943:SF31 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 3 transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9070|UniProtKB=P08567 P08567 PLEK PTHR12092:SF1 PLECKSTRIN PLECKSTRIN cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actin cytoskeleton reorganization#GO:0031532;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=11086|UniProtKB=O94813 O94813 SLIT2 PTHR45836:SF2 SLIT HOMOLOG SLIT HOMOLOG 2 PROTEIN carbohydrate derivative binding#GO:0097367;binding#GO:0005488;heparin binding#GO:0008201;protein binding#GO:0005515;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;growth#GO:0040007;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;regulation of cell growth#GO:0001558;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cell growth#GO:0016049;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 HUMAN|HGNC=6014|UniProtKB=P05112 P05112 IL4 PTHR47401:SF1 INTERLEUKIN-4 INTERLEUKIN-4 binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102 positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;activation of immune response#GO:0002253;positive regulation of signal transduction#GO:0009967;organelle membrane fusion#GO:0090174;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;lymphocyte mediated immunity#GO:0002449;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;peptidyl-tyrosine phosphorylation#GO:0018108;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;positive regulation of receptor signaling pathway via STAT#GO:1904894;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;somatic diversification of immune receptors#GO:0002200;establishment of organelle localization#GO:0051656;leukocyte activation#GO:0045321;negative regulation of cell migration#GO:0030336;lymphocyte activation involved in immune response#GO:0002285;negative regulation of locomotion#GO:0040013;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;localization of cell#GO:0051674;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;regulation of macroautophagy#GO:0016241;positive regulation of lymphocyte mediated immunity#GO:0002708;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;cell activation#GO:0001775;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;type 2 immune response#GO:0042092;anatomical structure development#GO:0048856;regulation of defense response#GO:0031347;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of receptor-mediated endocytosis#GO:0048259;taxis#GO:0042330;regulation of locomotion#GO:0040012;RNA metabolic process#GO:0016070;regulation of signaling#GO:0023051;hematopoietic or lymphoid organ development#GO:0048534;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;leukocyte cell-cell adhesion#GO:0007159;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;muscle structure development#GO:0061061;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;somatic cell DNA recombination#GO:0016444;negative regulation of programmed cell death#GO:0043069;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of cell motility#GO:2000147;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of chemotaxis#GO:0050920;cell death#GO:0008219;regulation of immune system process#GO:0002682;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;immune effector process#GO:0002252;signaling#GO:0023052;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;nucleic acid-templated transcription#GO:0097659;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;positive regulation of catalytic activity#GO:0043085;immune response#GO:0006955;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cell motility#GO:0048870;positive regulation of cellular biosynthetic process#GO:0031328;cell-cell fusion#GO:0140253;organic cyclic compound biosynthetic process#GO:1901362;anatomical structure formation involved in morphogenesis#GO:0048646;negative regulation of cell activation#GO:0050866;positive regulation of protein metabolic process#GO:0051247;syncytium formation by plasma membrane fusion#GO:0000768;membrane fusion#GO:0061025;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;response to other organism#GO:0051707;positive regulation of cellular component organization#GO:0051130;regulation of cell death#GO:0010941;positive regulation of kinase activity#GO:0033674;negative regulation of lymphocyte activation#GO:0051250;response to external biotic stimulus#GO:0043207;regulation of protein modification process#GO:0031399;plasma membrane fusion#GO:0045026;muscle cell differentiation#GO:0042692;regulation of catabolic process#GO:0009894;membrane organization#GO:0061024;regulation of cell-cell adhesion#GO:0022407;positive regulation of cellular metabolic process#GO:0031325;negative regulation of inflammatory response#GO:0050728;regulation of RNA biosynthetic process#GO:2001141;regulation of T cell activation#GO:0050863;positive regulation of cellular component movement#GO:0051272;regulation of vesicle-mediated transport#GO:0060627;positive regulation of leukocyte activation#GO:0002696;regulation of cell activation#GO:0050865;regulation of phosphorus metabolic process#GO:0051174;regulated exocytosis#GO:0045055;leukocyte migration#GO:0050900;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of secretion#GO:0051046;regulation of leukocyte cell-cell adhesion#GO:1903037;apoptotic process#GO:0006915;leukocyte chemotaxis#GO:0030595;organic substance metabolic process#GO:0071704;regulation of endocytosis#GO:0030100;macromolecule metabolic process#GO:0043170;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;positive regulation of secretion#GO:0051047;positive regulation of locomotion#GO:0040017;positive regulation of transport#GO:0051050;positive regulation of T cell differentiation#GO:0045582;regulation of cellular localization#GO:0060341;positive regulation of cellular process#GO:0048522;negative regulation of cell adhesion#GO:0007162;positive regulation of phosphate metabolic process#GO:0045937;regulation of cytokine biosynthetic process#GO:0042035;regulation of production of molecular mediator of immune response#GO:0002700;aromatic compound biosynthetic process#GO:0019438;positive regulation of autophagy#GO:0010508;locomotion#GO:0040011;regulation of cellular metabolic process#GO:0031323;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;response to virus#GO:0009615;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;regulation of phosphate metabolic process#GO:0019220;tumor necrosis factor production#GO:0032640;humoral immune response#GO:0006959;negative regulation of cell-cell adhesion#GO:0022408;developmental process#GO:0032502;transport#GO:0006810;positive regulation of cellular catabolic process#GO:0031331;regulation of cell differentiation#GO:0045595;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;granulocyte chemotaxis#GO:0071621;positive regulation of metabolic process#GO:0009893;positive regulation of leukocyte mediated immunity#GO:0002705;hemopoiesis#GO:0030097;receptor-mediated endocytosis#GO:0006898;regulation of gene expression#GO:0010468;regulation of lymphocyte activation#GO:0051249;receptor signaling pathway via JAK-STAT#GO:0007259;cellular catabolic process#GO:0044248;myeloid cell differentiation#GO:0030099;regulation of cytokine production#GO:0001817;regulation of response to external stimulus#GO:0032101;positive regulation of cell differentiation#GO:0045597;regulation of apoptotic process#GO:0042981;regulation of autophagy#GO:0010506;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;T cell mediated immunity#GO:0002456;organic substance biosynthetic process#GO:1901576;regulation of RNA metabolic process#GO:0051252;positive regulation of developmental process#GO:0051094;negative regulation of apoptotic process#GO:0043066;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular protein metabolic process#GO:0032268;regulation of leukocyte activation#GO:0002694;positive regulation of protein kinase activity#GO:0045860;extrinsic apoptotic signaling pathway#GO:0097191;T cell activation#GO:0042110;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of response to external stimulus#GO:0032102;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477;positive regulation of cell-cell adhesion#GO:0022409;DNA metabolic process#GO:0006259;organelle localization#GO:0051640;macroautophagy#GO:0016236;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of lymphocyte activation#GO:0051251;production of molecular mediator of immune response#GO:0002440;membrane invagination#GO:0010324;secretion#GO:0046903;innate immune response#GO:0045087;regulation of adaptive immune response#GO:0002819;negative regulation of cell motility#GO:2000146;defense response#GO:0006952;negative regulation of cell communication#GO:0010648;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell adhesion#GO:0007155;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;tyrosine phosphorylation of STAT protein#GO:0007260;negative regulation of leukocyte activation#GO:0002695;primary metabolic process#GO:0044238;negative regulation of cell death#GO:0060548;apoptotic signaling pathway#GO:0097190;leukocyte differentiation#GO:0002521;positive regulation of cell communication#GO:0010647;positive regulation of secretion by cell#GO:1903532;autophagy#GO:0006914;complement activation#GO:0006956;export from cell#GO:0140352;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of anatomical structure morphogenesis#GO:0022603;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;biological adhesion#GO:0022610;activation of protein kinase activity#GO:0032147;protein modification process#GO:0036211;positive regulation of adaptive immune response#GO:0002821;phosphorus metabolic process#GO:0006793;cytokine production#GO:0001816;inflammatory response#GO:0006954;positive regulation of leukocyte migration#GO:0002687;phosphate-containing compound metabolic process#GO:0006796;process utilizing autophagic mechanism#GO:0061919;somatic recombination of immunoglobulin gene segments#GO:0016447;positive regulation of transferase activity#GO:0051347;regulation of biosynthetic process#GO:0009889;positive regulation of immunoglobulin mediated immune response#GO:0002891;regulation of leukocyte migration#GO:0002685;myeloid leukocyte migration#GO:0097529;positive regulation of macromolecule biosynthetic process#GO:0010557;vesicle organization#GO:0016050;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;regulation of programmed cell death#GO:0043067;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;negative regulation of biosynthetic process#GO:0009890;immunoglobulin production#GO:0002377;regulation of cell population proliferation#GO:0042127;cell-cell adhesion#GO:0098609;protein phosphorylation#GO:0006468;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of response to biotic stimulus#GO:0002831;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;regulation of inflammatory response#GO:0050727;lymphocyte differentiation#GO:0030098;positive regulation of cell migration#GO:0030335;receptor signaling pathway via STAT#GO:0097696;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;positive regulation of T cell activation#GO:0050870;positive regulation of immunoglobulin production#GO:0002639;positive regulation of cell adhesion#GO:0045785;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of DNA recombination#GO:0000018;negative regulation of gene expression#GO:0010629;cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;regulation of secretion by cell#GO:1903530;cell population proliferation#GO:0008283;lysosome localization#GO:0032418;granulocyte migration#GO:0097530;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;positive regulation of exocytosis#GO:0045921;negative regulation of cellular component movement#GO:0051271;regulation of signal transduction#GO:0009966;negative regulation of leukocyte cell-cell adhesion#GO:1903038;positive regulation of cytokine production#GO:0001819;positive regulation of immune effector process#GO:0002699;defense response to virus#GO:0051607;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;B cell activation involved in immune response#GO:0002312;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;regulation of kinase activity#GO:0043549;alpha-beta T cell differentiation#GO:0046632;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;negative regulation of T cell activation#GO:0050868;immune system development#GO:0002520;endocytosis#GO:0006897;RNA biosynthetic process#GO:0032774;negative regulation of protein metabolic process#GO:0051248;exocytic process#GO:0140029;T cell differentiation#GO:0030217;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;exocytosis#GO:0006887;leukocyte activation involved in immune response#GO:0002366;movement of cell or subcellular component#GO:0006928;positive regulation of catabolic process#GO:0009896;positive regulation of cell activation#GO:0050867;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;positive regulation of multicellular organismal process#GO:0051240;vesicle fusion#GO:0006906;macromolecule modification#GO:0043412;animal organ development#GO:0048513;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of transcription, DNA-templated#GO:0006355;regulation of hemopoiesis#GO:1903706;regulation of transport#GO:0051049;syncytium formation#GO:0006949;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of lymphocyte mediated immunity#GO:0002706;phosphorylation#GO:0016310;regulation of cell adhesion#GO:0030155;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;regulation of cell motility#GO:2000145;leukocyte mediated immunity#GO:0002443;regulation of response to stress#GO:0080134;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;regulation of cellular catabolic process#GO:0031329;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;response to external stimulus#GO:0009605;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;peptidyl-tyrosine modification#GO:0018212;vesicle budding from membrane#GO:0006900;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;establishment of localization in cell#GO:0051649;positive regulation of leukocyte chemotaxis#GO:0002690;regulation of transferase activity#GO:0051338;regulation of cellular macromolecule biosynthetic process#GO:2000112 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Interleukin#P00970 HUMAN|HGNC=18211|UniProtKB=Q9NW61 Q9NW61 PLEKHJ1 PTHR22902:SF9 SESQUIPEDALIAN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY J MEMBER 1 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;endocytosis#GO:0006897;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;early endosome#GO:0005769;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=14278|UniProtKB=Q9BYD1 Q9BYD1 MRPL13 PTHR11545:SF2 RIBOSOMAL PROTEIN L13 39S RIBOSOMAL PROTEIN L13, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular#GO:0005622 ribosomal protein#PC00202 HUMAN|HGNC=8800|UniProtKB=P01127 P01127 PDGFB PTHR11633:SF2 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR SUBUNIT B growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component movement#GO:0051272;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;inositol lipid-mediated signaling#GO:0048017;positive regulation of ERK1 and ERK2 cascade#GO:0070374;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;regulation of protein serine/threonine kinase activity#GO:0071900;protein autophosphorylation#GO:0046777;phosphatidylinositol-mediated signaling#GO:0048015;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;ERK1 and ERK2 cascade#GO:0070371;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of cell migration#GO:0030335;phosphatidylinositol 3-kinase signaling#GO:0014065;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of phosphatidylinositol 3-kinase signaling#GO:0014066;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477;regulation of transferase activity#GO:0051338 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 PDGF signaling pathway#P00047>PDGF#P01170;Angiogenesis#P00005>PDGF#P00224 HUMAN|HGNC=3805|UniProtKB=Q12950 Q12950 FOXD4 PTHR11829:SF350 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=564|UniProtKB=Q96CW1 Q96CW1 AP2M1 PTHR10529:SF236 AP COMPLEX SUBUNIT MU AP-2 COMPLEX SUBUNIT MU localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 CCKR signaling map#P06959>AP2M1#P07067 HUMAN|Gene=YQ041_HUMAN|UniProtKB=A6NJY4 A6NJY4 - PTHR28613:SF2 SI:CH211-232M10.4-RELATED HCG1800530, ISOFORM CRA_B-RELATED HUMAN|HGNC=24613|UniProtKB=Q86YC3 Q86YC3 NRROS PTHR45617:SF7 LEUCINE RICH REPEAT FAMILY PROTEIN TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC33 HUMAN|HGNC=6196|UniProtKB=Q92833 Q92833 JARID2 PTHR10694:SF44 LYSINE-SPECIFIC DEMETHYLASE PROTEIN JUMONJI demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=11467|UniProtKB=P63272 P63272 SUPT4H1 PTHR12882:SF1 SUPPRESSOR OF TY 4 TRANSCRIPTION ELONGATION FACTOR SPT4 basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;regulation of DNA-templated transcription, elongation#GO:0032784;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;DNA-templated transcription, elongation#GO:0006354;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of transcription elongation from RNA polymerase II promoter#GO:0034243;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;transcription elongation from RNA polymerase II promoter#GO:0006368;biological regulation#GO:0065007;mRNA processing#GO:0006397;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023 general transcription factor#PC00259 HUMAN|HGNC=1029|UniProtKB=P46663 P46663 BDKRB1 PTHR24228:SF28 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR B1 BRADYKININ RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=23917|UniProtKB=Q15415 Q15415 RBMY1F PTHR23147:SF65 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING MOTIF PROTEIN, Y CHROMOSOME, FAMILY 1 MEMBER A1-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=26943|UniProtKB=Q7LFL8 Q7LFL8 CXXC5 PTHR13419:SF2 ZINC FINGER-CONTAINING CXXC-TYPE ZINC FINGER PROTEIN 5 cation binding#GO:0043169;sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;organic cyclic compound binding#GO:0097159;transition metal ion binding#GO:0046914;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;metal ion binding#GO:0046872;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167 regulation of biological process#GO:0050789;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=1463|UniProtKB=Q13555 Q13555 CAMK2G PTHR24347:SF398 SERINE/THREONINE-PROTEIN KINASE CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT GAMMA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 HUMAN|HGNC=29675|UniProtKB=Q96S66 Q96S66 CLCC1 PTHR34093:SF1 CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=4040|UniProtKB=Q14332 Q14332 FZD2 PTHR11309:SF34 FRIZZLED FRIZZLED-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 HUMAN|HGNC=22644|UniProtKB=Q8NHW6 Q8NHW6 OTOS PTHR35073:SF1 OTOSPIRALIN OTOSPIRALIN multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of sound#GO:0007605;system process#GO:0003008 HUMAN|HGNC=21097|UniProtKB=Q96AQ8 Q96AQ8 MCUR1 PTHR14360:SF11 UNCHARACTERIZED MITOCHONDRIAL CALCIUM UNIPORTER REGULATOR 1 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;divalent metal ion transport#GO:0070838;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;mitochondrial calcium ion homeostasis#GO:0051560;mitochondrial transmembrane transport#GO:1990542;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;cellular chemical homeostasis#GO:0055082;mitochondrial transport#GO:0006839;mitochondrial calcium ion transmembrane transport#GO:0006851;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=30580|UniProtKB=Q76I76 Q76I76 SSH2 PTHR45864:SF3 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 2 hydrolase activity, acting on ester bonds#GO:0016788;cytoskeletal protein binding#GO:0008092;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;actin binding#GO:0003779;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 HUMAN|HGNC=29271|UniProtKB=Q9P2E3 Q9P2E3 ZNFX1 PTHR10887:SF341 DNA2/NAM7 HELICASE FAMILY NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;heterochromatin organization#GO:0070828;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;heterochromatin assembly#GO:0031507;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 HUMAN|HGNC=4762|UniProtKB=P57053 P57053 H2BS1 PTHR23428:SF300 HISTONE H2B HISTONE H2B TYPE F-S nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=6408|UniProtKB=Q9Y5Q3 Q9Y5Q3 MAFB PTHR10129:SF10 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFB cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=3760|UniProtKB=Q9NZU1 Q9NZU1 FLRT1 PTHR45712:SF15 AGAP008170-PA LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=22972|UniProtKB=P60014 P60014 KRTAP10-10 PTHR23262:SF184 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-10 HUMAN|HGNC=20202|UniProtKB=Q7Z3S7 Q7Z3S7 CACNA2D4 PTHR10166:SF59 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-4 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=13278|UniProtKB=Q9HCS5 Q9HCS5 EPB41L4A PTHR23280:SF4 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 4A HUMAN|HGNC=3029|UniProtKB=Q9Y295 Q9Y295 DRG1 PTHR43127:SF1 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=15590|UniProtKB=O94989 O94989 ARHGEF15 PTHR12845:SF7 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 15 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=23710|UniProtKB=Q9BUG6 Q9BUG6 ZSCAN5A PTHR23226:SF138 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 5A-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3522|UniProtKB=O95677 O95677 EYA4 PTHR10190:SF17 EYES ABSENT EYES ABSENT HOMOLOG 4 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of apoptotic signaling pathway#GO:2001233;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;negative regulation of apoptotic signaling pathway#GO:2001234;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;protein dephosphorylation#GO:0006470;histone modification#GO:0016570;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;response to stress#GO:0006950;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;chromatin organization#GO:0006325;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of DNA repair#GO:0045739;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;protein modification process#GO:0036211;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of DNA repair#GO:0006282;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;negative regulation of programmed cell death#GO:0043069;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cell death#GO:0008219;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of cell death#GO:0010941;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=14158|UniProtKB=Q9BSN7 Q9BSN7 TMEM204 PTHR14627:SF0 TRANSMEMBRANE PROTEIN 204 TRANSMEMBRANE PROTEIN 204 HUMAN|HGNC=30824|UniProtKB=Q6UWB4 Q6UWB4 PRSS55 PTHR24253:SF90 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 55 serine protease#PC00203 HUMAN|HGNC=22977|UniProtKB=Q9BYZ8 Q9BYZ8 REG4 PTHR22803:SF116 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED REGENERATING ISLET-DERIVED PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 HUMAN|HGNC=13553|UniProtKB=Q9Y2G3 Q9Y2G3 ATP11B PTHR24092:SF57 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IF-RELATED pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=28572|UniProtKB=Q68DX3 Q68DX3 FRMPD2 PTHR19964:SF56 MULTIPLE PDZ DOMAIN PROTEIN FERM AND PDZ DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=26055|UniProtKB=Q8N357 Q8N357 SLC35F6 PTHR13146:SF0 UNCHARACTERIZED SOLUTE CARRIER FAMILY 35 MEMBER F6 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=6010|UniProtKB=P31785 P31785 IL2RG PTHR23036:SF172 CYTOKINE RECEPTOR CYTOKINE RECEPTOR COMMON SUBUNIT GAMMA signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;growth factor receptor binding#GO:0070851;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;cytokine receptor binding#GO:0005126 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 membrane protein complex#GO:0098796;leaflet of membrane bilayer#GO:0097478;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=14137|UniProtKB=Q9H910 Q9H910 JPT2 PTHR34930:SF5 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 2 HUMAN|HGNC=11512|UniProtKB=Q9H2B2 Q9H2B2 SYT4 PTHR10024:SF114 SYNAPTOTAGMIN SYNAPTOTAGMIN-4 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cation transport#GO:0006812;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;vesicle-mediated transport#GO:0016192;response to metal ion#GO:0010038;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;membrane fusion#GO:0061025;exocytosis#GO:0006887;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;export from cell#GO:0140352 synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cell projection#GO:0042995;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Gonadotropin-releasing hormone receptor pathway#P06664>Syt IV#P06746 HUMAN|HGNC=25140|UniProtKB=O95562 O95562 SFT2D2 PTHR23137:SF1 UNCHARACTERIZED VESICLE TRANSPORT PROTEIN SFT2B HUMAN|HGNC=21039|UniProtKB=Q6P9G9 Q6P9G9 ZNF449 PTHR23226:SF4 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 449 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=38476|UniProtKB=B9A064 B9A064 IGLL5 PTHR23266:SF310 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA CONSTANT 1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=13659|UniProtKB=Q9HAZ1 Q9HAZ1 CLK4 PTHR45646:SF1 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK4 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=11241|UniProtKB=P17947 P17947 SPI1 PTHR11849:SF16 ETS TRANSCRIPTION FACTOR PU.1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 Interleukin signaling pathway#P00036>Ets#P00989 HUMAN|HGNC=23715|UniProtKB=Q96K62 Q96K62 ZBTB45 PTHR24399:SF16 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 45 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3775|UniProtKB=Q06787 Q06787 FMR1 PTHR10603:SF4 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN SYNAPTIC FUNCTIONAL REGULATOR FMR1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;protein homodimerization activity#GO:0042803;organic cyclic compound binding#GO:0097159;binding#GO:0005488;identical protein binding#GO:0042802;protein binding#GO:0005515;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;mRNA 3'-UTR binding#GO:0003730 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;cellular component biogenesis#GO:0044085;regulation of dendrite development#GO:0050773;regulation of response to DNA damage stimulus#GO:2001020;regulation of protein metabolic process#GO:0051246;heterocycle catabolic process#GO:0046700;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;central nervous system development#GO:0007417;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of translation#GO:0045727;macromolecule catabolic process#GO:0009057;regulation of multicellular organismal process#GO:0051239;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;positive regulation of macromolecule metabolic process#GO:0010604;RNA splicing#GO:0008380;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;multicellular organismal process#GO:0032501;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;plasma membrane bounded cell projection assembly#GO:0120031;translational elongation#GO:0006414;regulation of phosphorylation#GO:0042325;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;alternative mRNA splicing, via spliceosome#GO:0000380;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cell-cell signaling#GO:0007267;mRNA splicing, via spliceosome#GO:0000398;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;heterocycle metabolic process#GO:0046483;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cell morphogenesis#GO:0000902;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;positive regulation of protein metabolic process#GO:0051247;cell morphogenesis involved in neuron differentiation#GO:0048667;aromatic compound catabolic process#GO:0019439;regulation of neurogenesis#GO:0050767;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;cellular macromolecule catabolic process#GO:0044265;negative regulation of gene expression#GO:0010629;cellular localization#GO:0051641;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein modification process#GO:0031399;cell projection organization#GO:0030030;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;dendrite development#GO:0016358;microtubule-based movement#GO:0007018;regulation of synapse organization#GO:0050807;plasma membrane bounded cell projection organization#GO:0120036;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;mRNA metabolic process#GO:0016071;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;synaptic signaling#GO:0099536;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;regulation of dendritic spine development#GO:0060998;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;trans-synaptic signaling#GO:0099537;regulation of RNA stability#GO:0043487;negative regulation of protein metabolic process#GO:0051248;transport along microtubule#GO:0010970;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;neuron projection development#GO:0031175;synapse organization#GO:0050808;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;modulation of chemical synaptic transmission#GO:0050804;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;regulation of trans-synaptic signaling#GO:0099177;neuron projection morphogenesis#GO:0048812;intracellular transport#GO:0046907;regulation of synapse structure or activity#GO:0050803;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of cell morphogenesis involved in differentiation#GO:0010769;regulation of dendrite morphogenesis#GO:0048814;negative regulation of cellular metabolic process#GO:0031324;regulation of phosphate metabolic process#GO:0019220;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;macromolecule modification#GO:0043412;peptide metabolic process#GO:0006518;developmental process#GO:0032502;transport#GO:0006810;RNA processing#GO:0006396;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of cell differentiation#GO:0045595;translation#GO:0006412;positive regulation of response to stimulus#GO:0048584;axo-dendritic transport#GO:0008088;positive regulation of metabolic process#GO:0009893;cytoskeleton-dependent intracellular transport#GO:0030705;RNA catabolic process#GO:0006401;regulation of mRNA processing#GO:0050684;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;regulation of RNA metabolic process#GO:0051252;dendrite morphogenesis#GO:0048813;cell projection assembly#GO:0030031;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of RNA splicing#GO:0043484;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;microtubule-based transport#GO:0099111;regulation of cellular biosynthetic process#GO:0031326;microtubule-based process#GO:0007017;regulation of macromolecule metabolic process#GO:0060255;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell projection assembly#GO:0060491;cell junction organization#GO:0034330;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;establishment of localization in cell#GO:0051649;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 supramolecular complex#GO:0099080;synapse#GO:0045202;postsynaptic density#GO:0014069;intracellular membrane-bounded organelle#GO:0043231;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;distal axon#GO:0150034;plasma membrane region#GO:0098590;postsynapse#GO:0098794;polysome#GO:0005844;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;presynapse#GO:0098793;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;nucleus#GO:0005634;filopodium#GO:0030175;neuronal cell body#GO:0043025;cell junction#GO:0030054;cytoplasmic region#GO:0099568;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasmic ribonucleoprotein granule#GO:0036464;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell body#GO:0044297;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;growth cone#GO:0030426;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 translation factor#PC00223 HUMAN|HGNC=10332|UniProtKB=P39023 P39023 RPL3 PTHR11363:SF4 60S RIBOSOMAL PROTEIN L3-RELATED 60S RIBOSOMAL PROTEIN L3 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=5258|UniProtKB=P08238 P08238 HSP90AB1 PTHR11528:SF79 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-BETA carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of biological quality#GO:0065008;response to heat#GO:0009408;protein folding#GO:0006457;cellular response to heat#GO:0034605;biological regulation#GO:0065007;regulation of protein stability#GO:0031647;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;cellular process#GO:0009987;protein stabilization#GO:0050821 cytoplasm#GO:0005737;cell surface#GO:0009986;perinuclear region of cytoplasm#GO:0048471;intracellular#GO:0005622;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Hsp90 family chaperone#PC00028 HUMAN|HGNC=5322|UniProtKB=O43820 O43820 HYAL3 PTHR11769:SF19 HYALURONIDASE HYALURONIDASE-3 glycosidase#PC00110 HUMAN|HGNC=11951|UniProtKB=P09430 P09430 TNP1 PTHR17486:SF0 SPERMATID NUCLEAR TRANSITION PROTEIN 1 SPERMATID NUCLEAR TRANSITION PROTEIN 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 germ cell development#GO:0007281;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;nucleus organization#GO:0006997;cellular component organization#GO:0016043;spermatid differentiation#GO:0048515;cellular process#GO:0009987;multi-organism process#GO:0051704;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;organelle organization#GO:0006996;chromosome organization#GO:0051276;anatomical structure development#GO:0048856;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;chromatin organization#GO:0006325;multicellular organismal process#GO:0032501;chromatin remodeling#GO:0006338;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;protein-DNA complex#GO:0032993;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=13723|UniProtKB=P49711 P49711 CTCF PTHR24404:SF43 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR CTCF cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21645|UniProtKB=Q9Y6H1 Q9Y6H1 CHCHD2 PTHR13523:SF3 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 2-RELATED sequence-specific DNA binding#GO:0043565;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;mitochondrion organization#GO:0007005;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=33278|UniProtKB=A6NI87 A6NI87 CBY3 PTHR21533:SF17 LEUCINE-RICH PROTEIN PROTEIN CHIBBY HOMOLOG 3 HUMAN|HGNC=18945|UniProtKB=Q3LI58 Q3LI58 KRTAP21-1 PTHR31294:SF17 FAMILY NOT NAMED KERATIN-ASSOCIATED PROTEIN 21-1 HUMAN|HGNC=19982|UniProtKB=A4D1S5 A4D1S5 RAB19 PTHR24073:SF362 DRAB5-RELATED RAS-RELATED PROTEIN RAB-19 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=30910|UniProtKB=Q6PCB0 Q6PCB0 VWA1 PTHR24020:SF77 COLLAGEN ALPHA VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 1 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=34390|UniProtKB=A6NCE7 A6NCE7 MAP1LC3B2 PTHR10969:SF15 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3 BETA 2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;whole membrane#GO:0098805 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=30299|UniProtKB=Q5T3J3 Q5T3J3 LRIF1 PTHR16131:SF2 UNCHARACTERIZED LIGAND-DEPENDENT NUCLEAR RECEPTOR-INTERACTING FACTOR 1 HUMAN|HGNC=14408|UniProtKB=Q9NQF3 Q9NQF3 SERHL PTHR43329:SF72 EPOXIDE HYDROLASE SERINE HYDROLASE-LIKE PROTEIN-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|Ensembl=ENSG00000282088|UniProtKB=A0A1W2PN81 A0A1W2PN81 CHRNA7 PTHR18945:SF890 NEUROTRANSMITTER GATED ION CHANNEL CHRNA7-FAM7A FUSION PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=15983|UniProtKB=P56704 P56704 WNT3A PTHR12027:SF88 WNT RELATED PROTEIN WNT-3A receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=3168|UniProtKB=Q9HBW0 Q9HBW0 LPAR2 PTHR22750:SF38 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=1816|UniProtKB=O75871 O75871 CEACAM4 PTHR44427:SF8 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 4 HUMAN|HGNC=30869|UniProtKB=Q9UGR2 Q9UGR2 ZC3H7B PTHR14928:SF6 ROTAVIRUS 'X' ASSOCIATED NON-STRUCTURAL PROTEIN/ZINC FINGER CCCH DOMAIN CONTAINING 7 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression#GO:0010468;regulation of gene expression, epigenetic#GO:0040029;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;gene silencing by miRNA#GO:0035195;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;gene silencing by RNA#GO:0031047;cellular process#GO:0009987;primary metabolic process#GO:0044238;production of miRNAs involved in gene silencing by miRNA#GO:0035196;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;posttranscriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=1766|UniProtKB=Q9ULB5 Q9ULB5 CDH7 PTHR24027:SF91 CADHERIN-23 CADHERIN-7 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=16773|UniProtKB=Q9BYP9 Q9BYP9 KRTAP9-9 PTHR23262:SF32 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-2-RELATED HUMAN|HGNC=55|UniProtKB=O15439 O15439 ABCC4 PTHR24223:SF357 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 4 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=23143|UniProtKB=Q8NB59 Q8NB59 SYT14 PTHR46129:SF3 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN-14-RELATED HUMAN|HGNC=15919|UniProtKB=O14734 O14734 ACOT8 PTHR11066:SF34 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 8 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;lipid catabolic process#GO:0016042;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;cellular amide metabolic process#GO:0043603 esterase#PC00097 HUMAN|HGNC=10802|UniProtKB=P11686 P11686 SFTPC PTHR10800:SF4 PULMONARY SURFACTANT-ASSOCIATED PROTEIN C PULMONARY SURFACTANT-ASSOCIATED PROTEIN C surfactant#PC00212 HUMAN|HGNC=8998|UniProtKB=P78356 P78356 PIP4K2B PTHR23086:SF22 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 BETA kinase#PC00137 HUMAN|HGNC=32935|UniProtKB=Q6T423 Q6T423 SLC22A25 PTHR24064:SF217 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 25 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258 HUMAN|HGNC=3042|UniProtKB=Q9UKA8 Q9UKA8 RCAN3 PTHR10300:SF6 CALCIPRESSIN CALCIPRESSIN-3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;protein serine/threonine phosphatase activity#GO:0004722;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;regulation of signaling#GO:0023051;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 intercellular signal molecule#PC00207 HUMAN|HGNC=13213|UniProtKB=Q7Z4Y8 Q7Z4Y8 ATP5MGL PTHR12386:SF12 ATP SYNTHASE SUBUNIT ATP SYNTHASE SUBUNIT G 2, MITOCHONDRIAL-RELATED ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide biosynthetic process#GO:0009152 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 HUMAN|HGNC=21740|UniProtKB=Q6ZV73 Q6ZV73 FGD6 PTHR12673:SF12 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 6 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=571|UniProtKB=P59780 P59780 AP3S2 PTHR11753:SF10 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-3 COMPLEX SUBUNIT SIGMA-2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 HUMAN|HGNC=28170|UniProtKB=Q86T23 Q86T23 CROCCP2 PTHR23159:SF16 CENTROSOMAL PROTEIN 2 CILIARY ROOTLET COILED-COIL PROTEIN 2-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=18905|UniProtKB=Q9BYT5 Q9BYT5 KRTAP2-2 PTHR23262:SF199 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 2-2-RELATED HUMAN|HGNC=26665|UniProtKB=Q8NA57 Q8NA57 C12orf50 PTHR15725:SF1 ZN-FINGER, C-X8-C-X5-C-X3-H TYPE-CONTAINING C3H1-TYPE DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=13761|UniProtKB=Q9UBG7 Q9UBG7 RBPJL PTHR10665:SF2 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS-LIKE PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 Notch signaling pathway#P00045>Su(H)#P01101;Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Angiogenesis#P00005>CSL#P00233 HUMAN|HGNC=26740|UniProtKB=Q53RD9 Q53RD9 FBLN7 PTHR24034:SF94 EGF-LIKE DOMAIN-CONTAINING PROTEIN FIBULIN-7 extracellular matrix structural protein#PC00103 HUMAN|HGNC=25678|UniProtKB=Q9HAE3 Q9HAE3 EFCAB1 PTHR23055:SF75 CALCIUM BINDING PROTEINS EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=9117|UniProtKB=P02689 P02689 PMP2 PTHR11955:SF64 FATTY ACID BINDING PROTEIN MYELIN P2 PROTEIN HUMAN|HGNC=10576|UniProtKB=Q9Y240 Q9Y240 CLEC11A PTHR22799:SF1 TETRANECTIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 11 MEMBER A binding#GO:0005488;receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 multicellular organismal process#GO:0032501;ossification#GO:0001503 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=2577|UniProtKB=P13498 P13498 CYBA PTHR15168:SF0 CYTOCHROME B-245 LIGHT CHAIN CYTOCHROME B-245 LIGHT CHAIN cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;oxidoreductase complex#GO:1990204;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=7059|UniProtKB=P16455 P16455 MGMT PTHR46460:SF1 METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE HUMAN|HGNC=9322|UniProtKB=P53041 P53041 PPP5C PTHR45668:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 5 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 HUMAN|HGNC=29050|UniProtKB=P0C866 P0C866 LINC00869 PTHR28441:SF5 PROTEIN FAM91A1 SUBFAMILY NOT NAMED cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;vesicle localization#GO:0051648;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;vesicle targeting#GO:0006903;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=23029|UniProtKB=Q9H4B8 Q9H4B8 DPEP3 PTHR10443:SF14 MICROSOMAL DIPEPTIDASE DIPEPTIDASE 3 protease#PC00190 HUMAN|HGNC=30898|UniProtKB=Q5T686 Q5T686 AVPI1 PTHR14350:SF2 ARGININE VASOPRESSIN-INDUCED PROTEIN 1 ARGININE VASOPRESSIN-INDUCED PROTEIN 1 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 HUMAN|HGNC=1868|UniProtKB=O15182 O15182 CETN3 PTHR23050:SF325 CALCIUM BINDING PROTEIN CENTRIN-3 cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;microtubule binding#GO:0008017;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 calmodulin-related#PC00061 HUMAN|HGNC=1499|UniProtKB=P29466 P29466 CASP1 PTHR10454:SF34 CASPASE CASPASE-1 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=20881|UniProtKB=Q5T4I8 Q5T4I8 C6orf52 PTHR37457:SF1 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED TRNAU1AP DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=29650|UniProtKB=Q99640 Q99640 PKMYT1 PTHR11042:SF99 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=30227|UniProtKB=Q8TCT8 Q8TCT8 SPPL2A PTHR12174:SF34 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2A hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;lysosome#GO:0005764;intracellular#GO:0005622;cytoplasmic side of membrane#GO:0098562;leaflet of membrane bilayer#GO:0097478;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell periphery#GO:0071944;membrane#GO:0016020;lytic vacuole#GO:0000323;side of membrane#GO:0098552;whole membrane#GO:0098805;intrinsic component of endoplasmic reticulum membrane#GO:0031227;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;Golgi-associated vesicle membrane#GO:0030660;endomembrane system#GO:0012505;integral component of endoplasmic reticulum membrane#GO:0030176;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 aspartic protease#PC00053 HUMAN|HGNC=28782|UniProtKB=Q7Z6K5 Q7Z6K5 ARPIN PTHR31199:SF1 ARPIN ARPIN cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 HUMAN|HGNC=16114|UniProtKB=Q9BTX7 Q9BTX7 TTPAL PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 HUMAN|HGNC=602|UniProtKB=P06727 P06727 APOA4 PTHR18976:SF1 APOLIPOPROTEIN APOLIPOPROTEIN A-IV transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;sterol binding#GO:0032934;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;enzyme regulator activity#GO:0030234;O-acyltransferase activity#GO:0008374;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;molecular function regulator#GO:0098772;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;cholesterol binding#GO:0015485 sterol metabolic process#GO:0016125;organic hydroxy compound transport#GO:0015850;cellular component biogenesis#GO:0044085;triglyceride homeostasis#GO:0070328;sterol transport#GO:0015918;alcohol biosynthetic process#GO:0046165;cholesterol biosynthetic process#GO:0006695;positive regulation of cellular metabolic process#GO:0031325;cholesterol metabolic process#GO:0008203;lipid biosynthetic process#GO:0008610;lipid transport#GO:0006869;regulation of biological process#GO:0050789;steroid metabolic process#GO:0008202;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;anion transport#GO:0006820;secondary alcohol biosynthetic process#GO:1902653;secondary alcohol metabolic process#GO:1902652;regulation of lipid biosynthetic process#GO:0046890;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;cellular component assembly#GO:0022607;organophosphate ester transport#GO:0015748;organic anion transport#GO:0015711;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;alcohol metabolic process#GO:0006066;phospholipid transport#GO:0015914;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;cholesterol transport#GO:0030301;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;lipoprotein metabolic process#GO:0042157;regulation of lipid metabolic process#GO:0019216;small molecule biosynthetic process#GO:0044283;steroid biosynthetic process#GO:0006694;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;lipid metabolic process#GO:0006629;macromolecule localization#GO:0033036;transport#GO:0006810;protein-containing complex assembly#GO:0065003;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;lipid modification#GO:0030258;positive regulation of biosynthetic process#GO:0009891;organic substance transport#GO:0071702;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;lipid localization#GO:0010876;protein metabolic process#GO:0019538;metabolic process#GO:0008152;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;cellular lipid metabolic process#GO:0044255;sterol biosynthetic process#GO:0016126 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;high-density lipoprotein particle#GO:0034364;extracellular region#GO:0005576 apolipoprotein#PC00052 HUMAN|HGNC=5783|UniProtKB=A0A075B6P5 A0A075B6P5 IGKV2-28 PTHR23267:SF453 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-28-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=25679|UniProtKB=Q9BSB4 Q9BSB4 ATG101 PTHR13292:SF0 UNCHARACTERIZED AUTOPHAGY-RELATED PROTEIN 101 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;proteolysis#GO:0006508;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;autophagosome organization#GO:1905037;protein metabolic process#GO:0019538;autophagy#GO:0006914;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;intracellular#GO:0005622 HUMAN|HGNC=3337|UniProtKB=Q9UHX3 Q9UHX3 ADGRE2 PTHR12011:SF328 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=5126|UniProtKB=P09017 P09017 HOXC4 PTHR45771:SF9 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-C4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10322|UniProtKB=Q16540 Q16540 MRPL23 PTHR12059:SF5 RIBOSOMAL PROTEIN L23-RELATED 39S RIBOSOMAL PROTEIN L23, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=7599|UniProtKB=Q12965 Q12965 MYO1E PTHR13140:SF341 MYOSIN UNCONVENTIONAL MYOSIN-IE pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 microvillus#GO:0005902;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=4375|UniProtKB=Q99445 Q99445 GML PTHR15049:SF2 GLYCOSYL-PHOSPHATIDYLINOSITOL-ANCHORED MOLECULE-LIKE PROTEIN-RELATED GLYCOSYL-PHOSPHATIDYLINOSITOL-ANCHORED MOLECULE-LIKE PROTEIN HUMAN|HGNC=20069|UniProtKB=Q9NVE5 Q9NVE5 USP40 PTHR24006:SF842 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 40 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=10528|UniProtKB=Q9NSI8 Q9NSI8 SAMSN1 PTHR12301:SF4 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM DOMAIN-CONTAINING PROTEIN SAMSN-1 HUMAN|HGNC=679|UniProtKB=P52566 P52566 ARHGDIB PTHR10980:SF15 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rho GTPase binding#GO:0017048;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;Rac GTPase binding#GO:0048365;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 G-protein modulator#PC00022 HUMAN|HGNC=13532|UniProtKB=O43711 O43711 TLX3 PTHR45921:SF1 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=51617|UniProtKB=P0DN25 P0DN25 C1GALT1C1L PTHR23033:SF38 BETA1,3-GALACTOSYLTRANSFERASE C1GALT1-SPECIFIC CHAPERONE 1-LIKE PROTEIN transferase activity, transferring hexosyl groups#GO:0016758;galactosyltransferase activity#GO:0008378;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=11378|UniProtKB=Q9UHE8 Q9UHE8 STEAP1 PTHR14239:SF3 DUDULIN-RELATED METALLOREDUCTASE STEAP1-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;iron ion transmembrane transport#GO:0034755;localization#GO:0051179;establishment of localization#GO:0051234;oxidation-reduction process#GO:0055114;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;metabolic process#GO:0008152 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=14889|UniProtKB=Q9UBS4 Q9UBS4 DNAJB11 PTHR44298:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 chaperone#PC00072 HUMAN|HGNC=14552|UniProtKB=Q14164 Q14164 IKBKE PTHR22969:SF10 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT EPSILON transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>IKKepsilon#P01372;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871 HUMAN|HGNC=33892|UniProtKB=A6NJZ7 A6NJZ7 RIMBP3C PTHR14234:SF21 RIM BINDING PROTEIN-RELATED RIMS-BINDING PROTEIN 3A-RELATED germ cell development#GO:0007281;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;spermatid differentiation#GO:0048515;cellular process#GO:0009987;multi-organism process#GO:0051704;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;synaptic signaling#GO:0099536;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;neuromuscular synaptic transmission#GO:0007274;multi-organism reproductive process#GO:0044703;cell-cell signaling#GO:0007267;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7150|UniProtKB=O95822 O95822 MLYCD PTHR28641:SF1 FAMILY NOT NAMED MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL HUMAN|HGNC=3255|UniProtKB=Q9NZJ5 Q9NZJ5 EIF2AK3 PTHR11042:SF166 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2AK3#P06813 HUMAN|HGNC=12036|UniProtKB=Q9Y4K3 Q9Y4K3 TRAF6 PTHR10131:SF131 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 6 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 regulation of MAPK cascade#GO:0043408;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;positive regulation of protein modification process#GO:0031401;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;stress-activated MAPK cascade#GO:0051403;cellular protein metabolic process#GO:0044267;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of DNA-binding transcription factor activity#GO:0051091;positive regulation of protein metabolic process#GO:0051247;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;transcription, DNA-templated#GO:0006351;regulation of JNK cascade#GO:0046328;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;JNK cascade#GO:0007254;positive regulation of signaling#GO:0023056;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;tumor necrosis factor-mediated signaling pathway#GO:0033209;RNA biosynthetic process#GO:0032774;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;response to interleukin-1#GO:0070555;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of stress-activated MAPK cascade#GO:0032874;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of stress-activated protein kinase signaling cascade#GO:0070302;cellular macromolecule biosynthetic process#GO:0034645;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of stress-activated MAPK cascade#GO:0032872;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;protein K63-linked ubiquitination#GO:0070534 membrane protein complex#GO:0098796;receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>TRAF6#P07111;p38 MAPK pathway#P05918>TRAF6#P06038;Toll receptor signaling pathway#P00054>TRAF6#P01371 HUMAN|HGNC=37619|UniProtKB=A6NIE6 A6NIE6 RRN3P2 PTHR12790:SF0 TRANSCRIPTION INITIATION FACTOR IA RRN3 RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 HUMAN|HGNC=30305|UniProtKB=Q13156 Q13156 RPA4 PTHR13989:SF43 REPLICATION PROTEIN A-RELATED REPLICATION PROTEIN A 30 KDA SUBUNIT-RELATED DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 pre-replicative complex#GO:0036387;intracellular membrane-bounded organelle#GO:0043231;epsilon DNA polymerase complex#GO:0008622;replisome#GO:0030894;MCM complex#GO:0042555;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;chromosomal region#GO:0098687;replication fork#GO:0005657;membrane-enclosed lumen#GO:0031974;origin recognition complex#GO:0000808;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;DNA replication preinitiation complex#GO:0031261;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;CMG complex#GO:0071162;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;chromosome, telomeric region#GO:0000781;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 DNA replication#P00017>RPA#P00537 HUMAN|HGNC=28095|UniProtKB=Q6ZP65 Q6ZP65 BICDL1 PTHR32123:SF12 BICD FAMILY-LIKE CARGO ADAPTER BICD FAMILY-LIKE CARGO ADAPTER 1 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=19181|UniProtKB=Q15058 Q15058 KIF14 PTHR24115:SF546 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF14 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=26937|UniProtKB=O43715 O43715 TRIAP1 PTHR46403:SF1 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 HUMAN|HGNC=13848|UniProtKB=Q9NR11 Q9NR11 ZNF302 PTHR24377:SF395 IP01015P-RELATED ZINC FINGER PROTEIN 181-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19658|UniProtKB=Q7RTS5 Q7RTS5 OTOP3 PTHR21522:SF36 PROTON CHANNEL OTOP PROTON CHANNEL OTOP3 transporter#PC00227 HUMAN|HGNC=4573|UniProtKB=P42263 P42263 GRIA3 PTHR18966:SF151 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 3 amino acid binding#GO:0016597;cation channel activity#GO:0005261;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;glutamate binding#GO:0016595;ligand-gated channel activity#GO:0022834 membrane protein complex#GO:0098796;synapse#GO:0045202;somatodendritic compartment#GO:0036477;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;cell periphery#GO:0071944;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;postsynapse#GO:0098794;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>Glu3#P01016;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019 HUMAN|HGNC=11123|UniProtKB=P52788 P52788 SMS PTHR46315:SF2 SPERMINE SYNTHASE SPERMINE SYNTHASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=23111|UniProtKB=Q6V1P9 Q6V1P9 DCHS2 PTHR24026:SF99 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN-23 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|Gene=ERVFC1|UniProtKB=P60507 P60507 ERVFC1 PTHR10424:SF63 VIRAL ENVELOPE PROTEIN ENDOGENOUS RETROVIRUS GROUP FC1 ENV POLYPROTEIN viral or transposable element protein#PC00237 HUMAN|HGNC=27258|UniProtKB=Q86VR2 Q86VR2 RETREG3 PTHR28659:SF1 FAMILY NOT NAMED RETICULOPHAGY REGULATOR 3 HUMAN|HGNC=13841|UniProtKB=Q86SQ4 Q86SQ4 ADGRG6 PTHR12011:SF290 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G6 signaling receptor activity#GO:0038023;extracellular matrix binding#GO:0050840;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;heart development#GO:0007507;signal transduction#GO:0007165;neurogenesis#GO:0022008;second-messenger-mediated signaling#GO:0019932;animal organ development#GO:0048513;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;regulation of signaling#GO:0023051;gliogenesis#GO:0042063;peripheral nervous system development#GO:0007422;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;glial cell differentiation#GO:0010001;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;heart morphogenesis#GO:0003007;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935;myelination#GO:0042552 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=399|UniProtKB=P02768 P02768 ALB PTHR11385:SF15 SERUM ALBUMIN-RELATED ALBUMIN localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 transfer/carrier protein#PC00219 HUMAN|HGNC=24190|UniProtKB=Q7Z7J9 Q7Z7J9 CAMK2N1 PTHR31007:SF3 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 1 protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;protein phosphorylation#GO:0006468;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 kinase inhibitor#PC00139 HUMAN|HGNC=44121|UniProtKB=P0C264 P0C264 SBK3 PTHR24363:SF6 SERINE/THREONINE PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=4766|UniProtKB=P68431 P68431 H3C12 PTHR11426:SF242 HISTONE H3 HISTONE H3.1 histone#PC00118 DNA replication#P00017>Histones#P00527 HUMAN|HGNC=5704|UniProtKB=P0DTE2 P0DTE2 IGHV8-51-1 PTHR23266:SF204 IMMUNOGLOBULIN HEAVY CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=100|UniProtKB=P78348 P78348 ASIC1 PTHR11690:SF170 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=16460|UniProtKB=O94887 O94887 FARP2 PTHR45858:SF4 FERM DOMAIN CONTAINING PROTEIN FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 2 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Rac GTPase binding#GO:0048365;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 HUMAN|HGNC=21143|UniProtKB=O43167 O43167 ZBTB24 PTHR24404:SF45 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 24 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=19840|UniProtKB=Q8NDC0 Q8NDC0 MAPK1IP1L PTHR35973:SF1 MAPK-INTERACTING AND SPINDLE-STABILIZING PROTEIN-LIKE MAPK-INTERACTING AND SPINDLE-STABILIZING PROTEIN-LIKE HUMAN|HGNC=7585|UniProtKB=P12829 P12829 MYL4 PTHR23048:SF1 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 4 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=22404|UniProtKB=Q8NHV1 Q8NHV1 GIMAP7 PTHR10903:SF163 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 7 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 small GTPase#PC00208 HUMAN|HGNC=11506|UniProtKB=P08247 P08247 SYP PTHR10306:SF10 SYNAPTOPHYSIN SYNAPTOPHYSIN syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;syntaxin-1 binding#GO:0017075 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptophysin#P05777 HUMAN|HGNC=15985|UniProtKB=Q4LDE5 Q4LDE5 SVEP1 PTHR19325:SF43 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=15347|UniProtKB=Q8NGC9 Q8NGC9 OR11H4 PTHR24247:SF99 5-HYDROXYTRYPTAMINE RECEPTOR OLFACTORY RECEPTOR 11H4 cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=29593|UniProtKB=Q7Z713 Q7Z713 ANKRD37 PTHR24201:SF0 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 37 HUMAN|HGNC=17450|UniProtKB=Q9HB55 Q9HB55 CYP3A43 PTHR24302:SF6 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A43 steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;oxidative demethylation#GO:0070989;oxidation-reduction process#GO:0055114;demethylation#GO:0070988;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177 HUMAN|HGNC=5259|UniProtKB=Q58FF7 Q58FF7 HSP90AB3P PTHR11528:SF81 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-BETA-3-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of biological quality#GO:0065008;response to heat#GO:0009408;protein folding#GO:0006457;cellular response to heat#GO:0034605;biological regulation#GO:0065007;regulation of protein stability#GO:0031647;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;cellular process#GO:0009987;protein stabilization#GO:0050821 cytoplasm#GO:0005737;cell surface#GO:0009986;perinuclear region of cytoplasm#GO:0048471;intracellular#GO:0005622;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Hsp90 family chaperone#PC00028 HUMAN|HGNC=24114|UniProtKB=Q9NWT8 Q9NWT8 AURKAIP1 PTHR32035:SF3 AURORA KINASE A-INTERACTING PROTEIN AURORA KINASE A-INTERACTING PROTEIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=19260|UniProtKB=Q9NPC1 Q9NPC1 LTB4R2 PTHR24230:SF8 G-PROTEIN COUPLED RECEPTOR LEUKOTRIENE B4 RECEPTOR 2 signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;organic acid binding#GO:0043177;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to stress#GO:0006950;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;defense response#GO:0006952;cellular process#GO:0009987;signaling#GO:0023052;inflammatory response#GO:0006954 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=11934|UniProtKB=P23510 P23510 TNFSF4 PTHR17534:SF4 OX40 LIGAND TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 4 HUMAN|HGNC=9800|UniProtKB=Q9UNT1 Q9UNT1 RABL2B PTHR24073:SF263 DRAB5-RELATED RAB-LIKE PROTEIN 2A-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=2323|UniProtKB=P31327 P31327 CPS1 PTHR11405:SF38 CARBAMOYLTRANSFERASE FAMILY MEMBER CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL oxoacid metabolic process#GO:0043436;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid metabolic process#GO:0006520;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925;Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845 HUMAN|HGNC=16761|UniProtKB=Q86WZ0 Q86WZ0 HEATR4 PTHR12697:SF20 PBS LYASE HEAT-LIKE PROTEIN HEAT REPEAT-CONTAINING PROTEIN 4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 HUMAN|HGNC=32315|UniProtKB=Q5JR98 Q5JR98 TCTEX1D4 PTHR21255:SF55 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN TCTEX1 DOMAIN-CONTAINING PROTEIN 4 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=14153|UniProtKB=A2IDD5 A2IDD5 CCDC78 PTHR22106:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 78 COILED-COIL DOMAIN-CONTAINING PROTEIN 78 HUMAN|HGNC=21174|UniProtKB=Q5TFG8 Q5TFG8 ZC2HC1B PTHR13555:SF51 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1B C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=19573|UniProtKB=Q8NGZ9 Q8NGZ9 OR2T10 PTHR26453:SF101 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T10 transmembrane signal receptor#PC00197 HUMAN|HGNC=947|UniProtKB=Q9UQB8 Q9UQB8 BAIAP2 PTHR14206:SF3 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;actin cytoskeleton reorganization#GO:0031532;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=24618|UniProtKB=Q8WYP5 Q8WYP5 AHCTF1 PTHR21583:SF8 ELYS PROTEIN PROTEIN ELYS scaffold/adaptor protein#PC00226 HUMAN|HGNC=16208|UniProtKB=Q8WUT4 Q8WUT4 LRRN4 PTHR24366:SF13 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT NEURONAL PROTEIN 4 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=7|UniProtKB=P01023 P01023 A2M PTHR11412:SF165 MACROGLOBULIN / COMPLEMENT ALPHA-2-MACROGLOBULIN protease inhibitor#PC00191 Blood coagulation#P00011>alpha2-macroglobulin#P00427 HUMAN|HGNC=27446|UniProtKB=Q494R4 Q494R4 CCDC153 PTHR28656:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 153 COILED-COIL DOMAIN-CONTAINING PROTEIN 153 HUMAN|HGNC=1348|UniProtKB=Q5K651 Q5K651 SAMD9 PTHR16155:SF17 DED DOMAIN-CONTAINING PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=30883|UniProtKB=Q8IUX1 Q8IUX1 TMEM126B PTHR16296:SF3 UNCHARACTERIZED HYPOTHALAMUS PROTEIN HT007 COMPLEX I ASSEMBLY FACTOR TMEM126B, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=8943|UniProtKB=Q99574 Q99574 SERPINI1 PTHR11461:SF50 SERINE PROTEASE INHIBITOR, SERPIN NEUROSERPIN serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=20419|UniProtKB=Q15048 Q15048 LRRC14 PTHR14224:SF9 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=3182|UniProtKB=P78364 P78364 PHC1 PTHR12247:SF20 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 1 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=9521|UniProtKB=Q00888 Q00888 PSG4 PTHR44427:SF17 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED HUMAN|HGNC=34436|UniProtKB=Q6ZST4 Q6ZST4 LCNL1 PTHR11430:SF77 LIPOCALIN LIPOCALIN-LIKE 1 PROTEIN transfer/carrier protein#PC00219 HUMAN|HGNC=7611|UniProtKB=P15172 P15172 MYOD1 PTHR11534:SF2 MYOGENIC FACTOR MYOBLAST DETERMINATION PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;nucleobase-containing compound metabolic process#GO:0006139;muscle structure development#GO:0061061;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of cell differentiation#GO:0045597;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of developmental process#GO:0051094;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=28862|UniProtKB=Q6KC79 Q6KC79 NIPBL PTHR21704:SF18 NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED NIPPED-B-LIKE PROTEIN chromatin binding#GO:0003682;binding#GO:0005488 positive regulation of gene expression#GO:0010628;nuclear division#GO:0000280;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of mitotic sister chromatid segregation#GO:0033047;positive regulation of mitotic cell cycle#GO:0045931;regulation of protein localization#GO:0032880;sister chromatid segregation#GO:0000819;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;double-strand break repair via homologous recombination#GO:0000724;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;chromosome condensation#GO:0030261;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;sister chromatid cohesion#GO:0007062;organic cyclic compound metabolic process#GO:1901360;positive regulation of cell cycle process#GO:0090068;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;protein localization to organelle#GO:0033365;regulation of macromolecule biosynthetic process#GO:0010556;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of nuclear division#GO:0051783;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;mitotic chromosome condensation#GO:0007076;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of mitotic cell cycle#GO:0007346;transcription by RNA polymerase II#GO:0006366;DNA repair#GO:0006281;regulation of mitotic nuclear division#GO:0007088;cellular localization#GO:0051641;regulation of chromosome segregation#GO:0051983;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;establishment of protein localization#GO:0045184;transcription, DNA-templated#GO:0006351;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;nuclear chromosome segregation#GO:0098813;positive regulation of transcription, DNA-templated#GO:0045893;mitotic sister chromatid cohesion#GO:0007064;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;RNA biosynthetic process#GO:0032774;regulation of cellular localization#GO:0060341;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;DNA packaging#GO:0006323;response to stress#GO:0006950;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule localization#GO:0033036;positive regulation of organelle organization#GO:0010638;regulation of transcription by RNA polymerase II#GO:0006357;mitotic cell cycle process#GO:1903047;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;positive regulation of mitotic nuclear division#GO:0045840;establishment of protein localization to organelle#GO:0072594;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;organelle fission#GO:0048285;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=7648|UniProtKB=Q8NFP9 Q8NFP9 NBEA PTHR13743:SF62 BEIGE/BEACH-RELATED NEUROBEACHIN enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 localization#GO:0051179;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=37250|UniProtKB=B6A8C7 B6A8C7 TARM1 PTHR11738:SF157 MHC CLASS I NK CELL RECEPTOR T-CELL-INTERACTING, ACTIVATING RECEPTOR ON MYELOID CELLS PROTEIN 1 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=25579|UniProtKB=Q9NVE4 Q9NVE4 CCDC87 PTHR16078:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 87 COILED-COIL DOMAIN-CONTAINING PROTEIN 87 HUMAN|HGNC=20985|UniProtKB=Q99990 Q99990 VGLL1 PTHR15950:SF20 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=33908|UniProtKB=Q6NUM6 Q6NUM6 TYW1B PTHR13930:SF0 S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED lyase#PC00144 HUMAN|HGNC=3226|UniProtKB=P98172 P98172 EFNB1 PTHR11304:SF17 EPHRIN EPHRIN-B1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 Angiogenesis#P00005>Eph#P00239 HUMAN|HGNC=28034|UniProtKB=Q5EBL8 Q5EBL8 PDZD11 PTHR14063:SF1 PROTEIN LIN-7 HOMOLOG PDZ DOMAIN-CONTAINING PROTEIN 11 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;establishment or maintenance of bipolar cell polarity#GO:0061245;export from cell#GO:0140352 synapse#GO:0045202;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;cell junction#GO:0030054;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070 HUMAN|HGNC=1857|UniProtKB=P49454 P49454 CENPF PTHR18874:SF10 CMF/LEK/CENP CELL DIVISION-RELATED CENTROMERE PROTEIN F HUMAN|HGNC=2184|UniProtKB=P38432 P38432 COIL PTHR15197:SF0 COILIN P80 COILIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=9391|UniProtKB=P13861 P13861 PRKAR2A PTHR11635:SF153 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE II-ALPHA REGULATORY SUBUNIT carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;molecular function regulator#GO:0098772;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 protein-containing complex#GO:0032991;intracellular#GO:0005622 kinase modulator#PC00140 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Hedgehog signaling pathway#P00025>PKA#P00682;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Endothelin signaling pathway#P00019>PKA#P00570 HUMAN|HGNC=2296|UniProtKB=P15085 P15085 CPA1 PTHR11705:SF94 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A1 hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=3489|UniProtKB=P15036 P15036 ETS2 PTHR11849:SF188 ETS PROTEIN C-ETS-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=30781|UniProtKB=Q86TJ2 Q86TJ2 TADA2B PTHR12374:SF63 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-BETA transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;binding#GO:0005488 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;positive regulation of protein modification process#GO:0031401;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of chromatin organization#GO:1902275;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of histone modification#GO:0031056;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of cellular protein metabolic process#GO:0032270;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=11159|UniProtKB=P62316 P62316 SNRPD2 PTHR12777:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974 RNA processing factor#PC00147 HUMAN|HGNC=2216|UniProtKB=P25067 P25067 COL8A2 PTHR24023:SF855 COLLAGEN ALPHA COLLAGEN ALPHA-2(VIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=33749|UniProtKB=Q52MB2 Q52MB2 CCDC184 PTHR31554:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 184 COILED-COIL DOMAIN-CONTAINING PROTEIN 184 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=34361|UniProtKB=A6NNP5 A6NNP5 CCDC169 PTHR28671:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 169 COILED-COIL DOMAIN-CONTAINING PROTEIN 169 HUMAN|HGNC=21060|UniProtKB=Q8TAA5 Q8TAA5 GRPEL2 PTHR21237:SF10 GRPE PROTEIN GRPE PROTEIN HOMOLOG 2, MITOCHONDRIAL nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068 HUMAN|HGNC=37157|UniProtKB=P0CJ70 P0CJ70 MTRNR2L3 PTHR33895:SF7 HUMANIN-LIKE 4 HUMANIN-LIKE 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=25210|UniProtKB=Q8WWB5 Q8WWB5 PIH1D2 PTHR22997:SF6 UNCHARACTERIZED PIH1 DOMAIN-CONTAINING PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=20884|UniProtKB=Q9ULL1 Q9ULL1 PLEKHG1 PTHR45924:SF1 FI17866P1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 1 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 HUMAN|HGNC=9408|UniProtKB=O94806 O94806 PRKD3 PTHR22968:SF26 PROTEIN KINASE C, MU SERINE/THREONINE-PROTEIN KINASE D3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;EGF receptor signaling pathway#P00018>PKC#P00565 HUMAN|HGNC=12143|UniProtKB=A0A0B4J249 A0A0B4J249 TRAV5 PTHR19433:SF76 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 5 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=5996|UniProtKB=Q9NZN1 Q9NZN1 IL1RAPL1 PTHR11890:SF22 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN-LIKE 1 vesicle fusion#GO:0006906;negative regulation of biological process#GO:0048519;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;negative regulation of cellular process#GO:0048523;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;negative regulation of transport#GO:0051051;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;export from cell#GO:0140352 transmembrane signal receptor#PC00197 HUMAN|HGNC=13445|UniProtKB=Q6PXP3 Q6PXP3 SLC2A7 PTHR23503:SF30 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 7 HUMAN|HGNC=13880|UniProtKB=B0I1T2 B0I1T2 MYO1G PTHR13140:SF381 MYOSIN UNCONVENTIONAL MYOSIN-IG pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 microvillus#GO:0005902;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=29319|UniProtKB=A0MZ66 A0MZ66 SHTN1 PTHR46606:SF3 SHOOTIN-1 SHOOTIN-1 HUMAN|HGNC=27801|UniProtKB=Q5FWF6 Q5FWF6 ZNF789 PTHR24377:SF196 IP01015P-RELATED ZINC FINGER PROTEIN 789 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=13054|UniProtKB=Q14202 Q14202 ZMYM3 PTHR45736:SF3 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 3 zinc finger transcription factor#PC00244 HUMAN|HGNC=3169|UniProtKB=O95136 O95136 S1PR2 PTHR22750:SF17 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=31793|UniProtKB=Q8TCE6 Q8TCE6 DENND10 PTHR28544:SF1 PROTEIN FAM45A-RELATED DENN DOMAIN-CONTAINING PROTEIN 10-RELATED HUMAN|HGNC=1393|UniProtKB=O60840 O60840 CACNA1F PTHR45628:SF2 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1F calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812;calcium ion transport#GO:0006816 voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096 HUMAN|HGNC=21|UniProtKB=Q6ZMQ8 Q6ZMQ8 AATK PTHR24417:SF0 SERINE/THREONINE-PROTEIN KINASE LMTK1 SERINE/THREONINE-PROTEIN KINASE LMTK1 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 head development#GO:0060322;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;developmental process#GO:0032502;brain development#GO:0007420;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;central nervous system development#GO:0007417;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;peptidyl-tyrosine modification#GO:0018212;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=4208|UniProtKB=P23434 P23434 GCSH PTHR11715:SF28 GLYCINE CLEAVAGE SYSTEM H PROTEIN GLYCINE CLEAVAGE SYSTEM H PROTEIN, MITOCHONDRIAL HUMAN|HGNC=17648|UniProtKB=Q9HBU9 Q9HBU9 POPDC2 PTHR12101:SF15 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;muscle organ development#GO:0007517;heart development#GO:0007507;muscle cell differentiation#GO:0042692;circulatory system development#GO:0072359;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular process#GO:0009987;tissue development#GO:0009888;muscle tissue development#GO:0060537;muscle structure development#GO:0061061;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;system development#GO:0048731;striated muscle tissue development#GO:0014706;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;skeletal muscle tissue development#GO:0007519 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;sarcolemma#GO:0042383;plasma membrane#GO:0005886 HUMAN|HGNC=8873|UniProtKB=O60825 O60825 PFKFB2 PTHR10606:SF48 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578 carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 carbohydrate phosphatase#PC00066 HUMAN|HGNC=9707|UniProtKB=Q92692 Q92692 NECTIN2 PTHR47387:SF1 NECTIN-2 NECTIN-2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;male gamete generation#GO:0048232;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;activation of immune response#GO:0002253;membrane organization#GO:0061024;positive regulation of signal transduction#GO:0009967;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;endomembrane system organization#GO:0010256;lymphocyte mediated immunity#GO:0002449;positive regulation of leukocyte activation#GO:0002696;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;spermatogenesis#GO:0007283;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;positive regulation of immune effector process#GO:0002699;regulation of adaptive immune response#GO:0002819;positive regulation of signaling#GO:0023056;defense response#GO:0006952;multi-organism reproductive process#GO:0044703;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;leukocyte activation#GO:0045321;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;gamete generation#GO:0007276;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;regulation of immune response#GO:0050776;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;positive regulation of lymphocyte mediated immunity#GO:0002708;positive regulation of cellular process#GO:0048522;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;cell activation#GO:0001775;developmental process involved in reproduction#GO:0003006;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;reproduction#GO:0000003;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;regulation of defense response#GO:0031347;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of defense response#GO:0031349;signal transduction#GO:0007165;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;spermatid differentiation#GO:0048515;positive regulation of adaptive immune response#GO:0002821;cell differentiation#GO:0030154;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;positive regulation of immunoglobulin mediated immune response#GO:0002891;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of lymphocyte mediated immunity#GO:0002706;vesicle organization#GO:0016050;regulation of immune system process#GO:0002682;immune effector process#GO:0002252;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular component assembly involved in morphogenesis#GO:0010927;regulation of response to external stimulus#GO:0032101;multicellular organism reproduction#GO:0032504;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;T cell mediated immunity#GO:0002456;cellular process#GO:0009987;multi-organism process#GO:0051704;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;organelle assembly#GO:0070925;cell development#GO:0048468;regulation of response to biotic stimulus#GO:0002831;regulation of innate immune response#GO:0045088;localization#GO:0051179;response to stimulus#GO:0050896;regulation of immune effector process#GO:0002697;response to external stimulus#GO:0009605;spermatid development#GO:0007286;immune system process#GO:0002376;multi-organism cellular process#GO:0044764;regulation of leukocyte activation#GO:0002694;membrane fusion#GO:0061025;response to other organism#GO:0051707;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of response to biotic stimulus#GO:0002833;T cell receptor signaling pathway#GO:0050852 extracellular region#GO:0005576;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intrinsic component of membrane#GO:0031224;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;membrane-bounded organelle#GO:0043227;apical junction complex#GO:0043296;plasma membrane#GO:0005886 HUMAN|HGNC=26384|UniProtKB=Q6WRI0 Q6WRI0 IGSF10 PTHR45842:SF2 SYNAPTIC ADHESION-LIKE MOLECULE SALM IMMUNOGLOBULIN SUPERFAMILY MEMBER 10 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=13938|UniProtKB=Q5SSQ6 Q5SSQ6 SAPCD1 PTHR14907:SF4 FI14130P SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=22194|UniProtKB=Q6PID8 Q6PID8 KLHDC10 PTHR46428:SF1 KELCH DOMAIN-CONTAINING PROTEIN 10 KELCH DOMAIN-CONTAINING PROTEIN 10 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;regulation of stress-activated MAPK cascade#GO:0032872;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 HUMAN|HGNC=33703|UniProtKB=A0PJX0 A0PJX0 CIB4 PTHR45791:SF4 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 4 HUMAN|HGNC=10742|UniProtKB=P04279 P04279 SEMG1 PTHR10547:SF4 SEMENOGELIN/SEMINAL VESICLE SECRETORY PROTEIN SEMENOGELIN-1 sperm capacitation#GO:0048240;germ cell development#GO:0007281;cellular developmental process#GO:0048869;male gamete generation#GO:0048232;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;spermatid differentiation#GO:0048515;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;anatomical structure development#GO:0048856;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 HUMAN|HGNC=15678|UniProtKB=P0DPB3 P0DPB3 SCHIP1 PTHR13103:SF5 SCHWANNOMIN INTERACTING PROTEIN 1 SCHWANNOMIN-INTERACTING PROTEIN 1 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;hippo signaling#GO:0035329;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;signaling#GO:0023052;positive regulation of biological process#GO:0048518 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=26160|UniProtKB=Q8IYQ7 Q8IYQ7 THNSL1 PTHR43515:SF1 THREONINE SYNTHASE-LIKE 1 THREONINE SYNTHASE-LIKE 1 Threonine biosynthesis#P02781>Threonine synthase#P03190 HUMAN|HGNC=26741|UniProtKB=Q5XG92 Q5XG92 CES4A PTHR11559:SF254 CARBOXYLESTERASE CARBOXYLESTERASE 4A hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 esterase#PC00097 HUMAN|HGNC=39602|UniProtKB=B9A014 B9A014 FAM243A PTHR35969:SF1 PROTEIN FAM243A-RELATED PROTEIN FAM243A-RELATED HUMAN|HGNC=3212|UniProtKB=O43324 O43324 EEF1E1 PTHR44490:SF1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 translation elongation factor#PC00222 HUMAN|HGNC=25139|UniProtKB=Q86YJ5 Q86YJ5 MARCHF9 PTHR46053:SF4 E3 UBIQUITIN-PROTEIN LIGASE MARCH4-LIKE E3 UBIQUITIN-PROTEIN LIGASE MARCHF9 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=27035|UniProtKB=Q14CS0 Q14CS0 UBXN2B PTHR23333:SF40 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 2B protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;membrane organization#GO:0061024;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;Golgi organization#GO:0007030;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;nuclear envelope organization#GO:0006998;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;autophagy#GO:0006914 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=7160|UniProtKB=P50281 P50281 MMP14 PTHR10201:SF24 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-14 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component organization#GO:0016043;skeletal system development#GO:0001501;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;extracellular structure organization#GO:0043062;nitrogen compound metabolic process#GO:0006807;anatomical structure development#GO:0048856;proteolysis#GO:0006508;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Gonadotropin-releasing hormone receptor pathway#P06664>MT1-MMP#P06716;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=2860|UniProtKB=Q9UBM7 Q9UBM7 DHCR7 PTHR21257:SF38 DELTA(14)-STEROL REDUCTASE 7-DEHYDROCHOLESTEROL REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;hormone biosynthetic process#GO:0042446;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;regulation of hormone levels#GO:0010817;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;phytosteroid metabolic process#GO:0016128;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;steroid biosynthetic process#GO:0006694;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 reductase#PC00198 HUMAN|HGNC=19019|UniProtKB=Q7Z4K8 Q7Z4K8 TRIM46 PTHR24099:SF20 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 46 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=5195|UniProtKB=Q9Y278 Q9Y278 HS3ST2 PTHR10605:SF10 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 HUMAN|HGNC=13943|UniProtKB=Q99946 Q99946 PRRT1 PTHR14948:SF21 NG5 PROLINE-RICH TRANSMEMBRANE PROTEIN 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=20152|UniProtKB=Q9C0A1 Q9C0A1 ZFHX2 PTHR45891:SF1 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;regulation of neuron differentiation#GO:0045664;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1613|UniProtKB=O14618 O14618 CCS PTHR10003:SF86 SUPEROXIDE DISMUTASE CU-ZN -RELATED COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to toxic substance#GO:0009636;cellular response to stress#GO:0033554;metabolic process#GO:0008152 oxidoreductase#PC00176 HUMAN|HGNC=12525|UniProtKB=O60701 O60701 UGDH PTHR11374:SF3 UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE UDP-GLUCOSE 6-DEHYDROGENASE dehydrogenase#PC00092 HUMAN|HGNC=11443|UniProtKB=Q9UNK0 Q9UNK0 STX8 PTHR19957:SF322 SYNTAXIN SYNTAXIN-8 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 HUMAN|HGNC=23385|UniProtKB=Q5JVG2 Q5JVG2 ZNF484 PTHR24376:SF48 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 484 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20853|UniProtKB=Q96MT1 Q96MT1 RNF145 PTHR22763:SF167 RING ZINC FINGER PROTEIN RING FINGER PROTEIN 145 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=25945|UniProtKB=Q9NXU5 Q9NXU5 ARL15 PTHR46693:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 HUMAN|HGNC=8010|UniProtKB=Q9Y4C0 Q9Y4C0 NRXN3 PTHR15036:SF57 PIKACHURIN-LIKE PROTEIN NEUREXIN-3 HUMAN|HGNC=15230|UniProtKB=Q8NGI2 Q8NGI2 OR52N4 PTHR26450:SF194 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N4 transmembrane signal receptor#PC00197 HUMAN|HGNC=16447|UniProtKB=Q96SE7 Q96SE7 ZNF347 PTHR24377:SF625 IP01015P-RELATED ZINC FINGER PROTEIN 347 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12886|UniProtKB=Q9H2Y7 Q9H2Y7 ZNF106 PTHR14435:SF2 ZINC FINGER PROTEIN 106 ZINC FINGER PROTEIN 106 HUMAN|HGNC=10306|UniProtKB=P61313 P61313 RPL15 PTHR11847:SF4 RIBOSOMAL PROTEIN L15 60S RIBOSOMAL PROTEIN L15 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=4460|UniProtKB=P51674 P51674 GPM6A PTHR11683:SF4 MYELIN PROTEOLIPID NEURONAL MEMBRANE GLYCOPROTEIN M6-A cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;somatodendritic compartment#GO:0036477;filopodium#GO:0030175;neuronal cell body#GO:0043025;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cell body#GO:0044297;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;distal axon#GO:0150034;cell projection#GO:0042995;cytoskeleton#GO:0005856;growth cone#GO:0030426;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 myelin protein#PC00161 HUMAN|HGNC=20415|UniProtKB=Q8NBJ7 Q8NBJ7 SUMF2 PTHR23150:SF33 SULFATASE MODIFYING FACTOR 1, 2 INACTIVE C-ALPHA-FORMYLGLYCINE-GENERATING ENZYME 2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=19895|UniProtKB=Q96PP8 Q96PP8 GBP5 PTHR10751:SF40 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 5 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 heterotrimeric G-protein#PC00117 HUMAN|HGNC=35164|UniProtKB=Q8TAD7 Q8TAD7 OCC1 PTHR38502:SF1 OVEREXPRESSED IN COLON CARCINOMA 1 PROTEIN OVEREXPRESSED IN COLON CARCINOMA 1 PROTEIN HUMAN|HGNC=26614|UniProtKB=Q8NB46 Q8NB46 ANKRD52 PTHR24123:SF70 ANKYRIN REPEAT-CONTAINING SERINE/THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY ANKYRIN REPEAT SUBUNIT C scaffold/adaptor protein#PC00226 HUMAN|HGNC=19864|UniProtKB=Q9UKI9 Q9UKI9 POU2F3 PTHR11636:SF81 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=7713|UniProtKB=O75380 O75380 NDUFS6 PTHR13156:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=15861|UniProtKB=Q9H5Z1 Q9H5Z1 DHX35 PTHR18934:SF136 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX35-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA helicase#PC00032 HUMAN|HGNC=28530|UniProtKB=Q8TAV0 Q8TAV0 FAM76A PTHR46176:SF2 LD21662P PROTEIN FAM76A HUMAN|HGNC=21636|UniProtKB=Q6ZU52 Q6ZU52 KIAA0408 PTHR15705:SF1 MCG7194, ISOFORM CRA_A DUF4482 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=28495|UniProtKB=Q8IZ20 Q8IZ20 ZNF683 PTHR24390:SF124 ZINC FINGER PROTEIN TISSUE-RESIDENT T-CELL TRANSCRIPTION REGULATOR PROTEIN ZNF683 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;organic cyclic compound binding#GO:0097159;transcription corepressor activity#GO:0003714;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=16407|UniProtKB=Q8NFV4 Q8NFV4 ABHD11 PTHR46118:SF4 FAMILY NOT NAMED PROTEIN ABHD11 HUMAN|HGNC=14862|UniProtKB=P0CAP2 P0CAP2 POLR2M PTHR23171:SF5 GDOWN1 DNA-DIRECTED RNA POLYMERASE II SUBUNIT GRINL1A-RELATED cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nuclear envelope#GO:0005635;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;cytoplasm#GO:0005737;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;plasma membrane#GO:0005886 HUMAN|HGNC=21731|UniProtKB=Q8N0Y7 Q8N0Y7 PGAM4 PTHR11931:SF14 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE 4-RELATED mutase#PC00160 Glycolysis#P00024>Phosphoglyceromutase#P00680 HUMAN|HGNC=497|UniProtKB=O75762 O75762 TRPA1 PTHR24123:SF124 ANKYRIN REPEAT-CONTAINING TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY A MEMBER 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=12220|UniProtKB=A0A0A0MS03 A0A0A0MS03 TRBV5-3 PTHR23268:SF6 T-CELL RECEPTOR BETA CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=3681|UniProtKB=P11487 P11487 FGF3 PTHR11486:SF26 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 3 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=17843|UniProtKB=Q96RS0 Q96RS0 TGS1 PTHR14741:SF32 S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED TRIMETHYLGUANOSINE SYNTHASE RNA methyltransferase#PC00033 HUMAN|HGNC=29148|UniProtKB=P0C2W1 P0C2W1 FBXO45 PTHR12245:SF7 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN F-BOX/SPRY DOMAIN-CONTAINING PROTEIN 1 cellular component biogenesis#GO:0044085;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;nervous system development#GO:0007399;modification-dependent macromolecule catabolic process#GO:0043632;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;cell junction assembly#GO:0034329;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;cellular protein catabolic process#GO:0044257;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 SCF ubiquitin ligase complex#GO:0019005;synapse#GO:0045202;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell junction#GO:0030054;cellular anatomical entity#GO:0110165 HUMAN|HGNC=29478|UniProtKB=Q9GZN7 Q9GZN7 ROGDI PTHR13618:SF1 LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1 PROTEIN ROGDI HOMOLOG pH reduction#GO:0045851;regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;vacuolar acidification#GO:0007035;regulation of cellular pH#GO:0030641 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=9831|UniProtKB=P15918 P15918 RAG1 PTHR11539:SF0 VDJ RECOMBINATION ACTIVATING PROTEIN 1 RAG1 V(D)J RECOMBINATION-ACTIVATING PROTEIN 1 endodeoxyribonuclease#PC00093 HUMAN|Gene=YM012_HUMAN|UniProtKB=Q9UF83 Q9UF83 - PTHR35683:SF7 YALI0C04136P APPLE DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=18688|UniProtKB=Q5IJ48 Q5IJ48 CRB2 PTHR24049:SF19 CRUMBS FAMILY MEMBER PROTEIN CRUMBS HOMOLOG 2 establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;establishment or maintenance of bipolar cell polarity#GO:0061245 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=11693|UniProtKB=Q5JU00 Q5JU00 TCTE1 PTHR24107:SF20 YNEIN REGULATORY COMPLEX SUBUNIT 5 DYNEIN REGULATORY COMPLEX SUBUNIT 5 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=3121|UniProtKB=Q66K89 Q66K89 E4F1 PTHR24390:SF94 ZINC FINGER PROTEIN TRANSCRIPTION FACTOR E4F1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=31907|UniProtKB=P0CL81 P0CL81 GAGE12G PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=30692|UniProtKB=Q6P9F7 Q6P9F7 LRRC8B PTHR45752:SF40 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8B hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9294|UniProtKB=O95685 O95685 PPP1R3D PTHR12307:SF4 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3D phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase 1 binding#GO:0008157;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 monosaccharide metabolic process#GO:0005996;glucan metabolic process#GO:0044042;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;energy derivation by oxidation of organic compounds#GO:0015980;regulation of biological process#GO:0050789;cellular glucan metabolic process#GO:0006073;glucan biosynthetic process#GO:0009250;regulation of biosynthetic process#GO:0009889;oxidation-reduction process#GO:0055114;regulation of macromolecule biosynthetic process#GO:0010556;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;glycogen biosynthetic process#GO:0005978;regulation of glucose metabolic process#GO:0010906;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;polysaccharide metabolic process#GO:0005976;regulation of cellular biosynthetic process#GO:0031326;cellular carbohydrate metabolic process#GO:0044262;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;hexose metabolic process#GO:0019318;energy reserve metabolic process#GO:0006112;cellular polysaccharide biosynthetic process#GO:0033692;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular polysaccharide metabolic process#GO:0044264;small molecule metabolic process#GO:0044281 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 phosphatase modulator#PC00184 HUMAN|HGNC=19710|UniProtKB=Q96JK4 Q96JK4 HHIPL1 PTHR19328:SF32 HEDGEHOG-INTERACTING PROTEIN HHIP-LIKE PROTEIN 1 protein-binding activity modulator#PC00095 HUMAN|HGNC=20880|UniProtKB=Q86UL3 Q86UL3 GPAT4 PTHR23063:SF37 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4 acyltransferase#PC00042 HUMAN|HGNC=19960|UniProtKB=Q9BVV6 Q9BVV6 KIAA0586 PTHR15721:SF2 KIAA0586 PROTEIN PROTEIN TALPID3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=8140|UniProtKB=O60313 O60313 OPA1 PTHR11566:SF67 DYNAMIN DYNAMIN-LIKE 120 KDA PROTEIN, MITOCHONDRIAL GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;microtubule binding#GO:0008017;nucleoside-triphosphatase activity#GO:0017111 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;membrane fission#GO:0090148;membrane organization#GO:0061024;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996;protein polymerization#GO:0051258;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266;protein-containing complex subunit organization#GO:0043933 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 HUMAN|HGNC=11110|UniProtKB=O14497 O14497 ARID1A PTHR12656:SF12 BRG-1 ASSOCIATED FACTOR 250 BAF250 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1A nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=15765|UniProtKB=O95396 O95396 MOCS3 PTHR10953:SF102 UBIQUITIN-ACTIVATING ENZYME E1 ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=30006|UniProtKB=Q9H6Y5 Q9H6Y5 MAGIX PTHR47646:SF1 PDZ DOMAIN-CONTAINING PROTEIN MAGIX PDZ DOMAIN-CONTAINING PROTEIN MAGIX HUMAN|HGNC=30091|UniProtKB=Q96QH2 Q96QH2 PRAM1 PTHR16830:SF11 SH2 CONTAINING ADAPTOR PRAM-1 RELATED PML-RARA-REGULATED ADAPTER MOLECULE 1 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular localization#GO:0051641;signal transduction#GO:0007165;activation of immune response#GO:0002253;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;integrin-mediated signaling pathway#GO:0007229;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;signaling#GO:0023052;protein localization to plasma membrane#GO:0072659;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;protein localization to membrane#GO:0072657;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=10918|UniProtKB=Q13336 Q13336 SLC14A1 PTHR10464:SF5 UREA TRANSPORTER UREA TRANSPORTER 1 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 transporter#PC00227 HUMAN|HGNC=51793|UniProtKB=A0A0U1RQI7 A0A0U1RQI7 KLF18 PTHR23235:SF85 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUPPEL-LIKE FACTOR 18 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4247|UniProtKB=P38435 P38435 GGCX PTHR12639:SF6 VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=17841|UniProtKB=Q5VZ52 Q5VZ52 MORN5 PTHR46437:SF1 MORN REPEAT-CONTAINING PROTEIN 5 MORN REPEAT-CONTAINING PROTEIN 5 HUMAN|HGNC=1888|UniProtKB=Q9UFW8 Q9UFW8 CGGBP1 PTHR32344:SF1 U1-TYPE DOMAIN-CONTAINING PROTEIN U1-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=29797|UniProtKB=Q8NFH5 Q8NFH5 NUP35 PTHR21527:SF6 NUCLEOPORIN NUP35 NUCLEOPORIN NUP35 nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein import#GO:0017038;nuclear transport#GO:0051169;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;protein transport#GO:0015031;aromatic compound biosynthetic process#GO:0019438;intracellular transport#GO:0046907;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;biosynthetic process#GO:0009058;amide transport#GO:0042886;protein import into nucleus#GO:0006606;regulation of transcription, DNA-templated#GO:0006355;organic substance transport#GO:0071702;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;protein localization to organelle#GO:0033365;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;establishment of protein localization to organelle#GO:0072594;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;nucleocytoplasmic transport#GO:0006913;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear pore central transport channel#GO:0044613;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=22234|UniProtKB=Q8WZ19 Q8WZ19 KCTD13 PTHR11145:SF18 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 1 transferase activity#GO:0016740;Ras GTPase binding#GO:0017016;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;GTP-Rho binding#GO:0017049;small GTPase binding#GO:0031267;catalytic activity, acting on a protein#GO:0140096;Rho GTPase binding#GO:0017048 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;negative regulation of Ras protein signal transduction#GO:0046580;regulation of intracellular signal transduction#GO:1902531;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;negative regulation of small GTPase mediated signal transduction#GO:0051058;catabolic process#GO:0009056;intracellular signal transduction#GO:0035556;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;primary metabolic process#GO:0044238;regulation of small GTPase mediated signal transduction#GO:0051056;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of Ras protein signal transduction#GO:0046578 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11386|UniProtKB=Q13586 Q13586 STIM1 PTHR15136:SF9 STROMAL INTERACTION MOLECULE HOMOLOG STROMAL INTERACTION MOLECULE 1 cation binding#GO:0043169;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;molecular function regulator#GO:0098772;ion binding#GO:0043167;channel regulator activity#GO:0016247;transporter activity#GO:0005215;channel activity#GO:0015267 positive regulation of ion transport#GO:0043270;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of molecular function#GO:0044093;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;regulation of molecular function#GO:0065009;positive regulation of transmembrane transport#GO:0034764;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;cellular cation homeostasis#GO:0030003;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;regulation of calcium ion transport#GO:0051924;homeostatic process#GO:0042592;positive regulation of ion transmembrane transporter activity#GO:0032414;positive regulation of transport#GO:0051050;cation homeostasis#GO:0055080;positive regulation of calcium ion transport#GO:0051928;chemical homeostasis#GO:0048878;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of ion transmembrane transport#GO:0034765;positive regulation of transporter activity#GO:0032411;regulation of cellular process#GO:0050794;positive regulation of ion transmembrane transport#GO:0034767;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=26714|UniProtKB=Q8TED9 Q8TED9 AFAP1L1 PTHR14338:SF1 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1-LIKE 1 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=26060|UniProtKB=Q6NUN0 Q6NUN0 ACSM5 PTHR43605:SF6 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM5, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 HUMAN|HGNC=11030|UniProtKB=Q9Y6R1 Q9Y6R1 SLC4A4 PTHR11453:SF10 ANION EXCHANGE PROTEIN ELECTROGENIC SODIUM BICARBONATE COTRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=17325|UniProtKB=Q9UF12 Q9UF12 PRODH2 PTHR13914:SF29 PROLINE OXIDASE HYDROXYPROLINE DEHYDROGENASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidase#PC00175 Huntington disease#P00029>Proline oxidase#G01529 HUMAN|HGNC=4404|UniProtKB=P59768 P59768 GNG2 PTHR13809:SF25 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-2 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;CCKR signaling map#P06959>Gbeta/gamma#P07197;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Nicotine pharmacodynamics pathway#P06587>GNG#P06590;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Gonadotropin-releasing hormone receptor pathway#P06664>Ggamma#P06754;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 HUMAN|HGNC=8993|UniProtKB=P12273 P12273 PIP PTHR15096:SF5 PROLACTIN-INDUCIBLE PROTEIN/SEMINAL VESICLE ANTIGEN PROLACTIN-INDUCIBLE PROTEIN hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;immune system process#GO:0002376;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;organonitrogen compound metabolic process#GO:1901564;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=9004|UniProtKB=P78337 P78337 PITX1 PTHR45882:SF1 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>PITX#P06722 HUMAN|HGNC=8556|UniProtKB=Q9H361 Q9H361 PABPC3 PTHR24012:SF680 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 3 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|Ensembl=ENSG00000236543|UniProtKB=A0A1B0GUV8 A0A1B0GUV8 LOC102723971 PTHR11430:SF120 LIPOCALIN LIPOCLN_CYTOSOLIC_FA-BD_DOM DOMAIN-CONTAINING PROTEIN transfer/carrier protein#PC00219 HUMAN|HGNC=14698|UniProtKB=P0DMU2 P0DMU2 OR8G3P PTHR48018:SF172 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8G3 PSEUDOGENE-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=27344|UniProtKB=A2RU14 A2RU14 TMEM218 PTHR31622:SF1 TRANSMEMBRANE PROTEIN 218 TRANSMEMBRANE PROTEIN 218 HUMAN|HGNC=17127|UniProtKB=Q9NP94 Q9NP94 SLC39A2 PTHR11040:SF120 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP2 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;transition metal ion transport#GO:0000041;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=24560|UniProtKB=Q9Y3X0 Q9Y3X0 CCDC9 PTHR15635:SF11 COILED-COIL DOMAIN CONTAINING PROTEIN 9 COILED-COIL DOMAIN-CONTAINING PROTEIN 9 HUMAN|HGNC=18234|UniProtKB=Q96EN8 Q96EN8 MOCOS PTHR14237:SF80 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MOLYBDENUM COFACTOR SULFURASE HUMAN|HGNC=7852|UniProtKB=O00746 O00746 NME4 PTHR11349:SF49 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 HUMAN|HGNC=26618|UniProtKB=P0C025 P0C025 NUDT17 PTHR42904:SF1 NUDIX HYDROLASE, NUDC SUBFAMILY NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 17 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;nucleotide diphosphatase activity#GO:0004551 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;NADP metabolic process#GO:0006739;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 HUMAN|HGNC=26995|UniProtKB=Q0VGE8 Q0VGE8 ZNF816 PTHR24377:SF911 IP01015P-RELATED ZINC FINGER PROTEIN 816 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=13709|UniProtKB=O15121 O15121 DEGS1 PTHR12879:SF2 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE DES1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 hydroxylase#PC00122 HUMAN|HGNC=19299|UniProtKB=Q86T03 Q86T03 PIP4P1 PTHR21014:SF2 UNCHARACTERIZED TYPE 1 PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 4-PHOSPHATASE HUMAN|HGNC=23520|UniProtKB=Q7RTY1 Q7RTY1 SLC16A9 PTHR11360:SF158 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 9 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=14471|UniProtKB=Q86WA9 Q86WA9 SLC26A11 PTHR11814:SF55 SULFATE TRANSPORTER SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;transmembrane transporter activity#GO:0022857;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;active ion transmembrane transporter activity#GO:0022853 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=28429|UniProtKB=Q9H819 Q9H819 DNAJC18 PTHR43908:SF2 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 18 heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488;Hsp70 protein binding#GO:0030544 cellular response to misfolded protein#GO:0071218;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;chaperone-mediated protein folding#GO:0061077;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;cellular protein catabolic process#GO:0044257;response to topologically incorrect protein#GO:0035966;'de novo' protein folding#GO:0006458;ubiquitin-dependent ERAD pathway#GO:0030433;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=9721|UniProtKB=P32322 P32322 PYCR1 PTHR11645:SF6 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE 1, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 reductase#PC00198 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 HUMAN|HGNC=23797|UniProtKB=Q9BXR0 Q9BXR0 QTRT1 PTHR43530:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA processing factor#PC00147 HUMAN|HGNC=12541|UniProtKB=O60656 O60656 UGT1A9 PTHR48050:SF6 STEROL 3-BETA-GLUCOSYLTRANSFERASE UDP-GLUCURONOSYLTRANSFERASE 1A10-RELATED glycosyltransferase#PC00111 HUMAN|HGNC=9682|UniProtKB=O14522 O14522 PTPRT PTHR19134:SF208 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE T hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=44672|UniProtKB=P0DMB2 P0DMB2 C8orf88 PTHR12669:SF15 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN GRANULITO protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;regulation of translational initiation#GO:0006446;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;translational initiation#GO:0006413;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=15558|UniProtKB=Q8WYQ4 Q8WYQ4 C22orf15 PTHR33887:SF1 FAMILY NOT NAMED GENE 867-RELATED HUMAN|HGNC=25284|UniProtKB=Q494U1 Q494U1 PLEKHN1 PTHR46882:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY N MEMBER 1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY N MEMBER 1 binding#GO:0005488;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;regulation of cellular amide metabolic process#GO:0034248;response to abiotic stimulus#GO:0009628;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;response to decreased oxygen levels#GO:0036293;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;peptide biosynthetic process#GO:0043043;negative regulation of translation#GO:0017148;response to stress#GO:0006950;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;response to hypoxia#GO:0001666;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;biosynthetic process#GO:0009058;cellular nitrogen compound catabolic process#GO:0044270;translation#GO:0006412;organic cyclic compound metabolic process#GO:1901360;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;cell death#GO:0008219;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;response to oxygen levels#GO:0070482;cellular catabolic process#GO:0044248;positive regulation of apoptotic process#GO:0043065;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;regulation of cellular catabolic process#GO:0031329;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell death#GO:0010941;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254;cellular macromolecule catabolic process#GO:0044265;positive regulation of cell death#GO:0010942;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 envelope#GO:0031975;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 HUMAN|HGNC=4589|UniProtKB=Q7Z429 Q7Z429 GRINA PTHR23291:SF16 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 1 Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 HUMAN|HGNC=14458|UniProtKB=Q9UQC2 Q9UQC2 GAB2 PTHR45960:SF1 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 2 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Grb2#P01148;EGF receptor signaling pathway#P00018>Gab#P00563 HUMAN|HGNC=21750|UniProtKB=Q96L11 Q96L11 LLCFC1 PTHR37348:SF1 LLLL AND CFNLAS MOTIF-CONTAINING PROTEIN 1 LLLL AND CFNLAS MOTIF-CONTAINING PROTEIN 1 HUMAN|HGNC=3498|UniProtKB=Q03112 Q03112 MECOM PTHR24393:SF69 ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE MECOM DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23421|UniProtKB=Q8TCA0 Q8TCA0 LRRC20 PTHR16083:SF2 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 20 HUMAN|HGNC=27293|UniProtKB=C9JUS6 C9JUS6 ADM5 PTHR23414:SF6 ADRENOMEDULLIN, ADM ADRENOMEDULLIN-5-LIKE PROTEIN-RELATED peptide hormone#PC00179 HUMAN|HGNC=14799|UniProtKB=Q8NH60 Q8NH60 OR52J3 PTHR26450:SF355 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52J3 transmembrane signal receptor#PC00197 HUMAN|HGNC=6880|UniProtKB=Q13164 Q13164 MAPK7 PTHR24055:SF158 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 7 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>MAPK7#P07021;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Interleukin signaling pathway#P00036>ERK#P00965;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;FGF signaling pathway#P00021>ERK1-2#P00627;PDGF signaling pathway#P00047>ERK#P01143;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Apoptosis signaling pathway#P00006>MAPK#P00269;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Parkinson disease#P00049>ERK#P01211;Endothelin signaling pathway#P00019>ERK#P00566 HUMAN|HGNC=20529|UniProtKB=P59990 P59990 KRTAP12-1 PTHR23262:SF180 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 12-1-RELATED HUMAN|HGNC=19768|UniProtKB=Q96NS5 Q96NS5 ASB16 PTHR24118:SF72 POTE ANKYRIN DOMAIN ANKYRIN REPEAT AND SOCS BOX PROTEIN 16 membrane traffic protein#PC00150 HUMAN|HGNC=22192|UniProtKB=Q12765 Q12765 SCRN1 PTHR12994:SF7 SECERNIN SECERNIN-1 HUMAN|HGNC=43430|UniProtKB=A0A096LP01 A0A096LP01 SMIM26 PTHR40386:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 26 SMALL INTEGRAL MEMBRANE PROTEIN 26 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=1973|UniProtKB=Q9GZS9 Q9GZS9 CHST5 PTHR10704:SF13 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 5 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;amino sugar metabolic process#GO:0006040;aminoglycan metabolic process#GO:0006022;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=8959|UniProtKB=Q92521 Q92521 PIGB PTHR22760:SF4 GLYCOSYLTRANSFERASE GPI MANNOSYLTRANSFERASE 3 transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 HUMAN|HGNC=19355|UniProtKB=Q6NYC1 Q6NYC1 JMJD6 PTHR12480:SF32 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6 protein modifying enzyme#PC00260 HUMAN|HGNC=14173|UniProtKB=Q9UJJ7 Q9UJJ7 RPUSD1 PTHR21600:SF34 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA processing factor#PC00147 HUMAN|HGNC=15881|UniProtKB=Q9BQY9 Q9BQY9 DBNDD2 PTHR16294:SF7 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN DOMAIN-CONTAINING PROTEIN 2 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;negative regulation of protein kinase activity#GO:0006469;negative regulation of transferase activity#GO:0051348;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;protein phosphorylation#GO:0006468;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=16260|UniProtKB=Q8IXA5 Q8IXA5 SPACA3 PTHR11407:SF25 LYSOZYME C SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 3 plasma membrane fusion#GO:0045026;fertilization#GO:0009566;membrane organization#GO:0061024;multicellular organism reproduction#GO:0032504;cellular process involved in reproduction in multicellular organism#GO:0022412;single fertilization#GO:0007338;cellular component organization#GO:0016043;cellular process#GO:0009987;multi-organism process#GO:0051704;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;reproduction#GO:0000003;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703 supramolecular complex#GO:0099080;axoneme#GO:0005930;acrosomal vesicle#GO:0001669;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;cytoplasmic microtubule#GO:0005881;vacuole#GO:0005773;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;B axonemal microtubule#GO:0097650;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;intracellular vesicle#GO:0097708;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;cytoplasmic vesicle#GO:0031410;dynein complex#GO:0030286;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 HUMAN|HGNC=23762|UniProtKB=Q8WXT5 Q8WXT5 FOXD4L4 PTHR11829:SF381 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-LIKE 3-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=30134|UniProtKB=Q8IZL8 Q8IZL8 PELP1 PTHR34105:SF1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 HUMAN|HGNC=5838|UniProtKB=A0A0C4DH26 A0A0C4DH26 IGKV6D-41 PTHR23267:SF217 IMMUNOGLOBULIN LIGHT CHAIN NON-FUNCTIONAL IMMUNOGLOBULIN KAPPA VARIABLE 6D-41-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=18381|UniProtKB=Q8IV01 Q8IV01 SYT12 PTHR10024:SF252 SYNAPTOTAGMIN SYNAPTOTAGMIN-12 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;syntaxin binding#GO:0019905;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cation transport#GO:0006812;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;response to metal ion#GO:0010038;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of ion transport#GO:0043269;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 HUMAN|HGNC=2438|UniProtKB=P09919 P09919 CSF3 PTHR10511:SF2 GRANULOCYTE COLONY-STIMULATING FACTOR GRANULOCYTE COLONY-STIMULATING FACTOR HUMAN|HGNC=19183|UniProtKB=Q9P1Z3 Q9P1Z3 HCN3 PTHR45689:SF7 I[[H]] CHANNEL, ISOFORM E POTASSIUM/SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 3 ion channel#PC00133 HUMAN|HGNC=18379|UniProtKB=Q86VW0 Q86VW0 SESTD1 PTHR46607:SF1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 HUMAN|HGNC=29849|UniProtKB=Q8N3J6 Q8N3J6 CADM2 PTHR45889:SF1 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 2 HUMAN|HGNC=4795|UniProtKB=O95479 O95479 H6PD PTHR23429:SF7 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GDH/6PGL ENDOPLASMIC BIFUNCTIONAL PROTEIN dehydrogenase#PC00092 HUMAN|HGNC=29141|UniProtKB=O94967 O94967 WDR47 PTHR19863:SF5 NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG WD REPEAT-CONTAINING PROTEIN 47 HUMAN|Gene=MRUPP_HUMAN|UniProtKB=B2RBV5 B2RBV5 - PTHR31324:SF3 MORF4 FAMILY-ASSOCIATED PROTEIN 1-RELATED MORF4 FAMILY-ASSOCIATED PROTEIN 1-LIKE PROTEIN UPP-RELATED HUMAN|HGNC=18754|UniProtKB=Q96EF6 Q96EF6 FBXO17 PTHR12125:SF7 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 17 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 HUMAN|HGNC=3683|UniProtKB=P12034 P12034 FGF5 PTHR11486:SF23 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 5 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=5215|UniProtKB=P56937 P56937 HSD17B7 PTHR44442:SF1 3-KETO-STEROID REDUCTASE 3-KETO-STEROID REDUCTASE/17-BETA-HYDROXYSTEROID DEHYDROGENASE 7 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 reductase#PC00198 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 HUMAN|HGNC=1164|UniProtKB=P61165 P61165 TMEM258 PTHR13636:SF0 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 258 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226 HUMAN|HGNC=26994|UniProtKB=Q6PI98 Q6PI98 INO80C PTHR31200:SF1 INO80 COMPLEX SUBUNIT C INO80 COMPLEX SUBUNIT C cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 HUMAN|HGNC=5099|UniProtKB=P49639 P49639 HOXA1 PTHR45946:SF3 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-A1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=8723|UniProtKB=P05154 P05154 SERPINA5 PTHR11461:SF274 SERINE PROTEASE INHIBITOR, SERPIN PLASMA SERINE PROTEASE INHIBITOR serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=17947|UniProtKB=Q5T1C6 Q5T1C6 THEM4 PTHR12418:SF19 ACYL-COENZYME A THIOESTERASE THEM4 ACYL-COENZYME A THIOESTERASE THEM4 esterase#PC00097 HUMAN|HGNC=71|UniProtKB=Q9UG63 Q9UG63 ABCF2 PTHR19211:SF15 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 translation elongation factor#PC00222 HUMAN|HGNC=29657|UniProtKB=Q8N108 Q8N108 MIER1 PTHR10865:SF24 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 1 repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 HUMAN|HGNC=25528|UniProtKB=Q9NVZ3 Q9NVZ3 NECAP2 PTHR12847:SF16 ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED ADAPTIN EAR-BINDING COAT-ASSOCIATED PROTEIN 2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;vesicle coat#GO:0030120;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;protein-containing complex#GO:0032991;membrane coat#GO:0030117;intracellular#GO:0005622;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=22785|UniProtKB=A8MUV8 A8MUV8 ZNF727 PTHR24384:SF206 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 727-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=11097|UniProtKB=P28370 P28370 SMARCA1 PTHR10799:SF819 SNF2/RAD54 HELICASE FAMILY GLOBAL TRANSCRIPTION ACTIVATOR SNF2L1-RELATED pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=5757|UniProtKB=A0A075B6H8 A0A075B6H8 IGKV1D-42 PTHR23267:SF388 IMMUNOGLOBULIN LIGHT CHAIN NON-FUNCTIONAL IMMUNOGLOBULIN KAPPA VARIABLE 1D-42-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=5730|UniProtKB=A0A0C4DH73 A0A0C4DH73 IGKV1-12 PTHR23267:SF474 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-12-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|Ensembl=ENSG00000229674|UniProtKB=A0A3B3IU63 A0A3B3IU63 H2AL1RP PTHR23430:SF11 HISTONE H2A HISTONE H2A heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=42956|UniProtKB=E9PQ53 E9PQ53 NDUFC2-KCTD14 PTHR13099:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B14.5B NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C2-RELATED envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=1954|UniProtKB=P08912 P08912 CHRM5 PTHR24247:SF209 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M5 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;organic cyclic compound binding#GO:0097159;acetylcholine receptor activity#GO:0015464;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;acetylcholine binding#GO:0042166;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;negative regulation of intracellular signal transduction#GO:1902532;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;negative regulation of catalytic activity#GO:0043086;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935;negative regulation of molecular function#GO:0044092 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=8734|UniProtKB=Q9BW27 Q9BW27 NUP85 PTHR13373:SF21 FROUNT PROTEIN-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP85 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 positive regulation of gene expression#GO:0010628;cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;protein import#GO:0017038;positive regulation of biological process#GO:0048518;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;nuclear export#GO:0051168;regulation of cellular process#GO:0050794;protein transport#GO:0015031;aromatic compound biosynthetic process#GO:0019438;intracellular transport#GO:0046907;regulation of metabolic process#GO:0019222;protein-containing complex localization#GO:0031503;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;biosynthetic process#GO:0009058;ribonucleoprotein complex export from nucleus#GO:0071426;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;protein import into nucleus#GO:0006606;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;protein export from nucleus#GO:0006611;protein localization to organelle#GO:0033365;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;mRNA export from nucleus#GO:0006406;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;establishment of protein localization to organelle#GO:0072594;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;organic cyclic compound biosynthetic process#GO:1901362;mRNA transport#GO:0051028;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nucleocytoplasmic transport#GO:0006913;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;RNA export from nucleus#GO:0006405;regulation of cellular macromolecule biosynthetic process#GO:2000112;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 structural protein#PC00211 HUMAN|HGNC=29111|UniProtKB=O94854 O94854 KIAA0754 PTHR35248:SF2 PUTATIVE-RELATED PUTATIVE-RELATED HUMAN|HGNC=29117|UniProtKB=Q2TBF2 Q2TBF2 WSCD2 PTHR45964:SF3 WSCD FAMILY MEMBER CG9164 WSC DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=26625|UniProtKB=Q6NUS8 Q6NUS8 UGT3A1 PTHR48043:SF112 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 3A1 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=2013|UniProtKB=Q92572 Q92572 AP3S1 PTHR11753:SF12 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-3 COMPLEX SUBUNIT SIGMA-1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 HUMAN|HGNC=14467|UniProtKB=Q8TE54 Q8TE54 SLC26A7 PTHR11814:SF75 SULFATE TRANSPORTER ANION EXCHANGE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;inorganic anion transmembrane transporter activity#GO:0015103;active ion transmembrane transporter activity#GO:0022853 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=12816|UniProtKB=Q01831 Q01831 XPC PTHR12135:SF0 DNA REPAIR PROTEIN XP-C / RAD4 DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;nucleotide-excision repair complex#GO:0000109;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 damaged DNA-binding protein#PC00086 HUMAN|HGNC=32789|UniProtKB=Q6UXV0 Q6UXV0 GFRAL PTHR10269:SF1 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=23578|UniProtKB=Q9H8M7 Q9H8M7 MINDY3 PTHR12473:SF8 UNCHARACTERIZED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-3 hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 HUMAN|HGNC=20421|UniProtKB=Q8N448 Q8N448 LNX2 PTHR19964:SF33 MULTIPLE PDZ DOMAIN PROTEIN LIGAND OF NUMB PROTEIN X 2 Notch signaling pathway#P00045>LNXp80#P01111 HUMAN|HGNC=9353|UniProtKB=P32119 P32119 PRDX2 PTHR10681:SF161 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-2 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;cellular process#GO:0009987;cell activation#GO:0001775;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to oxidative stress#GO:0034599;catabolic process#GO:0009056;response to toxic substance#GO:0009636;cellular response to stress#GO:0033554;leukocyte activation#GO:0045321;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 peroxidase#PC00180 HUMAN|HGNC=11975|UniProtKB=Q16473 Q16473 TNXA PTHR46708:SF3 TENASCIN TENASCIN-X-RELATED extracellular matrix protein#PC00102 HUMAN|HGNC=29021|UniProtKB=O15078 O15078 CEP290 PTHR18879:SF20 CENTROSOMAL PROTEIN OF 290 KDA CENTROSOMAL PROTEIN OF 290 KDA HUMAN|HGNC=6130|UniProtKB=Q96AZ6 Q96AZ6 ISG20 PTHR12801:SF59 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED INTERFERON-STIMULATED GENE 20 KDA PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;defense response to virus#GO:0051607;organic substance catabolic process#GO:1901575;defense response#GO:0006952;immune effector process#GO:0002252;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;response to stress#GO:0006950;nucleic acid phosphodiester bond hydrolysis#GO:0090305;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 exoribonuclease#PC00099 HUMAN|HGNC=303|UniProtKB=Q8IUX7 Q8IUX7 AEBP1 PTHR11532:SF48 PROTEASE M14 CARBOXYPEPTIDASE ADIPOCYTE ENHANCER-BINDING PROTEIN 1 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;metallopeptidase activity#GO:0008237;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;peptidase activity#GO:0008233;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;protein processing#GO:0016485;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease#PC00190 HUMAN|HGNC=4456|UniProtKB=P43304 P43304 GPD2 PTHR11985:SF29 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 HUMAN|HGNC=11171|UniProtKB=Q9Y675 Q9Y675 SNURF PTHR14508:SF2 SNRPN UPSTREAM READING FRAME PROTEIN, SNURF SNRPN UPSTREAM READING FRAME PROTEIN-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear speck#GO:0016607;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6848|UniProtKB=Q13233 Q13233 MAP3K1 PTHR24361:SF414 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1 Integrin signalling pathway#P00034>ERK#P00907;Angiogenesis#P00005>MEKK1#P00208;Toll receptor signaling pathway#P00054>MEKK1#P01357;FGF signaling pathway#P00021>MEKK1-5#P00634;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;Apoptosis signaling pathway#P00006>MEKK1#P00291;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Ras Pathway#P04393>MEKK1/4#P04543;T cell activation#P00053>MEKK#P01297 HUMAN|HGNC=28125|UniProtKB=Q9BSU3 Q9BSU3 NAA11 PTHR23091:SF282 N-TERMINAL ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 11 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;N-acyltransferase activity#GO:0016410 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;N-terminal protein amino acid acetylation#GO:0006474;peptidyl-serine modification#GO:0018209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 acetyltransferase#PC00038 HUMAN|HGNC=1471|UniProtKB=P49069 P49069 CAMLG PTHR15026:SF0 CALCIUM-SIGNAL MODULATING CYCLOPHILIN LIGAND CAML CALCIUM SIGNAL-MODULATING CYCLOPHILIN LIGAND HUMAN|HGNC=29039|UniProtKB=Q5VT52 Q5VT52 RPRD2 PTHR12460:SF0 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 2 basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 kinase inhibitor#PC00139 HUMAN|HGNC=4112|UniProtKB=Q96GT9 Q96GT9 XAGE2 PTHR14047:SF35 P ANTIGEN FAMILY MEMBER 5-RELATED X ANTIGEN FAMILY MEMBER 2 HUMAN|HGNC=25352|UniProtKB=Q8N1W2 Q8N1W2 ZNF710 PTHR24390:SF43 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 710 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7803|UniProtKB=Q12986 Q12986 NFX1 PTHR12360:SF15 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 TRANSCRIPTIONAL REPRESSOR NF-X1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=25220|UniProtKB=Q9BV87 Q9BV87 CNPPD1 PTHR15615:SF108 UNCHARACTERIZED PROTEIN CNPPD1 HUMAN|HGNC=32007|UniProtKB=Q8IWB4 Q8IWB4 SPATA31A7 PTHR21859:SF55 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31A1-RELATED HUMAN|HGNC=28852|UniProtKB=Q8N0S2 Q8N0S2 SYCE1 PTHR21731:SF0 UNCHARACTERIZED SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=27537|UniProtKB=Q6P050 Q6P050 FBXL22 PTHR16134:SF1 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX AND LEUCINE-RICH PROTEIN 22 HUMAN|HGNC=9258|UniProtKB=Q9UNP9 Q9UNP9 PPIE PTHR11071:SF519 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=25393|UniProtKB=Q5EBM4 Q5EBM4 ZNF542P PTHR24377:SF829 IP01015P-RELATED ZINC FINGER PROTEIN 542-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2549|UniProtKB=Q92879 Q92879 CELF1 PTHR24012:SF686 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 HUMAN|HGNC=5351|UniProtKB=Q9Y6W8 Q9Y6W8 ICOS PTHR20904:SF0 INDUCIBLE T-CELL COSTIMULATOR ICOS INDUCIBLE T-CELL COSTIMULATOR regulation of cell-cell adhesion#GO:0022407;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;leukocyte cell-cell adhesion#GO:0007159;positive regulation of leukocyte activation#GO:0002696;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;system development#GO:0048731;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;lymphocyte activation#GO:0046649;immune system development#GO:0002520;multicellular organism development#GO:0007275;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of T cell activation#GO:0050870;positive regulation of cell adhesion#GO:0045785;positive regulation of cell activation#GO:0050867;positive regulation of cell-cell adhesion#GO:0022409 HUMAN|HGNC=1392|UniProtKB=Q15878 Q15878 CACNA1E PTHR45628:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT R-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1E metal ion transport#GO:0030001;ion transport#GO:0006811;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cation transport#GO:0006812;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;divalent metal ion transport#GO:0070838;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;divalent inorganic cation transport#GO:0072511;cell-cell signaling#GO:0007267;signaling#GO:0023052 voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 HUMAN|HGNC=14558|UniProtKB=Q9BXN2 Q9BXN2 CLEC7A PTHR47218:SF1 C-TYPE LECTIN DOMAIN FAMILY 7 MEMBER A C-TYPE LECTIN DOMAIN FAMILY 7 MEMBER A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;binding#GO:0005488 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;regulation of protein metabolic process#GO:0051246;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;detection of chemical stimulus#GO:0009593;positive regulation of cellular component movement#GO:0051272;positive regulation of lymphocyte activation#GO:0051251;regulation of vesicle-mediated transport#GO:0060627;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;regulation of wound healing#GO:0061041;regulation of cell migration#GO:0030334;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;positive regulation of cytokine production#GO:0001819;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;positive regulation of locomotion#GO:0040017;vesicle-mediated transport#GO:0016192;cellular response to biotic stimulus#GO:0071216;positive regulation of transport#GO:0051050;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;detection of stimulus#GO:0051606;cellular component organization#GO:0016043;positive regulation of inflammatory response#GO:0050729;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;response to wounding#GO:0009611;regulation of cellular process#GO:0050794;regulation of cytokine biosynthetic process#GO:0042035;regulation of defense response#GO:0031347;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;positive regulation of defense response#GO:0031349;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;cell recognition#GO:0008037;tumor necrosis factor production#GO:0032640;regulation of locomotion#GO:0040012;transport#GO:0006810;wound healing#GO:0042060;biosynthetic process#GO:0009058;cytokine production#GO:0001816;inflammatory response#GO:0006954;positive regulation of response to stimulus#GO:0048584;positive regulation of biosynthetic process#GO:0009891;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of cell motility#GO:2000147;positive regulation of macromolecule biosynthetic process#GO:0010557;vesicle organization#GO:0016050;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;positive regulation of wound healing#GO:0090303;regulation of response to external stimulus#GO:0032101;macromolecule biosynthetic process#GO:0009059;lymphocyte activation#GO:0046649;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular biosynthetic process#GO:0044249;cell motility#GO:0048870;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of response to wounding#GO:1903034;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of inflammatory response#GO:0050727;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of protein metabolic process#GO:0051247;regulation of leukocyte activation#GO:0002694;positive regulation of cell migration#GO:0030335;regulation of cellular biosynthetic process#GO:0031326;vesicle budding from membrane#GO:0006900;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;response to other organism#GO:0051707;biological regulation#GO:0065007;cell migration#GO:0016477 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|HGNC=9594|UniProtKB=P43116 P43116 PTGER2 PTHR11866:SF8 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP2 SUBTYPE signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;organic acid binding#GO:0043177;transmembrane signaling receptor activity#GO:0004888 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;response to lipid#GO:0033993;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of intracellular signal transduction#GO:1902531;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular cation homeostasis#GO:0030003;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to hormone#GO:0009725;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 HUMAN|HGNC=40027|UniProtKB=C9JTQ0 C9JTQ0 ANKRD63 PTHR24166:SF30 ROLLING PEBBLES, ISOFORM B ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 63 HUMAN|HGNC=13243|UniProtKB=Q8WVP7 Q8WVP7 LMBR1 PTHR12625:SF1 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR LIMB REGION 1 PROTEIN HOMOLOG signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=30419|UniProtKB=Q7Z5J1 Q7Z5J1 HSD11B1L PTHR44279:SF3 HYDROXYSTEROID (11-BETA) DEHYDROGENASE 1-LIKE B-RELATED HYDROXYSTEROID 11-BETA-DEHYDROGENASE 1-LIKE PROTEIN lipid binding#GO:0008289;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;steroid binding#GO:0005496 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;steroid catabolic process#GO:0006706;organic cyclic compound metabolic process#GO:1901360;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;lipid catabolic process#GO:0016042;organic substance catabolic process#GO:1901575;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092 HUMAN|HGNC=11937|UniProtKB=P32970 P32970 CD70 PTHR15152:SF0 CD70 ANTIGEN CD70 ANTIGEN extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;plasma membrane#GO:0005886 HUMAN|HGNC=4848|UniProtKB=O43613 O43613 HCRTR1 PTHR24241:SF30 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OREXIN RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=28756|UniProtKB=Q96GS6 Q96GS6 ABHD17A PTHR12277:SF52 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;macromolecule deacylation#GO:0098732;protein deacylation#GO:0035601;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;lipoprotein metabolic process#GO:0042157;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=17910|UniProtKB=Q9UI38 Q9UI38 PRSS50 PTHR24253:SF35 TRANSMEMBRANE PROTEASE SERINE THREONINE PROTEASE PRSS50-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=49760|UniProtKB=A0A3B3IRV3 A0A3B3IRV3 MCTS2P PTHR22798:SF11 MCT-1 PROTEIN MALIGNANT T-CELL-AMPLIFIED SEQUENCE cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 translation initiation factor#PC00224 HUMAN|HGNC=23656|UniProtKB=Q3ZCQ8 Q3ZCQ8 TIMM50 PTHR12210:SF3 NUCLEAR LIM INTERACTOR-INTERACTING FACTOR-RELATED MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM50 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=24514|UniProtKB=Q9BWD3 Q9BWD3 RTL8A PTHR15503:SF6 LDOC1 RELATED RETROTRANSPOSON GAG-LIKE PROTEIN 8A-RELATED intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25451|UniProtKB=Q1KMD3 Q1KMD3 HNRNPUL2 PTHR12381:SF66 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=16255|UniProtKB=O95932 O95932 TGM6 PTHR11590:SF50 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 6 transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular protein modification process#GO:0006464 transferase#PC00220 HUMAN|HGNC=6603|UniProtKB=Q8N149 Q8N149 LILRA2 PTHR11738:SF86 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 2 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=38|UniProtKB=O94911 O94911 ABCA8 PTHR19229:SF148 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 8 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=7656|UniProtKB=P13591 P13591 NCAM1 PTHR12231:SF239 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN NEURAL CELL ADHESION MOLECULE 1 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=24320|UniProtKB=Q71RC2 Q71RC2 LARP4 PTHR22792:SF48 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 4 RNA metabolism protein#PC00031 HUMAN|Ensembl=ENSG00000250782|UniProtKB=A0A1W2PPL8 A0A1W2PPL8 TAF11L14 PTHR13218:SF15 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TAF11-LIKE PROTEIN ENSP00000332601-RELATED transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=21393|UniProtKB=Q9Y3V2 Q9Y3V2 RWDD3 PTHR15628:SF1 RWD DOMAIN-CONTAINING PROTEIN 3 RWD DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=30689|UniProtKB=O75155 O75155 CAND2 PTHR12696:SF2 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 2 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=12619|UniProtKB=Q9Y2K6 Q9Y2K6 USP20 PTHR21646:SF13 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 20 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=28303|UniProtKB=A5D8V7 A5D8V7 CCDC151 PTHR46518:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 151 COILED-COIL DOMAIN-CONTAINING PROTEIN 151 HUMAN|HGNC=25548|UniProtKB=Q9NVR2 Q9NVR2 INTS10 PTHR16055:SF2 UNCHARACTERIZED INTEGRATOR COMPLEX SUBUNIT 10 HUMAN|HGNC=33724|UniProtKB=Q8ND94 Q8ND94 LRRN4CL PTHR24366:SF143 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LRRN4 C-TERMINAL-LIKE PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=649|UniProtKB=P48444 P48444 ARCN1 PTHR10121:SF0 COATOMER SUBUNIT DELTA COATOMER SUBUNIT DELTA localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;COPI vesicle coat#GO:0030126;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=9892|UniProtKB=O75884 O75884 RBBP9 PTHR15394:SF3 FAMILY NOT NAMED SERINE HYDROLASE RBBP9 HUMAN|HGNC=26643|UniProtKB=Q6IQ49 Q6IQ49 SDE2 PTHR12786:SF1 SPLICING FACTOR SF3A-RELATED REPLICATION STRESS RESPONSE REGULATOR SDE2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=24193|UniProtKB=Q8TD86 Q8TD86 CALML6 PTHR23050:SF417 CALCIUM BINDING PROTEIN CALMODULIN-LIKE PROTEIN 6 cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;molecular function regulator#GO:0098772;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 calmodulin-related#PC00061 HUMAN|HGNC=1192|UniProtKB=Q9H2W6 Q9H2W6 MRPL46 PTHR13124:SF12 39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED 39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=25460|UniProtKB=Q96I82 Q96I82 KAZALD1 PTHR14186:SF21 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED KAZAL-TYPE SERINE PROTEASE INHIBITOR DOMAIN-CONTAINING PROTEIN 1 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular region#GO:0005576 HUMAN|HGNC=13949|UniProtKB=Q9UIM3 Q9UIM3 FKBPL PTHR43811:SF52 FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA FK506-BINDING PROTEIN-LIKE chaperone#PC00072 HUMAN|HGNC=1163|UniProtKB=Q9H5F2 Q9H5F2 C11orf1 PTHR34524:SF1 CALCYPHOSIN UPF0686 PROTEIN C11ORF1 calmodulin-related#PC00061 HUMAN|HGNC=14438|UniProtKB=Q53TS8 Q53TS8 C2CD6 PTHR21665:SF2 UNCHARACTERIZED C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 6 HUMAN|HGNC=21209|UniProtKB=A6NKF2 A6NKF2 ARID3C PTHR15348:SF2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3C nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=28542|UniProtKB=Q8N4F4 Q8N4F4 SLC22A24 PTHR24064:SF591 SOLUTE CARRIER FAMILY 22 MEMBER STEROID TRANSMEMBRANE TRANSPORTER SLC22A24 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258 HUMAN|HGNC=1057|UniProtKB=P51451 P51451 BLK PTHR24418:SF181 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BLK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;organelle localization#GO:0051640;activation of immune response#GO:0002253;organelle membrane fusion#GO:0090174;regulation of localization#GO:0032879;B cell proliferation#GO:0042100;nervous system development#GO:0007399;regulation of biological process#GO:0050789;peptidyl-tyrosine phosphorylation#GO:0018108;secretion#GO:0046903;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;establishment of organelle localization#GO:0051656;leukocyte activation#GO:0045321;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;cell adhesion#GO:0007155;cellular response to DNA damage stimulus#GO:0006974;cell activation involved in immune response#GO:0002263;negative regulation of leukocyte activation#GO:0002695;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell activation#GO:0001775;cellular component organization or biogenesis#GO:0071840;leukocyte differentiation#GO:0002521;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;export from cell#GO:0140352;signal transduction#GO:0007165;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;platelet activation#GO:0030168;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;biological adhesion#GO:0022610;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of programmed cell death#GO:0043068;cell death#GO:0008219;neuron differentiation#GO:0030182;vesicle organization#GO:0016050;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;immune effector process#GO:0002252;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;hemostasis#GO:0007599;negative regulation of cell activation#GO:0050866;regulation of response to wounding#GO:1903034;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;membrane fusion#GO:0061025;regulation of mononuclear cell proliferation#GO:0032944;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;regulation of lymphocyte proliferation#GO:0050670;regulation of cell death#GO:0010941;negative regulation of lymphocyte activation#GO:0051250;blood coagulation#GO:0007596;positive regulation of cell death#GO:0010942;regulation of B cell proliferation#GO:0030888;response to external biotic stimulus#GO:0043207;antigen receptor-mediated signaling pathway#GO:0050851;cellular localization#GO:0051641;cell projection organization#GO:0030030;regulation of cell-cell adhesion#GO:0022407;membrane organization#GO:0061024;regulation of coagulation#GO:0050818;homotypic cell-cell adhesion#GO:0034109;regulation of secretion by cell#GO:1903530;B cell receptor signaling pathway#GO:0050853;cell population proliferation#GO:0008283;plasma membrane bounded cell projection organization#GO:0120036;regulation of vesicle-mediated transport#GO:0060627;lysosome localization#GO:0032418;regulation of cell activation#GO:0050865;regulated exocytosis#GO:0045055;positive regulation of immune response#GO:0050778;regulation of wound healing#GO:0061041;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of secretion#GO:0051046;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;regulation of exocytosis#GO:0017157;organic substance metabolic process#GO:0071704;organelle fusion#GO:0048284;mononuclear cell proliferation#GO:0032943;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;regulation of body fluid levels#GO:0050878;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;neuron projection development#GO:0031175;response to stress#GO:0006950;response to wounding#GO:0009611;leukocyte activation involved in immune response#GO:0002366;exocytosis#GO:0006887;neuron development#GO:0048666;immune response-activating cell surface receptor signaling pathway#GO:0002429;cellular response to stress#GO:0033554;vesicle fusion#GO:0006906;macromolecule modification#GO:0043412;animal organ development#GO:0048513;transport#GO:0006810;developmental process#GO:0032502;wound healing#GO:0042060;peptidyl-amino acid modification#GO:0018193;positive regulation of response to stimulus#GO:0048584;regulation of transport#GO:0051049;platelet aggregation#GO:0070527;protein autophosphorylation#GO:0046777;hemopoiesis#GO:0030097;negative regulation of cell population proliferation#GO:0008285;phosphorylation#GO:0016310;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of response to external stimulus#GO:0032101;regulation of apoptotic process#GO:0042981;lymphocyte activation#GO:0046649;leukocyte mediated immunity#GO:0002443;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;coagulation#GO:0050817;cell development#GO:0048468;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of leukocyte activation#GO:0002694;peptidyl-tyrosine modification#GO:0018212;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;negative regulation of immune system process#GO:0002683;establishment of localization in cell#GO:0051649;regulation of leukocyte proliferation#GO:0070663;generation of neurons#GO:0048699 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 Parkinson disease#P00049>Src kinase#P01230;B cell activation#P00010>Blk#P00390 HUMAN|HGNC=28745|UniProtKB=Q86UD7 Q86UD7 TBC1D26 PTHR22957:SF598 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 26-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=28554|UniProtKB=Q6V702 Q6V702 CFAP299 PTHR33588:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299 structural protein#PC00211 HUMAN|HGNC=1776|UniProtKB=Q13319 Q13319 CDK5R2 PTHR23401:SF3 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 2 kinase activator#PC00138 HUMAN|HGNC=26629|UniProtKB=Q86TJ5 Q86TJ5 ZNF554 PTHR24381:SF56 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 554 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21357|UniProtKB=Q5T0W9 Q5T0W9 FAM83B PTHR16181:SF23 UNCHARACTERIZED PROTEIN FAM83B regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=17174|UniProtKB=Q9UJ70 Q9UJ70 NAGK PTHR12862:SF0 BADF TYPE ATPASE DOMAIN-CONTAINING PROTEIN N-ACETYL-D-GLUCOSAMINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 HUMAN|HGNC=26501|UniProtKB=B6SEH8 B6SEH8 ERVV-1 PTHR10424:SF74 VIRAL ENVELOPE PROTEIN ENDOGENOUS RETROVIRUS GROUP V MEMBER 1 ENV POLYPROTEIN-RELATED viral or transposable element protein#PC00237 HUMAN|HGNC=9236|UniProtKB=P37231 P37231 PPARG PTHR24082:SF488 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;negative regulation of inflammatory response#GO:0050728;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;regulation of defense response#GO:0031347;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of lipid metabolic process#GO:0019216;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;inflammatory response#GO:0006954;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of inflammatory response#GO:0050727;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 CCKR signaling map#P06959>PPARgamma#P07060;Gonadotropin-releasing hormone receptor pathway#P06664>PPARgamma#P06721;Gonadotropin-releasing hormone receptor pathway#P06664>PPARalpha/gamma#P06744 HUMAN|HGNC=12796|UniProtKB=P19544 P19544 WT1 PTHR23235:SF49 KRUEPPEL-LIKE TRANSCRIPTION FACTOR WILMS TUMOR PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;negative regulation of programmed cell death#GO:0043069;cellular nitrogen compound biosynthetic process#GO:0044271;apoptotic process#GO:0006915;cell death#GO:0008219;negative regulation of cell population proliferation#GO:0008285;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;programmed cell death#GO:0012501;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of cell death#GO:0060548;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of cell death#GO:0010941;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13887|UniProtKB=Q9H221 Q9H221 ABCG8 PTHR48041:SF71 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 8 biological regulation#GO:0065007;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;regulation of biological quality#GO:0065008;cholesterol homeostasis#GO:0042632 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=18940|UniProtKB=Q3LI72 Q3LI72 KRTAP19-5 PTHR38140:SF4 KERATIN-ASSOCIATED PROTEIN 19-3-RELATED KERATIN-ASSOCIATED PROTEIN 19-5 HUMAN|HGNC=25715|UniProtKB=Q5JXC2 Q5JXC2 MIIP PTHR34831:SF1 MIGRATION AND INVASION-INHIBITORY PROTEIN MIGRATION AND INVASION-INHIBITORY PROTEIN HUMAN|HGNC=32016|UniProtKB=P0C7M7 P0C7M7 ACSM4 PTHR43605:SF8 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM4, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 HUMAN|HGNC=7551|UniProtKB=Q14896 Q14896 MYBPC3 PTHR13817:SF20 TITIN MYOSIN-BINDING PROTEIN C, CARDIAC-TYPE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488 HUMAN|HGNC=8601|UniProtKB=Q06141 Q06141 REG3A PTHR22803:SF123 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED REGENERATING ISLET-DERIVED PROTEIN 3-ALPHA carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 response to organic substance#GO:0010033;response to external biotic stimulus#GO:0043207;response to oxygen-containing compound#GO:1901700;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;response to peptide hormone#GO:0043434;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;positive regulation of cell population proliferation#GO:0008284;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to organonitrogen compound#GO:0010243;cell population proliferation#GO:0008283;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607;response to chemical#GO:0042221;response to peptide#GO:1901652;antimicrobial humoral response#GO:0019730;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=21306|UniProtKB=Q9BT30 Q9BT30 ALKBH7 PTHR21052:SF0 SPERMATOGENESIS ASSOCIATED 11-RELATED ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 7, MITOCHONDRIAL HUMAN|HGNC=18036|UniProtKB=Q96A84 Q96A84 EMID1 PTHR15427:SF23 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMI DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=29434|UniProtKB=Q5TC82 Q5TC82 RC3H1 PTHR13139:SF6 RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN ROQUIN-1 HUMAN|HGNC=6656|UniProtKB=Q9UIQ6 Q9UIQ6 LNPEP PTHR11533:SF42 PROTEASE M1 ZINC METALLOPROTEASE LEUCYL-CYSTINYL AMINOPEPTIDASE cation binding#GO:0043169;metallopeptidase activity#GO:0008237;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;peptide binding#GO:0042277;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;peptidase activity#GO:0008233;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=2439|UniProtKB=Q99062 Q99062 CSF3R PTHR23036:SF103 CYTOKINE RECEPTOR GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=25484|UniProtKB=Q2KJY2 Q2KJY2 KIF26B PTHR24115:SF363 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF26B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=28106|UniProtKB=Q5BJF2 Q5BJF2 TMEM97 PTHR31204:SF1 SIGMA INTRACELLULAR RECEPTOR 2 SIGMA INTRACELLULAR RECEPTOR 2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=328|UniProtKB=O95994 O95994 AGR2 PTHR15337:SF1 ANTERIOR GRADIENT PROTEIN-RELATED ANTERIOR GRADIENT PROTEIN 2 HOMOLOG regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 reductase#PC00198 HUMAN|HGNC=22135|UniProtKB=Q8IZ16 Q8IZ16 C7orf61 PTHR39221:SF1 CHROMOSOME 7 OPEN READING FRAME 61 CHROMOSOME 7 OPEN READING FRAME 61 HUMAN|HGNC=15134|UniProtKB=Q8NGQ4 Q8NGQ4 OR10Q1 PTHR26452:SF253 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10Q1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=18601|UniProtKB=Q9BZR6 Q9BZR6 RTN4R PTHR24369:SF174 ANTIGEN BSP, PUTATIVE-RELATED RETICULON-4 RECEPTOR HUMAN|HGNC=20197|UniProtKB=Q96A29 Q96A29 SLC35C1 PTHR11132:SF255 SOLUTE CARRIER FAMILY 35 GDP-FUCOSE TRANSPORTER 1 secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=630|UniProtKB=Q13796 Q13796 SHROOM2 PTHR15012:SF8 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cortical cytoskeleton#GO:0030863;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;apical junction complex#GO:0043296 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=24450|UniProtKB=Q8WXF8 Q8WXF8 DEDD2 PTHR15205:SF1 DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN DNA-BINDING DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN 2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;cell death#GO:0008219;biological regulation#GO:0065007;signaling#GO:0023052 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=13262|UniProtKB=Q5VWM6 Q5VWM6 PRAMEF13 PTHR14224:SF81 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 1-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=15470|UniProtKB=O75937 O75937 DNAJC8 PTHR15606:SF7 DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 8 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=15937|UniProtKB=O00762 O00762 UBE2C PTHR24068:SF360 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 C ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;protein catabolic process#GO:0030163;regulation of cellular component organization#GO:0051128;chromosome segregation#GO:0007059;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of mitotic sister chromatid segregation#GO:0033047;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;mitotic cell cycle process#GO:1903047;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;metaphase/anaphase transition of cell cycle#GO:0044784;cellular protein catabolic process#GO:0044257;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of mitotic cell cycle#GO:0007346 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=25947|UniProtKB=Q6TFL4 Q6TFL4 KLHL24 PTHR24412:SF215 KELCH PROTEIN KELCH-LIKE PROTEIN 24 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11769|UniProtKB=P10600 P10600 TGFB3 PTHR11848:SF34 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-3 PROPROTEIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|Gene=HSPC297|UniProtKB=Q9Y6D0 Q9Y6D0 SELENOK PTHR16875:SF0 SELENOPROTEIN K SELENOPROTEIN K cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;metal ion transport#GO:0030001;divalent inorganic cation homeostasis#GO:0072507;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;cation transport#GO:0006812;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;calcium ion transport#GO:0006816;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;divalent metal ion transport#GO:0070838;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;biological regulation#GO:0065007;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=28977|UniProtKB=P53990 P53990 IST1 PTHR12161:SF56 IST1 FAMILY MEMBER IST1 HOMOLOG localization#GO:0051179;macromolecule localization#GO:0033036;protein localization#GO:0008104 HUMAN|HGNC=6628|UniProtKB=Q15334 Q15334 LLGL1 PTHR10241:SF21 LETHAL 2 GIANT LARVAE PROTEIN LETHAL(2) GIANT LARVAE PROTEIN HOMOLOG 1 GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;myosin binding#GO:0017022;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;syntaxin binding#GO:0019905;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;SNARE binding#GO:0000149 cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;protein secretion#GO:0009306;regulation of localization#GO:0032879;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of secretion#GO:0051046;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;regulation of protein localization#GO:0032880;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;regulation of protein secretion#GO:0050708;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;regulation of establishment of protein localization#GO:0070201;export from cell#GO:0140352;regulation of peptide transport#GO:0090087;establishment or maintenance of cell polarity#GO:0007163;vesicle fusion#GO:0006906;signal transduction#GO:0007165;macromolecule localization#GO:0033036;regulation of signaling#GO:0023051;establishment of spindle orientation#GO:0051294;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;peptide secretion#GO:0002790;regulation of Notch signaling pathway#GO:0008593;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;vesicle organization#GO:0016050;regulation of protein transport#GO:0051223;signaling#GO:0023052;spindle localization#GO:0051653;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;localization#GO:0051179;response to stimulus#GO:0050896;membrane fusion#GO:0061025;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;actin cytoskeleton organization#GO:0030036;cortical actin cytoskeleton organization#GO:0030866;Notch signaling pathway#GO:0007219 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=30603|UniProtKB=Q3KNW5 Q3KNW5 SLC10A6 PTHR10361:SF55 SODIUM-BILE ACID COTRANSPORTER SOLUTE CARRIER FAMILY 10 MEMBER 6 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068 HUMAN|HGNC=28399|UniProtKB=Q8NEK8 Q8NEK8 TENT5D PTHR12974:SF30 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5D adenylyltransferase activity#GO:0070566;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;negative regulation of cellular catabolic process#GO:0031330;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265 HUMAN|HGNC=11317|UniProtKB=Q04837 Q04837 SSBP1 PTHR10302:SF0 SINGLE-STRANDED DNA-BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN, MITOCHONDRIAL nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of catalytic activity#GO:0043085;regulation of molecular function#GO:0065009;positive regulation of hydrolase activity#GO:0051345 cellular anatomical entity#GO:0110165 DNA metabolism protein#PC00009 HUMAN|HGNC=37443|UniProtKB=P0CJ92 P0CJ92 GOLGA8H PTHR10881:SF62 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8H-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=5466|UniProtKB=P01344 P01344 IGF2 PTHR46886:SF1 INSULIN-LIKE GROWTH FACTOR II INSULIN-LIKE GROWTH FACTOR II growth factor#PC00112 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882 HUMAN|HGNC=382|UniProtKB=O60218 O60218 AKR1B10 PTHR11732:SF278 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B10 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 reductase#PC00198 HUMAN|HGNC=28291|UniProtKB=Q96NB3 Q96NB3 ZNF830 PTHR13278:SF0 UNCHARACTERIZED ZINC FINGER PROTEIN 830 negative regulation of cellular macromolecule biosynthetic process#GO:2000113;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;nuclear DNA replication#GO:0033260;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;mitotic DNA integrity checkpoint#GO:0044774;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;cell cycle G2/M phase transition#GO:0044839;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;mitotic cell cycle phase transition#GO:0044772;negative regulation of DNA replication#GO:0008156;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;mitotic DNA replication checkpoint#GO:0033314;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of biosynthetic process#GO:0009890;negative regulation of cell cycle phase transition#GO:1901988;mitotic DNA damage checkpoint#GO:0044773;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;negative regulation of mitotic cell cycle#GO:0045930;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA replication checkpoint#GO:0000076;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;DNA replication#GO:0006260;regulation of mitotic cell cycle#GO:0007346;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25188|UniProtKB=Q5JUR7 Q5JUR7 TEX30 PTHR13136:SF11 TESTIS DEVELOPMENT PROTEIN PRTD TESTIS-EXPRESSED PROTEIN 30 HUMAN|HGNC=9126|UniProtKB=O75420 O75420 GIGYF1 PTHR14445:SF37 GRB10 INTERACTING GYF PROTEIN GRB10-INTERACTING GYF PROTEIN 1 HUMAN|HGNC=23600|UniProtKB=Q6L8G9 Q6L8G9 KRTAP5-6 PTHR23262:SF226 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-4-RELATED HUMAN|HGNC=25567|UniProtKB=Q9NVI7 Q9NVI7 ATAD3A PTHR23075:SF5 PUTATIVE ATP-ASE ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3A cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5528|UniProtKB=P01861 P01861 IGHG4 PTHR23266:SF354 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 4 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=24549|UniProtKB=Q9Y605 Q9Y605 MRFAP1 PTHR31324:SF1 MORF4 FAMILY-ASSOCIATED PROTEIN 1-RELATED MORF4 FAMILY-ASSOCIATED PROTEIN 1 HUMAN|HGNC=24292|UniProtKB=Q8N6G5 Q8N6G5 CSGALNACT2 PTHR12369:SF20 CHONDROITIN SYNTHASE CHONDROITIN SULFATE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 HUMAN|HGNC=25428|UniProtKB=Q5T5P2 Q5T5P2 KIAA1217 PTHR22741:SF11 P140CAP/SNIP-RELATED SICKLE TAIL PROTEIN HOMOLOG HUMAN|HGNC=4799|UniProtKB=Q16836 Q16836 HADH PTHR43561:SF3 FAMILY NOT NAMED HYDROXYACYL-COENZYME A DEHYDROGENASE, MITOCHONDRIAL HUMAN|HGNC=4686|UniProtKB=O75343 O75343 GUCY1B2 PTHR45655:SF17 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cGMP-mediated signaling#GO:0019934;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 guanylate cyclase#PC00114 Gonadotropin-releasing hormone receptor pathway#P06664>GC#P06726;Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 HUMAN|HGNC=30185|UniProtKB=Q96SW2 Q96SW2 CRBN PTHR14255:SF4 CEREBLON PROTEIN CEREBLON protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=28738|UniProtKB=Q5THK1 Q5THK1 PRR14L PTHR14522:SF0 EMO2-RELATED PROTEIN PRR14L HUMAN|HGNC=18985|UniProtKB=Q7Z4W1 Q7Z4W1 DCXR PTHR44252:SF2 D-ERYTHRULOSE REDUCTASE L-XYLULOSE REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;glucose metabolic process#GO:0006006;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 reductase#PC00198 HUMAN|HGNC=6320|UniProtKB=O15066 O15066 KIF3B PTHR24115:SF744 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=17781|UniProtKB=Q969E3 Q969E3 UCN3 PTHR17575:SF1 UROCORTIN-2 AND 3 UROCORTIN-3 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular response to extracellular stimulus#GO:0031668;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to hormone#GO:0009725;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=18779|UniProtKB=Q9UJN7 Q9UJN7 ZNF391 PTHR24381:SF366 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 3-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13386|UniProtKB=Q8TDX7 Q8TDX7 NEK7 PTHR43289:SF2 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED SERINE/THREONINE-PROTEIN KINASE NEK7 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=24781|UniProtKB=Q6ZTR7 Q6ZTR7 CIBAR2 PTHR21223:SF3 UNCHARACTERIZED CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=14759|UniProtKB=Q8NGJ5 Q8NGJ5 OR51L1 PTHR26450:SF37 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51L1 transmembrane signal receptor#PC00197 HUMAN|HGNC=16204|UniProtKB=Q9BQP9 Q9BQP9 BPIFA3 PTHR47736:SF1 BPI FOLD-CONTAINING FAMILY A MEMBER 3 BPI FOLD-CONTAINING FAMILY A MEMBER 3 HUMAN|HGNC=15489|UniProtKB=Q9NQX6 Q9NQX6 ZNF331 PTHR24384:SF209 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 331 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=1911|UniProtKB=Q13112 Q13112 CHAF1B PTHR15271:SF4 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=4888|UniProtKB=Q03591 Q03591 CFHR1 PTHR45785:SF12 COMPLEMENT FACTOR H-RELATED COMPLEMENT FACTOR H-RELATED PROTEIN 1-RELATED HUMAN|HGNC=1774|UniProtKB=Q00535 Q00535 CDK5 PTHR24056:SF46 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT-LIKE KINASE 5 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Nicotine pharmacodynamics pathway#P06587>CDK5#P06597;Axon guidance mediated by semaphorins#P00007>Cdk5#P00336;p53 pathway#P00059>Cdc2#P04634;Dopamine receptor mediated signaling pathway#P05912>CDK5#P05951 HUMAN|HGNC=3649|UniProtKB=Q9UK73 Q9UK73 FEM1B PTHR24173:SF78 FAMILY NOT NAMED PROTEIN FEM-1 HOMOLOG B HUMAN|HGNC=10385|UniProtKB=P25398 P25398 RPS12 PTHR11843:SF19 40S RIBOSOMAL PROTEIN S12 40S RIBOSOMAL PROTEIN S12 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=28550|UniProtKB=Q6ZUK4 Q6ZUK4 TMEM26 PTHR22168:SF3 TMEM26 PROTEIN TRANSMEMBRANE PROTEIN 26 HUMAN|HGNC=29361|UniProtKB=Q9C0D9 Q9C0D9 SELENOI PTHR10414:SF47 ETHANOLAMINEPHOSPHOTRANSFERASE ETHANOLAMINEPHOSPHOTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=15301|UniProtKB=O95222 O95222 OR6A2 PTHR26453:SF234 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6A2 transmembrane signal receptor#PC00197 HUMAN|HGNC=7905|UniProtKB=O15259 O15259 NPHP1 PTHR15176:SF1 NEPHROCYSTIN NEPHROCYSTIN-1 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;anatomical structure morphogenesis#GO:0009653;cellular protein localization#GO:0034613;epithelium development#GO:0060429;anatomical structure development#GO:0048856;developmental process#GO:0032502;tissue morphogenesis#GO:0048729;establishment of planar polarity#GO:0001736;morphogenesis of an epithelium#GO:0002009;cellular process#GO:0009987;tissue development#GO:0009888;protein localization#GO:0008104 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 cell junction protein#PC00070 HUMAN|HGNC=12875|UniProtKB=Q9NZV7 Q9NZV7 ZIM2 PTHR24381:SF118 ZINC FINGER PROTEIN ZINC FINGER IMPRINTED 2-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=27898|UniProtKB=Q3KNT9 Q3KNT9 TMEM95 PTHR38808:SF1 TRANSMEMBRANE PROTEIN 95 TRANSMEMBRANE PROTEIN 95 HUMAN|HGNC=24346|UniProtKB=Q96RT6 Q96RT6 CTAGE1 PTHR23158:SF52 MELANOMA INHIBITORY ACTIVITY-RELATED CTAGE FAMILY MEMBER 2 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=39039|UniProtKB=P63136 P63136 ERVK-25 PTHR41694:SF4 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 10 POL PROTEIN-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 viral or transposable element protein#PC00237 HUMAN|HGNC=9782|UniProtKB=P61018 P61018 RAB4B PTHR47979:SF17 DRAB11-RELATED RAS-RELATED PROTEIN RAB-4B regulation of endocytosis#GO:0030100;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;vesicle organization#GO:0016050 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=26970|UniProtKB=Q5RI15 Q5RI15 COX20 PTHR31586:SF2 CYTOCHROME C OXIDASE PROTEIN 20 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidase#PC00175 HUMAN|HGNC=15671|UniProtKB=Q8NI38 Q8NI38 NFKBID PTHR24124:SF7 ANKYRIN REPEAT FAMILY A NF-KAPPA-B INHIBITOR DELTA regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=20667|UniProtKB=Q86VQ6 Q86VQ6 TXNRD3 PTHR48105:SF30 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN REDUCTASE 3 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 biological regulation#GO:0065007;regulation of biological process#GO:0050789;homeostatic process#GO:0042592;cellular process#GO:0009987;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 reductase#PC00198 HUMAN|HGNC=33743|UniProtKB=Q5JRM2 Q5JRM2 CXorf66 PTHR37340:SF1 GENE 7073-RELATED GENE 7073-RELATED HUMAN|HGNC=8574|UniProtKB=P43034 P43034 PAFAH1B1 PTHR44129:SF1 WD REPEAT-CONTAINING PROTEIN POP1 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT ALPHA cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;tubulin binding#GO:0015631;binding#GO:0005488 vesicle transport along microtubule#GO:0047496;establishment or maintenance of cell polarity#GO:0007163;nuclear migration#GO:0007097;cellular localization#GO:0051641;organelle localization#GO:0051640;nuclear division#GO:0000280;transport#GO:0006810;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;regulation of molecular function#GO:0065009;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;regulation of hydrolase activity#GO:0051336;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;vesicle localization#GO:0051648;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;transport along microtubule#GO:0010970;establishment of spindle localization#GO:0051293;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;establishment of mitotic spindle orientation#GO:0000132;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;nucleus localization#GO:0051647;vesicle cytoskeletal trafficking#GO:0099518 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;nuclear envelope#GO:0005635;chromosome, centromeric region#GO:0000775;cytoplasmic microtubule#GO:0005881;vacuole#GO:0005773;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;microtubule#GO:0005874;envelope#GO:0031975;nucleus#GO:0005634;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=24453|UniProtKB=Q9BVC3 Q9BVC3 DSCC1 PTHR13395:SF6 SISTER CHROMATID COHESION PROTEIN DCC1-RELATED SISTER CHROMATID COHESION PROTEIN DCC1 pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;sister chromatid cohesion#GO:0007062;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;regulation of macromolecule biosynthetic process#GO:0010556;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;cellular macromolecule biosynthetic process#GO:0034645;mitotic sister chromatid cohesion#GO:0007064;macromolecule biosynthetic process#GO:0009059;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;intracellular#GO:0005622;chromosome, centromeric region#GO:0000775;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 replication origin binding protein#PC00199 HUMAN|HGNC=24304|UniProtKB=Q9BPX3 Q9BPX3 NCAPG PTHR14418:SF5 CONDENSIN COMPLEX SUBUNIT 3-RELATED CONDENSIN COMPLEX SUBUNIT 3 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic chromosome condensation#GO:0007076;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;condensed chromosome#GO:0000793;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18257|UniProtKB=A6NER0 A6NER0 TBC1D3F PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=16686|UniProtKB=Q7Z7F7 Q7Z7F7 MRPL55 PTHR34095:SF1 39S RIBOSOMAL PROTEIN L55, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L55, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=15353|UniProtKB=Q8NH41 Q8NH41 OR4K15 PTHR48002:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K15 transmembrane signal receptor#PC00197 HUMAN|HGNC=11012|UniProtKB=Q9Y6M5 Q9Y6M5 SLC30A1 PTHR45820:SF1 FI23527P1 ZINC TRANSPORTER 1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;calcium channel regulator activity#GO:0005246;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=4492|UniProtKB=Q9HC97 Q9HC97 GPR35 PTHR24232:SF54 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 35 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=11457|UniProtKB=O75897 O75897 SULT1C4 PTHR11783:SF63 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1C4 transferase#PC00220 HUMAN|HGNC=21958|UniProtKB=A4D1E1 A4D1E1 ZNF804B PTHR17614:SF12 ZINC FINGER-CONTAINING ZINC FINGER PROTEIN 804B HUMAN|HGNC=22009|UniProtKB=Q6ZVC0 Q6ZVC0 NYAP1 PTHR22633:SF2 NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 2-RELATED NEURONAL TYROSINE-PHOSPHORYLATED PHOSPHOINOSITIDE-3-KINASE ADAPTER 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=16657|UniProtKB=Q9BZR8 Q9BZR8 BCL2L14 PTHR14965:SF1 SI:CH73-248E21.1 APOPTOSIS FACILITATOR BCL-2-LIKE PROTEIN 14 HUMAN|HGNC=10901|UniProtKB=Q13309 Q13309 SKP2 PTHR16134:SF32 F-BOX/TPR REPEAT PROTEIN POF3 S-PHASE KINASE-ASSOCIATED PROTEIN 2 HUMAN|HGNC=24182|UniProtKB=O75973 O75973 C1QL1 PTHR22923:SF64 CEREBELLIN-RELATED C1Q-RELATED FACTOR HUMAN|HGNC=29643|UniProtKB=Q9BV36 Q9BV36 MLPH PTHR14555:SF1 MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED MELANOPHILIN cytoskeletal protein binding#GO:0008092;Ras GTPase binding#GO:0017016;myosin binding#GO:0017022;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;actin binding#GO:0003779;Rab GTPase binding#GO:0017137 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;intracellular organelle#GO:0043229 myelin protein#PC00161 HUMAN|HGNC=33115|UniProtKB=Q6ZN11 Q6ZN11 ZNF793 PTHR24377:SF647 IP01015P-RELATED ZINC FINGER PROTEIN 793 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=15129|UniProtKB=Q8NGN4 Q8NGN4 OR10G9 PTHR26453:SF6 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G4-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=13764|UniProtKB=Q969Z4 Q969Z4 RELT PTHR47397:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19L TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19L cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 transmembrane signal receptor#PC00197 HUMAN|HGNC=14288|UniProtKB=Q96CW9 Q96CW9 NTNG2 PTHR10574:SF27 NETRIN/LAMININ-RELATED NETRIN-G2 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;dendrite development#GO:0016358;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;motor neuron axon guidance#GO:0008045;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 HUMAN|HGNC=2634|UniProtKB=P51589 P51589 CYP2J2 PTHR24300:SF177 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2J2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid derivative metabolic process#GO:1901568;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 oxygenase#PC00177 HUMAN|HGNC=5837|UniProtKB=A0A0A0MT36 A0A0A0MT36 IGKV6D-21 PTHR23267:SF459 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 6-21-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=29485|UniProtKB=Q5VTA0 Q5VTA0 PRAMEF17 PTHR14224:SF2 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 17 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=32034|UniProtKB=Q5TEC3 Q5TEC3 ZNF697 PTHR23226:SF207 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 697 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=18219|UniProtKB=Q9HCU0 Q9HCU0 CD248 PTHR14789:SF4 CHONDROLECTIN VARIANT CHODLFDELTAE. ENDOSIALIN extracellular matrix binding#GO:0050840;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;extracellular matrix#GO:0031012;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=8078|UniProtKB=O95158 O95158 NXPH4 PTHR17103:SF10 NEUREXOPHILIN NEUREXOPHILIN-4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 HUMAN|HGNC=13239|UniProtKB=P58658 P58658 EVA1C PTHR46780:SF4 PROTEIN EVA-1 PROTEIN EVA-1 HOMOLOG C heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=29942|UniProtKB=Q9H1Z9 Q9H1Z9 TSPAN10 PTHR19282:SF294 TETRASPANIN TETRASPANIN-10 protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=5461|UniProtKB=P78318 P78318 IGBP1 PTHR10933:SF12 IMMUNOGLOBULIN-BINDING PROTEIN 1 IMMUNOGLOBULIN-BINDING PROTEIN 1 phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of phosphate metabolic process#GO:0019220;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of dephosphorylation#GO:0035303;cellular metabolic process#GO:0044237;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;phosphorus metabolic process#GO:0006793;regulation of cellular metabolic process#GO:0031323;phosphate-containing compound metabolic process#GO:0006796;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 p53 pathway by glucose deprivation#P04397>alpha4#P04646 HUMAN|HGNC=24558|UniProtKB=Q68BL8 Q68BL8 OLFML2B PTHR23192:SF37 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 2B structural protein#PC00211 HUMAN|HGNC=14663|UniProtKB=A6NGJ6 A6NGJ6 TRIM64 PTHR24103:SF600 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 64-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=23925|UniProtKB=O43310 O43310 CTIF PTHR23254:SF16 EIF4G DOMAIN PROTEIN CBP80/20-DEPENDENT TRANSLATION INITIATION FACTOR nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;regulation of translational initiation#GO:0006446;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;translational initiation#GO:0006413;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=26634|UniProtKB=Q8N239 Q8N239 KLHL34 PTHR45632:SF8 LD33804P KELCH-LIKE PROTEIN 34 HUMAN|HGNC=13363|UniProtKB=Q9H2W2 Q9H2W2 MIXL1 PTHR47656:SF1 HOMEOBOX PROTEIN MIXL HOMEOBOX PROTEIN MIXL1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;ectoderm formation#GO:0001705;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;mesoderm morphogenesis#GO:0048332;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;ectoderm development#GO:0007398;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;mesoderm formation#GO:0001707;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;endoderm formation#GO:0001706;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of RNA metabolic process#GO:0051252;mesoderm development#GO:0007498;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=9556|UniProtKB=O00231 O00231 PSMD11 PTHR10678:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11 cellular component biogenesis#GO:0044085;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein-containing complex assembly#GO:0065003;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;proteasome assembly#GO:0043248;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;cellular protein catabolic process#GO:0044257;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;proteasome complex#GO:0000502 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 HUMAN|HGNC=20818|UniProtKB=Q8TF66 Q8TF66 LRRC15 PTHR24373:SF262 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=21449|UniProtKB=Q86UX2 Q86UX2 ITIH5 PTHR10338:SF62 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H5 protease inhibitor#PC00191 HUMAN|HGNC=53816|UniProtKB=A0A0B4J2D5 A0A0B4J2D5 GATD3B PTHR10224:SF9 ES1 PROTEIN HOMOLOG, MITOCHONDRIAL GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 3A, MITOCHONDRIAL-RELATED cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=21304|UniProtKB=Q9NX46 Q9NX46 ADPRS PTHR16222:SF24 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSE GLYCOHYDROLASE ARH3 hydrolase#PC00121 HUMAN|HGNC=7984|UniProtKB=O00482 O00482 NR5A2 PTHR24086:SF18 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A MEMBER 2 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=26836|UniProtKB=Q08AI6 Q08AI6 SLC38A11 PTHR22950:SF54 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 amino acid transporter#PC00046 HUMAN|HGNC=25387|UniProtKB=Q8IYT4 Q8IYT4 KATNAL2 PTHR23074:SF78 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 2 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;ATPase activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=24059|UniProtKB=O60235 O60235 TMPRSS11D PTHR24253:SF45 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11D serine protease#PC00203 HUMAN|HGNC=23617|UniProtKB=Q8WV83 Q8WV83 SLC35F5 PTHR23051:SF0 SOLUTE CARRIER FAMILY 35, MEMBER F5 SOLUTE CARRIER FAMILY 35 MEMBER F5 secondary carrier transporter#PC00258 HUMAN|HGNC=29437|UniProtKB=Q9HBJ8 Q9HBJ8 CLTRN PTHR46884:SF1 COLLECTRIN COLLECTRIN HUMAN|HGNC=30079|UniProtKB=Q7Z410 Q7Z410 TMPRSS9 PTHR24253:SF81 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 9 serine protease#PC00203 HUMAN|HGNC=15165|UniProtKB=P0C604 P0C604 OR4A8 PTHR48002:SF161 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4A5-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=28837|UniProtKB=Q8WY98 Q8WY98 TMEM234 PTHR28668:SF1 TRANSMEMBRANE PROTEIN 234 TRANSMEMBRANE PROTEIN 234 HUMAN|HGNC=9874|UniProtKB=Q9UJF2 Q9UJF2 RASAL2 PTHR10194:SF52 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN NGAP GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 HUMAN|HGNC=6766|UniProtKB=Q8WXG6 Q8WXG6 MADD PTHR13008:SF7 MAP-KINASE ACTIVATING DEATH DOMAIN PROTEIN MADD /DENN/AEX-3 C.ELEGANS MAP KINASE-ACTIVATING DEATH DOMAIN PROTEIN Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;Ras protein signal transduction#GO:0007265;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of Ras protein signal transduction#GO:0046578;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;cell death#GO:0008219;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 Apoptosis signaling pathway#P00006>MADD#P00267 HUMAN|HGNC=29029|UniProtKB=O43156 O43156 TTI1 PTHR18460:SF3 TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER TELO2-INTERACTING PROTEIN 1 HOMOLOG regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052;TOR signaling#GO:0031929 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;TORC2 complex#GO:0031932;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=2744|UniProtKB=Q9NR30 Q9NR30 DDX21 PTHR47958:SF109 ATP-DEPENDENT RNA HELICASE DBP3 NUCLEOLAR RNA HELICASE 2 pyrophosphatase activity#GO:0016462;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11813|UniProtKB=Q9UNS1 Q9UNS1 TIMELESS PTHR22940:SF4 TIMEOUT/TIMELESS-2 PROTEIN TIMELESS HOMOLOG heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;negative regulation of DNA replication#GO:0008156;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;DNA-dependent DNA replication#GO:0006261;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;DNA replication checkpoint#GO:0000076;regulation of macromolecule metabolic process#GO:0060255;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;pre-replicative complex#GO:0036387;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;chromatin#GO:0000785;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;MCM complex#GO:0042555;CMG complex#GO:0071162;cellular anatomical entity#GO:0110165;organelle#GO:0043226;replication fork protection complex#GO:0031298;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear pre-replicative complex#GO:0005656;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nuclear replication fork#GO:0043596;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;replication fork#GO:0005657 HUMAN|HGNC=15078|UniProtKB=Q8NGB8 Q8NGB8 OR4F15 PTHR48002:SF94 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4F15 transmembrane signal receptor#PC00197 HUMAN|HGNC=24254|UniProtKB=Q96CN7 Q96CN7 ISOC1 PTHR14119:SF17 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 HUMAN|HGNC=5421|UniProtKB=P05015 P05015 IFNA16 PTHR11691:SF71 TYPE I INTERFERON INTERFERON ALPHA-16 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=27995|UniProtKB=Q5TYX0 Q5TYX0 PRAMEF5 PTHR14224:SF100 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 11-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=14450|UniProtKB=Q92539 Q92539 LPIN2 PTHR12181:SF11 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN2 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;phosphoric ester hydrolase activity#GO:0042578 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;lipid catabolic process#GO:0016042;lipid biosynthetic process#GO:0008610;acylglycerol metabolic process#GO:0006639;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;neutral lipid metabolic process#GO:0006638;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;triglyceride biosynthetic process#GO:0019432;carboxylic acid catabolic process#GO:0046395;positive regulation of biological process#GO:0048518;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nucleobase-containing compound biosynthetic process#GO:0034654;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;lipid metabolic process#GO:0006629;response to insulin#GO:0032868;positive regulation of RNA biosynthetic process#GO:1902680;response to peptide hormone#GO:0043434;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;glycerolipid metabolic process#GO:0046486;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;triglyceride metabolic process#GO:0006641;cellular response to chemical stimulus#GO:0070887;glycerolipid biosynthetic process#GO:0045017;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;fatty acid catabolic process#GO:0009062;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=3149|UniProtKB=Q13011 Q13011 ECH1 PTHR43149:SF1 ENOYL-COA HYDRATASE DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL hydratase#PC00120 HUMAN|HGNC=27281|UniProtKB=Q8IY45 Q8IY45 AMN1 PTHR13318:SF162 UNCHARACTERIZED PROTEIN AMN1 HOMOLOG macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=21022|UniProtKB=Q5JTZ9 Q5JTZ9 AARS2 PTHR11777:SF8 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, MITOCHONDRIAL amino acid binding#GO:0016597;hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;ligase activity#GO:0016874;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;organic acid binding#GO:0043177;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;cellular amide metabolic process#GO:0043603;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=28180|UniProtKB=Q9BRR3 Q9BRR3 PGAP4 PTHR31410:SF1 TRANSMEMBRANE PROTEIN 246 POST-GPI ATTACHMENT TO PROTEINS FACTOR 4 HUMAN|HGNC=4292|UniProtKB=Q14409 Q14409 GK3P PTHR10196:SF56 SUGAR KINASE GLYCEROL KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;triglyceride metabolic process#GO:0006641;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;cellular carbohydrate metabolic process#GO:0044262;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 carbohydrate kinase#PC00065 HUMAN|HGNC=26275|UniProtKB=Q6PEZ8 Q6PEZ8 PODNL1 PTHR45712:SF5 AGAP008170-PA PODOCAN-LIKE PROTEIN 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=11524|UniProtKB=Q9Y6A5 Q9Y6A5 TACC3 PTHR13924:SF4 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 3 head development#GO:0060322;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;brain development#GO:0007420;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;cell population proliferation#GO:0008283;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;forebrain development#GO:0030900;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;central nervous system development#GO:0007417 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=1054|UniProtKB=Q9NQY0 Q9NQY0 BIN3 PTHR47174:SF3 BRIDGING INTEGRATOR 3 BRIDGING INTEGRATOR 3 HUMAN|Ensembl=ENSG00000284912|UniProtKB=A0A2R8YE69 A0A2R8YE69 ENSG00000284912 PTHR23158:SF57 MELANOMA INHIBITORY ACTIVITY-RELATED CTAGE FAMILY MEMBER 15-RELATED endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=28559|UniProtKB=Q5VVX9 Q5VVX9 UBE2U PTHR24067:SF252 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 U ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;histone ubiquitination#GO:0016574;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;covalent chromatin modification#GO:0016569;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular protein catabolic process#GO:0044257;chromatin organization#GO:0006325;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=15484|UniProtKB=O75971 O75971 SNAPC5 PTHR15333:SF2 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 5 HUMAN|HGNC=29348|UniProtKB=Q9C0I4 Q9C0I4 THSD7B PTHR11311:SF7 SPONDIN THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 7B cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actin cytoskeleton reorganization#GO:0031532;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=6773|UniProtKB=O15105 O15105 SMAD7 PTHR13703:SF44 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 7 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;ubiquitin protein ligase binding#GO:0031625;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;nucleobase-containing compound metabolic process#GO:0006139;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;response to BMP#GO:0071772;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;BMP signaling pathway#GO:0030509;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;response to growth factor#GO:0070848;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to growth factor stimulus#GO:0071363;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 TGF-beta signaling pathway#P00052>I-SMAD#G01548;TGF-beta signaling pathway#P00052>I-Smads#P01289 HUMAN|HGNC=66|UniProtKB=Q9UBJ2 Q9UBJ2 ABCD2 PTHR11384:SF24 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 2 transporter activity#GO:0005215;lipid transporter activity#GO:0005319 lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;cellular localization#GO:0051641;macromolecule localization#GO:0033036;organic acid transport#GO:0015849;transport#GO:0006810;very long-chain fatty acid metabolic process#GO:0000038;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;lipid transport#GO:0006869;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;anion transport#GO:0006820;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;lipid oxidation#GO:0034440;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ion transmembrane transport#GO:0034220;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;organic acid transmembrane transport#GO:1903825;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;peroxisome organization#GO:0007031;long-chain fatty acid transport#GO:0015909;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;microbody membrane#GO:0031903;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=13251|UniProtKB=Q9UJ99 Q9UJ99 CDH22 PTHR24027:SF311 CADHERIN-23 CADHERIN-22 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=4820|UniProtKB=O00219 O00219 HAS3 PTHR22913:SF6 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 3 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;extracellular matrix organization#GO:0030198;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;carbohydrate biosynthetic process#GO:0016051;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;polysaccharide metabolic process#GO:0005976;extracellular structure organization#GO:0043062;cellular carbohydrate metabolic process#GO:0044262;glycosaminoglycan biosynthetic process#GO:0006024;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;cellular polysaccharide biosynthetic process#GO:0033692;cellular polysaccharide metabolic process#GO:0044264;small molecule metabolic process#GO:0044281 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=11203|UniProtKB=P57073 P57073 SOX8 PTHR45803:SF2 SOX100B TRANSCRIPTION FACTOR SOX-8 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;mesenchymal cell differentiation#GO:0048762;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;mesenchyme development#GO:0060485;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;neural crest cell development#GO:0014032;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;stem cell differentiation#GO:0048863;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=13469|UniProtKB=O75509 O75509 TNFRSF21 PTHR46921:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 21 neuron apoptotic process#GO:0051402;regulation of cell-cell adhesion#GO:0022407;system process#GO:0003008;B cell proliferation#GO:0042100;neuron death#GO:0070997;cell population proliferation#GO:0008283;nervous system development#GO:0007399;regulation of T cell activation#GO:0050863;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;apoptotic process#GO:0006915;B cell activation#GO:0042113;leukocyte activation#GO:0045321;mononuclear cell proliferation#GO:0032943;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;negative regulation of T cell activation#GO:0050868;programmed cell death#GO:0012501;cell adhesion#GO:0007155;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;cell activation#GO:0001775;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;myelination#GO:0042552;negative regulation of biological process#GO:0048519;negative regulation of cell-cell adhesion#GO:0022408;humoral immune response#GO:0006959;biological adhesion#GO:0022610;developmental process#GO:0032502;regulation of system process#GO:0044057;regulation of multicellular organismal development#GO:2000026;leukocyte cell-cell adhesion#GO:0007159;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;T cell proliferation#GO:0042098;adaptive immune response#GO:0002250;cell death#GO:0008219;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;negative regulation of cellular process#GO:0048523;regulation of cell population proliferation#GO:0042127;lymphocyte activation#GO:0046649;immune response#GO:0006955;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;nervous system process#GO:0050877;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;regulation of T cell proliferation#GO:0042129;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;regulation of B cell proliferation#GO:0030888 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=20081|UniProtKB=Q8WX77 Q8WX77 IGFBPL1 PTHR14186:SF16 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-LIKE 1 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=4598|UniProtKB=O15303 O15303 GRM6 PTHR24060:SF24 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 6 adenylate cyclase activity#GO:0004016;amino acid binding#GO:0016597;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;carboxylic acid binding#GO:0031406;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;glutamate binding#GO:0016595 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=24351|UniProtKB=Q9P1Y6 Q9P1Y6 PHRF1 PTHR12618:SF20 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=16213|UniProtKB=B1AKI9 B1AKI9 ISM1 PTHR10239:SF30 ISTHMIN-2 ISTHMIN-1 negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;system development#GO:0048731;negative regulation of multicellular organismal process#GO:0051241;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;regulation of developmental process#GO:0050793;tube morphogenesis#GO:0035239;regulation of vasculature development#GO:1901342;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;vasculature development#GO:0001944;multicellular organismal process#GO:0032501 HUMAN|HGNC=10805|UniProtKB=Q16586 Q16586 SGCA PTHR10132:SF16 ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER ALPHA-SARCOGLYCAN membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 cadherin#PC00057 HUMAN|HGNC=1105|UniProtKB=Q58F21 Q58F21 BRDT PTHR22880:SF175 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN TESTIS-SPECIFIC PROTEIN HUMAN|HGNC=24490|UniProtKB=Q96DR7 Q96DR7 ARHGEF26 PTHR12845:SF4 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 26 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=735|UniProtKB=Q13510 Q13510 ASAH1 PTHR28583:SF1 ACID AMIDASE ACID CERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cysteine protease#PC00081 HUMAN|HGNC=18449|UniProtKB=P28838 P28838 LAP3 PTHR11963:SF39 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE metalloprotease#PC00153 HUMAN|HGNC=28369|UniProtKB=Q86W42 Q86W42 THOC6 PTHR44411:SF1 THO COMPLEX SUBUNIT 6 HOMOLOG THO COMPLEX SUBUNIT 6 HOMOLOG HUMAN|HGNC=4920|UniProtKB=P15822 P15822 HIVEP1 PTHR45944:SF3 SCHNURRI, ISOFORM F ZINC FINGER PROTEIN 40 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28906|UniProtKB=Q9NQR9 Q9NQR9 G6PC2 PTHR12591:SF1 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;glucose 6-phosphate metabolic process#GO:0051156;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 HUMAN|HGNC=6160|UniProtKB=P18084 P18084 ITGB5 PTHR10082:SF26 INTEGRIN BETA SUBUNIT INTEGRIN BETA-5 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;biological adhesion#GO:0022610;localization of cell#GO:0051674;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052 membrane protein complex#GO:0098796;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;focal adhesion#GO:0005925;integral component of plasma membrane#GO:0005887;cell-substrate junction#GO:0030055;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 HUMAN|HGNC=14451|UniProtKB=Q9BQK8 Q9BQK8 LPIN3 PTHR12181:SF62 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN3 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;phosphoric ester hydrolase activity#GO:0042578 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;lipid catabolic process#GO:0016042;lipid biosynthetic process#GO:0008610;acylglycerol metabolic process#GO:0006639;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;neutral lipid metabolic process#GO:0006638;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;triglyceride biosynthetic process#GO:0019432;carboxylic acid catabolic process#GO:0046395;positive regulation of biological process#GO:0048518;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nucleobase-containing compound biosynthetic process#GO:0034654;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;lipid metabolic process#GO:0006629;response to insulin#GO:0032868;positive regulation of RNA biosynthetic process#GO:1902680;response to peptide hormone#GO:0043434;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;glycerolipid metabolic process#GO:0046486;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;triglyceride metabolic process#GO:0006641;cellular response to chemical stimulus#GO:0070887;glycerolipid biosynthetic process#GO:0045017;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;fatty acid catabolic process#GO:0009062;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=35245|UniProtKB=A1L190 A1L190 SYCE3 PTHR36686:SF1 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 3 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 3 HUMAN|HGNC=23465|UniProtKB=Q5VUJ5 Q5VUJ5 AGAP7P PTHR45819:SF7 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 4-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=23602|UniProtKB=Q6L8G8 Q6L8G8 KRTAP5-7 PTHR23262:SF226 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-4-RELATED HUMAN|HGNC=14826|UniProtKB=Q6IF99 Q6IF99 OR10K2 PTHR26451:SF325 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K2 HUMAN|HGNC=24750|UniProtKB=Q32M78 Q32M78 ZNF699 PTHR24377:SF899 IP01015P-RELATED ZINC FINGER PROTEIN 699 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=21995|UniProtKB=Q8NA54 Q8NA54 IQUB PTHR21074:SF0 UNCHARACTERIZED IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=6584|UniProtKB=P01229 P01229 LHB PTHR11515:SF11 GLYCOPROTEIN HORMONE BETA CHAIN LUTROPIN SUBUNIT BETA receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular#GO:0005622 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>LHbeta#P06751;Gonadotropin-releasing hormone receptor pathway#P06664>5' LHbeta#G06889;Gonadotropin-releasing hormone receptor pathway#P06664>LHbeta#G06688;Gonadotropin-releasing hormone receptor pathway#P06664>3' LHbeta#G06903 HUMAN|HGNC=17644|UniProtKB=Q8TC59 Q8TC59 PIWIL2 PTHR22891:SF111 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PIWI-LIKE PROTEIN 2 translation initiation factor#PC00224 HUMAN|HGNC=1170|UniProtKB=Q9NQ31 Q9NQ31 AKIP1 PTHR14330:SF2 A-KINASE-INTERACTING PROTEIN 1 A-KINASE-INTERACTING PROTEIN 1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=20872|UniProtKB=Q969F1 Q969F1 GTF3C6 PTHR21860:SF2 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 6-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 6 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 HUMAN|HGNC=43624|UniProtKB=A0A1W2PQ64 A0A1W2PQ64 SSU72P5 PTHR20383:SF10 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;mRNA 3'-end processing#GO:0031124;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;mRNA polyadenylation#GO:0006378;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;dephosphorylation#GO:0016311;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 protein phosphatase#PC00195 HUMAN|HGNC=33827|UniProtKB=Q5XLA6 Q5XLA6 CARD17 PTHR47901:SF1 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 17 enzyme binding#GO:0019899;protein binding#GO:0005515;protease binding#GO:0002020;binding#GO:0005488 HUMAN|HGNC=23802|UniProtKB=Q6T310 Q6T310 RASL11A PTHR45704:SF3 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE PROTEIN FAMILY MEMBER 11A HUMAN|HGNC=15875|UniProtKB=Q9NUS5 Q9NUS5 AP5S1 PTHR16120:SF0 AP-5 COMPLEX SUBUNIT SIGMA-1 AP-5 COMPLEX SUBUNIT SIGMA-1 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;membrane coat#GO:0030117;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=18655|UniProtKB=Q9UDX4 Q9UDX4 SEC14L3 PTHR23324:SF62 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 3 HUMAN|HGNC=26232|UniProtKB=Q96AH0 Q96AH0 NABP1 PTHR13356:SF5 OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED SOSS COMPLEX SUBUNIT B2 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint#GO:0000075;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;recombinational repair#GO:0000725;mitotic nuclear division#GO:0140014;response to abiotic stimulus#GO:0009628;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;response to ionizing radiation#GO:0010212;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;cellular metabolic process#GO:0044237;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;nuclear chromosome, telomeric region#GO:0000784;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;chromosomal region#GO:0098687 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=2849|UniProtKB=P23743 P23743 DGKA PTHR11255:SF38 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;neutral lipid metabolic process#GO:0006638;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 kinase#PC00137 p53 pathway#P00059>Cdc2#P04634;p53 pathway feedback loops 2#P04398>cdk2#P04653;p53 pathway#P00059>Cdk2#P04625 HUMAN|HGNC=6188|UniProtKB=P78504 P78504 JAG1 PTHR24044:SF448 NOTCH LIGAND FAMILY MEMBER PROTEIN JAGGED-1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 Notch signaling pathway#P00045>Next#P01103;Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Serrate#P01104 HUMAN|HGNC=8623|UniProtKB=P55771 P55771 PAX9 PTHR45636:SF13 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-9 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=7859|UniProtKB=P48645 P48645 NMU PTHR15390:SF0 NEUROMEDIN-U NEUROMEDIN-U HUMAN|HGNC=19114|UniProtKB=P0DSN6 P0DSN6 TAS2R33 PTHR11394:SF139 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 19-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=3803|UniProtKB=O60548 O60548 FOXD2 PTHR11829:SF373 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=15503|UniProtKB=P59901 P59901 LILRA4 PTHR11738:SF98 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 4 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=6860|UniProtKB=P41279 P41279 MAP3K8 PTHR48016:SF31 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 8 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>TPL2#P01364;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;EGF receptor signaling pathway#P00018>MEKK1-5#P00553 HUMAN|HGNC=4512|UniProtKB=Q9Y653 Q9Y653 ADGRG1 PTHR12011:SF318 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G1 carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;binding#GO:0005488;heparin binding#GO:0008201;molecular transducer activity#GO:0060089;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=474|UniProtKB=P04745 P04745 AMY1A PTHR43447:SF45 ALPHA-AMYLASE ALPHA-AMYLASE 1 amylase#PC00048 HUMAN|HGNC=20185|UniProtKB=Q9NX78 Q9NX78 TMEM260 PTHR16214:SF3 TRANSMEMBRANE PROTEIN 260 TRANSMEMBRANE PROTEIN 260 HUMAN|HGNC=14000|UniProtKB=Q9HAZ2 Q9HAZ2 PRDM16 PTHR24393:SF5 ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM16 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29363|UniProtKB=Q9C0D6 Q9C0D6 FHDC1 PTHR45691:SF1 PROTEIN DIAPHANOUS FH2 DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=14241|UniProtKB=Q9H0K4 Q9H0K4 RSPH6A PTHR13159:SF1 RADIAL SPOKEHEAD-RELATED RADIAL SPOKE HEAD PROTEIN 6 HOMOLOG A vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=15754|UniProtKB=P24844 P24844 MYL9 PTHR23049:SF66 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT POLYPEPTIDE 9 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=6470|UniProtKB=P32004 P32004 L1CAM PTHR45080:SF15 CONTACTIN 5 NEURAL CELL ADHESION MOLECULE L1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;axon#GO:0030424 HUMAN|HGNC=12186|UniProtKB=A0A0B4J2E0 A0A0B4J2E0 TRBV12-4 PTHR23268:SF14 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 12-3-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=10404|UniProtKB=P15880 P15880 RPS2 PTHR13718:SF93 RIBOSOMAL S SUBUNIT 40S RIBOSOMAL PROTEIN S2 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=18157|UniProtKB=Q15750 Q15750 TAB1 PTHR13832:SF533 PROTEIN PHOSPHATASE 2C TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 TGF-beta signaling pathway#P00052>TAB#P01290;p38 MAPK pathway#P05918>TAB1#P06035;Toll receptor signaling pathway#P00054>TAB1#P01365 HUMAN|HGNC=17186|UniProtKB=Q8WXH4 Q8WXH4 ASB11 PTHR24136:SF14 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 11 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222 HUMAN|HGNC=10474|UniProtKB=Q9Y265 Q9Y265 RUVBL1 PTHR11093:SF6 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 1 pyrophosphatase activity#GO:0016462;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;ribonucleoprotein complex subunit organization#GO:0071826;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;Ino80 complex#GO:0031011;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 HUMAN|HGNC=25542|UniProtKB=Q2NL82 Q2NL82 TSR1 PTHR12858:SF1 RIBOSOME BIOGENESIS PROTEIN PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG snoRNA binding#GO:0030515;GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;cleavage involved in rRNA processing#GO:0000469;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;endonucleolytic cleavage involved in rRNA processing#GO:0000478;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 preribosome, small subunit precursor#GO:0030688;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991 HUMAN|HGNC=23092|UniProtKB=Q8TCU3 Q8TCU3 SLC7A13 PTHR11785:SF238 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 7 MEMBER 13 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 transporter#PC00227 HUMAN|HGNC=26296|UniProtKB=Q5U5Z8 Q5U5Z8 AGBL2 PTHR12756:SF41 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 2 metalloprotease#PC00153 HUMAN|HGNC=18618|UniProtKB=Q5S007 Q5S007 LRRK2 PTHR45752:SF7 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT SERINE/THREONINE-PROTEIN KINASE 2 protein kinase A binding#GO:0051018;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;GTPase binding#GO:0051020;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transferase activity#GO:0016740;Ras GTPase binding#GO:0017016;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;SNARE binding#GO:0000149 endosomal transport#GO:0016197;cellular component biogenesis#GO:0044085;regulation of dendrite development#GO:0050773;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;macroautophagy#GO:0016236;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;establishment of vesicle localization#GO:0051650;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;establishment of organelle localization#GO:0051656;regulation of multicellular organismal process#GO:0051239;protein localization to endoplasmic reticulum#GO:0070972;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of macroautophagy#GO:0016241;negative regulation of autophagy#GO:0010507;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;multicellular organismal process#GO:0032501;autophagosome organization#GO:1905037;autophagy#GO:0006914;signal transduction#GO:0007165;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;process utilizing autophagic mechanism#GO:0061919;cell differentiation#GO:0030154;system development#GO:0048731;negative regulation of organelle organization#GO:0010639;neuron differentiation#GO:0030182;cellular response to organic cyclic compound#GO:0071407;synaptic vesicle transport#GO:0048489;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;vesicle localization#GO:0051648;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;regulation of membrane potential#GO:0042391;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cytosolic transport#GO:0016482;negative regulation of catabolic process#GO:0009895;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;cellular localization#GO:0051641;cell projection organization#GO:0030030;regulation of catabolic process#GO:0009894;calcium-mediated signaling#GO:0019722;dendrite development#GO:0016358;positive regulation of cellular metabolic process#GO:0031325;endomembrane system organization#GO:0010256;regulation of synapse organization#GO:0050807;plasma membrane bounded cell projection organization#GO:0120036;regulation of vesicle-mediated transport#GO:0060627;vacuole organization#GO:0007033;regulation of biological quality#GO:0065008;dopamine receptor signaling pathway#GO:0007212;anatomical structure morphogenesis#GO:0009653;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;nitrogen compound metabolic process#GO:0006807;dendritic spine organization#GO:0097061;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;Golgi organization#GO:0007030;regulation of dendritic spine development#GO:0060998;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;trans-synaptic signaling#GO:0099537;response to organonitrogen compound#GO:0010243;regulation of cellular localization#GO:0060341;regulation of neuron differentiation#GO:0045664;protein localization#GO:0008104;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;neuron projection development#GO:0031175;synapse organization#GO:0050808;regulation of cell projection organization#GO:0031344;positive regulation of catabolic process#GO:0009896;neuron projection morphogenesis#GO:0048812;autophagosome assembly#GO:0000045;neuron development#GO:0048666;regulation of synapse structure or activity#GO:0050803;positive regulation of autophagy#GO:0010508;intracellular transport#GO:0046907;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of dendrite morphogenesis#GO:0048814;regulation of cell morphogenesis involved in differentiation#GO:0010769;negative regulation of cellular metabolic process#GO:0031324;response to organic cyclic compound#GO:0014070;second-messenger-mediated signaling#GO:0019932;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;transport#GO:0006810;positive regulation of cellular catabolic process#GO:0031331;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;cellular response to nitrogen compound#GO:1901699;regulation of autophagosome assembly#GO:2000785;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to chemical stimulus#GO:0070887;regulation of autophagy#GO:0010506;multicellular organism development#GO:0007275;regulation of cellular catabolic process#GO:0031329;negative regulation of macroautophagy#GO:0016242;dendrite morphogenesis#GO:0048813;regulation of canonical Wnt signaling pathway#GO:0060828;cellular component morphogenesis#GO:0032989;retrograde transport, endosome to Golgi#GO:0042147;organelle assembly#GO:0070925;cell development#GO:0048468;localization#GO:0051179;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of Wnt signaling pathway#GO:0030111;cell junction organization#GO:0034330;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;generation of neurons#GO:0048699 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;vacuole#GO:0005773;organelle membrane#GO:0031090;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;lysosome#GO:0005764;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;plasma membrane region#GO:0098590;cell projection#GO:0042995;membrane region#GO:0098589;membrane microdomain#GO:0098857;envelope#GO:0031975;somatodendritic compartment#GO:0036477;mitochondrial membrane#GO:0031966;intracellular vesicle#GO:0097708;neuronal cell body#GO:0043025;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;mitochondrion#GO:0005739;plasma membrane bounded cell projection#GO:0120025;lytic vacuole#GO:0000323;membrane#GO:0016020;whole membrane#GO:0098805;axon#GO:0030424;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell body#GO:0044297;neuron projection#GO:0043005;perikaryon#GO:0043204;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane raft#GO:0045121;endoplasmic reticulum#GO:0005783;outer membrane#GO:0019867;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18791|UniProtKB=Q9NU63 Q9NU63 ZFP57 PTHR24381:SF277 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 57 HOMOLOG DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4714|UniProtKB=P07305 P07305 H1-0 PTHR11467:SF102 HISTONE H1 HISTONE H1.0 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of chromatin silencing#GO:0031935;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of chromatin silencing#GO:0031936;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of chromatin organization#GO:1902275;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;chromosome condensation#GO:0030261;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of DNA recombination#GO:0000018;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone#PC00118 HUMAN|HGNC=30931|UniProtKB=Q68CK6 Q68CK6 ACSM2B PTHR43605:SF3 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM2B, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 HUMAN|HGNC=25866|UniProtKB=Q9H7Y0 Q9H7Y0 DIPK2B PTHR32073:SF8 GH11358P DIVERGENT PROTEIN KINASE DOMAIN 2B HUMAN|HGNC=8596|UniProtKB=P19021 P19021 PAM PTHR10680:SF14 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 oxygenase#PC00177 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 HUMAN|HGNC=31358|UniProtKB=O60361 O60361 NME2P1 PTHR11349:SF68 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067 kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 HUMAN|HGNC=27314|UniProtKB=A8MSI8 A8MSI8 LYRM9 PTHR47061:SF1 LYR MOTIF-CONTAINING PROTEIN 9 LYR MOTIF-CONTAINING PROTEIN 9 HUMAN|HGNC=13542|UniProtKB=O60312 O60312 ATP10A PTHR24092:SF81 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VA-RELATED pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=11357|UniProtKB=Q92783 Q92783 STAM PTHR45929:SF2 JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE SIGNAL TRANSDUCING ADAPTER MOLECULE 1 protein catabolic process in the vacuole#GO:0007039;endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;multivesicular body sorting pathway#GO:0071985;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular macromolecule localization#GO:0070727;cellular protein catabolic process#GO:0044257;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25823|UniProtKB=Q6N063 Q6N063 OGFOD2 PTHR24014:SF4 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 RNA metabolism protein#PC00031 HUMAN|HGNC=15492|UniProtKB=Q9HCJ1 Q9HCJ1 ANKH PTHR28384:SF1 PROGRESSIVE ANKYLOSIS PROTEIN HOMOLOG PROGRESSIVE ANKYLOSIS PROTEIN HOMOLOG inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ion transmembrane transporter activity#GO:0015075;inorganic anion transmembrane transporter activity#GO:0015103;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=24812|UniProtKB=Q5HYI7 Q5HYI7 MTX3 PTHR12289:SF30 METAXIN RELATED METAXIN-3 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=4087|UniProtKB=P18507 P18507 GABRG2 PTHR18945:SF498 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;cell junction#GO:0030054;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=8215|UniProtKB=Q8NH93 Q8NH93 OR1L3 PTHR48001:SF49 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1L3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=19716|UniProtKB=Q2KHT4 Q2KHT4 GSG1 PTHR10671:SF43 EPITHELIAL MEMBRANE PROTEIN-RELATED GERM CELL-SPECIFIC GENE 1 PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=33154|UniProtKB=P0C7U0 P0C7U0 ELFN1 PTHR24373:SF288 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN PROTEIN ELFN1 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=30367|UniProtKB=Q8WXG8 Q8WXG8 S100Z PTHR11639:SF72 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-Z calmodulin-related#PC00061 HUMAN|HGNC=12390|UniProtKB=Q13630 Q13630 TSTA3 PTHR43238:SF1 GDP-L-FUCOSE SYNTHASE GDP-L-FUCOSE SYNTHASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidoreductase#PC00176 HUMAN|HGNC=12242|UniProtKB=A0A1B0GX51 A0A1B0GX51 TRBV7-8 PTHR23268:SF78 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 7-4-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=2939|UniProtKB=P51530 P51530 DNA2 PTHR10887:SF433 DNA2/NAM7 HELICASE FAMILY DNA REPLICATION ATP-DEPENDENT HELICASE/NUCLEASE DNA2 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;endodeoxyribonuclease activity#GO:0004520;deoxyribonuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;DNA biosynthetic process#GO:0071897;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;replication fork processing#GO:0031297;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;nuclear chromosome, telomeric region#GO:0000784;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome, telomeric region#GO:0000781;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;chromosomal region#GO:0098687 DNA replication#P00017>Hel#P00532 HUMAN|HGNC=33125|UniProtKB=Q6EKJ0 Q6EKJ0 GTF2IRD2B PTHR47831:SF1 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2A-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 general transcription factor#PC00259 HUMAN|HGNC=15193|UniProtKB=Q8NGF3 Q8NGF3 OR51D1 PTHR26450:SF166 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51D1 transmembrane signal receptor#PC00197 HUMAN|HGNC=14478|UniProtKB=Q9BYC9 Q9BYC9 MRPL20 PTHR10986:SF12 39S RIBOSOMAL PROTEIN L20 39S RIBOSOMAL PROTEIN L20, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933 ribosomal protein#PC00202 HUMAN|HGNC=7545|UniProtKB=P10242 P10242 MYB PTHR45614:SF5 MYB PROTEIN-RELATED TRANSCRIPTIONAL ACTIVATOR MYB cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;mitotic nuclear division#GO:0140014;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=37263|UniProtKB=B9EJG8 B9EJG8 TMEM150C PTHR21324:SF7 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED TRANSMEMBRANE PROTEIN 150C process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;biological regulation#GO:0065007;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;cellular catabolic process#GO:0044248;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4648|UniProtKB=Q00403 Q00403 GTF2B PTHR11618:SF13 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION INITIATION FACTOR IIB nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 HUMAN|HGNC=12156|UniProtKB=P01850 P01850 TRBC1 PTHR23266:SF309 IMMUNOGLOBULIN HEAVY CHAIN T CELL RECEPTOR BETA CONSTANT 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=12612|UniProtKB=P54578 P54578 USP14 PTHR43982:SF1 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=16854|UniProtKB=Q9Y4G8 Q9Y4G8 RAPGEF2 PTHR23113:SF217 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 2 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=10000|UniProtKB=P49798 P49798 RGS4 PTHR10845:SF184 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 4 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 HUMAN|HGNC=21204|UniProtKB=Q8WWN9 Q8WWN9 IPCEF1 PTHR12844:SF45 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CNK3/IPCEF1 FUSION PROTEIN-RELATED HUMAN|HGNC=30140|UniProtKB=A7MCY6 A7MCY6 TBKBP1 PTHR14432:SF2 PROSAPIP2 PROTEIN/5-AZACYTIDINE INDUCED GENE 2 TANK-BINDING KINASE 1-BINDING PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;I-kappaB kinase/NF-kappaB signaling#GO:0007249;regulation of DNA-binding transcription factor activity#GO:0051090;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;positive regulation of DNA-binding transcription factor activity#GO:0051091;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=12682|UniProtKB=P49767 P49767 VEGFC PTHR12025:SF3 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR C receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein metabolic process#GO:0051246;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;positive regulation of protein modification process#GO:0031401;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;tube morphogenesis#GO:0035239;epithelial cell proliferation#GO:0050673;sprouting angiogenesis#GO:0002040;positive regulation of epithelial cell proliferation#GO:0050679;cellular protein metabolic process#GO:0044267;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;angiogenesis#GO:0001525;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;taxis#GO:0042330;signal transduction#GO:0007165;response to hypoxia#GO:0001666;positive regulation of angiogenesis#GO:0045766;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of leukocyte migration#GO:0002687;system development#GO:0048731;regulation of chemotaxis#GO:0050920;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;myeloid leukocyte migration#GO:0097529;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;response to oxygen levels#GO:0070482;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;positive regulation of immune system process#GO:0002684;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cell chemotaxis#GO:0060326;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;positive regulation of cellular component movement#GO:0051272;regulation of phosphorus metabolic process#GO:0051174;leukocyte migration#GO:0050900;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;nitrogen compound metabolic process#GO:0006807;vasculature development#GO:0001944;response to abiotic stimulus#GO:0009628;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;response to decreased oxygen levels#GO:0036293;tube development#GO:0035295;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;positive chemotaxis#GO:0050918;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;developmental process#GO:0032502;endothelial cell proliferation#GO:0001935;regulation of angiogenesis#GO:0045765;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;positive regulation of developmental process#GO:0051094;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of leukocyte chemotaxis#GO:0002690;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=18729|UniProtKB=Q96QV6 Q96QV6 H2AC1 PTHR23430:SF137 HISTONE H2A HISTONE H2A TYPE 1-A heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=17125|UniProtKB=Q8NFB2 Q8NFB2 TMEM185A PTHR13568:SF2 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 185A somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;dendrite#GO:0030425;plasma membrane region#GO:0098590;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=24002|UniProtKB=Q9H6S1 Q9H6S1 AZI2 PTHR14432:SF6 PROSAPIP2 PROTEIN/5-AZACYTIDINE INDUCED GENE 2 5-AZACYTIDINE-INDUCED PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;I-kappaB kinase/NF-kappaB signaling#GO:0007249;regulation of DNA-binding transcription factor activity#GO:0051090;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;positive regulation of DNA-binding transcription factor activity#GO:0051091;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=4289|UniProtKB=P32189 P32189 GK PTHR10196:SF92 SUGAR KINASE GLYCEROL KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;triglyceride metabolic process#GO:0006641;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;cellular carbohydrate metabolic process#GO:0044262;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 carbohydrate kinase#PC00065 HUMAN|HGNC=3019|UniProtKB=Q14919 Q14919 DRAP1 PTHR10252:SF5 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DR1-ASSOCIATED COREPRESSOR cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=24311|UniProtKB=Q6XD76 Q6XD76 ASCL4 PTHR13935:SF51 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=6458|UniProtKB=Q14533 Q14533 KRT81 PTHR45616:SF52 FAMILY NOT NAMED KERATIN, TYPE II CUTICULAR HB1 HUMAN|HGNC=6522|UniProtKB=P04180 P04180 LCAT PTHR11440:SF18 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED PHOSPHATIDYLCHOLINE-STEROL ACYLTRANSFERASE transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;carboxylic ester hydrolase activity#GO:0052689;transferase activity, transferring acyl groups#GO:0016746;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;O-acyltransferase activity#GO:0008374;triglyceride lipase activity#GO:0004806 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 acyltransferase#PC00042 HUMAN|HGNC=9853|UniProtKB=O15397 O15397 IPO8 PTHR10997:SF26 IMPORTIN-7, 8, 11 IMPORTIN-8 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=5358|UniProtKB=Q02556 Q02556 IRF8 PTHR11949:SF7 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 8 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=21691|UniProtKB=P86791 P86791 CCZ1 PTHR13056:SF0 UNCHARACTERIZED VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=477|UniProtKB=P04746 P04746 AMY2A PTHR43447:SF27 ALPHA-AMYLASE ALPHA-AMYLASE 2B-RELATED amylase#PC00048 HUMAN|HGNC=18047|UniProtKB=Q9HB03 Q9HB03 ELOVL3 PTHR11157:SF68 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 3 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=23496|UniProtKB=Q7Z2D5 Q7Z2D5 PLPPR4 PTHR10165:SF13 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;lipid modification#GO:0030258;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;phospholipid dephosphorylation#GO:0046839;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;primary metabolic process#GO:0044238;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;dephosphorylation#GO:0016311;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;cellular lipid metabolic process#GO:0044255 phosphatase#PC00181 HUMAN|HGNC=18116|UniProtKB=Q07666 Q07666 KHDRBS1 PTHR11208:SF30 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 1 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA splicing factor#PC00148 HUMAN|HGNC=30324|UniProtKB=Q969G6 Q969G6 RFK PTHR22749:SF13 RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE RIBOFLAVIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 Flavin biosynthesis#P02741>Riboflavin kinase#P02934;Flavin biosynthesis#P02741>FAD synthetase#P02936 HUMAN|HGNC=23243|UniProtKB=Q9NQR7 Q9NQR7 CCDC177 PTHR33663:SF1 FAMILY NOT NAMED COILED-COIL DOMAIN-CONTAINING PROTEIN 177 HUMAN|HGNC=29458|UniProtKB=Q8MH63 Q8MH63 SLC7A5P1 PTHR11785:SF315 AMINO ACID TRANSPORTER L-TYPE AMINO ACID TRANSPORTER 1-LIKE PROTEIN IMAA-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 transporter#PC00227 HUMAN|HGNC=20156|UniProtKB=Q96JJ6 Q96JJ6 JPH4 PTHR23085:SF14 GH28348P JUNCTOPHILIN-4 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of trans-synaptic signaling#GO:0099177;signaling#GO:0023052;cell-cell signaling#GO:0007267 intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=23676|UniProtKB=Q5T1J5 Q5T1J5 CHCHD2P9 PTHR13523:SF3 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 2-RELATED sequence-specific DNA binding#GO:0043565;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;mitochondrion organization#GO:0007005;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14297|UniProtKB=Q5W111 Q5W111 SPRYD7 PTHR20951:SF2 C13ORF1 PROTEIN-RELATED SPRY DOMAIN-CONTAINING PROTEIN 7 HUMAN|HGNC=32698|UniProtKB=Q1HG44 Q1HG44 DUOXA2 PTHR31158:SF2 DUAL OXIDASE 2 DUAL OXIDASE MATURATION FACTOR 2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxidase#PC00175 HUMAN|HGNC=26353|UniProtKB=Q86VV4 Q86VV4 RANBP3L PTHR23138:SF88 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3-LIKE GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;nuclear transport#GO:0051169 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=21708|UniProtKB=Q9BSQ5 Q9BSQ5 CCM2 PTHR21642:SF4 CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN EGF receptor signaling pathway#P00018>MEKK1-5#P00553 HUMAN|HGNC=25669|UniProtKB=Q9HAH1 Q9HAH1 ZNF556 PTHR24381:SF160 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 556 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3810|UniProtKB=Q12947 Q12947 FOXF2 PTHR46262:SF3 FORKHEAD BOX PROTEIN BINIOU FORKHEAD BOX PROTEIN F2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=40028|UniProtKB=F5GYI3 F5GYI3 UBAP1L PTHR15960:SF3 LD44032P UBIQUITIN-ASSOCIATED PROTEIN 1-LIKE protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 protein catabolic process in the vacuole#GO:0007039;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;localization#GO:0051179;modification-dependent macromolecule catabolic process#GO:0043632;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=7215|UniProtKB=Q99550 Q99550 MPHOSPH9 PTHR14926:SF1 M-PHASE PHOSPHOPROTEIN 9 M-PHASE PHOSPHOPROTEIN 9 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=19767|UniProtKB=Q8WXK1 Q8WXK1 ASB15 PTHR24118:SF81 POTE ANKYRIN DOMAIN ANKYRIN REPEAT AND SOCS BOX PROTEIN 15 membrane traffic protein#PC00150 HUMAN|HGNC=16919|UniProtKB=Q99536 Q99536 VAT1 PTHR44054:SF1 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG Huntington disease#P00029>PIG3#G01535 HUMAN|HGNC=15042|UniProtKB=Q8NGW1 Q8NGW1 OR6B3 PTHR26452:SF222 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6B2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=15424|UniProtKB=A6NFC9 A6NFC9 OR2W5 PTHR26453:SF79 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2W5-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=2592|UniProtKB=P19099 P19099 CYP11B2 PTHR24279:SF1 FAMILY NOT NAMED CYTOCHROME P450 11B2, MITOCHONDRIAL sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;response to peptide hormone#GO:0043434;cholesterol metabolic process#GO:0008203;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular response to nitrogen compound#GO:1901699;steroid metabolic process#GO:0008202;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biological quality#GO:0065008;secondary alcohol metabolic process#GO:1902652;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;hormone biosynthetic process#GO:0042446;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular response to peptide#GO:1901653;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;regulation of hormone levels#GO:0010817;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;steroid biosynthetic process#GO:0006694;small molecule metabolic process#GO:0044281 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=21945|UniProtKB=A8MWY0 A8MWY0 ELAPOR2 PTHR22727:SF3 PROTEIN CBG13728 ENDOSOME/LYSOSOME-ASSOCIATED APOPTOSIS AND AUTOPHAGY REGULATOR FAMILY MEMBER 2 HUMAN|HGNC=3420|UniProtKB=Q12929 Q12929 EPS8 PTHR12287:SF21 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8 Rho guanyl-nucleotide exchange factor activity#GO:0005089;cytoskeletal protein binding#GO:0008092;Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;actin binding#GO:0003779;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cell projection organization#GO:0030030;positive regulation of cell projection organization#GO:0031346;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;regulation of cellular component organization#GO:0051128;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;positive regulation of cellular component biogenesis#GO:0044089;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;Rho protein signal transduction#GO:0007266;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;plasma membrane bounded cell projection assembly#GO:0120031;regulation of Ras protein signal transduction#GO:0046578 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=1353|UniProtKB=P07358 P07358 C8B PTHR45742:SF5 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C8 BETA CHAIN HUMAN|HGNC=8988|UniProtKB=Q13526 Q13526 PIN1 PTHR10657:SF31 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=20360|UniProtKB=Q96NI6 Q96NI6 LRFN5 PTHR45842:SF10 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 5 HUMAN|HGNC=16429|UniProtKB=O43766 O43766 LIAS PTHR10949:SF0 LIPOYL SYNTHASE LIPOYL SYNTHASE, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 Lipoate_biosynthesis#P02750>Lipoate synthase#P03004 HUMAN|HGNC=24711|UniProtKB=Q6ZSS7 Q6ZSS7 MFSD6 PTHR16172:SF2 UNCHARACTERIZED MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=34333|UniProtKB=Q6ZNA1 Q6ZNA1 ZNF836 PTHR24376:SF128 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 836-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28850|UniProtKB=Q8WUA8 Q8WUA8 TSKU PTHR45617:SF14 LEUCINE RICH REPEAT FAMILY PROTEIN TSUKUSHIN HUMAN|HGNC=7720|UniProtKB=P20929 P20929 NEB PTHR11039:SF37 NEBULIN NEBULIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;animal organ development#GO:0048513;developmental process#GO:0032502;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cardiac muscle cell development#GO:0055013;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cardiocyte differentiation#GO:0035051;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;Z disc#GO:0030018;intracellular#GO:0005622;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;I band#GO:0031674 HUMAN|HGNC=29063|UniProtKB=Q5VV63 Q5VV63 ATRNL1 PTHR10574:SF224 NETRIN/LAMININ-RELATED ATTRACTIN-LIKE PROTEIN 1 system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;tissue development#GO:0009888 extracellular matrix protein#PC00102 HUMAN|HGNC=19664|UniProtKB=Q9UK08 Q9UK08 GNG8 PTHR13809:SF19 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-8 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 HUMAN|HGNC=25783|UniProtKB=Q14CX7 Q14CX7 NAA25 PTHR22767:SF3 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;N-acyltransferase activity#GO:0016410 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;N-terminal protein amino acid acetylation#GO:0006474;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 acetyltransferase#PC00038 HUMAN|HGNC=1046|UniProtKB=O14503 O14503 BHLHE40 PTHR10985:SF3 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 40 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;circadian regulation of gene expression#GO:0032922;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=15455|UniProtKB=O43462 O43462 MBTPS2 PTHR13325:SF3 PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=3357|UniProtKB=Q13822 Q13822 ENPP2 PTHR10151:SF21 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 2 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;exonuclease activity#GO:0004527;phosphoric ester hydrolase activity#GO:0042578;carboxylic ester hydrolase activity#GO:0052689;cation binding#GO:0043169;lipase activity#GO:0016298;lysophospholipase activity#GO:0004622;hydrolase activity#GO:0016787;calcium ion binding#GO:0005509;phosphoric diester hydrolase activity#GO:0008081;ion binding#GO:0043167;phospholipase activity#GO:0004620 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=37147|UniProtKB=A6NI03 A6NI03 TRIM64B PTHR24103:SF600 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 64-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=27309|UniProtKB=Q86XF0 Q86XF0 DHFR2 PTHR48069:SF1 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE 2, MITOCHONDRIAL nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;NADP binding#GO:0050661;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;pteridine-containing compound metabolic process#GO:0042558;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;heterocycle biosynthetic process#GO:0018130;amide biosynthetic process#GO:0043604;folic acid-containing compound biosynthetic process#GO:0009396;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 reductase#PC00198 Formyltetrahydroformate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 HUMAN|HGNC=16971|UniProtKB=Q8WU20 Q8WU20 FRS2 PTHR21258:SF40 DOCKING PROTEIN RELATED FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 2 FGF signaling pathway#P00021>FRS2#P00635;Angiogenesis#P00005>FRS-2#P00240 HUMAN|HGNC=28444|UniProtKB=Q69YG0 Q69YG0 TMEM42 PTHR31965:SF1 TRANSMEMBRANE PROTEIN 42 TRANSMEMBRANE PROTEIN 42 HUMAN|HGNC=6761|UniProtKB=Q05195 Q05195 MXD1 PTHR11969:SF18 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=37865|UniProtKB=A0A0U1RQE8 A0A0U1RQE8 GLYATL1B PTHR15298:SF16 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 1B-RELATED transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 oxoacid metabolic process#GO:0043436;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid metabolic process#GO:0006520;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=7151|UniProtKB=Q9BYG8 Q9BYG8 GSDMC PTHR16399:SF21 GASDERMIN GASDERMIN-C phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;defense response#GO:0006952 HUMAN|HGNC=26373|UniProtKB=Q2VWP7 Q2VWP7 PRTG PTHR12231:SF228 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN PROTOGENIN HUMAN|HGNC=357|UniProtKB=O14862 O14862 AIM2 PTHR12200:SF17 INTERFERON-INDUCIBLE PROTEIN AIM2 FAMILY MEMBER INTERFERON-INDUCIBLE PROTEIN AIM2-RELATED nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 response to organic substance#GO:0010033;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cellular process#GO:0009987 DNA-binding transcription factor#PC00218 HUMAN|HGNC=23675|UniProtKB=Q5QJU3 Q5QJU3 ACER2 PTHR46139:SF1 ALKALINE CERAMIDASE ALKALINE CERAMIDASE 2 HUMAN|HGNC=7836|UniProtKB=Q8TAU0 Q8TAU0 NKX2-3 PTHR24340:SF32 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=11541|UniProtKB=Q15545 Q15545 TAF7 PTHR12228:SF6 TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 7 molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110;RNA polymerase II general transcription initiation factor activity#GO:0016251 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;DNA-templated transcription, initiation#GO:0006352;transcription preinitiation complex assembly#GO:0070897;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=6240|UniProtKB=P15382 P15382 KCNE1 PTHR15282:SF10 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1-RELATED cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;protein binding#GO:0005515;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 blood circulation#GO:0008015;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of metal ion transport#GO:0010959;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;action potential#GO:0001508;regulation of localization#GO:0032879;regulation of system process#GO:0044057;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;actin-mediated cell contraction#GO:0070252;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;actin filament-based process#GO:0030029;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;monovalent inorganic cation transport#GO:0015672;regulation of multicellular organismal process#GO:0051239;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of heart contraction#GO:0008016;ion transport#GO:0006811;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;regulation of membrane potential#GO:0042391;negative regulation of transport#GO:0051051;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;export from cell#GO:0140352;heart process#GO:0003015;muscle contraction#GO:0006936;negative regulation of molecular function#GO:0044092 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=26969|UniProtKB=Q7Z3D4 Q7Z3D4 LYSMD3 PTHR20932:SF5 LOC443603 PROTEIN-RELATED AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 3-RELATED endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=41984|UniProtKB=A0A0B4J1W7 A0A0B4J1W7 NPIPA9 PTHR15438:SF14 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER A1-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3601|UniProtKB=P98095 P98095 FBLN2 PTHR24039:SF32 FIBRILLIN-RELATED FIBULIN-2 extracellular matrix structural protein#PC00103 HUMAN|HGNC=6331|UniProtKB=P43628 P43628 KIR2DL3 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=13728|UniProtKB=Q86Y34 Q86Y34 ADGRG3 PTHR12011:SF285 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR G3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=9046|UniProtKB=Q9UM63 Q9UM63 PLAGL1 PTHR24399:SF31 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER PROTEIN PLAGL1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=14472|UniProtKB=Q9BXS9 Q9BXS9 SLC26A6 PTHR11814:SF113 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 6 inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;inorganic anion transmembrane transporter activity#GO:0015103;active ion transmembrane transporter activity#GO:0022853 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=26152|UniProtKB=Q9H6T0 Q9H6T0 ESRP2 PTHR13976:SF30 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED EPITHELIAL SPLICING REGULATORY PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=48628|UniProtKB=A0A1B0GTD5 A0A1B0GTD5 TEX49 PTHR35263:SF1 TESTIS-EXPRESSED PROTEIN 49 TESTIS-EXPRESSED PROTEIN 49 HUMAN|HGNC=16248|UniProtKB=Q9H106 Q9H106 SIRPD PTHR19971:SF25 SIGNAL-REGULATORY PROTEIN BETA SIGNAL-REGULATORY PROTEIN DELTA cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=11071|UniProtKB=P19634 P19634 SLC9A1 PTHR10110:SF59 SODIUM/HYDROGEN EXCHANGER SODIUM/HYDROGEN EXCHANGER 1 secondary carrier transporter#PC00258 HUMAN|HGNC=11122|UniProtKB=Q9UHP9 Q9UHP9 SMPX PTHR17416:SF0 SMALL MUSCULAR PROTEIN SMALL MUSCULAR PROTEIN supramolecular complex#GO:0099080;anchoring junction#GO:0070161;cell junction#GO:0030054;A band#GO:0031672;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;sarcomere#GO:0030017;cell-substrate junction#GO:0030055;myofibril#GO:0030016 HUMAN|HGNC=9224|UniProtKB=Q14863 Q14863 POU6F1 PTHR11636:SF6 POU DOMAIN POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=10862|UniProtKB=Q11201 Q11201 ST3GAL1 PTHR46032:SF6 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 1 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 transferase#PC00220 HUMAN|HGNC=3393|UniProtKB=P29323 P29323 EPHB2 PTHR24416:SF123 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-B RECEPTOR 2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;central nervous system neuron differentiation#GO:0021953;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;central nervous system development#GO:0007417;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 PDGF signaling pathway#P00047>PDGF receptor B#P01156;Angiogenesis#P00005>EphR#P00212 HUMAN|HGNC=1321|UniProtKB=Q9NPL8 Q9NPL8 TIMMDC1 PTHR13002:SF1 C3ORF1 PROTEIN-RELATED COMPLEX I ASSEMBLY FACTOR TIMMDC1, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=10905|UniProtKB=Q14973 Q14973 SLC10A1 PTHR10361:SF40 SODIUM-BILE ACID COTRANSPORTER SODIUM/BILE ACID COTRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068 HUMAN|HGNC=18332|UniProtKB=Q17RP2 Q17RP2 TIGD6 PTHR19303:SF52 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 6 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 HUMAN|HGNC=9047|UniProtKB=Q9UPG8 Q9UPG8 PLAGL2 PTHR24408:SF20 ZINC FINGER PROTEIN ZINC FINGER PROTEIN PLAGL2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1291|UniProtKB=Q9Y3R5 Q9Y3R5 DOP1B PTHR14042:SF23 DOPEY-RELATED PROTEIN DOPEY-2 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=28889|UniProtKB=Q9Y3Q3 Q9Y3Q3 TMED3 PTHR22811:SF60 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 3 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;COPI vesicle coat#GO:0030126;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=23378|UniProtKB=Q5HYC2 Q5HYC2 KIAA2026 PTHR31095:SF3 RIKEN CDNA 9930021J03 GENE BROMO DOMAIN-CONTAINING PROTEIN HUMAN|Ensembl=ENSG00000249156|UniProtKB=A0A1W2PPW3 A0A1W2PPW3 TAF11L12 PTHR13218:SF15 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TAF11-LIKE PROTEIN ENSP00000332601-RELATED transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=49371|UniProtKB=A8MWD9 A8MWD9 SNRPGP15 PTHR10553:SF26 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;SMN complex#GO:0032797;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974;U12-type spliceosomal complex#GO:0005689;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;catalytic complex#GO:1902494;U1 snRNP#GO:0005685;U4 snRNP#GO:0005687;U5 snRNP#GO:0005682;cytoplasmic ribonucleoprotein granule#GO:0036464;SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;spliceosomal tri-snRNP complex#GO:0097526;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 HUMAN|HGNC=18253|UniProtKB=Q9H300 Q9H300 PARL PTHR43731:SF14 RHOMBOID PROTEASE PRESENILINS-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 HUMAN|HGNC=17858|UniProtKB=Q86YR5 Q86YR5 GPSM1 PTHR45954:SF2 LD33695P G-PROTEIN-SIGNALING MODULATOR 1 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>AGS3#P00715;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>AGS3#P00739 HUMAN|HGNC=29683|UniProtKB=Q9H2D1 Q9H2D1 SLC25A32 PTHR45683:SF3 MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED MITOCHONDRIAL FOLATE TRANSPORTER/CARRIER inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;dicarboxylic acid transmembrane transporter activity#GO:0005310;organophosphate ester transmembrane transporter activity#GO:0015605;amide transmembrane transporter activity#GO:0042887;nucleobase-containing compound transmembrane transporter activity#GO:0015932;ion transmembrane transporter activity#GO:0015075;nucleotide transmembrane transporter activity#GO:0015215;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 transporter#PC00227 HUMAN|HGNC=4575|UniProtKB=Q9ULK0 Q9ULK0 GRID1 PTHR18966:SF108 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, DELTA-1 amino acid binding#GO:0016597;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;anion binding#GO:0043168;ion binding#GO:0043167;glutamate binding#GO:0016595;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=16410|UniProtKB=Q96LL9 Q96LL9 DNAJC30 PTHR44873:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL chaperone#PC00072 HUMAN|HGNC=19874|UniProtKB=Q9H0E9 Q9H0E9 BRD8 PTHR15398:SF4 BROMODOMAIN-CONTAINING PROTEIN 8 BROMODOMAIN-CONTAINING PROTEIN 8 peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=7211|UniProtKB=P29372 P29372 MPG PTHR10429:SF0 DNA-3-METHYLADENINE GLYCOSYLASE DNA-3-METHYLADENINE GLYCOSYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA glycosylase#PC00010 HUMAN|HGNC=24954|UniProtKB=Q8WW32 Q8WW32 HMGB4 PTHR48112:SF7 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B4 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;DNA binding, bending#GO:0008301;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=15819|UniProtKB=Q15327 Q15327 ANKRD1 PTHR24126:SF7 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26657|UniProtKB=Q8NA75 Q8NA75 DCAF4L2 PTHR44472:SF4 DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 4-LIKE PROTEIN 2 HUMAN|HGNC=18984|UniProtKB=Q8WYA1 Q8WYA1 ARNTL2 PTHR23042:SF48 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=21305|UniProtKB=Q9Y597 Q9Y597 KCTD3 PTHR15859:SF2 SETA BINDING PROTEIN 1 BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD3 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9817|UniProtKB=Q06609 Q06609 RAD51 PTHR22942:SF39 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER DNA REPAIR PROTEIN RAD51 HOMOLOG 1 DNA metabolism protein#PC00009 HUMAN|HGNC=13853|UniProtKB=Q9BRR0 Q9BRR0 ZKSCAN3 PTHR23226:SF130 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15212|UniProtKB=Q9H346 Q9H346 OR52D1 PTHR26450:SF75 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52D1 transmembrane signal receptor#PC00197 HUMAN|HGNC=30911|UniProtKB=Q9Y4B6 Q9Y4B6 DCAF1 PTHR13129:SF4 VPRBP PROTEIN-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 1 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 HUMAN|Ensembl=ENSG00000248713|UniProtKB=D6RIA3 D6RIA3 C4orf54 PTHR33775:SF4 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED DUF4585 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=28772|UniProtKB=Q9BVC5 Q9BVC5 C2orf49 PTHR28359:SF1 ASHWIN ASHWIN HUMAN|HGNC=20564|UniProtKB=Q9NUK0 Q9NUK0 MBNL3 PTHR12675:SF3 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 3 RNA splicing factor#PC00148 HUMAN|HGNC=7858|UniProtKB=O60551 O60551 NMT2 PTHR11377:SF14 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;protein acylation#GO:0043543;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transferase#PC00220 HUMAN|HGNC=10622|UniProtKB=P55773 P55773 CCL23 PTHR12015:SF157 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 23 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=7036|UniProtKB=Q08431 Q08431 MFGE8 PTHR24543:SF317 MULTICOPPER OXIDASE-RELATED LACTADHERIN oxidoreductase#PC00176 HUMAN|HGNC=18249|UniProtKB=Q719H9 Q719H9 KCTD1 PTHR14499:SF65 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD1 molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=23606|UniProtKB=Q6L8G4 Q6L8G4 KRTAP5-11 PTHR23262:SF134 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-11 HUMAN|HGNC=278|UniProtKB=P35368 P35368 ADRA1B PTHR24248:SF17 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1B ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of lipase activity#GO:0060191;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular cation homeostasis#GO:0030003;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 HUMAN|HGNC=17416|UniProtKB=Q8WXG9 Q8WXG9 ADGRV1 PTHR46682:SF1 ADHESION G-PROTEIN COUPLED RECEPTOR V1 ADHESION G-PROTEIN COUPLED RECEPTOR V1 G-protein coupled receptor#PC00021 HUMAN|HGNC=9226|UniProtKB=Q15181 Q15181 PPA1 PTHR10286:SF47 INORGANIC PYROPHOSPHATASE INORGANIC PYROPHOSPHATASE pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 pyrophosphatase#PC00196 HUMAN|HGNC=12749|UniProtKB=Q9GZY6 Q9GZY6 LAT2 PTHR15646:SF5 LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 2 LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 2 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;activation of immune response#GO:0002253;calcium-mediated signaling#GO:0019722;B cell receptor signaling pathway#GO:0050853;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;B cell activation#GO:0042113;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;cell activation#GO:0001775;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=9397|UniProtKB=Q9ULU4 Q9ULU4 ZMYND8 PTHR46453:SF3 PROTEIN KINASE C-BINDING PROTEIN 1 PROTEIN KINASE C-BINDING PROTEIN 1 HUMAN|HGNC=22048|UniProtKB=P60323 P60323 NANOS3 PTHR12887:SF12 NANOS PROTEIN NANOS HOMOLOG 3 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;reproductive process#GO:0022414;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;peptide metabolic process#GO:0006518;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;biosynthetic process#GO:0009058;translation#GO:0006412;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;multi-organism process#GO:0051704;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=21102|UniProtKB=Q8WV19 Q8WV19 SFT2D1 PTHR23137:SF24 UNCHARACTERIZED VESICLE TRANSPORT PROTEIN SFT2A HUMAN|HGNC=3151|UniProtKB=P30084 P30084 ECHS1 PTHR11941:SF54 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE, MITOCHONDRIAL lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 hydratase#PC00120 HUMAN|HGNC=11045|UniProtKB=P48065 P48065 SLC6A12 PTHR11616:SF118 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT BETAINE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;neurotransmitter binding#GO:0042165;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=25424|UniProtKB=Q8N567 Q8N567 ZCCHC9 PTHR46242:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 ZCCHC9 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 HUMAN|HGNC=30370|UniProtKB=Q5T9S5 Q5T9S5 CCDC18 PTHR18875:SF8 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO COILED-COIL DOMAIN-CONTAINING PROTEIN 18 cytoskeletal protein#PC00085 HUMAN|HGNC=29024|UniProtKB=O15084 O15084 ANKRD28 PTHR24123:SF75 ANKYRIN REPEAT-CONTAINING SERINE/THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY ANKYRIN REPEAT SUBUNIT A scaffold/adaptor protein#PC00226 HUMAN|HGNC=21106|UniProtKB=A1A5C7 A1A5C7 SLC22A23 PTHR24064:SF192 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 23 secondary carrier transporter#PC00258 HUMAN|HGNC=1070|UniProtKB=P12645 P12645 BMP3 PTHR11848:SF144 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 3 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=34379|UniProtKB=A6NEY8 A6NEY8 PRORSD1P PTHR31423:SF3 YBAK DOMAIN-CONTAINING PROTEIN PROLYL-TRNA SYNTHETASE ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED HUMAN|HGNC=4169|UniProtKB=O60861 O60861 GAS7 PTHR23065:SF57 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 7 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell projection morphogenesis#GO:0048858;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;plasma membrane bounded cell projection morphogenesis#GO:0120039;generation of neurons#GO:0048699;cell part morphogenesis#GO:0032990 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=28084|UniProtKB=Q2M1V0 Q2M1V0 ISX PTHR24329:SF362 HOMEOBOX PROTEIN ARISTALESS INTESTINE-SPECIFIC HOMEOBOX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=26335|UniProtKB=Q96LP2 Q96LP2 FAM81B PTHR22420:SF5 UNCHARACTERIZED PROTEIN FAM81B HUMAN|HGNC=356|UniProtKB=Q9Y4K1 Q9Y4K1 CRYBG1 PTHR11818:SF2 BETA/GAMMA CRYSTALLIN BETA/GAMMA CRYSTALLIN DOMAIN-CONTAINING PROTEIN 1 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=18794|UniProtKB=Q75N90 Q75N90 FBN3 PTHR24039:SF0 FIBRILLIN-RELATED FIBRILLIN-3 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=24670|UniProtKB=Q53EP0 Q53EP0 FNDC3B PTHR24099:SF19 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 3B ubiquitin-protein ligase#PC00234 HUMAN|HGNC=45|UniProtKB=P21439 P21439 ABCB4 PTHR24221:SF241 ATP-BINDING CASSETTE SUB-FAMILY B PHOSPHATIDYLCHOLINE TRANSLOCATOR ABCB4 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;phospholipid transporter activity#GO:0005548;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;cellular process#GO:0009987;lipid transport#GO:0006869;amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=17838|UniProtKB=Q9BYG3 Q9BYG3 NIFK PTHR46754:SF1 MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28178|UniProtKB=Q96NT0 Q96NT0 CCDC115 PTHR31996:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 115 COILED-COIL DOMAIN-CONTAINING PROTEIN 115 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=20738|UniProtKB=Q86TM6 Q86TM6 SYVN1 PTHR22765:SF213 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE SYNOVIOLIN ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|Gene=OVOS1|UniProtKB=Q6IE37 Q6IE37 OVOS1 PTHR11412:SF150 MACROGLOBULIN / COMPLEMENT OVOSTATIN HOMOLOG 1-RELATED protease inhibitor#PC00191 HUMAN|HGNC=28391|UniProtKB=Q96L08 Q96L08 SUSD3 PTHR46879:SF1 SUSHI DOMAIN-CONTAINING PROTEIN 3 SUSHI DOMAIN-CONTAINING PROTEIN 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=30410|UniProtKB=Q9BXA6 Q9BXA6 TSSK6 PTHR24343:SF166 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE/THREONINE-PROTEIN KINASE 6 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=4044|UniProtKB=O60353 O60353 FZD6 PTHR11309:SF75 FRIZZLED FRIZZLED-6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 HUMAN|Gene=YI025_HUMAN|UniProtKB=Q8N1Y9 Q8N1Y9 - PTHR34344:SF1 UPF0184 PROTEIN C9ORF16 UPF0184 PROTEIN C9ORF16 HUMAN|HGNC=26989|UniProtKB=Q6ZNG9 Q6ZNG9 KRBA2 PTHR45935:SF2 PROTEIN ZBED8-RELATED KRAB-A DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=49566|UniProtKB=P0DO97 P0DO97 CCDC192 PTHR38580:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 192 COILED-COIL DOMAIN-CONTAINING PROTEIN 192 HUMAN|HGNC=11715|UniProtKB=Q15562 Q15562 TEAD2 PTHR11834:SF5 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;hippo signaling#GO:0035329;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=6226|UniProtKB=Q96RP8 Q96RP8 KCNA7 PTHR11537:SF155 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 7 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=223|UniProtKB=Q9UKP4 Q9UKP4 ADAMTS7 PTHR13723:SF142 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 7 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=29682|UniProtKB=Q969S9 Q969S9 GFM2 PTHR43261:SF1 TRANSLATION ELONGATION FACTOR G-RELATED RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;cellular process#GO:0009987;organelle organization#GO:0006996;organelle disassembly#GO:1903008 translation elongation factor#PC00222 HUMAN|HGNC=14544|UniProtKB=Q96J92 Q96J92 WNK4 PTHR13902:SF114 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE/THREONINE-PROTEIN KINASE WNK4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;transferase activity, transferring phosphorus-containing groups#GO:0016772;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;transporter activity#GO:0005215;kinase activity#GO:0016301;channel activity#GO:0015267;protein kinase activity#GO:0004672;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;transferase activity#GO:0016740;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;protein serine/threonine kinase activity#GO:0004674;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890 regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of transmembrane transport#GO:0034764;regulation of transmembrane transporter activity#GO:0022898;intracellular signal transduction#GO:0035556;regulation of transporter activity#GO:0032409;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of transport#GO:0051050;cell communication#GO:0007154;negative regulation of transport#GO:0051051;ion transmembrane transport#GO:0034220;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;regulation of ion transport#GO:0043269;multicellular organismal process#GO:0032501;positive regulation of ion transport#GO:0043270;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;ion homeostasis#GO:0050801;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;positive regulation of ion transmembrane transporter activity#GO:0032414;homeostatic process#GO:0042592;protein phosphorylation#GO:0006468;cellular process#GO:0009987;chemical homeostasis#GO:0048878;localization#GO:0051179;response to stimulus#GO:0050896;sodium ion transport#GO:0006814;positive regulation of transporter activity#GO:0032411;positive regulation of ion transmembrane transport#GO:0034767;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;sodium ion transmembrane transport#GO:0035725 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=937|UniProtKB=Q99933 Q99933 BAG1 PTHR12329:SF16 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234;chaperone binding#GO:0051087;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 biological regulation#GO:0065007;regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Apoptosis signaling pathway#P00006>Bag#P00278 HUMAN|HGNC=30881|UniProtKB=Q9NP73 Q9NP73 ALG13 PTHR12867:SF7 GLYCOSYL TRANSFERASE-RELATED BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE TRANSFERASE AND DEUBIQUITINASE ALG13-RELATED transferase#PC00220 HUMAN|HGNC=1987|UniProtKB=Q99967 Q99967 CITED2 PTHR17045:SF7 MELANOCYTE SPECIFIC GENE RELATED CITED CBP/P300-INTERACTING TRANSACTIVATOR 2 transcription cofactor#PC00217 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 HUMAN|HGNC=25636|UniProtKB=Q6DN12 Q6DN12 MCTP2 PTHR45911:SF2 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;regulation of cellular process#GO:0050794;regulation of neurotransmitter levels#GO:0001505;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;export from cell#GO:0140352 bounding membrane of organelle#GO:0098588;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;intrinsic component of membrane#GO:0031224;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=15506|UniProtKB=Q9BSV6 Q9BSV6 TSEN34 PTHR13070:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on a tRNA#GO:0140101 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 endoribonuclease#PC00094 HUMAN|HGNC=646|UniProtKB=P10398 P10398 ARAF PTHR44329:SF55 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED SERINE/THREONINE-PROTEIN KINASE A-RAF transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>Raf#P01417;Integrin signalling pathway#P00034>Raf#P00924;EGF receptor signaling pathway#P00018>Raf-1#P00560;PDGF signaling pathway#P00047>Raf#P01161;Angiogenesis#P00005>Raf#P00243;Endothelin signaling pathway#P00019>Raf-1#P00587;Interleukin signaling pathway#P00036>Raf#P00983;FGF signaling pathway#P00021>Raf-1#P00643;CCKR signaling map#P06959>A-Raf#P07220;Ras Pathway#P04393>Raf#P04556;B cell activation#P00010>Raf#P00381;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Raf-1#P00843;T cell activation#P00053>Raf#P01311 HUMAN|HGNC=37214|UniProtKB=B2RXH4 B2RXH4 BTBD18 PTHR47639:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 18 BTB/POZ DOMAIN-CONTAINING PROTEIN 18 HUMAN|HGNC=21065|UniProtKB=O95847 O95847 SLC25A27 PTHR45618:SF8 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 4 response to cold#GO:0009409;response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950 secondary carrier transporter#PC00258 HUMAN|HGNC=14305|UniProtKB=Q8N3K9 Q8N3K9 CMYA5 PTHR24099:SF7 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED CARDIOMYOPATHY-ASSOCIATED PROTEIN 5 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=20045|UniProtKB=Q9H840 Q9H840 GEMIN7 PTHR14679:SF1 GEM-ASSOCIATED PROTEIN 7 GEM-ASSOCIATED PROTEIN 7 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;intracellular#GO:0005622 HUMAN|HGNC=11061|UniProtKB=Q8WY07 Q8WY07 SLC7A3 PTHR43243:SF20 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046 HUMAN|HGNC=396|UniProtKB=P13196 P13196 ALAS1 PTHR13693:SF50 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 5-AMINOLEVULINATE SYNTHASE, NONSPECIFIC, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 cellular aromatic compound metabolic process#GO:0006725;response to hypoxia#GO:0001666;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;porphyrin-containing compound metabolic process#GO:0006778;biosynthetic process#GO:0009058;heme biosynthetic process#GO:0006783;system development#GO:0048731;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;pigment biosynthetic process#GO:0046148;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;response to oxygen levels#GO:0070482;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152;myeloid cell differentiation#GO:0030099;tetrapyrrole metabolic process#GO:0033013;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;multicellular organism development#GO:0007275;response to decreased oxygen levels#GO:0036293;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;erythrocyte differentiation#GO:0030218;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cell development#GO:0048468;immune system process#GO:0002376;response to stimulus#GO:0050896;response to stress#GO:0006950;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;aromatic compound biosynthetic process#GO:0019438 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transaminase#PC00216 HUMAN|HGNC=37931|UniProtKB=Q96GX2 Q96GX2 ATXN7L3B PTHR47733:SF1 ATAXIN-7 LIKE PROTEIN 3B, ATXN7L3B ATAXIN-7-LIKE PROTEIN 3B regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=17875|UniProtKB=Q96CD0 Q96CD0 FBXL8 PTHR16134:SF119 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX/LRR-REPEAT PROTEIN 8 HUMAN|HGNC=26573|UniProtKB=Q96LX8 Q96LX8 ZNF597 PTHR24393:SF117 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 597 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20730|UniProtKB=Q7Z3E5 Q7Z3E5 ARMC9 PTHR14881:SF4 LISH DOMAIN-CONTAINING PROTEIN ARMC9 LISH DOMAIN-CONTAINING PROTEIN ARMC9 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=4718|UniProtKB=P10412 P10412 H1-4 PTHR11467:SF20 HISTONE H1 HISTONE H1.4 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of chromatin silencing#GO:0031935;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of chromatin silencing#GO:0031936;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of chromatin organization#GO:1902275;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;chromosome condensation#GO:0030261;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of DNA recombination#GO:0000018;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone#PC00118 HUMAN|HGNC=26244|UniProtKB=Q8IW35 Q8IW35 CEP97 PTHR45973:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED CENTROSOMAL PROTEIN OF 97 KDA phosphatase modulator#PC00184 HUMAN|HGNC=10988|UniProtKB=Q9H1K4 Q9H1K4 SLC25A18 PTHR45678:SF11 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED MITOCHONDRIAL GLUTAMATE CARRIER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 dicarboxylic acid transport#GO:0006835;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;electron transport chain#GO:0022900;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;anion transport#GO:0006820;respiratory electron transport chain#GO:0022904;oxidation-reduction process#GO:0055114;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152;cellular respiration#GO:0045333;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;generation of precursor metabolites and energy#GO:0006091;ion transport#GO:0006811;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;mitochondrial transport#GO:0006839;localization#GO:0051179;C4-dicarboxylate transport#GO:0015740;organic acid transmembrane transport#GO:1903825 secondary carrier transporter#PC00258 HUMAN|HGNC=22412|UniProtKB=Q8N0U4 Q8N0U4 FAM185A PTHR34094:SF1 FAMILY NOT NAMED PROTEIN FAM185A HUMAN|HGNC=11782|UniProtKB=P07101 P07101 TH PTHR11473:SF18 AROMATIC AMINO ACID HYDROXYLASE TYROSINE 3-MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;tyrosine metabolic process#GO:0006570;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;catecholamine metabolic process#GO:0006584;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid family metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;aromatic compound biosynthetic process#GO:0019438;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;intracellular#GO:0005622;neuronal cell body#GO:0043025;perikaryon#GO:0043204;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;plasma membrane#GO:0005886 Dopamine receptor mediated signaling pathway#P05912>TH#P05970;Parkinson disease#P00049>TH#P01241;Nicotine pharmacodynamics pathway#P06587>TH#P06614;Adrenaline and noradrenaline biosynthesis#P00001>TH#P00062 HUMAN|HGNC=10050|UniProtKB=Q05823 Q05823 RNASEL PTHR24141:SF1 2-5A-DEPENDENT RIBONUCLEASE 2-5A-DEPENDENT RIBONUCLEASE catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=24276|UniProtKB=Q9Y512 Q9Y512 SAMM50 PTHR12815:SF18 SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein insertion into membrane#GO:0051205;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 bounding membrane of organelle#GO:0098588;mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=18185|UniProtKB=Q9UJM3 Q9UJM3 ERRFI1 PTHR14254:SF5 GENE 33 POLYPEPTIDE ERBB RECEPTOR FEEDBACK INHIBITOR 1 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;skin development#GO:0043588;regulation of biological process#GO:0050789;system development#GO:0048731;epidermis development#GO:0008544;cell differentiation#GO:0030154;regulation of epithelial cell differentiation#GO:0030856;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;epidermal growth factor receptor signaling pathway#GO:0007173;epidermal cell differentiation#GO:0009913;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;negative regulation of response to stimulus#GO:0048585;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;multicellular organism development#GO:0007275;cell communication#GO:0007154;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;tissue development#GO:0009888;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562 HUMAN|HGNC=26305|UniProtKB=Q6P3V2 Q6P3V2 ZNF585A PTHR24376:SF197 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 585A-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4129|UniProtKB=Q86SF2 Q86SF2 GALNT7 PTHR11675:SF68 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 7 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=14465|UniProtKB=Q96T54 Q96T54 KCNK17 PTHR11003:SF319 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 17 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=7514|UniProtKB=Q99102 Q99102 MUC4 PTHR13802:SF58 MUCIN 4-RELATED MUCIN-4 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=14959|UniProtKB=Q96T37 Q96T37 RBM15 PTHR23189:SF43 RNA RECOGNITION MOTIF-CONTAINING RNA-BINDING PROTEIN 15 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|Ensembl=ENSG00000284439|UniProtKB=A0A1W2PRV1 A0A1W2PRV1 TAF11L3 PTHR13218:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TAFII28 DOMAIN-CONTAINING PROTEIN transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=9767|UniProtKB=O00194 O00194 RAB27B PTHR47977:SF33 LD21953P-RELATED RAS-RELATED PROTEIN RAB-27B vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;pigmentation#GO:0043473;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;positive regulation of exocytosis#GO:0045921;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;establishment of vesicle localization#GO:0051650;vesicle organization#GO:0016050;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;vesicle localization#GO:0051648;positive regulation of secretion#GO:0051047;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;positive regulation of secretion by cell#GO:1903532;export from cell#GO:0140352 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=14489|UniProtKB=Q9NZE8 Q9NZE8 MRPL35 PTHR15909:SF0 39S RIBOSOMAL PROTEIN L35, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L35, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ribosomal protein#PC00202 HUMAN|HGNC=26072|UniProtKB=Q8IVU3 Q8IVU3 HERC6 PTHR45622:SF11 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC6-RELATED ubiquitin-protein ligase#PC00234 HUMAN|HGNC=1253|UniProtKB=P58499 P58499 FAM3B PTHR14592:SF2 UNCHARACTERIZED FAM3 PROTEIN FAM3B extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=13085|UniProtKB=O15209 O15209 ZBTB22 PTHR24414:SF4 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 22 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=18745|UniProtKB=Q9Y6G9 Q9Y6G9 DYNC1LI1 PTHR12688:SF2 DYNEIN LIGHT INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 LIGHT INTERMEDIATE CHAIN 1 dynein heavy chain binding#GO:0045504;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987 microtubule organizing center#GO:0005815;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=11247|UniProtKB=O43291 O43291 SPINT2 PTHR47247:SF1 KUNITZ-TYPE PROTEASE INHIBITOR 2 KUNITZ-TYPE PROTEASE INHIBITOR 2 protease inhibitor#PC00191 HUMAN|HGNC=9401|UniProtKB=Q02156 Q02156 PRKCE PTHR24356:SF159 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C EPSILON TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>PKC#P00565;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Apoptosis signaling pathway#P00006>PKCs#P00318;Gonadotropin-releasing hormone receptor pathway#P06664>nPKCs#P06852;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs(3)#P06850;CCKR signaling map#P06959>PKCepsilon#P07054;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;VEGF signaling pathway#P00056>PKC#P01425;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;FGF signaling pathway#P00021>PKC#P00648;Gonadotropin-releasing hormone receptor pathway#P06664>PKCe/theta#P06798;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 HUMAN|HGNC=22940|UniProtKB=Q86W28 Q86W28 NLRP8 PTHR45690:SF8 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 8 HUMAN|HGNC=32235|UniProtKB=Q8N0T1 Q8N0T1 RBIS PTHR35544:SF4 RIBOSOMAL BIOGENESIS FACTOR RIBOSOMAL BIOGENESIS FACTOR cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18273|UniProtKB=Q96PN7 Q96PN7 TRERF1 PTHR16089:SF19 REST COREPRESSOR COREST PROTEIN-RELATED TRANSCRIPTIONAL-REGULATING FACTOR 1 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 HUMAN|HGNC=21159|UniProtKB=Q8WVD5 Q8WVD5 RNF141 PTHR12109:SF3 RING FINGER PROTEIN 141-RELATED RING FINGER PROTEIN 141 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=9813|UniProtKB=P54727 P54727 RAD23B PTHR10621:SF13 UV EXCISION REPAIR PROTEIN RAD23 UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG B proteasome binding#GO:0070628;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;ubiquitin binding#GO:0043130;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 damaged DNA-binding protein#PC00086 HUMAN|HGNC=15964|UniProtKB=Q13117 Q13117 DAZ2 PTHR11176:SF8 BOULE-RELATED DELETED IN AZOOSPERMIA PROTEIN 1-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of translational initiation#GO:0045948;gene expression#GO:0010467;regulation of translational initiation#GO:0006446;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;translational initiation#GO:0006413;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=37260|UniProtKB=Q8N5G0 Q8N5G0 SMIM20 PTHR34923:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 20 SMALL INTEGRAL MEMBRANE PROTEIN 20 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=10810|UniProtKB=O00141 O00141 SGK1 PTHR24356:SF300 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE SGK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular protein metabolic process#GO:0044267;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=18352|UniProtKB=Q9NSP4 Q9NSP4 CENPM PTHR34436:SF1 CENTROMERE PROTEIN M CENTROMERE PROTEIN M HUMAN|HGNC=13238|UniProtKB=Q9HDC9 Q9HDC9 APMAP PTHR10426:SF99 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HUMAN|HGNC=17616|UniProtKB=Q8NFM7 Q8NFM7 IL17RD PTHR15583:SF14 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR D signaling receptor activity#GO:0038023;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;cytokine binding#GO:0019955 transmembrane signal receptor#PC00197 HUMAN|HGNC=16803|UniProtKB=Q15386 Q15386 UBE3C PTHR45700:SF2 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3C ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 HUMAN|HGNC=13664|UniProtKB=Q9UPN3 Q9UPN3 MACF1 PTHR23169:SF25 ENVOPLAKIN MICROTUBULE-ACTIN CROSS-LINKING FACTOR 1, ISOFORMS 1/2/3/5 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;biological adhesion#GO:0022610;regulation of cellular component organization#GO:0051128;wound healing#GO:0042060;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;cell-substrate junction assembly#GO:0007044;response to wounding#GO:0009611;response to stress#GO:0006950;microtubule-based process#GO:0007017;cell-matrix adhesion#GO:0007160;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;cell junction organization#GO:0034330;biological regulation#GO:0065007;cell junction assembly#GO:0034329;cytoskeleton organization#GO:0007010;regulation of cell junction assembly#GO:1901888;regulation of cell adhesion#GO:0030155;intermediate filament cytoskeleton organization#GO:0045104 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874 intermediate filament binding protein#PC00130 HUMAN|HGNC=25017|UniProtKB=Q9P0T4 Q9P0T4 ZNF581 PTHR24390:SF76 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 581 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=22974|UniProtKB=Q8N4G2 Q8N4G2 ARL14 PTHR11711:SF29 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 14 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein#PC00020 HUMAN|HGNC=1395|UniProtKB=O95180 O95180 CACNA1H PTHR10037:SF192 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1H calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;system process#GO:0003008;transport#GO:0006810;regulation of secretion by cell#GO:1903530;action potential#GO:0001508;regulation of localization#GO:0032879;cation transport#GO:0006812;calcium ion transport#GO:0006816;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;positive regulation of exocytosis#GO:0045921;regulation of secretion#GO:0051046;secretion#GO:0046903;synaptic signaling#GO:0099536;divalent inorganic cation transport#GO:0072511;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;metal ion transport#GO:0030001;ion transport#GO:0006811;regulation of membrane potential#GO:0042391;positive regulation of secretion#GO:0051047;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cell communication#GO:0007154;nervous system process#GO:0050877;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;positive regulation of cellular process#GO:0048522;localization#GO:0051179;calcium ion import#GO:0070509;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of secretion by cell#GO:1903532;export from cell#GO:0140352 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=9534|UniProtKB=P28066 P28066 PSMA5 PTHR11599:SF14 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-5 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome core complex, alpha-subunit complex#GO:0019773;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=14625|UniProtKB=Q9BXL8 Q9BXL8 CDCA4 PTHR16277:SF6 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 CELL DIVISION CYCLE-ASSOCIATED PROTEIN 4 molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=11201|UniProtKB=P35711 P35711 SOX5 PTHR45789:SF3 FI18025P1 TRANSCRIPTION FACTOR SOX-5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;connective tissue development#GO:0061448;chondrocyte differentiation#GO:0002062;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;cartilage development#GO:0051216;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=29181|UniProtKB=Q9BQ70 Q9BQ70 TCF25 PTHR22684:SF0 NULP1-RELATED TRANSCRIPTION FACTOR 25 HUMAN|HGNC=561|UniProtKB=O95782 O95782 AP2A1 PTHR22780:SF33 ADAPTIN, ALPHA/GAMMA/EPSILON AP-2 COMPLEX SUBUNIT ALPHA-1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;plasma membrane region#GO:0098590;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Huntington disease#P00029>alpha-Adaptin#P00782 HUMAN|HGNC=13994|UniProtKB=Q9NQV7 Q9NQV7 PRDM9 PTHR16515:SF44 PR DOMAIN ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9 N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;telophase#GO:0051326;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;nucleobase-containing compound metabolic process#GO:0006139;M phase#GO:0000279;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;positive regulation of biological process#GO:0048518;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;meiosis I cell cycle phase#GO:0098764;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;regulation of cellular process#GO:0050794;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of organelle organization#GO:0010638;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;positive regulation of cell cycle process#GO:0090068;meiotic cell cycle process#GO:1903046;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;reciprocal meiotic recombination#GO:0007131;cell cycle phase#GO:0022403;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;regulation of nuclear division#GO:0051783;regulation of reproductive process#GO:2000241;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of meiotic cell cycle#GO:0051445;meiotic nuclear division#GO:0140013;regulation of nucleobase-containing compound metabolic process#GO:0019219;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;biological phase#GO:0044848;homologous recombination#GO:0035825;regulation of DNA recombination#GO:0000018;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=17556|UniProtKB=Q9Y2X0 Q9Y2X0 MED16 PTHR13224:SF6 THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 16 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=20485|UniProtKB=O75317 O75317 USP12 PTHR24006:SF647 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=16629|UniProtKB=O95398 O95398 RAPGEF3 PTHR23113:SF24 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 3 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=25935|UniProtKB=Q9NXX6 Q9NXX6 NSMCE4A PTHR16140:SF2 UNCHARACTERIZED NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 HOMOLOG A DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of response to DNA damage stimulus#GO:2001020;cellular macromolecule metabolic process#GO:0044260;positive regulation of response to DNA damage stimulus#GO:2001022;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12151|UniProtKB=A0A0B4J262 A0A0B4J262 TRAV8-6 PTHR19367:SF11 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-6 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=16783|UniProtKB=Q6P1J9 Q6P1J9 CDC73 PTHR12466:SF8 CDC73 DOMAIN PROTEIN PARAFIBROMIN basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;ribonucleoprotein complex subunit organization#GO:0071826;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of transcription elongation from RNA polymerase II promoter#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA 3'-end processing#GO:0031124;regulation of DNA-templated transcription, elongation#GO:0032784;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;DNA-templated transcription, elongation#GO:0006354;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of transcription elongation from RNA polymerase II promoter#GO:0034243;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;transcription elongation from RNA polymerase II promoter#GO:0006368;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=30600|UniProtKB=Q5T124 Q5T124 UBXN11 PTHR23333:SF4 UBX DOMAIN CONTAINING PROTEIN UBX DOMAIN-CONTAINING PROTEIN 11 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-binding activity modulator#PC00095 HUMAN|HGNC=12337|UniProtKB=Q9UL62 Q9UL62 TRPC5 PTHR10117:SF76 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 5 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 HUMAN|HGNC=12463|UniProtKB=P0CG47 P0CG47 UBB PTHR10666:SF384 UBIQUITIN POLYUBIQUITIN-B enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11237|UniProtKB=Q9UQ90 Q9UQ90 SPG7 PTHR43655:SF8 ATP-DEPENDENT PROTEASE PARAPLEGIN metalloprotease#PC00153 HUMAN|HGNC=16876|UniProtKB=Q9HBZ2 Q9HBZ2 ARNT2 PTHR23042:SF6 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=25620|UniProtKB=Q8WWA1 Q8WWA1 TMEM40 PTHR16108:SF2 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 40 HUMAN|HGNC=29601|UniProtKB=Q9BSJ5 Q9BSJ5 C17orf80 PTHR16270:SF5 HYPOTHETICAL LOC287798 HYPOTHETICAL LOC287798 HUMAN|HGNC=8711|UniProtKB=Q9UN71 Q9UN71 PCDHGB4 PTHR24028:SF117 CADHERIN-87A PROTOCADHERIN GAMMA-B4 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=24080|UniProtKB=Q8WW43 Q8WW43 APH1B PTHR12889:SF1 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1B hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;proteolysis#GO:0006508;biological regulation#GO:0065007;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;Notch signaling pathway#GO:0007219 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;intrinsic component of plasma membrane#GO:0031226;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 protease#PC00190 Alzheimer disease-presenilin pathway#P00004>Aph-1#P00170;Notch signaling pathway#P00045>Aph-1#P01109;Alzheimer disease-amyloid secretase pathway#P00003>Aph-1#P00091 HUMAN|HGNC=19182|UniProtKB=O94885 O94885 SASH1 PTHR12301:SF3 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM AND SH3 DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=2060|UniProtKB=O14967 O14967 CLGN PTHR11073:SF7 CALRETICULIN AND CALNEXIN CALMEGIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;protein folding#GO:0006457;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 chaperone#PC00072 HUMAN|HGNC=18589|UniProtKB=Q9BZE7 Q9BZE7 C22orf23 PTHR28348:SF1 UPF0193 PROTEIN EVG1 UPF0193 PROTEIN EVG1 HUMAN|HGNC=10426|UniProtKB=P46782 P46782 RPS5 PTHR11205:SF34 RIBOSOMAL PROTEIN S7 40S RIBOSOMAL PROTEIN S5 structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;ribosomal small subunit biogenesis#GO:0042274;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=7972|UniProtKB=P49116 P49116 NR2C2 PTHR24083:SF48 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of developmental process#GO:0051094;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C4 zinc finger nuclear receptor#PC00169 CCKR signaling map#P06959>TAK1#P07170 HUMAN|HGNC=10316|UniProtKB=P62829 P62829 RPL23 PTHR11761:SF22 50S/60S RIBOSOMAL PROTEIN L14/L23 60S RIBOSOMAL PROTEIN L23 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=24768|UniProtKB=Q6ZV29 Q6ZV29 PNPLA7 PTHR14226:SF23 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 7 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 esterase#PC00097 HUMAN|HGNC=26846|UniProtKB=Q86WS4 Q86WS4 C12orf40 PTHR35158:SF1 CDNA SEQUENCE CN725425 CDNA SEQUENCE CN725425 HUMAN|HGNC=5345|UniProtKB=P13598 P13598 ICAM2 PTHR13771:SF3 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=28189|UniProtKB=Q9BRQ3 Q9BRQ3 NUDT22 PTHR31835:SF1 URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT22 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 phosphatase#PC00181 HUMAN|HGNC=14502|UniProtKB=P82664 P82664 MRPS10 PTHR13334:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S10 28S RIBOSOMAL PROTEIN S10, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ribosomal protein#PC00202 HUMAN|HGNC=11862|UniProtKB=O60478 O60478 GPR137B PTHR15146:SF0 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137B regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of intracellular signal transduction#GO:1902531;tissue remodeling#GO:0048771;osteoclast differentiation#GO:0030316;regulation of biological process#GO:0050789;bone remodeling#GO:0046849;regulation of biological quality#GO:0065008;regulation of signal transduction#GO:0009966;regulation of tissue remodeling#GO:0034103;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;TOR signaling#GO:0031929;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;immune system development#GO:0002520;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;multicellular organismal homeostasis#GO:0048871;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of bone remodeling#GO:0046850;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;system development#GO:0048731;regulation of hemopoiesis#GO:1903706;tissue homeostasis#GO:0001894;positive regulation of TOR signaling#GO:0032008;bone resorption#GO:0045453;hemopoiesis#GO:0030097;catabolic process#GO:0009056;regulation of immune system process#GO:0002682;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;myeloid cell differentiation#GO:0030099;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;TORC1 signaling#GO:0038202;regulation of autophagy#GO:0010506;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of developmental process#GO:0050793;regulation of bone resorption#GO:0045124;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=26400|UniProtKB=Q5T8I9 Q5T8I9 HENMT1 PTHR21404:SF3 HEN1 SMALL RNA 2'-O-METHYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression#GO:0010468;regulation of gene expression, epigenetic#GO:0040029;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA interference#GO:0016246;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;gene silencing by RNA#GO:0031047;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;posttranscriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26313|UniProtKB=Q499Z3 Q499Z3 SLFNL1 PTHR12155:SF29 SCHLAFEN SCHLAFEN-LIKE PROTEIN 1 HUMAN|HGNC=12410|UniProtKB=Q9NY65 Q9NY65 TUBA8 PTHR11588:SF140 TUBULIN TUBULIN ALPHA-8 CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 HUMAN|HGNC=26105|UniProtKB=Q7Z736 Q7Z736 PLEKHH3 PTHR46049:SF5 FAMILY NOT NAMED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=29533|UniProtKB=Q9GZZ1 Q9GZZ1 NAA50 PTHR42919:SF8 N-ALPHA-ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 50 acetyltransferase#PC00038 HUMAN|HGNC=8960|UniProtKB=Q92535 Q92535 PIGC PTHR12982:SF1 PHOSPHATIDYLINOSITOL GLYCAN, CLASS C PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=808|UniProtKB=Q9UN42 Q9UN42 ATP1B4 PTHR11523:SF12 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT PROTEIN ATP1B4 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;enzyme activator activity#GO:0008047;active transmembrane transporter activity#GO:0022804;enzyme regulator activity#GO:0030234;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;nucleoside-triphosphatase activity#GO:0017111;ATPase activator activity#GO:0001671;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;regulation of nitrogen compound metabolic process#GO:0051171;inorganic cation transmembrane transport#GO:0098662;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;establishment of localization#GO:0051234;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;potassium ion transport#GO:0006813;cellular cation homeostasis#GO:0030003;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;cation homeostasis#GO:0055080;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;metal ion homeostasis#GO:0055065;regulation of metabolic process#GO:0019222;export from cell#GO:0140352;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;cellular metal ion homeostasis#GO:0006875;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;biosynthetic process#GO:0009058;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;ion homeostasis#GO:0050801;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;metal ion transport#GO:0030001;cellular monovalent inorganic cation homeostasis#GO:0030004;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;monovalent inorganic cation homeostasis#GO:0055067;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;chemical homeostasis#GO:0048878;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;nucleic acid metabolic process#GO:0090304;sodium ion transport#GO:0006814;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;sodium ion transmembrane transport#GO:0035725 envelope#GO:0031975;membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;vacuole#GO:0005773;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;integral component of membrane#GO:0016021;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=23747|UniProtKB=Q9HA82 Q9HA82 CERS4 PTHR12560:SF6 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 4 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=25137|UniProtKB=A0AVI4 A0AVI4 TMEM129 PTHR31322:SF2 E3 UBIQUITIN-PROTEIN LIGASE TM129 E3 UBIQUITIN-PROTEIN LIGASE TM129 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=8071|UniProtKB=Q9UBU9 Q9UBU9 NXF1 PTHR10662:SF27 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=1724|UniProtKB=Q9UJX2 Q9UJX2 CDC23 PTHR12558:SF10 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 23 HOMOLOG cell division#GO:0051301;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=19731|UniProtKB=Q6PKH6 Q6PKH6 DHRS4L2 PTHR43943:SF8 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 4-RELATED dehydrogenase#PC00092 HUMAN|HGNC=30423|UniProtKB=Q9HB71 Q9HB71 CACYBP PTHR13164:SF3 CALICYLIN BINDING PROTEIN CALCYCLIN-BINDING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=1476|UniProtKB=P07384 P07384 CAPN1 PTHR10183:SF284 CALPAIN CALPAIN-1 CATALYTIC SUBUNIT cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=6700|UniProtKB=Q14114 Q14114 LRP8 PTHR24270:SF3 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 8 apolipoprotein#PC00052 HUMAN|HGNC=28568|UniProtKB=O43247 O43247 TEX33 PTHR31702:SF2 TESTIS-EXPRESSED PROTEIN 33 TESTIS-EXPRESSED PROTEIN 33 HUMAN|HGNC=14524|UniProtKB=O60271 O60271 SPAG9 PTHR13886:SF2 JNK/SAPK-ASSOCIATED PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;transport#GO:0006810;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of JNK cascade#GO:0046330;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;positive regulation of protein serine/threonine kinase activity#GO:0071902;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=1582|UniProtKB=P24385 P24385 CCND1 PTHR10177:SF67 CYCLINS G1/S-SPECIFIC CYCLIN-D1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of mitotic cell cycle#GO:0045931;regulation of G1/S transition of mitotic cell cycle#GO:2000045;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of phosphate metabolic process#GO:0019220;regulation of cyclin-dependent protein kinase activity#GO:1904029;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of cell cycle process#GO:0090068;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of protein kinase activity#GO:0045859;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of mitotic cell cycle#GO:0007346;regulation of transferase activity#GO:0051338 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 CCKR signaling map#P06959>CCND1#G06986;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;CCKR signaling map#P06959>CCND1#G07280;PI3 kinase pathway#P00048>Cyclin d#G01546;Cell cycle#P00013>Cyclin D#P00484 HUMAN|HGNC=18519|UniProtKB=Q5JTY5 Q5JTY5 CBWD3 PTHR13748:SF31 COBW-RELATED COBW DOMAIN-CONTAINING PROTEIN 1-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=15975|UniProtKB=O75995 O75995 SASH3 PTHR12301:SF5 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED SAM AND SH3 DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=7172|UniProtKB=Q9Y5R2 Q9Y5R2 MMP24 PTHR10201:SF138 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-24 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Membrane metalloprotease#P00141;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=19663|UniProtKB=Q9UBI6 Q9UBI6 GNG12 PTHR13809:SF9 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-12 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Nicotine pharmacodynamics pathway#P06587>GNG#P06590;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 HUMAN|HGNC=24358|UniProtKB=Q9H2G4 Q9H2G4 TSPYL2 PTHR11875:SF72 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 2 protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|Gene=YE016_HUMAN|UniProtKB=A6NLC8 A6NLC8 - PTHR13218:SF15 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TAF11-LIKE PROTEIN ENSP00000332601-RELATED transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=51251|UniProtKB=A0A087WV53 A0A087WV53 SPEGNB PTHR44170:SF11 PROTEIN SIDEKICK SPEG NEIGHBOR PROTEIN HUMAN|HGNC=14970|UniProtKB=Q9UNH7 Q9UNH7 SNX6 PTHR45850:SF4 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-6 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=23505|UniProtKB=Q14692 Q14692 BMS1 PTHR12858:SF2 RIBOSOME BIOGENESIS PROTEIN RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG snoRNA binding#GO:0030515;GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cleavage involved in rRNA processing#GO:0000469;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;endonucleolytic cleavage involved in rRNA processing#GO:0000478;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;90S preribosome#GO:0030686 HUMAN|HGNC=17677|UniProtKB=Q15276 Q15276 RABEP1 PTHR31179:SF5 RAB GTPASE-BINDING EFFECTOR PROTEIN RAB GTPASE-BINDING EFFECTOR PROTEIN 1 localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 HUMAN|HGNC=8086|UniProtKB=P00973 P00973 OAS1 PTHR11258:SF13 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE 1 adenylyltransferase activity#GO:0070566;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;double-stranded RNA binding#GO:0003725 response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA phosphodiester bond hydrolysis#GO:0090501;regulation of catalytic activity#GO:0050790;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;defense response to other organism#GO:0098542;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 HUMAN|HGNC=20763|UniProtKB=Q9P2R3 Q9P2R3 ANKFY1 PTHR24118:SF82 POTE ANKYRIN DOMAIN RABANKYRIN-5 membrane traffic protein#PC00150 HUMAN|HGNC=5411|UniProtKB=O14879 O14879 IFIT3 PTHR10271:SF3 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 3 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=34550|UniProtKB=A6NGN9 A6NGN9 IGLON5 PTHR42757:SF12 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED IGLON FAMILY MEMBER 5 immunoglobulin#PC00123 HUMAN|HGNC=7660|UniProtKB=P14598 P14598 NCF1 PTHR15706:SF6 SH3 MULTIPLE DOMAIN NEUTROPHIL CYTOSOL FACTOR 1-RELATED phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;catalytic activity#GO:0003824;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152 HUMAN|HGNC=30828|UniProtKB=Q96A98 Q96A98 PTH2 PTHR28585:SF1 TUBEROINFUNDIBULAR PEPTIDE OF 39 RESIDUES TUBEROINFUNDIBULAR PEPTIDE OF 39 RESIDUES HUMAN|HGNC=29223|UniProtKB=Q9ULJ7 Q9ULJ7 ANKRD50 PTHR24123:SF65 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 50 scaffold/adaptor protein#PC00226 HUMAN|HGNC=4079|UniProtKB=P31644 P31644 GABRA5 PTHR18945:SF23 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-5 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;cell junction#GO:0030054;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=26599|UniProtKB=Q8IWD4 Q8IWD4 CCDC117 PTHR36128:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 117 COILED-COIL DOMAIN-CONTAINING PROTEIN 117 HUMAN|HGNC=16153|UniProtKB=Q9NUG4 Q9NUG4 CCM2L PTHR21642:SF2 CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN-LIKE HUMAN|HGNC=6513|UniProtKB=Q14847 Q14847 LASP1 PTHR46218:SF2 LASP LIM AND SH3 DOMAIN PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 HUMAN|HGNC=30000|UniProtKB=Q3SYG4 Q3SYG4 BBS9 PTHR20991:SF0 PARATHYROID HORMONE-RESPONSIVE B1 GENE PROTEIN PTHB1 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;BBSome#GO:0034464;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=18893|UniProtKB=Q8N5I3 Q8N5I3 KCNRG PTHR14499:SF5 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING POTASSIUM CHANNEL REGULATORY PROTEIN negative regulation of biological process#GO:0048519;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;ion transport#GO:0006811;negative regulation of transport#GO:0051051;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29557|UniProtKB=Q0ZGT2 Q0ZGT2 NEXN PTHR10075:SF52 BASIGIN RELATED NEXILIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11527|UniProtKB=P21452 P21452 TACR2 PTHR46925:SF3 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED SUBSTANCE-K RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of cellular component movement#GO:0051270;regulation of microtubule-based process#GO:0032886;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;regulation of localization#GO:0032879;sperm motility#GO:0097722;cell motility#GO:0048870;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;cilium movement involved in cell motility#GO:0060294;positive regulation of cellular component movement#GO:0051272;cilium movement#GO:0003341;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;cilium-dependent cell motility#GO:0060285;reproduction#GO:0000003;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;positive regulation of biological process#GO:0048518;locomotion#GO:0040011 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;B axonemal microtubule#GO:0097650;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=5425|UniProtKB=P05014 P05014 IFNA4 PTHR11691:SF66 TYPE I INTERFERON INTERFERON ALPHA-10-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=8524|UniProtKB=Q12889 Q12889 OVGP1 PTHR11177:SF385 CHITINASE OVIDUCT-SPECIFIC GLYCOPROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;carbohydrate derivative binding#GO:0097367;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;binding#GO:0005488;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110 HUMAN|HGNC=13420|UniProtKB=Q86TP1 Q86TP1 PRUNE1 PTHR12112:SF47 BNIP - RELATED EXOPOLYPHOSPHATASE PRUNE1 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=18677|UniProtKB=Q9NXZ2 Q9NXZ2 DDX43 PTHR47958:SF17 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX43-RELATED catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 HUMAN|HGNC=29993|UniProtKB=Q8NHV9 Q8NHV9 RHOXF1 PTHR24329:SF549 HOMEOBOX PROTEIN ARISTALESS RHOX HOMEOBOX FAMILY MEMBER 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=32480|UniProtKB=Q96EL1 Q96EL1 INKA1 PTHR28615:SF1 PAK4-INHIBITOR INKA1-RELATED PAK4-INHIBITOR INKA1 protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=4238|UniProtKB=Q5VTD9 Q5VTD9 GFI1B PTHR24393:SF49 ZINC FINGER PROTEIN ZINC FINGER PROTEIN GFI-1B DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;hematopoietic or lymphoid organ development#GO:0048534;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of hemopoiesis#GO:1903706;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=18668|UniProtKB=O15156 O15156 ZBTB7B PTHR46105:SF4 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=1969|UniProtKB=O43916 O43916 CHST1 PTHR10704:SF36 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;amino sugar metabolic process#GO:0006040;cellular metabolic process#GO:0044237;aminoglycan metabolic process#GO:0006022;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=1966|UniProtKB=Q04844 Q04844 CHRNE PTHR18945:SF59 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT EPSILON signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=18395|UniProtKB=O95968 O95968 SCGB1D1 PTHR11332:SF5 SECRETOGLOBIN FAMILY 1D SECRETOGLOBIN FAMILY 1D MEMBER 1 transfer/carrier protein#PC00219 HUMAN|HGNC=2646|UniProtKB=Q08477 Q08477 CYP4F3 PTHR24291:SF170 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497 long-chain fatty acid metabolic process#GO:0001676;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid derivative metabolic process#GO:1901568;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 oxygenase#PC00177 HUMAN|HGNC=18789|UniProtKB=Q9Y247 Q9Y247 FAM50B PTHR12722:SF1 XAP-5 PROTEIN-RELATED PROTEIN FAM50B cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=30809|UniProtKB=Q92519 Q92519 TRIB2 PTHR22961:SF15 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 2 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;regulation of intracellular signal transduction#GO:1902531;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;intracellular signal transduction#GO:0035556;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;positive regulation of proteasomal protein catabolic process#GO:1901800;organonitrogen compound catabolic process#GO:1901565;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;catabolic process#GO:0009056;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;signaling#GO:0023052;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of transferase activity#GO:0051338;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=12205|UniProtKB=A0A075B6N4 A0A075B6N4 TRBV25-1 PTHR23268:SF30 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 25-1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=9583|UniProtKB=P26599 P26599 PTBP1 PTHR15592:SF19 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 1 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;RNA splicing#GO:0008380;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;RNA processing#GO:0006396;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;translation#GO:0006412;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=17031|UniProtKB=Q8WTQ7 Q8WTQ7 GRK7 PTHR24355:SF12 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RHODOPSIN KINASE GRK7 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 HUMAN|HGNC=23436|UniProtKB=B3EWG3 B3EWG3 FAM25A PTHR34994:SF1 PROTEIN FAM25A-RELATED PROTEIN FAM25A-RELATED HUMAN|HGNC=25440|UniProtKB=Q8N394 Q8N394 TMTC2 PTHR44216:SF3 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 protein modifying enzyme#PC00260 HUMAN|HGNC=11015|UniProtKB=O14863 O14863 SLC30A4 PTHR11562:SF27 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER ZINC TRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;response to inorganic substance#GO:0010035;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;homeostatic process#GO:0042592;response to metal ion#GO:0010038;cation homeostasis#GO:0055080;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=15679|UniProtKB=Q8WZ74 Q8WZ74 CTTNBP2 PTHR24166:SF27 ROLLING PEBBLES, ISOFORM B CORTACTIN-BINDING PROTEIN 2 HUMAN|HGNC=3447|UniProtKB=P84090 P84090 ERH PTHR12373:SF9 ENHANCER OF RUDIMENTARY ERH ENHANCER OF RUDIMENTARY HOMOLOG DNA-binding transcription factor#PC00218 HUMAN|HGNC=483|UniProtKB=P03950 P03950 ANG PTHR11437:SF60 RIBONUCLEASE ANGIOGENIN catalytic activity, acting on RNA#GO:0140098;ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;humoral immune response#GO:0006959;developmental process#GO:0032502;antibacterial humoral response#GO:0019731;system development#GO:0048731;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;innate immune response#GO:0045087;vasculature development#GO:0001944;defense response#GO:0006952;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;multicellular organism development#GO:0007275;tube development#GO:0035295;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to Gram-positive bacterium#GO:0050830;anatomical structure formation involved in morphogenesis#GO:0048646;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;angiogenesis#GO:0001525;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 Angiogenesis#P00005>Ang-2#P00246 HUMAN|HGNC=19654|UniProtKB=Q7RTT4 Q7RTT4 SSX8P PTHR14112:SF27 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX6-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=3242|UniProtKB=Q9H4M9 Q9H4M9 EHD1 PTHR11216:SF127 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 1 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 microtubule-based protein transport#GO:0099118;endosomal transport#GO:0016197;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;endocytic recycling#GO:0032456;membrane invagination#GO:0010324;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;protein localization to plasma membrane#GO:0072659;vesicle localization#GO:0051648;protein localization to membrane#GO:0072657;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;protein localization to cell periphery#GO:1990778;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;perinuclear region of cytoplasm#GO:0048471;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=9033|UniProtKB=Q9UNK4 Q9UNK4 PLA2G2D PTHR11716:SF57 PHOSPHOLIPASE A2 FAMILY MEMBER GROUP IID SECRETORY PHOSPHOLIPASE A2 cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipase activity#GO:0004620;anion binding#GO:0043168;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;phospholipid metabolic process#GO:0006644;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;phosphorus metabolic process#GO:0006793;leukocyte cell-cell adhesion#GO:0007159;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;T cell proliferation#GO:0042098;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;negative regulation of cell population proliferation#GO:0008285;regulation of cell adhesion#GO:0030155;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;metabolic process#GO:0008152;negative regulation of T cell proliferation#GO:0042130;lymphocyte activation#GO:0046649;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;cellular metabolic process#GO:0044237;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cell adhesion#GO:0007155;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;primary metabolic process#GO:0044238;regulation of T cell proliferation#GO:0042129;negative regulation of cell adhesion#GO:0007162;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;negative regulation of immune system process#GO:0002683;organophosphate metabolic process#GO:0019637;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;cellular lipid metabolic process#GO:0044255 phospholipase#PC00186 HUMAN|HGNC=29081|UniProtKB=Q4V321 Q4V321 GAGE13 PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=25695|UniProtKB=Q9HA77 Q9HA77 CARS2 PTHR10890:SF27 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on RNA#GO:0140098;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;ligase activity#GO:0016874;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a tRNA#GO:0140101;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=5857|UniProtKB=P0DOY3 P0DOY3 IGLC3 PTHR23266:SF283 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA CONSTANT 2-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=25928|UniProtKB=Q6P4I2 Q6P4I2 WDR73 PTHR46947:SF1 WD REPEAT-CONTAINING PROTEIN 73 WD REPEAT-CONTAINING PROTEIN 73 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;spindle pole#GO:0000922;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819 HUMAN|HGNC=3372|UniProtKB=O95936 O95936 EOMES PTHR11267:SF13 T-BOX PROTEIN-RELATED EOMESODERMIN HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 specification of symmetry#GO:0009799;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;ectoderm formation#GO:0001705;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;heart looping#GO:0001947;mesoderm morphogenesis#GO:0048332;leukocyte activation#GO:0045321;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;ectoderm development#GO:0007398;alpha-beta T cell differentiation#GO:0046632;cellular developmental process#GO:0048869;lymphocyte activation involved in immune response#GO:0002285;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;cell fate commitment#GO:0045165;cell activation involved in immune response#GO:0002263;T cell differentiation#GO:0030217;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cell activation#GO:0001775;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;heart development#GO:0007507;embryonic heart tube development#GO:0035050;determination of heart left/right asymmetry#GO:0061371;RNA metabolic process#GO:0016070;mesoderm formation#GO:0001707;epithelium development#GO:0060429;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;determination of bilateral symmetry#GO:0009855;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;system development#GO:0048731;endoderm formation#GO:0001706;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;determination of left/right symmetry#GO:0007368;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;immune effector process#GO:0002252;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;lymphocyte activation#GO:0046649;immune response#GO:0006955;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;mesoderm development#GO:0007498;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;lymphocyte differentiation#GO:0030098;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;T cell activation#GO:0042110;regulation of nucleobase-containing compound metabolic process#GO:0019219;formation of primary germ layer#GO:0001704;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=1367|UniProtKB=Q96E40 Q96E40 SPACA9 PTHR32455:SF1 SPERM ACROSOME-ASSOCIATED PROTEIN 9 SPERM ACROSOME-ASSOCIATED PROTEIN 9 supramolecular complex#GO:0099080;axoneme#GO:0005930;acrosomal vesicle#GO:0001669;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;ciliary base#GO:0097546;secretory granule#GO:0030141;vacuole#GO:0005773;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;ciliary transition fiber#GO:0097539;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;C2 axonemal microtubule#GO:1990720;B axonemal microtubule#GO:0097650;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;intracellular vesicle#GO:0097708;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;ciliary transition zone#GO:0035869;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503;plasma membrane#GO:0005886;axonemal microtubule#GO:0005879 HUMAN|HGNC=21186|UniProtKB=Q5SQI0 Q5SQI0 ATAT1 PTHR12327:SF0 UNCHARACTERIZED ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 peptidyl-lysine modification#GO:0018205;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein acetylation#GO:0006473;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475;metabolic process#GO:0008152 HUMAN|HGNC=28343|UniProtKB=Q8TCB7 Q8TCB7 METTL6 PTHR22809:SF5 METHYLTRANSFERASE-RELATED TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL6 methyltransferase#PC00155 HUMAN|HGNC=33203|UniProtKB=A8MWA4 A8MWA4 ZNF705E PTHR24381:SF312 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 705E-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20509|UniProtKB=Q6PJT7 Q6PJT7 ZC3H14 PTHR14738:SF29 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;negative regulation of RNA metabolic process#GO:0051253;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;mRNA 3'-end processing#GO:0031124;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of mRNA processing#GO:0050684;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA polyadenylation#GO:0006378;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;mRNA processing#GO:0006397;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=10646|UniProtKB=Q9UBD3 Q9UBD3 XCL2 PTHR12015:SF101 SMALL INDUCIBLE CYTOKINE A CYTOKINE SCM-1 BETA-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=25978|UniProtKB=Q9NXI6 Q9NXI6 RNF186 PTHR16450:SF1 RING FINGER PROTEIN 186 E3 UBIQUITIN-PROTEIN LIGASE RNF186 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 HUMAN|HGNC=29571|UniProtKB=Q969E1 Q969E1 LEAP2 PTHR21007:SF1 LIVER EXPRESSED ANTIMICROBIAL PEPTIDE 2 LIVER-EXPRESSED ANTIMICROBIAL PEPTIDE 2 HUMAN|HGNC=25843|UniProtKB=Q32MQ0 Q32MQ0 ZNF750 PTHR14678:SF1 UNCHARACTERIZED ZINC FINGER PROTEIN 750 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;epidermis development#GO:0008544;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26151|UniProtKB=Q9H6T3 Q9H6T3 RPAP3 PTHR46423:SF1 RNA POLYMERASE II-ASSOCIATED PROTEIN 3 RNA POLYMERASE II-ASSOCIATED PROTEIN 3 HUMAN|HGNC=28787|UniProtKB=Q969X0 Q969X0 RILPL2 PTHR21502:SF2 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN 2 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=14436|UniProtKB=Q70E73 Q70E73 RAPH1 PTHR11243:SF15 GROWTH FACTOR RECEPTOR-BOUND PROTEIN RAS-ASSOCIATED AND PLECKSTRIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=14661|UniProtKB=Q9H6Z9 Q9H6Z9 EGLN3 PTHR12907:SF5 EGL NINE HOMOLOG-RELATED PROLYL HYDROXYLASE EGLN3 cation binding#GO:0043169;ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;dioxygenase activity#GO:0051213;metal ion binding#GO:0046872;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;response to hypoxia#GO:0001666;cellular response to chemical stimulus#GO:0070887;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;response to decreased oxygen levels#GO:0036293;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular response to hypoxia#GO:0071456;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;response to abiotic stimulus#GO:0009628;cellular protein metabolic process#GO:0044267;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;response to oxygen levels#GO:0070482 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 HUMAN|HGNC=16183|UniProtKB=Q9H426 Q9H426 RIMS4 PTHR12157:SF17 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 4 Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;ion channel binding#GO:0044325;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rab GTPase binding#GO:0017137 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=15906|UniProtKB=A7E2Y1 A7E2Y1 MYH7B PTHR45615:SF29 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-7B Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=11995|UniProtKB=O14657 O14657 TOR1B PTHR10760:SF14 TORSIN TORSIN-1B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;nuclear envelope organization#GO:0006998 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=4320|UniProtKB=P10075 P10075 GLI4 PTHR24388:SF50 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 281-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6400|UniProtKB=Q14974 Q14974 KPNB1 PTHR10527:SF1 IMPORTIN BETA IMPORTIN SUBUNIT BETA-1 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=7398|UniProtKB=P04733 P04733 MT1F PTHR23299:SF55 METALLOTHIONEIN METALLOTHIONEIN-1F cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;transition metal ion homeostasis#GO:0055076;response to metal ion#GO:0010038;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;response to toxic substance#GO:0009636;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6000|UniProtKB=P18510 P18510 IL1RN PTHR10078:SF28 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to lipopolysaccharide#GO:0071222;gene expression#GO:0010467;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of metabolic process#GO:0009893;response to biotic stimulus#GO:0009607;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 interleukin superfamily#PC00128 HUMAN|HGNC=25287|UniProtKB=Q68DH5 Q68DH5 LMBRD2 PTHR21355:SF0 UNCHARACTERIZED G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=4936|UniProtKB=P06340 P06340 HLA-DOA PTHR19944:SF44 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DO ALPHA CHAIN major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 HUMAN|HGNC=8318|UniProtKB=Q9UKL2 Q9UKL2 OR52A1 PTHR26450:SF98 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52A1 transmembrane signal receptor#PC00197 HUMAN|HGNC=2227|UniProtKB=P49747 P49747 COMP PTHR10199:SF88 THROMBOSPONDIN CARTILAGE OLIGOMERIC MATRIX PROTEIN extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=28323|UniProtKB=Q96C00 Q96C00 ZBTB9 PTHR24414:SF24 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 9 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=4646|UniProtKB=P52655 P52655 GTF2A1 PTHR12694:SF7 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 HUMAN|HGNC=4702|UniProtKB=P02724 P02724 GYPA PTHR13813:SF3 GLYCOPHORIN GLYCOPHORIN-A intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=8940|UniProtKB=O14832 O14832 PHYH PTHR21308:SF1 PHYTANOYL-COA ALPHA-HYDROXYLASE PHYTANOYL-COA DIOXYGENASE, PEROXISOMAL hydroxylase#PC00122 HUMAN|HGNC=8657|UniProtKB=Q9NPG4 Q9NPG4 PCDH12 PTHR24028:SF42 CADHERIN-87A PROTOCADHERIN-12 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=11701|UniProtKB=P13385 P13385 TDGF1 PTHR14949:SF26 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 TERATOCARCINOMA-DERIVED GROWTH FACTOR 1 protein binding#GO:0005515;binding#GO:0005488;receptor serine/threonine kinase binding#GO:0033612;signaling receptor binding#GO:0005102 specification of symmetry#GO:0009799;cellular response to stimulus#GO:0051716;heart development#GO:0007507;signal transduction#GO:0007165;circulatory system development#GO:0072359;enzyme linked receptor protein signaling pathway#GO:0007167;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;determination of bilateral symmetry#GO:0009855;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;determination of left/right symmetry#GO:0007368;pattern specification process#GO:0007389;signaling#GO:0023052 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=13759|UniProtKB=Q7L576 Q7L576 CYFIP1 PTHR12195:SF0 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell morphogenesis#GO:0000902;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 HUMAN|HGNC=28612|UniProtKB=P0CG35 P0CG35 TMSB15B PTHR12021:SF11 THYMOSIN BETA THYMOSIN BETA-15A-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;cellular protein localization#GO:0034613;protein-containing complex assembly#GO:0065003;regulation of localization#GO:0032879;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;regulation of cellular component movement#GO:0051270;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of cell motility#GO:2000145;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;localization of cell#GO:0051674;actin polymerization or depolymerization#GO:0008154;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=38688|UniProtKB=P0CJ86 P0CJ86 DUX4L3 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=4237|UniProtKB=Q99684 Q99684 GFI1 PTHR24404:SF46 ZINC FINGER PROTEIN ZINC FINGER PROTEIN GFI-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28044|UniProtKB=A8MV81 A8MV81 HIGD1C PTHR12297:SF10 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1C cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11025|UniProtKB=Q07837 Q07837 SLC3A1 PTHR10357:SF179 ALPHA-AMYLASE FAMILY MEMBER NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 amylase#PC00048 HUMAN|HGNC=23059|UniProtKB=Q96GW7 Q96GW7 BCAN PTHR22804:SF41 AGGRECAN/VERSICAN PROTEOGLYCAN BREVICAN CORE PROTEIN extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=31928|UniProtKB=Q6ZNJ1 Q6ZNJ1 NBEAL2 PTHR13743:SF111 BEIGE/BEACH-RELATED NEUROBEACHIN-LIKE PROTEIN 2 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 localization#GO:0051179;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=23035|UniProtKB=Q96JM7 Q96JM7 L3MBTL3 PTHR12247:SF72 POLYCOMB GROUP PROTEIN LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN 3 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=24542|UniProtKB=Q9BVM2 Q9BVM2 DPCD PTHR31921:SF1 PROTEIN DPCD PROTEIN DPCD HUMAN|HGNC=24642|UniProtKB=Q9H1Z8 Q9H1Z8 ECRG4 PTHR31613:SF2 AUGURIN AUGURIN cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;cell cycle process#GO:0022402;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;cell population proliferation#GO:0008283;nervous system development#GO:0007399;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;central nervous system development#GO:0007417;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular developmental process#GO:0048869;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular protein catabolic process#GO:0044257;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=21259|UniProtKB=Q6IMN6 Q6IMN6 CAPRIN2 PTHR22922:SF5 GPI-ANCHORED PROTEIN P137 CAPRIN-2 RNA metabolism protein#PC00031 HUMAN|HGNC=1477|UniProtKB=Q9HC96 Q9HC96 CAPN10 PTHR10183:SF30 CALPAIN CALPAIN-10 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=30483|UniProtKB=Q96MG8 Q96MG8 PCMTD1 PTHR11579:SF4 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 methyltransferase#PC00155 HUMAN|HGNC=11876|UniProtKB=O15393 O15393 TMPRSS2 PTHR24253:SF89 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 2 serine protease#PC00203 HUMAN|HGNC=22967|UniProtKB=P60368 P60368 KRTAP10-2 PTHR23262:SF8 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-2 HUMAN|HGNC=23803|UniProtKB=Q6IQ32 Q6IQ32 ADNP2 PTHR15740:SF2 NEUROPROTECTIVE PEPTIDE-CONTAINING PROTEIN ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN 2 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=7701|UniProtKB=O95139 O95139 NDUFB6 PTHR15083:SF0 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 dehydrogenase#PC00092 HUMAN|HGNC=18183|UniProtKB=Q8TF64 Q8TF64 GIPC3 PTHR12259:SF2 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC3 scaffold/adaptor protein#PC00226 HUMAN|HGNC=13261|UniProtKB=Q5W186 Q5W186 CST9 PTHR46945:SF4 CYSTATIN-9-LIKE CYSTATIN-9 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=11257|UniProtKB=P35270 P35270 SPR PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;pteridine-containing compound metabolic process#GO:0042558;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704 reductase#PC00198 HUMAN|HGNC=29210|UniProtKB=Q8N344 Q8N344 MIER2 PTHR10865:SF27 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN MESODERM INDUCTION EARLY RESPONSE PROTEIN 2 repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 HUMAN|Ensembl=ENSG00000283697|UniProtKB=A0A1B0GWH4 A0A1B0GWH4 HSFX3 PTHR10015:SF140 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK TRANSCRIPTION FACTOR, X-LINKED MEMBER 3-RELATED winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=11997|UniProtKB=Q9H497 Q9H497 TOR3A PTHR10760:SF3 TORSIN TORSIN-3A pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=24683|UniProtKB=Q969F0 Q969F0 FATE1 PTHR21128:SF0 FETAL AND ADULT TESTIS-EXPRESSED TRANSCRIPT PROTEIN FETAL AND ADULT TESTIS-EXPRESSED TRANSCRIPT PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;cell death#GO:0008219;cellular divalent inorganic cation homeostasis#GO:0072503;mitochondrial calcium ion homeostasis#GO:0051560;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;cellular cation homeostasis#GO:0030003;regulation of apoptotic process#GO:0042981;homeostatic process#GO:0042592;programmed cell death#GO:0012501;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;negative regulation of apoptotic process#GO:0043066;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;regulation of cell death#GO:0010941;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;vacuole#GO:0005773;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;mitochondria-associated endoplasmic reticulum membrane#GO:0044233;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;outer membrane#GO:0019867;plasma membrane#GO:0005886 HUMAN|HGNC=13233|UniProtKB=P39687 P39687 ANP32A PTHR11375:SF1 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=2068|UniProtKB=P49759 P49759 CLK1 PTHR45646:SF4 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK1 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=6494|UniProtKB=Q9Y6N6 Q9Y6N6 LAMC3 PTHR10574:SF240 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-3 system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;tissue development#GO:0009888 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=16283|UniProtKB=Q14142 Q14142 TRIM14 PTHR24103:SF595 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 14 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=1137|UniProtKB=Q8WVV5 Q8WVV5 BTN2A2 PTHR24100:SF120 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 2 MEMBER A2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=22831|UniProtKB=A6NCM1 A6NCM1 IQCA1L PTHR14690:SF6 UNCHARACTERIZED IQ AND AAA DOMAIN-CONTAINING PROTEIN 1-LIKE HUMAN|HGNC=12957|UniProtKB=Q14929 Q14929 ZNF169 PTHR24381:SF25 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 169 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=16504|UniProtKB=Q8NFQ5 Q8NFQ5 BPIFB6 PTHR46019:SF2 BPI FOLD-CONTAINING FAMILY B MEMBER 4-RELATED BPI FOLD-CONTAINING FAMILY B MEMBER 6 HUMAN|HGNC=32954|UniProtKB=Q5I0X7 Q5I0X7 TTC32 PTHR47059:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 32 TETRATRICOPEPTIDE REPEAT PROTEIN 32 HUMAN|HGNC=18413|UniProtKB=Q8IUH4 Q8IUH4 ZDHHC13 PTHR24161:SF16 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED IQ MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1-RELATED transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=28283|UniProtKB=Q6UXU4 Q6UXU4 GSG1L PTHR10671:SF35 EPITHELIAL MEMBRANE PROTEIN-RELATED GERM CELL-SPECIFIC GENE 1-LIKE PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=28636|UniProtKB=Q9BPU9 Q9BPU9 B9D2 PTHR12968:SF2 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 2 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 structural protein#PC00211 HUMAN|HGNC=16101|UniProtKB=Q5JX69 Q5JX69 FAM209B PTHR35157:SF4 PROTEIN FAM209A PROTEIN FAM209B HUMAN|HGNC=5045|UniProtKB=P14866 P14866 HNRNPL PTHR15592:SF20 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16198|UniProtKB=Q9H1H1 Q9H1H1 GTSF1L PTHR21402:SF3 UNCHARACTERIZED GAMETOCYTE-SPECIFIC FACTOR 1-LIKE HUMAN|HGNC=12668|UniProtKB=O14598 O14598 VCY PTHR15251:SF2 TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED HUMAN|HGNC=8082|UniProtKB=Q9GZU5 Q9GZU5 NYX PTHR24373:SF264 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN NYCTALOPIN extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=2288|UniProtKB=P14406 P14406 COX7A2 PTHR10510:SF15 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A2, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular component biogenesis#GO:0044085;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;protein-containing complex subunit organization#GO:0043933;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;regulation of phosphorylation#GO:0042325;nucleoside phosphate biosynthetic process#GO:1901293;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;regulation of phosphate metabolic process#GO:0019220;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;organelle organization#GO:0006996;oxidative phosphorylation#GO:0006119;biological regulation#GO:0065007;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227 oxidase#PC00175 HUMAN|HGNC=12771|UniProtKB=O95389 O95389 CCN6 PTHR11348:SF3 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CELLULAR COMMUNICATION NETWORK FACTOR 6 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;biological adhesion#GO:0022610;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;regulation of cell death#GO:0010941;cell death#GO:0008219;biological regulation#GO:0065007;signaling#GO:0023052;negative regulation of cellular process#GO:0048523 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=2361|UniProtKB=P52943 P52943 CRIP2 PTHR46074:SF2 CYSTEINE-RICH PROTEIN CRIP FAMILY MEMBER CYSTEINE-RICH PROTEIN 2 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=5448|UniProtKB=P05000 P05000 IFNW1 PTHR11691:SF37 TYPE I INTERFERON INTERFERON OMEGA-1 interferon superfamily#PC00127 HUMAN|HGNC=25762|UniProtKB=Q969V5 Q969V5 MUL1 PTHR12183:SF4 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12582|UniProtKB=P14927 P14927 UQCRB PTHR12022:SF5 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 7 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular component biogenesis#GO:0044085;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cytochrome complex assembly#GO:0017004;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;protein-containing complex subunit organization#GO:0043933;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex III assembly#GO:0034551;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;mitochondrial respiratory chain complex assembly#GO:0033108;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;metabolic process#GO:0008152;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;organelle organization#GO:0006996;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respiratory chain complex III#GO:0005750;membrane-bounded organelle#GO:0043227 reductase#PC00198 HUMAN|HGNC=27329|UniProtKB=Q9Y3T6 Q9Y3T6 R3HCC1 PTHR21678:SF6 GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88 R3H AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=1008|UniProtKB=O00512 O00512 BCL9 PTHR15185:SF5 BCL9 B-CELL CLL/LYMPHOMA 9 PROTEIN protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 Wnt signaling pathway#P00057>Bcl9#P01450 HUMAN|HGNC=24561|UniProtKB=Q68CL5 Q68CL5 TPGS2 PTHR31854:SF2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=13479|UniProtKB=Q9BY64 Q9BY64 UGT2B28 PTHR48043:SF86 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2B10-RELATED transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=2739|UniProtKB=O60231 O60231 DHX16 PTHR18934:SF83 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16 RNA helicase#PC00032 HUMAN|HGNC=1749|UniProtKB=Q9Y6N8 Q9Y6N8 CDH10 PTHR24027:SF290 CADHERIN-23 CADHERIN-10 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=27845|UniProtKB=Q5JUK2 Q5JUK2 SOHLH1 PTHR16223:SF14 TRANSCRIPTION FACTOR BHLH83-RELATED SPERMATOGENESIS- AND OOGENESIS-SPECIFIC BASIC HELIX-LOOP-HELIX-CONTAINING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=34339|UniProtKB=Q3ZCQ3 Q3ZCQ3 FAM174B PTHR28607:SF3 EXPRESSED PROTEIN MEMBRANE PROTEIN FAM174B HUMAN|HGNC=144|UniProtKB=P63261 P63261 ACTG1 PTHR11937:SF414 ACTIN ACTIN, CYTOPLASMIC 2 actin and actin related protein#PC00039 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 HUMAN|HGNC=6343|UniProtKB=P21583 P21583 KITLG PTHR11574:SF0 KIT LIGAND KIT LIGAND binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=19736|UniProtKB=A6NMN3 A6NMN3 FAM170B PTHR33517:SF2 PROTEIN FAM170B-RELATED PROTEIN FAM170B HUMAN|HGNC=24721|UniProtKB=Q9H6S0 Q9H6S0 YTHDC2 PTHR18934:SF100 ATP-DEPENDENT RNA HELICASE 3'-5' RNA HELICASE YTHDC2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA helicase#PC00032 HUMAN|HGNC=950|UniProtKB=Q92560 Q92560 BAP1 PTHR10589:SF28 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE BAP1 hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=17597|UniProtKB=Q9UBB6 Q9UBB6 NCDN PTHR13109:SF7 NEUROCHONDRIN NEUROCHONDRIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=25632|UniProtKB=Q9BRF8 Q9BRF8 CPPED1 PTHR43143:SF1 METALLOPHOSPHOESTERASE, CALCINEURIN SUPERFAMILY SERINE/THREONINE-PROTEIN PHOSPHATASE CPPED1 HUMAN|HGNC=23789|UniProtKB=Q9BW66 Q9BW66 CINP PTHR15827:SF2 CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN Cell cycle#P00013>Cdk2#P00485 HUMAN|HGNC=2654|UniProtKB=O00622 O00622 CCN1 PTHR11348:SF18 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 1 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;biological adhesion#GO:0022610;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;regulation of cell death#GO:0010941;cell death#GO:0008219;biological regulation#GO:0065007;signaling#GO:0023052;negative regulation of cellular process#GO:0048523 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=34393|UniProtKB=A3QJZ6 A3QJZ6 PRAMEF22 PTHR14224:SF79 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 18-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2936|UniProtKB=Q09019 Q09019 DMWD PTHR14107:SF15 WD REPEAT PROTEIN DYSTROPHIA MYOTONICA WD REPEAT-CONTAINING PROTEIN HUMAN|HGNC=14723|UniProtKB=Q8NGS4 Q8NGS4 OR13F1 PTHR24248:SF82 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 13F1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=25164|UniProtKB=Q96EG3 Q96EG3 ZNF837 PTHR24377:SF624 IP01015P-RELATED ZINC FINGER PROTEIN 837 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12679|UniProtKB=P11473 P11473 VDR PTHR24082:SF38 NUCLEAR HORMONE RECEPTOR VITAMIN D3 RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 Vitamin D metabolism and pathway#P04396>VDR#P04606 HUMAN|HGNC=3618|UniProtKB=P31994 P31994 FCGR2B PTHR11481:SF104 IMMUNOGLOBULIN FC RECEPTOR LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR II-B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=8547|UniProtKB=O15460 O15460 P4HA2 PTHR10869:SF176 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=2623|UniProtKB=P11712 P11712 CYP2C9 PTHR24300:SF336 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C9 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=17661|UniProtKB=Q53H76 Q53H76 PLA1A PTHR11610:SF111 LIPASE PHOSPHOLIPASE A1 MEMBER A hydrolase activity#GO:0016787;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;lipid catabolic process#GO:0016042;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 lipase#PC00143 2-arachidonoylglycerol biosynthesis#P05726>PLA1#P05735 HUMAN|HGNC=12121|UniProtKB=A0A0B4J272 A0A0B4J272 TRAV24 PTHR19433:SF123 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 24 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=5593|UniProtKB=P0DP02 P0DP02 IGHV3-30-3 PTHR23266:SF241 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=30547|UniProtKB=Q96K17 Q96K17 BTF3L4 PTHR10351:SF29 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 HOMOLOG 4 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosol#GO:0005829;polysome#GO:0005844;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=24271|UniProtKB=Q9NTM9 Q9NTM9 CUTC PTHR12598:SF0 COPPER HOMEOSTASIS PROTEIN CUTC COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG cation binding#GO:0043169;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;transition metal ion binding#GO:0046914 inorganic ion homeostasis#GO:0098771;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;transition metal ion homeostasis#GO:0055076;biological regulation#GO:0065007;homeostatic process#GO:0042592;copper ion homeostasis#GO:0055070;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;metal ion homeostasis#GO:0055065 primary active transporter#PC00068 HUMAN|HGNC=18197|UniProtKB=Q05BV3 Q05BV3 EML5 PTHR13720:SF16 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 5 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 HUMAN|HGNC=3016|UniProtKB=O14531 O14531 DPYSL4 PTHR11647:SF55 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 4 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339 HUMAN|HGNC=38606|UniProtKB=A8MW95 A8MW95 BECN2 PTHR12768:SF5 BECLIN 1 BECLIN-2 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;protein targeting to vacuole#GO:0006623;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;late endosome to vacuole transport#GO:0045324;response to extracellular stimulus#GO:0009991;establishment of protein localization#GO:0045184;vacuole organization#GO:0007033;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;establishment of protein localization to vacuole#GO:0072666;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;protein maturation#GO:0051604;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;protein transport#GO:0015031;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;autophagy#GO:0006914;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein processing#GO:0016485;process utilizing autophagic mechanism#GO:0061919;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular response to starvation#GO:0009267;vacuolar protein processing#GO:0006624;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular response to stimulus#GO:0051716;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle assembly#GO:0070925;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cellular response to nutrient levels#GO:0031669;organelle organization#GO:0006996;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;intracellular#GO:0005622;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;phosphatidylinositol 3-kinase complex, class III#GO:0035032;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 protease inhibitor#PC00191 HUMAN|HGNC=33132|UniProtKB=Q5NE16 Q5NE16 CTSL3P PTHR12411:SF840 CYSTEINE PROTEASE FAMILY C1-RELATED DIPEPTIDYL PEPTIDASE 1-RELATED cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=50800|UniProtKB=Q9UBX2 Q9UBX2 DUX4 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=20766|UniProtKB=Q71U36 Q71U36 TUBA1A PTHR11588:SF133 TUBULIN TUBULIN ALPHA-1A CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Gonadotropin-releasing hormone receptor pathway#P06664>Tubulin#P06772 HUMAN|HGNC=13531|UniProtKB=Q9Y2Q0 Q9Y2Q0 ATP8A1 PTHR24092:SF150 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IA pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=11149|UniProtKB=O75324 O75324 SNN PTHR28564:SF1 STANNIN STANNIN intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=33849|UniProtKB=Q6UXF7 Q6UXF7 CLEC18B PTHR10334:SF521 CYSTEINE-RICH SECRETORY PROTEIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 18 MEMBER A-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=15966|UniProtKB=Q86SG3 Q86SG3 DAZ4 PTHR11176:SF8 BOULE-RELATED DELETED IN AZOOSPERMIA PROTEIN 1-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of translational initiation#GO:0045948;gene expression#GO:0010467;regulation of translational initiation#GO:0006446;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;translational initiation#GO:0006413;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=22226|UniProtKB=Q96JH8 Q96JH8 RADIL PTHR16027:SF3 DILUTE DOMAIN-CONTAINING PROTEIN YPR089W RAS-ASSOCIATING AND DILUTE DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=17958|UniProtKB=Q6SPF0 Q6SPF0 SAMD1 PTHR12247:SF99 POLYCOMB GROUP PROTEIN ATHERIN-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=7218|UniProtKB=P05164 P05164 MPO PTHR11475:SF108 OXIDASE/PEROXIDASE MYELOPEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180 HUMAN|HGNC=3258|UniProtKB=P49770 P49770 EIF2B2 PTHR45859:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;guanyl-nucleotide exchange factor activity#GO:0005085 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;regulation of translational initiation#GO:0006446;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;translational initiation#GO:0006413;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=11427|UniProtKB=Q9UNE7 Q9UNE7 STUB1 PTHR46803:SF2 E3 UBIQUITIN-PROTEIN LIGASE CHIP E3 UBIQUITIN-PROTEIN LIGASE CHIP transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;chaperone binding#GO:0051087 regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular response to misfolded protein#GO:0071218;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>CHIP#P01214 HUMAN|HGNC=3749|UniProtKB=Q01543 Q01543 FLI1 PTHR11849:SF161 ETS FRIEND LEUKEMIA INTEGRATION 1 TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=1643|UniProtKB=P20273 P20273 CD22 PTHR46958:SF1 B-CELL RECEPTOR CD22 B-CELL RECEPTOR CD22 B cell activation#P00010>CD22#P00387 HUMAN|HGNC=20726|UniProtKB=Q8WVM8 Q8WVM8 SCFD1 PTHR11679:SF2 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 1 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Munc18#P05770 HUMAN|HGNC=5281|UniProtKB=P32314 P32314 FOXN2 PTHR13962:SF19 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N2 HUMAN|HGNC=6442|UniProtKB=P13647 P13647 KRT5 PTHR45616:SF32 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 5 HUMAN|HGNC=30009|UniProtKB=Q9UBV8 Q9UBV8 PEF1 PTHR46212:SF6 PEFLIN PEFLIN vesicle targeting, to, from or within Golgi#GO:0048199;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;Golgi vesicle budding#GO:0048194;membrane organization#GO:0061024;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;COPII-coated vesicle budding#GO:0090114;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933 HUMAN|HGNC=26253|UniProtKB=Q5SVZ6 Q5SVZ6 ZMYM1 PTHR45736:SF4 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 1 zinc finger transcription factor#PC00244 HUMAN|HGNC=166|UniProtKB=O43707 O43707 ACTN4 PTHR11915:SF425 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-4 Integrin signalling pathway#P00034>alpha actinin#P00928 HUMAN|HGNC=21496|UniProtKB=P53367 P53367 ARFIP1 PTHR12141:SF4 ARFAPTIN-RELATED ARFAPTIN-1 lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;positive regulation of supramolecular fiber organization#GO:1902905;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;peptide transport#GO:0015833;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein transport#GO:0015031;intracellular transport#GO:0046907;macromolecule localization#GO:0033036;positive regulation of organelle organization#GO:0010638;cellular protein localization#GO:0034613;positive regulation of actin filament polymerization#GO:0030838;transport#GO:0006810;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of protein-containing complex assembly#GO:0043254;supramolecular fiber organization#GO:0097435;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;positive regulation of protein-containing complex assembly#GO:0031334;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=14044|UniProtKB=Q4U2R6 Q4U2R6 MRPL51 PTHR13409:SF1 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L51 39S RIBOSOMAL PROTEIN L51, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=19743|UniProtKB=Q9UKY4 Q9UKY4 POMT2 PTHR10050:SF46 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 2 transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;cellular response to misfolded protein#GO:0071218;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;mannosylation#GO:0097502;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to endoplasmic reticulum stress#GO:0034976;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;cellular response to organic substance#GO:0071310;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;response to topologically incorrect protein#GO:0035966;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;glycosylation#GO:0070085 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=3496|UniProtKB=O60487 O60487 MPZL2 PTHR13869:SF21 MYELIN P0 RELATED MYELIN PROTEIN ZERO-LIKE PROTEIN 2 myelin protein#PC00161 HUMAN|HGNC=30897|UniProtKB=Q96JH7 Q96JH7 VCPIP1 PTHR14843:SF2 DEUBIQUITINATING PROTEIN VCIP135 DEUBIQUITINATING PROTEIN VCIP135 thiol-dependent ubiquitin-specific protease activity#GO:0004843;hydrolase activity#GO:0016787;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;Golgi organization#GO:0007030;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;membrane organization#GO:0061024;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein K48-linked deubiquitination#GO:0071108;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organelle fusion#GO:0048284;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081 HUMAN|HGNC=18017|UniProtKB=Q12769 Q12769 NUP160 PTHR21286:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP160 NUCLEAR PORE COMPLEX PROTEIN NUP160 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=2674|UniProtKB=P53355 P53355 DAPK1 PTHR24342:SF17 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;intracellular signal transduction#GO:0035556;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=18533|UniProtKB=Q86UV5 Q86UV5 USP48 PTHR24006:SF722 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 48 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=1060|UniProtKB=P32302 P32302 CXCR5 PTHR10489:SF618 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 5 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=18261|UniProtKB=Q8TAT6 Q8TAT6 NPLOC4 PTHR12710:SF0 NUCLEAR PROTEIN LOCALIZATION 4 NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8049|UniProtKB=P50583 P50583 NUDT2 PTHR21340:SF0 DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL] pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleotide diphosphatase activity#GO:0004551;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;ATP biosynthetic process#GO:0006754;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;purine nucleoside triphosphate biosynthetic process#GO:0009145;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;purine ribonucleoside triphosphate metabolic process#GO:0009205;AMP metabolic process#GO:0046033;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ribonucleoside triphosphate biosynthetic process#GO:0009201;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 hydrolase#PC00121 HUMAN|HGNC=28233|UniProtKB=Q6AI12 Q6AI12 ANKRD40 PTHR24192:SF1 ANKYRIN REPEAT DOMAIN 40 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 40 HUMAN|HGNC=7220|UniProtKB=Q14168 Q14168 MPP2 PTHR23122:SF35 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3600|UniProtKB=P23142 P23142 FBLN1 PTHR24050:SF23 PA14 DOMAIN-CONTAINING PROTEIN FIBULIN-1 HUMAN|HGNC=24945|UniProtKB=Q8IV16 Q8IV16 GPIHBP1 PTHR16983:SF12 UPAR/LY6 DOMAIN-CONTAINING PROTEIN GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED HIGH DENSITY LIPOPROTEIN-BINDING PROTEIN 1 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;receptor regulator activity#GO:0030545;acetylcholine receptor activity#GO:0015464;molecular function regulator#GO:0098772;molecular transducer activity#GO:0060089;acetylcholine receptor regulator activity#GO:0030548;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;acetylcholine binding#GO:0042166;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 HUMAN|HGNC=5291|UniProtKB=P28566 P28566 HTR1E PTHR24247:SF33 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1E cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;negative regulation of biological process#GO:0048519;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;negative regulation of intracellular signal transduction#GO:1902532;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;negative regulation of catalytic activity#GO:0043086;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935;negative regulation of molecular function#GO:0044092 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 HUMAN|HGNC=5784|UniProtKB=A2NJV5 A2NJV5 IGKV2-29 PTHR23267:SF278 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-29 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=26786|UniProtKB=Q8N8Y5 Q8N8Y5 ZFP41 PTHR24381:SF381 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 41 HOMOLOG DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=17050|UniProtKB=Q9UNX3 Q9UNX3 RPL26L1 PTHR11143:SF10 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER 60S RIBOSOMAL PROTEIN L26-LIKE 1 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=14631|UniProtKB=Q86TH1 Q86TH1 ADAMTSL2 PTHR13723:SF147 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 2 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=6347|UniProtKB=Q9Y5W3 Q9Y5W3 KLF2 PTHR23235:SF109 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23373|UniProtKB=Q9BV86 Q9BV86 NTMT1 PTHR12753:SF1 AD-003 - RELATED N-TERMINAL XAA-PRO-LYS N-METHYLTRANSFERASE 1 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein alkylation#GO:0008213;protein methylation#GO:0006479;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 methyltransferase#PC00155 HUMAN|HGNC=26239|UniProtKB=Q9H5V9 Q9H5V9 CXorf56 PTHR46355:SF1 UPF0428 PROTEIN CXORF56 UPF0428 PROTEIN CXORF56 HUMAN|HGNC=2586|UniProtKB=Q9UDT6 Q9UDT6 CLIP2 PTHR18916:SF10 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 chaperone#PC00072 HUMAN|HGNC=18402|UniProtKB=Q04323 Q04323 UBXN1 PTHR46340:SF1 UBX DOMAIN-CONTAINING PROTEIN 1 UBX DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=25340|UniProtKB=Q86V97 Q86V97 KBTBD6 PTHR24412:SF385 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 6 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28160|UniProtKB=Q2QGD7 Q2QGD7 ZXDC PTHR46179:SF5 ZINC FINGER PROTEIN ZINC FINGER PROTEIN ZXDC transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3031|UniProtKB=Q99856 Q99856 ARID3A PTHR15348:SF1 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=20517|UniProtKB=Q6DRA6 Q6DRA6 H2BC19P PTHR23428:SF298 HISTONE H2B HISTONE H2B TYPE 2-C-RELATED nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=7879|UniProtKB=O75175 O75175 CNOT3 PTHR23326:SF1 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;intracellular#GO:0005622;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 general transcription factor#PC00259 HUMAN|HGNC=29591|UniProtKB=O95561 O95561 C1orf105 PTHR39410:SF1 RIKEN CDNA 4930558K02 GENE RIKEN CDNA 4930558K02 GENE HUMAN|HGNC=22207|UniProtKB=Q9UPZ6 Q9UPZ6 THSD7A PTHR11311:SF8 SPONDIN THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 7A cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actin cytoskeleton reorganization#GO:0031532;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=31971|UniProtKB=O60810 O60810 PRAMEF4 PTHR14224:SF100 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 11-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=25721|UniProtKB=Q86VS3 Q86VS3 IQCH PTHR14465:SF0 IQ DOMAIN-CONTAINING PROTEIN H IQ DOMAIN-CONTAINING PROTEIN H HUMAN|HGNC=6740|UniProtKB=P61626 P61626 LYZ PTHR11407:SF28 LYSOZYME C LYSOZYME C hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;defense response to Gram-negative bacterium#GO:0050829;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830 HUMAN|HGNC=7583|UniProtKB=P10916 P10916 MYL2 PTHR23049:SF9 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2, VENTRICULAR/CARDIAC MUSCLE ISOFORM actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=2465|UniProtKB=O14594 O14594 NCAN PTHR22804:SF24 AGGRECAN/VERSICAN PROTEOGLYCAN NEUROCAN CORE PROTEIN extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=20220|UniProtKB=Q9Y324 Q9Y324 FCF1 PTHR12416:SF8 UNCHARACTERIZED RRNA-PROCESSING PROTEIN FCF1 HOMOLOG membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 HUMAN|HGNC=13875|UniProtKB=O15409 O15409 FOXP2 PTHR45796:SF8 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28751|UniProtKB=Q86Y78 Q86Y78 LYPD6 PTHR31171:SF0 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 6 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 6 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;receptor regulator activity#GO:0030545;binding#GO:0005488;acetylcholine receptor activity#GO:0015464;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;acetylcholine receptor regulator activity#GO:0030548;acetylcholine binding#GO:0042166;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of Wnt signaling pathway#GO:0030177;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 HUMAN|HGNC=485|UniProtKB=O15123 O15123 ANGPT2 PTHR19143:SF199 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-2 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;enzyme linked receptor protein signaling pathway#GO:0007167;developmental process#GO:0032502;multicellular organism development#GO:0007275;tube development#GO:0035295;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Angiogenesis#P00005>Ang-2#P00246 HUMAN|HGNC=30103|UniProtKB=Q14CZ0 Q14CZ0 C16orf72 PTHR31624:SF3 UPF0472 PROTEIN C16ORF72 UPF0472 PROTEIN C16ORF72 HUMAN|HGNC=30071|UniProtKB=Q8IZA0 Q8IZA0 KIAA0319L PTHR46182:SF3 FI19480P1 DYSLEXIA-ASSOCIATED PROTEIN KIAA0319-LIKE PROTEIN cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=6854|UniProtKB=Q9Y2U5 Q9Y2U5 MAP3K2 PTHR24361:SF342 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 2 Integrin signalling pathway#P00034>ERK#P00907;B cell activation#P00010>MEKK#P00369;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;PDGF signaling pathway#P00047>ERK#P01143;FGF signaling pathway#P00021>MEKK1-5#P00634;EGF receptor signaling pathway#P00018>MEKK1-5#P00553 HUMAN|HGNC=1027|UniProtKB=Q02338 Q02338 BDH1 PTHR43313:SF25 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C D-BETA-HYDROXYBUTYRATE DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092 HUMAN|HGNC=10062|UniProtKB=Q5VTR2 Q5VTR2 RNF20 PTHR23163:SF2 RING FINGER PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE BRE1A HUMAN|HGNC=30437|UniProtKB=Q6ICH7 Q6ICH7 ASPHD2 PTHR46332:SF3 ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 hydroxylase#PC00122 HUMAN|HGNC=1802|UniProtKB=Q15517 Q15517 CDSN PTHR23207:SF2 CORNEODESMOSIN CORNEODESMOSIN HUMAN|HGNC=18173|UniProtKB=Q9NZ08 Q9NZ08 ERAP1 PTHR11533:SF156 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1 cation binding#GO:0043169;metallopeptidase activity#GO:0008237;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;peptide binding#GO:0042277;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;peptidase activity#GO:0008233;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=33766|UniProtKB=Q6ZRC1 Q6ZRC1 C4orf50 PTHR36866:SF1 CHROMOSOME 4 OPEN READING FRAME 50 GENE 1043-RELATED HUMAN|HGNC=16632|UniProtKB=Q92665 Q92665 MRPS31 PTHR13231:SF3 MITOCHONDRIAL RIBOSOMAL PROTEIN S31 28S RIBOSOMAL PROTEIN S31, MITOCHONDRIAL ribosomal protein#PC00202 HUMAN|HGNC=19737|UniProtKB=Q63HR2 Q63HR2 TNS2 PTHR45734:SF1 TENSIN TENSIN-2 non-motor actin binding protein#PC00165 HUMAN|HGNC=13107|UniProtKB=P51814 P51814 ZNF41 PTHR24377:SF669 IP01015P-RELATED ZINC FINGER PROTEIN 41 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24640|UniProtKB=Q3B7T1 Q3B7T1 EDRF1 PTHR15000:SF1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=2527|UniProtKB=P07858 P07858 CTSB PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=11510|UniProtKB=Q8N9I0 Q8N9I0 SYT2 PTHR10024:SF223 SYNAPTOTAGMIN SYNAPTOTAGMIN-2 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;syntaxin binding#GO:0019905;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;synaptic signaling#GO:0099536;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;neurotransmitter secretion#GO:0007269;response to inorganic substance#GO:0010035;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;exocytic process#GO:0140029;cellular component organization or biogenesis#GO:0071840;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;regulation of neurotransmitter levels#GO:0001505;regulation of ion transport#GO:0043269;export from cell#GO:0140352;vesicle fusion#GO:0006906;regulation of signaling#GO:0023051;transport#GO:0006810;cation transport#GO:0006812;organic substance transport#GO:0071702;regulation of transport#GO:0051049;neurotransmitter transport#GO:0006836;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;response to metal ion#GO:0010038;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;response to chemical#GO:0042221;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 HUMAN|HGNC=26319|UniProtKB=Q96LT6 Q96LT6 C1orf74 PTHR31366:SF2 UPF0739 PROTEIN C1ORF74 UPF0739 PROTEIN C1ORF74 HUMAN|HGNC=4751|UniProtKB=P33778 P33778 H2BC3 PTHR23428:SF313 HISTONE H2B HISTONE H2B TYPE 1-B nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=7064|UniProtKB=O14880 O14880 MGST3 PTHR10250:SF22 MICROSOMAL GLUTATHIONE S-TRANSFERASE MICROSOMAL GLUTATHIONE S-TRANSFERASE 3 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=4249|UniProtKB=O95749 O95749 GGPS1 PTHR12001:SF44 GERANYLGERANYL PYROPHOSPHATE SYNTHASE GERANYLGERANYL PYROPHOSPHATE SYNTHASE Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 HUMAN|HGNC=10059|UniProtKB=O00635 O00635 TRIM38 PTHR24103:SF47 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM38 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;protein homodimerization activity#GO:0042803;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;identical protein binding#GO:0042802;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;kinase binding#GO:0019900 regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;aromatic compound biosynthetic process#GO:0019438;positive regulation of autophagy#GO:0010508;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=37116|UniProtKB=A6NP61 A6NP61 ZAR1L PTHR31054:SF5 ZYGOTE ARREST PROTEIN 1-LIKE ISOFORM X1 ZAR1-LIKE PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=7217|UniProtKB=P40238 P40238 MPL PTHR23037:SF31 CYTOKINE RECEPTOR THROMBOPOIETIN RECEPTOR transmembrane signal receptor#PC00197 HUMAN|HGNC=5648|UniProtKB=P0DP06 P0DP06 IGHV4-30-4 PTHR23266:SF323 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=3261|UniProtKB=Q13144 Q13144 EIF2B5 PTHR45887:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON nucleic acid binding#GO:0003676;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=19870|UniProtKB=Q7Z5H4 Q7Z5H4 VN1R5 PTHR24062:SF174 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 5-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=16979|UniProtKB=Q92496 Q92496 CFHR4 PTHR45785:SF4 COMPLEMENT FACTOR H-RELATED COMPLEMENT FACTOR H-RELATED PROTEIN 3-RELATED HUMAN|HGNC=30683|UniProtKB=Q9BX59 Q9BX59 TAPBPL PTHR23411:SF18 TAPASIN TAPASIN-RELATED PROTEIN immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=9204|UniProtKB=P27169 P27169 PON1 PTHR11799:SF16 PARAOXONASE SERUM PARAOXONASE/ARYLESTERASE 1 HUMAN|HGNC=27036|UniProtKB=Q86SE5 Q86SE5 RALYL PTHR13968:SF21 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING RALY-LIKE PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=18507|UniProtKB=Q96PJ5 Q96PJ5 FCRL4 PTHR11481:SF59 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=9849|UniProtKB=O14715 O14715 RGPD8 PTHR23138:SF87 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20342|UniProtKB=Q96MV8 Q96MV8 ZDHHC15 PTHR22883:SF270 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC15 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;developmental process#GO:0032502;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;vesicle organization#GO:0016050;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;cellular process#GO:0009987;peptide transport#GO:0015833;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=3367|UniProtKB=O75356 O75356 ENTPD5 PTHR11782:SF35 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 5 nucleotide phosphatase#PC00173 HUMAN|HGNC=20075|UniProtKB=P62068 P62068 USP46 PTHR24006:SF714 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 46 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=10594|UniProtKB=Q01118 Q01118 SCN7A PTHR10037:SF14 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 7 SUBUNIT ALPHA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sodium channel activity#GO:0005272;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;sodium ion transport#GO:0006814;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=26216|UniProtKB=Q08AI8 Q08AI8 MAB21L4 PTHR10656:SF7 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 4 HUMAN|HGNC=24535|UniProtKB=Q9NV06 Q9NV06 DCAF13 PTHR22851:SF0 U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 13 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684 RNA metabolism protein#PC00031 HUMAN|HGNC=15464|UniProtKB=Q9NQ38 Q9NQ38 SPINK5 PTHR10913:SF71 FOLLISTATIN-RELATED SERINE PROTEASE INHIBITOR KAZAL-TYPE 5 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;central nervous system development#GO:0007417;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 protease inhibitor#PC00191 HUMAN|HGNC=33751|UniProtKB=Q5JS37 Q5JS37 NHLRC3 PTHR24104:SF31 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED NHL REPEAT-CONTAINING PROTEIN 3 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 ubiquitin-protein ligase#PC00234 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 HUMAN|HGNC=2219|UniProtKB=Q14050 Q14050 COL9A3 PTHR24023:SF866 COLLAGEN ALPHA COLLAGEN ALPHA-3(IX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 collagen trimer#GO:0005581;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=24552|UniProtKB=Q3LXA3 Q3LXA3 TKFC PTHR28629:SF4 TRIOKINASE/FMN CYCLASE TRIOKINASE/FMN CYCLASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cyclase#PC00079 HUMAN|HGNC=1914|UniProtKB=O95199 O95199 RCBTB2 PTHR22870:SF220 REGULATOR OF CHROMOSOME CONDENSATION RCC1 AND BTB DOMAIN-CONTAINING PROTEIN 2 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=6806|UniProtKB=P43361 P43361 MAGEA8 PTHR11736:SF65 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 8 scaffold/adaptor protein#PC00226 HUMAN|HGNC=13779|UniProtKB=Q9Y225 Q9Y225 RNF24 PTHR22763:SF21 RING ZINC FINGER PROTEIN RING FINGER PROTEIN 24 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=15791|UniProtKB=Q9H490 Q9H490 PIGU PTHR13121:SF0 GPI TRANSAMIDASE COMPONENT PIG-U PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS CLASS U PROTEIN lipid metabolic process#GO:0006629;cellular localization#GO:0051641;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;protein localization to cell surface#GO:0034394;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;cellular macromolecule localization#GO:0070727;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=6638|UniProtKB=Q03252 Q03252 LMNB2 PTHR45721:SF2 LAMIN DM0-RELATED LAMIN-B2 FAS signaling pathway#P00020>Nuclear Lamin#P00616 HUMAN|HGNC=12523|UniProtKB=P11684 P11684 SCGB1A1 PTHR10136:SF6 SECRETOGLOBIN FAMILY 1 MEMBER UTEROGLOBIN cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 cytokine#PC00083 HUMAN|HGNC=2943|UniProtKB=Q6ZR08 Q6ZR08 DNAH12 PTHR46532:SF11 MALE FERTILITY FACTOR KL5 DYNEIN HEAVY CHAIN 12, AXONEMAL HUMAN|HGNC=6377|UniProtKB=O43908 O43908 KLRC4 PTHR22800:SF185 C-TYPE LECTIN PROTEINS NKG2-F TYPE II INTEGRAL MEMBRANE PROTEIN HUMAN|HGNC=19833|UniProtKB=Q7Z6M2 Q7Z6M2 FBXO33 PTHR20933:SF3 F-BOX ONLY PROTEIN 33 F-BOX ONLY PROTEIN 33 HUMAN|HGNC=1708|UniProtKB=A6NJW9 A6NJW9 CD8B2 PTHR11292:SF7 T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN T-CELL SURFACE GLYCOPROTEIN CD8 BETA CHAIN-RELATED cell surface#GO:0009986;cellular anatomical entity#GO:0110165 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=28988|UniProtKB=Q93075 Q93075 TATDN2 PTHR46363:SF1 DEOXYRIBONUCLEASE TATDN2-RELATED DEOXYRIBONUCLEASE TATDN2-RELATED HUMAN|HGNC=15894|UniProtKB=Q9BZ23 Q9BZ23 PANK2 PTHR12280:SF25 PANTOTHENATE KINASE PANTOTHENATE KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 HUMAN|HGNC=20163|UniProtKB=Q9H6D7 Q9H6D7 HAUS4 PTHR16219:SF1 AUGMIN SUBUNIT 4 FAMILY MEMBER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;spindle assembly#GO:0051225;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;spindle organization#GO:0007051;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11868|UniProtKB=P48553 P48553 TRAPPC10 PTHR13251:SF3 EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;TRAPP complex#GO:0030008;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=28073|UniProtKB=Q8N6M9 Q8N6M9 ZFAND2A PTHR14677:SF11 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 2A RNA metabolism protein#PC00031 HUMAN|HGNC=27031|UniProtKB=Q8WVE6 Q8WVE6 TMEM171 PTHR31617:SF0 TRANSMEMBRANE PROTEIN 171 TRANSMEMBRANE PROTEIN 171 HUMAN|HGNC=28843|UniProtKB=Q9HC44 Q9HC44 GPBP1L1 PTHR14339:SF10 VASCULIN VASCULIN-LIKE PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=23352|UniProtKB=Q8WXW3 Q8WXW3 PIBF1 PTHR18950:SF0 PROGESTERONE-INDUCED BLOCKING FACTOR 1 PROGESTERONE-INDUCED-BLOCKING FACTOR 1 HUMAN|HGNC=861|UniProtKB=Q99437 Q99437 ATP6V0B PTHR10263:SF18 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 21 KDA PROTEOLIPID SUBUNIT inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 ATP synthase#PC00002 HUMAN|HGNC=25610|UniProtKB=Q96C11 Q96C11 FGGY PTHR43435:SF4 RIBULOKINASE FGGY CARBOHYDRATE KINASE DOMAIN-CONTAINING PROTEIN carbohydrate kinase#PC00065 Ascorbate degradation#P02729>L-xylulose kinase#P02849;Pentose phosphate pathway#P02762>D-Ribulo Kinase#P03077 HUMAN|HGNC=4056|UniProtKB=P35575 P35575 G6PC PTHR12591:SF3 GLUCOSE-6-PHOSPHATASE GLUCOSE-6-PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;glucose 6-phosphate metabolic process#GO:0051156;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 HUMAN|HGNC=24138|UniProtKB=Q9UF47 Q9UF47 DNAJC5B PTHR44027:SF6 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5B chaperone#PC00072 HUMAN|HGNC=1328|UniProtKB=P20851 P20851 C4BPB PTHR45656:SF8 PROTEIN CBR-CLEC-78 C4B-BINDING PROTEIN BETA CHAIN-RELATED HUMAN|HGNC=26320|UniProtKB=Q96LT4 Q96LT4 SAMD8 PTHR21290:SF25 SPHINGOMYELIN SYNTHETASE SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;intrinsic component of plasma membrane#GO:0031226;Golgi membrane#GO:0000139;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=30535|UniProtKB=Q8WVJ2 Q8WVJ2 NUDCD2 PTHR12356:SF18 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=18731|UniProtKB=Q9BQ51 Q9BQ51 PDCD1LG2 PTHR25466:SF1 T-LYMPHOCYTE ACTIVATION ANTIGEN PROGRAMMED CELL DEATH 1 LIGAND 2 response to external biotic stimulus#GO:0043207;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to molecule of bacterial origin#GO:0002237;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;mononuclear cell proliferation#GO:0032943;negative regulation of T cell proliferation#GO:0042130;response to oxygen-containing compound#GO:1901700;negative regulation of T cell activation#GO:0050868;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;cell adhesion#GO:0007155;response to lipopolysaccharide#GO:0032496;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to lipopolysaccharide#GO:0071222;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;cellular response to lipid#GO:0071396;leukocyte cell-cell adhesion#GO:0007159;T cell proliferation#GO:0042098;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of leukocyte cell-cell adhesion#GO:1903039;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;regulation of T cell proliferation#GO:0042129;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=26892|UniProtKB=Q8NCL9 Q8NCL9 APCDD1L PTHR31021:SF3 ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 PROTEIN APCDD1-LIKE HUMAN|HGNC=1482|UniProtKB=O15484 O15484 CAPN5 PTHR10183:SF402 CALPAIN CALPAIN-5 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=15904|UniProtKB=Q9H8E8 Q9H8E8 KAT14 PTHR20916:SF18 CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN HUMAN|HGNC=19679|UniProtKB=Q2M2I8 Q2M2I8 AAK1 PTHR22967:SF96 SERINE/THREONINE PROTEIN KINASE AP2-ASSOCIATED PROTEIN KINASE 1-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;membrane organization#GO:0061024;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of Notch signaling pathway#GO:0008593;phosphorus metabolic process#GO:0006793;regulation of vesicle-mediated transport#GO:0060627;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of transport#GO:0051049;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of endocytosis#GO:0030100;cellular response to stimulus#GO:0051716;clathrin-dependent endocytosis#GO:0072583;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;localization#GO:0051179;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of receptor-mediated endocytosis#GO:0048259;Notch signaling pathway#GO:0007219 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=18742|UniProtKB=Q9UL41 Q9UL41 PNMA3 PTHR23095:SF22 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN MA3 HUMAN|HGNC=8087|UniProtKB=P29728 P29728 OAS2 PTHR11258:SF3 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE 2 adenylyltransferase activity#GO:0070566;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;double-stranded RNA binding#GO:0003725 response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA phosphodiester bond hydrolysis#GO:0090501;regulation of catalytic activity#GO:0050790;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;defense response to other organism#GO:0098542;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 HUMAN|HGNC=11921|UniProtKB=O95407 O95407 TNFRSF6B PTHR23097:SF116 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6B transmembrane signal receptor#PC00197 HUMAN|HGNC=644|UniProtKB=P10275 P10275 AR PTHR48092:SF13 KNIRPS-RELATED PROTEIN-RELATED ANDROGEN RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;reproductive system development#GO:0061458;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;reproductive structure development#GO:0048608;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;male sex differentiation#GO:0046661;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;sex differentiation#GO:0007548;cellular metabolic process#GO:0044237;male gonad development#GO:0008584;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;reproduction#GO:0000003;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Gonadotropin-releasing hormone receptor pathway#P06664>AR#P06774 HUMAN|HGNC=12383|UniProtKB=Q53HC9 Q53HC9 EIPR1 PTHR14205:SF15 WD-REPEAT PROTEIN EARP AND GARP COMPLEX-INTERACTING PROTEIN 1 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=10984|UniProtKB=O95258 O95258 SLC25A14 PTHR45618:SF20 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED BRAIN MITOCHONDRIAL CARRIER PROTEIN 1 secondary carrier transporter#PC00258 HUMAN|HGNC=25888|UniProtKB=Q53GT1 Q53GT1 KLHL22 PTHR45632:SF5 LD33804P KELCH-LIKE PROTEIN 22 HUMAN|HGNC=2204|UniProtKB=Q01955 Q01955 COL4A3 PTHR24023:SF877 COLLAGEN ALPHA COLLAGEN ALPHA-3(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=30228|UniProtKB=Q4J6C6 Q4J6C6 PREPL PTHR11757:SF19 PROTEASE FAMILY S9A OLIGOPEPTIDASE PROLYL ENDOPEPTIDASE-LIKE serine protease#PC00203 Vasopressin synthesis#P04395>Endo Peptidase#P04596 HUMAN|HGNC=14367|UniProtKB=Q8TDM0 Q8TDM0 BCAS4 PTHR16230:SF5 CAPPUCCINO BREAST CARCINOMA-AMPLIFIED SEQUENCE 4 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622;BLOC-1 complex#GO:0031083 HUMAN|HGNC=25112|UniProtKB=Q96IR2 Q96IR2 ZNF845 PTHR24376:SF74 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 845 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15672|UniProtKB=Q9H6U8 Q9H6U8 ALG9 PTHR22760:SF2 GLYCOSYLTRANSFERASE ALPHA-1,2-MANNOSYLTRANSFERASE ALG9 transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=28875|UniProtKB=Q8WZ79 Q8WZ79 DNASE2B PTHR10858:SF2 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE-2-BETA hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;endodeoxyribonuclease activity#GO:0004520;deoxyribonuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;heterocycle catabolic process#GO:0046700;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;plasma membrane bounded cell projection organization#GO:0120036;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;DNA catabolic process, endonucleolytic#GO:0000737;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;cell projection assembly#GO:0030031;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;plasma membrane bounded cell projection assembly#GO:0120031;DNA metabolic process#GO:0006259 endodeoxyribonuclease#PC00093 HUMAN|HGNC=19958|UniProtKB=O15091 O15091 PRORP PTHR13547:SF1 UNCHARACTERIZED MITOCHONDRIAL RIBONUCLEASE P CATALYTIC SUBUNIT catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;ribonuclease activity#GO:0004540 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=6499|UniProtKB=P11279 P11279 LAMP1 PTHR11506:SF27 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;cellular protein localization#GO:0034613;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=13158|UniProtKB=P51522 P51522 ZNF83 PTHR23226:SF324 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 525-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28996|UniProtKB=Q92541 Q92541 RTF1 PTHR13115:SF8 UNCHARACTERIZED RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=21250|UniProtKB=Q6UWE3 Q6UWE3 CLPSL2 PTHR10041:SF3 COLIPASE COLIPASE-LIKE PROTEIN 2 response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;response to chemical#GO:0042221 protein-binding activity modulator#PC00095 HUMAN|HGNC=6694|UniProtKB=P98164 P98164 LRP2 PTHR22722:SF11 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2 Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 HUMAN|HGNC=4381|UniProtKB=Q14344 Q14344 GNA13 PTHR10218:SF85 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-13 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 positive regulation of lipase activity#GO:0060193;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of phospholipase activity#GO:0010517;Ras protein signal transduction#GO:0007265;positive regulation of molecular function#GO:0044093;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;cell communication#GO:0007154;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;positive regulation of hydrolase activity#GO:0051345;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoplasmic side of membrane#GO:0098562;microvillus#GO:0005902;membrane protein complex#GO:0098796;leaflet of membrane bilayer#GO:0097478;brush border#GO:0005903;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cluster of actin-based cell projections#GO:0098862;catalytic complex#GO:1902494;cell projection membrane#GO:0031253;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;side of membrane#GO:0098552;polymeric cytoskeletal fiber#GO:0099513;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;cytoskeleton#GO:0005856;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 HUMAN|HGNC=29036|UniProtKB=Q96H78 Q96H78 SLC25A44 PTHR46314:SF2 SOLUTE CARRIER FAMILY 25 MEMBER 44 SOLUTE CARRIER FAMILY 25 MEMBER 44 secondary carrier transporter#PC00258 HUMAN|HGNC=14479|UniProtKB=Q7Z2W9 Q7Z2W9 MRPL21 PTHR21349:SF0 50S RIBOSOMAL PROTEIN L21 39S RIBOSOMAL PROTEIN L21, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202 Methylcitrate cycle#P02754>Aconitase#P03028 HUMAN|HGNC=600|UniProtKB=P02647 P02647 APOA1 PTHR18976:SF11 APOLIPOPROTEIN APOLIPOPROTEIN A-I apolipoprotein#PC00052 HUMAN|HGNC=40030|UniProtKB=Q71RC9 Q71RC9 SMIM5 PTHR37344:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 5 SMALL INTEGRAL MEMBRANE PROTEIN 5 HUMAN|HGNC=29548|UniProtKB=Q9BQ95 Q9BQ95 ECSIT PTHR13113:SF1 ECSIT EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAY, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>ECSIT#P01349 HUMAN|HGNC=5293|UniProtKB=P28223 P28223 HTR2A PTHR24247:SF30 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2A cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=4489|UniProtKB=Q49SQ1 Q49SQ1 GPR33 PTHR24225:SF5 CHEMOTACTIC RECEPTOR G-PROTEIN COUPLED RECEPTOR 33-RELATED complement binding#GO:0001848;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;immune response-regulating signaling pathway#GO:0002764;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;activation of immune response#GO:0002253;divalent inorganic cation homeostasis#GO:0072507;regulation of lipase activity#GO:0060191;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;immune response-activating signal transduction#GO:0002757;activation of phospholipase C activity#GO:0007202;regulation of immune system process#GO:0002682;regulation of hydrolase activity#GO:0051336;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;cellular cation homeostasis#GO:0030003;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;regulation of immune response#GO:0050776;positive regulation of phospholipase activity#GO:0010518;positive regulation of immune system process#GO:0002684;homeostatic process#GO:0042592;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;metal ion homeostasis#GO:0055065 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=3293|UniProtKB=O60573 O60573 EIF4E2 PTHR11960:SF62 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2 translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;RNA cap binding#GO:0000339 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=17888|UniProtKB=O75575 O75575 CRCP PTHR15561:SF0 CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;intracellular#GO:0005622;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;transferase complex#GO:1990234;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 G-protein coupled receptor#PC00021 HUMAN|HGNC=9632|UniProtKB=Q86YD1 Q86YD1 PTOV1 PTHR12433:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 PROSTATE TUMOR-OVEREXPRESSED GENE 1 PROTEIN positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=7549|UniProtKB=Q00872 Q00872 MYBPC1 PTHR13817:SF27 TITIN MYOSIN-BINDING PROTEIN C, SLOW-TYPE HUMAN|HGNC=9207|UniProtKB=Q9UFF9 Q9UFF9 CNOT8 PTHR10797:SF1 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 8 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cellular protein metabolic process#GO:0032269;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;intracellular#GO:0005622;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=14254|UniProtKB=Q9UK39 Q9UK39 NOCT PTHR12121:SF45 CARBON CATABOLITE REPRESSOR PROTEIN 4 NOCTURNIN catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity#GO:0003824;ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=566|UniProtKB=O00203 O00203 AP3B1 PTHR11134:SF10 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA-1 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;axo-dendritic transport#GO:0008088;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 membrane traffic protein#PC00150 HUMAN|HGNC=20225|UniProtKB=Q92782 Q92782 DPF1 PTHR10615:SF12 HISTONE ACETYLTRANSFERASE ZINC FINGER PROTEIN NEURO-D4 molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=7667|UniProtKB=P19338 P19338 NCL PTHR48034:SF4 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED NUCLEOLIN positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;positive regulation of RNA metabolic process#GO:0051254;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=28965|UniProtKB=P42696 P42696 RBM34 PTHR23236:SF85 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H RNA-BINDING PROTEIN 34 translation initiation factor#PC00224 HUMAN|HGNC=20893|UniProtKB=Q6W2J9 Q6W2J9 BCOR PTHR24117:SF8 AGAP007537-PB BCL-6 COREPRESSOR-RELATED HUMAN|HGNC=26075|UniProtKB=Q9NWS0 Q9NWS0 PIH1D1 PTHR22997:SF0 UNCHARACTERIZED PIH1 DOMAIN-CONTAINING PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=10637|UniProtKB=P02778 P02778 CXCL10 PTHR10179:SF47 CXC CHEMOKINE C-X-C MOTIF CHEMOKINE 10 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=4809|UniProtKB=Q9UJM8 Q9UJM8 HAO1 PTHR10578:SF137 S -2-HYDROXY-ACID OXIDASE-RELATED HYDROXYACID OXIDASE 1 oxidoreductase#PC00176 HUMAN|HGNC=12509|UniProtKB=Q9UHD9 Q9UHD9 UBQLN2 PTHR10677:SF5 UBIQUILIN UBIQUILIN-2 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;regulation of macroautophagy#GO:0016241;response to organonitrogen compound#GO:0010243;cellular component organization#GO:0016043;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;organelle assembly#GO:0070925;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;autophagosome organization#GO:1905037;ubiquitin-dependent ERAD pathway#GO:0030433;autophagosome assembly#GO:0000045;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=18640|UniProtKB=Q5SW96 Q5SW96 LDLRAP1 PTHR11232:SF35 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER LOW DENSITY LIPOPROTEIN RECEPTOR ADAPTER PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|Gene=EIF2S3L|UniProtKB=Q2VIR3 Q2VIR3 EIF2S3B PTHR42854:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3B tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;heterocyclic compound binding#GO:1901363 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;ribonucleoprotein complex subunit organization#GO:0071826;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;translation#GO:0006412;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;translational initiation#GO:0006413;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|Ensembl=ENSG00000223590|UniProtKB=A0A0G2JKD1 A0A0G2JKD1 MUC21 PTHR39408:SF3 MUCIN-21 MUCIN-21 HUMAN|HGNC=18458|UniProtKB=Q9BWX1 Q9BWX1 PHF7 PTHR12420:SF40 PHD FINGER PROTEIN PHD FINGER PROTEIN 7 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=33340|UniProtKB=Q1W6H9 Q1W6H9 FAM110C PTHR14758:SF5 AGAP005440-PA PROTEIN FAM110C HUMAN|HGNC=24966|UniProtKB=Q9H063 Q9H063 MAF1 PTHR22504:SF0 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 general transcription factor#PC00259 HUMAN|HGNC=25402|UniProtKB=Q96G74 Q96G74 OTUD5 PTHR12419:SF4 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 5 hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081 HUMAN|HGNC=680|UniProtKB=Q99819 Q99819 ARHGDIG PTHR10980:SF8 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 3 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rho GTPase binding#GO:0017048;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;Rac GTPase binding#GO:0048365;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 G-protein modulator#PC00022 HUMAN|HGNC=20478|UniProtKB=Q8NEX6 Q8NEX6 WFDC11 PTHR19441:SF12 WHEY ACDIC PROTEIN WAP PROTEIN WFDC11 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antibacterial humoral response#GO:0019731;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=27315|UniProtKB=Q0P670 Q0P670 SPEM2 PTHR34834:SF2 SPERMATID MATURATION PROTEIN 1 SPEM1 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=9601|UniProtKB=Q9P2B2 Q9P2B2 PTGFRN PTHR12207:SF3 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN PROSTAGLANDIN F2 RECEPTOR NEGATIVE REGULATOR intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=24239|UniProtKB=O75069 O75069 TMCC2 PTHR17613:SF9 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAINS PROTEIN 2 organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=28769|UniProtKB=Q6UX65 Q6UX65 DRAM2 PTHR21324:SF10 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED DNA DAMAGE-REGULATED AUTOPHAGY MODULATOR PROTEIN 2 process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;biological regulation#GO:0065007;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;cellular catabolic process#GO:0044248;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12738|UniProtKB=Q969T9 Q969T9 WBP2 PTHR31606:SF4 WW DOMAIN BINDING PROTEIN 2, ISOFORM E WW DOMAIN-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;transcription coactivator activity#GO:0003713;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10389|UniProtKB=P62244 P62244 RPS15A PTHR11758:SF13 40S RIBOSOMAL PROTEIN S15A 40S RIBOSOMAL PROTEIN S15A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=3673|UniProtKB=O60258 O60258 FGF17 PTHR11486:SF71 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 17 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=21876|UniProtKB=Q6NUQ1 Q6NUQ1 RINT1 PTHR13520:SF0 RAD50-INTERACTING PROTEIN 1 RINT-1 RAD50-INTERACTING PROTEIN 1 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;regulation of response to DNA damage stimulus#GO:2001020;nuclear division#GO:0000280;regulation of localization#GO:0032879;regulation of intracellular signal transduction#GO:1902531;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;regulation of cellular localization#GO:0060341;mitotic DNA integrity checkpoint#GO:0044774;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;cell cycle G2/M phase transition#GO:0044839;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;mitotic cell cycle phase transition#GO:0044772;regulation of signaling#GO:0023051;transport#GO:0006810;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;regulation of transport#GO:0051049;signal transduction in response to DNA damage#GO:0042770;G2 DNA damage checkpoint#GO:0031572;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;regulation of response to stress#GO:0080134;mitotic DNA damage checkpoint#GO:0044773;negative regulation of mitotic cell cycle#GO:0045930;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;organelle organization#GO:0006996;mitotic G2 DNA damage checkpoint#GO:0007095;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=16700|UniProtKB=Q8WW38 Q8WW38 ZFPM2 PTHR12958:SF5 FRIEND OF GATA2-RELATED ZINC FINGER PROTEIN ZFPM2 RNA polymerase II transcription factor binding#GO:0001085;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;heart development#GO:0007507;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=13517|UniProtKB=Q9NZA1 Q9NZA1 CLIC5 PTHR45476:SF4 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN 5 ion channel#PC00133 HUMAN|HGNC=1678|UniProtKB=P01730 P01730 CD4 PTHR11422:SF0 T-CELL SURFACE GLYCOPROTEIN CD4 T-CELL SURFACE GLYCOPROTEIN CD4 HUMAN|HGNC=17759|UniProtKB=Q5T2R2 Q5T2R2 PDSS1 PTHR12001:SF78 GERANYLGERANYL PYROPHOSPHATE SYNTHASE DECAPRENYL-DIPHOSPHATE SYNTHASE SUBUNIT 1 prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;small molecule biosynthetic process#GO:0044283;ubiquinone biosynthetic process#GO:0006744;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 HUMAN|HGNC=37274|UniProtKB=Q5JSQ8 Q5JSQ8 KHDC1L PTHR31368:SF5 DEVELOPMENT PLURPOTENCY-ASSOCIATED PROTEIN 1/5 FAMILY MEMBER KHDC1-LIKE PROTEIN-RELATED RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of cellular protein metabolic process#GO:0032270;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;positive regulation of cell death#GO:0010942;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=17185|UniProtKB=Q8WXI3 Q8WXI3 ASB10 PTHR24123:SF126 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 10 scaffold/adaptor protein#PC00226 HUMAN|HGNC=30025|UniProtKB=Q5VV67 Q5VV67 PPRC1 PTHR15528:SF5 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR-RELATED PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;molecular function regulator#GO:0098772;nuclear receptor transcription coactivator activity#GO:0030374;transcription factor binding#GO:0008134 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=23689|UniProtKB=Q5T848 Q5T848 GPR158 PTHR32546:SF11 G-PROTEIN COUPLED RECEPTOR 158-RELATED G-PROTEIN COUPLED RECEPTOR 158-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=20362|UniProtKB=Q9Y4F5 Q9Y4F5 CEP170B PTHR15715:SF18 CENTROSOMAL PROTEIN OF 170 KDA CENTROSOMAL PROTEIN OF 170 KDA PROTEIN B scaffold/adaptor protein#PC00226 HUMAN|HGNC=11058|UniProtKB=Q9NS82 Q9NS82 SLC7A10 PTHR11785:SF73 AMINO ACID TRANSPORTER ASC-TYPE AMINO ACID TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;alanine transport#GO:0032328;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 transporter#PC00227 HUMAN|HGNC=2329|UniProtKB=Q92523 Q92523 CPT1B PTHR22589:SF69 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 1, MUSCLE ISOFORM transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=974|UniProtKB=O75363 O75363 BCAS1 PTHR15016:SF6 BREAST CARCINOMA-AMPLIFIED SEQUENCE 1 BREAST CARCINOMA-AMPLIFIED SEQUENCE 1 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 HUMAN|HGNC=18012|UniProtKB=A0A024RBG1 A0A024RBG1 NUDT4B PTHR12629:SF6 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 2-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleotide diphosphatase activity#GO:0004551;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organophosphate catabolic process#GO:0046434;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphatase#PC00181 HUMAN|HGNC=11787|UniProtKB=P49746 P49746 THBS3 PTHR10199:SF89 THROMBOSPONDIN THROMBOSPONDIN-3 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=3128|UniProtKB=P32249 P32249 GPR183 PTHR24237:SF7 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 183 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=8889|UniProtKB=P15259 P15259 PGAM2 PTHR11931:SF8 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE 2 mutase#PC00160 Glycolysis#P00024>Phosphoglyceromutase#P00680 HUMAN|HGNC=1734|UniProtKB=P49427 P49427 CDC34 PTHR24067:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 R1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=4808|UniProtKB=P61296 P61296 HAND2 PTHR23349:SF41 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HEART- AND NEURAL CREST DERIVATIVES-EXPRESSED PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=30611|UniProtKB=Q8TCJ2 Q8TCJ2 STT3B PTHR13872:SF1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B glycosyltransferase#PC00111 HUMAN|HGNC=918|UniProtKB=O75752 O75752 B3GALNT1 PTHR11214:SF153 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=10436|UniProtKB=P23443 P23443 RPS6KB1 PTHR24351:SF48 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE BETA-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 CCKR signaling map#P06959>p70S6K1#P07031;p53 pathway by glucose deprivation#P04397>S6K#P04636;PI3 kinase pathway#P00048>S6K#P01194;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 HUMAN|HGNC=19235|UniProtKB=Q9NY61 Q9NY61 AATF PTHR15565:SF0 AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR PROTEIN AATF intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=30950|UniProtKB=Q9UID6 Q9UID6 ZNF639 PTHR24404:SF35 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 639 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=31675|UniProtKB=Q9Y5A9 Q9Y5A9 YTHDF2 PTHR12357:SF8 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN 2 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of translational initiation#GO:0045948;gene expression#GO:0010467;regulation of translational initiation#GO:0006446;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular biosynthetic process#GO:0031326;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;translational initiation#GO:0006413;positive regulation of RNA metabolic process#GO:0051254;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=20672|UniProtKB=Q9UPP1 Q9UPP1 PHF8 PTHR23123:SF11 PHD/F-BOX CONTAINING PROTEIN HISTONE LYSINE DEMETHYLASE PHF8 molecular function regulator#GO:0098772;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;demethylation#GO:0070988;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein demethylation#GO:0006482;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=11356|UniProtKB=Q9UJ98 Q9UJ98 STAG3 PTHR11199:SF8 STROMAL ANTIGEN COHESIN SUBUNIT SA-3-RELATED binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;chromatin#GO:0000785;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=17418|UniProtKB=A8MXT2 A8MXT2 MAGEB17 PTHR11736:SF88 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B17 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26182|UniProtKB=Q8NBJ5 Q8NBJ5 COLGALT1 PTHR10730:SF28 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN GALACTOSYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 protein modifying enzyme#PC00260 HUMAN|HGNC=13136|UniProtKB=Q15940 Q15940 ZNF726P1 PTHR24377:SF912 IP01015P-RELATED ZINC FINGER PROTEIN 254-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16209|UniProtKB=Q9NQG5 Q9NQG5 RPRD1B PTHR12460:SF3 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 1B basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 kinase inhibitor#PC00139 HUMAN|HGNC=26813|UniProtKB=Q8N8J7 Q8N8J7 FAM241A PTHR33690:SF1 DUF4605 DOMAIN-CONTAINING PROTEIN DUF4605 DOMAIN-CONTAINING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=30054|UniProtKB=Q8TCE9 Q8TCE9 LGALS14 PTHR11346:SF15 GALECTIN PLACENTAL PROTEIN 13-LIKE extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=27001|UniProtKB=Q496M5 Q496M5 PLK5 PTHR24345:SF43 SERINE/THREONINE-PROTEIN KINASE PLK INACTIVE SERINE/THREONINE-PROTEIN KINASE PLK5 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cell division#GO:0051301;membrane fission#GO:0090148;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;regulation of cell division#GO:0051302;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of cytokinesis#GO:0032465;cytokinesis#GO:0000910 spindle pole#GO:0000922;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=30494|UniProtKB=Q68DE3 Q68DE3 USF3 PTHR46970:SF1 BASIC HELIX-LOOP-HELIX DOMAIN-CONTAINING PROTEIN USF3 BASIC HELIX-LOOP-HELIX DOMAIN-CONTAINING PROTEIN USF3 cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;regulation of biological process#GO:0050789;system development#GO:0048731;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;mesenchyme development#GO:0060485;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of cellular process#GO:0048523 HUMAN|HGNC=16646|UniProtKB=O60575 O60575 SPINK4 PTHR21179:SF0 SERINE-TYPE ENDOPEPTIDASE INHIBITOR SERINE PROTEASE INHIBITOR KAZAL-TYPE 4 protease inhibitor#PC00191 HUMAN|HGNC=7529|UniProtKB=P53602 P53602 MVD PTHR10977:SF3 DIPHOSPHOMEVALONATE DECARBOXYLASE DIPHOSPHOMEVALONATE DECARBOXYLASE decarboxylase#PC00089 Cholesterol biosynthesis#P00014>Diphosphomevalonate decarboxylase#P00496 HUMAN|HGNC=18648|UniProtKB=Q86TI2 Q86TI2 DPP9 PTHR11731:SF109 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 9 serine protease#PC00203 HUMAN|HGNC=15231|UniProtKB=Q8NH56 Q8NH56 OR52N5 PTHR26450:SF18 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N5 transmembrane signal receptor#PC00197 HUMAN|HGNC=28408|UniProtKB=Q8IZ02 Q8IZ02 LRRC34 PTHR24111:SF0 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 HUMAN|HGNC=25893|UniProtKB=Q96K80 Q96K80 ZC3H10 PTHR12675:SF6 MUSCLEBLIND-LIKE PROTEIN ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 10 RNA splicing factor#PC00148 HUMAN|HGNC=11299|UniProtKB=P37108 P37108 SRP14 PTHR12013:SF2 SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=8716|UniProtKB=Q9UN70 Q9UN70 PCDHGC3 PTHR24028:SF70 CADHERIN-87A PROTOCADHERIN GAMMA-C3 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=14791|UniProtKB=Q8NGH8 Q8NGH8 OR56A4 PTHR24248:SF110 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 56A4-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=29189|UniProtKB=Q9UPR6 Q9UPR6 ZFR2 PTHR45762:SF2 ZINC FINGER RNA-BINDING PROTEIN ZINC FINGER RNA-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=26153|UniProtKB=Q68E01 Q68E01 INTS3 PTHR13587:SF7 INTEGRATOR COMPLEX SUBUNIT 3 INTEGRATOR COMPLEX SUBUNIT 3 HUMAN|HGNC=21711|UniProtKB=Q7Z570 Q7Z570 ZNF804A PTHR17614:SF13 ZINC FINGER-CONTAINING ZINC FINGER PROTEIN 804A HUMAN|HGNC=5551|UniProtKB=A0A0C4DH33 A0A0C4DH33 IGHV1-24 PTHR23266:SF275 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-24 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=19112|UniProtKB=P59541 P59541 TAS2R30 PTHR11394:SF48 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 30 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=24316|UniProtKB=Q9BSH4 Q9BSH4 TACO1 PTHR12532:SF0 UNCHARACTERIZED TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 HUMAN|HGNC=1753|UniProtKB=P55290 P55290 CDH13 PTHR24027:SF80 CADHERIN-23 CADHERIN-13 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;circulatory system development#GO:0072359;cell-cell junction assembly#GO:0007043;blood vessel morphogenesis#GO:0048514;developmental process#GO:0032502;multicellular organism development#GO:0007275;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;tube development#GO:0035295;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;tube morphogenesis#GO:0035239;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;sprouting angiogenesis#GO:0002040;cell junction assembly#GO:0034329 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=9064|UniProtKB=Q9UPR0 Q9UPR0 PLCL2 PTHR10336:SF84 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN INACTIVE PHOSPHOLIPASE C-LIKE PROTEIN 2 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 HUMAN|HGNC=30461|UniProtKB=Q68DY1 Q68DY1 ZNF626 PTHR24384:SF129 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 626 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=3254|UniProtKB=Q9BY44 Q9BY44 EIF2A PTHR13227:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2A EUKARYOTIC TRANSLATION INITIATION FACTOR 2A tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 translation initiation factor#PC00224 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2A#P06762 HUMAN|HGNC=30542|UniProtKB=Q8TEQ0 Q8TEQ0 SNX29 PTHR47194:SF2 SORTING NEXIN-29-RELATED SORTING NEXIN-29-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=10938|UniProtKB=O60779 O60779 SLC19A2 PTHR10686:SF19 FOLATE TRANSPORTER THIAMINE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=9130|UniProtKB=A8MQ11 A8MQ11 PMS2P5 PTHR10073:SF52 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MISMATCH REPAIR ENDONUCLEASE PMS2-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=23428|UniProtKB=Q8TAT2 Q8TAT2 FGFBP3 PTHR15258:SF3 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 3 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 HUMAN|HGNC=618|UniProtKB=O14791 O14791 APOL1 PTHR14096:SF55 APOLIPOPROTEIN L APOLIPOPROTEIN L1 lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052 HUMAN|HGNC=20823|UniProtKB=Q8N608 Q8N608 DPP10 PTHR11731:SF21 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED INACTIVE DIPEPTIDYL PEPTIDASE 10 serine protease#PC00203 HUMAN|HGNC=21493|UniProtKB=Q8WXU2 Q8WXU2 DNAAF4 PTHR46492:SF1 DYNEIN ASSEMBLY FACTOR 4, AXONEMAL DYNEIN ASSEMBLY FACTOR 4, AXONEMAL microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;inner dynein arm assembly#GO:0036159;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;axonemal dynein complex assembly#GO:0070286;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=33771|UniProtKB=A0A494C191 A0A494C191 SPDYE9P PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=17077|UniProtKB=O14595 O14595 CTDSP2 PTHR12210:SF171 NUCLEAR LIM INTERACTOR-INTERACTING FACTOR-RELATED CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 HUMAN|Gene_ORFName=CGI-142|UniProtKB=Q9Y3E1 Q9Y3E1 HDGFL3 PTHR12550:SF78 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR-RELATED PROTEIN 3 nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=34410|UniProtKB=Q96JN8 Q96JN8 NEURL4 PTHR12429:SF14 NEURALIZED NEURALIZED-LIKE PROTEIN 4 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 ubiquitin-protein ligase#PC00234 Notch signaling pathway#P00045>Neuralized#P01117 HUMAN|HGNC=24291|UniProtKB=Q8IZ52 Q8IZ52 CHPF PTHR12369:SF22 CHONDROITIN SYNTHASE CHONDROITIN SULFATE SYNTHASE 2 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;chondroitin sulfate metabolic process#GO:0030204;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;proteoglycan metabolic process#GO:0006029;chondroitin sulfate proteoglycan metabolic process#GO:0050654;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;glycosaminoglycan biosynthetic process#GO:0006024;small molecule metabolic process#GO:0044281 glycosyltransferase#PC00111 HUMAN|HGNC=18632|UniProtKB=Q86VH2 Q86VH2 KIF27 PTHR24115:SF889 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF27 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=16692|UniProtKB=Q9NPF0 Q9NPF0 CD320 PTHR24270:SF27 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED CD320 ANTIGEN apolipoprotein#PC00052 HUMAN|HGNC=792|UniProtKB=P17544 P17544 ATF7 PTHR19304:SF10 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302 HUMAN|HGNC=2531|UniProtKB=Q9UBX1 Q9UBX1 CTSF PTHR12411:SF444 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN F cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=44408|UniProtKB=H3BV12 H3BV12 GOLGA8Q PTHR10881:SF62 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8H-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=3492|UniProtKB=P41162 P41162 ETV3 PTHR11849:SF30 ETS ETS TRANSLOCATION VARIANT 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=6256|UniProtKB=P78508 P78508 KCNJ10 PTHR11767:SF21 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=8962|UniProtKB=Q07326 Q07326 PIGF PTHR43157:SF31 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED glycosyltransferase#PC00111 HUMAN|HGNC=23017|UniProtKB=O75063 O75063 FAM20B PTHR12450:SF14 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 GLYCOSAMINOGLYCAN XYLOSYLKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=583|UniProtKB=P25054 P25054 APC PTHR12607:SF11 ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY ADENOMATOUS POLYPOSIS COLI PROTEIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488;beta-catenin binding#GO:0008013 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule catabolic process#GO:0009057;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;localization of cell#GO:0051674;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cell communication#GO:0007154;cell fate commitment#GO:0045165;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of protein catabolic process#GO:0045732;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of microtubule-based process#GO:0032886;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;microtubule depolymerization#GO:0007019;regulation of signaling#GO:0023051;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of cell differentiation#GO:0045595;cell fate specification#GO:0001708;system development#GO:0048731;cell differentiation#GO:0030154;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;negative regulation of organelle organization#GO:0010639;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;pattern specification process#GO:0007389;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of supramolecular fiber organization#GO:1902903;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;microtubule-based process#GO:0007017;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell migration#GO:0016477 supramolecular complex#GO:0099080;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cytoplasmic microtubule#GO:0005881;extrinsic component of plasma membrane#GO:0019897;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 Wnt signaling pathway#P00057>APC#P01468;Angiogenesis#P00005>APC#P00195 HUMAN|HGNC=15567|UniProtKB=Q9UJC5 Q9UJC5 SH3BGRL2 PTHR12232:SF4 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=28089|UniProtKB=Q8TE69 Q8TE69 EOLA1 PTHR31666:SF0 PROTEIN CXORF40A-RELATED PROTEIN EOLA1-RELATED HUMAN|HGNC=8503|UniProtKB=P22059 P22059 OSBP PTHR10972:SF52 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 1 lipid binding#GO:0008289;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;lipid transporter activity#GO:0005319;steroid binding#GO:0005496;sterol binding#GO:0032934 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=21212|UniProtKB=Q8N7X0 Q8N7X0 ADGB PTHR46298:SF1 ANDROGLOBIN ANDROGLOBIN HUMAN|HGNC=28685|UniProtKB=Q56VL3 Q56VL3 OCIAD2 PTHR13336:SF2 OVARIAN CARCINOMA IMMUNOREACTIVE ANTIGEN OCIA DOMAIN-CONTAINING PROTEIN 2 envelope#GO:0031975;mitochondrial membrane#GO:0031966;endosome#GO:0005768;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=17408|UniProtKB=Q6NZY7 Q6NZY7 CDC42EP5 PTHR15344:SF15 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 5 HUMAN|HGNC=3223|UniProtKB=P52797 P52797 EFNA3 PTHR11304:SF5 EPHRIN EPHRIN-A3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=10369|UniProtKB=P32969 P32969 RPL9P8 PTHR11655:SF26 60S/50S RIBOSOMAL PROTEIN L6/L9 60S RIBOSOMAL PROTEIN L9 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=18414|UniProtKB=Q96RP3 Q96RP3 UCN2 PTHR17575:SF0 UROCORTIN-2 AND 3 UROCORTIN-2 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular response to extracellular stimulus#GO:0031668;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to hormone#GO:0009725;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=9839|UniProtKB=P11233 P11233 RALA PTHR24070:SF174 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 vesicle fusion#GO:0006906;signal transduction#GO:0007165;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;Ras protein signal transduction#GO:0007265;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;cellular response to stimulus#GO:0051716;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;membrane fusion#GO:0061025;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;export from cell#GO:0140352 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 Ras Pathway#P04393>Ral#P04550 HUMAN|HGNC=1565|UniProtKB=O00590 O00590 ACKR2 PTHR10489:SF942 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 2 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 HUMAN|HGNC=338|UniProtKB=P50052 P50052 AGTR2 PTHR24228:SF8 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR TYPE-2 ANGIOTENSIN II RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;system process#GO:0003008;regulation of blood vessel diameter#GO:0097746;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;defense response#GO:0006952;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=10047|UniProtKB=P34096 P34096 RNASE4 PTHR11437:SF53 RIBONUCLEASE RIBONUCLEASE 4 HUMAN|HGNC=7562|UniProtKB=Q99836 Q99836 MYD88 PTHR15079:SF3 MYD88 MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88 scaffold/adaptor protein#PC00226 Toll pathway-drosophila#P06217>MyD88#P06346;Toll receptor signaling pathway#P00054>MyD88#P01377 HUMAN|HGNC=3241|UniProtKB=Q05215 Q05215 EGR4 PTHR23235:SF58 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15892|UniProtKB=Q9Y3B1 Q9Y3B1 PRELID3B PTHR11158:SF22 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING PROTEIN 3B binding#GO:0005488;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 HUMAN|HGNC=24224|UniProtKB=Q9NYV4 Q9NYV4 CDK12 PTHR24056:SF126 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 12 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;phosphorylation#GO:0016310;DNA-templated transcription, elongation#GO:0006354;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;transcription elongation from RNA polymerase II promoter#GO:0006368;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=226|UniProtKB=P78563 P78563 ADARB1 PTHR10910:SF58 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN DOUBLE-STRANDED RNA-SPECIFIC EDITASE 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;double-stranded RNA binding#GO:0003725 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=29243|UniProtKB=Q9P2N5 Q9P2N5 RBM27 PTHR14398:SF1 RNA RECOGNITION RRM/RNP DOMAIN RNA-BINDING PROTEIN 27 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;positive regulation of transport#GO:0051050;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;positive regulation of cellular process#GO:0048522;RNA localization#GO:0006403;localization#GO:0051179;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;positive regulation of biological process#GO:0048518;nuclear transport#GO:0051169 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=6354|UniProtKB=Q9UH77 Q9UH77 KLHL3 PTHR24412:SF179 KELCH PROTEIN KELCH-LIKE PROTEIN 3 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15594|UniProtKB=Q9UK59 Q9UK59 DBR1 PTHR12849:SF0 RNA LARIAT DEBRANCHING ENZYME LARIAT DEBRANCHING ENZYME catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 endoribonuclease#PC00094 HUMAN|HGNC=19414|UniProtKB=Q6NUT2 Q6NUT2 DPY19L2 PTHR31488:SF6 DPY-19-LIKE 1, LIKE (H. SAPIENS) C-MANNOSYLTRANSFERASE DPY19L2-RELATED transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;male gamete generation#GO:0048232;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;spermatid differentiation#GO:0048515;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;nitrogen compound metabolic process#GO:0006807;spermatogenesis#GO:0007283;reproductive process#GO:0022414;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;multi-organism reproductive process#GO:0044703;protein mannosylation#GO:0035268;multicellular organismal reproductive process#GO:0048609;mannosylation#GO:0097502;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;germ cell development#GO:0007281;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;gamete generation#GO:0007276;macromolecule biosynthetic process#GO:0009059;multicellular organism reproduction#GO:0032504;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;multi-organism process#GO:0051704;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;developmental process involved in reproduction#GO:0003006;carbohydrate derivative biosynthetic process#GO:1901137;cell development#GO:0048468;spermatid development#GO:0007286;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;glycosylation#GO:0070085 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=21256|UniProtKB=Q5TGU0 Q5TGU0 TSPO2 PTHR10057:SF4 PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR TRANSLOCATOR PROTEIN 2 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|Ensembl=ENSG00000284244|UniProtKB=A0A1W2PQM1 A0A1W2PQM1 ENSG00000284244 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=2174|UniProtKB=Q8IWV2 Q8IWV2 CNTN4 PTHR10075:SF63 BASIGIN RELATED CONTACTIN-4 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15469|UniProtKB=O75061 O75061 DNAJC6 PTHR23172:SF4 AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED TYROSINE-PROTEIN PHOSPHATASE AUXILIN-RELATED protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;protein-containing complex disassembly#GO:0032984;cellular protein complex disassembly#GO:0043624;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;protein-containing complex subunit organization#GO:0043933;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;vesicle#GO:0031982;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279 membrane traffic protein#PC00150 HUMAN|HGNC=27223|UniProtKB=Q96EV2 Q96EV2 RBM33 PTHR22014:SF2 RNA-BINDING PROTEIN 33 RNA-BINDING PROTEIN 33 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 HUMAN|HGNC=14014|UniProtKB=Q9Y316 Q9Y316 MEMO1 PTHR11060:SF1 PROTEIN MEMO1 PROTEIN MEMO1 HUMAN|HGNC=1876|UniProtKB=O15519 O15519 CFLAR PTHR10454:SF8 CASPASE CASP8 AND FADD-LIKE APOPTOSIS REGULATOR cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of proteolysis#GO:0045862;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;negative regulation of apoptotic signaling pathway#GO:2001234;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of metabolic process#GO:0009893;positive regulation of programmed cell death#GO:0043068;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell death#GO:0010942 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 FAS signaling pathway#P00020>Caspase8#P00594;Apoptosis signaling pathway#P00006>Flip#P00284;FAS signaling pathway#P00020>Pro-Caspase8#P00604 HUMAN|HGNC=11604|UniProtKB=Q99593 Q99593 TBX5 PTHR11267:SF28 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 specification of symmetry#GO:0009799;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;heart looping#GO:0001947;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;heart development#GO:0007507;embryonic heart tube development#GO:0035050;determination of heart left/right asymmetry#GO:0061371;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;determination of bilateral symmetry#GO:0009855;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;determination of left/right symmetry#GO:0007368;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=29526|UniProtKB=Q0VDF9 Q0VDF9 HSPA14 PTHR19375:SF438 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 14 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ATP binding#GO:0005524;ATPase activity#GO:0016887 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;chaperone-mediated protein folding#GO:0061077;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;ubiquitin-dependent ERAD pathway#GO:0030433;'de novo' protein folding#GO:0006458;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;ribosome#GO:0005840;plasma membrane#GO:0005886 HUMAN|HGNC=17934|UniProtKB=Q9NZ20 Q9NZ20 PLA2G3 PTHR12253:SF19 RH14732P GROUP 3 SECRETORY PHOSPHOLIPASE A2 HUMAN|HGNC=2194|UniProtKB=Q9UMD9 Q9UMD9 COL17A1 PTHR24023:SF891 COLLAGEN ALPHA COLLAGEN ALPHA-1(XVII) CHAIN-RELATED structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=2311|UniProtKB=P14384 P14384 CPM PTHR11532:SF84 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE M hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190 HUMAN|HGNC=73|UniProtKB=P45844 P45844 ABCG1 PTHR48041:SF90 ABC TRANSPORTER G FAMILY MEMBER 28 ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 1 pyrophosphatase activity#GO:0016462;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 biological regulation#GO:0065007;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;regulation of biological quality#GO:0065008;cholesterol homeostasis#GO:0042632 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=19562|UniProtKB=A4D2G3 A4D2G3 OR2A25 PTHR26451:SF146 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 2A25 HUMAN|HGNC=14294|UniProtKB=Q9BYB0 Q9BYB0 SHANK3 PTHR24135:SF4 SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular component biogenesis#GO:0044085;regulation of dendrite development#GO:0050773;positive regulation of signal transduction#GO:0009967;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of transmembrane transporter activity#GO:0022898;central nervous system development#GO:0007417;positive regulation of cell development#GO:0010720;regulation of transporter activity#GO:0032409;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;regulation of multicellular organismal process#GO:0051239;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of synaptic plasticity#GO:0048167;cellular component organization or biogenesis#GO:0071840;regulation of ion transmembrane transport#GO:0034765;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;head development#GO:0060322;signal transduction#GO:0007165;neurogenesis#GO:0022008;regulation of signaling#GO:0023051;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of system process#GO:0044057;cation transport#GO:0006812;ionotropic glutamate receptor signaling pathway#GO:0035235;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;system development#GO:0048731;neuron differentiation#GO:0030182;cell junction assembly#GO:0034329;signaling#GO:0023052;cell-cell signaling#GO:0007267;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;cell morphogenesis#GO:0000902;nervous system process#GO:0050877;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of signaling receptor activity#GO:0010469;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;synapse assembly#GO:0007416;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;positive regulation of cellular component organization#GO:0051130;positive regulation of synaptic transmission#GO:0050806;synaptic transmission, glutamatergic#GO:0035249;cell projection organization#GO:0030030;dendrite development#GO:0016358;system process#GO:0003008;brain development#GO:0007420;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;dendritic spine organization#GO:0097061;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;regulation of dendritic spine development#GO:0060998;trans-synaptic signaling#GO:0099537;ion transmembrane transport#GO:0034220;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;neuromuscular junction development#GO:0007528;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;synapse organization#GO:0050808;neuron projection development#GO:0031175;modulation of chemical synaptic transmission#GO:0050804;regulation of cell projection organization#GO:0031344;neuron projection morphogenesis#GO:0048812;regulation of ion transport#GO:0043269;regulation of trans-synaptic signaling#GO:0099177;neuron development#GO:0048666;positive regulation of multicellular organismal process#GO:0051240;positive regulation of cell projection organization#GO:0031346;regulation of neurotransmitter receptor activity#GO:0099601;chemical synaptic transmission, postsynaptic#GO:0099565;animal organ development#GO:0048513;transport#GO:0006810;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;cation transmembrane transport#GO:0098655;positive regulation of response to stimulus#GO:0048584;regulation of transport#GO:0051049;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;positive regulation of neuron differentiation#GO:0045666;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;developmental growth#GO:0048589;regulation of cation transmembrane transport#GO:1904062;positive regulation of cell differentiation#GO:0045597;ion transport#GO:0006811;multicellular organism development#GO:0007275;regulation of AMPA receptor activity#GO:2000311;positive regulation of developmental process#GO:0051094;dendrite morphogenesis#GO:0048813;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;organelle assembly#GO:0070925;response to stimulus#GO:0050896;organelle organization#GO:0006996;cell junction organization#GO:0034330;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;generation of neurons#GO:0048699 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;cell junction#GO:0030054;ion channel complex#GO:0034702;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 Ionotropic glutamate receptor pathway#P00037>PSD95#P00999 HUMAN|HGNC=13834|UniProtKB=Q9BZ76 Q9BZ76 CNTNAP3 PTHR15036:SF36 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN FAMILY MEMBER 3C-RELATED HUMAN|HGNC=30961|UniProtKB=O60844 O60844 ZG16 PTHR33589:SF4 OS11G0524900 PROTEIN ZYMOGEN GRANULE MEMBRANE PROTEIN 16 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=8158|UniProtKB=Q9UBM4 Q9UBM4 OPTC PTHR24370:SF11 OPTICIN OPTICIN extracellular matrix protein#PC00102 HUMAN|HGNC=30860|UniProtKB=P83369 P83369 LSM11 PTHR21415:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=8908|UniProtKB=Q15124 Q15124 PGM5 PTHR22573:SF27 PHOSPHOHEXOMUTASE FAMILY MEMBER PHOSPHOGLUCOMUTASE-LIKE PROTEIN 5 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;muscle tissue development#GO:0060537;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cytosol#GO:0005829;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;sarcolemma#GO:0042383;plasma membrane#GO:0005886 mutase#PC00160 HUMAN|HGNC=24586|UniProtKB=Q9H1A3 Q9H1A3 METTL9 PTHR12890:SF0 DREV PROTEIN METHYLTRANSFERASE-LIKE PROTEIN 9 HUMAN|HGNC=5413|UniProtKB=Q01629 Q01629 IFITM2 PTHR13999:SF8 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 2 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to cytokine#GO:0034097;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;innate immune response#GO:0045087;defense response to virus#GO:0051607;cytokine-mediated signaling pathway#GO:0019221;defense response#GO:0006952;signaling#GO:0023052;immune effector process#GO:0002252;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;cell communication#GO:0007154;cellular process#GO:0009987;response to type I interferon#GO:0034340;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;type I interferon signaling pathway#GO:0060337 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=4668|UniProtKB=Q9Y5Q8 Q9Y5Q8 GTF3C5 PTHR13230:SF5 GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 general transcription factor#PC00259 HUMAN|HGNC=34332|UniProtKB=Q9Y2P0 Q9Y2P0 ZNF835 PTHR24404:SF76 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 835 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13082|UniProtKB=O94822 O94822 LTN1 PTHR12389:SF0 ZINC FINGER PROTEIN 294 E3 UBIQUITIN-PROTEIN LIGASE LISTERIN transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ribonucleoprotein complex binding#GO:0043021;ubiquitin-like protein ligase activity#GO:0061659;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;translation#GO:0006412;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;proteasomal protein catabolic process#GO:0010498;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular macromolecule biosynthetic process#GO:0034645;modification-dependent protein catabolic process#GO:0019941;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=19904|UniProtKB=Q9C0G0 Q9C0G0 ZNF407 PTHR24403:SF60 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 407 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=30726|UniProtKB=Q5T0N1 Q5T0N1 CFAP70 PTHR44314:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70 structural protein#PC00211 HUMAN|HGNC=20530|UniProtKB=P59991 P59991 KRTAP12-2 PTHR23262:SF180 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 12-1-RELATED HUMAN|HGNC=25278|UniProtKB=Q8N5Q1 Q8N5Q1 FAM71E2 PTHR22574:SF12 UNCHARACTERIZED PROTEIN FAM71E2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=18133|UniProtKB=Q9H2K8 Q9H2K8 TAOK3 PTHR48015:SF14 SERINE/THREONINE-PROTEIN KINASE TAO SERINE/THREONINE-PROTEIN KINASE TAO3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=3689|UniProtKB=P21802 P21802 FGFR2 PTHR24416:SF130 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;fibroblast growth factor binding#GO:0017134;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 HUMAN|HGNC=95|UniProtKB=O00400 O00400 SLC33A1 PTHR12778:SF9 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED ACETYL-COENZYME A TRANSPORTER 1 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;carbohydrate derivative transport#GO:1901264;transport#GO:0006810 secondary carrier transporter#PC00258 HUMAN|HGNC=26676|UniProtKB=Q5T655 Q5T655 CFAP58 PTHR32083:SF31 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 58 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 structural protein#PC00211 HUMAN|HGNC=20232|UniProtKB=Q8N8G2 Q8N8G2 VGLL2 PTHR15950:SF17 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=559|UniProtKB=P61966 P61966 AP1S1 PTHR11753:SF14 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-1A localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 HUMAN|HGNC=26932|UniProtKB=Q9Y2S6 Q9Y2S6 TMA7 PTHR28632:SF11 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=28995|UniProtKB=Q6P996 Q6P996 PDXDC1 PTHR42735:SF10 FAMILY NOT NAMED PYRIDOXAL-DEPENDENT DECARBOXYLASE DOMAIN-CONTAINING PROTEIN 1-RELATED lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell motility#GO:0048870;lipid catabolic process#GO:0016042;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;localization#GO:0051179;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;movement of cell or subcellular component#GO:0006928;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477;locomotion#GO:0040011;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=17810|UniProtKB=Q4VCS5 Q4VCS5 AMOT PTHR14826:SF6 ANGIOMOTIN ANGIOMOTIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 establishment or maintenance of cell polarity#GO:0007163;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;developmental process#GO:0032502;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;system development#GO:0048731;establishment of cell polarity#GO:0030010;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;cytoskeleton organization#GO:0007010;vasculature development#GO:0001944;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of cellular component movement#GO:0051270;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;tube development#GO:0035295;localization of cell#GO:0051674;cell communication#GO:0007154;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;hippo signaling#GO:0035329;response to stimulus#GO:0050896;angiogenesis#GO:0001525;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 intracellular vesicle#GO:0097708;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;cell leading edge#GO:0031252;intracellular#GO:0005622;lamellipodium#GO:0030027;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;apical junction complex#GO:0043296;plasma membrane#GO:0005886 HUMAN|HGNC=14901|UniProtKB=Q969J5 Q969J5 IL22RA2 PTHR20859:SF51 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|Gene=LPPR5|UniProtKB=Q32ZL2 Q32ZL2 PLPPR5 PTHR10165:SF17 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 5 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphatase#PC00181 HUMAN|HGNC=30259|UniProtKB=Q96GD0 Q96GD0 PDXP PTHR19288:SF75 4-NITROPHENYLPHOSPHATASE-RELATED PYRIDOXAL PHOSPHATE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311;metabolic process#GO:0008152 phosphatase#PC00181 HUMAN|HGNC=5569|UniProtKB=A0A0B4J2B8 A0A0B4J2B8 IGHV1OR15-9 PTHR23266:SF100 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=32375|UniProtKB=A6NN73 A6NN73 GOLGA8CP PTHR10881:SF7 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8C-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=12858|UniProtKB=P43403 P43403 ZAP70 PTHR24418:SF369 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ZAP-70 T cell activation#P00053>ZAP-70#P01308 HUMAN|HGNC=33482|UniProtKB=A1L020 A1L020 MEX3A PTHR23285:SF2 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3A RNA metabolism protein#PC00031 HUMAN|HGNC=24842|UniProtKB=Q3B8N2 Q3B8N2 LGALS9B PTHR11346:SF80 GALECTIN GALECTIN-9B carbohydrate derivative binding#GO:0097367;carbohydrate binding#GO:0030246;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of biological process#GO:0048519;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;gene expression#GO:0010467;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;cytokine production#GO:0001816;leukocyte cell-cell adhesion#GO:0007159;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;negative regulation of multicellular organismal process#GO:0051241;T cell proliferation#GO:0042098;positive regulation of metabolic process#GO:0009893;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;negative regulation of cell population proliferation#GO:0008285;regulation of gene expression#GO:0010468;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;lymphocyte activation#GO:0046649;regulation of cell population proliferation#GO:0042127;negative regulation of T cell activation#GO:0050868;macromolecule metabolic process#GO:0043170;cell-cell adhesion#GO:0098609;negative regulation of metabolic process#GO:0009892;lymphocyte proliferation#GO:0046651;cell adhesion#GO:0007155;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;regulation of T cell proliferation#GO:0042129;negative regulation of cell adhesion#GO:0007162;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;regulation of macromolecule metabolic process#GO:0060255;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;multicellular organismal process#GO:0032501;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250;regulation of leukocyte proliferation#GO:0070663;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 extracellular matrix protein#PC00102 HUMAN|HGNC=8380|UniProtKB=Q8NG98 Q8NG98 OR7D4 PTHR48001:SF138 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D4 transmembrane signal receptor#PC00197 HUMAN|HGNC=53837|UniProtKB=P0DPQ3 P0DPQ3 PRR20G PTHR38819:SF1 PROLINE-RICH PROTEIN 20A-RELATED PROLINE-RICH PROTEIN 20A-RELATED HUMAN|HGNC=25834|UniProtKB=Q9H8G2 Q9H8G2 CAAP1 PTHR14740:SF3 CASPASE ACTIVITY AND APOPTOSIS INHIBITOR 1 CASPASE ACTIVITY AND APOPTOSIS INHIBITOR 1 regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;regulation of apoptotic signaling pathway#GO:2001233;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;negative regulation of apoptotic signaling pathway#GO:2001234;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;negative regulation of endopeptidase activity#GO:0010951;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043154;negative regulation of signal transduction#GO:0009968;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of hydrolase activity#GO:0051346;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell death#GO:0010941;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 HUMAN|HGNC=5622|UniProtKB=A0A0B4J1Y9 A0A0B4J1Y9 IGHV3-72 PTHR23266:SF114 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-72 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=24225|UniProtKB=Q17RY6 Q17RY6 LY6K PTHR15049:SF1 GLYCOSYL-PHOSPHATIDYLINOSITOL-ANCHORED MOLECULE-LIKE PROTEIN-RELATED LYMPHOCYTE ANTIGEN 6K cell recognition#GO:0008037;fertilization#GO:0009566;reproduction#GO:0000003;single fertilization#GO:0007338;sexual reproduction#GO:0019953;reproductive process#GO:0022414;sperm-egg recognition#GO:0035036;cellular process#GO:0009987;multi-organism reproductive process#GO:0044703;multi-organism process#GO:0051704;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=23452|UniProtKB=Q5VXI9 Q5VXI9 LIPN PTHR11005:SF16 LYSOSOMAL ACID LIPASE-RELATED LIPASE MEMBER N membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 lipase#PC00143 HUMAN|HGNC=32068|UniProtKB=Q5TGZ0 Q5TGZ0 MICOS10 PTHR21304:SF5 UNCHARACTERIZED MICOS COMPLEX SUBUNIT MIC10 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=21054|UniProtKB=Q86UC2 Q86UC2 RSPH3 PTHR21648:SF0 FLAGELLAR RADIAL SPOKE PROTEIN 3 RADIAL SPOKE HEAD PROTEIN 3 HOMOLOG structural protein#PC00211 HUMAN|HGNC=30287|UniProtKB=Q8N122 Q8N122 RPTOR PTHR12848:SF16 REGULATORY-ASSOCIATED PROTEIN OF MTOR REGULATORY-ASSOCIATED PROTEIN OF MTOR protein binding#GO:0005515;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;response to extracellular stimulus#GO:0009991;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;positive regulation of growth#GO:0045927;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of cell growth#GO:0030307;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;growth#GO:0040007;protein modification process#GO:0036211;regulation of growth#GO:0040008;regulation of catalytic activity#GO:0050790;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;process utilizing autophagic mechanism#GO:0061919;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;cellular response to starvation#GO:0009267;regulation of protein serine/threonine kinase activity#GO:0071900;catabolic process#GO:0009056;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;regulation of cell growth#GO:0001558;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;cell growth#GO:0016049;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=1656|UniProtKB=O95400 O95400 CD2BP2 PTHR13138:SF3 PROTEIN LIN1 CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682 RNA splicing factor#PC00148 HUMAN|HGNC=19721|UniProtKB=Q8WVQ1 Q8WVQ1 CANT1 PTHR13023:SF3 APYRASE SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE 1 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 nucleotide phosphatase#PC00173 HUMAN|HGNC=24992|UniProtKB=Q9Y5V0 Q9Y5V0 ZNF706 PTHR21213:SF27 GEO09665P1-RELATED ZINC FINGER PROTEIN 706 HUMAN|HGNC=33257|UniProtKB=Q6ZN06 Q6ZN06 ZNF813 PTHR24377:SF644 IP01015P-RELATED ZINC FINGER PROTEIN 813 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8510|UniProtKB=Q92882 Q92882 OSTF1 PTHR24155:SF10 OSTEOCLAST-STIMULATING FACTOR 1 OSTEOCLAST-STIMULATING FACTOR 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 HUMAN|HGNC=14074|UniProtKB=Q9NZ56 Q9NZ56 FMN2 PTHR13037:SF16 FORMIN FORMIN-2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 localization#GO:0051179;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=25078|UniProtKB=O75425 O75425 MOSPD3 PTHR10809:SF55 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN MOTILE SPERM DOMAIN-CONTAINING PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;membrane organization#GO:0061024;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=9112|UniProtKB=Q6P1K2 Q6P1K2 PMF1 PTHR15459:SF4 POLYAMINE-MODULATED FACTOR 1 POLYAMINE-MODULATED FACTOR 1 cellular process#GO:0009987;chromosome segregation#GO:0007059 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;kinetochore#GO:0000776;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;condensed chromosome, centromeric region#GO:0000779;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;condensed nuclear chromosome kinetochore#GO:0000778;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;chromosomal region#GO:0098687 HUMAN|HGNC=29144|UniProtKB=Q8NDI1 Q8NDI1 EHBP1 PTHR23167:SF43 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED EH DOMAIN-BINDING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856 HUMAN|HGNC=26024|UniProtKB=Q9H9L4 Q9H9L4 KANSL2 PTHR13453:SF1 UNCHARACTERIZED KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;H4 histone acetyltransferase activity#GO:0010485;N-acyltransferase activity#GO:0016410 peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;histone H4 acetylation#GO:0043967;chromatin organization#GO:0006325;histone H4-K16 acetylation#GO:0043984;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=35240|UniProtKB=A6NCL7 A6NCL7 ANKRD33B PTHR24173:SF1 FAMILY NOT NAMED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 33B HUMAN|HGNC=29962|UniProtKB=Q5JRC9 Q5JRC9 FAM47A PTHR47415:SF4 PROTEIN FAM47B PROTEIN FAM47A HUMAN|HGNC=13842|UniProtKB=A2RRD8 A2RRD8 ZNF320 PTHR24377:SF197 IP01015P-RELATED ZINC FINGER PROTEIN 320 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8854|UniProtKB=O00623 O00623 PEX12 PTHR12888:SF2 PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12 PEROXISOME ASSEMBLY PROTEIN 12 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;protein import into peroxisome matrix#GO:0016558;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;protein targeting to peroxisome#GO:0006625;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein localization to organelle#GO:0033365;cellular protein metabolic process#GO:0044267;protein import#GO:0017038;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein localization to peroxisome#GO:0072662;transmembrane transport#GO:0055085;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;microbody membrane#GO:0031903;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;integral component of peroxisomal membrane#GO:0005779;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;microbody#GO:0042579 chaperone#PC00072 HUMAN|HGNC=20175|UniProtKB=Q9Y3E0 Q9Y3E0 GOLT1B PTHR21493:SF79 CGI-141-RELATED/LIPASE CONTAINING PROTEIN VESICLE TRANSPORT PROTEIN GOT1B cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 lipase#PC00143 HUMAN|HGNC=7568|UniProtKB=P35580 P35580 MYH10 PTHR45615:SF24 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-10 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=33705|UniProtKB=Q6UWW9 Q6UWW9 TMEM207 PTHR36467:SF1 TRANSMEMBRANE PROTEIN 207 TRANSMEMBRANE PROTEIN 207 HUMAN|HGNC=2516|UniProtKB=Q9UQB3 Q9UQB3 CTNND2 PTHR10372:SF9 PLAKOPHILLIN-RELATED CATENIN DELTA-2 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;dendrite development#GO:0016358;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;dendritic spine organization#GO:0097061;neuron differentiation#GO:0030182;cell junction assembly#GO:0034329;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular developmental process#GO:0048869;cell-cell junction organization#GO:0045216;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;dendrite morphogenesis#GO:0048813;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;cytoplasm#GO:0005737;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;adherens junction#GO:0005912;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130 Cadherin signaling pathway#P00012>P120#P00473 HUMAN|HGNC=20361|UniProtKB=Q969W0 Q969W0 SPTSSA PTHR47084:SF1 SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT A SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT A transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 protein modifying enzyme#PC00260 HUMAN|HGNC=245|UniProtKB=Q9UEY8 Q9UEY8 ADD3 PTHR10672:SF5 ADDUCIN GAMMA-ADDUCIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 plasma membrane raft#GO:0044853;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;asymmetric synapse#GO:0032279;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;plasma membrane region#GO:0098590;postsynapse#GO:0098794;membrane raft#GO:0045121;cytoskeleton#GO:0005856;membrane region#GO:0098589;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 HUMAN|HGNC=2888|UniProtKB=Q9NRI5 Q9NRI5 DISC1 PTHR14332:SF3 DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;axoneme assembly#GO:0035082;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;regulation of multicellular organismal process#GO:0051239;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;regulation of neuron differentiation#GO:0045664;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;regulation of neuron projection development#GO:0010975;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;developmental process#GO:0032502;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;amide transport#GO:0042886;organic substance transport#GO:0071702;system development#GO:0048731;cell differentiation#GO:0030154;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;protein localization to organelle#GO:0033365;regulation of cell development#GO:0060284;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cell development#GO:0048468;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;regulation of neurogenesis#GO:0050767;microtubule-based process#GO:0007017;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;neuron migration#GO:0001764;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;generation of neurons#GO:0048699;cell migration#GO:0016477 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;intermediate filament cytoskeleton#GO:0045111;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;centriole#GO:0005814;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 HUMAN|HGNC=10002|UniProtKB=P49758 P49758 RGS6 PTHR45746:SF2 LP21163P REGULATOR OF G-PROTEIN SIGNALING 6 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=9640|UniProtKB=Q6Y1H2 Q6Y1H2 HACD2 PTHR11035:SF17 PTPLA DOMAIN PROTEIN VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 2 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=5829|UniProtKB=A0A0C4DH55 A0A0C4DH55 IGKV3D-7 PTHR23267:SF331 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=25730|UniProtKB=Q5W5X9 Q5W5X9 TTC23 PTHR14485:SF3 TETRATRICOPEPTIDE REPEAT PROTEIN 23 TETRATRICOPEPTIDE REPEAT PROTEIN 23 HUMAN|HGNC=11992|UniProtKB=Q13472 Q13472 TOP3A PTHR11390:SF21 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-ALPHA DNA metabolism protein#PC00009 HUMAN|HGNC=15886|UniProtKB=Q9Y312 Q9Y312 AAR2 PTHR12689:SF4 A1 CISTRON SPLICING FACTOR AAR2-RELATED PROTEIN AAR2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 RNA splicing factor#PC00148 HUMAN|HGNC=9249|UniProtKB=Q86W92 Q86W92 PPFIBP1 PTHR12587:SF16 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-BETA-1 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330;neuromuscular junction development#GO:0007528 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 HUMAN|Ensembl=ENSG00000283988|UniProtKB=A0A1W2PR64 A0A1W2PR64 TAF11L9 PTHR13218:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TAFII28 DOMAIN-CONTAINING PROTEIN transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=16306|UniProtKB=Q96B70 Q96B70 LENG9 PTHR46729:SF1 LEUKOCYTE RECEPTOR CLUSTER MEMBER 9 LEUKOCYTE RECEPTOR CLUSTER MEMBER 9 HUMAN|HGNC=18019|UniProtKB=Q9H8U3 Q9H8U3 ZFAND3 PTHR10634:SF134 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 3 HUMAN|HGNC=17056|UniProtKB=Q9Y2J0 Q9Y2J0 RPH3A PTHR45729:SF3 RABPHILIN, ISOFORM A RABPHILIN-3A HUMAN|HGNC=28471|UniProtKB=Q8WUJ1 Q8WUJ1 CYB5D2 PTHR10281:SF4 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED NEUFERRICIN cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=6657|UniProtKB=Q8TBB1 Q8TBB1 LNX1 PTHR19964:SF14 MULTIPLE PDZ DOMAIN PROTEIN E3 UBIQUITIN-PROTEIN LIGASE LNX Notch signaling pathway#P00045>LNXp80#P01111 HUMAN|HGNC=3530|UniProtKB=P00748 P00748 F12 PTHR24264:SF46 TRYPSIN-RELATED COAGULATION FACTOR XII serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;regulation of body fluid levels#GO:0050878;wound healing#GO:0042060;hemostasis#GO:0007599;coagulation#GO:0050817;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;rough endoplasmic reticulum#GO:0005791;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 serine protease#PC00203 Blood coagulation#P00011>FXII#P00442;Blood coagulation#P00011>FXIIa#P00441 HUMAN|HGNC=11340|UniProtKB=Q15532 Q15532 SS18 PTHR23107:SF2 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN PROTEIN SSXT positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=14073|UniProtKB=Q13733 Q13733 ATP1A4 PTHR43294:SF3 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-4 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;potassium ion transport#GO:0006813;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;cellular monovalent inorganic cation homeostasis#GO:0030004;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725;export from cell#GO:0140352 primary active transporter#PC00068 HUMAN|HGNC=7530|UniProtKB=Q03426 Q03426 MVK PTHR43290:SF2 MEVALONATE KINASE MEVALONATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 carbohydrate kinase#PC00065 Cholesterol biosynthesis#P00014>Mevalonate kinase#P00492 HUMAN|HGNC=7605|UniProtKB=Q9UM54 Q9UM54 MYO6 PTHR13140:SF745 MYOSIN UNCONVENTIONAL MYOSIN-VI pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;vesicle organization#GO:0016050;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=1862|UniProtKB=O95813 O95813 CER1 PTHR15273:SF4 DAN DOMAIN FAMILY MEMBER 5 CERBERUS Wnt signaling pathway#P00057>Cerebus#P01445 HUMAN|HGNC=29452|UniProtKB=Q9Y6H3 Q9Y6H3 ATP23 PTHR21711:SF0 MITOCHONDRIAL INNER MEMBRANE PROTEASE MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial protein processing#GO:0034982;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;mitochondrion organization#GO:0007005;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 metalloprotease#PC00153 HUMAN|HGNC=7586|UniProtKB=Q02045 Q02045 MYL5 PTHR23049:SF8 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN LIGHT CHAIN 5 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=26790|UniProtKB=Q3MJ13 Q3MJ13 WDR72 PTHR44099:SF2 RABCONNECTIN-3B, ISOFORM A WD REPEAT-CONTAINING PROTEIN 72 HUMAN|HGNC=6074|UniProtKB=Q96PE3 Q96PE3 INPP4A PTHR12187:SF4 AGAP000124-PA INOSITOL POLYPHOSPHATE-4-PHOSPHATASE TYPE I A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2050|UniProtKB=P56748 P56748 CLDN8 PTHR12002:SF24 CLAUDIN CLAUDIN-8 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=24437|UniProtKB=Q96KP4 Q96KP4 CNDP2 PTHR43270:SF11 BETA-ALA-HIS DIPEPTIDASE CYTOSOLIC NON-SPECIFIC DIPEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=21559|UniProtKB=Q9UJ04 Q9UJ04 TSPYL4 PTHR11875:SF33 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 4 protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=28184|UniProtKB=Q9BRQ6 Q9BRQ6 CHCHD6 PTHR47609:SF1 MICOS COMPLEX SUBUNIT MIC25 MICOS COMPLEX SUBUNIT MIC25 cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;membrane organization#GO:0061024;organelle organization#GO:0006996;cristae formation#GO:0042407;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;cellular response to stress#GO:0033554;inner mitochondrial membrane organization#GO:0007007 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4909|UniProtKB=Q14526 Q14526 HIC1 PTHR24394:SF16 ZINC FINGER PROTEIN HYPERMETHYLATED IN CANCER 1 PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=12597|UniProtKB=Q9Y6N9 Q9Y6N9 USH1C PTHR23116:SF36 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED HARMONIN 9+0 non-motile cilium#GO:0097731;supramolecular complex#GO:0099080;non-motile cilium#GO:0097730;cluster of actin-based cell projections#GO:0098862;actin-based cell projection#GO:0098858;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;stereocilium#GO:0032420;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;stereocilium bundle#GO:0032421;actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=14701|UniProtKB=Q8NGS9 Q8NGS9 OR13C2 PTHR26453:SF616 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C2 transmembrane signal receptor#PC00197 HUMAN|HGNC=32152|UniProtKB=Q8WW27 Q8WW27 APOBEC4 PTHR35672:SF1 C-U-EDITING ENZYME APOBEC-4-RELATED C-U-EDITING ENZYME APOBEC-4-RELATED HUMAN|HGNC=24893|UniProtKB=Q75WM6 Q75WM6 H1-7 PTHR11467:SF14 HISTONE H1 TESTIS-SPECIFIC H1 HISTONE nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 positive regulation of gene expression#GO:0010628;male gamete generation#GO:0048232;cellular component biogenesis#GO:0044085;negative regulation of chromosome organization#GO:2001251;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of cellular component organization#GO:0051128;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;gene silencing#GO:0016458;reproductive process#GO:0022414;regulation of chromatin organization#GO:1902275;protein-containing complex subunit organization#GO:0043933;gamete generation#GO:0007276;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular aromatic compound metabolic process#GO:0006725;chromatin assembly or disassembly#GO:0006333;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;chromosome condensation#GO:0030261;chromatin assembly#GO:0031497;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;multi-organism process#GO:0051704;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of DNA recombination#GO:0000018;negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of chromatin silencing#GO:0031935;regulation of RNA biosynthetic process#GO:2001141;negative regulation of chromatin silencing#GO:0031936;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;spermatogenesis#GO:0007283;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;regulation of gene expression, epigenetic#GO:0040029;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;RNA biosynthetic process#GO:0032774;positive regulation of cellular process#GO:0048522;developmental process involved in reproduction#GO:0003006;DNA packaging#GO:0006323;sexual reproduction#GO:0019953;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular biosynthetic process#GO:0031327;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;nucleosome organization#GO:0034728;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;regulation of gene expression#GO:0010468;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;multicellular organism reproduction#GO:0032504;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;negative regulation of gene expression, epigenetic#GO:0045814;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone#PC00118 HUMAN|HGNC=9181|UniProtKB=Q9Y253 Q9Y253 POLH PTHR45873:SF1 DNA POLYMERASE ETA DNA POLYMERASE ETA transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;DNA polymerase activity#GO:0034061;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;cellular nitrogen compound biosynthetic process#GO:0044271;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;replication fork#GO:0005657 DNA metabolism protein#PC00009 HUMAN|HGNC=24149|UniProtKB=Q9HCC6 Q9HCC6 HES4 PTHR10985:SF136 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 HUMAN|HGNC=29953|UniProtKB=Q8WWZ8 Q8WWZ8 OIT3 PTHR14002:SF18 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ONCOPROTEIN-INDUCED TRANSCRIPT 3 PROTEIN localization#GO:0051179;leukocyte migration#GO:0050900;granulocyte migration#GO:0097530;immune system process#GO:0002376;myeloid leukocyte migration#GO:0097529;neutrophil migration#GO:1990266;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 cell surface#GO:0009986;extracellular region#GO:0005576;plasma membrane region#GO:0098590;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=10581|UniProtKB=Q9UQR0 Q9UQR0 SCML2 PTHR12247:SF84 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 2 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=6616|UniProtKB=P48059 P48059 LIMS1 PTHR24210:SF11 LIM DOMAIN-CONTAINING PROTEIN LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 1-RELATED regulation of cell morphogenesis involved in differentiation#GO:0010769;signal transduction#GO:0007165;positive regulation of cell-substrate adhesion#GO:0010811;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of signal transduction#GO:0009967;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;substrate adhesion-dependent cell spreading#GO:0034446;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;integrin-mediated signaling pathway#GO:0007229;regulation of cell adhesion#GO:0030155;positive regulation of cell development#GO:0010720;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cell-cell junction organization#GO:0045216;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;cell junction organization#GO:0034330;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cell adhesion#GO:0045785 cytoplasm#GO:0005737;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 HUMAN|HGNC=11321|UniProtKB=O43805 O43805 SSNA1 PTHR28661:SF1 SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 1 SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 1 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=17181|UniProtKB=Q9NWX5 Q9NWX5 ASB6 PTHR24132:SF24 ANKYRIN REPEAT AND SOCS BOX PROTEIN 6 ANKYRIN REPEAT AND SOCS BOX PROTEIN 6 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28844|UniProtKB=Q6PIJ6 Q6PIJ6 FBXO38 PTHR14753:SF3 F-BOX ONLY PROTEIN 38 F-BOX ONLY PROTEIN 38 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9618|UniProtKB=Q13308 Q13308 PTK7 PTHR26391:SF16 INACTIVE TYROSINE-PROTEIN KINASE 7 INACTIVE TYROSINE-PROTEIN KINASE 7 developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;anatomical structure morphogenesis#GO:0009653;epithelium development#GO:0060429;anatomical structure development#GO:0048856;developmental process#GO:0032502;tissue morphogenesis#GO:0048729;growth#GO:0040007;morphogenesis of an epithelium#GO:0002009;establishment of planar polarity#GO:0001736;tissue development#GO:0009888 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 tyrosine protein kinase receptor#PC00233 HUMAN|HGNC=4514|UniProtKB=Q9P1P5 Q9P1P5 TAAR2 PTHR24249:SF220 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 2 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=13966|UniProtKB=Q9GZK3 Q9GZK3 OR2B2 PTHR26453:SF254 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2B2 transmembrane signal receptor#PC00197 HUMAN|HGNC=30096|UniProtKB=Q9Y3B4 Q9Y3B4 SF3B6 PTHR12785:SF7 SPLICING FACTOR 3B SPLICING FACTOR 3B SUBUNIT 6 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974;U12-type spliceosomal complex#GO:0005689 RNA splicing factor#PC00148 HUMAN|HGNC=20607|UniProtKB=Q8N6R1 Q8N6R1 SERP2 PTHR15601:SF20 STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4 STRESS-ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN 2 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=14542|UniProtKB=Q9Y3S1 Q9Y3S1 WNK2 PTHR13902:SF10 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE/THREONINE-PROTEIN KINASE WNK2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;transferase activity, transferring phosphorus-containing groups#GO:0016772;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;transporter activity#GO:0005215;kinase activity#GO:0016301;channel activity#GO:0015267;protein kinase activity#GO:0004672;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;transferase activity#GO:0016740;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;protein serine/threonine kinase activity#GO:0004674;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890 regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of transmembrane transport#GO:0034764;divalent inorganic cation transport#GO:0072511;regulation of transmembrane transporter activity#GO:0022898;intracellular signal transduction#GO:0035556;regulation of transporter activity#GO:0032409;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;regulation of calcium ion transport#GO:0051924;cellular metabolic process#GO:0044237;positive regulation of transport#GO:0051050;cell communication#GO:0007154;negative regulation of transport#GO:0051051;ion transmembrane transport#GO:0034220;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;regulation of ion transport#GO:0043269;positive regulation of ion transport#GO:0043270;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of potassium ion transmembrane transport#GO:1901379;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;ion homeostasis#GO:0050801;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;positive regulation of ion transmembrane transporter activity#GO:0032414;homeostatic process#GO:0042592;protein phosphorylation#GO:0006468;cellular process#GO:0009987;chemical homeostasis#GO:0048878;positive regulation of calcium ion transport#GO:0051928;localization#GO:0051179;response to stimulus#GO:0050896;sodium ion transport#GO:0006814;positive regulation of transporter activity#GO:0032411;positive regulation of ion transmembrane transport#GO:0034767;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;sodium ion transmembrane transport#GO:0035725 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=22973|UniProtKB=A3KN83 A3KN83 SBNO1 PTHR12706:SF8 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH HOMOLOG 1 nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;histone binding#GO:0042393 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=17631|UniProtKB=Q9GZS1 Q9GZS1 POLR1E PTHR14440:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;transcription, DNA-templated#GO:0006351;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;DNA-templated transcription, elongation#GO:0006354;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=3167|UniProtKB=Q99500 Q99500 S1PR3 PTHR22750:SF24 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=17428|UniProtKB=Q9UHV5 Q9UHV5 RAPGEFL1 PTHR23113:SF230 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR-LIKE 1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=18154|UniProtKB=Q9Y4L5 Q9Y4L5 RNF115 PTHR15710:SF16 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF115 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=27318|UniProtKB=Q8IVC4 Q8IVC4 ZNF584 PTHR24377:SF611 IP01015P-RELATED ZINC FINGER PROTEIN 584 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28728|UniProtKB=Q86UD3 Q86UD3 MARCHF3 PTHR46065:SF2 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF3 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=24789|UniProtKB=Q6ZSJ8 Q6ZSJ8 C1orf122 PTHR41401:SF1 RGD1559909 RGD1559909 HUMAN|HGNC=26306|UniProtKB=Q658Y4 Q658Y4 FAM91A1 PTHR28441:SF4 PROTEIN FAM91A1 PROTEIN FAM91A1 cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;vesicle localization#GO:0051648;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;vesicle targeting#GO:0006903;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=6467|UniProtKB=Q86UP2 Q86UP2 KTN1 PTHR18864:SF1 KINECTIN KINECTIN HUMAN|HGNC=24662|UniProtKB=Q9NQT4 Q9NQT4 EXOSC5 PTHR11953:SF1 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP46 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;snRNA processing#GO:0016180;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;snRNA metabolic process#GO:0016073;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;exosome (RNase complex)#GO:0000178 exoribonuclease#PC00099 HUMAN|HGNC=1049|UniProtKB=Q96G01 Q96G01 BICD1 PTHR31233:SF3 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D HOMOLOG 1 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;microtubule anchoring#GO:0034453;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of transport#GO:0051049;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of microtubule cytoskeleton organization#GO:0070507;vesicle organization#GO:0016050;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;receptor-mediated endocytosis#GO:0006898;positive regulation of biological process#GO:0048518;regulation of endocytosis#GO:0030100;regulation of organelle organization#GO:0033043;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of receptor-mediated endocytosis#GO:0048259 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=25712|UniProtKB=Q75T13 Q75T13 PGAP1 PTHR15495:SF7 NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED GPI INOSITOL-DEACYLASE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;lipid metabolic process#GO:0006629;cellular localization#GO:0051641;carbohydrate derivative metabolic process#GO:1901135;transport#GO:0006810;glycolipid metabolic process#GO:0006664;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;Golgi vesicle transport#GO:0048193;GPI anchor metabolic process#GO:0006505;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;localization#GO:0051179;glycerolipid metabolic process#GO:0046486;membrane lipid metabolic process#GO:0006643;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;organophosphate metabolic process#GO:0019637;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=2664|UniProtKB=P61803 P61803 DAD1 PTHR10705:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 HUMAN|HGNC=1733|UniProtKB=Q14004 Q14004 CDK13 PTHR24056:SF459 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 13 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;phosphorylation#GO:0016310;DNA-templated transcription, elongation#GO:0006354;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;transcription elongation from RNA polymerase II promoter#GO:0006368;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=25404|UniProtKB=Q4VC44 Q4VC44 FLYWCH1 PTHR31665:SF3 FLYWCH FAMILY MEMBER 2-RELATED FLYWCH-TYPE ZINC FINGER-CONTAINING PROTEIN 1 HUMAN|HGNC=2185|UniProtKB=Q03692 Q03692 COL10A1 PTHR24023:SF880 COLLAGEN ALPHA COLLAGEN ALPHA-1(X) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=20449|UniProtKB=Q6TGC4 Q6TGC4 PADI6 PTHR10837:SF4 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE TYPE-6 HUMAN|HGNC=17615|UniProtKB=Q9BSM1 Q9BSM1 PCGF1 PTHR10825:SF29 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;histone ubiquitination#GO:0016574;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;histone H2A ubiquitination#GO:0033522;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 HUMAN|HGNC=5575|UniProtKB=A0A0B4J1V2 A0A0B4J1V2 IGHV2-26 PTHR23266:SF281 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-26 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=20411|UniProtKB=Q7Z794 Q7Z794 KRT77 PTHR45616:SF24 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 1B HUMAN|HGNC=30830|UniProtKB=Q5TKA1 Q5TKA1 LIN9 PTHR21689:SF2 LIN-9 PROTEIN LIN-9 HOMOLOG heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=2728|UniProtKB=P39656 P39656 DDOST PTHR10830:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 HUMAN|HGNC=14236|UniProtKB=Q96Q80 Q96Q80 DERL3 PTHR11009:SF4 DER1-LIKE PROTEIN, DERLIN DERLIN-3 enzyme binding#GO:0019899;protein binding#GO:0005515;protease binding#GO:0002020;binding#GO:0005488 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;ubiquitin-dependent ERAD pathway#GO:0030433;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane protein complex#GO:0098796;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=29549|UniProtKB=Q8N5J4 Q8N5J4 SPIC PTHR11849:SF17 ETS TRANSCRIPTION FACTOR SPI-C sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 Interleukin signaling pathway#P00036>Ets#P00989 HUMAN|HGNC=20127|UniProtKB=Q86SX3 Q86SX3 TEDC1 PTHR35076:SF1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 1 HUMAN|HGNC=10359|UniProtKB=P83881 P83881 RPL36A PTHR10369:SF6 60S RIBOSOMAL PROTEIN L36A/L44 60S RIBOSOMAL PROTEIN L36A cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=10019|UniProtKB=Q13546 Q13546 RIPK1 PTHR44329:SF6 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>RIP#P00315 HUMAN|HGNC=5905|UniProtKB=P80748 P80748 IGLV3-21 PTHR23267:SF378 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-21 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=29064|UniProtKB=A8K8P3 A8K8P3 SFI1 PTHR22028:SF6 UNCHARACTERIZED PROTEIN SFI1 HOMOLOG HUMAN|HGNC=11856|UniProtKB=P48230 P48230 TM4SF4 PTHR14198:SF15 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 4 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=33752|UniProtKB=Q6UXN7 Q6UXN7 TOMM20L PTHR12430:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 TOMM20-LIKE PROTEIN 1 signal sequence binding#GO:0005048;transmembrane transporter activity#GO:0022857;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;amide transmembrane transporter activity#GO:0042887;protein transmembrane transporter activity#GO:0008320;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein-containing complex assembly#GO:0065003;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;RNA transport#GO:0050658;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;transmembrane transport#GO:0055085;establishment of RNA localization#GO:0051236;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;mitochondrial outer membrane translocase complex assembly#GO:0070096;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 bounding membrane of organelle#GO:0098588;mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;intrinsic component of mitochondrial membrane#GO:0098573;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;integral component of mitochondrial outer membrane#GO:0031307 primary active transporter#PC00068 HUMAN|HGNC=13141|UniProtKB=Q9NQZ8 Q9NQZ8 ZNF71 PTHR24393:SF100 ZINC FINGER PROTEIN ENDOTHELIAL ZINC FINGER PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20072|UniProtKB=Q70EL4 Q70EL4 USP43 PTHR21646:SF20 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 43 cysteine protease#PC00081 HUMAN|HGNC=12659|UniProtKB=Q9UKW4 Q9UKW4 VAV3 PTHR45818:SF1 PROTEIN VAV GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV3 B cell activation#P00010>vav#P00368;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169 HUMAN|HGNC=17|UniProtKB=P22760 P22760 AADAC PTHR23024:SF222 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 deacetylase#PC00087 HUMAN|HGNC=26082|UniProtKB=Q5R3I4 Q5R3I4 TTC38 PTHR16263:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 38 TETRATRICOPEPTIDE REPEAT PROTEIN 38 HUMAN|HGNC=25850|UniProtKB=Q9H871 Q9H871 RMND5A PTHR12170:SF5 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE RMND5A transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29006|UniProtKB=O15027 O15027 SEC16A PTHR13402:SF13 RGPR-RELATED PROTEIN TRANSPORT PROTEIN SEC16A vesicle targeting, to, from or within Golgi#GO:0048199;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;Golgi vesicle budding#GO:0048194;transport#GO:0006810;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;regulation of protein transport#GO:0051223;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of protein localization#GO:0032880;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;protein localization to endoplasmic reticulum#GO:0070972;vesicle localization#GO:0051648;Golgi organization#GO:0007030;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;regulation of cellular localization#GO:0060341;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;COPII-coated vesicle budding#GO:0090114;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 bounding membrane of organelle#GO:0098588;ER to Golgi transport vesicle membrane#GO:0012507;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum exit site#GO:0070971;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;Golgi-associated vesicle membrane#GO:0030660;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=29321|UniProtKB=Q9HCH0 Q9HCH0 NCKAP5L PTHR21740:SF3 NCK-ASSOCIATED PROTEIN 5 NCK-ASSOCIATED PROTEIN 5-LIKE cellular protein complex disassembly#GO:0043624;protein-containing complex disassembly#GO:0032984;microtubule depolymerization#GO:0007019;microtubule cytoskeleton organization#GO:0000226;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;protein-containing complex subunit organization#GO:0043933 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;intracellular organelle#GO:0043229;microtubule#GO:0005874 HUMAN|HGNC=9237|UniProtKB=Q9UBK2 Q9UBK2 PPARGC1A PTHR15528:SF10 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1 PGC-1 -RELATED PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription coactivator activity#GO:0003713;protein binding#GO:0005515;molecular function regulator#GO:0098772;nuclear receptor transcription coactivator activity#GO:0030374;transcription factor binding#GO:0008134 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=4932|UniProtKB=P01889 P01889 HLA-B PTHR16675:SF251 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B ALPHA CHAIN immune response#GO:0006955;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;T cell mediated immunity#GO:0002456;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=18052|UniProtKB=Q9H0F5 Q9H0F5 RNF38 PTHR46171:SF1 GH10160P E3 UBIQUITIN-PROTEIN LIGASE RNF38 HUMAN|HGNC=21092|UniProtKB=Q5T2D2 Q5T2D2 TREML2 PTHR16423:SF3 TREM-LIKE TRANSCRIPT PROTEIN TREM-LIKE TRANSCRIPT 2 PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|HGNC=26693|UniProtKB=Q6ZVT0 Q6ZVT0 TTLL10 PTHR46810:SF1 INACTIVE POLYGLYCYLASE TTLL10 INACTIVE POLYGLYCYLASE TTLL10 HUMAN|HGNC=17638|UniProtKB=A8K0S8 A8K0S8 MEIS3P2 PTHR11850:SF332 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS3-LIKE 1-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;visual system development#GO:0150063;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=945|UniProtKB=O60242 O60242 ADGRB3 PTHR12011:SF40 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR B3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;neurogenesis#GO:0022008;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;cell development#GO:0048468;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;generation of neurons#GO:0048699;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 p53 pathway#P00059>BAI-1#G04699 HUMAN|HGNC=29301|UniProtKB=Q9P206 Q9P206 KIAA1522 PTHR23039:SF6 NANCE-HORAN SYNDROME PROTEIN SIMILAR TO MKIAA1522 PROTEIN cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 HUMAN|HGNC=17921|UniProtKB=Q8TEV9 Q8TEV9 SMCR8 PTHR31334:SF1 SMITH-MAGENIS SYNDROME REGION GENE 8 PROTEIN GUANINE NUCLEOTIDE EXCHANGE PROTEIN SMCR8 Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;Rab GTPase binding#GO:0017137;guanyl-nucleotide exchange factor activity#GO:0005085 protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=14569|UniProtKB=Q9UK76 Q9UK76 JPT1 PTHR34930:SF4 GEO05313P1 JUPITER MICROTUBULE ASSOCIATED HOMOLOG 1 HUMAN|HGNC=18363|UniProtKB=Q8IU54 Q8IU54 IFNL1 PTHR31943:SF14 INTERLEUKIN-28 AND 29 INTERFERON LAMBDA-1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;immune response#GO:0006955;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 interleukin superfamily#PC00128 HUMAN|HGNC=14089|UniProtKB=Q9HCS7 Q9HCS7 XAB2 PTHR11246:SF5 PRE-MRNA SPLICING FACTOR PRE-MRNA-SPLICING FACTOR SYF1 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Lsm2-8 complex#GO:0120115;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974 RNA splicing factor#PC00148 HUMAN|HGNC=17438|UniProtKB=Q7Z7G1 Q7Z7G1 CLNK PTHR14098:SF2 SH2 DOMAIN CONTAINING PROTEIN CYTOKINE-DEPENDENT HEMATOPOIETIC CELL LINKER regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 scaffold/adaptor protein#PC00226 HUMAN|HGNC=21362|UniProtKB=Q8IXS0 Q8IXS0 FAM217A PTHR22145:SF4 SI:CH211-266K22.6 PROTEIN FAM217A HUMAN|HGNC=4317|UniProtKB=P08151 P08151 GLI1 PTHR45718:SF2 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLI1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690 HUMAN|HGNC=30211|UniProtKB=Q709F0 Q709F0 ACAD11 PTHR48083:SF13 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE FAMILY MEMBER 10-RELATED dehydrogenase#PC00092 HUMAN|HGNC=6643|UniProtKB=Q8TAP4 Q8TAP4 LMO3 PTHR45787:SF7 LD11652P LIM DOMAIN ONLY PROTEIN 3 HUMAN|HGNC=2653|UniProtKB=Q9UNU6 Q9UNU6 CYP8B1 PTHR24306:SF0 FAMILY NOT NAMED 7-ALPHA-HYDROXYCHOLEST-4-EN-3-ONE 12-ALPHA-HYDROXYLASE steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 HUMAN|HGNC=18572|UniProtKB=Q6YN16 Q6YN16 HSDL2 PTHR42808:SF3 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 dehydrogenase#PC00092 HUMAN|HGNC=6282|UniProtKB=Q9Y2U2 Q9Y2U2 KCNK7 PTHR11003:SF31 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 7 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=23730|UniProtKB=O60269 O60269 GPRIN2 PTHR15718:SF5 UNCHARACTERIZED G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 2 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=10520|UniProtKB=Q15424 Q15424 SAFB PTHR15683:SF6 SCAFFOLD ATTACHMENT FACTOR B-RELATED SCAFFOLD ATTACHMENT FACTOR B1 sequence-specific DNA binding#GO:0043565;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;RNA metabolic process#GO:0016070;cellular response to steroid hormone stimulus#GO:0071383;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;response to lipid#GO:0033993;biosynthetic process#GO:0009058;cellular response to lipid#GO:0071396;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;intracellular steroid hormone receptor signaling pathway#GO:0030518;cellular response to organic cyclic compound#GO:0071407;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;steroid hormone mediated signaling pathway#GO:0043401;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;response to steroid hormone#GO:0048545;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2603|UniProtKB=O43174 O43174 CYP26A1 PTHR24286:SF101 CYTOCHROME P450 26 CYTOCHROME P450 26A1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;oxidation-reduction process#GO:0055114;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177 HUMAN|HGNC=20086|UniProtKB=Q6P158 Q6P158 DHX57 PTHR18934:SF145 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX57-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA helicase#PC00032 HUMAN|HGNC=2935|UniProtKB=Q9Y5R5 Q9Y5R5 DMRT2 PTHR12322:SF72 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;sex differentiation#GO:0007548;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;reproduction#GO:0000003;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=451|UniProtKB=Q9UHK6 Q9UHK6 AMACR PTHR22923:SF101 CEREBELLIN-RELATED ALPHA-METHYLACYL-COA RACEMASE Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864;Carnitine metabolism#P02733>Carnitine dehydratase#P02866 HUMAN|HGNC=26336|UniProtKB=Q6PEW0 Q6PEW0 PRSS54 PTHR24256:SF528 TRYPTASE-RELATED INACTIVE SERINE PROTEASE 54 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=26162|UniProtKB=Q8WU10 Q8WU10 PYROXD1 PTHR43429:SF2 PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 HUMAN|HGNC=11402|UniProtKB=Q9UPE1 Q9UPE1 SRPK3 PTHR24055:SF100 MITOGEN-ACTIVATED PROTEIN KINASE SRSF PROTEIN KINASE 3 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;regulation of mRNA processing#GO:0050684;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;signaling#GO:0023052;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=5478|UniProtKB=P01876 P01876 IGHA1 PTHR23266:SF68 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY CONSTANT ALPHA 1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=23639|UniProtKB=Q6PGP7 Q6PGP7 TTC37 PTHR15704:SF7 SUPERKILLER 3 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 37 HUMAN|HGNC=14755|UniProtKB=Q8NG92 Q8NG92 OR13H1 PTHR26453:SF76 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13H1 transmembrane signal receptor#PC00197 HUMAN|Ensembl=ENSG00000233954|UniProtKB=A0A096LP55 A0A096LP55 UQCRHL PTHR15336:SF6 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 6-LIKE, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respiratory chain complex III#GO:0005750;membrane-bounded organelle#GO:0043227 reductase#PC00198 HUMAN|HGNC=16041|UniProtKB=Q9ULC0 Q9ULC0 EMCN PTHR15869:SF0 ENDOMUCIN-RELATED ENDOMUCIN HUMAN|HGNC=11767|UniProtKB=O43294 O43294 TGFB1I1 PTHR24216:SF27 PAXILLIN-RELATED TRANSFORMING GROWTH FACTOR BETA-1-INDUCED TRANSCRIPT 1 PROTEIN transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110 cytoplasm#GO:0005737;anchoring junction#GO:0070161;intracellular#GO:0005622;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 Angiogenesis#P00005>Paxillin#P00194;VEGF signaling pathway#P00056>Paxillin#P01418 HUMAN|HGNC=24024|UniProtKB=O60774 O60774 FMO6P PTHR23023:SF81 DIMETHYLANILINE MONOOXYGENASE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 6-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 oxygenase#PC00177 HUMAN|HGNC=23245|UniProtKB=Q6S9Z5 Q6S9Z5 ZNF474 PTHR13555:SF36 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER PROTEIN 474 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23796|UniProtKB=Q8N7X4 Q8N7X4 MAGEB6 PTHR11736:SF139 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B6 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26766|UniProtKB=Q8N957 Q8N957 ANKFN1 PTHR21437:SF3 UNCHARACTERIZED ANKYRIN REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=29920|UniProtKB=Q7Z7K6 Q7Z7K6 CENPV PTHR28620:SF4 CENTROMERE PROTEIN V CENTROMERE PROTEIN V negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;regulation of cell division#GO:0051302;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;regulation of cytokinesis#GO:0032465;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;positive regulation of cytokinesis#GO:0032467;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;positive regulation of cell division#GO:0051781;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;heterochromatin organization#GO:0070828;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;cell division#GO:0051301;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of cell cycle process#GO:0090068;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cytokinesis#GO:0000910;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;membrane fission#GO:0090148;negative regulation of biosynthetic process#GO:0009890;heterochromatin assembly#GO:0031507;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819 HUMAN|HGNC=20593|UniProtKB=Q96JC1 Q96JC1 VPS39 PTHR12894:SF42 CNH DOMAIN CONTAINING VAM6/VPS39-LIKE PROTEIN GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;catabolic process#GO:0009056;vesicle organization#GO:0016050;autophagy#GO:0006914;organelle fusion#GO:0048284;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=25635|UniProtKB=Q8IYT2 Q8IYT2 CMTR2 PTHR16121:SF2 UNCHARACTERIZED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 2 catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;macromolecule methylation#GO:0043414;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4172|UniProtKB=P23771 P23771 GATA3 PTHR10071:SF106 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANS-ACTING T-CELL-SPECIFIC TRANSCRIPTION FACTOR GATA-3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cell fate commitment#GO:0045165;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;epithelium development#GO:0060429;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of epithelial cell differentiation#GO:0030856;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;epithelial cell differentiation#GO:0030855;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=21213|UniProtKB=Q5TH69 Q5TH69 ARFGEF3 PTHR10663:SF344 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 3 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=9508|UniProtKB=P49768 P49768 PSEN1 PTHR10202:SF18 PRESENILIN PRESENILIN-1 binding#GO:0005488;catalytic activity#GO:0003824;cadherin binding#GO:0045296;hydrolase activity#GO:0016787;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;beta-catenin binding#GO:0008013 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;establishment of localization#GO:0051234;regulation of biological quality#GO:0065008;cellular calcium ion homeostasis#GO:0006874;nitrogen compound metabolic process#GO:0006807;negative regulation of programmed cell death#GO:0043069;proteolysis#GO:0006508;apoptotic process#GO:0006915;cell death#GO:0008219;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;membrane protein proteolysis#GO:0033619;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;ion transport#GO:0006811;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;programmed cell death#GO:0012501;cellular nitrogen compound metabolic process#GO:0034641;cation homeostasis#GO:0055080;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;chemical homeostasis#GO:0048878;negative regulation of apoptotic process#GO:0043066;cellular ion homeostasis#GO:0006873;primary metabolic process#GO:0044238;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;metal ion homeostasis#GO:0055065;cellular amide metabolic process#GO:0043603 supramolecular complex#GO:0099080;bounding membrane of organelle#GO:0098588;synapse#GO:0045202;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;apical plasma membrane#GO:0016324;non-membrane-bounded organelle#GO:0043228;intrinsic component of membrane#GO:0031224;lysosome#GO:0005764;mitochondrial envelope#GO:0005740;sarcomere#GO:0030017;plasma membrane region#GO:0098590;distal axon#GO:0150034;envelope#GO:0031975;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;vacuolar membrane#GO:0005774;organelle inner membrane#GO:0019866;cell periphery#GO:0071944;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;axon#GO:0030424;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;lysosomal membrane#GO:0005765;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;lytic vacuole membrane#GO:0098852;mitochondrial inner membrane#GO:0005743;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;cell surface#GO:0009986;intracellular#GO:0005622;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;myofibril#GO:0030016;cilium#GO:0005929;neuromuscular junction#GO:0031594;membrane microdomain#GO:0098857;membrane region#GO:0098589;intraciliary transport particle#GO:0030990;somatodendritic compartment#GO:0036477;Z disc#GO:0030018;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;mitochondrion#GO:0005739;cell cortex#GO:0005938;lytic vacuole#GO:0000323;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;whole membrane#GO:0098805;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cell body#GO:0044297;integral component of plasma membrane#GO:0005887;membrane raft#GO:0045121;growth cone#GO:0030426;I band#GO:0031674;site of polarized growth#GO:0030427 aspartic protease#PC00053 Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Notch signaling pathway#P00045>Presenilin#P01110;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098 HUMAN|HGNC=9587|UniProtKB=P48651 P48651 PTDSS1 PTHR15362:SF15 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 1 transferase#PC00220 HUMAN|HGNC=25413|UniProtKB=Q6UWL2 Q6UWL2 SUSD1 PTHR24051:SF5 SUSHI DOMAIN-CONTAINING PROTEIN 1 SUSHI DOMAIN-CONTAINING PROTEIN 1 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=25416|UniProtKB=Q14CW9 Q14CW9 ATXN7L3 PTHR46367:SF1 ATAXIN-7-LIKE PROTEIN 3 ATAXIN-7-LIKE PROTEIN 3 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;histone deubiquitination#GO:0016578;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear lumen#GO:0031981 HUMAN|HGNC=25524|UniProtKB=Q96PV7 Q96PV7 FAM193B PTHR15109:SF3 AGAP004327-PA PROTEIN FAM193B cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6333|UniProtKB=Q14954 Q14954 KIR2DS1 PTHR11738:SF113 MHC CLASS I NK CELL RECEPTOR KIR2DL PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=10070|UniProtKB=Q9UBF6 Q9UBF6 RNF7 PTHR11210:SF27 RING BOX RING-BOX PROTEIN 2 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=30543|UniProtKB=Q7L8W6 Q7L8W6 DPH6 PTHR12196:SF2 DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN DIPHTHINE--AMMONIA LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 HUMAN|Ensembl=ENSG00000288148|UniProtKB=A0A1W2PRN1 A0A1W2PRN1 ENSG00000288148 PTHR10881:SF62 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8H-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=5985|UniProtKB=Q96F46 Q96F46 IL17RA PTHR15583:SF13 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR A signaling receptor activity#GO:0038023;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;cytokine binding#GO:0019955 transmembrane signal receptor#PC00197 HUMAN|HGNC=8945|UniProtKB=O75830 O75830 SERPINI2 PTHR11461:SF51 SERINE PROTEASE INHIBITOR, SERPIN SERPIN I2 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=10955|UniProtKB=Q92959 Q92959 SLCO2A1 PTHR11388:SF14 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=18595|UniProtKB=Q96JB3 Q96JB3 HIC2 PTHR24399:SF27 ZINC FINGER AND BTB DOMAIN-CONTAINING HYPERMETHYLATED IN CANCER 2 PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=10983|UniProtKB=Q9UJS0 Q9UJS0 SLC25A13 PTHR45678:SF12 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 dicarboxylic acid transport#GO:0006835;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;electron transport chain#GO:0022900;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;anion transport#GO:0006820;respiratory electron transport chain#GO:0022904;oxidation-reduction process#GO:0055114;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152;cellular respiration#GO:0045333;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;generation of precursor metabolites and energy#GO:0006091;ion transport#GO:0006811;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;mitochondrial transport#GO:0006839;localization#GO:0051179;C4-dicarboxylate transport#GO:0015740;organic acid transmembrane transport#GO:1903825 secondary carrier transporter#PC00258 HUMAN|HGNC=9091|UniProtKB=P13797 P13797 PLS3 PTHR19961:SF32 FIMBRIN/PLASTIN PLASTIN-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin filament bundle organization#GO:0061572;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=13165|UniProtKB=Q03938 Q03938 ZNF90 PTHR24384:SF92 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 90 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=2159|UniProtKB=P21554 P21554 CNR1 PTHR22750:SF47 G-PROTEIN COUPLED RECEPTOR CANNABINOID RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Endogenous cannabinoid signaling#P05730>CB1#P05743 HUMAN|HGNC=2400|UniProtKB=P26998 P26998 CRYBB3 PTHR11818:SF13 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B3 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=6462|UniProtKB=P78386 P78386 KRT85 PTHR45616:SF43 FAMILY NOT NAMED KERATIN, TYPE II CUTICULAR HB5 HUMAN|HGNC=27992|UniProtKB=Q86VE3 Q86VE3 SATL1 PTHR10545:SF63 DIAMINE N-ACETYLTRANSFERASE SPERMIDINE/SPERMINE N(1)-ACETYLTRANSFERASE-LIKE PROTEIN 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 HUMAN|HGNC=16002|UniProtKB=Q8TAP9 Q8TAP9 MPLKIP PTHR22446:SF3 UNCHARACTERIZED M-PHASE-SPECIFIC PLK1-INTERACTING PROTEIN HUMAN|HGNC=23716|UniProtKB=O60304 O60304 ZNF500 PTHR23226:SF74 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 500-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11470|UniProtKB=Q7KZ85 Q7KZ85 SUPT6H PTHR10145:SF6 TRANSCRIPTION ELONGATION FACTOR SPT6 TRANSCRIPTION ELONGATION FACTOR SPT6 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of transcription elongation from RNA polymerase II promoter#GO:0032968;nucleosome organization#GO:0034728;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;biosynthetic process#GO:0009058;regulation of DNA-templated transcription, elongation#GO:0032784;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of transcription elongation from RNA polymerase II promoter#GO:0034243;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;transcription elongation from RNA polymerase II promoter#GO:0006368;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=26726|UniProtKB=Q8N9K5 Q8N9K5 ZNF565 PTHR24377:SF70 IP01015P-RELATED ZINC FINGER PROTEIN 565 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=23244|UniProtKB=P49756 P49756 RBM25 PTHR18806:SF4 RBM25 PROTEIN RNA-BINDING PROTEIN 25 HUMAN|HGNC=4617|UniProtKB=P49841 P49841 GSK3B PTHR24057:SF8 GLYCOGEN SYNTHASE KINASE-3 ALPHA GLYCOGEN SYNTHASE KINASE-3 BETA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;beta-catenin binding#GO:0008013;protein kinase activity#GO:0004672 cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular response to hormone stimulus#GO:0032870;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;cytoskeleton organization#GO:0007010;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;negative regulation of cell communication#GO:0010648;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;response to organonitrogen compound#GO:0010243;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell-cell signaling by wnt#GO:0198738;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;apoptotic signaling pathway#GO:0097190;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of Wnt signaling pathway#GO:0030178;regulation of microtubule-based process#GO:0032886;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;signal transduction#GO:0007165;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;regulation of signaling#GO:0023051;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cellular response to nitrogen compound#GO:1901699;cell differentiation#GO:0030154;system development#GO:0048731;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to peptide#GO:1901652;regulation of microtubule cytoskeleton organization#GO:0070507;cell death#GO:0008219;neuron differentiation#GO:0030182;cellular response to insulin stimulus#GO:0032869;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;response to organic substance#GO:0010033;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;regulation of canonical Wnt signaling pathway#GO:0060828;cell development#GO:0048468;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;extrinsic apoptotic signaling pathway#GO:0097191;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;negative regulation of canonical Wnt signaling pathway#GO:0090090;generation of neurons#GO:0048699 synapse#GO:0045202;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Glycogen Synthase Kinase-3Beta#P01441;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;PI3 kinase pathway#P00048>GSK3#P01181;Interleukin signaling pathway#P00036>GSK3#P00976;Ras Pathway#P04393>GSK3#P04546;Angiogenesis#P00005>GSK3beta#P00211;Cadherin signaling pathway#P00012>GSK3beta#P00477;Hedgehog signaling pathway#P00025>GSK3#P00692;CCKR signaling map#P06959>GSK3beta#P07199;Alzheimer disease-presenilin pathway#P00004>GSK-3beta#P00175;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GSK#P00714;Gonadotropin-releasing hormone receptor pathway#P06664>GSK3#P06827;PDGF signaling pathway#P00047>GSK3#P01153 HUMAN|HGNC=17274|UniProtKB=Q14134 Q14134 TRIM29 PTHR25465:SF7 FAMILY NOT NAMED TRIPARTITE MOTIF-CONTAINING PROTEIN 29 HUMAN|HGNC=19986|UniProtKB=P99999 P99999 CYCS PTHR11961:SF29 CYTOCHROME C CYTOCHROME C nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;regulation of protein metabolic process#GO:0051246;proton transmembrane transport#GO:1902600;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ribose phosphate metabolic process#GO:0019693;proteolysis#GO:0006508;oxidation-reduction process#GO:0055114;cellular protein metabolic process#GO:0044267;positive regulation of peptidase activity#GO:0010952;purine nucleotide metabolic process#GO:0006163;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;aerobic electron transport chain#GO:0019646;positive regulation of molecular function#GO:0044093;cation transport#GO:0006812;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;positive regulation of programmed cell death#GO:0043068;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;cell death#GO:0008219;protein metabolic process#GO:0019538;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;regulation of programmed cell death#GO:0043067;heterocycle metabolic process#GO:0046483;regulation of proteolysis#GO:0030162;transmembrane transport#GO:0055085;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;positive regulation of protein metabolic process#GO:0051247;oxidative phosphorylation#GO:0006119;regulation of cell death#GO:0010941;nucleoside triphosphate biosynthetic process#GO:0009142;positive regulation of cell death#GO:0010942;ribonucleoside triphosphate metabolic process#GO:0009199;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;inorganic cation transmembrane transport#GO:0098662;positive regulation of cellular metabolic process#GO:0031325;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;positive regulation of proteolysis#GO:0045862;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;establishment of localization#GO:0051234;ATP metabolic process#GO:0046034;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;apoptotic process#GO:0006915;purine-containing compound metabolic process#GO:0072521;regulation of hydrolase activity#GO:0051336;positive regulation of biological process#GO:0048518;purine nucleoside triphosphate biosynthetic process#GO:0009145;organic substance metabolic process#GO:0071704;aerobic respiration#GO:0009060;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;ribonucleoside triphosphate biosynthetic process#GO:0009201;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;ribonucleotide biosynthetic process#GO:0009260;aromatic compound biosynthetic process#GO:0019438;regulation of endopeptidase activity#GO:0052548;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;transport#GO:0006810;purine-containing compound biosynthetic process#GO:0072522;cation transmembrane transport#GO:0098655;positive regulation of metabolic process#GO:0009893;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;regulation of apoptotic process#GO:0042981;ion transport#GO:0006811;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;energy coupled proton transport, down electrochemical gradient#GO:0015985;purine nucleoside triphosphate metabolic process#GO:0009144;positive regulation of cellular protein metabolic process#GO:0032270;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide biosynthetic process#GO:0009152 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;mitochondrial intermembrane space#GO:0005758;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 Apoptosis signaling pathway#P00006>Cytochrome C#P00322;ATP synthesis#P02721>Cyt C#P02798 HUMAN|HGNC=19719|UniProtKB=Q9HBX8 Q9HBX8 LGR6 PTHR45836:SF22 SLIT HOMOLOG LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 6 carbohydrate derivative binding#GO:0097367;binding#GO:0005488;heparin binding#GO:0008201;protein binding#GO:0005515;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;growth#GO:0040007;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;regulation of cell growth#GO:0001558;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cell growth#GO:0016049;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 HUMAN|HGNC=16179|UniProtKB=P59827 P59827 BPIFB4 PTHR46019:SF4 BPI FOLD-CONTAINING FAMILY B MEMBER 4-RELATED BPI FOLD-CONTAINING FAMILY B MEMBER 4 HUMAN|HGNC=14083|UniProtKB=Q96JP2 Q96JP2 MYO15B PTHR22692:SF16 MYOSIN VII, XV UNCONVENTIONAL MYOSIN-XVB actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=1527|UniProtKB=Q03135 Q03135 CAV1 PTHR10844:SF18 CAVEOLIN CAVEOLIN-1 ion channel binding#GO:0044325;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;plasma membrane organization#GO:0007009;endomembrane system organization#GO:0010256;cell population proliferation#GO:0008283;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;epithelial cell proliferation#GO:0050673;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;endothelial cell proliferation#GO:0001935;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of cell population proliferation#GO:0008285;phosphorylation#GO:0016310;negative regulation of transferase activity#GO:0051348;protein metabolic process#GO:0019538;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;regulation of cell population proliferation#GO:0042127;negative regulation of phosphorus metabolic process#GO:0010563;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 plasma membrane raft#GO:0044853;perinuclear region of cytoplasm#GO:0048471;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intrinsic component of plasma membrane#GO:0031226;membrane raft#GO:0045121;membrane region#GO:0098589;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>Caveolin#P00918;Gonadotropin-releasing hormone receptor pathway#P06664>Caveolin-1#P06763 HUMAN|HGNC=5034|UniProtKB=Q99729 Q99729 HNRNPAB PTHR48033:SF1 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A/B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=29023|UniProtKB=Q6PFW1 Q6PFW1 PPIP5K1 PTHR12750:SF11 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;cellular carbohydrate metabolic process#GO:0044262;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotide kinase#PC00172 HUMAN|HGNC=11326|UniProtKB=P51571 P51571 SSR4 PTHR12731:SF1 TRANSLOCON-ASSOCIATED PROTEIN, DELTA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT DELTA cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=3668|UniProtKB=P61328 P61328 FGF12 PTHR11486:SF17 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 12 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=30492|UniProtKB=Q8N9W5 Q8N9W5 DNAAF3 PTHR22118:SF14 DYNEIN ASSEMBLY FACTOR 3, AXONEMAL DYNEIN ASSEMBLY FACTOR 3, AXONEMAL chaperone#PC00072 HUMAN|HGNC=15356|UniProtKB=Q8NH43 Q8NH43 OR4L1 PTHR48002:SF59 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4L1 transmembrane signal receptor#PC00197 HUMAN|HGNC=13083|UniProtKB=Q9ULJ3 Q9ULJ3 ZBTB21 PTHR24408:SF18 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 21 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6869|UniProtKB=Q14244 Q14244 MAP7 PTHR15073:SF4 MICROTUBULE-ASSOCIATED PROTEIN ENSCONSIN microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=23334|UniProtKB=Q5VT79 Q5VT79 ANXA8L1 PTHR10502:SF133 ANNEXIN ANNEXIN A8-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;endosomal transport#GO:0016197;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of lipase activity#GO:0060191;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of phospholipase activity#GO:0010517;endomembrane system organization#GO:0010256;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;endosome organization#GO:0007032;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;vesicle organization#GO:0016050;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of endopeptidase activity#GO:0052548;intracellular transport#GO:0046907;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calcium-binding protein#PC00060 HUMAN|HGNC=5644|UniProtKB=S4R460 S4R460 IGHV3OR16-9 PTHR23266:SF298 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=10564|UniProtKB=O15127 O15127 SCAMP2 PTHR10687:SF7 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 2 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 HUMAN|HGNC=4897|UniProtKB=O14964 O14964 HGS PTHR46275:SF1 HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE HUMAN|HGNC=33268|UniProtKB=Q8NHU0 Q8NHU0 CT45A3 PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED CANCER/TESTIS ANTIGEN FAMILY 45 MEMBER A1-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 RNA helicase#PC00032 HUMAN|HGNC=9564|UniProtKB=Q15008 Q15008 PSMD6 PTHR14145:SF1 26S PROTESOME SUBUNIT 6 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 HUMAN|HGNC=19761|UniProtKB=Q8WXA3 Q8WXA3 RUFY2 PTHR45956:SF3 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=6696|UniProtKB=O75096 O75096 LRP4 PTHR24270:SF5 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 4 apolipoprotein#PC00052 Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 HUMAN|HGNC=830|UniProtKB=P06576 P06576 ATP5F1B PTHR15184:SF60 ATP SYNTHASE ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;ion channel activity#GO:0005216;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;pyrophosphatase activity#GO:0016462;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular localization#GO:0051641;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;mitochondrial transmembrane transport#GO:1990542;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;intracellular transport#GO:0046907;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial transport#GO:0006839;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;establishment of localization in cell#GO:0051649;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 ATP synthesis#P02721>F1 beta#P02794 HUMAN|HGNC=15965|UniProtKB=Q9NR90 Q9NR90 DAZ3 PTHR11176:SF8 BOULE-RELATED DELETED IN AZOOSPERMIA PROTEIN 1-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of translational initiation#GO:0045948;gene expression#GO:0010467;regulation of translational initiation#GO:0006446;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;translational initiation#GO:0006413;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=32468|UniProtKB=O75373 O75373 ZNF737 PTHR24384:SF128 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 737 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=32322|UniProtKB=Q7RTU7 Q7RTU7 SCX PTHR23349:SF5 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR SCLERAXIS sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=10620|UniProtKB=O00585 O00585 CCL21 PTHR12015:SF72 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 21 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=4647|UniProtKB=P52657 P52657 GTF2A2 PTHR10966:SF5 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription regulator activity#GO:0140110;RNA polymerase II general transcription initiation factor activity#GO:0016251;transcription factor binding#GO:0008134;binding#GO:0005488;TBP-class protein binding#GO:0017025 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 HUMAN|HGNC=51509|UniProtKB=A0A494C0Z2 A0A494C0Z2 SPDYE13 PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=13408|UniProtKB=Q14690 Q14690 PDCD11 PTHR23270:SF10 PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5 PROTEIN RRP5 HOMOLOG nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=2441|UniProtKB=P0DML3 P0DML3 CSH2 PTHR11417:SF67 SOMATOTROPIN,PROLACTIN CHORIONIC SOMATOMAMMOTROPIN HORMONE 1-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;response to extracellular stimulus#GO:0009991;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to hormone stimulus#GO:0032870;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of receptor signaling pathway via STAT#GO:1904894;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of growth#GO:0045927;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;tyrosine phosphorylation of STAT protein#GO:0007260;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to peptide hormone#GO:0043434;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;growth#GO:0040007;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of growth#GO:0040008;regulation of receptor signaling pathway via STAT#GO:1904892;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;response to nutrient levels#GO:0031667;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to hormone#GO:0009725;receptor signaling pathway via STAT#GO:0097696;peptidyl-tyrosine modification#GO:0018212;regulation of macromolecule metabolic process#GO:0060255;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 HUMAN|HGNC=5249|UniProtKB=Q9UBY9 Q9UBY9 HSPB7 PTHR46907:SF2 HEAT SHOCK PROTEIN BETA-7-RELATED HEAT SHOCK PROTEIN BETA-7 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6835|UniProtKB=P78559 P78559 MAP1A PTHR13843:SF6 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1A cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;actin binding#GO:0003779;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cellular protein complex disassembly#GO:0043624;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;dendrite development#GO:0016358;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;cell morphogenesis involved in differentiation#GO:0000904;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;protein depolymerization#GO:0051261;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cytosol#GO:0005829;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cell body#GO:0044297;intracellular#GO:0005622;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;microtubule#GO:0005874;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=2955|UniProtKB=O96015 O96015 DNAL4 PTHR11886:SF2 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 4, AXONEMAL protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of hydrolase activity#GO:0051345 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=2383|UniProtKB=O43186 O43186 CRX PTHR45793:SF7 HOMEOBOX PROTEIN CONE-ROD HOMEOBOX PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=18083|UniProtKB=Q9HBA0 Q9HBA0 TRPV4 PTHR10582:SF4 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 4 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;positive regulation of cytosolic calcium ion concentration#GO:0007204;inorganic ion transmembrane transport#GO:0098660;regulation of biological process#GO:0050789;actin filament-based process#GO:0030029;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cytoskeleton organization#GO:0007010;response to abiotic stimulus#GO:0009628;cellular cation homeostasis#GO:0030003;cellular response to osmotic stress#GO:0071470;calcium ion transmembrane transport#GO:0070588;cell communication#GO:0007154;cellular component organization#GO:0016043;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;calcium ion import#GO:0070509;cellular component organization or biogenesis#GO:0071840;calcium ion transport into cytosol#GO:0060402;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;regulation of cellular process#GO:0050794;response to osmotic stress#GO:0006970;calcium ion transmembrane import into cytosol#GO:0097553;cellular response to stress#GO:0033554;metal ion homeostasis#GO:0055065;cellular response to environmental stimulus#GO:0104004;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;transport#GO:0006810;cytosolic calcium ion transport#GO:0060401;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;cellular response to abiotic stimulus#GO:0071214;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular divalent inorganic cation homeostasis#GO:0072503;signaling#GO:0023052;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;cellular response to chemical stimulus#GO:0070887;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;response to stimulus#GO:0050896;response to chemical#GO:0042221;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;actin cytoskeleton organization#GO:0030036 intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=20879|UniProtKB=Q8WXD9 Q8WXD9 CASKIN1 PTHR24177:SF12 CASKIN CASKIN-1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11634|UniProtKB=P15884 P15884 TCF4 PTHR11793:SF10 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 CCKR signaling map#P06959>TCF7L2#P07126 HUMAN|HGNC=1719|UniProtKB=O60729 O60729 CDC14B PTHR23339:SF74 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14B phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;regulation of mitotic nuclear division#GO:0007088;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;regulation of exit from mitosis#GO:0007096;nuclear division#GO:0000280;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;axoneme assembly#GO:0035082;regulation of cell division#GO:0051302;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;positive regulation of biological process#GO:0048518;regulation of cytokinesis#GO:0032465;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;positive regulation of cytokinesis#GO:0032467;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;cell cycle phase transition#GO:0044770;intraciliary transport#GO:0042073;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;cell cycle arrest#GO:0007050;positive regulation of cell division#GO:0051781;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;cell division#GO:0051301;negative regulation of biological process#GO:0048519;mitotic cell cycle phase transition#GO:0044772;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle process#GO:1903047;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;positive regulation of cell cycle process#GO:0090068;cytoskeleton-dependent intracellular transport#GO:0030705;mitotic nuclear division#GO:0140014;protein localization to organelle#GO:0033365;negative regulation of cellular process#GO:0048523;cytokinesis#GO:0000910;membrane fission#GO:0090148;vesicle localization#GO:0051648;regulation of nuclear division#GO:0051783;negative regulation of mitotic cell cycle#GO:0045930;intraciliary transport involved in cilium assembly#GO:0035735;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;stereocilium#GO:0032420;non-membrane-bounded organelle#GO:0043228;kinocilium#GO:0060091;stereocilium bundle#GO:0032421;actin cytoskeleton#GO:0015629;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;membrane-enclosed lumen#GO:0031974;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;organelle lumen#GO:0043233;cluster of actin-based cell projections#GO:0098862;nucleus#GO:0005634;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;centriole#GO:0005814;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;neuron projection#GO:0043005;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;nuclear lumen#GO:0031981;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 protein phosphatase#PC00195 HUMAN|HGNC=22203|UniProtKB=O94880 O94880 PHF14 PTHR13793:SF150 PHD FINGER PROTEINS PHD FINGER PROTEIN 14 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein binding#GO:0005515;histone binding#GO:0042393;N-acyltransferase activity#GO:0016410 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;histone H3 acetylation#GO:0043966;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;histone acetylation#GO:0016573;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;peptidyl-lysine modification#GO:0018205;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 zinc finger transcription factor#PC00244 HUMAN|HGNC=11249|UniProtKB=P16150 P16150 SPN PTHR35265:SF1 LEUKOSIALIN LEUKOSIALIN heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;positive regulation of cytokine production#GO:0001819;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;regulation of cytokine biosynthetic process#GO:0042035;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;tumor necrosis factor production#GO:0032640;biosynthetic process#GO:0009058;cytokine production#GO:0001816;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;response to bacterium#GO:0009617;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=16226|UniProtKB=Q5TG30 Q5TG30 ARHGAP40 PTHR14963:SF4 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 40 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;regulation of signaling#GO:0023051;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;intracellular signal transduction#GO:0035556;regulation of protein polymerization#GO:0032271;signaling#GO:0023052;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cellular response to stimulus#GO:0051716;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of small GTPase mediated signal transduction#GO:0051056;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 HUMAN|HGNC=18233|UniProtKB=Q8NDB2 Q8NDB2 BANK1 PTHR16267:SF13 BANK1/PIK3AP1 FAMILY MEMBER B-CELL SCAFFOLD PROTEIN WITH ANKYRIN REPEATS enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;regulation of signal transduction#GO:0009966;regulation of immune system process#GO:0002682;B cell activation#GO:0042113;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;leukocyte activation#GO:0045321;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein kinase B signaling#GO:0043491;negative regulation of signal transduction#GO:0009968;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250;regulation of protein kinase B signaling#GO:0051896 HUMAN|HGNC=4115|UniProtKB=P54803 P54803 GALC PTHR15172:SF1 GALACTOCEREBROSIDASE GALACTOCEREBROSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 galactosidase#PC00104 HUMAN|HGNC=21083|UniProtKB=Q9BWJ5 Q9BWJ5 SF3B5 PTHR20978:SF0 SPLICING FACTOR 3B SUBUNIT 5 SPLICING FACTOR 3B SUBUNIT 5 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=14841|UniProtKB=Q8NH85 Q8NH85 OR5R1 PTHR48018:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5R1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=13478|UniProtKB=Q7Z3V4 Q7Z3V4 UBE3B PTHR45700:SF3 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3B ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 HUMAN|HGNC=18593|UniProtKB=Q8NG66 Q8NG66 NEK11 PTHR43671:SF24 SERINE/THREONINE-PROTEIN KINASE NEK SERINE/THREONINE-PROTEIN KINASE NEK11 negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cell cycle process#GO:0022402;mitotic cell cycle process#GO:1903047;intra-S DNA damage checkpoint#GO:0031573;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;cell cycle checkpoint#GO:0000075;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;mitotic DNA damage checkpoint#GO:0044773;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;cellular response to DNA damage stimulus#GO:0006974;mitotic DNA integrity checkpoint#GO:0044774;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346 membrane-enclosed lumen#GO:0031974;microtubule organizing center#GO:0005815;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=10452|UniProtKB=P31350 P31350 RRM2 PTHR23409:SF20 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909;p53 pathway#P00059>R2#G04692 HUMAN|HGNC=25613|UniProtKB=Q69YN2 Q69YN2 CWF19L1 PTHR12072:SF4 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682 HUMAN|HGNC=15687|UniProtKB=O75563 O75563 SKAP2 PTHR15129:SF2 SRC-ASSOCIATED ADAPTOR PROTEIN SRC KINASE-ASSOCIATED PHOSPHOPROTEIN 2 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3571|UniProtKB=O60488 O60488 ACSL4 PTHR43272:SF22 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 4 ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;neurogenesis#GO:0022008;sulfur compound metabolic process#GO:0006790;developmental process#GO:0032502;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;neuron differentiation#GO:0030182;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;long-chain fatty acid metabolic process#GO:0001676;cellular developmental process#GO:0048869;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;fatty acid derivative metabolic process#GO:1901568;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;generation of neurons#GO:0048699;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 lipid droplet#GO:0005811;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 ligase#PC00142 HUMAN|HGNC=25183|UniProtKB=Q8TC57 Q8TC57 M1AP PTHR28642:SF1 MEIOSIS 1 ARREST PROTEIN MEIOSIS 1 ARREST PROTEIN male gamete generation#GO:0048232;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;multi-organism process#GO:0051704;chromosome segregation#GO:0007059;meiotic chromosome separation#GO:0051307;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell cycle#GO:0007049;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;male meiotic nuclear division#GO:0007140;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609 HUMAN|HGNC=7737|UniProtKB=P12036 P12036 NEFH PTHR23214:SF1 NEUROFILAMENT TRIPLET H PROTEIN NEUROFILAMENT HEAVY POLYPEPTIDE HUMAN|HGNC=31748|UniProtKB=Q6XE38 Q6XE38 SCGB1D4 PTHR11332:SF6 SECRETOGLOBIN FAMILY 1D SECRETOGLOBIN FAMILY 1D MEMBER 4 transfer/carrier protein#PC00219 HUMAN|HGNC=23355|UniProtKB=Q9NTK1 Q9NTK1 DEPP1 PTHR15426:SF6 PROTEIN DEPP1 PROTEIN DEPP1 process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;biological regulation#GO:0065007;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;cellular catabolic process#GO:0044248;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=8154|UniProtKB=P41145 P41145 OPRK1 PTHR24229:SF1 NEUROPEPTIDES RECEPTOR KAPPA-TYPE OPIOID RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of pain#GO:0019233;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Opioid prodynorphin pathway#P05916>Kappa Receptor#P05998 HUMAN|HGNC=11373|UniProtKB=P52823 P52823 STC1 PTHR11245:SF1 STANNIOCALCIN STANNIOCALCIN-1 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 HUMAN|HGNC=12640|UniProtKB=Q9P2Y5 Q9P2Y5 UVRAG PTHR15157:SF5 UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284;protein-containing complex subunit organization#GO:0043933 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=12586|UniProtKB=P22695 P22695 UQCRC2 PTHR11851:SF49 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL metalloprotease#PC00153 HUMAN|HGNC=2025|UniProtKB=P51798 P51798 CLCN7 PTHR11689:SF136 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)/CL(-) EXCHANGE TRANSPORTER 7 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ion channel#PC00133 HUMAN|HGNC=13188|UniProtKB=Q05996 Q05996 ZP2 PTHR23343:SF4 ZONA PELLUCIDA SPERM-BINDING PROTEIN ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 HUMAN|Ensembl=ENSG00000284298|UniProtKB=A0A1B0GW55 A0A1B0GW55 ENSG00000284298 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=10963|UniProtKB=O15245 O15245 SLC22A1 PTHR24064:SF291 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 1 ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;organic substance transport#GO:0071702;cation transport#GO:0006812;establishment of localization#GO:0051234;organic cation transport#GO:0015695;ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258 HUMAN|HGNC=24061|UniProtKB=Q86UN6 Q86UN6 AKAP14 PTHR35075:SF1 A-KINASE ANCHOR PROTEIN 14 A-KINASE ANCHOR PROTEIN 14 protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;binding#GO:0005488 protein-containing complex#GO:0032991;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20210|UniProtKB=Q9NWQ4 Q9NWQ4 GPATCH2L PTHR14195:SF3 G PATCH DOMAIN CONTAINING PROTEIN 2 G PATCH DOMAIN-CONTAINING PROTEIN 2-LIKE RNA metabolism protein#PC00031 HUMAN|HGNC=9045|UniProtKB=Q6DJT9 Q6DJT9 PLAG1 PTHR24388:SF69 ZINC FINGER PROTEIN ZINC FINGER PROTEIN PLAG1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11196|UniProtKB=O60248 O60248 SOX15 PTHR10270:SF45 SOX TRANSCRIPTION FACTOR PROTEIN SOX-15 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=24487|UniProtKB=A6NI79 A6NI79 CCDC69 PTHR24200:SF6 TOUCAN, ISOFORM A COILED-COIL DOMAIN-CONTAINING PROTEIN 69 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=33626|UniProtKB=A6NGY1 A6NGY1 FRG2C PTHR31883:SF1 PROTEIN FRG2-RELATED PROTEIN FRG2-LIKE-2 HUMAN|HGNC=6463|UniProtKB=O43790 O43790 KRT86 PTHR45616:SF7 FAMILY NOT NAMED KERATIN, TYPE II CUTICULAR HB6 HUMAN|HGNC=3232|UniProtKB=O75095 O75095 MEGF6 PTHR24035:SF137 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 6 extracellular matrix protein#PC00102 HUMAN|HGNC=4181|UniProtKB=Q92538 Q92538 GBF1 PTHR10663:SF316 GUANYL-NUCLEOTIDE EXCHANGE FACTOR GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=13247|UniProtKB=Q9NZB2 Q9NZB2 FAM120A PTHR15976:SF14 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PPAR-GAMMA-LIKE PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=8282|UniProtKB=P47881 P47881 OR3A1 PTHR48001:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A1 transmembrane signal receptor#PC00197 HUMAN|HGNC=6544|UniProtKB=P07864 P07864 LDHC PTHR43128:SF5 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE C CHAIN oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092 HUMAN|HGNC=30698|UniProtKB=Q6PIZ9 Q6PIZ9 TRAT1 PTHR15951:SF2 T-CELL RECEPTOR-ASSOCIATED TRANSMEMBRANE ADAPTER 1 T-CELL RECEPTOR-ASSOCIATED TRANSMEMBRANE ADAPTER 1 defense/immunity protein#PC00090 HUMAN|HGNC=21064|UniProtKB=Q64LD2 Q64LD2 WDR25 PTHR42968:SF4 WD REPEAT-CONTAINING WD REPEAT-CONTAINING PROTEIN 25 scaffold/adaptor protein#PC00226 HUMAN|HGNC=44197|UniProtKB=F5H4B4 F5H4B4 FAM227A PTHR33560:SF1 PROTEIN FAM227B PROTEIN FAM227A HUMAN|HGNC=13932|UniProtKB=Q5SRR4 Q5SRR4 LY6G5C PTHR14909:SF6 LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G5C LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G5C external side of plasma membrane#GO:0009897;leaflet of membrane bilayer#GO:0097478;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=19164|UniProtKB=Q9Y3M8 Q9Y3M8 STARD13 PTHR12659:SF6 RHO-TYPE GTPASE ACTIVATING PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 13 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;Rho protein signal transduction#GO:0007266;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;actin cytoskeleton organization#GO:0030036;signaling#GO:0023052;regulation of Ras protein signal transduction#GO:0046578 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=4538|UniProtKB=Q9BY21 Q9BY21 GPR87 PTHR24233:SF8 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 87 nucleotide binding#GO:0000166;signaling receptor activity#GO:0038023;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=26742|UniProtKB=Q8N9F0 Q8N9F0 NAT8L PTHR13947:SF11 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLASPARTATE SYNTHETASE transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 acetyltransferase#PC00038 HUMAN|HGNC=29045|UniProtKB=Q9NUA8 Q9NUA8 ZBTB40 PTHR24394:SF0 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 40 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29513|UniProtKB=O60306 O60306 AQR PTHR10887:SF5 DNA2/NAM7 HELICASE FAMILY RNA HELICASE AQUARIUS nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=24579|UniProtKB=O75838 O75838 CIB2 PTHR45791:SF5 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 2 HUMAN|HGNC=30694|UniProtKB=Q86SM8 Q86SM8 MRGPRE PTHR11334:SF26 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MEMBER E signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=17118|UniProtKB=Q9H0A6 Q9H0A6 RNF32 PTHR14991:SF0 RING FINGER PROTEIN 32 RING FINGER PROTEIN 32 HUMAN|HGNC=22917|UniProtKB=Q9H5U6 Q9H5U6 ZCCHC4 PTHR13493:SF3 ZINC FINGER CCHC DOMAIN-CONTAINING RRNA N6-ADENOSINE-METHYLTRANSFERASE ZCCHC4 catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;RNA methylation#GO:0001510 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 HUMAN|HGNC=1249|UniProtKB=Q9ULW0 Q9ULW0 TPX2 PTHR14326:SF44 TARGETING PROTEIN FOR XKLP2 TARGETING PROTEIN FOR XKLP2 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=4416|UniProtKB=O15228 O15228 GNPAT PTHR12563:SF17 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;triglyceride metabolic process#GO:0006641;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;fatty acid metabolic process#GO:0006631;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;microbody membrane#GO:0031903;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=11538|UniProtKB=Q92750 Q92750 TAF4B PTHR15138:SF17 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4B nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;RNA polymerase II general transcription initiation factor activity#GO:0016251 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=25929|UniProtKB=Q96JY0 Q96JY0 MAEL PTHR21358:SF4 PROTEIN MAELSTROM HOMOLOG PROTEIN MAELSTROM HOMOLOG sequence-specific DNA binding#GO:0043565;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;male gamete generation#GO:0048232;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;spermatogenesis#GO:0007283;reproductive process#GO:0022414;male meiotic nuclear division#GO:0007140;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;cellular process involved in reproduction in multicellular organism#GO:0022412;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;multi-organism process#GO:0051704;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=3693|UniProtKB=Q8N441 Q8N441 FGFRL1 PTHR19890:SF10 FIBROBLAST GROWTH FACTOR RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR-LIKE 1 tyrosine protein kinase receptor#PC00233 HUMAN|HGNC=7863|UniProtKB=Q13423 Q13423 NNT PTHR10160:SF22 NAD(P) TRANSHYDROGENASE NAD(P) TRANSHYDROGENASE, MITOCHONDRIAL nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;NADP binding#GO:0050661;oxidoreductase activity#GO:0016491 oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;NADP metabolic process#GO:0006739;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092 HUMAN|HGNC=2554|UniProtKB=Q13619 Q13619 CUL4A PTHR11932:SF68 CULLIN CULLIN-4A transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular response to stress#GO:0033554;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=15996|UniProtKB=Q9UK55 Q9UK55 SERPINA10 PTHR11461:SF191 SERINE PROTEASE INHIBITOR, SERPIN PROTEIN Z-DEPENDENT PROTEASE INHIBITOR serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>ZPI#P00425 HUMAN|HGNC=24948|UniProtKB=Q8TEK3 Q8TEK3 DOT1L PTHR21451:SF0 HISTONE H3 METHYLTRANSFERASE HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 DNA repair#GO:0006281;negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;chromatin silencing at telomere#GO:0006348;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;DNA damage checkpoint#GO:0000077;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=25913|UniProtKB=Q96K49 Q96K49 TMEM87B PTHR21229:SF16 LUNG SEVEN TRANSMEMBRANE RECEPTOR TRANSMEMBRANE PROTEIN 87B localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=23470|UniProtKB=A6NFZ4 A6NFZ4 FAM24A PTHR35860:SF1 PROTEIN FAM24B PROTEIN FAM24A HUMAN|HGNC=1698|UniProtKB=P11912 P11912 CD79A PTHR14334:SF1 B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN ALPHA CHAIN immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;animal organ development#GO:0048513;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;B cell receptor signaling pathway#GO:0050853;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of immune response#GO:0050778;hemopoiesis#GO:0030097;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;B cell activation#GO:0042113;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;immune system development#GO:0002520;regulation of immune response#GO:0050776;multicellular organism development#GO:0007275;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;B cell differentiation#GO:0030183;lymphocyte differentiation#GO:0030098;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 B cell activation#P00010>Ig-alpha#P00399 HUMAN|HGNC=10959|UniProtKB=Q9Y6L6 Q9Y6L6 SLCO1B1 PTHR11388:SF82 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B1 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=406|UniProtKB=P30038 P30038 ALDH4A1 PTHR14516:SF3 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=15352|UniProtKB=Q8NGD5 Q8NGD5 OR4K14 PTHR48002:SF115 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K14 transmembrane signal receptor#PC00197 HUMAN|HGNC=23302|UniProtKB=Q2TB90 Q2TB90 HKDC1 PTHR19443:SF28 HEXOKINASE HEXOKINASE HKDC1 transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;cellular homeostasis#GO:0019725;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;chemical homeostasis#GO:0048878;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;cellular chemical homeostasis#GO:0055082;glycolytic process#GO:0006096;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 Pentose phosphate pathway#P02762>Hexokinase#P03079;Glycolysis#P00024>Hexokinase#P00677;Fructose galactose metabolism#P02744>Hexokinase#P02966 HUMAN|HGNC=21487|UniProtKB=Q8TC41 Q8TC41 RNF217 PTHR11685:SF338 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF217-RELATED ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=12177|UniProtKB=A0A0K0K1A3 A0A0K0K1A3 TRBV10-1 PTHR23268:SF80 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 10-1-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=17102|UniProtKB=Q92619 Q92619 ARHGAP45 PTHR15228:SF18 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 45 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=28838|UniProtKB=Q68G74 Q68G74 LHX8 PTHR24208:SF117 LIM/HOMEOBOX PROTEIN LHX LIM/HOMEOBOX PROTEIN LHX8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;central nervous system neuron differentiation#GO:0021953;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;forebrain development#GO:0030900;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;neuron development#GO:0048666;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=22429|UniProtKB=Q8TAQ9 Q8TAQ9 SUN3 PTHR12911:SF24 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 3 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;nuclear envelope organization#GO:0006998;cellular process#GO:0009987 envelope#GO:0031975;membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=16760|UniProtKB=Q9H9Q2 Q9H9Q2 COPS7B PTHR15350:SF8 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 SIGNALOSOME COMPLEX SUBUNIT 7B protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229 HUMAN|HGNC=4085|UniProtKB=P78334 P78334 GABRE PTHR18945:SF397 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT EPSILON signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;cell junction#GO:0030054;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=26924|UniProtKB=Q6P2C0 Q6P2C0 WDR93 PTHR12219:SF17 NADH-UBIQUINONE OXIDOREDUCTASE WD REPEAT-CONTAINING PROTEIN 93 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=12535|UniProtKB=P35503 P35503 UGT1A3 PTHR48050:SF12 STEROL 3-BETA-GLUCOSYLTRANSFERASE UDP-GLUCURONOSYLTRANSFERASE 1A3-RELATED glycosyltransferase#PC00111 Nicotine degradation#P05914>UGT1A4#P05982 HUMAN|HGNC=15945|UniProtKB=P08861 P08861 CELA3B PTHR24257:SF22 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 3B serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=30512|UniProtKB=Q5JSH3 Q5JSH3 WDR44 PTHR14221:SF0 WD REPEAT DOMAIN 44 WD REPEAT-CONTAINING PROTEIN 44 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 HUMAN|HGNC=9173|UniProtKB=P09884 P09884 POLA1 PTHR45861:SF1 DNA POLYMERASE ALPHA CATALYTIC SUBUNIT DNA POLYMERASE ALPHA CATALYTIC SUBUNIT DNA replication origin binding#GO:0003688;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;DNA-directed DNA polymerase activity#GO:0003887;small molecule binding#GO:0036094;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;DNA polymerase activity#GO:0034061 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;cellular nitrogen compound catabolic process#GO:0044270;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;cell cycle DNA replication#GO:0044786;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nuclear DNA replication#GO:0033260;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organelle organization#GO:0006996;DNA biosynthetic process#GO:0071897;mitotic DNA replication#GO:1902969;organic cyclic compound catabolic process#GO:1901361;cell cycle#GO:0007049;organelle fission#GO:0048285;aromatic compound biosynthetic process#GO:0019438;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 pre-replicative complex#GO:0036387;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;epsilon DNA polymerase complex#GO:0008622;replisome#GO:0030894;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;replication fork#GO:0005657;membrane-enclosed lumen#GO:0031974;origin recognition complex#GO:0000808;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;DNA replication preinitiation complex#GO:0031261;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;CMG complex#GO:0071162;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 DNA metabolism protein#PC00009 DNA replication#P00017>Pol alpha#P00531 HUMAN|HGNC=9340|UniProtKB=P10163 P10163 PRB4 PTHR23203:SF15 PROLINE-RICH PROTEIN BASIC SALIVARY PROLINE-RICH PROTEIN 4 antimicrobial response protein#PC00051 HUMAN|HGNC=30581|UniProtKB=Q8TE77 Q8TE77 SSH3 PTHR45864:SF4 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 3 hydrolase activity, acting on ester bonds#GO:0016788;cytoskeletal protein binding#GO:0008092;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;actin binding#GO:0003779;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 HUMAN|HGNC=19829|UniProtKB=Q8N128 Q8N128 FAM177A1 PTHR31206:SF5 LP10445P PROTEIN FAM177A1 HUMAN|HGNC=8690|UniProtKB=Q9Y5E4 Q9Y5E4 PCDHB5 PTHR24028:SF90 CADHERIN-87A PROTOCADHERIN BETA-5 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=951|UniProtKB=P78367 P78367 NKX3-2 PTHR24340:SF34 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-3.2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=34408|UniProtKB=Q68EN5 Q68EN5 KIAA0895L PTHR31817:SF1 FAMILY NOT NAMED KIAA0895 LIKE HUMAN|HGNC=28696|UniProtKB=Q8N184 Q8N184 ZNF567 PTHR24404:SF75 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 567 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11724|UniProtKB=Q02763 Q02763 TEK PTHR24416:SF125 TYROSINE-PROTEIN KINASE RECEPTOR ANGIOPOIETIN-1 RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of localization#GO:0032879;positive regulation of protein modification process#GO:0031401;cell population proliferation#GO:0008283;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;epithelial cell proliferation#GO:0050673;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;endothelial cell migration#GO:0043542;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;inositol lipid-mediated signaling#GO:0048017;protein kinase B signaling#GO:0043491;movement of cell or subcellular component#GO:0006928;positive regulation of protein kinase B signaling#GO:0051897;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of signaling#GO:0023051;endothelial cell proliferation#GO:0001935;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;phosphatidylinositol-mediated signaling#GO:0048015;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;phosphatidylinositol 3-kinase signaling#GO:0014065;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of phosphatidylinositol 3-kinase signaling#GO:0014066;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477;regulation of protein kinase B signaling#GO:0051896;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>Tie2#P00247 HUMAN|HGNC=7539|UniProtKB=Q9NR99 Q9NR99 MXRA5 PTHR45842:SF4 SYNAPTIC ADHESION-LIKE MOLECULE SALM MATRIX-REMODELING-ASSOCIATED PROTEIN 5 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=25257|UniProtKB=Q96B42 Q96B42 TMEM18 PTHR22593:SF2 TRANSMEMBRANE PROTEIN 18 TRANSMEMBRANE PROTEIN 18 HUMAN|HGNC=21411|UniProtKB=Q9BRQ8 Q9BRQ8 AIFM2 PTHR43735:SF3 APOPTOSIS-INDUCING FACTOR 1 FERROPTOSIS SUPPRESSOR PROTEIN 1 nucleotide binding#GO:0000166;electron transfer activity#GO:0009055;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidoreductase#PC00176 p53 pathway#P00059>NOXA#G01572 HUMAN|HGNC=23018|UniProtKB=Q6UE05 Q6UE05 TMEM270 PTHR37369:SF1 TRANSMEMBRANE PROTEIN 270 TRANSMEMBRANE PROTEIN 270 HUMAN|HGNC=17697|UniProtKB=Q9NP81 Q9NP81 SARS2 PTHR11778:SF7 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, CYTOPLASMIC-RELATED catalytic activity, acting on RNA#GO:0140098;tRNA binding#GO:0000049;ligase activity#GO:0016874;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a tRNA#GO:0140101;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=8092|UniProtKB=Q3MII6 Q3MII6 TBC1D25 PTHR22957:SF333 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 25 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=31666|UniProtKB=Q6DHV5 Q6DHV5 CC2D2B PTHR20837:SF2 CENTROSOMAL PROTEIN-RELATED PROTEIN CC2D2B HUMAN|HGNC=21714|UniProtKB=Q9P0W0 Q9P0W0 IFNK PTHR11691:SF6 TYPE I INTERFERON INTERFERON KAPPA receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=10751|UniProtKB=P49908 P49908 SELENOP PTHR10105:SF3 SELENOPROTEIN P SELENOPROTEIN P binding#GO:0005488 cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=33753|UniProtKB=Q2T9L4 Q2T9L4 INSYN1 PTHR15917:SF3 FAMILY NOT NAMED INHIBITORY SYNAPTIC FACTOR 1 HUMAN|HGNC=4606|UniProtKB=P30101 P30101 PDIA3 PTHR18929:SF242 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A3 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;cellular process#GO:0009987;cellular response to stress#GO:0033554;protein folding#GO:0006457 cytoplasm#GO:0005737;cell surface#GO:0009986;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=2370|UniProtKB=O60244 O60244 MED14 PTHR12809:SF2 MEDIATOR COMPLEX SUBUNIT MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=23236|UniProtKB=Q9H3F6 Q9H3F6 KCTD10 PTHR11145:SF14 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 3 transferase activity#GO:0016740;Ras GTPase binding#GO:0017016;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;GTP-Rho binding#GO:0017049;small GTPase binding#GO:0031267;catalytic activity, acting on a protein#GO:0140096;Rho GTPase binding#GO:0017048 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;negative regulation of Ras protein signal transduction#GO:0046580;regulation of intracellular signal transduction#GO:1902531;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;negative regulation of small GTPase mediated signal transduction#GO:0051058;catabolic process#GO:0009056;intracellular signal transduction#GO:0035556;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;primary metabolic process#GO:0044238;regulation of small GTPase mediated signal transduction#GO:0051056;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of Ras protein signal transduction#GO:0046578 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 HUMAN|HGNC=8875|UniProtKB=Q16877 Q16877 PFKFB4 PTHR10606:SF14 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 4 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578 carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 carbohydrate phosphatase#PC00066 HUMAN|HGNC=19286|UniProtKB=Q6P3W7 Q6P3W7 SCYL2 PTHR12984:SF18 SCY1-RELATED S/T PROTEIN KINASE-LIKE SCY1-LIKE PROTEIN 2 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=16095|UniProtKB=Q96NM4 Q96NM4 TOX2 PTHR45781:SF5 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2749|UniProtKB=Q14562 Q14562 DHX8 PTHR18934:SF85 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX8 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein-containing complex disassembly#GO:0032984;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA helicase#PC00032 HUMAN|HGNC=16858|UniProtKB=Q92738 Q92738 USP6NL PTHR22957:SF193 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN USP6 N-TERMINAL-LIKE PROTEIN GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=28322|UniProtKB=Q96C55 Q96C55 ZNF524 PTHR24390:SF109 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 524 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26454|UniProtKB=Q6PF06 Q6PF06 TRMT10B PTHR13563:SF13 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG B RNA methyltransferase#PC00033 HUMAN|HGNC=12453|UniProtKB=Q01081 Q01081 U2AF1 PTHR12620:SF11 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT SPLICING FACTOR U2AF 35 KDA SUBUNIT-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=1591|UniProtKB=P41002 P41002 CCNF PTHR10177:SF496 CYCLINS CYCLIN-F cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 HUMAN|Ensembl=ENSG00000284976|UniProtKB=A0A2R8Y4M4 A0A2R8Y4M4 ENSG00000284976 PTHR22791:SF23 UNCHARACTERIZED RING-TYPE DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=8370|UniProtKB=Q8NGA2 Q8NGA2 OR7A2P PTHR48001:SF155 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7A2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=20155|UniProtKB=Q86U06 Q86U06 RBM23 PTHR48036:SF3 SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED RNA-BINDING PROTEIN 23-RELATED RNA splicing factor#PC00148 HUMAN|HGNC=9121|UniProtKB=P54277 P54277 PMS1 PTHR10073:SF54 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL PMS1 PROTEIN HOMOLOG 1 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=25766|UniProtKB=Q49A88 Q49A88 CCDC14 PTHR22367:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 14 COILED-COIL DOMAIN-CONTAINING PROTEIN 14 HUMAN|HGNC=4632|UniProtKB=P09488 P09488 GSTM1 PTHR11571:SF247 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 1 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=8893|UniProtKB=P49763 P49763 PGF PTHR12025:SF9 VASCULAR ENDOTHELIAL GROWTH FACTOR PLACENTA GROWTH FACTOR receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein metabolic process#GO:0051246;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;positive regulation of protein modification process#GO:0031401;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;tube morphogenesis#GO:0035239;epithelial cell proliferation#GO:0050673;sprouting angiogenesis#GO:0002040;positive regulation of epithelial cell proliferation#GO:0050679;cellular protein metabolic process#GO:0044267;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;angiogenesis#GO:0001525;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;taxis#GO:0042330;signal transduction#GO:0007165;response to hypoxia#GO:0001666;positive regulation of angiogenesis#GO:0045766;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of leukocyte migration#GO:0002687;system development#GO:0048731;regulation of chemotaxis#GO:0050920;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;myeloid leukocyte migration#GO:0097529;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;response to oxygen levels#GO:0070482;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;positive regulation of immune system process#GO:0002684;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cell chemotaxis#GO:0060326;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;positive regulation of cellular component movement#GO:0051272;regulation of phosphorus metabolic process#GO:0051174;leukocyte migration#GO:0050900;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;nitrogen compound metabolic process#GO:0006807;vasculature development#GO:0001944;response to abiotic stimulus#GO:0009628;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;response to decreased oxygen levels#GO:0036293;tube development#GO:0035295;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;positive chemotaxis#GO:0050918;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;developmental process#GO:0032502;endothelial cell proliferation#GO:0001935;regulation of angiogenesis#GO:0045765;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;positive regulation of developmental process#GO:0051094;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of leukocyte chemotaxis#GO:0002690;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=1908|UniProtKB=Q96RL7 Q96RL7 VPS13A PTHR16166:SF22 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13A cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein localization to Golgi apparatus#GO:0034067;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;autophagy#GO:0006914 cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898 membrane traffic protein#PC00150 HUMAN|HGNC=11100|UniProtKB=P51532 P51532 SMARCA4 PTHR10799:SF76 SNF2/RAD54 HELICASE FAMILY TRANSCRIPTION ACTIVATOR BRG1 pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;transcription factor binding#GO:0008134;ATPase activity#GO:0016887 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=6693|UniProtKB=Q9NZR2 Q9NZR2 LRP1B PTHR22722:SF5 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1B Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 HUMAN|HGNC=16468|UniProtKB=P83111 P83111 LACTB PTHR46520:SF1 SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL HUMAN|Ensembl=ENSG00000278082|UniProtKB=A0A0J9YWU9 A0A0J9YWU9 ENSG00000278082 PTHR23266:SF323 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=24669|UniProtKB=Q6QHK4 Q6QHK4 FIGLA PTHR23349:SF57 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FACTOR IN THE GERMLINE ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=20992|UniProtKB=O75818 O75818 RPP40 PTHR15396:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P40 RIBONUCLEASE P PROTEIN SUBUNIT P40 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;ribonuclease activity#GO:0004540;catalytic activity, acting on a tRNA#GO:0140101 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;cleavage involved in rRNA processing#GO:0000469;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;endonucleolytic cleavage involved in rRNA processing#GO:0000478;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 small nucleolar ribonucleoprotein complex#GO:0005732;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172;ribonuclease P complex#GO:0030677;intracellular#GO:0005622;catalytic complex#GO:1902494 HUMAN|HGNC=13280|UniProtKB=Q96HE7 Q96HE7 ERO1A PTHR12613:SF1 ERO1-RELATED ERO1-LIKE PROTEIN ALPHA isomerase activity#GO:0016853;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 oxidoreductase#PC00176 HUMAN|HGNC=14932|UniProtKB=Q9Y6E7 Q9Y6E7 SIRT4 PTHR48252:SF11 HISTONE DEACETYLASE 2-RELATED NAD-DEPENDENT PROTEIN LIPOAMIDASE SIRTUIN-4, MITOCHONDRIAL HUMAN|HGNC=27028|UniProtKB=A4QMS7 A4QMS7 C5orf49 PTHR34444:SF1 LOC361192 LOC361192 HUMAN|HGNC=2731|UniProtKB=Q16832 Q16832 DDR2 PTHR24416:SF295 TYROSINE-PROTEIN KINASE RECEPTOR DISCOIDIN DOMAIN-CONTAINING RECEPTOR 2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;collagen binding#GO:0005518;molecular transducer activity#GO:0060089;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=26523|UniProtKB=Q5W0A0 Q5W0A0 ERICH6B PTHR23093:SF17 SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 GLUTAMATE-RICH PROTEIN 6B HUMAN|HGNC=25097|UniProtKB=Q8TDN4 Q8TDN4 CABLES1 PTHR22896:SF1 CDK5 AND ABL1 ENZYME SUBSTRATE 1 CDK5 AND ABL1 ENZYME SUBSTRATE 1 HUMAN|HGNC=29845|UniProtKB=Q6PP77 Q6PP77 XKRX PTHR14297:SF4 MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER XK-RELATED PROTEIN 2 HUMAN|HGNC=28902|UniProtKB=Q8IUH8 Q8IUH8 SPPL2C PTHR12174:SF38 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2C hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;lysosome#GO:0005764;intracellular#GO:0005622;cytoplasmic side of membrane#GO:0098562;leaflet of membrane bilayer#GO:0097478;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell periphery#GO:0071944;membrane#GO:0016020;lytic vacuole#GO:0000323;side of membrane#GO:0098552;whole membrane#GO:0098805;intrinsic component of endoplasmic reticulum membrane#GO:0031227;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;Golgi-associated vesicle membrane#GO:0030660;endomembrane system#GO:0012505;integral component of endoplasmic reticulum membrane#GO:0030176;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 aspartic protease#PC00053 HUMAN|HGNC=29919|UniProtKB=Q86Y26 Q86Y26 NUTM1 PTHR22879:SF13 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 1 HUMAN|HGNC=7061|UniProtKB=P10620 P10620 MGST1 PTHR10689:SF3 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 oxidation-reduction process#GO:0055114;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transferase#PC00220 HUMAN|HGNC=24723|UniProtKB=Q9H6R3 Q9H6R3 ACSS3 PTHR43347:SF3 ACYL-COA SYNTHETASE ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL ligase#PC00142 Methylcitrate cycle#P02754>Acetyl-CoA synthetase#P03030;Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 HUMAN|HGNC=14935|UniProtKB=Q9NRC8 Q9NRC8 SIRT7 PTHR48252:SF51 HISTONE DEACETYLASE 2-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-7 HUMAN|HGNC=25933|UniProtKB=Q6ZW33 Q6ZW33 MICALCL PTHR23167:SF68 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED MICAL C-TERMINAL-LIKE PROTEIN HUMAN|HGNC=9799|UniProtKB=Q9UBK7 Q9UBK7 RABL2A PTHR24073:SF263 DRAB5-RELATED RAB-LIKE PROTEIN 2A-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=19318|UniProtKB=Q8IVL6 Q8IVL6 P3H3 PTHR14049:SF14 LEPRECAN 1 PROLYL 3-HYDROXYLASE 3 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=10596|UniProtKB=Q9UQD0 Q9UQD0 SCN8A PTHR10037:SF23 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 8 SUBUNIT ALPHA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sodium channel activity#GO:0005272;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;sodium ion transport#GO:0006814;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=9639|UniProtKB=B0YJ81 B0YJ81 HACD1 PTHR11035:SF22 PTPLA DOMAIN PROTEIN VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 1 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=19026|UniProtKB=Q8NFW5 Q8NFW5 DMBX1 PTHR46639:SF2 DIENCEPHALON/MESENCEPHALON HOMEOBOX PROTEIN 1 DIENCEPHALON/MESENCEPHALON HOMEOBOX PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 homeodomain transcription factor#PC00119 HUMAN|HGNC=23397|UniProtKB=Q5T1M5 Q5T1M5 FKBP15 PTHR44927:SF1 FK506-BINDING PROTEIN 15 FK506-BINDING PROTEIN 15 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 HUMAN|HGNC=21489|UniProtKB=Q9NTX5 Q9NTX5 ECHDC1 PTHR11941:SF27 ENOYL-COA HYDRATASE-RELATED ETHYLMALONYL-COA DECARBOXYLASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydratase#PC00120 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 HUMAN|HGNC=10850|UniProtKB=P34896 P34896 SHMT1 PTHR11680:SF28 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC amino acid binding#GO:0016597;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 cellular aromatic compound metabolic process#GO:0006725;pteridine-containing compound metabolic process#GO:0042558;organonitrogen compound catabolic process#GO:1901565;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058;carboxylic acid biosynthetic process#GO:0046394;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular amino acid catabolic process#GO:0009063;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 methyltransferase#PC00155 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 HUMAN|HGNC=14287|UniProtKB=Q8N0W4 Q8N0W4 NLGN4X PTHR43903:SF10 NEUROLIGIN NEUROLIGIN-4, X-LINKED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;transport#GO:0006810;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;vesicle organization#GO:0016050;cell junction assembly#GO:0034329;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;endocytosis#GO:0006897;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;vesicle budding from membrane#GO:0006900;synapse assembly#GO:0007416;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;vesicle-mediated transport in synapse#GO:0099003 cell surface#GO:0009986;synapse#GO:0045202;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;cell junction#GO:0030054;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=6478|UniProtKB=Q6ISS4 Q6ISS4 LAIR2 PTHR11738:SF129 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR 2 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=24327|UniProtKB=A8MV65 A8MV65 VGLL3 PTHR15950:SF16 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 3 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=1815|UniProtKB=P40198 P40198 CEACAM3 PTHR44427:SF1 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1-RELATED HUMAN|HGNC=18821|UniProtKB=Q6XZB0 Q6XZB0 LIPI PTHR11610:SF103 LIPASE LIPASE MEMBER I hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid catabolic process#GO:0044242;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;triglyceride metabolic process#GO:0006641;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerolipid catabolic process#GO:0046503;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143 HUMAN|HGNC=6548|UniProtKB=O95751 O95751 LDOC1 PTHR15503:SF27 LDOC1 RELATED PROTEIN LDOC1 HUMAN|HGNC=16666|UniProtKB=Q9HAQ2 Q9HAQ2 KIF9 PTHR24115:SF191 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF9 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=37142|UniProtKB=E7ETH6 E7ETH6 ZNF587B PTHR24381:SF389 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 587B DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1325|UniProtKB=P04003 P04003 C4BPA PTHR19325:SF541 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING C4B-BINDING PROTEIN ALPHA CHAIN HUMAN|HGNC=16272|UniProtKB=Q96JK9 Q96JK9 MAML3 PTHR15692:SF8 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 3 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 HUMAN|HGNC=9307|UniProtKB=Q06190 Q06190 PPP2R3A PTHR14095:SF3 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT ALPHA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 protein phosphatase#PC00195 HUMAN|HGNC=26537|UniProtKB=Q8N443 Q8N443 RIBC1 PTHR14517:SF11 RIB43A-RELATED RIB43A-LIKE WITH COILED-COILS PROTEIN 1 cytoskeletal protein#PC00085 HUMAN|HGNC=7597|UniProtKB=O00159 O00159 MYO1C PTHR13140:SF255 MYOSIN UNCONVENTIONAL MYOSIN-IC pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 microvillus#GO:0005902;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=12784|UniProtKB=P41221 P41221 WNT5A PTHR12027:SF33 WNT RELATED PROTEIN WNT-5A receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=18138|UniProtKB=Q9Y262 Q9Y262 EIF3L PTHR13242:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=16702|UniProtKB=Q9BT78 Q9BT78 COPS4 PTHR10855:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 COP9 SIGNALOSOME COMPLEX SUBUNIT 4 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein-specific protease activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 HUMAN|HGNC=24173|UniProtKB=Q9H3M9 Q9H3M9 ATXN3L PTHR14159:SF0 ATAXIN-3-RELATED ATAXIN-3-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;hydrolase activity#GO:0016787;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=437|UniProtKB=P09923 P09923 ALPI PTHR11596:SF87 ALKALINE PHOSPHATASE INTESTINAL-TYPE ALKALINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=29517|UniProtKB=Q96C10 Q96C10 DHX58 PTHR14074:SF7 HELICASE WITH DEATH DOMAIN-RELATED ATP-DEPENDENT RNA HELICASE DHX58-RELATED cation binding#GO:0043169;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;zinc ion binding#GO:0008270;binding#GO:0005488;organic cyclic compound binding#GO:0097159;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;double-stranded RNA binding#GO:0003725 response to virus#GO:0009615;positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;positive regulation of metabolic process#GO:0009893;innate immune response#GO:0045087;positive regulation of cytokine production#GO:0001819;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;positive regulation of macromolecule metabolic process#GO:0010604;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=16100|UniProtKB=Q5JX71 Q5JX71 FAM209A PTHR35157:SF1 PROTEIN FAM209A PROTEIN FAM209A HUMAN|HGNC=15456|UniProtKB=Q14703 Q14703 MBTPS1 PTHR43806:SF7 PEPTIDASE S8 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-1 PROTEASE serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 HUMAN|HGNC=25886|UniProtKB=Q6NZ67 Q6NZ67 MZT2B PTHR28578:SF4 MITOTIC-SPINDLE ORGANIZING PROTEIN 2A-RELATED MITOTIC-SPINDLE ORGANIZING PROTEIN 2B intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;microtubule organizing center#GO:0005815;intracellular#GO:0005622;gamma-tubulin complex#GO:0000930;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=19717|UniProtKB=Q8NEA9 Q8NEA9 GMCL2 PTHR23231:SF18 GERM CELL-LESS PROTEIN GERM CELL-LESS PROTEIN-LIKE 2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=3416|UniProtKB=P19235 P19235 EPOR PTHR23037:SF28 CYTOKINE RECEPTOR ERYTHROPOIETIN RECEPTOR transmembrane signal receptor#PC00197 HUMAN|HGNC=27900|UniProtKB=Q0P5P2 Q0P5P2 C17orf67 PTHR35971:SF1 SI:DKEY-31G6.6 SI:DKEY-31G6.6 HUMAN|HGNC=30882|UniProtKB=Q9NZ43 Q9NZ43 USE1 PTHR13050:SF7 USE1-LIKE PROTEIN VESICLE TRANSPORT PROTEIN USE1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=13999|UniProtKB=P57071 P57071 PRDM15 PTHR24393:SF107 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 15 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;hematopoietic or lymphoid organ development#GO:0048534;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of hemopoiesis#GO:1903706;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15990|UniProtKB=P28676 P28676 GCA PTHR46735:SF5 CALPAIN, SMALL SUBUNIT 1 A-RELATED GRANCALCIN HUMAN|HGNC=2499|UniProtKB=Q16619 Q16619 CTF1 PTHR21353:SF2 FAMILY NOT NAMED CARDIOTROPHIN-1 HUMAN|HGNC=1237|UniProtKB=Q9NRR5 Q9NRR5 UBQLN4 PTHR10677:SF21 UBIQUILIN UBIQUILIN-4 protein binding#GO:0005515;binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165 HUMAN|HGNC=26033|UniProtKB=Q96PZ0 Q96PZ0 PUS7 PTHR13326:SF29 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE 7 HOMOLOG isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=16701|UniProtKB=P19105 P19105 MYL12A PTHR23049:SF57 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 12A actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=19909|UniProtKB=Q8N5L8 Q8N5L8 RPP25L PTHR13516:SF8 RIBONUCLEASE P SUBUNIT P25 RIBONUCLEASE P PROTEIN SUBUNIT P25-LIKE PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 small nucleolar ribonucleoprotein complex#GO:0005732;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;ribonuclease MRP complex#GO:0000172;intracellular#GO:0005622;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 endoribonuclease#PC00094 HUMAN|HGNC=7794|UniProtKB=P19838 P19838 NFKB1 PTHR24169:SF9 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;B cell activation#P00010>NFkappaB#P00370;T cell activation#P00053>NFkappaB#P01298;Toll receptor signaling pathway#P00054>NFkappaB#P01354;Apoptosis signaling pathway#P00006>NFkappaB#P00297 HUMAN|HGNC=12971|UniProtKB=Q2M3W8 Q2M3W8 ZNF181 PTHR24377:SF395 IP01015P-RELATED ZINC FINGER PROTEIN 181-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16187|UniProtKB=Q9NQ40 Q9NQ40 SLC52A3 PTHR12929:SF4 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 3 anion transmembrane transporter activity#GO:0008509;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=17702|UniProtKB=Q9H9S3 Q9H9S3 SEC61A2 PTHR10906:SF10 SECY/SEC61-ALPHA FAMILY MEMBER PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 2 signal sequence binding#GO:0005048;transmembrane transporter activity#GO:0022857;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;amide transmembrane transporter activity#GO:0042887;protein transmembrane transporter activity#GO:0008320;protein-containing complex binding#GO:0044877;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;translation#GO:0006412;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;posttranslational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein localization to organelle#GO:0033365;cellular protein metabolic process#GO:0044267;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;amide biosynthetic process#GO:0043604;protein targeting to membrane#GO:0006612;peptide biosynthetic process#GO:0043043;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=288|UniProtKB=P13945 P13945 ADRB3 PTHR24248:SF3 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-3 ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;organic cyclic compound binding#GO:0097159;transmembrane signaling receptor activity#GO:0004888 blood circulation#GO:0008015;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of blood vessel diameter#GO:0097746;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of blood pressure#GO:0045776;activation of adenylate cyclase activity#GO:0007190;regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of systemic arterial blood pressure#GO:0003073;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of blood pressure#GO:0008217;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Beta3 adrenergic receptor signaling pathway#P04379>Beta3#P04449;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=7555|UniProtKB=P12524 P12524 MYCL PTHR45851:SF5 MYC PROTO-ONCOGENE PROTEIN L-MYC-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 HUMAN|HGNC=28030|UniProtKB=Q6PKC3 Q6PKC3 TXNDC11 PTHR46497:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 oxidoreductase#PC00176 HUMAN|HGNC=27273|UniProtKB=Q6PEW1 Q6PEW1 ZCCHC12 PTHR23095:SF18 PARANEOPLASTIC ANTIGEN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 12 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=1355|UniProtKB=Q9Y236 Q9Y236 OSGIN2 PTHR15192:SF4 PROTEIN CBG05349 OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 2 HUMAN|HGNC=16995|UniProtKB=Q969M2 Q969M2 GJA10 PTHR11984:SF9 CONNEXIN GAP JUNCTION ALPHA-10 PROTEIN gap junction#PC00105 HUMAN|HGNC=19098|UniProtKB=Q6ZRY4 Q6ZRY4 RBPMS2 PTHR10501:SF30 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B RNA-BINDING PROTEIN WITH MULTIPLE SPLICING 2 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 muscle structure development#GO:0061061;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;negative regulation of biological process#GO:0048519;muscle cell differentiation#GO:0042692;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523 RNA splicing factor#PC00148 HUMAN|HGNC=1055|UniProtKB=P62952 P62952 BLCAP PTHR13259:SF1 BLADDER CANCER 10 KD PROTEIN HOMOLOG BLADDER CANCER-ASSOCIATED PROTEIN HUMAN|HGNC=18597|UniProtKB=P59817 P59817 ZNF280A PTHR24388:SF47 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 280A cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11653|UniProtKB=P20062 P20062 TCN2 PTHR10559:SF14 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR TRANSCOBALAMIN-2 tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;transport#GO:0006810 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=14685|UniProtKB=Q9Y624 Q9Y624 F11R PTHR45113:SF1 JUNCTIONAL ADHESION MOLECULE A JUNCTIONAL ADHESION MOLECULE A cellular developmental process#GO:0048869;epithelium development#GO:0060429;transport#GO:0006810;system process#GO:0003008;developmental process#GO:0032502;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;localization#GO:0051179;cell differentiation#GO:0030154;digestion#GO:0007586;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446;regulation of membrane permeability#GO:0090559 cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;apical junction complex#GO:0043296 HUMAN|HGNC=7372|UniProtKB=P08118 P08118 MSMB PTHR10500:SF8 BETA-MICROSEMINOPROTEIN BETA-MICROSEMINOPROTEIN intercellular signal molecule#PC00207 HUMAN|HGNC=3793|UniProtKB=P14207 P14207 FOLR2 PTHR10517:SF8 FOLATE RECEPTOR FOLATE RECEPTOR BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell recognition#GO:0008037;plasma membrane fusion#GO:0045026;fertilization#GO:0009566;membrane organization#GO:0061024;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;biological adhesion#GO:0022610;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;multi-organism process#GO:0051704;cell-cell recognition#GO:0009988;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;membrane fusion#GO:0061025;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;multi-organism reproductive process#GO:0044703 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;anchored component of plasma membrane#GO:0046658;intrinsic component of membrane#GO:0031224;intrinsic component of plasma membrane#GO:0031226;anchored component of membrane#GO:0031225;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=14951|UniProtKB=Q5SWA1 Q5SWA1 PPP1R15B PTHR16489:SF11 GH11727P PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;positive regulation of protein modification process#GO:0031401;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;regulation of phosphoprotein phosphatase activity#GO:0043666;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;regulation of phosphatase activity#GO:0010921;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=30863|UniProtKB=Q9UDW1 Q9UDW1 UQCR10 PTHR12980:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX, SUBUNIT X CYTOCHROME B-C1 COMPLEX SUBUNIT 9 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular component biogenesis#GO:0044085;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cytochrome complex assembly#GO:0017004;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;protein-containing complex subunit organization#GO:0043933;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex III assembly#GO:0034551;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;mitochondrial respiratory chain complex assembly#GO:0033108;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;metabolic process#GO:0008152;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;organelle organization#GO:0006996;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respiratory chain complex III#GO:0005750;membrane-bounded organelle#GO:0043227 reductase#PC00198 HUMAN|HGNC=545|UniProtKB=P20073 P20073 ANXA7 PTHR10502:SF102 ANNEXIN ANNEXIN A7 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calcium-binding protein#PC00060 HUMAN|HGNC=186|UniProtKB=P00813 P00813 ADA PTHR11409:SF43 ADENOSINE DEAMINASE ADENOSINE DEAMINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine-containing compound metabolic process#GO:0072521;pigment biosynthetic process#GO:0046148;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase biosynthetic process#GO:0009113;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 deaminase#PC00088 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 HUMAN|HGNC=31914|UniProtKB=Q8IUI4 Q8IUI4 SNX29P2 PTHR47194:SF2 SORTING NEXIN-29-RELATED SORTING NEXIN-29-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=14871|UniProtKB=Q96A00 Q96A00 PPP1R14A PTHR16188:SF4 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14A phosphatase binding#GO:0019902;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096;protein phosphatase inhibitor activity#GO:0004864 phosphatase modulator#PC00184 HUMAN|HGNC=29504|UniProtKB=Q401N2 Q401N2 ZACN PTHR18945:SF786 NEUROTRANSMITTER GATED ION CHANNEL ZINC-ACTIVATED LIGAND-GATED ION CHANNEL signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=2235|UniProtKB=Q99612 Q99612 KLF6 PTHR23235:SF50 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28437|UniProtKB=Q6P087 Q6P087 RPUSD3 PTHR21600:SF49 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE MITOCHONDRIAL MRNA PSEUDOURIDINE SYNTHASE RPUSD3 RNA processing factor#PC00147 HUMAN|HGNC=9315|UniProtKB=P16298 P16298 PPP3CB PTHR45673:SF7 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT BETA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 protein phosphatase#PC00195 T cell activation#P00053>Calcineurin#P01315;Wnt signaling pathway#P00057>Calcineurin#P01446;B cell activation#P00010>Calcineurin#P00386 HUMAN|HGNC=15329|UniProtKB=Q8NGE5 Q8NGE5 OR10A7 PTHR26453:SF22 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A7 transmembrane signal receptor#PC00197 HUMAN|HGNC=9093|UniProtKB=P55058 P55058 PLTP PTHR10504:SF16 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED PHOSPHOLIPID TRANSFER PROTEIN cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;amide transport#GO:0042886;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;lipid localization#GO:0010876;protein-containing complex subunit organization#GO:0043933 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=26591|UniProtKB=Q5FWE3 Q5FWE3 PRRT3 PTHR47400:SF1 PROLINE-RICH TRANSMEMBRANE PROTEIN 3 PROLINE-RICH TRANSMEMBRANE PROTEIN 3 HUMAN|HGNC=26345|UniProtKB=Q96LL4 Q96LL4 C8orf48 PTHR35256:SF1 CHROMOSOME 8 OPEN READING FRAME 48 CHROMOSOME 8 OPEN READING FRAME 48 HUMAN|HGNC=7785|UniProtKB=O00712 O00712 NFIB PTHR11492:SF4 NUCLEAR FACTOR I NUCLEAR FACTOR 1 B-TYPE cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|Ensembl=ENSG00000225805|UniProtKB=A0A096LNP1 A0A096LNP1 DEFB131B PTHR47900:SF2 BETA-DEFENSIN 131A BETA-DEFENSIN 131B extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=12788|UniProtKB=Q9H1J5 Q9H1J5 WNT8A PTHR12027:SF92 WNT RELATED PROTEIN WNT-8A receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=1002|UniProtKB=Q8N143 Q8N143 BCL6B PTHR24399:SF37 ZINC FINGER AND BTB DOMAIN-CONTAINING B-CELL CLL/LYMPHOMA 6 MEMBER B PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11904|UniProtKB=O00220 O00220 TNFRSF10A PTHR46330:SF11 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10A positive regulation of apoptotic process#GO:0043065;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TRAIL-R#P00276;p53 pathway#P00059>KILLER/DR5#G01568 HUMAN|HGNC=23032|UniProtKB=Q96HR3 Q96HR3 MED30 PTHR31705:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=16871|UniProtKB=Q5BIV9 Q5BIV9 SPRN PTHR28552:SF1 SHADOW OF PRION PROTEIN SHADOW OF PRION PROTEIN HUMAN|HGNC=6876|UniProtKB=Q16539 Q16539 MAPK14 PTHR24055:SF110 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 14 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>p38#P01352;p38 MAPK pathway#P05918>p38alpha#P06031;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>p38#P00562;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Parkinson disease#P00049>p38 MAPK#P01212;Oxidative stress response#P00046>p38#P01135;FGF signaling pathway#P00021>p38#P00644;CCKR signaling map#P06959>p38MAPK#P07079;CCKR signaling map#P06959>MAPKAP-K2#P07217;VEGF signaling pathway#P00056>p38MAPK#P01423;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;JAK/STAT signaling pathway#P00038>Serine kinase#P01029;TGF-beta signaling pathway#P00052>P38#P01275;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Angiogenesis#P00005>p38MAPK#P00182;Ras Pathway#P04393>p38#P04558;B cell activation#P00010>p38#P00384 HUMAN|HGNC=29805|UniProtKB=Q9BYH8 Q9BYH8 NFKBIZ PTHR24124:SF5 ANKYRIN REPEAT FAMILY A NF-KAPPA-B INHIBITOR ZETA regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=2016|UniProtKB=Q9UQC9 Q9UQC9 CLCA2 PTHR10579:SF66 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=1143|UniProtKB=Q6UXE8 Q6UXE8 BTNL3 PTHR24100:SF135 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=8142|UniProtKB=Q9H6K4 Q9H6K4 OPA3 PTHR12499:SF0 OPTIC ATROPHY 3 PROTEIN OPA3 OPTIC ATROPHY 3 PROTEIN regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;lipid metabolic process#GO:0006629;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;regulation of metabolic process#GO:0019222;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5100|UniProtKB=P31260 P31260 HOXA10 PTHR45874:SF1 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-A10 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=20565|UniProtKB=Q86TB3 Q86TB3 ALPK2 PTHR47091:SF2 ALPHA-PROTEIN KINASE 2-RELATED ALPHA-PROTEIN KINASE 2 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=21162|UniProtKB=Q495X7 Q495X7 TRIM60 PTHR24103:SF304 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 60 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=30778|UniProtKB=Q8WXI9 Q8WXI9 GATAD2B PTHR13455:SF4 TRANSCRIPTIONAL REPRESSOR P66-RELATED TRANSCRIPTIONAL REPRESSOR P66-BETA sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=3454|UniProtKB=Q14264 Q14264 ERV3-1 PTHR10424:SF68 VIRAL ENVELOPE PROTEIN ENDOGENOUS RETROVIRUS GROUP 3 MEMBER 1 ENV POLYPROTEIN viral or transposable element protein#PC00237 HUMAN|HGNC=864|UniProtKB=O75348 O75348 ATP6V1G1 PTHR12713:SF12 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G 1 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002 HUMAN|HGNC=19963|UniProtKB=Q6EMB2 Q6EMB2 TTLL5 PTHR12241:SF16 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL5 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=7871|UniProtKB=Q15233 Q15233 NONO PTHR23189:SF15 RNA RECOGNITION MOTIF-CONTAINING NON-POU DOMAIN-CONTAINING OCTAMER-BINDING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;RNA splicing, via transesterification reactions#GO:0000375;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=34418|UniProtKB=Q86W67 Q86W67 FAM228A PTHR28584:SF2 FAMILY WITH SEQUENCE SIMILARITY 228 MEMBER A PROTEIN FAM228A HUMAN|HGNC=14047|UniProtKB=Q9Y2R5 Q9Y2R5 MRPS17 PTHR24088:SF2 28S RIBOSOMAL PROTEIN S17, MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S17, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 HUMAN|HGNC=17344|UniProtKB=O60287 O60287 URB1 PTHR13500:SF0 NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1 NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12495|UniProtKB=Q15819 Q15819 UBE2V2 PTHR24068:SF177 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;protein K63-linked ubiquitination#GO:0070534;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=2032|UniProtKB=O95832 O95832 CLDN1 PTHR12002:SF92 CLAUDIN CLAUDIN-1 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=30559|UniProtKB=Q7L4I2 Q7L4I2 RSRC2 PTHR22426:SF2 UNCHARACTERIZED ARGININE/SERINE-RICH COILED-COIL PROTEIN 2 HUMAN|HGNC=34447|UniProtKB=P47929 P47929 LGALS7B PTHR11346:SF107 GALECTIN GALECTIN-7 extracellular matrix protein#PC00102 HUMAN|HGNC=9448|UniProtKB=P04554 P04554 PRM2 PTHR21341:SF2 PROTAMINE-2 PROTAMINE-2 germ cell development#GO:0007281;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;nucleus organization#GO:0006997;cellular component organization#GO:0016043;spermatid differentiation#GO:0048515;cellular process#GO:0009987;multi-organism process#GO:0051704;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;organelle organization#GO:0006996;anatomical structure development#GO:0048856;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=21216|UniProtKB=Q6BDS2 Q6BDS2 UHRF1BP1 PTHR22774:SF15 UNCHARACTERIZED UHRF1-BINDING PROTEIN 1 HUMAN|HGNC=10530|UniProtKB=O00422 O00422 SAP18 PTHR13082:SF1 SAP18 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=29378|UniProtKB=Q96FC7 Q96FC7 PHYHIPL PTHR15698:SF8 PROTEIN CBG15099 PHYTANOYL-COA HYDROXYLASE-INTERACTING PROTEIN-LIKE HUMAN|HGNC=24246|UniProtKB=Q8N9B8 Q8N9B8 RASGEF1A PTHR23113:SF172 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1A guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=24839|UniProtKB=Q9BWT6 Q9BWT6 MND1 PTHR31398:SF0 MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;M phase#GO:0000279;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;meiosis I cell cycle phase#GO:0098764;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;cell cycle#GO:0007049;organelle fission#GO:0048285;biological phase#GO:0044848;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=33808|UniProtKB=Q6ZVW7 Q6ZVW7 IL17REL PTHR15583:SF10 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR E-LIKE-RELATED signaling receptor activity#GO:0038023;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;cytokine binding#GO:0019955 transmembrane signal receptor#PC00197 HUMAN|HGNC=4090|UniProtKB=P24046 P24046 GABRR1 PTHR18945:SF30 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-1 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;system process#GO:0003008;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=9387|UniProtKB=Q9UGI9 Q9UGI9 PRKAG3 PTHR13780:SF31 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;cation binding#GO:0043169;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;response to nutrient levels#GO:0031667;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 HUMAN|HGNC=712|UniProtKB=P32121 P32121 ARRB2 PTHR11792:SF20 ARRESTIN BETA-ARRESTIN-2 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;negative regulation of signaling#GO:0023057;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;receptor internalization#GO:0031623;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;transport#GO:0006810;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of G protein-coupled receptor signaling pathway#GO:0008277;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;vesicle organization#GO:0016050;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;receptor-mediated endocytosis#GO:0006898;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;ERK1 and ERK2 cascade#GO:0070371;negative regulation of response to stimulus#GO:0048585;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;vesicle budding from membrane#GO:0006900;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>beta-ARR2#P05923;CCKR signaling map#P06959>Beta-arrestin-1/2#P07187;Wnt signaling pathway#P00057>beta-arrestin#P01456;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723 HUMAN|HGNC=37237|UniProtKB=A6NDY0 A6NDY0 PABPN1L PTHR23236:SF27 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EMBRYONIC POLYADENYLATE-BINDING PROTEIN 2 translation initiation factor#PC00224 HUMAN|HGNC=9565|UniProtKB=P51665 P51665 PSMD7 PTHR10540:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 translation initiation factor#PC00224 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 HUMAN|HGNC=4328|UniProtKB=O75311 O75311 GLRA3 PTHR18945:SF455 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-3 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;transport#GO:0006810;system process#GO:0003008;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;regulation of biological process#GO:0050789;inorganic anion transmembrane transport#GO:0098661;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;signaling#GO:0023052;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=8985|UniProtKB=P20848 P20848 SERPINA2 PTHR11461:SF289 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-1-ANTITRYPSIN-RELATED PROTEIN-RELATED serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=14562|UniProtKB=O15155 O15155 BET1 PTHR12791:SF53 GOLGI SNARE BET1-RELATED BET1 HOMOLOG molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular localization#GO:0051641;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 membrane protein complex#GO:0098796;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;SNARE complex#GO:0031201;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 SNARE protein#PC00034 HUMAN|HGNC=25516|UniProtKB=Q8TER5 Q8TER5 ARHGEF40 PTHR45845:SF5 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 40 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=24530|UniProtKB=Q96B77 Q96B77 TMEM186 PTHR13603:SF1 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 186 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=8374|UniProtKB=O60412 O60412 OR7C2 PTHR48001:SF79 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7C2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=28726|UniProtKB=Q5U649 Q5U649 C12orf60 PTHR36289:SF1 CHROMOSOME 12 OPEN READING FRAME 60 CHROMOSOME 6 C12ORF60 HOMOLOG HUMAN|HGNC=15475|UniProtKB=Q9BQR3 Q9BQR3 PRSS27 PTHR24253:SF119 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 27 serine protease#PC00203 HUMAN|HGNC=4499|UniProtKB=O14843 O14843 FFAR3 PTHR45822:SF6 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 3-RELATED HUMAN|HGNC=7106|UniProtKB=P54252 P54252 ATXN3 PTHR14159:SF0 ATAXIN-3-RELATED ATAXIN-3-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;hydrolase activity#GO:0016787;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=34294|UniProtKB=A6NGD5 A6NGD5 ZSCAN5C PTHR23226:SF151 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 5C cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=30273|UniProtKB=Q92930 Q92930 RAB8B PTHR47980:SF6 LD44762P RAS-RELATED PROTEIN RAB-8B cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;protein secretion#GO:0009306;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;response to organonitrogen compound#GO:0010243;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;vesicle fusion#GO:0006906;macromolecule localization#GO:0033036;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;cellular protein localization#GO:0034613;transport#GO:0006810;peptide secretion#GO:0002790;cellular response to nitrogen compound#GO:1901699;amide transport#GO:0042886;organic substance transport#GO:0071702;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;regulation of transport#GO:0051049;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;vesicle organization#GO:0016050;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;response to organic substance#GO:0010033;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;protein localization to membrane#GO:0072657;cellular response to peptide#GO:1901653;Golgi vesicle transport#GO:0048193;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;localization#GO:0051179;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;response to hormone#GO:0009725;membrane fusion#GO:0061025;response to chemical#GO:0042221;organelle organization#GO:0006996;biological regulation#GO:0065007 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;trans-Golgi network transport vesicle#GO:0030140;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=29431|UniProtKB=Q9H792 Q9H792 PEAK1 PTHR22972:SF5 SERINE/THREONINE PROTEIN KINASE INACTIVE TYROSINE-PROTEIN KINASE PEAK1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=16684|UniProtKB=Q96EL3 Q96EL3 MRPL53 PTHR33618:SF1 39S RIBOSOMAL PROTEIN L53, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L53, MITOCHONDRIAL ribosomal protein#PC00202 HUMAN|HGNC=13528|UniProtKB=Q9Y2A9 Q9Y2A9 B3GNT3 PTHR11214:SF23 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 3 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;cellular polysaccharide biosynthetic process#GO:0033692;cellular polysaccharide metabolic process#GO:0044264;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=12736|UniProtKB=O43516 O43516 WIPF1 PTHR23202:SF32 WASP INTERACTING PROTEIN-RELATED WAS/WASL-INTERACTING PROTEIN FAMILY MEMBER 1 movement of cell or subcellular component#GO:0006928;actin filament-based process#GO:0030029;cellular process#GO:0009987 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=2434|UniProtKB=P04141 P04141 CSF2 PTHR10059:SF0 GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR GM-CSF GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 myeloid cell differentiation#GO:0030099;cell differentiation#GO:0030154;immune system process#GO:0002376;cellular developmental process#GO:0048869;system development#GO:0048731;immune system development#GO:0002520;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;hemopoiesis#GO:0030097;hematopoietic or lymphoid organ development#GO:0048534;multicellular organismal process#GO:0032501;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=24565|UniProtKB=Q7Z3B3 Q7Z3B3 KANSL1 PTHR22443:SF14 NON-SPECIFIC LETHAL 1, ISOFORM M KAT8 REGULATORY NSL COMPLEX SUBUNIT 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;protein binding#GO:0005515;H4 histone acetyltransferase activity#GO:0010485;N-acyltransferase activity#GO:0016410 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=27005|UniProtKB=Q5VT99 Q5VT99 LRRC38 PTHR46473:SF4 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 38 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;molecular function regulator#GO:0098772;protein binding#GO:0005515;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 HUMAN|HGNC=28384|UniProtKB=Q5JPI3 Q5JPI3 C3orf38 PTHR21084:SF1 UNCHARACTERIZED SI:CH211-261P9.4 HUMAN|HGNC=4408|UniProtKB=P63218 P63218 GNG5 PTHR13809:SF5 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-5 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 HUMAN|HGNC=2327|UniProtKB=O95639 O95639 CPSF4 PTHR23102:SF18 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 RNA splicing factor#PC00148 HUMAN|HGNC=30551|UniProtKB=P83876 P83876 TXNL4A PTHR12052:SF5 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4A U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 oxidoreductase#PC00176 HUMAN|HGNC=14004|UniProtKB=Q9BYT9 Q9BYT9 ANO3 PTHR12308:SF16 NGEP-RELATED ANOCTAMIN-3 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;inorganic anion transport#GO:0015698;anion transmembrane transport#GO:0098656 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=12538|UniProtKB=P19224 P19224 UGT1A6 PTHR48050:SF7 STEROL 3-BETA-GLUCOSYLTRANSFERASE UDP-GLUCURONOSYLTRANSFERASE 1-6 glycosyltransferase#PC00111 HUMAN|HGNC=13406|UniProtKB=Q9Y6V0 Q9Y6V0 PCLO PTHR14113:SF6 PICCOLO/BASSOON PROTEIN PICCOLO structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;protein localization to synapse#GO:0035418;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;axon#GO:0030424;presynaptic active zone#GO:0048786;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=29092|UniProtKB=O75147 O75147 OBSL1 PTHR13817:SF30 TITIN OBSCURIN-LIKE PROTEIN 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;animal organ development#GO:0048513;developmental process#GO:0032502;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;system development#GO:0048731;synapse assembly#GO:0007416;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;retina development in camera-type eye#GO:0060041;cell junction organization#GO:0034330;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;cell junction assembly#GO:0034329;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 HUMAN|HGNC=31814|UniProtKB=Q6UY18 Q6UY18 LINGO4 PTHR24373:SF156 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 4 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=11822|UniProtKB=P35625 P35625 TIMP3 PTHR11844:SF22 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 3 metalloendopeptidase activity#GO:0004222;peptidase inhibitor activity#GO:0030414;metallopeptidase activity#GO:0008237;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of catabolic process#GO:0009895;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=9675|UniProtKB=P28827 P28827 PTPRM PTHR19134:SF206 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=885|UniProtKB=O75882 O75882 ATRN PTHR10574:SF223 NETRIN/LAMININ-RELATED ATTRACTIN system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;tissue development#GO:0009888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 extracellular matrix protein#PC00102 HUMAN|HGNC=30267|UniProtKB=Q86YS3 Q86YS3 RAB11FIP4 PTHR15726:SF5 RAB11-FAMILY INTERACTING PROTEIN RAB11 FAMILY-INTERACTING PROTEIN 4 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 endosomal transport#GO:0016197;cellular localization#GO:0051641;cell division#GO:0051301;membrane fission#GO:0090148;membrane organization#GO:0061024;transport#GO:0006810;cell cycle process#GO:0022402;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cell division#GO:0051302;regulation of cell cycle process#GO:0010564;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of cytokinesis#GO:0032465;cytokinesis#GO:0000910 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;centrosome#GO:0005813;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;recycling endosome#GO:0055037;plasma membrane region#GO:0098590;cell division site#GO:0032153;microtubule organizing center#GO:0005815;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;centriole#GO:0005814;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;endomembrane system#GO:0012505;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=16697|UniProtKB=Q8WY21 Q8WY21 SORCS1 PTHR12106:SF8 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810 cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;integral component of membrane#GO:0016021;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=26484|UniProtKB=Q96MR9 Q96MR9 ZNF560 PTHR24381:SF44 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 560 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4122|UniProtKB=P34059 P34059 GALNS PTHR42693:SF33 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE G-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=28248|UniProtKB=P0CW24 P0CW24 PNMA6A PTHR23095:SF40 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 6A HUMAN|HGNC=7582|UniProtKB=P05976 P05976 MYL1 PTHR23048:SF3 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 1/3, SKELETAL MUSCLE ISOFORM actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=1620|UniProtKB=P40227 P40227 CCT6A PTHR11353:SF54 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ZETA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;chaperone complex#GO:0101031;cellular anatomical entity#GO:0110165;chaperonin-containing T-complex#GO:0005832;intracellular#GO:0005622 chaperonin#PC00073 HUMAN|HGNC=25155|UniProtKB=Q86XE5 Q86XE5 HOGA1 PTHR12128:SF15 DIHYDRODIPICOLINATE SYNTHASE 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL lyase#PC00144 Lysine biosynthesis#P02751>Dihydrodipicolinate synthase#P03008 HUMAN|HGNC=20439|UniProtKB=Q9BZI7 Q9BZI7 UPF3B PTHR13112:SF1 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN REGULATOR OF NONSENSE TRANSCRIPTS 3B RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=10947|UniProtKB=Q08357 Q08357 SLC20A2 PTHR11101:SF83 PHOSPHATE TRANSPORTER SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;inorganic anion transport#GO:0015698;anion transmembrane transport#GO:0098656 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=28357|UniProtKB=Q9H609 Q9H609 ZNF576 PTHR24408:SF54 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 316-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21918|UniProtKB=Q6P9H5 Q6P9H5 GIMAP6 PTHR10903:SF144 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 6 small GTPase#PC00208 HUMAN|HGNC=2255|UniProtKB=Q92828 Q92828 CORO2A PTHR10856:SF2 CORONIN CORONIN-2A cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 non-motor actin binding protein#PC00165 HUMAN|HGNC=18101|UniProtKB=Q5J5C9 Q5J5C9 DEFB121 PTHR15001:SF8 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 121 antimicrobial response protein#PC00051 HUMAN|HGNC=18860|UniProtKB=Q9NR71 Q9NR71 ASAH2 PTHR12670:SF1 CERAMIDASE NEUTRAL CERAMIDASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;long-chain fatty acid metabolic process#GO:0001676;organic hydroxy compound metabolic process#GO:1901615;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;monocarboxylic acid metabolic process#GO:0032787;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=4405|UniProtKB=P63215 P63215 GNG3 PTHR13809:SF11 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-3 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 HUMAN|HGNC=19611|UniProtKB=Q8NH10 Q8NH10 OR8U1 PTHR48018:SF91 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=28642|UniProtKB=Q8NEA5 Q8NEA5 C19orf18 PTHR38000:SF1 RIKEN CDNA 2900092C05 RIKEN CDNA 2900092C05 GENE HUMAN|HGNC=19832|UniProtKB=Q86T13 Q86T13 CLEC14A PTHR14789:SF5 CHONDROLECTIN VARIANT CHODLFDELTAE. C-TYPE LECTIN DOMAIN FAMILY 14 MEMBER A extracellular matrix binding#GO:0050840;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;extracellular matrix#GO:0031012;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=18445|UniProtKB=Q96GE6 Q96GE6 CALML4 PTHR23050:SF169 CALCIUM BINDING PROTEIN CALMODULIN-LIKE PROTEIN 4 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 calmodulin-related#PC00061 HUMAN|HGNC=977|UniProtKB=O15382 O15382 BCAT2 PTHR11825:SF39 SUBGROUP IIII AMINOTRANSFERASE BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE, MITOCHONDRIAL transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;branched-chain amino acid biosynthetic process#GO:0009082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transaminase#PC00216 Alanine biosynthesis#P02724>Branched chain amino acid aminotransferase#P02815;Leucine biosynthesis#P02749>Branched chain amino acid aminotransferase#P03000;Valine biosynthesis#P02785>Branched chain amino acid aminotransferase#P03215;Isoleucine biosynthesis#P02748>Branched chain amino acid aminotransferase#P02994 HUMAN|HGNC=29218|UniProtKB=Q9ULL0 Q9ULL0 KIAA1210 PTHR47743:SF2 KIAA1210 / KIAA1211 FAMILY MEMBER ACROSOMAL PROTEIN KIAA1210 HUMAN|HGNC=25760|UniProtKB=Q8IV32 Q8IV32 CCDC71 PTHR14484:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 HUMAN|HGNC=3010|UniProtKB=P42658 P42658 DPP6 PTHR11731:SF20 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL AMINOPEPTIDASE-LIKE PROTEIN 6 serine protease#PC00203 HUMAN|HGNC=5344|UniProtKB=P05362 P05362 ICAM1 PTHR13771:SF18 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=28631|UniProtKB=Q8N129 Q8N129 CNPY4 PTHR15382:SF3 CTG4A-RELATED PROTEIN CANOPY HOMOLOG 4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=23598|UniProtKB=Q6L8H2 Q6L8H2 KRTAP5-3 PTHR23262:SF202 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-3 HUMAN|HGNC=15462|UniProtKB=Q9Y3S2 Q9Y3S2 ZNF330 PTHR13214:SF1 ZINC FINGER PROTEIN 330 ZINC FINGER PROTEIN 330 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=20820|UniProtKB=Q8NHX9 Q8NHX9 TPCN2 PTHR46768:SF1 TWO PORE CALCIUM CHANNEL PROTEIN 2 TWO PORE CALCIUM CHANNEL PROTEIN 2 ion channel#PC00133 CCKR signaling map#P06959>TPC1/2#P07209 HUMAN|HGNC=5039|UniProtKB=P52597 P52597 HNRNPF PTHR13976:SF32 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN F nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=11250|UniProtKB=Q9Y5K1 Q9Y5K1 SPO11 PTHR10848:SF0 MEIOTIC RECOMBINATION PROTEIN SPO11 MEIOTIC RECOMBINATION PROTEIN SPO11 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;endodeoxyribonuclease activity#GO:0004520;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;deoxyribonuclease activity#GO:0004536 endodeoxyribonuclease#PC00093 HUMAN|HGNC=914|UniProtKB=P61769 P61769 B2M PTHR19944:SF62 MHC CLASS II-RELATED BETA-2-MICROGLOBULIN major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 HUMAN|HGNC=35154|UniProtKB=A6NCF6 A6NCF6 MAGEA13P PTHR11736:SF85 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MAGE DOMAIN-CONTAINING PROTEIN MAGEA13P-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=19699|UniProtKB=Q9NYY3 Q9NYY3 PLK2 PTHR24345:SF44 SERINE/THREONINE-PROTEIN KINASE PLK SERINE/THREONINE-PROTEIN KINASE PLK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cell division#GO:0051301;membrane fission#GO:0090148;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;regulation of cell division#GO:0051302;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of cytokinesis#GO:0032465;cytokinesis#GO:0000910 spindle pole#GO:0000922;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=26588|UniProtKB=Q8N292 Q8N292 GAPT PTHR37350:SF1 PROTEIN GAPT PROTEIN GAPT HUMAN|HGNC=5030|UniProtKB=Q13151 Q13151 HNRNPA0 PTHR48024:SF2 GEO13361P1-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A0 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=33174|UniProtKB=Q5VSR9 Q5VSR9 SPANXN1 PTHR23425:SF7 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME N1 HUMAN|HGNC=1165|UniProtKB=Q9Y4D2 Q9Y4D2 DAGLA PTHR45792:SF8 DIACYLGLYCEROL LIPASE HOMOLOG-RELATED DIACYLGLYCEROL LIPASE-ALPHA lipase#PC00143 2-arachidonoylglycerol biosynthesis#P05726>DGL#P05736 HUMAN|HGNC=1364|UniProtKB=Q9NX38 Q9NX38 ABITRAM PTHR13651:SF0 UNCHARACTERIZED PROTEIN ABITRAM membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=18063|UniProtKB=Q9NQZ5 Q9NQZ5 STARD7 PTHR19308:SF8 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 7, MITOCHONDRIAL HUMAN|HGNC=21900|UniProtKB=Q9NXW9 Q9NXW9 ALKBH4 PTHR12463:SF0 OXYGENASE-RELATED ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 4 demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidation-reduction process#GO:0055114;demethylation#GO:0070988;oxidative demethylation#GO:0070989;metabolic process#GO:0008152 oxygenase#PC00177 HUMAN|HGNC=16379|UniProtKB=Q8IYM9 Q8IYM9 TRIM22 PTHR24103:SF650 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM22 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;protein homodimerization activity#GO:0042803;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;identical protein binding#GO:0042802;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;kinase binding#GO:0019900 regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;aromatic compound biosynthetic process#GO:0019438;positive regulation of autophagy#GO:0010508;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=42955|UniProtKB=A6NDI0 A6NDI0 TRIM49B PTHR24103:SF615 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 49B-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=16767|UniProtKB=Q8TCU5 Q8TCU5 GRIN3A PTHR18966:SF397 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3A amino acid binding#GO:0016597;cation channel activity#GO:0005261;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;neurotransmitter receptor activity#GO:0030594;voltage-gated cation channel activity#GO:0022843;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;glutamate binding#GO:0016595;ligand-gated channel activity#GO:0022834 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;ionotropic glutamate receptor signaling pathway#GO:0035235;cellular process#GO:0009987;signaling#GO:0023052;glutamate receptor signaling pathway#GO:0007215 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Ionotropic glutamate receptor pathway#P00037>NR3#P01009;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 HUMAN|HGNC=26980|UniProtKB=A6NE01 A6NE01 FAM186A PTHR33590:SF2 GLUTENIN, HIGH MOLECULAR WEIGHT SUBUNIT PW212-RELATED PROTEIN PROTEIN FAM186A HUMAN|HGNC=15102|UniProtKB=P0DN81 P0DN81 OR13C7 PTHR26453:SF635 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C7-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=890|UniProtKB=Q13825 Q13825 AUH PTHR11941:SF12 ENOYL-COA HYDRATASE-RELATED METHYLGLUTACONYL-COA HYDRATASE, MITOCHONDRIAL lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 hydratase#PC00120 HUMAN|HGNC=4877|UniProtKB=Q9UBX0 Q9UBX0 HESX1 PTHR46966:SF1 HOMEOBOX EXPRESSED IN ES CELLS 1 HOMEOBOX EXPRESSED IN ES CELLS 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;forebrain development#GO:0030900;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;gland development#GO:0048732;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=2561|UniProtKB=P61073 P61073 CXCR4 PTHR10489:SF594 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 4 head development#GO:0060322;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;immune response#GO:0006955;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;brain development#GO:0007420;cellular process#GO:0009987;nervous system development#GO:0007399;system development#GO:0048731;immune system process#GO:0002376;response to stimulus#GO:0050896;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417 Axon guidance mediated by Slit/Robo#P00008>Cxcr4#P00351;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=8220|UniProtKB=Q8NGA1 Q8NGA1 OR1M1 PTHR48001:SF124 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1M1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=24044|UniProtKB=Q5TYM5 Q5TYM5 FAM72A PTHR31841:SF1 PROTEIN FAM72A-RELATED PROTEIN FAM72A-RELATED cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=14543|UniProtKB=Q9BYP7 Q9BYP7 WNK3 PTHR13902:SF47 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE/THREONINE-PROTEIN KINASE WNK3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;transferase activity, transferring phosphorus-containing groups#GO:0016772;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;transporter activity#GO:0005215;kinase activity#GO:0016301;channel activity#GO:0015267;protein kinase activity#GO:0004672;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;transferase activity#GO:0016740;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;protein serine/threonine kinase activity#GO:0004674;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890 regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of transmembrane transport#GO:0034764;divalent inorganic cation transport#GO:0072511;regulation of transmembrane transporter activity#GO:0022898;intracellular signal transduction#GO:0035556;regulation of transporter activity#GO:0032409;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;regulation of calcium ion transport#GO:0051924;cellular metabolic process#GO:0044237;positive regulation of transport#GO:0051050;cell communication#GO:0007154;negative regulation of transport#GO:0051051;ion transmembrane transport#GO:0034220;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;regulation of ion transport#GO:0043269;positive regulation of ion transport#GO:0043270;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;phosphate-containing compound metabolic process#GO:0006796;regulation of potassium ion transmembrane transport#GO:1901379;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;ion homeostasis#GO:0050801;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;positive regulation of ion transmembrane transporter activity#GO:0032414;homeostatic process#GO:0042592;protein phosphorylation#GO:0006468;cellular process#GO:0009987;chemical homeostasis#GO:0048878;positive regulation of calcium ion transport#GO:0051928;localization#GO:0051179;response to stimulus#GO:0050896;sodium ion transport#GO:0006814;positive regulation of transporter activity#GO:0032411;positive regulation of ion transmembrane transport#GO:0034767;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;sodium ion transmembrane transport#GO:0035725 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=29171|UniProtKB=Q6IPM2 Q6IPM2 IQCE PTHR22590:SF3 UNCHARACTERIZED IQ DOMAIN-CONTAINING PROTEIN E HUMAN|HGNC=13923|UniProtKB=O15213 O15213 WDR46 PTHR14085:SF3 WD-REPEAT PROTEIN BING4 WD REPEAT-CONTAINING PROTEIN 46 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 HUMAN|HGNC=16048|UniProtKB=O75474 O75474 FRAT2 PTHR35154:SF2 GBP PROTEIN GSK-3-BINDING PROTEIN FRAT2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=18523|UniProtKB=Q6VB84 Q6VB84 FOXD4L3 PTHR11829:SF381 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-LIKE 3-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|Gene=LORF2_HUMAN|UniProtKB=O00370 O00370 - PTHR25952:SF246 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN HUMAN|HGNC=2700|UniProtKB=O15075 O15075 DCLK1 PTHR24347:SF401 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE DCLK1 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=18484|UniProtKB=Q8NEJ0 Q8NEJ0 DUSP18 PTHR46495:SF2 DUAL SPECIFICITY PROTEIN PHOSPHATASE 21 DUAL SPECIFICITY PROTEIN PHOSPHATASE 18 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=11963|UniProtKB=Q8NFJ8 Q8NFJ8 BHLHE22 PTHR19290:SF52 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 22 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=5877|UniProtKB=P01703 P01703 IGLV1-40 PTHR23267:SF456 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 1-40-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=34032|UniProtKB=Q3KNS6 Q3KNS6 ZNF829 PTHR23226:SF280 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 829 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23537|UniProtKB=Q96HY7 Q96HY7 DHTKD1 PTHR23152:SF4 2-OXOGLUTARATE DEHYDROGENASE 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT DHKTD1, MITOCHONDRIAL-RELATED dehydrogenase#PC00092 TCA cycle#P00051>alphaketoglutarate Dehydrogenase#P01269 HUMAN|HGNC=1866|UniProtKB=Q12798 Q12798 CETN1 PTHR23050:SF218 CALCIUM BINDING PROTEIN CENTRIN-1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;organelle fission#GO:0048285;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 calmodulin-related#PC00061 HUMAN|HGNC=17384|UniProtKB=Q6ZNA4 Q6ZNA4 RNF111 PTHR16200:SF4 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE ARKADIA SMAD binding#GO:0046332;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;nucleobase-containing compound metabolic process#GO:0006139;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;regulation of cellular response to growth factor stimulus#GO:0090287;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;aromatic compound biosynthetic process#GO:0019438;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;response to growth factor#GO:0070848;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;signaling#GO:0023052;regulation of cellular response to transforming growth factor beta stimulus#GO:1903844;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cellular protein catabolic process#GO:0044257;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=2666|UniProtKB=Q14118 Q14118 DAG1 PTHR21559:SF22 DYSTROGLYCAN-RELATED DYSTROGLYCAN extracellular matrix binding#GO:0050840;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;muscle organ development#GO:0007517;neurogenesis#GO:0022008;cell projection organization#GO:0030030;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;muscle structure development#GO:0061061;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;tissue morphogenesis#GO:0048729;multicellular organismal process#GO:0032501;morphogenesis of an epithelium#GO:0002009;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;basolateral plasma membrane#GO:0016323;plasma membrane protein complex#GO:0098797;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;sarcolemma#GO:0042383;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=17312|UniProtKB=O14925 O14925 TIMM23 PTHR15371:SF0 TIM23 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM23-RELATED protein transmembrane transporter activity#GO:0008320;amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 amino acid transporter#PC00046 HUMAN|HGNC=9012|UniProtKB=Q9NZM6 Q9NZM6 PKD2L2 PTHR10877:SF47 POLYCYSTIN FAMILY MEMBER POLYCYSTIC KIDNEY DISEASE 2-LIKE 2 PROTEIN calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133 HUMAN|HGNC=13590|UniProtKB=Q86XK2 Q86XK2 FBXO11 PTHR22990:SF20 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 11 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;proteolysis#GO:0006508;cell death#GO:0008219;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=30520|UniProtKB=Q96BQ5 Q96BQ5 CCDC127 PTHR31958:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 127 COILED-COIL DOMAIN-CONTAINING PROTEIN 127 HUMAN|HGNC=10469|UniProtKB=O95197 O95197 RTN3 PTHR45799:SF4 RETICULON-LIKE PROTEIN RETICULON-3 HUMAN|HGNC=9995|UniProtKB=O14921 O14921 RGS13 PTHR10845:SF32 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 13 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 HUMAN|HGNC=29200|UniProtKB=Q9ULR5 Q9ULR5 PAIP2B PTHR13154:SF5 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2B translation regulator activity#GO:0045182 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=8604|UniProtKB=O95340 O95340 PAPSS2 PTHR11055:SF16 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167 HUMAN|HGNC=12647|UniProtKB=Q9BV40 Q9BV40 VAMP8 PTHR45701:SF7 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 8 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular#GO:0005622;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 HUMAN|HGNC=12208|UniProtKB=A0A0K0K1C4 A0A0K0K1C4 TRBV27 PTHR23268:SF110 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 27 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=13603|UniProtKB=Q8N531 Q8N531 FBXL6 PTHR16134:SF28 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX/LRR-REPEAT PROTEIN 6 HUMAN|HGNC=15313|UniProtKB=Q8NH51 Q8NH51 OR8K3 PTHR48018:SF28 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=12237|UniProtKB=A0A075B6L6 A0A075B6L6 TRBV7-3 PTHR23268:SF105 T-CELL RECEPTOR BETA CHAIN IGV DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=469|UniProtKB=Q01433 Q01433 AMPD2 PTHR11359:SF3 AMP DEAMINASE AMP DEAMINASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;AMP metabolic process#GO:0046033;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 deaminase#PC00088 HUMAN|HGNC=8999|UniProtKB=Q9UG56 Q9UG56 PISD PTHR10067:SF6 PHOSPHATIDYLSERINE DECARBOXYLASE PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 decarboxylase#PC00089 HUMAN|HGNC=27843|UniProtKB=Q5JU67 Q5JU67 CFAP157 PTHR31954:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 structural protein#PC00211 HUMAN|HGNC=30745|UniProtKB=Q96B18 Q96B18 DACT3 PTHR15919:SF1 DAPPER-RELATED DAPPER HOMOLOG 3 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=87|UniProtKB=Q9UKU7 Q9UKU7 ACAD8 PTHR43831:SF1 ISOBUTYRYL-COA DEHYDROGENASE ISOBUTYRYL-COA DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092 HUMAN|HGNC=22788|UniProtKB=A0PJY2 A0PJY2 FEZF1 PTHR24390:SF70 ZINC FINGER PROTEIN FEZ FAMILY ZINC FINGER PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15989|UniProtKB=Q8NEY1 Q8NEY1 NAV1 PTHR12784:SF3 STEERIN NEURON NAVIGATOR 1 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;microtubule cytoskeleton organization#GO:0000226;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron migration#GO:0001764;microtubule bundle formation#GO:0001578;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;generation of neurons#GO:0048699;cell migration#GO:0016477;locomotion#GO:0040011 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=9967|UniProtKB=P07949 P07949 RET PTHR24416:SF485 TYROSINE-PROTEIN KINASE RECEPTOR PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=30629|UniProtKB=Q6PJ21 Q6PJ21 SPSB3 PTHR12245:SF5 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3 HUMAN|HGNC=8261|UniProtKB=O76001 O76001 OR2J3 PTHR26453:SF641 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2J3 transmembrane signal receptor#PC00197 HUMAN|HGNC=18334|UniProtKB=Q6B0B8 Q6B0B8 TIGD3 PTHR19303:SF36 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 HUMAN|HGNC=16639|UniProtKB=Q9UQ35 Q9UQ35 SRRM2 PTHR34755:SF3 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED SERINE/ARGININE REPETITIVE MATRIX PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 HUMAN|HGNC=21444|UniProtKB=Q9BT76 Q9BT76 UPK3B PTHR15446:SF15 UROPLAKIN III UROPLAKIN-3B intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=23241|UniProtKB=Q8NB50 Q8NB50 ZFP62 PTHR24376:SF77 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 62 HOMOLOG DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=27638|UniProtKB=Q5VXT5 Q5VXT5 SYPL2 PTHR10306:SF8 SYNAPTOPHYSIN SYNAPTOPHYSIN-LIKE PROTEIN 2 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;syntaxin-1 binding#GO:0017075 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=21335|UniProtKB=Q9Y5W8 Q9Y5W8 SNX13 PTHR22775:SF3 SORTING NEXIN SORTING NEXIN-13 scaffold/adaptor protein#PC00226 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS-PX1#P00706 HUMAN|HGNC=17135|UniProtKB=Q8WXF3 Q8WXF3 RLN3 PTHR20968:SF0 ILGF DOMAIN-CONTAINING PROTEIN RELAXIN-3 HUMAN|HGNC=19662|UniProtKB=Q7RTV2 Q7RTV2 GSTA5 PTHR11571:SF245 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE A5 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;sulfur compound metabolic process#GO:0006790;cellular response to chemical stimulus#GO:0070887;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;response to stimulus#GO:0050896;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular#GO:0005622;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982 transferase#PC00220 HUMAN|HGNC=25787|UniProtKB=Q96BT3 Q96BT3 CENPT PTHR46904:SF1 CENTROMERE PROTEIN T CENTROMERE PROTEIN T protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cellular protein-containing complex assembly#GO:0034622;kinetochore organization#GO:0051383;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;nuclear division#GO:0000280;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;cellular macromolecule localization#GO:0070727;protein localization to kinetochore#GO:0034501;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;protein localization to organelle#GO:0033365;kinetochore assembly#GO:0051382;protein-containing complex subunit organization#GO:0043933 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;condensed nuclear chromosome kinetochore#GO:0000778;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 HUMAN|HGNC=6901|UniProtKB=P48740 P48740 MASP1 PTHR24255:SF13 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED MANNAN-BINDING LECTIN SERINE PROTEASE 1 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=29510|UniProtKB=Q15390 Q15390 MTFR1 PTHR14215:SF1 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 1 cellular component organization or biogenesis#GO:0071840;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organelle organization#GO:0006996;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;organelle fission#GO:0048285;cellular metabolic process#GO:0044237;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial fission#GO:0000266;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18662|UniProtKB=Q9Y2V3 Q9Y2V3 RAX PTHR46271:SF3 HOMEOBOX PROTEIN, PUTATIVE-RELATED RETINAL HOMEOBOX PROTEIN RX homeodomain transcription factor#PC00119 HUMAN|HGNC=22969|UniProtKB=P60370 P60370 KRTAP10-5 PTHR23262:SF206 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-5 HUMAN|HGNC=6813|UniProtKB=Q9Y5V3 Q9Y5V3 MAGED1 PTHR11736:SF28 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN D1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9221|UniProtKB=Q01860 Q01860 POU5F1 PTHR11636:SF86 POU DOMAIN POU DOMAIN, CLASS 5, TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=16954|UniProtKB=Q92737 Q92737 RASL10A PTHR46350:SF3 RAS LIKE FAMILY 10 MEMBER B-RELATED RAS-LIKE PROTEIN FAMILY MEMBER 10A HUMAN|HGNC=19266|UniProtKB=Q6XYQ8 Q6XYQ8 SYT10 PTHR10024:SF46 SYNAPTOTAGMIN SYNAPTOTAGMIN-10 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;syntaxin binding#GO:0019905;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cation transport#GO:0006812;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;response to metal ion#GO:0010038;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of ion transport#GO:0043269;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=2495|UniProtKB=P56545 P56545 CTBP2 PTHR46029:SF3 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN 2 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 HUMAN|HGNC=10539|UniProtKB=Q12999 Q12999 TSPAN31 PTHR19282:SF3 TETRASPANIN TETRASPANIN-31 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=22567|UniProtKB=Q9H560 Q9H560 ANKRD19P PTHR24147:SF61 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 19-RELATED HUMAN|HGNC=31911|UniProtKB=Q8IZJ4 Q8IZJ4 RGL4 PTHR23113:SF223 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL-GDS-RELATED PROTEIN guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=9690|UniProtKB=O95997 O95997 PTTG1 PTHR10418:SF7 SECURIN-3 SECURIN negative regulation of sister chromatid segregation#GO:0033046;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;telophase#GO:0051326;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;M phase#GO:0000279;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of mitotic sister chromatid segregation#GO:0033047;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;negative regulation of cellular component organization#GO:0051129;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;meiosis I cell cycle phase#GO:0098764;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;cellular component organization#GO:0016043;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;regulation of chromosome separation#GO:1905818;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;cell cycle phase#GO:0022403;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;negative regulation of chromosome separation#GO:1905819;meiotic nuclear division#GO:0140013;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;biological phase#GO:0044848;cell cycle#GO:0007049;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25061|UniProtKB=Q6PI97 Q6PI97 C11orf88 PTHR47231:SF1 UPF0722 PROTEIN C11ORF88 PROTEIN HOATZ HUMAN|HGNC=12399|UniProtKB=Q9UBF9 Q9UBF9 MYOT PTHR45080:SF13 CONTACTIN 5 MYOTILIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;axon#GO:0030424 HUMAN|HGNC=19419|UniProtKB=Q8IZT8 Q8IZT8 HS3ST5 PTHR10605:SF46 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 5 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 HUMAN|HGNC=2988|UniProtKB=Q92608 Q92608 DOCK2 PTHR45653:SF6 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 2 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=16346|UniProtKB=Q8NHK3 Q8NHK3 KIR2DL5B PTHR11738:SF169 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 2DL5A-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=9275|UniProtKB=P35813 P35813 PPM1A PTHR47992:SF121 ALPHABET, ISOFORM E-RELATED PROTEIN PHOSPHATASE 1A regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;negative regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043124;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=54084|UniProtKB=P0CG12 P0CG12 DERPC PTHR28605:SF2 CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE) DECREASED EXPRESSION IN RENAL AND PROSTATE CANCER PROTEIN HUMAN|HGNC=30743|UniProtKB=Q969D9 Q969D9 TSLP PTHR38003:SF1 THYMIC STROMAL LYMPHOPOIETIN THYMIC STROMAL LYMPHOPOIETIN HUMAN|HGNC=10519|UniProtKB=Q9NZJ4 Q9NZJ4 SACS PTHR15600:SF37 SACSIN SACSIN heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488;chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544 HUMAN|HGNC=798|UniProtKB=O00244 O00244 ATOX1 PTHR46365:SF1 COPPER TRANSPORT PROTEIN ATOX1 COPPER TRANSPORT PROTEIN ATOX1 cation binding#GO:0043169;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;transition metal ion homeostasis#GO:0055076;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;cellular copper ion homeostasis#GO:0006878;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;biological regulation#GO:0065007;copper ion homeostasis#GO:0055070;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=6604|UniProtKB=Q8N6C8 Q8N6C8 LILRA3 PTHR11738:SF170 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 3-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=3671|UniProtKB=Q92915 Q92915 FGF14 PTHR11486:SF18 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 14 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=26854|UniProtKB=Q3ZCV2 Q3ZCV2 LEXM PTHR34914:SF1 LYMPHOCYTE EXPANSION MOLECULE LYMPHOCYTE EXPANSION MOLECULE HUMAN|HGNC=7671|UniProtKB=Q13772 Q13772 NCOA4 PTHR17085:SF5 NUCLEAR RECEPTOR COACTIVATOR 4 NUCLEAR RECEPTOR COACTIVATOR 4 response to organic substance#GO:0010033;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to chemical#GO:0042221 transcription cofactor#PC00217 HUMAN|HGNC=14037|UniProtKB=Q96A35 Q96A35 MRPL24 PTHR12903:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L24 39S RIBOSOMAL PROTEIN L24, MITOCHONDRIAL cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202 HUMAN|HGNC=92|UniProtKB=P49748 P49748 ACADVL PTHR43884:SF11 ACYL-COA DEHYDROGENASE VERY LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 HUMAN|HGNC=12120|UniProtKB=A0A075B6W5 A0A075B6W5 TRAV23DV6 PTHR19343:SF0 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 23/DELTA VARIABLE 6 HUMAN|HGNC=25937|UniProtKB=Q6IPW1 Q6IPW1 C11orf71 PTHR16445:SF0 SIMILAR TO HYPOTHETICAL PROTEIN FLJ20010 SIMILAR TO HYPOTHETICAL PROTEIN FLJ20010 HUMAN|HGNC=6264|UniProtKB=P48549 P48549 KCNJ3 PTHR11767:SF16 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;GABA-B receptor II signaling#P05731>K channel#P05758;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083 HUMAN|HGNC=9962|UniProtKB=Q92900 Q92900 UPF1 PTHR10887:SF364 DNA2/NAM7 HELICASE FAMILY REGULATOR OF NONSENSE TRANSCRIPTS 1 catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=35123|UniProtKB=A8MTJ6 A8MTJ6 FOXI3 PTHR11829:SF310 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN I3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=25360|UniProtKB=Q5T1V6 Q5T1V6 DDX59 PTHR47958:SF30 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX59-RELATED catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 HUMAN|HGNC=18123|UniProtKB=Q8NER5 Q8NER5 ACVR1C PTHR23255:SF58 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1C signaling receptor activity#GO:0038023;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;activin binding#GO:0048185;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 HUMAN|HGNC=35241|UniProtKB=A6NC57 A6NC57 ANKRD62 PTHR24147:SF29 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 62 HUMAN|HGNC=8238|UniProtKB=O76000 O76000 OR2B3 PTHR26453:SF103 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2B3-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=13067|UniProtKB=Q14593 Q14593 ZNF273 PTHR24384:SF201 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 273-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=21295|UniProtKB=Q8TE68 Q8TE68 EPS8L1 PTHR12287:SF19 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8-LIKE PROTEIN 1 Rho guanyl-nucleotide exchange factor activity#GO:0005089;cytoskeletal protein binding#GO:0008092;Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;actin binding#GO:0003779;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cell projection organization#GO:0030030;positive regulation of cell projection organization#GO:0031346;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;regulation of cellular component organization#GO:0051128;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;positive regulation of cellular component biogenesis#GO:0044089;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;Rho protein signal transduction#GO:0007266;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;plasma membrane bounded cell projection assembly#GO:0120031;regulation of Ras protein signal transduction#GO:0046578 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11450|UniProtKB=Q96I99 Q96I99 SUCLG2 PTHR11815:SF11 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;phosphorus metabolic process#GO:0006793;tricarboxylic acid cycle#GO:0006099;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;acyl-CoA metabolic process#GO:0006637;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 HUMAN|HGNC=28226|UniProtKB=Q9BRT9 Q9BRT9 GINS4 PTHR21206:SF0 SLD5 PROTEIN DNA REPLICATION COMPLEX GINS PROTEIN SLD5 pyrophosphatase activity#GO:0016462;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;pre-replicative complex#GO:0036387;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear pre-replicative complex#GO:0005656;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=6935|UniProtKB=P23508 P23508 MCC PTHR23347:SF4 COLORECTAL MUTANT CANCER PROTEIN MCC PROTEIN -RELATED COLORECTAL MUTANT CANCER PROTEIN HUMAN|HGNC=9025|UniProtKB=Q9Y446 Q9Y446 PKP3 PTHR10372:SF1 PLAKOPHILLIN-RELATED PLAKOPHILIN-3 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130 HUMAN|HGNC=2340|UniProtKB=P78560 P78560 CRADD PTHR15034:SF5 DEATH DOMAIN-CONTAINING PROTEIN CRADD DEATH DOMAIN-CONTAINING PROTEIN CRADD Apoptosis signaling pathway#P00006>RAIDD#P00294 HUMAN|HGNC=13581|UniProtKB=Q9UK22 Q9UK22 FBXO2 PTHR12125:SF11 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 2 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 HUMAN|HGNC=18761|UniProtKB=Q7Z2H8 Q7Z2H8 SLC36A1 PTHR22950:SF188 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 1 solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;proton transmembrane transporter activity#GO:0015078;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;proton transmembrane transport#GO:1902600;organic acid transport#GO:0015849;alanine transport#GO:0032328;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 amino acid transporter#PC00046 HUMAN|HGNC=3319|UniProtKB=Q99607 Q99607 ELF4 PTHR11849:SF170 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=21366|UniProtKB=Q4VXA5 Q4VXA5 KHDC1 PTHR31368:SF6 DEVELOPMENT PLURPOTENCY-ASSOCIATED PROTEIN 1/5 FAMILY MEMBER KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of cellular protein metabolic process#GO:0032270;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;positive regulation of cell death#GO:0010942;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9752|UniProtKB=P09417 P09417 QDPR PTHR15104:SF0 DIHYDROPTERIDINE REDUCTASE DIHYDROPTERIDINE REDUCTASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;NADP binding#GO:0050661;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;pteridine-containing compound metabolic process#GO:0042558;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;aromatic amino acid family metabolic process#GO:0009072;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=14514|UniProtKB=Q9BQC6 Q9BQC6 MRPL57 PTHR14520:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 63 RIBOSOMAL PROTEIN 63, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=12769|UniProtKB=O95388 O95388 CCN4 PTHR11348:SF4 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 4 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;biological adhesion#GO:0022610;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;regulation of cell death#GO:0010941;cell death#GO:0008219;biological regulation#GO:0065007;signaling#GO:0023052;negative regulation of cellular process#GO:0048523 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=18025|UniProtKB=Q5JTJ3 Q5JTJ3 COA6 PTHR46690:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG chaperone#PC00072 HUMAN|HGNC=21163|UniProtKB=Q14676 Q14676 MDC1 PTHR23196:SF34 PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN MEDIATOR OF DNA DAMAGE CHECKPOINT PROTEIN 1 HUMAN|HGNC=2765|UniProtKB=Q01524 Q01524 DEFA6 PTHR11876:SF3 ALPHA-DEFENSIN 1 DEFENSIN-6 response to external biotic stimulus#GO:0043207;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;antibacterial humoral response#GO:0019731;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;innate immune response#GO:0045087;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cellular response to biotic stimulus#GO:0071216;cellular process#GO:0009987;defense response to Gram-positive bacterium#GO:0050830;response to lipopolysaccharide#GO:0032496;defense response to Gram-negative bacterium#GO:0050829;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=9276|UniProtKB=O75688 O75688 PPM1B PTHR47992:SF105 ALPHABET, ISOFORM E-RELATED PROTEIN PHOSPHATASE 1B regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;negative regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043124;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=23589|UniProtKB=Q96F45 Q96F45 ZNF503 PTHR12522:SF3 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN 503 repressing transcription factor binding#GO:0070491;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12920|UniProtKB=P52737 P52737 ZNF136 PTHR24377:SF878 IP01015P-RELATED ZINC FINGER PROTEIN 136 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24609|UniProtKB=P08217 P08217 CELA2A PTHR24257:SF24 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 2A serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=3320|UniProtKB=Q9UKW6 Q9UKW6 ELF5 PTHR11849:SF15 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=9386|UniProtKB=Q9UGJ0 Q9UGJ0 PRKAG2 PTHR13780:SF122 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;cation binding#GO:0043169;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;response to nutrient levels#GO:0031667;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 HUMAN|HGNC=29327|UniProtKB=Q5VZ46 Q5VZ46 KIAA1614 PTHR14102:SF12 PAR-6-RELATED CDNA SEQUENCE BC034090 Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;kinase binding#GO:0019900 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of localization#GO:0032879;cellular component organization#GO:0016043;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;regulation of biological process#GO:0050789;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 tight junction#PC00214 HUMAN|HGNC=8175|UniProtKB=P30954 P30954 OR10J1 PTHR26451:SF344 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10J1 HUMAN|HGNC=4107|UniProtKB=O75459 O75459 PAGE1 PTHR14047:SF3 P ANTIGEN FAMILY MEMBER 5-RELATED P ANTIGEN FAMILY MEMBER 1 HUMAN|HGNC=23250|UniProtKB=Q6ZPD8 Q6ZPD8 DGAT2L6 PTHR12317:SF19 DIACYLGLYCEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 2-LIKE PROTEIN 6 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=4833|UniProtKB=P09105 P09105 HBQ1 PTHR11442:SF15 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT THETA-1 small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;intracellular#GO:0005622;extracellular region#GO:0005576 HUMAN|HGNC=3620|UniProtKB=O75015 O75015 FCGR3B PTHR11481:SF103 IMMUNOGLOBULIN FC RECEPTOR LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR III-A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=31287|UniProtKB=A6NDH6 A6NDH6 OR5H15 PTHR26452:SF135 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5H15 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=14587|UniProtKB=Q9NXR8 Q9NXR8 ING3 PTHR10333:SF99 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 3 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;N-acyltransferase activity#GO:0016410;modification-dependent protein binding#GO:0140030 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=6726|UniProtKB=Q99467 Q99467 CD180 PTHR24373:SF356 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN CD180 ANTIGEN response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;cellular response to lipopolysaccharide#GO:0071222;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to lipid#GO:0033993;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;response to molecule of bacterial origin#GO:0002237;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune effector process#GO:0002252;leukocyte activation#GO:0045321;B cell activation involved in immune response#GO:0002312;mononuclear cell proliferation#GO:0032943;response to organic substance#GO:0010033;lymphocyte activation involved in immune response#GO:0002285;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;lymphocyte activation#GO:0046649;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;lymphocyte proliferation#GO:0046651;cell communication#GO:0007154;cellular process#GO:0009987;cell activation involved in immune response#GO:0002263;response to lipopolysaccharide#GO:0032496;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to chemical#GO:0042221;leukocyte activation involved in immune response#GO:0002366;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of response to biotic stimulus#GO:0002833 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=5753|UniProtKB=P01593 P01593 IGKV1D-33 PTHR23267:SF452 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-33-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=17927|UniProtKB=Q9P0U3 Q9P0U3 SENP1 PTHR12606:SF30 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 1 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein-specific protease activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=8571|UniProtKB=Q9UNF0 Q9UNF0 PACSIN2 PTHR23065:SF14 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 regulation of endocytosis#GO:0030100;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;endocytosis#GO:0006897;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;vesicle organization#GO:0016050 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=31838|UniProtKB=Q9H321 Q9H321 VCX3B PTHR15251:SF2 TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED HUMAN|HGNC=25955|UniProtKB=Q8ND82 Q8ND82 ZNF280C PTHR24388:SF62 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 280C cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=30319|UniProtKB=Q86YR7 Q86YR7 MCF2L2 PTHR22826:SF201 RHO GUANINE EXCHANGE FACTOR-RELATED GUANINE NUCLEOTIDE EXCHANGE FACTOR MCF2L2-RELATED guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=9893|UniProtKB=P28749 P28749 RBL1 PTHR13742:SF20 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-LIKE PROTEIN 1 nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;activating transcription factor binding#GO:0033613;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;developmental process#GO:0032502;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;G1/S transition of mitotic cell cycle#GO:0000082;cell differentiation#GO:0030154;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;negative regulation of G1/S transition of mitotic cell cycle#GO:2000134;cellular developmental process#GO:0048869;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G1/S phase transition#GO:1902806 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromatin#GO:0000785;chromosome#GO:0005694;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway feedback loops 2#P04398>Rb#P04654 HUMAN|HGNC=837|UniProtKB=P30049 P30049 ATP5F1D PTHR13822:SF7 ATP SYNTHASE DELTA/EPSILON CHAIN ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide biosynthetic process#GO:0009152 ATP synthase#PC00002 HUMAN|HGNC=28249|UniProtKB=Q8IUZ5 Q8IUZ5 PHYKPL PTHR45688:SF6 FAMILY NOT NAMED 5-PHOSPHOHYDROXY-L-LYSINE PHOSPHO-LYASE cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11077|UniProtKB=Q6AI14 Q6AI14 SLC9A4 PTHR10110:SF103 SODIUM/HYDROGEN EXCHANGER SODIUM/HYDROGEN EXCHANGER 4 secondary carrier transporter#PC00258 HUMAN|HGNC=23408|UniProtKB=Q86YB7 Q86YB7 ECHDC2 PTHR11941:SF44 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 hydratase#PC00120 HUMAN|HGNC=33738|UniProtKB=Q86X51 Q86X51 EZHIP PTHR22467:SF3 UNCHARACTERIZED EZH INHIBITORY PROTEIN HUMAN|HGNC=13315|UniProtKB=Q9BY41 Q9BY41 HDAC8 PTHR48252:SF43 HISTONE DEACETYLASE 2-RELATED HISTONE DEACETYLASE 8 Wnt signaling pathway#P00057>Histone deacetylase#P01472 HUMAN|HGNC=9174|UniProtKB=P06746 P06746 POLB PTHR11276:SF1 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA-directed DNA polymerase activity#GO:0003887;catalytic activity, acting on DNA#GO:0140097;transferase activity#GO:0016740;DNA polymerase activity#GO:0034061;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA-directed DNA polymerase#PC00018 HUMAN|HGNC=16643|UniProtKB=Q14BN4 Q14BN4 SLMAP PTHR15715:SF22 CENTROSOMAL PROTEIN OF 170 KDA SARCOLEMMAL MEMBRANE-ASSOCIATED PROTEIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=11296|UniProtKB=P19623 P19623 SRM PTHR11558:SF11 SPERMIDINE/SPERMINE SYNTHASE SPERMIDINE SYNTHASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transferase#PC00220 HUMAN|HGNC=29159|UniProtKB=Q5SYB0 Q5SYB0 FRMPD1 PTHR46221:SF2 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=11283|UniProtKB=P12931 P12931 SRC PTHR24418:SF53 TYROSINE-PROTEIN KINASE PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;skeletal system development#GO:0001501;regulation of apoptotic signaling pathway#GO:2001233;cell population proliferation#GO:0008283;regulation of intracellular signal transduction#GO:1902531;hormone-mediated signaling pathway#GO:0009755;tissue remodeling#GO:0048771;regulation of biological process#GO:0050789;osteoclast differentiation#GO:0030316;cellular response to hormone stimulus#GO:0032870;bone remodeling#GO:0046849;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;innate immune response#GO:0045087;intracellular signal transduction#GO:0035556;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;epidermal growth factor receptor signaling pathway#GO:0007173;cellular response to endogenous stimulus#GO:0071495;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;interspecies interaction between organisms#GO:0044419;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular metabolic process#GO:0044237;cell communication#GO:0007154;programmed cell death#GO:0012501;cell adhesion#GO:0007155;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;multicellular organismal homeostasis#GO:0048871;response to stress#GO:0006950;leukocyte differentiation#GO:0002521;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;regulation of intrinsic apoptotic signaling pathway#GO:2001242;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;cellular response to steroid hormone stimulus#GO:0071383;animal organ development#GO:0048513;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of signaling#GO:0023051;biological adhesion#GO:0022610;hematopoietic or lymphoid organ development#GO:0048534;response to lipid#GO:0033993;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cellular response to lipid#GO:0071396;bone development#GO:0060348;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;cell differentiation#GO:0030154;system development#GO:0048731;response to endogenous stimulus#GO:0009719;tissue homeostasis#GO:0001894;negative regulation of programmed cell death#GO:0043069;bone resorption#GO:0045453;protein autophosphorylation#GO:0046777;intracellular steroid hormone receptor signaling pathway#GO:0030518;cell death#GO:0008219;hemopoiesis#GO:0030097;cellular response to organic cyclic compound#GO:0071407;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;myeloid cell differentiation#GO:0030099;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;steroid hormone mediated signaling pathway#GO:0043401;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;ERBB signaling pathway#GO:0038127;cell development#GO:0048468;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to hormone#GO:0009725;peptidyl-tyrosine modification#GO:0018212;response to chemical#GO:0042221;extrinsic apoptotic signaling pathway#GO:0097191;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;response to steroid hormone#GO:0048545;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 Gonadotropin-releasing hormone receptor pathway#P06664>SRC#P06844;Angiogenesis#P00005>Src#P00184;CCKR signaling map#P06959>p62 SRC#P07047;Integrin signalling pathway#P00034>Src#P00940;CCKR signaling map#P06959>SRC @Galphaq#P07163;Cadherin signaling pathway#P00012>Src#P00468;CCKR signaling map#P06959>SRC#P07202;CCKR signaling map#P06959>p60 SRC#P07207;Parkinson disease#P00049>Src kinase#P01230;CCKR signaling map#P06959>p54 SRC#P07109 HUMAN|HGNC=20448|UniProtKB=A6NKN8 A6NKN8 PCP4L1 PTHR15359:SF5 IG-LIKE DOMAIN-CONTAINING PROTEIN PURKINJE CELL PROTEIN 4-LIKE PROTEIN 1 HUMAN|HGNC=16029|UniProtKB=Q96PS8 Q96PS8 AQP10 PTHR43829:SF13 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-10 amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 HUMAN|HGNC=4661|UniProtKB=Q9UHL9 Q9UHL9 GTF2IRD1 PTHR46304:SF1 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1 GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 general transcription factor#PC00259 HUMAN|HGNC=8171|UniProtKB=Q8NGC4 Q8NGC4 OR10G3 PTHR26453:SF69 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G3 transmembrane signal receptor#PC00197 HUMAN|HGNC=940|UniProtKB=O95429 O95429 BAG4 PTHR12329:SF10 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 4 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234;chaperone binding#GO:0051087;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 biological regulation#GO:0065007;regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 Apoptosis signaling pathway#P00006>SODD#P00320 HUMAN|HGNC=3951|UniProtKB=Q16595 Q16595 FXN PTHR16821:SF4 FRATAXIN FRATAXIN, MITOCHONDRIAL cation binding#GO:0043169;ferrous iron binding#GO:0008198;ferroxidase activity#GO:0004322;metal cluster binding#GO:0051540;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;iron-sulfur cluster assembly#GO:0016226;cellular homeostasis#GO:0019725;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;iron ion homeostasis#GO:0055072;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;transition metal ion homeostasis#GO:0055076;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular iron ion homeostasis#GO:0006879;cellular ion homeostasis#GO:0006873;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular chemical homeostasis#GO:0055082;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 HUMAN|HGNC=101|UniProtKB=Q9UHC3 Q9UHC3 ASIC3 PTHR11690:SF228 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=11839|UniProtKB=Q04726 Q04726 TLE3 PTHR10814:SF24 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 3 repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein binding#GO:0005515;molecular function regulator#GO:0098772;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 HUMAN|HGNC=28378|UniProtKB=Q9BTM9 Q9BTM9 URM1 PTHR14986:SF4 RURM1 PROTEIN UBIQUITIN-RELATED MODIFIER 1 HUMAN|HGNC=24953|UniProtKB=O94992 O94992 HEXIM1 PTHR13469:SF7 HEXAMETHYLENE BISACETAMIDE INDUCIBLE 1 PROTEIN HEXIM1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;nucleic acid binding#GO:0003676;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;snRNA binding#GO:0017069;cyclin binding#GO:0030332;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase binding#GO:0019900;protein kinase activity#GO:0004672;RNA binding#GO:0003723;cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of cyclin-dependent protein kinase activity#GO:1904029;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of protein kinase activity#GO:0006469;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;nucleic acid-templated transcription#GO:0097659;regulation of protein kinase activity#GO:0045859;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of molecular function#GO:0044092 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25673|UniProtKB=P0C7W0 P0C7W0 PRR29 PTHR28604:SF1 FAMILY NOT NAMED PROLINE-RICH PROTEIN 29 HUMAN|Gene=LPPR1|UniProtKB=Q8TBJ4 Q8TBJ4 PLPPR1 PTHR10165:SF41 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphatase#PC00181 HUMAN|HGNC=24449|UniProtKB=Q9NPA8 Q9NPA8 ENY2 PTHR12514:SF1 ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR TRANSCRIPTION AND MRNA EXPORT FACTOR ENY2 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;chromatin binding#GO:0003682;binding#GO:0005488 cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;poly(A)+ mRNA export from nucleus#GO:0016973;protein modification by small protein conjugation or removal#GO:0070647;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;nuclear export#GO:0051168;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;protein modification by small protein removal#GO:0070646;protein transport#GO:0015031;protein deubiquitination#GO:0016579;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;intracellular transport#GO:0046907;regulation of metabolic process#GO:0019222;protein-containing complex localization#GO:0031503;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;transport#GO:0006810;nucleic acid transport#GO:0050657;protein modification process#GO:0036211;biosynthetic process#GO:0009058;ribonucleoprotein complex export from nucleus#GO:0071426;amide transport#GO:0042886;regulation of transcription, DNA-templated#GO:0006355;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone deubiquitination#GO:0016578;protein export from nucleus#GO:0006611;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;mRNA export from nucleus#GO:0006406;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;mRNA transport#GO:0051028;organic cyclic compound biosynthetic process#GO:1901362;ribonucleoprotein complex localization#GO:0071166;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;regulation of nucleic acid-templated transcription#GO:1903506;RNA export from nucleus#GO:0006405;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;histone acetyltransferase complex#GO:0000123;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DUBm complex#GO:0071819 DNA-binding transcription factor#PC00218 HUMAN|HGNC=34244|UniProtKB=Q5T4T1 Q5T4T1 TMEM170B PTHR22779:SF4 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 170B HUMAN|HGNC=8537|UniProtKB=Q99572 Q99572 P2RX7 PTHR10125:SF13 P2X PURINOCEPTOR P2X PURINOCEPTOR 7 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=9162|UniProtKB=Q9H307 Q9H307 PNN PTHR12707:SF0 PINN PININ catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=21034|UniProtKB=Q9P032 Q9P032 NDUFAF4 PTHR13338:SF6 UPF0240 PROTEIN NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 4 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5964|UniProtKB=Q13651 Q13651 IL10RA PTHR20859:SF43 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-10 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=12870|UniProtKB=P08048 P08048 ZFY PTHR24408:SF25 ZINC FINGER PROTEIN ZINC FINGER Y-CHROMOSOMAL PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25799|UniProtKB=Q8N442 Q8N442 GUF1 PTHR43512:SF4 TRANSLATION FACTOR GUF1-RELATED TRANSLATION FACTOR GUF1, MITOCHONDRIAL translation initiation factor#PC00224 HUMAN|HGNC=26954|UniProtKB=Q8NBR6 Q8NBR6 MINDY2 PTHR18063:SF8 NF-E2 INDUCIBLE PROTEIN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-2 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein K48-linked deubiquitination#GO:0071108;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;intracellular#GO:0005622 HUMAN|HGNC=24491|UniProtKB=Q86XG9 Q86XG9 NBPF5P PTHR14199:SF29 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 4-RELATED HUMAN|HGNC=25177|UniProtKB=Q96CP7 Q96CP7 TLCD1 PTHR13439:SF5 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;endomembrane system organization#GO:0010256;homeostatic process#GO:0042592;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=29409|UniProtKB=Q8TF61 Q8TF61 FBXO41 PTHR15739:SF4 ZINC FINGER PROTEIN F-BOX ONLY PROTEIN 41 HUMAN|HGNC=24534|UniProtKB=O76021 O76021 RSL1D1 PTHR23105:SF31 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=8156|UniProtKB=P35372 P35372 OPRM1 PTHR24229:SF7 NEUROPEPTIDES RECEPTOR MU-TYPE OPIOID RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;system process#GO:0003008;sensory perception of pain#GO:0019233;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Enkephalin release#P05913>GPCR (s)#P05975;Opioid proenkephalin pathway#P05915>Mu or Delta receptor#P05985;Opioid proopiomelanocortin pathway#P05917>Mu or Delta receptor#P06004 HUMAN|HGNC=17041|UniProtKB=O95757 O95757 HSPA4L PTHR45639:SF5 HSC70CB, ISOFORM G-RELATED HEAT SHOCK 70 KDA PROTEIN 4L cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4201|UniProtKB=Q92830 Q92830 KAT2A PTHR45750:SF1 GH11602P HISTONE ACETYLTRANSFERASE KAT2A HUMAN|HGNC=4005|UniProtKB=Q96I24 Q96I24 FUBP3 PTHR10288:SF234 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 3 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=33858|UniProtKB=Q4G0N7 Q4G0N7 FAM229B PTHR35355:SF2 PROTEIN FAM229A PROTEIN FAM229B HUMAN|HGNC=37204|UniProtKB=A6NJ08 A6NJ08 MBD3L5 PTHR12396:SF6 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 3-LIKE 2-RELATED HUMAN|HGNC=27421|UniProtKB=Q8N6V4 Q8N6V4 C10orf53 PTHR28448:SF1 UPF0728 PROTEIN C10ORF53 UPF0728 PROTEIN C10ORF53 HUMAN|HGNC=32264|UniProtKB=A6NEW6 A6NEW6 FAM90A17P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=39051|UniProtKB=B6SEH9 B6SEH9 ERVV-2 PTHR10424:SF74 VIRAL ENVELOPE PROTEIN ENDOGENOUS RETROVIRUS GROUP V MEMBER 1 ENV POLYPROTEIN-RELATED viral or transposable element protein#PC00237 HUMAN|HGNC=42325|UniProtKB=Q6P575 Q6P575 GUSBP11 PTHR10066:SF67 BETA-GLUCURONIDASE BETA-GLUCURONIDASE-RELATED oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carbohydrate metabolic process#GO:0005975;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 HUMAN|HGNC=9196|UniProtKB=P36954 P36954 POLR2I PTHR11239:SF1 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;DNA-templated transcription, elongation#GO:0006354;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;transcription elongation from RNA polymerase II promoter#GO:0006368;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 HUMAN|HGNC=26086|UniProtKB=Q5JRV8 Q5JRV8 TMEM255A PTHR33721:SF1 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 255A HUMAN|HGNC=34246|UniProtKB=A6NJL1 A6NJL1 ZSCAN5B PTHR23226:SF306 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 5B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=5294|UniProtKB=P41595 P41595 HTR2B PTHR24247:SF31 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2B cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=37270|UniProtKB=C9JQI7 C9JQI7 TMEM232 PTHR28651:SF1 TRANSMEMBRANE PROTEIN 232 TRANSMEMBRANE PROTEIN 232 HUMAN|Ensembl=ENSG00000284024|UniProtKB=A0A1W2PQ72 A0A1W2PQ72 HSPA14 PTHR47595:SF1 HEAT SHOCK 70 KDA PROTEIN 14 HEAT SHOCK 70 KDA PROTEIN 14 HUMAN|HGNC=5480|UniProtKB=P01880 P01880 IGHD PTHR23266:SF99 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY CONSTANT DELTA protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=11459|UniProtKB=O00204 O00204 SULT2B1 PTHR11783:SF9 SULFOTRANSFERASE SULT SULFOTRANSFERASE 2B1 transferase#PC00220 HUMAN|HGNC=8157|UniProtKB=Q99720 Q99720 SIGMAR1 PTHR10868:SF1 SIGMA 1-TYPE OPIOID RECEPTOR-RELATED SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=16390|UniProtKB=Q9Y239 Q9Y239 NOD1 PTHR24106:SF18 NACHT, LRR AND CARD DOMAINS-CONTAINING NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29527|UniProtKB=Q9Y241 Q9Y241 HIGD1A PTHR12297:SF5 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 1A, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7595|UniProtKB=Q9UBC5 Q9UBC5 MYO1A PTHR13140:SF291 MYOSIN UNCONVENTIONAL MYOSIN-IA pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;sensory perception of sound#GO:0007605;system process#GO:0003008;transport#GO:0006810;cellular component organization#GO:0016043;nervous system process#GO:0050877;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;sensory perception#GO:0007600;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 microvillus#GO:0005902;supramolecular complex#GO:0099080;brush border#GO:0005903;actin filament bundle#GO:0032432;cluster of actin-based cell projections#GO:0098862;actin-based cell projection#GO:0098858;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=23304|UniProtKB=Q96NZ9 Q96NZ9 PRAP1 PTHR37861:SF1 PROLINE-RICH ACIDIC PROTEIN 1 PROLINE-RICH ACIDIC PROTEIN 1 HUMAN|HGNC=16688|UniProtKB=O95070 O95070 YIF1A PTHR14083:SF2 YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN PROTEIN YIF1A localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=2334|UniProtKB=P17927 P17927 CR1 PTHR19325:SF545 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT RECEPTOR TYPE 1 HUMAN|HGNC=738|UniProtKB=P50553 P50553 ASCL1 PTHR13935:SF66 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;generation of neurons#GO:0048699;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 basic helix-loop-helix transcription factor#PC00055 Gonadotropin-releasing hormone receptor pathway#P06664>MASH1#P06826 HUMAN|HGNC=7898|UniProtKB=Q9UHC9 Q9UHC9 NPC1L1 PTHR45727:SF3 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC1-LIKE INTRACELLULAR CHOLESTEROL TRANSPORTER 1 HUMAN|HGNC=4725|UniProtKB=P0C0S8 P0C0S8 H2AC16 PTHR23430:SF245 HISTONE H2A HISTONE H2A TYPE 1 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=23725|UniProtKB=Q5T5U3 Q5T5U3 ARHGAP21 PTHR23175:SF16 FAMILY NOT NAMED RHO GTPASE-ACTIVATING PROTEIN 21 HUMAN|HGNC=493|UniProtKB=Q01484 Q01484 ANK2 PTHR24133:SF36 FAMILY NOT NAMED ANKYRIN-2 ion channel binding#GO:0044325;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=33904|UniProtKB=A6NK06 A6NK06 ACOD1 PTHR16943:SF11 2-METHYLCITRATE DEHYDRATASE-RELATED CIS-ACONITATE DECARBOXYLASE dehydratase#PC00091 HUMAN|Ensembl=ENSG00000286106|UniProtKB=A0A096LNW5 A0A096LNW5 ENSG00000286106 PTHR45836:SF15 SLIT HOMOLOG NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2-RELATED neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330;Notch signaling pathway#GO:0007219 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Notch signaling pathway#P00045>Notch#P01099;Angiogenesis#P00005>Notch#P00255;Notch signaling pathway#P00045>NIct#P01119;Alzheimer disease-presenilin pathway#P00004>Notch N-terminal fragment#P00171;Notch signaling pathway#P00045>NIcs#P01120;Notch signaling pathway#P00045>Ntm#P01114;Alzheimer disease-presenilin pathway#P00004>Notch C-terminal fragment#P00120;Notch signaling pathway#P00045>Next#P01103;Alzheimer disease-presenilin pathway#P00004>NICD#P00122;Alzheimer disease-presenilin pathway#P00004>Notch#P00176;Alzheimer disease-presenilin pathway#P00004>Notch fragment#P00154;Alzheimer disease-presenilin pathway#P00004>Notch transmembrane fragment#P00135;Alzheimer disease-presenilin pathway#P00004>Notch extracellular fragment#P00179 HUMAN|HGNC=6231|UniProtKB=Q14721 Q14721 KCNB1 PTHR11537:SF63 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=7703|UniProtKB=O95169 O95169 NDUFB8 PTHR12840:SF2 NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=29961|UniProtKB=P61366 P61366 OSTN PTHR35353:SF1 OSTEOCRIN OSTEOCRIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=20778|UniProtKB=P07437 P07437 TUBB PTHR11588:SF61 TUBULIN TUBULIN BETA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 HUMAN|HGNC=19192|UniProtKB=Q8N1I0 Q8N1I0 DOCK4 PTHR45653:SF7 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 4 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=18947|UniProtKB=Q3MIV0 Q3MIV0 KRTAP22-1 PTHR39653:SF2 KERATIN-ASSOCIATED PROTEIN 20-2 KERATIN-ASSOCIATED PROTEIN 22-1 HUMAN|HGNC=29116|UniProtKB=O94876 O94876 TMCC1 PTHR17613:SF11 CEREBRAL PROTEIN-11-RELATED TRANSMEMBRANE AND COILED-COIL DOMAINS PROTEIN 1 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane fission#GO:0090148;membrane organization#GO:0061024;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=5228|UniProtKB=P25686 P25686 DNAJB2 PTHR45168:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 2 DNAJ HOMOLOG SUBFAMILY B MEMBER 2 chaperone#PC00072 HUMAN|HGNC=11553|UniProtKB=Q01995 Q01995 TAGLN PTHR18959:SF40 CALPONIN/TRANSGELIN TRANSGELIN non-motor actin binding protein#PC00165 HUMAN|HGNC=10675|UniProtKB=Q99470 Q99470 SDF2 PTHR46809:SF3 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN STROMAL CELL-DERIVED FACTOR 2 HUMAN|HGNC=24837|UniProtKB=Q9UK00 Q9UK00 C3orf18 PTHR15868:SF0 SIMILAR TO RIKEN CDNA 6430571L13 GENE, SIMILAR TO G20 PROTEIN SIMILAR TO RIKEN CDNA 6430571L13 GENE; SIMILAR TO G20 PROTEIN HUMAN|HGNC=3474|UniProtKB=P62508 P62508 ESRRG PTHR48092:SF10 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN-RELATED RECEPTOR GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=29931|UniProtKB=Q9BVP2 Q9BVP2 GNL3 PTHR11089:SF11 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=30653|UniProtKB=Q7Z7C7 Q7Z7C7 STRA8 PTHR35254:SF1 STIMULATED BY RETINOIC ACID GENE 8 PROTEIN HOMOLOG STIMULATED BY RETINOIC ACID GENE 8 PROTEIN HOMOLOG HUMAN|HGNC=18243|UniProtKB=Q8NDN9 Q8NDN9 RCBTB1 PTHR22870:SF224 REGULATOR OF CHROMOSOME CONDENSATION RCC1 AND BTB DOMAIN-CONTAINING PROTEIN 1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=20570|UniProtKB=Q96S94 Q96S94 CCNL2 PTHR10026:SF45 CYCLIN CYCLIN-L2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 kinase activator#PC00138 HUMAN|HGNC=28117|UniProtKB=Q9BTD8 Q9BTD8 RBM42 PTHR24012:SF685 RNA BINDING PROTEIN RNA-BINDING MOTIF PROTEIN, Y CHROMOSOME, FAMILY 1 MEMBER C-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=4066|UniProtKB=Q13480 Q13480 GAB1 PTHR45960:SF5 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 1 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Grb2#P01148;EGF receptor signaling pathway#P00018>Gab#P00563 HUMAN|HGNC=15014|UniProtKB=Q8NGY9 Q8NGY9 OR2L8 PTHR26453:SF632 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2L8 transmembrane signal receptor#PC00197 HUMAN|HGNC=10590|UniProtKB=Q9NY46 Q9NY46 SCN3A PTHR10037:SF237 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 3 SUBUNIT ALPHA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sodium channel activity#GO:0005272;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;sodium ion transport#GO:0006814;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=6357|UniProtKB=P06870 P06870 KLK1 PTHR24271:SF47 KALLIKREIN-RELATED KALLIKREIN-1 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=23186|UniProtKB=Q14677 Q14677 CLINT1 PTHR12276:SF83 EPSIN/ENT-RELATED CLATHRIN INTERACTOR 1 protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 HUMAN|HGNC=30740|UniProtKB=Q9BW92 Q9BW92 TARS2 PTHR11451:SF27 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=5382|UniProtKB=O75874 O75874 IDH1 PTHR11822:SF28 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;secondary alcohol metabolic process#GO:1902652;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;NADP metabolic process#GO:0006739;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 HUMAN|HGNC=27009|UniProtKB=Q8TCI5 Q8TCI5 PIFO PTHR31508:SF2 PROTEIN PITCHFORK PROTEIN PITCHFORK cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;cellular component organization#GO:0016043;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987 microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=19763|UniProtKB=Q8WXK4 Q8WXK4 ASB12 PTHR24120:SF8 GH07239P ANKYRIN REPEAT AND SOCS BOX PROTEIN 12 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=25734|UniProtKB=Q8WV60 Q8WV60 PTCD2 PTHR14700:SF0 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, MITOCHONDRIAL PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, MITOCHONDRIAL nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of mRNA processing#GO:0050684;mitochondrion organization#GO:0007005;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;mRNA processing#GO:0006397;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17770|UniProtKB=Q6GYQ0 Q6GYQ0 RALGAPA1 PTHR10063:SF3 TUBERIN RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 HUMAN|HGNC=24684|UniProtKB=Q8N302 Q8N302 AGGF1 PTHR23106:SF24 ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1 ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1 HUMAN|HGNC=28569|UniProtKB=Q8N635 Q8N635 MEIOB PTHR21166:SF3 UNCHARACTERIZED MEIOSIS-SPECIFIC WITH OB DOMAIN-CONTAINING PROTEIN 3'-5'-exodeoxyribonuclease activity#GO:0008296;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;single-stranded DNA binding#GO:0003697;exonuclease activity#GO:0004527;deoxyribonuclease activity#GO:0004536;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;exodeoxyribonuclease activity#GO:0004529;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408;exodeoxyribonuclease activity, producing 5'-phosphomonoesters#GO:0016895 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;meiotic chromosome separation#GO:0051307;M phase#GO:0000279;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;meiosis I cell cycle phase#GO:0098764;chromosome separation#GO:0051304;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;resolution of meiotic recombination intermediates#GO:0000712;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;cell cycle#GO:0007049;organelle fission#GO:0048285;biological phase#GO:0044848;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 HUMAN|HGNC=23818|UniProtKB=Q14684 Q14684 RRP1B PTHR13026:SF2 NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52 RIBOSOMAL RNA PROCESSING PROTEIN 1 HOMOLOG B cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=23807|UniProtKB=Q9NXG2 Q9NXG2 THUMPD1 PTHR13452:SF15 THUMP DOMAIN CONTAINING PROTEIN 1-RELATED THUMP DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=11424|UniProtKB=O43815 O43815 STRN PTHR15653:SF2 STRIATIN STRIATIN phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein-containing complex binding#GO:0044877;protein phosphatase binding#GO:0019903;binding#GO:0005488 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;plasma membrane region#GO:0098590;dendrite#GO:0030425;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=11150|UniProtKB=P08621 P08621 SNRNP70 PTHR13952:SF5 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=11439|UniProtKB=Q12846 Q12846 STX4 PTHR19957:SF97 SYNTAXIN SYNTAXIN-4 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;vesicle organization#GO:0016050;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;export from cell#GO:0140352 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 HUMAN|HGNC=19264|UniProtKB=Q8NBV8 Q8NBV8 SYT8 PTHR10024:SF249 SYNAPTOTAGMIN SYNAPTOTAGMIN-8 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;syntaxin binding#GO:0019905;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;synaptic signaling#GO:0099536;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;neurotransmitter secretion#GO:0007269;response to inorganic substance#GO:0010035;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;exocytic process#GO:0140029;cellular component organization or biogenesis#GO:0071840;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;regulation of neurotransmitter levels#GO:0001505;regulation of ion transport#GO:0043269;export from cell#GO:0140352;vesicle fusion#GO:0006906;regulation of signaling#GO:0023051;transport#GO:0006810;cation transport#GO:0006812;organic substance transport#GO:0071702;regulation of transport#GO:0051049;neurotransmitter transport#GO:0006836;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;response to metal ion#GO:0010038;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;response to chemical#GO:0042221;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 HUMAN|HGNC=20793|UniProtKB=Q9H2L5 Q9H2L5 RASSF4 PTHR22738:SF4 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 4 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25255|UniProtKB=A6NM62 A6NM62 LRRC53 PTHR24369:SF161 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 53 HUMAN|HGNC=14886|UniProtKB=Q9UDY4 Q9UDY4 DNAJB4 PTHR24078:SF288 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 4 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488;chaperone binding#GO:0051087 'de novo' protein folding#GO:0006458;cellular process#GO:0009987;chaperone-mediated protein folding#GO:0061077;protein folding#GO:0006457 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=30451|UniProtKB=Q6ZT89 Q6ZT89 SLC25A48 PTHR45624:SF7 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 48 ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic cation transport#GO:0015695;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812 transporter#PC00227 HUMAN|HGNC=4213|UniProtKB=Q96MZ0 Q96MZ0 GDAP1L1 PTHR44188:SF2 GDAP1, ISOFORM A GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 1-LIKE 1 mitochondrial fusion#GO:0008053;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;organelle fusion#GO:0048284;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;peptide transport#GO:0015833;protein localization#GO:0008104;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular transport#GO:0046907;mitochondrial fission#GO:0000266 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;integral component of mitochondrial outer membrane#GO:0031307 HUMAN|HGNC=18044|UniProtKB=Q99624 Q99624 SLC38A3 PTHR22950:SF22 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;basic amino acid transmembrane transporter activity#GO:0015174;cation transmembrane transporter activity#GO:0008324;amide transmembrane transporter activity#GO:0042887;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;monocarboxylic acid transport#GO:0015718;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;basic amino acid transport#GO:0015802;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 amino acid transporter#PC00046 HUMAN|HGNC=31922|UniProtKB=O15083 O15083 ERC2 PTHR18861:SF3 ELKS/RAB6-INTERACTING/CAST PROTEIN ERC PROTEIN 2 membrane traffic protein#PC00150 HUMAN|HGNC=29980|UniProtKB=Q6PIV2 Q6PIV2 FOXR1 PTHR46789:SF1 FORKHEAD BOX PROTEIN R1 FORKHEAD BOX PROTEIN R1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=8283|UniProtKB=P47893 P47893 OR3A2 PTHR48001:SF139 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A2 transmembrane signal receptor#PC00197 HUMAN|HGNC=23086|UniProtKB=Q70EK9 Q70EK9 USP51 PTHR21646:SF38 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 51 cysteine protease#PC00081 HUMAN|HGNC=7957|UniProtKB=P49146 P49146 NPY2R PTHR24235:SF20 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 2 G-protein coupled receptor#PC00021 HUMAN|HGNC=7098|UniProtKB=Q07325 Q07325 CXCL9 PTHR10179:SF44 CXC CHEMOKINE C-X-C MOTIF CHEMOKINE 9 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=29618|UniProtKB=Q6UXG2 Q6UXG2 ELAPOR1 PTHR22727:SF13 PROTEIN CBG13728 ENDOSOME/LYSOSOME-ASSOCIATED APOPTOSIS AND AUTOPHAGY REGULATOR 1 HUMAN|HGNC=5116|UniProtKB=P09067 P09067 HOXB5 PTHR45659:SF2 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=37167|UniProtKB=P0CJ77 P0CJ77 MTRNR2L10 PTHR33895:SF3 HUMANIN-LIKE 4 HUMANIN-LIKE 10 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=39433|UniProtKB=P0CW18 P0CW18 PRSS56 PTHR24278:SF32 COAGULATION FACTOR SERINE PROTEASE 56 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=31749|UniProtKB=Q8WW36 Q8WW36 ZCCHC13 PTHR23002:SF53 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 13 single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;positive regulation of cellular protein metabolic process#GO:0032270;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=29866|UniProtKB=O94856 O94856 NFASC PTHR44170:SF12 PROTEIN SIDEKICK NEUROFASCIN HUMAN|HGNC=21679|UniProtKB=Q2MKA7 Q2MKA7 RSPO1 PTHR46987:SF5 FAMILY NOT NAMED R-SPONDIN-1 HUMAN|HGNC=5961|UniProtKB=Q9Y6K9 Q9Y6K9 IKBKG PTHR31553:SF3 NF-KAPPA-B ESSENTIAL MODULATOR NF-KAPPA-B ESSENTIAL MODULATOR protein binding#GO:0005515;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 HUMAN|HGNC=30884|UniProtKB=Q8IWB9 Q8IWB9 TEX2 PTHR13466:SF2 TEX2 PROTEIN-RELATED TESTIS-EXPRESSED PROTEIN 2 lipid binding#GO:0008289;binding#GO:0005488 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=1239|UniProtKB=Q9BXS4 Q9BXS4 TMEM59 PTHR28652:SF3 TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN TRANSMEMBRANE PROTEIN 59 regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;cellular metabolic process#GO:0044237;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;positive regulation of metabolic process#GO:0009893;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;catabolic process#GO:0009056;positive regulation of autophagy#GO:0010508;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of cellular metabolic process#GO:0031323 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=14121|UniProtKB=Q9Y2Y1 Q9Y2Y1 POLR3K PTHR11239:SF12 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=53648|UniProtKB=A0A1W2PR48 A0A1W2PR48 TLE7 PTHR10814:SF19 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 7 repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein binding#GO:0005515;molecular function regulator#GO:0098772;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 HUMAN|HGNC=29914|UniProtKB=P57740 P57740 NUP107 PTHR13003:SF2 NUP107-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP107 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;protein import#GO:0017038;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;nuclear export#GO:0051168;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;protein transport#GO:0015031;aromatic compound biosynthetic process#GO:0019438;intracellular transport#GO:0046907;regulation of metabolic process#GO:0019222;protein-containing complex localization#GO:0031503;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;biosynthetic process#GO:0009058;ribonucleoprotein complex export from nucleus#GO:0071426;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transcription, DNA-templated#GO:0006355;protein import into nucleus#GO:0006606;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;organic cyclic compound metabolic process#GO:1901360;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;protein export from nucleus#GO:0006611;protein localization to organelle#GO:0033365;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;mRNA export from nucleus#GO:0006406;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;establishment of protein localization to organelle#GO:0072594;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;ribonucleoprotein complex localization#GO:0071166;organic cyclic compound biosynthetic process#GO:1901362;mRNA transport#GO:0051028;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;nucleocytoplasmic transport#GO:0006913;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;regulation of nucleic acid-templated transcription#GO:1903506;RNA export from nucleus#GO:0006405;regulation of cellular macromolecule biosynthetic process#GO:2000112;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=13741|UniProtKB=Q9NY99 Q9NY99 SNTG2 PTHR10554:SF3 SYNTROPHIN GAMMA-2-SYNTROPHIN membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 HUMAN|HGNC=46|UniProtKB=Q2M3G0 Q2M3G0 ABCB5 PTHR24221:SF217 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 5 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;phospholipid transporter activity#GO:0005548;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;cellular process#GO:0009987;lipid transport#GO:0006869;amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=29300|UniProtKB=Q63ZY3 Q63ZY3 KANK2 PTHR24168:SF0 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2 cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;cellular response to hormone stimulus#GO:0032870;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cell communication#GO:0010648;protein-containing complex subunit organization#GO:0043933;cellular response to extracellular stimulus#GO:0031668;cellular protein-containing complex assembly#GO:0034622;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of signaling#GO:0023057;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cell cycle phase transition#GO:0044770;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;negative regulation of signal transduction#GO:0009968;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cell cycle G1/S phase transition#GO:1902806;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;mitotic cell cycle phase transition#GO:0044772;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;response to lipid#GO:0033993;biosynthetic process#GO:0009058;negative regulation of cell cycle process#GO:0010948;cellular response to lipid#GO:0071396;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of protein-containing complex assembly#GO:0043254;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular response to organic cyclic compound#GO:0071407;regulation of actin cytoskeleton organization#GO:0032956;mitotic nuclear division#GO:0140014;regulation of actin filament-based process#GO:0032970;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein polymerization#GO:0032271;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;negative regulation of biosynthetic process#GO:0009890;regulation of cell population proliferation#GO:0042127;regulation of actin filament length#GO:0030832;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;response to hormone#GO:0009725;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;actin cytoskeleton organization#GO:0030036;regulation of mitotic cell cycle#GO:0007346;transcription by RNA polymerase II#GO:0006366;negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;response to extracellular stimulus#GO:0009991;cell population proliferation#GO:0008283;regulation of actin polymerization or depolymerization#GO:0008064;G1/S transition of mitotic cell cycle#GO:0000082;response to nutrient#GO:0007584;transcription, DNA-templated#GO:0006351;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;negative regulation of cellular component organization#GO:0051129;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;regulation of organelle organization#GO:0033043;RNA biosynthetic process#GO:0032774;regulation of response to stimulus#GO:0048583;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;response to organic cyclic compound#GO:0014070;cell cycle G1/S phase transition#GO:0044843;cellular response to steroid hormone stimulus#GO:0071383;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;mitotic cell cycle process#GO:1903047;regulation of transcription, DNA-templated#GO:0006355;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;intracellular steroid hormone receptor signaling pathway#GO:0030518;negative regulation of cell population proliferation#GO:0008285;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of G1/S transition of mitotic cell cycle#GO:2000134;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular macromolecule biosynthetic process#GO:0034645;regulation of response to external stimulus#GO:0032101;cellular response to chemical stimulus#GO:0070887;negative regulation of cell cycle phase transition#GO:1901988;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cellular biosynthetic process#GO:0044249;negative regulation of mitotic cell cycle#GO:0045930;steroid hormone mediated signaling pathway#GO:0043401;organic substance biosynthetic process#GO:1901576;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;cellular response to external stimulus#GO:0071496;protein polymerization#GO:0051258;organelle fission#GO:0048285;regulation of cellular macromolecule biosynthetic process#GO:2000112;response to steroid hormone#GO:0048545 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=19048|UniProtKB=Q8IZT6 Q8IZT6 ASPM PTHR22590:SF4 UNCHARACTERIZED ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN HUMAN|HGNC=5876|UniProtKB=A0A0B4J1U3 A0A0B4J1U3 IGLV1-36 PTHR23267:SF347 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 1-36 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=7225|UniProtKB=P25189 P25189 MPZ PTHR13869:SF7 MYELIN P0 RELATED MYELIN PROTEIN P0 myelin protein#PC00161 HUMAN|HGNC=25989|UniProtKB=Q9NXE8 Q9NXE8 CWC25 PTHR16196:SF0 CELL CYCLE CONTROL PROTEIN CWF25 PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=23523|UniProtKB=Q5VZ66 Q5VZ66 JAKMIP3 PTHR18935:SF9 UNCHARACTERIZED JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 3 HUMAN|HGNC=15034|UniProtKB=Q8NGY5 Q8NGY5 OR6N1 PTHR26453:SF596 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6N1 transmembrane signal receptor#PC00197 HUMAN|HGNC=23233|UniProtKB=Q8N428 Q8N428 GALNT16 PTHR11675:SF3 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 16 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=14051|UniProtKB=P82932 P82932 MRPS6 PTHR21011:SF1 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6 28S RIBOSOMAL PROTEIN S6, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 ribosomal protein#PC00202 HUMAN|HGNC=2476|UniProtKB=P01036 P01036 CST4 PTHR46186:SF3 CYSTATIN CYSTATIN-S-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=20779|UniProtKB=Q9H3R1 Q9H3R1 NDST4 PTHR10605:SF45 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE/N-SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;heparan sulfate proteoglycan metabolic process#GO:0030201;proteoglycan biosynthetic process#GO:0030166;cellular carbohydrate metabolic process#GO:0044262;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;cellular polysaccharide biosynthetic process#GO:0033692;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=23193|UniProtKB=Q9P2Z0 Q9P2Z0 THAP10 PTHR10725:SF68 THAP DOMAIN-CONTAINING PROTEIN 9 THAP DOMAIN-CONTAINING PROTEIN 10 HUMAN|HGNC=49394|UniProtKB=H3BNL8 H3BNL8 ARMH2 PTHR37679:SF1 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=4261|UniProtKB=P01241 P01241 GH1 PTHR11417:SF2 SOMATOTROPIN,PROLACTIN SOMATOTROPIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;response to extracellular stimulus#GO:0009991;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to hormone stimulus#GO:0032870;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of receptor signaling pathway via STAT#GO:1904894;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of growth#GO:0045927;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;tyrosine phosphorylation of STAT protein#GO:0007260;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to peptide hormone#GO:0043434;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;growth#GO:0040007;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of growth#GO:0040008;regulation of receptor signaling pathway via STAT#GO:1904892;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;response to nutrient levels#GO:0031667;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to hormone#GO:0009725;receptor signaling pathway via STAT#GO:0097696;peptidyl-tyrosine modification#GO:0018212;regulation of macromolecule metabolic process#GO:0060255;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 HUMAN|HGNC=18238|UniProtKB=P57735 P57735 RAB25 PTHR47979:SF8 DRAB11-RELATED RAS-RELATED PROTEIN RAB-25 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=1449|UniProtKB=P0DP25 P0DP25 CALM3 PTHR23050:SF473 CALCIUM BINDING PROTEIN CALMODULIN-3 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 HUMAN|HGNC=18636|UniProtKB=A5PLK6 A5PLK6 RGSL1 PTHR47079:SF1 REGULATOR OF G-PROTEIN SIGNALING PROTEIN-LIKE REGULATOR OF G-PROTEIN SIGNALING PROTEIN-LIKE HUMAN|HGNC=4597|UniProtKB=P41594 P41594 GRM5 PTHR24060:SF30 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 5 amino acid binding#GO:0016597;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888;glutamate receptor activity#GO:0008066;postsynaptic neurotransmitter receptor activity#GO:0098960;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;ion binding#GO:0043167;anion binding#GO:0043168;organic acid binding#GO:0043177;glutamate binding#GO:0016595 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;intrinsic component of membrane#GO:0031224;postsynaptic density membrane#GO:0098839;integral component of plasma membrane#GO:0005887;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Metabotropic glutamate receptor group III pathway#P00039>mGluR 1/5#P01040;Metabotropic glutamate receptor group I pathway#P00041>mGluR1#P01062;Metabotropic glutamate receptor group I pathway#P00041>mGluR5#P01061;Metabotropic glutamate receptor group III pathway#P00039>mGluR 5#P01037;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Endogenous cannabinoid signaling#P05730>mGluR#P05748 HUMAN|HGNC=12829|UniProtKB=O43543 O43543 XRCC2 PTHR46644:SF2 DNA REPAIR PROTEIN XRCC2 DNA REPAIR PROTEIN XRCC2 DNA metabolism protein#PC00009 HUMAN|HGNC=14508|UniProtKB=P82650 P82650 MRPS22 PTHR13071:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S22 28S RIBOSOMAL PROTEIN S22, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 HUMAN|HGNC=23434|UniProtKB=Q5T5M9 Q5T5M9 CCNJ PTHR10177:SF62 CYCLINS CYCLIN-J cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 HUMAN|HGNC=8677|UniProtKB=Q9Y5I4 Q9Y5I4 PCDHAC2 PTHR24028:SF119 CADHERIN-87A PROTOCADHERIN ALPHA-C2 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=31708|UniProtKB=Q9Y561 Q9Y561 LRP12 PTHR24270:SF47 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 12 apolipoprotein#PC00052 HUMAN|HGNC=18272|UniProtKB=Q6P1Q9 Q6P1Q9 METTL2B PTHR22809:SF4 METHYLTRANSFERASE-RELATED TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2A-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 methyltransferase#PC00155 HUMAN|HGNC=19845|UniProtKB=A4IF30 A4IF30 SLC35F4 PTHR19346:SF2 UNCHARACTERIZED SOLUTE CARRIER FAMILY 35 MEMBER F4 HUMAN|HGNC=23759|UniProtKB=Q96I13 Q96I13 ABHD8 PTHR42886:SF1 RE40534P-RELATED PROTEIN ABHD8 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=4135|UniProtKB=P07902 P07902 GALT PTHR11943:SF1 GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;uridylyltransferase activity#GO:0070569;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 monosaccharide metabolic process#GO:0005996;small molecule catabolic process#GO:0044282;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotidyltransferase#PC00174 Fructose galactose metabolism#P02744>Hexose 1-P uridyltransferase#P02964 HUMAN|HGNC=6705|UniProtKB=Q13449 Q13449 LSAMP PTHR42757:SF22 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED LIMBIC SYSTEM-ASSOCIATED MEMBRANE PROTEIN immunoglobulin#PC00123 HUMAN|HGNC=13102|UniProtKB=P17032 P17032 ZNF37A PTHR24377:SF828 IP01015P-RELATED ZINC FINGER PROTEIN 37A cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4927|UniProtKB=Q92504 Q92504 SLC39A7 PTHR16950:SF25 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER SLC39A7 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 primary active transporter#PC00068 HUMAN|HGNC=491|UniProtKB=Q9Y5C1 Q9Y5C1 ANGPTL3 PTHR19143:SF222 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 3 lipid metabolic process#GO:0006629;negative regulation of hydrolase activity#GO:0051346;triglyceride homeostasis#GO:0070328;regulation of lipase activity#GO:0060191;regulation of phospholipase activity#GO:0010517;lipid catabolic process#GO:0016042;phospholipid metabolic process#GO:0006644;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;organic substance catabolic process#GO:1901575;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phospholipid catabolic process#GO:0009395;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=44112|UniProtKB=H3BS89 H3BS89 TMEM178B PTHR32005:SF1 TRANSMEMBRANE PROTEIN 178B-RELATED TRANSMEMBRANE PROTEIN 178B cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=16861|UniProtKB=Q9Y6X2 Q9Y6X2 PIAS3 PTHR10782:SF10 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE PIAS3 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;RNA polymerase II transcription factor binding#GO:0001085;molecular function regulator#GO:0098772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;transcription factor binding#GO:0008134 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 JAK/STAT signaling pathway#P00038>PIAS#P01031;Interferon-gamma signaling pathway#P00035>PIAS#P00958 HUMAN|HGNC=28461|UniProtKB=Q9BVI4 Q9BVI4 NOC4L PTHR12455:SF0 NUCLEOLAR COMPLEX PROTEIN 4 NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 HUMAN|HGNC=2672|UniProtKB=P51397 P51397 DAP PTHR13177:SF3 DEATH-ASSOCIATED PROTEIN 1 DEATH-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;response to extracellular stimulus#GO:0009991;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;cellular response to starvation#GO:0009267;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;response to nutrient levels#GO:0031667;negative regulation of autophagy#GO:0010507;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;negative regulation of catabolic process#GO:0009895;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=28450|UniProtKB=Q8NC44 Q8NC44 RETREG2 PTHR20952:SF4 ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN RETICULOPHAGY REGULATOR 2 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=23252|UniProtKB=Q58HT5 Q58HT5 AWAT1 PTHR12317:SF16 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYL-COA WAX ALCOHOL ACYLTRANSFERASE 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=14716|UniProtKB=Q8NH07 Q8NH07 OR11H2 PTHR24242:SF201 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H1-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=17110|UniProtKB=Q8TE60 Q8TE60 ADAMTS18 PTHR13723:SF167 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 18 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=13826|UniProtKB=Q5VZB9 Q5VZB9 DMRTA1 PTHR12322:SF71 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;sex differentiation#GO:0007548;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;reproduction#GO:0000003;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=3708|UniProtKB=O43915 O43915 VEGFD PTHR12025:SF11 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR D receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein metabolic process#GO:0051246;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;positive regulation of protein modification process#GO:0031401;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;tube morphogenesis#GO:0035239;epithelial cell proliferation#GO:0050673;sprouting angiogenesis#GO:0002040;positive regulation of epithelial cell proliferation#GO:0050679;cellular protein metabolic process#GO:0044267;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;angiogenesis#GO:0001525;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;taxis#GO:0042330;signal transduction#GO:0007165;response to hypoxia#GO:0001666;positive regulation of angiogenesis#GO:0045766;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of leukocyte migration#GO:0002687;system development#GO:0048731;regulation of chemotaxis#GO:0050920;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;myeloid leukocyte migration#GO:0097529;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;response to oxygen levels#GO:0070482;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;positive regulation of immune system process#GO:0002684;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cell chemotaxis#GO:0060326;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;positive regulation of cellular component movement#GO:0051272;regulation of phosphorus metabolic process#GO:0051174;leukocyte migration#GO:0050900;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;nitrogen compound metabolic process#GO:0006807;vasculature development#GO:0001944;response to abiotic stimulus#GO:0009628;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;response to decreased oxygen levels#GO:0036293;tube development#GO:0035295;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;positive chemotaxis#GO:0050918;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;developmental process#GO:0032502;endothelial cell proliferation#GO:0001935;regulation of angiogenesis#GO:0045765;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;positive regulation of developmental process#GO:0051094;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of leukocyte chemotaxis#GO:0002690;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=5995|UniProtKB=Q9NPH3 Q9NPH3 IL1RAP PTHR11890:SF20 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 transmembrane signal receptor#PC00197 HUMAN|HGNC=4525|UniProtKB=Q9Y5X5 Q9Y5X5 NPFFR2 PTHR24241:SF132 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=30889|UniProtKB=Q96IX5 Q96IX5 ATP5MD PTHR34038:SF1 ATP SYNTHASE MEMBRANE SUBUNIT DAPIT, MITOCHONDRIAL ATP SYNTHASE MEMBRANE SUBUNIT DAPIT, MITOCHONDRIAL envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 HUMAN|HGNC=10301|UniProtKB=P62913 P62913 RPL11 PTHR11994:SF23 60S RIBOSOMAL PROTEIN L11-RELATED 60S RIBOSOMAL PROTEIN L11 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=30187|UniProtKB=Q9NRX6 Q9NRX6 TMEM167B PTHR46815:SF1 PROTEIN KISH-B PROTEIN KISH-B HUMAN|HGNC=16345|UniProtKB=Q8N109 Q8N109 KIR2DL5A PTHR11738:SF169 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 2DL5A-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=9039|UniProtKB=O60733 O60733 PLA2G6 PTHR24139:SF34 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 85/88 KDA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738 HUMAN|HGNC=11131|UniProtKB=O00161 O00161 SNAP23 PTHR19305:SF4 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 23 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;regulated exocytosis#GO:0045055;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular#GO:0005622;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 SNARE protein#PC00034 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 HUMAN|HGNC=20328|UniProtKB=Q6PH85 Q6PH85 DCUN1D2 PTHR12281:SF16 RP42 RELATED DCN1-LIKE PROTEIN 2 enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=24731|UniProtKB=Q8NBF2 Q8NBF2 NHLRC2 PTHR46388:SF2 NHL REPEAT-CONTAINING PROTEIN 2 NHL REPEAT-CONTAINING PROTEIN 2 HUMAN|HGNC=18697|UniProtKB=Q8N3C0 Q8N3C0 ASCC3 PTHR24075:SF6 SEC63 DOMAIN-CONTAINING ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3 nucleic acid binding#GO:0003676;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;DNA-dependent ATPase activity#GO:0008094;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;3'-5' DNA helicase activity#GO:0043138;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6883|UniProtKB=Q13387 Q13387 MAPK8IP2 PTHR11232:SF41 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 2 regulation of MAPK cascade#GO:0043408;signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;signal transduction by protein phosphorylation#GO:0023014;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;JNK cascade#GO:0007254;stress-activated MAPK cascade#GO:0051403;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;regulation of stress-activated MAPK cascade#GO:0032872;stress-activated protein kinase signaling cascade#GO:0031098;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9001|UniProtKB=Q00169 Q00169 PITPNA PTHR10658:SF28 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PHOSPHATIDYLINOSITOL TRANSFER PROTEIN ALPHA ISOFORM cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transporter#PC00227 HUMAN|HGNC=922|UniProtKB=Q9NPZ5 Q9NPZ5 B3GAT2 PTHR10896:SF8 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 2 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;chondroitin sulfate proteoglycan metabolic process#GO:0050654;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=21531|UniProtKB=Q8N3T1 Q8N3T1 GALNT15 PTHR11675:SF36 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 15 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=40039|UniProtKB=A8MUM7 A8MUM7 LGALS16 PTHR11346:SF166 GALECTIN GALECTIN-16 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=19858|UniProtKB=Q86TV6 Q86TV6 TTC7B PTHR23083:SF365 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT PROTEIN 7B protein localization to plasma membrane#GO:0072659;lipid metabolic process#GO:0006629;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;protein localization#GO:0008104;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;localization#GO:0051179;protein localization to cell periphery#GO:1990778;glycerolipid metabolic process#GO:0046486;cellular macromolecule localization#GO:0070727;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=927|UniProtKB=O60513 O60513 B4GALT4 PTHR19300:SF9 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 4 glycosyltransferase#PC00111 HUMAN|HGNC=14341|UniProtKB=Q8WWZ3 Q8WWZ3 EDARADD PTHR28469:SF1 ECTODYSPLASIN-A RECEPTOR-ASSOCIATED ADAPTER PROTEIN ECTODYSPLASIN-A RECEPTOR-ASSOCIATED ADAPTER PROTEIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=13291|UniProtKB=P60520 P60520 GABARAPL2 PTHR10969:SF4 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 2 response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;cell communication#GO:0007154;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;cellular process#GO:0009987;cellular response to stress#GO:0033554;cellular response to extracellular stimulus#GO:0031668 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=21566|UniProtKB=Q5JXM2 Q5JXM2 METTL24 PTHR32026:SF10 METHYLTRANSFERASE-LIKE PROTEIN 24 METHYLTRANSFERASE-LIKE PROTEIN 24 methyltransferase#PC00155 HUMAN|HGNC=3955|UniProtKB=P42685 P42685 FRK PTHR24418:SF373 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FRK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell population proliferation#GO:0008283;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;innate immune response#GO:0045087;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;peptidyl-tyrosine modification#GO:0018212;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 Axon guidance mediated by semaphorins#P00007>Fyn#P00335;Parkinson disease#P00049>Src kinase#P01230;Cadherin signaling pathway#P00012>Fyn#P00464;B cell activation#P00010>Blk#P00390;Integrin signalling pathway#P00034>Src#P00940;Parkinson disease#P00049>Fyn kinase#P01235 HUMAN|HGNC=9532|UniProtKB=P25788 P25788 PSMA3 PTHR11599:SF10 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-3 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome core complex, alpha-subunit complex#GO:0019773;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=10907|UniProtKB=P49279 P49279 SLC11A1 PTHR11706:SF52 SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;iron ion transmembrane transporter activity#GO:0005381;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=17287|UniProtKB=Q9H5I1 Q9H5I1 SUV39H2 PTHR46223:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2 N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone methylation#GO:0016571;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;histone lysine methylation#GO:0034968;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=30286|UniProtKB=Q96NL0 Q96NL0 RUNDC3B PTHR46251:SF1 RUN DOMAIN-CONTAINING 3 PROTEIN RUNDC3 RUN DOMAIN-CONTAINING PROTEIN 3B HUMAN|HGNC=18|UniProtKB=Q13685 Q13685 AAMP PTHR19857:SF17 MITOCHONDRIAL DIVISION PROTEIN 1-RELATED ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=18999|UniProtKB=Q9BVS4 Q9BVS4 RIOK2 PTHR45852:SF1 SER/THR-PROTEIN KINASE RIO2 SERINE/THREONINE-PROTEIN KINASE RIO2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;preribosome, small subunit precursor#GO:0030688;preribosome#GO:0030684;cytosol#GO:0005829;cellular anatomical entity#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=16207|UniProtKB=Q2PPJ7 Q2PPJ7 RALGAPA2 PTHR10063:SF2 TUBERIN RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 HUMAN|HGNC=15715|UniProtKB=Q66K74 Q66K74 MAP1S PTHR13843:SF11 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 1S cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;actin binding#GO:0003779;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cellular protein complex disassembly#GO:0043624;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;dendrite development#GO:0016358;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;cell morphogenesis involved in differentiation#GO:0000904;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;protein depolymerization#GO:0051261;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cytosol#GO:0005829;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cell body#GO:0044297;intracellular#GO:0005622;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;microtubule#GO:0005874;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=30615|UniProtKB=Q5M775 Q5M775 SPECC1 PTHR23167:SF3 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED CYTOSPIN-B cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856 HUMAN|HGNC=1984|UniProtKB=Q9NSE2 Q9NSE2 CISH PTHR10155:SF9 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT CYTOKINE-INDUCIBLE SH2-CONTAINING PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phosphorylation#GO:0016310;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 HUMAN|HGNC=13003|UniProtKB=Q13398 Q13398 ZNF211 PTHR24377:SF661 IP01015P-RELATED ZINC FINGER PROTEIN 211 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=30906|UniProtKB=O15195 O15195 VILL PTHR11977:SF30 VILLIN VILLIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=4132|UniProtKB=P47211 P47211 GALR1 PTHR24230:SF31 G-PROTEIN COUPLED RECEPTOR GALANIN RECEPTOR TYPE 1 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=28928|UniProtKB=Q86Y46 Q86Y46 KRT73 PTHR45616:SF31 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 73 HUMAN|HGNC=25202|UniProtKB=Q6P4D5 Q6P4D5 FAM122C PTHR22227:SF9 UNCHARACTERIZED PROTEIN FAM122C HUMAN|HGNC=26136|UniProtKB=Q9H706 Q9H706 GAREM1 PTHR14454:SF6 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 response to organic substance#GO:0010033;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 HUMAN|HGNC=6249|UniProtKB=Q9UJ96 Q9UJ96 KCNG2 PTHR11537:SF90 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY G MEMBER 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=15194|UniProtKB=Q8TCB6 Q8TCB6 OR51E1 PTHR26450:SF167 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51E1 transmembrane signal receptor#PC00197 HUMAN|HGNC=24923|UniProtKB=Q9Y5R4 Q9Y5R4 HEMK1 PTHR18895:SF74 HEMK METHYLTRANSFERASE MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE protein modifying enzyme#PC00260 HUMAN|HGNC=11466|UniProtKB=O75486 O75486 SUPT3H PTHR11380:SF16 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION PROTEIN SPT3 HOMOLOG nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 general transcription factor#PC00259 HUMAN|HGNC=12594|UniProtKB=Q15853 Q15853 USF2 PTHR46117:SF2 FI24210P1 UPSTREAM STIMULATORY FACTOR 2 PDGF signaling pathway#P00047>c-fos#P01145 HUMAN|HGNC=10722|UniProtKB=Q14242 Q14242 SELPLG PTHR17384:SF7 P-SELECTIN GLYCOPROTEIN LIGAND-1 P-SELECTIN GLYCOPROTEIN LIGAND 1 immune system development#GO:0002520;animal organ development#GO:0048513;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;localization of cell#GO:0051674;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;leukocyte cell-cell adhesion#GO:0007159;localization#GO:0051179;system development#GO:0048731;immune system process#GO:0002376;leukocyte migration#GO:0050900;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;cell migration#GO:0016477;locomotion#GO:0040011 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=20711|UniProtKB=Q96IU2 Q96IU2 ZBED3 PTHR35827:SF2 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 3 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=20499|UniProtKB=Q9H9P8 Q9H9P8 L2HGDH PTHR43104:SF2 L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 Ornithine degradation#P02758>Aminobutyraldehyde dehydrogenase#P03055 HUMAN|HGNC=1167|UniProtKB=Q9NQ35 Q9NQ35 NRIP3 PTHR12917:SF16 ASPARTYL PROTEASE DDI-RELATED NUCLEAR RECEPTOR-INTERACTING PROTEIN 3 aspartic protease#PC00053 HUMAN|HGNC=2591|UniProtKB=P15538 P15538 CYP11B1 PTHR24279:SF115 FAMILY NOT NAMED CYTOCHROME P450 11B1, MITOCHONDRIAL steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;response to peptide hormone#GO:0043434;alcohol biosynthetic process#GO:0046165;cholesterol metabolic process#GO:0008203;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular response to nitrogen compound#GO:1901699;steroid metabolic process#GO:0008202;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;response to peptide#GO:1901652;secondary alcohol metabolic process#GO:1902652;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;organic hydroxy compound metabolic process#GO:1901615;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;hormone biosynthetic process#GO:0042446;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;regulation of hormone levels#GO:0010817;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;small molecule biosynthetic process#GO:0044283;steroid biosynthetic process#GO:0006694;small molecule metabolic process#GO:0044281 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=18407|UniProtKB=Q9BSE5 Q9BSE5 AGMAT PTHR11358:SF26 ARGINASE/AGMATINASE AGMATINASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 hydrolase#PC00121 HUMAN|HGNC=26560|UniProtKB=Q96M63 Q96M63 CCDC114 PTHR21694:SF35 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 114 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;vesicle targeting#GO:0006903;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=12386|UniProtKB=Q9Y5U2 Q9Y5U2 TSSC4 PTHR13445:SF3 TUMOR SUPPRESSING SUBTRANSFERABLE CANDIDATE 4 TSSC4 PROTEIN TSSC4 HUMAN|Ensembl=ENSG00000283434|UniProtKB=A0A1B0GTH6 A0A1B0GTH6 CSNKA2IP PTHR35825:SF2 CASEIN KINASE II SUBUNIT ALPHA PRIME-INTERACTING PROTEIN CASEIN KINASE II SUBUNIT ALPHA'-INTERACTING PROTEIN HUMAN|HGNC=4878|UniProtKB=P06865 P06865 HEXA PTHR22600:SF39 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE SUBUNIT ALPHA glycosidase#PC00110 HUMAN|HGNC=33716|UniProtKB=Q6UXP7 Q6UXP7 FAM151B PTHR21184:SF3 MENORIN (DENDRITIC BRANCHING PROTEIN) PROTEIN FAM151B HUMAN|HGNC=9886|UniProtKB=P29375 P29375 KDM5A PTHR10694:SF17 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5A demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=16867|UniProtKB=O75150 O75150 RNF40 PTHR23163:SF4 RING FINGER PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE BRE1B HUMAN|HGNC=9451|UniProtKB=P04070 P04070 PROC PTHR24278:SF0 COAGULATION FACTOR VITAMIN K-DEPENDENT PROTEIN C extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>PC#P00426;Blood coagulation#P00011>APC#P00423 HUMAN|HGNC=24236|UniProtKB=Q8IX12 Q8IX12 CCAR1 PTHR14304:SF14 CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor transcription coactivator activity#GO:0030374;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=15593|UniProtKB=Q9UHA2 Q9UHA2 SS18L2 PTHR23107:SF21 SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN CALCIUM-RESPONSIVE TRANSACTIVATOR-RELATED positive regulation of gene expression#GO:0010628;regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;dendrite development#GO:0016358;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;aromatic compound biosynthetic process#GO:0019438;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of dendrite morphogenesis#GO:0048814;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;positive regulation of cell projection organization#GO:0031346;positive regulation of RNA biosynthetic process#GO:1902680;regulation of anatomical structure morphogenesis#GO:0022603;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;positive regulation of neuron differentiation#GO:0045666;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;dendrite morphogenesis#GO:0048813;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=13921|UniProtKB=O95870 O95870 ABHD16A PTHR12277:SF54 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLSERINE LIPASE ABHD16A hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;acylglycerol lipase activity#GO:0047372;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;acylglycerol catabolic process#GO:0046464;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=5002|UniProtKB=Q9P0W2 Q9P0W2 HMG20B PTHR46040:SF2 HIGH MOBILITY GROUP PROTEIN 2 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1-RELATED regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=13714|UniProtKB=Q9NP86 Q9NP86 CABP5 PTHR45917:SF3 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 5 HUMAN|HGNC=25845|UniProtKB=Q86UY6 Q86UY6 NAA40 PTHR20531:SF1 FAMILY NOT NAMED N-ALPHA-ACETYLTRANSFERASE 40 HUMAN|HGNC=16917|UniProtKB=Q15345 Q15345 LRRC41 PTHR15354:SF1 MUF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 41 HUMAN|HGNC=16833|UniProtKB=O14544 O14544 SOCS6 PTHR10155:SF28 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 6 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phosphorylation#GO:0016310;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 HUMAN|HGNC=452|UniProtKB=Q9NP70 Q9NP70 AMBN PTHR14115:SF0 AMELOBLASTIN AMELOBLASTIN HUMAN|HGNC=6024|UniProtKB=P16871 P16871 IL7R PTHR23037:SF27 CYTOKINE RECEPTOR INTERLEUKIN-7 RECEPTOR SUBUNIT ALPHA transmembrane signal receptor#PC00197 HUMAN|HGNC=12153|UniProtKB=A0A075B6T8 A0A075B6T8 TRAV9-1 PTHR23267:SF445 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 9-1 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=3235|UniProtKB=Q8IUX8 Q8IUX8 EGFL6 PTHR24050:SF24 PA14 DOMAIN-CONTAINING PROTEIN EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 6 HUMAN|HGNC=24300|UniProtKB=Q96N19 Q96N19 GPR137 PTHR15146:SF5 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137 regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of intracellular signal transduction#GO:1902531;tissue remodeling#GO:0048771;osteoclast differentiation#GO:0030316;regulation of biological process#GO:0050789;bone remodeling#GO:0046849;regulation of biological quality#GO:0065008;regulation of signal transduction#GO:0009966;regulation of tissue remodeling#GO:0034103;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;TOR signaling#GO:0031929;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;immune system development#GO:0002520;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;multicellular organismal homeostasis#GO:0048871;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of bone remodeling#GO:0046850;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;system development#GO:0048731;regulation of hemopoiesis#GO:1903706;tissue homeostasis#GO:0001894;positive regulation of TOR signaling#GO:0032008;bone resorption#GO:0045453;hemopoiesis#GO:0030097;catabolic process#GO:0009056;regulation of immune system process#GO:0002682;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;myeloid cell differentiation#GO:0030099;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;TORC1 signaling#GO:0038202;regulation of autophagy#GO:0010506;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of developmental process#GO:0050793;regulation of bone resorption#GO:0045124;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=26811|UniProtKB=Q8N8N0 Q8N8N0 RNF152 PTHR25464:SF1 TRIPARTITE MOTIF-CONTAINING PROTEIN 2-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF152 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=4798|UniProtKB=Q14520 Q14520 HABP2 PTHR24264:SF40 TRYPSIN-RELATED HYALURONAN-BINDING PROTEIN 2 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=15766|UniProtKB=Q9H2P0 Q9H2P0 ADNP PTHR15740:SF1 NEUROPROTECTIVE PEPTIDE-CONTAINING PROTEIN ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=28224|UniProtKB=Q9BRU9 Q9BRU9 UTP23 PTHR12416:SF3 UNCHARACTERIZED RRNA-PROCESSING PROTEIN UTP23 HOMOLOG HUMAN|HGNC=6960|UniProtKB=Q96EZ8 Q96EZ8 MCRS1 PTHR13233:SF0 MICROSPHERULE PROTEIN 1 MICROSPHERULE PROTEIN 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;H4 histone acetyltransferase activity#GO:0010485;N-acyltransferase activity#GO:0016410 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=24251|UniProtKB=Q9Y3A6 Q9Y3A6 TMED5 PTHR22811:SF41 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 5 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=13736|UniProtKB=Q9BZL1 Q9BZL1 UBL5 PTHR13042:SF3 UBIQUITIN-LIKE PROTEIN 5 UBIQUITIN-LIKE PROTEIN 5 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=2645|UniProtKB=P78329 P78329 CYP4F2 PTHR24291:SF158 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497 long-chain fatty acid metabolic process#GO:0001676;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid derivative metabolic process#GO:1901568;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 oxygenase#PC00177 HUMAN|HGNC=26646|UniProtKB=Q8NAF0 Q8NAF0 ZNF579 PTHR24383:SF14 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 579 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13200|UniProtKB=Q15942 Q15942 ZYX PTHR24212:SF1 ZYXIN/TRIP6 ZYXIN response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;transforming growth factor beta receptor signaling pathway#GO:0007179;cellular process#GO:0009987;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;anchoring junction#GO:0070161;cell junction#GO:0030054;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=3503|UniProtKB=Q92817 Q92817 EVPL PTHR23169:SF7 ENVOPLAKIN ENVOPLAKIN-RELATED cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;wound healing#GO:0042060;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intracellular#GO:0005622;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 intermediate filament binding protein#PC00130 HUMAN|HGNC=20729|UniProtKB=Q6X9E4 Q6X9E4 FBXW12 PTHR44019:SF17 WD REPEAT-CONTAINING PROTEIN 55 F-BOX/WD REPEAT-CONTAINING PROTEIN 12 HUMAN|HGNC=16158|UniProtKB=Q9BR10 Q9BR10 SPATA25 PTHR36857:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 25 SPERMATOGENESIS-ASSOCIATED PROTEIN 25 developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism process#GO:0051704;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609 HUMAN|HGNC=21157|UniProtKB=Q6ZYL4 Q6ZYL4 GTF2H5 PTHR28580:SF1 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5 DNA repair#GO:0006281;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;nucleotide-excision repair#GO:0006289;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;phosphorylation of RNA polymerase II C-terminal domain#GO:0070816;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675 general transcription factor#PC00259 HUMAN|HGNC=7045|UniProtKB=Q10469 Q10469 MGAT2 PTHR12871:SF0 BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE II ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=6146|UniProtKB=Q13349 Q13349 ITGAD PTHR23220:SF118 INTEGRIN ALPHA INTEGRIN ALPHA-D integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=28784|UniProtKB=Q96MD7 Q96MD7 C9orf85 PTHR22876:SF5 ZGC:101016 ZGC:101016 HUMAN|HGNC=2156|UniProtKB=Q99439 Q99439 CNN2 PTHR18959:SF47 CALPONIN/TRANSGELIN CALPONIN-2 non-motor actin binding protein#PC00165 HUMAN|HGNC=6532|UniProtKB=Q86U70 Q86U70 LDB1 PTHR10378:SF7 LIM DOMAIN-BINDING PROTEIN LIM DOMAIN-BINDING PROTEIN 1 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;activating transcription factor binding#GO:0033613;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Gonadotropin-releasing hormone receptor pathway#P06664>CLIM2#P06736 HUMAN|HGNC=25571|UniProtKB=Q9NVG8 Q9NVG8 TBC1D13 PTHR22957:SF27 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 13 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 Apoptosis signaling pathway#P00006>endoG#P00279 HUMAN|HGNC=24779|UniProtKB=Q8NDZ2 Q8NDZ2 SIMC1 PTHR23187:SF3 FLJ44216 PROTEIN-RELATED SUMO-INTERACTING MOTIF-CONTAINING PROTEIN 1 HUMAN|HGNC=26385|UniProtKB=Q8N769 Q8N769 C14orf178 PTHR12138:SF112 PRIMATE-EXPANDED PROTEIN FAMILY CHROMOSOME 14 OPEN READING FRAME 178 HUMAN|HGNC=29400|UniProtKB=Q96PX6 Q96PX6 CCDC85A PTHR13546:SF13 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85A HUMAN|HGNC=42951|UniProtKB=F2Z333 F2Z333 FNDC10 PTHR39233:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 10 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 10 HUMAN|HGNC=4846|UniProtKB=Q9UL51 Q9UL51 HCN2 PTHR45689:SF11 I[[H]] CHANNEL, ISOFORM E POTASSIUM/SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 2 ion channel#PC00133 HUMAN|HGNC=8994|UniProtKB=Q99755 Q99755 PIP5K1A PTHR23086:SF54 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 ALPHA kinase#PC00137 HUMAN|HGNC=26220|UniProtKB=Q9H611 Q9H611 PIF1 PTHR23274:SF11 DNA HELICASE-RELATED ATP-DEPENDENT DNA HELICASE PIF1 DNA helicase#PC00011 HUMAN|HGNC=10536|UniProtKB=Q9UL12 Q9UL12 SARDH PTHR13847:SF200 SARCOSINE DEHYDROGENASE-RELATED SARCOSINE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 HUMAN|HGNC=33265|UniProtKB=Q6ZRF7 Q6ZRF7 ZNF818P PTHR23226:SF74 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 500-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=8477|UniProtKB=Q15620 Q15620 OR8B8 PTHR48018:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=27452|UniProtKB=Q4G0X4 Q4G0X4 KCTD21 PTHR14499:SF57 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD21 enzyme binding#GO:0019899;histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 scaffold/adaptor protein#PC00226 HUMAN|HGNC=12665|UniProtKB=P18206 P18206 VCL PTHR46180:SF1 VINCULIN VINCULIN Gonadotropin-releasing hormone receptor pathway#P06664>Vinculin#P06771;Integrin signalling pathway#P00034>Vinculin#P00937 HUMAN|HGNC=6107|UniProtKB=P52945 P52945 PDX1 PTHR45664:SF12 PROTEIN ZERKNUELLT 1-RELATED PANCREAS/DUODENUM HOMEOBOX PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24350|UniProtKB=Q9H2F9 Q9H2F9 CCDC68 PTHR23171:SF3 GDOWN1 COILED-COIL DOMAIN-CONTAINING PROTEIN 68 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 HUMAN|HGNC=25133|UniProtKB=Q96GW9 Q96GW9 MARS2 PTHR43326:SF1 METHIONYL-TRNA SYNTHETASE METHIONINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=24759|UniProtKB=Q6ZUI0 Q6ZUI0 TPRG1 PTHR31108:SF6 TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN TUMOR PROTEIN P63-REGULATED GENE 1 PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=30617|UniProtKB=Q8TE02 Q8TE02 ELP5 PTHR15641:SF1 ELONGATOR COMPLEX PROTEIN 5 ELONGATOR COMPLEX PROTEIN 5 HUMAN|HGNC=24543|UniProtKB=Q52LR7 Q52LR7 EPC2 PTHR14898:SF4 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB HOMOLOG 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=11491|UniProtKB=P43405 P43405 SYK PTHR24418:SF231 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SYK immune response-regulating signaling pathway#GO:0002764;organelle localization#GO:0051640;activation of immune response#GO:0002253;organelle membrane fusion#GO:0090174;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;positive regulation of lymphocyte activation#GO:0051251;regulation of biological process#GO:0050789;secretion#GO:0046903;immune response-activating signal transduction#GO:0002757;B cell activation#GO:0042113;establishment of organelle localization#GO:0051656;leukocyte activation#GO:0045321;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;cell activation involved in immune response#GO:0002263;cell activation#GO:0001775;cellular component organization or biogenesis#GO:0071840;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;positive regulation of secretion by cell#GO:1903532;export from cell#GO:0140352;signal transduction#GO:0007165;platelet activation#GO:0030168;biological adhesion#GO:0022610;hematopoietic or lymphoid organ development#GO:0048534;positive regulation of T cell proliferation#GO:0042102;regulation of multicellular organismal development#GO:2000026;leukocyte cell-cell adhesion#GO:0007159;cell differentiation#GO:0030154;system development#GO:0048731;T cell proliferation#GO:0042098;vesicle organization#GO:0016050;regulation of immune system process#GO:0002682;immune effector process#GO:0002252;signaling#GO:0023052;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;hemostasis#GO:0007599;regulation of T cell proliferation#GO:0042129;regulation of response to wounding#GO:1903034;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;lymphocyte differentiation#GO:0030098;membrane fusion#GO:0061025;regulation of mononuclear cell proliferation#GO:0032944;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;blood coagulation#GO:0007596;positive regulation of cell adhesion#GO:0045785;antigen receptor-mediated signaling pathway#GO:0050851;cellular localization#GO:0051641;regulation of cell-cell adhesion#GO:0022407;membrane organization#GO:0061024;regulation of coagulation#GO:0050818;homotypic cell-cell adhesion#GO:0034109;regulation of secretion by cell#GO:1903530;B cell receptor signaling pathway#GO:0050853;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;regulation of vesicle-mediated transport#GO:0060627;positive regulation of leukocyte activation#GO:0002696;regulated exocytosis#GO:0045055;regulation of cell activation#GO:0050865;lysosome localization#GO:0032418;positive regulation of immune response#GO:0050778;regulation of wound healing#GO:0061041;regulation of biological quality#GO:0065008;positive regulation of exocytosis#GO:0045921;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;mononuclear cell proliferation#GO:0032943;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;immune system development#GO:0002520;positive regulation of secretion#GO:0051047;positive regulation of transport#GO:0051050;regulation of body fluid levels#GO:0050878;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;response to stress#GO:0006950;response to wounding#GO:0009611;leukocyte activation involved in immune response#GO:0002366;exocytosis#GO:0006887;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of cell activation#GO:0050867;positive regulation of multicellular organismal process#GO:0051240;vesicle fusion#GO:0006906;animal organ development#GO:0048513;cell adhesion mediated by integrin#GO:0033627;transport#GO:0006810;developmental process#GO:0032502;wound healing#GO:0042060;regulation of cell differentiation#GO:0045595;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;regulation of transport#GO:0051049;regulation of hemopoiesis#GO:1903706;platelet aggregation#GO:0070527;positive regulation of leukocyte cell-cell adhesion#GO:1903039;positive regulation of leukocyte mediated immunity#GO:0002705;hemopoiesis#GO:0030097;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;regulation of response to external stimulus#GO:0032101;lymphocyte activation#GO:0046649;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;leukocyte mediated immunity#GO:0002443;regulation of response to stress#GO:0080134;positive regulation of developmental process#GO:0051094;coagulation#GO:0050817;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;establishment of localization in cell#GO:0051649;regulation of leukocyte proliferation#GO:0070663;positive regulation of cell-cell adhesion#GO:0022409 B cell activation#P00010>Syk#P00382 HUMAN|HGNC=44440|UniProtKB=C9JPN9 C9JPN9 USP17L12 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=15549|UniProtKB=Q96KS9 Q96KS9 FAM167A PTHR32289:SF3 PROTEIN FAM167A PROTEIN FAM167A HUMAN|HGNC=29636|UniProtKB=Q8NEH6 Q8NEH6 MNS1 PTHR19265:SF0 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1 structural protein#PC00211 HUMAN|HGNC=26300|UniProtKB=Q17RF5 Q17RF5 ODAPH PTHR40376:SF1 ODONTOGENESIS ASSOCIATED PHOSPHOPROTEIN ODONTOGENESIS ASSOCIATED PHOSPHOPROTEIN biomineralization#GO:0110148;regulation of multicellular organismal process#GO:0051239;odontogenesis of dentin-containing tooth#GO:0042475;regulation of anatomical structure morphogenesis#GO:0022603;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of multicellular organismal development#GO:2000026;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of developmental process#GO:0051094;tissue development#GO:0009888;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;biomineral tissue development#GO:0031214;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 HUMAN|HGNC=1493|UniProtKB=P49589 P49589 CARS1 PTHR10890:SF3 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;ligase activity#GO:0016874;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a tRNA#GO:0140101;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=19195|UniProtKB=Q6H8Q1 Q6H8Q1 ABLIM2 PTHR24213:SF6 ACTIN-BINDING LIM PROTEIN ACTIN-BINDING LIM PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;cellular component organization#GO:0016043;plasma membrane bounded cell projection assembly#GO:0120031;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=11922|UniProtKB=P26842 P26842 CD27 PTHR47496:SF1 CD27 CD27 ANTIGEN regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=3189|UniProtKB=P68104 P68104 EEF1A1 PTHR23115:SF222 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 1-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111 cellular macromolecule biosynthetic process#GO:0034645;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation factor#PC00223 HUMAN|HGNC=3705|UniProtKB=O43427 O43427 FIBP PTHR13223:SF2 ACIDIC FIBROBLAST GROWTH FACTOR INTRACELLULAR BINDING PROTEIN ACIDIC FIBROBLAST GROWTH FACTOR INTRACELLULAR-BINDING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=30291|UniProtKB=Q9UN86 Q9UN86 G3BP2 PTHR10693:SF10 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=27647|UniProtKB=P0DPA3 P0DPA3 SNHG28 PTHR45166:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 8 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 8 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=30376|UniProtKB=Q8N114 Q8N114 SHISA5 PTHR31395:SF14 SHISA PROTEIN SHISA-5 scaffold/adaptor protein#PC00226 HUMAN|HGNC=4124|UniProtKB=Q10471 Q10471 GALNT2 PTHR11675:SF49 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=11763|UniProtKB=P02786 P02786 TFRC PTHR10404:SF26 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE TRANSFERRIN RECEPTOR PROTEIN 1 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;cation transport#GO:0006812;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular iron ion homeostasis#GO:0006879;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;iron ion homeostasis#GO:0055072;biological regulation#GO:0065007;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;metal ion homeostasis#GO:0055065 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=1953|UniProtKB=P08173 P08173 CHRM4 PTHR24247:SF180 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M4 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;organic cyclic compound binding#GO:0097159;acetylcholine receptor activity#GO:0015464;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;acetylcholine binding#GO:0042166;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;negative regulation of intracellular signal transduction#GO:1902532;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;negative regulation of catalytic activity#GO:0043086;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935;negative regulation of molecular function#GO:0044092 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>mAChR2/4#P01077;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=6556|UniProtKB=O95202 O95202 LETM1 PTHR14009:SF8 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN MITOCHONDRIAL PROTON/CALCIUM EXCHANGER PROTEIN cellular chemical homeostasis#GO:0055082;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;metal ion homeostasis#GO:0055065;cellular ion homeostasis#GO:0006873 secondary carrier transporter#PC00258 HUMAN|HGNC=10839|UniProtKB=P04278 P04278 SHBG PTHR24040:SF3 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN SEX HORMONE-BINDING GLOBULIN lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496 HUMAN|HGNC=20071|UniProtKB=Q53GS9 Q53GS9 USP39 PTHR21646:SF16 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE U4/U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2 cysteine protease#PC00081 HUMAN|HGNC=26200|UniProtKB=Q9H668 Q9H668 STN1 PTHR13989:SF16 REPLICATION PROTEIN A-RELATED CST COMPLEX SUBUNIT STN1 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 pre-replicative complex#GO:0036387;intracellular membrane-bounded organelle#GO:0043231;epsilon DNA polymerase complex#GO:0008622;replisome#GO:0030894;MCM complex#GO:0042555;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;chromosomal region#GO:0098687;replication fork#GO:0005657;membrane-enclosed lumen#GO:0031974;origin recognition complex#GO:0000808;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;DNA replication preinitiation complex#GO:0031261;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;CMG complex#GO:0071162;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;chromosome, telomeric region#GO:0000781;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 DNA replication#P00017>RPA#P00537 HUMAN|HGNC=7782|UniProtKB=Q16236 Q16236 NFE2L2 PTHR24411:SF3 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;response to oxidative stress#GO:0006979;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular response to chemical stress#GO:0062197;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to oxidative stress#GO:0034599;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=2445|UniProtKB=P47710 P47710 CSN1S1 PTHR10240:SF0 ALPHA-S1-CASEIN ALPHA-S1-CASEIN response to organic substance#GO:0010033;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to organic cyclic compound#GO:0014070;response to hormone#GO:0009725;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;response to lipid#GO:0033993;response to steroid hormone#GO:0048545;response to estradiol#GO:0032355 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 storage protein#PC00210 HUMAN|HGNC=30021|UniProtKB=Q9BYK8 Q9BYK8 HELZ2 PTHR10887:SF504 DNA2/NAM7 HELICASE FAMILY HELICASE WITH ZINC FINGER DOMAIN 2 HUMAN|HGNC=1116|UniProtKB=P35613 P35613 BSG PTHR10075:SF12 BASIGIN RELATED BASIGIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=19877|UniProtKB=Q8IXK2 Q8IXK2 GALNT12 PTHR11675:SF18 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 12 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=19214|UniProtKB=Q8TBC3 Q8TBC3 SHKBP1 PTHR15859:SF5 SETA BINDING PROTEIN 1 SH3KBP1-BINDING PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=467|UniProtKB=Q9Y4X0 Q9Y4X0 AMMECR1 PTHR13016:SF2 AMMECR1 HOMOLOG AMME SYNDROME CANDIDATE GENE 1 PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=10425|UniProtKB=P22090 P22090 RPS4Y1 PTHR11581:SF8 30S/40S RIBOSOMAL PROTEIN S4 40S RIBOSOMAL PROTEIN S4, Y ISOFORM 1 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|Ensembl=ENSG00000283740|UniProtKB=A0A1W2PQ09 A0A1W2PQ09 TAF11L11 PTHR13218:SF15 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TAF11-LIKE PROTEIN ENSP00000332601-RELATED transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=26685|UniProtKB=Q8N9Z2 Q8N9Z2 CCDC71L PTHR14484:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 71 COILED-COIL DOMAIN-CONTAINING PROTEIN 71L HUMAN|HGNC=23460|UniProtKB=Q8WWB3 Q8WWB3 DYDC1 PTHR23356:SF4 DPY30-RELATED DPY30 DOMAIN-CONTAINING PROTEIN 1 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;histone methylation#GO:0016571;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein alkylation#GO:0008213;protein methylation#GO:0006479;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;histone H3-K4 methylation#GO:0051568;cellular protein metabolic process#GO:0044267;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;chromatin silencing at telomere#GO:0006348;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;histone lysine methylation#GO:0034968;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=16928|UniProtKB=Q9BYR3 Q9BYR3 KRTAP4-4 PTHR23262:SF201 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-4 HUMAN|HGNC=17990|UniProtKB=Q96PB7 Q96PB7 OLFM3 PTHR23192:SF36 OLFACTOMEDIN-RELATED NOELIN-3 structural protein#PC00211 HUMAN|HGNC=26971|UniProtKB=Q6UXT9 Q6UXT9 ABHD15 PTHR10794:SF39 ABHYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD15 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;acylglycerol lipase activity#GO:0047372;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 serine protease#PC00203 HUMAN|HGNC=605|UniProtKB=Q9Y235 Q9Y235 APOBEC2 PTHR13857:SF4 MRNA EDITING ENZYME C-U-EDITING ENZYME APOBEC-2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;demethylation#GO:0070988;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=18750|UniProtKB=Q8WYP3 Q8WYP3 RIN2 PTHR23101:SF51 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR 2 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=28043|UniProtKB=O75541 O75541 ZNF821 PTHR24404:SF1 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 821 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=12144|UniProtKB=A0A075B6T7 A0A075B6T7 TRAV6 PTHR19433:SF121 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 6 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=19656|UniProtKB=Q7RTM1 Q7RTM1 OTOP1 PTHR21522:SF19 PROTON CHANNEL OTOP PROTON CHANNEL OTOP1 transporter#PC00227 HUMAN|HGNC=28129|UniProtKB=Q6UWU2 Q6UWU2 GLB1L PTHR23421:SF50 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE-1-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 galactosidase#PC00104 HUMAN|HGNC=32260|UniProtKB=A8MX19 A8MX19 FAM90A12P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=28503|UniProtKB=Q8N755 Q8N755 SLC66A3 PTHR12226:SF3 MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED SOLUTE CARRIER FAMILY 66 MEMBER 3 HUMAN|HGNC=6913|UniProtKB=P61244 P61244 MAX PTHR10328:SF3 PROTEIN MAX MYC-ASSOCIATED FACTOR X PROTEIN MAX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 Oxidative stress response#P00046>Max#P01133 HUMAN|HGNC=15322|UniProtKB=Q8NGQ1 Q8NGQ1 OR9G4 PTHR48018:SF129 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9G4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=25544|UniProtKB=Q9HCI7 Q9HCI7 MSL2 PTHR16048:SF3 MSL2-RELATED E3 UBIQUITIN-PROTEIN LIGASE MSL2 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;histone H4 acetylation#GO:0043967;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;peptidyl-lysine modification#GO:0018205;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;histone modification#GO:0016570;cellular component organization#GO:0016043;protein acylation#GO:0043543;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;organelle organization#GO:0006996;histone H4-K16 acetylation#GO:0043984;chromatin organization#GO:0006325;protein acetylation#GO:0006473;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=14572|UniProtKB=Q9H310 Q9H310 RHBG PTHR11730:SF42 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE B monovalent inorganic cation transmembrane transporter activity#GO:0015077;inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=9035|UniProtKB=P47712 P47712 PLA2G4A PTHR10728:SF13 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 hydrolase activity, acting on ester bonds#GO:0016788;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;phospholipid binding#GO:0005543;carboxylic ester hydrolase activity#GO:0052689;cation binding#GO:0043169;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;hydrolase activity#GO:0016787;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 phospholipase#PC00186 Oxidative stress response#P00046>cPLA2#P01134;Endothelin signaling pathway#P00019>cPLA2#P00583;Angiogenesis#P00005>PLA2#P00227;CCKR signaling map#P06959>PLA2#P07086;VEGF signaling pathway#P00056>cPLA2#P01409;Angiogenesis#P00005>cPLA2#P00251;Gonadotropin-releasing hormone receptor pathway#P06664>PLA2#P06738;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLA2#P00855 HUMAN|HGNC=14180|UniProtKB=Q13087 Q13087 PDIA2 PTHR18929:SF93 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A2 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;cellular process#GO:0009987;cellular response to stress#GO:0033554;protein folding#GO:0006457 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=12422|UniProtKB=Q9NNX1 Q9NNX1 TUFT1 PTHR23171:SF4 GDOWN1 TUFTELIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;sarcomere#GO:0030017;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;contractile fiber#GO:0043292;organelle#GO:0043226;myofibril#GO:0030016;intracellular organelle#GO:0043229;I band#GO:0031674 HUMAN|HGNC=7076|UniProtKB=Q16674 Q16674 MIA PTHR47312:SF1 MELANOMA-DERIVED GROWTH REGULATORY PROTEIN MELANOMA-DERIVED GROWTH REGULATORY PROTEIN cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 HUMAN|HGNC=236|UniProtKB=O95622 O95622 ADCY5 PTHR45627:SF7 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 5 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of adenylate cyclase activity#GO:0045761;cyclic nucleotide metabolic process#GO:0009187;purine nucleotide biosynthetic process#GO:0006164;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;negative regulation of signaling#GO:0023057;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cAMP-mediated signaling#GO:0019933;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;carbohydrate derivative metabolic process#GO:1901135;second-messenger-mediated signaling#GO:0019932;organophosphate biosynthetic process#GO:0090407;regulation of cyclase activity#GO:0031279;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;purine ribonucleotide biosynthetic process#GO:0009152;negative regulation of molecular function#GO:0044092;nucleobase-containing small molecule metabolic process#GO:0055086;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AC#P00841;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 HUMAN|Ensembl=ENSG00000273865|UniProtKB=A0A0G2JPF8 A0A0G2JPF8 HNRNPCL4 PTHR13968:SF30 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN C-LIKE 3-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=28382|UniProtKB=Q8NEP9 Q8NEP9 ZNF555 PTHR24381:SF51 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 555 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21587|UniProtKB=Q7Z5A9 Q7Z5A9 TAFA1 PTHR31770:SF2 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-1 receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cell division#GO:0051301;neurogenesis#GO:0022008;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of cell population proliferation#GO:0042127;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of multicellular organismal development#GO:2000026;cell population proliferation#GO:0008283;nervous system development#GO:0007399;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell development#GO:0048468;cell differentiation#GO:0030154;system development#GO:0048731;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;stem cell differentiation#GO:0048863;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=2933|UniProtKB=Q09013 Q09013 DMPK PTHR24356:SF392 SERINE/THREONINE-PROTEIN KINASE MYOTONIN-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=20083|UniProtKB=Q86TM3 Q86TM3 DDX53 PTHR47958:SF126 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX53-RELATED catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 HUMAN|HGNC=16637|UniProtKB=Q9BUP3 Q9BUP3 HTATIP2 PTHR14097:SF7 OXIDOREDUCTASE HTATIP2 OXIDOREDUCTASE HTATIP2 oxidoreductase#PC00176 HUMAN|HGNC=1784|UniProtKB=P38936 P38936 CDKN1A PTHR46778:SF1 CYCLIN-DEPENDENT KINASE INHIBITOR 1-RELATED CYCLIN-DEPENDENT KINASE INHIBITOR 1 kinase inhibitor#PC00139 p53 pathway#P00059>P21#P04631;p53 pathway feedback loops 2#P04398>P21#G04712;p53 pathway feedback loops 2#P04398>p21#P04667;Interleukin signaling pathway#P00036>p21CIP1#P00993;p53 pathway#P00059>p21#G01580 HUMAN|HGNC=2209|UniProtKB=P20908 P20908 COL5A1 PTHR24023:SF387 COLLAGEN ALPHA COLLAGEN ALPHA-1(V) CHAIN carbohydrate derivative binding#GO:0097367;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;heparin binding#GO:0008201;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;enzyme linked receptor protein signaling pathway#GO:0007167;collagen fibril organization#GO:0030199;biological adhesion#GO:0022610;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;extracellular structure organization#GO:0043062;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;extracellular region#GO:0005576;basement membrane#GO:0005604;collagen trimer#GO:0005581;supramolecular polymer#GO:0099081;extracellular space#GO:0005615;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=20854|UniProtKB=Q9H0W7 Q9H0W7 THAP2 PTHR47696:SF1 THAP DOMAIN-CONTAINING PROTEIN 2 THAP DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=32538|UniProtKB=Q58FF6 Q58FF6 HSP90AB4P PTHR11528:SF78 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-BETA 2-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of biological quality#GO:0065008;response to heat#GO:0009408;protein folding#GO:0006457;cellular response to heat#GO:0034605;biological regulation#GO:0065007;regulation of protein stability#GO:0031647;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;cellular process#GO:0009987;protein stabilization#GO:0050821 cytoplasm#GO:0005737;cell surface#GO:0009986;perinuclear region of cytoplasm#GO:0048471;intracellular#GO:0005622;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Hsp90 family chaperone#PC00028 HUMAN|HGNC=9205|UniProtKB=Q15165 Q15165 PON2 PTHR11799:SF17 PARAOXONASE SERUM PARAOXONASE/ARYLESTERASE 2 HUMAN|HGNC=3483|UniProtKB=Q16134 Q16134 ETFDH PTHR10617:SF107 ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL 4 iron, 4 sulfur cluster binding#GO:0051539;metal cluster binding#GO:0051540;electron transfer activity#GO:0009055;iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;electron transport chain#GO:0022900;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 oxidoreductase#PC00176 HUMAN|HGNC=28973|UniProtKB=Q14165 Q14165 MLEC PTHR13460:SF0 UNCHARACTERIZED MALECTIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=4103|UniProtKB=Q13070 Q13070 GAGE6 PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=21244|UniProtKB=Q8NC56 Q8NC56 LEMD2 PTHR13428:SF8 INNER NUCLEAR MEMBRANE PROTEIN MAN1 LEM DOMAIN CONTAINING PROTEIN LEM DOMAIN-CONTAINING PROTEIN 2 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;membrane organization#GO:0061024;response to growth factor#GO:0070848;negative regulation of cellular response to growth factor stimulus#GO:0090288;regulation of signaling#GO:0023051;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;BMP signaling pathway#GO:0030509;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;organelle organization#GO:0006996;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;negative regulation of signal transduction#GO:0009968;nuclear envelope organization#GO:0006998 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=21773|UniProtKB=Q5W064 Q5W064 LIPJ PTHR11005:SF11 LYSOSOMAL ACID LIPASE-RELATED LIPASE MEMBER J membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 lipase#PC00143 HUMAN|HGNC=15559|UniProtKB=Q8WYQ3 Q8WYQ3 CHCHD10 PTHR13523:SF4 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 10, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18279|UniProtKB=Q9NYH9 Q9NYH9 UTP6 PTHR23271:SF3 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 HUMAN|HGNC=24465|UniProtKB=Q9UL52 Q9UL52 TMPRSS11E PTHR24253:SF84 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11E serine protease#PC00203 HUMAN|HGNC=12537|UniProtKB=P35504 P35504 UGT1A5 PTHR48050:SF12 STEROL 3-BETA-GLUCOSYLTRANSFERASE UDP-GLUCURONOSYLTRANSFERASE 1A3-RELATED glycosyltransferase#PC00111 Nicotine degradation#P05914>UGT1A4#P05982 HUMAN|HGNC=30799|UniProtKB=Q9BZD6 Q9BZD6 PRRG4 PTHR24251:SF15 OVOCHYMASE-RELATED TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 4 serine protease#PC00203 HUMAN|HGNC=10021|UniProtKB=Q9Y572 Q9Y572 RIPK3 PTHR23257:SF723 SERINE-THREONINE PROTEIN KINASE RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=6510|UniProtKB=P16949 P16949 STMN1 PTHR10104:SF5 STATHMIN STATHMIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cellular protein complex disassembly#GO:0043624;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 Cytoskeletal regulation by Rho GTPase#P00016>Op18/stathmin#P00513 HUMAN|HGNC=18586|UniProtKB=Q2TAA8 Q2TAA8 TSNAXIP1 PTHR16306:SF0 TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1 TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=12958|UniProtKB=P17021 P17021 ZNF17 PTHR24377:SF930 IP01015P-RELATED ZINC FINGER PROTEIN 17 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10068|UniProtKB=Q99942 Q99942 RNF5 PTHR12313:SF4 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF5 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 cellular response to misfolded protein#GO:0071218;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;response to topologically incorrect protein#GO:0035966;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=18514|UniProtKB=Q8N0X7 Q8N0X7 SPART PTHR21068:SF20 SPARTIN SPARTIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=23595|UniProtKB=Q5THJ4 Q5THJ4 VPS13D PTHR16166:SF93 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13D cellular localization#GO:0051641;establishment of protein localization to vacuole#GO:0072666;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;cellular protein localization#GO:0034613;protein localization to vacuole#GO:0072665;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;protein localization to Golgi apparatus#GO:0034067;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365 cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898 membrane traffic protein#PC00150 HUMAN|HGNC=17269|UniProtKB=Q96PC2 Q96PC2 IP6K3 PTHR12400:SF40 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;organic hydroxy compound biosynthetic process#GO:1901617;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 HUMAN|HGNC=24205|UniProtKB=Q96KX2 Q96KX2 CAPZA3 PTHR10653:SF6 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cortical actin cytoskeleton#GO:0030864;actin cortical patch#GO:0030479;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=19753|UniProtKB=Q9H2X8 Q9H2X8 IFI27L2 PTHR16932:SF35 INTERFERON ALPHA-INDUCIBLE PROTEIN 27 INTERFERON ALPHA-INDUCIBLE PROTEIN 27-LIKE PROTEIN 2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=2379|UniProtKB=O75718 O75718 CRTAP PTHR13986:SF3 PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT CARTILAGE-ASSOCIATED PROTEIN collagen binding#GO:0005518;protein-containing complex binding#GO:0044877;binding#GO:0005488 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;collagen fibril organization#GO:0030199;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;nitrogen compound metabolic process#GO:0006807;supramolecular fiber organization#GO:0097435;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=15803|UniProtKB=Q9NU02 Q9NU02 ANKEF1 PTHR24127:SF1 ANKYRIN REPEAT AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=4705|UniProtKB=P15421 P15421 GYPE PTHR13813:SF4 GLYCOPHORIN GLYCOPHORIN-E intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=25687|UniProtKB=Q9BRP4 Q9BRP4 PAAF1 PTHR42968:SF30 WD REPEAT-CONTAINING PROTEASOMAL ATPASE-ASSOCIATED FACTOR 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=10012|UniProtKB=P08100 P08100 RHO PTHR24240:SF15 OPSIN RHODOPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to abiotic stimulus#GO:0071214;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin#P00747 HUMAN|HGNC=2736|UniProtKB=Q96FC9 Q96FC9 DDX11 PTHR11472:SF41 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER ATP-DEPENDENT DNA HELICASE DDX11-RELATED pyrophosphatase activity#GO:0016462;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;DNA conformation change#GO:0071103;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA duplex unwinding#GO:0032508;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059;DNA geometric change#GO:0032392 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA helicase#PC00011 HUMAN|HGNC=1663|UniProtKB=P16671 P16671 CD36 PTHR11923:SF12 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 PLATELET GLYCOPROTEIN 4 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=6859|UniProtKB=O43318 O43318 MAP3K7 PTHR46716:SF1 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 non-receptor serine/threonine protein kinase#PC00167 Interleukin signaling pathway#P00036>MEK#P00984;p38 MAPK pathway#P05918>TAK1#P06037;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Toll receptor signaling pathway#P00054>TAK1#P01370;Gonadotropin-releasing hormone receptor pathway#P06664>TAK1#P06799;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MEK#P00864;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;TGF-beta signaling pathway#P00052>TAK#P01285 HUMAN|HGNC=289|UniProtKB=P25098 P25098 GRK2 PTHR24355:SF22 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE BETA-ADRENERGIC RECEPTOR KINASE 1 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GPRK#P00840;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK2#P05943;Parkinson disease#P00049>GRK#P01234 HUMAN|HGNC=12588|UniProtKB=P0C7P4 P0C7P4 UQCRFS1P1 PTHR10134:SF20 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=11535|UniProtKB=P21675 P21675 TAF1 PTHR13900:SF1 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1 molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription regulator activity#GO:0140110;RNA polymerase II general transcription initiation factor activity#GO:0016251;transcription factor binding#GO:0008134;binding#GO:0005488;TBP-class protein binding#GO:0017025 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=6308|UniProtKB=P23276 P23276 KEL PTHR11733:SF128 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED KELL BLOOD GROUP GLYCOPROTEIN metalloprotease#PC00153 HUMAN|HGNC=33179|UniProtKB=A6NMX2 A6NMX2 EIF4E1B PTHR11960:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 1B translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;RNA cap binding#GO:0000339 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 p38 MAPK pathway#P05918>eIF4E#P06024 HUMAN|HGNC=8168|UniProtKB=Q8NH80 Q8NH80 OR10D3 PTHR26453:SF221 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10D3-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=24164|UniProtKB=O94811 O94811 TPPP PTHR12932:SF18 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;positive regulation of protein polymerization#GO:0032273;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=13195|UniProtKB=O95229 O95229 ZWINT PTHR31504:SF1 ZW10 INTERACTOR ZWINT ZW10 INTERACTOR nuclear chromosome segregation#GO:0098813;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;mitotic cell cycle checkpoint#GO:0007093;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;nuclear division#GO:0000280;cell cycle process#GO:0022402;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;cell cycle checkpoint#GO:0000075;establishment of localization#GO:0051234;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;mitotic sister chromatid segregation#GO:0000070;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;chromosome, centromeric region#GO:0000775;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;plasma membrane region#GO:0098590;chromosomal region#GO:0098687;cell projection#GO:0042995;membrane-enclosed lumen#GO:0031974;somatodendritic compartment#GO:0036477;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;nuclear body#GO:0016604;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;plasma membrane#GO:0005886 HUMAN|HGNC=4805|UniProtKB=Q16775 Q16775 HAGH PTHR11935:SF80 BETA LACTAMASE DOMAIN HYDROXYACYLGLUTATHIONE HYDROLASE, MITOCHONDRIAL HUMAN|HGNC=10608|UniProtKB=P47872 P47872 SCTR PTHR45620:SF13 PDF RECEPTOR-LIKE PROTEIN-RELATED SECRETIN RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|Gene_ORFName=UNQ785/PRO1604|UniProtKB=Q7Z4V5 Q7Z4V5 HDGFL2 PTHR12550:SF18 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR-RELATED PROTEIN 2 nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=23432|UniProtKB=Q9NXG0 Q9NXG0 CNTLN PTHR18957:SF0 CENTLEIN CENTLEIN cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=28992|UniProtKB=Q92628 Q92628 KIAA0232 PTHR17611:SF3 UNCHARACTERIZED HYPOTHETICAL PROTEIN LOC680039 HUMAN|HGNC=37472|UniProtKB=A0A494C1R9 A0A494C1R9 TSPY9P PTHR11875:SF12 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED PROTEIN 1-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=25575|UniProtKB=Q9NVF9 Q9NVF9 ETNK2 PTHR22603:SF94 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE 2 kinase#PC00137 HUMAN|HGNC=16521|UniProtKB=Q14964 Q14964 RAB39A PTHR47979:SF3 DRAB11-RELATED RAS-RELATED PROTEIN RAB-39A bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=5154|UniProtKB=P15428 P15428 HPGD PTHR44229:SF4 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] dehydrogenase#PC00092 HUMAN|HGNC=13248|UniProtKB=Q9BXU9 Q9BXU9 CALN1 PTHR46311:SF3 CALCIUM-BINDING PROTEIN 8-RELATED CALCIUM-BINDING PROTEIN 8 HUMAN|HGNC=29069|UniProtKB=A6NMS7 A6NMS7 LRRC37A PTHR23045:SF11 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=4565|UniProtKB=Q14449 Q14449 GRB14 PTHR11243:SF22 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of signal transduction#GO:0009966;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Grb14#P00197 HUMAN|HGNC=998|UniProtKB=P20749 P20749 BCL3 PTHR24118:SF51 POTE ANKYRIN DOMAIN B-CELL LYMPHOMA 3 PROTEIN membrane traffic protein#PC00150 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859 HUMAN|HGNC=9459|UniProtKB=Q92786 Q92786 PROX1 PTHR12198:SF6 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 PROSPERO HOMEOBOX PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=15899|UniProtKB=Q5TEU4 Q5TEU4 NDUFAF5 PTHR13090:SF1 UNCHARACTERIZED ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL HUMAN|HGNC=4127|UniProtKB=Q7Z7M9 Q7Z7M9 GALNT5 PTHR11675:SF126 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 5 glycosyltransferase#PC00111 HUMAN|HGNC=26775|UniProtKB=Q8IY95 Q8IY95 TMEM192 PTHR31592:SF1 TRANSMEMBRANE PROTEIN 192 TRANSMEMBRANE PROTEIN 192 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=37252|UniProtKB=A8MVX0 A8MVX0 ARHGEF33 PTHR46944:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 33 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 33 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=4866|UniProtKB=Q9BQS7 Q9BQS7 HEPH PTHR11709:SF221 MULTI-COPPER OXIDASE HEPHAESTIN ferroxidase activity#GO:0004322;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;cation transport#GO:0006812;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;localization#GO:0051179;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;establishment of localization#GO:0051234;iron ion homeostasis#GO:0055072;biological regulation#GO:0065007;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;metal ion homeostasis#GO:0055065 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175 HUMAN|HGNC=25788|UniProtKB=Q5T2E6 Q5T2E6 ARMH3 PTHR13608:SF3 UNCHARACTERIZED ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=14234|UniProtKB=Q96L73 Q96L73 NSD1 PTHR22884:SF312 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 SPECIFIC N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=19245|UniProtKB=Q96RF0 Q96RF0 SNX18 PTHR45827:SF4 SORTING NEXIN SORTING NEXIN-18 scaffold/adaptor protein#PC00226 HUMAN|HGNC=4283|UniProtKB=P08034 P08034 GJB1 PTHR11984:SF20 CONNEXIN GAP JUNCTION BETA-1 PROTEIN gap junction#PC00105 HUMAN|HGNC=23095|UniProtKB=Q8WUG5 Q8WUG5 SLC22A17 PTHR24064:SF216 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 17 secondary carrier transporter#PC00258 HUMAN|HGNC=27026|UniProtKB=Q569G3 Q569G3 C5orf47 PTHR38655:SF1 SIMILAR TO RIKEN CDNA 4930524B15 SIMILAR TO RIKEN CDNA 4930524B15 HUMAN|HGNC=37177|UniProtKB=A8MUK1 A8MUK1 USP17L5 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=20511|UniProtKB=Q9BTD3 Q9BTD3 TMEM121 PTHR31046:SF0 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 121 HUMAN|HGNC=1762|UniProtKB=P22223 P22223 CDH3 PTHR24027:SF319 CADHERIN-23 CADHERIN-3 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Alzheimer disease-presenilin pathway#P00004>E-cadherin transmembrane fragment#P00139;Cadherin signaling pathway#P00012>Cadherin#P00471;Alzheimer disease-presenilin pathway#P00004>E-cadherin intracellular fragment#P00168;Alzheimer disease-presenilin pathway#P00004>E-cadherin N-terminal fragment#P00165;Alzheimer disease-presenilin pathway#P00004>E-cadherin C-terminal fragment#P00117;Wnt signaling pathway#P00057>Cadherin#P01440;Alzheimer disease-presenilin pathway#P00004>E-cadherin#P00118 HUMAN|HGNC=11062|UniProtKB=O43246 O43246 SLC7A4 PTHR43243:SF89 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046 HUMAN|HGNC=12857|UniProtKB=Q9Y493 Q9Y493 ZAN PTHR11339:SF374 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED ZONADHESIN extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=20070|UniProtKB=Q3LFD5 Q3LFD5 USP41 PTHR24006:SF796 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBL CARBOXYL-TERMINAL HYDROLASE 18-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=19916|UniProtKB=Q5T7B8 Q5T7B8 KIF24 PTHR47971:SF8 KINESIN-RELATED PROTEIN 6 KINESIN-LIKE PROTEIN KIF24 microtubule binding motor protein#PC00156 HUMAN|HGNC=37275|UniProtKB=A4FU28 A4FU28 CTAGE9 PTHR23158:SF57 MELANOMA INHIBITORY ACTIVITY-RELATED CTAGE FAMILY MEMBER 15-RELATED endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=11471|UniProtKB=Q8IYB8 Q8IYB8 SUPV3L1 PTHR12131:SF1 ATP-DEPENDENT RNA AND DNA HELICASE ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL DNA metabolism protein#PC00009 HUMAN|HGNC=12833|UniProtKB=P13010 P13010 XRCC5 PTHR12604:SF4 KU AUTOANTIGEN DNA HELICASE X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;cellular response to abiotic stimulus#GO:0071214;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;response to ionizing radiation#GO:0010212;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;biological regulation#GO:0065007;cellular response to stress#GO:0033554;cellular response to environmental stimulus#GO:0104004;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;nuclear chromosome, telomeric region#GO:0000784;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 DNA helicase#PC00011 HUMAN|HGNC=16343|UniProtKB=A0A0G2JN01 A0A0G2JN01 KIR3DP1 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=11365|UniProtKB=Q14765 Q14765 STAT4 PTHR11801:SF19 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;defense response#GO:0006952;organic substance metabolic process#GO:0071704;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;response to peptide hormone#GO:0043434;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;receptor signaling pathway via STAT#GO:0097696;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>STAT#P01173;JAK/STAT signaling pathway#P00038>STAT#P01027;Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561 HUMAN|HGNC=15874|UniProtKB=Q9Y4P9 Q9Y4P9 SPEF1 PTHR12509:SF16 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERM FLAGELLAR PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=1577|UniProtKB=P78396 P78396 CCNA1 PTHR10177:SF254 CYCLINS CYCLIN-A1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin A#P04666 HUMAN|HGNC=24293|UniProtKB=Q70JA7 Q70JA7 CHSY3 PTHR12369:SF40 CHONDROITIN SYNTHASE CHONDROITIN SULFATE SYNTHASE 3 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;chondroitin sulfate metabolic process#GO:0030204;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;proteoglycan metabolic process#GO:0006029;chondroitin sulfate proteoglycan metabolic process#GO:0050654;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;glycosaminoglycan biosynthetic process#GO:0006024;small molecule metabolic process#GO:0044281 glycosyltransferase#PC00111 HUMAN|HGNC=30292|UniProtKB=Q13283 Q13283 G3BP1 PTHR10693:SF21 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=18710|UniProtKB=Q8N0V4 Q8N0V4 LGI2 PTHR24367:SF21 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 2 HUMAN|HGNC=20866|UniProtKB=Q9BXY4 Q9BXY4 RSPO3 PTHR46987:SF1 FAMILY NOT NAMED R-SPONDIN-3 HUMAN|HGNC=32166|UniProtKB=A6NFQ7 A6NFQ7 DPRX PTHR45793:SF15 HOMEOBOX PROTEIN DIVERGENT PAIRED-RELATED HOMEOBOX cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=30034|UniProtKB=Q6ZUJ8 Q6ZUJ8 PIK3AP1 PTHR16267:SF12 BANK1/PIK3AP1 FAMILY MEMBER PHOSPHOINOSITIDE 3-KINASE ADAPTER PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=10706|UniProtKB=O94855 O94855 SEC24D PTHR13803:SF6 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24D cation binding#GO:0043169;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;Golgi vesicle budding#GO:0048194;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=16285|UniProtKB=Q9UPQ4 Q9UPQ4 TRIM35 PTHR24103:SF611 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 35 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=17423|UniProtKB=Q9NRB3 Q9NRB3 CHST12 PTHR12137:SF4 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 12 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=14807|UniProtKB=Q8NGN2 Q8NGN2 OR10S1 PTHR26453:SF205 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10S1 transmembrane signal receptor#PC00197 HUMAN|HGNC=195|UniProtKB=P78536 P78536 ADAM17 PTHR45702:SF6 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 17 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cell communication#GO:0007154;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>TACE#P00092;Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-presenilin pathway#P00004>TACE#P00147 HUMAN|HGNC=6342|UniProtKB=P10721 P10721 KIT PTHR24416:SF46 TYROSINE-PROTEIN KINASE RECEPTOR MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 regulation of MAPK cascade#GO:0043408;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;regulation of localization#GO:0032879;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of cell migration#GO:0030334;positive regulation of receptor signaling pathway via STAT#GO:1904894;B cell activation#GO:0042113;regulation of MAP kinase activity#GO:0043405;cellular protein metabolic process#GO:0044267;leukocyte activation#GO:0045321;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell activation#GO:0001775;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;hematopoietic or lymphoid organ development#GO:0048534;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of cell motility#GO:2000147;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;immune system process#GO:0002376;lymphocyte differentiation#GO:0030098;positive regulation of protein metabolic process#GO:0051247;receptor signaling pathway via STAT#GO:0097696;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cell surface receptor signaling pathway#GO:0007166;positive regulation of kinase activity#GO:0033674;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component movement#GO:0051272;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;positive regulation of locomotion#GO:0040017;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;movement of cell or subcellular component#GO:0006928;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;animal organ development#GO:0048513;positive regulation of MAP kinase activity#GO:0043406;developmental process#GO:0032502;regulation of receptor signaling pathway via STAT#GO:1904892;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;receptor signaling pathway via JAK-STAT#GO:0007259;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;lymphocyte activation#GO:0046649;multicellular organism development#GO:0007275;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=1402|UniProtKB=Q08289 Q08289 CACNB2 PTHR11824:SF9 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;synaptic signaling#GO:0099536;divalent inorganic cation transport#GO:0072511;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;signaling#GO:0023052;cell-cell signaling#GO:0007267;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;regulation of calcium ion transport#GO:0051924;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;neuromuscular junction development#GO:0007528;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of ion transport#GO:0043269 membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096 HUMAN|HGNC=24369|UniProtKB=Q9Y536 Q9Y536 PPIAL4A PTHR11071:SF450 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A-LIKE 4A membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=37161|UniProtKB=P0CJ71 P0CJ71 MTRNR2L4 PTHR33895:SF5 HUMANIN-LIKE 4 HUMANIN-LIKE 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=10696|UniProtKB=O00471 O00471 EXOC5 PTHR12100:SF4 SEC10 EXOCYST COMPLEX COMPONENT 5 vesicle fusion#GO:0006906;vesicle-mediated transport to the plasma membrane#GO:0098876;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;exocytic process#GO:0140029;Golgi to plasma membrane transport#GO:0006893;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;vesicle organization#GO:0016050;export from cell#GO:0140352;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=18442|UniProtKB=Q0VAF6 Q0VAF6 SYCN PTHR17503:SF0 SYNCOLLIN SYNCOLLIN bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=9992|UniProtKB=O43665 O43665 RGS10 PTHR45945:SF4 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G-PROTEIN SIGNALING 10 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=29917|UniProtKB=Q8TC05 Q8TC05 MDM1 PTHR32078:SF1 NUCLEAR PROTEIN MDM1 NUCLEAR PROTEIN MDM1 HUMAN|HGNC=9206|UniProtKB=Q15166 Q15166 PON3 PTHR11799:SF14 PARAOXONASE SERUM PARAOXONASE/LACTONASE 3 HUMAN|HGNC=9802|UniProtKB=P15153 P15153 RAC2 PTHR24072:SF169 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;membrane organization#GO:0061024;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;phagocytosis#GO:0006909;regulation of organelle organization#GO:0033043;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;apoptotic cell clearance#GO:0043277;locomotion#GO:0040011;taxis#GO:0042330;establishment or maintenance of cell polarity#GO:0007163;neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;transport#GO:0006810;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;supramolecular fiber organization#GO:0097435;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;neuron differentiation#GO:0030182;vesicle organization#GO:0016050;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;vesicle budding from membrane#GO:0006900;regulation of developmental process#GO:0050793;motor neuron axon guidance#GO:0008045;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 small GTPase#PC00208 T cell activation#P00053>rac#P01324;Huntington disease#P00029>Rac#P00775;p38 MAPK pathway#P05918>Rac#P06021;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Axon guidance mediated by semaphorins#P00007>Rac#P00340;VEGF signaling pathway#P00056>Rac#P01421;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by netrin#P00009>Rac#P00366;B cell activation#P00010>Rac#P00385;Integrin signalling pathway#P00034>Rac#P00927;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;FGF signaling pathway#P00021>Rac#P00645 HUMAN|HGNC=30264|UniProtKB=Q8NCN5 Q8NCN5 PDPR PTHR13847:SF193 SARCOSINE DEHYDROGENASE-RELATED PYRUVATE DEHYDROGENASE PHOSPHATASE REGULATORY SUBUNIT, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=26723|UniProtKB=Q8N9M1 Q8N9M1 C19orf47 PTHR21359:SF1 UNCHARACTERIZED DUF5577 DOMAIN-CONTAINING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=28501|UniProtKB=Q96BV0 Q96BV0 ZNF775 PTHR24377:SF614 IP01015P-RELATED ZINC FINGER PROTEIN 775 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=29802|UniProtKB=Q96BX8 Q96BX8 MOB3A PTHR22599:SF10 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 3A kinase activator#PC00138 HUMAN|HGNC=30449|UniProtKB=Q7Z6K3 Q7Z6K3 PTAR1 PTHR11129:SF3 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein prenylation#GO:0018342;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 acyltransferase#PC00042 HUMAN|HGNC=30453|UniProtKB=Q96ET8 Q96ET8 TVP23C PTHR13019:SF23 UNCHARACTERIZED GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG C macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=14495|UniProtKB=Q9Y399 Q9Y399 MRPS2 PTHR12534:SF0 30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR 28S RIBOSOMAL PROTEIN S2, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribosomal protein#PC00202 HUMAN|HGNC=3061|UniProtKB=P23919 P23919 DTYMK PTHR10344:SF1 THYMIDYLATE KINASE THYMIDYLATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;pyrimidine nucleotide biosynthetic process#GO:0006221;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotide kinase#PC00172 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916 HUMAN|HGNC=7556|UniProtKB=P12525 P12525 MYCLP1 PTHR45851:SF5 MYC PROTO-ONCOGENE PROTEIN L-MYC-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 HUMAN|HGNC=15683|UniProtKB=Q9C0J1 Q9C0J1 B3GNT4 PTHR11214:SF148 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 4 glycosyltransferase#PC00111 HUMAN|HGNC=23625|UniProtKB=Q8N2Y8 Q8N2Y8 RUSC2 PTHR15591:SF14 RUN AND SH3 DOMAIN CONTAINING IPORIN cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=16519|UniProtKB=Q9BZG1 Q9BZG1 RAB34 PTHR47977:SF8 LD21953P-RELATED RAS-RELATED PROTEIN RAB-34 lysosome organization#GO:0007040;vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284 HUMAN|HGNC=10063|UniProtKB=Q9BYJ4 Q9BYJ4 TRIM34 PTHR24103:SF647 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 34 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;protein homodimerization activity#GO:0042803;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;identical protein binding#GO:0042802;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;kinase binding#GO:0019900 regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;aromatic compound biosynthetic process#GO:0019438;positive regulation of autophagy#GO:0010508;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=34297|UniProtKB=A8MYJ7 A8MYJ7 TTC34 PTHR44874:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 34 TETRATRICOPEPTIDE REPEAT PROTEIN 34 HUMAN|HGNC=25599|UniProtKB=Q3KP66 Q3KP66 INAVA PTHR16093:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 120 FAMILY MEMBER INNATE IMMUNITY ACTIVATOR PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cell-cell junction organization#GO:0045216;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=25433|UniProtKB=Q8N468 Q8N468 MFSD4A PTHR23121:SF10 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 4A transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 transporter#PC00227 HUMAN|HGNC=4516|UniProtKB=Q8IZP9 Q8IZP9 ADGRG2 PTHR12011:SF264 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=2234|UniProtKB=O14579 O14579 COPE PTHR10805:SF0 COATOMER SUBUNIT EPSILON COATOMER SUBUNIT EPSILON localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;COPI vesicle coat#GO:0030126;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=6602|UniProtKB=O75019 O75019 LILRA1 PTHR11738:SF165 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 1-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=6902|UniProtKB=O00187 O00187 MASP2 PTHR24255:SF10 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED MANNAN-BINDING LECTIN SERINE PROTEASE 2 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=26925|UniProtKB=Q6PCB6 Q6PCB6 ABHD17C PTHR12277:SF55 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17C hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;macromolecule deacylation#GO:0098732;protein deacylation#GO:0035601;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;lipoprotein metabolic process#GO:0042157;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=23534|UniProtKB=A6NHL2 A6NHL2 TUBAL3 PTHR11588:SF278 TUBULIN TUBULIN ALPHA CHAIN-LIKE 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 HUMAN|HGNC=1692|UniProtKB=P08962 P08962 CD63 PTHR19282:SF471 TETRASPANIN CD63 ANTIGEN response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=19225|UniProtKB=Q8WVX3 Q8WVX3 C4orf3 PTHR37367:SF1 CHROMOSOME 4 OPEN READING FRAME 3 CHROMOSOME 4 OPEN READING FRAME 3 HUMAN|HGNC=2535|UniProtKB=P09668 P09668 CTSH PTHR12411:SF642 CYSTEINE PROTEASE FAMILY C1-RELATED PRO-CATHEPSIN H cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=3481|UniProtKB=P13804 P13804 ETFA PTHR43153:SF1 ELECTRON TRANSFER FLAVOPROTEIN ALPHA ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL oxidoreductase#PC00176 HUMAN|HGNC=7046|UniProtKB=Q09327 Q09327 MGAT3 PTHR12224:SF0 BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 glycosyltransferase#PC00111 HUMAN|HGNC=7783|UniProtKB=Q9Y4A8 Q9Y4A8 NFE2L3 PTHR24411:SF8 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=20332|UniProtKB=Q9H1J1 Q9H1J1 UPF3A PTHR13112:SF2 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN REGULATOR OF NONSENSE TRANSCRIPTS 3A sequence-specific DNA binding#GO:0043565;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=8266|UniProtKB=Q8NH16 Q8NH16 OR2L2 PTHR26453:SF645 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2L2 transmembrane signal receptor#PC00197 HUMAN|HGNC=706|UniProtKB=O15145 O15145 ARPC3 PTHR12391:SF9 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 HUMAN|HGNC=10991|UniProtKB=P05141 P05141 SLC25A5 PTHR45635:SF3 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP/ATP TRANSLOCASE 2 carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organophosphate ester transmembrane transporter activity#GO:0015605;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;purine nucleotide transmembrane transporter activity#GO:0015216;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ATP transmembrane transporter activity#GO:0005347;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide transmembrane transporter activity#GO:0015215;active ion transmembrane transporter activity#GO:0022853 transfer/carrier protein#PC00219 HUMAN|HGNC=29344|UniProtKB=Q9UFD9 Q9UFD9 RIMBP3 PTHR14234:SF21 RIM BINDING PROTEIN-RELATED RIMS-BINDING PROTEIN 3A-RELATED germ cell development#GO:0007281;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;spermatid differentiation#GO:0048515;cellular process#GO:0009987;multi-organism process#GO:0051704;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;synaptic signaling#GO:0099536;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;neuromuscular synaptic transmission#GO:0007274;multi-organism reproductive process#GO:0044703;cell-cell signaling#GO:0007267;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=24154|UniProtKB=Q8N8U9 Q8N8U9 BMPER PTHR11339:SF272 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED BMP-BINDING ENDOTHELIAL REGULATOR PROTEIN regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;regulation of developmental process#GO:0050793;tube morphogenesis#GO:0035239;regulation of vasculature development#GO:1901342;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;vasculature development#GO:0001944;multicellular organismal process#GO:0032501 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=20653|UniProtKB=Q8IVB4 Q8IVB4 SLC9A9 PTHR10110:SF61 SODIUM/HYDROGEN EXCHANGER SODIUM/HYDROGEN EXCHANGER 9 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=8877|UniProtKB=P08237 P08237 PFKM PTHR13697:SF13 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, MUSCLE TYPE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;carbon-carbon lyase activity#GO:0016830;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;fructose-bisphosphate aldolase activity#GO:0004332;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;carbohydrate binding#GO:0030246;isomerase activity#GO:0016853;kinase activity#GO:0016301;oxidoreductase activity#GO:0016491;cation binding#GO:0043169;carbon-oxygen lyase activity#GO:0016835;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;hydro-lyase activity#GO:0016836;intramolecular transferase activity#GO:0016866;organic cyclic compound binding#GO:0097159;identical protein binding#GO:0042802;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glucose metabolic process#GO:0006006;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;hexose metabolic process#GO:0019318;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphofructokinase-1#P00672 HUMAN|HGNC=10498|UniProtKB=P05109 P05109 S100A8 PTHR11639:SF5 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A8 calmodulin-related#PC00061 HUMAN|HGNC=31696|UniProtKB=Q6ZSG1 Q6ZSG1 RNF165 PTHR22937:SF173 E3 UBIQUITIN-PROTEIN LIGASE RNF165 E3 UBIQUITIN-PROTEIN LIGASE RNF165 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=7908|UniProtKB=O60500 O60500 NPHS1 PTHR11640:SF136 NEPHRIN NEPHRIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=44155|UniProtKB=Q2WGJ8 Q2WGJ8 TMEM249 PTHR35442:SF1 TRANSMEMBRANE PROTEIN 249 TRANSMEMBRANE PROTEIN 249 HUMAN|HGNC=19233|UniProtKB=Q495W5 Q495W5 FUT11 PTHR11929:SF198 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE 11 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111 HUMAN|HGNC=9787|UniProtKB=O95235 O95235 KIF20A PTHR24115:SF352 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF20A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=11393|UniProtKB=O14965 O14965 AURKA PTHR24350:SF5 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE A transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cell division#GO:0051301;mitotic spindle organization#GO:0007052;membrane fission#GO:0090148;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;regulation of cell division#GO:0051302;mitotic cell cycle process#GO:1903047;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;spindle organization#GO:0007051;cytokinesis#GO:0000910;regulation of cytokinesis#GO:0032465 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome#GO:0000794;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;centrosome#GO:0005813;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;spindle#GO:0005819;microtubule#GO:0005874;membrane-enclosed lumen#GO:0031974;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;organelle lumen#GO:0043233;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome, centromeric region#GO:0000780;supramolecular fiber#GO:0099512;centriole#GO:0005814;polymeric cytoskeletal fiber#GO:0099513;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=9366|UniProtKB=P02810 P02810 PRH1 PTHR23203:SF19 PROLINE-RICH PROTEIN SALIVARY ACIDIC PROLINE-RICH PHOSPHOPROTEIN 1/2 antimicrobial response protein#PC00051 HUMAN|HGNC=1929|UniProtKB=P10645 P10645 CHGA PTHR10583:SF1 CHROMOGRANIN CHROMOGRANIN-A response to external biotic stimulus#GO:0043207;organic hydroxy compound transport#GO:0015850;regulation of adenylate cyclase activity#GO:0045761;system process#GO:0003008;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;protein secretion#GO:0009306;regulation of localization#GO:0032879;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;hormone secretion#GO:0046879;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;secretion#GO:0046903;regulation of secretion#GO:0051046;regulation of signal transduction#GO:0009966;insulin secretion#GO:0030073;intracellular signal transduction#GO:0035556;hormone transport#GO:0009914;defense response#GO:0006952;negative regulation of cell communication#GO:0010648;regulation of protein localization#GO:0032880;regulation of peptide hormone secretion#GO:0090276;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of protein secretion#GO:0050708;interspecies interaction between organisms#GO:0044419;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;negative regulation of transport#GO:0051051;peptide transport#GO:0015833;circulatory system process#GO:0003013;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;establishment of protein localization to extracellular region#GO:0035592;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;protein transport#GO:0015031;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;protein localization to extracellular region#GO:0071692;cAMP-mediated signaling#GO:0019933;regulation of establishment of protein localization#GO:0070201;export from cell#GO:0140352;regulation of peptide transport#GO:0090087;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;second-messenger-mediated signaling#GO:0019932;macromolecule localization#GO:0033036;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;transport#GO:0006810;regulation of insulin secretion#GO:0050796;peptide secretion#GO:0002790;regulation of catalytic activity#GO:0050790;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;response to bacterium#GO:0009617;peptide hormone secretion#GO:0030072;regulation of hormone secretion#GO:0046883;signal release#GO:0023061;regulation of protein transport#GO:0051223;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;secretion by cell#GO:0032940;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological regulation#GO:0065007;muscle system process#GO:0003012;heart process#GO:0003015;cyclic-nucleotide-mediated signaling#GO:0019935 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 CCKR signaling map#P06959>CHGA#G07271;CCKR signaling map#P06959>CHGA#G06978 HUMAN|HGNC=11473|UniProtKB=Q13503 Q13503 MED21 PTHR13381:SF1 RNA POLYMERASE II HOLOENZYME COMPONENT SRB7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=10820|UniProtKB=O60880 O60880 SH2D1A PTHR46051:SF6 SH2 DOMAIN-CONTAINING PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 1A HUMAN|HGNC=10969|UniProtKB=O76082 O76082 SLC22A5 PTHR24064:SF283 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 5 secondary carrier transporter#PC00258 HUMAN|HGNC=913|UniProtKB=P20160 P20160 AZU1 PTHR24271:SF10 KALLIKREIN-RELATED AZUROCIDIN intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=33717|UniProtKB=Q5VZV1 Q5VZV1 METTL21C PTHR14614:SF13 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE METHYLTRANSFERASE METTL21C N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;nitrogen compound metabolic process#GO:0006807;peptidyl-lysine trimethylation#GO:0018023;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=13242|UniProtKB=Q9HCP6 Q9HCP6 HHATL PTHR13285:SF19 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE HHAT-LIKE PROTEIN transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824 negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;lipoprotein metabolic process#GO:0042157;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=28966|UniProtKB=Q14135 Q14135 VGLL4 PTHR17604:SF1 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 transcription cofactor#PC00217 HUMAN|HGNC=8725|UniProtKB=Q16822 Q16822 PCK2 PTHR11561:SF11 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE [GTP], MITOCHONDRIAL cation binding#GO:0043169;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;lyase activity#GO:0016829;ion binding#GO:0043167 liver development#GO:0001889;alcohol biosynthetic process#GO:0046165;lipid catabolic process#GO:0016042;response to extracellular stimulus#GO:0009991;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;neutral lipid metabolic process#GO:0006638;cellular response to hormone stimulus#GO:0032870;regulation of biological quality#GO:0065008;triglyceride biosynthetic process#GO:0019432;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;alcohol metabolic process#GO:0006066;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;response to stress#GO:0006950;cellular carbohydrate metabolic process#GO:0044262;cellular response to organonitrogen compound#GO:0071417;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;monosaccharide metabolic process#GO:0005996;lipid metabolic process#GO:0006629;response to organic cyclic compound#GO:0014070;response to insulin#GO:0032868;epithelium development#GO:0060429;response to peptide hormone#GO:0043434;cellular response to steroid hormone stimulus#GO:0071383;animal organ development#GO:0048513;developmental process#GO:0032502;response to lipid#GO:0033993;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;cellular homeostasis#GO:0019725;cellular response to nitrogen compound#GO:1901699;cellular response to lipid#GO:0071396;system development#GO:0048731;cell differentiation#GO:0030154;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;cellular response to organic cyclic compound#GO:0071407;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;response to organic substance#GO:0010033;carbohydrate biosynthetic process#GO:0016051;cellular response to stimulus#GO:0051716;gland development#GO:0048732;triglyceride metabolic process#GO:0006641;cellular response to chemical stimulus#GO:0070887;glycerolipid biosynthetic process#GO:0045017;multicellular organism development#GO:0007275;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;response to nutrient levels#GO:0031667;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;epithelial cell differentiation#GO:0030855;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;tissue development#GO:0009888;glucose metabolic process#GO:0006006;fatty acid catabolic process#GO:0009062;cellular chemical homeostasis#GO:0055082;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;response to hormone#GO:0009725;response to chemical#GO:0042221;response to starvation#GO:0042594;biological regulation#GO:0065007;hexose metabolic process#GO:0019318;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;response to steroid hormone#GO:0048545 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 HUMAN|HGNC=29602|UniProtKB=Q86YL7 Q86YL7 PDPN PTHR47390:SF1 PODOPLANIN PODOPLANIN HUMAN|HGNC=23581|UniProtKB=Q5SRD1 Q5SRD1 TIMM23B PTHR15371:SF0 TIM23 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM23-RELATED protein transmembrane transporter activity#GO:0008320;amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 amino acid transporter#PC00046 HUMAN|HGNC=12391|UniProtKB=Q99614 Q99614 TTC1 PTHR46014:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 HUMAN|Ensembl=ENSG00000167524|UniProtKB=Q96LW2 Q96LW2 RSKR PTHR24355:SF1 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE-RELATED PROTEIN non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=33631|UniProtKB=Q5VY43 Q5VY43 PEAR1 PTHR24052:SF12 DELTA-RELATED PLATELET ENDOTHELIAL AGGREGATION RECEPTOR 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=23522|UniProtKB=Q5VUB5 Q5VUB5 FAM171A1 PTHR31626:SF1 FAMILY NOT NAMED PROTEIN FAM171A1 HUMAN|HGNC=10826|UniProtKB=Q9P0V3 Q9P0V3 SH3BP4 PTHR15603:SF3 SH3 DOMAIN-CONTAINING PROTEIN SH3 DOMAIN-BINDING PROTEIN 4 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=26558|UniProtKB=Q96M11 Q96M11 HYLS1 PTHR34174:SF1 HYDROLETHALUS SYNDROME PROTEIN 1 HYDROLETHALUS SYNDROME PROTEIN 1 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=25128|UniProtKB=Q96HP4 Q96HP4 OXNAD1 PTHR46505:SF1 OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176 HUMAN|HGNC=31454|UniProtKB=Q6A555 Q6A555 TXNDC8 PTHR10438:SF230 THIOREDOXIN THIOREDOXIN DOMAIN-CONTAINING PROTEIN 8 oxidoreductase#PC00176 HUMAN|HGNC=2954|UniProtKB=Q9UI46 Q9UI46 DNAI1 PTHR12442:SF11 DYNEIN INTERMEDIATE CHAIN DYNEIN INTERMEDIATE CHAIN 1, AXONEMAL dynein heavy chain binding#GO:0045504;protein binding#GO:0005515;binding#GO:0005488 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;vesicle targeting#GO:0006903;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=26487|UniProtKB=Q96DN2 Q96DN2 VWCE PTHR47333:SF1 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=18153|UniProtKB=O14836 O14836 TNFRSF13B PTHR15511:SF2 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 13B transmembrane signal receptor#PC00197 HUMAN|HGNC=21074|UniProtKB=Q9NU53 Q9NU53 GINM1 PTHR28549:SF1 GLYCOPROTEIN INTEGRAL MEMBRANE PROTEIN 1 GLYCOPROTEIN INTEGRAL MEMBRANE PROTEIN 1 HUMAN|HGNC=11920|UniProtKB=P25445 P25445 FAS PTHR46874:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;tumor necrosis factor binding#GO:0043120;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;cytokine binding#GO:0019955 neuron apoptotic process#GO:0051402;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;neuron death#GO:0070997;regulation of apoptotic signaling pathway#GO:2001233;positive regulation of proteolysis#GO:0045862;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cell communication#GO:0007154;programmed cell death#GO:0012501;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of programmed cell death#GO:0043068;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;positive regulation of apoptotic signaling pathway#GO:2001235;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of stress-activated protein kinase signaling cascade#GO:0070302;regulation of cell communication#GO:0010646;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;regulation of response to stress#GO:0080134;homeostatic process#GO:0042592;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;extrinsic apoptotic signaling pathway#GO:0097191;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell death#GO:0010942 membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane raft#GO:0045121;membrane#GO:0016020;side of membrane#GO:0098552;membrane region#GO:0098589;membrane microdomain#GO:0098857;whole membrane#GO:0098805;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 p53 pathway#P00059>FAS#G01571;Apoptosis signaling pathway#P00006>FAS#P00289;FAS signaling pathway#P00020>Fas#P00612 HUMAN|HGNC=26690|UniProtKB=Q8N960 Q8N960 CEP120 PTHR21574:SF0 UNCHARACTERIZED CENTROSOMAL PROTEIN OF 120 KDA regulation of microtubule-based process#GO:0032886;head development#GO:0060322;nuclear migration#GO:0007097;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;positive regulation of organelle organization#GO:0010638;animal organ development#GO:0048513;transport#GO:0006810;developmental process#GO:0032502;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;brain development#GO:0007420;centrosome duplication#GO:0051298;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell population proliferation#GO:0008283;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of cytoskeleton organization#GO:0051493;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;positive regulation of cell cycle process#GO:0090068;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;central nervous system development#GO:0007417;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of centrosome duplication#GO:0010824;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;forebrain development#GO:0030900;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;positive regulation of cytoskeleton organization#GO:0051495;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;nucleus localization#GO:0051647 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=9201|UniProtKB=P01189 P01189 POMC PTHR11416:SF7 PRO-OPIOMELANOCORTIN PRO-OPIOMELANOCORTIN Opioid proopiomelanocortin pathway#P05917>proopiomelanocortin#P06010;Opioid proopiomelanocortin pathway#P05917>ACTH#P06008;Opioid proopiomelanocortin pathway#P05917>alpha-MSH#P06007;Cortocotropin releasing factor receptor signaling pathway#P04380>ACTH#P04453;Cortocotropin releasing factor receptor signaling pathway#P04380>proopiomelanocortin#G04671;Opioid proopiomelanocortin pathway#P05917>beta-Endorphin#P06006;Cortocotropin releasing factor receptor signaling pathway#P04380>proopiomelanocortin#P04452;Cortocotropin releasing factor receptor signaling pathway#P04380>beta-endorphin#P04455 HUMAN|HGNC=19754|UniProtKB=Q96BM0 Q96BM0 IFI27L1 PTHR16932:SF2 INTERFERON ALPHA-INDUCIBLE PROTEIN 27 INTERFERON ALPHA-INDUCIBLE PROTEIN 27-LIKE PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26717|UniProtKB=Q96AQ9 Q96AQ9 FAM131C PTHR15736:SF2 PROTEIN FAM131B-RELATED PROTEIN FAM131C HUMAN|HGNC=8981|UniProtKB=Q92569 Q92569 PIK3R3 PTHR10155:SF2 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;regulation of catalytic activity#GO:0050790;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;regulation of molecular function#GO:0065009;cellular response to insulin stimulus#GO:0032869;phosphorylation#GO:0016310;signaling#GO:0023052;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;regulation of lipid metabolic process#GO:0019216;cellular lipid metabolic process#GO:0044255;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;phosphatidylinositol phosphorylation#GO:0046854;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 PDGF signaling pathway#P00047>PI3K#P01168;PI3 kinase pathway#P00048>p85#P01202;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;VEGF signaling pathway#P00056>PI3K#P01413;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 HUMAN|HGNC=6875|UniProtKB=O15264 O15264 MAPK13 PTHR24055:SF107 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 13 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Integrin signalling pathway#P00034>ERK#P00907;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;TGF-beta signaling pathway#P00052>P38#P01275;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>p38#P00562;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Ras Pathway#P04393>p38#P04558;B cell activation#P00010>p38#P00384;p38 MAPK pathway#P05918>p38delta#P06020;Oxidative stress response#P00046>p38#P01135;FGF signaling pathway#P00021>p38#P00644 HUMAN|HGNC=19173|UniProtKB=Q8TAZ6 Q8TAZ6 CMTM2 PTHR22776:SF15 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=9591|UniProtKB=Q13258 Q13258 PTGDR PTHR11866:SF14 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN D2 RECEPTOR signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;organic acid binding#GO:0043177;transmembrane signaling receptor activity#GO:0004888 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of intracellular signal transduction#GO:1902531;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=12762|UniProtKB=O76024 O76024 WFS1 PTHR13098:SF3 WOLFRAMIN WOLFRAMIN response to organic substance#GO:0010033;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;calcium ion homeostasis#GO:0055074;response to endoplasmic reticulum stress#GO:0034976;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to unfolded protein#GO:0006986;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;cellular response to stress#GO:0033554;metal ion homeostasis#GO:0055065;signaling#GO:0023052 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=29304|UniProtKB=Q2YD98 Q2YD98 UVSSA PTHR28670:SF1 UV-STIMULATED SCAFFOLD PROTEIN A UV-STIMULATED SCAFFOLD PROTEIN A basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;response to UV#GO:0009411;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694;intracellular#GO:0005622 HUMAN|HGNC=5233|UniProtKB=P0DMV9 P0DMV9 HSPA1B PTHR19375:SF223 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 1A-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524;ATPase activity#GO:0016887 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;chaperone-mediated protein folding#GO:0061077;cellular response to organic substance#GO:0071310;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;'de novo' protein folding#GO:0006458;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;COP9 signalosome#GO:0008180;vesicle#GO:0031982;intracellular organelle#GO:0043229 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 HUMAN|HGNC=25578|UniProtKB=Q86V59 Q86V59 PNMA8A PTHR23095:SF21 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 8A HUMAN|HGNC=17231|UniProtKB=Q9BYQ0 Q9BYQ0 KRTAP9-8 PTHR23262:SF210 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-3-RELATED HUMAN|HGNC=17205|UniProtKB=Q9HCN3 Q9HCN3 PGAP6 PTHR14319:SF7 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 POST-GPI ATTACHMENT TO PROTEINS FACTOR 6-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=3971|UniProtKB=P19883 P19883 FST PTHR10913:SF6 FOLLISTATIN-RELATED FOLLISTATIN protein-containing complex binding#GO:0044877;activin binding#GO:0048185;binding#GO:0005488 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#G06885;Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#P06835;Gonadotropin-releasing hormone receptor pathway#P06664>Follistatin#G06671 HUMAN|HGNC=25429|UniProtKB=Q8N3G9 Q8N3G9 TMEM130 PTHR11861:SF10 MELANOCYTE PROTEIN PMEL 17-RELATED TRANSMEMBRANE PROTEIN 130 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=34300|UniProtKB=A4D1F6 A4D1F6 LRRD1 PTHR45752:SF50 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25394|UniProtKB=Q7Z3H4 Q7Z3H4 SAMD7 PTHR12247:SF89 POLYCOMB GROUP PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 7 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=30042|UniProtKB=Q9H008 Q9H008 LHPP PTHR19288:SF44 4-NITROPHENYLPHOSPHATASE-RELATED PHOSPHOLYSINE PHOSPHOHISTIDINE INORGANIC PYROPHOSPHATE PHOSPHATASE pyrophosphatase activity#GO:0016462;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=26374|UniProtKB=Q5M9N0 Q5M9N0 CCDC158 PTHR47615:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 HUMAN|HGNC=18082|UniProtKB=Q9Y5S1 Q9Y5S1 TRPV2 PTHR10582:SF5 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 2 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;divalent metal ion transport#GO:0070838;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=20461|UniProtKB=Q9Y5B8 Q9Y5B8 NME7 PTHR43109:SF2 NUCLEOSIDE DIPHOSPHATE KINASE 7 NUCLEOSIDE DIPHOSPHATE KINASE 7 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 kinase#PC00137 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 HUMAN|HGNC=4853|UniProtKB=Q92769 Q92769 HDAC2 PTHR48252:SF17 HISTONE DEACETYLASE 2-RELATED HISTONE DEACETYLASE 2 Wnt signaling pathway#P00057>Histone deacetylase#P01472;p53 pathway#P00059>HDAC1#P04612 HUMAN|HGNC=4220|UniProtKB=P43026 P43026 GDF5 PTHR11848:SF44 TGF-BETA FAMILY GROWTH/DIFFERENTIATION FACTOR 5 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=23501|UniProtKB=O94933 O94933 SLITRK3 PTHR45773:SF6 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 3 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;generation of neurons#GO:0048699;cell part morphogenesis#GO:0032990 HUMAN|HGNC=24099|UniProtKB=Q8IUR5 Q8IUR5 TMTC1 PTHR44809:SF1 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC1 HUMAN|HGNC=24250|UniProtKB=Q96D46 Q96D46 NMD3 PTHR12746:SF2 NONSENSE-MEDIATED MRNA DECAY PROTEIN 3 60S RIBOSOMAL EXPORT PROTEIN NMD3 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;ribosome biogenesis#GO:0042254;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;peptide transport#GO:0015833;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;ribonucleoprotein complex biogenesis#GO:0022613;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4311|UniProtKB=P48506 P48506 GCLC PTHR11164:SF0 GLUTAMATE CYSTEINE LIGASE GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT ligase activity#GO:0016874;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ligase#PC00142 HUMAN|HGNC=29093|UniProtKB=O75152 O75152 ZC3H11A PTHR15725:SF2 ZN-FINGER, C-X8-C-X5-C-X3-H TYPE-CONTAINING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 11A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=21406|UniProtKB=Q5T160 Q5T160 RARS2 PTHR11956:SF11 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;mitochondrial translation#GO:0032543;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=30387|UniProtKB=Q7Z5L0 Q7Z5L0 VMO1 PTHR18841:SF2 VITELLINE MEMBRANE OUTER LAYER PROTEIN I-RELATED VITELLINE MEMBRANE OUTER LAYER PROTEIN 1 HOMOLOG HUMAN|HGNC=26843|UniProtKB=Q502W7 Q502W7 CCDC38 PTHR21683:SF7 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 38 HUMAN|HGNC=11218|UniProtKB=Q9NS26 Q9NS26 SPANXA2 PTHR23425:SF16 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME A-RELATED HUMAN|HGNC=22196|UniProtKB=O15069 O15069 NACAD PTHR21713:SF1 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NAC-ALPHA DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|Ensembl=ENSG00000180042|UniProtKB=A0A286YEU6 A0A286YEU6 ENSG00000180042 PTHR26451:SF196 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=15005|UniProtKB=Q8N628 Q8N628 OR2C3 PTHR26453:SF117 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2C3 transmembrane signal receptor#PC00197 HUMAN|HGNC=26689|UniProtKB=Q6ZN01 Q6ZN01 MAMSTR PTHR23251:SF1 LYSINE-RICH CEACAM1 CO-ISOLATED PROTEIN LYRIC PROTEIN MEF2-ACTIVATING MOTIF AND SAP DOMAIN-CONTAINING TRANSCRIPTIONAL REGULATOR transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;RNA polymerase II transcription factor binding#GO:0001085;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=7681|UniProtKB=P52849 P52849 NDST2 PTHR10605:SF53 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE/N-SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;heparan sulfate proteoglycan metabolic process#GO:0030201;proteoglycan biosynthetic process#GO:0030166;cellular carbohydrate metabolic process#GO:0044262;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;cellular polysaccharide biosynthetic process#GO:0033692;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=30727|UniProtKB=Q9UNN4 Q9UNN4 GTF2A1L PTHR12694:SF9 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TFIIA-ALPHA AND BETA-LIKE FACTOR nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 HUMAN|HGNC=18276|UniProtKB=P61619 P61619 SEC61A1 PTHR10906:SF19 SECY/SEC61-ALPHA FAMILY MEMBER PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 1 signal sequence binding#GO:0005048;transmembrane transporter activity#GO:0022857;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;amide transmembrane transporter activity#GO:0042887;protein transmembrane transporter activity#GO:0008320;protein-containing complex binding#GO:0044877;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;translation#GO:0006412;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;posttranslational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein localization to organelle#GO:0033365;cellular protein metabolic process#GO:0044267;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;amide biosynthetic process#GO:0043604;protein targeting to membrane#GO:0006612;peptide biosynthetic process#GO:0043043;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=26174|UniProtKB=Q6PK18 Q6PK18 OGFOD3 PTHR14650:SF1 PROLYL HYDROXYLASE-RELATED 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 3 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein modifying enzyme#PC00260 HUMAN|HGNC=28147|UniProtKB=Q8N9N8 Q8N9N8 EIF1AD PTHR21641:SF0 TRANSLATION INITIATION FACTOR-RELATED RNA-BINDING PROTEIN EIF1AD-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 translation initiation factor#PC00224 HUMAN|HGNC=15172|UniProtKB=Q8NGL9 Q8NGL9 OR4C16 PTHR48002:SF106 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C16 transmembrane signal receptor#PC00197 HUMAN|HGNC=19141|UniProtKB=Q6IQ55 Q6IQ55 TTBK2 PTHR11909:SF451 CASEIN KINASE-RELATED TAU-TUBULIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;cellular protein metabolic process#GO:0044267;establishment of organelle localization#GO:0051656;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;macromolecule metabolic process#GO:0043170;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;vesicle localization#GO:0051648;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;peptidyl-serine modification#GO:0018209;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=21158|UniProtKB=Q8IUD6 Q8IUD6 RNF135 PTHR25465:SF16 FAMILY NOT NAMED E3 UBIQUITIN-PROTEIN LIGASE RNF135 HUMAN|HGNC=9416|UniProtKB=Q13237 Q13237 PRKG2 PTHR24353:SF24 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE PROTEIN KINASE CGMP-DEPENDENT 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Endothelin signaling pathway#P00019>PKG#P00567 HUMAN|HGNC=15909|UniProtKB=Q9HCD5 Q9HCD5 NCOA5 PTHR23295:SF3 NUCLEAR RECEPTOR COACTIVATOR 5-RELATED NUCLEAR RECEPTOR COACTIVATOR 5 transcription cofactor#PC00217 HUMAN|HGNC=24771|UniProtKB=Q6ZUJ4 Q6ZUJ4 C3orf62 PTHR36680:SF1 HYPOTHETICAL LOC498675 HYPOTHETICAL LOC498675 HUMAN|HGNC=24786|UniProtKB=Q5TZF3 Q5TZF3 ANKRD45 PTHR24180:SF14 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 45 kinase inhibitor#PC00139 HUMAN|HGNC=30488|UniProtKB=Q6P9A2 Q6P9A2 GALNT18 PTHR11675:SF37 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 18 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=34520|UniProtKB=Q6ZS10 Q6ZS10 CLEC17A PTHR22802:SF240 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 17, MEMBER A membrane traffic protein#PC00150 HUMAN|HGNC=9100|UniProtKB=O75051 O75051 PLXNA2 PTHR22625:SF37 PLEXIN PLEXIN-A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of GTPase activity#GO:0043087;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of neuron differentiation#GO:0045664;negative regulation of cell adhesion#GO:0007162;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;positive regulation of neuron projection development#GO:0010976;locomotion#GO:0040011;taxis#GO:0042330;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of cell projection organization#GO:0031346;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;biological adhesion#GO:0022610;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of cell adhesion#GO:0030155;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;positive regulation of neuron differentiation#GO:0045666;cellular response to stimulus#GO:0051716;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;cell migration#GO:0016477 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=30540|UniProtKB=Q96G28 Q96G28 CFAP36 PTHR21532:SF0 PHOSPHODIESTERASE HL CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36 supramolecular complex#GO:0099080;axoneme#GO:0005930;ciliary base#GO:0097546;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;ciliary transition fiber#GO:0097539;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 phosphodiesterase#PC00185 HUMAN|HGNC=20125|UniProtKB=Q8IVF2 Q8IVF2 AHNAK2 PTHR23348:SF37 PERIAXIN/AHNAK PROTEIN AHNAK2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229 HUMAN|HGNC=30493|UniProtKB=Q8TF30 Q8TF30 WHAMM PTHR23330:SF6 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED WASP HOMOLOG-ASSOCIATED PROTEIN WITH ACTIN, MEMBRANES AND MICROTUBULES-RELATED Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;small GTPase binding#GO:0031267;GTP-Rho binding#GO:0017049;Rho GTPase binding#GO:0017048 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;transport#GO:0006810;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;negative regulation of cell cycle#GO:0045786;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cell cycle arrest#GO:0007050;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;cell cycle#GO:0007049;positive regulation of cytoskeleton organization#GO:0051495;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 HUMAN|HGNC=12385|UniProtKB=Q53GA4 Q53GA4 PHLDA2 PTHR15478:SF8 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 2 developmental process involved in reproduction#GO:0003006;reproductive system development#GO:0061458;system development#GO:0048731;reproduction#GO:0000003;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;reproductive structure development#GO:0048608 HUMAN|HGNC=25436|UniProtKB=Q8N3T6 Q8N3T6 TMEM132C PTHR13388:SF4 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 132C HUMAN|HGNC=2447|UniProtKB=P05814 P05814 CSN2 PTHR11500:SF0 BETA CASEIN BETA-CASEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 storage protein#PC00210 HUMAN|HGNC=4026|UniProtKB=P54710 P54710 FXYD2 PTHR14132:SF3 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of sodium ion transport#GO:0002028;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;sodium ion transport#GO:0006814;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;sodium ion transmembrane transport#GO:0035725 primary active transporter#PC00068 HUMAN|HGNC=17449|UniProtKB=Q9NYL5 Q9NYL5 CYP39A1 PTHR24304:SF2 CYTOCHROME P450 FAMILY 7 24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE oxygenase#PC00177 HUMAN|HGNC=23312|UniProtKB=Q7Z6W1 Q7Z6W1 TMCO2 PTHR38496:SF1 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=26285|UniProtKB=Q5SXH7 Q5SXH7 PLEKHS1 PTHR47014:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY S MEMBER 1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY S MEMBER 1 HUMAN|HGNC=5623|UniProtKB=A0A0B4J1V6 A0A0B4J1V6 IGHV3-73 PTHR23266:SF333 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-73 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=33848|UniProtKB=Q86WW8 Q86WW8 COA5 PTHR28627:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=8495|UniProtKB=Q9Y267 Q9Y267 SLC22A14 PTHR24064:SF48 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 14 secondary carrier transporter#PC00258 HUMAN|HGNC=22945|UniProtKB=P59045 P59045 NLRP11 PTHR45690:SF5 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 11 HUMAN|HGNC=21744|UniProtKB=Q9BZB8 Q9BZB8 CPEB1 PTHR12566:SF9 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 synapse#GO:0045202;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=15667|UniProtKB=P58546 P58546 MTPN PTHR24189:SF52 MYOTROPHIN MYOTROPHIN cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17381|UniProtKB=O14492 O14492 SH2B2 PTHR10872:SF4 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 2 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular response to stimulus#GO:0051716;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;activation of immune response#GO:0002253;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;immune system process#GO:0002376;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25735|UniProtKB=Q14D04 Q14D04 VEPH1 PTHR21630:SF10 VEPH-A/MELTED VENTRICULAR ZONE-EXPRESSED PH DOMAIN-CONTAINING PROTEIN HOMOLOG 1 lipid binding#GO:0008289;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=14866|UniProtKB=Q96QV1 Q96QV1 HHIP PTHR19328:SF27 HEDGEHOG-INTERACTING PROTEIN HEDGEHOG-INTERACTING PROTEIN protein-binding activity modulator#PC00095 HUMAN|HGNC=28143|UniProtKB=Q53S58 Q53S58 TMEM177 PTHR21824:SF4 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 177 HUMAN|HGNC=40021|UniProtKB=Q8NCS4 Q8NCS4 TMEM35B PTHR13163:SF2 SPINAL CORD EXPRESSION PROTEIN 4 TRANSMEMBRANE PROTEIN 35B HUMAN|HGNC=2377|UniProtKB=Q6P2C8 Q6P2C8 MED27 PTHR13130:SF4 34 KDA TRANSCRIPTIONAL CO-ACTIVATOR-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 27 transcription cofactor#PC00217 HUMAN|HGNC=8632|UniProtKB=P40424 P40424 PBX1 PTHR11850:SF89 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;sensory system development#GO:0048880;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;neuron development#GO:0048666;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;visual system development#GO:0150063;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>Pbx1#P06729 HUMAN|HGNC=11327|UniProtKB=Q08945 Q08945 SSRP1 PTHR45849:SF1 FACT COMPLEX SUBUNIT SSRP1 FACT COMPLEX SUBUNIT SSRP1 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=33700|UniProtKB=A6NFY4 A6NFY4 NEMP2 PTHR13598:SF3 UNCHARACTERIZED NUCLEAR ENVELOPE INTEGRAL MEMBRANE PROTEIN 2 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=10600|UniProtKB=P51168 P51168 SCNN1B PTHR11690:SF18 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT BETA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=18583|UniProtKB=Q9ULR3 Q9ULR3 PPM1H PTHR13832:SF287 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1H hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=18927|UniProtKB=Q3LI76 Q3LI76 KRTAP15-1 PTHR19051:SF18 KERATIN-ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 15-1 structural protein#PC00211 HUMAN|HGNC=4818|UniProtKB=Q92839 Q92839 HAS1 PTHR22913:SF4 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 1 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;extracellular matrix organization#GO:0030198;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;carbohydrate biosynthetic process#GO:0016051;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;polysaccharide metabolic process#GO:0005976;extracellular structure organization#GO:0043062;cellular carbohydrate metabolic process#GO:0044262;glycosaminoglycan biosynthetic process#GO:0006024;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;cellular polysaccharide biosynthetic process#GO:0033692;cellular polysaccharide metabolic process#GO:0044264;small molecule metabolic process#GO:0044281 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=7873|UniProtKB=P35228 P35228 NOS2 PTHR19384:SF56 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE, INDUCIBLE nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;organic cyclic compound binding#GO:0097159;binding#GO:0005488;catalytic activity#GO:0003824;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;cyclic nucleotide metabolic process#GO:0009187;system process#GO:0003008;positive regulation of cellular metabolic process#GO:0031325;purine nucleotide biosynthetic process#GO:0006164;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;nucleoside phosphate metabolic process#GO:0006753;alpha-amino acid metabolic process#GO:1901605;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;carboxylic acid catabolic process#GO:0046395;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;purine nucleotide metabolic process#GO:0006163;oxoacid metabolic process#GO:0043436;regulation of lyase activity#GO:0051339;response to oxygen-containing compound#GO:1901700;interspecies interaction between organisms#GO:0044419;organonitrogen compound biosynthetic process#GO:1901566;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;organic acid metabolic process#GO:0006082;ribose phosphate biosynthetic process#GO:0046390;circulatory system process#GO:0003013;response to lipopolysaccharide#GO:0032496;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;organic acid catabolic process#GO:0016054;ribonucleotide biosynthetic process#GO:0009260;small molecule catabolic process#GO:0044282;positive regulation of phosphate metabolic process#GO:0045937;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;cellular amino acid metabolic process#GO:0006520;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;regulation of metabolic process#GO:0019222;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;blood circulation#GO:0008015;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;arginine catabolic process#GO:0006527;regulation of phosphate metabolic process#GO:0019220;second-messenger-mediated signaling#GO:0019932;organophosphate biosynthetic process#GO:0090407;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;response to lipid#GO:0033993;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;response to bacterium#GO:0009617;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;signaling#GO:0023052;metabolic process#GO:0008152;negative regulation of blood pressure#GO:0045776;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular amino acid catabolic process#GO:0009063;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;defense response to bacterium#GO:0042742;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;carboxylic acid metabolic process#GO:0019752;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 oxidoreductase#PC00176 PI3 kinase pathway#P00048>NOS#P01205 HUMAN|HGNC=23844|UniProtKB=A6QL63 A6QL63 BTBD11 PTHR46071:SF1 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN BTBD11 scaffold/adaptor protein#PC00226 HUMAN|HGNC=13733|UniProtKB=Q9H251 Q9H251 CDH23 PTHR24027:SF425 CADHERIN-23 CADHERIN-23-RELATED cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=26416|UniProtKB=Q96NI8 Q96NI8 ZNF570 PTHR24377:SF720 IP01015P-RELATED ZINC FINGER PROTEIN 570 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24163|UniProtKB=Q9BUH8 Q9BUH8 BEGAIN PTHR28664:SF2 TIGHT JUNCTION-ASSOCIATED PROTEIN 1 BRAIN-ENRICHED GUANYLATE KINASE-ASSOCIATED PROTEIN cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;regulation of neurotransmitter receptor activity#GO:0099601;chemical synaptic transmission, postsynaptic#GO:0099565;system process#GO:0003008;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;regulation of system process#GO:0044057;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;signaling#GO:0023052 cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical entity#GO:0110165 tight junction#PC00214 HUMAN|HGNC=18459|UniProtKB=Q9NXF8 Q9NXF8 ZDHHC7 PTHR22883:SF49 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC7 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=22918|UniProtKB=Q9H5J0 Q9H5J0 ZBTB3 PTHR24394:SF19 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29573|UniProtKB=Q86SQ0 Q86SQ0 PHLDB2 PTHR12156:SF21 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 2 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule-based process#GO:0032886;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular#GO:0005622 EGF receptor signaling pathway#P00018>Gab#P00563 HUMAN|HGNC=2335|UniProtKB=Q2VPA4 Q2VPA4 CR1L PTHR19325:SF534 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING COMPLEMENT COMPONENT RECEPTOR 1-LIKE PROTEIN HUMAN|HGNC=19599|UniProtKB=Q9H339 Q9H339 OR51B5 PTHR26450:SF76 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B5 transmembrane signal receptor#PC00197 HUMAN|HGNC=2847|UniProtKB=Q8WYQ5 Q8WYQ5 DGCR8 PTHR13482:SF3 MICRORNA PROCESSOR COMPLEX SUBUNIT DGCR8 MICROPROCESSOR COMPLEX SUBUNIT DGCR8 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;heme binding#GO:0020037;catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;double-stranded RNA binding#GO:0003725 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression#GO:0010468;regulation of gene expression, epigenetic#GO:0040029;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;gene silencing by miRNA#GO:0035195;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;gene silencing by RNA#GO:0031047;cellular process#GO:0009987;primary metabolic process#GO:0044238;production of miRNAs involved in gene silencing by miRNA#GO:0035196;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;posttranscriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=24990|UniProtKB=Q9Y2R0 Q9Y2R0 COA3 PTHR15642:SF3 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3 HOMOLOG, MITOCHONDRIAL chaperone#PC00072 HUMAN|HGNC=12253|UniProtKB=B7Z8K6 B7Z8K6 TRDC PTHR23266:SF116 IMMUNOGLOBULIN HEAVY CHAIN T CELL RECEPTOR DELTA CONSTANT protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=5634|UniProtKB=A0A075B7F0 A0A075B7F0 IGHV3OR16-10 PTHR23266:SF113 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|Ensembl=ENSG00000283967|UniProtKB=A0A1W2PP81 A0A1W2PP81 TAF11L7 PTHR13218:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TAFII28 DOMAIN-CONTAINING PROTEIN transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=17087|UniProtKB=O75144 O75144 ICOSLG PTHR24100:SF55 BUTYROPHILIN ICOS LIGAND protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=24810|UniProtKB=Q9NRQ5 Q9NRQ5 SMCO4 PTHR34644:SF2 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=4212|UniProtKB=Q9Y2T3 Q9Y2T3 GDA PTHR11271:SF6 GUANINE DEAMINASE GUANINE DEAMINASE cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;metal ion binding#GO:0046872;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 deaminase#PC00088 Purine metabolism#P02769>Guanine Deaminase#P03118;Xanthine and guanine salvage pathway#P02788>Guanine deaminase#P03249 HUMAN|HGNC=29867|UniProtKB=A6NK97 A6NK97 SLC22A20P PTHR24064:SF34 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 20 secondary carrier transporter#PC00258 HUMAN|HGNC=16370|UniProtKB=Q9H4L5 Q9H4L5 OSBPL3 PTHR10972:SF15 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 3 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;cholesterol binding#GO:0015485 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=25181|UniProtKB=Q96CE8 Q96CE8 TM4SF18 PTHR14198:SF14 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 18 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=25891|UniProtKB=Q8N4T8 Q8N4T8 CBR4 PTHR42760:SF117 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER CARBONYL REDUCTASE FAMILY MEMBER 4 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidation-reduction process#GO:0055114;metabolic process#GO:0008152 oxidoreductase#PC00176 HUMAN|HGNC=29308|UniProtKB=Q9HCM7 Q9HCM7 FBRSL1 PTHR14429:SF20 FIBROSIN FAMILY MEMBER FIBROSIN-1-LIKE PROTEIN HUMAN|HGNC=21067|UniProtKB=Q8IYR2 Q8IYR2 SMYD4 PTHR46165:SF2 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=11603|UniProtKB=P57082 P57082 TBX4 PTHR11267:SF29 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 specification of symmetry#GO:0009799;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;heart looping#GO:0001947;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;heart development#GO:0007507;embryonic heart tube development#GO:0035050;determination of heart left/right asymmetry#GO:0061371;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;determination of bilateral symmetry#GO:0009855;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;determination of left/right symmetry#GO:0007368;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=24999|UniProtKB=Q8IUR7 Q8IUR7 ARMC8 PTHR15651:SF7 ARMADILLO REPEAT-CONTAINING PROTEIN 8 ARMADILLO REPEAT-CONTAINING PROTEIN 8 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=26810|UniProtKB=Q63HQ2 Q63HQ2 EGFLAM PTHR10574:SF202 NETRIN/LAMININ-RELATED PIKACHURIN system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;tissue development#GO:0009888 extracellular matrix protein#PC00102 HUMAN|HGNC=549|UniProtKB=O75106 O75106 AOC2 PTHR10638:SF4 COPPER AMINE OXIDASE RETINA-SPECIFIC COPPER AMINE OXIDASE cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 organonitrogen compound metabolic process#GO:1901564;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 HUMAN|HGNC=6164|UniProtKB=O95965 O95965 ITGBL1 PTHR10082:SF3 INTEGRIN BETA SUBUNIT INTEGRIN BETA-LIKE PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;biological adhesion#GO:0022610;localization of cell#GO:0051674;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052 membrane protein complex#GO:0098796;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;focal adhesion#GO:0005925;integral component of plasma membrane#GO:0005887;cell-substrate junction#GO:0030055;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 HUMAN|HGNC=30434|UniProtKB=A2RUH7 A2RUH7 MYBPHL PTHR13817:SF49 TITIN MYOSIN-BINDING PROTEIN H-RELATED HUMAN|HGNC=7677|UniProtKB=Q96MG7 Q96MG7 NSMCE3 PTHR11736:SF51 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 3 HOMOLOG scaffold/adaptor protein#PC00226 HUMAN|HGNC=18418|UniProtKB=Q9NX55 Q9NX55 HYPK PTHR31184:SF2 HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER HUNTINGTIN-INTERACTING PROTEIN K negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;regulation of protein stability#GO:0031647;programmed cell death#GO:0012501;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;protein stabilization#GO:0050821;regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=44480|UniProtKB=K9M1U5 K9M1U5 IFNL4 PTHR31943:SF17 INTERLEUKIN-28 AND 29 INTERFERON LAMBDA-4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;immune response#GO:0006955;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 interleukin superfamily#PC00128 HUMAN|HGNC=24724|UniProtKB=Q6PGQ7 Q6PGQ7 BORA PTHR14728:SF2 UNCHARACTERIZED PROTEIN AURORA BOREALIS enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of protein modification process#GO:0031399;regulation of mitotic nuclear division#GO:0007088;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of microtubule-based process#GO:0032886;regulation of phosphate metabolic process#GO:0019220;mitotic spindle organization#GO:0007052;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;regulation of mitotic spindle organization#GO:0060236;phosphate-containing compound metabolic process#GO:0006796;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of microtubule cytoskeleton organization#GO:0070507;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;regulation of nuclear division#GO:0051783;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;microtubule-based process#GO:0007017;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;regulation of mitotic cell cycle#GO:0007346;regulation of transferase activity#GO:0051338 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229 HUMAN|HGNC=8488|UniProtKB=Q13416 Q13416 ORC2 PTHR14052:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 replication origin binding protein#PC00199 HUMAN|HGNC=30048|UniProtKB=O00625 O00625 PIR PTHR13903:SF8 PIRIN-RELATED PIRIN transcription cofactor#PC00217 HUMAN|HGNC=21421|UniProtKB=Q8NA23 Q8NA23 WDR31 PTHR19869:SF1 SPERMATID WD-REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 31 HUMAN|HGNC=28014|UniProtKB=A1A4G5 A1A4G5 LNP1 PTHR35667:SF1 LEUKEMIA NUP98 FUSION PARTNER 1 LEUKEMIA NUP98 FUSION PARTNER 1 HUMAN|HGNC=4670|UniProtKB=Q9BX10 Q9BX10 GTPBP2 PTHR43721:SF3 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation elongation factor#PC00222 HUMAN|HGNC=2351|UniProtKB=O75629 O75629 CREG1 PTHR13343:SF21 CREG1 PROTEIN PROTEIN CREG1 HUMAN|HGNC=17643|UniProtKB=Q9HD26 Q9HD26 GOPC PTHR16528:SF2 GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING PROTEIN ion channel binding#GO:0044325;protein binding#GO:0005515;binding#GO:0005488 cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;Golgi to plasma membrane transport#GO:0006893;amide transport#GO:0042886;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of protein transport#GO:0051223;negative regulation of cellular process#GO:0048523;regulation of protein localization#GO:0032880;protein localization to plasma membrane#GO:0072659;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to membrane#GO:0072657;regulation of protein localization to membrane#GO:1905475;vesicle-mediated transport#GO:0016192;negative regulation of transport#GO:0051051;protein localization to cell surface#GO:0034394;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;maintenance of location#GO:0051235;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;trans-Golgi network transport vesicle#GO:0030140;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=2395|UniProtKB=P53672 P53672 CRYBA2 PTHR11818:SF7 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A2 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=11928|UniProtKB=O75888 O75888 TNFSF13 PTHR15151:SF12 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 HUMAN|HGNC=10671|UniProtKB=Q86SQ7 Q86SQ7 SDCCAG8 PTHR34343:SF1 SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8 SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8 establishment or maintenance of cell polarity#GO:0007163;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;microtubule cytoskeleton organization#GO:0000226;tube development#GO:0035295;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;anatomical structure formation involved in morphogenesis#GO:0048646;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;cell differentiation#GO:0030154;establishment of cell polarity#GO:0030010;microtubule-based process#GO:0007017;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;tube morphogenesis#GO:0035239;anatomical structure development#GO:0048856;neuron migration#GO:0001764;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;generation of neurons#GO:0048699;cell migration#GO:0016477;locomotion#GO:0040011 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=6413|UniProtKB=P13645 P13645 KRT10 PTHR23239:SF137 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 10 HUMAN|HGNC=3664|UniProtKB=Q7Z6J4 Q7Z6J4 FGD2 PTHR12673:SF82 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 2 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=4552|UniProtKB=P24298 P24298 GPT PTHR11751:SF308 ALANINE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE 1 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 transaminase#PC00216 HUMAN|HGNC=10986|UniProtKB=P16260 P16260 SLC25A16 PTHR24089:SF705 SOLUTE CARRIER FAMILY 25 GRAVES DISEASE CARRIER PROTEIN mitochondrial carrier protein#PC00158 HUMAN|HGNC=29598|UniProtKB=Q9BQ69 Q9BQ69 MACROD1 PTHR11106:SF93 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED ADP-RIBOSE GLYCOHYDROLASE MACROD1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;cellular protein metabolic process#GO:0044267;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4271|UniProtKB=P48546 P48546 GIPR PTHR45620:SF5 PDF RECEPTOR-LIKE PROTEIN-RELATED GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=34006|UniProtKB=Q6ZWE6 Q6ZWE6 PLEKHM3 PTHR12326:SF10 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 3 HUMAN|HGNC=14281|UniProtKB=Q9HC73 Q9HC73 CRLF2 PTHR23036:SF163 CYTOKINE RECEPTOR CYTOKINE RECEPTOR-LIKE FACTOR 2 signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;growth factor receptor binding#GO:0070851;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;cytokine receptor binding#GO:0005126 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 membrane protein complex#GO:0098796;leaflet of membrane bilayer#GO:0097478;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=1557|UniProtKB=O95931 O95931 CBX7 PTHR47277:SF1 CHROMOBOX PROTEIN HOMOLOG 7 CHROMOBOX PROTEIN HOMOLOG 7 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16840|UniProtKB=Q9H944 Q9H944 MED20 PTHR12465:SF0 UBIQUITIN SPECIFIC PROTEASE HOMOLOG 49 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=8064|UniProtKB=P35658 P35658 NUP214 PTHR23193:SF21 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP214 signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=29187|UniProtKB=Q9UPS6 Q9UPS6 SETD1B PTHR45814:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1B histone modifying enzyme#PC00261 HUMAN|HGNC=19983|UniProtKB=Q86YS6 Q86YS6 RAB43 PTHR24073:SF653 DRAB5-RELATED RAS-RELATED PROTEIN RAB-43 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=5270|UniProtKB=P25685 P25685 DNAJB1 PTHR24078:SF568 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 1 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;unfolded protein binding#GO:0051082;binding#GO:0005488;transcription corepressor activity#GO:0003714;heat shock protein binding#GO:0031072;protein binding#GO:0005515;molecular function regulator#GO:0098772;chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544 'de novo' protein folding#GO:0006458;cellular process#GO:0009987;chaperone-mediated protein folding#GO:0061077;protein folding#GO:0006457 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=16130|UniProtKB=Q6UDR6 Q6UDR6 SPINT4 PTHR47898:SF1 KUNITZ-TYPE PROTEASE INHIBITOR 4 KUNITZ-TYPE PROTEASE INHIBITOR 4 protease inhibitor#PC00191 HUMAN|HGNC=17380|UniProtKB=Q9UJX3 Q9UJX3 ANAPC7 PTHR12558:SF36 CELL DIVISION CYCLE 16,23,27 ANAPHASE-PROMOTING COMPLEX SUBUNIT 7 cell division#GO:0051301;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=25509|UniProtKB=Q9P2N2 Q9P2N2 ARHGAP28 PTHR14963:SF5 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 28 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;contractile actin filament bundle assembly#GO:0030038;regulation of signaling#GO:0023051;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cellular response to stimulus#GO:0051716;stress fiber assembly#GO:0043149;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cell communication#GO:0007154;actomyosin structure organization#GO:0031032;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of small GTPase mediated signal transduction#GO:0051056;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 HUMAN|HGNC=4019|UniProtKB=Q9BYC5 Q9BYC5 FUT8 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 HUMAN|HGNC=16782|UniProtKB=Q7Z2T5 Q7Z2T5 TRMT1L PTHR10631:SF1 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRMT1-LIKE PROTEIN tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA methyltransferase#PC00033 HUMAN|HGNC=1884|UniProtKB=P13569 P13569 CFTR PTHR24223:SF19 ATP-BINDING CASSETTE SUB-FAMILY C CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;anion transport#GO:0006820;inorganic anion transport#GO:0015698 cytoplasm#GO:0005737;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=1503|UniProtKB=P42575 P42575 CASP2 PTHR10454:SF151 CASPASE CASPASE-2 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=29856|UniProtKB=Q9GZU8 Q9GZU8 PSME3IP1 PTHR13495:SF0 NEFA-INTERACTING NUCLEAR PROTEIN NIP30 PSME3-INTERACTING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=16675|UniProtKB=O43423 O43423 ANP32C PTHR11375:SF15 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER C protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 cellular localization#GO:0051641;regulation of apoptotic process#GO:0042981;transport#GO:0006810;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of biological process#GO:0050789;localization#GO:0051179;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;nucleocytoplasmic transport#GO:0006913;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;nuclear transport#GO:0051169;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=2475|UniProtKB=P01034 P01034 CST3 PTHR46186:SF10 CYSTATIN CYSTATIN-C extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=51829|UniProtKB=P0DN79 P0DN79 CBSL PTHR10314:SF8 CYSTATHIONINE BETA-SYNTHASE CYSTATHIONINE BETA-SYNTHASE-RELATED heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159 oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 lyase#PC00144 Cysteine biosynthesis#P02737>O-Acetylserine-lyase#P02887 HUMAN|HGNC=7865|UniProtKB=Q96S42 Q96S42 NODAL PTHR11848:SF159 TGF-BETA FAMILY NODAL HOMOLOG receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;receptor serine/threonine kinase binding#GO:0033612;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=6398|UniProtKB=O15131 O15131 KPNA5 PTHR23316:SF10 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-6 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|Ensembl=ENSG00000283361|UniProtKB=A0A1B0GU71 A0A1B0GU71 CFAP97D2 PTHR33768:SF7 MIP11318P SI:DKEY-83M22.7 HUMAN|HGNC=30168|UniProtKB=Q15084 Q15084 PDIA6 PTHR45815:SF3 PROTEIN DISULFIDE-ISOMERASE A6 PROTEIN DISULFIDE-ISOMERASE A6 chaperone#PC00072 HUMAN|HGNC=33267|UniProtKB=Q5HYN5 Q5HYN5 CT45A1 PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED CANCER/TESTIS ANTIGEN FAMILY 45 MEMBER A1-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 RNA helicase#PC00032 HUMAN|HGNC=3512|UniProtKB=Q16394 Q16394 EXT1 PTHR11062:SF97 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-1 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=814|UniProtKB=P20020 P20020 ATP2B1 PTHR24093:SF245 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 1 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;binding#GO:0005488;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=5105|UniProtKB=Q00056 Q00056 HOXA4 PTHR45771:SF2 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-A4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=21705|UniProtKB=O75223 O75223 GGCT PTHR12935:SF0 UNCHARACTERIZED GAMMA-GLUTAMYLCYCLOTRANSFERASE lyase activity#GO:0016829;catalytic activity#GO:0003824 HUMAN|HGNC=10838|UniProtKB=Q15464 Q15464 SHB PTHR15127:SF31 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN B protein binding#GO:0005515;binding#GO:0005488 HUMAN|HGNC=6851|UniProtKB=Q12852 Q12852 MAP3K12 PTHR44329:SF17 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 12 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 HUMAN|HGNC=27289|UniProtKB=A4GXA9 A4GXA9 EME2 PTHR21077:SF6 EME1 PROTEIN CROSSOVER JUNCTION ENDONUCLEASE EME2-RELATED DNA repair#GO:0006281;nuclear division#GO:0000280;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;replication fork processing#GO:0031297;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;mitotic DNA integrity checkpoint#GO:0044774;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;reproduction#GO:0000003;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;intra-S DNA damage checkpoint#GO:0031573;mitotic cell cycle process#GO:1903047;meiotic chromosome separation#GO:0051307;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;cellular nitrogen compound biosynthetic process#GO:0044271;reciprocal meiotic recombination#GO:0007131;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;cell cycle phase#GO:0022403;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;macromolecule biosynthetic process#GO:0009059;mitotic DNA damage checkpoint#GO:0044773;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;negative regulation of mitotic cell cycle#GO:0045930;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;biological phase#GO:0044848;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA replication#GO:0006260;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=4025|UniProtKB=O00168 O00168 FXYD1 PTHR14132:SF12 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA PHOSPHOLEMMAN cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of sodium ion transport#GO:0002028;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;sodium ion transport#GO:0006814;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;sodium ion transmembrane transport#GO:0035725 primary active transporter#PC00068 HUMAN|HGNC=578|UniProtKB=Q02410 Q02410 APBA1 PTHR12345:SF14 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 1 amyloid-beta binding#GO:0001540;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084;Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093 HUMAN|HGNC=24001|UniProtKB=Q8NDC4 Q8NDC4 MORN4 PTHR46614:SF1 MORN REPEAT-CONTAINING PROTEIN 4 MORN REPEAT-CONTAINING PROTEIN 4 HUMAN|HGNC=22467|UniProtKB=A6NGH8 A6NGH8 ANKRD61 PTHR24197:SF48 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 HUMAN|HGNC=13915|UniProtKB=Q9BXR3 Q9BXR3 ERVK-6 PTHR41694:SF4 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 10 POL PROTEIN-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 viral or transposable element protein#PC00237 HUMAN|HGNC=6389|UniProtKB=Q9BW19 Q9BW19 KIFC1 PTHR24115:SF931 KINESIN-RELATED KINESIN-LIKE PROTEIN KIFC1 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;mitotic spindle assembly#GO:0090307;movement of cell or subcellular component#GO:0006928;spindle assembly#GO:0051225;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=6844|UniProtKB=P45985 P45985 MAP2K4 PTHR48013:SF23 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of JNK cascade#GO:0046330;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;positive regulation of protein serine/threonine kinase activity#GO:0071902;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 non-receptor serine/threonine protein kinase#PC00167 FAS signaling pathway#P00020>MKK4#P00610;CCKR signaling map#P06959>MAP2K4#P07074;p38 MAPK pathway#P05918>MKK4#P06034;Huntington disease#P00029>MAPKK4#P00787;Ras Pathway#P04393>MKK4/7#P04565;Gonadotropin-releasing hormone receptor pathway#P06664>MKK4/7#P06760;Huntington disease#P00029>SEK-1#P00792;Apoptosis signaling pathway#P00006>SEK1#P00266;Angiogenesis#P00005>JNKK1#P00199;Toll receptor signaling pathway#P00054>MKK4#P01366;FGF signaling pathway#P00021>MKK4,7#P00637;Integrin signalling pathway#P00034>MEK#P00925;EGF receptor signaling pathway#P00018>MKK4,7#P00555;Oxidative stress response#P00046>MKK4#P01138;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 HUMAN|HGNC=11834|UniProtKB=P29401 P29401 TKT PTHR43195:SF3 TRANSKETOLASE TRANSKETOLASE cation binding#GO:0043169;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glucose 6-phosphate metabolic process#GO:0051156;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;oxidation-reduction process#GO:0055114;organophosphate metabolic process#GO:0019637;NADP metabolic process#GO:0006739;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transketolase#PC00221 Pentose phosphate pathway#P02762>Transketolase#P03082 HUMAN|HGNC=12197|UniProtKB=A0A075B6H5 A0A075B6H5 TRBV20OR9-2 PTHR23268:SF11 T-CELL RECEPTOR BETA CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=24825|UniProtKB=Q9BVC4 Q9BVC4 MLST8 PTHR19842:SF0 G BETA-LIKE PROTEIN GBL TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;intracellular signal transduction#GO:0035556;actin cytoskeleton organization#GO:0030036;signaling#GO:0023052;TOR signaling#GO:0031929 TORC2 complex#GO:0031932;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=17920|UniProtKB=Q96C03 Q96C03 MIEF2 PTHR16451:SF11 MITOCHONDRIAL DYNAMICS PROTEINS 49/51 FAMILY MEMBER MITOCHONDRIAL DYNAMICS PROTEIN MID49 positive regulation of organelle organization#GO:0010638;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of mitochondrion organization#GO:0010821;organelle organization#GO:0006996;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;positive regulation of biological process#GO:0048518;mitochondrial fission#GO:0000266 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=26727|UniProtKB=Q4G0M1 Q4G0M1 ERFE PTHR24019:SF11 ADIPOLIN ERYTHROFERRONE receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 positive regulation of signal transduction#GO:0009967;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;positive regulation of transmembrane transport#GO:0034764;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of transmembrane transport#GO:0034762;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;cellular metabolic process#GO:0044237;positive regulation of transport#GO:0051050;negative regulation of metabolic process#GO:0009892;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;carbohydrate transmembrane transport#GO:0034219;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;cellular carbohydrate metabolic process#GO:0044262;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;small molecule biosynthetic process#GO:0044283;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;monosaccharide metabolic process#GO:0005996;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;regulation of signaling#GO:0023051;transport#GO:0006810;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;carbohydrate transport#GO:0008643;positive regulation of response to stimulus#GO:0048584;organic substance transport#GO:0071702;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;carbohydrate metabolic process#GO:0005975;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;carbohydrate biosynthetic process#GO:0016051;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;negative regulation of biosynthetic process#GO:0009890;transmembrane transport#GO:0055085;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;glucose metabolic process#GO:0006006;regulation of glucose metabolic process#GO:0010906;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;hexose metabolic process#GO:0019318 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 HUMAN|HGNC=28518|UniProtKB=Q6UXV1 Q6UXV1 IZUMO2 PTHR47745:SF1 IZUMO SPERM-EGG FUSION PROTEIN 2 IZUMO SPERM-EGG FUSION PROTEIN 2 HUMAN|HGNC=25121|UniProtKB=Q69YL0 Q69YL0 NCBP2AS2 PTHR41161:SF1 PROTEIN NCBP2AS2 PROTEIN NCBP2AS2 HUMAN|HGNC=4951|UniProtKB=P79483 P79483 HLA-DRB3 PTHR19944:SF84 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR BETA 3 CHAIN-RELATED major histocompatibility complex protein#PC00149 HUMAN|HGNC=24846|UniProtKB=Q8NHY3 Q8NHY3 GAS2L2 PTHR46756:SF14 TRANSGELIN GAS2-LIKE PROTEIN 2 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;tubulin binding#GO:0015631;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;protein binding#GO:0005515;microtubule binding#GO:0008017;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 HUMAN|HGNC=18696|UniProtKB=Q96RK1 Q96RK1 CITED4 PTHR17045:SF5 MELANOCYTE SPECIFIC GENE RELATED CITED CBP/P300-INTERACTING TRANSACTIVATOR 4 transcription cofactor#PC00217 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 HUMAN|HGNC=5758|UniProtKB=A0A0B4J1Z2 A0A0B4J1Z2 IGKV1D-43 PTHR23267:SF216 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=6767|UniProtKB=Q15797 Q15797 SMAD1 PTHR13703:SF23 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;ubiquitin protein ligase binding#GO:0031625;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;nucleobase-containing compound metabolic process#GO:0006139;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;response to BMP#GO:0071772;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;BMP signaling pathway#GO:0030509;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;response to growth factor#GO:0070848;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to growth factor stimulus#GO:0071363;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Wnt signaling pathway#P00057>Smad4#P01455;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 HUMAN|HGNC=24306|UniProtKB=Q96RS6 Q96RS6 NUDCD1 PTHR21664:SF1 CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66 NUDC DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=1434|UniProtKB=P05937 P05937 CALB1 PTHR19972:SF14 CALBINDIN CALBINDIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of signaling#GO:0023051;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;synaptic signaling#GO:0099536;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;anatomical structure homeostasis#GO:0060249;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular cation homeostasis#GO:0030003;trans-synaptic signaling#GO:0099537;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular ion homeostasis#GO:0006873;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;cellular chemical homeostasis#GO:0055082;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;metal ion homeostasis#GO:0055065 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;terminal bouton#GO:0043195;dendrite#GO:0030425;cytosol#GO:0005829;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane#GO:0005886 calmodulin-related#PC00061 HUMAN|HGNC=8301|UniProtKB=Q96R69 Q96R69 OR4F4 PTHR48002:SF51 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4F17-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=13974|UniProtKB=P18615 P18615 NELFE PTHR17250:SF0 NEGATIVE ELONGATION FACTOR E NEGATIVE ELONGATION FACTOR E negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of DNA-templated transcription, elongation#GO:0032784;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;regulation of transcription elongation from RNA polymerase II promoter#GO:0034243;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;transcription elongation from RNA polymerase II promoter#GO:0006368;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023 HUMAN|HGNC=28336|UniProtKB=Q9BRU2 Q9BRU2 TCEAL7 PTHR14754:SF5 TRANSCRIPTION ELONGATION FACTOR A TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 7 general transcription factor#PC00259 HUMAN|HGNC=4913|UniProtKB=O00291 O00291 HIP1 PTHR10407:SF14 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN-INTERACTING PROTEIN 1 cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;actin binding#GO:0003779 cellular component biogenesis#GO:0044085;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;positive regulation of proteolysis#GO:0045862;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;actin filament-based process#GO:0030029;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of endocytosis#GO:0030100;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;positive regulation of transport#GO:0051050;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;programmed cell death#GO:0012501;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein-containing complex assembly#GO:0065003;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;regulation of transport#GO:0051049;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;supramolecular fiber organization#GO:0097435;cell death#GO:0008219;actin filament organization#GO:0007015;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell death#GO:0010942 synapse#GO:0045202;postsynaptic membrane#GO:0045211;intracellular membrane-bounded organelle#GO:0043231;extrinsic component of plasma membrane#GO:0019897;cortical actin cytoskeleton#GO:0030864;actin cortical patch#GO:0030479;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;non-membrane-bounded organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;postsynapse#GO:0098794;presynapse#GO:0098793;cortical cytoskeleton#GO:0030863;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell cortex#GO:0005938;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;synaptic membrane#GO:0097060;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 Huntington disease#P00029>Hip-1#P00765 HUMAN|HGNC=5896|UniProtKB=P01715 P01715 IGLV3-1 PTHR23267:SF315 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-1 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=19334|UniProtKB=Q8NBA8 Q8NBA8 DTWD2 PTHR21392:SF0 UNCHARACTERIZED TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 HUMAN|HGNC=38708|UniProtKB=C9JBD0 C9JBD0 KRBOX1 PTHR23232:SF103 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN 1 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3381|UniProtKB=P16452 P16452 EPB42 PTHR11590:SF44 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE ERYTHROCYTE MEMBRANE PROTEIN BAND 4.2 transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular protein modification process#GO:0006464 transferase#PC00220 HUMAN|HGNC=37203|UniProtKB=B2RUY7 B2RUY7 VWC2L PTHR46252:SF2 BRORIN FAMILY MEMBER VON WILLEBRAND FACTOR C DOMAIN-CONTAINING PROTEIN 2-LIKE signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;negative regulation of cellular response to growth factor stimulus#GO:0090288;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;negative regulation of signal transduction#GO:0009968 membrane protein complex#GO:0098796;extracellular region#GO:0005576;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;transmembrane transporter complex#GO:1902495;intrinsic component of plasma membrane#GO:0031226;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 HUMAN|HGNC=20300|UniProtKB=O43482 O43482 OIP5 PTHR16431:SF3 NEUROGENIC PROTEIN MASTERMIND PROTEIN MIS18-BETA protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cellular protein-containing complex assembly#GO:0034622;chromatin assembly or disassembly#GO:0006333;histone exchange#GO:0043486;nucleosome organization#GO:0034728;macromolecule localization#GO:0033036;nucleosome assembly#GO:0006334;cellular protein localization#GO:0034613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;chromosome segregation#GO:0007059;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;chromosome organization#GO:0051276;ATP-dependent chromatin remodeling#GO:0043044;chromatin organization#GO:0006325;protein localization to organelle#GO:0033365;chromatin remodeling#GO:0006338;protein-containing complex subunit organization#GO:0043933;DNA replication-independent nucleosome organization#GO:0034724 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;chromosome#GO:0005694;intracellular#GO:0005622;chromosome, centromeric region#GO:0000775;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11353|UniProtKB=Q99469 Q99469 STAC PTHR15135:SF3 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN ion channel binding#GO:0044325;protein binding#GO:0005515;binding#GO:0005488 positive regulation of ion transport#GO:0043270;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of metal ion transport#GO:0010959;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of molecular function#GO:0044093;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;establishment of localization#GO:0051234;skeletal muscle contraction#GO:0003009;regulation of molecular function#GO:0065009;divalent inorganic cation transport#GO:0072511;positive regulation of transmembrane transport#GO:0034764;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;protein localization to plasma membrane#GO:0072659;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;protein localization to membrane#GO:0072657;calcium ion transmembrane transport#GO:0070588;regulation of protein localization to membrane#GO:1905475;ion transport#GO:0006811;regulation of calcium ion transport#GO:0051924;positive regulation of ion transmembrane transporter activity#GO:0032414;positive regulation of transport#GO:0051050;positive regulation of calcium ion transport#GO:0051928;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;striated muscle contraction#GO:0006941;ion transmembrane transport#GO:0034220;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;protein localization to cell periphery#GO:1990778;regulation of ion transmembrane transport#GO:0034765;cellular macromolecule localization#GO:0070727;positive regulation of transporter activity#GO:0032411;regulation of cellular process#GO:0050794;positive regulation of ion transmembrane transport#GO:0034767;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of ion transport#GO:0043269;muscle system process#GO:0003012;muscle contraction#GO:0006936 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 HUMAN|HGNC=5747|UniProtKB=A0A0B4J2D9 A0A0B4J2D9 IGKV1D-13 PTHR23267:SF411 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-13-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=2855|UniProtKB=O75912 O75912 DGKI PTHR11255:SF92 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE IOTA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;regulation of signaling#GO:0023051;lipid modification#GO:0030258;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;trans-synaptic signaling#GO:0099537;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cellular lipid metabolic process#GO:0044255 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 kinase#PC00137 HUMAN|HGNC=18876|UniProtKB=P59539 P59539 TAS2R45 PTHR11394:SF134 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 45 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=9219|UniProtKB=Q12837 Q12837 POU4F2 PTHR11636:SF41 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=10762|UniProtKB=Q53H47 Q53H47 SETMAR PTHR46060:SF2 MARINER MOS1 TRANSPOSASE-LIKE PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR viral or transposable element protein#PC00237 HUMAN|HGNC=28214|UniProtKB=Q7Z6J6 Q7Z6J6 FRMD5 PTHR23280:SF5 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN 5 HUMAN|HGNC=29868|UniProtKB=Q9UI15 Q9UI15 TAGLN3 PTHR18959:SF57 CALPONIN/TRANSGELIN TRANSGELIN-3 non-motor actin binding protein#PC00165 HUMAN|HGNC=5412|UniProtKB=P13164 P13164 IFITM1 PTHR13999:SF6 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 1 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to cytokine#GO:0034097;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;innate immune response#GO:0045087;defense response to virus#GO:0051607;cytokine-mediated signaling pathway#GO:0019221;defense response#GO:0006952;signaling#GO:0023052;immune effector process#GO:0002252;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;cell communication#GO:0007154;cellular process#GO:0009987;response to type I interferon#GO:0034340;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;type I interferon signaling pathway#GO:0060337 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=4187|UniProtKB=P02774 P02774 GC PTHR11385:SF11 SERUM ALBUMIN-RELATED VITAMIN D-BINDING PROTEIN lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 transfer/carrier protein#PC00219 Vitamin D metabolism and pathway#P04396>DBP#P04600 HUMAN|HGNC=19044|UniProtKB=A0AVI2 A0AVI2 FER1L5 PTHR12546:SF34 FER-1-LIKE FER-1-LIKE PROTEIN 5 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543 vesicle fusion#GO:0006906;negative regulation of biological process#GO:0048519;muscle cell differentiation#GO:0042692;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;plasma membrane organization#GO:0007009;transport#GO:0006810;developmental process#GO:0032502;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;wound healing#GO:0042060;regulation of vesicle-mediated transport#GO:0060627;muscle structure development#GO:0061061;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transport#GO:0051049;establishment of localization#GO:0051234;vesicle organization#GO:0016050;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;leukocyte activation#GO:0045321;organelle fusion#GO:0048284;cellular developmental process#GO:0048869;immune response#GO:0006955;phagocytosis#GO:0006909;vesicle-mediated transport#GO:0016192;negative regulation of transport#GO:0051051;cellular component organization#GO:0016043;cellular process#GO:0009987;cell activation involved in immune response#GO:0002263;localization#GO:0051179;cell activation#GO:0001775;muscle cell development#GO:0055001;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;immune system process#GO:0002376;response to stimulus#GO:0050896;membrane fusion#GO:0061025;response to wounding#GO:0009611;response to stress#GO:0006950;leukocyte activation involved in immune response#GO:0002366;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;sarcolemma#GO:0042383 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=14785|UniProtKB=Q8NGH7 Q8NGH7 OR52L1 PTHR26450:SF96 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52L1 transmembrane signal receptor#PC00197 HUMAN|HGNC=17064|UniProtKB=O00472 O00472 ELL2 PTHR23288:SF8 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL2 general transcription factor#PC00259 HUMAN|HGNC=6850|UniProtKB=Q16584 Q16584 MAP3K11 PTHR44329:SF46 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 11 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;MAP kinase kinase activity#GO:0004708;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;regulation of MAP kinase activity#GO:0043405;JNK cascade#GO:0007254;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;programmed cell death#GO:0012501;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of programmed cell death#GO:0043068;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;cell death#GO:0008219;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;positive regulation of protein serine/threonine kinase activity#GO:0071902;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;microtubule-based process#GO:0007017;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell death#GO:0010942;regulation of transferase activity#GO:0051338;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;centriole#GO:0005814;intracellular organelle#GO:0043229;centrosome#GO:0005813 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>MAP3K11#P07139;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 HUMAN|HGNC=30245|UniProtKB=Q9BXC1 Q9BXC1 GPR174 PTHR24232:SF86 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 174-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=26437|UniProtKB=Q96NA8 Q96NA8 TSNARE1 PTHR19957:SF212 SYNTAXIN T-SNARE DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 SNARE protein#PC00034 HUMAN|HGNC=8766|UniProtKB=Q8WUM4 Q8WUM4 PDCD6IP PTHR23030:SF39 PCD6 INTERACTING PROTEIN-RELATED PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN membrane traffic protein#PC00150 HUMAN|HGNC=321|UniProtKB=P35573 P35573 AGL PTHR10569:SF2 GLYCOGEN DEBRANCHING ENZYME GLYCOGEN DEBRANCHING ENZYME transferase activity, transferring hexosyl groups#GO:0016758;glucosidase activity#GO:0015926;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;transferase activity, transferring glycosyl groups#GO:0016757 glucan metabolic process#GO:0044042;macromolecule catabolic process#GO:0009057;glycogen metabolic process#GO:0005977;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;cellular glucan metabolic process#GO:0006073;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;cellular catabolic process#GO:0044248 HUMAN|HGNC=6219|UniProtKB=Q16322 Q16322 KCNA10 PTHR11537:SF44 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 10 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=19700|UniProtKB=Q969H4 Q969H4 CNKSR1 PTHR12844:SF10 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 1 CCKR signaling map#P06959>CNKSR1#P07029 HUMAN|HGNC=17440|UniProtKB=Q8NHY2 Q8NHY2 COP1 PTHR44080:SF1 E3 UBIQUITIN-PROTEIN LIGASE COP1 E3 UBIQUITIN-PROTEIN LIGASE COP1 ubiquitin-protein ligase#PC00234 P53 pathway feedback loops 1#P04392>Cop-1#P04540;P53 pathway feedback loops 1#P04392>Cop-1#G04683 HUMAN|HGNC=367|UniProtKB=Q92667 Q92667 AKAP1 PTHR22948:SF65 TUDOR DOMAIN CONTAINING PROTEIN A-KINASE ANCHOR PROTEIN 1, MITOCHONDRIAL scaffold/adaptor protein#PC00226 CCKR signaling map#P06959>AKAP#P07184 HUMAN|HGNC=23218|UniProtKB=Q8IWJ2 Q8IWJ2 GCC2 PTHR18902:SF25 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;protein targeting to lysosome#GO:0006622;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;regulation of protein transport#GO:0051223;regulation of protein localization#GO:0032880;establishment of protein localization to vacuole#GO:0072666;Golgi organization#GO:0007030;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;microtubule organizing center organization#GO:0031023;cytosolic transport#GO:0016482;protein localization#GO:0008104;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;Golgi apparatus#GO:0005794;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=9253|UniProtKB=P62937 P62937 PPIA PTHR11071:SF490 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=17350|UniProtKB=O60508 O60508 CDC40 PTHR43979:SF1 PRE-MRNA-PROCESSING FACTOR 17 PRE-MRNA-PROCESSING FACTOR 17 RNA splicing factor#PC00148 HUMAN|HGNC=15029|UniProtKB=Q8NGY2 Q8NGY2 OR6K2 PTHR26451:SF68 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 6K2 HUMAN|HGNC=4042|UniProtKB=Q9ULV1 Q9ULV1 FZD4 PTHR11309:SF23 FRIZZLED FRIZZLED-4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 HUMAN|HGNC=11779|UniProtKB=Q08188 Q08188 TGM3 PTHR11590:SF36 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE E transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular protein modification process#GO:0006464 transferase#PC00220 HUMAN|HGNC=14806|UniProtKB=Q8NGP4 Q8NGP4 OR5M3 PTHR48018:SF147 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=12446|UniProtKB=Q06418 Q06418 TYRO3 PTHR24416:SF279 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RECEPTOR TYRO3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;phagocytosis#GO:0006909;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=5212|UniProtKB=P37058 P37058 HSD17B3 PTHR43899:SF7 RH59310P TESTOSTERONE 17-BETA-DEHYDROGENASE 3 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 HUMAN|HGNC=14118|UniProtKB=Q9BZJ3 Q9BZJ3 TPSD1 PTHR24256:SF511 TRYPTASE-RELATED TRYPTASE DELTA serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|Ensembl=ENSG00000284016|UniProtKB=A0A5K1VDZ0 A0A5K1VDZ0 LOC112267881 PTHR11738:SF113 MHC CLASS I NK CELL RECEPTOR KIR2DL PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=2582|UniProtKB=P35663 P35663 CYLC1 PTHR16742:SF1 CYCLICIN CYLICIN-1 acrosomal vesicle#GO:0001669;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 structural protein#PC00211 HUMAN|HGNC=29536|UniProtKB=O60336 O60336 MAPKBP1 PTHR44813:SF1 MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1 MITOGEN-ACTIVATED PROTEIN KINASE-BINDING PROTEIN 1 HUMAN|HGNC=21589|UniProtKB=Q8N3H0 Q8N3H0 TAFA2 PTHR31770:SF1 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-2 receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=4105|UniProtKB=P0CL82 P0CL82 GAGE12I PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=26699|UniProtKB=Q86WS3 Q86WS3 OOSP2 PTHR14380:SF7 PLACENTA-SPECIFIC PROTEIN 1 OOCYTE-SECRETED PROTEIN 2 HUMAN|HGNC=21569|UniProtKB=Q8N1K5 Q8N1K5 THEMIS PTHR15215:SF1 CABIT DOMAIN-CONTAINING PROTEIN PROTEIN THEMIS antigen receptor-mediated signaling pathway#GO:0050851;immune response-regulating signaling pathway#GO:0002764;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;activation of immune response#GO:0002253;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;immune response-activating cell surface receptor signaling pathway#GO:0002429;signaling#GO:0023052;positive regulation of biological process#GO:0048518;T cell receptor signaling pathway#GO:0050852 HUMAN|HGNC=12876|UniProtKB=Q9NY26 Q9NY26 SLC39A1 PTHR11040:SF58 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP1 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;transition metal ion transport#GO:0000041;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=25120|UniProtKB=Q2T9K0 Q2T9K0 TMEM44 PTHR16201:SF41 SEVEN TRANSMEMBRANE PROTEIN 1-RELATED TRANSMEMBRANE PROTEIN 44 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=13275|UniProtKB=P0DPD6 P0DPD6 ECE2 PTHR11733:SF127 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED EEF1AKMT4-ECE2 READTHROUGH TRANSCRIPT PROTEIN-RELATED metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 HUMAN|HGNC=10382|UniProtKB=P04844 P04844 RPN2 PTHR12640:SF0 RIBOPHORIN II DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 HUMAN|HGNC=15168|UniProtKB=Q96R67 Q96R67 OR4C12 PTHR48002:SF105 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C12 transmembrane signal receptor#PC00197 HUMAN|HGNC=12757|UniProtKB=P61964 P61964 WDR5 PTHR22847:SF560 WD40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 5 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone methylation#GO:0016571;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;histone lysine methylation#GO:0034968;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;histone H3-K4 methylation#GO:0051568;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=14662|UniProtKB=Q96BH1 Q96BH1 RNF25 PTHR13198:SF4 RING FINGER PROTEIN 25 E3 UBIQUITIN-PROTEIN LIGASE RNF25 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=1555|UniProtKB=P45973 P45973 CBX5 PTHR22812:SF85 CHROMOBOX PROTEIN CHROMOBOX PROTEIN HOMOLOG 5 HUMAN|HGNC=21706|UniProtKB=Q8N2F6 Q8N2F6 ARMC10 PTHR15712:SF19 ARMADILLO REPEAT CONTAINING PROTEIN ARMADILLO REPEAT-CONTAINING PROTEIN 10 HUMAN|HGNC=4171|UniProtKB=P23769 P23769 GATA2 PTHR10071:SF149 TRANSCRIPTION FACTOR GATA FAMILY MEMBER ENDOTHELIAL TRANSCRIPTION FACTOR GATA-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of vasculature development#GO:1901342;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;circulatory system development#GO:0072359;regulation of multicellular organismal process#GO:0051239;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cell fate commitment#GO:0045165;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of angiogenesis#GO:0045766;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;regulation of anatomical structure morphogenesis#GO:0022603;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of angiogenesis#GO:0045765;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of developmental process#GO:0051094;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>GATA2/4#P06859 HUMAN|HGNC=30817|UniProtKB=Q6NTE8 Q6NTE8 MRNIP PTHR15863:SF2 MRN COMPLEX-INTERACTING PROTEIN MRN COMPLEX-INTERACTING PROTEIN HUMAN|HGNC=25990|UniProtKB=Q9C0C7 Q9C0C7 AMBRA1 PTHR22874:SF1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=6459|UniProtKB=Q9NSB4 Q9NSB4 KRT82 PTHR45616:SF12 FAMILY NOT NAMED KERATIN, TYPE II CUTICULAR HB2 HUMAN|HGNC=33264|UniProtKB=Q6ZWI9 Q6ZWI9 RFPL4B PTHR25462:SF287 BONUS, ISOFORM C-RELATED RET FINGER PROTEIN-LIKE 4B HUMAN|HGNC=14983|UniProtKB=Q96JP5 Q96JP5 ZFP91 PTHR46179:SF11 ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZFP91 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=19740|UniProtKB=Q96RV3 Q96RV3 PCNX1 PTHR12372:SF2 PECANEX PECANEX-LIKE PROTEIN 1 HUMAN|HGNC=218|UniProtKB=O95450 O95450 ADAMTS2 PTHR13723:SF141 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 2 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=8864|UniProtKB=P27918 P27918 CFP PTHR22906:SF37 PROPERDIN PROPERDIN HUMAN|HGNC=1593|UniProtKB=Q16589 Q16589 CCNG2 PTHR10177:SF60 CYCLINS CYCLIN-G2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 HUMAN|HGNC=3613|UniProtKB=P12314 P12314 FCGR1A PTHR11481:SF11 IMMUNOGLOBULIN FC RECEPTOR HIGH AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR I-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|Gene=OVOS2|UniProtKB=Q6IE36 Q6IE36 OVOS2 PTHR11412:SF150 MACROGLOBULIN / COMPLEMENT OVOSTATIN HOMOLOG 1-RELATED protease inhibitor#PC00191 HUMAN|HGNC=28521|UniProtKB=Q4G163 Q4G163 FBXO43 PTHR15493:SF1 F-BOX ONLY PROTEIN 5 AND 43 F-BOX ONLY PROTEIN 43 regulation of mitotic nuclear division#GO:0007088;negative regulation of biological process#GO:0048519;nuclear division#GO:0000280;cell cycle process#GO:0022402;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;regulation of nuclear division#GO:0051783;negative regulation of cell cycle#GO:0045786;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;regulation of meiotic cell cycle#GO:0051445;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;regulation of mitotic cell cycle#GO:0007346 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=13234|UniProtKB=Q9H305 Q9H305 CDIP1 PTHR23292:SF7 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR CELL DEATH-INDUCING P53-TARGET PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3282|UniProtKB=P60842 P60842 EIF4A1 PTHR24031:SF221 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A-I nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=4571|UniProtKB=P42261 P42261 GRIA1 PTHR18966:SF157 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1 amino acid binding#GO:0016597;cation channel activity#GO:0005261;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;glutamate binding#GO:0016595;ligand-gated channel activity#GO:0022834 membrane protein complex#GO:0098796;synapse#GO:0045202;somatodendritic compartment#GO:0036477;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;cell periphery#GO:0071944;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;postsynapse#GO:0098794;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019 HUMAN|HGNC=8536|UniProtKB=Q93086 Q93086 P2RX5 PTHR10125:SF12 P2X PURINOCEPTOR P2X PURINOCEPTOR 5 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=9760|UniProtKB=P62491 P62491 RAB11A PTHR47979:SF33 DRAB11-RELATED RAS-RELATED PROTEIN RAB-11A endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=2963|UniProtKB=O14576 O14576 DYNC1I1 PTHR12442:SF34 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 1 dynein heavy chain binding#GO:0045504;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;transport along microtubule#GO:0010970 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=32275|UniProtKB=Q7RTU0 Q7RTU0 TCF24 PTHR23349:SF48 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 24 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=10774|UniProtKB=P23246 P23246 SFPQ PTHR23189:SF51 RNA RECOGNITION MOTIF-CONTAINING SPLICING FACTOR, PROLINE- AND GLUTAMINE-RICH sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;RNA splicing, via transesterification reactions#GO:0000375;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=794|UniProtKB=P31939 P31939 ATIC PTHR11692:SF0 BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 De novo purine biosynthesis#P02738>AICAR transformylase#P02900;De novo purine biosynthesis#P02738>IMP cyclohydrolase#P02894 HUMAN|HGNC=8004|UniProtKB=O14786 O14786 NRP1 PTHR46806:SF4 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN NEUROPILIN-1 Axon guidance mediated by semaphorins#P00007>Neuropilin 1#P00338 HUMAN|HGNC=6416|UniProtKB=P02533 P02533 KRT14 PTHR23239:SF368 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 14 HUMAN|HGNC=17807|UniProtKB=Q9H9P2 Q9H9P2 CHODL PTHR14789:SF1 CHONDROLECTIN VARIANT CHODLFDELTAE. CHONDROLECTIN regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;cell projection organization#GO:0030030;positive regulation of cell projection organization#GO:0031346;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;positive regulation of neuron differentiation#GO:0045666;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;regulation of neuron differentiation#GO:0045664;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;generation of neurons#GO:0048699;positive regulation of multicellular organismal process#GO:0051240 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=26420|UniProtKB=Q86YE8 Q86YE8 ZNF573 PTHR24377:SF923 IP01015P-RELATED ZINC FINGER PROTEIN 573 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=17024|UniProtKB=Q9UIL8 Q9UIL8 PHF11 PTHR12420:SF4 PHD FINGER PROTEIN PHD FINGER PROTEIN 11 enzyme binding#GO:0019899;protein binding#GO:0005515;histone deacetylase binding#GO:0042826;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=30954|UniProtKB=Q8IW36 Q8IW36 ZNF695 PTHR24384:SF119 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 695 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=1312|UniProtKB=O95922 O95922 TTLL1 PTHR12241:SF31 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL1-RELATED cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=21605|UniProtKB=Q14151 Q14151 SAFB2 PTHR15683:SF4 SCAFFOLD ATTACHMENT FACTOR B-RELATED SCAFFOLD ATTACHMENT FACTOR B2 sequence-specific DNA binding#GO:0043565;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;mRNA processing#GO:0006397;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=17452|UniProtKB=Q9HBK9 Q9HBK9 AS3MT PTHR43675:SF8 ARSENITE METHYLTRANSFERASE ARSENITE METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155 HUMAN|HGNC=27578|UniProtKB=P0C7P0 P0C7P0 CISD3 PTHR46491:SF3 CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL HUMAN|HGNC=28734|UniProtKB=Q8IWE4 Q8IWE4 DCUN1D3 PTHR12281:SF24 RP42 RELATED DCN1-LIKE PROTEIN 3 enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=32926|UniProtKB=Q08ET2 Q08ET2 SIGLEC14 PTHR12035:SF109 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 14 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=9584|UniProtKB=P59533 P59533 TAS2R38 PTHR11394:SF52 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 38 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=29109|UniProtKB=A2RU30 A2RU30 TESPA1 PTHR17469:SF1 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN TESPA1 HUMAN|HGNC=21535|UniProtKB=Q9BZE4 Q9BZE4 GTPBP4 PTHR45759:SF1 NUCLEOLAR GTP-BINDING PROTEIN 1 NUCLEOLAR GTP-BINDING PROTEIN 1 HUMAN|HGNC=16230|UniProtKB=Q9NUD5 Q9NUD5 ZCCHC3 PTHR22639:SF2 GAG-RELATED PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3 viral or transposable element protein#PC00237 HUMAN|HGNC=25167|UniProtKB=Q96DZ7 Q96DZ7 TM4SF19 PTHR14198:SF22 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 19 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=3192|UniProtKB=Q05639 Q05639 EEF1A2 PTHR23115:SF228 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111 cellular macromolecule biosynthetic process#GO:0034645;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation factor#PC00223 HUMAN|HGNC=27570|UniProtKB=Q7Z6M3 Q7Z6M3 MILR1 PTHR11481:SF58 IMMUNOGLOBULIN FC RECEPTOR ALLERGIN-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=12024|UniProtKB=P16562 P16562 CRISP2 PTHR10334:SF388 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=6533|UniProtKB=O43679 O43679 LDB2 PTHR10378:SF8 LIM DOMAIN-BINDING PROTEIN LIM DOMAIN-BINDING PROTEIN 2 RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;activating transcription factor binding#GO:0033613;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 HUMAN|HGNC=20776|UniProtKB=Q9BUF5 Q9BUF5 TUBB6 PTHR11588:SF88 TUBULIN TUBULIN BETA-6 CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 HUMAN|HGNC=1759|UniProtKB=P19022 P19022 CDH2 PTHR24027:SF79 CADHERIN-23 CADHERIN-2 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167 cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;brain development#GO:0007420;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;synaptic signaling#GO:0099536;vasculature development#GO:0001944;central nervous system development#GO:0007417;axonogenesis#GO:0007409;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;regulation of multicellular organismal process#GO:0051239;blood vessel morphogenesis#GO:0048514;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;trans-synaptic signaling#GO:0099537;tube development#GO:0035295;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;synapse organization#GO:0050808;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;modulation of chemical synaptic transmission#GO:0050804;regulation of cell projection organization#GO:0031344;blood vessel development#GO:0001568;neuron development#GO:0048666;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;regulation of trans-synaptic signaling#GO:0099177;regulation of cell morphogenesis involved in differentiation#GO:0010769;head development#GO:0060322;neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;animal organ development#GO:0048513;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;system development#GO:0048731;neuron differentiation#GO:0030182;cell junction assembly#GO:0034329;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cell-cell signaling#GO:0007267;signaling#GO:0023052;cell-cell junction organization#GO:0045216;regulation of cell communication#GO:0010646;cell-cell junction assembly#GO:0007043;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;regulation of synaptic transmission, glutamatergic#GO:0051966;cell development#GO:0048468;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;synapse assembly#GO:0007416;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;generation of neurons#GO:0048699 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;presynaptic membrane#GO:0042734;extrinsic component of membrane#GO:0019898;asymmetric synapse#GO:0032279;apical part of cell#GO:0045177;cell leading edge#GO:0031252;intrinsic component of membrane#GO:0031224;intrinsic component of synaptic membrane#GO:0099240;intracellular#GO:0005622;lamellipodium#GO:0030027;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;intrinsic component of postsynaptic specialization membrane#GO:0098948;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;intrinsic component of postsynaptic membrane#GO:0098936;presynapse#GO:0098793;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;anchoring junction#GO:0070161;integral component of synaptic membrane#GO:0099699;cell junction#GO:0030054;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;integral component of postsynaptic specialization membrane#GO:0099060;presynaptic active zone#GO:0048786;integral component of postsynaptic membrane#GO:0099055;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;adherens junction#GO:0005912;cell-cell contact zone#GO:0044291;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=2742|UniProtKB=Q9UMR2 Q9UMR2 DDX19B PTHR47958:SF93 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX19B catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;ribonucleoprotein complex localization#GO:0071166;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=20266|UniProtKB=Q9Y673 Q9Y673 ALG5 PTHR10859:SF91 GLYCOSYL TRANSFERASE DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE glycosyltransferase#PC00111 TGF-beta signaling pathway#P00052>RSmads#P01292 HUMAN|HGNC=9216|UniProtKB=P20264 P20264 POU3F3 PTHR11636:SF125 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=7316|UniProtKB=Q01362 Q01362 MS4A2 PTHR23320:SF66 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT BETA transporter#PC00227 HUMAN|HGNC=7124|UniProtKB=Q16655 Q16655 MLANA PTHR15305:SF0 MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 HUMAN|HGNC=20507|UniProtKB=Q7L7L0 Q7L7L0 H2AW PTHR23430:SF220 HISTONE H2A HISTONE H2A TYPE 3 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=28409|UniProtKB=Q9BTE7 Q9BTE7 DCUN1D5 PTHR12281:SF6 RP42 RELATED DCN1-LIKE PROTEIN 5 enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=30349|UniProtKB=Q9Y535 Q9Y535 POLR3H PTHR12709:SF1 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;intracellular#GO:0005622;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;transferase complex#GO:1990234;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=27268|UniProtKB=Q8TC21 Q8TC21 ZNF596 PTHR24381:SF30 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 596 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23139|UniProtKB=Q8IUQ0 Q8IUQ0 CLVS1 PTHR10174:SF72 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CLAVESIN-1 phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 HUMAN|HGNC=30083|UniProtKB=Q6PIL6 Q6PIL6 KCNIP4 PTHR23055:SF30 CALCIUM BINDING PROTEINS KV CHANNEL-INTERACTING PROTEIN 4 HUMAN|HGNC=25656|UniProtKB=Q9NUJ1 Q9NUJ1 ABHD10 PTHR16138:SF7 MYCOPHENOLIC ACID ACYL-GLUCURONIDE ESTERASE, MITOCHONDRIAL MYCOPHENOLIC ACID ACYL-GLUCURONIDE ESTERASE, MITOCHONDRIAL esterase#PC00097 HUMAN|HGNC=6746|UniProtKB=Q14596 Q14596 NBR1 PTHR20930:SF2 OVARIAN CARCINOMA ANTIGEN CA125-RELATED NEXT TO BRCA1 GENE 1 PROTEIN protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 process utilizing autophagic mechanism#GO:0061919;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;intracellular#GO:0005622 HUMAN|HGNC=18939|UniProtKB=Q3LI73 Q3LI73 KRTAP19-4 PTHR38140:SF5 KERATIN-ASSOCIATED PROTEIN 19-3-RELATED KERATIN-ASSOCIATED PROTEIN 19-3-RELATED HUMAN|HGNC=18506|UniProtKB=Q96P31 Q96P31 FCRL3 PTHR11481:SF93 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=8781|UniProtKB=Q07343 Q07343 PDE4B PTHR11347:SF108 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion channel binding#GO:0044325;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;protein binding#GO:0005515;phosphoric diester hydrolase activity#GO:0008081;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 HUMAN|HGNC=17787|UniProtKB=O14910 O14910 LIN7A PTHR14063:SF4 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG A protein binding#GO:0005515;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;establishment or maintenance of bipolar cell polarity#GO:0061245;export from cell#GO:0140352 membrane protein complex#GO:0098796;synapse#GO:0045202;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070 HUMAN|HGNC=3119|UniProtKB=Q15329 Q15329 E2F5 PTHR12081:SF35 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=23783|UniProtKB=Q8TCN5 Q8TCN5 ZNF507 PTHR24403:SF74 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 507 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3147|UniProtKB=O95672 O95672 ECEL1 PTHR11733:SF195 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED ENDOTHELIN-CONVERTING ENZYME-LIKE 1 metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 HUMAN|HGNC=27088|UniProtKB=A6NCI4 A6NCI4 VWA3A PTHR46478:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3A HUMAN|HGNC=591|UniProtKB=Q13489 Q13489 BIRC3 PTHR10044:SF79 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 3 cysteine-type peptidase activity#GO:0008234;peptidase inhibitor activity#GO:0030414;ubiquitin-protein transferase activity#GO:0004842;protease binding#GO:0002020;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;transferase activity#GO:0016740;cysteine-type endopeptidase activity#GO:0004197;ubiquitin protein ligase activity#GO:0061630;hydrolase activity#GO:0016787;ubiquitin-like protein ligase activity#GO:0061659;cysteine-type endopeptidase inhibitor activity#GO:0004869;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;spindle organization#GO:0007051;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;negative regulation of endopeptidase activity#GO:0010951;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043154;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;mitotic spindle organization#GO:0007052;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;protein processing#GO:0016485;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;mitotic spindle assembly#GO:0090307;cell death#GO:0008219;mitotic nuclear division#GO:0140014;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;microtubule-based process#GO:0007017;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell cycle#GO:0007049;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 protease inhibitor#PC00191 Apoptosis signaling pathway#P00006>c-IAP1,2#P00264;CCKR signaling map#P06959>BIRC3#G07286 HUMAN|HGNC=30131|UniProtKB=Q6ZVX9 Q6ZVX9 PAQR9 PTHR20855:SF58 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR EPSILON signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 G-protein coupled receptor#PC00021 HUMAN|HGNC=32434|UniProtKB=A6NNN8 A6NNN8 SLC38A8 PTHR22950:SF226 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 8-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 amino acid transporter#PC00046 HUMAN|HGNC=33630|UniProtKB=C9JE40 C9JE40 PATL2 PTHR21551:SF3 TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1 PROTEIN PAT1 HOMOLOG 2 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;deadenylation-dependent decapping of nuclear-transcribed mRNA#GO:0000290;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cytoplasmic mRNA processing body assembly#GO:0033962;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147 HUMAN|HGNC=31108|UniProtKB=P60606 P60606 CTXN1 PTHR16736:SF3 CORTEXIN-1-RELATED CORTEXIN-1 HUMAN|HGNC=5284|UniProtKB=P15516 P15516 HTN3 PTHR15057:SF0 STATHERIN HISTATIN-3 HUMAN|HGNC=1352|UniProtKB=P07357 P07357 C8A PTHR45742:SF1 COMPLEMENT COMPONENT C6 COMPLEMENT COMPONENT C8 ALPHA CHAIN HUMAN|HGNC=19339|UniProtKB=Q9NSY0 Q9NSY0 NRBP2 PTHR13902:SF53 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;protein phosphorylation#GO:0006468;cell communication#GO:0007154;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=17012|UniProtKB=O95684 O95684 CEP43 PTHR15431:SF9 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 43 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=10468|UniProtKB=O75298 O75298 RTN2 PTHR45799:SF3 RETICULON-LIKE PROTEIN RETICULON-2 HUMAN|HGNC=568|UniProtKB=O14617 O14617 AP3D1 PTHR22781:SF12 DELTA ADAPTIN-RELATED AP-3 COMPLEX SUBUNIT DELTA-1 cellular localization#GO:0051641;establishment of protein localization to vacuole#GO:0072666;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;cellular protein localization#GO:0034613;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;AP-type membrane coat adaptor complex#GO:0030119;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=29154|UniProtKB=Q9Y2F5 Q9Y2F5 ICE1 PTHR11852:SF4 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE LITTLE ELONGATION COMPLEX SUBUNIT 1 protein modifying enzyme#PC00260 HUMAN|HGNC=3770|UniProtKB=Q99518 Q99518 FMO2 PTHR23023:SF84 DIMETHYLANILINE MONOOXYGENASE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 oxygenase#PC00177 HUMAN|HGNC=18237|UniProtKB=Q8TCZ2 Q8TCZ2 CD99L2 PTHR15076:SF12 CD99/MIC2 PROTEIN RELATED CD99 ANTIGEN-LIKE PROTEIN 2 regulation of locomotion#GO:0040012;biological adhesion#GO:0022610;regulation of localization#GO:0032879;homotypic cell-cell adhesion#GO:0034109;positive regulation of cellular component movement#GO:0051272;positive regulation of leukocyte migration#GO:0002687;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;granulocyte migration#GO:0097530;regulation of cell migration#GO:0030334;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;myeloid leukocyte migration#GO:0097529;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;neutrophil migration#GO:1990266;localization of cell#GO:0051674;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;immune system process#GO:0002376;positive regulation of cell migration#GO:0030335;lymphocyte migration#GO:0072676;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=28959|UniProtKB=Q14008 Q14008 CKAP5 PTHR12609:SF0 MICROTUBULE ASSOCIATED PROTEIN XMAP215 CYTOSKELETON-ASSOCIATED PROTEIN 5 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;protein binding#GO:0005515;microtubule binding#GO:0008017;catalytic activity, acting on a protein#GO:0140096 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;microtubule organizing center organization#GO:0031023;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;protein polymerization#GO:0051258;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;protein-containing complex subunit organization#GO:0043933 supramolecular complex#GO:0099080;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;kinetochore#GO:0000776;chromosome, centromeric region#GO:0000775;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=14509|UniProtKB=Q9Y3D9 Q9Y3D9 MRPS23 PTHR15925:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S23 28S RIBOSOMAL PROTEIN S23, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ribosomal protein#PC00202 HUMAN|HGNC=29889|UniProtKB=Q7RTR2 Q7RTR2 NLRC3 PTHR24106:SF275 NACHT, LRR AND CARD DOMAINS-CONTAINING NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 3 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;negative regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043124;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;negative regulation of response to stimulus#GO:0048585;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3066|UniProtKB=O75319 O75319 DUSP11 PTHR10367:SF18 MRNA-CAPPING ENZYME RNA/RNP COMPLEX-1-INTERACTING PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 mRNA capping factor#PC00145 HUMAN|HGNC=32255|UniProtKB=A6NKC0 A6NKC0 FAM90A7P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=28646|UniProtKB=Q8IY84 Q8IY84 NIM1K PTHR24343:SF0 SERINE/THREONINE KINASE SERINE/THREONINE-PROTEIN KINASE NIM1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=3129|UniProtKB=Q14213 Q14213 EBI3 PTHR23036:SF167 CYTOKINE RECEPTOR INTERLEUKIN-27 SUBUNIT BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|Ensembl=ENSG00000282122|UniProtKB=A0A0J9YVY3 A0A0J9YVY3 IGHV7-4-1 PTHR23266:SF343 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 7-4-1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=13931|UniProtKB=Q8NDX9 Q8NDX9 LY6G5B PTHR14313:SF2 LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G5B LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G5B external side of plasma membrane#GO:0009897;leaflet of membrane bilayer#GO:0097478;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=7207|UniProtKB=O75352 O75352 MPDU1 PTHR12226:SF2 MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN HUMAN|HGNC=16683|UniProtKB=Q6GQQ9 Q6GQQ9 OTUD7B PTHR13367:SF8 UBIQUITIN THIOESTERASE OTU DOMAIN-CONTAINING PROTEIN 7B thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein K63-linked deubiquitination#GO:0070536;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein K48-linked deubiquitination#GO:0071108;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=29786|UniProtKB=Q9NYZ2 Q9NYZ2 SLC25A37 PTHR45758:SF17 MITOFERRIN-1-RELATED MITOFERRIN-1 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;iron ion transmembrane transporter activity#GO:0005381;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;iron ion transmembrane transport#GO:0034755;mitochondrial transport#GO:0006839;localization#GO:0051179;establishment of localization#GO:0051234;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;mitochondrial transmembrane transport#GO:1990542 HUMAN|HGNC=21628|UniProtKB=Q14592 Q14592 ZNF460 PTHR24384:SF15 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 460 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=25964|UniProtKB=Q9H6L5 Q9H6L5 RETREG1 PTHR28659:SF3 FAMILY NOT NAMED RETICULOPHAGY REGULATOR 1 neuron apoptotic process#GO:0051402;negative regulation of biological process#GO:0048519;endoplasmic reticulum organization#GO:0007029;macroautophagy#GO:0016236;regulation of neuron death#GO:1901214;endomembrane system organization#GO:0010256;neuron death#GO:0070997;negative regulation of neuron death#GO:1901215;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;programmed cell death#GO:0012501;cellular process#GO:0009987;organelle disassembly#GO:1903008;negative regulation of apoptotic process#GO:0043066;negative regulation of cell death#GO:0060548;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of cell death#GO:0010941;biological regulation#GO:0065007;autophagy#GO:0006914 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=6149|UniProtKB=P11215 P11215 ITGAM PTHR23220:SF130 INTEGRIN ALPHA INTEGRIN ALPHA-M integrin#PC00126 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=17034|UniProtKB=O75896 O75896 TUSC2 PTHR15453:SF8 TUMOR SUPPRESSOR CANDIDATE 2 TUMOR SUPPRESSOR CANDIDATE 2 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=22431|UniProtKB=Q5HYL7 Q5HYL7 TMEM196 PTHR28681:SF1 TRANSMEMBRANE PROTEIN 196 TRANSMEMBRANE PROTEIN 196 HUMAN|HGNC=11695|UniProtKB=Q8IZS6 Q8IZS6 TCTE3 PTHR21255:SF27 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN TCTEX1 DOMAIN-CONTAINING PROTEIN 3 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=30899|UniProtKB=Q8N720 Q8N720 ZNF655 PTHR24377:SF284 IP01015P-RELATED ZINC FINGER PROTEIN 655 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=427|UniProtKB=Q9UM73 Q9UM73 ALK PTHR24416:SF276 TYROSINE-PROTEIN KINASE RECEPTOR ALK TYROSINE KINASE RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;neurogenesis#GO:0022008;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell population proliferation#GO:0008283;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=17598|UniProtKB=Q9Y385 Q9Y385 UBE2J1 PTHR24068:SF168 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=856|UniProtKB=P21283 P21283 ATP6V1C1 PTHR10137:SF5 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002 HUMAN|HGNC=14816|UniProtKB=Q8NGX3 Q8NGX3 OR10T2 PTHR26451:SF98 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10T2 HUMAN|HGNC=19769|UniProtKB=Q8WXJ9 Q8WXJ9 ASB17 PTHR20966:SF2 ANKYRIN REPEAT AND SOCS BOX PROTEIN 17 ANKYRIN REPEAT AND SOCS BOX PROTEIN 17 HUMAN|HGNC=15721|UniProtKB=Q9NRL3 Q9NRL3 STRN4 PTHR15653:SF1 STRIATIN STRIATIN-4 phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein-containing complex binding#GO:0044877;protein phosphatase binding#GO:0019903;binding#GO:0005488 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;plasma membrane region#GO:0098590;dendrite#GO:0030425;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=1535|UniProtKB=Q06455 Q06455 RUNX1T1 PTHR10379:SF5 MTG8 ETO EIGHT TWENTY ONE PROTEIN PROTEIN CBFA2T1 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=7952|UniProtKB=Q15818 Q15818 NPTX1 PTHR19277:SF24 PENTRAXIN NEURONAL PENTRAXIN-1 HUMAN|HGNC=24301|UniProtKB=Q9NPA0 Q9NPA0 EMC7 PTHR13605:SF4 UNCHARACTERIZED ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7 membrane protein complex#GO:0098796;ER membrane protein complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=14953|UniProtKB=Q9NXH3 Q9NXH3 PPP1R14D PTHR16188:SF13 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14D phosphatase binding#GO:0019902;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096;protein phosphatase inhibitor activity#GO:0004864 phosphatase modulator#PC00184 HUMAN|HGNC=25550|UniProtKB=Q96TC7 Q96TC7 RMDN3 PTHR16056:SF18 UNCHARACTERIZED REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 3 HUMAN|HGNC=1037|UniProtKB=P00751 P00751 CFB PTHR46393:SF1 SUSHI DOMAIN-CONTAINING PROTEIN COMPLEMENT FACTOR B HUMAN|HGNC=25313|UniProtKB=Q9H0I9 Q9H0I9 TKTL2 PTHR43195:SF4 TRANSKETOLASE TRANSKETOLASE-LIKE PROTEIN 2 cation binding#GO:0043169;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 transketolase#PC00221 HUMAN|HGNC=9395|UniProtKB=P05771 P05771 PRKCB PTHR24356:SF158 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C BETA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>PKCbeta#P07177;EGF receptor signaling pathway#P00018>PKC#P00565;Metabotropic glutamate receptor group I pathway#P00041>PKC#P01055;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Apoptosis signaling pathway#P00006>PKCs#P00318;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861;B cell activation#P00010>PKC#P00373;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 HUMAN|HGNC=24888|UniProtKB=Q7Z6Z6 Q7Z6Z6 PNPLA5 PTHR12406:SF4 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 5 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid catabolic process#GO:0046461;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;chemical homeostasis#GO:0048878;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 phospholipase#PC00186 HUMAN|HGNC=11958|UniProtKB=Q96L91 Q96L91 EP400 PTHR46459:SF2 E1A-BINDING PROTEIN P400-RELATED E1A-BINDING PROTEIN P400-RELATED Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=3757|UniProtKB=O75955 O75955 FLOT1 PTHR13806:SF16 FLOTILLIN-RELATED FLOTILLIN-1 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;regulation of cell-cell adhesion#GO:0022407;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;regulation of endocytosis#GO:0030100;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;positive regulation of transport#GO:0051050;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular component organization#GO:0016043;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;regulation of receptor-mediated endocytosis#GO:0048259;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;receptor internalization#GO:0031623;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;biological adhesion#GO:0022610;transport#GO:0006810;regulation of transport#GO:0051049;cell junction assembly#GO:0034329;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell adhesion#GO:0030155;signaling#GO:0023052;metabolic process#GO:0008152;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;protein localization to membrane#GO:0072657;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;protein localization to cell periphery#GO:1990778;localization#GO:0051179;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;cell junction organization#GO:0034330;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;regulation of cell junction assembly#GO:1901888;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 plasma membrane raft#GO:0044853;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;membrane raft#GO:0045121;membrane region#GO:0098589;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 HUMAN|HGNC=3277|UniProtKB=P60228 P60228 EIF3E PTHR10317:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 translation initiation factor#PC00224 HUMAN|HGNC=20696|UniProtKB=Q9H9T3 Q9H9T3 ELP3 PTHR11135:SF0 HISTONE ACETYLTRANSFERASE-RELATED ELONGATOR COMPLEX PROTEIN 3 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=29230|UniProtKB=Q9ULI0 Q9ULI0 ATAD2B PTHR23069:SF5 AAA DOMAIN-CONTAINING ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2B pyrophosphatase activity#GO:0016462;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;histone binding#GO:0042393;ATPase activity#GO:0016887 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of chromatin silencing#GO:0031935;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of chromatin silencing#GO:0031936;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of chromatin organization#GO:1902275;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=14645|UniProtKB=Q9H8X2 Q9H8X2 IPPK PTHR14456:SF2 INOSITOL POLYPHOSPHATE KINASE 1 INOSITOL-PENTAKISPHOSPHATE 2-KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular carbohydrate metabolic process#GO:0044262;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;small molecule biosynthetic process#GO:0044283;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 kinase#PC00137 HUMAN|HGNC=24108|UniProtKB=Q7Z591 Q7Z591 AKNA PTHR21510:SF15 FAMILY NOT NAMED MICROTUBULE ORGANIZATION PROTEIN AKNA HUMAN|HGNC=6808|UniProtKB=P43366 P43366 MAGEB1 PTHR11736:SF140 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15512|UniProtKB=Q8TAA9 Q8TAA9 VANGL1 PTHR20886:SF8 VANG-LIKE PROTEIN VANG-LIKE PROTEIN 1 signal transduction#GO:0007165;regulation of anatomical structure morphogenesis#GO:0022603;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;non-canonical Wnt signaling pathway#GO:0035567;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;establishment of planar polarity#GO:0001736;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;tissue development#GO:0009888;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;biological regulation#GO:0065007;morphogenesis of an epithelium#GO:0002009;multicellular organismal process#GO:0032501 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=20392|UniProtKB=Q8IWU5 Q8IWU5 SULF2 PTHR43108:SF4 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;catalytic activity#GO:0003824 positive regulation of gene expression#GO:0010628;positive regulation of signal transduction#GO:0009967;negative regulation of cellular response to growth factor stimulus#GO:0090288;gene expression#GO:0010467;kidney development#GO:0001822;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;positive regulation of cytokine production#GO:0001819;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;fibroblast growth factor receptor signaling pathway#GO:0008543;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;carbohydrate derivative metabolic process#GO:1901135;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of Wnt signaling pathway#GO:0030177;cytokine production#GO:0001816;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;urogenital system development#GO:0001655;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;response to stimulus#GO:0050896;heparan sulfate proteoglycan metabolic process#GO:0030201;extracellular structure organization#GO:0043062;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;cell surface#GO:0009986;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 hydrolase#PC00121 HUMAN|HGNC=21245|UniProtKB=Q6UXB8 Q6UXB8 PI16 PTHR10334:SF461 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 16 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=31446|UniProtKB=Q8NCN2 Q8NCN2 ZBTB34 PTHR24399:SF42 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 34 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=22990|UniProtKB=Q86Y22 Q86Y22 COL23A1 PTHR24023:SF995 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXIII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=21606|UniProtKB=Q9Y5U8 Q9Y5U8 MPC1 PTHR14154:SF8 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 1 HUMAN|HGNC=3756|UniProtKB=Q14315 Q14315 FLNC PTHR38537:SF12 JITTERBUG, ISOFORM N FILAMIN-C HUMAN|HGNC=30325|UniProtKB=Q9H477 Q9H477 RBKS PTHR10584:SF166 SUGAR KINASE RIBOKINASE carbohydrate kinase#PC00065 HUMAN|HGNC=25572|UniProtKB=Q8N5G2 Q8N5G2 MACO1 PTHR13289:SF6 PROTEIN PHOSPHATASE 1-BINDING PROTEIN BIFOCAL MACOILIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;microtubule binding#GO:0008017;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 regulation of biological process#GO:0050789;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;locomotion#GO:0040011;signaling#GO:0023052;chemotaxis#GO:0006935;taxis#GO:0042330 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;rough endoplasmic reticulum membrane#GO:0030867;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227 HUMAN|HGNC=24811|UniProtKB=Q14554 Q14554 PDIA5 PTHR45672:SF2 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED PROTEIN DISULFIDE-ISOMERASE A5 chaperone#PC00072 HUMAN|HGNC=25357|UniProtKB=Q8N1N0 Q8N1N0 CLEC4F PTHR22802:SF238 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER F membrane traffic protein#PC00150 HUMAN|HGNC=24258|UniProtKB=Q96E29 Q96E29 MTERF3 PTHR13068:SF194 CGI-12 PROTEIN-RELATED TRANSCRIPTION TERMINATION FACTOR 3, MITOCHONDRIAL organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17572|UniProtKB=Q9UM22 Q9UM22 EPDR1 PTHR10697:SF1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 MAMMALIAN EPENDYMIN-RELATED PROTEIN 1 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=21265|UniProtKB=Q9NZP8 Q9NZP8 C1RL PTHR24255:SF26 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1R SUBCOMPONENT-LIKE PROTEIN serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;protein metabolic process#GO:0019538;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=37098|UniProtKB=B2RXH2 B2RXH2 KDM4E PTHR10694:SF34 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4E 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=10614|UniProtKB=O15467 O15467 CCL16 PTHR12015:SF21 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 16 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=703|UniProtKB=Q92747 Q92747 ARPC1A PTHR10709:SF11 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1A cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Huntington disease#P00029>Arp2/3 complex#P00811 HUMAN|HGNC=29219|UniProtKB=Q6ZU35 Q6ZU35 CRACD PTHR47574:SF3 CANCER-RELATED REGULATOR OF ACTIN DYNAMICS CAPPING PROTEIN INHIBITING REGULATOR OF ACTIN DYNAMICS HUMAN|HGNC=25363|UniProtKB=Q9H0R3 Q9H0R3 TMEM222 PTHR20921:SF0 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 222 HUMAN|HGNC=11107|UniProtKB=Q92925 Q92925 SMARCD2 PTHR13844:SF2 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 2 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;protein-containing complex disassembly#GO:0032984;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=17080|UniProtKB=Q5H9B9 Q5H9B9 BMP2KL PTHR22967:SF96 SERINE/THREONINE PROTEIN KINASE AP2-ASSOCIATED PROTEIN KINASE 1-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;membrane organization#GO:0061024;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of Notch signaling pathway#GO:0008593;phosphorus metabolic process#GO:0006793;regulation of vesicle-mediated transport#GO:0060627;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of transport#GO:0051049;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of endocytosis#GO:0030100;cellular response to stimulus#GO:0051716;clathrin-dependent endocytosis#GO:0072583;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;localization#GO:0051179;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of receptor-mediated endocytosis#GO:0048259;Notch signaling pathway#GO:0007219 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=2494|UniProtKB=Q13363 Q13363 CTBP1 PTHR46029:SF2 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN 1 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 HUMAN|HGNC=13058|UniProtKB=O95218 O95218 ZRANB2 PTHR12999:SF17 ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 RNA splicing factor#PC00148 HUMAN|HGNC=2498|UniProtKB=Q9Y5B0 Q9Y5B0 CTDP1 PTHR23081:SF0 RNA POLYMERASE II CTD PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;dephosphorylation#GO:0016311;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein phosphatase#PC00195 General transcription regulation#P00023>TFIIF#P00665;Transcription regulation by bZIP transcription factor#P00055>TFIIF#P01394 HUMAN|HGNC=18270|UniProtKB=Q5VTY9 Q5VTY9 HHAT PTHR13285:SF20 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE HHAT transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=172|UniProtKB=P36896 P36896 ACVR1B PTHR23255:SF22 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1B signaling receptor activity#GO:0038023;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;activin binding#GO:0048185;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;Gonadotropin-releasing hormone receptor pathway#P06664>Alk4#P06845 HUMAN|HGNC=461|UniProtKB=Q99217 Q99217 AMELX PTHR46794:SF2 AMELOGENIN, Y ISOFORM AMELOGENIN, X ISOFORM HUMAN|HGNC=1380|UniProtKB=P23280 P23280 CA6 PTHR18952:SF110 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 6 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 HUMAN|HGNC=13071|UniProtKB=Q9HBE1 Q9HBE1 PATZ1 PTHR24399:SF15 ZINC FINGER AND BTB DOMAIN-CONTAINING POZ-, AT HOOK-, AND ZINC FINGER-CONTAINING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=728|UniProtKB=O00192 O00192 ARVCF PTHR10372:SF5 PLAKOPHILLIN-RELATED ARMADILLO REPEAT PROTEIN DELETED IN VELO-CARDIO-FACIAL SYNDROME cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130 HUMAN|HGNC=6552|UniProtKB=O75610 O75610 LEFTY1 PTHR11848:SF257 TGF-BETA FAMILY LEFT-RIGHT DETERMINATION FACTOR 1 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=17500|UniProtKB=Q9H8Y8 Q9H8Y8 GORASP2 PTHR12893:SF1 GOLGI REASSEMBLY STACKING PROTEIN GRASP GOLGI REASSEMBLY-STACKING PROTEIN 2 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=26464|UniProtKB=Q8IZ41 Q8IZ41 RASEF PTHR22621:SF6 UNCHARACTERIZED RAS AND EF-HAND DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=36404|UniProtKB=Q8NHW5 Q8NHW5 RPLP0P6 PTHR45699:SF1 60S ACIDIC RIBOSOMAL PROTEIN P0 60S ACIDIC RIBOSOMAL PROTEIN P0-RELATED structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=12214|UniProtKB=A0A0K0K1B3 A0A0K0K1B3 TRBV30 PTHR23268:SF31 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 30 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=6636|UniProtKB=P02545 P02545 LMNA PTHR45721:SF5 LAMIN DM0-RELATED PRELAMIN-A/C FAS signaling pathway#P00020>Nuclear Lamin#P00616 HUMAN|HGNC=18923|UniProtKB=Q52LG2 Q52LG2 KRTAP13-2 PTHR19051:SF29 KERATIN-ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 13-2 structural protein#PC00211 HUMAN|HGNC=4326|UniProtKB=P23415 P23415 GLRA1 PTHR18945:SF213 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;transport#GO:0006810;system process#GO:0003008;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;regulation of biological process#GO:0050789;inorganic anion transmembrane transport#GO:0098661;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;signaling#GO:0023052;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=13403|UniProtKB=Q9BYU1 Q9BYU1 PBX4 PTHR11850:SF98 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;sensory system development#GO:0048880;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;neuron development#GO:0048666;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;visual system development#GO:0150063;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=3123|UniProtKB=O00559 O00559 EBAG9 PTHR15208:SF2 RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS CANCER ASSOCIATED SURFACE ANTIGEN RCAS1 ESTROGEN RECEPTOR-BINDING FRAGMENT- ASSOCIATED GENE 9 PROTEIN RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=12705|UniProtKB=O95497 O95497 VNN1 PTHR10609:SF16 BIOTINIDASE-RELATED PANTETHEINASE hydrolase#PC00121 HUMAN|HGNC=22963|UniProtKB=O75448 O75448 MED24 PTHR12898:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=9243|UniProtKB=O14829 O14829 PPEF1 PTHR45668:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 HUMAN|HGNC=12326|UniProtKB=Q12816 Q12816 TRO PTHR11736:SF83 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN TROPHININ scaffold/adaptor protein#PC00226 HUMAN|HGNC=9523|UniProtKB=Q00889 Q00889 PSG6 PTHR44427:SF17 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 4-RELATED HUMAN|Gene=LPPR3|UniProtKB=Q6T4P5 Q6T4P5 PLPPR3 PTHR10165:SF14 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphatase#PC00181 HUMAN|HGNC=11733|UniProtKB=Q8IYF3 Q8IYF3 TEX11 PTHR47083:SF1 TESTIS-EXPRESSED PROTEIN 11 TESTIS-EXPRESSED PROTEIN 11 HUMAN|HGNC=31865|UniProtKB=Q9H903 Q9H903 MTHFD2L PTHR48099:SF7 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;pteridine-containing compound metabolic process#GO:0042558;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Formyltetrahydroformate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 HUMAN|HGNC=19632|UniProtKB=Q8NGE1 Q8NGE1 OR6C4 PTHR26454:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=6619|UniProtKB=P11150 P11150 LIPC PTHR11610:SF2 LIPASE HEPATIC TRIACYLGLYCEROL LIPASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;phospholipase activity#GO:0004620;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid catabolic process#GO:0044242;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;triglyceride metabolic process#GO:0006641;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerolipid catabolic process#GO:0046503;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143 Triacylglycerol metabolism#P02782>Triacylglycerol lipase#P03205 HUMAN|HGNC=30594|UniProtKB=Q9H3U1 Q9H3U1 UNC45A PTHR45994:SF3 FI21225P1 PROTEIN UNC-45 HOMOLOG A heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488;Hsp90 protein binding#GO:0051879 chaperone-mediated protein folding#GO:0061077;cellular process#GO:0009987;protein folding#GO:0006457 HUMAN|HGNC=18584|UniProtKB=Q8IU57 Q8IU57 IFNLR1 PTHR20859:SF55 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON LAMBDA RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=25585|UniProtKB=Q8N543 Q8N543 OGFOD1 PTHR12117:SF0 HISTONE ACETYLTRANSFERASE COMPLEX PROLYL 3-HYDROXYLASE OGFOD1 histone modifying enzyme#PC00261 HUMAN|HGNC=26272|UniProtKB=Q6NSJ5 Q6NSJ5 LRRC8E PTHR45752:SF8 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8E hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 scaffold/adaptor protein#PC00226 HUMAN|HGNC=19159|UniProtKB=Q96GR4 Q96GR4 ZDHHC12 PTHR22883:SF301 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC12-RELATED transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=34495|UniProtKB=Q86XI8 Q86XI8 ZSWIM9 PTHR47086:SF1 BTB DOMAIN-CONTAINING PROTEIN SWIM-TYPE DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=25341|UniProtKB=Q6ZWK4 Q6ZWK4 RHEX PTHR38491:SF1 REGULATOR OF HEMOGLOBINIZATION AND ERYTHROID CELL EXPANSION PROTEIN REGULATOR OF HEMOGLOBINIZATION AND ERYTHROID CELL EXPANSION PROTEIN HUMAN|HGNC=23298|UniProtKB=O95858 O95858 TSPAN15 PTHR19282:SF159 TETRASPANIN TETRASPANIN-15 protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=17660|UniProtKB=Q6PJP8 Q6PJP8 DCLRE1A PTHR23240:SF6 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED DNA CROSS-LINK REPAIR 1A PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;damaged DNA binding#GO:0003684;exonuclease activity#GO:0004527;deoxyribonuclease activity#GO:0004536;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;exodeoxyribonuclease activity#GO:0004529;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;exodeoxyribonuclease activity, producing 5'-phosphomonoesters#GO:0016895 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;telomere capping#GO:0016233;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;chromosome organization#GO:0051276;organelle organization#GO:0006996;biological regulation#GO:0065007;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009 HUMAN|HGNC=4634|UniProtKB=P28161 P28161 GSTM2 PTHR11571:SF254 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 2 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=23384|UniProtKB=Q8TF39 Q8TF39 ZNF483 PTHR24377:SF425 IP01015P-RELATED ZINC FINGER PROTEIN 483 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2548|UniProtKB=O60494 O60494 CUBN PTHR47537:SF2 CUBILIN CUBILIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=8234|UniProtKB=Q96R45 Q96R45 OR2A7 PTHR26451:SF971 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 2A4-RELATED HUMAN|HGNC=9922|UniProtKB=P02753 P02753 RBP4 PTHR11873:SF2 RETINOL-BINDING PROTEIN 4 RETINOL-BINDING PROTEIN 4 lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 HUMAN|HGNC=26636|UniProtKB=Q8NAP3 Q8NAP3 ZBTB38 PTHR24388:SF71 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 38 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=380|UniProtKB=P14550 P14550 AKR1A1 PTHR11732:SF421 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER A1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=684|UniProtKB=Q9NR80 Q9NR80 ARHGEF4 PTHR47544:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=8293|UniProtKB=Q15615 Q15615 OR4D1 PTHR48002:SF15 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D1 transmembrane signal receptor#PC00197 HUMAN|HGNC=8033|UniProtKB=Q16288 Q16288 NTRK3 PTHR24416:SF66 TYROSINE-PROTEIN KINASE RECEPTOR NT-3 GROWTH FACTOR RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to growth factor#GO:0070848;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein kinase B signaling#GO:0043491;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of protein kinase B signaling#GO:0051896;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=7200|UniProtKB=Q9HCE1 Q9HCE1 MOV10 PTHR10887:SF322 DNA2/NAM7 HELICASE FAMILY HELICASE MOV-10 posttranscriptional regulation of gene expression#GO:0010608;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;negative regulation of metabolic process#GO:0009892;gene silencing by RNA#GO:0031047;cellular process#GO:0009987;post-transcriptional gene silencing by RNA#GO:0035194;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;posttranscriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;gene silencing#GO:0016458;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;regulation of gene expression, epigenetic#GO:0040029;metabolic process#GO:0008152 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=14914|UniProtKB=Q8N1Q1 Q8N1Q1 CA13 PTHR18952:SF81 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 13 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=44405|UniProtKB=F8WBI6 F8WBI6 GOLGA8N PTHR10881:SF62 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8H-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=22197|UniProtKB=O43299 O43299 AP5Z1 PTHR46488:SF1 AP-5 COMPLEX SUBUNIT ZETA-1 AP-5 COMPLEX SUBUNIT ZETA-1 HUMAN|HGNC=16746|UniProtKB=Q5VZF2 Q5VZF2 MBNL2 PTHR12675:SF4 MUSCLEBLIND-LIKE PROTEIN MUSCLEBLIND-LIKE PROTEIN 2 RNA splicing factor#PC00148 HUMAN|HGNC=19007|UniProtKB=Q8NE63 Q8NE63 HIPK4 PTHR24058:SF46 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 4 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28517|UniProtKB=Q8NBL3 Q8NBL3 TMEM178A PTHR32005:SF4 TRANSMEMBRANE PROTEIN 178B-RELATED TRANSMEMBRANE PROTEIN 178A cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;animal organ development#GO:0048513;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;regulation of multicellular organismal development#GO:2000026;cellular homeostasis#GO:0019725;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;osteoclast differentiation#GO:0030316;system development#GO:0048731;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;regulation of hemopoiesis#GO:1903706;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;cellular divalent inorganic cation homeostasis#GO:0072503;negative regulation of cellular process#GO:0048523;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;cellular cation homeostasis#GO:0030003;regulation of multicellular organismal process#GO:0051239;immune system development#GO:0002520;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;immune system process#GO:0002376;leukocyte differentiation#GO:0002521;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=2051|UniProtKB=O95484 O95484 CLDN9 PTHR12002:SF42 CLAUDIN CLAUDIN-9 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=30843|UniProtKB=Q8IX05 Q8IX05 CD302 PTHR22803:SF144 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED CD302 ANTIGEN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 HUMAN|HGNC=16170|UniProtKB=Q9NTX9 Q9NTX9 FAM217B PTHR22145:SF3 SI:CH211-266K22.6 PROTEIN FAM217B HUMAN|HGNC=20664|UniProtKB=Q71UI9 Q71UI9 H2AZ2 PTHR23430:SF280 HISTONE H2A HISTONE H2A.V heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=1673|UniProtKB=P04234 P04234 CD3D PTHR10570:SF5 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 DELTA CHAIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;lymphocyte activation#GO:0046649;immune system development#GO:0002520;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;hematopoietic or lymphoid organ development#GO:0048534;cell communication#GO:0007154;cellular process#GO:0009987;T cell differentiation#GO:0030217;cell activation#GO:0001775;regulation of biological process#GO:0050789;immune system process#GO:0002376;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;lymphocyte differentiation#GO:0030098;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;signaling#GO:0023052;leukocyte activation#GO:0045321 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 T cell activation#P00053>CD3 delta#P01326 HUMAN|HGNC=29025|UniProtKB=O15090 O15090 ZNF536 PTHR45925:SF2 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 536 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=24101|UniProtKB=Q9BXP5 Q9BXP5 SRRT PTHR13165:SF0 ARSENITE-RESISTANCE PROTEIN 2 SERRATE RNA EFFECTOR MOLECULE HOMOLOG negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression#GO:0010468;regulation of gene expression, epigenetic#GO:0040029;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;gene silencing by miRNA#GO:0035195;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;gene silencing by RNA#GO:0031047;cellular process#GO:0009987;primary metabolic process#GO:0044238;production of miRNAs involved in gene silencing by miRNA#GO:0035196;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;posttranscriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 HUMAN|HGNC=5132|UniProtKB=Q9GZZ0 Q9GZZ0 HOXD1 PTHR45946:SF1 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-D1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=17299|UniProtKB=Q6XPS3 Q6XPS3 TPTE2 PTHR12305:SF60 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE TPTE2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 p53 pathway#P00059>PTEN#G01579;p53 pathway feedback loops 2#P04398>PTEN#G04714;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway#P00059>PTEN#P01480;Hypoxia response via HIF activation#P00030>PTEN#P00824;PI3 kinase pathway#P00048>PTEN#P01189;p53 pathway feedback loops 2#P04398>PTEN#P04658 HUMAN|HGNC=12620|UniProtKB=Q9UK80 Q9UK80 USP21 PTHR21646:SF6 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=4215|UniProtKB=P55107 P55107 GDF10 PTHR11848:SF145 TGF-BETA FAMILY GROWTH/DIFFERENTIATION FACTOR 10 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=13782|UniProtKB=Q9HCQ7 Q9HCQ7 NPVF PTHR14403:SF6 RFAMIDE PEPTIDE GONADOTROPIN INHIBITORY HORMONE PRO-FMRFAMIDE-RELATED NEUROPEPTIDE VF protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;transport#GO:0006810;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of system process#GO:0044057;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;hormone secretion#GO:0046879;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of secretion#GO:0051046;neuropeptide signaling pathway#GO:0007218;regulation of hormone secretion#GO:0046883;signal release#GO:0023061;hormone transport#GO:0009914;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;negative regulation of transport#GO:0051051;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;export from cell#GO:0140352 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>RFRP-1/-3#P06828 HUMAN|HGNC=14687|UniProtKB=Q9Y5Y7 Q9Y5Y7 LYVE1 PTHR10225:SF2 HYALURONAN RECEPTOR LYMPHATIC VESSEL ENDOTHELIAL HYALURONIC ACID RECEPTOR 1 carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;glycosaminoglycan binding#GO:0005539;transmembrane signaling receptor activity#GO:0004888 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=28324|UniProtKB=Q96BF3 Q96BF3 TMIGD2 PTHR23267:SF349 IMMUNOGLOBULIN LIGHT CHAIN TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=29264|UniProtKB=Q9P2H0 Q9P2H0 CEP126 PTHR31191:SF4 CENTROSOMAL PROTEIN CEP126 CENTROSOMAL PROTEIN OF 126 KDA vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cytoplasmic microtubule organization#GO:0031122;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 DNA metabolism protein#PC00009 HUMAN|HGNC=13630|UniProtKB=P0C1Z6 P0C1Z6 TFPT PTHR35084:SF1 TCF3 FUSION PARTNER TCF3 FUSION PARTNER nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067 Ino80 complex#GO:0031011;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 HUMAN|HGNC=27302|UniProtKB=Q5T440 Q5T440 IBA57 PTHR22602:SF0 UNCHARACTERIZED TRANSFERASE CAF17, MITOCHONDRIAL-RELATED HUMAN|HGNC=956|UniProtKB=Q9UMQ3 Q9UMQ3 BARX2 PTHR24330:SF7 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN BARH-LIKE 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=7885|UniProtKB=P48745 P48745 CCN3 PTHR11348:SF8 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 3 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;biological adhesion#GO:0022610;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;regulation of cell death#GO:0010941;cell death#GO:0008219;biological regulation#GO:0065007;signaling#GO:0023052;negative regulation of cellular process#GO:0048523 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=27652|UniProtKB=Q8WVH0 Q8WVH0 CPLX3 PTHR16705:SF5 COMPLEXIN COMPLEXIN-3 protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;cell junction#GO:0030054;SNARE complex#GO:0031201;terminal bouton#GO:0043195;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=30784|UniProtKB=Q14140 Q14140 SERTAD2 PTHR16277:SF10 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 SERTA DOMAIN-CONTAINING PROTEIN 2 molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=20523|UniProtKB=P60371 P60371 KRTAP10-6 PTHR23262:SF227 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-4-RELATED HUMAN|HGNC=17995|UniProtKB=Q9BX84 Q9BX84 TRPM6 PTHR13800:SF15 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 6 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177 ion channel#PC00133 HUMAN|HGNC=28201|UniProtKB=Q5BJH2 Q5BJH2 TMEM128 PTHR31134:SF1 TRANSMEMBRANE PROTEIN 128 TRANSMEMBRANE PROTEIN 128 HUMAN|HGNC=16923|UniProtKB=Q96P47 Q96P47 AGAP3 PTHR45819:SF2 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=24836|UniProtKB=Q6ZVL6 Q6ZVL6 KIAA1549L PTHR21590:SF3 UNCHARACTERIZED UPF0606 PROTEIN KIAA1549L HUMAN|HGNC=12190|UniProtKB=A0A087WZ39 A0A087WZ39 TRBV15 PTHR23268:SF13 T-CELL RECEPTOR BETA CHAIN IGV DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=26193|UniProtKB=Q1MSJ5 Q1MSJ5 CSPP1 PTHR21616:SF2 CENTROSOME SPINDLE POLE ASSOCIATED PROTEIN CENTROSOME AND SPINDLE POLE-ASSOCIATED PROTEIN 1 centromere DNA-binding protein#PC00071 HUMAN|HGNC=14135|UniProtKB=Q9BRB3 Q9BRB3 PIGQ PTHR21329:SF3 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q-RELATED PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=8055|UniProtKB=Q8WV74 Q8WV74 NUDT8 PTHR12992:SF11 NUDIX HYDROLASE NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 8 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;heterocycle biosynthetic process#GO:0018130;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 phosphatase#PC00181 HUMAN|HGNC=5993|UniProtKB=P14778 P14778 IL1R1 PTHR11890:SF26 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR TYPE 1 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of inflammatory response#GO:0050727;response to external stimulus#GO:0009605;regulation of response to external stimulus#GO:0032101;response to stress#GO:0006950;regulation of defense response#GO:0031347;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;defense response#GO:0006952;inflammatory response#GO:0006954 transmembrane signal receptor#PC00197 p38 MAPK pathway#P05918>IL-1R#P06030 HUMAN|HGNC=30|UniProtKB=Q8WWZ4 Q8WWZ4 ABCA10 PTHR19229:SF163 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 10 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=24200|UniProtKB=Q6SJ93 Q6SJ93 FAM111B PTHR14389:SF4 SI:CH1073-475A24.1 PROTEIN FAM111B HUMAN|HGNC=7983|UniProtKB=Q13285 Q13285 NR5A1 PTHR24086:SF24 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A STEROIDOGENIC FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>SF1#P06848 HUMAN|HGNC=29992|UniProtKB=Q96GU1 Q96GU1 PAGE5 PTHR14047:SF37 P ANTIGEN FAMILY MEMBER 5-RELATED P ANTIGEN FAMILY MEMBER 5 HUMAN|HGNC=37282|UniProtKB=Q9C0K3 Q9C0K3 ACTR3C PTHR11937:SF514 ACTIN ACTIN-RELATED PROTEIN 3B-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cortical cytoskeleton#GO:0030863;Arp2/3 protein complex#GO:0005885;cortical actin cytoskeleton#GO:0030864;actin cortical patch#GO:0030479;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 HUMAN|HGNC=2363|UniProtKB=P46109 P46109 CRKL PTHR19969:SF20 SH2-SH3 ADAPTOR PROTEIN-RELATED CRK-LIKE PROTEIN scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>Crk#P00933;Angiogenesis#P00005>Crk#P00207 HUMAN|HGNC=5879|UniProtKB=P01699 P01699 IGLV1-44 PTHR23267:SF413 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 1-44-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=12805|UniProtKB=P47989 P47989 XDH PTHR11908:SF80 XANTHINE DEHYDROGENASE XANTHINE DEHYDROGENASE/OXIDASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidoreductase#PC00176 Adenine and hypoxanthine salvage pathway#P02723>Xanthine dehydrogenase#P02809;Purine metabolism#P02769>Xanthine Oxidase#P03116 HUMAN|HGNC=20648|UniProtKB=Q96HQ0 Q96HQ0 ZNF419 PTHR24377:SF633 IP01015P-RELATED ZINC FINGER PROTEIN 419 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8067|UniProtKB=Q99567 Q99567 NUP88 PTHR13257:SF0 NUCLEOPORIN NUP84-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP88 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;ribosomal subunit export from nucleus#GO:0000054;organelle localization#GO:0051640;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;ribosome biogenesis#GO:0042254;protein localization to organelle#GO:0033365;protein import#GO:0017038;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;peptide transport#GO:0015833;mRNA transport#GO:0051028;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;ribonucleoprotein complex biogenesis#GO:0022613;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170;protein-containing complex localization#GO:0031503 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=23841|UniProtKB=Q9C0E4 Q9C0E4 GRIP2 PTHR46227:SF4 GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP GLUTAMATE RECEPTOR-INTERACTING PROTEIN 2 endosomal transport#GO:0016197;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;protein localization to plasma membrane#GO:0072659;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;retrograde transport, endosome to plasma membrane#GO:1990126;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 HUMAN|HGNC=23502|UniProtKB=Q8IW52 Q8IW52 SLITRK4 PTHR45773:SF3 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 4 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;generation of neurons#GO:0048699;cell part morphogenesis#GO:0032990 HUMAN|HGNC=15716|UniProtKB=Q9Y5Z4 Q9Y5Z4 HEBP2 PTHR11220:SF70 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=23117|UniProtKB=Q6UWF7 Q6UWF7 NXPE4 PTHR16165:SF27 BRUSH BORDER-RELATED NXPE FAMILY MEMBER 4 HUMAN|HGNC=23067|UniProtKB=Q8IUR0 Q8IUR0 TRAPPC5 PTHR20902:SF0 41-2 PROTEIN ANTIGEN-RELATED TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;plasma membrane#GO:0005886 HUMAN|HGNC=8972|UniProtKB=O00750 O00750 PIK3C2B PTHR10048:SF30 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;phosphatidylinositol-mediated signaling#GO:0048015;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;phosphatidylinositol 3-kinase signaling#GO:0014065;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;inositol lipid-mediated signaling#GO:0048017;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477;locomotion#GO:0040011;phosphatidylinositol phosphorylation#GO:0046854 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 HUMAN|HGNC=31073|UniProtKB=Q9Y2K3 Q9Y2K3 MYH15 PTHR45615:SF26 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-15 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=24229|UniProtKB=Q96AQ7 Q96AQ7 CIDEC PTHR12306:SF9 CELL DEATH ACTIVATOR CIDE CELL DEATH ACTIVATOR CIDE-3 regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=18180|UniProtKB=Q9NZT1 Q9NZT1 CALML5 PTHR23050:SF224 CALCIUM BINDING PROTEIN CALMODULIN-LIKE PROTEIN 5 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 calmodulin-related#PC00061 HUMAN|HGNC=939|UniProtKB=O95817 O95817 BAG3 PTHR12329:SF12 BCL2-ASSOCIATED ATHANOGENE BAG FAMILY MOLECULAR CHAPERONE REGULATOR 3 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234;chaperone binding#GO:0051087;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;regulation of protein stability#GO:0031647;homeostatic process#GO:0042592;programmed cell death#GO:0012501;cellular homeostasis#GO:0019725;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;protein stabilization#GO:0050821;regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;anatomical structure homeostasis#GO:0060249;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 Apoptosis signaling pathway#P00006>Bag#P00278 HUMAN|HGNC=682|UniProtKB=Q92974 Q92974 ARHGEF2 PTHR13944:SF20 AGAP007712-PA RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2 Rho guanyl-nucleotide exchange factor activity#GO:0005089;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;microtubule binding#GO:0008017;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;supramolecular fiber organization#GO:0097435;neuron differentiation#GO:0030182;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of neuron differentiation#GO:0045666;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;regulation of neuron differentiation#GO:0045664;positive regulation of developmental process#GO:0051094;Rho protein signal transduction#GO:0007266;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036;regulation of Ras protein signal transduction#GO:0046578;positive regulation of multicellular organismal process#GO:0051240 leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;cell leading edge#GO:0031252;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ruffle membrane#GO:0032587;intracellular#GO:0005622;ruffle#GO:0001726;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=35414|UniProtKB=A6NKP2 A6NKP2 SDR42E2 PTHR10366:SF241 NAD DEPENDENT EPIMERASE/DEHYDRATASE SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 42E MEMBER 2-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091 HUMAN|HGNC=33888|UniProtKB=P0C6C1 P0C6C1 ANKRD34C PTHR24157:SF0 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 34C HUMAN|HGNC=30748|UniProtKB=Q9UKU6 Q9UKU6 TRHDE PTHR11533:SF40 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME cation binding#GO:0043169;metallopeptidase activity#GO:0008237;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;peptide binding#GO:0042277;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;peptidase activity#GO:0008233;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=44410|UniProtKB=H3BQL2 H3BQL2 GOLGA8T PTHR10881:SF62 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8H-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=26973|UniProtKB=Q711Q0 Q711Q0 CEFIP PTHR33775:SF2 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN HUMAN|HGNC=18401|UniProtKB=Q9H4P4 Q9H4P4 RNF41 PTHR15315:SF74 RING FINGER PROTEIN 41, 151 E3 UBIQUITIN-PROTEIN LIGASE NRDP1 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=2551|UniProtKB=Q13616 Q13616 CUL1 PTHR11932:SF126 CULLIN CULLIN-1 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Cul-1#P01239 HUMAN|HGNC=32487|UniProtKB=Q6NS38 Q6NS38 ALKBH2 PTHR31573:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2 DNA OXIDATIVE DEMETHYLASE ALKBH2 cation binding#GO:0043169;demethylase activity#GO:0032451;ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;dioxygenase activity#GO:0051213;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on DNA#GO:0140097;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;oxidative demethylation#GO:0070989;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;demethylation#GO:0070988;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 oxygenase#PC00177 HUMAN|HGNC=28115|UniProtKB=Q5QJ74 Q5QJ74 TBCEL PTHR15140:SF11 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE COFACTOR E-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein folding#GO:0006457;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=10547|UniProtKB=O75845 O75845 SC5D PTHR11863:SF139 STEROL DESATURASE LATHOSTEROL OXIDASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;steroid metabolic process#GO:0008202;lipid metabolic process#GO:0006629;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 oxidase#PC00175 HUMAN|HGNC=26011|UniProtKB=Q9NX95 Q9NX95 SYBU PTHR16208:SF4 MICROTUBULE-ASSOCIATED PROTEIN/SYNTAPHILIN SYNTABULIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;developmental process#GO:0032502;multicellular organism development#GO:0007275;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;axo-dendritic transport#GO:0008088;system development#GO:0048731;synapse organization#GO:0050808;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656 supramolecular complex#GO:0099080;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 SNARE protein#PC00034 HUMAN|HGNC=286|UniProtKB=P07550 P07550 ADRB2 PTHR24248:SF21 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR BETA-2 ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;organic cyclic compound binding#GO:0097159;transmembrane signaling receptor activity#GO:0004888 blood circulation#GO:0008015;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;second-messenger-mediated signaling#GO:0019932;regulation of muscle contraction#GO:0006937;regulation of cyclase activity#GO:0031279;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of blood vessel diameter#GO:0097746;regulation of system process#GO:0044057;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;negative regulation of multicellular organismal process#GO:0051241;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of blood pressure#GO:0045776;activation of adenylate cyclase activity#GO:0007190;regulation of anatomical structure size#GO:0090066;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;smooth muscle contraction#GO:0006939;cell communication#GO:0007154;regulation of systemic arterial blood pressure#GO:0003073;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of blood pressure#GO:0008217;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;cAMP-mediated signaling#GO:0019933;muscle system process#GO:0003012;muscle contraction#GO:0006936;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Beta2 adrenergic receptor signaling pathway#P04378>Beta2#P04440;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=29242|UniProtKB=A1X283 A1X283 SH3PXD2B PTHR15706:SF19 SH3 MULTIPLE DOMAIN SH3 AND PX DOMAIN-CONTAINING PROTEIN 2B phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 HUMAN|HGNC=1604|UniProtKB=P51677 P51677 CCR3 PTHR10489:SF649 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 3 response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response#GO:0006952;immune response#GO:0006955;inflammatory response#GO:0006954 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=28144|UniProtKB=Q5T6V5 Q5T6V5 C9orf64 PTHR21314:SF0 UNCHARACTERIZED QUEUOSINE SALVAGE PROTEIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=24139|UniProtKB=Q7Z7M8 Q7Z7M8 B3GNT8 PTHR11214:SF87 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 8 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;cellular polysaccharide biosynthetic process#GO:0033692;cellular polysaccharide metabolic process#GO:0044264;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=27750|UniProtKB=A6NDU8 A6NDU8 C5orf51 PTHR28494:SF1 UPF0600 PROTEIN C5ORF51 UPF0600 PROTEIN C5ORF51 HUMAN|HGNC=23726|UniProtKB=Q9H098 Q9H098 FAM107B PTHR16768:SF1 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A PROTEIN FAM107B HUMAN|HGNC=11183|UniProtKB=P18583 P18583 SON PTHR46528:SF1 PROTEIN SON PROTEIN SON RNA splicing factor#PC00148 HUMAN|HGNC=8113|UniProtKB=Q14990 Q14990 ODF1 PTHR17125:SF2 OUTER DENSE FIBER PROTEIN 1 OUTER DENSE FIBER PROTEIN 1 HUMAN|HGNC=26562|UniProtKB=Q5T1A1 Q5T1A1 DCST2 PTHR21041:SF6 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DC-STAMP DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=10606|UniProtKB=P22307 P22307 SCP2 PTHR24314:SF20 NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED NON-SPECIFIC LIPID-TRANSFER PROTEIN-RELATED transfer/carrier protein#PC00219 HUMAN|HGNC=30046|UniProtKB=Q96BK5 Q96BK5 PINX1 PTHR23149:SF27 G PATCH DOMAIN CONTAINING PROTEIN PIN2/TERF1-INTERACTING TELOMERASE INHIBITOR 1 RNA metabolism protein#PC00031 HUMAN|HGNC=17008|UniProtKB=Q92547 Q92547 TOPBP1 PTHR13561:SF20 DNA REPLICATION REGULATOR DPB11-RELATED DNA TOPOISOMERASE 2-BINDING PROTEIN 1 DNA metabolism protein#PC00009 HUMAN|HGNC=14628|UniProtKB=Q9BWT1 Q9BWT1 CDCA7 PTHR31169:SF2 OS05G0300700 PROTEIN CELL DIVISION CYCLE-ASSOCIATED PROTEIN 7 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=4104|UniProtKB=O76087 O76087 GAGE7 PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=12873|UniProtKB=O95409 O95409 ZIC2 PTHR19818:SF27 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=14360|UniProtKB=P78415 P78415 IRX3 PTHR11211:SF14 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=16719|UniProtKB=Q14147 Q14147 DHX34 PTHR18934:SF148 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX34-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 RNA helicase#PC00032 HUMAN|HGNC=29312|UniProtKB=Q9HCL3 Q9HCL3 ZFP14 PTHR24377:SF940 IP01015P-RELATED ZINC FINGER PROTEIN 14 HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11215|UniProtKB=O75602 O75602 SPAG6 PTHR23314:SF0 SPERM-ASSOCIATED ANTIGEN 6 ARMADILLO REPEAT-CONTAINING SPERM-ASSOCIATED ANTIGEN 6 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=30664|UniProtKB=Q9H078 Q9H078 CLPB PTHR11638:SF93 ATP-DEPENDENT CLP PROTEASE CASEINOLYTIC PEPTIDASE B PROTEIN HOMOLOG pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 HUMAN|HGNC=8051|UniProtKB=Q9NZJ9 Q9NZJ9 NUDT4 PTHR12629:SF6 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 2-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleotide diphosphatase activity#GO:0004551;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organophosphate catabolic process#GO:0046434;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphatase#PC00181 HUMAN|HGNC=12380|UniProtKB=Q99598 Q99598 TSNAX PTHR10741:SF5 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN-ASSOCIATED PROTEIN X catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;endoribonuclease activity#GO:0004521;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;ribonuclease activity#GO:0004540 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=17173|UniProtKB=Q9BWV1 Q9BWV1 BOC PTHR44170:SF3 PROTEIN SIDEKICK BROTHER OF CDO HUMAN|HGNC=3284|UniProtKB=Q14240 Q14240 EIF4A2 PTHR24031:SF720 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A-II nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=10064|UniProtKB=O75382 O75382 TRIM3 PTHR24104:SF21 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 3 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 ubiquitin-protein ligase#PC00234 Alzheimer disease-presenilin pathway#P00004>HAC1#P00131 HUMAN|HGNC=44669|UniProtKB=B4E2M5 B4E2M5 ANKRD66 PTHR24180:SF15 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 66 kinase inhibitor#PC00139 HUMAN|HGNC=28039|UniProtKB=Q9NPI7 Q9NPI7 KRCC1 PTHR46742:SF3 LYSINE-RICH COILED-COIL PROTEIN 1 LYSINE-RICH COILED-COIL PROTEIN 1 HUMAN|HGNC=27538|UniProtKB=P0C7N1 P0C7N1 OR8U8 PTHR48018:SF91 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8U1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=1093|UniProtKB=P07738 P07738 BPGM PTHR11931:SF11 PHOSPHOGLYCERATE MUTASE BISPHOSPHOGLYCERATE MUTASE mutase#PC00160 Glycolysis#P00024>Phosphoglyceromutase#P00680 HUMAN|HGNC=13241|UniProtKB=Q9H4K1 Q9H4K1 RIBC2 PTHR14517:SF10 RIB43A-RELATED RIB43A-LIKE WITH COILED-COILS PROTEIN 2 cytoskeletal protein#PC00085 HUMAN|HGNC=4915|UniProtKB=Q9H422 Q9H422 HIPK3 PTHR24058:SF45 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 3 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;PML body#GO:0016605 HUMAN|HGNC=5103|UniProtKB=O43364 O43364 HOXA2 PTHR45664:SF3 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-A2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=994|UniProtKB=O43521 O43521 BCL2L11 PTHR12044:SF9 BCL2 INTERACTING MEDIATOR OF CELL DEATH BCL-2-LIKE PROTEIN 11 meiosis I cell cycle phase#GO:0098764;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;cellular component organization#GO:0016043;cellular process#GO:0009987;M phase#GO:0000279;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;meiotic cell cycle process#GO:1903046;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;cell cycle phase#GO:0022403;meiosis I#GO:0007127 Apoptosis signaling pathway#P00006>Bim#P00325 HUMAN|HGNC=25756|UniProtKB=Q969M1 Q969M1 TOMM40L PTHR10802:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40B protein transmembrane transporter activity#GO:0008320;amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 primary active transporter#PC00068 HUMAN|HGNC=5019|UniProtKB=A6NHT5 A6NHT5 HMX3 PTHR46110:SF2 HOMEOBOX PROTEIN HMX HOMEOBOX PROTEIN HMX3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=12739|UniProtKB=O75554 O75554 WBP4 PTHR13173:SF10 WW DOMAIN BINDING PROTEIN 4 WW DOMAIN-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=15561|UniProtKB=Q9UBH0 Q9UBH0 IL36RN PTHR10078:SF32 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-36 RECEPTOR ANTAGONIST PROTEIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to lipopolysaccharide#GO:0071222;gene expression#GO:0010467;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of metabolic process#GO:0009893;response to biotic stimulus#GO:0009607;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 interleukin superfamily#PC00128 HUMAN|HGNC=37155|UniProtKB=P0CJ68 P0CJ68 MTRNR2L1 PTHR33895:SF18 HUMANIN-LIKE 4 HUMANIN-LIKE 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=15524|UniProtKB=Q86VZ1 Q86VZ1 P2RY8 PTHR24232:SF25 G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=23518|UniProtKB=Q96BP2 Q96BP2 CHCHD1 PTHR31278:SF2 CHCHD1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 HUMAN|HGNC=2052|UniProtKB=O75596 O75596 CLEC3A PTHR22799:SF2 TETRANECTIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 3 MEMBER A multicellular organismal process#GO:0032501;ossification#GO:0001503 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=13156|UniProtKB=P51508 P51508 ZNF81 PTHR24377:SF5 IP01015P-RELATED ZINC FINGER PROTEIN 81 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=3039|UniProtKB=O60469 O60469 DSCAM PTHR10075:SF51 BASIGIN RELATED DOWN SYNDROME CELL ADHESION MOLECULE cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=580|UniProtKB=O96018 O96018 APBA3 PTHR12345:SF9 SYNTENIN RELATED AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 3 amyloid-beta binding#GO:0001540;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;dendritic tree#GO:0097447;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Alzheimer disease-amyloid secretase pathway#P00003>X11alpha#P00084;Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093 HUMAN|HGNC=10645|UniProtKB=P47992 P47992 XCL1 PTHR12015:SF101 SMALL INDUCIBLE CYTOKINE A CYTOKINE SCM-1 BETA-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=4403|UniProtKB=P61952 P61952 GNG11 PTHR13809:SF1 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-11 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 HUMAN|HGNC=25716|UniProtKB=Q96BR5 Q96BR5 COA7 PTHR13891:SF1 UNCHARACTERIZED CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 HUMAN|HGNC=17070|UniProtKB=Q9UH65 Q9UH65 SWAP70 PTHR14383:SF6 SWAP-70 RECOMBINASE SWITCH-ASSOCIATED PROTEIN 70 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=371|UniProtKB=Q12802 Q12802 AKAP13 PTHR13944:SF18 AGAP007712-PA A-KINASE ANCHOR PROTEIN 13 Rho guanyl-nucleotide exchange factor activity#GO:0005089;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;Ras GTPase binding#GO:0017016;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;kinase binding#GO:0019900;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;Ras protein signal transduction#GO:0007265;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of Rho protein signal transduction#GO:0035023;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;regulation of small GTPase mediated signal transduction#GO:0051056;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;regulation of Ras protein signal transduction#GO:0046578;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;Rho protein signal transduction#GO:0007266;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 HUMAN|HGNC=269|UniProtKB=P54922 P54922 ADPRH PTHR22957:SF611 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN [PROTEIN ADP-RIBOSYLARGININE] HYDROLASE GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=44407|UniProtKB=I6L899 I6L899 GOLGA8R PTHR10881:SF62 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8H-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=23026|UniProtKB=Q9UJJ9 Q9UJJ9 GNPTG PTHR12630:SF6 N-LINKED OLIGOSACCHARIDE PROCESSING N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNIT GAMMA carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095 HUMAN|HGNC=8007|UniProtKB=Q99748 Q99748 NRTN PTHR12173:SF3 GDNF SUBFAMILY OF TGF-BETA FAMILY NEURTURIN binding#GO:0005488;receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 neurotrophic factor#PC00163 HUMAN|HGNC=1441|UniProtKB=Q05682 Q05682 CALD1 PTHR18949:SF0 CALDESMON CALDESMON non-motor actin binding protein#PC00165 HUMAN|HGNC=6891|UniProtKB=Q15555 Q15555 MAPRE2 PTHR10623:SF7 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;microtubule polymerization or depolymerization#GO:0031109;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule cytoskeleton organization#GO:0070507;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;protein localization to organelle#GO:0033365;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;protein localization#GO:0008104;organelle assembly#GO:0070925;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=8269|UniProtKB=Q8NG83 Q8NG83 OR2M3 PTHR26453:SF204 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2M3 transmembrane signal receptor#PC00197 HUMAN|HGNC=27222|UniProtKB=Q6ZMS7 Q6ZMS7 ZNF783 PTHR24390:SF97 ZINC FINGER PROTEIN PROTEIN ZNF783-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15999|UniProtKB=Q9NZV5 Q9NZV5 SELENON PTHR16213:SF78 UNCHARACTERIZED SELENOPROTEIN N inorganic ion homeostasis#GO:0098771;muscle organ development#GO:0007517;muscle cell differentiation#GO:0042692;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;animal organ development#GO:0048513;developmental process#GO:0032502;muscle structure development#GO:0061061;system development#GO:0048731;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;striated muscle tissue development#GO:0014706;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;striated muscle cell development#GO:0055002;skeletal muscle fiber development#GO:0048741;skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;tissue development#GO:0009888;muscle tissue development#GO:0060537;cell development#GO:0048468;muscle cell development#GO:0055001;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065;skeletal muscle tissue development#GO:0007519 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=11111|UniProtKB=Q14683 Q14683 SMC1A PTHR18937:SF170 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1A HUMAN|HGNC=1630|UniProtKB=P48509 P48509 CD151 PTHR19282:SF487 TETRASPANIN CD151 ANTIGEN intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=5275|UniProtKB=Q92993 Q92993 KAT5 PTHR10615:SF161 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT5 molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137;Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093 HUMAN|HGNC=16344|UniProtKB=A0A0G2JNF4 A0A0G2JNF4 KIR2DP1 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=30010|UniProtKB=Q8N2H9 Q8N2H9 PELI3 PTHR12098:SF9 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 3 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;protein K63-linked ubiquitination#GO:0070534;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=16747|UniProtKB=Q86UQ0 Q86UQ0 ZNF589 PTHR24381:SF343 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 589 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6224|UniProtKB=P22460 P22460 KCNA5 PTHR11537:SF250 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 5 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=4319|UniProtKB=P10071 P10071 GLI3 PTHR45718:SF5 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTIONAL ACTIVATOR GLI3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690;Hedgehog signaling pathway#P00025>Cubitus interruptus repressor#P00687 HUMAN|HGNC=14735|UniProtKB=Q8NGD0 Q8NGD0 OR4M1 PTHR48002:SF103 OLFACTORY RECEPTOR G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=28276|UniProtKB=Q6UX53 Q6UX53 METTL7B PTHR42912:SF14 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 7B methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155 HUMAN|HGNC=51517|UniProtKB=A0A494C086 A0A494C086 SPDYE21 PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=12945|UniProtKB=P17019 P17019 ZNF708 PTHR24384:SF201 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 273-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=7188|UniProtKB=Q99583 Q99583 MNT PTHR11969:SF54 MAX DIMERIZATION, MAD MAX-BINDING PROTEIN MNT cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=15022|UniProtKB=Q8NHC5 Q8NHC5 OR14A16 PTHR26452:SF806 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A16-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=18606|UniProtKB=Q9BYC2 Q9BYC2 OXCT2 PTHR13707:SF28 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID COENZYME A TRANSFERASE 2, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transferase#PC00220 HUMAN|HGNC=1865|UniProtKB=Q6UWW8 Q6UWW8 CES3 PTHR11559:SF259 CARBOXYLESTERASE CARBOXYLESTERASE 3 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;lipid catabolic process#GO:0016042;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 esterase#PC00097 HUMAN|HGNC=17563|UniProtKB=Q86U44 Q86U44 METTL3 PTHR12829:SF2 N6-ADENOSINE-METHYLTRANSFERASE N6-ADENOSINE-METHYLTRANSFERASE CATALYTIC SUBUNIT methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nuclear speck#GO:0016607;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA methyltransferase#PC00033 HUMAN|HGNC=24222|UniProtKB=Q86Y33 Q86Y33 CDC20B PTHR19918:SF4 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG B transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;regulation of cellular protein catabolic process#GO:1903362;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=19184|UniProtKB=Q8N1F8 Q8N1F8 STK11IP PTHR15454:SF63 NISCHARIN RELATED SERINE/THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 localization#GO:0051179;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15232|UniProtKB=Q8NH57 Q8NH57 OR52P1P PTHR26450:SF83 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52P1-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=9841|UniProtKB=Q15311 Q15311 RALBP1 PTHR12783:SF5 RALA BINDING PROTEIN 1 RALBP1 RALA-BINDING PROTEIN 1 GTPase-activating protein#PC00257 HUMAN|HGNC=6346|UniProtKB=Q9Y4X4 Q9Y4X4 KLF12 PTHR23235:SF56 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 12 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21167|UniProtKB=Q76G19 Q76G19 PDZD4 PTHR15545:SF4 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 PDZ DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=10845|UniProtKB=Q6ZVN7 Q6ZVN7 SEM1 PTHR16771:SF14 26 PROTEASOME COMPLEX SUBUNIT DSS1 PROTEIN SEM1, ISOFORM 2-RELATED DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 protease#PC00190 HUMAN|HGNC=9909|UniProtKB=Q15434 Q15434 RBMS2 PTHR24012:SF786 RNA BINDING PROTEIN RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 2 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28041|UniProtKB=Q86W34 Q86W34 AMZ2 PTHR32205:SF5 ARCHAEMETZINCIN-2-RELATED ARCHAEMETZINCIN-2 HUMAN|HGNC=6918|UniProtKB=O95983 O95983 MBD3 PTHR12396:SF12 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 3 HUMAN|HGNC=2019|UniProtKB=P35523 P35523 CLCN1 PTHR45720:SF4 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;chloride transport#GO:0006821;establishment of localization#GO:0051234;anion transport#GO:0006820;inorganic anion transport#GO:0015698;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=13312|UniProtKB=P78417 P78417 GSTO1 PTHR43968:SF5 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA-1 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidation-reduction process#GO:0055114;metabolic process#GO:0008152 HUMAN|HGNC=14010|UniProtKB=Q8IWI9 Q8IWI9 MGA PTHR11267:SF32 T-BOX PROTEIN-RELATED MAX GENE-ASSOCIATED PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 specification of symmetry#GO:0009799;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;heart looping#GO:0001947;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;heart development#GO:0007507;embryonic heart tube development#GO:0035050;determination of heart left/right asymmetry#GO:0061371;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;determination of bilateral symmetry#GO:0009855;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;determination of left/right symmetry#GO:0007368;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=604|UniProtKB=P41238 P41238 APOBEC1 PTHR13857:SF26 MRNA EDITING ENZYME C-U-EDITING ENZYME APOBEC-1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;demethylation#GO:0070988;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=30413|UniProtKB=Q86W33 Q86W33 TPRA1 PTHR15876:SF8 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 HUMAN|HGNC=986|UniProtKB=P12694 P12694 BCKDHA PTHR43380:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 dehydrogenase#PC00092 HUMAN|HGNC=11619|UniProtKB=Q15370 Q15370 ELOB PTHR13248:SF5 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2 ELONGIN-B membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=30184|UniProtKB=A2A3K4 A2A3K4 PTPDC1 PTHR23339:SF109 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE DOMAIN-CONTAINING PROTEIN 1 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein phosphatase#PC00195 HUMAN|HGNC=19014|UniProtKB=Q8IWZ5 Q8IWZ5 TRIM42 PTHR25465:SF13 FAMILY NOT NAMED TRIPARTITE MOTIF-CONTAINING PROTEIN 42 regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;cellular metabolic process#GO:0044237;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;positive regulation of metabolic process#GO:0009893;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;catabolic process#GO:0009056;positive regulation of autophagy#GO:0010508;positive regulation of biological process#GO:0048518;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;cellular catabolic process#GO:0044248;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 HUMAN|HGNC=1835|UniProtKB=P49716 P49716 CEBPD PTHR23334:SF3 CCAAT/ENHANCER BINDING PROTEIN CCAAT/ENHANCER-BINDING PROTEIN DELTA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=8572|UniProtKB=Q9UKS6 Q9UKS6 PACSIN3 PTHR23065:SF18 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 regulation of endocytosis#GO:0030100;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;endocytosis#GO:0006897;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;vesicle organization#GO:0016050 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=21998|UniProtKB=A2VEC9 A2VEC9 SSPOP PTHR11339:SF386 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED SCO-SPONDIN extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=9336|UniProtKB=P78395 P78395 PRAME PTHR14224:SF19 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 MELANOMA ANTIGEN PREFERENTIALLY EXPRESSED IN TUMORS cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|Ensembl=ENSG00000284169|UniProtKB=A0A1W2PRS3 A0A1W2PRS3 ENSG00000284169 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=11537|UniProtKB=O00268 O00268 TAF4 PTHR15138:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;RNA polymerase II general transcription initiation factor activity#GO:0016251 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 Huntington disease#P00029>TAFII130#P00806;General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=33601|UniProtKB=A6NGB0 A6NGB0 TMEM191C PTHR38498:SF1 TRANSMEMBRANE PROTEIN 191B-RELATED TRANSMEMBRANE PROTEIN 191B-RELATED HUMAN|HGNC=12133|UniProtKB=A0A0B4J273 A0A0B4J273 TRAV34 PTHR19433:SF84 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 34 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=9171|UniProtKB=O00592 O00592 PODXL PTHR12067:SF5 PODOCALYXIN PODOCALYXIN cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cell projection organization#GO:0030030;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;cell adhesion mediated by integrin#GO:0033627;biological adhesion#GO:0022610;regulation of cellular component organization#GO:0051128;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;localization of cell#GO:0051674;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell motility#GO:0048870;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;cell projection assembly#GO:0030031;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;positive regulation of cell adhesion#GO:0045785;cell migration#GO:0016477;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;positive regulation of cell-cell adhesion#GO:0022409 microvillus#GO:0005902;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;actin-based cell projection#GO:0098858;cell projection membrane#GO:0031253;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=3511|UniProtKB=Q9UQ84 Q9UQ84 EXO1 PTHR11081:SF8 FLAP ENDONUCLEASE FAMILY MEMBER EXONUCLEASE 1 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;endodeoxyribonuclease activity#GO:0004520;deoxyribonuclease activity#GO:0004536 exodeoxyribonuclease#PC00098 HUMAN|HGNC=26530|UniProtKB=Q96M91 Q96M91 CFAP53 PTHR31183:SF1 TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 53 HUMAN|HGNC=26551|UniProtKB=Q8IYY4 Q8IYY4 DZIP1L PTHR21502:SF8 ZINC FINGER PROTEIN DZIP1 ZINC FINGER PROTEIN DZIP1L vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=5921|UniProtKB=A0A075B6H9 A0A075B6H9 IGLV4-69 PTHR23267:SF164 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-69 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|Ensembl=ENSG00000275428|UniProtKB=A0A0G2JMS6 A0A0G2JMS6 ENSG00000275428 PTHR11412:SF150 MACROGLOBULIN / COMPLEMENT OVOSTATIN HOMOLOG 1-RELATED protease inhibitor#PC00191 HUMAN|HGNC=3551|UniProtKB=P00740 P00740 F9 PTHR24278:SF31 COAGULATION FACTOR COAGULATION FACTOR IX extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>FXIa#P00434;Blood coagulation#P00011>FIX#P00444;Blood coagulation#P00011>FIXa#P00422;Blood coagulation#P00011>FXI#P00460 HUMAN|HGNC=6021|UniProtKB=P40189 P40189 IL6ST PTHR23036:SF83 CYTOKINE RECEPTOR INTERLEUKIN-6 RECEPTOR SUBUNIT BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Signaling subunit#P00969 HUMAN|HGNC=19081|UniProtKB=Q9C0C2 Q9C0C2 TNKS1BP1 PTHR22042:SF2 TANKYRASE 1 BINDING PROTEIN 182 KDA TANKYRASE-1-BINDING PROTEIN HUMAN|HGNC=12999|UniProtKB=O43345 O43345 ZNF208 PTHR24376:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 208-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4168|UniProtKB=Q14393 Q14393 GAS6 PTHR24035:SF104 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN GROWTH ARREST-SPECIFIC PROTEIN 6 extracellular matrix protein#PC00102 HUMAN|HGNC=22948|UniProtKB=Q9NX02 Q9NX02 NLRP2 PTHR45690:SF18 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 2-RELATED HUMAN|HGNC=5586|UniProtKB=A0A0B4J1V1 A0A0B4J1V1 IGHV3-21 PTHR23266:SF357 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-11-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=16992|UniProtKB=Q7L1W4 Q7L1W4 LRRC8D PTHR45752:SF11 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8D hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 scaffold/adaptor protein#PC00226 HUMAN|HGNC=27351|UniProtKB=Q8WVE0 Q8WVE0 EEF1AKMT1 PTHR13200:SF0 UNCHARACTERIZED EEF1A LYSINE METHYLTRANSFERASE 1 HUMAN|HGNC=25364|UniProtKB=Q9H0R4 Q9H0R4 HDHD2 PTHR19288:SF46 4-NITROPHENYLPHOSPHATASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2 phosphatase#PC00181 HUMAN|HGNC=24855|UniProtKB=Q7Z6B0 Q7Z6B0 CCDC91 PTHR35072:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 91 COILED-COIL DOMAIN-CONTAINING PROTEIN 91 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;lysosomal transport#GO:0007041 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=18284|UniProtKB=Q12829 Q12829 RAB40B PTHR47980:SF16 LD44762P RAS-RELATED PROTEIN RAB-40B vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;protein secretion#GO:0009306;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=28702|UniProtKB=Q8N4Z0 Q8N4Z0 RAB42 PTHR24070:SF408 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAB-42 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=9115|UniProtKB=O15305 O15305 PMM2 PTHR10466:SF2 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE 2 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;monosaccharide metabolic process#GO:0005996;cellular localization#GO:0051641;carbohydrate derivative metabolic process#GO:1901135;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;protein localization to endoplasmic reticulum#GO:0070972;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein targeting to ER#GO:0045047;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;peptide transport#GO:0015833;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;carbohydrate derivative biosynthetic process#GO:1901137;cellular macromolecule localization#GO:0070727;protein N-linked glycosylation#GO:0006487;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;hexose metabolic process#GO:0019318;small molecule metabolic process#GO:0044281;glycosylation#GO:0070085 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 mutase#PC00160 Mannose metabolism#P02752>P-Mannose mutase#P03019 HUMAN|HGNC=10430|UniProtKB=Q15418 Q15418 RPS6KA1 PTHR24351:SF43 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 Ras Pathway#P04393>p90RSK#P04541;Interleukin signaling pathway#P00036>p90RSK#P00964;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;CCKR signaling map#P06959>RSK1/2#P07153;PDGF signaling pathway#P00047>p90RSK#P01142 HUMAN|HGNC=16104|UniProtKB=Q8IXH6 Q8IXH6 TP53INP2 PTHR31671:SF2 DIABETES AND OBESITY REGULATED, ISOFORM G TUMOR PROTEIN P53-INDUCIBLE NUCLEAR PROTEIN 2 positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;organelle assembly#GO:0070925;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229 HUMAN|HGNC=28197|UniProtKB=Q9BR84 Q9BR84 ZNF559 PTHR24381:SF77 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 559 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=24975|UniProtKB=Q15270 Q15270 NKX1-1 PTHR24340:SF26 HOMEOBOX PROTEIN NKX NK1 TRANSCRIPTION FACTOR-RELATED PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=25651|UniProtKB=Q9C0J8 Q9C0J8 WDR33 PTHR22836:SF0 WD40 REPEAT PROTEIN PRE-MRNA 3' END PROCESSING PROTEIN WDR33 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 RNA processing factor#PC00147 HUMAN|HGNC=3213|UniProtKB=P26641 P26641 EEF1G PTHR43986:SF4 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14188|UniProtKB=O75366 O75366 AVIL PTHR11977:SF33 VILLIN ADVILLIN cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=4389|UniProtKB=P09471 P09471 GNAO1 PTHR10218:SF302 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(O) SUBUNIT ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Enkephalin release#P05913>G-Protein (i)#P05974;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Endogenous cannabinoid signaling#P05730>Galpha#P05751;Gonadotropin-releasing hormone receptor pathway#P06664>gnai/o#P06773;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Goalpha#P00729;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 HUMAN|HGNC=28840|UniProtKB=O95521 O95521 PRAMEF1 PTHR14224:SF81 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 1-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=1301|UniProtKB=P57076 P57076 CFAP298 PTHR13238:SF0 PROTEIN C21ORF59 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 298 HUMAN|HGNC=3606|UniProtKB=P09467 P09467 FBP1 PTHR11556:SF11 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular carbohydrate metabolic process#GO:0044262;oligosaccharide biosynthetic process#GO:0009312;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 carbohydrate phosphatase#PC00066 HUMAN|HGNC=10494|UniProtKB=P26447 P26447 S100A4 PTHR11639:SF51 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A4 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=3431|UniProtKB=P21860 P21860 ERBB3 PTHR24416:SF88 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;basolateral plasma membrane#GO:0016323;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466 HUMAN|HGNC=10066|UniProtKB=Q3KNV8 Q3KNV8 PCGF3 PTHR45893:SF3 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 3 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone ubiquitination#GO:0016574;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;histone H2A ubiquitination#GO:0033522;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 HUMAN|HGNC=28435|UniProtKB=Q5BN46 Q5BN46 C9orf116 PTHR20899:SF1 PIERCE HOMOLOG UPF0691 PROTEIN C9ORF116 HUMAN|HGNC=12761|UniProtKB=P30291 P30291 WEE1 PTHR11042:SF72 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;M phase#GO:0000279;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;meiosis I cell cycle phase#GO:0098764;regulation of nuclear division#GO:0051783;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;regulation of cellular process#GO:0050794;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;regulation of meiotic cell cycle#GO:0051445;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;biological phase#GO:0044848;cell cycle#GO:0007049 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=33773|UniProtKB=Q6UWF9 Q6UWF9 FAM180A PTHR34034:SF2 PROTEIN FAM180A-RELATED PROTEIN FAM180A HUMAN|HGNC=20746|UniProtKB=P58004 P58004 SESN2 PTHR12474:SF2 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-2 cation binding#GO:0043169;amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;positive regulation of cellular metabolic process#GO:0031325;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cell communication#GO:0007154;regulation of macroautophagy#GO:0016241;response to organonitrogen compound#GO:0010243;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;process utilizing autophagic mechanism#GO:0061919;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;positive regulation of metabolic process#GO:0009893;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;TORC1 signaling#GO:0038202;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;regulation of autophagy#GO:0010506;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198 TORC2 complex#GO:0031932;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 peroxidase#PC00180 HUMAN|HGNC=25582|UniProtKB=Q9NVC3 Q9NVC3 SLC38A7 PTHR22950:SF192 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 7-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;basic amino acid transmembrane transporter activity#GO:0015174;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;L-glutamate transmembrane transporter activity#GO:0005313;neutral amino acid transmembrane transporter activity#GO:0015175;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;branched-chain amino acid transmembrane transporter activity#GO:0015658;dicarboxylic acid transmembrane transporter activity#GO:0005310;amide transmembrane transporter activity#GO:0042887;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171 transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 amino acid transporter#PC00046 HUMAN|HGNC=12927|UniProtKB=P52746 P52746 ZNF142 PTHR24409:SF298 ZINC FINGER PROTEIN 142 ZINC FINGER PROTEIN 142 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3720|UniProtKB=Q02790 Q02790 FKBP4 PTHR10516:SF25 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4 chaperone#PC00072 HUMAN|HGNC=12947|UniProtKB=P17020 P17020 ZNF16 PTHR24377:SF879 IP01015P-RELATED ZINC FINGER PROTEIN 16 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4313|UniProtKB=P23378 P23378 GLDC PTHR11773:SF1 GLYCINE DEHYDROGENASE, DECARBOXYLATING GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL cation binding#GO:0043169;amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;heterocyclic compound binding#GO:1901363;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 dehydrogenase#PC00092 HUMAN|HGNC=17497|UniProtKB=Q8WZA0 Q8WZA0 LZIC PTHR16505:SF8 PROTEIN LZIC PROTEIN LZIC HUMAN|HGNC=23495|UniProtKB=Q5T2Q4 Q5T2Q4 CCNYL2 PTHR14248:SF25 CYCLIN Y, ISOFORM A CYCLIN-Y-LIKE PROTEIN 2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;positive regulation of cell cycle#GO:0045787;positive regulation of protein modification process#GO:0031401;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 HUMAN|HGNC=6166|UniProtKB=P19827 P19827 ITIH1 PTHR10338:SF106 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H1 protease inhibitor#PC00191 HUMAN|HGNC=1356|UniProtKB=O94905 O94905 ERLIN2 PTHR15351:SF4 ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG ERLIN-2 lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;cholesterol binding#GO:0015485;sterol binding#GO:0032934;steroid binding#GO:0005496 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=14600|UniProtKB=O76081 O76081 RGS20 PTHR10845:SF175 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 20 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=40050|UniProtKB=D6RGH6 D6RGH6 MCIDAS PTHR13372:SF3 GEMININ MULTICILIN cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of DNA replication#GO:0008156;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA biosynthetic process#GO:0071897;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;regulation of cell cycle#GO:0051726;DNA replication#GO:0006260;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of DNA replication#GO:0006275;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=30770|UniProtKB=Q8N6N6 Q8N6N6 NATD1 PTHR31435:SF9 PROTEIN NATD1 PROTEIN NATD1 HUMAN|HGNC=21897|UniProtKB=Q8N2E2 Q8N2E2 VWDE PTHR14949:SF42 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 VON WILLEBRAND FACTOR D AND EGF DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 HUMAN|HGNC=7587|UniProtKB=P60660 P60660 MYL6 PTHR23048:SF39 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT POLYPEPTIDE 6 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=23176|UniProtKB=Q6H9L7 Q6H9L7 ISM2 PTHR10239:SF28 ISTHMIN-2 ISTHMIN-2 HUMAN|HGNC=7038|UniProtKB=O00587 O00587 MFNG PTHR10811:SF6 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of Notch signaling pathway#GO:0008593;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signaling#GO:0023052;Notch signaling pathway#GO:0007219 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Fringe#P01107 HUMAN|HGNC=10734|UniProtKB=O95754 O95754 SEMA4F PTHR11036:SF72 SEMAPHORIN SEMAPHORIN-4F receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=26031|UniProtKB=Q9NUD9 Q9NUD9 PIGV PTHR12468:SF2 GPI MANNOSYLTRANSFERASE 2 GPI MANNOSYLTRANSFERASE 2 protein modifying enzyme#PC00260 HUMAN|HGNC=28158|UniProtKB=Q8NBP5 Q8NBP5 MFSD9 PTHR23504:SF14 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 9 HUMAN|HGNC=20473|UniProtKB=Q9BX63 Q9BX63 BRIP1 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN pyrophosphatase activity#GO:0016462;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;M phase#GO:0000279;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;meiosis I cell cycle phase#GO:0098764;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA helicase#PC00011 HUMAN|HGNC=33861|UniProtKB=Q7Z3B0 Q7Z3B0 SMIM15 PTHR28644:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 15 SMALL INTEGRAL MEMBRANE PROTEIN 15 HUMAN|HGNC=14973|UniProtKB=Q9Y5X1 Q9Y5X1 SNX9 PTHR45827:SF2 SORTING NEXIN SORTING NEXIN-9 scaffold/adaptor protein#PC00226 HUMAN|HGNC=13672|UniProtKB=Q9Y2Y9 Q9Y2Y9 KLF13 PTHR23235:SF21 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 13 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23685|UniProtKB=Q5VWJ9 Q5VWJ9 SNX30 PTHR45949:SF1 SORTING NEXIN-4 SORTING NEXIN-30 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20816|UniProtKB=Q96QT6 Q96QT6 PHF12 PTHR46309:SF1 PHD FINGER PROTEIN 12 PHD FINGER PROTEIN 12 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=28539|UniProtKB=Q8IYV9 Q8IYV9 IZUMO1 PTHR35540:SF1 IZUMO SPERM-EGG FUSION PROTEIN 1 IZUMO SPERM-EGG FUSION PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cell recognition#GO:0008037;plasma membrane fusion#GO:0045026;fertilization#GO:0009566;cellular process involved in reproduction in multicellular organism#GO:0022412;membrane organization#GO:0061024;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;multi-organism process#GO:0051704;cell-cell recognition#GO:0009988;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;membrane fusion#GO:0061025;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;multi-organism reproductive process#GO:0044703 bounding membrane of organelle#GO:0098588;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=18066|UniProtKB=P59095 P59095 STARD6 PTHR46374:SF2 PROTEIN CBG07384 STAR-RELATED LIPID TRANSFER PROTEIN 6 HUMAN|HGNC=17349|UniProtKB=O43172 O43172 PRPF4 PTHR19846:SF0 WD40 REPEAT PROTEIN U4/U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP4 RNA splicing factor#PC00148 mRNA splicing#P00058>U4#P01476;mRNA splicing#P00058>U6#P01473 HUMAN|HGNC=6234|UniProtKB=Q96PR1 Q96PR1 KCNC2 PTHR11537:SF172 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;cell leading edge#GO:0031252;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;cell body#GO:0044297;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=31409|UniProtKB=Q2I0M4 Q2I0M4 LRRC26 PTHR46473:SF2 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 26 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;molecular function regulator#GO:0098772;protein binding#GO:0005515;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 HUMAN|HGNC=6529|UniProtKB=Q13094 Q13094 LCP2 PTHR14098:SF1 SH2 DOMAIN CONTAINING PROTEIN LYMPHOCYTE CYTOSOLIC PROTEIN 2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 scaffold/adaptor protein#PC00226 T cell activation#P00053>SLP-76#P01321 HUMAN|HGNC=1048|UniProtKB=Q9H2M3 Q9H2M3 BHMT2 PTHR46120:SF3 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 S-METHYLMETHIONINE--HOMOCYSTEINE S-METHYLTRANSFERASE BHMT2 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155 HUMAN|HGNC=2155|UniProtKB=P51911 P51911 CNN1 PTHR18959:SF43 CALPONIN/TRANSGELIN CALPONIN-1 non-motor actin binding protein#PC00165 HUMAN|HGNC=21726|UniProtKB=Q96PE2 Q96PE2 ARHGEF17 PTHR12877:SF15 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 17 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=29038|UniProtKB=Q5T2D3 Q5T2D3 OTUD3 PTHR12419:SF7 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 3 hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081 HUMAN|HGNC=20243|UniProtKB=Q8TAV3 Q8TAV3 CYP2W1 PTHR24300:SF291 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2W1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=30927|UniProtKB=Q9NP91 Q9NP91 SLC6A20 PTHR11616:SF44 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT TRANSPORTER XTRP3 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 HUMAN|HGNC=11157|UniProtKB=P09234 P09234 SNRPC PTHR31148:SF1 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;U1 snRNP#GO:0005685;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229 HUMAN|HGNC=8967|UniProtKB=O95427 O95427 PIGN PTHR12250:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS N GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=24018|UniProtKB=Q9H568 Q9H568 ACTL8 PTHR11937:SF208 ACTIN ACTIN-LIKE PROTEIN 8 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 actin and actin related protein#PC00039 HUMAN|HGNC=464|UniProtKB=P03971 P03971 AMH PTHR15009:SF4 MUELLERIAN-INHIBITING FACTOR MUELLERIAN-INHIBITING FACTOR Gonadotropin-releasing hormone receptor pathway#P06664>MIS#P06750 HUMAN|Ensembl=ENSG00000188897|UniProtKB=M0QZD8 M0QZD8 LOC400499 PTHR23345:SF31 VITELLOGENIN-RELATED APOLIPOPHORINS transporter activity#GO:0005215;lipid transporter activity#GO:0005319 storage protein#PC00210 HUMAN|HGNC=13718|UniProtKB=P15407 P15407 FOSL1 PTHR23351:SF6 FOS TRANSCRIPTION FACTOR-RELATED FOS-RELATED ANTIGEN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 HUMAN|HGNC=25231|UniProtKB=Q9Y548 Q9Y548 YIPF1 PTHR12822:SF4 UNCHARACTERIZED PROTEIN YIPF1 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=1801|UniProtKB=O95674 O95674 CDS2 PTHR13773:SF4 PHOSPHATIDATE CYTIDYLYLTRANSFERASE PHOSPHATIDATE CYTIDYLYLTRANSFERASE 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=27879|UniProtKB=P0DP72 P0DP72 VSIG10L2 PTHR11640:SF150 NEPHRIN V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE 2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=15574|UniProtKB=Q8TDY2 Q8TDY2 RB1CC1 PTHR13222:SF1 RB1-INDUCIBLE COILED-COIL RB1-INDUCIBLE COILED-COIL PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;endoplasmic reticulum organization#GO:0007029;macroautophagy#GO:0016236;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;endomembrane system organization#GO:0010256;autophagy of mitochondrion#GO:0000422;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;nucleus organization#GO:0006997;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;lysosomal microautophagy#GO:0016237;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;organelle disassembly#GO:1903008;regulation of primary metabolic process#GO:0080090;organelle assembly#GO:0070925;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;autophagy of nucleus#GO:0044804;peroxisome organization#GO:0007031 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;membrane#GO:0016020;whole membrane#GO:0098805;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 scaffold/adaptor protein#PC00226 HUMAN|HGNC=21224|UniProtKB=Q96AP4 Q96AP4 ZUP1 PTHR24403:SF92 ZINC FINGER PROTEIN ZINC FINGER-CONTAINING UBIQUITIN PEPTIDASE 1 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=14090|UniProtKB=Q9NP90 Q9NP90 RAB9B PTHR47981:SF17 RAB FAMILY RAS-RELATED PROTEIN RAB-9B lysosome organization#GO:0007040;vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=10740|UniProtKB=Q9H3T2 Q9H3T2 SEMA6C PTHR11036:SF11 SEMAPHORIN SEMAPHORIN-6C receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=4657|UniProtKB=Q13889 Q13889 GTF2H3 PTHR12831:SF0 TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3 DNA repair#GO:0006281;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;nucleotide-excision repair#GO:0006289;phosphorylation of RNA polymerase II C-terminal domain#GO:0070816;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 HUMAN|HGNC=8209|UniProtKB=Q8NGS2 Q8NGS2 OR1J2 PTHR48001:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1J2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=29644|UniProtKB=Q9NZC3 Q9NZC3 GDE1 PTHR46320:SF1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 phosphodiesterase#PC00185 HUMAN|HGNC=15977|UniProtKB=Q9BYE0 Q9BYE0 HES7 PTHR10985:SF84 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|Ensembl=ENSG00000282168|UniProtKB=A0A499FJF3 A0A499FJF3 ENSG00000282168 PTHR15670:SF4 RHO GTPASE ACTIVATING PROTEIN 11A RHO GTPASE-ACTIVATING PROTEIN 11A-RELATED GTPase-activating protein#PC00257 HUMAN|HGNC=28547|UniProtKB=Q8N0U7 Q8N0U7 C1orf87 PTHR34830:SF1 SIMILAR TO HYPOTHETICAL PROTEIN MGC34837 SIMILAR TO HYPOTHETICAL PROTEIN MGC34837 HUMAN|HGNC=16967|UniProtKB=P56211 P56211 ARPP19 PTHR10358:SF4 ENDOSULFINE CAMP-REGULATED PHOSPHOPROTEIN 19 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;phosphatase inhibitor activity#GO:0019212;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096;protein phosphatase inhibitor activity#GO:0004864 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of protein dephosphorylation#GO:0035308;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of dephosphorylation#GO:0035305;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=12103|UniProtKB=A0A0B4J240 A0A0B4J240 TRAV10 PTHR19433:SF103 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 10 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=13771|UniProtKB=Q9BQB4 Q9BQB4 SOST PTHR14903:SF4 SCLEROSTIN-RELATED SCLEROSTIN protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;negative regulation of cellular response to growth factor stimulus#GO:0090288;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;Wnt signaling pathway#GO:0016055;response to organic substance#GO:0010033;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;ossification#GO:0001503;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=14015|UniProtKB=Q9BZC1 Q9BZC1 CELF4 PTHR24012:SF721 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 4 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5550|UniProtKB=P23083 P23083 IGHV1-2 PTHR23266:SF272 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=33446|UniProtKB=A6NHG4 A6NHG4 DDTL PTHR11954:SF39 D-DOPACHROME DECARBOXYLASE D-DOPACHROME DECARBOXYLASE-LIKE PROTEIN decarboxylase#PC00089 HUMAN|HGNC=25692|UniProtKB=Q9HA90 Q9HA90 EFCC1 PTHR11595:SF25 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER EF-HAND AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GTPase binding#GO:0051020;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation elongation factor#PC00222 HUMAN|Ensembl=ENSG00000250673|UniProtKB=A0A1B0GV85 A0A1B0GV85 REELD1 PTHR45828:SF13 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN 1 reductase#PC00198 HUMAN|HGNC=13972|UniProtKB=Q9UGF6 Q9UGF6 OR5V1 PTHR26453:SF295 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5V1 transmembrane signal receptor#PC00197 HUMAN|HGNC=15991|UniProtKB=Q96KR4 Q96KR4 LMLN PTHR10942:SF0 LEISHMANOLYSIN-LIKE PEPTIDASE LEISHMANOLYSIN-LIKE PEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=29211|UniProtKB=A4D1T9 A4D1T9 PRSS37 PTHR24271:SF61 KALLIKREIN-RELATED INACTIVE SERINE PROTEASE 37-RELATED regulation of biological process#GO:0050789;fertilization#GO:0009566;reproduction#GO:0000003;single fertilization#GO:0007338;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;regulation of multi-organism process#GO:0043900;regulation of reproductive process#GO:2000241;multi-organism reproductive process#GO:0044703;positive regulation of biological process#GO:0048518;multi-organism process#GO:0051704;acrosome reaction#GO:0007340 acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=26533|UniProtKB=Q96M83 Q96M83 CCDC7 PTHR22035:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 7 COILED-COIL DOMAIN-CONTAINING PROTEIN 7 HUMAN|HGNC=22225|UniProtKB=Q96JN2 Q96JN2 CCDC136 PTHR15715:SF26 CENTROSOMAL PROTEIN OF 170 KDA COILED-COIL DOMAIN-CONTAINING PROTEIN 136 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17778|UniProtKB=A6NER3 A6NER3 GAGE12J PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=15646|UniProtKB=Q8IXQ5 Q8IXQ5 KLHL7 PTHR24412:SF435 KELCH PROTEIN KELCH-LIKE PROTEIN 7 scaffold/adaptor protein#PC00226 HUMAN|HGNC=32249|UniProtKB=Q6UY27 Q6UY27 PATE2 PTHR47884:SF1 PROSTATE AND TESTIS EXPRESSED PROTEIN 2 PROSTATE AND TESTIS EXPRESSED PROTEIN 2 HUMAN|HGNC=11713|UniProtKB=Q9Y2W6 Q9Y2W6 TDRKH PTHR22948:SF18 TUDOR DOMAIN CONTAINING PROTEIN TUDOR AND KH DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=4553|UniProtKB=P07203 P07203 GPX1 PTHR11592:SF41 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 1 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;response to inorganic substance#GO:0010035;response to oxygen-containing compound#GO:1901700;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;response to oxidative stress#GO:0006979;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 peroxidase#PC00180 HUMAN|HGNC=27052|UniProtKB=Q6IPR1 Q6IPR1 ETFRF1 PTHR21024:SF0 GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1 HUMAN|HGNC=5297|UniProtKB=P46098 P46098 HTR3A PTHR18945:SF52 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422;Gonadotropin-releasing hormone receptor pathway#P06664>5-HT3AR#P06833 HUMAN|HGNC=20310|UniProtKB=Q5TC63 Q5TC63 GRTP1 PTHR22957:SF359 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN GROWTH HORMONE-REGULATED TBC PROTEIN 1 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=11168|UniProtKB=Q13884 Q13884 SNTB1 PTHR10554:SF11 SYNTROPHIN BETA-1-SYNTROPHIN membrane protein complex#GO:0098796;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=3360|UniProtKB=O43768 O43768 ENSA PTHR10358:SF21 ENDOSULFINE ALPHA-ENDOSULFINE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;phosphatase inhibitor activity#GO:0019212;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096;protein phosphatase inhibitor activity#GO:0004864 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of protein dephosphorylation#GO:0035308;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of dephosphorylation#GO:0035305;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2903|UniProtKB=P78352 P78352 DLG4 PTHR23119:SF33 DISCS LARGE DISKS LARGE HOMOLOG 4-RELATED establishment or maintenance of cell polarity#GO:0007163;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;developmental process#GO:0032502;biological adhesion#GO:0022610;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to organelle#GO:0033365;cell-cell signaling#GO:0007267;signaling#GO:0023052;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;neuromuscular junction#GO:0031594;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;basolateral plasma membrane#GO:0016323;ion channel complex#GO:0034702;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Huntington disease#P00029>PSD-95#P00789 HUMAN|HGNC=26088|UniProtKB=Q3BBV0 Q3BBV0 NBPF1 PTHR14199:SF40 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 1 HUMAN|HGNC=5992|UniProtKB=P01584 P01584 IL1B PTHR10078:SF30 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 BETA positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to lipopolysaccharide#GO:0071222;gene expression#GO:0010467;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of metabolic process#GO:0009893;response to biotic stimulus#GO:0009607;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 interleukin superfamily#PC00128 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 HUMAN|HGNC=15197|UniProtKB=Q8NH61 Q8NH61 OR51F2 PTHR26450:SF87 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51F2 transmembrane signal receptor#PC00197 HUMAN|HGNC=12692|UniProtKB=P08670 P08670 VIM PTHR45652:SF5 GLIAL FIBRILLARY ACIDIC PROTEIN VIMENTIN HUMAN|HGNC=272|UniProtKB=Q9UGN5 Q9UGN5 PARP2 PTHR10459:SF80 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 2 transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 HUMAN|HGNC=25950|UniProtKB=Q6V9R5 Q6V9R5 ZNF562 PTHR24384:SF222 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 562 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=26125|UniProtKB=Q8TB22 Q8TB22 SPATA20 PTHR42899:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 HUMAN|HGNC=28585|UniProtKB=Q9UGY1 Q9UGY1 NOL12 PTHR14577:SF0 NUCLEOLAR PROTEIN 12 NUCLEOLAR PROTEIN 12 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=8068|UniProtKB=P52948 P52948 NUP98 PTHR23198:SF6 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;chromosome organization#GO:0051276;organelle organization#GO:0006996;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=457|UniProtKB=P17707 P17707 AMD1 PTHR11570:SF0 S-ADENOSYLMETHIONINE DECARBOXYLASE S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME decarboxylase#PC00089 HUMAN|HGNC=7441|UniProtKB=P46199 P46199 MTIF2 PTHR43381:SF5 TRANSLATION INITIATION FACTOR IF-2-RELATED TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL translation initiation factor#PC00224 HUMAN|HGNC=19970|UniProtKB=O75586 O75586 MED6 PTHR13104:SF0 MED-6-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 6 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 transcription cofactor#PC00217 HUMAN|HGNC=23438|UniProtKB=Q8IVF1 Q8IVF1 NUTM2A PTHR22879:SF14 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 2A-RELATED HUMAN|HGNC=13447|UniProtKB=Q9H2H9 Q9H2H9 SLC38A1 PTHR22950:SF184 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 amino acid transporter#PC00046 HUMAN|HGNC=2547|UniProtKB=Q9UBR2 Q9UBR2 CTSZ PTHR12411:SF845 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN Z cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=16963|UniProtKB=Q7L523 Q7L523 RRAGA PTHR11259:SF7 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN A pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 signal transduction#GO:0007165;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to starvation#GO:0009267;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of autophagy#GO:0010506;cellular metabolic process#GO:0044237;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;nucleus#GO:0005634;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=7694|UniProtKB=O14561 O14561 NDUFAB1 PTHR20863:SF64 ACYL CARRIER PROTEIN ACYL CARRIER PROTEIN, MITOCHONDRIAL small molecule binding#GO:0036094;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 HUMAN|HGNC=8540|UniProtKB=Q96G91 Q96G91 P2RY11 PTHR24231:SF46 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 11 G-protein coupled receptor#PC00021 HUMAN|HGNC=18250|UniProtKB=Q8WUB8 Q8WUB8 PHF10 PTHR10615:SF174 HISTONE ACETYLTRANSFERASE PHD FINGER PROTEIN 10 molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=8100|UniProtKB=Q02509 Q02509 OC90 PTHR11716:SF1 PHOSPHOLIPASE A2 FAMILY MEMBER OTOCONIN-90 phospholipase#PC00186 HUMAN|HGNC=19178|UniProtKB=Q96FZ5 Q96FZ5 CMTM7 PTHR22776:SF89 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 7 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=26366|UniProtKB=Q17R55 Q17R55 FAM187B PTHR32178:SF8 FAM187 PROTEIN FAM187B immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=2932|UniProtKB=Q13316 Q13316 DMP1 PTHR23400:SF0 DENTIN MATRIX ACIDIC PHOSPHOPROTEIN 1 DENTIN MATRIX ACIDIC PHOSPHOPROTEIN 1 HUMAN|HGNC=4893|UniProtKB=P14210 P14210 HGF PTHR24261:SF8 PLASMINOGEN-RELATED HEPATOCYTE GROWTH FACTOR serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 HUMAN|HGNC=19859|UniProtKB=Q8N9U0 Q8N9U0 TC2N PTHR46887:SF1 TANDEM C2 DOMAINS NUCLEAR PROTEIN TANDEM C2 DOMAINS NUCLEAR PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=11445|UniProtKB=Q15833 Q15833 STXBP2 PTHR11679:SF27 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 2 syntaxin binding#GO:0019905;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488;syntaxin-1 binding#GO:0017075 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of neurotransmitter levels#GO:0001505;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;export from cell#GO:0140352 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=4490|UniProtKB=Q9UPC5 Q9UPC5 GPR34 PTHR24233:SF1 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 34-RELATED nucleotide binding#GO:0000166;signaling receptor activity#GO:0038023;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=19677|UniProtKB=Q8TBZ2 Q8TBZ2 MYCBPAP PTHR12276:SF54 EPSIN/ENT-RELATED MYCBP-ASSOCIATED PROTEIN HUMAN|HGNC=4669|UniProtKB=O00178 O00178 GTPBP1 PTHR43721:SF9 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation elongation factor#PC00222 HUMAN|HGNC=8989|UniProtKB=O15428 O15428 PIN1P1 PTHR10657:SF30 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PIN1-LIKE PROTEIN-RELATED isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=28270|UniProtKB=Q96D70 Q96D70 R3HDM4 PTHR32019:SF2 R3H DOMAIN-CONTAINING PROTEIN 4 R3H DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=14995|UniProtKB=Q8NGY0 Q8NGY0 OR10X1 PTHR24242:SF264 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 10X1 G-protein coupled receptor#PC00021 HUMAN|HGNC=6111|UniProtKB=Q13576 Q13576 IQGAP2 PTHR14149:SF12 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP2 GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;GTPase binding#GO:0051020;enzyme binding#GO:0019899;calmodulin binding#GO:0005516;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rho GTPase binding#GO:0017048;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;Rac GTPase binding#GO:0048365;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 HUMAN|HGNC=28127|UniProtKB=Q9BU20 Q9BU20 CPLANE2 PTHR14983:SF1 UNCHARACTERIZED CILIOGENESIS AND PLANAR POLARITY EFFECTOR 2 HUMAN|HGNC=9467|UniProtKB=O60256 O60256 PRPSAP2 PTHR10210:SF29 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172 HUMAN|HGNC=27016|UniProtKB=A1KXE4 A1KXE4 FAM168B PTHR31844:SF2 MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR-RELATED MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR myelin protein#PC00161 HUMAN|HGNC=2372|UniProtKB=Q9ULK4 Q9ULK4 MED23 PTHR12691:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=13210|UniProtKB=Q9H0F7 Q9H0F7 ARL6 PTHR11711:SF21 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 G-protein#PC00020 HUMAN|HGNC=20837|UniProtKB=Q6QHF9 Q6QHF9 PAOX PTHR10742:SF405 FLAVIN MONOAMINE OXIDASE PEROXISOMAL N(1)-ACETYL-SPERMINE/SPERMIDINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 HUMAN|HGNC=10908|UniProtKB=P49281 P49281 SLC11A2 PTHR11706:SF40 SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;iron ion transmembrane transporter activity#GO:0005381;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=32348|UniProtKB=A2A3L6 A2A3L6 TTC24 PTHR47050:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 24 TETRATRICOPEPTIDE REPEAT PROTEIN 24 HUMAN|HGNC=33832|UniProtKB=O75200 O75200 NPIPB7 PTHR15438:SF4 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER B15-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7002|UniProtKB=A6NDR6 A6NDR6 MEIS3P1 PTHR11850:SF332 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS3-LIKE 1-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;visual system development#GO:0150063;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=1435|UniProtKB=P22676 P22676 CALB2 PTHR19972:SF4 CALBINDIN CALRETININ cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of signaling#GO:0023051;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;synaptic signaling#GO:0099536;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;anatomical structure homeostasis#GO:0060249;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular cation homeostasis#GO:0030003;trans-synaptic signaling#GO:0099537;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular ion homeostasis#GO:0006873;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;cellular chemical homeostasis#GO:0055082;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;metal ion homeostasis#GO:0055065 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;terminal bouton#GO:0043195;dendrite#GO:0030425;cytosol#GO:0005829;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane#GO:0005886 calmodulin-related#PC00061 HUMAN|HGNC=30304|UniProtKB=Q6ZS82 Q6ZS82 RGS9BP PTHR21029:SF1 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G-PROTEIN SIGNALING 9-BINDING PROTEIN HUMAN|HGNC=31932|UniProtKB=Q5VVY1 Q5VVY1 METTL11B PTHR12753:SF2 AD-003 - RELATED ALPHA N-TERMINAL PROTEIN METHYLTRANSFERASE 1B methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein alkylation#GO:0008213;protein methylation#GO:0006479;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 methyltransferase#PC00155 HUMAN|HGNC=4758|UniProtKB=P23527 P23527 H2BC17 PTHR23428:SF325 HISTONE H2B HISTONE H2B TYPE 1-O nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=2519|UniProtKB=P17812 P17812 CTPS1 PTHR11550:SF8 CTP SYNTHASE CTP SYNTHASE 1 identical protein binding#GO:0042802;ligase activity#GO:0016874;protein binding#GO:0005515;binding#GO:0005488;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;pyrimidine nucleobase metabolic process#GO:0006206;pyrimidine nucleotide biosynthetic process#GO:0006221;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 De novo pyrimidine ribonucleotides biosythesis#P02740>CTP synthase#P02931 HUMAN|Ensembl=ENSG00000277535|UniProtKB=A0A0U1RQG5 A0A0U1RQG5 ENSG00000277535 PTHR32157:SF0 GENE 6268-RELATED GENE 6268-RELATED HUMAN|HGNC=3824|UniProtKB=Q05932 Q05932 FPGS PTHR11136:SF5 FOLYLPOLYGLUTAMATE SYNTHASE-RELATED FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;pteridine-containing compound metabolic process#GO:0042558;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;heterocycle biosynthetic process#GO:0018130;amide biosynthetic process#GO:0043604;folic acid-containing compound biosynthetic process#GO:0009396;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 HUMAN|HGNC=11835|UniProtKB=P51854 P51854 TKTL1 PTHR43195:SF2 TRANSKETOLASE TRANSKETOLASE-LIKE PROTEIN 1 cation binding#GO:0043169;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 transketolase#PC00221 HUMAN|HGNC=3048|UniProtKB=Q02413 Q02413 DSG1 PTHR24025:SF9 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cadherin#PC00057 HUMAN|HGNC=848|UniProtKB=P56134 P56134 ATP5MF PTHR13080:SF16 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular localization#GO:0051641;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;mitochondrial transmembrane transport#GO:1990542;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;intracellular transport#GO:0046907;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial transport#GO:0006839;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;establishment of localization in cell#GO:0051649;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 HUMAN|HGNC=1596|UniProtKB=O75909 O75909 CCNK PTHR10026:SF144 CYCLIN CYCLIN-K cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of DNA-templated transcription, elongation#GO:0032784;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 kinase activator#PC00138 Cell cycle#P00013>CdkC#P00489 HUMAN|HGNC=14891|UniProtKB=Q9NXW2 Q9NXW2 DNAJB12 PTHR43908:SF8 AT29763P-RELATED DNAJ HOMOLOG SUBFAMILY B MEMBER 12 heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488;Hsp70 protein binding#GO:0030544 cellular response to misfolded protein#GO:0071218;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;chaperone-mediated protein folding#GO:0061077;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;cellular protein catabolic process#GO:0044257;response to topologically incorrect protein#GO:0035966;'de novo' protein folding#GO:0006458;ubiquitin-dependent ERAD pathway#GO:0030433;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=11544|UniProtKB=Q15544 Q15544 TAF11 PTHR13218:SF16 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=9859|UniProtKB=P52306 P52306 RAP1GDS1 PTHR10957:SF2 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 positive regulation of catalytic activity#GO:0043085;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of GTPase activity#GO:0043547;positive regulation of molecular function#GO:0044093;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=12693|UniProtKB=P01282 P01282 VIP PTHR11213:SF5 GLUCAGON-FAMILY NEUROPEPTIDE VIP PEPTIDES neuropeptide hormone activity#GO:0005184;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 organic hydroxy compound transport#GO:0015850;regulation of adenylate cyclase activity#GO:0045761;regulation of protein metabolic process#GO:0051246;regulation of metal ion transport#GO:0010959;regulation of blood vessel diameter#GO:0097746;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;regulation of biological process#GO:0050789;secretion#GO:0046903;cognition#GO:0050890;epithelial cell proliferation#GO:0050673;reproductive process#GO:0022414;regulation of multi-organism process#GO:0043900;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of phospholipase C activity#GO:0010863;regulation of protein localization#GO:0032880;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;macromolecule catabolic process#GO:0009057;regulation of multicellular organismal process#GO:0051239;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;programmed cell death#GO:0012501;negative regulation of transport#GO:0051051;positive regulation of macromolecule metabolic process#GO:0010604;circulatory system process#GO:0003013;primary metabolic process#GO:0044238;negative regulation of cell death#GO:0060548;reproduction#GO:0000003;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;positive regulation of secretion by cell#GO:1903532;export from cell#GO:0140352;positive regulation of lipase activity#GO:0060193;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of signaling#GO:0023051;behavior#GO:0007610;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;organonitrogen compound catabolic process#GO:1901565;regulation of system process#GO:0044057;regulation of protein catabolic process#GO:0042176;cation transport#GO:0006812;regulation of catalytic activity#GO:0050790;organic substance transport#GO:0071702;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;secretion by cell#GO:0032940;regulation of programmed cell death#GO:0043067;activation of adenylate cyclase activity#GO:0007190;regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;organonitrogen compound metabolic process#GO:1901564;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;multi-organism process#GO:0051704;positive regulation of protein metabolic process#GO:0051247;regulation of cell death#GO:0010941;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;system process#GO:0003008;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;cell population proliferation#GO:0008283;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;activation of phospholipase C activity#GO:0007202;intracellular signal transduction#GO:0035556;multi-organism reproductive process#GO:0044703;positive regulation of biological process#GO:0048518;multicellular organismal reproductive process#GO:0048609;potassium ion transport#GO:0006813;organic substance metabolic process#GO:0071704;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;macromolecule metabolic process#GO:0043170;positive regulation of secretion#GO:0051047;sensory perception of pain#GO:0019233;positive regulation of transport#GO:0051050;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;sexual reproduction#GO:0019953;positive regulation of catabolic process#GO:0009896;regulation of ion transport#GO:0043269;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of protein catabolic process#GO:0045732;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;blood circulation#GO:0008015;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;macromolecule localization#GO:0033036;regulation of cyclase activity#GO:0031279;transport#GO:0006810;endothelial cell proliferation#GO:0001935;positive regulation of metabolic process#GO:0009893;regulation of transport#GO:0051049;negative regulation of cell population proliferation#GO:0008285;metabolic process#GO:0008152;monovalent inorganic cation transport#GO:0015672;regulation of apoptotic process#GO:0042981;multicellular organism reproduction#GO:0032504;ion transport#GO:0006811;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;sensory perception#GO:0007600;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuronal cell body#GO:0043025;neuron projection#GO:0043005;perikaryon#GO:0043204;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 neuropeptide#PC00162 HUMAN|HGNC=16265|UniProtKB=Q9H1J7 Q9H1J7 WNT5B PTHR12027:SF87 WNT RELATED PROTEIN WNT-5B receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=3350|UniProtKB=P06733 P06733 ENO1 PTHR11902:SF12 ENOLASE ALPHA-ENOLASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ATP generation from ADP#GO:0006757;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organelle fusion#GO:0048284;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;ADP metabolic process#GO:0046031;regulation of organelle organization#GO:0033043;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;vacuole fusion, non-autophagic#GO:0042144;regulation of cellular process#GO:0050794;glycolytic process#GO:0006096;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular#GO:0005622 lyase#PC00144 Glycolysis#P00024>Enolase#P00678 HUMAN|HGNC=34346|UniProtKB=A7E2U8 A7E2U8 C4orf47 PTHR31144:SF1 UPF0602 PROTEIN C4ORF47 UPF0602 PROTEIN C4ORF47 HUMAN|HGNC=11350|UniProtKB=P78524 P78524 DENND2B PTHR15288:SF5 SUPPRESSION OF TUMORIGENICITY 5 ST5 DENN DOMAIN-CONTAINING PROTEIN 2B Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;ERK1 and ERK2 cascade#GO:0070371;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 HUMAN|HGNC=9706|UniProtKB=Q15223 Q15223 NECTIN1 PTHR23277:SF69 NECTIN-RELATED NECTIN-1 localization#GO:0051179;macromolecule localization#GO:0033036;protein localization to cell junction#GO:1902414;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha C-terminal fragment#P00177;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha N-terminal fragment#P00164;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha intracellular fragment#P00159;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha#P00160;Alzheimer disease-presenilin pathway#P00004>Nectin 1alpha transmembrane fragment#P00134 HUMAN|HGNC=11568|UniProtKB=Q13395 Q13395 TARBP1 PTHR12029:SF11 RNA METHYLTRANSFERASE METHYLTRANSFERASE TARBP1-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA methyltransferase#PC00033 HUMAN|HGNC=7157|UniProtKB=P24347 P24347 MMP11 PTHR10201:SF20 MATRIX METALLOPROTEINASE STROMELYSIN-3 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 HUMAN|HGNC=20224|UniProtKB=Q96JK2 Q96JK2 DCAF5 PTHR15574:SF43 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 5 lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of lipid biosynthetic process#GO:0046890;negative regulation of cellular process#GO:0048523;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;negative regulation of biosynthetic process#GO:0009890;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;fatty acid metabolic process#GO:0006631;regulation of cellular biosynthetic process#GO:0031326;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=24624|UniProtKB=Q9H173 Q9H173 SIL1 PTHR19316:SF32 PROTEIN FOLDING REGULATOR NUCLEOTIDE EXCHANGE FACTOR SIL1 HUMAN|HGNC=20743|UniProtKB=Q96KN4 Q96KN4 LRATD1 PTHR46341:SF1 PROTEIN FAM84B-RELATED PROTEIN LRATD1 HUMAN|HGNC=28589|UniProtKB=Q8TB03 Q8TB03 CXorf38 PTHR35083:SF1 RGD1565685 PROTEIN RGD1565685 PROTEIN HUMAN|HGNC=28623|UniProtKB=Q96PS1 Q96PS1 FANCD2OS PTHR31036:SF0 FANCD2 OPPOSITE STRAND PROTEIN FANCD2 OPPOSITE STRAND PROTEIN HUMAN|HGNC=3569|UniProtKB=P33121 P33121 ACSL1 PTHR43272:SF28 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 1 ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;very long-chain fatty acid metabolic process#GO:0000038;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;organic acid metabolic process#GO:0006082;fatty acid derivative metabolic process#GO:1901568;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;fatty acid metabolic process#GO:0006631;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 ligase#PC00142 HUMAN|HGNC=17378|UniProtKB=Q9UK23 Q9UK23 NAGPA PTHR40446:SF2 N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;peptide secretion#GO:0002790;cellular process#GO:0009987;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 HUMAN|HGNC=19764|UniProtKB=Q5TA89 Q5TA89 HES5 PTHR10985:SF104 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 HUMAN|HGNC=676|UniProtKB=O43182 O43182 ARHGAP6 PTHR12635:SF6 RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER RHO GTPASE-ACTIVATING PROTEIN 6 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;phospholipase activity#GO:0004620;enzyme regulator activity#GO:0030234 positive regulation of lipase activity#GO:0060193;regulation of lipase activity#GO:0060191;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;biological regulation#GO:0065007;positive regulation of phospholipase activity#GO:0010518;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345;positive regulation of phospholipase C activity#GO:0010863 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=15220|UniProtKB=Q8NGK6 Q8NGK6 OR52I1 PTHR26450:SF177 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52I1-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=25143|UniProtKB=Q86UD5 Q86UD5 SLC9B2 PTHR31102:SF14 FAMILY NOT NAMED SODIUM/HYDROGEN EXCHANGER 9B2 localization#GO:0051179;cation transport#GO:0006812;monovalent inorganic cation transport#GO:0015672;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810 HUMAN|HGNC=9509|UniProtKB=P49810 P49810 PSEN2 PTHR10202:SF24 PRESENILIN PRESENILIN-2 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 negative regulation of biological process#GO:0048519;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;cation transport#GO:0006812;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;negative regulation of programmed cell death#GO:0043069;proteolysis#GO:0006508;apoptotic process#GO:0006915;cell death#GO:0008219;divalent inorganic cation transport#GO:0072511;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;membrane protein proteolysis#GO:0033619;metal ion transport#GO:0030001;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular nitrogen compound metabolic process#GO:0034641;membrane protein ectodomain proteolysis#GO:0006509;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;localization#GO:0051179;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cellular amide metabolic process#GO:0043603 bounding membrane of organelle#GO:0098588;supramolecular complex#GO:0099080;synapse#GO:0045202;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;apical plasma membrane#GO:0016324;non-membrane-bounded organelle#GO:0043228;intrinsic component of membrane#GO:0031224;lysosome#GO:0005764;mitochondrial envelope#GO:0005740;sarcomere#GO:0030017;distal axon#GO:0150034;plasma membrane region#GO:0098590;envelope#GO:0031975;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;vacuolar membrane#GO:0005774;organelle inner membrane#GO:0019866;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;dendritic tree#GO:0097447;contractile fiber#GO:0043292;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;lytic vacuole membrane#GO:0098852;mitochondrial inner membrane#GO:0005743;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;cell surface#GO:0009986;intracellular#GO:0005622;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cilium#GO:0005929;myofibril#GO:0030016;membrane microdomain#GO:0098857;membrane region#GO:0098589;neuromuscular junction#GO:0031594;intraciliary transport particle#GO:0030990;somatodendritic compartment#GO:0036477;Z disc#GO:0030018;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;mitochondrion#GO:0005739;cell cortex#GO:0005938;lytic vacuole#GO:0000323;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;whole membrane#GO:0098805;protein-containing complex#GO:0032991;cell body#GO:0044297;integral component of plasma membrane#GO:0005887;membrane raft#GO:0045121;growth cone#GO:0030426;site of polarized growth#GO:0030427;I band#GO:0031674 aspartic protease#PC00053 Notch signaling pathway#P00045>Pen-2#P01113;Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098 HUMAN|HGNC=26076|UniProtKB=Q9NWR8 Q9NWR8 MCUB PTHR13462:SF6 CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL CALCIUM UNIPORTER REGULATORY SUBUNIT MCUB, MITOCHONDRIAL calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;calcium channel regulator activity#GO:0005246;secondary active transmembrane transporter activity#GO:0015291;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;mitochondrial calcium ion homeostasis#GO:0051560;mitochondrial transmembrane transport#GO:1990542;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;mitochondrial transport#GO:0006839;cellular chemical homeostasis#GO:0055082;mitochondrial calcium ion transmembrane transport#GO:0006851;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 integral component of mitochondrial inner membrane#GO:0031305;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intrinsic component of mitochondrial inner membrane#GO:0031304;ion channel complex#GO:0034702;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;membrane#GO:0016020;cation channel complex#GO:0034703;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of mitochondrial membrane#GO:0098573;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=7643|UniProtKB=O43776 O43776 NARS1 PTHR22594:SF16 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINE--TRNA LIGASE, CYTOPLASMIC aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=30779|UniProtKB=Q49AM1 Q49AM1 MTERF2 PTHR15437:SF1 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR 2, MITOCHONDRIAL nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 General transcription regulation#P00023>TTF2#P00661;Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 HUMAN|HGNC=24041|UniProtKB=Q86V24 Q86V24 ADIPOR2 PTHR20855:SF33 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>AdipoR1/R2#P06706 HUMAN|HGNC=3685|UniProtKB=P21781 P21781 FGF7 PTHR11486:SF20 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 7 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;gene expression#GO:0010467;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;positive regulation of protein modification process#GO:0031401;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;peptidyl-tyrosine phosphorylation#GO:0018108;epithelial cell proliferation#GO:0050673;positive regulation of epithelial cell proliferation#GO:0050679;cellular protein metabolic process#GO:0044267;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;taxis#GO:0042330;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;regulation of locomotion#GO:0040012;RNA metabolic process#GO:0016070;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of protein metabolic process#GO:0051247;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;tube development#GO:0035295;RNA biosynthetic process#GO:0032774;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;movement of cell or subcellular component#GO:0006928;aromatic compound biosynthetic process#GO:0019438;positive chemotaxis#GO:0050918;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;animal organ development#GO:0048513;developmental process#GO:0032502;peptidyl-amino acid modification#GO:0018193;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular macromolecule biosynthetic process#GO:0034645;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;peptidyl-tyrosine modification#GO:0018212;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=17575|UniProtKB=Q96T58 Q96T58 SPEN PTHR23189:SF48 RNA RECOGNITION MOTIF-CONTAINING MSX2-INTERACTING PROTEIN nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=27364|UniProtKB=A8MVW5 A8MVW5 HEPACAM2 PTHR44888:SF1 HEPACAM FAMILY MEMBER 2-RELATED HEPACAM FAMILY MEMBER 2 HUMAN|HGNC=8768|UniProtKB=O95831 O95831 AIFM1 PTHR43557:SF4 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL oxidoreductase#PC00176 Apoptosis signaling pathway#P00006>AIF#P00286 HUMAN|HGNC=11458|UniProtKB=Q06520 Q06520 SULT2A1 PTHR11783:SF8 SULFOTRANSFERASE SULT BILE SALT SULFOTRANSFERASE transferase#PC00220 HUMAN|HGNC=1383|UniProtKB=Q16790 Q16790 CA9 PTHR18952:SF18 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 9 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=15173|UniProtKB=Q8NGI6 Q8NGI6 OR4D10 PTHR48002:SF68 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D10 transmembrane signal receptor#PC00197 HUMAN|HGNC=14082|UniProtKB=Q9NQW6 Q9NQW6 ANLN PTHR21538:SF23 ANILLIN/RHOTEKIN RTKN ANILLIN Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;GTP-Rho binding#GO:0017049;Rho GTPase binding#GO:0017048 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell division#GO:0051301;actomyosin contractile ring organization#GO:0044837;membrane fission#GO:0090148;assembly of actomyosin apparatus involved in cytokinesis#GO:0000912;membrane organization#GO:0061024;septin ring organization#GO:0031106;actomyosin contractile ring assembly#GO:0000915;nuclear division#GO:0000280;cell cycle process#GO:0022402;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cytokinesis#GO:0000910;cortical actin cytoskeleton organization#GO:0030866;septin cytoskeleton organization#GO:0032185 actomyosin contractile ring#GO:0005826;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cell division site#GO:0032153;contractile ring#GO:0070938;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 HUMAN|HGNC=2180|UniProtKB=O43405 O43405 COCH PTHR24020:SF36 COLLAGEN ALPHA COCHLIN extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=15972|UniProtKB=Q9P253 Q9P253 VPS18 PTHR23323:SF26 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG protein binding#GO:0005515;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;endosome organization#GO:0007032;vacuole organization#GO:0007033;regulation of transport#GO:0051049;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;secretion#GO:0046903;vesicle organization#GO:0016050;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;export from cell#GO:0140352 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=28615|UniProtKB=Q5H9R4 Q5H9R4 ARMCX4 PTHR47081:SF1 FAMILY NOT NAMED ARMADILLO REPEAT-CONTAINING X-LINKED PROTEIN 4 HUMAN|HGNC=5047|UniProtKB=O43390 O43390 HNRNPR PTHR21245:SF5 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN R nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=11768|UniProtKB=P61812 P61812 TGFB2 PTHR11848:SF141 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-2 PROPROTEIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>TGFbeta#P06778 HUMAN|HGNC=8921|UniProtKB=Q92576 Q92576 PHF3 PTHR11477:SF10 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN PHD FINGER PROTEIN 3 general transcription factor#PC00259 HUMAN|HGNC=7774|UniProtKB=O94916 O94916 NFAT5 PTHR12533:SF10 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772 positive regulation of gene expression#GO:0010628;calcium-mediated signaling#GO:0019722;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851 HUMAN|HGNC=30811|UniProtKB=A8K4G0 A8K4G0 CD300LB PTHR11860:SF103 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 7 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=4477|UniProtKB=Q99680 Q99680 GPR22 PTHR24241:SF1 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 22 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=4478|UniProtKB=Q99677 Q99677 LPAR4 PTHR24232:SF41 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 4 carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;binding#GO:0005488;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;phospholipid binding#GO:0005543;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=18144|UniProtKB=Q8IZU8 Q8IZU8 DSEL PTHR15532:SF2 FAMILY NOT NAMED DERMATAN-SULFATE EPIMERASE-LIKE PROTEIN isomerase activity#GO:0016853;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;proteoglycan metabolic process#GO:0006029;chondroitin sulfate metabolic process#GO:0030204;chondroitin sulfate proteoglycan metabolic process#GO:0050654;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 HUMAN|HGNC=19607|UniProtKB=Q8NH19 Q8NH19 OR10AG1 PTHR26453:SF159 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10AG1 transmembrane signal receptor#PC00197 HUMAN|Ensembl=ENSG00000262179|UniProtKB=A0A1B0GTQ4 A0A1B0GTQ4 MYMX PTHR41686:SF1 MYOMIXER PROTEIN MYOMIXER skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;plasma membrane fusion#GO:0045026;muscle organ development#GO:0007517;muscle cell differentiation#GO:0042692;membrane organization#GO:0061024;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-cell fusion#GO:0140253;anatomical structure formation involved in morphogenesis#GO:0048646;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;system development#GO:0048731;syncytium formation by plasma membrane fusion#GO:0000768;membrane fusion#GO:0061025;syncytium formation#GO:0006949;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=26094|UniProtKB=Q7L4S7 Q7L4S7 ARMCX6 PTHR15712:SF6 ARMADILLO REPEAT CONTAINING PROTEIN PROTEIN ARMCX6 HUMAN|HGNC=18799|UniProtKB=Q99766 Q99766 DMAC2L PTHR13382:SF10 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B ATP SYNTHASE SUBUNIT S, MITOCHONDRIAL ATP synthase#PC00002 HUMAN|HGNC=28449|UniProtKB=C9JLR9 C9JLR9 C11orf95 PTHR34589:SF2 SIMILAR TO RIKEN CDNA 2700081O15 SIMILAR TO RIKEN CDNA 2700081O15 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=429|UniProtKB=P18054 P18054 ALOX12 PTHR11771:SF4 LIPOXYGENASE POLYUNSATURATED FATTY ACID LIPOXYGENASE ALOX12 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;oxidation-reduction process#GO:0055114;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxygenase#PC00177 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 HUMAN|HGNC=16445|UniProtKB=Q96LJ7 Q96LJ7 DHRS1 PTHR44147:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 dehydrogenase#PC00092 HUMAN|HGNC=4879|UniProtKB=P07686 P07686 HEXB PTHR22600:SF38 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE SUBUNIT BETA glycosidase#PC00110 HUMAN|HGNC=20983|UniProtKB=Q8N987 Q8N987 NECAB1 PTHR12178:SF11 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 1 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;regulation of primary metabolic process#GO:0080090;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=24766|UniProtKB=Q6ZVE7 Q6ZVE7 GOLT1A PTHR21493:SF245 CGI-141-RELATED/LIPASE CONTAINING PROTEIN VESICLE TRANSPORT PROTEIN GOT1A cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 lipase#PC00143 HUMAN|Ensembl=ENSG00000281759|UniProtKB=A0A0G2JRQ6 A0A0G2JRQ6 ENSG00000281759 PTHR23267:SF216 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=1306|UniProtKB=O15442 O15442 MPPED1 PTHR12905:SF31 METALLOPHOSPHOESTERASE METALLOPHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN 1 esterase#PC00097 HUMAN|HGNC=28653|UniProtKB=Q96IK0 Q96IK0 TMEM101 PTHR31034:SF2 TRANSMEMBRANE PROTEIN 101 TRANSMEMBRANE PROTEIN 101 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 HUMAN|HGNC=12016|UniProtKB=P29144 P29144 TPP2 PTHR43806:SF14 PEPTIDASE S8 TRIPEPTIDYL-PEPTIDASE 2 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 serine protease#PC00203 HUMAN|HGNC=613|UniProtKB=P02649 P02649 APOE PTHR18976:SF2 APOLIPOPROTEIN APOLIPOPROTEIN E sterol metabolic process#GO:0016125;neuron apoptotic process#GO:0051402;lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;regulation of neuron death#GO:1901214;protein catabolic process#GO:0030163;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;cholesterol metabolic process#GO:0008203;neuron death#GO:0070997;lipid catabolic process#GO:0016042;regulation of catalytic activity#GO:0050790;negative regulation of neuron death#GO:1901215;regulation of biological process#GO:0050789;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;cell death#GO:0008219;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;secondary alcohol metabolic process#GO:1902652;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;steroid catabolic process#GO:0006706;macromolecule catabolic process#GO:0009057;regulation of multicellular organismal process#GO:0051239;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;programmed cell death#GO:0012501;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;negative regulation of cell death#GO:0060548;small molecule catabolic process#GO:0044282;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;organic cyclic compound catabolic process#GO:1901361;multicellular organismal process#GO:0032501;lipoprotein metabolic process#GO:0042157;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576 apolipoprotein#PC00052 HUMAN|HGNC=877|UniProtKB=P49419 P49419 ALDH7A1 PTHR43521:SF5 ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=8498|UniProtKB=P02763 P02763 ORM1 PTHR11967:SF2 ALPHA-1-ACID GLYCOPROTEIN ALPHA-1-ACID GLYCOPROTEIN 1 HUMAN|HGNC=4748|UniProtKB=Q99880 Q99880 H2BC13 PTHR23428:SF190 HISTONE H2B HISTONE H2B TYPE 1-L nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=31940|UniProtKB=P0C7N8 P0C7N8 OR9G9 PTHR24242:SF158 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 9G1-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=51246|UniProtKB=B9A6J9 B9A6J9 TBC1D3L PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=9872|UniProtKB=Q15283 Q15283 RASA2 PTHR10194:SF21 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 2 GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646 HUMAN|HGNC=3188|UniProtKB=O75530 O75530 EED PTHR10253:SF5 POLYCOMB PROTEIN POLYCOMB PROTEIN EED N-methyltransferase activity#GO:0008170;nucleosome binding#GO:0031491;binding#GO:0005488;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;chromatin binding#GO:0003682;transferase activity, transferring one-carbon groups#GO:0016741;protein-containing complex binding#GO:0044877;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=28695|UniProtKB=Q8N1A0 Q8N1A0 KRT222 PTHR47082:SF1 KERATIN-LIKE PROTEIN KRT222 KERATIN-LIKE PROTEIN KRT222 HUMAN|HGNC=29534|UniProtKB=Q9BSJ8 Q9BSJ8 ESYT1 PTHR45761:SF3 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-1 HUMAN|HGNC=7853|UniProtKB=P56597 P56597 NME5 PTHR46161:SF1 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE HOMOLOG 5 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;response to oxidative stress#GO:0006979;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to oxidative stress#GO:0034599;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of response to stress#GO:0080134;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;negative regulation of cell death#GO:0060548;intrinsic apoptotic signaling pathway#GO:0097193;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of intrinsic apoptotic signaling pathway#GO:2001242;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo purine biosynthesis#P02738>GDP kinase#P02891 HUMAN|HGNC=292|UniProtKB=P30520 P30520 ADSS2 PTHR11846:SF13 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;AMP metabolic process#GO:0046033;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 HUMAN|HGNC=20651|UniProtKB=Q8NCC5 Q8NCC5 SLC37A3 PTHR43184:SF12 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B SUGAR PHOSPHATE EXCHANGER 3 transporter#PC00227 HUMAN|HGNC=6086|UniProtKB=P51460 P51460 INSL3 PTHR10423:SF6 INSULIN-LIKE 3 INSULIN-LIKE 3 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;second-messenger-mediated signaling#GO:0019932;negative regulation of intracellular signal transduction#GO:1902532;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=24073|UniProtKB=Q86SJ2 Q86SJ2 AMIGO2 PTHR24368:SF209 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 2 head development#GO:0060322;system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;brain development#GO:0007420;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=1243|UniProtKB=Q07021 Q07021 C1QBP PTHR10826:SF1 COMPLEMENT COMPONENT 1 COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;positive regulation of cellular protein metabolic process#GO:0032270;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6452|UniProtKB=O76011 O76011 KRT34 PTHR23239:SF165 INTERMEDIATE FILAMENT IF ROD DOMAIN-CONTAINING PROTEIN-RELATED HUMAN|HGNC=14913|UniProtKB=Q9NYW3 Q9NYW3 TAS2R7 PTHR11394:SF58 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=26762|UniProtKB=Q8N998 Q8N998 CCDC89 PTHR34768:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 89 COILED-COIL DOMAIN-CONTAINING PROTEIN 89 HUMAN|HGNC=33823|UniProtKB=P60508 P60508 ERVFRD-1 PTHR10424:SF66 VIRAL ENVELOPE PROTEIN SYNCYTIN-2 cellular component organization or biogenesis#GO:0071840;plasma membrane fusion#GO:0045026;syncytium formation by plasma membrane fusion#GO:0000768;membrane fusion#GO:0061025;syncytium formation#GO:0006949;anatomical structure morphogenesis#GO:0009653;membrane organization#GO:0061024;anatomical structure development#GO:0048856;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-cell fusion#GO:0140253;anatomical structure formation involved in morphogenesis#GO:0048646 viral or transposable element protein#PC00237 HUMAN|HGNC=4411|UniProtKB=P63211 P63211 GNGT1 PTHR13809:SF26 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT GAMMA-T1 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 PI3 kinase pathway#P00048>Gbetagamma#P01188;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 HUMAN|HGNC=3386|UniProtKB=P29317 P29317 EPHA2 PTHR24416:SF306 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=5465|UniProtKB=P08069 P08069 IGF1R PTHR24416:SF106 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;peptide hormone binding#GO:0017046;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;JNK cascade#GO:0007254;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;inositol lipid-mediated signaling#GO:0048017;protein kinase B signaling#GO:0043491;positive regulation of protein kinase B signaling#GO:0051897;multicellular organismal process#GO:0032501;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;phosphatidylinositol-mediated signaling#GO:0048015;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;chemical homeostasis#GO:0048878;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;phosphatidylinositol 3-kinase signaling#GO:0014065;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of phosphatidylinositol 3-kinase signaling#GO:0014066;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of protein kinase B signaling#GO:0051896;regulation of transferase activity#GO:0051338 membrane protein complex#GO:0098796;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;integral component of membrane#GO:0016021;axon#GO:0030424;transferase complex, transferring phosphorus-containing groups#GO:0061695;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Gonadotropin-releasing hormone receptor pathway#P06664>IGF-1R#P06703 HUMAN|HGNC=32233|UniProtKB=Q8NAV2 Q8NAV2 C8orf58 PTHR37336:SF1 SIMILAR TO 9930012K11RIK PROTEIN DUF4657 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=12955|UniProtKB=Q9P0L1 Q9P0L1 ZKSCAN7 PTHR24377:SF882 IP01015P-RELATED ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=23360|UniProtKB=Q8N163 Q8N163 CCAR2 PTHR14304:SF12 CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN CELL CYCLE AND APOPTOSIS REGULATOR PROTEIN 2 transcription coregulator activity#GO:0003712;basal RNA polymerase II transcription machinery binding#GO:0001099;transcription regulator activity#GO:0140110;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;transcription coactivator activity#GO:0003713;RNA polymerase II complex binding#GO:0000993;enzyme binding#GO:0019899;nuclear receptor transcription coactivator activity#GO:0030374;protein binding#GO:0005515;molecular function regulator#GO:0098772;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=28287|UniProtKB=Q96F25 Q96F25 ALG14 PTHR12154:SF4 GLYCOSYL TRANSFERASE-RELATED UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 HOMOLOG glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;cellular lipid metabolic process#GO:0044255;cellular protein metabolic process#GO:0044267;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=20877|UniProtKB=Q9H7R0 Q9H7R0 ZNF442 PTHR24379:SF6 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 442 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20821|UniProtKB=Q17RW2 Q17RW2 COL24A1 PTHR24023:SF987 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXIV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=1994|UniProtKB=P06732 P06732 CKM PTHR11547:SF63 ARGININE OR CREATINE KINASE CREATINE KINASE M-TYPE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 amino acid kinase#PC00045 HUMAN|HGNC=18358|UniProtKB=Q8NAC3 Q8NAC3 IL17RC PTHR15583:SF12 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR C signaling receptor activity#GO:0038023;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;cytokine binding#GO:0019955 transmembrane signal receptor#PC00197 HUMAN|HGNC=10541|UniProtKB=Q01826 Q01826 SATB1 PTHR15116:SF14 DNA-BINDING PROTEIN SATB FAMILY MEMBER DNA-BINDING PROTEIN SATB1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 Lambda repressor-like transcription factor#PC00245 HUMAN|HGNC=9486|UniProtKB=P35030 P35030 PRSS3 PTHR24264:SF48 TRYPSIN-RELATED TRYPSIN-3 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=21806|UniProtKB=Q8N393 Q8N393 ZNF786 PTHR24376:SF185 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 786 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=18396|UniProtKB=O95969 O95969 SCGB1D2 PTHR11332:SF10 SECRETOGLOBIN FAMILY 1D SECRETOGLOBIN FAMILY 1D MEMBER 2 transfer/carrier protein#PC00219 HUMAN|HGNC=35159|UniProtKB=A8MTL0 A8MTL0 IQCF5 PTHR21633:SF24 IQ MOTIF CONTAINING F IQ DOMAIN-CONTAINING PROTEIN F5 protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 HUMAN|HGNC=23624|UniProtKB=Q8TDV0 Q8TDV0 GPR151 PTHR45695:SF1 LEUCOKININ RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 151 transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin#P00747 HUMAN|HGNC=30739|UniProtKB=Q9Y320 Q9Y320 TMX2 PTHR15853:SF0 THIOREDOXIN-RELATED THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 2 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176 HUMAN|HGNC=23916|UniProtKB=A6NEQ0 A6NEQ0 RBMY1E PTHR24012:SF685 RNA BINDING PROTEIN RNA-BINDING MOTIF PROTEIN, Y CHROMOSOME, FAMILY 1 MEMBER C-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=15938|UniProtKB=Q9NWZ5 Q9NWZ5 UCKL1 PTHR10285:SF68 URIDINE KINASE URIDINE-CYTIDINE KINASE-LIKE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149 HUMAN|HGNC=30571|UniProtKB=Q96I27 Q96I27 ZNF625 PTHR24379:SF107 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 625-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20577|UniProtKB=Q6V0L0 Q6V0L0 CYP26C1 PTHR24286:SF100 CYTOCHROME P450 26 CYTOCHROME P450 26C1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;oxidation-reduction process#GO:0055114;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177 HUMAN|HGNC=5135|UniProtKB=P35452 P35452 HOXD12 PTHR46440:SF1 HOMEOBOX PROTEIN HOX-D12-RELATED HOMEOBOX PROTEIN HOX-D12 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 homeodomain transcription factor#PC00119 HUMAN|HGNC=6735|UniProtKB=P07948 P07948 LYN PTHR24418:SF42 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE LYN protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell population proliferation#GO:0008283;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;innate immune response#GO:0045087;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;peptidyl-tyrosine modification#GO:0018212;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 Cadherin signaling pathway#P00012>Yes#P00476;Parkinson disease#P00049>Src kinase#P01230;B cell activation#P00010>Lyn#P00374;CCKR signaling map#P06959>LYN#P07141 HUMAN|HGNC=19846|UniProtKB=Q86TY3 Q86TY3 ARMH4 PTHR21585:SF0 FULL-LENGTH CDNA CLONE CS0DC025YL05 OF NEUROBLASTOMA ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=691|UniProtKB=O14813 O14813 PHOX2A PTHR24329:SF303 HOMEOBOX PROTEIN ARISTALESS PAIRED MESODERM HOMEOBOX PROTEIN 2A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=18898|UniProtKB=Q9BYR0 Q9BYR0 KRTAP4-7 PTHR23262:SF223 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-6-RELATED HUMAN|HGNC=16040|UniProtKB=Q96DT6 Q96DT6 ATG4C PTHR22624:SF38 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4C cysteine protease#PC00081 HUMAN|HGNC=28028|UniProtKB=Q5VV52 Q5VV52 ZNF691 PTHR24404:SF47 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 691 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11141|UniProtKB=O76070 O76070 SNCG PTHR13820:SF10 SYNUCLEIN GAMMA-SYNUCLEIN cation binding#GO:0043169;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;transition metal ion binding#GO:0046914 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;regulation of neuron death#GO:1901214;membrane organization#GO:0061024;transport#GO:0006810;neuron death#GO:0070997;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;cell death#GO:0008219;synaptic signaling#GO:0099536;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of cell death#GO:0010941;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;cytoplasm#GO:0005737;axon terminus#GO:0043679;cell body#GO:0044297;intracellular#GO:0005622;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cell projection#GO:0042995;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Parkinson disease#P00049>gamma-Synuclein#P01231 HUMAN|HGNC=25272|UniProtKB=Q8TBB5 Q8TBB5 KLHDC4 PTHR46063:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=6637|UniProtKB=P20700 P20700 LMNB1 PTHR45721:SF3 LAMIN DM0-RELATED LAMIN-B1 FAS signaling pathway#P00020>Nuclear Lamin#P00616 HUMAN|HGNC=8296|UniProtKB=P0C645 P0C645 OR4E1 PTHR26451:SF233 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 4E1 HUMAN|HGNC=10967|UniProtKB=O75751 O75751 SLC22A3 PTHR24064:SF52 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 3 secondary carrier transporter#PC00258 HUMAN|HGNC=15285|UniProtKB=Q8NGL1 Q8NGL1 OR5D18 PTHR48018:SF121 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D18 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=13301|UniProtKB=Q9BZJ7 Q9BZJ7 GPR62 PTHR22752:SF11 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 62 G-protein coupled receptor#PC00021 HUMAN|HGNC=26812|UniProtKB=Q8NAG6 Q8NAG6 ANKLE1 PTHR46427:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=16800|UniProtKB=Q685J3 Q685J3 MUC17 PTHR37999:SF1 MUCIN-17 MUCIN-17 HUMAN|HGNC=25784|UniProtKB=Q5H9S7 Q5H9S7 DCAF17 PTHR14815:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 17 DDB1- AND CUL4-ASSOCIATED FACTOR 17 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 HUMAN|HGNC=27080|UniProtKB=A6NFU8 A6NFU8 PGPEP1L PTHR23402:SF15 PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED PYROGLUTAMYL-PEPTIDASE 1-LIKE PROTEIN macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cysteine protease#PC00081 HUMAN|HGNC=20620|UniProtKB=Q5GJ75 Q5GJ75 TNFAIP8L3 PTHR12757:SF5 TUMOR NECROSIS FACTOR INDUCED PROTEIN TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=27111|UniProtKB=Q86VR7 Q86VR7 VSIG10L PTHR44427:SF5 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE HUMAN|HGNC=739|UniProtKB=Q99929 Q99929 ASCL2 PTHR13935:SF62 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;generation of neurons#GO:0048699;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=5187|UniProtKB=Q99873 Q99873 PRMT1 PTHR11006:SF54 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 HUMAN|HGNC=4380|UniProtKB=Q03113 Q03113 GNA12 PTHR10218:SF130 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-12 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;regulation of adenylate cyclase activity#GO:0045761;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;Rho protein signal transduction#GO:0007266;small GTPase mediated signal transduction#GO:0007264;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoplasmic side of membrane#GO:0098562;microvillus#GO:0005902;membrane protein complex#GO:0098796;leaflet of membrane bilayer#GO:0097478;brush border#GO:0005903;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;cluster of actin-based cell projections#GO:0098862;catalytic complex#GO:1902494;cell projection membrane#GO:0031253;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;side of membrane#GO:0098552;polymeric cytoskeletal fiber#GO:0099513;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;cytoskeleton#GO:0005856;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 HUMAN|HGNC=1982|UniProtKB=Q14011 Q14011 CIRBP PTHR48034:SF5 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED COLD-INDUCIBLE RNA-BINDING PROTEIN positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;positive regulation of RNA metabolic process#GO:0051254;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=26363|UniProtKB=Q86YJ7 Q86YJ7 ANKRD13B PTHR12447:SF3 UNCHARACTERIZED WITH ANKYRIN REPEAT DOMAIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13B cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=33865|UniProtKB=Q6ZT21 Q6ZT21 TMPPE PTHR31302:SF0 TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN-RELATED TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN HUMAN|HGNC=795|UniProtKB=Q13315 Q13315 ATM PTHR11139:SF72 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE-PROTEIN KINASE ATM transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stress#GO:0006950;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;DNA integrity checkpoint#GO:0031570;telomere organization#GO:0032200;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;telomere maintenance#GO:0000723;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;cell death#GO:0008219;DNA damage checkpoint#GO:0000077;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;TORC1 signaling#GO:0038202;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;homeostatic process#GO:0042592;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 p53 pathway feedback loops 2#P04398>ATM#P04669;p53 pathway#P00059>ATM/ATR#P01481 HUMAN|HGNC=933|UniProtKB=P56817 P56817 BACE1 PTHR47965:SF69 ASPARTYL PROTEASE-RELATED BETA-SECRETASE 1 membrane protein proteolysis#GO:0033619;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein metabolic process#GO:0019538;membrane protein ectodomain proteolysis#GO:0006509;primary metabolic process#GO:0044238;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>BACE-1#P00101;Alzheimer disease-amyloid secretase pathway#P00003>Pro-BACE-1#P00081;Alzheimer disease-presenilin pathway#P00004>BACE-1#P00172;Alzheimer disease-presenilin pathway#P00004>BACE-1 pro-domain#P00178;Alzheimer disease-presenilin pathway#P00004>Pro-BACE-1#P00162;Alzheimer disease-amyloid secretase pathway#P00003>BACE-1 pro-domain#P00094 HUMAN|HGNC=1938|UniProtKB=Q9Y259 Q9Y259 CHKB PTHR22603:SF35 CHOLINE/ETHANOALAMINE KINASE CHOLINE/ETHANOLAMINE KINASE kinase#PC00137 HUMAN|HGNC=3133|UniProtKB=Q15125 Q15125 EBP PTHR14207:SF0 STEROL ISOMERASE 3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 isomerase#PC00135 HUMAN|HGNC=26282|UniProtKB=Q8N4S0 Q8N4S0 CCDC82 PTHR14689:SF0 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 82 HUMAN|HGNC=32271|UniProtKB=A8MXZ1 A8MXZ1 FAM90A23P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=41908|UniProtKB=Q8TEE9 Q8TEE9 SAP25 PTHR39231:SF1 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP25 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP25 histone modifying enzyme#PC00261 HUMAN|HGNC=24085|UniProtKB=Q9Y5M8 Q9Y5M8 SRPRB PTHR11485:SF34 TRANSFERRIN SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT BETA cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 transfer/carrier protein#PC00219 HUMAN|HGNC=9393|UniProtKB=P17252 P17252 PRKCA PTHR24356:SF193 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C ALPHA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>PKC#P00565;CCKR signaling map#P06959>PKCalpha#P07095;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Apoptosis signaling pathway#P00006>PKCs#P00318;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PKC#P05942;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs(3)#P06850;PDGF signaling pathway#P00047>PKC#P01150;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 HUMAN|HGNC=4733|UniProtKB=Q93077 Q93077 H2AC6 PTHR23430:SF28 HISTONE H2A HISTONE H2A TYPE 1-C heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=29459|UniProtKB=Q5T7P2 Q5T7P2 LCE1A PTHR23263:SF144 SMALL PROLINE-RICH PROTEIN LATE CORNIFIED ENVELOPE PROTEIN 1A HUMAN|HGNC=13706|UniProtKB=Q9P2T0 Q9P2T0 THEG PTHR15901:SF16 TESTICULAR HAPLOID EXPRESSED GENE PROTEIN TESTICULAR HAPLOID EXPRESSED GENE PROTEIN HUMAN|HGNC=16628|UniProtKB=Q96SL1 Q96SL1 SLC49A4 PTHR10924:SF27 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED SOLUTE CARRIER FAMILY 49 MEMBER 4 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=13680|UniProtKB=Q96JB8 Q96JB8 MPP4 PTHR23122:SF34 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 4 scaffold/adaptor protein#PC00226 HUMAN|HGNC=5433|UniProtKB=P48551 P48551 IFNAR2 PTHR20859:SF84 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON ALPHA/BETA RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=1406|UniProtKB=Q9Y698 Q9Y698 CACNG2 PTHR12107:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-2 SUBUNIT calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;cation channel activity#GO:0005261;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 cellular localization#GO:0051641;membrane organization#GO:0061024;system process#GO:0003008;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;anterograde trans-synaptic signaling#GO:0098916;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;regulation of transmembrane transporter activity#GO:0022898;positive regulation of signaling#GO:0023056;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;establishment of protein localization to vacuole#GO:0072666;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;protein localization to synapse#GO:0035418;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of ion transmembrane transport#GO:0034765;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein localization to cell junction#GO:1902414;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;regulation of trans-synaptic signaling#GO:0099177;regulation of ion transport#GO:0043269;multicellular organismal process#GO:0032501;protein-containing complex localization#GO:0031503;receptor localization to synapse#GO:0097120;signal transduction#GO:0007165;regulation of neurotransmitter receptor activity#GO:0099601;receptor internalization#GO:0031623;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;action potential#GO:0001508;cation transport#GO:0006812;ionotropic glutamate receptor signaling pathway#GO:0035235;cation transmembrane transport#GO:0098655;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;vacuolar transport#GO:0007034;protein localization to membrane#GO:0072657;regulation of membrane potential#GO:0042391;protein localization to vacuole#GO:0072665;ion transport#GO:0006811;establishment of protein localization to organelle#GO:0072594;regulation of AMPA receptor activity#GO:2000311;nervous system process#GO:0050877;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;protein localization to cell periphery#GO:1990778;localization#GO:0051179;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of synaptic transmission#GO:0050806;synaptic transmission, glutamatergic#GO:0035249 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;organelle#GO:0043226;integral component of membrane#GO:0016021;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>stargazin#P00998 HUMAN|HGNC=51830|UniProtKB=P0DN76 P0DN76 U2AF1L5 PTHR12620:SF11 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT SPLICING FACTOR U2AF 35 KDA SUBUNIT-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=10940|UniProtKB=P43004 P43004 SLC1A2 PTHR11958:SF93 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 2 primary active transporter#PC00068 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 HUMAN|HGNC=30795|UniProtKB=A1L157 A1L157 TSPAN11 PTHR19282:SF198 TETRASPANIN TETRASPANIN-11 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=8508|UniProtKB=O95747 O95747 OXSR1 PTHR48012:SF1 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE/THREONINE-PROTEIN KINASE OSR1 HUMAN|HGNC=16710|UniProtKB=Q9H8T0 Q9H8T0 AKTIP PTHR24068:SF211 UBIQUITIN-CONJUGATING ENZYME E2 AKT-INTERACTING PROTEIN ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=1481|UniProtKB=P04632 P04632 CAPNS1 PTHR46735:SF1 CALPAIN, SMALL SUBUNIT 1 A-RELATED CALPAIN SMALL SUBUNIT 1 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=9940|UniProtKB=Q92781 Q92781 RDH5 PTHR43313:SF12 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 5 dehydrogenase#PC00092 HUMAN|HGNC=13613|UniProtKB=Q969U6 Q969U6 FBXW5 PTHR20995:SF17 F-BOX/WD REPEAT-CONTAINING PROTEIN 5 F-BOX/WD REPEAT-CONTAINING PROTEIN 5 HUMAN|HGNC=30206|UniProtKB=Q5M7Z0 Q5M7Z0 RNFT1 PTHR15860:SF1 UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNFT1 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stress#GO:0006950;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;regulation of response to stress#GO:0080134;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=23627|UniProtKB=Q86SP6 Q86SP6 GPR149 PTHR24229:SF32 NEUROPEPTIDES RECEPTOR G-PROTEIN COUPLED RECEPTOR 149-RELATED neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=7690|UniProtKB=P56556 P56556 NDUFA6 PTHR12964:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6 response to stimulus#GO:0050896;response to stress#GO:0006950;response to oxidative stress#GO:0006979 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=28651|UniProtKB=Q9BRX8 Q9BRX8 PRXL2A PTHR28630:SF3 FAMILY NOT NAMED PEROXIREDOXIN-LIKE 2A HUMAN|HGNC=19165|UniProtKB=O60343 O60343 TBC1D4 PTHR22957:SF195 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 4 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=9251|UniProtKB=P10619 P10619 CTSA PTHR11802:SF254 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE LYSOSOMAL PROTECTIVE PROTEIN catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 serine protease#PC00203 HUMAN|HGNC=12779|UniProtKB=O14905 O14905 WNT9B PTHR12027:SF84 WNT RELATED PROTEIN WNT-9B receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=16512|UniProtKB=Q8WZ55 Q8WZ55 BSND PTHR28399:SF1 BARTTIN BARTTIN inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;molecular function regulator#GO:0098772;chloride transmembrane transporter activity#GO:0015108;channel regulator activity#GO:0016247;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;chloride transport#GO:0006821;establishment of localization#GO:0051234;anion transport#GO:0006820;inorganic anion transport#GO:0015698;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;basolateral plasma membrane#GO:0016323;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=25531|UniProtKB=Q96K12 Q96K12 FAR2 PTHR11011:SF60 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;fatty acid derivative metabolic process#GO:1901568;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;cellular amide metabolic process#GO:0043603;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=59|UniProtKB=Q09428 Q09428 ABCC8 PTHR24223:SF187 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=84|UniProtKB=Q13085 Q13085 ACACA PTHR45728:SF5 ACETYL-COA CARBOXYLASE, ISOFORM A ACETYL-COA CARBOXYLASE 1 HUMAN|HGNC=31104|UniProtKB=Q92614 Q92614 MYO18A PTHR45615:SF13 MYOSIN HEAVY CHAIN, NON-MUSCLE UNCONVENTIONAL MYOSIN-XVIIIA Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=1699|UniProtKB=P40259 P40259 CD79B PTHR14334:SF2 B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN BETA CHAIN immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;animal organ development#GO:0048513;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;B cell receptor signaling pathway#GO:0050853;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of immune response#GO:0050778;hemopoiesis#GO:0030097;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;B cell activation#GO:0042113;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;immune system development#GO:0002520;regulation of immune response#GO:0050776;multicellular organism development#GO:0007275;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;B cell differentiation#GO:0030183;lymphocyte differentiation#GO:0030098;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 B cell activation#P00010>Ig-beta#P00377 HUMAN|HGNC=17676|UniProtKB=Q9UJ41 Q9UJ41 RABGEF1 PTHR23101:SF25 RAB GDP/GTP EXCHANGE FACTOR RAB5 GDP/GTP EXCHANGE FACTOR guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=13605|UniProtKB=Q8WV35 Q8WV35 LRRC29 PTHR13318:SF169 UNCHARACTERIZED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 29 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=26896|UniProtKB=Q6NW40 Q6NW40 RGMB PTHR31428:SF5 RGM DOMAIN FAMILY MEMBER DRAG-1 RGM DOMAIN FAMILY MEMBER B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=14878|UniProtKB=Q96P09 Q96P09 BIRC8 PTHR10044:SF167 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 8 cysteine-type peptidase activity#GO:0008234;peptidase inhibitor activity#GO:0030414;ubiquitin-protein transferase activity#GO:0004842;protease binding#GO:0002020;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;transferase activity#GO:0016740;cysteine-type endopeptidase activity#GO:0004197;ubiquitin protein ligase activity#GO:0061630;hydrolase activity#GO:0016787;ubiquitin-like protein ligase activity#GO:0061659;cysteine-type endopeptidase inhibitor activity#GO:0004869;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;spindle organization#GO:0007051;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;negative regulation of endopeptidase activity#GO:0010951;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cell-cell signaling by wnt#GO:0198738;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043154;positive regulation of cell communication#GO:0010647;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;mitotic spindle organization#GO:0007052;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of catalytic activity#GO:0050790;positive regulation of Wnt signaling pathway#GO:0030177;mitotic cell cycle process#GO:1903047;protein processing#GO:0016485;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;mitotic spindle assembly#GO:0090307;cell death#GO:0008219;mitotic nuclear division#GO:0140014;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of canonical Wnt signaling pathway#GO:0060828;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;microtubule-based process#GO:0007017;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell cycle#GO:0007049;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 protease inhibitor#PC00191 HUMAN|HGNC=9259|UniProtKB=P30405 P30405 PPIF PTHR11071:SF408 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL chaperone#PC00072 HUMAN|HGNC=25752|UniProtKB=Q96QE3 Q96QE3 ATAD5 PTHR23389:SF21 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 5 pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=14107|UniProtKB=Q969W9 Q969W9 PMEPA1 PTHR16514:SF5 LOW DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING 4A PROTEIN TMEPAI SMAD binding#GO:0046332;protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;regulation of cellular component organization#GO:0051128;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of cellular component organization#GO:0051129;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein-containing complex assembly#GO:0065003;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;response to endogenous stimulus#GO:0009719;regulation of protein-containing complex assembly#GO:0043254;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cellular response to transforming growth factor beta stimulus#GO:1903844;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of transforming growth factor beta receptor signaling pathway#GO:0030512;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=17399|UniProtKB=A7KAX9 A7KAX9 ARHGAP32 PTHR15729:SF13 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 32 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;Golgi apparatus#GO:0005794;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;nucleolus#GO:0005730;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 Gonadotropin-releasing hormone receptor pathway#P06664>RICS#G06882;Gonadotropin-releasing hormone receptor pathway#P06664>RICS#P06765;Gonadotropin-releasing hormone receptor pathway#P06664>RICS#G06669 HUMAN|HGNC=30548|UniProtKB=Q2M238 Q2M238 RRN3P1 PTHR12790:SF0 TRANSCRIPTION INITIATION FACTOR IA RRN3 RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 HUMAN|HGNC=23023|UniProtKB=Q9UPU9 Q9UPU9 SAMD4A PTHR12515:SF8 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED PROTEIN SMAUG HOMOLOG 1 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cellular protein metabolic process#GO:0032269;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=5655|UniProtKB=A0A0C4DH41 A0A0C4DH41 IGHV4-61 PTHR23266:SF323 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=10937|UniProtKB=P41440 P41440 SLC19A1 PTHR10686:SF12 FOLATE TRANSPORTER REDUCED FOLATE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;anion:anion antiporter activity#GO:0015301;antiporter activity#GO:0015297;small molecule binding#GO:0036094;organic acid transmembrane transporter activity#GO:0005342;binding#GO:0005488;amide binding#GO:0033218;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;dicarboxylic acid transmembrane transporter activity#GO:0005310;amide transmembrane transporter activity#GO:0042887;heterocyclic compound binding#GO:1901363;organic acid binding#GO:0043177;anion binding#GO:0043168;ion binding#GO:0043167;active ion transmembrane transporter activity#GO:0022853 vitamin transmembrane transport#GO:0035461;transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=16970|UniProtKB=O43559 O43559 FRS3 PTHR21258:SF39 DOCKING PROTEIN RELATED FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 3 FGF signaling pathway#P00021>FRS2#P00635;Angiogenesis#P00005>FRS-2#P00240 HUMAN|HGNC=3052|UniProtKB=P15924 P15924 DSP PTHR23169:SF26 ENVOPLAKIN DESMOPLAKIN animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;wound healing#GO:0042060;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;skin development#GO:0043588;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;system development#GO:0048731;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;intermediate filament cytoskeleton organization#GO:0045104 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cell-cell contact zone#GO:0044291;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130 HUMAN|HGNC=22231|UniProtKB=Q400G9 Q400G9 AMZ1 PTHR32205:SF4 ARCHAEMETZINCIN-2-RELATED ARCHAEMETZINCIN-1 HUMAN|HGNC=21381|UniProtKB=Q7Z6J8 Q7Z6J8 UBE3D PTHR31531:SF2 E3 UBIQUITIN-PROTEIN LIGASE E3D FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE E3D ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=161|UniProtKB=Q9Y615 Q9Y615 ACTL7A PTHR11937:SF167 ACTIN ACTIN-LIKE PROTEIN 7A actin and actin related protein#PC00039 HUMAN|HGNC=20768|UniProtKB=Q9BQE3 Q9BQE3 TUBA1C PTHR11588:SF298 TUBULIN TUBULIN ALPHA-1C CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Gonadotropin-releasing hormone receptor pathway#P06664>Tubulin#P06772 HUMAN|HGNC=12684|UniProtKB=O15240 O15240 VGF PTHR15159:SF2 NEUROSECRETORY PROTEIN VGF NEUROSECRETORY PROTEIN VGF intercellular signal molecule#PC00207 HUMAN|HGNC=7910|UniProtKB=P06748 P06748 NPM1 PTHR22747:SF28 NUCLEOPLASMIN NUCLEOPHOSMIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;histone binding#GO:0042393 positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;centrosome cycle#GO:0007098;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;transcription, DNA-templated#GO:0006351;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;cytoskeleton organization#GO:0007010;ribosome biogenesis#GO:0042254;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;regulation of centrosome duplication#GO:0010824;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;positive regulation of macromolecule metabolic process#GO:0010604;microtubule organizing center organization#GO:0031023;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;nuclear export#GO:0051168;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;protein transport#GO:0015031;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;intracellular transport#GO:0046907;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;protein-containing complex localization#GO:0031503;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of microtubule-based process#GO:0032886;ribosomal subunit export from nucleus#GO:0000054;macromolecule localization#GO:0033036;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;transport#GO:0006810;cell cycle process#GO:0022402;nucleic acid transport#GO:0050657;microtubule cytoskeleton organization#GO:0000226;centrosome duplication#GO:0051298;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex export from nucleus#GO:0071426;amide transport#GO:0042886;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;organic substance transport#GO:0071702;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of microtubule cytoskeleton organization#GO:0070507;positive regulation of macromolecule biosynthetic process#GO:0010557;protein export from nucleus#GO:0006611;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;microtubule-based process#GO:0007017;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;nucleobase-containing compound transport#GO:0015931;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;RNA export from nucleus#GO:0006405;transcription by RNA polymerase II#GO:0006366;ribosomal small subunit biogenesis#GO:0042274;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;microtubule organizing center#GO:0005815;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 chaperone#PC00072 HUMAN|HGNC=10710|UniProtKB=P0DI82 P0DI82 TRAPPC2B PTHR12403:SF30 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-RELATED localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 HUMAN|HGNC=24323|UniProtKB=Q16568 Q16568 CARTPT PTHR16655:SF0 COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT PROTEIN negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;cell communication#GO:0007154;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cellular response to starvation#GO:0009267;response to stress#GO:0006950;regulation of biological quality#GO:0065008;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;cellular response to extracellular stimulus#GO:0031668 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=20277|UniProtKB=Q96FN9 Q96FN9 DTD2 PTHR10472:SF1 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 2 catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 esterase#PC00097 HUMAN|HGNC=14650|UniProtKB=Q13427 Q13427 PPIG PTHR11071:SF292 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=30803|UniProtKB=Q49AG3 Q49AG3 ZBED5 PTHR45935:SF9 PROTEIN ZBED8-RELATED ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 5 HUMAN|HGNC=29897|UniProtKB=Q8WV22 Q8WV22 NSMCE1 PTHR20973:SF0 NON-SMC ELEMENT 1-RELATED NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25758|UniProtKB=Q8TED0 Q8TED0 UTP15 PTHR19924:SF30 UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;rRNA processing#GO:0006364;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;transcription, DNA-templated#GO:0006351;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;transcription by RNA polymerase I#GO:0006360;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=29379|UniProtKB=A8K855 A8K855 EFCAB7 PTHR46819:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7 calmodulin-related#PC00061 HUMAN|HGNC=26486|UniProtKB=Q6PJW8 Q6PJW8 CNST PTHR28581:SF1 FAMILY NOT NAMED CONSORTIN protein binding#GO:0005515;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of protein transport#GO:0051223;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;protein localization to plasma membrane#GO:0072659;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to membrane#GO:0072657;regulation of protein localization to membrane#GO:1905475;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;peptide transport#GO:0015833;regulation of cellular localization#GO:0060341;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;protein localization to cell periphery#GO:1990778;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=28296|UniProtKB=Q96EX3 Q96EX3 WDR34 PTHR12442:SF26 DYNEIN INTERMEDIATE CHAIN WD REPEAT-CONTAINING PROTEIN 34 dynein heavy chain binding#GO:0045504;protein binding#GO:0005515;binding#GO:0005488 microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;cytoplasmic dynein complex#GO:0005868;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=5978|UniProtKB=Q13261 Q13261 IL15RA PTHR15060:SF0 INTERLEUKIN-15 RECEPTOR SUBUNIT ALPHA INTERLEUKIN-15 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=4177|UniProtKB=P04062 P04062 GBA PTHR11069:SF33 GLUCOSYLCERAMIDASE LYSOSOMAL ACID GLUCOSYLCERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=20137|UniProtKB=Q6ZVK1 Q6ZVK1 TMEM179 PTHR31872:SF4 TRANSMEMBRANE PROTEIN 179 TRANSMEMBRANE PROTEIN 179 HUMAN|HGNC=31984|UniProtKB=B7ZAQ6 B7ZAQ6 GPR89A PTHR15948:SF0 G-PROTEIN COUPLED RECEPTOR 89-RELATED GOLGI PH REGULATOR A-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=6759|UniProtKB=P29966 P29966 MARCKS PTHR14353:SF9 MYRISTOYLATED ALANINE-RICH C-KINASE SUBSTRATE MARCKS MYRISTOYLATED ALANINE-RICH C-KINASE SUBSTRATE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=11788|UniProtKB=P35443 P35443 THBS4 PTHR10199:SF92 THROMBOSPONDIN THROMBOSPONDIN-4 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=8684|UniProtKB=Q9Y5F0 Q9Y5F0 PCDHB13 PTHR24028:SF61 CADHERIN-87A PROTOCADHERIN BETA-13 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=2595|UniProtKB=P04798 P04798 CYP1A1 PTHR24299:SF8 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1A1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=33600|UniProtKB=P0C7N4 P0C7N4 TMEM191B PTHR38498:SF1 TRANSMEMBRANE PROTEIN 191B-RELATED TRANSMEMBRANE PROTEIN 191B-RELATED HUMAN|HGNC=2856|UniProtKB=P52824 P52824 DGKQ PTHR11255:SF34 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE THETA kinase#PC00137 HUMAN|HGNC=6207|UniProtKB=P14923 P14923 JUP PTHR45976:SF3 ARMADILLO SEGMENT POLARITY PROTEIN JUNCTION PLAKOGLOBIN phosphatase binding#GO:0019902;binding#GO:0005488;transcription coactivator activity#GO:0003713;cadherin binding#GO:0045296;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;signaling receptor binding#GO:0005102;DNA-binding transcription factor binding#GO:0140297;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;hormone receptor binding#GO:0051427 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 Alzheimer disease-presenilin pathway#P00004>gammacatenin#P00153 HUMAN|HGNC=5432|UniProtKB=P17181 P17181 IFNAR1 PTHR20859:SF54 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON ALPHA/BETA RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866 HUMAN|HGNC=10779|UniProtKB=Q5T4F7 Q5T4F7 SFRP5 PTHR11309:SF46 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;non-canonical Wnt signaling pathway#GO:0035567;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>sFRP#P01434 HUMAN|HGNC=23596|UniProtKB=Q6L8H4 Q6L8H4 KRTAP5-1 PTHR23262:SF127 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-1 HUMAN|HGNC=30701|UniProtKB=O75949 O75949 FAM155B PTHR15819:SF8 TRANSMEMBRANE PROTEIN FAM155 TRANSMEMBRANE PROTEIN FAM155B calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;divalent metal ion transport#GO:0070838;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=7784|UniProtKB=Q12857 Q12857 NFIA PTHR11492:SF6 NUCLEAR FACTOR I NUCLEAR FACTOR 1 A-TYPE cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=10819|UniProtKB=O43765 O43765 SGTA PTHR45831:SF3 LD24721P SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN ALPHA molecular adaptor activity#GO:0060090;binding#GO:0005488 cellular localization#GO:0051641;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;posttranslational protein targeting to endoplasmic reticulum membrane#GO:0006620;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;establishment of protein localization to endoplasmic reticulum#GO:0072599;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;protein localization to endoplasmic reticulum#GO:0070972;chaperone-mediated protein folding#GO:0061077;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;regulation of cellular process#GO:0050794;protein transport#GO:0015031;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;organonitrogen compound catabolic process#GO:1901565;amide transport#GO:0042886;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;protein localization to membrane#GO:0072657;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;protein targeting to membrane#GO:0006612;response to chemical#GO:0042221;protein folding#GO:0006457;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;ubiquitin-dependent ERAD pathway#GO:0030433;intracellular protein transport#GO:0006886;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=20148|UniProtKB=A6NEE1 A6NEE1 PLEKHD1 PTHR14383:SF1 SWAP-70 RECOMBINASE PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY D MEMBER 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=8352|UniProtKB=Q8NGP8 Q8NGP8 OR5M1 PTHR48018:SF100 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=16725|UniProtKB=Q86X45 Q86X45 LRRC6 PTHR18849:SF15 LEUCINE RICH REPEAT PROTEIN PROTEIN TILB HOMOLOG HUMAN|HGNC=16985|UniProtKB=Q9BTZ2 Q9BTZ2 DHRS4 PTHR43943:SF8 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 4-RELATED dehydrogenase#PC00092 HUMAN|HGNC=29969|UniProtKB=Q8TDB4 Q8TDB4 MGARP PTHR22910:SF6 PROTEIN MGARP PROTEIN MGARP HUMAN|HGNC=2071|UniProtKB=P49761 P49761 CLK3 PTHR45646:SF10 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK3 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=32463|UniProtKB=P0DKX0 P0DKX0 ZNF728 PTHR24377:SF739 IP01015P-RELATED ZINC FINGER PROTEIN 728 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28983|UniProtKB=Q12767 Q12767 TMEM94 PTHR13219:SF6 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 94 HUMAN|HGNC=8910|UniProtKB=P06401 P06401 PGR PTHR48092:SF6 KNIRPS-RELATED PROTEIN-RELATED PROGESTERONE RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Gonadotropin-releasing hormone receptor pathway#P06664>PR#P06708 HUMAN|HGNC=9577|UniProtKB=P78330 P78330 PSPH PTHR43344:SF2 PHOSPHOSERINE PHOSPHATASE PHOSPHOSERINE PHOSPHATASE cation binding#GO:0043169;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;magnesium ion binding#GO:0000287;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;ion binding#GO:0043167;phosphoric ester hydrolase activity#GO:0042578 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phosphatase#PC00181 Serine glycine biosynthesis#P02776>Phosphoserine phosphatase#P03159 HUMAN|HGNC=1117|UniProtKB=Q9UPA5 Q9UPA5 BSN PTHR14113:SF1 PICCOLO/BASSOON PROTEIN BASSOON structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;protein localization to synapse#GO:0035418;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;axon#GO:0030424;presynaptic active zone#GO:0048786;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=3274|UniProtKB=O75821 O75821 EIF3G PTHR10352:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G translation initiation factor#PC00224 HUMAN|HGNC=26654|UniProtKB=Q8N715 Q8N715 CCDC185 PTHR33663:SF3 FAMILY NOT NAMED COILED-COIL DOMAIN-CONTAINING PROTEIN 185 HUMAN|HGNC=21180|UniProtKB=Q5TGI4 Q5TGI4 SAMD5 PTHR12301:SF8 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 5 HUMAN|HGNC=10721|UniProtKB=P16109 P16109 SELP PTHR19325:SF484 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING P-SELECTIN HUMAN|HGNC=4761|UniProtKB=P06899 P06899 H2BC11 PTHR23428:SF326 HISTONE H2B HISTONE H2B TYPE 1-J nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=29499|UniProtKB=Q6P179 Q6P179 ERAP2 PTHR11533:SF239 PROTEASE M1 ZINC METALLOPROTEASE ENDOPLASMIC RETICULUM AMINOPEPTIDASE 2 cation binding#GO:0043169;metallopeptidase activity#GO:0008237;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;peptide binding#GO:0042277;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;peptidase activity#GO:0008233;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=20194|UniProtKB=O15160 O15160 POLR1C PTHR11800:SF13 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=25894|UniProtKB=Q96K75 Q96K75 ZNF514 PTHR24377:SF908 IP01015P-RELATED ZINC FINGER PROTEIN 514 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2904|UniProtKB=Q8TDM6 Q8TDM6 DLG5 PTHR46360:SF1 DISKS LARGE HOMOLOG 5 DISKS LARGE HOMOLOG 5 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29882|UniProtKB=Q9H1K1 Q9H1K1 ISCU PTHR10093:SF26 IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG IRON-SULFUR CLUSTER ASSEMBLY ENZYME ISCU, MITOCHONDRIAL cation binding#GO:0043169;4 iron, 4 sulfur cluster binding#GO:0051539;ferrous iron binding#GO:0008198;metal cluster binding#GO:0051540;iron-sulfur cluster binding#GO:0051536;iron ion binding#GO:0005506;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;transition metal ion homeostasis#GO:0055076;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular iron ion homeostasis#GO:0006879;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;iron ion homeostasis#GO:0055072;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=3200|UniProtKB=Q5VTE0 Q5VTE0 EEF1A1P5 PTHR23115:SF222 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 1-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111 cellular macromolecule biosynthetic process#GO:0034645;sulfur compound metabolic process#GO:0006790;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation factor#PC00223 HUMAN|HGNC=27296|UniProtKB=Q8N0U2 Q8N0U2 TMEM61 PTHR37151:SF1 TRANSMEMBRANE PROTEIN 61 TRANSMEMBRANE PROTEIN 61 HUMAN|HGNC=16507|UniProtKB=Q8TBG9 Q8TBG9 SYNPR PTHR10306:SF16 SYNAPTOPHYSIN SYNAPTOPORIN syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;syntaxin-1 binding#GO:0017075 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=24765|UniProtKB=Q6PCB5 Q6PCB5 RSBN1L PTHR13354:SF9 ROUND SPERMATID BASIC PROTEIN 1 LYSINE-SPECIFIC DEMETHYLASE RSBN1L membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=16281|UniProtKB=Q96F44 Q96F44 TRIM11 PTHR24103:SF648 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM11 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=25522|UniProtKB=Q9BUR4 Q9BUR4 WRAP53 PTHR13211:SF0 UNCHARACTERIZED TELOMERASE CAJAL BODY PROTEIN 1 HUMAN|HGNC=850|UniProtKB=P48047 P48047 ATP5PO PTHR11910:SF21 ATP SYNTHASE DELTA CHAIN ATP SYNTHASE SUBUNIT O, MITOCHONDRIAL cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular localization#GO:0051641;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;mitochondrial transmembrane transport#GO:1990542;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;intracellular transport#GO:0046907;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial transport#GO:0006839;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;establishment of localization in cell#GO:0051649;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 HUMAN|HGNC=9555|UniProtKB=O75832 O75832 PSMD10 PTHR24126:SF24 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10 HUMAN|HGNC=26752|UniProtKB=Q8N9B4 Q8N9B4 ANKRD42 PTHR24201:SF2 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 42 HUMAN|HGNC=31401|UniProtKB=Q4G0N8 Q4G0N8 SLC9C1 PTHR10110:SF87 SODIUM/HYDROGEN EXCHANGER SODIUM/HYDROGEN EXCHANGER 10 secondary carrier transporter#PC00258 HUMAN|HGNC=23712|UniProtKB=Q8NBB4 Q8NBB4 ZSCAN1 PTHR23226:SF332 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3424|UniProtKB=O75616 O75616 ERAL1 PTHR42698:SF3 GTPASE ERA GTPASE ERA, MITOCHONDRIAL nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;rRNA binding#GO:0019843 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;ribonucleoprotein complex subunit organization#GO:0071826;ribonucleoprotein complex assembly#GO:0022618;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;protein-containing complex subunit organization#GO:0043933 RNA metabolism protein#PC00031 HUMAN|HGNC=12853|UniProtKB=Q04917 Q04917 YWHAH PTHR18860:SF16 14-3-3 PROTEIN 14-3-3 PROTEIN ETA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 HUMAN|HGNC=5234|UniProtKB=P34931 P34931 HSPA1L PTHR19375:SF210 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 1-LIKE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524;ATPase activity#GO:0016887 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;chaperone-mediated protein folding#GO:0061077;cellular response to organic substance#GO:0071310;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;'de novo' protein folding#GO:0006458;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;COP9 signalosome#GO:0008180;vesicle#GO:0031982;intracellular organelle#GO:0043229 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 HUMAN|HGNC=6873|UniProtKB=Q15759 Q15759 MAPK11 PTHR24055:SF109 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 11 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 p38 MAPK pathway#P05918>p38beta#P06029;Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;TGF-beta signaling pathway#P00052>P38#P01275;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>p38#P00562;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Ras Pathway#P04393>p38#P04558;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;B cell activation#P00010>p38#P00384;Oxidative stress response#P00046>p38#P01135;FGF signaling pathway#P00021>p38#P00644 HUMAN|HGNC=1440|UniProtKB=P30988 P30988 CALCR PTHR45620:SF8 PDF RECEPTOR-LIKE PROTEIN-RELATED CALCITONIN RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=12871|UniProtKB=Q9UKY1 Q9UKY1 ZHX1 PTHR15467:SF4 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=26021|UniProtKB=Q9NX58 Q9NX58 LYAR PTHR13100:SF10 CELL GROWTH-REGULATING NUCLEOLAR PROTEIN LYAR CELL GROWTH-REGULATING NUCLEOLAR PROTEIN heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;rRNA processing#GO:0006364;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;transcription, DNA-templated#GO:0006351;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=5960|UniProtKB=O14920 O14920 IKBKB PTHR22969:SF7 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT BETA DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;double-stranded DNA binding#GO:0003690;kinase activity#GO:0016301;protein kinase activity#GO:0004672;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;protein serine/threonine kinase activity#GO:0004674;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;catalytic activity, acting on a protein#GO:0140096 positive regulation of gene expression#GO:0010628;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;tumor necrosis factor-mediated signaling pathway#GO:0033209;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;response to tumor necrosis factor#GO:0034612;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>IKK#P00313;Toll receptor signaling pathway#P00054>IKKbeta#P01360;PDGF signaling pathway#P00047>Ikk#P01146;B cell activation#P00010>IKK#P00397;T cell activation#P00053>IKK#P01330;Interleukin signaling pathway#P00036>Ikk#P00968;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871 HUMAN|HGNC=2472|UniProtKB=P50461 P50461 CSRP3 PTHR24215:SF1 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;structural molecule activity#GO:0005198;binding#GO:0005488 blood circulation#GO:0008015;cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cardiac muscle contraction#GO:0060048;heart contraction#GO:0060047;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;circulatory system process#GO:0003013;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;striated muscle contraction#GO:0006941;cellular component morphogenesis#GO:0032989;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=89|UniProtKB=P11310 P11310 ACADM PTHR48083:SF2 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL dehydrogenase#PC00092 HUMAN|HGNC=6833|UniProtKB=P21397 P21397 MAOA PTHR43563:SF11 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] A oxidase#PC00175 Dopamine receptor mediated signaling pathway#P05912>MAO#P05963;Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067;5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 HUMAN|HGNC=24056|UniProtKB=Q8NHP1 Q8NHP1 AKR7L PTHR43625:SF11 AFLATOXIN B1 ALDEHYDE REDUCTASE AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 3-RELATED reductase#PC00198 HUMAN|HGNC=23724|UniProtKB=Q14CB8 Q14CB8 ARHGAP19 PTHR14963:SF7 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 19 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;small GTPase mediated signal transduction#GO:0007264;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 HUMAN|HGNC=9936|UniProtKB=P04000 P04000 OPN1LW PTHR24240:SF180 OPSIN LONG-WAVE-SENSITIVE OPSIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to abiotic stimulus#GO:0071214;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=16873|UniProtKB=Q92562 Q92562 FIG4 PTHR45738:SF5 POLYPHOSPHOINOSITIDE PHOSPHATASE POLYPHOSPHOINOSITIDE PHOSPHATASE phosphatase#PC00181 HUMAN|HGNC=29818|UniProtKB=Q9H3H9 Q9H3H9 TCEAL2 PTHR14754:SF36 TRANSCRIPTION ELONGATION FACTOR A TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 2 general transcription factor#PC00259 HUMAN|HGNC=20313|UniProtKB=Q86WI1 Q86WI1 PKHD1L1 PTHR46769:SF4 POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1 FIBROCYSTIN-L HUMAN|HGNC=14036|UniProtKB=Q8TCC3 Q8TCC3 MRPL30 PTHR15892:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L30 39S RIBOSOMAL PROTEIN L30, MITOCHONDRIAL ribosomal protein#PC00202 HUMAN|HGNC=24427|UniProtKB=Q6P093 Q6P093 AADACL2 PTHR23024:SF223 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE-LIKE 2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 deacetylase#PC00087 HUMAN|HGNC=20354|UniProtKB=Q53FD0 Q53FD0 ZC2HC1C PTHR14649:SF1 ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C HUMAN|HGNC=25168|UniProtKB=Q96DY2 Q96DY2 IQCD PTHR31598:SF1 IQ DOMAIN-CONTAINING PROTEIN D DYNEIN REGULATORY COMPLEX PROTEIN 10 HUMAN|HGNC=24185|UniProtKB=P46736 P46736 BRCC3 PTHR10410:SF34 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED LYS-63-SPECIFIC DEUBIQUITINASE BRCC36 thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;metallopeptidase activity#GO:0008237;omega peptidase activity#GO:0008242;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein K63-linked deubiquitination#GO:0070536;protein modification process#GO:0036211;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;histone deubiquitination#GO:0016578;proteolysis#GO:0006508;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;histone modification#GO:0016570;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;covalent chromatin modification#GO:0016569;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;chromatin organization#GO:0006325;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 translation initiation factor#PC00224 HUMAN|HGNC=24468|UniProtKB=Q8IUH3 Q8IUH3 RBM45 PTHR24012:SF812 RNA BINDING PROTEIN RNA-BINDING PROTEIN 45 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=19349|UniProtKB=Q7Z4S6 Q7Z4S6 KIF21A PTHR24115:SF398 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF21A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=31041|UniProtKB=Q2MJR0 Q2MJR0 SPRED3 PTHR11202:SF19 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of response to DNA damage stimulus#GO:2001020;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;cellular response to DNA damage stimulus#GO:0006974;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of response to DNA damage stimulus#GO:2001022;signal transduction by p53 class mediator#GO:0072331;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;signal transduction in response to DNA damage#GO:0042770;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of MAP kinase activity#GO:0043407;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;protein deacylation#GO:0035601;negative regulation of cellular protein metabolic process#GO:0032269;peptidyl-threonine phosphorylation#GO:0018107;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 scaffold/adaptor protein#PC00226 HUMAN|HGNC=23034|UniProtKB=Q6P9H4 Q6P9H4 CNKSR3 PTHR12844:SF17 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 3 HUMAN|HGNC=31805|UniProtKB=Q5JRK9 Q5JRK9 PAGE2B PTHR14047:SF34 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN FAMILY E MEMBER 3-RELATED HUMAN|HGNC=26520|UniProtKB=Q8N6L0 Q8N6L0 KASH5 PTHR47300:SF1 PROTEIN KASH5 PROTEIN KASH5 protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;telophase#GO:0051326;chromosome segregation#GO:0007059;M phase#GO:0000279;chromosome organization involved in meiotic cell cycle#GO:0070192;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;meiosis I cell cycle process#GO:0061982;actin filament organization#GO:0007015;reproductive process#GO:0022414;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cell cycle phase#GO:0022403;establishment of organelle localization#GO:0051656;meiosis I#GO:0007127;spindle localization#GO:0051653;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;meiosis I cell cycle phase#GO:0098764;establishment of chromosome localization#GO:0051303;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;actin cytoskeleton organization#GO:0030036;chromosome localization#GO:0050000 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;condensed chromosome#GO:0000793;vacuole#GO:0005773;organelle membrane#GO:0031090;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;nuclear membrane#GO:0031965;non-membrane-bounded organelle#GO:0043228;intrinsic component of membrane#GO:0031224;organelle outer membrane#GO:0031968;chromosome#GO:0005694;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;spindle#GO:0005819;envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;spindle pole#GO:0000922;membrane protein complex#GO:0098796;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle lumen#GO:0070013;cell periphery#GO:0071944;membrane#GO:0016020;whole membrane#GO:0098805;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;chromosome, telomeric region#GO:0000781;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;outer membrane#GO:0019867;synaptonemal complex#GO:0000795;plasma membrane#GO:0005886 HUMAN|HGNC=9186|UniProtKB=O75417 O75417 POLQ PTHR10133:SF58 DNA POLYMERASE I DNA POLYMERASE THETA hydrolase activity, acting on ester bonds#GO:0016788;DNA-directed DNA polymerase activity#GO:0003887;nuclease activity#GO:0004518;transferase activity#GO:0016740;5'-3' exonuclease activity#GO:0008409;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;DNA polymerase activity#GO:0034061 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;DNA biosynthetic process#GO:0071897;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 DNA-directed DNA polymerase#PC00018 HUMAN|HGNC=2584|UniProtKB=Q9NQC7 Q9NQC7 CYLD PTHR11830:SF15 40S RIBOSOMAL PROTEIN S3A UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD thiol-dependent ubiquitin-specific protease activity#GO:0004843;hydrolase activity#GO:0016787;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;nuclear division#GO:0000280;protein K63-linked deubiquitination#GO:0070536;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;protein modification process#GO:0036211;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of programmed cell death#GO:0043068;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;cell death#GO:0008219;mitotic nuclear division#GO:0140014;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;nucleic acid-templated transcription#GO:0097659;positive regulation of apoptotic process#GO:0043065;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;regulation of DNA-binding transcription factor activity#GO:0051090;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of cell death#GO:0010942;regulation of mitotic cell cycle#GO:0007346;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of DNA-binding transcription factor activity#GO:0043433;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ribosomal protein#PC00202 HUMAN|HGNC=3401|UniProtKB=P07099 P07099 EPHX1 PTHR21661:SF35 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE 1 hydrolase#PC00121 HUMAN|HGNC=9529|UniProtKB=P11801 P11801 PSKH1 PTHR24347:SF254 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE H1 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=1094|UniProtKB=Q86WA6 Q86WA6 BPHL PTHR46331:SF2 VALACYCLOVIR HYDROLASE VALACYCLOVIR HYDROLASE hydrolase#PC00121 HUMAN|Gene=YJ016_HUMAN|UniProtKB=Q499Y3 Q499Y3 - PTHR14787:SF2 C10ORF188 FAMILY MEMBER SUBFAMILY NOT NAMED HUMAN|HGNC=7945|UniProtKB=P17342 P17342 NPR3 PTHR44755:SF1 NATRIURETIC PEPTIDE RECEPTOR 3-RELATED ATRIAL NATRIURETIC PEPTIDE RECEPTOR 3 transmembrane signal receptor#PC00197 HUMAN|HGNC=14845|UniProtKB=Q8NGN5 Q8NGN5 OR10G8 PTHR26453:SF682 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G8 transmembrane signal receptor#PC00197 HUMAN|HGNC=23666|UniProtKB=Q5CZ79 Q5CZ79 ANKRD20A8P PTHR24147:SF1 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 20A1-RELATED HUMAN|HGNC=4378|UniProtKB=P49915 P49915 GMPS PTHR11922:SF2 GMP SYNTHASE-RELATED GMP SYNTHASE [GLUTAMINE-HYDROLYZING] ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 De novo purine biosynthesis#P02738>GMP synthase#P02899 HUMAN|HGNC=20665|UniProtKB=Q9NY72 Q9NY72 SCN3B PTHR10546:SF1 SODIUM CHANNEL SUBUNIT BETA-1 AND 3 SODIUM CHANNEL SUBUNIT BETA-3 blood circulation#GO:0008015;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;heart contraction#GO:0060047;regulation of membrane potential#GO:0042391;cardiac muscle contraction#GO:0060048;system process#GO:0003008;action potential#GO:0001508;regulation of system process#GO:0044057;cellular process#GO:0009987;circulatory system process#GO:0003013;actin-mediated cell contraction#GO:0070252;striated muscle contraction#GO:0006941;regulation of biological process#GO:0050789;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;signaling#GO:0023052;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 voltage-gated ion channel#PC00241 HUMAN|HGNC=4285|UniProtKB=O75712 O75712 GJB3 PTHR11984:SF65 CONNEXIN GAP JUNCTION BETA-3 PROTEIN gap junction#PC00105 HUMAN|HGNC=13813|UniProtKB=Q9BWU0 Q9BWU0 SLC4A1AP PTHR23308:SF62 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 KANADAPTIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA splicing factor#PC00148 HUMAN|HGNC=15910|UniProtKB=Q9Y697 Q9Y697 NFS1 PTHR11601:SF34 CYSTEINE DESULFURYLASE FAMILY MEMBER CYSTEINE DESULFURASE, MITOCHONDRIAL-RELATED lyase#PC00144 HUMAN|HGNC=2098|UniProtKB=Q9Y471 Q9Y471 CMAHP PTHR46522:SF3 CYTIDINE MONOPHOSPHATE-N-ACETYLNEURAMINIC ACID HYDROXYLASE INACTIVE CYTIDINE MONOPHOSPHATE-N-ACETYLNEURAMINIC ACID HYDROXYLASE hydroxylase#PC00122 HUMAN|HGNC=19155|UniProtKB=P57773 P57773 GJA9 PTHR11984:SF60 CONNEXIN GAP JUNCTION ALPHA-9 PROTEIN gap junction#PC00105 HUMAN|HGNC=954|UniProtKB=Q9NY43 Q9NY43 BARHL2 PTHR24330:SF4 HOMEOBOX PROTEIN BARH-LIKE BARH-LIKE 2 HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=2190|UniProtKB=Q5TAT6 Q5TAT6 COL13A1 PTHR24023:SF871 COLLAGEN ALPHA COLLAGEN ALPHA-1(XIII) CHAIN carbohydrate derivative binding#GO:0097367;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;heparin binding#GO:0008201;ion binding#GO:0043167;anion binding#GO:0043168;glycosaminoglycan binding#GO:0005539 cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;cell-matrix adhesion#GO:0007160;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;biological adhesion#GO:0022610;developmental process#GO:0032502;cell-cell adhesion#GO:0098609;multicellular organismal process#GO:0032501;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;extracellular matrix organization#GO:0030198;morphogenesis of a branching structure#GO:0001763 cell junction#GO:0030054;extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=21641|UniProtKB=O95859 O95859 TSPAN12 PTHR19282:SF462 TETRASPANIN TETRASPANIN-12 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=12123|UniProtKB=A0A087WT03 A0A087WT03 TRAV26-1 PTHR19433:SF111 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 26-1 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=2473|UniProtKB=P01037 P01037 CST1 PTHR46186:SF5 CYSTATIN CYSTATIN-SN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=41915|UniProtKB=A6NGZ8 A6NGZ8 SMIM9 PTHR41687:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 9 SMALL INTEGRAL MEMBRANE PROTEIN 9 HUMAN|HGNC=5604|UniProtKB=A0A0B4J1X8 A0A0B4J1X8 IGHV3-43 PTHR23266:SF236 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-43-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=23177|UniProtKB=Q14145 Q14145 KEAP1 PTHR24412:SF162 KELCH PROTEIN KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=2355|UniProtKB=P06850 P06850 CRH PTHR15035:SF9 CORTICOLIBERIN/UROCORTIN CORTICOLIBERIN peptide hormone#PC00179 Cortocotropin releasing factor receptor signaling pathway#P04380>CRF#P04454;Cortocotropin releasing factor receptor signaling pathway#P04380>ProCRF (Pro Corticotropin-Releasing Factor)#P04456 HUMAN|HGNC=16090|UniProtKB=O00264 O00264 PGRMC1 PTHR10281:SF23 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=29659|UniProtKB=Q0VG99 Q0VG99 MESP2 PTHR20937:SF17 IP14615P MESODERM POSTERIOR PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;ectoderm formation#GO:0001705;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;mesoderm morphogenesis#GO:0048332;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;ectoderm development#GO:0007398;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;epithelium development#GO:0060429;mesoderm formation#GO:0001707;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;endoderm formation#GO:0001706;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;mesoderm development#GO:0007498;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11801|UniProtKB=P04216 P04216 THY1 PTHR19226:SF2 THY-1 MEMBRANE GLYCOPROTEIN THY-1 MEMBRANE GLYCOPROTEIN cell adhesion molecule#PC00069 HUMAN|HGNC=4141|UniProtKB=P04406 P04406 GAPDH PTHR10836:SF111 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;purine ribonucleoside diphosphate metabolic process#GO:0009179;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676;Huntington disease#P00029>GAPDH#P00810 HUMAN|HGNC=9104|UniProtKB=O15031 O15031 PLXNB2 PTHR22625:SF9 PLEXIN PLEXIN-B2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of GTPase activity#GO:0043087;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of neuron differentiation#GO:0045664;negative regulation of cell adhesion#GO:0007162;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;positive regulation of neuron projection development#GO:0010976;locomotion#GO:0040011;taxis#GO:0042330;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of cell projection organization#GO:0031346;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;biological adhesion#GO:0022610;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of cell adhesion#GO:0030155;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;positive regulation of neuron differentiation#GO:0045666;cellular response to stimulus#GO:0051716;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;cell migration#GO:0016477 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=24596|UniProtKB=Q96FJ2 Q96FJ2 DYNLL2 PTHR11886:SF100 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 2, CYTOPLASMIC protein binding#GO:0005515;binding#GO:0005488 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;microtubule cytoskeleton organization#GO:0000226;regulation of catalytic activity#GO:0050790;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;positive regulation of catalytic activity#GO:0043085;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=26135|UniProtKB=Q9H707 Q9H707 ZNF552 PTHR24377:SF702 IP01015P-RELATED ZINC FINGER PROTEIN 552 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=20973|UniProtKB=O94910 O94910 ADGRL1 PTHR12011:SF62 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR L1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 presynapse#GO:0098793;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;axon#GO:0030424;asymmetric synapse#GO:0032279;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=29248|UniProtKB=Q86T90 Q86T90 KIAA1328 PTHR28375:SF1 FAMILY NOT NAMED PROTEIN HINDERIN HUMAN|HGNC=11132|UniProtKB=P60880 P60880 SNAP25 PTHR19305:SF5 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 25 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;syntaxin-1 binding#GO:0017075;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;regulated exocytosis#GO:0045055;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular#GO:0005622;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 SNARE protein#PC00034 Synaptic vesicle trafficking#P05734>SNAP-25#P05778;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 HUMAN|HGNC=11730|UniProtKB=O14746 O14746 TERT PTHR12066:SF0 TELOMERASE REVERSE TRANSCRIPTASE TELOMERASE REVERSE TRANSCRIPTASE nucleic acid binding#GO:0003676;RNA-directed DNA polymerase activity#GO:0003964;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;telomerase activity#GO:0003720;telomerase RNA binding#GO:0070034;sequence-specific DNA binding#GO:0043565;RNA binding#GO:0003723;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 cellular aromatic compound metabolic process#GO:0006725;telomere maintenance via telomere lengthening#GO:0010833;cellular component biogenesis#GO:0044085;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;telomere-telomerase complex assembly#GO:1905324;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;telomere maintenance via telomerase#GO:0007004;anatomical structure homeostasis#GO:0060249;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;RNA-dependent DNA biosynthetic process#GO:0006278;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA metabolic process#GO:0006259 DNA polymerase complex#GO:0042575;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;telomerase holoenzyme complex#GO:0005697;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA metabolism protein#PC00009 HUMAN|HGNC=9526|UniProtKB=Q00887 Q00887 PSG9 PTHR44427:SF14 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 9 HUMAN|HGNC=8980|UniProtKB=O00459 O00459 PIK3R2 PTHR10155:SF1 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;regulation of catalytic activity#GO:0050790;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;regulation of molecular function#GO:0065009;cellular response to insulin stimulus#GO:0032869;phosphorylation#GO:0016310;signaling#GO:0023052;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;regulation of lipid metabolic process#GO:0019216;cellular lipid metabolic process#GO:0044255;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;phosphatidylinositol phosphorylation#GO:0046854;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 PDGF signaling pathway#P00047>PI3K#P01168;PI3 kinase pathway#P00048>p85#P01202;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;VEGF signaling pathway#P00056>PI3K#P01413;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 HUMAN|HGNC=21738|UniProtKB=Q3MIX3 Q3MIX3 ADCK5 PTHR43173:SF28 ABC1 FAMILY PROTEIN ABC1 DOMAIN-CONTAINING PROTEIN ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=30760|UniProtKB=Q9HC07 Q9HC07 TMEM165 PTHR12608:SF1 TRANSMEMBRANE PROTEIN HTP-1 RELATED TRANSMEMBRANE PROTEIN 165 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 HUMAN|HGNC=28997|UniProtKB=Q93073 Q93073 SECISBP2L PTHR13284:SF10 GH01354P SELENOCYSTEINE INSERTION SEQUENCE-BINDING PROTEIN 2-LIKE nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;mRNA 3'-UTR binding#GO:0003730 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 HUMAN|HGNC=9965|UniProtKB=Q9P2R6 Q9P2R6 RERE PTHR13859:SF12 ATROPHIN-RELATED ARGININE-GLUTAMIC ACID DIPEPTIDE REPEATS PROTEIN transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription corepressor activity#GO:0003714;RNA polymerase II transcription factor binding#GO:0001085;protein binding#GO:0005515;molecular function regulator#GO:0098772;transcription factor binding#GO:0008134 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=15959|UniProtKB=Q9H112 Q9H112 CST11 PTHR47886:SF1 CYSTATIN-11 CYSTATIN-11 defense response to bacterium#GO:0042742;defense response to Gram-negative bacterium#GO:0050829;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response#GO:0006952 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;C2 axonemal microtubule#GO:1990720;B axonemal microtubule#GO:0097650;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;C1 axonemal microtubule#GO:1990719;nucleus#GO:0005634;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;axonemal microtubule#GO:0005879 HUMAN|HGNC=15312|UniProtKB=Q8NGG0 Q8NGG0 OR8J3 PTHR48018:SF41 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8J3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=1258|UniProtKB=Q9NVD3 Q9NVD3 SETD4 PTHR13271:SF11 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE SET DOMAIN-CONTAINING PROTEIN 4 N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein alkylation#GO:0008213;protein methylation#GO:0006479;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 methyltransferase#PC00155 HUMAN|HGNC=10599|UniProtKB=P37088 P37088 SCNN1A PTHR11690:SF124 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT ALPHA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=20598|UniProtKB=Q86WA8 Q86WA8 LONP2 PTHR10046:SF24 ATP DEPENDENT LON PROTEASE FAMILY MEMBER LON PROTEASE HOMOLOG 2, PEROXISOMAL serine protease#PC00203 HUMAN|HGNC=8065|UniProtKB=Q9UKX7 Q9UKX7 NUP50 PTHR23138:SF141 RAN BINDING PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP50 scaffold/adaptor protein#PC00226 HUMAN|HGNC=7728|UniProtKB=Q96PU5 Q96PU5 NEDD4L PTHR11254:SF310 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE inorganic molecular entity transmembrane transporter activity#GO:0015318;cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 regulation of dendrite development#GO:0050773;regulation of sodium ion transport#GO:0002028;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;regulation of metal ion transport#GO:0010959;dendrite development#GO:0016358;inorganic cation transmembrane transport#GO:0098662;protein catabolic process#GO:0030163;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;inorganic ion transmembrane transport#GO:0098660;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of ion transmembrane transporter activity#GO:0032412;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of transmembrane transporter activity#GO:0022898;proteasomal protein catabolic process#GO:0010498;regulation of transporter activity#GO:0032409;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of transmembrane transport#GO:0034762;regulation of multicellular organismal process#GO:0051239;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;negative regulation of transport#GO:0051051;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of macromolecule metabolic process#GO:0010604;regulation of neuron differentiation#GO:0045664;ion transmembrane transport#GO:0034220;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;positive regulation of catabolic process#GO:0009896;neuron development#GO:0048666;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;regulation of ion transport#GO:0043269;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of dendrite morphogenesis#GO:0048814;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;transport#GO:0006810;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of protein catabolic process#GO:0042176;cation transport#GO:0006812;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cation transmembrane transport#GO:0098655;cell differentiation#GO:0030154;system development#GO:0048731;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;catabolic process#GO:0009056;plasma membrane bounded cell projection morphogenesis#GO:0120039;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;metal ion transport#GO:0030001;monovalent inorganic cation transport#GO:0015672;cell morphogenesis involved in differentiation#GO:0000904;regulation of cation transmembrane transport#GO:1904062;regulation of cell development#GO:0060284;transmembrane transport#GO:0055085;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;multicellular organism development#GO:0007275;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cell morphogenesis#GO:0000902;cellular process#GO:0009987;dendrite morphogenesis#GO:0048813;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;positive regulation of protein metabolic process#GO:0051247;sodium ion transport#GO:0006814;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;generation of neurons#GO:0048699;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;sodium ion transmembrane transport#GO:0035725;negative regulation of molecular function#GO:0044092 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=14847|UniProtKB=Q9H341 Q9H341 OR51M1 PTHR26450:SF44 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51M1 transmembrane signal receptor#PC00197 HUMAN|HGNC=16633|UniProtKB=Q9Y3D5 Q9Y3D5 MRPS18C PTHR13479:SF57 30S RIBOSOMAL PROTEIN S18 28S RIBOSOMAL PROTEIN S18C, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 HUMAN|HGNC=10962|UniProtKB=O94956 O94956 SLCO2B1 PTHR11388:SF87 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2B1 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=11742|UniProtKB=P05549 P05549 TFAP2A PTHR10812:SF8 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 general transcription factor#PC00259 HUMAN|HGNC=30871|UniProtKB=Q9UBM8 Q9UBM8 MGAT4C PTHR12062:SF14 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE C transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=14295|UniProtKB=Q9UPX8 Q9UPX8 SHANK2 PTHR24135:SF17 SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 2 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular component biogenesis#GO:0044085;regulation of dendrite development#GO:0050773;positive regulation of signal transduction#GO:0009967;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of transmembrane transporter activity#GO:0022898;central nervous system development#GO:0007417;positive regulation of cell development#GO:0010720;regulation of transporter activity#GO:0032409;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;regulation of multicellular organismal process#GO:0051239;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of synaptic plasticity#GO:0048167;cellular component organization or biogenesis#GO:0071840;regulation of ion transmembrane transport#GO:0034765;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;head development#GO:0060322;signal transduction#GO:0007165;neurogenesis#GO:0022008;regulation of signaling#GO:0023051;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of system process#GO:0044057;cation transport#GO:0006812;ionotropic glutamate receptor signaling pathway#GO:0035235;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;system development#GO:0048731;neuron differentiation#GO:0030182;cell junction assembly#GO:0034329;signaling#GO:0023052;cell-cell signaling#GO:0007267;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;cell morphogenesis#GO:0000902;nervous system process#GO:0050877;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of signaling receptor activity#GO:0010469;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;synapse assembly#GO:0007416;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;positive regulation of cellular component organization#GO:0051130;positive regulation of synaptic transmission#GO:0050806;synaptic transmission, glutamatergic#GO:0035249;cell projection organization#GO:0030030;dendrite development#GO:0016358;system process#GO:0003008;brain development#GO:0007420;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;dendritic spine organization#GO:0097061;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;regulation of dendritic spine development#GO:0060998;trans-synaptic signaling#GO:0099537;ion transmembrane transport#GO:0034220;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;neuromuscular junction development#GO:0007528;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;synapse organization#GO:0050808;neuron projection development#GO:0031175;modulation of chemical synaptic transmission#GO:0050804;regulation of cell projection organization#GO:0031344;neuron projection morphogenesis#GO:0048812;regulation of ion transport#GO:0043269;regulation of trans-synaptic signaling#GO:0099177;neuron development#GO:0048666;positive regulation of multicellular organismal process#GO:0051240;positive regulation of cell projection organization#GO:0031346;regulation of neurotransmitter receptor activity#GO:0099601;chemical synaptic transmission, postsynaptic#GO:0099565;animal organ development#GO:0048513;transport#GO:0006810;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;cation transmembrane transport#GO:0098655;positive regulation of response to stimulus#GO:0048584;regulation of transport#GO:0051049;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;positive regulation of neuron differentiation#GO:0045666;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;developmental growth#GO:0048589;regulation of cation transmembrane transport#GO:1904062;positive regulation of cell differentiation#GO:0045597;ion transport#GO:0006811;multicellular organism development#GO:0007275;regulation of AMPA receptor activity#GO:2000311;positive regulation of developmental process#GO:0051094;dendrite morphogenesis#GO:0048813;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;organelle assembly#GO:0070925;response to stimulus#GO:0050896;organelle organization#GO:0006996;cell junction organization#GO:0034330;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;generation of neurons#GO:0048699 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;cell junction#GO:0030054;ion channel complex#GO:0034702;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 Ionotropic glutamate receptor pathway#P00037>PSD95#P00999 HUMAN|HGNC=26979|UniProtKB=Q6P3W2 Q6P3W2 DNAJC24 PTHR45255:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 24 DNAJ HOMOLOG SUBFAMILY C MEMBER 24 ferrous iron binding#GO:0008198;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;cation binding#GO:0043169;iron ion binding#GO:0005506;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;ATPase activator activity#GO:0001671;ATPase activity#GO:0016887 biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of hydrolase activity#GO:0051345 chaperone#PC00072 HUMAN|HGNC=17043|UniProtKB=Q7RTP0 Q7RTP0 NIPA1 PTHR12570:SF17 UNCHARACTERIZED MAGNESIUM TRANSPORTER NIPA1 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=17514|UniProtKB=Q9NSC5 Q9NSC5 HOMER3 PTHR10918:SF4 HOMER HOMER PROTEIN HOMOLOG 3 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;metal ion transport#GO:0030001;regulation of metal ion transport#GO:0010959;ion transport#GO:0006811;transport#GO:0006810;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;cell communication#GO:0007154;cation transport#GO:0006812;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;calcium ion transport#GO:0006816;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;divalent inorganic cation transport#GO:0072511;G protein-coupled receptor signaling pathway#GO:0007186;regulation of ion transport#GO:0043269;signaling#GO:0023052 synapse#GO:0045202;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;postsynaptic density#GO:0014069;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;asymmetric synapse#GO:0032279;cytoplasm#GO:0005737;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=13595|UniProtKB=O75426 O75426 FBXO24 PTHR47004:SF1 F-BOX ONLY PROTEIN 24 F-BOX ONLY PROTEIN 24 HUMAN|HGNC=5226|UniProtKB=O75031 O75031 HSF2BP PTHR15434:SF2 HEAT SHOCK FACTOR 2-BINDING PROTEIN HEAT SHOCK FACTOR 2-BINDING PROTEIN cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=6259|UniProtKB=O60928 O60928 KCNJ13 PTHR11767:SF3 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 13 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=1750|UniProtKB=P55287 P55287 CDH11 PTHR24027:SF85 CADHERIN-23 CADHERIN-11 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=30327|UniProtKB=O95059 O95059 RPP14 PTHR43437:SF3 HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED dehydratase#PC00091 HUMAN|HGNC=3711|UniProtKB=P62942 P62942 FKBP1A PTHR10516:SF301 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A-RELATED chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 HUMAN|HGNC=11863|UniProtKB=O76062 O76062 TM7SF2 PTHR21257:SF54 DELTA(14)-STEROL REDUCTASE DELTA(14)-STEROL REDUCTASE TM7SF2 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;steroid metabolic process#GO:0008202;lipid metabolic process#GO:0006629;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 reductase#PC00198 HUMAN|HGNC=30695|UniProtKB=Q8NI37 Q8NI37 PPTC7 PTHR12320:SF1 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE PTC7 HOMOLOG protein phosphatase#PC00195 HUMAN|HGNC=17930|UniProtKB=Q9UJV8 Q9UJV8 PURG PTHR12611:SF3 PUR-TRANSCRIPTIONAL ACTIVATOR PURINE-RICH ELEMENT-BINDING PROTEIN GAMMA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=24932|UniProtKB=Q9NZ63 Q9NZ63 C9orf78 PTHR13486:SF2 TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER TELOMERE LENGTH AND SILENCING PROTEIN 1 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=25406|UniProtKB=Q8N3J9 Q8N3J9 ZNF664 PTHR24384:SF30 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 664 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=32213|UniProtKB=Q5T7M9 Q5T7M9 DIPK1A PTHR21093:SF4 UNCHARACTERIZED DIVERGENT PROTEIN KINASE DOMAIN 1A HUMAN|HGNC=6394|UniProtKB=P52294 P52294 KPNA1 PTHR23316:SF3 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA-5 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;synaptic signaling#GO:0099536;protein localization to organelle#GO:0033365;protein import#GO:0017038;cell-cell signaling#GO:0007267;signaling#GO:0023052;nuclear transport#GO:0051169;cellular response to stimulus#GO:0051716;establishment of protein localization to organelle#GO:0072594;cell communication#GO:0007154;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=9056|UniProtKB=Q01970 Q01970 PLCB3 PTHR10336:SF11 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-3 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;phospholipase C activity#GO:0004629;calmodulin binding#GO:0005516;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;2-arachidonoylglycerol biosynthesis#P05726>PLC#P05738;Endogenous cannabinoid signaling#P05730>PLC#P05746;Endothelin signaling pathway#P00019>PLCbeta#P00591;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>PLC#P05933;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484 HUMAN|HGNC=21149|UniProtKB=P79522 P79522 PRR3 PTHR47398:SF1 PROLINE-RICH PROTEIN 3 PROLINE-RICH PROTEIN 3 HUMAN|HGNC=19234|UniProtKB=Q6P4F1 Q6P4F1 FUT10 PTHR11929:SF131 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE 10 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111 HUMAN|HGNC=18399|UniProtKB=Q8N5I4 Q8N5I4 DHRSX PTHR24320:SF148 RETINOL DEHYDROGENASE DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER ON CHROMOSOME X dehydrogenase#PC00092 HUMAN|HGNC=25821|UniProtKB=Q96K58 Q96K58 ZNF668 PTHR24376:SF70 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 668 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13449|UniProtKB=Q9H156 Q9H156 SLITRK2 PTHR45773:SF4 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 2 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;generation of neurons#GO:0048699;cell part morphogenesis#GO:0032990 HUMAN|HGNC=42976|UniProtKB=Q6ZUA9 Q6ZUA9 MROH5 PTHR23120:SF6 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 5 HUMAN|HGNC=11539|UniProtKB=Q15542 Q15542 TAF5 PTHR19879:SF4 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5 molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110;RNA polymerase II general transcription initiation factor activity#GO:0016251 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;histone H3 acetylation#GO:0043966;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;histone acetylation#GO:0016573;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;RNA polymerase II, holoenzyme#GO:0016591;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;chromosome#GO:0005694;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=27397|UniProtKB=Q5JQC4 Q5JQC4 CT47A12 PTHR32157:SF8 GENE 6268-RELATED CANCER/TESTIS ANTIGEN 47A HUMAN|HGNC=21153|UniProtKB=Q8TEB7 Q8TEB7 RNF128 PTHR22765:SF30 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF128 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=24805|UniProtKB=Q86X60 Q86X60 FAM72B PTHR31841:SF1 PROTEIN FAM72A-RELATED PROTEIN FAM72A-RELATED cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=30295|UniProtKB=Q96S79 Q96S79 RASL10B PTHR46350:SF1 RAS LIKE FAMILY 10 MEMBER B-RELATED RAS-LIKE PROTEIN FAMILY MEMBER 10B HUMAN|HGNC=7170|UniProtKB=O75900 O75900 MMP23B PTHR10201:SF7 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-23 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=3661|UniProtKB=P02671 P02671 FGA PTHR47221:SF1 FIBRINOGEN ALPHA CHAIN FIBRINOGEN ALPHA CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component biogenesis#GO:0044085;regulation of MAPK cascade#GO:0043408;regulation of protein metabolic process#GO:0051246;positive regulation of signal transduction#GO:0009967;regulation of localization#GO:0032879;positive regulation of protein modification process#GO:0031401;regulation of apoptotic signaling pathway#GO:2001233;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;positive regulation of peptide hormone secretion#GO:0090277;secretion#GO:0046903;hormone transport#GO:0009914;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;protein-containing complex subunit organization#GO:0043933;regulation of peptide hormone secretion#GO:0090276;cellular protein-containing complex assembly#GO:0034622;regulation of multicellular organismal process#GO:0051239;negative regulation of coagulation#GO:0050819;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;cell adhesion#GO:0007155;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hormone secretion#GO:0046887;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell activation#GO:0001775;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;positive regulation of ERK1 and ERK2 cascade#GO:0070374;positive regulation of secretion by cell#GO:1903532;regulation of phosphorylation#GO:0042325;export from cell#GO:0140352;regulation of peptide transport#GO:0090087;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;platelet activation#GO:0030168;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;biological adhesion#GO:0022610;protein modification process#GO:0036211;MAPK cascade#GO:0000165;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;amide transport#GO:0042886;negative regulation of multicellular organismal process#GO:0051241;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;signal release#GO:0023061;protein metabolic process#GO:0019538;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;secretion by cell#GO:0032940;regulation of programmed cell death#GO:0043067;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;negative regulation of response to stimulus#GO:0048585;cell-cell adhesion#GO:0098609;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;hemostasis#GO:0007599;regulation of response to wounding#GO:1903034;positive regulation of protein metabolic process#GO:0051247;cell surface receptor signaling pathway#GO:0007166;regulation of cell death#GO:0010941;positive regulation of cell adhesion#GO:0045785;blood coagulation#GO:0007596;regulation of protein modification process#GO:0031399;regulation of cell-cell adhesion#GO:0022407;regulation of nitrogen compound metabolic process#GO:0051171;regulation of coagulation#GO:0050818;positive regulation of cellular metabolic process#GO:0031325;nitrogen compound transport#GO:0071705;homotypic cell-cell adhesion#GO:0034109;regulation of secretion by cell#GO:1903530;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of intracellular signal transduction#GO:1902531;regulation of phosphorus metabolic process#GO:0051174;regulation of wound healing#GO:0061041;hormone secretion#GO:0046879;protein activation cascade#GO:0072376;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of secretion#GO:0051046;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;positive regulation of secretion#GO:0051047;regulation of body fluid levels#GO:0050878;positive regulation of transport#GO:0051050;peptide transport#GO:0015833;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;response to wounding#GO:0009611;positive regulation of phosphate metabolic process#GO:0045937;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;transport#GO:0006810;positive regulation of peptide secretion#GO:0002793;protein-containing complex assembly#GO:0065003;wound healing#GO:0042060;peptide secretion#GO:0002790;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;platelet aggregation#GO:0070527;peptide hormone secretion#GO:0030072;regulation of hormone secretion#GO:0046883;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;regulation of cell adhesion#GO:0030155;metabolic process#GO:0008152;ERK1 and ERK2 cascade#GO:0070371;regulation of response to external stimulus#GO:0032101;regulation of apoptotic process#GO:0042981;regulation of response to stress#GO:0080134;regulation of hormone levels#GO:0010817;negative regulation of apoptotic process#GO:0043066;coagulation#GO:0050817;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular protein metabolic process#GO:0032268;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;negative regulation of blood coagulation#GO:0030195;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;protein polymerization#GO:0051258;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell-cell adhesion#GO:0022409 extracellular space#GO:0005615;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 Blood coagulation#P00011>Fibrinogen#P00406;Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin monomer#P00418;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443;Plasminogen activating cascade#P00050>Fibrin C-terminal truncation#P01258 HUMAN|HGNC=26291|UniProtKB=Q8TAM1 Q8TAM1 BBS10 PTHR14667:SF2 BARDET-BIEDL SYNDROME 10 PROTEIN BARDET-BIEDL SYNDROME 10 PROTEIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 HUMAN|HGNC=23290|UniProtKB=Q9H009 Q9H009 NACA2 PTHR21713:SF2 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA-2 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=23467|UniProtKB=A6NIR3 A6NIR3 AGAP5 PTHR45819:SF7 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 4-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=25463|UniProtKB=Q86WN1 Q86WN1 FCHSD1 PTHR15735:SF4 FCH AND DOUBLE SH3 DOMAINS PROTEIN F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 1 cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;synaptic signaling#GO:0099536;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;neuromuscular synaptic transmission#GO:0007274;regulation of protein polymerization#GO:0032271;cell-cell signaling#GO:0007267;signaling#GO:0023052;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;trans-synaptic signaling#GO:0099537;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 HUMAN|HGNC=15854|UniProtKB=Q9Y2F9 Q9Y2F9 BTBD3 PTHR45774:SF2 BTB/POZ DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN 3 head development#GO:0060322;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;dendrite development#GO:0016358;brain development#GO:0007420;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;dendrite morphogenesis#GO:0048813;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;forebrain development#GO:0030900;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=3721|UniProtKB=Q13451 Q13451 FKBP5 PTHR10516:SF26 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5 chaperone#PC00072 HUMAN|HGNC=29206|UniProtKB=Q9ULN7 Q9ULN7 PNMA8B PTHR23095:SF45 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 8B HUMAN|HGNC=4101|UniProtKB=P0DSO3 P0DSO3 GAGE4 PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=29101|UniProtKB=Q86XL3 Q86XL3 ANKLE2 PTHR12349:SF4 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=20874|UniProtKB=Q8IYI8 Q8IYI8 ZNF440 PTHR24381:SF311 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 440 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21397|UniProtKB=Q8N228 Q8N228 SCML4 PTHR12247:SF85 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 4 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=3662|UniProtKB=P02675 P02675 FGB PTHR19143:SF332 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN BETA CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 macromolecule metabolic process#GO:0043170;platelet activation#GO:0030168;biological adhesion#GO:0022610;organonitrogen compound metabolic process#GO:1901564;cell-cell adhesion#GO:0098609;regulation of body fluid levels#GO:0050878;homotypic cell-cell adhesion#GO:0034109;wound healing#GO:0042060;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;hemostasis#GO:0007599;coagulation#GO:0050817;primary metabolic process#GO:0044238;cell activation#GO:0001775;response to stimulus#GO:0050896;protein activation cascade#GO:0072376;response to wounding#GO:0009611;response to stress#GO:0006950;platelet aggregation#GO:0070527;regulation of biological quality#GO:0065008;cell-matrix adhesion#GO:0007160;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Blood coagulation#P00011>Fibrinogen#P00406;Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin monomer#P00418;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443 HUMAN|HGNC=11121|UniProtKB=O60906 O60906 SMPD2 PTHR12393:SF6 SPHINGOMYELIN PHOSPHODIESTERASE RELATED SPHINGOMYELIN PHOSPHODIESTERASE 2 phosphodiesterase#PC00185 HUMAN|HGNC=12118|UniProtKB=A0A0B4J279 A0A0B4J279 TRAV21 PTHR19433:SF52 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 21 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=14244|UniProtKB=Q9NP72 Q9NP72 RAB18 PTHR24073:SF285 DRAB5-RELATED RAS-RELATED PROTEIN RAB-18 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=18274|UniProtKB=Q9NS75 Q9NS75 CYSLTR2 PTHR24230:SF10 G-PROTEIN COUPLED RECEPTOR CYSTEINYL LEUKOTRIENE RECEPTOR 2 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=18081|UniProtKB=Q9Y5W5 Q9Y5W5 WIF1 PTHR14949:SF32 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 WNT INHIBITORY FACTOR 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 anatomical structure development#GO:0048856;developmental process#GO:0032502 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=49601|UniProtKB=A0A0B4J2H0 A0A0B4J2H0 IGHV1-69D PTHR23266:SF262 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-69-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=14695|UniProtKB=Q8NGV5 Q8NGV5 OR13D1 PTHR26453:SF0 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13D1 transmembrane signal receptor#PC00197 HUMAN|HGNC=13539|UniProtKB=Q6RW13 Q6RW13 AGTRAP PTHR16521:SF3 TYPE-1 ANGIOTENSIN II RECEPTOR-ASSOCIATED PROTEIN TYPE-1 ANGIOTENSIN II RECEPTOR-ASSOCIATED PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=12450|UniProtKB=P17643 P17643 TYRP1 PTHR11474:SF3 TYROSINASE FAMILY MEMBER 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID OXIDASE cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;developmental pigmentation#GO:0048066;organelle organization#GO:0006996;melanosome organization#GO:0032438;developmental process#GO:0032502;pigmentation#GO:0043473;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;melanocyte differentiation#GO:0030318 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=11073|UniProtKB=P48764 P48764 SLC9A3 PTHR10110:SF90 SODIUM/HYDROGEN EXCHANGER SODIUM/HYDROGEN EXCHANGER 3 microvillus#GO:0005902;supramolecular complex#GO:0099080;brush border#GO:0005903;actin filament bundle#GO:0032432;cluster of actin-based cell projections#GO:0098862;actin-based cell projection#GO:0098858;cell projection membrane#GO:0031253;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=1366|UniProtKB=Q76LX8 Q76LX8 ADAMTS13 PTHR13723:SF20 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 13 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=33159|UniProtKB=Q3I5F7 Q3I5F7 ACOT6 PTHR10824:SF17 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COENZYME A THIOESTERASE 6-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 esterase#PC00097 HUMAN|HGNC=17040|UniProtKB=O15234 O15234 CASC3 PTHR13434:SF0 PROTEIN CASC3 PROTEIN CASC3 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7655|UniProtKB=P61601 P61601 NCALD PTHR23055:SF87 CALCIUM BINDING PROTEINS NEUROCALCIN-DELTA HUMAN|HGNC=4650|UniProtKB=P29083 P29083 GTF2E1 PTHR13097:SF7 TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;protein-DNA complex subunit organization#GO:0071824;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TFIIE#P00666;General transcription regulation#P00023>TFIIEalpha#P00669;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395;Transcription regulation by bZIP transcription factor#P00055>TFIIEalpha#P01398 HUMAN|HGNC=25285|UniProtKB=Q5GAN3 Q5GAN3 RNASE13 PTHR11437:SF11 RIBONUCLEASE INACTIVE RIBONUCLEASE-LIKE PROTEIN 13-RELATED HUMAN|HGNC=2843|UniProtKB=O75907 O75907 DGAT1 PTHR10408:SF7 STEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 acyltransferase#PC00042 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 HUMAN|HGNC=14529|UniProtKB=Q6BEB4 Q6BEB4 SP5 PTHR23235:SF29 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11734|UniProtKB=Q9BXU0 Q9BXU0 TEX12 PTHR37349:SF1 TESTIS-EXPRESSED PROTEIN 12 TESTIS-EXPRESSED PROTEIN 12 HUMAN|HGNC=28111|UniProtKB=Q8IZ81 Q8IZ81 ELMOD2 PTHR12771:SF47 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 cellular anatomical entity#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 HUMAN|HGNC=33719|UniProtKB=Q5SNT2 Q5SNT2 TMEM201 PTHR28646:SF1 TRANSMEMBRANE PROTEIN 201 TRANSMEMBRANE PROTEIN 201 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 nuclear migration#GO:0007097;cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;establishment of organelle localization#GO:0051656;nucleus localization#GO:0051647 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=6251|UniProtKB=Q12809 Q12809 KCNH2 PTHR10217:SF506 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 blood circulation#GO:0008015;monovalent inorganic cation transport#GO:0015672;regulation of multicellular organismal process#GO:0051239;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of heart contraction#GO:0008016;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;heart contraction#GO:0060047;regulation of system process#GO:0044057;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;circulatory system process#GO:0003013;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;multicellular organismal process#GO:0032501;signaling#GO:0023052;heart process#GO:0003015;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=29663|UniProtKB=Q1L6U9 Q1L6U9 MSMP PTHR10500:SF4 BETA-MICROSEMINOPROTEIN PROSTATE-ASSOCIATED MICROSEMINOPROTEIN intercellular signal molecule#PC00207 HUMAN|HGNC=19041|UniProtKB=Q96D53 Q96D53 COQ8B PTHR43851:SF4 FAMILY NOT NAMED ATYPICAL KINASE COQ8B, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;small molecule biosynthetic process#GO:0044283;ubiquinone biosynthetic process#GO:0006744;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=24368|UniProtKB=Q9UII4 Q9UII4 HERC5 PTHR45622:SF7 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 ISG15--PROTEIN LIGASE HERC5 transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of immune system process#GO:0002682;defense response to virus#GO:0051607;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;immune effector process#GO:0002252;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of response to external stimulus#GO:0032101;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to biotic stimulus#GO:0002831;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of defense response#GO:0031347;biological regulation#GO:0065007 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9514|UniProtKB=P11464 P11464 PSG1 PTHR44427:SF16 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 1 HUMAN|HGNC=9571|UniProtKB=Q92530 Q92530 PSMF1 PTHR13266:SF1 PROTEASOME INHIBITOR PROTEASOME INHIBITOR PI31 SUBUNIT macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protease inhibitor#PC00191 HUMAN|HGNC=5389|UniProtKB=P22304 P22304 IDS PTHR45953:SF1 IDURONATE 2-SULFATASE IDURONATE 2-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 HUMAN|HGNC=20860|UniProtKB=Q504Y0 Q504Y0 SLC39A12 PTHR12191:SF4 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP12 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=5208|UniProtKB=P28845 P28845 HSD11B1 PTHR44279:SF1 HYDROXYSTEROID (11-BETA) DEHYDROGENASE 1-LIKE B-RELATED CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1 lipid binding#GO:0008289;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;steroid binding#GO:0005496 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;steroid catabolic process#GO:0006706;organic cyclic compound metabolic process#GO:1901360;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;lipid catabolic process#GO:0016042;organic substance catabolic process#GO:1901575;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092 HUMAN|HGNC=5118|UniProtKB=P09629 P09629 HOXB7 PTHR45659:SF11 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=14893|UniProtKB=Q9BZM6 Q9BZM6 ULBP1 PTHR16675:SF268 MHC CLASS I-RELATED UL16-BINDING PROTEIN 1 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=30846|UniProtKB=Q7RTY8 Q7RTY8 TMPRSS7 PTHR24253:SF103 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 7 serine protease#PC00203 HUMAN|HGNC=8983|UniProtKB=P42356 P42356 PI4KA PTHR10048:SF15 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE ALPHA-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;phosphatidylinositol phosphorylation#GO:0046854;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 kinase#PC00137 HUMAN|HGNC=320|UniProtKB=Q15109 Q15109 AGER PTHR11973:SF20 CELL SURFACE GLYCOPROTEIN MUC18-RELATED ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=1298|UniProtKB=Q9H0A9 Q9H0A9 SPATC1L PTHR22192:SF1 SPERIOLIN SPERIOLIN-LIKE PROTEIN intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=8466|UniProtKB=Q8NG99 Q8NG99 OR7G2 PTHR48001:SF96 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7G2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=13339|UniProtKB=O95239 O95239 KIF4A PTHR47969:SF18 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED CHROMOSOME-ASSOCIATED KINESIN KIF4A mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 microtubule binding motor protein#PC00156 HUMAN|HGNC=13600|UniProtKB=Q9UKT6 Q9UKT6 FBXL21P PTHR16134:SF2 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX/LRR-REPEAT PROTEIN 21-RELATED rhythmic process#GO:0048511;mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;mitotic cell cycle process#GO:1903047;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;proteasomal protein catabolic process#GO:0010498;response to abiotic stimulus#GO:0009628;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;response to light stimulus#GO:0009416;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;G2/M transition of mitotic cell cycle#GO:0000086;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of circadian rhythm#GO:0042752;cell cycle G2/M phase transition#GO:0044839 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=268|UniProtKB=P0DMS8 P0DMS8 ADORA3 PTHR24246:SF2 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A3 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 HUMAN|HGNC=18956|UniProtKB=Q969S2 Q969S2 NEIL2 PTHR22993:SF9 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA glycosylase#PC00010 HUMAN|HGNC=13053|UniProtKB=P17031 P17031 ZNF26 PTHR24377:SF232 IP01015P-RELATED ZINC FINGER PROTEIN 26 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=13561|UniProtKB=Q5T1R4 Q5T1R4 HIVEP3 PTHR45944:SF5 SCHNURRI, ISOFORM F TRANSCRIPTION FACTOR HIVEP3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11048|UniProtKB=P23975 P23975 SLC6A2 PTHR11616:SF300 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NORADRENALINE TRANSPORTER localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>NET#P00064 HUMAN|HGNC=15674|UniProtKB=Q9BWW4 Q9BWW4 SSBP3 PTHR12610:SF22 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 3 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 HUMAN|HGNC=6903|UniProtKB=Q00266 Q00266 MAT1A PTHR11964:SF11 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotidyltransferase#PC00174 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 HUMAN|HGNC=4331|UniProtKB=O94925 O94925 GLS PTHR12544:SF49 GLUTAMINASE GLUTAMINASE KIDNEY ISOFORM, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 hydrolase#PC00121 HUMAN|HGNC=24130|UniProtKB=Q86XR2 Q86XR2 NIBAN3 PTHR14392:SF4 NIBAN FAMILY MEMBER PROTEIN NIBAN 3 HUMAN|HGNC=14678|UniProtKB=Q96CX2 Q96CX2 KCTD12 PTHR14499:SF29 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD12 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of G protein-coupled receptor signaling pathway#GO:0008277;cellular process#GO:0009987;signaling#GO:0023052 presynapse#GO:0098793;synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=30729|UniProtKB=Q8WYN3 Q8WYN3 CSRNP3 PTHR13580:SF13 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE/SERINE-RICH NUCLEAR PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=5229|UniProtKB=P31689 P31689 DNAJA1 PTHR43888:SF8 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 1 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=4519|UniProtKB=Q15743 Q15743 GPR68 PTHR24234:SF5 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR OVARIAN CANCER G-PROTEIN COUPLED RECEPTOR 1 cellular response to abiotic stimulus#GO:0071214;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to environmental stimulus#GO:0104004 G-protein coupled receptor#PC00021 HUMAN|HGNC=29579|UniProtKB=Q8TC71 Q8TC71 SPATA18 PTHR21771:SF0 MITOCHONDRIA-EATING PROTEIN-RELATED MITOCHONDRIA-EATING PROTEIN macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;autophagy#GO:0006914;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=4610|UniProtKB=Q12849 Q12849 GRSF1 PTHR13976:SF42 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED G-RICH SEQUENCE FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=7886|UniProtKB=P51513 P51513 NOVA1 PTHR10288:SF229 KH DOMAIN CONTAINING RNA BINDING PROTEIN RNA-BINDING PROTEIN NOVA-1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=19129|UniProtKB=Q9Y617 Q9Y617 PSAT1 PTHR43247:SF5 PHOSPHOSERINE AMINOTRANSFERASE PHOSPHOSERINE AMINOTRANSFERASE transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;transaminase activity#GO:0008483;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transaminase#PC00216 Pyridoxal-5-phosphate biosynthesis#P02759>Phosphohydroxythreonine aminotransferase#P03058;Vitamin B6 metabolism#P02787>Phosphoserine transaminase#P03227;Serine glycine biosynthesis#P02776>Phosphoserine aminotransferase#P03157 HUMAN|HGNC=4185|UniProtKB=Q14549 Q14549 GBX1 PTHR24334:SF2 HOMEOBOX PROTEIN GBX HOMEOBOX PROTEIN GBX-1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;regulation of multicellular organismal process#GO:0051239;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;brain development#GO:0007420;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=12690|UniProtKB=P09327 P09327 VIL1 PTHR11977:SF35 VILLIN VILLIN-1 cytoskeletal protein binding#GO:0008092;phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;actin binding#GO:0003779 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;cell projection organization#GO:0030030;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of actin polymerization or depolymerization#GO:0008064;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;negative regulation of cellular component organization#GO:0051129;cell part morphogenesis#GO:0032990;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;cellular component morphogenesis#GO:0032989;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;negative regulation of actin filament polymerization#GO:0030837;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;cell leading edge#GO:0031252;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 HUMAN|HGNC=9879|UniProtKB=Q7LDG7 Q7LDG7 RASGRP2 PTHR23113:SF16 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 2 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 HUMAN|HGNC=1149|UniProtKB=O60566 O60566 BUB1B PTHR14030:SF4 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;catalytic activity#GO:0003824;protein kinase activity#GO:0004672 negative regulation of sister chromatid segregation#GO:0033046;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of mitotic sister chromatid segregation#GO:0033047;reproductive process#GO:0022414;negative regulation of cellular component organization#GO:0051129;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;mitotic cell cycle phase transition#GO:0044772;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;meiotic sister chromatid segregation#GO:0045144;mitotic cell cycle process#GO:1903047;sister chromatid cohesion#GO:0007062;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;mitotic spindle assembly checkpoint#GO:0007094;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;mitotic cell cycle checkpoint#GO:0007093;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;metaphase/anaphase transition of cell cycle#GO:0044784;negative regulation of chromosome separation#GO:1905819;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome kinetochore#GO:0000777;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;condensed nuclear chromosome kinetochore#GO:0000778;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=31456|UniProtKB=Q5TBE3 Q5TBE3 C9orf153 PTHR37353:SF1 RIKEN CDNA 4921517D22 GENE RIKEN CDNA 4921517D22 GENE HUMAN|HGNC=5113|UniProtKB=P14652 P14652 HOXB2 PTHR45664:SF7 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=7230|UniProtKB=P49959 P49959 MRE11 PTHR10139:SF4 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;endodeoxyribonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;deoxyribonuclease activity#GO:0004536 DNA repair#GO:0006281;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;organic substance metabolic process#GO:0071704;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;mitotic DNA integrity checkpoint#GO:0044774;cell cycle phase transition#GO:0044770;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;double-strand break repair via nonhomologous end joining#GO:0006303;G2/M transition of mitotic cell cycle#GO:0000086;response to stress#GO:0006950;reproduction#GO:0000003;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;cellular response to stress#GO:0033554;cell cycle G2/M phase transition#GO:0044839;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;double-strand break repair#GO:0006302;mitotic cell cycle phase transition#GO:0044772;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;intra-S DNA damage checkpoint#GO:0031573;mitotic cell cycle process#GO:1903047;telomere maintenance#GO:0000723;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;G2 DNA damage checkpoint#GO:0031572;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;mitotic DNA damage checkpoint#GO:0044773;homeostatic process#GO:0042592;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;non-recombinational repair#GO:0000726;meiotic DNA double-strand break formation#GO:0042138;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;mitotic G2 DNA damage checkpoint#GO:0007095;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;nuclear chromosome, telomeric region#GO:0000784;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;chromosomal region#GO:0098687 HUMAN|HGNC=20637|UniProtKB=Q9BPU6 Q9BPU6 DPYSL5 PTHR11647:SF58 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 5 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125;Axon guidance mediated by semaphorins#P00007>CRAM#P00330 HUMAN|HGNC=28673|UniProtKB=Q9BSK1 Q9BSK1 ZNF577 PTHR24377:SF900 IP01015P-RELATED ZINC FINGER PROTEIN 577 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=6291|UniProtKB=Q9H2S1 Q9H2S1 KCNN2 PTHR10153:SF43 SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;calmodulin binding#GO:0005516;transporter activity#GO:0005215;channel activity#GO:0015267;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuron projection#GO:0043005;neuronal cell body#GO:0043025;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=4495|UniProtKB=O43193 O43193 MLNR PTHR24243:SF3 G-PROTEIN COUPLED RECEPTOR MOTILIN RECEPTOR G-protein coupled receptor#PC00021 HUMAN|HGNC=17296|UniProtKB=Q7LG56 Q7LG56 RRM2B PTHR23409:SF19 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 B oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909 HUMAN|HGNC=10926|UniProtKB=O15375 O15375 SLC16A5 PTHR11360:SF21 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 6 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=14592|UniProtKB=Q7Z628 Q7Z628 NET1 PTHR46006:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A NEUROEPITHELIAL CELL-TRANSFORMING GENE 1 PROTEIN Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;Rho protein signal transduction#GO:0007266;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of Ras protein signal transduction#GO:0046578 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=8264|UniProtKB=Q8NGT1 Q8NGT1 OR2K2 PTHR26453:SF198 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2K2 transmembrane signal receptor#PC00197 HUMAN|HGNC=4555|UniProtKB=P22352 P22352 GPX3 PTHR11592:SF32 GLUTATHIONE PEROXIDASE GPX6 PROTEIN-RELATED oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;binding#GO:0005488;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180 HUMAN|HGNC=1617|UniProtKB=P50991 P50991 CCT4 PTHR11353:SF26 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT DELTA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 chaperonin#PC00073 HUMAN|HGNC=6665|UniProtKB=Q08397 Q08397 LOXL1 PTHR45817:SF8 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175 HUMAN|HGNC=1729|UniProtKB=P21127 P21127 CDK11B PTHR24056:SF107 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 11A-RELATED cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;gene expression#GO:0010467;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=23798|UniProtKB=Q8TD91 Q8TD91 MAGEC3 PTHR11736:SF86 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN C3 scaffold/adaptor protein#PC00226 HUMAN|HGNC=14361|UniProtKB=P78411 P78411 IRX5 PTHR11211:SF17 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=21919|UniProtKB=Q9H0J9 Q9H0J9 PARP12 PTHR45740:SF6 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP12 HUMAN|HGNC=8170|UniProtKB=Q8NGC3 Q8NGC3 OR10G2 PTHR26453:SF88 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G2 transmembrane signal receptor#PC00197 HUMAN|HGNC=10925|UniProtKB=O15374 O15374 SLC16A4 PTHR11360:SF14 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 5 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=2550|UniProtKB=O95319 O95319 CELF2 PTHR24012:SF699 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 HUMAN|HGNC=9200|UniProtKB=O00411 O00411 POLRMT PTHR10102:SF0 DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438 mitochondrial protein complex#GO:0098798;cytoplasm#GO:0005737;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=11870|UniProtKB=P82094 P82094 TMF1 PTHR46515:SF1 TATA ELEMENT MODULATORY FACTOR TMF1 TATA ELEMENT MODULATORY FACTOR cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=11114|UniProtKB=P41229 P41229 KDM5C PTHR10694:SF43 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5C demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=23723|UniProtKB=Q5T4B2 Q5T4B2 CERCAM PTHR10730:SF9 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER INACTIVE GLYCOSYLTRANSFERASE 25 FAMILY MEMBER 3 transferase activity, transferring hexosyl groups#GO:0016758;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 protein modifying enzyme#PC00260 HUMAN|HGNC=12970|UniProtKB=Q9UJW8 Q9UJW8 ZNF180 PTHR24381:SF27 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 180 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=10589|UniProtKB=O60939 O60939 SCN2B PTHR13869:SF3 MYELIN P0 RELATED SODIUM CHANNEL SUBUNIT BETA-2 myelin protein#PC00161 HUMAN|HGNC=18896|UniProtKB=Q9H7F4 Q9H7F4 TMEM185B PTHR13568:SF5 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 185B HUMAN|HGNC=2892|UniProtKB=Q9UBU2 Q9UBU2 DKK2 PTHR12113:SF12 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=243|UniProtKB=P35611 P35611 ADD1 PTHR10672:SF4 ADDUCIN ALPHA-ADDUCIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of multicellular organismal process#GO:0051239;regulation of organelle organization#GO:0033043;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of actin filament polymerization#GO:0030837;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;epithelium development#GO:0060429;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;cellular component disassembly#GO:0022411;regulation of protein-containing complex assembly#GO:0043254;regulation of epithelial cell differentiation#GO:0030856;negative regulation of organelle organization#GO:0010639;supramolecular fiber organization#GO:0097435;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;cell-cell junction organization#GO:0045216;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;regulation of actin filament length#GO:0030832;actin filament bundle assembly#GO:0051017;multicellular organism development#GO:0007275;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;tissue development#GO:0009888;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;cell junction organization#GO:0034330;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;actin cytoskeleton organization#GO:0030036 plasma membrane raft#GO:0044853;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;asymmetric synapse#GO:0032279;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;focal adhesion#GO:0005925;plasma membrane region#GO:0098590;cell-substrate junction#GO:0030055;adherens junction#GO:0005912;postsynapse#GO:0098794;membrane raft#GO:0045121;cytoskeleton#GO:0005856;membrane region#GO:0098589;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 HUMAN|HGNC=12591|UniProtKB=P06132 P06132 UROD PTHR21091:SF169 METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED UROPORPHYRINOGEN DECARBOXYLASE methyltransferase#PC00155 Heme biosynthesis#P02746>Uroporphyrinogen decarboxylase#P02975 HUMAN|HGNC=25367|UniProtKB=Q9H0W5 Q9H0W5 CCDC8 PTHR47741:SF1 COILED COIL DOMAIN-CONTAINING PROTEIN 8, CCDC8 COILED-COIL DOMAIN-CONTAINING PROTEIN 8 HUMAN|HGNC=3581|UniProtKB=Q12830 Q12830 BPTF PTHR45975:SF2 NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF cis-regulatory region sequence-specific DNA binding#GO:0000987;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;methylated histone binding#GO:0035064;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;nucleosome organization#GO:0034728;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;protein-DNA complex subunit organization#GO:0071824;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of nucleic acid-templated transcription#GO:1903506;chromatin remodeling#GO:0006338;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=27820|UniProtKB=Q86XE3 Q86XE3 MICU3 PTHR12294:SF10 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 3, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;mitochondrial calcium ion homeostasis#GO:0051560;mitochondrial transmembrane transport#GO:1990542;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;mitochondrial transport#GO:0006839;cellular chemical homeostasis#GO:0055082;mitochondrial calcium ion transmembrane transport#GO:0006851;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;ion channel complex#GO:0034702;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cation channel complex#GO:0034703;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 calmodulin-related#PC00061 HUMAN|HGNC=29315|UniProtKB=Q9HCJ6 Q9HCJ6 VAT1L PTHR44054:SF2 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE Huntington disease#P00029>PIG3#G01535 HUMAN|HGNC=11444|UniProtKB=P61764 P61764 STXBP1 PTHR11679:SF35 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 1 syntaxin binding#GO:0019905;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488;syntaxin-1 binding#GO:0017075 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of neurotransmitter levels#GO:0001505;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;export from cell#GO:0140352 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Munc18#P05770 HUMAN|HGNC=11106|UniProtKB=Q96GM5 Q96GM5 SMARCD1 PTHR13844:SF1 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;protein-containing complex disassembly#GO:0032984;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=2039|UniProtKB=P56856 P56856 CLDN18 PTHR12002:SF9 CLAUDIN CLAUDIN-18 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=20263|UniProtKB=Q96T68 Q96T68 SETDB2 PTHR46024:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS HISTONE-LYSINE N-METHYLTRANSFERASE SETDB2 N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;histone methylation#GO:0016571;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of chromatin assembly or disassembly#GO:0001672;protein alkylation#GO:0008213;transcription, DNA-templated#GO:0006351;protein methylation#GO:0006479;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of chromatin organization#GO:1902275;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;macromolecule methylation#GO:0043414;heterochromatin organization#GO:0070828;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of chromatin assembly#GO:0010847;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;negative regulation of biological process#GO:0048519;positive regulation of organelle organization#GO:0010638;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of cellular component biogenesis#GO:0044089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;peptidyl-lysine methylation#GO:0018022;negative regulation of biosynthetic process#GO:0009890;heterochromatin assembly#GO:0031507;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;histone lysine methylation#GO:0034968;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=13436|UniProtKB=Q96KN7 Q96KN7 RPGRIP1 PTHR14240:SF3 RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN 1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488 non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;sensory system development#GO:0048880;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;anatomical structure development#GO:0048856;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;animal organ development#GO:0048513;developmental process#GO:0032502;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;retina development in camera-type eye#GO:0060041;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;protein localization to organelle#GO:0033365;visual system development#GO:0150063;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cell development#GO:0048468;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;camera-type eye development#GO:0043010;generation of neurons#GO:0048699 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=13079|UniProtKB=Q96NJ3 Q96NJ3 ZNF285 PTHR24377:SF958 IP01015P-RELATED ZINC FINGER PROTEIN 285 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4857|UniProtKB=Q00341 Q00341 HDLBP PTHR10627:SF34 SCP160 VIGILIN nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;polysome#GO:0005844;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=2380|UniProtKB=P10915 P10915 HAPLN1 PTHR22804:SF10 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 1 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=10930|UniProtKB=O00624 O00624 SLC17A2 PTHR11662:SF193 SOLUTE CARRIER FAMILY 17 SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=14523|UniProtKB=Q96MW7 Q96MW7 TIGD1 PTHR19303:SF26 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 HUMAN|HGNC=11829|UniProtKB=O95049 O95049 TJP3 PTHR13865:SF11 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN ZO-3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 blood circulation#GO:0008015;cell-cell junction organization#GO:0045216;cellular developmental process#GO:0048869;macromolecule localization#GO:0033036;epithelium development#GO:0060429;system process#GO:0003008;developmental process#GO:0032502;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;homeostatic process#GO:0042592;cell adhesion#GO:0007155;cellular component organization#GO:0016043;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;circulatory system process#GO:0003013;tissue development#GO:0009888;protein localization#GO:0008104;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;multicellular organismal homeostasis#GO:0048871;tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446;anatomical structure homeostasis#GO:0060249 anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical junction complex#GO:0043296 tight junction#PC00214 HUMAN|HGNC=21091|UniProtKB=Q9Y4E5 Q9Y4E5 ZNF451 PTHR24403:SF52 ZINC FINGER PROTEIN E3 SUMO-PROTEIN LIGASE ZNF451 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;transcription corepressor activity#GO:0003714;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;molecular function regulator#GO:0098772;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription, initiation#GO:2000142;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of transcription initiation from RNA polymerase II promoter#GO:0060260;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25148|UniProtKB=Q8NEG4 Q8NEG4 FAM83F PTHR16181:SF19 UNCHARACTERIZED PROTEIN FAM83F HUMAN|HGNC=12569|UniProtKB=O95185 O95185 UNC5C PTHR12582:SF7 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5C transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 HUMAN|HGNC=24011|UniProtKB=Q9NYB9 Q9NYB9 ABI2 PTHR10460:SF26 ABL INTERACTOR FAMILY MEMBER ABL INTERACTOR 2 protein binding#GO:0005515;binding#GO:0005488 cell leading edge#GO:0031252;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=44141|UniProtKB=P0DJR0 P0DJR0 GIMD1 PTHR10903:SF103 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER GIMD1 small GTPase#PC00208 HUMAN|HGNC=7137|UniProtKB=P55196 P55196 AFDN PTHR10398:SF2 AFADIN AFADIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;macromolecule localization#GO:0033036;regulation of protein localization#GO:0032880;protein localization#GO:0008104 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 non-motor actin binding protein#PC00165 Alzheimer disease-presenilin pathway#P00004>Afadin#P00146 HUMAN|HGNC=49416|UniProtKB=H0YKK7 H0YKK7 GOLGA6L19 PTHR23143:SF19 TRICHOHYALIN-RELATED GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 10-RELATED actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=4428|UniProtKB=Q8TBA6 Q8TBA6 GOLGA5 PTHR13815:SF7 GOLGIN-84 GOLGIN SUBFAMILY A MEMBER 5 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization#GO:0051234;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=11254|UniProtKB=O43791 O43791 SPOP PTHR24413:SF97 SPECKLE-TYPE POZ PROTEIN SPECKLE-TYPE POZ PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=18384|UniProtKB=Q96QR1 Q96QR1 SCGB3A1 PTHR34829:SF1 SECRETOGLOBIN FAMILY 3A MEMBER 2 SECRETOGLOBIN FAMILY 3A MEMBER 1 cellular developmental process#GO:0048869;plasma membrane fusion#GO:0045026;muscle cell differentiation#GO:0042692;positive regulation of cell differentiation#GO:0045597;regulation of anatomical structure morphogenesis#GO:0022603;membrane organization#GO:0061024;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987;cell-cell fusion#GO:0140253;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;muscle structure development#GO:0061061;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;syncytium formation by plasma membrane fusion#GO:0000768;membrane fusion#GO:0061025;syncytium formation#GO:0006949;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of biological process#GO:0048518 HUMAN|HGNC=5870|UniProtKB=P15814 P15814 IGLL1 PTHR23266:SF349 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA-LIKE POLYPEPTIDE 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=11039|UniProtKB=Q9NY91 Q9NY91 SLC5A4 PTHR11819:SF112 SOLUTE CARRIER FAMILY 5 SOLUTE CARRIER FAMILY 5 MEMBER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sugar transmembrane transporter activity#GO:0051119;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=33747|UniProtKB=Q8TAL6 Q8TAL6 FIBIN PTHR31185:SF0 FIN BUD INITIATION FACTOR FIBIN FIN BUD INITIATION FACTOR HOMOLOG HUMAN|HGNC=7193|UniProtKB=O96007 O96007 MOCS2 PTHR23404:SF2 MOLYBDOPTERIN SYNTHASE RELATED MOLYBDOPTERIN SYNTHASE CATALYTIC SUBUNIT cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=4620|UniProtKB=P06396 P06396 GSN PTHR11977:SF29 VILLIN GELSOLIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 HUMAN|HGNC=27356|UniProtKB=P0DJ93 P0DJ93 SMIM13 PTHR36877:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 13 SMALL INTEGRAL MEMBRANE PROTEIN 13 HUMAN|HGNC=10013|UniProtKB=Q15835 Q15835 GRK1 PTHR24355:SF11 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RHODOPSIN KINASE GRK1 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin kinase#P00750;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 HUMAN|HGNC=9255|UniProtKB=P23284 P23284 PPIB PTHR11071:SF477 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=4616|UniProtKB=P49840 P49840 GSK3A PTHR24057:SF14 GLYCOGEN SYNTHASE KINASE-3 ALPHA GLYCOGEN SYNTHASE KINASE-3 ALPHA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;programmed cell death#GO:0012501;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;apoptotic signaling pathway#GO:0097190;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;negative regulation of signal transduction#GO:0009968;neuron development#GO:0048666;multicellular organismal process#GO:0032501;negative regulation of Wnt signaling pathway#GO:0030178;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cellular response to nitrogen compound#GO:1901699;system development#GO:0048731;cell differentiation#GO:0030154;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;response to peptide#GO:1901652;cell death#GO:0008219;neuron differentiation#GO:0030182;cellular response to insulin stimulus#GO:0032869;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of TOR signaling#GO:0032006;cell development#GO:0048468;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;extrinsic apoptotic signaling pathway#GO:0097191;regulation of developmental process#GO:0050793;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of canonical Wnt signaling pathway#GO:0090090;generation of neurons#GO:0048699 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;intracellular#GO:0005622;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GSK#P00714;Ras Pathway#P04393>GSK3#P04546;PDGF signaling pathway#P00047>GSK3#P01153 HUMAN|HGNC=10830|UniProtKB=Q99961 Q99961 SH3GL1 PTHR14167:SF63 SH3 DOMAIN-CONTAINING ENDOPHILIN-A2 HUMAN|HGNC=11697|UniProtKB=P63172 P63172 DYNLT1 PTHR21255:SF19 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 1 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=1516|UniProtKB=P04040 P04040 CAT PTHR11465:SF9 CATALASE CATALASE binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 response to stimulus#GO:0050896;response to inorganic substance#GO:0010035;response to stress#GO:0006950;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;response to oxidative stress#GO:0006979;cellular process#GO:0009987;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 peroxidase#PC00180 HUMAN|HGNC=18967|UniProtKB=Q92611 Q92611 EDEM1 PTHR45679:SF5 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1 HUMAN|HGNC=22944|UniProtKB=P59044 P59044 NLRP6 PTHR45690:SF1 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 6 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 HUMAN|HGNC=3701|UniProtKB=P49789 P49789 FHIT PTHR46981:SF1 BIS(5'-ADENOSYL)-TRIPHOSPHATASE BIS(5'-ADENOSYL)-TRIPHOSPHATASE pyrophosphatase activity#GO:0016462;nucleotide diphosphatase activity#GO:0004551;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;enzyme binding#GO:0019899;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ubiquitin protein ligase binding#GO:0031625 negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;proteolysis#GO:0006508;apoptotic process#GO:0006915;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;purine nucleotide metabolic process#GO:0006163;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;nucleoside phosphate catabolic process#GO:1901292;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cell communication#GO:0007154;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of proteolysis#GO:0045861;negative regulation of nitrogen compound metabolic process#GO:0051172;organophosphate catabolic process#GO:0046434;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;negative regulation of protein catabolic process#GO:0042177;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;biosynthetic process#GO:0009058;signal transduction by p53 class mediator#GO:0072331;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;negative regulation of proteasomal protein catabolic process#GO:1901799;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of proteolysis involved in cellular protein catabolic process#GO:1903051;cell death#GO:0008219;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;signaling#GO:0023052;regulation of cellular protein catabolic process#GO:1903362;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;regulation of cellular catabolic process#GO:0031329;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of catabolic process#GO:0009895;negative regulation of cellular protein catabolic process#GO:1903363;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=24218|UniProtKB=Q03701 Q03701 CEBPZ PTHR12048:SF0 CCAAT-BINDING FACTOR-RELATED CCAAT/ENHANCER-BINDING PROTEIN ZETA membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=1956|UniProtKB=Q15822 Q15822 CHRNA2 PTHR18945:SF757 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;acetylcholine receptor activity#GO:0015464;molecular transducer activity#GO:0060089;acetylcholine binding#GO:0042166;ion binding#GO:0043167;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=17850|UniProtKB=Q9BQA5 Q9BQA5 HINFP PTHR24391:SF26 HISTONE H4 TRANSCRIPTION FACTOR-RELATED HISTONE H4 TRANSCRIPTION FACTOR C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=12759|UniProtKB=Q9P2S5 Q9P2S5 WRAP73 PTHR16220:SF0 WD REPEAT PROTEIN 8-RELATED WD REPEAT-CONTAINING PROTEIN WRAP73 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;mitotic spindle organization#GO:0007052;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule anchoring#GO:0034453;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;protein localization to organelle#GO:0033365;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;protein localization to cytoskeleton#GO:0044380;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;organelle fission#GO:0048285 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229 HUMAN|HGNC=2568|UniProtKB=Q13495 Q13495 MAMLD1 PTHR15275:SF1 CG1 PROTEIN/F18 MASTERMIND-LIKE DOMAIN-CONTAINING PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 HUMAN|HGNC=37490|UniProtKB=E9PQR5 E9PQR5 NPIPB8 PTHR15438:SF4 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER B15-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=2901|UniProtKB=Q15700 Q15700 DLG2 PTHR23119:SF6 DISCS LARGE DISKS LARGE HOMOLOG 2 establishment or maintenance of cell polarity#GO:0007163;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;developmental process#GO:0032502;biological adhesion#GO:0022610;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;signaling#GO:0023052;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;multicellular organismal process#GO:0032501;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;neuromuscular junction#GO:0031594;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;basolateral plasma membrane#GO:0016323;ion channel complex#GO:0034702;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6029|UniProtKB=P15248 P15248 IL9 PTHR16926:SF1 INTERLEUKIN 9 INTERLEUKIN-9 interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Interleukin#P00970 HUMAN|HGNC=7702|UniProtKB=P17568 P17568 NDUFB7 PTHR20900:SF0 NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=5888|UniProtKB=P01704 P01704 IGLV2-14 PTHR23267:SF407 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 2-14-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=9921|UniProtKB=P10745 P10745 RBP3 PTHR11261:SF3 INTERPHOTORECEPTOR RETINOID-BINDING PROTEIN RETINOL-BINDING PROTEIN 3 HUMAN|HGNC=24637|UniProtKB=Q8IXB1 Q8IXB1 DNAJC10 PTHR44340:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 10 DNAJ HOMOLOG SUBFAMILY C MEMBER 10 chaperone#PC00072 HUMAN|HGNC=17279|UniProtKB=Q99935 Q99935 OPRPN PTHR14179:SF8 SMR1-RELATED OPIORPHIN PREPROPEPTIDE peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase inhibitor activity#GO:0004866;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;system process#GO:0003008;biological regulation#GO:0065007;sensory perception of pain#GO:0019233;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;regulation of system process#GO:0044057 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=2218|UniProtKB=Q14055 Q14055 COL9A2 PTHR24023:SF906 COLLAGEN ALPHA COLLAGEN ALPHA-2(IX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;basement membrane#GO:0005604;extracellular region#GO:0005576;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;supramolecular polymer#GO:0099081 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=5115|UniProtKB=P17483 P17483 HOXB4 PTHR45771:SF3 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-B4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=32472|UniProtKB=Q49A33 Q49A33 ZNF876P PTHR24384:SF110 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 85-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=1806|UniProtKB=Q99626 Q99626 CDX2 PTHR24332:SF27 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=16695|UniProtKB=P51572 P51572 BCAP31 PTHR12701:SF15 BCR-ASSOCIATED PROTEIN, BAP B-CELL RECEPTOR-ASSOCIATED PROTEIN 31 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=6910|UniProtKB=O95460 O95460 MATN4 PTHR24020:SF14 COLLAGEN ALPHA MATRILIN-4 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=15995|UniProtKB=Q86WD7 Q86WD7 SERPINA9 PTHR11461:SF40 SERINE PROTEASE INHIBITOR, SERPIN SERPIN A9 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=18380|UniProtKB=Q7L1Q6 Q7L1Q6 BZW1 PTHR14208:SF0 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=11536|UniProtKB=Q6P1X5 Q6P1X5 TAF2 PTHR15137:SF9 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;RNA polymerase II general transcription initiation factor activity#GO:0016251 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=8823|UniProtKB=P16284 P16284 PECAM1 PTHR11481:SF5 IMMUNOGLOBULIN FC RECEPTOR PLATELET ENDOTHELIAL CELL ADHESION MOLECULE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological adhesion#GO:0022610;biological regulation#GO:0065007;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=12644|UniProtKB=Q15836 Q15836 VAMP3 PTHR45701:SF6 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 3 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;syntaxin-1 binding#GO:0017075;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular#GO:0005622;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 HUMAN|HGNC=10878|UniProtKB=Q9Y336 Q9Y336 SIGLEC9 PTHR12035:SF117 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 9 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=14728|UniProtKB=Q8NGD2 Q8NGD2 OR4K2 PTHR48002:SF104 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K2 transmembrane signal receptor#PC00197 HUMAN|HGNC=24078|UniProtKB=O43827 O43827 ANGPTL7 PTHR19143:SF40 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 7 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=11694|UniProtKB=P51808 P51808 DYNLT3 PTHR21255:SF20 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE 3 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=29215|UniProtKB=Q9ULL8 Q9ULL8 SHROOM4 PTHR15012:SF35 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cortical cytoskeleton#GO:0030863;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;apical junction complex#GO:0043296 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=25971|UniProtKB=Q9H6Y2 Q9H6Y2 WDR55 PTHR44019:SF20 WD REPEAT-CONTAINING PROTEIN 55 WD REPEAT-CONTAINING PROTEIN 55 HUMAN|HGNC=6570|UniProtKB=O00182 O00182 LGALS9 PTHR11346:SF170 GALECTIN GALECTIN-9 carbohydrate derivative binding#GO:0097367;carbohydrate binding#GO:0030246;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of biological process#GO:0048519;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;gene expression#GO:0010467;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;cytokine production#GO:0001816;leukocyte cell-cell adhesion#GO:0007159;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;negative regulation of multicellular organismal process#GO:0051241;T cell proliferation#GO:0042098;positive regulation of metabolic process#GO:0009893;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;negative regulation of cell population proliferation#GO:0008285;regulation of gene expression#GO:0010468;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;lymphocyte activation#GO:0046649;regulation of cell population proliferation#GO:0042127;negative regulation of T cell activation#GO:0050868;macromolecule metabolic process#GO:0043170;cell-cell adhesion#GO:0098609;negative regulation of metabolic process#GO:0009892;lymphocyte proliferation#GO:0046651;cell adhesion#GO:0007155;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;regulation of T cell proliferation#GO:0042129;negative regulation of cell adhesion#GO:0007162;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;regulation of macromolecule metabolic process#GO:0060255;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;multicellular organismal process#GO:0032501;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250;regulation of leukocyte proliferation#GO:0070663;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 extracellular matrix protein#PC00102 HUMAN|HGNC=5141|UniProtKB=P00738 P00738 HP PTHR24255:SF30 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED HAPTOGLOBIN serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;inflammatory response#GO:0006954;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;defense response#GO:0006952;protein metabolic process#GO:0019538;positive regulation of cell death#GO:0010942;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=29232|UniProtKB=Q460N5 Q460N5 PARP14 PTHR14453:SF89 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription corepressor activity#GO:0003714 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;gene expression#GO:0010467;negative regulation of metabolic process#GO:0009892;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7015|UniProtKB=Q16819 Q16819 MEP1A PTHR10127:SF824 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING MEPRIN A SUBUNIT ALPHA hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153 HUMAN|HGNC=3423|UniProtKB=P11678 P11678 EPX PTHR11475:SF132 OXIDASE/PEROXIDASE EOSINOPHIL PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180 HUMAN|HGNC=14882|UniProtKB=Q9NQ79 Q9NQ79 CRTAC1 PTHR16026:SF0 CARTILAGE ACIDIC PROTEIN 1 CARTILAGE ACIDIC PROTEIN 1 HUMAN|HGNC=3343|UniProtKB=P19622 P19622 EN2 PTHR24341:SF5 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN ENGRAILED-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 HUMAN|HGNC=11941|UniProtKB=O95271 O95271 TNKS PTHR24180:SF3 CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED POLY [ADP-RIBOSE] POLYMERASE TANKYRASE-1 transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;telomere capping#GO:0016233;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule localization#GO:0033036;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;telomere organization#GO:0032200;cellular protein localization#GO:0034613;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of Wnt signaling pathway#GO:0030177;telomere maintenance#GO:0000723;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;anatomical structure homeostasis#GO:0060249;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase inhibitor#PC00139 HUMAN|HGNC=5033|UniProtKB=P22626 P22626 HNRNPA2B1 PTHR48026:SF13 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2/B1 HUMAN|HGNC=5346|UniProtKB=P32942 P32942 ICAM3 PTHR13771:SF17 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|Gene=YK041_HUMAN|UniProtKB=Q3C1V9 Q3C1V9 - PTHR24173:SF72 FAMILY NOT NAMED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16 HUMAN|HGNC=16239|UniProtKB=Q9H4K7 Q9H4K7 MTG2 PTHR11702:SF31 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2 HUMAN|HGNC=2695|UniProtKB=Q16643 Q16643 DBN1 PTHR10829:SF1 CORTACTIN AND DREBRIN DREBRIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;dendrite development#GO:0016358;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;dendritic spine organization#GO:0097061;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;protein-containing complex subunit organization#GO:0043933;positive regulation of growth#GO:0045927;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular protein-containing complex assembly#GO:0034622;neuron projection extension#GO:1990138;regulation of multicellular organismal process#GO:0051239;regulation of dendritic spine development#GO:0060998;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;synapse organization#GO:0050808;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;regulation of synapse structure or activity#GO:0050803;positive regulation of neuron projection development#GO:0010976;positive regulation of cell growth#GO:0030307;positive regulation of multicellular organismal process#GO:0051240;regulation of dendrite morphogenesis#GO:0048814;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;positive regulation of cell projection organization#GO:0031346;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;growth#GO:0040007;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;system development#GO:0048731;regulation of protein-containing complex assembly#GO:0043254;axon extension#GO:0048675;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;neuron differentiation#GO:0030182;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of protein polymerization#GO:0032271;cell part morphogenesis#GO:0032990;regulation of cell growth#GO:0001558;regulation of anatomical structure size#GO:0090066;positive regulation of neuron differentiation#GO:0045666;developmental cell growth#GO:0048588;developmental growth involved in morphogenesis#GO:0060560;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;developmental growth#GO:0048589;regulation of actin filament length#GO:0030832;multicellular organism development#GO:0007275;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;cell growth#GO:0016049;dendrite morphogenesis#GO:0048813;positive regulation of developmental process#GO:0051094;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of supramolecular fiber organization#GO:1902903;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cortical actin cytoskeleton#GO:0030864;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;cell cortex#GO:0005938;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;neuron projection#GO:0043005;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 non-motor actin binding protein#PC00165 HUMAN|HGNC=1053|UniProtKB=Q9UBW5 Q9UBW5 BIN2 PTHR46514:SF1 AMPHIPHYSIN BRIDGING INTEGRATOR 2 lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;phagocytosis#GO:0006909;plasma membrane organization#GO:0007009;transport#GO:0006810;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=26531|UniProtKB=Q96M89 Q96M89 CCDC138 PTHR34523:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 138 COILED-COIL DOMAIN-CONTAINING PROTEIN 138 HUMAN|HGNC=28641|UniProtKB=Q86UA6 Q86UA6 RPAIN PTHR31742:SF1 RPA-INTERACTING PROTEIN RPAIN RPA-INTERACTING PROTEIN cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2040|UniProtKB=Q8N6F1 Q8N6F1 CLDN19 PTHR12002:SF27 CLAUDIN CLAUDIN-19 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=16696|UniProtKB=Q13573 Q13573 SNW1 PTHR12096:SF0 NUCLEAR PROTEIN SKIP-RELATED SNW DOMAIN-CONTAINING PROTEIN 1 RNA splicing factor#PC00148 HUMAN|HGNC=24179|UniProtKB=Q9C073 Q9C073 FAM117A PTHR14972:SF7 AGAP011572-PA PROTEIN FAM117A HUMAN|HGNC=29918|UniProtKB=Q9BU61 Q9BU61 NDUFAF3 PTHR21192:SF2 NUCLEAR PROTEIN E3-3 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3 HUMAN|HGNC=26720|UniProtKB=Q6AZW8 Q6AZW8 ZNF660 PTHR24390:SF175 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 660 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=37173|UniProtKB=Q6ZRP0 Q6ZRP0 PRR23C PTHR31813:SF6 PROLINE-RICH PROTEIN 23B PROLINE-RICH PROTEIN 23C HUMAN|HGNC=18096|UniProtKB=Q30KQ5 Q30KQ5 DEFB115 PTHR15001:SF9 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 115 antimicrobial response protein#PC00051 HUMAN|HGNC=23251|UniProtKB=Q6E213 Q6E213 AWAT2 PTHR12317:SF12 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYL-COA WAX ALCOHOL ACYLTRANSFERASE 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=15979|UniProtKB=Q9H3D4 Q9H3D4 TP63 PTHR11447:SF8 CELLULAR TUMOR ANTIGEN P53 TUMOR PROTEIN 63 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 P53-like transcription factor#PC00253 p53 pathway feedback loops 2#P04398>p53#P04668;p53 pathway by glucose deprivation#P04397>p53#P04640;P53 pathway feedback loops 1#P04392>p73DeltaN#P04537;p53 pathway#P00059>p53#P01485;P53 pathway feedback loops 1#P04392>p53#P04539;Huntington disease#P00029>p53#P00797;P53 pathway feedback loops 1#P04392>p73DeltaN#G04685;p53 pathway#P00059>p53#G04702 HUMAN|HGNC=1491|UniProtKB=P47756 P47756 CAPZB PTHR10619:SF0 F-ACTIN-CAPPING PROTEIN SUBUNIT BETA F-ACTIN-CAPPING PROTEIN SUBUNIT BETA cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;protein depolymerization#GO:0051261;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;anatomical structure development#GO:0048856;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=23749|UniProtKB=Q8N5B7 Q8N5B7 CERS5 PTHR12560:SF8 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 5 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|Gene=GNN|UniProtKB=Q6P2S7 Q6P2S7 TTC41P PTHR19871:SF31 BETA TRANSDUCIN-RELATED PROTEIN TETRATRICOPEPTIDE REPEAT PROTEIN 41-RELATED HUMAN|HGNC=4840|UniProtKB=P08631 P08631 HCK PTHR24418:SF245 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE HCK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell population proliferation#GO:0008283;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;innate immune response#GO:0045087;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;peptidyl-tyrosine modification#GO:0018212;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 Parkinson disease#P00049>Src kinase#P01230 HUMAN|HGNC=6477|UniProtKB=Q6GTX8 Q6GTX8 LAIR1 PTHR11738:SF154 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR 1 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=3395|UniProtKB=P54760 P54760 EPHB4 PTHR24416:SF296 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-B RECEPTOR 4 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=11102|UniProtKB=Q9NZC9 Q9NZC9 SMARCAL1 PTHR45766:SF3 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=33584|UniProtKB=A1A5D9 A1A5D9 BICDL2 PTHR32123:SF11 BICD FAMILY-LIKE CARGO ADAPTER BICD FAMILY-LIKE CARGO ADAPTER 2 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=20477|UniProtKB=Q8TCV5 Q8TCV5 WFDC5 PTHR19441:SF39 WHEY ACDIC PROTEIN WAP WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 5 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antibacterial humoral response#GO:0019731;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=13022|UniProtKB=Q9UJW7 Q9UJW7 ZNF229 PTHR24376:SF103 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 229 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7609|UniProtKB=Q13459 Q13459 MYO9B PTHR46184:SF2 UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN UNCONVENTIONAL MYOSIN-IXB Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=11952|UniProtKB=Q05952 Q05952 TNP2 PTHR17488:SF0 NUCLEAR TRANSITION PROTEIN 2 NUCLEAR TRANSITION PROTEIN 2 cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 male gamete generation#GO:0048232;fertilization#GO:0009566;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;reproduction#GO:0000003;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;acrosome reaction#GO:0007340;multicellular organismal reproductive process#GO:0048609 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=30652|UniProtKB=Q8WXE9 Q8WXE9 STON2 PTHR10529:SF345 AP COMPLEX SUBUNIT MU STONIN-2 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;clathrin binding#GO:0030276;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;regulation of endocytosis#GO:0030100;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;transport#GO:0006810;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;plasma membrane protein complex#GO:0098797;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;plasma membrane region#GO:0098590;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=29027|UniProtKB=O43149 O43149 ZZEF1 PTHR22772:SF4 NOVEL ZZ TYPE ZINC FINGER DOMAIN CONTAINING PROTEIN ZINC FINGER ZZ-TYPE AND EF-HAND DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=15634|UniProtKB=Q9BXR5 Q9BXR5 TLR10 PTHR24365:SF23 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 10 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;pattern recognition receptor signaling pathway#GO:0002221;cellular process#GO:0009987;defense response#GO:0006952;signaling#GO:0023052;inflammatory response#GO:0006954 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Toll receptor signaling pathway#P00054>TLR#P01346 HUMAN|HGNC=9089|UniProtKB=O43660 O43660 PLRG1 PTHR19923:SF0 WD40 REPEAT PROTEINPRL1/PRL2-RELATED PLEIOTROPIC REGULATOR 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974 HUMAN|HGNC=8378|UniProtKB=Q96RA2 Q96RA2 OR7D2 PTHR48001:SF107 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7D2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=28932|UniProtKB=Q14CN4 Q14CN4 KRT72 PTHR45616:SF2 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 72 HUMAN|HGNC=12191|UniProtKB=A0A087WV62 A0A087WV62 TRBV16 PTHR23268:SF24 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 16 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=19236|UniProtKB=Q96CS7 Q96CS7 PLEKHB2 PTHR14309:SF8 EXPRESSED PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY B MEMBER 2 regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;cellular process#GO:0009987 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=6299|UniProtKB=Q9NR82 Q9NR82 KCNQ5 PTHR11537:SF128 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 5 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;calmodulin binding#GO:0005516;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=12984|UniProtKB=O15535 O15535 ZSCAN9 PTHR23226:SF15 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 9 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26664|UniProtKB=Q8N841 Q8N841 TTLL6 PTHR12241:SF96 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL6 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=11986|UniProtKB=P11387 P11387 TOP1 PTHR10290:SF5 DNA TOPOISOMERASE I DNA TOPOISOMERASE 1 nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853 cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;chromatin remodeling#GO:0006338;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA topoisomerase#PC00017 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 HUMAN|HGNC=10433|UniProtKB=O75676 O75676 RPS6KA4 PTHR24351:SF41 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 p38 MAPK pathway#P05918>MSK2#P06039;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 HUMAN|HGNC=20298|UniProtKB=Q8IXQ4 Q8IXQ4 GPALPP1 PTHR46370:SF1 GPALPP MOTIFS-CONTAINING PROTEIN 1 GPALPP MOTIFS-CONTAINING PROTEIN 1 HUMAN|HGNC=14931|UniProtKB=Q9NTG7 Q9NTG7 SIRT3 PTHR48252:SF39 HISTONE DEACETYLASE 2-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL HUMAN|HGNC=14350|UniProtKB=Q8IVW6 Q8IVW6 ARID3B PTHR15348:SF3 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3B nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=30372|UniProtKB=Q2TBA0 Q2TBA0 KLHL40 PTHR24412:SF22 KELCH PROTEIN KELCH-LIKE PROTEIN 40 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20201|UniProtKB=Q9NWN3 Q9NWN3 FBXO34 PTHR16271:SF11 F-BOX ONLY PROTEIN 34/46 FAMILY MEMBER F-BOX ONLY PROTEIN 34 HUMAN|HGNC=9177|UniProtKB=Q07864 Q07864 POLE PTHR10670:SF0 DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A 3'-5'-exodeoxyribonuclease activity#GO:0008296;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;DNA-directed DNA polymerase activity#GO:0003887;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;exonuclease activity#GO:0004527;deoxyribonuclease activity#GO:0004536;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;exodeoxyribonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;3'-5' exonuclease activity#GO:0008408;DNA polymerase activity#GO:0034061;exodeoxyribonuclease activity, producing 5'-phosphomonoesters#GO:0016895 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;cellular nitrogen compound catabolic process#GO:0044270;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;base-excision repair#GO:0006284;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;aromatic compound catabolic process#GO:0019439;organelle organization#GO:0006996;DNA biosynthetic process#GO:0071897;organic cyclic compound catabolic process#GO:1901361;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;organelle fission#GO:0048285;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 HUMAN|HGNC=12722|UniProtKB=P62760 P62760 VSNL1 PTHR23055:SF101 CALCIUM BINDING PROTEINS VISININ-LIKE PROTEIN 1 HUMAN|HGNC=8668|UniProtKB=Q9Y5H9 Q9Y5H9 PCDHA2 PTHR24028:SF60 CADHERIN-87A PROTOCADHERIN ALPHA-2 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=44449|UniProtKB=D6R901 D6R901 USP17L21 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=23641|UniProtKB=Q9BS92 Q9BS92 NIPSNAP3B PTHR21017:SF18 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 3B cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12632|UniProtKB=Q93008 Q93008 USP9X PTHR24006:SF841 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE FAF-X-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell motility#GO:0048870;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;localization#GO:0051179;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;movement of cell or subcellular component#GO:0006928;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;cell migration#GO:0016477;protein metabolic process#GO:0019538;locomotion#GO:0040011;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|Ensembl=ENSG00000284779|UniProtKB=A0A2R8Y747 A0A2R8Y747 ENSG00000284779 PTHR11454:SF32 INSULIN/INSULIN GROWTH FACTOR INSULIN, ISOFORM 2 growth factor#PC00112 HUMAN|HGNC=29155|UniProtKB=Q9Y2G0 Q9Y2G0 EFR3B PTHR12444:SF4 UNCHARACTERIZED PROTEIN EFR3 HOMOLOG B protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=26001|UniProtKB=Q6ZP29 Q6ZP29 SLC66A1 PTHR16201:SF36 SEVEN TRANSMEMBRANE PROTEIN 1-RELATED LYSOSOMAL AMINO ACID TRANSPORTER 1 HOMOLOG intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=9476|UniProtKB=Q92743 Q92743 HTRA1 PTHR22939:SF13 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA1 serine protease#PC00203 HUMAN|HGNC=6831|UniProtKB=O00462 O00462 MANBA PTHR43730:SF1 BETA-MANNOSIDASE BETA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular macromolecule catabolic process#GO:0044265;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 protein modifying enzyme#PC00260 HUMAN|HGNC=10976|UniProtKB=Q9UI40 Q9UI40 SLC24A2 PTHR10846:SF41 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM/POTASSIUM/CALCIUM EXCHANGER 2 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;cation:cation antiporter activity#GO:0015491;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;solute:cation antiporter activity#GO:0015298;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of signaling#GO:0023051;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;chemical synaptic transmission#GO:0007268;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;ion homeostasis#GO:0050801;synaptic signaling#GO:0099536;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=15095|UniProtKB=Q8NGU2 Q8NGU2 OR9A4 PTHR24242:SF216 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 9A4 G-protein coupled receptor#PC00021 HUMAN|HGNC=23704|UniProtKB=Q5VTQ0 Q5VTQ0 TTC39B PTHR31859:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN 39B HUMAN|HGNC=6887|UniProtKB=P49137 P49137 MAPKAPK2 PTHR24349:SF63 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;kinase binding#GO:0019900;protein kinase activity#GO:0004672 signal transduction#GO:0007165;response to cytokine#GO:0034097;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;pattern recognition receptor signaling pathway#GO:0002221;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;inflammatory response#GO:0006954;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Ras Pathway#P04393>MAPKAP#P04564;Interleukin signaling pathway#P00036>MAPKAPK2#P00979;PDGF signaling pathway#P00047>MAPKAPK2#P01157;p38 MAPK pathway#P05918>MAPKAP-K2#P05920;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415;Angiogenesis#P00005>MAPKAPK2/3#P00244 HUMAN|HGNC=25815|UniProtKB=Q96MT8 Q96MT8 CEP63 PTHR18875:SF7 SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO CENTROSOMAL PROTEIN OF 63 KDA cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;epithelium development#GO:0060429;developmental process#GO:0032502;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;tissue development#GO:0009888;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 HUMAN|HGNC=23064|UniProtKB=Q9H4Y5 Q9H4Y5 GSTO2 PTHR43968:SF4 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA-2 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidation-reduction process#GO:0055114;metabolic process#GO:0008152 HUMAN|HGNC=5629|UniProtKB=P0DTE1 P0DTE1 IGHV3-38-3 PTHR23266:SF339 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-23-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=533|UniProtKB=P04083 P04083 ANXA1 PTHR10502:SF17 ANNEXIN ANNEXIN A1 hydrolase activity, acting on ester bonds#GO:0016788;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;catalytic activity#GO:0003824;cadherin binding#GO:0045296;metal ion binding#GO:0046872;enzyme inhibitor activity#GO:0004857;phospholipid binding#GO:0005543;enzyme regulator activity#GO:0030234;cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;hydrolase activity#GO:0016787;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;molecular function regulator#GO:0098772;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipase activity#GO:0004620;anion binding#GO:0043168 positive regulation of gene expression#GO:0010628;organelle membrane fusion#GO:0090174;nuclear division#GO:0000280;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;carboxylic acid biosynthetic process#GO:0046394;reproductive structure development#GO:0048608;tissue remodeling#GO:0048771;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cell migration#GO:0030334;tube morphogenesis#GO:0035239;anion transport#GO:0006820;positive regulation of mitotic cell cycle#GO:0045931;reproductive process#GO:0022414;regulation of G1/S transition of mitotic cell cycle#GO:2000045;leukocyte activation#GO:0045321;lymphocyte activation involved in immune response#GO:0002285;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;organic anion transport#GO:0015711;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;localization of cell#GO:0051674;cell communication#GO:0007154;cellular component organization#GO:0016043;negative regulation of transport#GO:0051051;endothelial cell migration#GO:0043542;cell cycle phase transition#GO:0044770;fatty acid derivative metabolic process#GO:1901568;regulation of cell cycle process#GO:0010564;cell activation#GO:0001775;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular response to chemical stress#GO:0062197;unsaturated fatty acid metabolic process#GO:0033559;angiogenesis#GO:0001525;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;type 2 immune response#GO:0042092;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of defense response#GO:0031347;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of lipid metabolic process#GO:0019216;protein localization to extracellular region#GO:0071692;apoptotic cell clearance#GO:0043277;taxis#GO:0042330;lipid metabolic process#GO:0006629;neurogenesis#GO:0022008;regulation of locomotion#GO:0040012;response to peptide hormone#GO:0043434;response to growth factor#GO:0070848;regulation of signaling#GO:0023051;hematopoietic or lymphoid organ development#GO:0048534;cell cycle process#GO:0022402;response to lipid#GO:0033993;growth#GO:0040007;positive regulation of T cell proliferation#GO:0042102;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;leukocyte cell-cell adhesion#GO:0007159;skin development#GO:0043588;cellular response to lipid#GO:0071396;negative regulation of multicellular organismal process#GO:0051241;organic substance transport#GO:0071702;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;positive regulation of programmed cell death#GO:0043068;response to radiation#GO:0009314;positive regulation of cell cycle process#GO:0090068;positive regulation of cell motility#GO:2000147;signal release#GO:0023061;cellular response to organic cyclic compound#GO:0071407;cell death#GO:0008219;regulation of immune system process#GO:0002682;immune effector process#GO:0002252;signaling#GO:0023052;cell-cell signaling#GO:0007267;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;carboxylic acid transport#GO:0046942;positive regulation of immune system process#GO:0002684;lymphocyte proliferation#GO:0046651;cell motility#GO:0048870;positive regulation of cellular biosynthetic process#GO:0031328;anatomical structure formation involved in morphogenesis#GO:0048646;negative regulation of cell activation#GO:0050866;regulation of T cell proliferation#GO:0042129;regulation of response to wounding#GO:1903034;membrane fusion#GO:0061025;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;positive regulation of cellular component organization#GO:0051130;regulation of lymphocyte proliferation#GO:0050670;regulation of cell death#GO:0010941;regulation of cell cycle#GO:0051726;negative regulation of lymphocyte activation#GO:0051250;actin cytoskeleton organization#GO:0030036;positive regulation of cell death#GO:0010942;negative regulation of catalytic activity#GO:0043086;long-chain fatty acid transport#GO:0015909;monocarboxylic acid transport#GO:0015718;membrane organization#GO:0061024;regulation of cell-cell adhesion#GO:0022407;positive regulation of cellular metabolic process#GO:0031325;icosanoid biosynthetic process#GO:0046456;gliogenesis#GO:0042063;regulation of T cell activation#GO:0050863;positive regulation of cellular component movement#GO:0051272;regulation of vesicle-mediated transport#GO:0060627;positive regulation of leukocyte activation#GO:0002696;DNA geometric change#GO:0032392;G1/S transition of mitotic cell cycle#GO:0000082;regulation of cell activation#GO:0050865;prostaglandin metabolic process#GO:0006693;leukocyte migration#GO:0050900;positive regulation of immune response#GO:0050778;hormone secretion#GO:0046879;establishment of localization#GO:0051234;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of secretion#GO:0051046;regulation of leukocyte cell-cell adhesion#GO:1903037;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;vasculature development#GO:0001944;leukocyte chemotaxis#GO:0030595;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;response to ionizing radiation#GO:0010212;circulatory system development#GO:0072359;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;positive regulation of locomotion#GO:0040017;tube development#GO:0035295;positive regulation of transport#GO:0051050;peptide transport#GO:0015833;positive regulation of T cell differentiation#GO:0045582;positive regulation of cellular process#GO:0048522;negative regulation of cell adhesion#GO:0007162;developmental process involved in reproduction#GO:0003006;response to wounding#GO:0009611;locomotion#GO:0040011;regulation of cellular metabolic process#GO:0031323;negative regulation of hydrolase activity#GO:0051346;response to organic cyclic compound#GO:0014070;epithelium development#GO:0060429;negative regulation of cell-cell adhesion#GO:0022408;developmental process#GO:0032502;transport#GO:0006810;wound healing#GO:0042060;regulation of angiogenesis#GO:0045765;peptide secretion#GO:0002790;regulation of cell differentiation#GO:0045595;response to estradiol#GO:0032355;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to endogenous stimulus#GO:0009719;granulocyte chemotaxis#GO:0071621;positive regulation of metabolic process#GO:0009893;peptide hormone secretion#GO:0030072;regulation of hormone secretion#GO:0046883;hemopoiesis#GO:0030097;regulation of gene expression#GO:0010468;regulation of lymphocyte activation#GO:0051249;regulation of cytokine production#GO:0001817;epidermal cell differentiation#GO:0009913;gland development#GO:0048732;regulation of response to external stimulus#GO:0032101;positive regulation of cell differentiation#GO:0045597;regulation of apoptotic process#GO:0042981;developmental growth#GO:0048589;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;epithelial cell differentiation#GO:0030855;organic substance biosynthetic process#GO:1901576;regulation of hormone levels#GO:0010817;positive regulation of developmental process#GO:0051094;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;cellular response to growth factor stimulus#GO:0071363;organelle organization#GO:0006996;organelle fission#GO:0048285;regulation of leukocyte proliferation#GO:0070663;cell migration#GO:0016477;positive regulation of cell-cell adhesion#GO:0022409;carboxylic acid metabolic process#GO:0019752;response to cytokine#GO:0034097;liver development#GO:0001889;organic acid transport#GO:0015849;gene expression#GO:0010467;regulation of localization#GO:0032879;response to oxidative stress#GO:0006979;positive regulation of cell cycle G1/S phase transition#GO:1902808;lipid biosynthetic process#GO:0008610;nervous system development#GO:0007399;positive regulation of lymphocyte activation#GO:0051251;mitotic cell cycle#GO:0000278;secretion#GO:0046903;sprouting angiogenesis#GO:0002040;cytoskeleton organization#GO:0007010;regulation of adaptive immune response#GO:0002819;regulation of lipid biosynthetic process#GO:0046890;hormone transport#GO:0009914;defense response#GO:0006952;regulation of cellular component movement#GO:0051270;organic acid biosynthetic process#GO:0016053;regulation of multicellular organismal process#GO:0051239;monocarboxylic acid biosynthetic process#GO:0072330;regulation of immune response#GO:0050776;icosanoid metabolic process#GO:0006690;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell adhesion#GO:0007155;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;negative regulation of leukocyte activation#GO:0002695;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;reproduction#GO:0000003;leukocyte differentiation#GO:0002521;small molecule biosynthetic process#GO:0044283;export from cell#GO:0140352;regulation of cell cycle G1/S phase transition#GO:1902806;small molecule metabolic process#GO:0044281;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of angiogenesis#GO:0045766;mitotic cell cycle phase transition#GO:0044772;regulation of anatomical structure morphogenesis#GO:0022603;biological adhesion#GO:0022610;regulation of phospholipase activity#GO:0010517;positive regulation of adaptive immune response#GO:0002821;cytokine production#GO:0001816;inflammatory response#GO:0006954;amide transport#GO:0042886;T cell proliferation#GO:0042098;regulation of biosynthetic process#GO:0009889;regulation of leukocyte migration#GO:0002685;unsaturated fatty acid biosynthetic process#GO:0006636;myeloid leukocyte migration#GO:0097529;mitotic nuclear division#GO:0140014;vesicle organization#GO:0016050;lipid localization#GO:0010876;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of wound healing#GO:0090303;regulation of cell population proliferation#GO:0042127;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cell chemotaxis#GO:0060326;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;regulation of inflammatory response#GO:0050727;fatty acid metabolic process#GO:0006631;lymphocyte differentiation#GO:0030098;response to hormone#GO:0009725;positive regulation of cell migration#GO:0030335;regulation of mononuclear cell proliferation#GO:0032944;cell surface receptor signaling pathway#GO:0007166;positive regulation of T cell activation#GO:0050870;cell cycle#GO:0007049;positive regulation of cell adhesion#GO:0045785;regulation of mitotic cell cycle#GO:0007346;negative regulation of molecular function#GO:0044092;reproductive system development#GO:0061458;actin cytoskeleton reorganization#GO:0031532;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;regulation of secretion by cell#GO:1903530;cell population proliferation#GO:0008283;lipid transport#GO:0006869;establishment of protein localization#GO:0045184;granulocyte migration#GO:0097530;epidermis development#GO:0008544;regulation of wound healing#GO:0061041;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;leukocyte proliferation#GO:0070661;regulation of vasculature development#GO:1901342;negative regulation of leukocyte cell-cell adhesion#GO:1903038;positive regulation of cytokine production#GO:0001819;positive regulation of immune effector process#GO:0002699;insulin secretion#GO:0030073;response to abiotic stimulus#GO:0009628;positive regulation of biological process#GO:0048518;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;alpha-beta T cell differentiation#GO:0046632;cellular developmental process#GO:0048869;oxoacid metabolic process#GO:0043436;response to inorganic substance#GO:0010035;blood vessel morphogenesis#GO:0048514;negative regulation of T cell activation#GO:0050868;immune system development#GO:0002520;cellular response to organic substance#GO:0071310;regulation of organelle organization#GO:0033043;response to organonitrogen compound#GO:0010243;organic acid metabolic process#GO:0006082;exocytic process#GO:0140029;T cell differentiation#GO:0030217;monocarboxylic acid metabolic process#GO:0032787;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;exocytosis#GO:0006887;leukocyte activation involved in immune response#GO:0002366;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;response to interleukin-1#GO:0070555;positive regulation of cell activation#GO:0050867;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;vesicle fusion#GO:0006906;macromolecule localization#GO:0033036;regulation of lipase activity#GO:0060191;positive regulation of organelle organization#GO:0010638;cell cycle G1/S phase transition#GO:0044843;cellular response to steroid hormone stimulus#GO:0071383;animal organ development#GO:0048513;mitotic cell cycle process#GO:1903047;urogenital system development#GO:0001655;cellular response to oxygen-containing compound#GO:1901701;regulation of hemopoiesis#GO:1903706;regulation of transport#GO:0051049;response to peptide#GO:1901652;positive regulation of leukocyte cell-cell adhesion#GO:1903039;DNA duplex unwinding#GO:0032508;cellular response to oxidative stress#GO:0034599;regulation of cell adhesion#GO:0030155;fatty acid biosynthetic process#GO:0006633;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of apoptotic process#GO:0043065;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;regulation of cell motility#GO:2000145;ion transport#GO:0006811;regulation of response to stress#GO:0080134;DNA conformation change#GO:0071103;response to external stimulus#GO:0009605;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;cellular lipid metabolic process#GO:0044255;response to steroid hormone#GO:0048545 cytoplasm#GO:0005737;intracellular#GO:0005622;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 calcium-binding protein#PC00060 HUMAN|HGNC=17550|UniProtKB=Q96MU8 Q96MU8 KREMEN1 PTHR24269:SF13 KREMEN PROTEIN KREMEN PROTEIN 1 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Kremen#P01463 HUMAN|HGNC=5789|UniProtKB=A0A087WW87 A0A087WW87 IGKV2-40 PTHR23267:SF381 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-40-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=5617|UniProtKB=A0A075B6Q5 A0A075B6Q5 IGHV3-64 PTHR23266:SF339 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-23-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=757|UniProtKB=Q12797 Q12797 ASPH PTHR12366:SF29 ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=25824|UniProtKB=Q6ZW31 Q6ZW31 SYDE1 PTHR46150:SF2 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN SYDE1 GTPase-activating protein#PC00257 HUMAN|HGNC=23845|UniProtKB=Q8IY92 Q8IY92 SLX4 PTHR21541:SF3 BTB POZ DOMAIN CONTAINING 12 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;endodeoxyribonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;deoxyribonuclease activity#GO:0004536 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;DNA double-strand break processing#GO:0000729;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;meiotic chromosome separation#GO:0051307;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=14492|UniProtKB=Q8IXM3 Q8IXM3 MRPL41 PTHR21338:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L41 39S RIBOSOMAL PROTEIN L41, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=9086|UniProtKB=P60201 P60201 PLP1 PTHR11683:SF11 MYELIN PROTEOLIPID MYELIN PROTEOLIPID PROTEIN structural molecule activity#GO:0005198 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;gliogenesis#GO:0042063;cellular component organization#GO:0016043;cellular process#GO:0009987;oligodendrocyte differentiation#GO:0048709;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;glial cell differentiation#GO:0010001;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;axon development#GO:0061564;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;generation of neurons#GO:0048699;myelination#GO:0042552 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 myelin protein#PC00161 HUMAN|HGNC=16192|UniProtKB=Q9BYT1 Q9BYT1 SLC17A9 PTHR11662:SF279 SOLUTE CARRIER FAMILY 17 SOLUTE CARRIER FAMILY 17 MEMBER 9 secondary carrier transporter#PC00258 HUMAN|HGNC=13110|UniProtKB=P15621 P15621 ZNF44 PTHR24379:SF98 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 44 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4393|UniProtKB=P11488 P11488 GNAT1 PTHR10218:SF67 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 Enkephalin release#P05913>G-Protein (i)#P05974;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Opioid proenkephalin pathway#P05915>G-protein#P05994;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gtalpha#P00760;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 HUMAN|HGNC=15833|UniProtKB=Q96KR7 Q96KR7 PHACTR3 PTHR12751:SF7 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 phosphatase modulator#PC00184 HUMAN|HGNC=12019|UniProtKB=Q15661 Q15661 TPSAB1 PTHR24256:SF521 TRYPTASE-RELATED TRYPTASE ALPHA/BETA-1-RELATED serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=4278|UniProtKB=P35212 P35212 GJA4 PTHR11984:SF54 CONNEXIN GAP JUNCTION ALPHA-4 PROTEIN gap junction#PC00105 HUMAN|HGNC=14480|UniProtKB=Q9NWU5 Q9NWU5 MRPL22 PTHR13501:SF8 CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED 39S RIBOSOMAL PROTEIN L22, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=33155|UniProtKB=Q2VPJ9 Q2VPJ9 LRRC75B PTHR14224:SF40 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 75B cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9888|UniProtKB=Q15291 Q15291 RBBP5 PTHR44040:SF1 RETINOBLASTOMA-BINDING PROTEIN 5 RETINOBLASTOMA-BINDING PROTEIN 5 HUMAN|HGNC=4028|UniProtKB=P59646 P59646 FXYD4 PTHR14132:SF10 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of sodium ion transport#GO:0002028;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;sodium ion transport#GO:0006814;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;sodium ion transmembrane transport#GO:0035725 primary active transporter#PC00068 HUMAN|HGNC=34524|UniProtKB=A6NFH5 A6NFH5 FABP12 PTHR11955:SF76 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN 12 HUMAN|HGNC=19280|UniProtKB=Q9H7H0 Q9H7H0 METTL17 PTHR21320:SF3 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL-RELATED chaperone#PC00072 HUMAN|HGNC=2606|UniProtKB=O15528 O15528 CYP27B1 PTHR24291:SF3 CYTOCHROME P450 FAMILY 4 25-HYDROXYVITAMIN D-1 ALPHA HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177 Vitamin D metabolism and pathway#P04396>1alpha-Hydroxylase#P04603;Vitamin D metabolism and pathway#P04396>25-Hydroxylase#P04601 HUMAN|HGNC=27375|UniProtKB=Q8IXL7 Q8IXL7 MSRB3 PTHR10173:SF56 METHIONINE SULFOXIDE REDUCTASE METHIONINE-R-SULFOXIDE REDUCTASE B3 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=35237|UniProtKB=P0DMP2 P0DMP2 SRGAP2B PTHR14166:SF6 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 2-RELATED Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048 regulation of cellular component movement#GO:0051270;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;localization of cell#GO:0051674;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of cell motility#GO:2000146;cell migration#GO:0016477;locomotion#GO:0040011;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=2638|UniProtKB=P20815 P20815 CYP3A5 PTHR24302:SF20 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A5 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;oxidative demethylation#GO:0070989;oxidation-reduction process#GO:0055114;demethylation#GO:0070988;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177 HUMAN|HGNC=16212|UniProtKB=Q9H1Q7 Q9H1Q7 PCED1A PTHR14469:SF3 SARCOMA ANTIGEN NY-SAR-23 PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1A HUMAN|HGNC=33736|UniProtKB=A5PLL1 A5PLL1 ANKRD34B PTHR24156:SF1 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 34B HUMAN|HGNC=4325|UniProtKB=O95838 O95838 GLP2R PTHR45620:SF23 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON-LIKE PEPTIDE 2 RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=28306|UniProtKB=Q8N945 Q8N945 PRELID2 PTHR11158:SF20 MSF1/PX19 RELATED PRELI DOMAIN-CONTAINING PROTEIN 2 binding#GO:0005488;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 HUMAN|HGNC=10780|UniProtKB=Q07955 Q07955 SRSF1 PTHR23147:SF44 SERINE/ARGININE RICH SPLICING FACTOR SERINE/ARGININE-RICH SPLICING FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=13112|UniProtKB=P24278 P24278 ZBTB25 PTHR24399:SF28 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 25 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=30667|UniProtKB=Q9UGT4 Q9UGT4 SUSD2 PTHR13802:SF52 MUCIN 4-RELATED SUSHI DOMAIN-CONTAINING PROTEIN 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=30306|UniProtKB=Q99623 Q99623 PHB2 PTHR23222:SF1 PROHIBITIN PROHIBITIN-2 HUMAN|HGNC=4396|UniProtKB=P62873 P62873 GNB1 PTHR19850:SF29 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(T) SUBUNIT BETA-1 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Wnt signaling pathway#P00057>GBeta#P01457;Nicotine pharmacodynamics pathway#P06587>GNB#P06591;PI3 kinase pathway#P00048>Gbetagamma#P01188;GABA-B receptor II signaling#P05731>Gbeta#P05755;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;CCKR signaling map#P06959>Gbeta/gamma#P07197;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753 HUMAN|HGNC=6804|UniProtKB=P43360 P43360 MAGEA6 PTHR11736:SF60 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 3-RELATED scaffold/adaptor protein#PC00226 HUMAN|Gene=YA043_HUMAN|UniProtKB=Q7L0L9 Q7L0L9 - PTHR24232:SF91 G-PROTEIN COUPLED RECEPTOR TRANSMEMBRANE PROTEIN LOC653160 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=12482|UniProtKB=P62253 P62253 UBE2G1 PTHR24067:SF3 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=14411|UniProtKB=Q9BQT8 Q9BQT8 SLC25A21 PTHR46356:SF1 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER secondary carrier transporter#PC00258 HUMAN|HGNC=30539|UniProtKB=Q8NEP3 Q8NEP3 DNAAF1 PTHR45973:SF19 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN ASSEMBLY FACTOR 1, AXONEMAL phosphatase modulator#PC00184 HUMAN|HGNC=18631|UniProtKB=Q9P1V8 Q9P1V8 SAMD15 PTHR46829:SF1 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15 HUMAN|HGNC=1121|UniProtKB=P35070 P35070 BTC PTHR10740:SF3 TRANSFORMING GROWTH FACTOR ALPHA PROBETACELLULIN regulation of protein modification process#GO:0031399;regulation of mitotic nuclear division#GO:0007088;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of organelle organization#GO:0033043;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell cycle process#GO:0090068;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of mitotic cell cycle#GO:0007346 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 HUMAN|HGNC=11580|UniProtKB=Q15814 Q15814 TBCC PTHR15139:SF0 TUBULIN FOLDING COFACTOR C TUBULIN-SPECIFIC CHAPERONE C cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein folding#GO:0006457;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=21906|UniProtKB=Q9NX63 Q9NX63 CHCHD3 PTHR21588:SF2 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6 MICOS COMPLEX SUBUNIT MIC19 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=28406|UniProtKB=A8MPX8 A8MPX8 PP2D1 PTHR13832:SF778 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=31837|UniProtKB=Q8N5X7 Q8N5X7 EIF4E3 PTHR11960:SF18 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;RNA cap binding#GO:0000339 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=32700|UniProtKB=Q8IW40 Q8IW40 CCDC103 PTHR28572:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 103 COILED-COIL DOMAIN-CONTAINING PROTEIN 103 microtubule-based protein transport#GO:0099118;specification of symmetry#GO:0009799;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;inner dynein arm assembly#GO:0036159;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;anatomical structure development#GO:0048856;axonemal dynein complex assembly#GO:0070286;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;developmental process#GO:0032502;transport#GO:0006810;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;determination of bilateral symmetry#GO:0009855;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;determination of left/right symmetry#GO:0007368;protein localization to organelle#GO:0033365;pattern specification process#GO:0007389;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 HUMAN|HGNC=15957|UniProtKB=Q8IUB2 Q8IUB2 WFDC3 PTHR19441:SF82 WHEY ACDIC PROTEIN WAP WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 3 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antibacterial humoral response#GO:0019731;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=7552|UniProtKB=Q13203 Q13203 MYBPH PTHR13817:SF49 TITIN MYOSIN-BINDING PROTEIN H-RELATED HUMAN|HGNC=12505|UniProtKB=P11441 P11441 UBL4A PTHR46555:SF1 UBIQUITIN-LIKE PROTEIN 4A UBIQUITIN-LIKE PROTEIN 4A HUMAN|HGNC=18001|UniProtKB=O96008 O96008 TOMM40 PTHR10802:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 HOMOLOG protein transmembrane transporter activity#GO:0008320;amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 primary active transporter#PC00068 HUMAN|HGNC=4119|UniProtKB=Q01415 Q01415 GALK2 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 carbohydrate kinase#PC00065 Fructose galactose metabolism#P02744>Galactokinase#P02960 HUMAN|HGNC=11124|UniProtKB=P55854 P55854 SUMO3 PTHR10562:SF79 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 3-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 p53 pathway#P00059>Sumo-1 ligase#P04635 HUMAN|Ensembl=ENSG00000270339|UniProtKB=A0A075B767 A0A075B767 PPIAL4H PTHR11071:SF466 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A-LIKE 4C-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=12303|UniProtKB=O75962 O75962 TRIO PTHR22826:SF104 RHO GUANINE EXCHANGE FACTOR-RELATED TRIPLE FUNCTIONAL DOMAIN PROTEIN guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=20366|UniProtKB=Q6UWI4 Q6UWI4 SHISA2 PTHR31395:SF0 SHISA PROTEIN SHISA-2 HOMOLOG scaffold/adaptor protein#PC00226 HUMAN|HGNC=4407|UniProtKB=P50150 P50150 GNG4 PTHR13809:SF21 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-4 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Dopamine receptor mediated signaling pathway#P05912>Ggamma#P05967;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 HUMAN|HGNC=28834|UniProtKB=Q3KPI0 Q3KPI0 CEACAM21 PTHR12080:SF104 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 21 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=5255|UniProtKB=Q58FG1 Q58FG1 HSP90AA4P PTHR11528:SF87 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-ALPHA-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of biological quality#GO:0065008;response to heat#GO:0009408;protein folding#GO:0006457;cellular response to heat#GO:0034605;biological regulation#GO:0065007;regulation of protein stability#GO:0031647;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;cellular process#GO:0009987;protein stabilization#GO:0050821 somatodendritic compartment#GO:0036477;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;cell surface#GO:0009986;cell body#GO:0044297;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 Hsp90 family chaperone#PC00028 HUMAN|HGNC=7974|UniProtKB=Q9Y5X4 Q9Y5X4 NR2E3 PTHR24083:SF4 NUCLEAR HORMONE RECEPTOR PHOTORECEPTOR-SPECIFIC NUCLEAR RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=17229|UniProtKB=Q9UL16 Q9UL16 CFAP45 PTHR15504:SF0 NASOPHARYNGEAL EPITHELIUM SPECIFIC PROTEIN 1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 45 HUMAN|HGNC=11038|UniProtKB=P53794 P53794 SLC5A3 PTHR11819:SF150 SOLUTE CARRIER FAMILY 5 SODIUM/MYO-INOSITOL COTRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;monovalent inorganic cation transmembrane transporter activity#GO:0015077;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;ion transmembrane transporter activity#GO:0015075;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=4683|UniProtKB=Q16661 Q16661 GUCA2B PTHR11318:SF4 GUANYLIN FAMILY MEMBER GUANYLATE CYCLASE ACTIVATOR 2B lyase activity#GO:0016829;molecular function regulator#GO:0098772;cyclase activity#GO:0009975;enzyme activator activity#GO:0008047;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095 HUMAN|HGNC=12590|UniProtKB=P07919 P07919 UQCRH PTHR15336:SF3 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respiratory chain complex III#GO:0005750;membrane-bounded organelle#GO:0043227 reductase#PC00198 HUMAN|HGNC=29270|UniProtKB=Q9P2E5 Q9P2E5 CHPF2 PTHR12369:SF14 CHONDROITIN SYNTHASE CHONDROITIN SULFATE GLUCURONYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;chondroitin sulfate metabolic process#GO:0030204;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;proteoglycan metabolic process#GO:0006029;chondroitin sulfate proteoglycan metabolic process#GO:0050654;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;glycosaminoglycan biosynthetic process#GO:0006024;small molecule metabolic process#GO:0044281 glycosyltransferase#PC00111 HUMAN|HGNC=957|UniProtKB=P80723 P80723 BASP1 PTHR23212:SF0 BRAIN ACID SOLUBLE PROTEIN 1 BRAIN ACID SOLUBLE PROTEIN 1 HUMAN|HGNC=16268|UniProtKB=Q8IY17 Q8IY17 PNPLA6 PTHR14226:SF26 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 6 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 esterase#PC00097 HUMAN|HGNC=22036|UniProtKB=Q8N8F7 Q8N8F7 LSMEM1 PTHR36475:SF1 LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 1 LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 1 HUMAN|HGNC=30917|UniProtKB=O95785 O95785 WIZ PTHR24396:SF22 ZINC FINGER PROTEIN PROTEIN WIZ cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26131|UniProtKB=Q6UX41 Q6UX41 BTNL8 PTHR24100:SF108 BUTYROPHILIN BUTYROPHILIN-LIKE PROTEIN 8 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=2934|UniProtKB=Q9Y5R6 Q9Y5R6 DMRT1 PTHR12322:SF70 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;reproductive process#GO:0022414;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;sex differentiation#GO:0007548;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;developmental process involved in reproduction#GO:0003006;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism reproduction#GO:0032504;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;multi-organism process#GO:0051704;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=9887|UniProtKB=Q09028 Q09028 RBBP4 PTHR22850:SF90 WD40 REPEAT FAMILY HISTONE-BINDING PROTEIN RBBP4 HUMAN|HGNC=25378|UniProtKB=Q8N612 Q8N612 FAM160A2 PTHR21705:SF4 RAI16 PROTEIN-RELATED FTS AND HOOK-INTERACTING PROTEIN HUMAN|HGNC=20247|UniProtKB=Q7L2J0 Q7L2J0 MEPCE PTHR12315:SF0 BICOID-INTERACTING PROTEIN RELATED 7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;methyltransferase activity#GO:0008168;heterocyclic compound binding#GO:1901363;snRNA binding#GO:0017069;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=20531|UniProtKB=P60328 P60328 KRTAP12-3 PTHR23262:SF148 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 12-3 HUMAN|HGNC=24961|UniProtKB=Q9BPY8 Q9BPY8 HOPX PTHR21408:SF1 HOMEODOMAIN-ONLY PROTEIN HOMEODOMAIN-ONLY PROTEIN cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8534|UniProtKB=P56373 P56373 P2RX3 PTHR10125:SF8 P2X PURINOCEPTOR P2X PURINOCEPTOR 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=16313|UniProtKB=P60985 P60985 KRTDAP PTHR36463:SF1 KERATINOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN KERATINOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN HUMAN|HGNC=19358|UniProtKB=Q9BV10 Q9BV10 ALG12 PTHR22760:SF1 GLYCOSYLTRANSFERASE DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=19718|UniProtKB=Q9HBX9 Q9HBX9 RXFP1 PTHR24372:SF68 GLYCOPROTEIN HORMONE RECEPTOR RELAXIN RECEPTOR 1 signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=14222|UniProtKB=Q9NQ69 Q9NQ69 LHX9 PTHR24208:SF95 LIM/HOMEOBOX PROTEIN LHX LIM/HOMEOBOX PROTEIN LHX9 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=24464|UniProtKB=Q8NCH0 Q8NCH0 CHST14 PTHR12137:SF33 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 14 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 HUMAN|HGNC=3085|UniProtKB=P54792 P54792 DVL1P1 PTHR10878:SF5 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1-RELATED protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Wnt signaling pathway#P00057>Dishevelled#P01447 HUMAN|HGNC=20445|UniProtKB=Q96DN6 Q96DN6 MBD6 PTHR16112:SF17 METHYL-CPG BINDING PROTEIN, DROSOPHILA METHYL-CPG-BINDING DOMAIN PROTEIN 6 chromatin binding#GO:0003682;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=1530|UniProtKB=Q9BPX6 Q9BPX6 MICU1 PTHR12294:SF1 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;mitochondrial calcium ion homeostasis#GO:0051560;mitochondrial transmembrane transport#GO:1990542;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;mitochondrial transport#GO:0006839;cellular chemical homeostasis#GO:0055082;mitochondrial calcium ion transmembrane transport#GO:0006851;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;ion channel complex#GO:0034702;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cation channel complex#GO:0034703;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 calmodulin-related#PC00061 HUMAN|HGNC=924|UniProtKB=P15291 P15291 B4GALT1 PTHR19300:SF5 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 1 glycosyltransferase#PC00111 HUMAN|HGNC=30074|UniProtKB=O14802 O14802 POLR3A PTHR19376:SF32 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=1675|UniProtKB=P09693 P09693 CD3G PTHR10570:SF8 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;lymphocyte activation#GO:0046649;immune system development#GO:0002520;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;hematopoietic or lymphoid organ development#GO:0048534;cell communication#GO:0007154;cellular process#GO:0009987;T cell differentiation#GO:0030217;cell activation#GO:0001775;regulation of biological process#GO:0050789;immune system process#GO:0002376;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;lymphocyte differentiation#GO:0030098;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;signaling#GO:0023052;leukocyte activation#GO:0045321 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 T cell activation#P00053>CD3 gamma#P01317;T cell activation#P00053>CD3 delta#P01326 HUMAN|HGNC=27033|UniProtKB=Q2M3V2 Q2M3V2 SOWAHA PTHR14491:SF2 UNCHARACTERIZED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHA HUMAN|HGNC=10570|UniProtKB=P48594 P48594 SERPINB4 PTHR11461:SF186 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B4 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=27270|UniProtKB=Q68BL7 Q68BL7 OLFML2A PTHR23192:SF29 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 2A structural protein#PC00211 HUMAN|HGNC=17171|UniProtKB=Q96JB6 Q96JB6 LOXL4 PTHR45817:SF5 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 4 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175 HUMAN|HGNC=12233|UniProtKB=A0A0A6YYG3 A0A0A6YYG3 TRBV6-8 PTHR23268:SF86 T-CELL RECEPTOR BETA CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=2948|UniProtKB=Q9P225 Q9P225 DNAH2 PTHR10676:SF183 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN 2, AXONEMAL pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 HUMAN|HGNC=29140|UniProtKB=Q9Y6X3 Q9Y6X3 MAU2 PTHR21394:SF0 UNCHARACTERIZED MAU2 CHROMATID COHESION FACTOR HOMOLOG nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 nuclear chromosome segregation#GO:0098813;mitotic sister chromatid cohesion#GO:0007064;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26444|UniProtKB=Q96N76 Q96N76 UROC1 PTHR12216:SF3 UROCANATE HYDRATASE UROCANATE HYDRATASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;small molecule catabolic process#GO:0044282;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid family metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281 hydratase#PC00120 HUMAN|HGNC=11479|UniProtKB=O43463 O43463 SUV39H1 PTHR46223:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H1 N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone methylation#GO:0016571;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;histone lysine methylation#GO:0034968;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=17591|UniProtKB=Q96B33 Q96B33 CLDN23 PTHR12002:SF3 CLAUDIN CLAUDIN-23 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=32268|UniProtKB=A6NIJ5 A6NIJ5 FAM90A20P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=14957|UniProtKB=Q14671 Q14671 PUM1 PTHR12537:SF1 RNA BINDING PROTEIN PUMILIO-RELATED PUMILIO HOMOLOG 1 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;gene silencing#GO:0016458;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;regulation of gene expression, epigenetic#GO:0040029;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;gene silencing by miRNA#GO:0035195;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of cellular catabolic process#GO:0031329;gene silencing by RNA#GO:0031047;regulation of RNA stability#GO:0043487;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;production of miRNAs involved in gene silencing by miRNA#GO:0035196;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;posttranscriptional gene silencing#GO:0016441;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=2511|UniProtKB=Q9UI47 Q9UI47 CTNNA3 PTHR18914:SF21 ALPHA CATENIN CATENIN ALPHA-3 non-motor actin binding protein#PC00165 Wnt signaling pathway#P00057>alpha-catenin#P01471;Cadherin signaling pathway#P00012>alpha-catenin#P00467 HUMAN|HGNC=14498|UniProtKB=P82675 P82675 MRPS5 PTHR13718:SF90 RIBOSOMAL S SUBUNIT 28S RIBOSOMAL PROTEIN S5, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 HUMAN|HGNC=23804|UniProtKB=Q9BPW5 Q9BPW5 RASL11B PTHR45704:SF6 RAS-LIKE FAMILY MEMBER 11 RAS-LIKE PROTEIN FAMILY MEMBER 11B HUMAN|HGNC=40047|UniProtKB=B5MCN3 B5MCN3 SEC14L6 PTHR23324:SF41 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 6-RELATED HUMAN|HGNC=27161|UniProtKB=Q6ICB4 Q6ICB4 PHETA2 PTHR22902:SF15 SESQUIPEDALIAN SESQUIPEDALIAN-2 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;endocytosis#GO:0006897;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;early endosome#GO:0005769;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=25199|UniProtKB=Q9BTV6 Q9BTV6 DPH7 PTHR46042:SF1 DIPHTHINE METHYLTRANSFERASE DIPHTHINE METHYLTRANSFERASE methyltransferase#PC00155 HUMAN|HGNC=34492|UniProtKB=A8MV24 A8MV24 C17orf98 PTHR34221:SF2 HYPOTHETICAL PROTEIN LOC691189 HYPOTHETICAL PROTEIN LOC691189 HUMAN|HGNC=2854|UniProtKB=Q86XP1 Q86XP1 DGKH PTHR11255:SF37 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 HUMAN|HGNC=25162|UniProtKB=Q96EH8 Q96EH8 NEURL3 PTHR12429:SF9 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL3 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;endocytosis#GO:0006897;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=26814|UniProtKB=Q5EBL4 Q5EBL4 RILPL1 PTHR21502:SF6 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN 1 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=11334|UniProtKB=P35346 P35346 SSTR5 PTHR24229:SF20 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 5 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;protein secretion#GO:0009306;regulation of localization#GO:0032879;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;hormone secretion#GO:0046879;cellular response to hormone stimulus#GO:0032870;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of secretion#GO:0051046;insulin secretion#GO:0030073;hormone transport#GO:0009914;regulation of protein localization#GO:0032880;regulation of peptide hormone secretion#GO:0090276;regulation of protein secretion#GO:0050708;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;peptide transport#GO:0015833;protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;regulation of cellular process#GO:0050794;protein transport#GO:0015031;G protein-coupled receptor signaling pathway#GO:0007186;protein localization to extracellular region#GO:0071692;regulation of establishment of protein localization#GO:0070201;export from cell#GO:0140352;regulation of peptide transport#GO:0090087;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;macromolecule localization#GO:0033036;cellular response to steroid hormone stimulus#GO:0071383;regulation of signaling#GO:0023051;transport#GO:0006810;regulation of insulin secretion#GO:0050796;response to lipid#GO:0033993;peptide secretion#GO:0002790;cellular response to lipid#GO:0071396;amide transport#GO:0042886;organic substance transport#GO:0071702;response to endogenous stimulus#GO:0009719;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;peptide hormone secretion#GO:0030072;neuropeptide signaling pathway#GO:0007218;regulation of hormone secretion#GO:0046883;cellular response to organic cyclic compound#GO:0071407;signal release#GO:0023061;regulation of protein transport#GO:0051223;signaling#GO:0023052;cell-cell signaling#GO:0007267;secretion by cell#GO:0032940;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;biological regulation#GO:0065007;response to steroid hormone#GO:0048545 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=6243|UniProtKB=Q9Y6H6 Q9Y6H6 KCNE3 PTHR15282:SF6 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;protein binding#GO:0005515;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 blood circulation#GO:0008015;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of metal ion transport#GO:0010959;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;action potential#GO:0001508;regulation of localization#GO:0032879;regulation of system process#GO:0044057;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;actin-mediated cell contraction#GO:0070252;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;actin filament-based process#GO:0030029;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;monovalent inorganic cation transport#GO:0015672;regulation of multicellular organismal process#GO:0051239;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of heart contraction#GO:0008016;ion transport#GO:0006811;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;regulation of membrane potential#GO:0042391;negative regulation of transport#GO:0051051;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;export from cell#GO:0140352;heart process#GO:0003015;muscle contraction#GO:0006936;negative regulation of molecular function#GO:0044092 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=35202|UniProtKB=C9J798 C9J798 RASA4B PTHR10194:SF4 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 4-RELATED GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646 HUMAN|HGNC=25244|UniProtKB=Q9UFE4 Q9UFE4 CCDC39 PTHR18962:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 39 COILED-COIL DOMAIN-CONTAINING PROTEIN 39 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;inner dynein arm assembly#GO:0036159;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;axonemal dynein complex assembly#GO:0070286;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=3062|UniProtKB=Q9NRD9 Q9NRD9 DUOX1 PTHR11972:SF75 NADPH OXIDASE DUAL OXIDASE 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;oxidoreductase complex#GO:1990204;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175 HUMAN|HGNC=376|UniProtKB=Q13023 Q13023 AKAP6 PTHR14514:SF2 PKA ANCHORING PROTEIN A-KINASE ANCHOR PROTEIN 6 HUMAN|HGNC=1103|UniProtKB=P25440 P25440 BRD2 PTHR22880:SF240 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS BROMODOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=11581|UniProtKB=Q9BTW9 Q9BTW9 TBCD PTHR12658:SF0 BETA-TUBULIN COFACTOR D TUBULIN-SPECIFIC CHAPERONE D GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein folding#GO:0006457;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987 chaperone#PC00072 HUMAN|HGNC=29603|UniProtKB=Q9UBD0 Q9UBD0 HSFX2 PTHR10015:SF282 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK TRANSCRIPTION FACTOR, X-LINKED winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=20588|UniProtKB=Q9UHG3 Q9UHG3 PCYOX1 PTHR15944:SF3 FARNESYLCYSTEINE LYASE PRENYLCYSTEINE OXIDASE 1 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 HUMAN|HGNC=25722|UniProtKB=Q8WTP8 Q8WTP8 AEN PTHR12801:SF57 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED APOPTOSIS-ENHANCING NUCLEASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 exoribonuclease#PC00099 HUMAN|HGNC=11869|UniProtKB=Q9UHN6 Q9UHN6 CEMIP2 PTHR15535:SF26 TRANSMEMBRANE PROTEIN 2-RELATED CELL SURFACE HYALURONIDASE HUMAN|HGNC=1799|UniProtKB=Q01850 Q01850 CDR2 PTHR19232:SF1 CENTROCORTIN FAMILY MEMBER CEREBELLAR DEGENERATION-RELATED PROTEIN 2 HUMAN|HGNC=14203|UniProtKB=Q8WXH2 Q8WXH2 JPH3 PTHR23085:SF7 GH28348P JUNCTOPHILIN-3 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;regulation of trans-synaptic signaling#GO:0099177;signaling#GO:0023052;cell-cell signaling#GO:0007267 intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=23271|UniProtKB=Q6MZT1 Q6MZT1 RGS7BP PTHR21029:SF12 R-SEVEN BINDING PROTEIN (R7BP) HOMOLOG REGULATOR OF G-PROTEIN SIGNALING 7-BINDING PROTEIN HUMAN|HGNC=21068|UniProtKB=Q7Z6P3 Q7Z6P3 RAB44 PTHR47977:SF12 LD21953P-RELATED RAS-RELATED PROTEIN RAB-44 HUMAN|HGNC=11474|UniProtKB=Q15526 Q15526 SURF1 PTHR23427:SF2 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 1 chaperone#PC00072 HUMAN|HGNC=478|UniProtKB=P19961 P19961 AMY2B PTHR43447:SF27 ALPHA-AMYLASE ALPHA-AMYLASE 2B-RELATED amylase#PC00048 HUMAN|HGNC=44395|UniProtKB=A1L162 A1L162 ERICH2 PTHR21520:SF2 UNCHARACTERIZED GLUTAMATE-RICH PROTEIN 2 HUMAN|HGNC=7449|UniProtKB=Q13613 Q13613 MTMR1 PTHR10807:SF40 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 1 hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=29208|UniProtKB=Q8TAM6 Q8TAM6 ERMN PTHR47137:SF1 ERMIN ERMIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cell projection organization#GO:0030030;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;morphogenesis of a branching structure#GO:0001763 supramolecular complex#GO:0099080;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;vesicle#GO:0031982;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;filopodium#GO:0030175;neuronal cell body#GO:0043025;extracellular region#GO:0005576;extracellular space#GO:0005615;cell cortex#GO:0005938;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axon#GO:0030424;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;neuron projection#GO:0043005;cell body#GO:0044297;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=24649|UniProtKB=Q9HBU6 Q9HBU6 ETNK1 PTHR22603:SF91 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE 1 kinase#PC00137 HUMAN|HGNC=21965|UniProtKB=Q92546 Q92546 RGP1 PTHR12507:SF3 REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED RAB6A-GEF COMPLEX PARTNER PROTEIN 2 Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=27049|UniProtKB=Q6IQ23 Q6IQ23 PLEKHA7 PTHR12752:SF4 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 7 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell junction organization#GO:0034330;biological adhesion#GO:0022610;protein-containing complex assembly#GO:0065003;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;apical junction complex#GO:0043296 HUMAN|HGNC=11818|UniProtKB=Q9Y5J9 Q9Y5J9 TIMM8B PTHR19338:SF10 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 13 HOMOLOG MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8 B HUMAN|HGNC=4710|UniProtKB=P20718 P20718 GZMH PTHR24271:SF83 KALLIKREIN-RELATED GRANZYME H intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 Apoptosis signaling pathway#P00006>Granzyme B#P00265 HUMAN|HGNC=23362|UniProtKB=Q96GX8 Q96GX8 C16orf74 PTHR37455:SF1 GENE, 27021-RELATED SIMILAR TO 1190005I06RIK PROTEIN HUMAN|HGNC=24144|UniProtKB=Q96A11 Q96A11 GAL3ST3 PTHR14647:SF81 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 3 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 HUMAN|HGNC=19907|UniProtKB=Q712K3 Q712K3 UBE2R2 PTHR24067:SF148 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 R2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=8618|UniProtKB=O43316 O43316 PAX4 PTHR45636:SF8 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=21288|UniProtKB=Q5T0Z8 Q5T0Z8 C6orf132 PTHR35077:SF2 SIMILAR TO AI661453 PROTEIN SIMILAR TO AI661453 PROTEIN HUMAN|HGNC=24663|UniProtKB=Q5R372 Q5R372 RABGAP1L PTHR22957:SF205 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN RAB GTPASE-ACTIVATING PROTEIN 1-LIKE GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=23915|UniProtKB=P0C7P1 P0C7P1 RBMY1D PTHR24012:SF685 RNA BINDING PROTEIN RNA-BINDING MOTIF PROTEIN, Y CHROMOSOME, FAMILY 1 MEMBER C-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=2766|UniProtKB=P60022 P60022 DEFB1 PTHR21388:SF9 BETA-DEFENSIN-RELATED BETA-DEFENSIN 1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;defense response to Gram-positive bacterium#GO:0050830;defense response to Gram-negative bacterium#GO:0050829;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;defense response to other organism#GO:0098542;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=21700|UniProtKB=Q6WBX8 Q6WBX8 RAD9B PTHR15237:SF2 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9B hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;intra-S DNA damage checkpoint#GO:0031573;regulation of biological process#GO:0050789;cellular response to abiotic stimulus#GO:0071214;cell cycle checkpoint#GO:0000075;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;response to abiotic stimulus#GO:0009628;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;response to ionizing radiation#GO:0010212;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;cellular metabolic process#GO:0044237;mitotic DNA damage checkpoint#GO:0044773;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;mitotic DNA integrity checkpoint#GO:0044774;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;DNA replication checkpoint#GO:0000076;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;cellular response to environmental stimulus#GO:0104004;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 exodeoxyribonuclease#PC00098 HUMAN|HGNC=10419|UniProtKB=P62273 P62273 RPS29 PTHR12010:SF2 40S RIBOSOMAL PROTEIN S29 40S RIBOSOMAL PROTEIN S29 cation binding#GO:0043169;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=49392|UniProtKB=A6NF36 A6NF36 CCDC182 PTHR37364:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 182 COILED-COIL DOMAIN-CONTAINING PROTEIN 182 HUMAN|HGNC=10602|UniProtKB=P51170 P51170 SCNN1G PTHR11690:SF19 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT GAMMA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=23375|UniProtKB=Q14C86 Q14C86 GAPVD1 PTHR23101:SF111 RAB GDP/GTP EXCHANGE FACTOR GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=1012|UniProtKB=P03999 P03999 OPN1SW PTHR24240:SF16 OPSIN SHORT-WAVE-SENSITIVE OPSIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to abiotic stimulus#GO:0071214;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=404|UniProtKB=P05091 P05091 ALDH2 PTHR11699:SF233 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=3385|UniProtKB=P21709 P21709 EPHA1 PTHR24416:SF28 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=20728|UniProtKB=Q9Y2E8 Q9Y2E8 SLC9A8 PTHR10110:SF86 SODIUM/HYDROGEN EXCHANGER SODIUM/HYDROGEN EXCHANGER 8 secondary carrier transporter#PC00258 HUMAN|HGNC=8582|UniProtKB=P00439 P00439 PAH PTHR11473:SF24 AROMATIC AMINO ACID HYDROXYLASE PHENYLALANINE-4-HYDROXYLASE HUMAN|HGNC=28314|UniProtKB=Q9BUK0 Q9BUK0 CHCHD7 PTHR46811:SF1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 HUMAN|HGNC=9287|UniProtKB=Q9UD71 Q9UD71 PPP1R1B PTHR15417:SF2 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1B regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phosphatase inhibitor#PC00183 Nicotine pharmacodynamics pathway#P06587>PPP1R1B#P06589;Dopamine receptor mediated signaling pathway#P05912>DARPP-32#P05950 HUMAN|HGNC=7850|UniProtKB=P22392 P22392 NME2 PTHR11349:SF57 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE B transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067 kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 HUMAN|HGNC=9717|UniProtKB=P28328 P28328 PEX2 PTHR48178:SF1 FAMILY NOT NAMED PEROXISOME BIOGENESIS FACTOR 2 lipid metabolic process#GO:0006629;very long-chain fatty acid metabolic process#GO:0000038;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;organelle organization#GO:0006996;cellular lipid metabolic process#GO:0044255;peroxisome organization#GO:0007031;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;integral component of organelle membrane#GO:0031301;microbody membrane#GO:0031903;RNA polymerase II, holoenzyme#GO:0016591;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;peroxisome#GO:0005777;microbody#GO:0042579;peroxisomal membrane#GO:0005778;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;membrane#GO:0016020;transcription elongation factor complex#GO:0008023;whole membrane#GO:0098805;cytoplasm#GO:0005737;RNA polymerase complex#GO:0030880;integral component of peroxisomal membrane#GO:0005779;protein-containing complex#GO:0032991;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=17970|UniProtKB=Q9BPZ3 Q9BPZ3 PAIP2 PTHR13154:SF2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2 translation regulator activity#GO:0045182 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=3354|UniProtKB=P13929 P13929 ENO3 PTHR11902:SF5 ENOLASE BETA-ENOLASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ATP generation from ADP#GO:0006757;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organelle fusion#GO:0048284;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;ADP metabolic process#GO:0046031;regulation of organelle organization#GO:0033043;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;vacuole fusion, non-autophagic#GO:0042144;regulation of cellular process#GO:0050794;glycolytic process#GO:0006096;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular#GO:0005622 lyase#PC00144 HUMAN|HGNC=27683|UniProtKB=Q6UX46 Q6UX46 ALKAL2 PTHR28676:SF2 ALK AND LTK LIGAND 2-RELATED ALK AND LTK LIGAND 2 protein tyrosine kinase activity#GO:0004713;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;signaling receptor binding#GO:0005102;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;ERK1 and ERK2 cascade#GO:0070371;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 HUMAN|HGNC=12108|UniProtKB=A0A0B4J241 A0A0B4J241 TRAV13-1 PTHR19433:SF64 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 13-1 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=14122|UniProtKB=Q96RY5 Q96RY5 CRAMP1 PTHR21677:SF1 CRAMPED PROTEIN PROTEIN CRAMPED-LIKE chromatin binding#GO:0003682;binding#GO:0005488 multicellular organismal process#GO:0032501;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=19262|UniProtKB=O95428 O95428 PAPLN PTHR13723:SF179 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE PAPILIN hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=21696|UniProtKB=Q9Y3Q8 Q9Y3Q8 TSC22D4 PTHR47610:SF1 TSC22 DOMAIN FAMILY PROTEIN 4 TSC22 DOMAIN FAMILY PROTEIN 4 response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;response to osmotic stress#GO:0006970 HUMAN|HGNC=25262|UniProtKB=Q5SNV9 Q5SNV9 C1orf167 PTHR38493:SF1 CHROMOSOME 1 OPEN READING FRAME 167 CHROMOSOME 1 OPEN READING FRAME 167 HUMAN|HGNC=6589|UniProtKB=Q86UP9 Q86UP9 LHFPL3 PTHR12489:SF13 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 3 PROTEIN multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of sound#GO:0007605;system process#GO:0003008 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=3974|UniProtKB=O95954 O95954 FTCD PTHR12234:SF0 FORMIMINOTRANSFERASE-CYCLODEAMINASE FORMIMIDOYLTRANSFERASE-CYCLODEAMINASE HUMAN|HGNC=273|UniProtKB=Q9Y6F1 Q9Y6F1 PARP3 PTHR10459:SF66 DNA LIGASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP3 transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 HUMAN|HGNC=37268|UniProtKB=A6NHZ5 A6NHZ5 LRRC14B PTHR14224:SF27 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14B cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=663|UniProtKB=P05089 P05089 ARG1 PTHR43782:SF2 ARGINASE ARGINASE-1 cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;arginine catabolic process#GO:0006527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 hydrolase#PC00121 HUMAN|HGNC=26548|UniProtKB=A2RTY3 A2RTY3 HEATR9 PTHR38323:SF1 PROTEIN HEATR9 PROTEIN HEATR9 HUMAN|HGNC=24172|UniProtKB=Q96BR9 Q96BR9 ZBTB8A PTHR24414:SF25 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 8A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=11615|UniProtKB=O75764 O75764 TCEA3 PTHR11477:SF4 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN TRANSCRIPTION ELONGATION FACTOR A PROTEIN 3 general transcription factor#PC00259 HUMAN|HGNC=35459|UniProtKB=A6NKD9 A6NKD9 CCDC85C PTHR13546:SF14 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85C cell junction#GO:0030054;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;apical junction complex#GO:0043296 HUMAN|HGNC=26115|UniProtKB=Q9H790 Q9H790 EXO5 PTHR14464:SF4 EXONUCLEASE V EXONUCLEASE V hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;exodeoxyribonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;exodeoxyribonuclease activity, producing 5'-phosphomonoesters#GO:0016895;deoxyribonuclease activity#GO:0004536 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|Ensembl=ENSG00000233087|UniProtKB=Q53S08 Q53S08 RAB6D PTHR24073:SF1089 DRAB5-RELATED RAS-RELATED PROTEIN RAB-6A-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=25471|UniProtKB=Q5MNZ9 Q5MNZ9 WIPI1 PTHR11227:SF23 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 1 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy of nucleus#GO:0044804;autophagy#GO:0006914 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;whole membrane#GO:0098805 HUMAN|HGNC=5261|UniProtKB=P10809 P10809 HSPD1 PTHR45633:SF17 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL protein binding#GO:0005515;chaperone binding#GO:0051087;binding#GO:0005488 positive regulation of gene expression#GO:0010628;cellular localization#GO:0051641;apoptotic mitochondrial changes#GO:0008637;regulation of cell-cell adhesion#GO:0022407;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of T cell activation#GO:0050863;establishment of protein localization#GO:0045184;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;regulation of leukocyte cell-cell adhesion#GO:1903037;apoptotic process#GO:0006915;positive regulation of cytokine production#GO:0001819;protein import#GO:0017038;positive regulation of biological process#GO:0048518;mitochondrial transmembrane transport#GO:1990542;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell adhesion#GO:0007155;protein localization to mitochondrion#GO:0070585;peptide transport#GO:0015833;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to topologically incorrect protein#GO:0035967;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;cell activation#GO:0001775;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;regulation of cellular process#GO:0050794;protein transport#GO:0015031;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;positive regulation of cell activation#GO:0050867;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;biological adhesion#GO:0022610;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;cytokine production#GO:0001816;leukocyte cell-cell adhesion#GO:0007159;amide transport#GO:0042886;organic substance transport#GO:0071702;positive regulation of metabolic process#GO:0009893;positive regulation of leukocyte cell-cell adhesion#GO:1903039;response to unfolded protein#GO:0006986;cell death#GO:0008219;regulation of immune system process#GO:0002682;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;regulation of gene expression#GO:0010468;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;localization#GO:0051179;mitochondrial transport#GO:0006839;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;protein folding#GO:0006457;establishment of protein localization to mitochondrion#GO:0072655;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;positive regulation of T cell activation#GO:0050870;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 membrane-enclosed lumen#GO:0031974;envelope#GO:0031975;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=2620|UniProtKB=P33260 P33260 CYP2C18 PTHR24300:SF358 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C18 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=1302|UniProtKB=P57060 P57060 RWDD2B PTHR15955:SF9 RWD DOMAIN CONTAINING PROTEIN 2 RWD DOMAIN-CONTAINING PROTEIN 2B ubiquitin-protein ligase#PC00234 HUMAN|HGNC=7450|UniProtKB=Q13614 Q13614 MTMR2 PTHR10807:SF42 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 2 hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=16842|UniProtKB=O14683 O14683 TP53I11 PTHR31584:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11 HUMAN|HGNC=3656|UniProtKB=Q9NZM1 Q9NZM1 MYOF PTHR12546:SF55 FER-1-LIKE MYOFERLIN endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;membrane fusion#GO:0061025;cellular process#GO:0009987;membrane organization#GO:0061024;plasma membrane organization#GO:0007009 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=33742|UniProtKB=Q5BKX8 Q5BKX8 CAVIN4 PTHR15240:SF4 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 4 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;plasma membrane raft#GO:0044853;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane region#GO:0098589;membrane microdomain#GO:0098857;whole membrane#GO:0098805;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=19659|UniProtKB=Q495N2 Q495N2 SLC36A3 PTHR22950:SF258 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 3 solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;proton transmembrane transporter activity#GO:0015078;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;proton transmembrane transport#GO:1902600;organic acid transport#GO:0015849;alanine transport#GO:0032328;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 amino acid transporter#PC00046 HUMAN|HGNC=48955|UniProtKB=C9J7I0 C9J7I0 UMAD1 PTHR36291:SF1 UBAP1-MVB12-ASSOCIATED (UMA)-DOMAIN CONTAINING PROTEIN 1 UBAP1-MVB12-ASSOCIATED (UMA)-DOMAIN CONTAINING PROTEIN 1 HUMAN|HGNC=13711|UniProtKB=Q8WVV4 Q8WVV4 POF1B PTHR22546:SF0 PREMATURE OVARIAN FAILURE, 1B PROTEIN POF1B HUMAN|HGNC=7203|UniProtKB=P41217 P41217 CD200 PTHR46841:SF3 OX-2 MEMBRANE GLYCOPROTEIN OX-2 MEMBRANE GLYCOPROTEIN HUMAN|HGNC=14493|UniProtKB=Q9Y6G3 Q9Y6G3 MRPL42 PTHR13450:SF4 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L42 39S RIBOSOMAL PROTEIN L42, MITOCHONDRIAL membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=19124|UniProtKB=Q6UN15 Q6UN15 FIP1L1 PTHR13484:SF9 FIP1-LIKE 1 PROTEIN PRE-MRNA 3'-END-PROCESSING FACTOR FIP1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 HUMAN|HGNC=3519|UniProtKB=Q99502 Q99502 EYA1 PTHR10190:SF11 EYES ABSENT EYES ABSENT HOMOLOG 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of apoptotic signaling pathway#GO:2001233;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;negative regulation of apoptotic signaling pathway#GO:2001234;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;protein dephosphorylation#GO:0006470;histone modification#GO:0016570;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;response to stress#GO:0006950;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;chromatin organization#GO:0006325;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of DNA repair#GO:0045739;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;protein modification process#GO:0036211;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of DNA repair#GO:0006282;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;negative regulation of programmed cell death#GO:0043069;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cell death#GO:0008219;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of cell death#GO:0010941;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=21895|UniProtKB=Q9H7X7 Q9H7X7 IFT22 PTHR24073:SF528 DRAB5-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 22 HOMOLOG GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=9835|UniProtKB=Q9Y5P3 Q9Y5P3 RAI2 PTHR23186:SF3 RETINOIC ACID-INDUCED PROTEIN 2 RETINOIC ACID-INDUCED PROTEIN 2 HUMAN|HGNC=25858|UniProtKB=Q8TCF1 Q8TCF1 ZFAND1 PTHR14677:SF37 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 1 RNA metabolism protein#PC00031 HUMAN|HGNC=2859|UniProtKB=Q15392 Q15392 DHCR24 PTHR10801:SF0 24-DEHYDROCHOLESTEROL REDUCTASE DELTA(24)-STEROL REDUCTASE reductase#PC00198 HUMAN|HGNC=30807|UniProtKB=Q6UXN2 Q6UXN2 TREML4 PTHR16423:SF9 TREM-LIKE TRANSCRIPT PROTEIN TREM-LIKE TRANSCRIPT 4 PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;pattern recognition receptor signaling pathway#GO:0002221;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|HGNC=26687|UniProtKB=Q8N9Z0 Q8N9Z0 ZNF610 PTHR24377:SF703 IP01015P-RELATED ZINC FINGER PROTEIN 610 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=14170|UniProtKB=Q96KJ4 Q96KJ4 MSLNL PTHR23412:SF15 STEREOCILIN RELATED MESOTHELIN-LIKE PROTEIN cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;biological adhesion#GO:0022610 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 HUMAN|HGNC=3270|UniProtKB=O75822 O75822 EIF3J PTHR21681:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=15451|UniProtKB=Q8NBJ4 Q8NBJ4 GOLM1 PTHR15896:SF8 GOLGI PHOSPHOPROTEIN 2/GP73-RELATED GOLGI MEMBRANE PROTEIN 1 HUMAN|HGNC=14677|UniProtKB=O75398 O75398 DEAF1 PTHR10237:SF13 DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=31990|UniProtKB=Q3BBV2 Q3BBV2 NBPF8 PTHR14199:SF35 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 10-RELATED HUMAN|HGNC=31012|UniProtKB=Q8WW24 Q8WW24 TEKT4 PTHR19960:SF12 TEKTIN MAFF-INTERACTING PROTEIN-RELATED microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cilium movement involved in cell motility#GO:0060294;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=15388|UniProtKB=Q8NGA5 Q8NGA5 OR10H4 PTHR24247:SF78 5-HYDROXYTRYPTAMINE RECEPTOR OLFACTORY RECEPTOR 10H4 cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=13047|UniProtKB=O75437 O75437 ZNF254 PTHR24377:SF912 IP01015P-RELATED ZINC FINGER PROTEIN 254-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8713|UniProtKB=Q9Y5F9 Q9Y5F9 PCDHGB6 PTHR24028:SF66 CADHERIN-87A PROTOCADHERIN GAMMA-B6 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=23301|UniProtKB=P30039 P30039 PBLD PTHR13774:SF17 PHENAZINE BIOSYNTHESIS PROTEIN PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN isomerase activity#GO:0016853;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=3818|UniProtKB=Q08050 Q08050 FOXM1 PTHR46878:SF1 FORKHEAD BOX PROTEIN M1 FORKHEAD BOX PROTEIN M1 HUMAN|HGNC=28971|UniProtKB=Q14159 Q14159 SPIDR PTHR34347:SF1 DNA REPAIR-SCAFFOLDING PROTEIN SPIDR DNA REPAIR-SCAFFOLDING PROTEIN DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular localization#GO:0051641;double-strand break repair#GO:0006302;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;regulation of localization#GO:0032879;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;protein localization to organelle#GO:0033365;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of establishment of protein localization#GO:0070201;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 HUMAN|HGNC=2890|UniProtKB=O60832 O60832 DKC1 PTHR23127:SF0 CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 H/ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;snRNA metabolic process#GO:0016073;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA 3'-end processing#GO:0031123;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 small nucleolar ribonucleoprotein complex#GO:0005732;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 centromere DNA-binding protein#PC00071 HUMAN|HGNC=17734|UniProtKB=Q96RJ0 Q96RJ0 TAAR1 PTHR24249:SF402 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 1 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|Ensembl=ENSG00000274707|UniProtKB=A0A0G2JPC4 A0A0G2JPC4 ENSG00000274707 PTHR11738:SF169 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 2DL5A-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=15789|UniProtKB=P53582 P53582 METAP1 PTHR43330:SF7 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1 metalloprotease#PC00153 HUMAN|HGNC=11757|UniProtKB=Q07654 Q07654 TFF3 PTHR13826:SF16 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 3 digestion#GO:0007586;multicellular organismal homeostasis#GO:0048871;tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;system process#GO:0003008;biological regulation#GO:0065007;homeostatic process#GO:0042592;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=19020|UniProtKB=Q96LD4 Q96LD4 TRIM47 PTHR25465:SF21 FAMILY NOT NAMED E3 UBIQUITIN-PROTEIN LIGASE TRIM47 HUMAN|HGNC=2253|UniProtKB=Q9BR76 Q9BR76 CORO1B PTHR10856:SF24 CORONIN CORONIN-1B cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 non-motor actin binding protein#PC00165 HUMAN|HGNC=29653|UniProtKB=Q7L3S4 Q7L3S4 ZNF771 PTHR24394:SF27 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 771 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=41912|UniProtKB=P0DH78 P0DH78 RNF224 PTHR47454:SF1 RING FINGER PROTEIN 224 RING FINGER PROTEIN 224 HUMAN|HGNC=16846|UniProtKB=Q15007 Q15007 WTAP PTHR15217:SF1 WILMS' TUMOR 1-ASSOCIATING PROTEIN PRE-MRNA-SPLICING REGULATOR WTAP cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA methylation#GO:0001510;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8101|UniProtKB=Q04671 Q04671 OCA2 PTHR43568:SF1 P PROTEIN P PROTEIN primary active transporter#PC00068 HUMAN|HGNC=20989|UniProtKB=Q96T66 Q96T66 NMNAT3 PTHR12039:SF7 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE/NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 3 adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 HUMAN|HGNC=12246|UniProtKB=A0A0B4J1U6 A0A0B4J1U6 TRBV9 PTHR23268:SF101 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 9 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=18386|UniProtKB=Q6UW10 Q6UW10 SFTA2 PTHR38500:SF1 SURFACTANT-ASSOCIATED PROTEIN 2 SURFACTANT-ASSOCIATED PROTEIN 2 surfactant#PC00212 HUMAN|HGNC=19331|UniProtKB=Q96EY8 Q96EY8 MMAB PTHR12213:SF0 CORRINOID ADENOSYLTRANSFERASE CORRINOID ADENOSYLTRANSFERASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 dehydrogenase#PC00092 HUMAN|HGNC=23061|UniProtKB=O95045 O95045 UPP2 PTHR43691:SF8 URIDINE PHOSPHORYLASE URIDINE PHOSPHORYLASE 2 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 HUMAN|HGNC=2151|UniProtKB=Q14028 Q14028 CNGB1 PTHR45638:SF16 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL BETA-1 cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;inorganic molecular entity transmembrane transporter activity#GO:0015318;nucleotide binding#GO:0000166;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;purine nucleotide binding#GO:0017076;gated channel activity#GO:0022836;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 ligand-gated ion channel#PC00141 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 HUMAN|HGNC=23987|UniProtKB=Q9UI09 Q9UI09 NDUFA12 PTHR12910:SF2 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.2 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 12 oxidoreductase#PC00176 HUMAN|HGNC=10442|UniProtKB=P46781 P46781 RPS9 PTHR11831:SF23 30S 40S RIBOSOMAL PROTEIN 40S RIBOSOMAL PROTEIN S9 structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;positive regulation of cellular protein metabolic process#GO:0032270;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=23481|UniProtKB=Q68J44 Q68J44 DUPD1 PTHR45682:SF6 AGAP008228-PA DUAL SPECIFICITY PHOSPHATASE DUPD1 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=23440|UniProtKB=Q8NCK3 Q8NCK3 ZNF485 PTHR24393:SF88 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1788|UniProtKB=P42772 P42772 CDKN2B PTHR24201:SF8 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR B p53 pathway#P00059>ARF#G01574 HUMAN|HGNC=16494|UniProtKB=Q9NRY7 Q9NRY7 PLSCR2 PTHR23248:SF29 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE 2 phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;plasma membrane organization#GO:0007009;ion transport#GO:0006811;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=25944|UniProtKB=Q9BUE0 Q9BUE0 MED18 PTHR13321:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 18 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=27229|UniProtKB=Q86W74 Q86W74 ANKRD46 PTHR24166:SF28 ROLLING PEBBLES, ISOFORM B ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 46 HUMAN|HGNC=9976|UniProtKB=O60858 O60858 TRIM13 PTHR24103:SF609 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM13 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macroautophagy#GO:0016236;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;proteolysis#GO:0006508;innate immune response#GO:0045087;proteasomal protein catabolic process#GO:0010498;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular metabolic process#GO:0044237;cell communication#GO:0007154;regulation of macroautophagy#GO:0016241;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;nucleobase-containing compound biosynthetic process#GO:0034654;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;autophagy#GO:0006914;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;signaling#GO:0023052;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of DNA-binding transcription factor activity#GO:0051091;immune system process#GO:0002376;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of nucleic acid-templated transcription#GO:1903506;cellular macromolecule catabolic process#GO:0044265;response to external biotic stimulus#GO:0043207;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;response to endoplasmic reticulum stress#GO:0034976;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;RNA biosynthetic process#GO:0032774;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of catabolic process#GO:0009896;aromatic compound biosynthetic process#GO:0019438;positive regulation of autophagy#GO:0010508;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;macromolecule modification#GO:0043412;positive regulation of cellular catabolic process#GO:0031331;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular macromolecule biosynthetic process#GO:0034645;regulation of DNA-binding transcription factor activity#GO:0051090;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of autophagy#GO:0010506;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;ubiquitin-dependent ERAD pathway#GO:0030433;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9537|UniProtKB=P20618 P20618 PSMB1 PTHR11599:SF59 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-1 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=966|UniProtKB=Q8NFJ9 Q8NFJ9 BBS1 PTHR20870:SF0 BARDET-BIEDL SYNDROME 1 PROTEIN BARDET-BIEDL SYNDROME 1 PROTEIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488 vesicle targeting, to, from or within Golgi#GO:0048199;non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;centriole#GO:0005814;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;cytoskeleton#GO:0005856;BBSome#GO:0034464;plasma membrane#GO:0005886 HUMAN|HGNC=29911|UniProtKB=Q13901 Q13901 C1D PTHR15341:SF6 SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;ribosome biogenesis#GO:0042254;regulation of gene expression#GO:0010468;maturation of 5.8S rRNA#GO:0000460;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;exosome (RNase complex)#GO:0000178 transcription cofactor#PC00217 HUMAN|HGNC=959|UniProtKB=Q07812 Q07812 BAX PTHR11256:SF42 BCL-2 RELATED APOPTOSIS REGULATOR BAX passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;protein homodimerization activity#GO:0042803;binding#GO:0005488;identical protein binding#GO:0042802;protein binding#GO:0005515;channel activity#GO:0015267;transporter activity#GO:0005215 mitochondrial fusion#GO:0008053;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;apoptotic mitochondrial changes#GO:0008637;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;apoptotic process#GO:0006915;cell death#GO:0008219;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organelle fusion#GO:0048284;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cellular response to stress#GO:0033554;positive regulation of cell death#GO:0010942 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 p53 pathway#P00059>BAX#G01581;Apoptosis signaling pathway#P00006>Bax#P00271;Huntington disease#P00029>Bax#G01533;CCKR signaling map#P06959>BAX#P07159 HUMAN|HGNC=6222|UniProtKB=P22459 P22459 KCNA4 PTHR11537:SF273 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=28558|UniProtKB=Q8N6Q1 Q8N6Q1 TMCO5A PTHR22422:SF7 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5B-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5A HUMAN|HGNC=6336|UniProtKB=P43632 P43632 KIR2DS4 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=26050|UniProtKB=Q9BUB7 Q9BUB7 TMEM70 PTHR13281:SF0 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 envelope#GO:0031975;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;integral component of membrane#GO:0016021;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|Ensembl=ENSG00000277263|UniProtKB=A0A0G2JMH6 A0A0G2JMH6 HLA-DRA PTHR19944:SF63 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN-RELATED major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 HUMAN|HGNC=23019|UniProtKB=Q15696 Q15696 ZRSR2 PTHR12620:SF38 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR 35 KDA SUBUNIT-RELATED PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 mRNA splicing#P00058>U2AF65#P01475 HUMAN|HGNC=10875|UniProtKB=O43699 O43699 SIGLEC6 PTHR12035:SF125 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 6 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=32058|UniProtKB=Q6WRX3 Q6WRX3 ZYG11A PTHR12904:SF20 FAMILY NOT NAMED PROTEIN ZYG-11 HOMOLOG A protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=1183|UniProtKB=Q9NQ90 Q9NQ90 ANO2 PTHR12308:SF20 NGEP-RELATED ANOCTAMIN-2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;inorganic anion transport#GO:0015698;anion transmembrane transport#GO:0098656 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=28819|UniProtKB=Q6ZV89 Q6ZV89 SH2D5 PTHR15832:SF3 SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG SH2 DOMAIN-CONTAINING PROTEIN 5 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;asymmetric synapse#GO:0032279 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18340|UniProtKB=Q8NEZ3 Q8NEZ3 WDR19 PTHR14920:SF2 OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN WD REPEAT-CONTAINING PROTEIN 19 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;intraciliary retrograde transport#GO:0035721;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=18712|UniProtKB=Q8N135 Q8N135 LGI4 PTHR24367:SF268 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 4 HUMAN|HGNC=1589|UniProtKB=P24864 P24864 CCNE1 PTHR10177:SF71 CYCLINS G1/S-SPECIFIC CYCLIN-E1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;G1/S transition of mitotic cell cycle#GO:0000082;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 Parkinson disease#P00049>Cyclin E#P01213;Cell cycle#P00013>CdkC#P00489;p53 pathway#P00059>Cyclin E#P04610;p53 pathway feedback loops 2#P04398>cyclin E#P04664;Cell cycle#P00013>Cyclin E#P00483 HUMAN|HGNC=19322|UniProtKB=Q8WY54 Q8WY54 PPM1E PTHR13832:SF535 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1E hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;protein phosphorylation#GO:0006468;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 protein phosphatase#PC00195 HUMAN|HGNC=28671|UniProtKB=Q86UE3 Q86UE3 ZNF546 PTHR24377:SF142 IP01015P-RELATED ZINC FINGER PROTEIN 546 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=865|UniProtKB=Q93050 Q93050 ATP6V0A1 PTHR11629:SF68 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A1 inorganic molecular entity transmembrane transporter activity#GO:0015318;binding#GO:0005488;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;enzyme binding#GO:0019899;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 pH reduction#GO:0045851;regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;regulation of cellular pH#GO:0030641;vacuolar acidification#GO:0007035 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ATP synthase#PC00002 HUMAN|HGNC=3583|UniProtKB=Q8NB91 Q8NB91 FANCB PTHR28450:SF1 FANCONI ANEMIA GROUP B PROTEIN FANCONI ANEMIA GROUP B PROTEIN DNA repair#GO:0006281;negative regulation of response to DNA damage stimulus#GO:2001021;regulation of double-strand break repair#GO:2000779;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of double-strand break repair via homologous recombination#GO:2000042;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;positive regulation of DNA repair#GO:0045739;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;negative regulation of DNA repair#GO:0045738;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of DNA repair#GO:0006282;regulation of double-strand break repair via homologous recombination#GO:0010569;positive regulation of response to stimulus#GO:0048584;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;negative regulation of double-strand break repair#GO:2000780;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of DNA recombination#GO:0000018;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;Fanconi anaemia nuclear complex#GO:0043240;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=13029|UniProtKB=Q9UJ78 Q9UJ78 ZMYM5 PTHR45736:SF7 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 5 zinc finger transcription factor#PC00244 HUMAN|HGNC=25638|UniProtKB=Q96EY4 Q96EY4 TMA16 PTHR13349:SF2 UNCHARACTERIZED TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=18329|UniProtKB=P62699 P62699 YPEL5 PTHR13848:SF58 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 5 HUMAN|HGNC=14370|UniProtKB=O95084 O95084 PRSS23 PTHR15462:SF10 SERINE PROTEASE SERINE PROTEASE 23 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=26623|UniProtKB=Q86X19 Q86X19 TMEM17 PTHR13531:SF14 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 17 vesicle targeting, to, from or within Golgi#GO:0048199;non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 HUMAN|HGNC=26043|UniProtKB=A1E959 A1E959 ODAM PTHR16237:SF3 ODONTOGENIC AMELOBLAST-ASSOCIATED PROTEIN ODONTOGENIC AMELOBLAST-ASSOCIATED PROTEIN HUMAN|HGNC=17940|UniProtKB=Q9P2K5 Q9P2K5 MYEF2 PTHR23003:SF15 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN MYELIN EXPRESSION FACTOR 2 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;response to oxidative stress#GO:0006979;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=15902|UniProtKB=Q8IXH8 Q8IXH8 CDH26 PTHR24027:SF78 CADHERIN-23 CADHERIN-LIKE PROTEIN 26 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 HUMAN|HGNC=4192|UniProtKB=P47871 P47871 GCGR PTHR45620:SF29 PDF RECEPTOR-LIKE PROTEIN-RELATED GLUCAGON RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=38689|UniProtKB=P0CJ88 P0CJ88 DUX4L5 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=16889|UniProtKB=O00487 O00487 PSMD14 PTHR10410:SF5 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 14 thiol-dependent ubiquitin-specific protease activity#GO:0004843;proteasome binding#GO:0070628;ubiquitinyl hydrolase activity#GO:0101005;metallopeptidase activity#GO:0008237;omega peptidase activity#GO:0008242;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein-containing complex binding#GO:0044877;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;proteasome complex#GO:0000502 translation initiation factor#PC00224 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 HUMAN|HGNC=11098|UniProtKB=P51531 P51531 SMARCA2 PTHR10799:SF541 SNF2/RAD54 HELICASE FAMILY GLOBAL TRANSCRIPTION ACTIVATOR SNF2L2-RELATED pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;transcription factor binding#GO:0008134;ATPase activity#GO:0016887 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=53|UniProtKB=Q92887 Q92887 ABCC2 PTHR24223:SF176 ATP-BINDING CASSETTE SUB-FAMILY C CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 1 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=25196|UniProtKB=Q96CK0 Q96CK0 ZNF653 PTHR46179:SF9 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 653 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6487|UniProtKB=P55268 P55268 LAMB2 PTHR10574:SF36 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-2 integrin binding#GO:0005178;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cell morphogenesis involved in differentiation#GO:0000904;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;substrate adhesion-dependent cell spreading#GO:0034446;localization of cell#GO:0051674;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;extracellular matrix organization#GO:0030198;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;cell differentiation#GO:0030154;extracellular structure organization#GO:0043062;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;cell migration#GO:0016477;locomotion#GO:0040011 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=13907|UniProtKB=Q8N100 Q8N100 ATOH7 PTHR19290:SF99 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED PROTEIN ATONAL HOMOLOG 7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=1686|UniProtKB=P19397 P19397 CD53 PTHR19282:SF39 TETRASPANIN LEUKOCYTE SURFACE ANTIGEN CD53 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=20302|UniProtKB=Q86VW1 Q86VW1 SLC22A16 PTHR24064:SF186 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 16 secondary carrier transporter#PC00258 HUMAN|HGNC=6126|UniProtKB=Q9Y4H2 Q9Y4H2 IRS2 PTHR10614:SF7 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 2 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 Interleukin signaling pathway#P00036>IRS1/2#P00980;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887;Gonadotropin-releasing hormone receptor pathway#P06664>IRS#P06759 HUMAN|HGNC=18932|UniProtKB=Q3LI66 Q3LI66 KRTAP6-2 PTHR31678:SF3 KERATIN-ASSOCIATED PROTEIN 6-3 KERATIN-ASSOCIATED PROTEIN 6-2 HUMAN|HGNC=26049|UniProtKB=Q9BU19 Q9BU19 ZNF692 PTHR24390:SF105 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 692 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=2852|UniProtKB=P52429 P52429 DGKE PTHR11255:SF80 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE EPSILON kinase#PC00137 HUMAN|HGNC=13785|UniProtKB=Q9HD23 Q9HD23 MRS2 PTHR13890:SF0 RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812 RNA splicing factor#PC00148 HUMAN|HGNC=756|UniProtKB=P45381 P45381 ASPA PTHR15162:SF9 ASPARTOACYLASE ASPARTOACYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=24238|UniProtKB=Q5VT06 Q5VT06 CEP350 PTHR13958:SF4 CENTROSOME-ASSOCIATED PROTEIN 350 CENTROSOME-ASSOCIATED PROTEIN 350 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=17662|UniProtKB=Q9UKA9 Q9UKA9 PTBP2 PTHR15592:SF16 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 2 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;RNA splicing#GO:0008380;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;biosynthetic process#GO:0009058;translation#GO:0006412;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;amide biosynthetic process#GO:0043604;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=30390|UniProtKB=Q7Z614 Q7Z614 SNX20 PTHR20939:SF1 SORTING NEXIN 20, 21 SORTING NEXIN-20 scaffold/adaptor protein#PC00226 HUMAN|HGNC=16496|UniProtKB=Q9UKU0 Q9UKU0 ACSL6 PTHR43272:SF54 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 6 ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;very long-chain fatty acid metabolic process#GO:0000038;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;organic acid metabolic process#GO:0006082;fatty acid derivative metabolic process#GO:1901568;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;fatty acid metabolic process#GO:0006631;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 ligase#PC00142 HUMAN|HGNC=24042|UniProtKB=Q9GZV5 Q9GZV5 WWTR1 PTHR17616:SF6 YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER WW DOMAIN-CONTAINING TRANSCRIPTION REGULATOR PROTEIN 1 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;hippo signaling#GO:0035329;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 HUMAN|HGNC=15505|UniProtKB=Q96N66 Q96N66 MBOAT7 PTHR13906:SF16 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 7 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;membrane#GO:0016020;mitochondria-associated endoplasmic reticulum membrane#GO:0044233 acetyltransferase#PC00038 HUMAN|HGNC=24678|UniProtKB=Q9C0B1 Q9C0B1 FTO PTHR31291:SF2 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO oxygenase#PC00177 HUMAN|HGNC=17342|UniProtKB=Q6RI45 Q6RI45 BRWD3 PTHR16266:SF25 WD REPEAT DOMAIN 9 BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 3 cellular aromatic compound metabolic process#GO:0006725;regulation of anatomical structure morphogenesis#GO:0022603;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;regulation of cell shape#GO:0008360;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;cytoskeleton organization#GO:0007010;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16091|UniProtKB=Q9NUB1 Q9NUB1 ACSS1 PTHR24095:SF110 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE 2-LIKE, MITOCHONDRIAL ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 HUMAN|HGNC=37701|UniProtKB=P0CG01 P0CG01 GKN3P PTHR16483:SF2 GASTROKINE 1 GASTROKINE-3 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell population proliferation#GO:0008283;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=18165|UniProtKB=Q9Y6J8 Q9Y6J8 STYXL1 PTHR46659:SF1 SERINE/THREONINE/TYROSINE-INTERACTING-LIKE PROTEIN 1 SERINE/THREONINE/TYROSINE-INTERACTING-LIKE PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;phosphatase inhibitor activity#GO:0019212;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096;protein phosphatase inhibitor activity#GO:0004864 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of programmed cell death#GO:0043068;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;negative regulation of organelle organization#GO:0010639;apoptotic process#GO:0006915;cell death#GO:0008219;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of organelle organization#GO:0033043;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of cell death#GO:0010942;regulation of intrinsic apoptotic signaling pathway#GO:2001242 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=26331|UniProtKB=Q96DL1 Q96DL1 NXPE2 PTHR16165:SF10 BRUSH BORDER-RELATED NXPE FAMILY MEMBER 2 HUMAN|HGNC=3438|UniProtKB=Q03468 Q03468 ERCC6 PTHR45629:SF7 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED HUMAN|HGNC=30908|UniProtKB=Q8WXG1 Q8WXG1 RSAD2 PTHR21339:SF0 RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 2 RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 2 4 iron, 4 sulfur cluster binding#GO:0051539;metal cluster binding#GO:0051540;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 HUMAN|HGNC=34439|UniProtKB=A8MZ97 A8MZ97 C2orf74 PTHR37882:SF1 HYPOTHETICAL PROTEIN LOC690352 HYPOTHETICAL PROTEIN LOC690352 HUMAN|HGNC=14366|UniProtKB=Q9H239 Q9H239 MMP28 PTHR10201:SF298 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-28 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=21297|UniProtKB=Q8TE67 Q8TE67 EPS8L3 PTHR12287:SF22 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8-LIKE PROTEIN 3 Rho guanyl-nucleotide exchange factor activity#GO:0005089;cytoskeletal protein binding#GO:0008092;Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;actin binding#GO:0003779;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cell projection organization#GO:0030030;positive regulation of cell projection organization#GO:0031346;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;regulation of cellular component organization#GO:0051128;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;positive regulation of cellular component biogenesis#GO:0044089;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;Rho protein signal transduction#GO:0007266;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;plasma membrane bounded cell projection assembly#GO:0120031;regulation of Ras protein signal transduction#GO:0046578 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=12128|UniProtKB=A0A0B4J244 A0A0B4J244 TRAV3 PTHR19367:SF8 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 3 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=4523|UniProtKB=Q9NYM4 Q9NYM4 GPR83 PTHR24238:SF65 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 83-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=6719|UniProtKB=Q16873 Q16873 LTC4S PTHR10250:SF4 MICROSOMAL GLUTATHIONE S-TRANSFERASE LEUKOTRIENE C4 SYNTHASE lyase activity#GO:0016829;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;icosanoid biosynthetic process#GO:0046456;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;fatty acid derivative metabolic process#GO:1901568;carboxylic acid biosynthetic process#GO:0046394;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 transferase#PC00220 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 HUMAN|HGNC=26402|UniProtKB=Q52LD8 Q52LD8 RFTN2 PTHR17601:SF1 RAFTLIN-RELATED RAFTLIN-2 HUMAN|HGNC=24574|UniProtKB=Q9NUQ6 Q9NUQ6 SPATS2L PTHR15623:SF8 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2-RELATED SPATS2-LIKE PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=21070|UniProtKB=Q9H920 Q9H920 RNF121 PTHR13407:SF1 RNF121 PROTEIN RING FINGER PROTEIN 121 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;ubiquitin-dependent ERAD pathway#GO:0030433;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=25561|UniProtKB=Q9NVL1 Q9NVL1 FAM86C1P PTHR14614:SF117 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT-RELATED N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;nitrogen compound metabolic process#GO:0006807;peptidyl-lysine trimethylation#GO:0018023;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=1305|UniProtKB=Q9NYP8 Q9NYP8 C21orf62 PTHR35658:SF1 RCG58666, ISOFORM CRA_A RCG58666, ISOFORM CRA_A HUMAN|HGNC=13565|UniProtKB=Q9BQ16 Q9BQ16 SPOCK3 PTHR13866:SF21 SPARC OSTEONECTIN TESTICAN-3 cation binding#GO:0043169;extracellular matrix binding#GO:0050840;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=19371|UniProtKB=Q8NE31 Q8NE31 FAM13C PTHR15904:SF19 FAM13 PROTEIN FAM13C HUMAN|HGNC=23208|UniProtKB=Q9GZM3 Q9GZM3 POLR2J2 PTHR13946:SF31 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A-RELATED catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=12553|UniProtKB=P06133 P06133 UGT2B4 PTHR48043:SF12 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2B17-RELATED transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=4449|UniProtKB=P35052 P35052 GPC1 PTHR10822:SF8 GLYPICAN GLYPICAN-1 fibroblast growth factor binding#GO:0017134;growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 fibroblast growth factor receptor signaling pathway#GO:0008543;cellular localization#GO:0051641;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;response to growth factor#GO:0070848;negative regulation of cellular response to growth factor stimulus#GO:0090288;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;regulation of protein localization#GO:0032880;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;protein localization to membrane#GO:0072657;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of protein localization to membrane#GO:1905475;negative regulation of signaling#GO:0023057;localization of cell#GO:0051674;cell motility#GO:0048870;cell communication#GO:0007154;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of signal transduction#GO:0009968;cell migration#GO:0016477;locomotion#GO:0040011 cell junction#GO:0030054;cell surface#GO:0009986;extracellular matrix#GO:0031012;synapse#GO:0045202;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=5965|UniProtKB=Q08334 Q08334 IL10RB PTHR20859:SF50 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-10 RECEPTOR SUBUNIT BETA signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866 HUMAN|HGNC=5209|UniProtKB=P80365 P80365 HSD11B2 PTHR43313:SF2 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 2 dehydrogenase#PC00092 HUMAN|HGNC=4335|UniProtKB=P00367 P00367 GLUD1 PTHR11606:SF25 GLUTAMATE DEHYDROGENASE GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 HUMAN|HGNC=6601|UniProtKB=P49917 P49917 LIG4 PTHR45997:SF1 DNA LIGASE 4 DNA LIGASE 4 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ligase activity#GO:0016874;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=25068|UniProtKB=O43716 O43716 GATC PTHR15004:SF0 UNCHARACTERIZED GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 HUMAN|HGNC=7727|UniProtKB=P46934 P46934 NEDD4 PTHR11254:SF282 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE NEDD4 inorganic molecular entity transmembrane transporter activity#GO:0015318;cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 regulation of dendrite development#GO:0050773;regulation of protein metabolic process#GO:0051246;regulation of metal ion transport#GO:0010959;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;regulation of ion transmembrane transporter activity#GO:0032412;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;proteolysis#GO:0006508;regulation of transmembrane transporter activity#GO:0022898;proteasomal protein catabolic process#GO:0010498;regulation of transporter activity#GO:0032409;cellular protein metabolic process#GO:0044267;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to vacuole#GO:0072666;regulation of transmembrane transport#GO:0034762;regulation of multicellular organismal process#GO:0051239;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;negative regulation of transport#GO:0051051;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of ion transmembrane transport#GO:0034765;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;multicellular organismal process#GO:0032501;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of protein catabolic process#GO:0042176;cation transport#GO:0006812;regulation of multicellular organismal development#GO:2000026;amide transport#GO:0042886;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;neuron differentiation#GO:0030182;catabolic process#GO:0009056;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metal ion transport#GO:0030001;cell morphogenesis involved in differentiation#GO:0000904;transmembrane transport#GO:0055085;regulation of cell development#GO:0060284;organonitrogen compound metabolic process#GO:1901564;cell morphogenesis#GO:0000902;cellular process#GO:0009987;positive regulation of protein metabolic process#GO:0051247;sodium ion transport#GO:0006814;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;intracellular protein transport#GO:0006886;cellular macromolecule catabolic process#GO:0044265;sodium ion transmembrane transport#GO:0035725;negative regulation of molecular function#GO:0044092;cellular localization#GO:0051641;regulation of sodium ion transport#GO:0002028;protein targeting to vacuole#GO:0006623;regulation of catabolic process#GO:0009894;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;membrane organization#GO:0061024;inorganic cation transmembrane transport#GO:0098662;dendrite development#GO:0016358;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;inorganic ion transmembrane transport#GO:0098660;lysosomal transport#GO:0007041;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;protein targeting#GO:0006605;peptide transport#GO:0015833;ion transmembrane transport#GO:0034220;regulation of neuron differentiation#GO:0045664;protein localization#GO:0008104;regulation of neuron projection development#GO:0010975;neuromuscular junction development#GO:0007528;ubiquitin-dependent protein catabolic process#GO:0006511;neuron projection development#GO:0031175;synapse organization#GO:0050808;protein localization to lysosome#GO:0061462;protein transport#GO:0015031;regulation of cell projection organization#GO:0031344;positive regulation of catabolic process#GO:0009896;neuron projection morphogenesis#GO:0048812;regulation of ion transport#GO:0043269;neuron development#GO:0048666;intracellular transport#GO:0046907;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of dendrite morphogenesis#GO:0048814;regulation of cell morphogenesis involved in differentiation#GO:0010769;positive regulation of nitrogen compound metabolic process#GO:0051173;receptor internalization#GO:0031623;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;transport#GO:0006810;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;protein targeting to lysosome#GO:0006622;cation transmembrane transport#GO:0098655;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;receptor-mediated endocytosis#GO:0006898;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;monovalent inorganic cation transport#GO:0015672;regulation of cation transmembrane transport#GO:1904062;vacuolar transport#GO:0007034;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;multicellular organism development#GO:0007275;protein localization to vacuole#GO:0072665;ion transport#GO:0006811;establishment of protein localization to organelle#GO:0072594;dendrite morphogenesis#GO:0048813;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;cell development#GO:0048468;vesicle budding from membrane#GO:0006900;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;cell junction organization#GO:0034330;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;generation of neurons#GO:0048699;proteolysis involved in cellular protein catabolic process#GO:0051603 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 HUMAN|HGNC=30201|UniProtKB=Q9Y6G5 Q9Y6G5 COMMD10 PTHR12333:SF0 COMM DOMAIN CONTAINING PROTEIN 10 COMM DOMAIN-CONTAINING PROTEIN 10 HUMAN|HGNC=30221|UniProtKB=Q9BSL1 Q9BSL1 UBAC1 PTHR46738:SF1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=586|UniProtKB=P13798 P13798 APEH PTHR42776:SF4 SERINE PEPTIDASE S9 FAMILY MEMBER ACYLAMINO-ACID-RELEASING ENZYME serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 HUMAN|HGNC=4800|UniProtKB=Q99714 Q99714 HSD17B10 PTHR43658:SF8 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 2,4-DIENOYL-COA REDUCTASE, MITOCHONDRIAL-RELATED oxidoreductase#PC00176 HUMAN|HGNC=12760|UniProtKB=Q9NSI6 Q9NSI6 BRWD1 PTHR16266:SF26 WD REPEAT DOMAIN 9 BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;regulation of anatomical structure morphogenesis#GO:0022603;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;regulation of cell shape#GO:0008360;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;cytoskeleton organization#GO:0007010;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26269|UniProtKB=Q0P6H9 Q0P6H9 TMEM62 PTHR14795:SF0 HELICASE RELATED TRANSMEMBRANE PROTEIN 62 RNA helicase#PC00032 HUMAN|HGNC=28385|UniProtKB=Q502W6 Q502W6 VWA3B PTHR46785:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B HUMAN|HGNC=16465|UniProtKB=Q96J88 Q96J88 EPSTI1 PTHR22529:SF1 EPITHELIAL-STROMAL INTERACTION PROTEIN 1 EPITHELIAL-STROMAL INTERACTION PROTEIN 1 HUMAN|HGNC=14499|UniProtKB=Q9Y2R9 Q9Y2R9 MRPS7 PTHR11205:SF19 RIBOSOMAL PROTEIN S7 28S RIBOSOMAL PROTEIN S7, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;rRNA binding#GO:0019843 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;ribosomal small subunit biogenesis#GO:0042274;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular#GO:0005622 ribosomal protein#PC00202 HUMAN|HGNC=10549|UniProtKB=Q9UBB4 Q9UBB4 ATXN10 PTHR13255:SF0 ATAXIN-10 ATAXIN-10 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=8724|UniProtKB=P35558 P35558 PCK1 PTHR11561:SF1 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP] cation binding#GO:0043169;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;lyase activity#GO:0016829;ion binding#GO:0043167 liver development#GO:0001889;alcohol biosynthetic process#GO:0046165;lipid catabolic process#GO:0016042;response to extracellular stimulus#GO:0009991;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;neutral lipid metabolic process#GO:0006638;cellular response to hormone stimulus#GO:0032870;regulation of biological quality#GO:0065008;triglyceride biosynthetic process#GO:0019432;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;alcohol metabolic process#GO:0006066;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;response to stress#GO:0006950;cellular carbohydrate metabolic process#GO:0044262;cellular response to organonitrogen compound#GO:0071417;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;monosaccharide metabolic process#GO:0005996;lipid metabolic process#GO:0006629;response to organic cyclic compound#GO:0014070;response to insulin#GO:0032868;epithelium development#GO:0060429;response to peptide hormone#GO:0043434;cellular response to steroid hormone stimulus#GO:0071383;animal organ development#GO:0048513;developmental process#GO:0032502;response to lipid#GO:0033993;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;cellular homeostasis#GO:0019725;cellular response to nitrogen compound#GO:1901699;cellular response to lipid#GO:0071396;system development#GO:0048731;cell differentiation#GO:0030154;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;cellular response to organic cyclic compound#GO:0071407;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;response to organic substance#GO:0010033;carbohydrate biosynthetic process#GO:0016051;cellular response to stimulus#GO:0051716;gland development#GO:0048732;triglyceride metabolic process#GO:0006641;cellular response to chemical stimulus#GO:0070887;glycerolipid biosynthetic process#GO:0045017;multicellular organism development#GO:0007275;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;response to nutrient levels#GO:0031667;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;epithelial cell differentiation#GO:0030855;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;tissue development#GO:0009888;glucose metabolic process#GO:0006006;fatty acid catabolic process#GO:0009062;cellular chemical homeostasis#GO:0055082;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;response to hormone#GO:0009725;response to chemical#GO:0042221;response to starvation#GO:0042594;biological regulation#GO:0065007;hexose metabolic process#GO:0019318;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;response to steroid hormone#GO:0048545 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 Pyruvate metabolism#P02772>Phosphoenolpyruvate Carboxykinase#P03135 HUMAN|HGNC=29489|UniProtKB=Q9NQR1 Q9NQR1 KMT5A PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A protein modifying enzyme#PC00260 HUMAN|HGNC=28467|UniProtKB=Q9BTP7 Q9BTP7 FAAP24 PTHR31786:SF2 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24 binding#GO:0005488;chromatin binding#GO:0003682 membrane-enclosed lumen#GO:0031974;Fanconi anaemia nuclear complex#GO:0043240;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=21389|UniProtKB=Q6MZW2 Q6MZW2 FSTL4 PTHR10913:SF9 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 4 multicellular organismal process#GO:0032501;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 protease inhibitor#PC00191 HUMAN|HGNC=15463|UniProtKB=Q9BVG9 Q9BVG9 PTDSS2 PTHR15362:SF7 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 2 transferase#PC00220 HUMAN|HGNC=11735|UniProtKB=Q9BXU3 Q9BXU3 TEX13A PTHR23111:SF89 ZINC FINGER PROTEIN TESTIS-EXPRESSED PROTEIN 13A HUMAN|HGNC=19990|UniProtKB=Q9UJX5 Q9UJX5 ANAPC4 PTHR13260:SF0 ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4 ANAPHASE-PROMOTING COMPLEX SUBUNIT 4 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;protein catabolic process#GO:0030163;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;chromosome segregation#GO:0007059;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic sister chromatid segregation#GO:0033047;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;protein K11-linked ubiquitination#GO:0070979;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;positive regulation of organelle organization#GO:0010638;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;mitotic cell cycle process#GO:1903047;positive regulation of cell cycle process#GO:0090068;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;positive regulation of mitotic nuclear division#GO:0045840;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;metaphase/anaphase transition of cell cycle#GO:0044784;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of mitotic cell cycle#GO:0007346 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;nuclear periphery#GO:0034399;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=23984|UniProtKB=Q9GZY0 Q9GZY0 NXF2 PTHR10662:SF46 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=694|UniProtKB=P36405 P36405 ARL3 PTHR45697:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=27984|UniProtKB=Q6ZMY9 Q6ZMY9 ZNF517 PTHR24379:SF20 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 517 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=24431|UniProtKB=O95678 O95678 KRT75 PTHR45616:SF13 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 75 HUMAN|HGNC=19901|UniProtKB=Q5VZM2 Q5VZM2 RRAGB PTHR11259:SF4 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN B pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 signal transduction#GO:0007165;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to starvation#GO:0009267;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of autophagy#GO:0010506;cellular metabolic process#GO:0044237;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;nucleus#GO:0005634;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=11029|UniProtKB=P48751 P48751 SLC4A3 PTHR11453:SF15 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN 3 secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;anion:anion antiporter activity#GO:0015301;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=20635|UniProtKB=Q14997 Q14997 PSME4 PTHR32170:SF3 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;peptidase activity#GO:0008233;enzyme regulator activity#GO:0030234;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030;proteasome binding#GO:0070628;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17105|UniProtKB=Q8N1M1 Q8N1M1 BEST3 PTHR10736:SF2 BESTROPHIN BESTROPHIN-3 ion channel#PC00133 HUMAN|HGNC=16522|UniProtKB=Q8N3Y3 Q8N3Y3 LARGE2 PTHR12270:SF23 GLYCOSYLTRANSFERASE-RELATED LARGE XYLOSYL- AND GLUCURONYLTRANSFERASE 2 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;xylosyltransferase activity#GO:0042285;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 glycosyltransferase#PC00111 HUMAN|HGNC=15468|UniProtKB=Q9NP97 Q9NP97 DYNLRB1 PTHR10779:SF17 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 1 protein binding#GO:0005515;binding#GO:0005488 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 microtubule organizing center#GO:0005815;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=23324|UniProtKB=Q3SY17 Q3SY17 SLC25A52 PTHR46131:SF2 SD08549P SOLUTE CARRIER FAMILY 25 MEMBER 51-RELATED HUMAN|HGNC=17994|UniProtKB=Q96QT4 Q96QT4 TRPM7 PTHR13800:SF8 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 7 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;divalent inorganic cation homeostasis#GO:0072507;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cation transport#GO:0006812;chemical homeostasis#GO:0048878;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;localization#GO:0051179;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;biological regulation#GO:0065007;divalent inorganic cation transport#GO:0072511 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=15204|UniProtKB=Q8NGJ8 Q8NGJ8 OR51S1 PTHR26450:SF73 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51S1 transmembrane signal receptor#PC00197 HUMAN|HGNC=14008|UniProtKB=Q9BW11 Q9BW11 MXD3 PTHR11969:SF6 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=14336|UniProtKB=Q9HB19 Q9HB19 PLEKHA2 PTHR14336:SF5 TANDEM PH DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 2 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=854|UniProtKB=P21281 P21281 ATP6V1B2 PTHR43389:SF5 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B, BRAIN ISOFORM ATP synthase#PC00002 HUMAN|HGNC=10079|UniProtKB=Q9HAU8 Q9HAU8 RNPEPL1 PTHR45726:SF2 FAMILY NOT NAMED AMINOPEPTIDASE RNPEPL1 HUMAN|HGNC=25771|UniProtKB=Q9H974 Q9H974 QTRT2 PTHR46064:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA processing factor#PC00147 HUMAN|HGNC=28975|UniProtKB=Q15018 Q15018 ABRAXAS2 PTHR31728:SF1 ABRAXAS FAMILY MEMBER BRISC COMPLEX SUBUNIT ABRAXAS 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;macromolecule modification#GO:0043412;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;protein K63-linked deubiquitination#GO:0070536;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;mitotic spindle assembly#GO:0090307;proteolysis#GO:0006508;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic nuclear division#GO:0140014;spindle organization#GO:0007051;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;cell cycle#GO:0007049;organelle fission#GO:0048285 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=17453|UniProtKB=Q86UV6 Q86UV6 TRIM74 PTHR24103:SF662 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 73-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=26576|UniProtKB=Q8NBH2 Q8NBH2 KY PTHR46333:SF3 CYTOKINESIS PROTEIN 3 KYPHOSCOLIOSIS PEPTIDASE HUMAN|HGNC=21625|UniProtKB=Q5XXA6 Q5XXA6 ANO1 PTHR12308:SF13 NGEP-RELATED ANOCTAMIN-1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;inorganic anion transport#GO:0015698;anion transmembrane transport#GO:0098656 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=16966|UniProtKB=Q15326 Q15326 ZMYND11 PTHR46379:SF1 ZINC FINGER MYND DOMAIN-CONTAINING ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11 transcription cofactor#PC00217 HUMAN|HGNC=9352|UniProtKB=Q06830 Q06830 PRDX1 PTHR10681:SF111 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-1 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;cellular process#GO:0009987;cell activation#GO:0001775;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to oxidative stress#GO:0034599;catabolic process#GO:0009056;response to toxic substance#GO:0009636;cellular response to stress#GO:0033554;leukocyte activation#GO:0045321;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 peroxidase#PC00180 HUMAN|HGNC=1065|UniProtKB=Q9H2G9 Q9H2G9 BLZF1 PTHR13066:SF2 BASIC LEUCINE ZIPPER NUCLEAR FACTOR 1 BLZF1 PROTEIN GOLGIN-45 protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=2983|UniProtKB=P04053 P04053 DNTT PTHR11276:SF21 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA NUCLEOTIDYLEXOTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;DNA polymerase activity#GO:0034061;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-directed DNA polymerase#PC00018 HUMAN|HGNC=11621|UniProtKB=P20823 P20823 HNF1A PTHR11568:SF4 HEPATOCYTE NUCLEAR FACTOR 1 HEPATOCYTE NUCLEAR FACTOR 1-ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=8887|UniProtKB=P0DJD9 P0DJD9 PGA5 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED HUMAN|HGNC=29122|UniProtKB=Q8N3P4 Q8N3P4 VPS8 PTHR42968:SF11 WD REPEAT-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle fusion#GO:0006906;membrane fusion#GO:0061025;establishment of localization#GO:0051234;membrane organization#GO:0061024;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25648|UniProtKB=Q8N5J2 Q8N5J2 MINDY1 PTHR18063:SF7 NF-E2 INDUCIBLE PROTEIN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-1 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein K48-linked deubiquitination#GO:0071108;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;intracellular#GO:0005622 HUMAN|HGNC=16980|UniProtKB=Q02985 Q02985 CFHR3 PTHR45785:SF4 COMPLEMENT FACTOR H-RELATED COMPLEMENT FACTOR H-RELATED PROTEIN 3-RELATED HUMAN|HGNC=4945|UniProtKB=P05538 P05538 HLA-DQB2 PTHR19944:SF68 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ BETA 2 CHAIN major histocompatibility complex protein#PC00149 HUMAN|HGNC=24674|UniProtKB=Q8TES7 Q8TES7 FBF1 PTHR33689:SF1 FAS-BINDING FACTOR 1 FAS-BINDING FACTOR 1 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=9771|UniProtKB=Q13636 Q13636 RAB31 PTHR24073:SF588 DRAB5-RELATED RAS-RELATED PROTEIN RAB-31 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=28317|UniProtKB=Q8WU08 Q8WU08 STK32A PTHR24356:SF143 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE 32A transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=11914|UniProtKB=Q9Y5U5 Q9Y5U5 TNFRSF18 PTHR47388:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 18 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 18 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological adhesion#GO:0022610;biological regulation#GO:0065007;positive regulation of cell adhesion#GO:0045785;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=20968|UniProtKB=Q9H6W3 Q9H6W3 RIOX1 PTHR13096:SF4 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 1 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;chromosome organization#GO:0051276;organelle organization#GO:0006996;protein demethylation#GO:0006482;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;demethylation#GO:0070988;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6818|UniProtKB=Q13021 Q13021 MALL PTHR22776:SF24 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MAL-LIKE PROTEIN structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=7180|UniProtKB=Q10571 Q10571 MN1 PTHR15821:SF0 PROTEIN MN1 TRANSCRIPTIONAL ACTIVATOR MN1 HUMAN|HGNC=3122|UniProtKB=O00292 O00292 LEFTY2 PTHR11848:SF232 TGF-BETA FAMILY LEFT-RIGHT DETERMINATION FACTOR 2 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=14656|UniProtKB=Q8TD84 Q8TD84 DSCAML1 PTHR10075:SF72 BASIGIN RELATED DOWN SYNDROME CELL ADHESION MOLECULE-LIKE PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 HUMAN|HGNC=6026|UniProtKB=P25024 P25024 CXCR1 PTHR10489:SF916 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 1 cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;neutrophil migration#GO:1990266;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;granulocyte chemotaxis#GO:0071621;response to chemical#GO:0042221;myeloid leukocyte migration#GO:0097529;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;leukocyte chemotaxis#GO:0030595;locomotion#GO:0040011;chemotaxis#GO:0006935;taxis#GO:0042330 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=8620|UniProtKB=P26367 P26367 PAX6 PTHR45636:SF21 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=27902|UniProtKB=Q0P5N6 Q0P5N6 ARL16 PTHR46688:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 HUMAN|HGNC=12189|UniProtKB=A0A5B0 A0A5B0 TRBV14 PTHR23268:SF38 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 14 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=25793|UniProtKB=Q8IZ21 Q8IZ21 PHACTR4 PTHR12751:SF4 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular developmental process#GO:0048869;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;multicellular organism development#GO:0007275;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;mesenchymal cell differentiation#GO:0048762;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;actin filament-based process#GO:0030029;neural crest cell differentiation#GO:0014033;organelle organization#GO:0006996;mesenchyme development#GO:0060485;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;stem cell differentiation#GO:0048863;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 phosphatase modulator#PC00184 HUMAN|HGNC=10941|UniProtKB=P43003 P43003 SLC1A3 PTHR11958:SF24 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 1 primary active transporter#PC00068 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 HUMAN|HGNC=9006|UniProtKB=O75364 O75364 PITX3 PTHR45882:SF2 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=2435|UniProtKB=P15509 P15509 CSF2RA PTHR23036:SF94 CYTOKINE RECEPTOR GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=592|UniProtKB=P98170 P98170 XIAP PTHR10044:SF115 INHIBITOR OF APOPTOSIS E3 UBIQUITIN-PROTEIN LIGASE XIAP cysteine-type peptidase activity#GO:0008234;peptidase inhibitor activity#GO:0030414;ubiquitin-protein transferase activity#GO:0004842;protease binding#GO:0002020;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;transferase activity#GO:0016740;cysteine-type endopeptidase activity#GO:0004197;ubiquitin protein ligase activity#GO:0061630;hydrolase activity#GO:0016787;ubiquitin-like protein ligase activity#GO:0061659;cysteine-type endopeptidase inhibitor activity#GO:0004869;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;spindle organization#GO:0007051;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;negative regulation of endopeptidase activity#GO:0010951;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cell-cell signaling by wnt#GO:0198738;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043154;positive regulation of cell communication#GO:0010647;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;mitotic spindle organization#GO:0007052;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of catalytic activity#GO:0050790;positive regulation of Wnt signaling pathway#GO:0030177;mitotic cell cycle process#GO:1903047;protein processing#GO:0016485;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;mitotic spindle assembly#GO:0090307;cell death#GO:0008219;mitotic nuclear division#GO:0140014;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of canonical Wnt signaling pathway#GO:0060828;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;microtubule-based process#GO:0007017;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell cycle#GO:0007049;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 protease inhibitor#PC00191 Apoptosis signaling pathway#P00006>XIAP#P00304 HUMAN|HGNC=6383|UniProtKB=P01042 P01042 KNG1 PTHR13814:SF12 FETUIN KININOGEN-1 cysteine-type peptidase activity#GO:0008234;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;cysteine-type endopeptidase inhibitor activity#GO:0004869;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 inorganic ion homeostasis#GO:0098771;regulation of protein metabolic process#GO:0051246;divalent inorganic cation homeostasis#GO:0072507;regulation of nitrogen compound metabolic process#GO:0051171;regulation of coagulation#GO:0050818;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of biological process#GO:0050789;regulation of wound healing#GO:0061041;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;cellular cation homeostasis#GO:0030003;regulation of multicellular organismal process#GO:0051239;negative regulation of coagulation#GO:0050819;macromolecule metabolic process#GO:0043170;negative regulation of endopeptidase activity#GO:0010951;regulation of body fluid levels#GO:0050878;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;response to wounding#GO:0009611;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;metal ion homeostasis#GO:0055065;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular metal ion homeostasis#GO:0006875;negative regulation of cellular metabolic process#GO:0031324;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;cellular macromolecule metabolic process#GO:0044260;wound healing#GO:0042060;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;negative regulation of multicellular organismal process#GO:0051241;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of peptidase activity#GO:0010466;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;hemostasis#GO:0007599;coagulation#GO:0050817;regulation of response to wounding#GO:1903034;regulation of primary metabolic process#GO:0080090;cellular chemical homeostasis#GO:0055082;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of blood coagulation#GO:0030195;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;blood coagulation#GO:0007596;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>Bradykinin#P00438;Blood coagulation#P00011>Kininogen#P00451;Blood coagulation#P00011>HMWK#P00413 HUMAN|HGNC=6783|UniProtKB=P20916 P20916 MAG PTHR12035:SF107 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN MYELIN-ASSOCIATED GLYCOPROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=6823|UniProtKB=Q9UKM7 Q9UKM7 MAN1B1 PTHR11742:SF55 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=37221|UniProtKB=P86479 P86479 PRR20C PTHR38819:SF1 PROLINE-RICH PROTEIN 20A-RELATED PROLINE-RICH PROTEIN 20A-RELATED HUMAN|HGNC=8785|UniProtKB=P16499 P16499 PDE6A PTHR11347:SF115 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;system development#GO:0048731;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;retina development in camera-type eye#GO:0060041;eye development#GO:0001654;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423;signaling#GO:0023052 bounding membrane of organelle#GO:0098588;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 phosphodiesterase#PC00185 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEalphabeta#P00759 HUMAN|HGNC=19274|UniProtKB=Q8N0Z6 Q8N0Z6 TTC5 PTHR26312:SF87 TETRATRICOPEPTIDE REPEAT PROTEIN 5 TETRATRICOPEPTIDE REPEAT PROTEIN 5 HUMAN|HGNC=27160|UniProtKB=Q6IC83 Q6IC83 C22orf42 PTHR15880:SF1 ASPARTATE-RICH PROTEIN 1 CHROMOSOME 22 OPEN READING FRAME 42 HUMAN|HGNC=12462|UniProtKB=P57075 P57075 UBASH3A PTHR16469:SF7 FAMILY NOT NAMED UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING PROTEIN A immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;activation of immune response#GO:0002253;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;regulation of signal transduction#GO:0009966;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of cell communication#GO:0010646;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of immune system process#GO:0002683;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=12288|UniProtKB=P03979 P03979 TRGV3 PTHR19256:SF45 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED HUMAN|HGNC=26161|UniProtKB=P57737 P57737 CORO7 PTHR10856:SF20 CORONIN CORONIN-7 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 non-motor actin binding protein#PC00165 HUMAN|HGNC=24308|UniProtKB=Q96KA5 Q96KA5 CLPTM1L PTHR21347:SF12 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED CLEFT LIP AND PALATE TRANSMEMBRANE PROTEIN 1-LIKE PROTEIN cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=16724|UniProtKB=Q9H4R4 Q9H4R4 NCOR1P1 PTHR13992:SF5 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR NUCLEAR RECEPTOR COREPRESSOR 1-RELATED binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;DNA-binding transcription factor binding#GO:0140297 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>N-CoR#P00770 HUMAN|HGNC=1980|UniProtKB=O75339 O75339 CILP PTHR15031:SF3 CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP CARTILAGE INTERMEDIATE LAYER PROTEIN 1 HUMAN|HGNC=25251|UniProtKB=Q9H095 Q9H095 IQCG PTHR14871:SF1 DYNEIN REGULATORY COMPLEX PROTEIN 9 DYNEIN REGULATORY COMPLEX PROTEIN 9 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 cytoplasm#GO:0005737;motile cilium#GO:0031514;protein-containing complex#GO:0032991;intracellular#GO:0005622;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=26215|UniProtKB=Q6P4A8 Q6P4A8 PLBD1 PTHR12370:SF1 PHOSPHOLIPASE B-RELATED PHOSPHOLIPASE B-LIKE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 phospholipase#PC00186 HUMAN|HGNC=621|UniProtKB=Q13564 Q13564 NAE1 PTHR10953:SF29 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=26960|UniProtKB=Q96KV7 Q96KV7 WDR90 PTHR13720:SF24 WD-40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 90 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=34490|UniProtKB=Q6UX52 Q6UX52 C17orf99 PTHR11481:SF67 IMMUNOGLOBULIN FC RECEPTOR PROTEIN IL-40 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological adhesion#GO:0022610;biological regulation#GO:0065007;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=15936|UniProtKB=Q14686 Q14686 NCOA6 PTHR15690:SF0 NUCLEAR RECEPTOR COACTIVATOR 6 NUCLEAR RECEPTOR COACTIVATOR 6 transcription coactivator activity#GO:0003713;nuclear receptor transcription coactivator activity#GO:0030374;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=10303|UniProtKB=P26373 P26373 RPL13 PTHR11722:SF4 60S RIBOSOMAL PROTEIN L13 60S RIBOSOMAL PROTEIN L13 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=14626|UniProtKB=Q96FF9 Q96FF9 CDCA5 PTHR31092:SF2 SORORIN SORORIN HUMAN|HGNC=15630|UniProtKB=O14776 O14776 TCERG1 PTHR15377:SF7 TRANSCRIPTION ELONGATION REGULATOR 1 TRANSCRIPTION ELONGATION REGULATOR 1 enzyme binding#GO:0019899;transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription regulator activity#GO:0140110;RNA polymerase binding#GO:0070063;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 general transcription factor#PC00259 HUMAN|HGNC=27019|UniProtKB=Q5TZ20 Q5TZ20 OR2G6 PTHR26453:SF110 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2G6 transmembrane signal receptor#PC00197 HUMAN|HGNC=16385|UniProtKB=Q96P11 Q96P11 NSUN5 PTHR22807:SF68 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=51261|UniProtKB=P0DMV1 P0DMV1 CT45A8 PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED CANCER/TESTIS ANTIGEN FAMILY 45 MEMBER A1-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 RNA helicase#PC00032 HUMAN|HGNC=5914|UniProtKB=A0A0A0MS00 A0A0A0MS00 IGLV3-32 PTHR23267:SF364 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-19-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=23597|UniProtKB=Q701N4 Q701N4 KRTAP5-2 PTHR23262:SF25 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-10-RELATED HUMAN|HGNC=30278|UniProtKB=Q14699 Q14699 RFTN1 PTHR17601:SF3 RAFTLIN-RELATED RAFTLIN HUMAN|HGNC=2226|UniProtKB=Q9Y215 Q9Y215 COLQ PTHR24023:SF861 COLLAGEN ALPHA ACETYLCHOLINESTERASE COLLAGENIC TAIL PEPTIDE carbohydrate derivative binding#GO:0097367;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;heparin binding#GO:0008201;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;enzyme linked receptor protein signaling pathway#GO:0007167;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;extracellular region#GO:0005576;basement membrane#GO:0005604;collagen trimer#GO:0005581;supramolecular polymer#GO:0099081;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023 extracellular matrix structural protein#PC00103 HUMAN|HGNC=8951|UniProtKB=P07093 P07093 SERPINE2 PTHR11461:SF48 SERINE PROTEASE INHIBITOR, SERPIN GLIA-DERIVED NEXIN serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=17028|UniProtKB=Q96H20 Q96H20 SNF8 PTHR12806:SF1 EAP30 SUBUNIT OF ELL COMPLEX VACUOLAR-SORTING PROTEIN SNF8 protein catabolic process in the vacuole#GO:0007039;endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;multivesicular body sorting pathway#GO:0071985;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular macromolecule localization#GO:0070727;cellular protein catabolic process#GO:0044257;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=6897|UniProtKB=P27448 P27448 MARK3 PTHR24346:SF1 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MAP/MICROTUBULE AFFINITY-REGULATING KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=18591|UniProtKB=Q8TD19 Q8TD19 NEK9 PTHR44535:SF1 PROTEIN CBG16200 SERINE/THREONINE-PROTEIN KINASE NEK9 HUMAN|HGNC=11595|UniProtKB=O95935 O95935 TBX18 PTHR11267:SF20 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX18 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=21717|UniProtKB=P86790 P86790 CCZ1B PTHR13056:SF0 UNCHARACTERIZED VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=29422|UniProtKB=Q6ZW76 Q6ZW76 ANKS3 PTHR24184:SF21 SI:CH211-189E2.2 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=8920|UniProtKB=O75151 O75151 PHF2 PTHR23123:SF14 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE PHF2 molecular function regulator#GO:0098772;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;demethylation#GO:0070988;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein demethylation#GO:0006482;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=12865|UniProtKB=A6NM28 A6NM28 ZFP92 PTHR24377:SF634 IP01015P-RELATED ZINC FINGER PROTEIN 92 HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=9530|UniProtKB=P25786 P25786 PSMA1 PTHR11599:SF12 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-1 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome core complex, alpha-subunit complex#GO:0019773;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=32466|UniProtKB=P0CB33 P0CB33 ZNF735 PTHR24384:SF228 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 722, PSEUDOGENE-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=17111|UniProtKB=Q8TE59 Q8TE59 ADAMTS19 PTHR13723:SF197 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 19 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=1378|UniProtKB=Q9Y2D0 Q9Y2D0 CA5B PTHR18952:SF25 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 5B, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=27234|UniProtKB=Q86X53 Q86X53 ERICH1 PTHR22444:SF1 UNCHARACTERIZED GLUTAMATE-RICH PROTEIN 1 HUMAN|HGNC=23400|UniProtKB=Q9BY50 Q9BY50 SEC11C PTHR10806:SF12 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11C hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;signal peptide processing#GO:0006465;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 serine protease#PC00203 Endothelin signaling pathway#P00019>signal peptidase#P00573;Vasopressin synthesis#P04395>Signal Peptidase#P04589 HUMAN|HGNC=11433|UniProtKB=Q16623 Q16623 STX1A PTHR19957:SF84 SYNTAXIN SYNTAXIN-1A protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulated exocytosis#GO:0045055;amide transport#GO:0042886;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of neurotransmitter levels#GO:0001505;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;SNARE complex#GO:0031201;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;presynaptic membrane#GO:0042734;vesicle#GO:0031982;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 SNARE protein#PC00034 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 HUMAN|HGNC=1628|UniProtKB=P08571 P08571 CD14 PTHR10630:SF3 MONOCYTE DIFFERENTIATION ANTIGEN CD14 MONOCYTE DIFFERENTIATION ANTIGEN CD14 carbohydrate derivative binding#GO:0097367;lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;binding#GO:0005488 positive regulation of gene expression#GO:0010628;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of localization#GO:0032879;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;secretion#GO:0046903;defense response#GO:0006952;regulation of protein localization#GO:0032880;regulation of protein secretion#GO:0050708;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;cellular response to biotic stimulus#GO:0071216;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;response to lipopolysaccharide#GO:0032496;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;establishment of protein localization to extracellular region#GO:0035592;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;positive regulation of secretion by cell#GO:1903532;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;regulation of peptide transport#GO:0090087;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;cellular response to lipopolysaccharide#GO:0071222;RNA metabolic process#GO:0016070;positive regulation of protein secretion#GO:0050714;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;response to lipid#GO:0033993;biosynthetic process#GO:0009058;toll-like receptor 4 signaling pathway#GO:0034142;inflammatory response#GO:0006954;cytokine production#GO:0001816;cellular response to lipid#GO:0071396;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;response to bacterium#GO:0009617;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;signal release#GO:0023061;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein transport#GO:0051223;signaling#GO:0023052;cell-cell signaling#GO:0007267;secretion by cell#GO:0032940;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of DNA-binding transcription factor activity#GO:0051091;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;regulation of nucleic acid-templated transcription#GO:1903506;response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;regulation of secretion by cell#GO:1903530;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;establishment of protein localization#GO:0045184;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;establishment of localization#GO:0051234;regulation of NIK/NF-kappaB signaling#GO:1901222;regulation of secretion#GO:0051046;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of cytokine production#GO:0001819;response to molecule of bacterial origin#GO:0002237;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;positive regulation of secretion#GO:0051047;RNA biosynthetic process#GO:0032774;positive regulation of transport#GO:0051050;toll-like receptor signaling pathway#GO:0002224;peptide transport#GO:0015833;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;protein transport#GO:0015031;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of establishment of protein localization#GO:0070201;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;macromolecule localization#GO:0033036;transport#GO:0006810;positive regulation of peptide secretion#GO:0002793;peptide secretion#GO:0002790;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of NIK/NF-kappaB signaling#GO:1901224;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;cellular response to oxygen-containing compound#GO:1901701;positive regulation of metabolic process#GO:0009893;regulation of transport#GO:0051049;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;cellular macromolecule biosynthetic process#GO:0034645;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;NIK/NF-kappaB signaling#GO:0038061;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane protein complex#GO:0098796;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;side of membrane#GO:0098552;whole membrane#GO:0098805;external side of plasma membrane#GO:0009897;receptor complex#GO:0043235;cell surface#GO:0009986;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;membrane raft#GO:0045121;membrane microdomain#GO:0098857;membrane region#GO:0098589;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>CD14#P01373 HUMAN|HGNC=18477|UniProtKB=Q9UKD2 Q9UKD2 MRTO4 PTHR45841:SF2 MRNA TURNOVER PROTEIN 4 MRTO4 MRNA TURNOVER PROTEIN 4 HOMOLOG RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684 HUMAN|HGNC=8666|UniProtKB=Q9UN75 Q9UN75 PCDHA12 PTHR24028:SF76 CADHERIN-87A PROTOCADHERIN ALPHA-12 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=18864|UniProtKB=Q96L42 Q96L42 KCNH8 PTHR10217:SF380 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 8 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=33270|UniProtKB=P0DMU8 P0DMU8 CT45A5 PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED CANCER/TESTIS ANTIGEN FAMILY 45 MEMBER A1-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 RNA helicase#PC00032 HUMAN|HGNC=26337|UniProtKB=Q76KX8 Q76KX8 ZNF534 PTHR24377:SF854 IP01015P-RELATED ZINC FINGER PROTEIN 534 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=9402|UniProtKB=P05129 P05129 PRKCG PTHR24356:SF162 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C GAMMA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;VEGF signaling pathway#P00056>PKC#P01425;FGF signaling pathway#P00021>PKC#P00648;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Apoptosis signaling pathway#P00006>PKCs#P00318 HUMAN|HGNC=129|UniProtKB=P68133 P68133 ACTA1 PTHR11937:SF193 ACTIN ACTIN, ALPHA SKELETAL MUSCLE actin and actin related protein#PC00039 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 HUMAN|HGNC=1488|UniProtKB=P52907 P52907 CAPZA1 PTHR10653:SF5 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cortical actin cytoskeleton#GO:0030864;actin cortical patch#GO:0030479;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|Gene=YJ012_HUMAN|UniProtKB=Q8N9G6 Q8N9G6 - PTHR11639:SF71 S100 CALCIUM-BINDING PROTEIN UPF0607 PROTEIN ENSP00000332738-RELATED protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=17650|UniProtKB=Q7Z6J0 Q7Z6J0 SH3RF1 PTHR14167:SF44 SH3 DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE SH3RF1 HUMAN|HGNC=2466|UniProtKB=Q6UVK1 Q6UVK1 CSPG4 PTHR15036:SF17 PIKACHURIN-LIKE PROTEIN CHONDROITIN SULFATE PROTEOGLYCAN 4 HUMAN|HGNC=28110|UniProtKB=Q8WVY7 Q8WVY7 UBLCP1 PTHR32054:SF0 HEAVY CHAIN, PUTATIVE, EXPRESSED-RELATED-RELATED UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 HUMAN|HGNC=21610|UniProtKB=Q9C0E8 Q9C0E8 LNPK PTHR22166:SF12 ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;organelle organization#GO:0006996 endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=723|UniProtKB=P52961 P52961 ART1 PTHR10339:SF19 ADP-RIBOSYLTRANSFERASE GPI-LINKED NAD(P)(+)--ARGININE ADP-RIBOSYLTRANSFERASE 1 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=6228|UniProtKB=Q14722 Q14722 KCNAB1 PTHR43150:SF7 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;protein binding#GO:0005515;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 negative regulation of biological process#GO:0048519;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;oxidation-reduction process#GO:0055114;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;negative regulation of transport#GO:0051051;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;negative regulation of molecular function#GO:0044092 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;side of membrane#GO:0098552;cation channel complex#GO:0034703;axon#GO:0030424;extrinsic component of membrane#GO:0019898;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 HUMAN|HGNC=17751|UniProtKB=Q6Q6R5 Q6Q6R5 CRIP3 PTHR46074:SF4 CYSTEINE-RICH PROTEIN CRIP FAMILY MEMBER CYSTEINE-RICH PROTEIN 3 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=29507|UniProtKB=Q9HB40 Q9HB40 SCPEP1 PTHR11802:SF3 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 serine protease#PC00203 HUMAN|HGNC=5147|UniProtKB=P32754 P32754 HPD PTHR11959:SF12 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;tyrosine metabolic process#GO:0006570;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;aromatic amino acid family metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 oxygenase#PC00177 HUMAN|HGNC=961|UniProtKB=Q9UIG0 Q9UIG0 BAZ1B PTHR46802:SF1 TYROSINE-PROTEIN KINASE BAZ1B TYROSINE-PROTEIN KINASE BAZ1B HUMAN|HGNC=30212|UniProtKB=Q9HCD6 Q9HCD6 TANC2 PTHR24166:SF21 ROLLING PEBBLES, ISOFORM B PROTEIN TANC2 HUMAN|HGNC=18160|UniProtKB=Q9Y603 Q9Y603 ETV7 PTHR11849:SF77 ETS TRANSCRIPTION FACTOR ETV7 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=11278|UniProtKB=O15270 O15270 SPTLC2 PTHR13693:SF79 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transaminase#PC00216 HUMAN|HGNC=124|UniProtKB=P13686 P13686 ACP5 PTHR10161:SF14 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 cation binding#GO:0043169;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;ferrous iron binding#GO:0008198;binding#GO:0005488;catalytic activity#GO:0003824;iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;ion binding#GO:0043167;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181 HUMAN|HGNC=5925|UniProtKB=A0A075B6I7 A0A075B6I7 IGLV5-48 PTHR23267:SF325 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 5-37-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=7471|UniProtKB=Q8IVG9 Q8IVG9 MT-RNR2 PTHR33895:SF15 HUMANIN-LIKE 4 HUMANIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=7940|UniProtKB=P16860 P16860 NPPB PTHR14066:SF10 ATRIAL NATRIURETIC FACTOR PRECURSOR NATRIURETIC PEPTIDES B receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;molecular function regulator#GO:0098772;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427 cyclic nucleotide metabolic process#GO:0009187;system process#GO:0003008;purine nucleotide biosynthetic process#GO:0006164;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;enzyme linked receptor protein signaling pathway#GO:0007167;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;circulatory system process#GO:0003013;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;blood circulation#GO:0008015;signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;second-messenger-mediated signaling#GO:0019932;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;neuropeptide signaling pathway#GO:0007218;cellular nitrogen compound biosynthetic process#GO:0044271;signaling#GO:0023052;metabolic process#GO:0008152;negative regulation of blood pressure#GO:0045776;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;regulation of systemic arterial blood pressure#GO:0003073;cellular biosynthetic process#GO:0044249;cGMP-mediated signaling#GO:0019934;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of blood pressure#GO:0008217;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;nucleobase-containing small molecule metabolic process#GO:0055086;cyclic-nucleotide-mediated signaling#GO:0019935;purine ribonucleotide biosynthetic process#GO:0009152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26698|UniProtKB=Q8N9V2 Q8N9V2 TRIML1 PTHR24103:SF617 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=30826|UniProtKB=Q86UY8 Q86UY8 NT5DC3 PTHR12103:SF11 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173 HUMAN|HGNC=24963|UniProtKB=Q96MG2 Q96MG2 JSRP1 PTHR22397:SF2 JUNCTIONAL SARCOPLASMIC RETICULUM PROTEIN 1 JUNCTIONAL SARCOPLASMIC RETICULUM PROTEIN 1 HUMAN|HGNC=19196|UniProtKB=Q8IXZ3 Q8IXZ3 SP8 PTHR23235:SF25 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP8 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 Huntington disease#P00029>Sp1#P00803 HUMAN|HGNC=2608|UniProtKB=Q16696 Q16696 CYP2A13 PTHR24300:SF354 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2A13 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;secondary metabolic process#GO:0019748;cellular response to chemical stimulus#GO:0070887;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;response to stimulus#GO:0050896;organic cyclic compound metabolic process#GO:1901360;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 oxygenase#PC00177 Nicotine degradation#P05914>CYP2A6#P05984 HUMAN|HGNC=3811|UniProtKB=P55316 P55316 FOXG1 PTHR46617:SF3 FORKHEAD BOX PROTEIN G1 FORKHEAD BOX PROTEIN G1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=3553|UniProtKB=O00519 O00519 FAAH PTHR45847:SF3 FATTY ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular lipid catabolic process#GO:0044242;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 hydrolase#PC00121 Anandamide degradation#P05728>FAAH#P05741 HUMAN|HGNC=13548|UniProtKB=Q9GZP7 Q9GZP7 VN1R1 PTHR24062:SF69 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 1 transmembrane signal receptor#PC00197 HUMAN|HGNC=30173|UniProtKB=Q9HAS0 Q9HAS0 C17orf75 PTHR14416:SF2 PROTEIN NJMU-R1 PROTEIN NJMU-R1 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle targeting#GO:0006903;establishment of organelle localization#GO:0051656 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=16449|UniProtKB=A6NLU0 A6NLU0 RFPL4A PTHR25462:SF245 BONUS, ISOFORM C-RELATED RET FINGER PROTEIN-LIKE 4A-RELATED HUMAN|HGNC=9019|UniProtKB=Q9Y2B9 Q9Y2B9 PKIG PTHR15416:SF5 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI CAMP-DEPENDENT PROTEIN KINASE INHIBITOR GAMMA carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;protein phosphorylation#GO:0006468;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase inhibitor#PC00139 HUMAN|HGNC=4522|UniProtKB=P48145 P48145 NPBWR1 PTHR24229:SF47 NEUROPEPTIDES RECEPTOR NEUROPEPTIDES B/W RECEPTOR TYPE 1 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=33205|UniProtKB=Q1AE95 Q1AE95 TMEM183B PTHR20988:SF2 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 183A-RELATED HUMAN|HGNC=30619|UniProtKB=Q2M3C7 Q2M3C7 SPHKAP PTHR10226:SF7 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN SPHKAP protein kinase A binding#GO:0051018;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6255|UniProtKB=P48048 P48048 KCNJ1 PTHR11767:SF6 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=12015|UniProtKB=P07202 P07202 TPO PTHR11475:SF60 OXIDASE/PEROXIDASE THYROID PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180 HUMAN|HGNC=3008|UniProtKB=Q9NY33 Q9NY33 DPP3 PTHR23422:SF11 DIPEPTIDYL PEPTIDASE III-RELATED DIPEPTIDYL PEPTIDASE 3 metalloprotease#PC00153 HUMAN|HGNC=8095|UniProtKB=P54368 P54368 OAZ1 PTHR10279:SF8 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 1 carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;ornithine decarboxylase activity#GO:0004586;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular function regulator#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule catabolic process#GO:0009057;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;positive regulation of protein catabolic process#GO:0045732;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=6895|UniProtKB=Q9UEW3 Q9UEW3 MARCO PTHR24023:SF897 COLLAGEN ALPHA MACROPHAGE RECEPTOR MARCO structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=1474|UniProtKB=P40121 P40121 CAPG PTHR11977:SF127 VILLIN MACROPHAGE-CAPPING PROTEIN non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 HUMAN|HGNC=26708|UniProtKB=Q6ZTR5 Q6ZTR5 CFAP47 PTHR45912:SF3 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 47 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 47 structural protein#PC00211 HUMAN|HGNC=1811|UniProtKB=Q9Y232 Q9Y232 CDYL PTHR43684:SF5 FAMILY NOT NAMED CHROMODOMAIN Y-LIKE PROTEIN transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=13358|UniProtKB=Q8TDD5 Q8TDD5 MCOLN3 PTHR12127:SF5 MUCOLIPIN MUCOLIPIN-3 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=5122|UniProtKB=Q9NYD6 Q9NYD6 HOXC10 PTHR45874:SF2 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN HOX-C10 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=25791|UniProtKB=Q8IXW5 Q8IXW5 RPAP2 PTHR14732:SF0 UNCHARACTERIZED RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;dephosphorylation#GO:0016311;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=8672|UniProtKB=Q9UN73 Q9UN73 PCDHA6 PTHR24028:SF305 CADHERIN-87A PROTOCADHERIN ALPHA-6-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=14965|UniProtKB=Q9BY71 Q9BY71 LRRC3 PTHR24369:SF8 ANTIGEN BSP, PUTATIVE-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 3-RELATED HUMAN|HGNC=30630|UniProtKB=Q96A44 Q96A44 SPSB4 PTHR12245:SF3 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=16137|UniProtKB=Q9BQM9 Q9BQM9 C20orf144 PTHR37335:SF1 RIKEN CDNA 1700003F12 GENE RIKEN CDNA 1700003F12 GENE HUMAN|HGNC=11453|UniProtKB=P50225 P50225 SULT1A1 PTHR11783:SF156 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1A1 transferase#PC00220 HUMAN|HGNC=2459|UniProtKB=P19784 P19784 CSNK2A2 PTHR24054:SF34 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA' transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of chromosome segregation#GO:0051983;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;chromosome segregation#GO:0007059;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;chromosome separation#GO:0051304;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;peptidyl-threonine phosphorylation#GO:0018107;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;peptidyl-serine modification#GO:0018209;cell cycle#GO:0007049 cytoplasm#GO:0005737;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 HUMAN|HGNC=6776|UniProtKB=O75444 O75444 MAF PTHR10129:SF9 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAF cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=5144|UniProtKB=P84074 P84074 HPCA PTHR23055:SF57 CALCIUM BINDING PROTEINS NEURON-SPECIFIC CALCIUM-BINDING PROTEIN HIPPOCALCIN HUMAN|HGNC=19193|UniProtKB=Q86U17 Q86U17 SERPINA11 PTHR11461:SF154 SERINE PROTEASE INHIBITOR, SERPIN SERPIN A11 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|Gene=YD021_HUMAN|UniProtKB=A8MVM7 A8MVM7 - PTHR14931:SF1 GENE 340-RELATED SUBFAMILY NOT NAMED HUMAN|HGNC=30313|UniProtKB=Q5T4S7 Q5T4S7 UBR4 PTHR21725:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR4 E3 UBIQUITIN-PROTEIN LIGASE UBR4 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=6486|UniProtKB=P07942 P07942 LAMB1 PTHR10574:SF233 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-1 integrin binding#GO:0005178;structural molecule activity#GO:0005198;binding#GO:0005488;extracellular matrix structural constituent#GO:0005201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cell morphogenesis involved in differentiation#GO:0000904;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;substrate adhesion-dependent cell spreading#GO:0034446;localization of cell#GO:0051674;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;extracellular matrix organization#GO:0030198;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;cell differentiation#GO:0030154;extracellular structure organization#GO:0043062;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;cell migration#GO:0016477;locomotion#GO:0040011 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=18531|UniProtKB=Q96NW7 Q96NW7 LRRC7 PTHR23119:SF48 DISCS LARGE LEUCINE-RICH REPEAT-CONTAINING PROTEIN 7 endosomal transport#GO:0016197;establishment or maintenance of cell polarity#GO:0007163;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;developmental process#GO:0032502;biological adhesion#GO:0022610;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to organelle#GO:0033365;protein localization to plasma membrane#GO:0072659;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;retrograde transport, endosome to plasma membrane#GO:1990126;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;anchoring junction#GO:0070161;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;ionotropic glutamate receptor complex#GO:0008328;adherens junction#GO:0005912;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26355|UniProtKB=Q6PF05 Q6PF05 TTC23L PTHR14485:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 23 TETRATRICOPEPTIDE REPEAT PROTEIN 23-LIKE HUMAN|HGNC=25158|UniProtKB=Q96ER3 Q96ER3 SAAL1 PTHR23424:SF23 SERUM AMYLOID A PROTEIN SAAL1 apolipoprotein#PC00052 HUMAN|HGNC=24567|UniProtKB=Q9BWH6 Q9BWH6 RPAP1 PTHR21483:SF18 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=14353|UniProtKB=O14645 O14645 DNALI1 PTHR13183:SF0 AXONEMAL INNER ARM DYNEIN LIGHT CHAIN 28 AXONEMAL DYNEIN LIGHT INTERMEDIATE POLYPEPTIDE 1 dynein heavy chain binding#GO:0045504;protein binding#GO:0005515;binding#GO:0005488 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=9080|UniProtKB=P26678 P26678 PLN PTHR21194:SF1 CARDIAC PHOSPHOLAMBAN CARDIAC PHOSPHOLAMBAN HUMAN|HGNC=27106|UniProtKB=Q6P988 Q6P988 NOTUM PTHR21562:SF7 NOTUM-RELATED PALMITOLEOYL-PROTEIN CARBOXYLESTERASE NOTUM hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;cellular protein modification process#GO:0006464;macromolecule deacylation#GO:0098732;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;protein deacylation#GO:0035601;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;lipoprotein metabolic process#GO:0042157;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178 HUMAN|HGNC=12766|UniProtKB=O96028 O96028 NSD2 PTHR22884:SF293 SET DOMAIN PROTEINS HISTONE-LYSINE N-METHYLTRANSFERASE NSD2 N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=19018|UniProtKB=Q9H8W5 Q9H8W5 TRIM45 PTHR25462:SF291 BONUS, ISOFORM C-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 45 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=9951|UniProtKB=P05451 P05451 REG1A PTHR22803:SF131 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED LITHOSTATHINE-1-ALPHA carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 response to organic substance#GO:0010033;response to external biotic stimulus#GO:0043207;response to oxygen-containing compound#GO:1901700;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;response to peptide hormone#GO:0043434;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;positive regulation of cell population proliferation#GO:0008284;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to organonitrogen compound#GO:0010243;cell population proliferation#GO:0008283;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607;response to chemical#GO:0042221;response to peptide#GO:1901652;antimicrobial humoral response#GO:0019730;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 CCKR signaling map#P06959>REG1A#G07269;CCKR signaling map#P06959>REG1A#G06976 HUMAN|HGNC=8213|UniProtKB=Q8NH94 Q8NH94 OR1L1 PTHR48001:SF51 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1L1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=9020|UniProtKB=P30613 P30613 PKLR PTHR11817:SF31 PYRUVATE KINASE PYRUVATE KINASE PKLR carbon-oxygen lyase activity#GO:0016835;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydro-lyase activity#GO:0016836;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;lyase activity#GO:0016829;isomerase activity#GO:0016853;oxidoreductase activity#GO:0016491;kinase activity#GO:0016301 purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;cellular response to hormone stimulus#GO:0032870;ATP metabolic process#GO:0046034;ATP generation from ADP#GO:0006757;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;oxoacid metabolic process#GO:0043436;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;cellular response to organonitrogen compound#GO:0071417;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;ADP metabolic process#GO:0046031;organonitrogen compound metabolic process#GO:1901564;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132;Glycolysis#P00024>Pyruvate kinase#P00675 HUMAN|HGNC=30378|UniProtKB=O60645 O60645 EXOC3 PTHR21292:SF13 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;vesicle organization#GO:0016050;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 membrane traffic protein#PC00150 HUMAN|HGNC=32418|UniProtKB=Q99666 Q99666 RGPD6 PTHR23138:SF87 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26759|UniProtKB=Q8N9A8 Q8N9A8 CNEP1R1 PTHR20996:SF2 UNCHARACTERIZED NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 HUMAN|HGNC=29035|UniProtKB=O43314 O43314 PPIP5K2 PTHR12750:SF10 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;cellular carbohydrate metabolic process#GO:0044262;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotide kinase#PC00172 HUMAN|HGNC=28860|UniProtKB=Q9H2J4 Q9H2J4 PDCL3 PTHR45809:SF4 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 3 viral or transposable element protein#PC00237 HUMAN|HGNC=15920|UniProtKB=Q9Y6I8 Q9Y6I8 PXMP4 PTHR15460:SF3 PEROXISOMAL MEMBRANE PROTEIN 4 PEROXISOMAL MEMBRANE PROTEIN 4 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;microbody membrane#GO:0031903;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 HUMAN|HGNC=13070|UniProtKB=Q9NRM2 Q9NRM2 ZNF277 PTHR13267:SF3 ZINC FINGER PROTEIN 277 ZINC FINGER PROTEIN 277 zinc finger transcription factor#PC00244 HUMAN|HGNC=15916|UniProtKB=Q9P286 Q9P286 PAK5 PTHR48015:SF27 SERINE/THREONINE-PROTEIN KINASE TAO SERINE/THREONINE-PROTEIN KINASE PAK 5 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517 HUMAN|HGNC=25221|UniProtKB=Q9H3L0 Q9H3L0 MMADHC PTHR13192:SF3 MY011 PROTEIN COBALAMIN TRAFFICKING PROTEIN CBLD cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18873|UniProtKB=Q9BYX4 Q9BYX4 IFIH1 PTHR14074:SF14 HELICASE WITH DEATH DOMAIN-RELATED INTERFERON-INDUCED HELICASE C DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;zinc ion binding#GO:0008270;binding#GO:0005488;organic cyclic compound binding#GO:0097159;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;double-stranded RNA binding#GO:0003725 response to virus#GO:0009615;positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;positive regulation of metabolic process#GO:0009893;innate immune response#GO:0045087;positive regulation of cytokine production#GO:0001819;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;positive regulation of macromolecule metabolic process#GO:0010604;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9580|UniProtKB=O43586 O43586 PSTPIP1 PTHR23065:SF51 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;protein-containing complex subunit organization#GO:0043933 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=9763|UniProtKB=P61019 P61019 RAB2A PTHR47979:SF12 DRAB11-RELATED RAS-RELATED PROTEIN RAB-2A bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=30758|UniProtKB=Q8NDF8 Q8NDF8 TENT4B PTHR23092:SF51 POLY(A) RNA POLYMERASE TERMINAL NUCLEOTIDYLTRANSFERASE 4B adenylyltransferase activity#GO:0070566;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=8177|UniProtKB=P0DN82 P0DN82 OR12D1 PTHR26451:SF968 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 12D1 HUMAN|HGNC=32159|UniProtKB=Q9BT17 Q9BT17 MTG1 PTHR45782:SF4 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 HUMAN|HGNC=13811|UniProtKB=Q6U841 Q6U841 SLC4A10 PTHR11453:SF32 ANION EXCHANGE PROTEIN SODIUM-DRIVEN CHLORIDE BICARBONATE EXCHANGER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=315|UniProtKB=Q9Y4W6 Q9Y4W6 AFG3L2 PTHR43655:SF9 ATP-DEPENDENT PROTEASE AFG3-LIKE PROTEIN 2 mitochondrial fusion#GO:0008053;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;mitochondrial protein processing#GO:0034982;membrane organization#GO:0061024;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cristae formation#GO:0042407;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;protein processing#GO:0016485;inner mitochondrial membrane organization#GO:0007007;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 metalloprotease#PC00153 HUMAN|HGNC=7328|UniProtKB=O43196 O43196 MSH5 PTHR11361:SF142 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER MUTS PROTEIN HOMOLOG 5 mismatched DNA binding#GO:0030983;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;double-stranded DNA binding#GO:0003690;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;intracellular#GO:0005622;DNA repair complex#GO:1990391 DNA metabolism protein#PC00009 HUMAN|HGNC=7181|UniProtKB=P51948 P51948 MNAT1 PTHR12683:SF13 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 DNA repair#GO:0006281;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;regulation of phosphate metabolic process#GO:0019220;regulation of cyclin-dependent protein kinase activity#GO:1904029;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;nucleic acid-templated transcription#GO:0097659;regulation of protein kinase activity#GO:0045859;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;regulation of transferase activity#GO:0051338;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675 chaperone#PC00072 HUMAN|HGNC=29801|UniProtKB=Q7L9L4 Q7L9L4 MOB1B PTHR22599:SF63 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 1B kinase activator#PC00138 HUMAN|HGNC=2220|UniProtKB=Q9Y6Z7 Q9Y6Z7 COLEC10 PTHR24024:SF20 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A COLLECTIN-10 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 surfactant#PC00212 HUMAN|HGNC=26776|UniProtKB=Q6PIY7 Q6PIY7 TENT2 PTHR12271:SF40 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE GLD2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 HUMAN|HGNC=30764|UniProtKB=Q9BWF2 Q9BWF2 TRAIP PTHR46569:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRAIP E3 UBIQUITIN-PROTEIN LIGASE TRAIP ubiquitin-protein ligase#PC00234 HUMAN|HGNC=8539|UniProtKB=P47900 P47900 P2RY1 PTHR24231:SF2 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 1 G-protein coupled receptor#PC00021 HUMAN|HGNC=18232|UniProtKB=Q5W0U4 Q5W0U4 BSPRY PTHR24103:SF568 E3 UBIQUITIN-PROTEIN LIGASE TRIM B BOX AND SPRY DOMAIN-CONTAINING PROTEIN ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=15853|UniProtKB=Q9Y6D5 Q9Y6D5 ARFGEF2 PTHR10663:SF124 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 2 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=28897|UniProtKB=Q9H7C4 Q9H7C4 SYNC PTHR47147:SF1 SYNCOILIN SYNCOILIN HUMAN|HGNC=23174|UniProtKB=Q7Z5L7 Q7Z5L7 PODN PTHR45712:SF20 AGAP008170-PA PODOCAN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=7708|UniProtKB=O75306 O75306 NDUFS2 PTHR11993:SF10 NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 HUMAN|HGNC=9683|UniProtKB=Q92729 Q92729 PTPRU PTHR19134:SF207 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE U hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=11700|UniProtKB=Q13569 Q13569 TDG PTHR12159:SF9 G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE G/T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE DNA glycosylase#PC00010 HUMAN|HGNC=13437|UniProtKB=Q9UHP6 Q9UHP6 RSPH14 PTHR15599:SF1 RTDR1 RADIAL SPOKE HEAD 14 HOMOLOG HUMAN|HGNC=19392|UniProtKB=Q8WXH5 Q8WXH5 SOCS4 PTHR10155:SF21 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phosphorylation#GO:0016310;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879 HUMAN|HGNC=10872|UniProtKB=Q9UNP4 Q9UNP4 ST3GAL5 PTHR13713:SF60 SIALYLTRANSFERASE LACTOSYLCERAMIDE ALPHA-2,3-SIALYLTRANSFERASE transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=24012|UniProtKB=Q9BRS8 Q9BRS8 LARP6 PTHR22792:SF71 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 6 RNA metabolism protein#PC00031 HUMAN|HGNC=1852|UniProtKB=P07199 P07199 CENPB PTHR19303:SF25 TRANSPOSON MAJOR CENTROMERE AUTOANTIGEN B nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 HUMAN|HGNC=4481|UniProtKB=Q8NDV2 Q8NDV2 GPR26 PTHR24245:SF6 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 26 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 G-protein coupled receptor#PC00021 HUMAN|HGNC=16013|UniProtKB=Q9Y575 Q9Y575 ASB3 PTHR24178:SF30 MOLTING PROTEIN MLT-4 ANKYRIN REPEAT AND SOCS BOX PROTEIN 3 protein localization to plasma membrane#GO:0072659;blood circulation#GO:0008015;cellular localization#GO:0051641;regulation of multicellular organismal process#GO:0051239;regulation of muscle contraction#GO:0006937;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;regulation of heart contraction#GO:0008016;system process#GO:0003008;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;regulation of system process#GO:0044057;cellular process#GO:0009987;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;protein localization to cell periphery#GO:1990778;cellular macromolecule localization#GO:0070727;protein localization to cilium#GO:0061512;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;protein localization to organelle#GO:0033365;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990;sarcolemma#GO:0042383;plasma membrane#GO:0005886 HUMAN|HGNC=4890|UniProtKB=P36980 P36980 CFHR2 PTHR45785:SF12 COMPLEMENT FACTOR H-RELATED COMPLEMENT FACTOR H-RELATED PROTEIN 1-RELATED HUMAN|HGNC=25592|UniProtKB=Q9NV88 Q9NV88 INTS9 PTHR46094:SF1 INTEGRATOR COMPLEX SUBUNIT 9 INTEGRATOR COMPLEX SUBUNIT 9 HUMAN|HGNC=12862|UniProtKB=P26651 P26651 ZFP36 PTHR12547:SF58 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36 RNA metabolism protein#PC00031 HUMAN|HGNC=6206|UniProtKB=P17535 P17535 JUND PTHR11462:SF7 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JUN-D cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic leucine zipper transcription factor#PC00056 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838;Gonadotropin-releasing hormone receptor pathway#P06664>Jund#P06764 HUMAN|HGNC=23369|UniProtKB=Q49AS3 Q49AS3 LRRC37A5P PTHR23045:SF9 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37B-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=6492|UniProtKB=P11047 P11047 LAMC1 PTHR10574:SF270 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;tissue development#GO:0009888 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=15021|UniProtKB=Q7Z3T1 Q7Z3T1 OR2W3 PTHR26453:SF223 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2W3 transmembrane signal receptor#PC00197 HUMAN|HGNC=3819|UniProtKB=Q12778 Q12778 FOXO1 PTHR45767:SF1 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 CCKR signaling map#P06959>FOXO1#P07167;PI3 kinase pathway#P00048>FOXO#P01198;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>FKHR#P00898 HUMAN|HGNC=6051|UniProtKB=O14732 O14732 IMPA2 PTHR20854:SF29 INOSITOL MONOPHOSPHATASE INOSITOL MONOPHOSPHATASE 2 inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;signaling#GO:0023052;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 phosphatase#PC00181 HUMAN|HGNC=5926|UniProtKB=A0A0A0MRZ9 A0A0A0MRZ9 IGLV5-52 PTHR23267:SF463 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 5-52 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=28027|UniProtKB=O95876 O95876 WDPCP PTHR13667:SF5 HOMOLOC-13 WD REPEAT-CONTAINING AND PLANAR CELL POLARITY EFFECTOR PROTEIN FRITZ HOMOLOG cilium organization#GO:0044782;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;establishment of localization#GO:0051234;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=14282|UniProtKB=Q9H1B7 Q9H1B7 IRF2BPL PTHR10816:SF14 MYELIN TRANSCRIPTION FACTOR 1-RELATED E3 UBIQUITIN-PROTEIN LIGASE IRF2BPL-RELATED transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;transcription corepressor activity#GO:0003714 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=21075|UniProtKB=Q86VY9 Q86VY9 TMEM200A PTHR31815:SF0 AGAP005329-PA TRANSMEMBRANE PROTEIN 200A HUMAN|HGNC=18479|UniProtKB=Q9UHA3 Q9UHA3 RSL24D1 PTHR10792:SF26 60S RIBOSOMAL PROTEIN L24 RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=18894|UniProtKB=Q8WTR2 Q8WTR2 DUSP19 PTHR46377:SF1 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=32404|UniProtKB=A6NM11 A6NM11 LRRC37A2 PTHR23045:SF11 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=1548|UniProtKB=P16152 P16152 CBR1 PTHR43963:SF2 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE [NADPH] 1 reductase#PC00198 HUMAN|HGNC=3265|UniProtKB=P05198 P05198 EIF2S1 PTHR10602:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 translation initiation factor#PC00224 Apoptosis signaling pathway#P00006>ELF2alpha#P00307 HUMAN|HGNC=1674|UniProtKB=P07766 P07766 CD3E PTHR10570:SF9 T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;lymphocyte activation#GO:0046649;immune system development#GO:0002520;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;hematopoietic or lymphoid organ development#GO:0048534;cell communication#GO:0007154;cellular process#GO:0009987;T cell differentiation#GO:0030217;cell activation#GO:0001775;regulation of biological process#GO:0050789;immune system process#GO:0002376;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;lymphocyte differentiation#GO:0030098;T cell activation#GO:0042110;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;signaling#GO:0023052;leukocyte activation#GO:0045321 receptor complex#GO:0043235;membrane protein complex#GO:0098796;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 T cell activation#P00053>CD3 eta#P01302 HUMAN|HGNC=18703|UniProtKB=Q9NVQ4 Q9NVQ4 FAIM PTHR13088:SF3 FAS APOPTOTIC INHIBITORY MOLECULE FAIM FAS APOPTOTIC INHIBITORY MOLECULE 1 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of apoptotic signaling pathway#GO:2001233;nucleobase-containing compound metabolic process#GO:0006139;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;I-kappaB kinase/NF-kappaB signaling#GO:0007249;negative regulation of apoptotic signaling pathway#GO:2001234;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;negative regulation of programmed cell death#GO:0043069;cellular nitrogen compound biosynthetic process#GO:0044271;cell death#GO:0008219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of DNA-binding transcription factor activity#GO:0051090;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of apoptotic process#GO:0043066;positive regulation of developmental process#GO:0051094;positive regulation of DNA-binding transcription factor activity#GO:0051091;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;regulation of cellular macromolecule biosynthetic process#GO:2000112 HUMAN|HGNC=1556|UniProtKB=O95503 O95503 CBX6 PTHR19277:SF94 PENTRAXIN CHROMOBOX PROTEIN HOMOLOG 6-RELATED HUMAN|HGNC=2763|UniProtKB=P12838 P12838 DEFA4 PTHR11876:SF23 ALPHA-DEFENSIN 1 NEUTROPHIL DEFENSIN 4 response to external biotic stimulus#GO:0043207;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;antibacterial humoral response#GO:0019731;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;innate immune response#GO:0045087;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cellular response to biotic stimulus#GO:0071216;cellular process#GO:0009987;defense response to Gram-positive bacterium#GO:0050830;response to lipopolysaccharide#GO:0032496;defense response to Gram-negative bacterium#GO:0050829;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=3658|UniProtKB=Q9UGM5 Q9UGM5 FETUB PTHR13814:SF10 FETUIN FETUIN-B peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of endopeptidase activity#GO:0010951;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=6594|UniProtKB=P50458 P50458 LHX2 PTHR24208:SF80 LIM/HOMEOBOX PROTEIN LHX LIM/HOMEOBOX PROTEIN LHX2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>LHX2#P06756 HUMAN|HGNC=11641|UniProtKB=Q9NQB0 Q9NQB0 TCF7L2 PTHR10373:SF32 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7-LIKE 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 Angiogenesis#P00005>TCF#P00242;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Cadherin signaling pathway#P00012>TCF/LEF#P00465 HUMAN|HGNC=10297|UniProtKB=P49247 P49247 RPIA PTHR11934:SF0 RIBOSE-5-PHOSPHATE ISOMERASE RIBOSE-5-PHOSPHATE ISOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;glucose 6-phosphate metabolic process#GO:0051156;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;oxidation-reduction process#GO:0055114;organophosphate metabolic process#GO:0019637;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 isomerase#PC00135 Pentose phosphate pathway#P02762>Ribulose 5-P Isomerase#P03071 HUMAN|HGNC=7436|UniProtKB=P42898 P42898 MTHFR PTHR45754:SF3 METHYLENETETRAHYDROFOLATE REDUCTASE METHYLENETETRAHYDROFOLATE REDUCTASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;sulfur compound metabolic process#GO:0006790;pteridine-containing compound metabolic process#GO:0042558;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;aspartate family amino acid biosynthetic process#GO:0009067;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=23197|UniProtKB=Q9NQW1 Q9NQW1 SEC31B PTHR13923:SF22 SEC31-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC31B endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;Golgi vesicle budding#GO:0048194;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;COPII-coated vesicle budding#GO:0090114;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=3091|UniProtKB=Q13627 Q13627 DYRK1A PTHR24058:SF121 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;molecular function regulator#GO:0098772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;peptidyl-threonine phosphorylation#GO:0018107;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10017|UniProtKB=Q99578 Q99578 RIT2 PTHR24070:SF203 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RIT2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168 neurogenesis#GO:0022008;cell projection organization#GO:0030030;positive regulation of cell projection organization#GO:0031346;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;neuron differentiation#GO:0030182;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of neuron differentiation#GO:0045666;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;regulation of neuron differentiation#GO:0045664;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;multicellular organismal process#GO:0032501;neuron development#GO:0048666;positive regulation of neuron projection development#GO:0010976;generation of neurons#GO:0048699;positive regulation of multicellular organismal process#GO:0051240 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=15027|UniProtKB=Q8NGZ6 Q8NGZ6 OR6F1 PTHR26454:SF12 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6F1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=23575|UniProtKB=O75179 O75179 ANKRD17 PTHR23206:SF1 MASK PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 17 response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;immune response#GO:0006955;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;defense response#GO:0006952 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 defense/immunity protein#PC00090 HUMAN|HGNC=4929|UniProtKB=P10073 P10073 ZSCAN22 PTHR23226:SF59 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 22 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=616|UniProtKB=P02749 P02749 APOH PTHR19325:SF549 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING BETA-2-GLYCOPROTEIN 1 HUMAN|HGNC=6220|UniProtKB=P16389 P16389 KCNA2 PTHR11537:SF23 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;ion transport#GO:0006811;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;somatodendritic compartment#GO:0036477;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;ion channel complex#GO:0034702;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;distal axon#GO:0150034;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=20660|UniProtKB=Q96SJ8 Q96SJ8 TSPAN18 PTHR19282:SF249 TETRASPANIN TETRASPANIN-18 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=16891|UniProtKB=Q96RU8 Q96RU8 TRIB1 PTHR22961:SF17 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;regulation of intracellular signal transduction#GO:1902531;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;intracellular signal transduction#GO:0035556;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;positive regulation of proteasomal protein catabolic process#GO:1901800;organonitrogen compound catabolic process#GO:1901565;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;catabolic process#GO:0009056;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;signaling#GO:0023052;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of transferase activity#GO:0051338;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|Gene=YJ013_HUMAN|UniProtKB=Q6ZQT7 Q6ZQT7 - PTHR37553:SF7 FAMILY NOT NAMED SUBFAMILY NOT NAMED HUMAN|HGNC=4388|UniProtKB=P38405 P38405 GNAL PTHR10218:SF233 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(OLF) SUBUNIT ALPHA pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of adenylate cyclase activity#GO:0045761;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;dopamine receptor signaling pathway#GO:0007212;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;trans-synaptic signaling#GO:0099537;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;nervous system process#GO:0050877;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117 5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Endothelin signaling pathway#P00019>Gs#P00584;Enkephalin release#P05913>G-Protein (s)#P05977;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gsalpha#P00705 HUMAN|HGNC=16775|UniProtKB=Q9BYU5 Q9BYU5 KRTAP2-1 PTHR23262:SF7 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 2-1 HUMAN|HGNC=26166|UniProtKB=Q6ZN55 Q6ZN55 ZNF574 PTHR24376:SF69 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 574 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=740|UniProtKB=Q9NQ33 Q9NQ33 ASCL3 PTHR13935:SF68 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=18423|UniProtKB=O75140 O75140 DEPDC5 PTHR13179:SF8 DEP DOMAIN CONTAINING PROTEIN 5 GATOR COMPLEX PROTEIN DEPDC5 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;cellular response to starvation#GO:0009267;regulation of signal transduction#GO:0009966;catabolic process#GO:0009056;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;regulation of autophagy#GO:0010506;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cell communication#GO:0007154;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991 GTPase-activating protein#PC00257 HUMAN|HGNC=23303|UniProtKB=Q8NG11 Q8NG11 TSPAN14 PTHR19282:SF261 TETRASPANIN TETRASPANIN-14 protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=24758|UniProtKB=Q5BKX5 Q5BKX5 C19orf54 PTHR28631:SF1 UPF0692 PROTEIN C19ORF54 UPF0692 PROTEIN C19ORF54 HUMAN|HGNC=30027|UniProtKB=Q6IE81 Q6IE81 JADE1 PTHR13793:SF79 PHD FINGER PROTEINS PROTEIN JADE-1 histone H3 acetylation#GO:0043966;peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;histone H4 acetylation#GO:0043967;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 zinc finger transcription factor#PC00244 HUMAN|HGNC=26372|UniProtKB=Q8N0W7 Q8N0W7 FMR1NB PTHR37360:SF1 FRAGILE X MENTAL RETARDATION 1 NEIGHBOR PROTEIN FRAGILE X MENTAL RETARDATION 1 NEIGHBOR PROTEIN HUMAN|HGNC=6440|UniProtKB=P12035 P12035 KRT3 PTHR45616:SF38 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 3 HUMAN|HGNC=14052|UniProtKB=P49406 P49406 MRPL19 PTHR15680:SF9 RIBOSOMAL PROTEIN L19 39S RIBOSOMAL PROTEIN L19, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202 HUMAN|HGNC=24756|UniProtKB=Q6ZP01 Q6ZP01 RBM44 PTHR48026:SF8 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN RNA-BINDING PROTEIN 44 HUMAN|HGNC=20809|UniProtKB=Q8TF32 Q8TF32 ZNF431 PTHR24384:SF88 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 431 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=13964|UniProtKB=Q8NHA8 Q8NHA8 OR1F12 PTHR48001:SF69 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1F12 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=12203|UniProtKB=A0A075B6N3 A0A075B6N3 TRBV24-1 PTHR23268:SF54 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 24-1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=16804|UniProtKB=O00308 O00308 WWP2 PTHR11254:SF396 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE NEDD4-LIKE E3 UBIQUITIN-PROTEIN LIGASE WWP2 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;regulation of transmembrane transport#GO:0034762;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;ion transmembrane transport#GO:0034220;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of ion transmembrane transport#GO:0034765;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;aromatic compound biosynthetic process#GO:0019438;regulation of ion transport#GO:0043269;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;transport#GO:0006810;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;transmembrane transport#GO:0055085;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of protein metabolic process#GO:0051247;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;protein K63-linked ubiquitination#GO:0070534 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 HUMAN|HGNC=16943|UniProtKB=Q9UKI2 Q9UKI2 CDC42EP3 PTHR15344:SF3 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 3 HUMAN|HGNC=31974|UniProtKB=A8MUH7 A8MUH7 PDZK1P1 PTHR14191:SF6 PDZ DOMAIN CONTAINING PROTEIN NA(+)/H(+) EXCHANGE REGULATORY COFACTOR NHE-RF3-RELATED molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 HUMAN|HGNC=2442|UniProtKB=Q14406 Q14406 CSHL1 PTHR11417:SF67 SOMATOTROPIN,PROLACTIN CHORIONIC SOMATOMAMMOTROPIN HORMONE 1-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;response to extracellular stimulus#GO:0009991;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to hormone stimulus#GO:0032870;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of receptor signaling pathway via STAT#GO:1904894;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of growth#GO:0045927;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;tyrosine phosphorylation of STAT protein#GO:0007260;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to peptide hormone#GO:0043434;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;growth#GO:0040007;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of growth#GO:0040008;regulation of receptor signaling pathway via STAT#GO:1904892;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;response to nutrient levels#GO:0031667;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to hormone#GO:0009725;receptor signaling pathway via STAT#GO:0097696;peptidyl-tyrosine modification#GO:0018212;regulation of macromolecule metabolic process#GO:0060255;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 HUMAN|HGNC=1075|UniProtKB=P34820 P34820 BMP8B PTHR11848:SF119 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 8A-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=33867|UniProtKB=A6NFY7 A6NFY7 SDHAF1 PTHR47046:SF1 SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex II assembly#GO:0034553;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=10291|UniProtKB=P35244 P35244 RPA3 PTHR15114:SF1 REPLICATION PROTEIN A3 REPLICATION PROTEIN A 14 KDA SUBUNIT damaged DNA binding#GO:0003684;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;mismatch repair#GO:0006298;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;base-excision repair#GO:0006284;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 pre-replicative complex#GO:0036387;intracellular membrane-bounded organelle#GO:0043231;epsilon DNA polymerase complex#GO:0008622;replisome#GO:0030894;MCM complex#GO:0042555;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;replication fork#GO:0005657;membrane-enclosed lumen#GO:0031974;origin recognition complex#GO:0000808;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;DNA replication preinitiation complex#GO:0031261;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;CMG complex#GO:0071162;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 Cell cycle#P00013>Pre-replication Complex#P00478 HUMAN|HGNC=25633|UniProtKB=Q7Z5S9 Q7Z5S9 TMEM144 PTHR16119:SF17 TRANSMEMBRANE PROTEIN 144 TRANSMEMBRANE PROTEIN 144 HUMAN|HGNC=9804|UniProtKB=Q9H0H5 Q9H0H5 RACGAP1 PTHR46199:SF1 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 GTPase-activating protein#PC00257 HUMAN|HGNC=790|UniProtKB=Q9Y2D1 Q9Y2D1 ATF5 PTHR13044:SF3 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-5 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=17358|UniProtKB=Q9H3S4 Q9H3S4 TPK1 PTHR13622:SF8 THIAMIN PYROPHOSPHOKINASE THIAMIN PYROPHOSPHOKINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 Thiamin metabolism#P02780>Thiamine kinase#P03176 HUMAN|HGNC=30232|UniProtKB=Q7Z422 Q7Z422 SZRD1 PTHR31796:SF4 SUZ DOMAIN-CONTAINING PROTEIN 1 SUZ DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=11021|UniProtKB=P78382 P78382 SLC35A1 PTHR10231:SF66 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER CMP-SIALIC ACID TRANSPORTER carbohydrate derivative transmembrane transporter activity#GO:1901505;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;UDP-galactose transmembrane transporter activity#GO:0005459;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;nucleobase-containing compound transmembrane transporter activity#GO:0015932;ion transmembrane transporter activity#GO:0015075;pyrimidine nucleotide-sugar transmembrane transporter activity#GO:0015165;nucleotide-sugar transmembrane transporter activity#GO:0005338;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=20303|UniProtKB=Q8IWU4 Q8IWU4 SLC30A8 PTHR11562:SF37 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER ZINC TRANSPORTER 8 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;hormone secretion#GO:0046879;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;secretion#GO:0046903;divalent inorganic cation transport#GO:0072511;insulin secretion#GO:0030073;transition metal ion transport#GO:0000041;hormone transport#GO:0009914;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;response to oxygen-containing compound#GO:1901700;transition metal ion homeostasis#GO:0055076;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cellular localization#GO:0060341;peptide transport#GO:0015833;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;protein transport#GO:0015031;metal ion homeostasis#GO:0055065;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;cellular metal ion homeostasis#GO:0006875;macromolecule localization#GO:0033036;transport#GO:0006810;peptide secretion#GO:0002790;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;amide transport#GO:0042886;organic substance transport#GO:0071702;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;peptide hormone secretion#GO:0030072;signal release#GO:0023061;cellular divalent inorganic cation homeostasis#GO:0072503;signaling#GO:0023052;cell-cell signaling#GO:0007267;secretion by cell#GO:0032940;response to organic substance#GO:0010033;cellular transition metal ion homeostasis#GO:0046916;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;response to metal ion#GO:0010038;homeostatic process#GO:0042592;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;chemical homeostasis#GO:0048878;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to chemical#GO:0042221;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;cellular zinc ion homeostasis#GO:0006882 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=28711|UniProtKB=Q5T9C9 Q5T9C9 PIP5KL1 PTHR23086:SF46 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE-LIKE PROTEIN 1 kinase#PC00137 HUMAN|HGNC=12472|UniProtKB=P49459 P49459 UBE2A PTHR24067:SF243 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 A ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;histone ubiquitination#GO:0016574;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;covalent chromatin modification#GO:0016569;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular protein catabolic process#GO:0044257;chromatin organization#GO:0006325;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=53923|UniProtKB=P0DPK3 P0DPK3 NOTCH2NLB PTHR24033:SF151 EGF-LIKE DOMAIN-CONTAINING PROTEIN NOTCH HOMOLOG 2 N-TERMINAL-LIKE PROTEIN B HUMAN|HGNC=29188|UniProtKB=Q08AD1 Q08AD1 CAMSAP2 PTHR21595:SF1 UNCHARACTERIZED CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;negative regulation of biological process#GO:0048519;protein-containing complex disassembly#GO:0032984;cellular protein complex disassembly#GO:0043624;regulation of organelle organization#GO:0033043;microtubule depolymerization#GO:0007019;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 HUMAN|HGNC=33862|UniProtKB=A6NFK2 A6NFK2 GRXCR2 PTHR46926:SF1 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 2 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 2 oxidoreductase#PC00176 HUMAN|HGNC=26059|UniProtKB=Q9NWV4 Q9NWV4 CZIB PTHR12857:SF0 UNCHARACTERIZED CXXC MOTIF CONTAINING ZINC BINDING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 HUMAN|HGNC=4163|UniProtKB=P22102 P22102 GART PTHR10520:SF12 TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pigment biosynthetic process#GO:0046148;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;pigment metabolic process#GO:0042440;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;purine nucleobase biosynthetic process#GO:0009113;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 De novo purine biosynthesis#P02738>Phosphoribosylamine glycine ligase#P02908 HUMAN|HGNC=29572|UniProtKB=Q86X29 Q86X29 LSR PTHR15923:SF1 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN LIPOLYSIS-STIMULATED LIPOPROTEIN RECEPTOR immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=24840|UniProtKB=Q9UBC7 Q9UBC7 GALP PTHR20950:SF1 GALANIN-RELATED PEPTIDE GALANIN-LIKE PEPTIDE response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;defense response to Gram-negative bacterium#GO:0050829;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;antimicrobial humoral response#GO:0019730;defense response to other organism#GO:0098542;response to other organism#GO:0051707;response to starvation#GO:0042594;defense response#GO:0006952 HUMAN|HGNC=16714|UniProtKB=Q96KN3 Q96KN3 PKNOX2 PTHR11850:SF53 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN PKNOX2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=8281|UniProtKB=Q9Y3N9 Q9Y3N9 OR2W1 PTHR26453:SF169 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2W1 transmembrane signal receptor#PC00197 HUMAN|HGNC=10458|UniProtKB=Q92681 Q92681 RSC1A1 PTHR15397:SF2 SODIUM-GLUCOSE COTRANSPORTER REGULATORY PROTEIN -RELATED REGULATORY SOLUTE CARRIER PROTEIN FAMILY 1 MEMBER 1 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=32037|UniProtKB=Q5VUY0 Q5VUY0 AADACL3 PTHR23024:SF115 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE-LIKE 3 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 deacetylase#PC00087 HUMAN|HGNC=8041|UniProtKB=P53384 P53384 NUBP1 PTHR23264:SF35 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1 metal cluster binding#GO:0051540;iron-sulfur cluster binding#GO:0051536;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=16508|UniProtKB=Q96QF0 Q96QF0 RAB3IP PTHR14430:SF2 RABIN3-RELATED RAB-3A-INTERACTING PROTEIN Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=2902|UniProtKB=Q92796 Q92796 DLG3 PTHR23119:SF28 DISCS LARGE DISKS LARGE HOMOLOG 3 establishment or maintenance of cell polarity#GO:0007163;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;developmental process#GO:0032502;biological adhesion#GO:0022610;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;signaling#GO:0023052;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;multicellular organismal process#GO:0032501;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;neuromuscular junction#GO:0031594;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;basolateral plasma membrane#GO:0016323;ion channel complex#GO:0034702;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=12765|UniProtKB=O15353 O15353 FOXN1 PTHR46721:SF1 FORKHEAD BOX PROTEIN N1 FORKHEAD BOX PROTEIN N1 HUMAN|HGNC=14488|UniProtKB=Q9BQ48 Q9BQ48 MRPL34 PTHR14503:SF4 MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER 39S RIBOSOMAL PROTEIN L34, MITOCHONDRIAL ribosomal protein#PC00202 HUMAN|HGNC=15626|UniProtKB=P31995 P31995 FCGR2C PTHR11481:SF97 IMMUNOGLOBULIN FC RECEPTOR LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR II-A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=33160|UniProtKB=P0C7L1 P0C7L1 SPINK8 PTHR21312:SF37 SERINE PROTEASE INHIBITOR SERINE PROTEASE INHIBITOR KAZAL-TYPE 8 protease inhibitor#PC00191 HUMAN|HGNC=37228|UniProtKB=A6NI86 A6NI86 GOLGA6L10 PTHR23143:SF19 TRICHOHYALIN-RELATED GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 10-RELATED actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=13051|UniProtKB=O75312 O75312 ZPR1 PTHR10876:SF3 ZINC FINGER PROTEIN ZPR1 ZINC FINGER PROTEIN ZPR1 protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 positive regulation of gene expression#GO:0010628;cellular localization#GO:0051641;cell projection organization#GO:0030030;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;protein import#GO:0017038;positive regulation of biological process#GO:0048518;nuclear transport#GO:0051169;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;positive regulation of transport#GO:0051050;cellular component organization#GO:0016043;regulation of cellular localization#GO:0060341;peptide transport#GO:0015833;positive regulation of macromolecule metabolic process#GO:0010604;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;protein transport#GO:0015031;neuron development#GO:0048666;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of metabolic process#GO:0019222;regulation of peptide transport#GO:0090087;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;developmental process#GO:0032502;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;amide transport#GO:0042886;protein import into nucleus#GO:0006606;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;positive regulation of metabolic process#GO:0009893;regulation of transport#GO:0051049;neuron differentiation#GO:0030182;protein localization to organelle#GO:0033365;regulation of gene expression#GO:0010468;regulation of protein transport#GO:0051223;metabolic process#GO:0008152;multicellular organism development#GO:0007275;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;localization#GO:0051179;cell development#GO:0048468;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;nucleocytoplasmic transport#GO:0006913;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;generation of neurons#GO:0048699;import into nucleus#GO:0051170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;nuclear body#GO:0016604;membrane#GO:0016020;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;intracellular#GO:0005622;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;nuclear lumen#GO:0031981;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=9832|UniProtKB=P55895 P55895 RAG2 PTHR10960:SF0 V D J RECOMBINATION-ACTIVATING PROTEIN 2 V(D)J RECOMBINATION-ACTIVATING PROTEIN 2 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;V(D)J recombination#GO:0033151;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;immune system process#GO:0002376;system development#GO:0048731;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;somatic cell DNA recombination#GO:0016444;nitrogen compound metabolic process#GO:0006807;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;somatic diversification of immune receptors#GO:0002200;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993 HUMAN|HGNC=6473|UniProtKB=P51826 P51826 AFF3 PTHR10528:SF16 AF4/FMR2 FAMILY MEMBER AF4/FMR2 FAMILY MEMBER 3 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023 DNA-binding transcription factor#PC00218 HUMAN|HGNC=9214|UniProtKB=Q03052 Q03052 POU3F1 PTHR11636:SF75 POU DOMAIN POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=27413|UniProtKB=A2AJT9 A2AJT9 BCLAF3 PTHR15268:SF17 THRAP3/BCLAF1 BCLAF1 AND THRAP3 FAMILY MEMBER 3 nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=25090|UniProtKB=Q96DG6 Q96DG6 CMBL PTHR46812:SF1 FAMILY NOT NAMED CARBOXYMETHYLENEBUTENOLIDASE HOMOLOG HUMAN|HGNC=13671|UniProtKB=Q96KK5 Q96KK5 H2AC12 PTHR23430:SF29 HISTONE H2A HISTONE H2A TYPE 1-H heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=23380|UniProtKB=Q9NY56 Q9NY56 OBP2A PTHR11430:SF129 LIPOCALIN ODORANT-BINDING PROTEIN 2A-RELATED binding#GO:0005488 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 HUMAN|HGNC=20044|UniProtKB=Q8WXD5 Q8WXD5 GEMIN6 PTHR14710:SF2 GEM-ASSOCIATED PROTEIN 6 GEM-ASSOCIATED PROTEIN 6 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;intracellular#GO:0005622 HUMAN|HGNC=5196|UniProtKB=Q9Y663 Q9Y663 HS3ST3A1 PTHR10605:SF64 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 3A1 transferase#PC00220 HUMAN|HGNC=22923|UniProtKB=Q96IJ6 Q96IJ6 GMPPA PTHR22572:SF104 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE ALPHA transferase#PC00220 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 HUMAN|HGNC=9195|UniProtKB=P52434 P52434 POLR2H PTHR10917:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;RNA polymerase II, holoenzyme#GO:0016591;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 HUMAN|HGNC=23025|UniProtKB=Q8TD94 Q8TD94 KLF14 PTHR23235:SF59 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 14 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=30693|UniProtKB=Q5VWM3 Q5VWM3 PRAMEF18 PTHR14224:SF79 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 18-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=13543|UniProtKB=O94823 O94823 ATP10B PTHR24092:SF79 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE VB-RELATED pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=14251|UniProtKB=Q8WY22 Q8WY22 BRI3BP PTHR31253:SF0 BRI3-BINDING PROTEIN BRI3-BINDING PROTEIN HUMAN|HGNC=20066|UniProtKB=Q70CQ2 Q70CQ2 USP34 PTHR24006:SF671 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=16369|UniProtKB=Q99497 Q99497 PARK7 PTHR48094:SF16 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED PARKINSON DISEASE PROTEIN 7 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity, acting on a protein#GO:0140096;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;alcohol biosynthetic process#GO:0046165;protein modification process#GO:0036211;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;monocarboxylic acid biosynthetic process#GO:0072330;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=21629|UniProtKB=Q8TAF7 Q8TAF7 ZNF461 PTHR24377:SF277 IP01015P-RELATED ZINC FINGER PROTEIN 461 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=3596|UniProtKB=Q9NYQ8 Q9NYQ8 FAT2 PTHR24026:SF37 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN FAT 2 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=24904|UniProtKB=Q70IA6 Q70IA6 MOB2 PTHR22599:SF21 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 2 kinase activator#PC00138 HUMAN|HGNC=18801|UniProtKB=Q7Z3K3 Q7Z3K3 POGZ PTHR24403:SF59 ZINC FINGER PROTEIN POGO TRANSPOSABLE ELEMENT WITH ZNF DOMAIN positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=8573|UniProtKB=P09466 P09466 PAEP PTHR11430:SF117 LIPOCALIN GLYCODELIN binding#GO:0005488 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 HUMAN|HGNC=16009|UniProtKB=Q9Y574 Q9Y574 ASB4 PTHR24123:SF33 ANKYRIN REPEAT-CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 4 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29934|UniProtKB=Q6ZQQ6 Q6ZQQ6 WDR87 PTHR42968:SF9 WD REPEAT-CONTAINING WD REPEAT-CONTAINING PROTEIN 87 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6246|UniProtKB=Q9H3M0 Q9H3M0 KCNF1 PTHR11537:SF171 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY F MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=13144|UniProtKB=Q16587 Q16587 ZNF74 PTHR24377:SF336 IP01015P-RELATED ZINC FINGER PROTEIN 74 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24726|UniProtKB=Q8N3J2 Q8N3J2 METTL4 PTHR12829:SF4 N6-ADENOSINE-METHYLTRANSFERASE N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4 RNA methyltransferase#PC00033 HUMAN|HGNC=9349|UniProtKB=Q9NQX1 Q9NQX1 PRDM5 PTHR16515:SF32 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 5 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;repressing transcription factor binding#GO:0070491;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;histone methylation#GO:0016571;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein alkylation#GO:0008213;protein methylation#GO:0006479;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;histone lysine methylation#GO:0034968;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=2294|UniProtKB=P10176 P10176 COX8A PTHR16717:SF1 CYTOCHROME C OXIDASE POLYPEPTIDE VIII CYTOCHROME C OXIDASE SUBUNIT 8A, MITOCHONDRIAL cytoplasm#GO:0005737;respirasome#GO:0070469;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cytochrome complex#GO:0070069;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidase#PC00175 HUMAN|HGNC=28720|UniProtKB=Q9H6J7 Q9H6J7 C11orf49 PTHR34252:SF1 UPF0705 PROTEIN C11ORF49 UPF0705 PROTEIN C11ORF49 HUMAN|HGNC=18906|UniProtKB=P0C7H8 P0C7H8 KRTAP2-3 PTHR23262:SF199 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 2-2-RELATED HUMAN|HGNC=26771|UniProtKB=Q8N944 Q8N944 AMER3 PTHR22237:SF2 UNCHARACTERIZED APC MEMBRANE RECRUITMENT PROTEIN 3 phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;beta-catenin binding#GO:0008013 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=17073|UniProtKB=Q9UNA1 Q9UNA1 ARHGAP26 PTHR12552:SF4 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 26 GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257 Integrin signalling pathway#P00034>GRAF#P00926;PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=21016|UniProtKB=Q5TDP6 Q5TDP6 LGSN PTHR43407:SF1 GLUTAMINE SYNTHETASE LENGSIN ligase activity#GO:0016874;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;transport#GO:0006810;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;nitrogen compound transport#GO:0071705;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;localization#GO:0051179;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968 HUMAN|HGNC=25777|UniProtKB=Q2KHR2 Q2KHR2 RFX7 PTHR12619:SF2 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=16814|UniProtKB=Q96NX9 Q96NX9 DACH2 PTHR12577:SF7 DACHSHUND DACHSHUND HOMOLOG 2 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=21722|UniProtKB=Q8N865 Q8N865 C7orf31 PTHR31393:SF2 C5ORF31 CHROMOSOME 7 OPEN READING FRAME 31 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=18585|UniProtKB=Q96DH6 Q96DH6 MSI2 PTHR48032:SF10 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 RNA-BINDING PROTEIN MUSASHI HOMOLOG 2 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;polysome#GO:0005844;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=28443|UniProtKB=Q8WUR7 Q8WUR7 C15orf40 PTHR13420:SF7 UNCHARACTERIZED UPF0235 PROTEIN C15ORF40 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=16776|UniProtKB=Q9BQ66 Q9BQ66 KRTAP4-12 PTHR23262:SF219 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-12 HUMAN|HGNC=17182|UniProtKB=Q9H672 Q9H672 ASB7 PTHR24118:SF40 POTE ANKYRIN DOMAIN ANKYRIN REPEAT AND SOCS BOX PROTEIN 7 membrane traffic protein#PC00150 HUMAN|HGNC=17261|UniProtKB=Q9Y3A3 Q9Y3A3 MOB4 PTHR22599:SF56 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB-LIKE PROTEIN PHOCEIN kinase activator#PC00138 HUMAN|HGNC=33178|UniProtKB=Q5MJ07 Q5MJ07 SPANXN5 PTHR23425:SF17 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME N5 HUMAN|HGNC=2897|UniProtKB=Q96QB1 Q96QB1 DLC1 PTHR12659:SF2 RHO-TYPE GTPASE ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 7 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;Rho protein signal transduction#GO:0007266;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;actin cytoskeleton organization#GO:0030036;signaling#GO:0023052;regulation of Ras protein signal transduction#GO:0046578 anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;membrane raft#GO:0045121;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane microdomain#GO:0098857;membrane region#GO:0098589;whole membrane#GO:0098805 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=10791|UniProtKB=Q13242 Q13242 SRSF9 PTHR23147:SF59 SERINE/ARGININE RICH SPLICING FACTOR SERINE/ARGININE-RICH SPLICING FACTOR 9 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=27050|UniProtKB=Q7Z5W3 Q7Z5W3 BCDIN3D PTHR12315:SF1 BICOID-INTERACTING PROTEIN RELATED RNA 5'-MONOPHOSPHATE METHYLTRANSFERASE catalytic activity, acting on RNA#GO:0140098;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;gene silencing by miRNA#GO:0035195;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;gene silencing by RNA#GO:0031047;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;production of miRNAs involved in gene silencing by miRNA#GO:0035196;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;posttranscriptional gene silencing#GO:0016441;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=18608|UniProtKB=Q38SD2 Q38SD2 LRRK1 PTHR45752:SF71 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT SERINE/THREONINE-PROTEIN KINASE 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=24105|UniProtKB=Q96FJ0 Q96FJ0 STAMBPL1 PTHR12947:SF7 AMSH-LIKE PROTEASE AMSH-LIKE PROTEASE thiol-dependent ubiquitin-specific protease activity#GO:0004843;hydrolase activity#GO:0016787;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein K63-linked deubiquitination#GO:0070536;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=43626|UniProtKB=A0A1W2PQ27 A0A1W2PQ27 SSU72P7 PTHR20383:SF10 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;mRNA 3'-end processing#GO:0031124;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;mRNA polyadenylation#GO:0006378;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;dephosphorylation#GO:0016311;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 protein phosphatase#PC00195 HUMAN|HGNC=14652|UniProtKB=Q9NVD7 Q9NVD7 PARVA PTHR12114:SF6 PARVIN ALPHA-PARVIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;actin cytoskeleton reorganization#GO:0031532;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell adhesion#GO:0007155;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cell-substrate adhesion#GO:0031589;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;anatomical structure development#GO:0048856;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;establishment or maintenance of cell polarity#GO:0007163;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;biological adhesion#GO:0022610;developmental process#GO:0032502;transport#GO:0006810;substrate adhesion-dependent cell spreading#GO:0034446;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;cell differentiation#GO:0030154;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;cell morphogenesis involved in differentiation#GO:0000904;vesicle localization#GO:0051648;cell morphogenesis#GO:0000902;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cell development#GO:0048468;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;intracellular#GO:0005622;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Parvin#P00945 HUMAN|HGNC=2622|UniProtKB=P10632 P10632 CYP2C8 PTHR24300:SF317 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C8 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=31369|UniProtKB=Q8N4H5 Q8N4H5 TOMM5 PTHR28436:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM5 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM5 HOMOLOG envelope#GO:0031975;mitochondrial protein complex#GO:0098798;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 primary active transporter#PC00068 HUMAN|HGNC=6508|UniProtKB=O43813 O43813 LANCL1 PTHR12736:SF5 LANC-LIKE PROTEIN GLUTATHIONE S-TRANSFERASE LANCL1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=25334|UniProtKB=Q8N336 Q8N336 ELMOD1 PTHR12771:SF18 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 1 GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18483|UniProtKB=Q8WWY8 Q8WWY8 LIPH PTHR11610:SF12 LIPASE LIPASE MEMBER H hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular lipid catabolic process#GO:0044242;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;triglyceride metabolic process#GO:0006641;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerolipid catabolic process#GO:0046503;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143 2-arachidonoylglycerol biosynthesis#P05726>PLA1#P05735 HUMAN|HGNC=23696|UniProtKB=Q7Z3E1 Q7Z3E1 TIPARP PTHR45740:SF7 POLY [ADP-RIBOSE] POLYMERASE PROTEIN MONO-ADP-RIBOSYLTRANSFERASE TIPARP HUMAN|HGNC=18738|UniProtKB=O94844 O94844 RHOBTB1 PTHR24072:SF120 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;membrane organization#GO:0061024;transport#GO:0006810;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;vesicle organization#GO:0016050;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;phagocytosis#GO:0006909;regulation of organelle organization#GO:0033043;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036;apoptotic cell clearance#GO:0043277 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=3259|UniProtKB=Q9NR50 Q9NR50 EIF2B3 PTHR45989:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;guanyl-nucleotide exchange factor activity#GO:0005085 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=20789|UniProtKB=Q86TL0 Q86TL0 ATG4D PTHR22624:SF36 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4D cysteine protease#PC00081 HUMAN|HGNC=9390|UniProtKB=P31321 P31321 PRKAR1B PTHR11635:SF126 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I-BETA REGULATORY SUBUNIT kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>PKA#P06782;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;GABA-B receptor II signaling#P05731>PKA#P05752;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Hedgehog signaling pathway#P00025>PKA#P00682;Endothelin signaling pathway#P00019>PKA#P00570;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 HUMAN|HGNC=20760|UniProtKB=Q9BQ24 Q9BQ24 ZFYVE21 PTHR39490:SF8 ARRESTIN DOMAIN-CONTAINING PROTEIN D ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21 HUMAN|HGNC=16705|UniProtKB=Q5XG87 Q5XG87 TENT4A PTHR23092:SF24 POLY(A) RNA POLYMERASE TERMINAL NUCLEOTIDYLTRANSFERASE 4A adenylyltransferase activity#GO:0070566;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=34344|UniProtKB=A6NDX5 A6NDX5 ZNF840P PTHR24376:SF189 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 840-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 HUMAN|HGNC=42959|UniProtKB=Q92843 Q92843 BCL2L2 PTHR11256:SF13 BCL-2 RELATED BCL-2-LIKE PROTEIN 2 identical protein binding#GO:0042802;protein binding#GO:0005515;protein homodimerization activity#GO:0042803;binding#GO:0005488 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;cell death#GO:0008219;intracellular signal transduction#GO:0035556;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;negative regulation of cell death#GO:0060548;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of intrinsic apoptotic signaling pathway#GO:2001242;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>Bcl-w#P00316 HUMAN|HGNC=16111|UniProtKB=O94964 O94964 SOGA1 PTHR15742:SF1 UNCHARACTERIZED PROTEIN SOGA1 HUMAN|HGNC=1777|UniProtKB=Q00534 Q00534 CDK6 PTHR24056:SF130 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 6 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=28618|UniProtKB=Q8N2U0 Q8N2U0 TMEM256 PTHR43461:SF1 TRANSMEMBRANE PROTEIN 256 TRANSMEMBRANE PROTEIN 256 HUMAN|HGNC=12478|UniProtKB=Q96LR5 Q96LR5 UBE2E2 PTHR24068:SF429 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 E2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=16712|UniProtKB=Q969H0 Q969H0 FBXW7 PTHR19849:SF1 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN F-BOX/WD REPEAT-CONTAINING PROTEIN 7 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Notch signaling pathway#P00045>Sel 10#P01102;Parkinson disease#P00049>hSel10#P01240 HUMAN|HGNC=25972|UniProtKB=Q2M2I3 Q2M2I3 FAM83E PTHR16181:SF12 UNCHARACTERIZED PROTEIN FAM83E HUMAN|HGNC=6742|UniProtKB=Q8N653 Q8N653 LZTR1 PTHR46376:SF1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=7525|UniProtKB=O15146 O15146 MUSK PTHR24416:SF317 TYROSINE-PROTEIN KINASE RECEPTOR MUSCLE, SKELETAL RECEPTOR TYROSINE-PROTEIN KINASE signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=11919|UniProtKB=P25942 P25942 CD40 PTHR46875:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5 binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;positive regulation of signal transduction#GO:0009967;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;lymphocyte mediated immunity#GO:0002449;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;peptidyl-tyrosine phosphorylation#GO:0018108;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;tube morphogenesis#GO:0035239;positive regulation of receptor signaling pathway via STAT#GO:1904894;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;somatic diversification of immune receptors#GO:0002200;leukocyte activation#GO:0045321;lymphocyte activation involved in immune response#GO:0002285;regulation of protein secretion#GO:0050708;localization of cell#GO:0051674;cell communication#GO:0007154;endothelial cell migration#GO:0043542;positive regulation of lymphocyte mediated immunity#GO:0002708;DNA recombination#GO:0006310;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;cell activation#GO:0001775;establishment of protein localization to extracellular region#GO:0035592;nucleobase-containing compound biosynthetic process#GO:0034654;angiogenesis#GO:0001525;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;protein localization to extracellular region#GO:0071692;regulation of phosphorylation#GO:0042325;regulation of locomotion#GO:0040012;RNA metabolic process#GO:0016070;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;organic substance transport#GO:0071702;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;regulation of peptide secretion#GO:0002791;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;positive regulation of programmed cell death#GO:0043068;somatic cell DNA recombination#GO:0016444;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of cell motility#GO:2000147;cellular nitrogen compound biosynthetic process#GO:0044271;cell death#GO:0008219;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;immune effector process#GO:0002252;signaling#GO:0023052;secretion by cell#GO:0032940;nucleic acid-templated transcription#GO:0097659;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;lymphocyte proliferation#GO:0046651;cell motility#GO:0048870;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of DNA-binding transcription factor activity#GO:0051091;positive regulation of protein metabolic process#GO:0051247;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;response to other organism#GO:0051707;regulation of lymphocyte proliferation#GO:0050670;regulation of cell death#GO:0010941;positive regulation of cell death#GO:0010942;transcription by RNA polymerase II#GO:0006366;regulation of B cell proliferation#GO:0030888;response to external biotic stimulus#GO:0043207;regulation of protein modification process#GO:0031399;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component movement#GO:0051272;positive regulation of leukocyte activation#GO:0002696;regulation of cell activation#GO:0050865;regulation of phosphorus metabolic process#GO:0051174;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of secretion#GO:0051046;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;vasculature development#GO:0001944;intracellular signal transduction#GO:0035556;mononuclear cell proliferation#GO:0032943;organic substance metabolic process#GO:0071704;circulatory system development#GO:0072359;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of locomotion#GO:0040017;tube development#GO:0035295;peptide transport#GO:0015833;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of production of molecular mediator of immune response#GO:0002700;aromatic compound biosynthetic process#GO:0019438;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of cellular metabolic process#GO:0031323;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;positive regulation of nitrogen compound metabolic process#GO:0051173;response to virus#GO:0009615;regulation of phosphate metabolic process#GO:0019220;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;transport#GO:0006810;regulation of angiogenesis#GO:0045765;peptide secretion#GO:0002790;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of gene expression#GO:0010468;regulation of lymphocyte activation#GO:0051249;receptor signaling pathway via JAK-STAT#GO:0007259;regulation of cytokine production#GO:0001817;regulation of apoptotic process#GO:0042981;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of RNA metabolic process#GO:0051252;positive regulation of developmental process#GO:0051094;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of leukocyte activation#GO:0002694;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of leukocyte proliferation#GO:0070663;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477;DNA metabolic process#GO:0006259;immune response-regulating signaling pathway#GO:0002764;response to cytokine#GO:0034097;gene expression#GO:0010467;regulation of localization#GO:0032879;B cell proliferation#GO:0042100;positive regulation of lymphocyte activation#GO:0051251;production of molecular mediator of immune response#GO:0002440;secretion#GO:0046903;innate immune response#GO:0045087;regulation of adaptive immune response#GO:0002819;defense response#GO:0006952;regulation of protein localization#GO:0032880;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;tyrosine phosphorylation of STAT protein#GO:0007260;primary metabolic process#GO:0044238;positive regulation of cell communication#GO:0010647;export from cell#GO:0140352;regulation of peptide transport#GO:0090087;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of angiogenesis#GO:0045766;positive regulation of RNA biosynthetic process#GO:1902680;regulation of anatomical structure morphogenesis#GO:0022603;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;protein modification process#GO:0036211;positive regulation of adaptive immune response#GO:0002821;cytokine production#GO:0001816;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;amide transport#GO:0042886;somatic recombination of immunoglobulin gene segments#GO:0016447;regulation of biosynthetic process#GO:0009889;positive regulation of immunoglobulin mediated immune response#GO:0002891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of protein transport#GO:0051223;regulation of programmed cell death#GO:0043067;heterocycle metabolic process#GO:0046483;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;immunoglobulin production#GO:0002377;regulation of cell population proliferation#GO:0042127;protein phosphorylation#GO:0006468;cellular process#GO:0009987;immune system process#GO:0002376;regulation of immune effector process#GO:0002697;positive regulation of cell migration#GO:0030335;regulation of mononuclear cell proliferation#GO:0032944;receptor signaling pathway via STAT#GO:0097696;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;positive regulation of immunoglobulin production#GO:0002639;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA recombination#GO:0000018;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of transcription by RNA polymerase II#GO:0045944;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;protein secretion#GO:0009306;cell population proliferation#GO:0008283;establishment of protein localization#GO:0045184;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;positive regulation of immune effector process#GO:0002699;positive regulation of cytokine production#GO:0001819;defense response to virus#GO:0051607;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;B cell activation involved in immune response#GO:0002312;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of transcription, DNA-templated#GO:0045893;blood vessel morphogenesis#GO:0048514;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;RNA biosynthetic process#GO:0032774;toll-like receptor signaling pathway#GO:0002224;protein localization#GO:0008104;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;response to stress#GO:0006950;leukocyte activation involved in immune response#GO:0002366;protein transport#GO:0015031;blood vessel development#GO:0001568;response to interleukin-1#GO:0070555;movement of cell or subcellular component#GO:0006928;positive regulation of cell activation#GO:0050867;regulation of establishment of protein localization#GO:0070201;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of transcription, DNA-templated#GO:0006355;regulation of transport#GO:0051049;regulation of lymphocyte mediated immunity#GO:0002706;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;response to organic substance#GO:0010033;cellular macromolecule biosynthetic process#GO:0034645;lymphocyte activation#GO:0046649;regulation of cell motility#GO:2000145;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;leukocyte mediated immunity#GO:0002443;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;response to external stimulus#GO:0009605;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;peptidyl-tyrosine modification#GO:0018212;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;cellular response to cytokine stimulus#GO:0071345;biological regulation#GO:0065007;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane protein complex#GO:0098796;leaflet of membrane bilayer#GO:0097478;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;receptor complex#GO:0043235;cell surface#GO:0009986;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=10545|UniProtKB=Q15800 Q15800 MSMO1 PTHR11863:SF3 STEROL DESATURASE METHYLSTEROL MONOOXYGENASE 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxidase#PC00175 HUMAN|HGNC=9244|UniProtKB=O14830 O14830 PPEF2 PTHR45668:SF2 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;heat shock protein binding#GO:0031072;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;Hsp90 protein binding#GO:0051879;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 HUMAN|HGNC=23615|UniProtKB=Q8IXU6 Q8IXU6 SLC35F2 PTHR14233:SF12 DUF914-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F2 HUMAN|HGNC=1850|UniProtKB=Q9NYQ6 Q9NYQ6 CELSR1 PTHR24026:SF36 FAT ATYPICAL CADHERIN-RELATED CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 1 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=23295|UniProtKB=Q9BQ13 Q9BQ13 KCTD14 PTHR14499:SF3 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD14 scaffold/adaptor protein#PC00226 HUMAN|HGNC=23097|UniProtKB=Q7RTT9 Q7RTT9 SLC29A4 PTHR10332:SF4 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=17585|UniProtKB=Q6ZWJ8 Q6ZWJ8 KCP PTHR46698:SF2 CROSSVEINLESS 2 KIELIN/CHORDIN-LIKE PROTEIN HUMAN|HGNC=28755|UniProtKB=Q8IVY1 Q8IVY1 C1orf210 PTHR31450:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19 LRRC19 FAMILY MEMBER TYPE III ENDOSOME MEMBRANE PROTEIN TEMP HUMAN|HGNC=11499|UniProtKB=O43760 O43760 SYNGR2 PTHR10838:SF30 SYNAPTOGYRIN SYNAPTOGYRIN-2 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=9525|UniProtKB=Q9UQ74 Q9UQ74 PSG8 PTHR44427:SF3 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 8 HUMAN|Ensembl=ENSG00000278776|UniProtKB=A0A0G2JMP0 A0A0G2JMP0 ENSG00000278776 PTHR48002:SF103 OLFACTORY RECEPTOR G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=16378|UniProtKB=Q7RTW8 Q7RTW8 OTOA PTHR23412:SF18 STEREOCILIN RELATED OTOANCORIN cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;biological adhesion#GO:0022610 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 HUMAN|HGNC=9645|UniProtKB=Q05209 Q05209 PTPN12 PTHR45983:SF3 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 12 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Integrin signalling pathway#P00034>PTP-PEST#P00915 HUMAN|HGNC=428|UniProtKB=Q8TCU4 Q8TCU4 ALMS1 PTHR21553:SF22 ALMS1-RELATED ALSTROM SYNDROME PROTEIN 1 regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;regulation of centrosome duplication#GO:0010824 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=27193|UniProtKB=Q17R98 Q17R98 ZNF827 PTHR24403:SF62 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 827 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25407|UniProtKB=Q96QD9 Q96QD9 FYTTD1 PTHR21038:SF2 40-2-3 PROTEIN-RELATED UAP56-INTERACTING FACTOR HUMAN|HGNC=26862|UniProtKB=Q4G112 Q4G112 HSF5 PTHR10015:SF278 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 5 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=23419|UniProtKB=Q96EK5 Q96EK5 KIFBP PTHR46321:SF1 KIF1-BINDING PROTEIN KIF-BINDING PROTEIN HUMAN|HGNC=21688|UniProtKB=O43257 O43257 ZNHIT1 PTHR13093:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1 ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 1 nucleosome binding#GO:0031491;enzyme binding#GO:0019899;protein binding#GO:0005515;histone deacetylase binding#GO:0042826;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 regulation of protein modification process#GO:0031399;histone exchange#GO:0043486;nucleosome organization#GO:0034728;protein deacetylation#GO:0006476;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;regulation of histone modification#GO:0031056;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;regulation of chromatin organization#GO:1902275;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;protein-DNA complex subunit organization#GO:0071824;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;histone modification#GO:0016570;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule deacylation#GO:0098732;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;protein deacylation#GO:0035601;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=12006|UniProtKB=Q16890 Q16890 TPD52L1 PTHR19307:SF8 TUMOR PROTEIN D52 TUMOR PROTEIN D53 HUMAN|HGNC=30714|UniProtKB=Q8NCV1 Q8NCV1 ADAD2 PTHR10910:SF106 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;double-stranded RNA binding#GO:0003725 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=21747|UniProtKB=Q17RY0 Q17RY0 CPEB4 PTHR12566:SF2 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 synapse#GO:0045202;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=29084|UniProtKB=O75123 O75123 ZNF623 PTHR24377:SF244 IP01015P-RELATED ZINC FINGER PROTEIN 623 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=5422|UniProtKB=P01571 P01571 IFNA17 PTHR11691:SF66 TYPE I INTERFERON INTERFERON ALPHA-10-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=6140|UniProtKB=P13612 P13612 ITGA4 PTHR23220:SF78 INTEGRIN ALPHA INTEGRIN ALPHA-4 integrin#PC00126 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=26442|UniProtKB=Q96DE0 Q96DE0 NUDT16 PTHR31699:SF5 NUDIX T16 FAMILY MEMBER U8 SNORNA-DECAPPING ENZYME snoRNA binding#GO:0030515;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11133|UniProtKB=O95721 O95721 SNAP29 PTHR19305:SF9 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 29 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 SNARE protein#PC00034 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 HUMAN|HGNC=37326|UniProtKB=A8MTI9 A8MTI9 PRSS47 PTHR24256:SF214 TRYPTASE-RELATED SERINE PROTEASE 47-RELATED serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=15111|UniProtKB=Q8NGR9 Q8NGR9 OR1N2 PTHR48001:SF135 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1N2 transmembrane signal receptor#PC00197 HUMAN|HGNC=13166|UniProtKB=Q05481 Q05481 ZNF91 PTHR24376:SF210 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 721-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=24989|UniProtKB=Q9NZL4 Q9NZL4 HSPBP1 PTHR19316:SF18 PROTEIN FOLDING REGULATOR HSP70-BINDING PROTEIN 1 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=18162|UniProtKB=Q86UV7 Q86UV7 TRIM73 PTHR24103:SF662 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 73-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=11873|UniProtKB=Q9NYL9 Q9NYL9 TMOD3 PTHR10901:SF18 TROPOMODULIN TROPOMODULIN-3 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=16807|UniProtKB=Q9HCE7 Q9HCE7 SMURF1 PTHR11254:SF293 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF1 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;protein catabolic process#GO:0030163;regulation of BMP signaling pathway#GO:0030510;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to endogenous stimulus#GO:0071495;protein modification by small protein conjugation or removal#GO:0070647;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;positive regulation of catabolic process#GO:0009896;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;negative regulation of signal transduction#GO:0009968;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;negative regulation of BMP signaling pathway#GO:0030514;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cellular protein catabolic process#GO:0044257;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490;TGF-beta signaling pathway#P00052>Smurfs#P01279 HUMAN|HGNC=44296|UniProtKB=Q86TS7 Q86TS7 LINC00643 PTHR47888:SF1 UPF0730 PROTEIN ENCODED BY LINC00643-RELATED UPF0730 PROTEIN ENCODED BY LINC00643-RELATED HUMAN|HGNC=32057|UniProtKB=Q5T870 Q5T870 PRR9 PTHR23263:SF26 SMALL PROLINE-RICH PROTEIN PROLINE-RICH PROTEIN 9 HUMAN|HGNC=6387|UniProtKB=Q07866 Q07866 KLC1 PTHR45783:SF7 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 1 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 HUMAN|HGNC=8056|UniProtKB=Q9BW91 Q9BW91 NUDT9 PTHR13030:SF8 NUDIX HYDROLASE ADP-RIBOSE PYROPHOSPHATASE, MITOCHONDRIAL hydrolase#PC00121 HUMAN|HGNC=6362|UniProtKB=Q9P0G3 Q9P0G3 KLK14 PTHR24271:SF48 KALLIKREIN-RELATED KALLIKREIN-14 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=18652|UniProtKB=Q9P1Q0 Q9P1Q0 VPS54 PTHR12965:SF0 VACUOLAR PROTEIN SORTING 54 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54 syntaxin binding#GO:0019905;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=20043|UniProtKB=Q8TEQ6 Q8TEQ6 GEMIN5 PTHR46362:SF1 GEM-ASSOCIATED PROTEIN 5 GEM-ASSOCIATED PROTEIN 5 HUMAN|HGNC=1097|UniProtKB=P15056 P15056 BRAF PTHR44329:SF240 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED SERINE/THREONINE-PROTEIN KINASE B-RAF transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cell periphery#GO:0071944;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>Raf#P01417;Integrin signalling pathway#P00034>Raf#P00924;EGF receptor signaling pathway#P00018>Raf-1#P00560;PDGF signaling pathway#P00047>Raf#P01161;Angiogenesis#P00005>Raf#P00243;Interleukin signaling pathway#P00036>Raf#P00983;Integrin signalling pathway#P00034>B-Raf#P00911;Ras Pathway#P04393>Raf#P04556;B cell activation#P00010>Raf#P00381;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Raf-1#P00843;CCKR signaling map#P06959>B-Raf#P07057;T cell activation#P00053>Raf#P01311 HUMAN|HGNC=7975|UniProtKB=P10589 P10589 NR2F1 PTHR24083:SF168 NUCLEAR HORMONE RECEPTOR COUP TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=28490|UniProtKB=Q8NDZ4 Q8NDZ4 DIPK2A PTHR32073:SF6 GH11358P DIVERGENT PROTEIN KINASE DOMAIN 2A HUMAN|HGNC=8162|UniProtKB=P58181 P58181 OR10A3 PTHR26453:SF30 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A3 transmembrane signal receptor#PC00197 HUMAN|HGNC=15487|UniProtKB=Q9H3N1 Q9H3N1 TMX1 PTHR46107:SF2 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 1 HUMAN|HGNC=7010|UniProtKB=O00255 O00255 MEN1 PTHR12693:SF3 MENIN MENIN N-methyltransferase activity#GO:0008170;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;double-stranded DNA binding#GO:0003690;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;sequence-specific double-stranded DNA binding#GO:1990837;histone-lysine N-methyltransferase activity#GO:0018024;sequence-specific DNA binding#GO:0043565;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of cell population proliferation#GO:0008285;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 CCKR signaling map#P06959>MEN1#P07084 HUMAN|HGNC=14982|UniProtKB=Q9BWT3 Q9BWT3 PAPOLG PTHR10682:SF6 POLY A POLYMERASE POLY(A) POLYMERASE GAMMA adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=29860|UniProtKB=Q6DHY5 Q6DHY5 TBC1D3G PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=26117|UniProtKB=Q5T447 Q5T447 HECTD3 PTHR46654:SF1 E3 UBIQUITIN-PROTEIN LIGASE HECTD3 E3 UBIQUITIN-PROTEIN LIGASE HECTD3 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=32205|UniProtKB=A6NDN3 A6NDN3 GOLGA6B PTHR10881:SF44 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 6A-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=21378|UniProtKB=Q5TC84 Q5TC84 OGFRL1 PTHR14015:SF0 OPIOID GROWTH FACTOR RECEPTOR OGFR ZETA-TYPE OPIOID RECEPTOR OPIOID GROWTH FACTOR RECEPTOR-LIKE PROTEIN 1 transmembrane signal receptor#PC00197 HUMAN|HGNC=10760|UniProtKB=Q01105 Q01105 SET PTHR11875:SF67 TESTIS-SPECIFIC Y-ENCODED PROTEIN PROTEIN SET protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=2135|UniProtKB=Q86WG5 Q86WG5 SBF2 PTHR10807:SF4 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 13 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;phosphoric ester hydrolase activity#GO:0042578;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137;Ras GTPase binding#GO:0017016;hydrolase activity#GO:0016787;Ras guanyl-nucleotide exchange factor activity#GO:0005088;molecular function regulator#GO:0098772;protein binding#GO:0005515;Rab guanyl-nucleotide exchange factor activity#GO:0017112 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=537|UniProtKB=P07355 P07355 ANXA2 PTHR10502:SF18 ANNEXIN ANNEXIN A2-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calcium-binding protein#PC00060 HUMAN|HGNC=17265|UniProtKB=Q7Z7G0 Q7Z7G0 ABI3BP PTHR23197:SF10 TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING TARGET OF NESH-SH3 HUMAN|HGNC=29925|UniProtKB=Q13823 Q13823 GNL2 PTHR11089:SF9 GTP-BINDING PROTEIN-RELATED NUCLEOLAR GTP-BINDING PROTEIN 2 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16459|UniProtKB=Q9NYK6 Q9NYK6 EURL PTHR15961:SF3 PROTEIN EURL HOMOLOG PROTEIN EURL HOMOLOG HUMAN|HGNC=33251|UniProtKB=A6NN92 A6NN92 GJE1 PTHR11984:SF1 CONNEXIN GAP JUNCTION EPSILON-1 PROTEIN-RELATED gap junction#PC00105 HUMAN|HGNC=5440|UniProtKB=P38484 P38484 IFNGR2 PTHR20859:SF46 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON GAMMA RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interferon-gamma signaling pathway#P00035>IFNGR2#P00957;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866;Interferon-gamma signaling pathway#P00035>IFNGR1#P00959 HUMAN|HGNC=1800|UniProtKB=Q92903 Q92903 CDS1 PTHR13773:SF16 PHOSPHATIDATE CYTIDYLYLTRANSFERASE PHOSPHATIDATE CYTIDYLYLTRANSFERASE 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=15239|UniProtKB=Q6IF63 Q6IF63 OR52W1 PTHR26450:SF58 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52W1 transmembrane signal receptor#PC00197 HUMAN|HGNC=9993|UniProtKB=O94810 O94810 RGS11 PTHR45746:SF3 LP21163P REGULATOR OF G-PROTEIN SIGNALING 11 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=4221|UniProtKB=Q6KF10 Q6KF10 GDF6 PTHR11848:SF43 TGF-BETA FAMILY GROWTH/DIFFERENTIATION FACTOR 6 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=29460|UniProtKB=Q5TA81 Q5TA81 LCE2C PTHR23263:SF132 SMALL PROLINE-RICH PROTEIN LATE CORNIFIED ENVELOPE PROTEIN 2A-RELATED HUMAN|HGNC=1986|UniProtKB=Q99966 Q99966 CITED1 PTHR17045:SF6 MELANOCYTE SPECIFIC GENE RELATED CITED CBP/P300-INTERACTING TRANSACTIVATOR 1 transcription cofactor#PC00217 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 HUMAN|HGNC=23621|UniProtKB=Q7L4E1 Q7L4E1 MIGA2 PTHR21508:SF4 MITOGUARDIN MITOGUARDIN 2 mitochondrial fusion#GO:0008053;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;organelle fusion#GO:0048284 HUMAN|HGNC=39006|UniProtKB=Q9UQG0 Q9UQG0 ERVK-11 PTHR41694:SF4 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 10 POL PROTEIN-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 viral or transposable element protein#PC00237 HUMAN|HGNC=30968|UniProtKB=A6NGK3 A6NGK3 GAGE10 PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=9289|UniProtKB=Q96PQ5 Q96PQ5 PPP1R2P1 PTHR12398:SF37 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE INHIBITOR 2-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096;protein phosphatase inhibitor activity#GO:0004864 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;regulation of phosphoprotein phosphatase activity#GO:0043666;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of phosphatase activity#GO:0010921;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 phosphatase inhibitor#PC00183 HUMAN|HGNC=15962|UniProtKB=Q9HC52 Q9HC52 CBX8 PTHR46389:SF1 POLYCOMB GROUP PROTEIN PC CHROMOBOX PROTEIN HOMOLOG 8 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=11490|UniProtKB=Q9BX26 Q9BX26 SYCP2 PTHR15607:SF12 SYNAPTONEMAL COMPLEX PROTEIN-RELATED SYNAPTONEMAL COMPLEX PROTEIN 2 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=13310|UniProtKB=Q9NZD1 Q9NZD1 GPRC5D PTHR14511:SF16 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER D protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;protein kinase activity#GO:0004672;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 receptor complex#GO:0043235;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=29353|UniProtKB=Q6PI77 Q6PI77 BHLHB9 PTHR46414:SF2 PROTEIN BHLHB9-RELATED PROTEIN BHLHB9 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=3769|UniProtKB=Q01740 Q01740 FMO1 PTHR23023:SF154 DIMETHYLANILINE MONOOXYGENASE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 oxygenase#PC00177 HUMAN|HGNC=7746|UniProtKB=P51956 P51956 NEK3 PTHR44984:SF1 SERINE/THREONINE-PROTEIN KINASE NEK3 SERINE/THREONINE-PROTEIN KINASE NEK3 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=9157|UniProtKB=P54317 P54317 PNLIPRP2 PTHR11610:SF165 LIPASE PANCREATIC LIPASE-RELATED PROTEIN 2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 lipase#PC00143 HUMAN|HGNC=5861|UniProtKB=A0M8Q6 A0M8Q6 IGLC7 PTHR23266:SF296 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA CONSTANT 7 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=1063|UniProtKB=P30043 P30043 BLVRB PTHR43355:SF2 FLAVIN REDUCTASE (NADPH) FLAVIN REDUCTASE (NADPH) reductase#PC00198 HUMAN|HGNC=24912|UniProtKB=Q4G0J3 Q4G0J3 LARP7 PTHR22792:SF115 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 7 RNA metabolism protein#PC00031 HUMAN|HGNC=14416|UniProtKB=Q9NXB9 Q9NXB9 ELOVL2 PTHR11157:SF16 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=22934|UniProtKB=Q8NAB2 Q8NAB2 KBTBD3 PTHR24412:SF418 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 3 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29011|UniProtKB=O15050 O15050 TRANK1 PTHR21529:SF4 MAMMARY TURMOR VIRUS RECEPTOR HOMOLOG 1, 2 MTVR1, 2 TPR AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 HUMAN|HGNC=26952|UniProtKB=P0DN77 P0DN77 OPN1MW2 PTHR24240:SF17 OPSIN MEDIUM-WAVE-SENSITIVE OPSIN 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to abiotic stimulus#GO:0071214;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=24849|UniProtKB=Q6W3E5 Q6W3E5 GDPD4 PTHR23344:SF13 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN 4 phosphodiesterase#PC00185 HUMAN|HGNC=15515|UniProtKB=Q5VV41 Q5VV41 ARHGEF16 PTHR12845:SF3 GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 16 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=6799|UniProtKB=P43365 P43365 MAGEA12 PTHR11736:SF142 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 12 scaffold/adaptor protein#PC00226 HUMAN|HGNC=24462|UniProtKB=Q8IZS7 Q8IZS7 CLECL1 PTHR46746:SF4 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY F MEMBER 2 C-TYPE LECTIN-LIKE DOMAIN FAMILY 1 transmembrane signal receptor#PC00197 HUMAN|HGNC=1123|UniProtKB=Q13886 Q13886 KLF9 PTHR23235:SF114 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 9 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9074|UniProtKB=Q15195 Q15195 PLGLA PTHR24261:SF13 PLASMINOGEN-RELATED PLASMINOGEN-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 Blood coagulation#P00011>Plasmin#P00415;Blood coagulation#P00011>Plasminogen#P00408;Plasminogen activating cascade#P00050>Plasminogen#P01255;Plasminogen activating cascade#P00050>Plasmin#P01246 HUMAN|HGNC=28789|UniProtKB=Q96BY9 Q96BY9 SARAF PTHR15929:SF0 UNCHARACTERIZED STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR HUMAN|HGNC=1106|UniProtKB=Q9NXR7 Q9NXR7 BABAM2 PTHR15189:SF7 BRISC AND BRCA1-A COMPLEX MEMBER 2 BRISC AND BRCA1-A COMPLEX MEMBER 2 HUMAN|HGNC=18367|UniProtKB=Q9ULC6 Q9ULC6 PADI1 PTHR10837:SF11 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE TYPE-1 HUMAN|HGNC=27283|UniProtKB=Q8NHP8 Q8NHP8 PLBD2 PTHR12370:SF3 PHOSPHOLIPASE B-RELATED PHOSPHOLIPASE B-LIKE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 phospholipase#PC00186 HUMAN|HGNC=16005|UniProtKB=Q9Y543 Q9Y543 HES2 PTHR10985:SF15 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 HUMAN|HGNC=6825|UniProtKB=P49641 P49641 MAN2A2 PTHR11607:SF57 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2X hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=2699|UniProtKB=O15523 O15523 DDX3Y PTHR47958:SF72 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX3Y catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;cellular process#GO:0009987;multi-organism reproductive process#GO:0044703;multi-organism process#GO:0051704;multicellular organismal reproductive process#GO:0048609 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=29244|UniProtKB=Q68DU8 Q68DU8 KCTD16 PTHR14499:SF28 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD16 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of G protein-coupled receptor signaling pathway#GO:0008277;cellular process#GO:0009987;signaling#GO:0023052 presynapse#GO:0098793;synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29411|UniProtKB=Q14C87 Q14C87 TMEM132D PTHR13388:SF2 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 132D HUMAN|HGNC=4803|UniProtKB=P55084 P55084 HADHB PTHR18919:SF147 ACETYL-COA C-ACYLTRANSFERASE TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=28874|UniProtKB=Q496F6 Q496F6 CD300E PTHR11860:SF89 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 2 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=29255|UniProtKB=Q70EK8 Q70EK8 USP53 PTHR22975:SF6 UBIQUITIN SPECIFIC PROTEINASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 53 response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to mechanical stimulus#GO:0009612;sensory perception of sound#GO:0007605;system process#GO:0003008;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;response to abiotic stimulus#GO:0009628 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cysteine protease#PC00081 HUMAN|HGNC=27453|UniProtKB=Q96HE8 Q96HE8 TMEM80 PTHR13531:SF8 GEO07735P1-RELATED-RELATED TRANSMEMBRANE PROTEIN 80 vesicle targeting, to, from or within Golgi#GO:0048199;non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 HUMAN|HGNC=25508|UniProtKB=Q9H6D3 Q9H6D3 XKR8 PTHR16024:SF8 XK-RELATED PROTEIN XK-RELATED PROTEIN 8 cellular component biogenesis#GO:0044085;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;developmental process#GO:0032502;endomembrane system organization#GO:0010256;plasma membrane bounded cell projection organization#GO:0120036;lipid transport#GO:0006869;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anion transport#GO:0006820;apoptotic process#GO:0006915;lipid translocation#GO:0034204;cell death#GO:0008219;vesicle organization#GO:0016050;lipid localization#GO:0010876;phospholipid translocation#GO:0045332;cellular component assembly#GO:0022607;organophosphate ester transport#GO:0015748;phagocytosis#GO:0006909;organic anion transport#GO:0015711;ion transport#GO:0006811;endocytosis#GO:0006897;plasma membrane phospholipid scrambling#GO:0017121;vesicle-mediated transport#GO:0016192;programmed cell death#GO:0012501;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;phospholipid transport#GO:0015914;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;anatomical structure development#GO:0048856;biological regulation#GO:0065007;plasma membrane bounded cell projection assembly#GO:0120031;apoptotic cell clearance#GO:0043277 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=21251|UniProtKB=A2RUU4 A2RUU4 CLPSL1 PTHR10041:SF7 COLIPASE COLIPASE-LIKE PROTEIN 1 response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;response to chemical#GO:0042221 protein-binding activity modulator#PC00095 HUMAN|HGNC=10943|UniProtKB=Q15758 Q15758 SLC1A5 PTHR11958:SF19 SODIUM/DICARBOXYLATE SYMPORTER-RELATED NEUTRAL AMINO ACID TRANSPORTER B(0) primary active transporter#PC00068 HUMAN|HGNC=28441|UniProtKB=Q8TAK5 Q8TAK5 GABPB2 PTHR24193:SF86 ANKYRIN REPEAT PROTEIN GA-BINDING PROTEIN SUBUNIT BETA-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11105|UniProtKB=Q8TAQ2 Q8TAQ2 SMARCC2 PTHR12802:SF105 SWI/SNF COMPLEX-RELATED SWI/SNF COMPLEX SUBUNIT SMARCC2 cis-regulatory region sequence-specific DNA binding#GO:0000987;nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;histone binding#GO:0042393;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=24696|UniProtKB=Q8TER0 Q8TER0 SNED1 PTHR24044:SF411 NOTCH LIGAND FAMILY MEMBER SUSHI, NIDOGEN AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 HUMAN|HGNC=30776|UniProtKB=Q8N3X6 Q8N3X6 LCORL PTHR21545:SF10 TRANSCRIPTION FACTOR MLR1/2 LIGAND-DEPENDENT NUCLEAR RECEPTOR COREPRESSOR-LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=16664|UniProtKB=A8MX76 A8MX76 CAPN14 PTHR10183:SF302 CALPAIN CALPAIN-14 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=23287|UniProtKB=O95571 O95571 ETHE1 PTHR43084:SF1 PERSULFIDE DIOXYGENASE ETHE1 PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxygenase#PC00177 HUMAN|HGNC=6266|UniProtKB=P48544 P48544 KCNJ5 PTHR11767:SF52 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083 HUMAN|HGNC=3758|UniProtKB=Q14254 Q14254 FLOT2 PTHR13806:SF31 FLOTILLIN-RELATED FLOTILLIN-2 protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=10488|UniProtKB=P31949 P31949 S100A11 PTHR11639:SF60 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A11 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=14169|UniProtKB=Q6P587 Q6P587 FAHD1 PTHR11820:SF106 ACYLPYRUVASE ACYLPYRUVASE FAHD1, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 hydrolase#PC00121 HUMAN|HGNC=13971|UniProtKB=Q9UGF5 Q9UGF5 OR14J1 PTHR26452:SF42 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14J1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=17343|UniProtKB=P31941 P31941 APOBEC3A PTHR13857:SF39 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3A-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363 response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;RNA phosphodiester bond hydrolysis#GO:0090501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;defense response to virus#GO:0051607;demethylation#GO:0070988;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;transposition#GO:0032196;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;RNA-dependent DNA biosynthetic process#GO:0006278;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;nucleic acid phosphodiester bond hydrolysis#GO:0090305;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147 HUMAN|HGNC=6301|UniProtKB=Q9ULS6 Q9ULS6 KCNS2 PTHR11537:SF60 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY S MEMBER 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;monovalent inorganic cation transport#GO:0015672;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;ion transport#GO:0006811;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;regulation of ion transport#GO:0043269 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=13788|UniProtKB=Q7Z3H0 Q7Z3H0 ANKRD33 PTHR24173:SF29 FAMILY NOT NAMED PHOTORECEPTOR ANKYRIN REPEAT PROTEIN HUMAN|HGNC=30926|UniProtKB=Q8N5C7 Q8N5C7 DTWD1 PTHR15627:SF8 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 1 HUMAN|HGNC=29913|UniProtKB=Q86WB0 Q86WB0 ZC3HC1 PTHR15835:SF6 NUCLEAR-INTERACTING PARTNER OF ALK NUCLEAR-INTERACTING PARTNER OF ALK membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=15772|UniProtKB=Q9Y6D6 Q9Y6D6 ARFGEF1 PTHR10663:SF137 GUANYL-NUCLEOTIDE EXCHANGE FACTOR BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=25267|UniProtKB=Q96LY2 Q96LY2 CCDC74B PTHR14882:SF7 COILED-COIL DOMAIN-CONTAINING 74A COILED-COIL DOMAIN-CONTAINING PROTEIN 74A-RELATED HUMAN|HGNC=8014|UniProtKB=P67809 P67809 YBX1 PTHR11544:SF68 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=2478|UniProtKB=Q15828 Q15828 CST6 PTHR47033:SF1 CYSTATIN-M CYSTATIN-M membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 HUMAN|HGNC=23826|UniProtKB=Q6ZMG9 Q6ZMG9 CERS6 PTHR12560:SF43 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 6 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=21601|UniProtKB=Q9H1N7 Q9H1N7 SLC35B3 PTHR10778:SF8 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=42400|UniProtKB=Q68D85 Q68D85 NCR3LG1 PTHR23411:SF27 TAPASIN NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3 LIGAND 1 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=27989|UniProtKB=Q5JQF8 Q5JQF8 PABPC1L2B PTHR24012:SF848 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1-LIKE 2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=8934|UniProtKB=Q9Y5J5 Q9Y5J5 PHLDA3 PTHR15478:SF5 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 3 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;signal transduction by p53 class mediator#GO:0072331;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;cell death#GO:0008219;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;intrinsic apoptotic signaling pathway#GO:0097193;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;protein kinase B signaling#GO:0043491;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;positive regulation of cell death#GO:0010942;regulation of protein kinase B signaling#GO:0051896 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|Ensembl=ENSG00000259680|UniProtKB=S4R3C0 S4R3C0 ENSG00000259680 PTHR23266:SF302 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=348|UniProtKB=P35869 P35869 AHR PTHR10649:SF9 ARYL HYDROCARBON RECEPTOR ARYL HYDROCARBON RECEPTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=15782|UniProtKB=Q3KRB8 Q3KRB8 ARHGAP11B PTHR15670:SF4 RHO GTPASE ACTIVATING PROTEIN 11A RHO GTPASE-ACTIVATING PROTEIN 11A-RELATED GTPase-activating protein#PC00257 HUMAN|HGNC=9053|UniProtKB=Q03405 Q03405 PLAUR PTHR10624:SF6 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR-RELATED UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Plasminogen activating cascade#P00050>uPAR#P01256;Blood coagulation#P00011>uPAR#P00433 HUMAN|HGNC=6348|UniProtKB=O43474 O43474 KLF4 PTHR23235:SF117 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 CCKR signaling map#P06959>KLF4#P07227 HUMAN|HGNC=9533|UniProtKB=P25789 P25789 PSMA4 PTHR11599:SF13 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-4 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome core complex, alpha-subunit complex#GO:0019773;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=12880|UniProtKB=Q8IYN0 Q8IYN0 ZNF100 PTHR24384:SF131 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 100-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=19168|UniProtKB=Q9GZM7 Q9GZM7 TINAGL1 PTHR12411:SF270 CYSTEINE PROTEASE FAMILY C1-RELATED TUBULOINTERSTITIAL NEPHRITIS ANTIGEN-LIKE cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=20797|UniProtKB=Q53TN4 Q53TN4 CYBRD1 PTHR10106:SF12 CYTOCHROME B561-RELATED CYTOCHROME B REDUCTASE 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198 HUMAN|HGNC=16297|UniProtKB=Q9UBR1 Q9UBR1 UPB1 PTHR43674:SF2 NITRILASE C965.09-RELATED BETA-UREIDOPROPIONASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 hydrolase#PC00121 Pyrimidine Metabolism#P02771>Beta-Ureidopropionase#P03127 HUMAN|HGNC=3065|UniProtKB=Q9Y6W6 Q9Y6W6 DUSP10 PTHR10159:SF299 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 10 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;negative regulation of MAPK cascade#GO:0043409;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;JNK cascade#GO:0007254;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;stress-activated protein kinase signaling cascade#GO:0031098;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;negative regulation of MAP kinase activity#GO:0043407;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131;p38 MAPK pathway#P05918>MKP5#P05921 HUMAN|HGNC=262|UniProtKB=P30542 P30542 ADORA1 PTHR24246:SF1 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR A1 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 HUMAN|HGNC=7959|UniProtKB=Q99463 Q99463 NPY6R PTHR24235:SF16 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 6-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=10057|UniProtKB=O43567 O43567 RNF13 PTHR22765:SF34 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF13 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=675|UniProtKB=Q13017 Q13017 ARHGAP5 PTHR46005:SF2 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 5 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=28715|UniProtKB=Q8IVB5 Q8IVB5 LIX1L PTHR31139:SF3 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG LIX1-LIKE PROTEIN process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagosome maturation#GO:0097352;cellular process#GO:0009987;autophagy#GO:0006914;cellular catabolic process#GO:0044248;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=23842|UniProtKB=Q8N961 Q8N961 ABTB2 PTHR46071:SF3 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6041|UniProtKB=A1L0T0 A1L0T0 ILVBL PTHR18968:SF166 THIAMINE PYROPHOSPHATE ENZYMES 2-HYDROXYACYL-COA LYASE 2 nucleotide binding#GO:0000166;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;branched-chain amino acid biosynthetic process#GO:0009082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 Isoleucine biosynthesis#P02748>Acetolactate synthase#P02997;Valine biosynthesis#P02785>Acetolactate synthase#P03216 HUMAN|HGNC=31948|UniProtKB=Q2WEN9 Q2WEN9 CEACAM16 PTHR44427:SF10 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 16 HUMAN|HGNC=20351|UniProtKB=Q96DC9 Q96DC9 OTUB2 PTHR12931:SF3 UBIQUITIN THIOLESTERASE PROTEIN OTUB UBIQUITIN THIOESTERASE OTUB2 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;ubiquitin-like protein-specific protease activity#GO:0019783;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin binding#GO:0043130;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;negative regulation of response to DNA damage stimulus#GO:2001021;regulation of double-strand break repair#GO:2000779;regulation of protein modification process#GO:0031399;regulation of response to DNA damage stimulus#GO:2001020;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;regulation of chromatin organization#GO:1902275;histone ubiquitination#GO:0016574;negative regulation of cellular component organization#GO:0051129;cellular protein metabolic process#GO:0044267;negative regulation of DNA metabolic process#GO:0051053;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;protein K48-linked deubiquitination#GO:0071108;histone modification#GO:0016570;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;chromosome organization#GO:0051276;negative regulation of protein ubiquitination#GO:0031397;regulation of cellular process#GO:0050794;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;negative regulation of DNA repair#GO:0045738;protein modification process#GO:0036211;regulation of histone modification#GO:0031056;regulation of DNA repair#GO:0006282;organic cyclic compound metabolic process#GO:1901360;negative regulation of organelle organization#GO:0010639;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;histone H2A ubiquitination#GO:0033522;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of double-strand break repair#GO:2000780;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;protein K63-linked ubiquitination#GO:0070534;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=11404|UniProtKB=O00506 O00506 STK25 PTHR48012:SF9 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE/THREONINE-PROTEIN KINASE 25 HUMAN|HGNC=20995|UniProtKB=Q9Y294 Q9Y294 ASF1A PTHR12040:SF8 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1A protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;organelle organization#GO:0006996;chromosome organization#GO:0051276;chromatin organization#GO:0006325;DNA replication-independent nucleosome organization#GO:0034724;protein-containing complex subunit organization#GO:0043933 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=4175|UniProtKB=P50440 P50440 GATM PTHR10488:SF1 GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL GLYCINE AMIDINOTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transferase#PC00220 HUMAN|HGNC=13411|UniProtKB=Q8N3S3 Q8N3S3 PHTF2 PTHR12680:SF2 PUTATIVE HOMEODOMAIN TRANSCRIPTION FACTOR PHTF HOMEODOMAIN TRANSCRIPTION FACTOR 2-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=15856|UniProtKB=Q9Y2B4 Q9Y2B4 TP53TG5 PTHR15562:SF0 TP53-TARGET GENE 5 PROTEIN TP53-TARGET GENE 5 PROTEIN HUMAN|HGNC=19278|UniProtKB=Q9H1E1 Q9H1E1 RNASE7 PTHR11437:SF31 RIBONUCLEASE RIBONUCLEASE 7 HUMAN|HGNC=6562|UniProtKB=P05162 P05162 LGALS2 PTHR11346:SF104 GALECTIN GALECTIN-2 extracellular matrix binding#GO:0050840;protein binding#GO:0005515;carbohydrate binding#GO:0030246;binding#GO:0005488 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=11590|UniProtKB=Q16650 Q16650 TBR1 PTHR11267:SF88 T-BOX PROTEIN-RELATED T-BOX BRAIN PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 specification of symmetry#GO:0009799;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;central nervous system neuron differentiation#GO:0021953;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;heart looping#GO:0001947;central nervous system development#GO:0007417;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular nitrogen compound metabolic process#GO:0034641;cell fate commitment#GO:0045165;regulation of neuron differentiation#GO:0045664;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;embryonic organ development#GO:0048568;forebrain development#GO:0030900;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;head development#GO:0060322;heart development#GO:0007507;embryonic heart tube development#GO:0035050;neurogenesis#GO:0022008;determination of heart left/right asymmetry#GO:0061371;RNA metabolic process#GO:0016070;epithelium development#GO:0060429;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;determination of bilateral symmetry#GO:0009855;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cell fate specification#GO:0001708;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;determination of left/right symmetry#GO:0007368;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=25297|UniProtKB=Q6ZN04 Q6ZN04 MEX3B PTHR23285:SF5 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3B RNA metabolism protein#PC00031 HUMAN|HGNC=26230|UniProtKB=Q53R12 Q53R12 TM4SF20 PTHR14198:SF17 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 20 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=18189|UniProtKB=Q9NPD3 Q9NPD3 EXOSC4 PTHR11953:SF0 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP41 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;aromatic compound catabolic process#GO:0019439;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;nucleobase-containing compound catabolic process#GO:0034655;organic substance catabolic process#GO:1901575;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 exoribonuclease#PC00099 HUMAN|HGNC=11304|UniProtKB=P49458 P49458 SRP9 PTHR12834:SF12 SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;translation#GO:0006412;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;protein localization to endoplasmic reticulum#GO:0070972;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein targeting to ER#GO:0045047;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;amide biosynthetic process#GO:0043604;protein targeting to membrane#GO:0006612;peptide biosynthetic process#GO:0043043;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=3449|UniProtKB=O75460 O75460 ERN1 PTHR13954:SF17 IRE1-RELATED SERINE/THREONINE-PROTEIN KINASE/ENDORIBONUCLEASE IRE1 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;unfolded protein binding#GO:0051082;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to unfolded protein#GO:0006986;response to topologically incorrect protein#GO:0035966;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;signaling#GO:0023052 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 endoribonuclease#PC00094 Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110;Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125 HUMAN|HGNC=29168|UniProtKB=Q68CZ1 Q68CZ1 RPGRIP1L PTHR14240:SF4 RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN PROTEIN FANTOM protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488 non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;sensory system development#GO:0048880;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;anatomical structure development#GO:0048856;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;animal organ development#GO:0048513;developmental process#GO:0032502;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;retina development in camera-type eye#GO:0060041;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;protein localization to organelle#GO:0033365;visual system development#GO:0150063;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cell development#GO:0048468;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;camera-type eye development#GO:0043010;generation of neurons#GO:0048699 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26121|UniProtKB=Q96EI5 Q96EI5 TCEAL4 PTHR14754:SF10 TRANSCRIPTION ELONGATION FACTOR A TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 4 general transcription factor#PC00259 HUMAN|HGNC=8714|UniProtKB=Q9Y5F8 Q9Y5F8 PCDHGB7 PTHR24028:SF113 CADHERIN-87A PROTOCADHERIN GAMMA-B7 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=27506|UniProtKB=Q8NBE8 Q8NBE8 KLHL23 PTHR24412:SF304 KELCH PROTEIN KELCH-LIKE PROTEIN 23 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6003|UniProtKB=Q9UHF4 Q9UHF4 IL20RA PTHR20859:SF53 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-20 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=17663|UniProtKB=Q5JRX3 Q5JRX3 PITRM1 PTHR43016:SF13 PRESEQUENCE PROTEASE PRESEQUENCE PROTEASE, MITOCHONDRIAL hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153 HUMAN|HGNC=4621|UniProtKB=P15170 P15170 GSPT1 PTHR23115:SF125 TRANSLATION FACTOR EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR GTP-BINDING SUBUNIT ERF3A GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111 sulfur compound metabolic process#GO:0006790;cellular protein complex disassembly#GO:0043624;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;translational termination#GO:0006415;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 translation factor#PC00223 HUMAN|HGNC=28228|UniProtKB=Q96DD0 Q96DD0 LRRC39 PTHR45752:SF6 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 39 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|HGNC=5426|UniProtKB=P01569 P01569 IFNA5 PTHR11691:SF60 TYPE I INTERFERON INTERFERON ALPHA-5 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=25873|UniProtKB=Q9H7X2 Q9H7X2 C1orf115 PTHR14680:SF1 SI:DKEY-126G1.9-RELATED SI:DKEY-126G1.9-RELATED HUMAN|HGNC=14604|UniProtKB=Q9BXJ7 Q9BXJ7 AMN PTHR14995:SF2 AMNIONLESS PROTEIN AMNIONLESS macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898 intracellular vesicle#GO:0097708;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;cytoplasm#GO:0005737;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 HUMAN|HGNC=15373|UniProtKB=Q8NGB6 Q8NGB6 OR4M2 PTHR48002:SF103 OLFACTORY RECEPTOR G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=17290|UniProtKB=Q6UWB1 Q6UWB1 IL27RA PTHR23036:SF6 CYTOKINE RECEPTOR INTERLEUKIN-27 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;growth factor receptor binding#GO:0070851;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to cytokine#GO:0034097;regulation of cell-cell adhesion#GO:0022407;biological adhesion#GO:0022610;positive regulation of cell population proliferation#GO:0008284;positive regulation of T cell proliferation#GO:0042102;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;leukocyte cell-cell adhesion#GO:0007159;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;T cell proliferation#GO:0042098;positive regulation of leukocyte cell-cell adhesion#GO:1903039;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of immune system process#GO:0002682;cytokine-mediated signaling pathway#GO:0019221;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;mononuclear cell proliferation#GO:0032943;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;cellular response to organic substance#GO:0071310;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular process#GO:0009987;regulation of T cell proliferation#GO:0042129;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;positive regulation of cell adhesion#GO:0045785;regulation of leukocyte proliferation#GO:0070663;positive regulation of cell activation#GO:0050867;positive regulation of cell-cell adhesion#GO:0022409 membrane protein complex#GO:0098796;leaflet of membrane bilayer#GO:0097478;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;side of membrane#GO:0098552;external side of plasma membrane#GO:0009897;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=33895|UniProtKB=Q6S8J3 Q6S8J3 POTEE PTHR24118:SF94 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER E-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=35167|UniProtKB=A7E2S9 A7E2S9 ANKRD30BL PTHR24147:SF54 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 30B-LIKE-RELATED HUMAN|HGNC=10929|UniProtKB=Q14916 Q14916 SLC17A1 PTHR11662:SF26 SOLUTE CARRIER FAMILY 17 SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 secondary carrier transporter#PC00258 Ionotropic glutamate receptor pathway#P00037>Vglut#P01021 HUMAN|HGNC=9193|UniProtKB=P61218 P61218 POLR2F PTHR10773:SF12 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 HUMAN|HGNC=10368|UniProtKB=P62917 P62917 RPL8 PTHR13691:SF16 RIBOSOMAL PROTEIN L2 60S RIBOSOMAL PROTEIN L8 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=24851|UniProtKB=A6NMB1 A6NMB1 SIGLEC16 PTHR12035:SF96 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 16 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=30209|UniProtKB=Q8IVA1 Q8IVA1 PCP2 PTHR47503:SF1 PURKINJE CELL PROTEIN 2 PURKINJE CELL PROTEIN 2 HOMOLOG HUMAN|HGNC=11303|UniProtKB=O76094 O76094 SRP72 PTHR14094:SF9 SIGNAL RECOGNITION PARTICLE 72 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;translation#GO:0006412;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein localization to organelle#GO:0033365;cellular protein metabolic process#GO:0044267;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;protein localization to endoplasmic reticulum#GO:0070972;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;amide biosynthetic process#GO:0043604;protein targeting to membrane#GO:0006612;peptide biosynthetic process#GO:0043043;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=2318|UniProtKB=Q9HCH3 Q9HCH3 CPNE5 PTHR10857:SF51 COPINE COPINE-5 calcium-dependent phospholipid binding#GO:0005544;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;binding#GO:0005488 response to metal ion#GO:0010038;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=28824|UniProtKB=A0A0J9YX57 A0A0J9YX57 MAGEB6B PTHR11736:SF67 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MAGE DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=39755|UniProtKB=E2RYF6 E2RYF6 MUC22 PTHR37000:SF3 MUCIN-22 MUCIN-22 HUMAN|HGNC=29387|UniProtKB=Q6NSI8 Q6NSI8 KIAA1841 PTHR20946:SF0 UNCHARACTERIZED DUF3342 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=24576|UniProtKB=Q9H211 Q9H211 CDT1 PTHR28637:SF13 DNA REPLICATION FACTOR CDT1 DNA REPLICATION FACTOR CDT1 enzyme binding#GO:0019899;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;nuclear DNA replication#GO:0033260;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;DNA replication initiation#GO:0006270;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;DNA replication checkpoint#GO:0000076;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;DNA replication#GO:0006260;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 HUMAN|HGNC=11161|UniProtKB=P62304 P62304 SNRPE PTHR11193:SF9 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=6734|UniProtKB=P12980 P12980 LYL1 PTHR13864:SF6 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED PROTEIN LYL-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=19847|UniProtKB=P0C221 P0C221 CCDC175 PTHR35347:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 175 COILED-COIL DOMAIN-CONTAINING PROTEIN 175 HUMAN|HGNC=10386|UniProtKB=P62277 P62277 RPS13 PTHR11885:SF20 RIBOSOMAL PROTEIN S15P/S13E 40S RIBOSOMAL PROTEIN S13 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 membrane-enclosed lumen#GO:0031974;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;small ribosomal subunit#GO:0015935;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=17086|UniProtKB=Q9H0L4 Q9H0L4 CSTF2T PTHR45735:SF3 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 TAU VARIANT nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=13237|UniProtKB=Q9UK28 Q9UK28 TMEM59L PTHR28652:SF1 TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN TRANSMEMBRANE PROTEIN 59-LIKE HUMAN|HGNC=11020|UniProtKB=O95436 O95436 SLC34A2 PTHR10010:SF23 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;solute:cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;inorganic anion transport#GO:0015698 microvillus#GO:0005902;supramolecular complex#GO:0099080;brush border#GO:0005903;actin filament bundle#GO:0032432;cluster of actin-based cell projections#GO:0098862;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=10401|UniProtKB=P62269 P62269 RPS18 PTHR10871:SF35 30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18 40S RIBOSOMAL PROTEIN S18 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=1738|UniProtKB=Q9Y5S2 Q9Y5S2 CDC42BPB PTHR22988:SF34 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE/THREONINE-PROTEIN KINASE MRCK BETA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;actomyosin structure organization#GO:0031032;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;actin cytoskeleton organization#GO:0030036;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=26091|UniProtKB=Q53H54 Q53H54 TRMT12 PTHR23245:SF25 TRNA METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA methyltransferase#PC00033 HUMAN|HGNC=14373|UniProtKB=Q92990 Q92990 GLMN PTHR15430:SF1 GLOMULIN GLOMULIN transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;molecular function regulator#GO:0098772;enzyme inhibitor activity#GO:0004857;catalytic activity, acting on a protein#GO:0140096;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=5192|UniProtKB=Q14469 Q14469 HES1 PTHR10985:SF77 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR HES-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 HUMAN|HGNC=44666|UniProtKB=H3BNL1 H3BNL1 C3orf84 PTHR35539:SF1 CDNA SEQUENCE BC048562 HDNR DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=8883|UniProtKB=O94921 O94921 CDK14 PTHR24056:SF154 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 14 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=4502|UniProtKB=Q9Y5Y4 Q9Y5Y4 PTGDR2 PTHR24229:SF8 NEUROPEPTIDES RECEPTOR PROSTAGLANDIN D2 RECEPTOR 2 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=28739|UniProtKB=Q8IXQ9 Q8IXQ9 ETFBKMT PTHR43648:SF1 ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE methyltransferase#PC00155 HUMAN|HGNC=16771|UniProtKB=Q8IUG1 Q8IUG1 KRTAP1-3 PTHR23262:SF216 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 1-3 HUMAN|HGNC=23161|UniProtKB=Q9BVK2 Q9BVK2 ALG8 PTHR12413:SF2 DOLICHYL GLYCOSYLTRANSFERASE DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE-RELATED transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular lipid metabolic process#GO:0044255;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 HUMAN|HGNC=21077|UniProtKB=Q8N1G2 Q8N1G2 CMTR1 PTHR16121:SF0 UNCHARACTERIZED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;macromolecule methylation#GO:0043414;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=27277|UniProtKB=A6NF34 A6NF34 ANTXRL PTHR16059:SF16 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR-LIKE cell adhesion molecule#PC00069 HUMAN|Ensembl=ENSG00000275993|UniProtKB=A0A0B4J2F2 A0A0B4J2F2 SIK1B PTHR24343:SF204 SERINE/THREONINE KINASE SERINE/THREONINE-PROTEIN KINASE SIK1-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=10464|UniProtKB=Q15404 Q15404 RSU1 PTHR45752:SF156 LEUCINE-RICH REPEAT-CONTAINING RAS SUPPRESSOR PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3296|UniProtKB=Q04637 Q04637 EIF4G1 PTHR23253:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1 translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=10724|UniProtKB=Q13214 Q13214 SEMA3B PTHR11036:SF37 SEMAPHORIN SEMAPHORIN-3B receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=43638|UniProtKB=A8MW99 A8MW99 MEI4 PTHR28575:SF1 MEIOSIS-SPECIFIC PROTEIN MEI4 MEIOSIS-SPECIFIC PROTEIN MEI4 cellular aromatic compound metabolic process#GO:0006725;male gamete generation#GO:0048232;homologous chromosome segregation#GO:0045143;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;meiotic telophase I#GO:0007134;developmental process#GO:0032502;cell cycle process#GO:0022402;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;cell differentiation#GO:0030154;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle phase#GO:0022403;multi-organism reproductive process#GO:0044703;meiosis I#GO:0007127;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;germ cell development#GO:0007281;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;nuclear chromosome segregation#GO:0098813;meiosis I cell cycle phase#GO:0098764;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;multi-organism process#GO:0051704;primary metabolic process#GO:0044238;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;meiotic DNA double-strand break formation#GO:0042138;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;cell cycle#GO:0007049;biological phase#GO:0044848;multicellular organismal process#GO:0032501;organelle fission#GO:0048285 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=26658|UniProtKB=Q8NA72 Q8NA72 POC5 PTHR28618:SF1 CENTROSOMAL PROTEIN POC5 CENTROSOMAL PROTEIN POC5 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=15180|UniProtKB=Q8NGL7 Q8NGL7 OR4P4 PTHR48002:SF101 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4P4 transmembrane signal receptor#PC00197 HUMAN|HGNC=18188|UniProtKB=Q9UM00 Q9UM00 TMCO1 PTHR20917:SF0 PNAS-RELATED CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=28299|UniProtKB=Q6NUT3 Q6NUT3 MFSD12 PTHR11328:SF28 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 12 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;transport#GO:0006810 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=21424|UniProtKB=Q96LB3 Q96LB3 IFT74 PTHR31432:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=17494|UniProtKB=Q5T442 Q5T442 GJC2 PTHR11984:SF52 CONNEXIN GAP JUNCTION GAMMA-2 PROTEIN gap junction#PC00105 HUMAN|HGNC=18264|UniProtKB=Q8NEY4 Q8NEY4 ATP6V1C2 PTHR10137:SF4 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002 HUMAN|HGNC=19088|UniProtKB=Q9NR48 Q9NR48 ASH1L PTHR46147:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L histone modifying enzyme#PC00261 HUMAN|HGNC=21392|UniProtKB=Q96DU3 Q96DU3 SLAMF6 PTHR12080:SF16 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 6 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=13530|UniProtKB=Q9Y2B1 Q9Y2B1 RXYLT1 PTHR15576:SF1 RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1 RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1 UDP-xylosyltransferase activity#GO:0035252;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;xylosyltransferase activity#GO:0042285;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=49288|UniProtKB=A8MTT3 A8MTT3 CEBPZOS PTHR38001:SF1 PROTEIN CEBPZOS PROTEIN CEBPZOS HUMAN|HGNC=25991|UniProtKB=Q6NUM9 Q6NUM9 RETSAT PTHR46091:SF1 BLR7054 PROTEIN ALL-TRANS-RETINOL 13,14-REDUCTASE HUMAN|HGNC=7136|UniProtKB=P42568 P42568 MLLT3 PTHR23195:SF25 YEATS DOMAIN PROTEIN AF-9 general transcription factor#PC00259 HUMAN|HGNC=7963|UniProtKB=Q14995 Q14995 NR1D2 PTHR24082:SF112 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=24161|UniProtKB=Q9BTY7 Q9BTY7 HGH1 PTHR13387:SF9 PROTEIN HGH1 HOMOLOG PROTEIN HGH1 HOMOLOG HUMAN|Gene=YF016_HUMAN|UniProtKB=A6NL46 A6NL46 - PTHR11639:SF71 S100 CALCIUM-BINDING PROTEIN UPF0607 PROTEIN ENSP00000332738-RELATED protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=57|UniProtKB=O95255 O95255 ABCC6 PTHR24223:SF339 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 6 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|Ensembl=ENSG00000126500|UniProtKB=A0A6E1VY70 A0A6E1VY70 FLRT1 PTHR45712:SF15 AGAP008170-PA LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=26432|UniProtKB=Q8IVP9 Q8IVP9 ZNF547 PTHR24377:SF808 IP01015P-RELATED ZINC FINGER PROTEIN 547 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19032|UniProtKB=Q9BU76 Q9BU76 MMTAG2 PTHR14580:SF0 MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 FAMILY MEMBER MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 HUMAN|HGNC=25403|UniProtKB=Q6UVJ0 Q6UVJ0 SASS6 PTHR44281:SF2 SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG HUMAN|HGNC=7380|UniProtKB=P26927 P26927 MST1 PTHR24261:SF12 PLASMINOGEN-RELATED HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 HUMAN|HGNC=17902|UniProtKB=Q9GZQ3 Q9GZQ3 COMMD5 PTHR15666:SF3 COMM DOMAIN CONTAINING PROTEIN 5 COMM DOMAIN-CONTAINING PROTEIN 5 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=15664|UniProtKB=Q9NYU1 Q9NYU1 UGGT2 PTHR11226:SF1 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 2 transferase activity, transferring hexosyl groups#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;unfolded protein binding#GO:0051082;binding#GO:0005488;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;protein binding#GO:0005515;glucosyltransferase activity#GO:0046527;transferase activity, transferring glycosyl groups#GO:0016757 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;cellular response to misfolded protein#GO:0071218;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to endoplasmic reticulum stress#GO:0034976;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;cellular response to organic substance#GO:0071310;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;protein N-linked glycosylation#GO:0006487;response to topologically incorrect protein#GO:0035966;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;glycosylation#GO:0070085 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=15684|UniProtKB=Q9BYG0 Q9BYG0 B3GNT5 PTHR11214:SF21 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE LACTOSYLCERAMIDE 1,3-N-ACETYL-BETA-D-GLUCOSAMINYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;head development#GO:0060322;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;developmental process#GO:0032502;brain development#GO:0007420;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nervous system development#GO:0007399;system development#GO:0048731;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;central nervous system development#GO:0007417;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;multicellular organism development#GO:0007275;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;cellular polysaccharide biosynthetic process#GO:0033692;glycosylation#GO:0070085;cellular polysaccharide metabolic process#GO:0044264 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=28455|UniProtKB=Q9H9R9 Q9H9R9 DBNDD1 PTHR16294:SF4 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN DOMAIN-CONTAINING PROTEIN 1 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;negative regulation of protein kinase activity#GO:0006469;negative regulation of transferase activity#GO:0051348;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;negative regulation of cellular process#GO:0048523;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;protein phosphorylation#GO:0006468;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=7516|UniProtKB=Q9HC84 Q9HC84 MUC5B PTHR11339:SF269 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-5B extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=21353|UniProtKB=Q9H511 Q9H511 KLHL31 PTHR45632:SF17 LD33804P KELCH-LIKE PROTEIN 31 HUMAN|HGNC=2021|UniProtKB=P51790 P51790 CLCN3 PTHR45711:SF8 CHLORIDE CHANNEL PROTEIN H(+)/CL(-) EXCHANGE TRANSPORTER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;antiporter activity#GO:0015297;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;solute:cation antiporter activity#GO:0015298;gated channel activity#GO:0022836;proton transmembrane transporter activity#GO:0015078;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;solute:proton antiporter activity#GO:0015299;active ion transmembrane transporter activity#GO:0022853 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;Golgi apparatus#GO:0005794;early endosome#GO:0005769;cell junction#GO:0030054;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;intrinsic component of plasma membrane#GO:0031226;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=24290|UniProtKB=Q8TDX6 Q8TDX6 CSGALNACT1 PTHR12369:SF19 CHONDROITIN SYNTHASE CHONDROITIN SULFATE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 HUMAN|HGNC=16211|UniProtKB=Q9UJQ7 Q9UJQ7 SCP2D1 PTHR24314:SF20 NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED NON-SPECIFIC LIPID-TRANSFER PROTEIN-RELATED transfer/carrier protein#PC00219 HUMAN|HGNC=21870|UniProtKB=Q9NV12 Q9NV12 TMEM140 PTHR16103:SF0 TRANSMEMBRANE PROTEIN 140 TRANSMEMBRANE PROTEIN 140 HUMAN|HGNC=21690|UniProtKB=Q7L5D6 Q7L5D6 GET4 PTHR12875:SF0 UNCHARACTERIZED GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=3005|UniProtKB=O60762 O60762 DPM1 PTHR43398:SF1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 glycosyltransferase#PC00111 HUMAN|HGNC=8675|UniProtKB=Q9Y5H5 Q9Y5H5 PCDHA9 PTHR24028:SF255 CADHERIN-87A PROTOCADHERIN ALPHA-9 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=1701|UniProtKB=P60033 P60033 CD81 PTHR19282:SF214 TETRASPANIN CD81 ANTIGEN intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=17005|UniProtKB=O75829 O75829 CNMD PTHR14064:SF6 CHONDROMODULIN-RELATED LEUKOCYTE CELL-DERIVED CHEMOTAXIN 1 negative regulation of cellular response to growth factor stimulus#GO:0090288;cell population proliferation#GO:0008283;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;epithelial cell proliferation#GO:0050673;regulation of cellular response to growth factor stimulus#GO:0090287;vasculature development#GO:0001944;negative regulation of cell communication#GO:0010648;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;tube development#GO:0035295;cell communication#GO:0007154;regulation of response to stimulus#GO:0048583;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;epithelium development#GO:0060429;regulation of anatomical structure morphogenesis#GO:0022603;regulation of signaling#GO:0023051;developmental process#GO:0032502;endothelial cell proliferation#GO:0001935;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;system development#GO:0048731;negative regulation of cell population proliferation#GO:0008285;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;cell morphogenesis involved in differentiation#GO:0000904;negative regulation of response to stimulus#GO:0048585;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;cell development#GO:0048468;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 HUMAN|HGNC=27022|UniProtKB=Q8TCW7 Q8TCW7 ZPLD1 PTHR14002:SF24 ENDOGLIN/TGF-BETA RECEPTOR TYPE III ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=13825|UniProtKB=Q9BZE9 Q9BZE9 ASPSCR1 PTHR46467:SF1 TETHER CONTAINING UBX DOMAIN FOR GLUT4 TETHER CONTAINING UBX DOMAIN FOR GLUT4 HUMAN|HGNC=20365|UniProtKB=Q9C0C6 Q9C0C6 CIPC PTHR34648:SF1 CLOCK-INTERACTING PACEMAKER CLOCK-INTERACTING PACEMAKER negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=29089|UniProtKB=Q5T8A7 Q5T8A7 PPP1R26 PTHR15724:SF0 UNCHARACTERIZED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 26 HUMAN|HGNC=18986|UniProtKB=Q9HCG7 Q9HCG7 GBA2 PTHR12654:SF0 BILE ACID BETA-GLUCOSIDASE-RELATED NON-LYSOSOMAL GLUCOSYLCERAMIDASE glucosidase#PC00108 HUMAN|HGNC=14259|UniProtKB=Q9ULW5 Q9ULW5 RAB26 PTHR47978:SF21 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-26 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=33499|UniProtKB=Q8WXE1 Q8WXE1 ATRIP PTHR28594:SF1 ATR-INTERACTING PROTEIN ATR-INTERACTING PROTEIN HUMAN|HGNC=5360|UniProtKB=P41134 P41134 ID1 PTHR11723:SF4 DNA-BINDING PROTEIN INHIBITOR DNA-BINDING PROTEIN INHIBITOR ID-1 molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=10023|UniProtKB=Q92963 Q92963 RIT1 PTHR24070:SF208 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RIT1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=8527|UniProtKB=P55809 P55809 OXCT1 PTHR13707:SF30 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID COENZYME A TRANSFERASE 1, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transferase#PC00220 HUMAN|HGNC=9005|UniProtKB=Q99697 Q99697 PITX2 PTHR45882:SF4 PITUITARY HOMEOBOX HOMOLOG PTX1 PITUITARY HOMEOBOX 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>PITX#P06722 HUMAN|HGNC=1606|UniProtKB=P51681 P51681 CCR5 PTHR10489:SF686 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 5 response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response#GO:0006952;immune response#GO:0006955;inflammatory response#GO:0006954 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=15930|UniProtKB=Q9NR83 Q9NR83 SLC2A4RG PTHR13006:SF8 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 SLC2A4 REGULATOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=25741|UniProtKB=Q9BS31 Q9BS31 ZNF649 PTHR24404:SF34 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 649 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29577|UniProtKB=Q8WVE7 Q8WVE7 TMEM170A PTHR22779:SF2 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 170A HUMAN|HGNC=16982|UniProtKB=Q9Y4C4 Q9Y4C4 MFHAS1 PTHR45752:SF48 LEUCINE-RICH REPEAT-CONTAINING MALIGNANT FIBROUS HISTIOCYTOMA-AMPLIFIED SEQUENCE 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11042|UniProtKB=P30531 P30531 SLC6A1 PTHR11616:SF138 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;neurotransmitter binding#GO:0042165;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 cell surface#GO:0009986;neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=15897|UniProtKB=Q5TEA6 Q5TEA6 SEL1L2 PTHR11102:SF53 SEL-1-LIKE PROTEIN PROTEIN SEL-1 HOMOLOG 2 HUMAN|HGNC=13533|UniProtKB=Q9NTI2 Q9NTI2 ATP8A2 PTHR24092:SF98 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IB pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=26509|UniProtKB=Q8N4B1 Q8N4B1 PHETA1 PTHR22902:SF17 SESQUIPEDALIAN SESQUIPEDALIAN-1 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;endocytosis#GO:0006897;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;early endosome#GO:0005769;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=26457|UniProtKB=Q96N22 Q96N22 ZNF681 PTHR24377:SF356 IP01015P-RELATED ZINC FINGER PROTEIN 681 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2252|UniProtKB=P31146 P31146 CORO1A PTHR10856:SF18 CORONIN CORONIN-1A cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 non-motor actin binding protein#PC00165 HUMAN|HGNC=32406|UniProtKB=Q1A5X6 Q1A5X6 IQCJ PTHR35976:SF1 IQ DOMAIN-CONTAINING PROTEIN J IQ DOMAIN-CONTAINING PROTEIN J HUMAN|HGNC=14637|UniProtKB=Q86UK0 Q86UK0 ABCA12 PTHR19229:SF29 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 12 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;signaling receptor binding#GO:0005102;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=3240|UniProtKB=Q06889 Q06889 EGR3 PTHR23235:SF78 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15355|UniProtKB=Q8NGC6 Q8NGC6 OR4K17 PTHR48002:SF34 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K17 transmembrane signal receptor#PC00197 HUMAN|HGNC=26839|UniProtKB=Q2M5E4 Q2M5E4 RGS21 PTHR10845:SF160 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 21 GTPase-activating protein#PC00257 HUMAN|HGNC=30575|UniProtKB=Q6IA17 Q6IA17 SIGIRR PTHR11890:SF19 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER SINGLE IG IL-1-RELATED RECEPTOR transmembrane signal receptor#PC00197 HUMAN|HGNC=12009|UniProtKB=P60174 P60174 TPI1 PTHR21139:SF24 TRIOSEPHOSPHATE ISOMERASE TRIOSEPHOSPHATE ISOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;nitrogen compound metabolic process#GO:0006807;cellular carbohydrate catabolic process#GO:0044275;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;carbohydrate biosynthetic process#GO:0016051;oxoacid metabolic process#GO:0043436;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glucose metabolic process#GO:0006006;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 isomerase#PC00135 Glycolysis#P00024>Triosephosphate isomerase#P00673 HUMAN|HGNC=21461|UniProtKB=Q9HBD1 Q9HBD1 RC3H2 PTHR13139:SF2 RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN ROQUIN-2 HUMAN|HGNC=10887|UniProtKB=Q15475 Q15475 SIX1 PTHR10390:SF13 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 HUMAN|HGNC=11925|UniProtKB=P50591 P50591 TNFSF10 PTHR11471:SF27 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10 Apoptosis signaling pathway#P00006>TRAIL#P00263 HUMAN|HGNC=5798|UniProtKB=A0A0A0MRZ7 A0A0A0MRZ7 IGKV2D-26 PTHR23267:SF361 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2D-26 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=12139|UniProtKB=A0A0B4J263 A0A0B4J263 TRAV39 PTHR19433:SF114 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 20-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=12201|UniProtKB=A0A0A0MS06 A0A0A0MS06 TRBV23-1 PTHR23268:SF82 T-CELL RECEPTOR BETA CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=6691|UniProtKB=O75427 O75427 LRCH4 PTHR16083:SF9 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 4 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229;PML body#GO:0016605 HUMAN|HGNC=970|UniProtKB=Q8N3I7 Q8N3I7 BBS5 PTHR21351:SF0 BARDET-BIEDL SYNDROME PROTEIN 5 BARDET-BIEDL SYNDROME 5 PROTEIN phosphatidylinositol-3-phosphate binding#GO:0032266;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;BBSome#GO:0034464;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=4764|UniProtKB=P84243 P84243 H3-3B PTHR11426:SF228 HISTONE H3 HISTONE H3.3-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 histone#PC00118 DNA replication#P00017>Histones#P00527 HUMAN|HGNC=20359|UniProtKB=Q6ZU80 Q6ZU80 CEP128 PTHR46657:SF1 CENTROSOMAL PROTEIN OF 128 KDA CENTROSOMAL PROTEIN OF 128 KDA HUMAN|HGNC=8060|UniProtKB=P49757 P49757 NUMB PTHR11232:SF33 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN NUMB HOMOLOG cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 Notch signaling pathway#P00045>Numb#P01118 HUMAN|HGNC=28313|UniProtKB=O43151 O43151 TET3 PTHR23358:SF4 UNCHARACTERIZED METHYLCYTOSINE DIOXYGENASE TET3 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;demethylation#GO:0070988;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;oxidative demethylation#GO:0070989;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26475|UniProtKB=Q1RMZ1 Q1RMZ1 BMT2 PTHR21008:SF0 UNCHARACTERIZED S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1 catalytic activity, acting on RNA#GO:0140098;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=21386|UniProtKB=Q8N475 Q8N475 FSTL5 PTHR10913:SF44 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 5 multicellular organismal process#GO:0032501;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 protease inhibitor#PC00191 HUMAN|HGNC=21033|UniProtKB=Q8IYU2 Q8IYU2 HACE1 PTHR11254:SF363 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HACE1 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=21905|UniProtKB=Q9NXC5 Q9NXC5 MIOS PTHR16453:SF9 WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER GATOR COMPLEX PROTEIN MIOS cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=14334|UniProtKB=Q969V6 Q969V6 MRTFA PTHR22793:SF6 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN-RELATED TRANSCRIPTION FACTOR A muscle structure development#GO:0061061;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;anatomical structure development#GO:0048856;developmental process#GO:0032502 DNA-binding transcription factor#PC00218 HUMAN|HGNC=11422|UniProtKB=A8MT69 A8MT69 CENPX PTHR28680:SF1 CENTROMERE PROTEIN X CENTROMERE PROTEIN X cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;meiotic chromosome separation#GO:0051307;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;cellular nitrogen compound biosynthetic process#GO:0044271;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;replication fork processing#GO:0031297;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;cellular macromolecule biosynthetic process#GO:0034645;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;DNA biosynthetic process#GO:0071897;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;aromatic compound biosynthetic process#GO:0019438;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;Fanconi anaemia nuclear complex#GO:0043240;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=15532|UniProtKB=Q9BX67 Q9BX67 JAM3 PTHR44598:SF2 JUNCTIONAL ADHESION MOLECULE C JUNCTIONAL ADHESION MOLECULE C HUMAN|Ensembl=ENSG00000281310|UniProtKB=A0A1W2PRG0 A0A1W2PRG0 ENSG00000281310 PTHR43917:SF13 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE THETA-4-RELATED transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=30219|UniProtKB=A6NM36 A6NM36 LRRC30 PTHR45752:SF35 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 30 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26273|UniProtKB=Q9H5H4 Q9H5H4 ZNF768 PTHR24381:SF280 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 768 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15020|UniProtKB=A6NH00 A6NH00 OR2T8 PTHR26453:SF286 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T33-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=17718|UniProtKB=P67812 P67812 SEC11A PTHR10806:SF36 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11A hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;signal peptide processing#GO:0006465;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 serine protease#PC00203 Endothelin signaling pathway#P00019>signal peptidase#P00573;Vasopressin synthesis#P04395>Signal Peptidase#P04589 HUMAN|HGNC=15550|UniProtKB=Q4LE39 Q4LE39 ARID4B PTHR13964:SF24 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=26449|UniProtKB=Q96N58 Q96N58 ZNF578 PTHR24377:SF859 IP01015P-RELATED ZINC FINGER PROTEIN 578 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16953|UniProtKB=Q15063 Q15063 POSTN PTHR10900:SF12 PERIOSTIN-RELATED PERIOSTIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;biological adhesion#GO:0022610 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cell adhesion molecule#PC00069 HUMAN|HGNC=16462|UniProtKB=Q96SI9 Q96SI9 STRBP PTHR45762:SF1 ZINC FINGER RNA-BINDING PROTEIN SPERMATID PERINUCLEAR RNA-BINDING PROTEIN nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;double-stranded RNA binding#GO:0003725;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=6211|UniProtKB=P23352 P23352 ANOS1 PTHR14131:SF5 ANOSMIN ANOSMIN-1 cellular developmental process#GO:0048869;system development#GO:0048731;cell differentiation#GO:0030154;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 extracellular matrix protein#PC00102 HUMAN|HGNC=30912|UniProtKB=Q96NZ8 Q96NZ8 WFIKKN1 PTHR45938:SF6 ACP24A4-RELATED KUNITZ-TYPE PROTEASE INHIBITOR 3-RELATED HUMAN|HGNC=5637|UniProtKB=A0A075B7E8 A0A075B7E8 IGHV3OR16-13 PTHR23266:SF290 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=5237|UniProtKB=P34932 P34932 HSPA4 PTHR45639:SF6 HSC70CB, ISOFORM G-RELATED HEAT SHOCK 70 KDA PROTEIN 4 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3619|UniProtKB=P08637 P08637 FCGR3A PTHR11481:SF103 IMMUNOGLOBULIN FC RECEPTOR LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR III-A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=4296|UniProtKB=P06280 P06280 GLA PTHR11452:SF14 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-GALACTOSIDASE A hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carbohydrate metabolic process#GO:0005975;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 galactosidase#PC00104 HUMAN|HGNC=19391|UniProtKB=O14543 O14543 SOCS3 PTHR10155:SF11 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phosphorylation#GO:0016310;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 HUMAN|HGNC=10847|UniProtKB=P57775 P57775 FBXW4 PTHR14381:SF1 DACTYLIN F-BOX/WD REPEAT-CONTAINING PROTEIN 4 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=18119|UniProtKB=Q8NB90 Q8NB90 SPATA5 PTHR23077:SF27 AAA-FAMILY ATPASE ATPASE FAMILY PROTEIN 2 HOMOLOG hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=1695|UniProtKB=P09564 P09564 CD7 PTHR15343:SF0 CD7 T-CELL ANTIGEN CD7 HUMAN|HGNC=53075|UniProtKB=P0DP42 P0DP42 TMEM225B PTHR36477:SF2 TRANSMEMBRANE PROTEIN 225 TRANSMEMBRANE PROTEIN 225B HUMAN|HGNC=5238|UniProtKB=P11021 P11021 HSPA5 PTHR19375:SF380 HEAT SHOCK PROTEIN 70KDA ENDOPLASMIC RETICULUM CHAPERONE BIP carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ATP binding#GO:0005524;ATPase activity#GO:0016887 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;chaperone-mediated protein folding#GO:0061077;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;ubiquitin-dependent ERAD pathway#GO:0030433;'de novo' protein folding#GO:0006458;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 HUMAN|HGNC=24951|UniProtKB=Q9GIP4 Q9GIP4 SLC7A5P2 PTHR11785:SF315 AMINO ACID TRANSPORTER L-TYPE AMINO ACID TRANSPORTER 1-LIKE PROTEIN IMAA-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 transporter#PC00227 HUMAN|HGNC=3173|UniProtKB=O43854 O43854 EDIL3 PTHR24543:SF283 MULTICOPPER OXIDASE-RELATED EGF-LIKE REPEAT AND DISCOIDIN I-LIKE DOMAIN-CONTAINING PROTEIN 3 oxidoreductase#PC00176 HUMAN|HGNC=12879|UniProtKB=P21506 P21506 ZNF10 PTHR24381:SF124 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 10 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23799|UniProtKB=Q8IYX4 Q8IYX4 DND1 PTHR21245:SF4 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN DEAD END PROTEIN HOMOLOG 1 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;posttranscriptional gene silencing#GO:0016441;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;gene silencing by miRNA#GO:0035195;negative regulation of cellular catabolic process#GO:0031330;gene silencing by RNA#GO:0031047;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=20088|UniProtKB=Q7Z601 Q7Z601 GPR142 PTHR46272:SF1 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTOR 142-RELATED HUMAN|HGNC=34295|UniProtKB=A6NML5 A6NML5 TMEM212 PTHR23320:SF156 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED TRANSMEMBRANE PROTEIN 212 transporter#PC00227 HUMAN|HGNC=18155|UniProtKB=Q9NNW7 Q9NNW7 TXNRD2 PTHR48105:SF21 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN REDUCTASE 2, MITOCHONDRIAL biological regulation#GO:0065007;regulation of biological process#GO:0050789;homeostatic process#GO:0042592;cellular process#GO:0009987;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=5200|UniProtKB=Q9Y661 Q9Y661 HS3ST4 PTHR10605:SF11 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 HUMAN|HGNC=15703|UniProtKB=Q9HBH0 Q9HBH0 RHOF PTHR24072:SF99 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOF GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 small GTPase#PC00208 HUMAN|HGNC=17359|UniProtKB=Q7Z3B4 Q7Z3B4 NUP54 PTHR13000:SF0 NUCLEOPORIN P54 NUCLEOPORIN P54 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;protein-containing complex subunit organization#GO:0043933;protein localization to membrane#GO:0072657;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear pore central transport channel#GO:0044613;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=24055|UniProtKB=Q8NFQ8 Q8NFQ8 TOR1AIP2 PTHR18843:SF2 TORSIN-1A-INTERACTING PROTEIN TORSIN-1A-INTERACTING PROTEIN 2 HUMAN|HGNC=25462|UniProtKB=Q9BZ67 Q9BZ67 FRMD8 PTHR13283:SF13 KREV INTERACTION TRAPPED 1-RELATED FERM DOMAIN-CONTAINING PROTEIN 8 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9278|UniProtKB=O15355 O15355 PPM1G PTHR13832:SF805 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1G hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=34437|UniProtKB=Q5BLP8 Q5BLP8 C4orf48 PTHR35451:SF1 NEUROPEPTIDE-LIKE PROTEIN C4ORF48 NEUROPEPTIDE-LIKE PROTEIN C4ORF48 HUMAN|HGNC=7559|UniProtKB=P04198 P04198 MYCN PTHR45851:SF2 MYC PROTO-ONCOGENE N-MYC PROTO-ONCOGENE PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 HUMAN|HGNC=19409|UniProtKB=O43300 O43300 LRRTM2 PTHR45712:SF19 AGAP008170-PA LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=16098|UniProtKB=Q9BVI0 Q9BVI0 PHF20 PTHR15856:SF27 PHD FINGER PROTEIN 20-RELATED PHD FINGER PROTEIN 20 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;histone acetylation#GO:0016573;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;peptidyl-lysine modification#GO:0018205;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=2662|UniProtKB=P98082 P98082 DAB2 PTHR11232:SF30 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER DISABLED HOMOLOG 2 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;membrane organization#GO:0061024;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of endocytosis#GO:0030100;negative regulation of response to stimulus#GO:0048585;endocytosis#GO:0006897;negative regulation of signaling#GO:0023057;positive regulation of transport#GO:0051050;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;negative regulation of signal transduction#GO:0009968;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=2037|UniProtKB=Q9Y5I7 Q9Y5I7 CLDN16 PTHR12002:SF56 CLAUDIN CLAUDIN-16 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=8863|UniProtKB=O15067 O15067 PFAS PTHR10099:SF1 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ligase activity#GO:0016874;catalytic activity#GO:0003824 De novo purine biosynthesis#P02738>Phosphoribosylformylglycinamide synthase#P02898 HUMAN|HGNC=25395|UniProtKB=Q6ZN66 Q6ZN66 GBP6 PTHR10751:SF117 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 6 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830 heterotrimeric G-protein#PC00117 HUMAN|HGNC=10857|UniProtKB=Q8IUQ4 Q8IUQ4 SIAH1 PTHR45877:SF2 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SIAH1 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 p53 pathway feedback loops 2#P04398>SIAH-1#G04711;p53 pathway#P00059>Siah#G04696;Wnt signaling pathway#P00057>SIAH-1#P01433;p53 pathway feedback loops 2#P04398>SIAH-1#P04660 HUMAN|HGNC=6621|UniProtKB=Q05469 Q05469 LIPE PTHR23025:SF3 TRIACYLGLYCEROL LIPASE HORMONE-SENSITIVE LIPASE lipase#PC00143 Triacylglycerol metabolism#P02782>Triacylglycerol lipase#P03205 HUMAN|HGNC=13963|UniProtKB=Q9UGF7 Q9UGF7 OR12D3 PTHR26451:SF819 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 12D3 HUMAN|HGNC=30706|UniProtKB=Q96JA4 Q96JA4 MS4A14 PTHR23320:SF10 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 14 transporter#PC00227 HUMAN|Ensembl=ENSG00000241149|UniProtKB=A0A1W2PQL4 A0A1W2PQL4 ZNF722P PTHR24384:SF228 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 722, PSEUDOGENE-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=10486|UniProtKB=P23297 P23297 S100A1 PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A1-RELATED calmodulin-related#PC00061 HUMAN|HGNC=4137|UniProtKB=Q9H2C0 Q9H2C0 GAN PTHR24412:SF232 KELCH PROTEIN GIGAXONIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=8762|UniProtKB=Q16342 Q16342 PDCD2 PTHR12298:SF4 PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED PROGRAMMED CELL DEATH PROTEIN 2 HUMAN|HGNC=3249|UniProtKB=P41567 P41567 EIF1 PTHR10388:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR 1 nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;ribonucleoprotein complex binding#GO:0043021;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 translation initiation factor#PC00224 HUMAN|HGNC=7876|UniProtKB=P29474 P29474 NOS3 PTHR19384:SF66 NITRIC OXIDE SYNTHASE-RELATED NITRIC OXIDE SYNTHASE, ENDOTHELIAL nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;organic cyclic compound binding#GO:0097159;binding#GO:0005488;catalytic activity#GO:0003824;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;cyclic nucleotide metabolic process#GO:0009187;system process#GO:0003008;positive regulation of cellular metabolic process#GO:0031325;purine nucleotide biosynthetic process#GO:0006164;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;nucleoside phosphate metabolic process#GO:0006753;alpha-amino acid metabolic process#GO:1901605;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;response to molecule of bacterial origin#GO:0002237;carboxylic acid catabolic process#GO:0046395;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;purine nucleotide metabolic process#GO:0006163;oxoacid metabolic process#GO:0043436;regulation of lyase activity#GO:0051339;response to oxygen-containing compound#GO:1901700;interspecies interaction between organisms#GO:0044419;organonitrogen compound biosynthetic process#GO:1901566;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;organic acid metabolic process#GO:0006082;ribose phosphate biosynthetic process#GO:0046390;circulatory system process#GO:0003013;response to lipopolysaccharide#GO:0032496;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;organic acid catabolic process#GO:0016054;ribonucleotide biosynthetic process#GO:0009260;small molecule catabolic process#GO:0044282;positive regulation of phosphate metabolic process#GO:0045937;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;cellular amino acid metabolic process#GO:0006520;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;regulation of metabolic process#GO:0019222;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;blood circulation#GO:0008015;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;arginine catabolic process#GO:0006527;regulation of phosphate metabolic process#GO:0019220;second-messenger-mediated signaling#GO:0019932;organophosphate biosynthetic process#GO:0090407;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;response to lipid#GO:0033993;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;response to bacterium#GO:0009617;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;signaling#GO:0023052;metabolic process#GO:0008152;negative regulation of blood pressure#GO:0045776;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular amino acid catabolic process#GO:0009063;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;carboxylic acid metabolic process#GO:0019752;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 oxidoreductase#PC00176 VEGF signaling pathway#P00056>eNOS#P01422;PI3 kinase pathway#P00048>NOS#P01205;Endothelin signaling pathway#P00019>eNOS#P00578;Interleukin signaling pathway#P00036>eNOS#P00986;Angiogenesis#P00005>eNOS#P00210 HUMAN|HGNC=14579|UniProtKB=Q9NRW7 Q9NRW7 VPS45 PTHR11679:SF3 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=15335|UniProtKB=Q8NGE2 Q8NGE2 OR2AP1 PTHR26454:SF16 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2AP1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=15869|UniProtKB=Q96L93 Q96L93 KIF16B PTHR24115:SF400 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF16B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;ATP-dependent microtubule motor activity, plus-end-directed#GO:0008574;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=4566|UniProtKB=P62993 P62993 GRB2 PTHR46037:SF4 PROTEIN ENHANCER OF SEVENLESS 2B GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 Dopamine receptor mediated signaling pathway#P05912>Grb2#P05949;Ras Pathway#P04393>Grb2#P04544;FGF signaling pathway#P00021>Grb2#P00631;PI3 kinase pathway#P00048>Grb2#P01178;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Grb#P00848;Nicotine pharmacodynamics pathway#P06587>Grb2#P06596;B cell activation#P00010>Grb2#P00372;PDGF signaling pathway#P00047>Grb2#P01148;Angiogenesis#P00005>Grb2#P00234;CCKR signaling map#P06959>GRB2#P07237;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Grb2#P00892;Gonadotropin-releasing hormone receptor pathway#P06664>Grb2#P06856;Interleukin signaling pathway#P00036>Grb2#P00971;Angiogenesis#P00005>Grb2#P00252;EGF receptor signaling pathway#P00018>Grb2#P00550;Integrin signalling pathway#P00034>Grb2#P00910;T cell activation#P00053>Grb2#P01303 HUMAN|HGNC=9491|UniProtKB=Q16651 Q16651 PRSS8 PTHR24253:SF0 TRANSMEMBRANE PROTEASE SERINE PROSTASIN serine protease#PC00203 HUMAN|HGNC=7711|UniProtKB=O43181 O43181 NDUFS4 PTHR12219:SF8 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL oxidoreductase#PC00176 HUMAN|HGNC=8161|UniProtKB=Q9H208 Q9H208 OR10A2 PTHR26453:SF625 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A2 transmembrane signal receptor#PC00197 HUMAN|HGNC=30720|UniProtKB=Q8NA61 Q8NA61 CBY2 PTHR21533:SF13 LEUCINE-RICH PROTEIN PROTEIN CHIBBY HOMOLOG 2 HUMAN|HGNC=14942|UniProtKB=Q86XI6 Q86XI6 PPP1R3B PTHR12307:SF13 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3B phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase 1 binding#GO:0008157;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 monosaccharide metabolic process#GO:0005996;glucan metabolic process#GO:0044042;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;energy derivation by oxidation of organic compounds#GO:0015980;regulation of biological process#GO:0050789;cellular glucan metabolic process#GO:0006073;glucan biosynthetic process#GO:0009250;regulation of biosynthetic process#GO:0009889;oxidation-reduction process#GO:0055114;regulation of macromolecule biosynthetic process#GO:0010556;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;glycogen biosynthetic process#GO:0005978;regulation of glucose metabolic process#GO:0010906;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;polysaccharide metabolic process#GO:0005976;regulation of cellular biosynthetic process#GO:0031326;cellular carbohydrate metabolic process#GO:0044262;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;hexose metabolic process#GO:0019318;energy reserve metabolic process#GO:0006112;cellular polysaccharide biosynthetic process#GO:0033692;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular polysaccharide metabolic process#GO:0044264;small molecule metabolic process#GO:0044281 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 phosphatase modulator#PC00184 HUMAN|HGNC=4284|UniProtKB=P29033 P29033 GJB2 PTHR11984:SF46 CONNEXIN GAP JUNCTION BETA-2 PROTEIN gap junction#PC00105 HUMAN|HGNC=4392|UniProtKB=Q5JWF2 Q5JWF2 GNAS PTHR10218:SF320 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(S) SUBUNIT ALPHA ISOFORMS XLAS pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 regulation of adenylate cyclase activity#GO:0045761;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;dopamine receptor signaling pathway#GO:0007212;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;trans-synaptic signaling#GO:0099537;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;nervous system process#GO:0050877;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117 5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Endothelin signaling pathway#P00019>Gs#P00584;Enkephalin release#P05913>G-Protein (s)#P05977;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Gonadotropin-releasing hormone receptor pathway#P06664>gnas#P06717;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gsalpha#P00705 HUMAN|HGNC=13286|UniProtKB=Q6PIW4 Q6PIW4 FIGNL1 PTHR23074:SF75 AAA DOMAIN-CONTAINING FIDGETIN-LIKE PROTEIN 1 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;ATPase activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=29086|UniProtKB=Q66GS9 Q66GS9 CEP135 PTHR23159:SF18 CENTROSOMAL PROTEIN 2 CENTROSOMAL PROTEIN OF 135 KDA chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=28036|UniProtKB=Q8IXR5 Q8IXR5 FAM178B PTHR16046:SF11 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR 2 PROTEIN FAM178B HUMAN|HGNC=13731|UniProtKB=Q7L5Y9 Q7L5Y9 MAEA PTHR12170:SF2 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25663|UniProtKB=Q9HAJ7 Q9HAJ7 SAP30L PTHR13286:SF5 SAP30 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30L molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=20759|UniProtKB=Q9H1K0 Q9H1K0 RBSN PTHR13510:SF44 FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED RABENOSYN-5 HUMAN|HGNC=12919|UniProtKB=P52742 P52742 ZNF135 PTHR24377:SF925 IP01015P-RELATED ZINC FINGER PROTEIN 135 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=30275|UniProtKB=Q86VW2 Q86VW2 ARHGEF25 PTHR22826:SF117 RHO GUANINE EXCHANGE FACTOR-RELATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 25 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=10818|UniProtKB=P51688 P51688 SGSH PTHR43108:SF6 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-SULPHOGLUCOSAMINE SULPHOHYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;heparan sulfate proteoglycan metabolic process#GO:0030201;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 hydrolase#PC00121 HUMAN|HGNC=6929|UniProtKB=Q01726 Q01726 MC1R PTHR22750:SF2 G-PROTEIN COUPLED RECEPTOR MELANOCYTE-STIMULATING HORMONE RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=4410|UniProtKB=O60262 O60262 GNG7 PTHR13809:SF8 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-7 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Wnt signaling pathway#P00057>Ggamma#P01465;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 HUMAN|HGNC=8925|UniProtKB=P46020 P46020 PHKA1 PTHR10749:SF4 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA, SKELETAL MUSCLE ISOFORM cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 HUMAN|HGNC=11344|UniProtKB=Q9Y5Y6 Q9Y5Y6 ST14 PTHR24253:SF50 TRANSMEMBRANE PROTEASE SERINE SUPPRESSOR OF TUMORIGENICITY 14 PROTEIN serine protease#PC00203 HUMAN|HGNC=17288|UniProtKB=Q6Q788 Q6Q788 APOA5 PTHR18976:SF13 APOLIPOPROTEIN APOLIPOPROTEIN A-V transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;sterol binding#GO:0032934;enzyme activator activity#GO:0008047;phospholipid binding#GO:0005543;enzyme regulator activity#GO:0030234;O-acyltransferase activity#GO:0008374;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;molecular function regulator#GO:0098772;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;cholesterol binding#GO:0015485 sterol metabolic process#GO:0016125;organic hydroxy compound transport#GO:0015850;cellular component biogenesis#GO:0044085;triglyceride homeostasis#GO:0070328;sterol transport#GO:0015918;alcohol biosynthetic process#GO:0046165;cholesterol biosynthetic process#GO:0006695;positive regulation of cellular metabolic process#GO:0031325;cholesterol metabolic process#GO:0008203;lipid biosynthetic process#GO:0008610;lipid transport#GO:0006869;regulation of biological process#GO:0050789;steroid metabolic process#GO:0008202;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;anion transport#GO:0006820;secondary alcohol biosynthetic process#GO:1902653;secondary alcohol metabolic process#GO:1902652;regulation of lipid biosynthetic process#GO:0046890;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;cellular component assembly#GO:0022607;organophosphate ester transport#GO:0015748;organic anion transport#GO:0015711;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;alcohol metabolic process#GO:0006066;phospholipid transport#GO:0015914;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;cholesterol transport#GO:0030301;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;lipoprotein metabolic process#GO:0042157;regulation of lipid metabolic process#GO:0019216;small molecule biosynthetic process#GO:0044283;steroid biosynthetic process#GO:0006694;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;lipid metabolic process#GO:0006629;macromolecule localization#GO:0033036;transport#GO:0006810;protein-containing complex assembly#GO:0065003;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;lipid modification#GO:0030258;positive regulation of biosynthetic process#GO:0009891;organic substance transport#GO:0071702;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;lipid localization#GO:0010876;protein metabolic process#GO:0019538;metabolic process#GO:0008152;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;cellular lipid metabolic process#GO:0044255;sterol biosynthetic process#GO:0016126 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;high-density lipoprotein particle#GO:0034364;extracellular region#GO:0005576 apolipoprotein#PC00052 HUMAN|HGNC=52410|UniProtKB=A0A087WX78 A0A087WX78 ELOA3C PTHR15141:SF74 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN-A3-RELATED HUMAN|HGNC=24126|UniProtKB=Q96SQ7 Q96SQ7 ATOH8 PTHR19290:SF102 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED PROTEIN ATONAL HOMOLOG 8 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=7646|UniProtKB=P11245 P11245 NAT2 PTHR11786:SF6 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 HUMAN|HGNC=5140|UniProtKB=P28356 P28356 HOXD9 PTHR45970:SF4 AGAP004664-PA HOMEOBOX PROTEIN HOX-D9 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18909|UniProtKB=Q9BYQ5 Q9BYQ5 KRTAP4-6 PTHR23262:SF223 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-6-RELATED HUMAN|HGNC=20374|UniProtKB=Q9H4S2 Q9H4S2 GSX1 PTHR24339:SF29 HOMEOBOX PROTEIN EMX-RELATED GS HOMEOBOX 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;generation of neurons#GO:0048699;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=10487|UniProtKB=P60903 P60903 S100A10 PTHR11639:SF74 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A10 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=4687|UniProtKB=Q02153 Q02153 GUCY1B1 PTHR45655:SF2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 guanylate cyclase#PC00114 Gonadotropin-releasing hormone receptor pathway#P06664>GC#P06726;Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 HUMAN|HGNC=34448|UniProtKB=A6NFE2 A6NFE2 SMCO2 PTHR22422:SF5 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5B-RELATED SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=14964|UniProtKB=Q969N4 Q969N4 TAAR8 PTHR24249:SF374 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 8 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=16956|UniProtKB=Q96B01 Q96B01 RAD51AP1 PTHR15361:SF4 RAD51/NUKS-INTERACTING PROTEIN RAD51-ASSOCIATED PROTEIN 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=34434|UniProtKB=Q6R6M4 Q6R6M4 USP17L2 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=14097|UniProtKB=Q96LW9 Q96LW9 ZSCAN31 PTHR23226:SF132 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 31 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=16841|UniProtKB=Q99732 Q99732 LITAF PTHR23292:SF2 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR scaffold/adaptor protein#PC00226 HUMAN|HGNC=18634|UniProtKB=Q6UXZ4 Q6UXZ4 UNC5D PTHR12582:SF5 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5D transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 HUMAN|HGNC=8987|UniProtKB=Q9P1W9 Q9P1W9 PIM2 PTHR22984:SF10 SERINE/THREONINE-PROTEIN KINASE PIM SERINE/THREONINE-PROTEIN KINASE PIM-2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;protein autophosphorylation#GO:0046777;cell death#GO:0008219;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=20296|UniProtKB=Q9Y2H6 Q9Y2H6 FNDC3A PTHR24099:SF9 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 3A ubiquitin-protein ligase#PC00234 HUMAN|HGNC=12918|UniProtKB=P52741 P52741 ZNF134 PTHR24399:SF4 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER PROTEIN 134 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1930|UniProtKB=P05060 P05060 CHGB PTHR10583:SF4 CHROMOGRANIN SECRETOGRANIN-1 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=20454|UniProtKB=Q9H9Y6 Q9H9Y6 POLR1B PTHR20856:SF5 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736 DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 HUMAN|HGNC=6826|UniProtKB=O00754 O00754 MAN2B1 PTHR11607:SF3 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 HUMAN|Ensembl=ENSG00000261968|UniProtKB=A0A0G2JLE6 A0A0G2JLE6 KRTAP4-8 PTHR23262:SF67 KERATIN ASSOCIATED PROTEIN HCG2042992-RELATED HUMAN|HGNC=34397|UniProtKB=P0C870 P0C870 JMJD7 PTHR12461:SF2 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 HUMAN|HGNC=14417|UniProtKB=Q96BH3 Q96BH3 ELSPBP1 PTHR22918:SF2 SEMINAL PLASMA PROTEIN EPIDIDYMAL SPERM-BINDING PROTEIN 1 heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|HGNC=6721|UniProtKB=P29376 P29376 LTK PTHR24416:SF294 TYROSINE-PROTEIN KINASE RECEPTOR LEUKOCYTE TYROSINE KINASE RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;neurogenesis#GO:0022008;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell population proliferation#GO:0008283;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=10006|UniProtKB=Q02094 Q02094 RHAG PTHR11730:SF32 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE A monovalent inorganic cation transmembrane transporter activity#GO:0015077;inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=1357|UniProtKB=Q9NR00 Q9NR00 TCIM PTHR32358:SF1 TRANSCRIPTIONAL AND IMMUNE RESPONSE REGULATOR TRANSCRIPTIONAL AND IMMUNE RESPONSE REGULATOR protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of Notch signaling pathway#GO:0045746;regulation of Notch signaling pathway#GO:0008593;cell activation involved in immune response#GO:0002263;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;negative regulation of cell communication#GO:0010648;Notch signaling pathway#GO:0007219 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18713|UniProtKB=Q86VQ1 Q86VQ1 GLCCI1 PTHR14972:SF3 AGAP011572-PA GLUCOCORTICOID-INDUCED TRANSCRIPT 1 PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9646|UniProtKB=Q12923 Q12923 PTPN13 PTHR46900:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 protein phosphatase#PC00195 HUMAN|HGNC=3011|UniProtKB=Q07507 Q07507 DPT PTHR15040:SF2 DERMATOPONTIN-RELATED DERMATOPONTIN cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;supramolecular fiber organization#GO:0097435;collagen fibril organization#GO:0030199 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cell adhesion molecule#PC00069 HUMAN|HGNC=21584|UniProtKB=Q5M9Q1 Q5M9Q1 NKAPL PTHR13087:SF3 NF-KAPPA B ACTIVATING PROTEIN NKAP-LIKE PROTEIN regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=6821|UniProtKB=P33908 P33908 MAN1A1 PTHR11742:SF31 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IA hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=20977|UniProtKB=Q96RI9 Q96RI9 TAAR9 PTHR24249:SF79 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 9 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=23014|UniProtKB=Q8NBI2 Q8NBI2 CYB561A3 PTHR10106:SF38 CYTOCHROME B561-RELATED CYTOCHROME B ASCORBATE-DEPENDENT PROTEIN 3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 reductase#PC00198 HUMAN|HGNC=16106|UniProtKB=Q96MY1 Q96MY1 NOL4L PTHR12449:SF19 DEATH DOMAIN-CONTAINING PROTEIN NUCLEOLAR PROTEIN 4-LIKE HUMAN|HGNC=6239|UniProtKB=Q9UK17 Q9UK17 KCND3 PTHR11537:SF182 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;establishment of localization#GO:0051234;potassium ion transmembrane transport#GO:0071805;export from cell#GO:0140352;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;cell body#GO:0044297;integral component of plasma membrane#GO:0005887;transmembrane transporter complex#GO:1902495;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=10915|UniProtKB=Q9Y666 Q9Y666 SLC12A7 PTHR11827:SF47 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 7 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;chemical synaptic transmission#GO:0007268;ion homeostasis#GO:0050801;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;signaling#GO:0023052;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cell communication#GO:0007154;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;regulation of cellular component size#GO:0032535;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065 secondary carrier transporter#PC00258 HUMAN|HGNC=18885|UniProtKB=P59535 P59535 TAS2R40 PTHR11394:SF59 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 40 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=17211|UniProtKB=Q92620 Q92620 DHX38 PTHR18934:SF91 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA helicase#PC00032 HUMAN|HGNC=26951|UniProtKB=Q86YL5 Q86YL5 TDRP PTHR35663:SF1 TESTIS DEVELOPMENT-RELATED PROTEIN-RELATED TESTIS DEVELOPMENT-RELATED PROTEIN developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;multi-organism process#GO:0051704;multicellular organismal reproductive process#GO:0048609 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=1962|UniProtKB=P17787 P17787 CHRNB2 PTHR18945:SF865 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095;Nicotine pharmacodynamics pathway#P06587>CHRNB2#P06613;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=18762|UniProtKB=Q495M3 Q495M3 SLC36A2 PTHR22950:SF185 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 2 solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;L-amino acid transmembrane transporter activity#GO:0015179;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;proton transmembrane transporter activity#GO:0015078;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;proton transmembrane transport#GO:1902600;organic acid transport#GO:0015849;alanine transport#GO:0032328;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 amino acid transporter#PC00046 HUMAN|HGNC=9897|UniProtKB=P57052 P57052 RBM11 PTHR13798:SF5 RNA BINDING MOTIF RBM PROTEIN -RELATED SPLICING REGULATOR RBM11 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=7201|UniProtKB=Q9BXT6 Q9BXT6 MOV10L1 PTHR10887:SF419 DNA2/NAM7 HELICASE FAMILY RNA HELICASE MOV10L1 posttranscriptional regulation of gene expression#GO:0010608;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;negative regulation of metabolic process#GO:0009892;gene silencing by RNA#GO:0031047;cellular process#GO:0009987;post-transcriptional gene silencing by RNA#GO:0035194;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;posttranscriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;gene silencing#GO:0016458;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;regulation of gene expression, epigenetic#GO:0040029;metabolic process#GO:0008152 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=16960|UniProtKB=P52954 P52954 LBX1 PTHR24336:SF9 TRANSCRIPTION FACTOR LBX TRANSCRIPTION FACTOR LBX1 homeodomain transcription factor#PC00119 HUMAN|HGNC=16203|UniProtKB=Q96DR5 Q96DR5 BPIFA2 PTHR47145:SF1 BPI FOLD-CONTAINING FAMILY A MEMBER 2 BPI FOLD-CONTAINING FAMILY A MEMBER 2 HUMAN|HGNC=19086|UniProtKB=Q96DB2 Q96DB2 HDAC11 PTHR48252:SF29 HISTONE DEACETYLASE 2-RELATED HISTONE DEACETYLASE 11 HUMAN|HGNC=574|UniProtKB=O00189 O00189 AP4M1 PTHR10529:SF270 AP COMPLEX SUBUNIT MU AP-4 COMPLEX SUBUNIT MU-1 cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;cellular protein localization#GO:0034613;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;lysosomal transport#GO:0007041;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=25223|UniProtKB=Q96H96 Q96H96 COQ2 PTHR11048:SF28 PRENYLTRANSFERASES 4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 acyltransferase#PC00042 Heme biosynthesis#P02746>Protoheme IX farnesyl transferase#P02982 HUMAN|HGNC=2474|UniProtKB=P09228 P09228 CST2 PTHR46186:SF3 CYSTATIN CYSTATIN-S-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=21604|UniProtKB=Q9Y6I3 Q9Y6I3 EPN1 PTHR12276:SF48 EPSIN/ENT-RELATED EPSIN-1 protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 HUMAN|HGNC=14189|UniProtKB=O00453 O00453 LST1 PTHR15452:SF5 LEUKOCYTE-SPECIFIC TRANSCRIPT 1 PROTEIN LEUKOCYTE-SPECIFIC TRANSCRIPT 1 PROTEIN cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;dendrite development#GO:0016358;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=8847|UniProtKB=P56645 P56645 PER3 PTHR11269:SF13 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;response to radiation#GO:0009314;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;response to light stimulus#GO:0009416;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>Per#P00504;Circadian clock system#P00015>per#G01499 HUMAN|HGNC=1133|UniProtKB=Q06187 Q06187 BTK PTHR24418:SF92 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BTK B cell activation#P00010>Btk#P00400 HUMAN|HGNC=8966|UniProtKB=Q9Y2B2 Q9Y2B2 PIGL PTHR12993:SF11 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 deacetylase#PC00087 HUMAN|HGNC=33843|UniProtKB=Q7Z6K4 Q7Z6K4 NRARP PTHR24203:SF38 ANKYRIN REPEAT FAMILY PROTEIN NOTCH-REGULATED ANKYRIN REPEAT-CONTAINING PROTEIN HUMAN|HGNC=6145|UniProtKB=Q13797 Q13797 ITGA9 PTHR23220:SF69 INTEGRIN ALPHA INTEGRIN ALPHA-9 integrin#PC00126 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853;Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=5114|UniProtKB=P14651 P14651 HOXB3 PTHR45664:SF11 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-B3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=23416|UniProtKB=Q641Q2 Q641Q2 WASHC2A PTHR21669:SF1 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS WASH COMPLEX SUBUNIT 2A-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=30086|UniProtKB=Q6P1R4 Q6P1R4 DUS1L PTHR11082:SF5 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(16/17) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 RNA processing factor#PC00147 HUMAN|HGNC=1459|UniProtKB=Q14012 Q14012 CAMK1 PTHR24347:SF197 SERINE/THREONINE-PROTEIN KINASE CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=1185|UniProtKB=Q9NQ88 Q9NQ88 TIGAR PTHR46517:SF1 FRUCTOSE-2,6-BISPHOSPHATASE TIGAR FRUCTOSE-2,6-BISPHOSPHATASE TIGAR hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;purine nucleoside diphosphate metabolic process#GO:0009135;regulation of response to DNA damage stimulus#GO:2001020;regulation of catabolic process#GO:0009894;secondary metabolic process#GO:0019748;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;regulation of cellular amide metabolic process#GO:0034248;positive regulation of biological process#GO:0048518;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;oxoacid metabolic process#GO:0043436;macromolecule metabolic process#GO:0043170;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;negative regulation of nitrogen compound metabolic process#GO:0051172;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;negative regulation of cell death#GO:0060548;response to stress#GO:0006950;cellular carbohydrate metabolic process#GO:0044262;regulation of cellular process#GO:0050794;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;nucleotide metabolic process#GO:0009117;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;small molecule metabolic process#GO:0044281;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of DNA repair#GO:0045739;negative regulation of cellular metabolic process#GO:0031324;carbohydrate derivative metabolic process#GO:1901135;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of DNA repair#GO:0006282;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;negative regulation of programmed cell death#GO:0043069;cellular carbohydrate catabolic process#GO:0044275;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cell death#GO:0008219;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;cellular catabolic process#GO:0044248;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;ADP metabolic process#GO:0046031;negative regulation of phosphorus metabolic process#GO:0010563;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of cell death#GO:0010941;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;cellular amide metabolic process#GO:0043603;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phosphatase#PC00181 Cobalamin biosynthesis#P02735>Ribazole-5-phosphate phosphatase#P02881 HUMAN|HGNC=33522|UniProtKB=A6NGC4 A6NGC4 TLCD2 PTHR13439:SF2 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 2 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;endomembrane system organization#GO:0010256;homeostatic process#GO:0042592;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;chemical homeostasis#GO:0048878;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=9364|UniProtKB=Q92954 Q92954 PRG4 PTHR22917:SF1 HEMOPEXIN DOMAIN-CONTAINING PROTEIN PROTEOGLYCAN 4 HUMAN|HGNC=6139|UniProtKB=P26006 P26006 ITGA3 PTHR23220:SF89 INTEGRIN ALPHA INTEGRIN ALPHA-3 integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=9920|UniProtKB=P50120 P50120 RBP2 PTHR11955:SF59 FATTY ACID BINDING PROTEIN RETINOL-BINDING PROTEIN 2 HUMAN|HGNC=14980|UniProtKB=P57768 P57768 SNX16 PTHR22999:SF37 PX SERINE/THREONINE KINASE PXK SORTING NEXIN-16 HUMAN|HGNC=12840|UniProtKB=P54577 P54577 YARS1 PTHR11586:SF43 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER TYROSINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 translational protein#PC00263 HUMAN|HGNC=19231|UniProtKB=Q9NTU4 Q9NTU4 CATSPERZ PTHR42155:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT ZETA CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT ZETA male gamete generation#GO:0048232;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;microtubule-based movement#GO:0007018;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;cilium movement involved in cell motility#GO:0060294;cell differentiation#GO:0030154;spermatogenesis#GO:0007283;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;sperm capacitation#GO:0048240;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;multi-organism process#GO:0051704;cilium movement#GO:0003341;localization#GO:0051179;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;cilium-dependent cell motility#GO:0060285;reproduction#GO:0000003;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;intracellular organelle#GO:0043229;voltage-gated calcium channel complex#GO:0005891;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intrinsic component of membrane#GO:0031224;CatSper complex#GO:0036128;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;transmembrane transporter complex#GO:1902495;B axonemal microtubule#GO:0097650;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;membrane protein complex#GO:0098796;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;ion channel complex#GO:0034702;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;cation channel complex#GO:0034703;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;sperm principal piece#GO:0097228;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=14404|UniProtKB=Q8TBG4 Q8TBG4 ETNPPL PTHR45688:SF1 FAMILY NOT NAMED ETHANOLAMINE-PHOSPHATE PHOSPHO-LYASE cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3146|UniProtKB=P42892 P42892 ECE1 PTHR11733:SF130 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED ENDOTHELIN-CONVERTING ENZYME 1 metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 HUMAN|HGNC=17282|UniProtKB=Q86UR5 Q86UR5 RIMS1 PTHR12157:SF18 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 1 Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;ion channel binding#GO:0044325;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rab GTPase binding#GO:0017137 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>RIM1alpha/2alpha#P05776 HUMAN|HGNC=17153|UniProtKB=Q9BVN2 Q9BVN2 RUSC1 PTHR15591:SF11 RUN AND SH3 DOMAIN CONTAINING RUN AND SH3 DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=30490|UniProtKB=Q7Z309 Q7Z309 FAM122B PTHR22227:SF1 UNCHARACTERIZED PROTEIN FAM122B HUMAN|HGNC=16136|UniProtKB=Q9H4G8 Q9H4G8 DPH3P1 PTHR21454:SF23 DPH3 HOMOLOG-RELATED DPH3 HOMOLOG B-RELATED cellular aromatic compound metabolic process#GO:0006725;posttranscriptional regulation of gene expression#GO:0010608;tRNA metabolic process#GO:0006399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;translation#GO:0006412;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;tRNA wobble uridine modification#GO:0002098;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5211|UniProtKB=P37059 P37059 HSD17B2 PTHR43313:SF3 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C ESTRADIOL 17-BETA-DEHYDROGENASE 2 dehydrogenase#PC00092 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 HUMAN|HGNC=8023|UniProtKB=P20783 P20783 NTF3 PTHR11589:SF4 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIN-3 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;protein binding#GO:0005515;molecular function regulator#GO:0098772;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 neuron apoptotic process#GO:0051402;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;system process#GO:0003008;positive regulation of cellular metabolic process#GO:0031325;neuron death#GO:0070997;positive regulation of protein modification process#GO:0031401;negative regulation of neuron death#GO:1901215;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cognition#GO:0050890;apoptotic process#GO:0006915;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;positive regulation of macromolecule metabolic process#GO:0010604;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;negative regulation of cell death#GO:0060548;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of neuron death#GO:1901214;response to growth factor#GO:0070848;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;behavior#GO:0007610;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;cellular response to chemical stimulus#GO:0070887;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;nervous system process#GO:0050877;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;peptidyl-serine modification#GO:0018209;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270 neurotrophic factor#PC00163 HUMAN|HGNC=14358|UniProtKB=P78414 P78414 IRX1 PTHR11211:SF13 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=28611|UniProtKB=Q6R327 Q6R327 RICTOR PTHR13298:SF11 CYTOSOLIC REGULATOR PIANISSIMO RAPAMYCIN-INSENSITIVE COMPANION OF MTOR regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;TOR signaling#GO:0031929 TORC2 complex#GO:0031932;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=13745|UniProtKB=Q9BTV5 Q9BTV5 FSD1 PTHR24099:SF4 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 1 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=3797|UniProtKB=P53539 P53539 FOSB PTHR23351:SF3 FOS TRANSCRIPTION FACTOR-RELATED PROTEIN FOSB cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 PDGF signaling pathway#P00047>c-fos#P01145;Gonadotropin-releasing hormone receptor pathway#P06664>Fosb#G06878;Angiogenesis#P00005>c-Fos#P00235;Gonadotropin-releasing hormone receptor pathway#P06664>FOS#P06709;Apoptosis signaling pathway#P00006>Fos#P00317;Huntington disease#P00029>Fos protein#P00801;Gonadotropin-releasing hormone receptor pathway#P06664>Fosb#G06666;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>c-fos#P00884 HUMAN|HGNC=20397|UniProtKB=Q5U623 Q5U623 ATF7IP2 PTHR23210:SF23 ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 2 transcription cofactor#PC00217 HUMAN|HGNC=18854|UniProtKB=Q8TEY5 Q8TEY5 CREB3L4 PTHR45996:SF2 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 HUMAN|HGNC=28752|UniProtKB=Q86UD1 Q86UD1 OAF PTHR13423:SF2 OUT AT FIRST OUT AT FIRST PROTEIN HOMOLOG HUMAN|HGNC=24488|UniProtKB=Q8NBT0 Q8NBT0 POC1A PTHR44019:SF2 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG A HUMAN|HGNC=25623|UniProtKB=Q53HC5 Q53HC5 KLHL26 PTHR45632:SF13 LD33804P KELCH-LIKE PROTEIN 26 HUMAN|HGNC=1781|UniProtKB=Q00532 Q00532 CDKL1 PTHR24056:SF192 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 1 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=8599|UniProtKB=Q96RD7 Q96RD7 PANX1 PTHR15759:SF5 PANNEXIN PANNEXIN-1 HUMAN|HGNC=30379|UniProtKB=Q96EE3 Q96EE3 SEH1L PTHR11024:SF3 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER NUCLEOPORIN SEH1 cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;TOR signaling#GO:0031929;regulation of cell communication#GO:0010646;TORC1 signaling#GO:0038202;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;localization#GO:0051179;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;protein-containing complex localization#GO:0031503 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=21114|UniProtKB=Q6UWU4 Q6UWU4 C6orf89 PTHR35259:SF1 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 HUMAN|HGNC=20380|UniProtKB=Q8NEX5 Q8NEX5 WFDC9 PTHR19441:SF16 WHEY ACDIC PROTEIN WAP PROTEIN WFDC9 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antibacterial humoral response#GO:0019731;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=32043|UniProtKB=Q6UWJ8 Q6UWJ8 CD164L2 PTHR11337:SF11 MUCIN/PORIMIN CD164 SIALOMUCIN-LIKE 2 PROTEIN cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=24118|UniProtKB=Q8IXQ6 Q8IXQ6 PARP9 PTHR14453:SF70 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP9 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme binding#GO:0019899 negative regulation of gene expression#GO:0010629;response to external biotic stimulus#GO:0043207;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;gene expression#GO:0010467;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;positive regulation of signaling#GO:0023056;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;cellular response to cytokine stimulus#GO:0071345;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cell communication#GO:0010647;regulation of defense response#GO:0031347;biological regulation#GO:0065007;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=8973|UniProtKB=O75747 O75747 PIK3C2G PTHR10048:SF29 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT GAMMA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;phosphatidylinositol-mediated signaling#GO:0048015;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;phosphatidylinositol 3-kinase signaling#GO:0014065;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;inositol lipid-mediated signaling#GO:0048017;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477;locomotion#GO:0040011;phosphatidylinositol phosphorylation#GO:0046854 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Endothelin signaling pathway#P00019>PI3K#P00577;Integrin signalling pathway#P00034>PI3K#P00936 HUMAN|HGNC=4576|UniProtKB=O43424 O43424 GRID2 PTHR18966:SF109 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 amino acid binding#GO:0016597;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;anion binding#GO:0043168;ion binding#GO:0043167;glutamate binding#GO:0016595;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=20458|UniProtKB=Q8WXF5 Q8WXF5 CRYGN PTHR11818:SF22 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN N structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=1062|UniProtKB=P53004 P53004 BLVRA PTHR43377:SF1 BILIVERDIN REDUCTASE A BILIVERDIN REDUCTASE A dehydrogenase#PC00092 HUMAN|HGNC=3433|UniProtKB=P07992 P07992 ERCC1 PTHR12749:SF0 EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1 DNA EXCISION REPAIR PROTEIN ERCC-1 damaged DNA binding#GO:0003684;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;mismatch repair#GO:0006298;nucleobase-containing compound metabolic process#GO:0006139;cellular response to abiotic stimulus#GO:0071214;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;response to radiation#GO:0009314;mitotic recombination#GO:0006312;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to light stimulus#GO:0071482;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleotide-excision repair, DNA incision#GO:0033683;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organelle organization#GO:0006996;response to UV#GO:0009411;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;organelle fission#GO:0048285;cellular response to stress#GO:0033554;cellular response to environmental stimulus#GO:0104004;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;nucleotide-excision repair complex#GO:0000109;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 endodeoxyribonuclease#PC00093 HUMAN|HGNC=1158|UniProtKB=P30536 P30536 TSPO PTHR10057:SF5 PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR TRANSLOCATOR PROTEIN lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;cholesterol binding#GO:0015485;sterol binding#GO:0032934 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;outer membrane#GO:0019867;plasma membrane#GO:0005886 HUMAN|HGNC=28976|UniProtKB=Q14679 Q14679 TTLL4 PTHR12241:SF145 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL4 cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=9108|UniProtKB=Q13794 Q13794 PMAIP1 PTHR14299:SF0 PHORBOL-12-MYRISTATE-13-ACETATE-INDUCED PROTEIN 1 PHORBOL-12-MYRISTATE-13-ACETATE-INDUCED PROTEIN 1 p53 pathway#P00059>NOXA#G01572 HUMAN|HGNC=4727|UniProtKB=Q99878 Q99878 H2AC14 PTHR23430:SF345 HISTONE H2A HISTONE H2A TYPE 1-J heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=21257|UniProtKB=Q9Y530 Q9Y530 OARD1 PTHR12521:SF0 PROTEIN C6ORF130 ADP-RIBOSE GLYCOHYDROLASE OARD1 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein modification process#GO:0036211;cellular process#GO:0009987;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238 HUMAN|HGNC=25674|UniProtKB=Q9HAF1 Q9HAF1 MEAF6 PTHR13476:SF0 UNCHARACTERIZED CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 histone H3 acetylation#GO:0043966;peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;histone H4 acetylation#GO:0043967;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=8807|UniProtKB=P29803 P29803 PDHA2 PTHR11516:SF27 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA, TESTIS-SPECIFIC FORM, MITOCHONDRIAL membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;oxidoreductase complex#GO:1990204;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092 TCA cycle#P00051>Pyruvate Dehydrogenase#P01266;Pyruvate metabolism#P02772>Pyruvate Dehydrogenase#P03133 HUMAN|HGNC=2362|UniProtKB=P46108 P46108 CRK PTHR19969:SF8 SH2-SH3 ADAPTOR PROTEIN-RELATED ADAPTER MOLECULE CRK scaffold/adaptor protein#PC00226 Integrin signalling pathway#P00034>Crk#P00933;CCKR signaling map#P06959>CRK#P07125;Angiogenesis#P00005>Crk#P00207 HUMAN|HGNC=15207|UniProtKB=Q96RD2 Q96RD2 OR52B2 PTHR26450:SF151 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52B2 transmembrane signal receptor#PC00197 HUMAN|HGNC=2721|UniProtKB=O43150 O43150 ASAP2 PTHR45854:SF4 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 HUMAN|Gene=YD019_HUMAN|UniProtKB=Q6ZRP5 Q6ZRP5 - PTHR45134:SF15 FAMILY NOT NAMED C2H2-TYPE DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=9398|UniProtKB=Q13516 Q13516 OLIG2 PTHR19290:SF32 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED OLIGODENDROCYTE TRANSCRIPTION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=15761|UniProtKB=Q9H1P3 Q9H1P3 OSBPL2 PTHR10972:SF153 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;cholesterol binding#GO:0015485 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26707|UniProtKB=Q6A162 Q6A162 KRT40 PTHR23239:SF90 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 40 HUMAN|HGNC=25590|UniProtKB=Q9ULD0 Q9ULD0 OGDHL PTHR23152:SF5 2-OXOGLUTARATE DEHYDROGENASE 2-OXOGLUTARATE DEHYDROGENASE-LIKE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;oxidoreductase complex#GO:1990204;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 HUMAN|HGNC=6857|UniProtKB=Q99683 Q99683 MAP3K5 PTHR11584:SF332 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 non-receptor serine/threonine protein kinase#PC00167 Integrin signalling pathway#P00034>ERK#P00907;FAS signaling pathway#P00020>ASK1#P00614;p38 MAPK pathway#P05918>ASK1#P06043;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;FGF signaling pathway#P00021>MEKK1-5#P00634;EGF receptor signaling pathway#P00018>MEKK1-5#P00553;Apoptosis signaling pathway#P00006>ASK1#P00272 HUMAN|HGNC=13395|UniProtKB=O96009 O96009 NAPSA PTHR47966:SF56 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED NAPSIN-A cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16944|UniProtKB=Q96I25 Q96I25 RBM17 PTHR13288:SF8 SPLICING FACTOR 45 SPF45 SPLICING FACTOR 45 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;cellular response to stress#GO:0033554;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=15041|UniProtKB=Q6IFH4 Q6IFH4 OR6B2 PTHR26452:SF222 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6B2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=21332|UniProtKB=Q86UX6 Q86UX6 STK32C PTHR24356:SF153 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE 32C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=11359|UniProtKB=P49675 P49675 STAR PTHR46489:SF1 STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL HUMAN|HGNC=6797|UniProtKB=P43363 P43363 MAGEA10 PTHR11736:SF153 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 10 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26570|UniProtKB=B1ANS9 B1ANS9 WDR64 PTHR44324:SF2 WD40 REPEAT DOMAIN 95 WD REPEAT-CONTAINING PROTEIN 64 HUMAN|HGNC=17581|UniProtKB=Q96GX9 Q96GX9 APIP PTHR10640:SF7 METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydratase#PC00091 HUMAN|HGNC=473|UniProtKB=P48728 P48728 AMT PTHR43757:SF2 AMINOMETHYLTRANSFERASE AMINOMETHYLTRANSFERASE, MITOCHONDRIAL methyltransferase#PC00155 HUMAN|HGNC=21492|UniProtKB=Q8N0U8 Q8N0U8 VKORC1L1 PTHR14519:SF5 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1-LIKE PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176 HUMAN|HGNC=10806|UniProtKB=Q16585 Q16585 SGCB PTHR21142:SF2 SARCOGLYCANS BETA-SARCOGLYCAN non-motor actin binding protein#PC00165 HUMAN|HGNC=19687|UniProtKB=Q9P2K8 Q9P2K8 EIF2AK4 PTHR11042:SF136 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EIF-2-ALPHA KINASE GCN2 translation regulator activity#GO:0045182;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=12733|UniProtKB=Q9Y6W5 Q9Y6W5 WASF2 PTHR12902:SF6 WASP-1 WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER 2 protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cell leading edge#GO:0031252;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 HUMAN|HGNC=5127|UniProtKB=Q00444 Q00444 HOXC5 PTHR45659:SF5 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-C5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=7408|UniProtKB=P25713 P25713 MT3 PTHR23299:SF18 METALLOTHIONEIN METALLOTHIONEIN-3 cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;divalent inorganic cation homeostasis#GO:0072507;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;transition metal ion homeostasis#GO:0055076;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cation homeostasis#GO:0055080;positive regulation of macromolecule metabolic process#GO:0010604;cellular ion homeostasis#GO:0006873;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;response to toxic substance#GO:0009636;positive regulation of ERK1 and ERK2 cascade#GO:0070374;metal ion homeostasis#GO:0055065;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;cellular homeostasis#GO:0019725;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular transition metal ion homeostasis#GO:0046916;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;ERK1 and ERK2 cascade#GO:0070371;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;response to metal ion#GO:0010038;homeostatic process#GO:0042592;protein phosphorylation#GO:0006468;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;regulation of primary metabolic process#GO:0080090;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=19580|UniProtKB=Q9H2C5 Q9H2C5 OR52A5 PTHR26450:SF48 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52A5 transmembrane signal receptor#PC00197 HUMAN|HGNC=34242|UniProtKB=A8MTA8 A8MTA8 FAM166B PTHR22146:SF8 CAT EYE SYNDROME CRITICAL REGION PROTEIN 6 PROTEIN FAM166B HUMAN|HGNC=18275|UniProtKB=Q969K4 Q969K4 ABTB1 PTHR46231:SF1 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=18140|UniProtKB=Q9UBD6 Q9UBD6 RHCG PTHR11730:SF30 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER RH TYPE C monovalent inorganic cation transmembrane transporter activity#GO:0015077;inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=19189|UniProtKB=Q96HP0 Q96HP0 DOCK6 PTHR23317:SF65 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 6 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=5785|UniProtKB=P06310 P06310 IGKV2-30 PTHR23267:SF475 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-30-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=6450|UniProtKB=O76009 O76009 KRT33A PTHR23239:SF98 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA3-I HUMAN|HGNC=21727|UniProtKB=Q67FW5 Q67FW5 B3GNTL1 PTHR22916:SF3 GLYCOSYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN 1 glycosyltransferase#PC00111 HUMAN|HGNC=15522|UniProtKB=Q9NS61 Q9NS61 KCNIP2 PTHR23055:SF65 CALCIUM BINDING PROTEINS KV CHANNEL-INTERACTING PROTEIN 2 HUMAN|HGNC=26245|UniProtKB=A8MT70 A8MT70 ZBBX PTHR28634:SF1 ZINC FINGER B-BOX DOMAIN-CONTAINING PROTEIN 1 ZINC FINGER B-BOX DOMAIN-CONTAINING PROTEIN 1 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017;cilium movement#GO:0003341 motile cilium#GO:0031514;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=25151|UniProtKB=Q96EY9 Q96EY9 ADAT3 PTHR11079:SF156 CYTOSINE DEAMINASE FAMILY MEMBER INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 deaminase#PC00088 HUMAN|HGNC=2367|UniProtKB=P02741 P02741 CRP PTHR45869:SF7 C-REACTIVE PROTEIN-RELATED C-REACTIVE PROTEIN complement binding#GO:0001848;low-density lipoprotein particle binding#GO:0030169;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488 response to external biotic stimulus#GO:0043207;negative regulation of biological process#GO:0048519;activation of immune response#GO:0002253;humoral immune response#GO:0006959;lymphocyte mediated immunity#GO:0002449;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;adaptive immune response#GO:0002250;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;defense response#GO:0006952;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;leukocyte mediated immunity#GO:0002443;regulation of immune response#GO:0050776;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;biological regulation#GO:0065007;complement activation#GO:0006956 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=19172|UniProtKB=Q8IZ96 Q8IZ96 CMTM1 PTHR22776:SF43 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=29940|UniProtKB=Q9UHL3 Q9UHL3 FAM153A PTHR40712:SF2 FAMILY WITH SEQUENCE SIMILARITY 153 MEMBER C-RELATED PROTEIN FAM153A-RELATED HUMAN|HGNC=4480|UniProtKB=O00155 O00155 GPR25 PTHR24228:SF9 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTOR 25-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=20085|UniProtKB=Q8NHQ9 Q8NHQ9 DDX55 PTHR24031:SF2 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX55 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17871|UniProtKB=Q9NPI5 Q9NPI5 NMRK2 PTHR10285:SF143 URIDINE KINASE NICOTINAMIDE RIBOSIDE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 nucleotide kinase#PC00172 HUMAN|HGNC=21490|UniProtKB=A0PJW8 A0PJW8 DAPL1 PTHR13177:SF2 DEATH-ASSOCIATED PROTEIN 1 DEATH-ASSOCIATED PROTEIN-LIKE 1 protein binding#GO:0005515;binding#GO:0005488 negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;response to extracellular stimulus#GO:0009991;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;cellular response to starvation#GO:0009267;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;response to nutrient levels#GO:0031667;negative regulation of autophagy#GO:0010507;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;negative regulation of catabolic process#GO:0009895;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=25016|UniProtKB=Q9NP77 Q9NP77 SSU72 PTHR20383:SF11 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;mRNA 3'-end processing#GO:0031124;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;mRNA polyadenylation#GO:0006378;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;dephosphorylation#GO:0016311;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 protein phosphatase#PC00195 HUMAN|HGNC=30958|UniProtKB=Q969S3 Q969S3 ZNF622 PTHR13182:SF8 ZINC FINGER PROTEIN 622 ZINC FINGER PROTEIN 622 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987;ribonucleoprotein complex biogenesis#GO:0022613 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991;preribosome, large subunit precursor#GO:0030687 RNA metabolism protein#PC00031 HUMAN|HGNC=1612|UniProtKB=O00421 O00421 CCRL2 PTHR10489:SF655 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR-LIKE 2 response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response#GO:0006952;immune response#GO:0006955;inflammatory response#GO:0006954 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=20074|UniProtKB=Q504Q3 Q504Q3 PAN2 PTHR15728:SF0 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 exoribonuclease#PC00099 HUMAN|HGNC=10293|UniProtKB=Q96AT9 Q96AT9 RPE PTHR11749:SF3 RIBULOSE-5-PHOSPHATE-3-EPIMERASE RIBULOSE-PHOSPHATE 3-EPIMERASE-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;isomerase activity#GO:0016853;ion binding#GO:0043167;binding#GO:0005488;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;glucose 6-phosphate metabolic process#GO:0051156;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;oxidation-reduction process#GO:0055114;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852 HUMAN|HGNC=33857|UniProtKB=Q5FWF7 Q5FWF7 FBXO48 PTHR12874:SF24 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 48 HUMAN|HGNC=24772|UniProtKB=Q8IX94 Q8IX94 CTAGE4 PTHR23158:SF57 MELANOMA INHIBITORY ACTIVITY-RELATED CTAGE FAMILY MEMBER 15-RELATED endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=27339|UniProtKB=Q8NCU8 Q8NCU8 MTLN PTHR37154:SF1 MITOREGULIN MITOREGULIN cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of membrane potential#GO:0042391;regulation of sequestering of calcium ion#GO:0051282;regulation of localization#GO:0032879;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;sequestering of calcium ion#GO:0051208;cellular ion homeostasis#GO:0006873;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;cellular chemical homeostasis#GO:0055082;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of cellular process#GO:0050794;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065;positive regulation of biological process#GO:0048518 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=3614|UniProtKB=Q92637 Q92637 FCGR1B PTHR11481:SF11 IMMUNOGLOBULIN FC RECEPTOR HIGH AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR I-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;immune system process#GO:0002376;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of immune response#GO:0050776;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=21698|UniProtKB=Q9NWF9 Q9NWF9 RNF216 PTHR22770:SF44 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF216 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin binding#GO:0043130;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=7175|UniProtKB=P22894 P22894 MMP8 PTHR10201:SF137 MATRIX METALLOPROTEINASE NEUTROPHIL COLLAGENASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Plasminogen activating cascade#P00050>MMP-13#P01250;Plasminogen activating cascade#P00050>pro-MMP-13#P01254;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=33108|UniProtKB=Q6NX45 Q6NX45 ZNF774 PTHR24377:SF924 IP01015P-RELATED ZINC FINGER PROTEIN 774 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10667|UniProtKB=Q96C92 Q96C92 ENTR1 PTHR31259:SF6 ENDOSOME-ASSOCIATED TRAFFICKING REGULATOR 1 ENDOSOME-ASSOCIATED-TRAFFICKING REGULATOR 1 microtubule-based protein transport#GO:0099118;endosomal transport#GO:0016197;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;axoneme assembly#GO:0035082;regulation of cell division#GO:0051302;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of cytokinesis#GO:0032465;regulation of protein localization#GO:0032880;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;regulation of cellular localization#GO:0060341;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;cell division#GO:0051301;macromolecule localization#GO:0033036;positive regulation of cell projection organization#GO:0031346;positive regulation of organelle organization#GO:0010638;cellular protein localization#GO:0034613;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;positive regulation of cellular component biogenesis#GO:0044089;cytokinesis#GO:0000910;vesicle-mediated transport to the plasma membrane#GO:0098876;membrane fission#GO:0090148;vesicle localization#GO:0051648;intraciliary transport involved in cilium assembly#GO:0035735;retrograde transport, endosome to plasma membrane#GO:1990126;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cell projection assembly#GO:0060491;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;centrosome#GO:0005813;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;recycling endosome#GO:0055037;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;membrane protein complex#GO:0098796;microtubule organizing center#GO:0005815;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cell periphery#GO:0071944;centriole#GO:0005814;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=15283|UniProtKB=Q8NGK9 Q8NGK9 OR5D16 PTHR48018:SF3 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D16 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=12289|UniProtKB=A0A0C4DH28 A0A0C4DH28 TRGV4 PTHR19256:SF57 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 2-RELATED HUMAN|HGNC=24273|UniProtKB=Q96FB5 Q96FB5 RRNAD1 PTHR12496:SF2 CGI-41 METHYLTRANSFERASE PROTEIN RRNAD1 RNA methyltransferase#PC00033 HUMAN|HGNC=17078|UniProtKB=O75122 O75122 CLASP2 PTHR21567:SF30 CLASP CLIP-ASSOCIATING PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;mitotic spindle assembly#GO:0090307;regulation of microtubule cytoskeleton organization#GO:0070507;spindle assembly#GO:0051225;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;organelle fission#GO:0048285;cell cycle#GO:0007049 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;spindle microtubule#GO:0005876;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=8956|UniProtKB=Q15735 Q15735 INPP5J PTHR11200:SF127 INOSITOL 5-PHOSPHATASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 5-PHOSPHATASE A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;alcohol metabolic process#GO:0006066;glycerophospholipid metabolic process#GO:0006650;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;cellular protein modification process#GO:0006464;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;organophosphate metabolic process#GO:0019637;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;phospholipid dephosphorylation#GO:0046839;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;phosphatidylinositol metabolic process#GO:0046488;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;peptidyl-serine modification#GO:0018209;cellular lipid metabolic process#GO:0044255 cell leading edge#GO:0031252;cytoplasm#GO:0005737;intracellular#GO:0005622;ruffle#GO:0001726;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=19093|UniProtKB=Q9NYI0 Q9NYI0 PSD3 PTHR10663:SF337 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 3 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=1504|UniProtKB=P42574 P42574 CASP3 PTHR10454:SF198 CASPASE CASPASE-3 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 neurogenesis#GO:0022008;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;nervous system development#GO:0007399;skin development#GO:0043588;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;epidermis development#GO:0008544;positive regulation of programmed cell death#GO:0043068;regulation of biological quality#GO:0065008;apoptotic process#GO:0006915;cell death#GO:0008219;neuron differentiation#GO:0030182;hemopoiesis#GO:0030097;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;epidermal cell differentiation#GO:0009913;regulation of apoptotic process#GO:0042981;immune system development#GO:0002520;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;programmed cell death#GO:0012501;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;erythrocyte differentiation#GO:0030218;positive regulation of cellular process#GO:0048522;immune system process#GO:0002376;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of cell death#GO:0010941;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;positive regulation of cell death#GO:0010942 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 FAS signaling pathway#P00020>Pro-Caspase3#P00608;FAS signaling pathway#P00020>Caspase3#P00599;CCKR signaling map#P06959>Pro-caspase-3#P07231;CCKR signaling map#P06959>Caspase-3#P07108;Huntington disease#P00029>Caspase 3#P00812;Apoptosis signaling pathway#P00006>Caspase 3#P00305 HUMAN|HGNC=17895|UniProtKB=Q16763 Q16763 UBE2S PTHR24068:SF393 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 S ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=6985|UniProtKB=Q16798 Q16798 ME3 PTHR23406:SF20 MALIC ENZYME-RELATED NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176 HUMAN|HGNC=12146|UniProtKB=A0A0A6YYK1 A0A0A6YYK1 TRAV8-1 PTHR19367:SF31 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-1 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=6415|UniProtKB=P13646 P13646 KRT13 PTHR23239:SF121 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 13 HUMAN|HGNC=24717|UniProtKB=Q96EY7 Q96EY7 PTCD3 PTHR16276:SF1 PENTATRICOPEPTIDE REPEAT DOMAIN-CONTAINING PROTEIN 3 PENTATRICOPEPTIDE REPEAT DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;rRNA binding#GO:0019843 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=2737|UniProtKB=Q92771 Q92771 DDX12P PTHR11472:SF41 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER ATP-DEPENDENT DNA HELICASE DDX11-RELATED pyrophosphatase activity#GO:0016462;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;DNA conformation change#GO:0071103;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA duplex unwinding#GO:0032508;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059;DNA geometric change#GO:0032392 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA helicase#PC00011 HUMAN|HGNC=10569|UniProtKB=P29508 P29508 SERPINB3 PTHR11461:SF320 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B3 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=13800|UniProtKB=Q9GZZ6 Q9GZZ6 CHRNA10 PTHR18945:SF889 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-10 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=7451|UniProtKB=Q13615 Q13615 MTMR3 PTHR10807:SF66 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;regulation of cellular catabolic process#GO:0031329;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=12394|UniProtKB=O95801 O95801 TTC4 PTHR46035:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 4 TETRATRICOPEPTIDE REPEAT PROTEIN 4 HUMAN|HGNC=8557|UniProtKB=Q13310 Q13310 PABPC4 PTHR24012:SF365 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=33706|UniProtKB=A6NMZ2 A6NMZ2 SNTN PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A1-RELATED calmodulin-related#PC00061 HUMAN|HGNC=7930|UniProtKB=Q86SE8 Q86SE8 NPM2 PTHR22747:SF14 NUCLEOPLASMIN NUCLEOPLASMIN-2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;histone binding#GO:0042393 cellular aromatic compound metabolic process#GO:0006725;positive regulation of DNA replication#GO:0045740;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;chromatin remodeling#GO:0006338;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chaperone#PC00072 HUMAN|HGNC=10860|UniProtKB=P15907 P15907 ST6GAL1 PTHR46059:SF2 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 1 transferase#PC00220 HUMAN|HGNC=18504|UniProtKB=Q7L513 Q7L513 FCRLA PTHR11481:SF71 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=41|UniProtKB=Q9NRK6 Q9NRK6 ABCB10 PTHR24221:SF609 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=25519|UniProtKB=Q9NW15 Q9NW15 ANO10 PTHR12308:SF40 NGEP-RELATED ANOCTAMIN-10 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=4579|UniProtKB=P39086 P39086 GRIK1 PTHR18966:SF36 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 1 amino acid binding#GO:0016597;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;molecular transducer activity#GO:0060089;ion binding#GO:0043167;anion binding#GO:0043168;sodium channel activity#GO:0005272;glutamate binding#GO:0016595;signaling receptor activity#GO:0038023;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;monovalent inorganic cation transmembrane transporter activity#GO:0015077;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;transporter activity#GO:0005215;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA#P01026;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>KA1#P01004;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group I pathway#P00041>GluR5#P01054 HUMAN|HGNC=14999|UniProtKB=Q8NGZ3 Q8NGZ3 OR13G1 PTHR26451:SF237 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 13G1 HUMAN|HGNC=29149|UniProtKB=Q6ZVD8 Q6ZVD8 PHLPP2 PTHR45752:SF10 LEUCINE-RICH REPEAT-CONTAINING PH DOMAIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN PHOSPHATASE 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 scaffold/adaptor protein#PC00226 HUMAN|HGNC=33784|UniProtKB=Q6ZNB7 Q6ZNB7 AGMO PTHR21624:SF1 STEROL DESATURASE-RELATED PROTEIN ALKYLGLYCEROL MONOOXYGENASE HUMAN|HGNC=28592|UniProtKB=Q4G1C9 Q4G1C9 GLIPR1L2 PTHR10334:SF236 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIPR1-LIKE PROTEIN 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=5248|UniProtKB=Q12988 Q12988 HSPB3 PTHR47097:SF1 HEAT SHOCK PROTEIN BETA-3 HEAT SHOCK PROTEIN BETA-3 cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear speck#GO:0016607;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=21013|UniProtKB=Q6UX71 Q6UX71 PLXDC2 PTHR13055:SF11 TUMOR ENDOTHELIAL MARKER 7 RELATED PLEXIN DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=5756|UniProtKB=P04432 P04432 IGKV1D-39 PTHR23267:SF394 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-39-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=11027|UniProtKB=P02730 P02730 SLC4A1 PTHR11453:SF12 ANION EXCHANGE PROTEIN BAND 3 ANION TRANSPORT PROTEIN secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;anion:anion antiporter activity#GO:0015301;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=29551|UniProtKB=Q3YBR2 Q3YBR2 TBRG1 PTHR22715:SF0 TRANSFORMING GROWTH FACTOR BETA REGULATED GENE 1 TRANSFORMING GROWTH FACTOR BETA REGULATOR 1 growth factor#PC00112 HUMAN|HGNC=13430|UniProtKB=Q9Y577 Q9Y577 TRIM17 PTHR24103:SF397 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM17 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9191|UniProtKB=O15514 O15514 POLR2D PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 single-stranded RNA binding#GO:0003727;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098;translation initiation factor binding#GO:0031369;RNA binding#GO:0003723;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;heterocycle catabolic process#GO:0046700;ribonucleoprotein complex subunit organization#GO:0071826;positive regulation of translational initiation#GO:0045948;gene expression#GO:0010467;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ribonucleoprotein complex assembly#GO:0022618;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of translation#GO:0045727;protein-containing complex subunit organization#GO:0043933;macromolecule catabolic process#GO:0009057;cellular protein-containing complex assembly#GO:0034622;establishment of RNA localization#GO:0051236;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;cellular nitrogen compound catabolic process#GO:0044270;mRNA 3'-end processing#GO:0031124;amide transport#GO:0042886;positive regulation of biosynthetic process#GO:0009891;organic substance transport#GO:0071702;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;cellular response to heat#GO:0034605;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;protein export from nucleus#GO:0006611;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to heat#GO:0009408;organonitrogen compound metabolic process#GO:1901564;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;amide biosynthetic process#GO:0043604;DNA-templated transcription, initiation#GO:0006352;positive regulation of protein metabolic process#GO:0051247;aromatic compound catabolic process#GO:0019439;nucleocytoplasmic transport#GO:0006913;mRNA processing#GO:0006397;intracellular protein transport#GO:0006886;response to temperature stimulus#GO:0009266;cellular macromolecule catabolic process#GO:0044265;RNA export from nucleus#GO:0006405;transcription by RNA polymerase II#GO:0006366;negative regulation of gene expression#GO:0010629;cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nitrogen compound transport#GO:0071705;regulation of translational initiation#GO:0006446;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;response to abiotic stimulus#GO:0009628;positive regulation of biological process#GO:0048518;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;RNA biosynthetic process#GO:0032774;peptide transport#GO:0015833;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;peptide biosynthetic process#GO:0043043;response to stress#GO:0006950;nuclear export#GO:0051168;protein transport#GO:0015031;aromatic compound biosynthetic process#GO:0019438;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;protein-containing complex localization#GO:0031503;positive regulation of nitrogen compound metabolic process#GO:0051173;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule localization#GO:0033036;peptide metabolic process#GO:0006518;transport#GO:0006810;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;nucleic acid transport#GO:0050657;ribonucleoprotein complex export from nucleus#GO:0071426;translation#GO:0006412;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;cellular macromolecule biosynthetic process#GO:0034645;RNA 3'-end processing#GO:0031123;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;mRNA transport#GO:0051028;ribonucleoprotein complex localization#GO:0071166;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound transport#GO:0015931;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;establishment of localization in cell#GO:0051649;translational initiation#GO:0006413;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 supramolecular complex#GO:0099080;membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 HUMAN|HGNC=25798|UniProtKB=Q0P6D6 Q0P6D6 CCDC15 PTHR14817:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 15 COILED-COIL DOMAIN-CONTAINING PROTEIN 15 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=13567|UniProtKB=Q9NYA3 Q9NYA3 GOLGA6A PTHR10881:SF44 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 6A-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=2483|UniProtKB=Q05048 Q05048 CSTF1 PTHR44133:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;mRNA cleavage factor complex#GO:0005849;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=8533|UniProtKB=P51575 P51575 P2RX1 PTHR10125:SF9 P2X PURINOCEPTOR P2X PURINOCEPTOR 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|Ensembl=ENSG00000278178|UniProtKB=A0A0G2JNH3 A0A0G2JNH3 ENSG00000278178 PTHR48002:SF4 OLFACTORY RECEPTOR OLFACTORY RECEPTOR-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=11199|UniProtKB=P41225 P41225 SOX3 PTHR10270:SF111 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=24188|UniProtKB=Q9BRK5 Q9BRK5 SDF4 PTHR10827:SF51 RETICULOCALBIN 45 KDA CALCIUM-BINDING PROTEIN calmodulin-related#PC00061 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 HUMAN|HGNC=8002|UniProtKB=P54845 P54845 NRL PTHR10129:SF24 TRANSCRIPTION FACTOR MAF NEURAL RETINA-SPECIFIC LEUCINE ZIPPER PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;sensory system development#GO:0048880;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;neuron development#GO:0048666;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;retina development in camera-type eye#GO:0060041;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;visual system development#GO:0150063;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;camera-type eye development#GO:0043010;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=570|UniProtKB=P53677 P53677 AP3M2 PTHR10529:SF341 AP COMPLEX SUBUNIT MU AP-3 COMPLEX SUBUNIT MU-2 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 HUMAN|HGNC=1470|UniProtKB=Q96RR4 Q96RR4 CAMKK2 PTHR43895:SF39 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2 HUMAN|HGNC=2690|UniProtKB=P07108 P07108 DBI PTHR23310:SF54 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN transfer/carrier protein#PC00219 HUMAN|HGNC=14682|UniProtKB=Q5VX52 Q5VX52 SPATA1 PTHR14421:SF3 SPERMATOGENESIS-ASSOCIATED PROTEIN 1 SPERMATOGENESIS-ASSOCIATED PROTEIN 1 HUMAN|HGNC=22208|UniProtKB=Q8IVD9 Q8IVD9 NUDCD3 PTHR12356:SF19 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 3 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=18989|UniProtKB=Q8IZF5 Q8IZF5 ADGRF3 PTHR45813:SF2 FAMILY NOT NAMED ADHESION G-PROTEIN COUPLED RECEPTOR F3 HUMAN|HGNC=17752|UniProtKB=O60637 O60637 TSPAN3 PTHR19282:SF48 TETRASPANIN TETRASPANIN-3 response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=15178|UniProtKB=Q8NGE8 Q8NGE8 OR4D9 PTHR48002:SF108 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D9 transmembrane signal receptor#PC00197 HUMAN|HGNC=29858|UniProtKB=Q9UBE8 Q9UBE8 NLK PTHR24055:SF380 MITOGEN-ACTIVATED PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE NLK MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Nemo-like Kinase#P01449 HUMAN|HGNC=14347|UniProtKB=Q9H6U6 Q9H6U6 BCAS3 PTHR13268:SF0 BREAST CARCINOMA AMPLIFIED SEQUENCE 3 BREAST CARCINOMA-AMPLIFIED SEQUENCE 3 response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to nutrient levels#GO:0031667;response to stress#GO:0006950;response to extracellular stimulus#GO:0009991;response to starvation#GO:0042594 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=4760|UniProtKB=Q16778 Q16778 H2BC21 PTHR23428:SF322 HISTONE H2B HISTONE H2B TYPE 2-E nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=7190|UniProtKB=Q9NZB8 Q9NZB8 MOCS1 PTHR22960:SF26 MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1 HUMAN|HGNC=20886|UniProtKB=Q9NUQ2 Q9NUQ2 AGPAT5 PTHR10983:SF16 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE EPSILON acyltransferase#PC00042 HUMAN|HGNC=15578|UniProtKB=Q96D71 Q96D71 REPS1 PTHR11216:SF63 EH DOMAIN RALBP1-ASSOCIATED EPS DOMAIN-CONTAINING PROTEIN 1 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=22198|UniProtKB=O75127 O75127 PTCD1 PTHR24014:SF6 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL RNA metabolism protein#PC00031 HUMAN|HGNC=13700|UniProtKB=Q8N6P7 Q8N6P7 IL22RA1 PTHR20859:SF20 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=4707|UniProtKB=P54840 P54840 GYS2 PTHR10176:SF1 GLYCOGEN SYNTHASE GLYCOGEN [STARCH] SYNTHASE, LIVER transferase activity, transferring hexosyl groups#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity, transferring glycosyl groups#GO:0016757;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glucan metabolic process#GO:0044042;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;glycogen metabolic process#GO:0005977;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;glycogen biosynthetic process#GO:0005978;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;cellular glucan metabolic process#GO:0006073;polysaccharide metabolic process#GO:0005976;glucan biosynthetic process#GO:0009250;cellular carbohydrate metabolic process#GO:0044262;oxidation-reduction process#GO:0055114;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;cellular polysaccharide biosynthetic process#GO:0033692;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Glycogen synthase D#P00709 HUMAN|HGNC=6216|UniProtKB=O75449 O75449 KATNA1 PTHR23074:SF71 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A1 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;ATPase activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=16948|UniProtKB=Q969H8 Q969H8 MYDGF PTHR31230:SF1 MYELOID-DERIVED GROWTH FACTOR MYDGF MYELOID-DERIVED GROWTH FACTOR extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=5035|UniProtKB=P07910 P07910 HNRNPC PTHR13968:SF3 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS C1/C2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=6163|UniProtKB=P26012 P26012 ITGB8 PTHR10082:SF9 INTEGRIN BETA SUBUNIT INTEGRIN BETA-8 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;biological adhesion#GO:0022610;localization of cell#GO:0051674;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052 membrane protein complex#GO:0098796;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;focal adhesion#GO:0005925;integral component of plasma membrane#GO:0005887;cell-substrate junction#GO:0030055;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 HUMAN|HGNC=16806|UniProtKB=O95071 O95071 UBR5 PTHR46276:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR5 E3 UBIQUITIN-PROTEIN LIGASE UBR5 DNA repair#GO:0006281;regulation of double-strand break repair#GO:2000779;regulation of protein modification process#GO:0031399;regulation of response to DNA damage stimulus#GO:2001020;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of chromatin organization#GO:1902275;histone ubiquitination#GO:0016574;negative regulation of cellular component organization#GO:0051129;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;histone modification#GO:0016570;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;chromosome organization#GO:0051276;negative regulation of protein ubiquitination#GO:0031397;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of histone modification#GO:0031056;regulation of DNA repair#GO:0006282;organic cyclic compound metabolic process#GO:1901360;negative regulation of organelle organization#GO:0010639;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;histone H2A ubiquitination#GO:0033522;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;protein K63-linked ubiquitination#GO:0070534;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Hedgehog signaling pathway#P00025>Ubiquitin ligase#P00693 HUMAN|HGNC=29471|UniProtKB=Q6UX15 Q6UX15 LAYN PTHR14789:SF2 CHONDROLECTIN VARIANT CHODLFDELTAE. LAYILIN carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168;glycosaminoglycan binding#GO:0005539 HUMAN|HGNC=7542|UniProtKB=Q9BRK3 Q9BRK3 MXRA8 PTHR44793:SF1 MATRIX REMODELING-ASSOCIATED PROTEIN 8 MATRIX REMODELING-ASSOCIATED PROTEIN 8 HUMAN|Ensembl=ENSG00000237378|UniProtKB=A0A3B3IRQ3 A0A3B3IRQ3 LOC112267897 PTHR31294:SF17 FAMILY NOT NAMED KERATIN-ASSOCIATED PROTEIN 21-1 HUMAN|HGNC=9505|UniProtKB=Q9UIA0 Q9UIA0 CYTH4 PTHR10663:SF323 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-4 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=4398|UniProtKB=P62879 P62879 GNB2 PTHR19850:SF27 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(T) SUBUNIT BETA-2 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Wnt signaling pathway#P00057>GBeta#P01457;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;PI3 kinase pathway#P00048>Gbetagamma#P01188;GABA-B receptor II signaling#P05731>Gbeta#P05755;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753 HUMAN|HGNC=1936|UniProtKB=Q13231 Q13231 CHIT1 PTHR11177:SF248 CHITINASE CHITOTRIOSIDASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;carbohydrate derivative binding#GO:0097367;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;binding#GO:0005488;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110 HUMAN|HGNC=15714|UniProtKB=P42704 P42704 LRPPRC PTHR46669:SF1 LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL HUMAN|HGNC=34388|UniProtKB=A8MYP8 A8MYP8 ODF3B PTHR21580:SF19 SHIPPO-1-RELATED OUTER DENSE FIBER PROTEIN 3B intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 structural protein#PC00211 HUMAN|HGNC=5922|UniProtKB=A0A075B6J1 A0A075B6J1 IGLV5-37 PTHR23267:SF325 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 5-37-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=17283|UniProtKB=Q9UQ26 Q9UQ26 RIMS2 PTHR12157:SF15 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2 Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;ion channel binding#GO:0044325;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rab GTPase binding#GO:0017137 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;presynaptic active zone#GO:0048786;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>RIM1alpha/2alpha#P05776 HUMAN|HGNC=1688|UniProtKB=P19256 P19256 CD58 PTHR21063:SF5 LFA-3 LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3 HUMAN|HGNC=9235|UniProtKB=Q03181 Q03181 PPARD PTHR24082:SF15 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;negative regulation of inflammatory response#GO:0050728;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;regulation of defense response#GO:0031347;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of lipid metabolic process#GO:0019216;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;inflammatory response#GO:0006954;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of inflammatory response#GO:0050727;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 HUMAN|HGNC=26715|UniProtKB=Q3B8N5 Q3B8N5 PROX2 PTHR12198:SF5 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 PROSPERO HOMEOBOX PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=30316|UniProtKB=Q96R05 Q96R05 RBP7 PTHR11955:SF97 FATTY ACID BINDING PROTEIN RETINOID-BINDING PROTEIN 7 HUMAN|HGNC=17052|UniProtKB=O94979 O94979 SEC31A PTHR13923:SF23 SEC31-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC31A endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;Golgi vesicle budding#GO:0048194;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;COPII-coated vesicle budding#GO:0090114;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=13390|UniProtKB=Q9GZT8 Q9GZT8 NIF3L1 PTHR13799:SF13 NGG1 INTERACTING FACTOR 3 NIF3-LIKE PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=44445|UniProtKB=D6RBQ6 D6RBQ6 USP17L17 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=11617|UniProtKB=Q15369 Q15369 ELOC PTHR20648:SF11 ELONGIN-C ELONGIN-C transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of transcription elongation from RNA polymerase II promoter#GO:0032968;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;regulation of DNA-templated transcription, elongation#GO:0032784;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleic acid-templated transcription#GO:0097659;regulation of transcription elongation from RNA polymerase II promoter#GO:0034243;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;regulation of nucleobase-containing compound metabolic process#GO:0019219;transcription elongation from RNA polymerase II promoter#GO:0006368;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023 general transcription factor#PC00259 HUMAN|HGNC=1537|UniProtKB=O75081 O75081 CBFA2T3 PTHR10379:SF6 MTG8 ETO EIGHT TWENTY ONE PROTEIN PROTEIN CBFA2T3 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=18302|UniProtKB=Q9NU22 Q9NU22 MDN1 PTHR48103:SF2 MIDASIN-RELATED MIDASIN cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991 HUMAN|HGNC=30839|UniProtKB=Q7Z3Z0 Q7Z3Z0 KRT25 PTHR23239:SF160 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 25 HUMAN|HGNC=17808|UniProtKB=Q9UPT8 Q9UPT8 ZC3H4 PTHR13119:SF23 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 4 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244 HUMAN|HGNC=19277|UniProtKB=Q8TDE3 Q8TDE3 RNASE8 PTHR11437:SF25 RIBONUCLEASE RIBONUCLEASE 8 ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;defense response to fungus#GO:0050832;defense response to Gram-positive bacterium#GO:0050830;defense response to Gram-negative bacterium#GO:0050829;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=4708|UniProtKB=P12544 P12544 GZMA PTHR24271:SF69 KALLIKREIN-RELATED GRANZYME A serine protease#PC00203 HUMAN|HGNC=68|UniProtKB=O14678 O14678 ABCD4 PTHR11384:SF28 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER LYSOSOMAL COBALAMIN TRANSPORTER ABCD4 transporter activity#GO:0005215;lipid transporter activity#GO:0005319 lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;cellular localization#GO:0051641;macromolecule localization#GO:0033036;organic acid transport#GO:0015849;transport#GO:0006810;very long-chain fatty acid metabolic process#GO:0000038;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;lipid transport#GO:0006869;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;anion transport#GO:0006820;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;lipid oxidation#GO:0034440;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ion transmembrane transport#GO:0034220;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;organic acid transmembrane transport#GO:1903825;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;peroxisome organization#GO:0007031;long-chain fatty acid transport#GO:0015909;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;microbody membrane#GO:0031903;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=26483|UniProtKB=Q96MS3 Q96MS3 GLT1D1 PTHR46660:SF2 FAMILY NOT NAMED GLYCOSYLTRANSFERASE 1 DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=7825|UniProtKB=Q9NZG7 Q9NZG7 NINJ2 PTHR12316:SF24 NINJURIN-RELATED NINJURIN-2 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell adhesion molecule#PC00069 HUMAN|HGNC=26783|UniProtKB=Q96GF1 Q96GF1 RNF185 PTHR12313:SF13 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF185 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 cellular response to misfolded protein#GO:0071218;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;ERAD pathway#GO:0036503;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;response to topologically incorrect protein#GO:0035966;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=16073|UniProtKB=Q8TD22 Q8TD22 SFXN5 PTHR11153:SF17 SIDEROFLEXIN SIDEROFLEXIN-5 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;citrate transport#GO:0015746 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068 HUMAN|HGNC=32179|UniProtKB=A6NLW8 A6NLW8 DUXA PTHR46123:SF1 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN A homeodomain transcription factor#PC00119 HUMAN|HGNC=37096|UniProtKB=A6NI47 A6NI47 POTEM PTHR24118:SF94 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER E-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=9876|UniProtKB=O14827 O14827 RASGRF2 PTHR23113:SF187 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 2 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=4923|UniProtKB=P52789 P52789 HK2 PTHR19443:SF4 HEXOKINASE HEXOKINASE-2 transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;cellular homeostasis#GO:0019725;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;chemical homeostasis#GO:0048878;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;cellular chemical homeostasis#GO:0055082;glycolytic process#GO:0006096;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 Pentose phosphate pathway#P02762>Hexokinase#P03079;Glycolysis#P00024>Hexokinase#P00677;Fructose galactose metabolism#P02744>Hexokinase#P02966 HUMAN|HGNC=4689|UniProtKB=Q02846 Q02846 GUCY2D PTHR11920:SF228 GUANYLYL CYCLASE RETINAL GUANYLYL CYCLASE 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;organophosphate biosynthetic process#GO:0090407;cyclic nucleotide metabolic process#GO:0009187;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 guanylate cyclase#PC00114 CCKR signaling map#P06959>Guanylate cyclase#P07116 HUMAN|HGNC=18177|UniProtKB=Q8TF65 Q8TF65 GIPC2 PTHR12259:SF3 RGS-GAIP INTERACTING PROTEIN GIPC PDZ DOMAIN-CONTAINING PROTEIN GIPC2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=160|UniProtKB=O94805 O94805 ACTL6B PTHR11937:SF196 ACTIN ACTIN-LIKE PROTEIN 6B chromatin binding#GO:0003682;binding#GO:0005488 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone H4 acetylation#GO:0043967;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 actin and actin related protein#PC00039 HUMAN|HGNC=28065|UniProtKB=Q2WGJ9 Q2WGJ9 FER1L6 PTHR12546:SF37 FER-1-LIKE FER-1-LIKE PROTEIN 6 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;membrane organization#GO:0061024;plasma membrane organization#GO:0007009 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=43616|UniProtKB=P59074 P59074 CHMP4BP1 PTHR22761:SF41 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4B-LIKE PROTEIN CHMP4BP1-RELATED endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;leaflet of membrane bilayer#GO:0097478;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562 membrane traffic protein#PC00150 HUMAN|HGNC=10923|UniProtKB=P36021 P36021 SLC16A2 PTHR11360:SF123 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 8 secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=18907|UniProtKB=Q9BYQ7 Q9BYQ7 KRTAP4-1 PTHR23262:SF208 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-1 HUMAN|HGNC=12195|UniProtKB=A0A1B0GX68 A0A1B0GX68 TRBV2 PTHR23268:SF45 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=12403|UniProtKB=Q8WZ42 Q8WZ42 TTN PTHR13817:SF70 TITIN TITIN HUMAN|HGNC=6344|UniProtKB=Q9UEF7 Q9UEF7 KL PTHR10353:SF10 GLYCOSYL HYDROLASE KLOTHO glucosidase activity#GO:0015926;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;growth factor receptor binding#GO:0070851;fibroblast growth factor binding#GO:0017134;growth factor binding#GO:0019838;protein binding#GO:0005515;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 response to organic substance#GO:0010033;fibroblast growth factor receptor signaling pathway#GO:0008543;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 glycosidase#PC00110 HUMAN|HGNC=30310|UniProtKB=Q9BSG5 Q9BSG5 RTBDN PTHR10517:SF19 FOLATE RECEPTOR RETBINDIN signaling receptor activity#GO:0038023;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;molecular transducer activity#GO:0060089;ion binding#GO:0043167;anion binding#GO:0043168;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;anchored component of plasma membrane#GO:0046658;intrinsic component of membrane#GO:0031224;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;anchored component of membrane#GO:0031225;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=30301|UniProtKB=Q96JE7 Q96JE7 SEC16B PTHR13402:SF11 RGPR-RELATED PROTEIN TRANSPORT PROTEIN SEC16B vesicle targeting, to, from or within Golgi#GO:0048199;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;Golgi vesicle budding#GO:0048194;transport#GO:0006810;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;regulation of protein transport#GO:0051223;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of protein localization#GO:0032880;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;protein localization to endoplasmic reticulum#GO:0070972;vesicle localization#GO:0051648;Golgi organization#GO:0007030;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;regulation of cellular localization#GO:0060341;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;COPII-coated vesicle budding#GO:0090114;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 bounding membrane of organelle#GO:0098588;ER to Golgi transport vesicle membrane#GO:0012507;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum exit site#GO:0070971;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;Golgi-associated vesicle membrane#GO:0030660;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=4265|UniProtKB=P01286 P01286 GHRH PTHR11213:SF6 GLUCAGON-FAMILY NEUROPEPTIDE SOMATOLIBERIN neuropeptide hormone activity#GO:0005184;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;molecular function regulator#GO:0098772;protein binding#GO:0005515;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 regulation of adenylate cyclase activity#GO:0045761;positive regulation of cell population proliferation#GO:0008284;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;positive regulation of peptide hormone secretion#GO:0090277;hormone secretion#GO:0046879;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of secretion#GO:0051046;secretion#GO:0046903;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;hormone transport#GO:0009914;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of peptide hormone secretion#GO:0090276;positive regulation of growth#GO:0045927;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;regulation of multicellular organismal process#GO:0051239;positive regulation of secretion#GO:0051047;positive regulation of transport#GO:0051050;cell communication#GO:0007154;peptide transport#GO:0015833;positive regulation of hormone secretion#GO:0046887;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of secretion by cell#GO:1903532;cAMP-mediated signaling#GO:0019933;export from cell#GO:0140352;regulation of peptide transport#GO:0090087;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;positive regulation of peptide secretion#GO:0002793;developmental process#GO:0032502;transport#GO:0006810;growth#GO:0040007;regulation of growth#GO:0040008;peptide secretion#GO:0002790;regulation of catalytic activity#GO:0050790;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;peptide hormone secretion#GO:0030072;regulation of hormone secretion#GO:0046883;signal release#GO:0023061;signaling#GO:0023052;cell-cell signaling#GO:0007267;secretion by cell#GO:0032940;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;developmental growth#GO:0048589;regulation of cell population proliferation#GO:0042127;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;localization#GO:0051179;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;cyclic-nucleotide-mediated signaling#GO:0019935 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;extracellular region#GO:0005576;neuronal cell body#GO:0043025;cell junction#GO:0030054;terminal bouton#GO:0043195;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;axon terminus#GO:0043679;cell body#GO:0044297;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;perikaryon#GO:0043204;distal axon#GO:0150034;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 neuropeptide#PC00162 HUMAN|HGNC=25514|UniProtKB=Q3KQU3 Q3KQU3 MAP7D1 PTHR15073:SF2 MICROTUBULE-ASSOCIATED PROTEIN MAP7 DOMAIN-CONTAINING PROTEIN 1 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=17937|UniProtKB=Q86UP6 Q86UP6 CUZD1 PTHR14002:SF27 ENDOGLIN/TGF-BETA RECEPTOR TYPE III CUB AND ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1 cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=40044|UniProtKB=Q8WW34 Q8WW34 TMEM239 PTHR37356:SF1 TRANSMEMBRANE PROTEIN 239 TRANSMEMBRANE PROTEIN 239 HUMAN|HGNC=18810|UniProtKB=Q96P56 Q96P56 CATSPER2 PTHR46923:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2 male gamete generation#GO:0048232;fertilization#GO:0009566;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;microtubule-based movement#GO:0007018;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;cilium movement involved in cell motility#GO:0060294;cell differentiation#GO:0030154;spermatogenesis#GO:0007283;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;sperm capacitation#GO:0048240;cellular developmental process#GO:0048869;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;multi-organism process#GO:0051704;cilium movement#GO:0003341;localization#GO:0051179;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;cilium-dependent cell motility#GO:0060285;reproduction#GO:0000003;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;voltage-gated calcium channel complex#GO:0005891;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;CatSper complex#GO:0036128;transmembrane transporter complex#GO:1902495;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=17175|UniProtKB=Q9P212 Q9P212 PLCE1 PTHR10336:SF6 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE EPSILON-1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 HUMAN|HGNC=14950|UniProtKB=Q96KQ4 Q96KQ4 PPP1R13B PTHR24131:SF5 APOPTOSIS-STIMULATING OF P53 PROTEIN APOPTOSIS-STIMULATING OF P53 PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=30596|UniProtKB=Q86VD9 Q86VD9 PIGZ PTHR22760:SF3 GLYCOSYLTRANSFERASE GPI MANNOSYLTRANSFERASE 4 transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 HUMAN|HGNC=30832|UniProtKB=Q96Q05 Q96Q05 TRAPPC9 PTHR21512:SF5 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=12336|UniProtKB=Q9UBN4 Q9UBN4 TRPC4 PTHR10117:SF25 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 HUMAN|HGNC=8740|UniProtKB=Q9HD42 Q9HD42 CHMP1A PTHR10476:SF17 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1A endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;peptide transport#GO:0015833;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=12822|UniProtKB=Q9NQW7 Q9NQW7 XPNPEP1 PTHR43763:SF6 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 1 protease#PC00190 HUMAN|HGNC=2985|UniProtKB=Q14183 Q14183 DOC2A PTHR45729:SF1 RABPHILIN, ISOFORM A DOUBLE C2-LIKE DOMAIN-CONTAINING PROTEIN ALPHA HUMAN|HGNC=23510|UniProtKB=Q9NX94 Q9NX94 WBP1L PTHR16209:SF4 FAMILY NOT NAMED WW DOMAIN BINDING PROTEIN 1-LIKE HUMAN|HGNC=25973|UniProtKB=Q3T8J9 Q3T8J9 GON4L PTHR16088:SF3 YY1 ASSOCIATED PROTEIN-RELATED GON-4-LIKE PROTEIN-RELATED transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=19090|UniProtKB=Q9HAK2 Q9HAK2 EBF2 PTHR10747:SF33 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=18404|UniProtKB=Q8IZU0 Q8IZU0 FAM9B PTHR19368:SF2 XLR/SCP3/FAM9 PROTEIN FAM9B male gamete generation#GO:0048232;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;spermatid differentiation#GO:0048515;cell differentiation#GO:0030154;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;meiotic cell cycle#GO:0051321;multicellular organism reproduction#GO:0032504;cellular component organization#GO:0016043;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;cell cycle#GO:0007049 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=9980|UniProtKB=O75679 O75679 RFPL3 PTHR25462:SF279 BONUS, ISOFORM C-RELATED RET FINGER PROTEIN-LIKE 3 HUMAN|HGNC=32272|UniProtKB=P0C7X0 P0C7X0 FAM90A24P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=37247|UniProtKB=Q96FH0 Q96FH0 BORCS8 PTHR21146:SF0 MEF2B PROTEIN BLOC-1-RELATED COMPLEX SUBUNIT 8 p38 MAPK pathway#P05918>MEF#P06023 HUMAN|HGNC=10364|UniProtKB=P62424 P62424 RPL7A PTHR23105:SF161 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER 60S RIBOSOMAL PROTEIN L7A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=1528|UniProtKB=P51636 P51636 CAV2 PTHR10844:SF3 CAVEOLIN CAVEOLIN-2 enzyme binding#GO:0019899;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cellular component biogenesis#GO:0044085;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;plasma membrane organization#GO:0007009;positive regulation of cellular metabolic process#GO:0031325;endomembrane system organization#GO:0010256;positive regulation of protein modification process#GO:0031401;cell population proliferation#GO:0008283;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;epithelial cell proliferation#GO:0050673;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular component assembly#GO:0022607;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;endothelial cell proliferation#GO:0001935;protein modification process#GO:0036211;MAPK cascade#GO:0000165;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;negative regulation of cell population proliferation#GO:0008285;cellular response to insulin stimulus#GO:0032869;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;insulin receptor signaling pathway#GO:0008286;regulation of cell population proliferation#GO:0042127;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;response to hormone#GO:0009725;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 plasma membrane raft#GO:0044853;perinuclear region of cytoplasm#GO:0048471;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of plasma membrane#GO:0005887;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;intrinsic component of plasma membrane#GO:0031226;membrane raft#GO:0045121;membrane microdomain#GO:0098857;membrane region#GO:0098589;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=1940|UniProtKB=P24386 P24386 CHM PTHR11787:SF12 RAB GDP-DISSOCIATION INHIBITOR RAB PROTEINS GERANYLGERANYLTRANSFERASE COMPONENT A 1 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;localization#GO:0051179;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein prenylation#GO:0018342;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 G-protein modulator#PC00022 HUMAN|HGNC=14947|UniProtKB=Q9BZL4 Q9BZL4 PPP1R12C PTHR24179:SF27 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12C phosphatase binding#GO:0019902;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphatase regulator activity#GO:0019208;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phosphatase modulator#PC00184 HUMAN|HGNC=40053|UniProtKB=A0A1B0GWK0 A0A1B0GWK0 PVALEF PTHR23064:SF29 TROPONIN PARVALBUMIN-LIKE EF-HAND-CONTAINING PROTEIN cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;actin filament binding#GO:0051015;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ion binding#GO:0043167;actin binding#GO:0003779 regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;regulation of muscle contraction#GO:0006937;skeletal muscle contraction#GO:0003009;system process#GO:0003008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of system process#GO:0044057;striated muscle contraction#GO:0006941;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=22982|UniProtKB=Q92613 Q92613 JADE3 PTHR13793:SF27 PHD FINGER PROTEINS PROTEIN JADE-3 histone H3 acetylation#GO:0043966;peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;histone H4 acetylation#GO:0043967;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 zinc finger transcription factor#PC00244 HUMAN|HGNC=1666|UniProtKB=P11049 P11049 CD37 PTHR19282:SF263 TETRASPANIN LEUKOCYTE ANTIGEN CD37 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=26730|UniProtKB=Q8N9H9 Q8N9H9 C1orf127 PTHR38653:SF1 GENE 572-RELATED GENE 572-RELATED HUMAN|HGNC=20661|UniProtKB=Q70HW3 Q70HW3 SLC25A26 PTHR45667:SF9 S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158 HUMAN|HGNC=25926|UniProtKB=Q5VYS4 Q5VYS4 MEDAG PTHR33769:SF3 TESTIS-EXPRESSED PROTEIN 26 ISOFORM X3 MESENTERIC ESTROGEN-DEPENDENT ADIPOGENESIS PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=3663|UniProtKB=P98174 P98174 FGD1 PTHR12673:SF79 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 1 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=11808|UniProtKB=Q96EY1 Q96EY1 DNAJA3 PTHR44145:SF3 DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL chaperone#PC00072 HUMAN|HGNC=20998|UniProtKB=Q9GZU0 Q9GZU0 C6orf62 PTHR28336:SF1 BA1-643 BA1-643 HUMAN|HGNC=20470|UniProtKB=Q9UK45 Q9UK45 LSM7 PTHR10553:SF5 SMALL NUCLEAR RIBONUCLEOPROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA splicing factor#PC00148 HUMAN|HGNC=18708|UniProtKB=Q9Y3R0 Q9Y3R0 GRIP1 PTHR46227:SF3 GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1 nuclear receptor binding#GO:0016922;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;DNA-binding transcription factor binding#GO:0140297 endosomal transport#GO:0016197;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;protein localization to plasma membrane#GO:0072659;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;retrograde transport, endosome to plasma membrane#GO:1990126;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 HUMAN|HGNC=6059|UniProtKB=P14902 P14902 IDO1 PTHR28657:SF2 INDOLEAMINE 2,3-DIOXYGENASE INDOLEAMINE 2,3-DIOXYGENASE 1 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;organophosphate biosynthetic process#GO:0090407;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;aromatic amino acid family metabolic process#GO:0009072;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;cellular amino acid metabolic process#GO:0006520;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxygenase#PC00177 HUMAN|HGNC=21894|UniProtKB=Q9H875 Q9H875 PRKRIP1 PTHR13507:SF0 UNCHARACTERIZED PRKR-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;RNA binding#GO:0003723;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;double-stranded RNA binding#GO:0003725;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;protein phosphorylation#GO:0006468;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25566|UniProtKB=Q9C0A6 Q9C0A6 SETD5 PTHR46462:SF1 UPSET, ISOFORM A HISTONE-LYSINE N-METHYLTRANSFERASE SETD5 HUMAN|HGNC=20670|UniProtKB=Q8WVJ9 Q8WVJ9 TWIST2 PTHR23349:SF70 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TWIST-RELATED PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=26252|UniProtKB=Q5VTH9 Q5VTH9 WDR78 PTHR12442:SF12 DYNEIN INTERMEDIATE CHAIN WD REPEAT-CONTAINING PROTEIN 78 dynein heavy chain binding#GO:0045504;protein binding#GO:0005515;binding#GO:0005488 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement#GO:0003341 supramolecular complex#GO:0099080;axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=2697|UniProtKB=Q10586 Q10586 DBP PTHR11988:SF7 THYROTROPH EMBRYONIC FACTOR RELATED D SITE-BINDING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=2898|UniProtKB=P09622 P09622 DLD PTHR22912:SF151 DISULFIDE OXIDOREDUCTASE DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL nucleotide binding#GO:0000166;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxidation-reduction process#GO:0055114;metabolic process#GO:0008152 oxidoreductase#PC00176 HUMAN|HGNC=5906|UniProtKB=A0A075B6J6 A0A075B6J6 IGLV3-22 PTHR23267:SF359 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-22 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=37273|UniProtKB=B4DU55 B4DU55 ZNF879 PTHR24377:SF626 IP01015P-RELATED ZINC FINGER PROTEIN 879 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2846|UniProtKB=Q14129 Q14129 DGCR6 PTHR13054:SF7 DIGEORGE SYNDROME CRITICAL REGION 6 DGCR6 FAMILY MEMBER PROTEIN DGCR6 HUMAN|HGNC=919|UniProtKB=O96024 O96024 B3GALT4 PTHR11214:SF345 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 4 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;cellular polysaccharide biosynthetic process#GO:0033692;cellular polysaccharide metabolic process#GO:0044264;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=200|UniProtKB=Q9UKJ8 Q9UKJ8 ADAM21 PTHR11905:SF116 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 21 developmental process involved in reproduction#GO:0003006;reproductive system development#GO:0061458;system development#GO:0048731;reproduction#GO:0000003;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;sex differentiation#GO:0007548;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;male gonad development#GO:0008584;male sex differentiation#GO:0046661;reproductive structure development#GO:0048608 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=14161|UniProtKB=Q9BV90 Q9BV90 SNRNP25 PTHR14942:SF0 U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN HUMAN|HGNC=23447|UniProtKB=Q5VT03 Q5VT03 NUTM2D PTHR22879:SF14 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 2A-RELATED HUMAN|HGNC=19856|UniProtKB=Q52LA3 Q52LA3 LIN52 PTHR31489:SF2 LIN52 FAMILY MEMBER PROTEIN LIN-52 HOMOLOG HUMAN|HGNC=27316|UniProtKB=Q6PJ69 Q6PJ69 TRIM65 PTHR25465:SF29 FAMILY NOT NAMED TRIPARTITE MOTIF-CONTAINING PROTEIN 65 regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;cellular metabolic process#GO:0044237;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;positive regulation of metabolic process#GO:0009893;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;catabolic process#GO:0009056;positive regulation of autophagy#GO:0010508;positive regulation of biological process#GO:0048518;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;cellular catabolic process#GO:0044248;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 HUMAN|HGNC=3064|UniProtKB=P28562 P28562 DUSP1 PTHR10159:SF309 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;phosphoprotein phosphatase activity#GO:0004721;kinase activity#GO:0016301;kinase binding#GO:0019900;phosphoric ester hydrolase activity#GO:0042578;protein kinase activity#GO:0004672;transferase activity#GO:0016740;MAP kinase activity#GO:0004707;hydrolase activity#GO:0016787;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;ectoderm formation#GO:0001705;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;negative regulation of MAPK cascade#GO:0043409;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;mesoderm morphogenesis#GO:0048332;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;regulation of MAP kinase activity#GO:0043405;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;ectoderm development#GO:0007398;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;stress-activated protein kinase signaling cascade#GO:0031098;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;embryo development#GO:0009790;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;mesoderm formation#GO:0001707;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of signaling#GO:0023051;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;endoderm formation#GO:0001706;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;negative regulation of protein kinase activity#GO:0006469;negative regulation of transferase activity#GO:0051348;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;negative regulation of MAP kinase activity#GO:0043407;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;mesoderm development#GO:0007498;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;formation of primary germ layer#GO:0001704;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;tissue morphogenesis#GO:0048729;embryonic morphogenesis#GO:0048598;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131;Gonadotropin-releasing hormone receptor pathway#P06664>DUSP1#P06823;p38 MAPK pathway#P05918>MKP1#P05922 HUMAN|HGNC=4629|UniProtKB=O15217 O15217 GSTA4 PTHR11571:SF123 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE A4 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;sulfur compound metabolic process#GO:0006790;cellular response to chemical stimulus#GO:0070887;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;response to stimulus#GO:0050896;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=5117|UniProtKB=P17509 P17509 HOXB6 PTHR45659:SF9 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-B6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=21390|UniProtKB=Q5TAB7 Q5TAB7 RIPPLY2 PTHR16770:SF3 FAMILY NOT NAMED PROTEIN RIPPLY2 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=1365|UniProtKB=Q9UGQ2 Q9UGQ2 CACFD1 PTHR13314:SF2 UNCHARACTERIZED CALCIUM CHANNEL FLOWER HOMOLOG localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 HUMAN|HGNC=5997|UniProtKB=Q9NP60 Q9NP60 IL1RAPL2 PTHR11890:SF10 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER X-LINKED INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN-LIKE 2 transmembrane signal receptor#PC00197 HUMAN|HGNC=24077|UniProtKB=Q9UM13 Q9UM13 ANAPC10 PTHR12936:SF3 ANAPHASE-PROMOTING COMPLEX 10 ANAPHASE-PROMOTING COMPLEX SUBUNIT 10 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein K11-linked ubiquitination#GO:0070979;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Cell cycle#P00013>APC#P00481 HUMAN|HGNC=16784|UniProtKB=Q9BZQ8 Q9BZQ8 NIBAN1 PTHR14392:SF3 NIBAN FAMILY MEMBER PROTEIN NIBAN 1 HUMAN|HGNC=25195|UniProtKB=Q6PEV8 Q6PEV8 FAM199X PTHR32003:SF1 PROTEIN FAM199X PROTEIN FAM199X HUMAN|HGNC=12976|UniProtKB=O15231 O15231 ZNF185 PTHR15468:SF2 ZNF185 ZINC FINGER PROTEIN 185 HUMAN|HGNC=13927|UniProtKB=Q6UXA7 Q6UXA7 C6orf15 PTHR15817:SF2 STG PROTEIN MUCIN 18B, ISOFORM A HUMAN|HGNC=30464|UniProtKB=Q96CN4 Q96CN4 EVI5L PTHR22957:SF254 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN EVI5-LIKE PROTEIN GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=17748|UniProtKB=Q9NYF0 Q9NYF0 DACT1 PTHR15919:SF12 DAPPER-RELATED DAPPER HOMOLOG 1 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;negative regulation of MAPK cascade#GO:0043409;anatomical structure morphogenesis#GO:0009653;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;cellular protein metabolic process#GO:0044267;JNK cascade#GO:0007254;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;cell-cell signaling by wnt#GO:0198738;stress-activated protein kinase signaling cascade#GO:0031098;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;epithelium development#GO:0060429;animal organ development#GO:0048513;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;non-canonical Wnt signaling pathway#GO:0035567;developmental process#GO:0032502;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;establishment of planar polarity#GO:0001736;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;regulation of canonical Wnt signaling pathway#GO:0060828;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;negative regulation of phosphorylation#GO:0042326;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;morphogenesis of an epithelium#GO:0002009;negative regulation of canonical Wnt signaling pathway#GO:0090090 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Wnt signaling pathway#P00057>Frodo#P01470;Wnt signaling pathway#P00057>Dapper#P01469 HUMAN|HGNC=24993|UniProtKB=Q86X83 Q86X83 COMMD2 PTHR15857:SF0 COMM DOMAIN CONTAINING PROTEIN 2 COMM DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=30670|UniProtKB=Q496J9 Q496J9 SV2C PTHR23511:SF6 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2C bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=4077|UniProtKB=P34903 P34903 GABRA3 PTHR18945:SF216 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-3 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;cell junction#GO:0030054;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=2088|UniProtKB=O76031 O76031 CLPX PTHR48102:SF7 ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;ATP binding#GO:0005524;ATPase activity#GO:0016887 macromolecule catabolic process#GO:0009057;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;organonitrogen compound catabolic process#GO:1901565;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 HUMAN|HGNC=7684|UniProtKB=O95299 O95299 NDUFA10 PTHR10513:SF15 DEOXYNUCLEOSIDE KINASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;kinase activity#GO:0016301;catalytic activity#GO:0003824 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 nucleotide kinase#PC00172 HUMAN|HGNC=19439|UniProtKB=Q7Z418 Q7Z418 KCNK18 PTHR11003:SF158 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 18 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=20370|UniProtKB=Q8N6K0 Q8N6K0 TEX29 PTHR37339:SF1 TESTIS-EXPRESSED PROTEIN 29 TESTIS-EXPRESSED PROTEIN 29 HUMAN|HGNC=28368|UniProtKB=Q9BUU2 Q9BUU2 METTL22 PTHR23108:SF0 METHYLTRANSFERASE-RELATED METHYLTRANSFERASE-LIKE PROTEIN 22 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 methyltransferase#PC00155 HUMAN|HGNC=916|UniProtKB=Q9Y5Z6 Q9Y5Z6 B3GALT1 PTHR11214:SF20 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=20398|UniProtKB=A6NH52 A6NH52 TVP23A PTHR13019:SF18 UNCHARACTERIZED GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG A macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=12872|UniProtKB=Q15915 Q15915 ZIC1 PTHR19818:SF141 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6015|UniProtKB=P24394 P24394 IL4R PTHR23037:SF32 CYTOKINE RECEPTOR INTERLEUKIN-4 RECEPTOR SUBUNIT ALPHA transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=26724|UniProtKB=Q68DC2 Q68DC2 ANKS6 PTHR10627:SF70 SCP160 ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 6 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=29574|UniProtKB=Q86XK3 Q86XK3 SFR1 PTHR28643:SF1 SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG transcription coactivator activity#GO:0003713;nuclear receptor transcription coactivator activity#GO:0030374;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 DNA repair#GO:0006281;positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 HUMAN|HGNC=6727|UniProtKB=Q16553 Q16553 LY6E PTHR16983:SF13 UPAR/LY6 DOMAIN-CONTAINING PROTEIN LYMPHOCYTE ANTIGEN 6E HUMAN|HGNC=33715|UniProtKB=Q6ZUX3 Q6ZUX3 TOGARAM2 PTHR21567:SF42 CLASP TOG ARRAY REGULATOR OF AXONEMAL MICROTUBULES PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=13538|UniProtKB=Q96L34 Q96L34 MARK4 PTHR24346:SF28 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MAP/MICROTUBULE AFFINITY-REGULATING KINASE 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=11504|UniProtKB=O15056 O15056 SYNJ2 PTHR11200:SF148 INOSITOL 5-PHOSPHATASE SYNAPTOJANIN-2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;head development#GO:0060322;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;animal organ development#GO:0048513;transport#GO:0006810;developmental process#GO:0032502;brain development#GO:0007420;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;glycerolipid metabolic process#GO:0046486;membrane invagination#GO:0010324;establishment of localization#GO:0051234;catabolic process#GO:0009056;vesicle organization#GO:0016050;central nervous system development#GO:0007417;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;phospholipid dephosphorylation#GO:0046839;endocytosis#GO:0006897;multicellular organism development#GO:0007275;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;small molecule catabolic process#GO:0044282;vesicle budding from membrane#GO:0006900;cellular carbohydrate metabolic process#GO:0044262;organelle organization#GO:0006996;anatomical structure development#GO:0048856;dephosphorylation#GO:0016311;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;vesicle-mediated transport in synapse#GO:0099003;small molecule metabolic process#GO:0044281 cell junction#GO:0030054;cytoplasm#GO:0005737;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=30417|UniProtKB=Q9NRF2 Q9NRF2 SH2B1 PTHR10872:SF3 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 1 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=719|UniProtKB=P51690 P51690 ARSL PTHR42693:SF5 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE L hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=6335|UniProtKB=Q14952 Q14952 KIR2DS3 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=9507|UniProtKB=A5PKW4 A5PKW4 PSD PTHR10663:SF334 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=29368|UniProtKB=Q9C0B2 Q9C0B2 CFAP74 PTHR22538:SF0 UNCHARACTERIZED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 74 HUMAN|HGNC=30412|UniProtKB=Q8WTS6 Q8WTS6 SETD7 PTHR46820:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD7 HISTONE-LYSINE N-METHYLTRANSFERASE SETD7 histone modifying enzyme#PC00261 HUMAN|HGNC=17025|UniProtKB=Q96P44 Q96P44 COL21A1 PTHR24020:SF20 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXI) CHAIN extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=750|UniProtKB=P46597 P46597 ASMT PTHR11746:SF254 O-METHYLTRANSFERASE ACETYLSEROTONIN O-METHYLTRANSFERASE methyltransferase#PC00155 HUMAN|HGNC=25667|UniProtKB=Q9HAI6 Q9HAI6 CXorf21 PTHR14889:SF3 RCG36411 PROTEIN CXORF21 lysosome organization#GO:0007040;regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;cellular component organization or biogenesis#GO:0071840;regulation of pH#GO:0006885;vacuole organization#GO:0007033;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 HUMAN|HGNC=13743|UniProtKB=Q9BYJ1 Q9BYJ1 ALOXE3 PTHR11771:SF184 LIPOXYGENASE HYDROPEROXIDE ISOMERASE ALOXE3 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;oxidation-reduction process#GO:0055114;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxygenase#PC00177 HUMAN|HGNC=10241|UniProtKB=Q9H814 Q9H814 PHAX PTHR13135:SF0 CYTOSOLIC RESINIFERATOXIN BINDING PROTEIN RBP-26 PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN RNA metabolism protein#PC00031 HUMAN|HGNC=9273|UniProtKB=O60437 O60437 PPL PTHR23169:SF10 ENVOPLAKIN PERIPLAKIN cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;wound healing#GO:0042060;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intracellular#GO:0005622;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 intermediate filament binding protein#PC00130 HUMAN|HGNC=19967|UniProtKB=Q9P219 Q9P219 CCDC88C PTHR18947:SF31 HOOK PROTEINS PROTEIN DAPLE cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 membrane traffic protein#PC00150 HUMAN|HGNC=19841|UniProtKB=Q6SJ96 Q6SJ96 TBPL2 PTHR10126:SF37 TATA-BOX BINDING PROTEIN TATA BOX-BINDING PROTEIN-LIKE 2 transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;RNA polymerase II general transcription initiation factor activity#GO:0016251 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 HUMAN|HGNC=21709|UniProtKB=Q9BVT8 Q9BVT8 TMUB1 PTHR14557:SF3 PROTEIN C7ORF21 TRANSMEMBRANE AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN 1 cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 HUMAN|HGNC=8765|UniProtKB=O75340 O75340 PDCD6 PTHR23064:SF41 TROPONIN PROGRAMMED CELL DEATH PROTEIN 6 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=26890|UniProtKB=Q8N2M4 Q8N2M4 TMEM86A PTHR31885:SF9 GH04784P LYSOPLASMALOGENASE-LIKE PROTEIN TMEM86A hydrolase activity#GO:0016787;catalytic activity#GO:0003824 HUMAN|HGNC=12340|UniProtKB=Q9UHF7 Q9UHF7 TRPS1 PTHR47034:SF1 ZINC FINGER TRANSCRIPTION FACTOR TRPS1 ZINC FINGER TRANSCRIPTION FACTOR TRPS1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;organic cyclic compound binding#GO:0097159;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;regulation of apoptotic signaling pathway#GO:2001233;nucleobase-containing compound metabolic process#GO:0006139;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of response to stimulus#GO:0048584;organic cyclic compound metabolic process#GO:1901360;positive regulation of programmed cell death#GO:0043068;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;cell death#GO:0008219;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;connective tissue development#GO:0061448;chondrocyte differentiation#GO:0002062;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;extrinsic apoptotic signaling pathway#GO:0097191;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of nucleic acid-templated transcription#GO:1903506;cartilage development#GO:0051216;positive regulation of cell death#GO:0010942;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=25176|UniProtKB=Q96MX6 Q96MX6 WDR92 PTHR10971:SF2 MRNA EXPORT FACTOR AND BUB3 WD REPEAT-CONTAINING PROTEIN 92 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 RNA metabolism protein#PC00031 HUMAN|HGNC=30793|UniProtKB=O60841 O60841 EIF5B PTHR43381:SF4 TRANSLATION INITIATION FACTOR IF-2-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 5B translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159 translation initiation factor#PC00224 HUMAN|HGNC=26851|UniProtKB=Q8NDH2 Q8NDH2 CCDC168 PTHR35542:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 168 COILED-COIL DOMAIN-CONTAINING PROTEIN 168 HUMAN|HGNC=28486|UniProtKB=Q8NHS3 Q8NHS3 MFSD8 PTHR23510:SF3 INNER MEMBRANE TRANSPORT PROTEIN YAJR MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 8 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=6846|UniProtKB=P52564 P52564 MAP2K6 PTHR48013:SF12 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 non-receptor serine/threonine protein kinase#PC00167 p38 MAPK pathway#P05918>MKK6#P06032;Oxidative stress response#P00046>MKK3/6#P01121;Gonadotropin-releasing hormone receptor pathway#P06664>MKK3/6#P06805;FGF signaling pathway#P00021>MKK3,6#P00625;EGF receptor signaling pathway#P00018>MKK3,6#P00540;Ras Pathway#P04393>MKK3/6#P04568;CCKR signaling map#P06959>MAP2K6#P07233 HUMAN|HGNC=22947|UniProtKB=Q8WX94 Q8WX94 NLRP7 PTHR45690:SF14 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 7 HUMAN|HGNC=29190|UniProtKB=Q9UPQ9 Q9UPQ9 TNRC6B PTHR13020:SF32 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6B PROTEIN negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;posttranscriptional gene silencing#GO:0016441;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;gene silencing by miRNA#GO:0035195;nuclear-transcribed mRNA catabolic process#GO:0000956;gene silencing by RNA#GO:0031047;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254;cellular macromolecule catabolic process#GO:0044265 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=18737|UniProtKB=Q9H8N7 Q9H8N7 ZNF395 PTHR13006:SF6 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 ZINC FINGER PROTEIN 395 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=8794|UniProtKB=O95263 O95263 PDE8B PTHR11347:SF98 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8B hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 phosphodiesterase#PC00185 HUMAN|HGNC=1851|UniProtKB=P49450 P49450 CENPA PTHR11426:SF191 HISTONE H3 HISTONE H3-LIKE CENTROMERIC PROTEIN A histone#PC00118 HUMAN|HGNC=670|UniProtKB=O00212 O00212 RHOD PTHR24072:SF175 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOD GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 small GTPase#PC00208 HUMAN|HGNC=9988|UniProtKB=O00287 O00287 RFXAP PTHR15110:SF2 REGULATORY FACTOR X-ASSOCIATED PROTEIN REGULATORY FACTOR X-ASSOCIATED PROTEIN cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=15573|UniProtKB=Q9Y6X0 Q9Y6X0 SETBP1 PTHR46147:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 SET-BINDING PROTEIN histone modifying enzyme#PC00261 HUMAN|HGNC=24607|UniProtKB=Q86VF2 Q86VF2 IGFN1 PTHR13817:SF138 TITIN IMMUNOGLOBULIN-LIKE AND FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=16232|UniProtKB=Q96KJ9 Q96KJ9 COX4I2 PTHR10707:SF11 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 2, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;aerobic electron transport chain#GO:0019646;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277 oxidase#PC00175 HUMAN|HGNC=9018|UniProtKB=Q9C010 Q9C010 PKIB PTHR15416:SF6 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI CAMP-DEPENDENT PROTEIN KINASE INHIBITOR BETA carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;protein phosphorylation#GO:0006468;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase inhibitor#PC00139 HUMAN|HGNC=21113|UniProtKB=Q6UY11 Q6UY11 DLK2 PTHR24044:SF423 NOTCH LIGAND FAMILY MEMBER PROTEIN DELTA HOMOLOG 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 HUMAN|HGNC=3657|UniProtKB=P07332 P07332 FES PTHR24418:SF197 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FES/FPS protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;lysosome localization#GO:0032418;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;secretion#GO:0046903;regulation of secretion#GO:0051046;innate immune response#GO:0045087;positive regulation of immune effector process#GO:0002699;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;leukocyte activation#GO:0045321;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of cellular localization#GO:0060341;cell activation involved in immune response#GO:0002263;exocytic process#GO:0140029;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;exocytosis#GO:0006887;leukocyte activation involved in immune response#GO:0002366;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;locomotion#GO:0040011;export from cell#GO:0140352;taxis#GO:0042330;vesicle fusion#GO:0006906;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;biological adhesion#GO:0022610;developmental process#GO:0032502;transport#GO:0006810;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;regulation of transport#GO:0051049;protein autophosphorylation#GO:0046777;vesicle organization#GO:0016050;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;chemotaxis#GO:0006935;metabolic process#GO:0008152;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of immune effector process#GO:0002697;response to external stimulus#GO:0009605;regulation of leukocyte activation#GO:0002694;membrane fusion#GO:0061025;peptidyl-tyrosine modification#GO:0018212;response to chemical#GO:0042221;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;establishment of localization in cell#GO:0051649 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 Axon guidance mediated by semaphorins#P00007>Fes#P00332 HUMAN|HGNC=30457|UniProtKB=A6NED2 A6NED2 RCCD1 PTHR46849:SF1 RCC1 DOMAIN-CONTAINING PROTEIN 1 RCC1 DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=29032|UniProtKB=O43304 O43304 SEC14L5 PTHR23324:SF39 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 5 HUMAN|HGNC=5804|UniProtKB=P01614 P01614 IGKV2D-40 PTHR23267:SF381 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-40-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|Ensembl=ENSG00000214978|UniProtKB=A8MUP6 A8MUP6 GSG1L2 PTHR10671:SF40 EPITHELIAL MEMBRANE PROTEIN-RELATED GERM CELL-SPECIFIC GENE 1-LIKE PROTEIN 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=4557|UniProtKB=O75715 O75715 GPX5 PTHR11592:SF127 GLUTATHIONE PEROXIDASE EPIDIDYMAL SECRETORY GLUTATHIONE PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180 HUMAN|HGNC=25300|UniProtKB=Q6PCT2 Q6PCT2 FBXL19 PTHR23123:SF35 PHD/F-BOX CONTAINING PROTEIN F-BOX/LRR-REPEAT PROTEIN 19 molecular function regulator#GO:0098772;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;demethylation#GO:0070988;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein demethylation#GO:0006482;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=2928|UniProtKB=P11532 P11532 DMD PTHR11915:SF426 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN DYSTROPHIN HUMAN|HGNC=32971|UniProtKB=Q6A163 Q6A163 KRT39 PTHR23239:SF106 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 39 HUMAN|HGNC=25706|UniProtKB=Q6PJI9 Q6PJI9 WDR59 PTHR46170:SF1 GATOR COMPLEX PROTEIN WDR59 GATOR COMPLEX PROTEIN WDR59 HUMAN|HGNC=19961|UniProtKB=Q9UNK9 Q9UNK9 ANGEL1 PTHR12121:SF28 CARBON CATABOLITE REPRESSOR PROTEIN 4 PROTEIN ANGEL HOMOLOG 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;catalytic activity#GO:0003824;ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=14299|UniProtKB=Q9H228 Q9H228 S1PR5 PTHR22750:SF20 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=30715|UniProtKB=Q7RTY9 Q7RTY9 PRSS41 PTHR24253:SF79 TRANSMEMBRANE PROTEASE SERINE SERINE PROTEASE 41 serine protease#PC00203 HUMAN|HGNC=2951|UniProtKB=Q9C0G6 Q9C0G6 DNAH6 PTHR10676:SF339 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN 6, AXONEMAL pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;cellular process#GO:0009987;microtubule-based process#GO:0007017 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=4993|UniProtKB=B2RPK0 B2RPK0 HMGB1P1 PTHR48112:SF4 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B1-LIKE 1-RELATED heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;DNA binding, bending#GO:0008301;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=30620|UniProtKB=Q9GZP0 Q9GZP0 PDGFD PTHR11633:SF4 PLATELET-DERIVED GROWTH FACTOR PLATELET-DERIVED GROWTH FACTOR D growth factor receptor binding#GO:0070851;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component movement#GO:0051272;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;inositol lipid-mediated signaling#GO:0048017;positive regulation of ERK1 and ERK2 cascade#GO:0070374;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell motility#GO:2000147;regulation of protein serine/threonine kinase activity#GO:0071900;protein autophosphorylation#GO:0046777;phosphatidylinositol-mediated signaling#GO:0048015;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;ERK1 and ERK2 cascade#GO:0070371;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of cell migration#GO:0030335;phosphatidylinositol 3-kinase signaling#GO:0014065;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of phosphatidylinositol 3-kinase signaling#GO:0014066;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477;regulation of transferase activity#GO:0051338 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Angiogenesis#P00005>PDGF#P00224 HUMAN|HGNC=26267|UniProtKB=Q9H5K3 Q9H5K3 POMK PTHR22618:SF2 UNCHARACTERIZED PROTEIN O-MANNOSE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;protein O-linked glycosylation#GO:0006493;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;cellular carbohydrate metabolic process#GO:0044262;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=24911|UniProtKB=Q96HH9 Q96HH9 GRAMD2B PTHR46645:SF2 GRAM DOMAIN-CONTAINING PROTEIN 2B-RELATED GRAM DOMAIN-CONTAINING PROTEIN 2B HUMAN|HGNC=18867|UniProtKB=A8MYU2 A8MYU2 KCNU1 PTHR10027:SF23 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY U MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;ion channel activity#GO:0005216;potassium ion transmembrane transporter activity#GO:0015079;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;transporter activity#GO:0005215;channel activity#GO:0015267;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 reproductive process#GO:0022414;reproduction#GO:0000003 synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=14922|UniProtKB=Q9HDD0 Q9HDD0 PLAAT1 PTHR13943:SF37 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 1 transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=29119|UniProtKB=O94888 O94888 UBXN7 PTHR23322:SF6 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 7 HUMAN|HGNC=33874|UniProtKB=Q6DKI2 Q6DKI2 LGALS9C PTHR11346:SF91 GALECTIN GALECTIN-9C carbohydrate derivative binding#GO:0097367;carbohydrate binding#GO:0030246;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of biological process#GO:0048519;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;gene expression#GO:0010467;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;cytokine production#GO:0001816;leukocyte cell-cell adhesion#GO:0007159;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;negative regulation of multicellular organismal process#GO:0051241;T cell proliferation#GO:0042098;positive regulation of metabolic process#GO:0009893;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;negative regulation of cell population proliferation#GO:0008285;regulation of gene expression#GO:0010468;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;negative regulation of T cell proliferation#GO:0042130;regulation of multicellular organismal process#GO:0051239;lymphocyte activation#GO:0046649;regulation of cell population proliferation#GO:0042127;negative regulation of T cell activation#GO:0050868;macromolecule metabolic process#GO:0043170;cell-cell adhesion#GO:0098609;negative regulation of metabolic process#GO:0009892;lymphocyte proliferation#GO:0046651;cell adhesion#GO:0007155;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;regulation of T cell proliferation#GO:0042129;negative regulation of cell adhesion#GO:0007162;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;regulation of macromolecule metabolic process#GO:0060255;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;multicellular organismal process#GO:0032501;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250;regulation of leukocyte proliferation#GO:0070663;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 extracellular matrix protein#PC00102 HUMAN|HGNC=29213|UniProtKB=Q8WUJ3 Q8WUJ3 CEMIP PTHR15535:SF15 TRANSMEMBRANE PROTEIN 2-RELATED CELL MIGRATION-INDUCING AND HYALURONAN-BINDING PROTEIN HUMAN|HGNC=26535|UniProtKB=Q5VXU9 Q5VXU9 SHOC1 PTHR35668:SF1 PROTEIN SHORTAGE IN CHIASMATA 1 ORTHOLOG PROTEIN SHORTAGE IN CHIASMATA 1 ORTHOLOG pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;meiotic chromosome separation#GO:0051307;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=20068|UniProtKB=Q9H9J4 Q9H9J4 USP42 PTHR24006:SF727 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 42 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=29996|UniProtKB=Q8TAE8 Q8TAE8 GADD45GIP1 PTHR31761:SF1 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEINS-INTERACTING PROTEIN 1 GADD45GIP1 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEINS-INTERACTING PROTEIN 1 negative regulation of biological process#GO:0048519;negative regulation of cell cycle#GO:0045786;nuclear division#GO:0000280;cell cycle process#GO:0022402;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cell cycle arrest#GO:0007050;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346 HUMAN|HGNC=30136|UniProtKB=Q96B96 Q96B96 TMEM159 PTHR14275:SF0 PROMETHIN LIPID DROPLET ASSEMBLY FACTOR 1 HUMAN|HGNC=5647|UniProtKB=A0A087WSY4 A0A087WSY4 IGHV4-30-2 PTHR23266:SF323 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=4029|UniProtKB=Q96DB9 Q96DB9 FXYD5 PTHR14132:SF14 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 5 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of sodium ion transport#GO:0002028;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;sodium ion transport#GO:0006814;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;sodium ion transmembrane transport#GO:0035725 primary active transporter#PC00068 HUMAN|HGNC=15359|UniProtKB=P0C623 P0C623 OR4Q2 PTHR48002:SF127 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4Q2 transmembrane signal receptor#PC00197 HUMAN|HGNC=31293|UniProtKB=A6NF89 A6NF89 OR6C6 PTHR26454:SF40 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=19070|UniProtKB=Q96FV9 Q96FV9 THOC1 PTHR13265:SF2 THO COMPLEX SUBUNIT 1 THO COMPLEX SUBUNIT 1 cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;nuclear export#GO:0051168;regulation of cellular process#GO:0050794;protein transport#GO:0015031;aromatic compound biosynthetic process#GO:0019438;intracellular transport#GO:0046907;regulation of metabolic process#GO:0019222;protein-containing complex localization#GO:0031503;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nucleic acid transport#GO:0050657;biosynthetic process#GO:0009058;ribonucleoprotein complex export from nucleus#GO:0071426;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of DNA-templated transcription, elongation#GO:0032784;regulation of transcription, DNA-templated#GO:0006355;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;protein export from nucleus#GO:0006611;regulation of macromolecule biosynthetic process#GO:0010556;DNA-templated transcription, elongation#GO:0006354;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;mRNA export from nucleus#GO:0006406;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;ribonucleoprotein complex localization#GO:0071166;organic cyclic compound biosynthetic process#GO:1901362;mRNA transport#GO:0051028;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nucleocytoplasmic transport#GO:0006913;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;regulation of nucleic acid-templated transcription#GO:1903506;RNA export from nucleus#GO:0006405;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=7960|UniProtKB=P51843 P51843 NR0B1 PTHR24081:SF1 NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B MEMBER 1 molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of molecular function#GO:0044092;negative regulation of DNA-binding transcription factor activity#GO:0043433 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=21405|UniProtKB=Q8IYR0 Q8IYR0 CFAP206 PTHR21442:SF0 UNCHARACTERIZED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206 HUMAN|HGNC=4455|UniProtKB=P21695 P21695 GPD1 PTHR11728:SF32 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)], CYTOPLASMIC catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 carbohydrate derivative metabolic process#GO:1901135;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=6269|UniProtKB=Q15842 Q15842 KCNJ8 PTHR11767:SF11 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 8 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=640|UniProtKB=O14520 O14520 AQP7 PTHR43829:SF15 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-7 amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 HUMAN|HGNC=359|UniProtKB=Q9NZN9 Q9NZN9 AIPL1 PTHR11242:SF2 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED ARYL-HYDROCARBON-INTERACTING PROTEIN-LIKE 1 chaperone#PC00072 HUMAN|HGNC=25033|UniProtKB=Q8WZ04 Q8WZ04 LRTOMT PTHR43836:SF1 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE 2-RELATED methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;catecholamine metabolic process#GO:0006584;cellular process#GO:0009987;organic cyclic compound metabolic process#GO:1901360;aromatic compound catabolic process#GO:0019439;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 methyltransferase#PC00155 HUMAN|HGNC=21745|UniProtKB=Q7Z5Q1 Q7Z5Q1 CPEB2 PTHR12566:SF8 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 2 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 synapse#GO:0045202;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=16822|UniProtKB=P78312 P78312 FAM193A PTHR15109:SF2 AGAP004327-PA PROTEIN FAM193A HUMAN|HGNC=16461|UniProtKB=Q9Y2W2 Q9Y2W2 WBP11 PTHR13361:SF4 WW DOMAIN-BINDING PROTEIN 11 WW DOMAIN-BINDING PROTEIN 11 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA cis splicing, via spliceosome#GO:0045292;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=30691|UniProtKB=Q8NFY9 Q8NFY9 KBTBD8 PTHR24412:SF433 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 8 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9620|UniProtKB=Q12792 Q12792 TWF1 PTHR13759:SF8 TWINFILIN TWINFILIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of multicellular organismal process#GO:0051239;regulation of organelle organization#GO:0033043;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cellular macromolecule localization#GO:0070727;positive regulation of neurogenesis#GO:0050769;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;negative regulation of actin filament polymerization#GO:0030837;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;plasma membrane bounded cell projection assembly#GO:0120031;positive regulation of multicellular organismal process#GO:0051240;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;macromolecule localization#GO:0033036;positive regulation of cell projection organization#GO:0031346;cellular protein localization#GO:0034613;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;cellular component disassembly#GO:0022411;regulation of protein-containing complex assembly#GO:0043254;negative regulation of organelle organization#GO:0010639;supramolecular fiber organization#GO:0097435;neuron differentiation#GO:0030182;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;regulation of anatomical structure size#GO:0090066;positive regulation of neuron differentiation#GO:0045666;regulation of cell development#GO:0060284;positive regulation of cell differentiation#GO:0045597;regulation of actin filament length#GO:0030832;multicellular organism development#GO:0007275;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;positive regulation of developmental process#GO:0051094;cell projection assembly#GO:0030031;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;cell development#GO:0048468;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;maintenance of location in cell#GO:0051651;regulation of cell projection assembly#GO:0060491;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856;myofibril#GO:0030016 non-motor actin binding protein#PC00165 HUMAN|HGNC=4443|UniProtKB=P40197 P40197 GP5 PTHR45617:SF38 LEUCINE RICH REPEAT FAMILY PROTEIN PLATELET GLYCOPROTEIN V Blood coagulation#P00011>GP V#P00420 HUMAN|HGNC=1136|UniProtKB=Q7KYR7 Q7KYR7 BTN2A1 PTHR24100:SF79 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 2 MEMBER A1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=23225|UniProtKB=Q8N0X2 Q8N0X2 SPAG16 PTHR14604:SF3 WD40 REPEAT PF20 SPERM-ASSOCIATED ANTIGEN 16 PROTEIN microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=18327|UniProtKB=P61236 P61236 YPEL3 PTHR13848:SF6 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 3 HUMAN|Gene=F231L_HUMAN|UniProtKB=P0DMU3 P0DMU3 - PTHR40715:SF1 FAM231A/C-LIKE PROTEIN LOC102723383 FAM231A/C-LIKE PROTEIN LOC102723383 HUMAN|HGNC=21576|UniProtKB=Q6VVB1 Q6VVB1 NHLRC1 PTHR24104:SF34 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED E3 UBIQUITIN-PROTEIN LIGASE NHLRC1 translation regulator activity#GO:0045182;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;gene expression#GO:0010467;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;regulation of cellular amide metabolic process#GO:0034248;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=15426|UniProtKB=Q8NH05 Q8NH05 OR4Q3 PTHR48002:SF112 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4Q3 transmembrane signal receptor#PC00197 HUMAN|HGNC=10973|UniProtKB=Q9UGH3 Q9UGH3 SLC23A2 PTHR11119:SF33 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 2 oxoacid metabolic process#GO:0043436;monosaccharide metabolic process#GO:0005996;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;carbohydrate metabolic process#GO:0005975;organic acid metabolic process#GO:0006082;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 transporter#PC00227 HUMAN|HGNC=6238|UniProtKB=Q9NZV8 Q9NZV8 KCND2 PTHR11537:SF265 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=29295|UniProtKB=O60812 O60812 HNRNPCL1 PTHR13968:SF17 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN C-LIKE 1-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=11608|UniProtKB=P21731 P21731 TBXA2R PTHR11866:SF5 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER THROMBOXANE A2 RECEPTOR signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;organic acid binding#GO:0043177;transmembrane signaling receptor activity#GO:0004888 blood circulation#GO:0008015;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of cyclase activity#GO:0031279;system process#GO:0003008;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of blood vessel diameter#GO:0097746;regulation of system process#GO:0044057;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of intracellular signal transduction#GO:1902531;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of anatomical structure size#GO:0090066;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular cation homeostasis#GO:0030003;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;circulatory system process#GO:0003013;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to stress#GO:0006950;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;positive regulation of blood pressure#GO:0045777;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935;positive regulation of multicellular organismal process#GO:0051240 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=16275|UniProtKB=Q9C037 Q9C037 TRIM4 PTHR24103:SF658 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM4 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=7517|UniProtKB=Q6W4X9 Q6W4X9 MUC6 PTHR11339:SF264 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-6 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=15913|UniProtKB=Q9UKK6 Q9UKK6 NXT1 PTHR12612:SF4 NUCLEAR TRANSPORT FACTOR 2 NTF2-RELATED EXPORT PROTEIN 1 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear pore central transport channel#GO:0044613;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=3325|UniProtKB=P41970 P41970 ELK3 PTHR11849:SF172 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 Interleukin signaling pathway#P00036>ELK#P00962 HUMAN|HGNC=17223|UniProtKB=Q9Y2C2 Q9Y2C2 UST PTHR12129:SF15 HEPARAN SULFATE 2-O-SULFOTRANSFERASE URONYL 2-SULFOTRANSFERASE transferase#PC00220 HUMAN|HGNC=4943|UniProtKB=P01906 P01906 HLA-DQA2 PTHR19944:SF94 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ ALPHA 2 CHAIN major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 HUMAN|HGNC=5479|UniProtKB=P01877 P01877 IGHA2 PTHR23266:SF68 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY CONSTANT ALPHA 1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=19873|UniProtKB=Q86SR1 Q86SR1 GALNT10 PTHR11675:SF41 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 10 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=28361|UniProtKB=Q9BW62 Q9BW62 KATNAL1 PTHR23074:SF65 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 1 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;ATPase activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=5749|UniProtKB=A0A075B6S4 A0A075B6S4 IGKV1D-17 PTHR23267:SF384 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-16-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=25233|UniProtKB=Q6P499 Q6P499 NIPAL3 PTHR12570:SF14 UNCHARACTERIZED NIPA-LIKE PROTEIN 3 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=5741|UniProtKB=P01602 P01602 IGKV1-5 PTHR23267:SF373 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-5 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=7979|UniProtKB=P08235 P08235 NR3C2 PTHR48092:SF19 KNIRPS-RELATED PROTEIN-RELATED MINERALOCORTICOID RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=28791|UniProtKB=Q8N660 Q8N660 NBPF15 PTHR14199:SF35 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 10-RELATED HUMAN|HGNC=11741|UniProtKB=Q00059 Q00059 TFAM PTHR48112:SF1 HIGH MOBILITY GROUP PROTEIN DSP1 TRANSCRIPTION FACTOR A, MITOCHONDRIAL sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 HUMAN|HGNC=801|UniProtKB=P13637 P13637 ATP1A3 PTHR43294:SF15 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-3 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;potassium ion transport#GO:0006813;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;cellular monovalent inorganic cation homeostasis#GO:0030004;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725;export from cell#GO:0140352 primary active transporter#PC00068 HUMAN|HGNC=3298|UniProtKB=O43432 O43432 EIF4G3 PTHR23253:SF23 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 3 translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=21118|UniProtKB=Q008S8 Q008S8 ECT2L PTHR46857:SF1 EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE HUMAN|HGNC=4263|UniProtKB=P10912 P10912 GHR PTHR23036:SF108 CYTOKINE RECEPTOR GROWTH HORMONE RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;cytokine receptor activity#GO:0004896;binding#GO:0005488;peptide binding#GO:0042277;cytokine binding#GO:0019955;amide binding#GO:0033218;growth factor binding#GO:0019838;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to hormone stimulus#GO:0032870;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of receptor signaling pathway via STAT#GO:1904894;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to peptide hormone#GO:0043434;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to hormone#GO:0009725;receptor signaling pathway via STAT#GO:0097696;peptidyl-tyrosine modification#GO:0018212;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 cytoplasm#GO:0005737;receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=30013|UniProtKB=Q96PD5 Q96PD5 PGLYRP2 PTHR11022:SF66 PEPTIDOGLYCAN RECOGNITION PROTEIN N-ACETYLMURAMOYL-L-ALANINE AMIDASE carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;detection of stimulus#GO:0051606;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830 HUMAN|HGNC=16614|UniProtKB=Q5TCM9 Q5TCM9 LCE5A PTHR23263:SF137 SMALL PROLINE-RICH PROTEIN LATE CORNIFIED ENVELOPE PROTEIN 5A HUMAN|HGNC=29480|UniProtKB=P02750 P02750 LRG1 PTHR45617:SF101 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH ALPHA-2-GLYCOPROTEIN HUMAN|HGNC=21203|UniProtKB=Q8IV45 Q8IV45 UNC5CL PTHR12582:SF41 NETRIN RECEPTOR UNC5 UNC5C-LIKE PROTEIN transmembrane signal receptor#PC00197 HUMAN|HGNC=177|UniProtKB=Q03154 Q03154 ACY1 PTHR45892:SF1 AMINOACYLASE-1 AMINOACYLASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 HUMAN|HGNC=5387|UniProtKB=Q13907 Q13907 IDI1 PTHR10885:SF5 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE 1 isomerase activity#GO:0016853;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 isomerase#PC00135 Cholesterol biosynthesis#P00014>Isopentenyl diphosphate delta-isomerase#P00495 HUMAN|HGNC=14920|UniProtKB=Q9NYV8 Q9NYV8 TAS2R14 PTHR11394:SF23 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 14 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=11577|UniProtKB=Q16635 Q16635 TAZ PTHR12497:SF0 TAZ PROTEIN TAFAZZIN TAFAZZIN transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 acyltransferase#PC00042 HUMAN|HGNC=4636|UniProtKB=Q03013 Q03013 GSTM4 PTHR11571:SF137 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 4 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=11219|UniProtKB=P09486 P09486 SPARC PTHR13866:SF6 SPARC OSTEONECTIN SPARC cation binding#GO:0043169;extracellular matrix binding#GO:0050840;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=24289|UniProtKB=Q9Y6K0 Q9Y6K0 CEPT1 PTHR10414:SF27 ETHANOLAMINEPHOSPHOTRANSFERASE CHOLINE/ETHANOLAMINEPHOSPHOTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=2228|UniProtKB=P21964 P21964 COMT PTHR43836:SF3 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;catecholamine metabolic process#GO:0006584;cellular process#GO:0009987;organic cyclic compound metabolic process#GO:1901360;aromatic compound catabolic process#GO:0019439;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 methyltransferase#PC00155 Dopamine receptor mediated signaling pathway#P05912>COMT#P05944;Adrenaline and noradrenaline biosynthesis#P00001>COMT#P00069 HUMAN|HGNC=13770|UniProtKB=Q8TDY8 Q8TDY8 IGDCC4 PTHR44170:SF5 PROTEIN SIDEKICK IMMUNOGLOBULIN SUPERFAMILY DCC SUBCLASS MEMBER 4 HUMAN|HGNC=11328|UniProtKB=O60232 O60232 ZNRD2 PTHR16537:SF1 SJOEGREN SYNDROME/SCLERODERMA AUTOANTIGEN 1 PROTEIN ZNRD2 HUMAN|HGNC=34530|UniProtKB=A8MZ26 A8MZ26 EFCAB9 PTHR47065:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=26974|UniProtKB=Q8NEN9 Q8NEN9 PDZD8 PTHR21519:SF1 PDZ DOMAIN-CONTAINING PROTEIN 8 PDZ DOMAIN-CONTAINING PROTEIN 8 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28070|UniProtKB=Q5TH74 Q5TH74 STPG1 PTHR21580:SF21 SHIPPO-1-RELATED O(6)-METHYLGUANINE-INDUCED APOPTOSIS 2 apoptotic mitochondrial changes#GO:0008637;membrane organization#GO:0061024;transport#GO:0006810;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of mitochondrial membrane permeability#GO:0046902;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;regulation of membrane permeability#GO:0090559 structural protein#PC00211 HUMAN|HGNC=24040|UniProtKB=Q96A54 Q96A54 ADIPOR1 PTHR20855:SF40 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>AdipoR1/R2#P06706 HUMAN|HGNC=1245|UniProtKB=P02747 P02747 C1QC PTHR15427:SF29 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q SUBCOMPONENT SUBUNIT C HUMAN|HGNC=25369|UniProtKB=Q8N7R1 Q8N7R1 POM121L12 PTHR23193:SF20 NUCLEAR PORE COMPLEX PROTEIN NUP POM121-LIKE PROTEIN 12-RELATED signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=16654|UniProtKB=Q8N5N7 Q8N5N7 MRPL50 PTHR31542:SF1 39A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L50, MITOCHONDRIAL membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=18654|UniProtKB=Q86VV8 Q86VV8 RTTN PTHR31691:SF1 ROTATIN ROTATIN cellular component assembly#GO:0022607;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;plasma membrane bounded cell projection organization#GO:0120036;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=11290|UniProtKB=Q12772 Q12772 SREBF2 PTHR46062:SF3 STEROL REGULATORY ELEMENT-BINDING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;macromolecule localization#GO:0033036;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;lipid localization#GO:0010876;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;lipid storage#GO:0019915;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=32947|UniProtKB=Q6ZRF8 Q6ZRF8 RNF207 PTHR22635:SF0 UNCHARACTERIZED RING FINGER PROTEIN 207 HUMAN|HGNC=4837|UniProtKB=P53701 P53701 HCCS PTHR12743:SF0 CYTOCHROME C1 HEME LYASE CYTOCHROME C-TYPE HEME LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;cytochrome complex assembly#GO:0017004;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 lyase#PC00144 HUMAN|HGNC=2349|UniProtKB=Q99941 Q99941 ATF6B PTHR46164:SF2 ATF6, ISOFORM C CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-6 BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;response to endoplasmic reticulum stress#GO:0034976;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;response to unfolded protein#GO:0006986;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 Apoptosis signaling pathway#P00006>ATF#P00302 HUMAN|HGNC=3667|UniProtKB=Q92914 Q92914 FGF11 PTHR11486:SF67 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 11 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=15281|UniProtKB=Q8NGL3 Q8NGL3 OR5D14 PTHR48018:SF65 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D14 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=21040|UniProtKB=Q9UMY1 Q9UMY1 NOL7 PTHR32337:SF2 NUCLEOLAR PROTEIN 7 NUCLEOLAR PROTEIN 7 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 HUMAN|HGNC=29292|UniProtKB=Q5VUJ6 Q5VUJ6 LRCH2 PTHR16083:SF11 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=26900|UniProtKB=Q2M329 Q2M329 CCDC96 PTHR15654:SF1 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 96 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=5130|UniProtKB=P31274 P31274 HOXC9 PTHR45970:SF1 AGAP004664-PA HOMEOBOX PROTEIN HOX-C9 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16108|UniProtKB=Q8TDL5 Q8TDL5 BPIFB1 PTHR47395:SF1 BPI FOLD-CONTAINING FAMILY B MEMBER 1 BPI FOLD-CONTAINING FAMILY B MEMBER 1 HUMAN|HGNC=31088|UniProtKB=Q5I7T1 Q5I7T1 ALG10B PTHR12989:SF12 ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10 DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE-RELATED transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=19037|UniProtKB=O15021 O15021 MAST4 PTHR24356:SF224 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE/THREONINE-PROTEIN KINASE 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=17442|UniProtKB=Q8WX39 Q8WX39 LCN9 PTHR11430:SF28 LIPOCALIN EPIDIDYMAL-SPECIFIC LIPOCALIN-9 binding#GO:0005488 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 HUMAN|HGNC=946|UniProtKB=Q96QZ7 Q96QZ7 MAGI1 PTHR10316:SF12 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=34345|UniProtKB=Q6PIY5 Q6PIY5 ARMH1 PTHR34258:SF1 ARMADILLO-LIKE HELICAL DOMAIN CONTAINING PROTEIN 1 ARMADILLO-LIKE HELICAL DOMAIN CONTAINING PROTEIN 1 HUMAN|HGNC=28979|UniProtKB=Q14687 Q14687 GSE1 PTHR17608:SF4 GENETIC SUPPRESSOR ELEMENT 1 GENETIC SUPPRESSOR ELEMENT 1 HUMAN|HGNC=9795|UniProtKB=Q92696 Q92696 RABGGTA PTHR11129:SF2 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein prenylation#GO:0018342;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 acyltransferase#PC00042 HUMAN|HGNC=25844|UniProtKB=Q9H898 Q9H898 ZMAT4 PTHR46144:SF3 ZINC FINGER PROTEIN 385B-LIKE ZINC FINGER MATRIN-TYPE PROTEIN 4 HUMAN|HGNC=18862|UniProtKB=Q9H252 Q9H252 KCNH6 PTHR10217:SF468 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 6 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=29221|UniProtKB=Q86X10 Q86X10 RALGAPB PTHR21344:SF1 UNCHARACTERIZED RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 HUMAN|HGNC=29668|UniProtKB=Q6FI13 Q6FI13 H2AC18 PTHR23430:SF42 HISTONE H2A HISTONE H2A TYPE 2-A heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=24738|UniProtKB=Q96MH7 Q96MH7 C5orf34 PTHR34531:SF1 ZGC:153352 ZGC:153352 HUMAN|HGNC=13652|UniProtKB=A6H8Y1 A6H8Y1 BDP1 PTHR22929:SF0 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B TRANSCRIPTION FACTOR TFIIIB COMPONENT B'' HOMOLOG general transcription factor#PC00259 HUMAN|HGNC=2232|UniProtKB=P35606 P35606 COPB2 PTHR19876:SF2 COATOMER COATOMER SUBUNIT BETA' endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;COPI vesicle coat#GO:0030126;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=19118|UniProtKB=Q8NFZ5 Q8NFZ5 TNIP2 PTHR31882:SF10 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 HUMAN|HGNC=7668|UniProtKB=Q15788 Q15788 NCOA1 PTHR10684:SF1 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;binding#GO:0005488;transcription coactivator activity#GO:0003713;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;nuclear receptor transcription coactivator activity#GO:0030374;molecular function regulator#GO:0098772;protein binding#GO:0005515;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;DNA-binding transcription factor binding#GO:0140297 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=28217|UniProtKB=Q969S6 Q969S6 TMEM203 PTHR13568:SF9 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 203 HUMAN|HGNC=2977|UniProtKB=O14717 O14717 TRDMT1 PTHR46098:SF1 TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE RNA processing factor#PC00147 HUMAN|HGNC=29371|UniProtKB=Q6GPH6 Q6GPH6 ITPRIPL1 PTHR10656:SF40 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN-LIKE 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=18016|UniProtKB=Q8WUM0 Q8WUM0 NUP133 PTHR13405:SF11 NUCLEAR PORE COMPLEX PROTEIN NUP133 NUCLEAR PORE COMPLEX PROTEIN NUP133 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;peptide transport#GO:0015833;mRNA transport#GO:0051028;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;organelle organization#GO:0006996;chromosome organization#GO:0051276;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170;protein-containing complex localization#GO:0031503 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=3576|UniProtKB=Q9Y5Q0 Q9Y5Q0 FADS3 PTHR19353:SF11 FATTY ACID DESATURASE 2 FATTY ACID DESATURASE 3 HUMAN|HGNC=1492|UniProtKB=Q9UHJ6 Q9UHJ6 SHPK PTHR10196:SF67 SUGAR KINASE SEDOHEPTULOKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 carbohydrate kinase#PC00065 HUMAN|HGNC=33763|UniProtKB=Q6UX34 Q6UX34 SNORC PTHR28453:SF1 PROTEIN SNORC PROTEIN SNORC HUMAN|HGNC=9284|UniProtKB=Q96QC0 Q96QC0 PPP1R10 PTHR46557:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10 phosphatase modulator#PC00184 HUMAN|HGNC=2054|UniProtKB=Q9NY25 Q9NY25 CLEC5A PTHR47536:SF1 C-TYPE LECTIN DOMAIN FAMILY 5 MEMBER A C-TYPE LECTIN DOMAIN FAMILY 5 MEMBER A HUMAN|HGNC=27441|UniProtKB=Q3KP22 Q3KP22 MAJIN PTHR35824:SF1 MEMBRANE-ANCHORED JUNCTION PROTEIN MAJIN MEMBRANE-ANCHORED JUNCTION PROTEIN cellular localization#GO:0051641;organelle localization#GO:0051640;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;chromosome segregation#GO:0007059;M phase#GO:0000279;chromosome organization involved in meiotic cell cycle#GO:0070192;establishment of localization#GO:0051234;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle phase#GO:0022403;establishment of organelle localization#GO:0051656;meiosis I#GO:0007127;meiosis I cell cycle phase#GO:0098764;nuclear chromosome segregation#GO:0098813;establishment of chromosome localization#GO:0051303;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;biological phase#GO:0044848;chromosome localization#GO:0050000 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;integral component of organelle membrane#GO:0031301;nuclear membrane#GO:0031965;non-membrane-bounded organelle#GO:0043228;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;chromosome#GO:0005694;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;chromosomal region#GO:0098687;envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;nuclear chromosome, telomeric region#GO:0000784;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular organelle lumen#GO:0070013;organelle inner membrane#GO:0019866;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;chromosome, telomeric region#GO:0000781;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;plasma membrane#GO:0005886 HUMAN|HGNC=4093|UniProtKB=Q05329 Q05329 GAD2 PTHR45677:SF11 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE 2 decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 HUMAN|HGNC=11153|UniProtKB=P14678 P14678 SNRPB PTHR10701:SF15 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEINS B AND B' cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Lsm2-8 complex#GO:0120115;U2-type prespliceosome#GO:0071004;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974 RNA splicing factor#PC00148 HUMAN|HGNC=4070|UniProtKB=Q9UBS5 Q9UBS5 GABBR1 PTHR10519:SF73 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 HUMAN|HGNC=49396|UniProtKB=P0DMB1 P0DMB1 PRR23D2 PTHR31813:SF3 PROLINE-RICH PROTEIN 23B PROLINE-RICH PROTEIN 23D1-RELATED HUMAN|HGNC=5890|UniProtKB=P01705 P01705 IGLV2-23 PTHR23267:SF407 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 2-14-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=2552|UniProtKB=Q13617 Q13617 CUL2 PTHR11932:SF131 CULLIN CULLIN-2 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=4664|UniProtKB=Q12789 Q12789 GTF3C1 PTHR15180:SF1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 general transcription factor#PC00259 HUMAN|HGNC=30499|UniProtKB=Q6NSJ2 Q6NSJ2 PHLDB3 PTHR12156:SF22 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 3 HUMAN|HGNC=14854|UniProtKB=Q8NH49 Q8NH49 OR4X1 PTHR48002:SF44 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4X1 transmembrane signal receptor#PC00197 HUMAN|HGNC=16511|UniProtKB=Q92599 Q92599 SEPTIN8 PTHR18884:SF54 SEPTIN SEPTIN-8 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cell division#GO:0051301;cellular localization#GO:0051641;membrane fission#GO:0090148;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 HUMAN|HGNC=9062|UniProtKB=Q9BRC7 Q9BRC7 PLCD4 PTHR10336:SF31 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-4 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 HUMAN|HGNC=20284|UniProtKB=O43166 O43166 SIPA1L1 PTHR15711:SF10 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 1 GTPase-activating protein#PC00257 HUMAN|HGNC=3535|UniProtKB=P00734 P00734 F2 PTHR24254:SF10 PROTHROMBIN PROTHROMBIN serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of wound healing#GO:0090303;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;platelet activation#GO:0030168;regulation of coagulation#GO:0050818;regulation of response to stress#GO:0080134;regulation of body fluid levels#GO:0050878;wound healing#GO:0042060;cellular process#GO:0009987;hemostasis#GO:0007599;coagulation#GO:0050817;regulation of response to wounding#GO:1903034;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of wound healing#GO:0061041;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>Prothrombin#P00416;Blood coagulation#P00011>Thrombin#P00414 HUMAN|HGNC=13973|UniProtKB=Q96KW2 Q96KW2 POM121L2 PTHR23193:SF20 NUCLEAR PORE COMPLEX PROTEIN NUP POM121-LIKE PROTEIN 12-RELATED signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=28562|UniProtKB=Q8N309 Q8N309 LRRC43 PTHR45973:SF6 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 43 phosphatase modulator#PC00184 HUMAN|HGNC=11406|UniProtKB=Q13188 Q13188 STK3 PTHR48015:SF23 SERINE/THREONINE-PROTEIN KINASE TAO SERINE/THREONINE-PROTEIN KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=5476|UniProtKB=Q16270 Q16270 IGFBP7 PTHR14186:SF15 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=3054|UniProtKB=Q9NZW4 Q9NZW4 DSPP PTHR47819:SF1 DENTIN SIALOPHOSPHOPROTEIN DENTIN SIALOPHOSPHOPROTEIN HUMAN|HGNC=29235|UniProtKB=Q9ULE4 Q9ULE4 FAM184B PTHR18870:SF8 PROTEIN TAG-278-RELATED PROTEIN FAM184B HUMAN|HGNC=1405|UniProtKB=Q06432 Q06432 CACNG1 PTHR15025:SF1 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;channel activity#GO:0015267;transporter activity#GO:0005215 regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;calcium ion transmembrane transport#GO:0070588;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;localization#GO:0051179;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;divalent inorganic cation transport#GO:0072511;regulation of ion transport#GO:0043269 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;sarcolemma#GO:0042383;voltage-gated calcium channel complex#GO:0005891;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=21208|UniProtKB=Q9H7D7 Q9H7D7 WDR26 PTHR22838:SF0 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 26 HUMAN|HGNC=14955|UniProtKB=Q9NPC7 Q9NPC7 MYNN PTHR23226:SF170 ZINC FINGER AND SCAN DOMAIN-CONTAINING MYONEURIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25686|UniProtKB=Q9HAB8 Q9HAB8 PPCS PTHR12290:SF2 CORNICHON-RELATED PHOSPHOPANTOTHENATE--CYSTEINE LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882 HUMAN|HGNC=31668|UniProtKB=Q2TAP0 Q2TAP0 GOLGA7B PTHR13254:SF2 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 GOLGIN SUBFAMILY A MEMBER 7B transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;organic substance biosynthetic process#GO:1901576;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lipoprotein metabolic process#GO:0042157 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=3272|UniProtKB=Q13347 Q13347 EIF3I PTHR19877:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=25986|UniProtKB=Q6P3X3 Q6P3X3 TTC27 PTHR16193:SF0 UNCHARACTERIZED TETRATRICOPEPTIDE REPEAT PROTEIN 27 HUMAN|HGNC=17474|UniProtKB=Q96AP7 Q96AP7 ESAM PTHR44549:SF1 ENDOTHELIAL CELL-SELECTIVE ADHESION MOLECULE ENDOTHELIAL CELL-SELECTIVE ADHESION MOLECULE HUMAN|HGNC=25234|UniProtKB=Q9BUV0 Q9BUV0 RSRP1 PTHR47622:SF1 ARGININE/SERINE-RICH PROTEIN 1 ARGININE/SERINE-RICH PROTEIN 1 HUMAN|HGNC=5929|UniProtKB=P04211 P04211 IGLV7-43 PTHR23267:SF335 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 7-43 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=10583|UniProtKB=Q9UI33 Q9UI33 SCN11A PTHR10037:SF210 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN TYPE 11 SUBUNIT ALPHA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sodium channel activity#GO:0005272;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;action potential#GO:0001508;nervous system process#GO:0050877;cell communication#GO:0007154;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;sodium ion transport#GO:0006814;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267;sodium ion transmembrane transport#GO:0035725 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=1120|UniProtKB=Q9H0C5 Q9H0C5 BTBD1 PTHR45774:SF1 BTB/POZ DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN 1 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cellular process#GO:0009987;nervous system development#GO:0007399 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=5525|UniProtKB=P01857 P01857 IGHG1 PTHR23266:SF350 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=28704|UniProtKB=Q7Z2Z1 Q7Z2Z1 TICRR PTHR21556:SF2 UNCHARACTERIZED TRESLIN chromatin binding#GO:0003682;binding#GO:0005488 regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;mitotic DNA integrity checkpoint#GO:0044774;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication initiation#GO:0006270;cell cycle G2/M phase transition#GO:0044839;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;mitotic cell cycle phase transition#GO:0044772;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;mitotic DNA replication checkpoint#GO:0033314;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;G2 DNA damage checkpoint#GO:0031572;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;mitotic DNA damage checkpoint#GO:0044773;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;negative regulation of mitotic cell cycle#GO:0045930;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA replication checkpoint#GO:0000076;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;mitotic G2 DNA damage checkpoint#GO:0007095;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;DNA replication#GO:0006260;regulation of mitotic cell cycle#GO:0007346;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12734|UniProtKB=Q9UPY6 Q9UPY6 WASF3 PTHR12902:SF7 WASP-1 WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER 3 protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cell leading edge#GO:0031252;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lamellipodium#GO:0030027;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cell projection#GO:0042995;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 HUMAN|HGNC=14383|UniProtKB=Q8N9R6 Q8N9R6 CDRT4 PTHR37885:SF1 CMT1A DUPLICATED REGION TRANSCRIPT 4 PROTEIN CMT1A DUPLICATED REGION TRANSCRIPT 4 PROTEIN HUMAN|HGNC=29034|UniProtKB=O43313 O43313 ATMIN PTHR46664:SF2 ATM INTERACTOR ATM INTERACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=20804|UniProtKB=Q96B54 Q96B54 ZNF428 PTHR36862:SF1 ZINC FINGER PROTEIN 428 ZINC FINGER PROTEIN 428 HUMAN|HGNC=14726|UniProtKB=Q8NGD4 Q8NGD4 OR4K1 PTHR48002:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K1 transmembrane signal receptor#PC00197 HUMAN|HGNC=8043|UniProtKB=Q02818 Q02818 NUCB1 PTHR19237:SF21 NUCLEOBINDIN NUCLEOBINDIN-1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 calmodulin-related#PC00061 HUMAN|HGNC=31704|UniProtKB=Q6HA08 Q6HA08 ASTL PTHR10127:SF855 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING ASTACIN-LIKE METALLOENDOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153 HUMAN|HGNC=10736|UniProtKB=Q13591 Q13591 SEMA5A PTHR11036:SF78 SEMAPHORIN SEMAPHORIN-5A receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=8822|UniProtKB=Q15121 Q15121 PEA15 PTHR48169:SF1 DED DOMAIN-CONTAINING PROTEIN ASTROCYTIC PHOSPHOPROTEIN PEA-15 Gonadotropin-releasing hormone receptor pathway#P06664>PEA-15#P06853 HUMAN|HGNC=27396|UniProtKB=Q68DD2 Q68DD2 PLA2G4F PTHR10728:SF22 CYTOSOLIC PHOSPHOLIPASE A2 CYTOSOLIC PHOSPHOLIPASE A2 ZETA hydrolase activity, acting on ester bonds#GO:0016788;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;phospholipid binding#GO:0005543;carboxylic ester hydrolase activity#GO:0052689;cation binding#GO:0043169;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;hydrolase activity#GO:0016787;calcium ion binding#GO:0005509;lipid binding#GO:0008289;phospholipase activity#GO:0004620;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phospholipase#PC00186 HUMAN|HGNC=17756|UniProtKB=Q9HAV5 Q9HAV5 EDA2R PTHR12120:SF8 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 27 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=9363|UniProtKB=Q9Y2Y8 Q9Y2Y8 PRG3 PTHR10068:SF8 BONE MARROW PROTEOGLYCAN PROTEOGLYCAN 3 extracellular matrix structural protein#PC00103 HUMAN|HGNC=16850|UniProtKB=Q6PD62 Q6PD62 CTR9 PTHR14027:SF2 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;histone methylation#GO:0016571;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein alkylation#GO:0008213;protein methylation#GO:0006479;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of chromatin organization#GO:1902275;histone H3-K4 methylation#GO:0051568;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of histone modification#GO:0031056;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;histone lysine methylation#GO:0034968;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;methylation#GO:0032259;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=17148|UniProtKB=Q53HV7 Q53HV7 SMUG1 PTHR13235:SF2 SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA glycosylase#PC00010 HUMAN|HGNC=28292|UniProtKB=Q8N6I1 Q8N6I1 EID2 PTHR15556:SF3 EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 2-RELATED EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 2 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3092|UniProtKB=Q9Y463 Q9Y463 DYRK1B PTHR24058:SF12 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;molecular function regulator#GO:0098772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;peptidyl-threonine phosphorylation#GO:0018107;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19368|UniProtKB=Q4G0P3 Q4G0P3 HYDIN PTHR23053:SF0 DLEC1 DELETED IN LUNG AND ESOPHAGEAL CANCER 1 HYDROCEPHALUS-INDUCING PROTEIN HOMOLOG HUMAN|HGNC=7965|UniProtKB=P55055 P55055 NR1H2 PTHR24082:SF316 NUCLEAR HORMONE RECEPTOR OXYSTEROLS RECEPTOR LXR-BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=16495|UniProtKB=Q9NRY6 Q9NRY6 PLSCR3 PTHR23248:SF37 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE 3 phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;plasma membrane organization#GO:0007009;ion transport#GO:0006811;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=10315|UniProtKB=P35268 P35268 RPL22 PTHR10064:SF2 60S RIBOSOMAL PROTEIN L22 60S RIBOSOMAL PROTEIN L22 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribosomal protein#PC00202 HUMAN|HGNC=20908|UniProtKB=Q86YF9 Q86YF9 DZIP1 PTHR21502:SF5 ZINC FINGER PROTEIN DZIP1 ZINC FINGER PROTEIN DZIP1 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=6143|UniProtKB=Q13683 Q13683 ITGA7 PTHR23220:SF90 INTEGRIN ALPHA INTEGRIN ALPHA-7 integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=17482|UniProtKB=Q9UNW8 Q9UNW8 GPR132 PTHR24234:SF7 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR G-PROTEIN COUPLED RECEPTOR 132-RELATED negative regulation of biological process#GO:0048519;mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;G1/S transition of mitotic cell cycle#GO:0000082;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;negative regulation of cellular process#GO:0048523;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839 G-protein coupled receptor#PC00021 HUMAN|HGNC=9544|UniProtKB=Q99436 Q99436 PSMB7 PTHR11599:SF42 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-7 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=3825|UniProtKB=O14772 O14772 FPGT PTHR15045:SF1 FUCOSE-1-PHOSPHATE GUANYLYLTRANSFERASE FUCOSE-1-PHOSPHATE GUANYLYLTRANSFERASE transferase#PC00220 HUMAN|HGNC=1338|UniProtKB=P21730 P21730 C5AR1 PTHR24225:SF29 CHEMOTACTIC RECEPTOR C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR 1 complement binding#GO:0001848;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;immune response-regulating signaling pathway#GO:0002764;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;activation of immune response#GO:0002253;divalent inorganic cation homeostasis#GO:0072507;regulation of lipase activity#GO:0060191;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;immune response-activating signal transduction#GO:0002757;activation of phospholipase C activity#GO:0007202;regulation of immune system process#GO:0002682;regulation of hydrolase activity#GO:0051336;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;cellular cation homeostasis#GO:0030003;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;regulation of immune response#GO:0050776;positive regulation of phospholipase activity#GO:0010518;positive regulation of immune system process#GO:0002684;homeostatic process#GO:0042592;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;metal ion homeostasis#GO:0055065 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=5213|UniProtKB=P51659 P51659 HSD17B4 PTHR13078:SF56 PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2 HUMAN|HGNC=15967|UniProtKB=P81534 P81534 DEFB103A PTHR20515:SF0 BETA-DEFENSIN BETA-DEFENSIN 103 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;interspecies interaction between organisms#GO:0044419;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;localization#GO:0051179;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;response to chemical#GO:0042221;defense response to other organism#GO:0098542;response to other organism#GO:0051707;movement of cell or subcellular component#GO:0006928;defense response#GO:0006952;cell migration#GO:0016477;locomotion#GO:0040011;chemotaxis#GO:0006935;taxis#GO:0042330 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=15878|UniProtKB=Q9NQ75 Q9NQ75 CASS4 PTHR10654:SF19 CAS SCAFFOLDING PROTEIN CAS SCAFFOLDING PROTEIN FAMILY MEMBER 4 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;actin cytoskeleton reorganization#GO:0031532;enzyme linked receptor protein signaling pathway#GO:0007167;localization of cell#GO:0051674;cell motility#GO:0048870;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 HUMAN|HGNC=1072|UniProtKB=P22003 P22003 BMP5 PTHR11848:SF139 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 5 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=30416|UniProtKB=O14796 O14796 SH2D1B PTHR46051:SF5 SH2 DOMAIN-CONTAINING PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 1B HUMAN|HGNC=16731|UniProtKB=Q969P5 Q969P5 FBXO32 PTHR13123:SF6 LD30288P F-BOX ONLY PROTEIN 32 HUMAN|HGNC=10449|UniProtKB=Q92766 Q92766 RREB1 PTHR46451:SF1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=5724|UniProtKB=Q06330 Q06330 RBPJ PTHR10665:SF3 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS cis-regulatory region sequence-specific DNA binding#GO:0000987;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 Notch signaling pathway#P00045>Su(H)#P01101;Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Angiogenesis#P00005>CSL#P00233 HUMAN|HGNC=12339|UniProtKB=O94759 O94759 TRPM2 PTHR13800:SF2 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 2 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;localization#GO:0051179;divalent metal ion transport#GO:0070838;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=31921|UniProtKB=Q3KQZ1 Q3KQZ1 SLC25A35 PTHR45928:SF2 RE38146P SOLUTE CARRIER FAMILY 25 MEMBER 35 HUMAN|HGNC=12666|UniProtKB=P55072 P55072 VCP PTHR23077:SF69 AAA-FAMILY ATPASE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 cellular localization#GO:0051641;macroautophagy#GO:0016236;nuclear division#GO:0000280;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;modification-dependent macromolecule catabolic process#GO:0043632;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein-containing complex disassembly#GO:0032984;response to endoplasmic reticulum stress#GO:0034976;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;peptide transport#GO:0015833;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;protein transport#GO:0015031;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;autophagy#GO:0006914;cellular response to misfolded protein#GO:0071218;mitotic spindle organization#GO:0007052;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound catabolic process#GO:1901565;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;amide transport#GO:0042886;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;cellular component disassembly#GO:0022411;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;organic substance catabolic process#GO:1901575;autophagosome maturation#GO:0097352;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;organelle disassembly#GO:1903008;localization#GO:0051179;response to stimulus#GO:0050896;microtubule-based process#GO:0007017;response to chemical#GO:0042221;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;response to topologically incorrect protein#GO:0035966;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;ubiquitin-dependent ERAD pathway#GO:0030433;organelle fission#GO:0048285;intracellular protein transport#GO:0006886;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=1587|UniProtKB=O95273 O95273 CCNDBP1 PTHR15492:SF4 CYCLIN D1-BINDING PROTEIN 1 CYCLIN-D1-BINDING PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=26958|UniProtKB=Q8NDA8 Q8NDA8 MROH1 PTHR23120:SF44 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 1 HUMAN|HGNC=7396|UniProtKB=A1L3X4 A1L3X4 MT1DP PTHR23299:SF48 METALLOTHIONEIN METALLOTHIONEIN-1E-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;transition metal ion homeostasis#GO:0055076;response to metal ion#GO:0010038;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;response to toxic substance#GO:0009636;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=8290|UniProtKB=Q8NGF8 Q8NGF8 OR4B1 PTHR48002:SF2 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4B1 transmembrane signal receptor#PC00197 HUMAN|HGNC=19004|UniProtKB=Q6UXS9 Q6UXS9 CASP12 PTHR10454:SF134 CASPASE INACTIVE CASPASE-12 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=16650|UniProtKB=Q9H9J2 Q9H9J2 MRPL44 PTHR11207:SF5 RIBONUCLEASE III 39S RIBOSOMAL PROTEIN L44, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;heterocyclic compound binding#GO:1901363;double-stranded RNA binding#GO:0003725 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression#GO:0010468;regulation of gene expression, epigenetic#GO:0040029;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;gene silencing by miRNA#GO:0035195;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA interference#GO:0016246;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;gene silencing by RNA#GO:0031047;cellular process#GO:0009987;primary metabolic process#GO:0044238;production of miRNAs involved in gene silencing by miRNA#GO:0035196;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;posttranscriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 endoribonuclease#PC00094 HUMAN|HGNC=10388|UniProtKB=P62841 P62841 RPS15 PTHR11880:SF28 RIBOSOMAL PROTEIN S19P FAMILY MEMBER 40S RIBOSOMAL PROTEIN S15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;ribonucleoprotein complex subunit organization#GO:0071826;ribonucleoprotein complex assembly#GO:0022618;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;ribosome biogenesis#GO:0042254;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=29164|UniProtKB=Q9Y2I9 Q9Y2I9 TBC1D30 PTHR22957:SF601 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 30 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=14304|UniProtKB=Q8IWX7 Q8IWX7 UNC45B PTHR45994:SF2 FI21225P1 PROTEIN UNC-45 HOMOLOG B heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488;Hsp90 protein binding#GO:0051879 chaperone-mediated protein folding#GO:0061077;cellular process#GO:0009987;protein folding#GO:0006457 HUMAN|HGNC=18757|UniProtKB=O94955 O94955 RHOBTB3 PTHR24072:SF139 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 3 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;membrane organization#GO:0061024;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;phagocytosis#GO:0006909;regulation of organelle organization#GO:0033043;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;apoptotic cell clearance#GO:0043277;locomotion#GO:0040011;taxis#GO:0042330;establishment or maintenance of cell polarity#GO:0007163;neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;transport#GO:0006810;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;supramolecular fiber organization#GO:0097435;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;neuron differentiation#GO:0030182;vesicle organization#GO:0016050;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;vesicle budding from membrane#GO:0006900;regulation of developmental process#GO:0050793;motor neuron axon guidance#GO:0008045;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=7809|UniProtKB=P08138 P08138 NGFR PTHR46605:SF3 TUMOR NECROSIS FACTOR RECEPTOR TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16 growth factor binding#GO:0019838;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=26386|UniProtKB=Q8N4S7 Q8N4S7 PAQR4 PTHR20855:SF115 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 4 G-protein coupled receptor#PC00021 HUMAN|HGNC=20218|UniProtKB=Q8N6I4 Q8N6I4 TMEM251 PTHR31925:SF1 TRANSMEMBRANE PROTEIN 251 TRANSMEMBRANE PROTEIN 251 HUMAN|HGNC=24501|UniProtKB=Q58EX7 Q58EX7 PLEKHG4 PTHR45845:SF4 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED PURATROPHIN-1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=3018|UniProtKB=P40879 P40879 SLC26A3 PTHR11814:SF19 SULFATE TRANSPORTER CHLORIDE ANION EXCHANGER inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;inorganic anion transmembrane transporter activity#GO:0015103;active ion transmembrane transporter activity#GO:0022853 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=28338|UniProtKB=Q6ZUT9 Q6ZUT9 DENND5B PTHR46070:SF3 PINSTRIPE, ISOFORM A DENN DOMAIN-CONTAINING PROTEIN 5B HUMAN|HGNC=26936|UniProtKB=Q05D32 Q05D32 CTDSPL2 PTHR12210:SF173 NUCLEAR LIM INTERACTOR-INTERACTING FACTOR-RELATED CTD SMALL PHOSPHATASE-LIKE PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 HUMAN|HGNC=7422|UniProtKB=P00414 P00414 MT-CO3 PTHR11403:SF7 CYTOCHROME C OXIDASE SUBUNIT III CYTOCHROME C OXIDASE SUBUNIT 3 transmembrane transporter activity#GO:0022857;electron transfer activity#GO:0009055;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;active transmembrane transporter activity#GO:0022804 cellular respiration#GO:0045333;aerobic respiration#GO:0009060;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 oxidase#PC00175 HUMAN|HGNC=10351|UniProtKB=Q92901 Q92901 RPL3L PTHR11363:SF7 60S RIBOSOMAL PROTEIN L3-RELATED 60S RIBOSOMAL PROTEIN L3-LIKE structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=3245|UniProtKB=Q9H223 Q9H223 EHD4 PTHR11216:SF57 EH DOMAIN EH DOMAIN-CONTAINING PROTEIN 4 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 microtubule-based protein transport#GO:0099118;endosomal transport#GO:0016197;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;endocytic recycling#GO:0032456;membrane invagination#GO:0010324;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;protein localization to plasma membrane#GO:0072659;vesicle localization#GO:0051648;protein localization to membrane#GO:0072657;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;protein localization to cell periphery#GO:1990778;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;perinuclear region of cytoplasm#GO:0048471;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=8465|UniProtKB=Q8NGA0 Q8NGA0 OR7G1 PTHR48001:SF67 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7G1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=12643|UniProtKB=P63027 P63027 VAMP2 PTHR45701:SF5 SYNAPTOBREVIN FAMILY MEMBER VESICLE-ASSOCIATED MEMBRANE PROTEIN 2 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;syntaxin-1 binding#GO:0017075;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;organelle fusion#GO:0048284;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular#GO:0005622;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Synaptic vesicle trafficking#P05734>Synaptobrevin#P05779;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 HUMAN|HGNC=25067|UniProtKB=Q96CB8 Q96CB8 INTS12 PTHR13415:SF2 NUCLEAR FACTOR-RELATED INTEGRATOR COMPLEX SUBUNIT 12 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 HUMAN|HGNC=1479|UniProtKB=P17655 P17655 CAPN2 PTHR10183:SF268 CALPAIN CALPAIN-2 CATALYTIC SUBUNIT cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=5182|UniProtKB=P35367 P35367 HRH1 PTHR24247:SF223 5-HYDROXYTRYPTAMINE RECEPTOR HISTAMINE H1 RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Histamine H1 receptor mediated signaling pathway#P04385>H1#P04485 HUMAN|HGNC=12964|UniProtKB=Q9Y473 Q9Y473 ZNF175 PTHR24377:SF37 IP01015P-RELATED ZINC FINGER PROTEIN 175 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4975|UniProtKB=Q95460 Q95460 MR1 PTHR16675:SF242 MHC CLASS I-RELATED MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-RELATED GENE PROTEIN response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=13851|UniProtKB=Q6R2W3 Q6R2W3 ZBED9 PTHR45935:SF17 PROTEIN ZBED8-RELATED SCAN DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=10922|UniProtKB=P53985 P53985 SLC16A1 PTHR11360:SF24 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=29514|UniProtKB=Q6ZMI3 Q6ZMI3 GLDN PTHR23192:SF5 OLFACTOMEDIN-RELATED GLIOMEDIN structural protein#PC00211 HUMAN|HGNC=7645|UniProtKB=P18440 P18440 NAT1 PTHR11786:SF8 N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE ARYLAMINE N-ACETYLTRANSFERASE 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 HUMAN|HGNC=24054|UniProtKB=Q8NG31 Q8NG31 KNL1 PTHR16520:SF3 KINETOCHORE SCAFFOLD 1 KINETOCHORE SCAFFOLD 1 localization#GO:0051179;nuclear chromosome segregation#GO:0098813;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;protein localization to kinetochore#GO:0034501;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;cell cycle#GO:0007049;attachment of spindle microtubules to kinetochore#GO:0008608;protein localization to organelle#GO:0033365;cellular process#GO:0009987;chromosome segregation#GO:0007059;protein localization#GO:0008104 supramolecular complex#GO:0099080;kinetochore#GO:0000776;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;condensed chromosome, centromeric region#GO:0000779;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687 HUMAN|HGNC=6242|UniProtKB=Q9Y6J6 Q9Y6J6 KCNE2 PTHR15282:SF8 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;protein binding#GO:0005515;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 blood circulation#GO:0008015;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of metal ion transport#GO:0010959;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;action potential#GO:0001508;regulation of localization#GO:0032879;regulation of system process#GO:0044057;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;actin-mediated cell contraction#GO:0070252;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;actin filament-based process#GO:0030029;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;monovalent inorganic cation transport#GO:0015672;regulation of multicellular organismal process#GO:0051239;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of heart contraction#GO:0008016;ion transport#GO:0006811;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;regulation of membrane potential#GO:0042391;negative regulation of transport#GO:0051051;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;striated muscle contraction#GO:0006941;circulatory system process#GO:0003013;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;muscle system process#GO:0003012;export from cell#GO:0140352;heart process#GO:0003015;muscle contraction#GO:0006936;negative regulation of molecular function#GO:0044092 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=17972|UniProtKB=Q9NPD7 Q9NPD7 NRN1 PTHR15902:SF1 NEURITIN-RELATED NEURITIN HUMAN|HGNC=31999|UniProtKB=A0A087WUL8 A0A087WUL8 NBPF19 PTHR14199:SF35 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 10-RELATED HUMAN|HGNC=8826|UniProtKB=Q9GZU2 Q9GZU2 PEG3 PTHR24381:SF293 ZINC FINGER PROTEIN PATERNALLY-EXPRESSED GENE 3 PROTEIN DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25659|UniProtKB=A0A1B0GTU1 A0A1B0GTU1 ZC3H11B PTHR15725:SF13 ZN-FINGER, C-X8-C-X5-C-X3-H TYPE-CONTAINING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 11B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=26940|UniProtKB=Q9UI30 Q9UI30 TRMT112 PTHR12773:SF2 UPF0315 PROTEIN-RELATED MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;tRNA processing#GO:0008033;RNA processing#GO:0006396;protein modification process#GO:0036211;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;protein alkylation#GO:0008213;ncRNA metabolic process#GO:0034660;protein methylation#GO:0006479;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 HUMAN|HGNC=12981|UniProtKB=P17023 P17023 ZNF19 PTHR24381:SF59 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 19 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26912|UniProtKB=Q8NBT3 Q8NBT3 TMEM145 PTHR23252:SF24 INTIMAL THICKNESS RECEPTOR-RELATED TRANSMEMBRANE PROTEIN 145 HUMAN|HGNC=2593|UniProtKB=P05093 P05093 CYP17A1 PTHR24289:SF1 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE HUMAN|HGNC=12005|UniProtKB=P55327 P55327 TPD52 PTHR19307:SF12 TUMOR PROTEIN D52 TUMOR PROTEIN D52 HUMAN|HGNC=6338|UniProtKB=P43629 P43629 KIR3DL1 PTHR11738:SF166 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL1-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=20240|UniProtKB=Q8NAU1 Q8NAU1 FNDC5 PTHR14470:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 5 HUMAN|HGNC=4602|UniProtKB=P09341 P09341 CXCL1 PTHR10179:SF69 CXC CHEMOKINE GROWTH-REGULATED ALPHA PROTEIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 CCKR signaling map#P06959>CXCL1#G07268;CCKR signaling map#P06959>CXCL1#G06975 HUMAN|HGNC=6063|UniProtKB=Q9H160 Q9H160 ING2 PTHR10333:SF37 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 2 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=9439|UniProtKB=Q13217 Q13217 DNAJC3 PTHR44140:SF3 LD25575P DNAJ HOMOLOG SUBFAMILY C MEMBER 3 protein binding#GO:0005515;binding#GO:0005488;chaperone binding#GO:0051087 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=22935|UniProtKB=Q92797 Q92797 SYMPK PTHR15245:SF20 SYMPLEKIN-RELATED SYMPLEKIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 HUMAN|HGNC=3623|UniProtKB=O00602 O00602 FCN1 PTHR19143:SF377 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-1 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=30084|UniProtKB=Q9UHQ7 Q9UHQ7 TCEAL9 PTHR14754:SF6 TRANSCRIPTION ELONGATION FACTOR A TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 9 general transcription factor#PC00259 HUMAN|HGNC=13933|UniProtKB=Q5SQ64 Q5SQ64 LY6G6F PTHR32286:SF10 LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6F LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6F HUMAN|HGNC=33277|UniProtKB=P0C2L3 P0C2L3 FAM163B PTHR31396:SF2 PROTEIN FAM163B MEMBER PROTEIN FAM163B HUMAN|HGNC=25020|UniProtKB=Q7L1V2 Q7L1V2 MON1B PTHR13027:SF13 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG B HUMAN|HGNC=25303|UniProtKB=Q6NSX1 Q6NSX1 CCDC70 PTHR21533:SF22 LEUCINE-RICH PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 70 HUMAN|HGNC=29302|UniProtKB=Q8TCG1 Q8TCG1 CIP2A PTHR23161:SF2 PROTEIN CIP2A PROTEIN CIP2A HUMAN|HGNC=11546|UniProtKB=Q15543 Q15543 TAF13 PTHR11380:SF5 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 general transcription factor#PC00259 HUMAN|HGNC=32291|UniProtKB=Q6ZNC4 Q6ZNC4 ZNF704 PTHR13006:SF7 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 ZINC FINGER PROTEIN 704 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=18008|UniProtKB=Q6DKJ4 Q6DKJ4 NXN PTHR46472:SF1 NUCLEOREDOXIN NUCLEOREDOXIN oxidoreductase#PC00176 HUMAN|HGNC=17030|UniProtKB=Q9HCN4 Q9HCN4 GPN1 PTHR21231:SF8 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 1 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 small GTPase#PC00208 HUMAN|HGNC=18315|UniProtKB=P52198 P52198 RND2 PTHR24072:SF21 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHON GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948 HUMAN|HGNC=26079|UniProtKB=Q5VZ89 Q5VZ89 DENND4C PTHR12296:SF17 C-MYC PROMOTER BINDING PROTEIN DENN DOMAIN-CONTAINING PROTEIN 4C Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;regulation of Ras protein signal transduction#GO:0046578;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=29061|UniProtKB=O60279 O60279 SUSD5 PTHR32493:SF0 SUSHI DOMAIN-CONTAINING PROTEIN 5 SUSHI DOMAIN-CONTAINING PROTEIN 5 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;Notch signaling pathway#GO:0007219 HUMAN|HGNC=20239|UniProtKB=Q9H6D8 Q9H6D8 FNDC4 PTHR14470:SF2 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=88|UniProtKB=P28330 P28330 ACADL PTHR48083:SF20 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;acyl-CoA dehydrogenase activity#GO:0003995;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 dehydrogenase#PC00092 HUMAN|HGNC=4527|UniProtKB=Q9P296 Q9P296 C5AR2 PTHR24225:SF1 CHEMOTACTIC RECEPTOR C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR 2 complement binding#GO:0001848;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;immune response-regulating signaling pathway#GO:0002764;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;activation of immune response#GO:0002253;divalent inorganic cation homeostasis#GO:0072507;regulation of lipase activity#GO:0060191;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;immune response-activating signal transduction#GO:0002757;activation of phospholipase C activity#GO:0007202;regulation of immune system process#GO:0002682;regulation of hydrolase activity#GO:0051336;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;cellular cation homeostasis#GO:0030003;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;regulation of immune response#GO:0050776;positive regulation of phospholipase activity#GO:0010518;positive regulation of immune system process#GO:0002684;homeostatic process#GO:0042592;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;metal ion homeostasis#GO:0055065 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=15153|UniProtKB=Q8NH70 Q8NH70 OR4A16 PTHR48002:SF159 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4A16 transmembrane signal receptor#PC00197 HUMAN|HGNC=20907|UniProtKB=Q96JC9 Q96JC9 EAF1 PTHR15970:SF8 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR 1 HUMAN|HGNC=8521|UniProtKB=P32242 P32242 OTX1 PTHR45793:SF9 HOMEOBOX PROTEIN HOMEOBOX PROTEIN OTX1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>OTX#P06818 HUMAN|HGNC=14026|UniProtKB=Q96PZ7 Q96PZ7 CSMD1 PTHR45656:SF3 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=21749|UniProtKB=Q7L5N1 Q7L5N1 COPS6 PTHR10540:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 6 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;COP9 signalosome#GO:0008180;intracellular organelle#GO:0043229 translation initiation factor#PC00224 HUMAN|HGNC=15130|UniProtKB=Q9H209 Q9H209 OR10A4 PTHR26453:SF9 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A4 transmembrane signal receptor#PC00197 HUMAN|HGNC=18398|UniProtKB=Q9H4L7 Q9H4L7 SMARCAD1 PTHR10799:SF964 SNF2/RAD54 HELICASE FAMILY SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A CONTAINING DEAD/H BOX 1 pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;ATP-dependent chromatin remodeling#GO:0043044;chromatin organization#GO:0006325;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA helicase#PC00011 HUMAN|HGNC=10825|UniProtKB=P78314 P78314 SH3BP2 PTHR15126:SF4 SH3-BINDING SH3 DOMAIN-BINDING PROTEIN 2 HUMAN|HGNC=13024|UniProtKB=Q9UIE0 Q9UIE0 ZNF230 PTHR24377:SF709 IP01015P-RELATED ZINC FINGER PROTEIN 230 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8896|UniProtKB=P00558 P00558 PGK1 PTHR11406:SF14 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE 1 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;small molecule binding#GO:0036094;organic cyclic compound binding#GO:0097159;binding#GO:0005488;catalytic activity#GO:0003824;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524;kinase activity#GO:0016301 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside diphosphate metabolic process#GO:0009135;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;positive regulation of cellular metabolic process#GO:0031325;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ATP generation from ADP#GO:0006757;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;oxidation-reduction process#GO:0055114;purine-containing compound metabolic process#GO:0072521;positive regulation of biological process#GO:0048518;ribonucleoside diphosphate metabolic process#GO:0009185;organic substance metabolic process#GO:0071704;purine nucleotide metabolic process#GO:0006163;purine ribonucleoside diphosphate metabolic process#GO:0009179;purine nucleoside triphosphate biosynthetic process#GO:0009145;oxoacid metabolic process#GO:0043436;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;nucleotide phosphorylation#GO:0046939;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;nucleoside diphosphate phosphorylation#GO:0006165;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;organic acid metabolic process#GO:0006082;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;positive regulation of phosphate metabolic process#GO:0045937;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;glycolytic process#GO:0006096;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;regulation of phosphate metabolic process#GO:0019220;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;cation transport#GO:0006812;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;heterocycle metabolic process#GO:0046483;positive regulation of phosphorylation#GO:0042327;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ADP metabolic process#GO:0046031;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;glucose metabolic process#GO:0006006;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;biological regulation#GO:0065007;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 HUMAN|HGNC=4574|UniProtKB=P48058 P48058 GRIA4 PTHR18966:SF100 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 4 amino acid binding#GO:0016597;cation channel activity#GO:0005261;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;glutamate binding#GO:0016595;ligand-gated channel activity#GO:0022834 membrane protein complex#GO:0098796;synapse#GO:0045202;somatodendritic compartment#GO:0036477;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;cell periphery#GO:0071944;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;postsynapse#GO:0098794;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu4#P01015;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019 HUMAN|HGNC=19158|UniProtKB=Q9H8X9 Q9H8X9 ZDHHC11 PTHR22883:SF22 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC11-RELATED transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=27912|UniProtKB=Q6ZMM2 Q6ZMM2 ADAMTSL5 PTHR13723:SF173 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 5 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=16663|UniProtKB=Q6MZZ7 Q6MZZ7 CAPN13 PTHR10183:SF333 CALPAIN CALPAIN-13 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=9437|UniProtKB=P19525 P19525 EIF2AK2 PTHR11042:SF163 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED INTERFERON-INDUCED, DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>PKR#P00293 HUMAN|HGNC=8114|UniProtKB=Q5BJF6 Q5BJF6 ODF2 PTHR23162:SF8 OUTER DENSE FIBER OF SPERM TAILS 2 OUTER DENSE FIBER PROTEIN 2 HUMAN|HGNC=1536|UniProtKB=O43439 O43439 CBFA2T2 PTHR10379:SF13 MTG8 ETO EIGHT TWENTY ONE PROTEIN PROTEIN CBFA2T2 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=14620|UniProtKB=Q9UGI8 Q9UGI8 TES PTHR24211:SF1 LIM DOMAIN-CONTAINING PROTEIN TESTIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=30967|UniProtKB=Q9BU70 Q9BU70 TRMO PTHR12818:SF0 UNCHARACTERIZED TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE HUMAN|HGNC=35645|UniProtKB=A6NKH3 A6NKH3 RPL37AP8 PTHR48188:SF2 60S RIBOSOMAL PROTEIN L43 60S RIBOSOMAL PROTEIN L37A-LIKE PROTEIN-RELATED ribosomal protein#PC00202 HUMAN|HGNC=29151|UniProtKB=Q9Y2E6 Q9Y2E6 DTX4 PTHR12622:SF5 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX4 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=20150|UniProtKB=P59190 P59190 RAB15 PTHR47980:SF4 LD44762P RAS-RELATED PROTEIN RAB-15 HUMAN|HGNC=19083|UniProtKB=P61024 P61024 CKS1B PTHR23415:SF42 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;cyclin binding#GO:0030332;enzyme regulator activity#GO:0030234;histone binding#GO:0042393;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;ubiquitin binding#GO:0043130;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;regulation of mitotic cell cycle#GO:0007346 SCF ubiquitin ligase complex#GO:0019005;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695 scaffold/adaptor protein#PC00226 HUMAN|HGNC=4417|UniProtKB=P46926 P46926 GNPDA1 PTHR11280:SF8 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE ISOMERASE 1 identical protein binding#GO:0042802;hydrolase activity#GO:0016787;protein binding#GO:0005515;isomerase activity#GO:0016853;binding#GO:0005488;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;UDP-N-acetylglucosamine metabolic process#GO:0006047;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;organic acid catabolic process#GO:0016054;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;amino sugar catabolic process#GO:0046348;amino sugar metabolic process#GO:0006040;aromatic compound biosynthetic process#GO:0019438;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 isomerase#PC00135 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 HUMAN|HGNC=24883|UniProtKB=Q9NSD7 Q9NSD7 RXFP3 PTHR24230:SF70 G-PROTEIN COUPLED RECEPTOR RELAXIN-3 RECEPTOR 1 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=11999|UniProtKB=Q12888 Q12888 TP53BP1 PTHR15321:SF3 TUMOR SUPPRESSOR P53-BINDING PROTEIN 1 TP53-BINDING PROTEIN 1 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;cell cycle checkpoint#GO:0000075;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;DNA damage checkpoint#GO:0000077;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 HUMAN|HGNC=33702|UniProtKB=Q5XKP0 Q5XKP0 MICOS13 PTHR31816:SF3 MICOS COMPLEX SUBUNIT MIC13 MICOS COMPLEX SUBUNIT MIC13 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cristae formation#GO:0042407;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;organelle membrane contact site#GO:0044232;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=8052|UniProtKB=Q9UKK9 Q9UKK9 NUDT5 PTHR11839:SF24 UDP/ADP-SUGAR PYROPHOSPHATASE ADP-SUGAR PYROPHOSPHATASE pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 pyrophosphatase#PC00196 HUMAN|HGNC=12417|UniProtKB=P23258 P23258 TUBG1 PTHR11588:SF62 TUBULIN TUBULIN GAMMA-1 CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;organelle organization#GO:0006996;protein polymerization#GO:0051258;cell cycle#GO:0007049;organelle fission#GO:0048285 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;gamma-tubulin complex#GO:0000930;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 tubulin#PC00228 HUMAN|HGNC=26190|UniProtKB=Q8NCE2 Q8NCE2 MTMR14 PTHR13524:SF2 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 14 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181 HUMAN|HGNC=31103|UniProtKB=Q8NHR9 Q8NHR9 PFN4 PTHR11604:SF2 PROFILIN PROFILIN-4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;maintenance of location#GO:0051235;negative regulation of actin filament polymerization#GO:0030837;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular#GO:0005622 non-motor actin binding protein#PC00165 HUMAN|HGNC=9723|UniProtKB=P11216 P11216 PYGB PTHR11468:SF29 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, BRAIN FORM transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;transferase activity, transferring glycosyl groups#GO:0016757;anion binding#GO:0043168;ion binding#GO:0043167 glucan metabolic process#GO:0044042;macromolecule catabolic process#GO:0009057;glycogen metabolic process#GO:0005977;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;cellular glucan metabolic process#GO:0006073;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 HUMAN|HGNC=7890|UniProtKB=Q9HBY0 Q9HBY0 NOX3 PTHR11972:SF12 NADPH OXIDASE NADPH OXIDASE 3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;oxidoreductase complex#GO:1990204;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175 HUMAN|HGNC=14632|UniProtKB=Q8N6G6 Q8N6G6 ADAMTSL1 PTHR13723:SF157 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=18002|UniProtKB=Q9NS69 Q9NS69 TOMM22 PTHR12504:SF3 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG primary active transporter#PC00068 HUMAN|HGNC=28873|UniProtKB=Q7Z7D3 Q7Z7D3 VTCN1 PTHR24100:SF0 BUTYROPHILIN V-SET DOMAIN-CONTAINING T-CELL ACTIVATION INHIBITOR 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=9994|UniProtKB=O14924 O14924 RGS12 PTHR45945:SF1 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G-PROTEIN SIGNALING 12 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=15921|UniProtKB=Q9UKM9 Q9UKM9 RALY PTHR13968:SF6 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN RALY nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=15582|UniProtKB=Q8WXI7 Q8WXI7 MUC16 PTHR14672:SF1 MUCIN-16 MUCIN-16 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=14007|UniProtKB=Q9H1Y3 Q9H1Y3 OPN3 PTHR24240:SF171 OPSIN OPSIN-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to abiotic stimulus#GO:0071214;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=31859|UniProtKB=Q6ZTA4 Q6ZTA4 TRIM67 PTHR24099:SF21 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED TRIPARTITE MOTIF-CONTAINING PROTEIN 67 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=23800|UniProtKB=Q9P2F8 Q9P2F8 SIPA1L2 PTHR15711:SF7 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 2 GTPase-activating protein#PC00257 HUMAN|HGNC=29851|UniProtKB=Q86UW6 Q86UW6 N4BP2 PTHR46535:SF1 NEDD4-BINDING PROTEIN 2 NEDD4-BINDING PROTEIN 2 HUMAN|HGNC=27945|UniProtKB=Q8IYA8 Q8IYA8 IHO1 PTHR35662:SF1 INTERACTOR OF HORMAD1 PROTEIN 1 INTERACTOR OF HORMAD1 PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;meiosis I cell cycle phase#GO:0098764;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;meiotic DNA double-strand break formation#GO:0042138;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;nucleic acid phosphodiester bond hydrolysis#GO:0090305;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;cell cycle#GO:0007049;organelle fission#GO:0048285;biological phase#GO:0044848 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=25500|UniProtKB=Q8IYM2 Q8IYM2 SLFN12 PTHR12155:SF42 SCHLAFEN SCHLAFEN FAMILY MEMBER 12 HUMAN|HGNC=4096|UniProtKB=O75293 O75293 GADD45B PTHR10411:SF5 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 BETA regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 p53 pathway#P00059>GADD45#G01575;p53 pathway#P00059>GADD45#P04626 HUMAN|HGNC=25745|UniProtKB=Q9H9L3 Q9H9L3 ISG20L2 PTHR12801:SF78 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED INTERFERON-STIMULATED 20 KDA EXONUCLEASE-LIKE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;signal transduction by p53 class mediator#GO:0072331;cellular process#GO:0009987;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;signaling#GO:0023052;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 exoribonuclease#PC00099 HUMAN|HGNC=3778|UniProtKB=P02751 P02751 FN1 PTHR19143:SF267 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRONECTIN carbohydrate derivative binding#GO:0097367;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;cell-substrate junction assembly#GO:0007044;system development#GO:0048731;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Integrin signalling pathway#P00034>Fibronectin#P00939 HUMAN|HGNC=19956|UniProtKB=Q92537 Q92537 SUSD6 PTHR46839:SF2 SUSHI DOMAIN-CONTAINING PROTEIN 6 SUSHI DOMAIN-CONTAINING PROTEIN 6 HUMAN|HGNC=12694|UniProtKB=P32241 P32241 VIPR1 PTHR45620:SF24 PDF RECEPTOR-LIKE PROTEIN-RELATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=9705|UniProtKB=P15151 P15151 PVR PTHR23277:SF109 NECTIN-RELATED POLIOVIRUS RECEPTOR cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;biological adhesion#GO:0022610 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 HUMAN|HGNC=2760|UniProtKB=Q9H4E7 Q9H4E7 DEF6 PTHR14383:SF2 SWAP-70 RECOMBINASE DIFFERENTIALLY EXPRESSED IN FDCP 6 HOMOLOG cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6708|UniProtKB=P48449 P48449 LSS PTHR11764:SF20 TERPENE CYCLASE/MUTASE FAMILY MEMBER LANOSTEROL SYNTHASE cyclase#PC00079 Cholesterol biosynthesis#P00014>Anosterol synthase#P00497 HUMAN|HGNC=15685|UniProtKB=O43505 O43505 B4GAT1 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 transferase#PC00220 HUMAN|HGNC=8876|UniProtKB=P17858 P17858 PFKL PTHR13697:SF14 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, LIVER TYPE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;carbon-carbon lyase activity#GO:0016830;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;fructose-bisphosphate aldolase activity#GO:0004332;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;carbohydrate binding#GO:0030246;isomerase activity#GO:0016853;kinase activity#GO:0016301;oxidoreductase activity#GO:0016491;cation binding#GO:0043169;carbon-oxygen lyase activity#GO:0016835;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;hydro-lyase activity#GO:0016836;intramolecular transferase activity#GO:0016866;organic cyclic compound binding#GO:0097159;identical protein binding#GO:0042802;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glucose metabolic process#GO:0006006;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;hexose metabolic process#GO:0019318;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphofructokinase-1#P00672 HUMAN|HGNC=6380|UniProtKB=Q96E93 Q96E93 KLRG1 PTHR47648:SF1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY G MEMBER 1 KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY G MEMBER 1 transmembrane signal receptor#PC00197 HUMAN|HGNC=27905|UniProtKB=Q68DK7 Q68DK7 MSL1 PTHR21656:SF2 MALE-SPECIFIC LETHAL-1 PROTEIN MALE-SPECIFIC LETHAL 1 HOMOLOG binding#GO:0005488;chromatin binding#GO:0003682 peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;histone H4 acetylation#GO:0043967;chromatin organization#GO:0006325;histone H4-K16 acetylation#GO:0043984;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=29568|UniProtKB=Q7Z7J7 Q7Z7J7 LHFPL4 PTHR12489:SF14 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 4 PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;sensory perception of sound#GO:0007605;system process#GO:0003008;cellular component organization#GO:0016043;nervous system process#GO:0050877;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular macromolecule localization#GO:0070727;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;receptor clustering#GO:0043113 synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 HUMAN|HGNC=4539|UniProtKB=Q9GZN0 Q9GZN0 GPR88 PTHR24240:SF165 OPSIN G-PROTEIN COUPLED RECEPTOR 88-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to abiotic stimulus#GO:0071214;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=16860|UniProtKB=Q15020 Q15020 SART3 PTHR15481:SF5 RIBONUCLEIC ACID BINDING PROTEIN S1 SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNIZED BY T-CELLS 3 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=1804|UniProtKB=P31358 P31358 CD52 PTHR15029:SF0 CAMPATH-1 ANTIGEN CAMPATH-1 ANTIGEN cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;positive regulation of cytosolic calcium ion concentration#GO:0007204;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;B axonemal microtubule#GO:0097650;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 HUMAN|HGNC=23423|UniProtKB=Q4JDL3 Q4JDL3 PTPN20 PTHR45706:SF2 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 20 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195 HUMAN|HGNC=6476|UniProtKB=P18627 P18627 LAG3 PTHR11890:SF18 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER LYMPHOCYTE ACTIVATION GENE 3 PROTEIN signaling receptor activity#GO:0038023;protein binding#GO:0005515;molecular transducer activity#GO:0060089;MHC protein binding#GO:0042287;binding#GO:0005488;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=4831|UniProtKB=P69891 P69891 HBG1 PTHR11442:SF94 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT GAMMA-1 small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;intracellular#GO:0005622;extracellular region#GO:0005576 HUMAN|HGNC=7878|UniProtKB=Q9NZN8 Q9NZN8 CNOT2 PTHR23326:SF3 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;intracellular#GO:0005622;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 general transcription factor#PC00259 HUMAN|HGNC=20316|UniProtKB=Q86TN4 Q86TN4 TRPT1 PTHR12684:SF2 PUTATIVE PHOSPHOTRANSFERASE TRNA 2'-PHOSPHOTRANSFERASE 1 catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=17794|UniProtKB=Q7L0Q8 Q7L0Q8 RHOU PTHR24072:SF148 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOU GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;membrane organization#GO:0061024;transport#GO:0006810;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;vesicle organization#GO:0016050;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;phagocytosis#GO:0006909;regulation of organelle organization#GO:0033043;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036;apoptotic cell clearance#GO:0043277 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 small GTPase#PC00208 Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;Axon guidance mediated by netrin#P00009>cdc42#P00364 HUMAN|HGNC=20123|UniProtKB=Q86U10 Q86U10 ASPG PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE HUMAN|HGNC=26602|UniProtKB=Q6ZTU2 Q6ZTU2 EP400P1 PTHR46459:SF2 E1A-BINDING PROTEIN P400-RELATED E1A-BINDING PROTEIN P400-RELATED Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=10936|UniProtKB=Q16572 Q16572 SLC18A3 PTHR23506:SF13 FAMILY NOT NAMED VESICULAR ACETYLCHOLINE TRANSPORTER ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215;cation transmembrane transporter activity#GO:0008324 chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;synaptic signaling#GO:0099536;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;vacuole#GO:0005773;terminal bouton#GO:0043195;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;axon terminus#GO:0043679;membrane coat#GO:0030117;intracellular#GO:0005622;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;trans-Golgi network transport vesicle#GO:0030140;clathrin-coated pit#GO:0005905;presynapse#GO:0098793;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell junction#GO:0030054;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;axon#GO:0030424;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;transport vesicle#GO:0030133;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>VAChT#P01078;Nicotinic acetylcholine receptor signaling pathway#P00044>VAChT#P01089;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>VAChT#P01065 HUMAN|HGNC=7799|UniProtKB=O00221 O00221 NFKBIE PTHR24118:SF37 POTE ANKYRIN DOMAIN NF-KAPPA-B INHIBITOR EPSILON membrane traffic protein#PC00150 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Toll receptor signaling pathway#P00054>IkappaB#P01338 HUMAN|HGNC=8048|UniProtKB=P36639 P36639 NUDT1 PTHR43758:SF2 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE phosphatase#PC00181 HUMAN|HGNC=17164|UniProtKB=Q9BXK5 Q9BXK5 BCL2L13 PTHR15758:SF2 BCL-2-LIKE PROTEIN 13 BCL-2-LIKE PROTEIN 13 HUMAN|HGNC=17354|UniProtKB=Q96AK3 Q96AK3 APOBEC3D PTHR13857:SF24 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3D RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363 response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;RNA phosphodiester bond hydrolysis#GO:0090501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;defense response to virus#GO:0051607;demethylation#GO:0070988;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;transposition#GO:0032196;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;RNA-dependent DNA biosynthetic process#GO:0006278;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;nucleic acid phosphodiester bond hydrolysis#GO:0090305;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147 HUMAN|HGNC=15870|UniProtKB=Q9BUV8 Q9BUV8 RAB5IF PTHR12906:SF0 PROTEIN C20ORF24 RAB5-INTERACTING PROTEIN RESPIRASOME COMPLEX ASSEMBLY FACTOR 1 HUMAN|HGNC=27267|UniProtKB=Q2TB10 Q2TB10 ZNF800 PTHR21020:SF0 UNCHARACTERIZED ZINC FINGER PROTEIN 800 HUMAN|HGNC=26002|UniProtKB=Q86V15 Q86V15 CASZ1 PTHR12451:SF0 TRANSCRIPTION FACTOR CASTOR PROTEIN MING -RELATED ZINC FINGER PROTEIN CASTOR HOMOLOG 1 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;regulation of neuron differentiation#GO:0045664;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=29256|UniProtKB=A7XYQ1 A7XYQ1 SOBP PTHR23186:SF2 RETINOIC ACID-INDUCED PROTEIN 2 SINE OCULIS-BINDING PROTEIN HOMOLOG HUMAN|HGNC=12741|UniProtKB=Q15056 Q15056 EIF4H PTHR23236:SF11 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4H translation initiation factor#PC00224 HUMAN|HGNC=20254|UniProtKB=O60291 O60291 MGRN1 PTHR22996:SF2 MAHOGUNIN E3 UBIQUITIN-PROTEIN LIGASE MGRN1 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;negative regulation of intracellular signal transduction#GO:1902532;transport#GO:0006810;regulation of signaling#GO:0023051;protein modification process#GO:0036211;endosome to lysosome transport#GO:0008333;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;lysosomal transport#GO:0007041;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;protein modification by small protein conjugation or removal#GO:0070647;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;localization#GO:0051179;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 endosome#GO:0005768;nucleus#GO:0005634;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=11055|UniProtKB=P48029 P48029 SLC6A8 PTHR11616:SF96 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;neurotransmitter binding#GO:0042165;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 HUMAN|HGNC=13504|UniProtKB=Q8N6H7 Q8N6H7 ARFGAP2 PTHR45686:SF10 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 vesicle targeting, to, from or within Golgi#GO:0048199;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;Golgi vesicle budding#GO:0048194;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;establishment of organelle localization#GO:0051656 GTPase-activating protein#PC00257 HUMAN|HGNC=2911|UniProtKB=P36957 P36957 DLST PTHR43416:SF18 DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL transferase#PC00220 HUMAN|HGNC=28440|UniProtKB=Q68CQ4 Q68CQ4 DIEXF PTHR12933:SF0 ORF PROTEIN-RELATED DIGESTIVE ORGAN EXPANSION FACTOR HOMOLOG snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=29245|UniProtKB=Q8NET4 Q8NET4 RTL9 PTHR47702:SF1 RETROTRANSPOSON GAG-LIKE PROTEIN 9 RETROTRANSPOSON GAG-LIKE PROTEIN 9 viral or transposable element protein#PC00237 HUMAN|HGNC=1073|UniProtKB=P22004 P22004 BMP6 PTHR11848:SF137 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 6 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP6/7#P06752;TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=11275|UniProtKB=Q01082 Q01082 SPTBN1 PTHR11915:SF226 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 1 HUMAN|HGNC=29259|UniProtKB=Q7L7X3 Q7L7X3 TAOK1 PTHR48015:SF31 SERINE/THREONINE-PROTEIN KINASE TAO SERINE/THREONINE-PROTEIN KINASE TAO1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;plasma membrane bounded cell projection assembly#GO:0120031;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;execution phase of apoptosis#GO:0097194;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;cell death#GO:0008219;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=19688|UniProtKB=Q96NY8 Q96NY8 NECTIN4 PTHR23277:SF11 NECTIN-RELATED NECTIN-4 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;biological adhesion#GO:0022610 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 HUMAN|HGNC=9781|UniProtKB=P20338 P20338 RAB4A PTHR47979:SF73 DRAB11-RELATED RAS-RELATED PROTEIN RAB-4A regulation of endocytosis#GO:0030100;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;vesicle organization#GO:0016050 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=10067|UniProtKB=P78317 P78317 RNF4 PTHR23041:SF78 RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF4 HUMAN|HGNC=20952|UniProtKB=Q9P0S9 Q9P0S9 TMEM14C PTHR12668:SF4 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14C-RELATED localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;transport#GO:0006810 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 HUMAN|HGNC=11184|UniProtKB=Q00796 Q00796 SORD PTHR43161:SF9 SORBITOL DEHYDROGENASE SORBITOL DEHYDROGENASE dehydrogenase#PC00092 HUMAN|HGNC=23603|UniProtKB=O75690 O75690 KRTAP5-8 PTHR23262:SF212 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-8 HUMAN|HGNC=3556|UniProtKB=P12104 P12104 FABP2 PTHR11955:SF89 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, INTESTINAL HUMAN|HGNC=14129|UniProtKB=Q96KQ7 Q96KQ7 EHMT2 PTHR46307:SF1 G9A, ISOFORM B HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2 HUMAN|HGNC=16492|UniProtKB=Q86V87 Q86V87 FAM160B2 PTHR21705:SF9 RAI16 PROTEIN-RELATED PROTEIN FAM160B2 HUMAN|HGNC=15927|UniProtKB=Q9Y282 Q9Y282 ERGIC3 PTHR10984:SF25 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=17072|UniProtKB=Q8IUD2 Q8IUD2 ERC1 PTHR18861:SF1 ELKS/RAB6-INTERACTING/CAST PROTEIN ELKS/RAB6-INTERACTING/CAST FAMILY MEMBER 1 membrane traffic protein#PC00150 HUMAN|HGNC=19682|UniProtKB=Q8TF76 Q8TF76 HASPIN PTHR24419:SF18 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE/THREONINE-PROTEIN KINASE HASPIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=13936|UniProtKB=O95867 O95867 LY6G6C PTHR32149:SF2 LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6C LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6C HUMAN|HGNC=26641|UniProtKB=A1L4H1 A1L4H1 SSC5D PTHR19331:SF329 SCAVENGER RECEPTOR DOMAIN-CONTAINING SOLUBLE SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN SSC5D response to organic substance#GO:0010033;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;response to chemical#GO:0042221;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;detection of stimulus#GO:0051606;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;detection of chemical stimulus#GO:0009593 serine protease#PC00203 HUMAN|HGNC=20709|UniProtKB=Q9NWH9 Q9NWH9 SLTM PTHR15683:SF5 SCAFFOLD ATTACHMENT FACTOR B-RELATED SAFB-LIKE TRANSCRIPTION MODULATOR sequence-specific DNA binding#GO:0043565;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;mRNA processing#GO:0006397;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4076|UniProtKB=P47869 P47869 GABRA2 PTHR18945:SF218 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-2 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;cell junction#GO:0030054;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=6004|UniProtKB=Q6UXL0 Q6UXL0 IL20RB PTHR20859:SF48 INTERFERON/INTERLEUKIN RECEPTOR INTERLEUKIN-20 RECEPTOR SUBUNIT BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=15751|UniProtKB=Q9H115 Q9H115 NAPB PTHR13768:SF12 SOLUBLE NSF ATTACHMENT PROTEIN SNAP BETA-SOLUBLE NSF ATTACHMENT PROTEIN syntaxin binding#GO:0019905;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of neurotransmitter secretion#GO:0046928;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;secretion#GO:0046903;regulation of secretion#GO:0051046;synaptic signaling#GO:0099536;regulation of exocytosis#GO:0017157;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of cellular localization#GO:0060341;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;protein transport#GO:0015031;regulation of trans-synaptic signaling#GO:0099177;intracellular transport#GO:0046907;export from cell#GO:0140352;vesicle fusion#GO:0006906;cellular protein complex disassembly#GO:0043624;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of signaling#GO:0023051;transport#GO:0006810;protein-containing complex assembly#GO:0065003;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular component disassembly#GO:0022411;regulation of protein-containing complex assembly#GO:0043254;regulation of transport#GO:0051049;neurotransmitter transport#GO:0006836;signal release#GO:0023061;vesicle organization#GO:0016050;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;cellular process#GO:0009987;localization#GO:0051179;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;synaptic transmission, glutamatergic#GO:0035249;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;cell junction#GO:0030054;SNARE complex#GO:0031201;vacuole#GO:0005773;terminal bouton#GO:0043195;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;axon#GO:0030424;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=19888|UniProtKB=Q9H8L6 Q9H8L6 MMRN2 PTHR15427:SF6 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER MULTIMERIN-2 HUMAN|HGNC=14648|UniProtKB=Q2VYF4 Q2VYF4 LETM2 PTHR14009:SF7 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN LETM1 DOMAIN-CONTAINING PROTEIN LETM2, MITOCHONDRIAL cellular chemical homeostasis#GO:0055082;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;metal ion homeostasis#GO:0055065;cellular ion homeostasis#GO:0006873 secondary carrier transporter#PC00258 HUMAN|HGNC=217|UniProtKB=Q9UHI8 Q9UHI8 ADAMTS1 PTHR13723:SF40 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=29821|UniProtKB=Q9NPH2 Q9NPH2 ISYNA1 PTHR11510:SF5 MYO-INOSITOL-1 PHOSPHATE SYNTHASE INOSITOL-3-PHOSPHATE SYNTHASE 1 isomerase activity#GO:0016853;catalytic activity#GO:0003824 organic hydroxy compound metabolic process#GO:1901615;carbohydrate biosynthetic process#GO:0016051;alcohol biosynthetic process#GO:0046165;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular carbohydrate metabolic process#GO:0044262;small molecule biosynthetic process#GO:0044283;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 isomerase#PC00135 HUMAN|HGNC=24153|UniProtKB=Q8N111 Q8N111 CEND1 PTHR36683:SF1 CELL CYCLE EXIT AND NEURONAL DIFFERENTIATION PROTEIN 1 CELL CYCLE EXIT AND NEURONAL DIFFERENTIATION PROTEIN 1 head development#GO:0060322;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;brain development#GO:0007420;central nervous system neuron differentiation#GO:0021953;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;nervous system development#GO:0007399;anatomical structure formation involved in morphogenesis#GO:0048646;localization#GO:0051179;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;generation of neurons#GO:0048699;cell migration#GO:0016477;locomotion#GO:0040011 HUMAN|HGNC=20174|UniProtKB=Q9NVM9 Q9NVM9 INTS13 PTHR12955:SF1 SARCOMA ANTIGEN NY-SAR-95-RELATED INTEGRATOR COMPLEX SUBUNIT 13 cellular localization#GO:0051641;organelle localization#GO:0051640;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;centrosome localization#GO:0051642;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 HUMAN|HGNC=15860|UniProtKB=O94906 O94906 PRPF6 PTHR11246:SF1 PRE-MRNA SPLICING FACTOR PRE-MRNA-PROCESSING FACTOR 6 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=15891|UniProtKB=Q9NVA1 Q9NVA1 UQCC1 PTHR12184:SF1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;cytochrome complex assembly#GO:0017004;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex III assembly#GO:0034551;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;mitochondrial respiratory chain complex assembly#GO:0033108;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;translation#GO:0006412;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;mitochondrion organization#GO:0007005;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 chaperone#PC00072 HUMAN|HGNC=6654|UniProtKB=O60663 O60663 LMX1B PTHR24208:SF96 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1-BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=9472|UniProtKB=Q99538 Q99538 LGMN PTHR12000:SF38 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;vacuolar protein processing#GO:0006624;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cysteine protease#PC00081 HUMAN|HGNC=10560|UniProtKB=O15265 O15265 ATXN7 PTHR15117:SF2 ATAXIN 7 RELATED ATAXIN-7 HUMAN|HGNC=16086|UniProtKB=Q96NB2 Q96NB2 SFXN2 PTHR11153:SF14 SIDEROFLEXIN SIDEROFLEXIN-2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068 HUMAN|HGNC=30450|UniProtKB=Q6XQN6 Q6XQN6 NAPRT PTHR11098:SF1 NICOTINATE PHOSPHORIBOSYLTRANSFERASE NICOTINATE PHOSPHORIBOSYLTRANSFERASE glycosyltransferase#PC00111 HUMAN|HGNC=9229|UniProtKB=O14495 O14495 PLPP3 PTHR10165:SF79 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=34303|UniProtKB=Q6ZNQ3 Q6ZNQ3 LRRC69 PTHR45752:SF1 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 69 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|HGNC=23333|UniProtKB=Q9NRG1 Q9NRG1 PRTFDC1 PTHR43340:SF5 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE PHOSPHORIBOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;transferase activity#GO:0016740;magnesium ion binding#GO:0000287;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase metabolic process#GO:0009112;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pigment biosynthetic process#GO:0046148;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;IMP metabolic process#GO:0046040;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase biosynthetic process#GO:0009113;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 glycosyltransferase#PC00111 Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245;Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247 HUMAN|HGNC=20474|UniProtKB=Q8IU68 Q8IU68 TMC8 PTHR23302:SF39 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 8 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215 HUMAN|HGNC=14764|UniProtKB=Q8NGJ7 Q8NGJ7 OR51A2 PTHR26450:SF168 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51A2-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=5474|UniProtKB=P24593 P24593 IGFBP5 PTHR11551:SF4 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 5 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=4204|UniProtKB=Q8N0V5 Q8N0V5 GCNT2 PTHR19297:SF183 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER N-ACETYLLACTOSAMINIDE BETA-1,6-N-ACETYLGLUCOSAMINYL-TRANSFERASE glycosyltransferase#PC00111 HUMAN|HGNC=16181|UniProtKB=Q8TEL6 Q8TEL6 TRPC4AP PTHR31743:SF1 TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN TCPC4AP SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 HUMAN|HGNC=13628|UniProtKB=Q8WXS5 Q8WXS5 CACNG8 PTHR12107:SF2 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-8 SUBUNIT calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;cation channel activity#GO:0005261;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 cellular localization#GO:0051641;membrane organization#GO:0061024;system process#GO:0003008;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;anterograde trans-synaptic signaling#GO:0098916;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;regulation of transmembrane transporter activity#GO:0022898;positive regulation of signaling#GO:0023056;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;establishment of protein localization to vacuole#GO:0072666;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;protein localization to synapse#GO:0035418;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of ion transmembrane transport#GO:0034765;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein localization to cell junction#GO:1902414;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;regulation of trans-synaptic signaling#GO:0099177;regulation of ion transport#GO:0043269;multicellular organismal process#GO:0032501;protein-containing complex localization#GO:0031503;receptor localization to synapse#GO:0097120;signal transduction#GO:0007165;regulation of neurotransmitter receptor activity#GO:0099601;receptor internalization#GO:0031623;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;action potential#GO:0001508;cation transport#GO:0006812;ionotropic glutamate receptor signaling pathway#GO:0035235;cation transmembrane transport#GO:0098655;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;vacuolar transport#GO:0007034;protein localization to membrane#GO:0072657;regulation of membrane potential#GO:0042391;protein localization to vacuole#GO:0072665;ion transport#GO:0006811;establishment of protein localization to organelle#GO:0072594;regulation of AMPA receptor activity#GO:2000311;nervous system process#GO:0050877;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;protein localization to cell periphery#GO:1990778;localization#GO:0051179;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of synaptic transmission#GO:0050806;synaptic transmission, glutamatergic#GO:0035249 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;organelle#GO:0043226;integral component of membrane#GO:0016021;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=25655|UniProtKB=Q9NUJ3 Q9NUJ3 TCP11L1 PTHR12832:SF15 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11-LIKE PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|Gene=YH009_HUMAN|UniProtKB=A8MV72 A8MV72 - PTHR11639:SF71 S100 CALCIUM-BINDING PROTEIN UPF0607 PROTEIN ENSP00000332738-RELATED protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=20219|UniProtKB=Q6IN85 Q6IN85 PPP4R3A PTHR23318:SF3 ATP SYNTHASE GAMMA-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3A ATP synthase#PC00002 HUMAN|HGNC=4604|UniProtKB=P19876 P19876 CXCL3 PTHR10179:SF82 CXC CHEMOKINE C-X-C MOTIF CHEMOKINE 3 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=30366|UniProtKB=Q92545 Q92545 TMEM131 PTHR22050:SF1 RW1 PROTEIN HOMOLOG TRANSMEMBRANE PROTEIN 131 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=10906|UniProtKB=Q12908 Q12908 SLC10A2 PTHR10361:SF19 SODIUM-BILE ACID COTRANSPORTER ILEAL SODIUM/BILE ACID COTRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068 HUMAN|HGNC=22951|UniProtKB=Q7Z3F1 Q7Z3F1 GPR155 PTHR22829:SF5 DEP DOMAIN PROTEIN INTEGRAL MEMBRANE PROTEIN GPR155 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=13353|UniProtKB=Q9BXW4 Q9BXW4 MAP1LC3C PTHR10969:SF50 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3C enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;whole membrane#GO:0098805 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=23296|UniProtKB=Q96KN9 Q96KN9 GJD4 PTHR11984:SF3 CONNEXIN GAP JUNCTION DELTA-4 PROTEIN gap junction#PC00105 HUMAN|HGNC=13109|UniProtKB=P17038 P17038 ZNF43 PTHR24376:SF154 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 43-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=18161|UniProtKB=Q96I15 Q96I15 SCLY PTHR11601:SF34 CYSTEINE DESULFURYLASE FAMILY MEMBER CYSTEINE DESULFURASE, MITOCHONDRIAL-RELATED lyase#PC00144 HUMAN|HGNC=25748|UniProtKB=Q96GJ1 Q96GJ1 TRMT2B PTHR45904:SF1 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL(54)-C(5))-METHYLTRANSFERASE HOMOLOG RNA methyltransferase#PC00033 HUMAN|HGNC=30396|UniProtKB=Q9BQE4 Q9BQE4 SELENOS PTHR28621:SF1 SELENOPROTEIN S SELENOPROTEIN S cellular localization#GO:0051641;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;peptide transport#GO:0015833;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;regulation of cellular process#GO:0050794;protein transport#GO:0015031;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;organonitrogen compound catabolic process#GO:1901565;amide transport#GO:0042886;organic substance transport#GO:0071702;response to unfolded protein#GO:0006986;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;ubiquitin-dependent ERAD pathway#GO:0030433;intracellular protein transport#GO:0006886;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=9671|UniProtKB=P23470 P23470 PTPRG PTHR19134:SF468 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE GAMMA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=9038|UniProtKB=P39877 P39877 PLA2G5 PTHR11716:SF10 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2 GROUP V cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipase activity#GO:0004620;anion binding#GO:0043168;phospholipid binding#GO:0005543 monocarboxylic acid transport#GO:0015718;regulation of cell-cell adhesion#GO:0022407;organic acid transport#GO:0015849;cell population proliferation#GO:0008283;lipid transport#GO:0006869;regulation of T cell activation#GO:0050863;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;establishment of localization#GO:0051234;leukocyte proliferation#GO:0070661;secretion#GO:0046903;anion transport#GO:0006820;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;negative regulation of T cell proliferation#GO:0042130;negative regulation of T cell activation#GO:0050868;organic anion transport#GO:0015711;cellular metabolic process#GO:0044237;cell adhesion#GO:0007155;negative regulation of leukocyte activation#GO:0002695;primary metabolic process#GO:0044238;negative regulation of cell adhesion#GO:0007162;cell activation#GO:0001775;regulation of cellular process#GO:0050794;organophosphate metabolic process#GO:0019637;lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;transport#GO:0006810;phospholipid metabolic process#GO:0006644;leukocyte cell-cell adhesion#GO:0007159;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance transport#GO:0071702;T cell proliferation#GO:0042098;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;lipid localization#GO:0010876;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cell population proliferation#GO:0042127;lymphocyte activation#GO:0046649;ion transport#GO:0006811;carboxylic acid transport#GO:0046942;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;regulation of T cell proliferation#GO:0042129;localization#GO:0051179;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;cellular lipid metabolic process#GO:0044255;long-chain fatty acid transport#GO:0015909 phospholipase#PC00186 HUMAN|HGNC=31045|UniProtKB=Q96JW4 Q96JW4 SLC41A2 PTHR16228:SF25 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SOLUTE CARRIER FAMILY 41 MEMBER 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=12658|UniProtKB=P52735 P52735 VAV2 PTHR45818:SF4 PROTEIN VAV GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV2 B cell activation#P00010>vav#P00368;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169 HUMAN|HGNC=4832|UniProtKB=P69892 P69892 HBG2 PTHR11442:SF89 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT GAMMA-2 small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;intracellular#GO:0005622;extracellular region#GO:0005576 HUMAN|HGNC=43880|UniProtKB=A0A0U1RRI6 A0A0U1RRI6 CENPVL3 PTHR28620:SF7 CENTROMERE PROTEIN V CENTROMERE PROTEIN V-LIKE PROTEIN 3 HUMAN|HGNC=16366|UniProtKB=Q96PE6 Q96PE6 ZIM3 PTHR24377:SF30 IP01015P-RELATED ZINC FINGER IMPRINTED 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24828|UniProtKB=Q96AM1 Q96AM1 MRGPRF PTHR11334:SF3 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MEMBER F signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=29466|UniProtKB=Q5T753 Q5T753 LCE1E PTHR23263:SF140 SMALL PROLINE-RICH PROTEIN LATE CORNIFIED ENVELOPE PROTEIN 1E HUMAN|HGNC=10974|UniProtKB=Q9UHI7 Q9UHI7 SLC23A1 PTHR11119:SF21 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER SOLUTE CARRIER FAMILY 23 MEMBER 1 transporter#PC00227 HUMAN|HGNC=4251|UniProtKB=P36268 P36268 GGT2 PTHR11686:SF56 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 1 PROENZYME-RELATED transferase activity, transferring acyl groups#GO:0016746;hydrolase activity#GO:0016787;transferase activity#GO:0016740;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of response to external stimulus#GO:0032101;sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of inflammatory response#GO:0050727;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;regulation of defense response#GO:0031347;biological regulation#GO:0065007;catabolic process#GO:0009056;regulation of immune system process#GO:0002682;organic substance catabolic process#GO:1901575;defense response#GO:0006952;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190 HUMAN|HGNC=8621|UniProtKB=P23759 P23759 PAX7 PTHR45636:SF26 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=25708|UniProtKB=Q96JM4 Q96JM4 LRRIQ1 PTHR46652:SF3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED HUMAN|HGNC=6252|UniProtKB=Q9ULD8 Q9ULD8 KCNH3 PTHR10217:SF481 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=4067|UniProtKB=O95166 O95166 GABARAP PTHR10969:SF20 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;signaling receptor binding#GO:0005102;ubiquitin-like protein ligase binding#GO:0044389 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;whole membrane#GO:0098805 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=9570|UniProtKB=P61289 P61289 PSME3 PTHR10660:SF4 PROTEASOME REGULATOR PA28 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 3 protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;proteasomal protein catabolic process#GO:0010498;regulation of G1/S transition of mitotic cell cycle#GO:2000045;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;cell cycle phase transition#GO:0044770;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;mitotic cell cycle phase transition#GO:0044772;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;positive regulation of catalytic activity#GO:0043085;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of mitotic cell cycle#GO:0007346 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Cell cycle#P00013>Proteasome#P00480 HUMAN|HGNC=25095|UniProtKB=Q66K64 Q66K64 DCAF15 PTHR28541:SF1 DDB1- AND CUL4-ASSOCIATED FACTOR 15 DDB1- AND CUL4-ASSOCIATED FACTOR 15 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 HUMAN|HGNC=34497|UniProtKB=A6NGS2 A6NGS2 ERICH4 PTHR36879:SF1 GLUTAMATE-RICH PROTEIN 4 GLUTAMATE-RICH PROTEIN 4 HUMAN|HGNC=9192|UniProtKB=P19388 P19388 POLR2E PTHR10535:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 HUMAN|HGNC=375|UniProtKB=P24588 P24588 AKAP5 PTHR15182:SF0 A-KINASE ANCHOR PROTEIN 5-RELATED A-KINASE ANCHOR PROTEIN 5 protein kinase A binding#GO:0051018;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;enzyme binding#GO:0019899;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 regulation of lyase activity#GO:0051339;regulation of adenylate cyclase activity#GO:0045761;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;regulation of cyclase activity#GO:0031279;positive regulation of molecular function#GO:0044093;biological regulation#GO:0065007;regulation of catalytic activity#GO:0050790 synapse#GO:0045202;postsynaptic specialization#GO:0099572;somatodendritic compartment#GO:0036477;postsynaptic density#GO:0014069;leading edge membrane#GO:0031256;cell junction#GO:0030054;dendrite#GO:0030425;cell projection membrane#GO:0031253;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=5392|UniProtKB=P46695 P46695 IER3 PTHR16915:SF0 IMMEDIATE EARLY RESPONSE 3 RADIATION-INDUCIBLE IMMEDIATE-EARLY GENE IEX-1 CCKR signaling map#P06959>IEX1#P07092;CCKR signaling map#P06959>IEX1#G07263;CCKR signaling map#P06959>IEX1#G06970 HUMAN|HGNC=4609|UniProtKB=P30550 P30550 GRPR PTHR45695:SF7 LEUCOKININ RECEPTOR-RELATED GASTRIN-RELEASING PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=17687|UniProtKB=Q9Y2P8 Q9Y2P8 RCL1 PTHR11096:SF1 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;ligase activity#GO:0016874;cyclase activity#GO:0009975;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;endonucleolytic cleavage involved in rRNA processing#GO:0000478;cleavage involved in rRNA processing#GO:0000469;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=8698|UniProtKB=Q9Y5H2 Q9Y5H2 PCDHGA11 PTHR24028:SF84 CADHERIN-87A PROTOCADHERIN GAMMA-A11 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=29100|UniProtKB=Q5JTH9 Q5JTH9 RRP12 PTHR21576:SF119 UNCHARACTERIZED NODULIN-LIKE PROTEIN RRP12-LIKE PROTEIN HUMAN|HGNC=13149|UniProtKB=P36508 P36508 ZNF76 PTHR23226:SF222 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 76 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=12516|UniProtKB=P55089 P55089 UCN PTHR15035:SF11 CORTICOLIBERIN/UROCORTIN UROCORTIN peptide hormone#PC00179 HUMAN|HGNC=21024|UniProtKB=Q14999 Q14999 CUL7 PTHR22771:SF3 CULLIN AND GALACTOSE-BINDING DOMAIN-CONTAINING CULLIN-7 HUMAN|HGNC=32672|UniProtKB=Q9BRX9 Q9BRX9 WDR83 PTHR22842:SF3 WD40 REPEAT PROTEIN WD REPEAT DOMAIN-CONTAINING PROTEIN 83 HUMAN|HGNC=2610|UniProtKB=P11509 P11509 CYP2A6 PTHR24300:SF180 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2A6 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 Nicotine degradation#P05914>CYP2A6#P05984 HUMAN|HGNC=7473|UniProtKB=Q9UBK8 Q9UBK8 MTRR PTHR19384:SF84 NITRIC OXIDE SYNTHASE-RELATED METHIONINE SYNTHASE REDUCTASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidoreductase#PC00176 HUMAN|HGNC=8244|UniProtKB=Q9H210 Q9H210 OR2D2 PTHR26453:SF156 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2D2 transmembrane signal receptor#PC00197 HUMAN|HGNC=17149|UniProtKB=Q96IQ7 Q96IQ7 VSIG2 PTHR45046:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 2 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=5835|UniProtKB=P06315 P06315 IGKV5-2 PTHR23267:SF313 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 5-2 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=30424|UniProtKB=Q8TCT6 Q8TCT6 SPPL3 PTHR12174:SF22 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 3 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;signal peptide processing#GO:0006465;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 bounding membrane of organelle#GO:0098588;leaflet of membrane bilayer#GO:0097478;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;Golgi-associated vesicle membrane#GO:0030660;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789;cytoplasmic side of membrane#GO:0098562 aspartic protease#PC00053 HUMAN|HGNC=9942|UniProtKB=P23942 P23942 PRPH2 PTHR19282:SF202 TETRASPANIN PERIPHERIN-2 protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=4191|UniProtKB=P01275 P01275 GCG PTHR11418:SF0 GLUCAGON PRO-GLUCAGON CCKR signaling map#P06959>GCG#G07291;CCKR signaling map#P06959>GCG#G06997 HUMAN|HGNC=35236|UniProtKB=A8MZ36 A8MZ36 EVPLL PTHR23169:SF7 ENVOPLAKIN ENVOPLAKIN-RELATED cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;wound healing#GO:0042060;cellular process#GO:0009987;intermediate filament cytoskeleton organization#GO:0045104 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intracellular#GO:0005622;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 intermediate filament binding protein#PC00130 HUMAN|HGNC=15090|UniProtKB=Q8N148 Q8N148 OR6V1 PTHR26454:SF10 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6V1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=28026|UniProtKB=Q7Z572 Q7Z572 SPATA21 PTHR47500:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 21 calmodulin-related#PC00061 HUMAN|HGNC=3582|UniProtKB=O15360 O15360 FANCA PTHR12047:SF2 FANCONI ANEMIA GROUP A PROTEIN FANCONI ANEMIA GROUP A PROTEIN membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;Fanconi anaemia nuclear complex#GO:0043240;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=34391|UniProtKB=Q4AC99 Q4AC99 ACCSL PTHR43795:SF1 BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED INACTIVE 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE-LIKE PROTEIN 2-RELATED transaminase#PC00216 HUMAN|HGNC=30455|UniProtKB=Q6UXG3 Q6UXG3 CD300LG PTHR11860:SF62 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 9 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=3041|UniProtKB=Q14206 Q14206 RCAN2 PTHR10300:SF5 CALCIPRESSIN CALCIPRESSIN-2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;protein serine/threonine phosphatase activity#GO:0004722;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;regulation of signaling#GO:0023051;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 intercellular signal molecule#PC00207 HUMAN|HGNC=10409|UniProtKB=P63220 P63220 RPS21 PTHR10442:SF15 40S RIBOSOMAL PROTEIN S21 40S RIBOSOMAL PROTEIN S21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;cleavage involved in rRNA processing#GO:0000469;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;endonucleolytic cleavage involved in rRNA processing#GO:0000478;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=28669|UniProtKB=Q8NE28 Q8NE28 STKLD1 PTHR24363:SF5 SERINE/THREONINE PROTEIN KINASE SERINE/THREONINE KINASE-LIKE DOMAIN-CONTAINING PROTEIN STKLD1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=26666|UniProtKB=Q32P44 Q32P44 EML3 PTHR13720:SF15 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819 HUMAN|HGNC=3346|UniProtKB=Q14249 Q14249 ENDOG PTHR13966:SF18 ENDONUCLEASE RELATED ENDONUCLEASE G, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;ribonuclease activity#GO:0004540;catalytic activity, acting on DNA#GO:0140097;endodeoxyribonuclease activity#GO:0004520;deoxyribonuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;heterocycle catabolic process#GO:0046700;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;nucleobase-containing compound metabolic process#GO:0006139;plasma membrane bounded cell projection organization#GO:0120036;cellular nitrogen compound catabolic process#GO:0044270;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;DNA catabolic process, endonucleolytic#GO:0000737;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;cell projection assembly#GO:0030031;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;plasma membrane bounded cell projection assembly#GO:0120031;DNA metabolic process#GO:0006259 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 Apoptosis signaling pathway#P00006>endoG#P00279 HUMAN|HGNC=26655|UniProtKB=Q8NA82 Q8NA82 MARCHF10 PTHR14471:SF5 MARCH7/10 E3 UBIQUITIN PROTEIN LIGASE FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF10-RELATED ubiquitin-protein ligase#PC00234 HUMAN|HGNC=2642|UniProtKB=Q02928 Q02928 CYP4A11 PTHR24291:SF39 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4A11-RELATED oxygenase#PC00177 HUMAN|HGNC=1622|UniProtKB=Q99832 Q99832 CCT7 PTHR11353:SF22 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ETA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 chaperonin#PC00073 HUMAN|HGNC=22916|UniProtKB=Q9C0B9 Q9C0B9 ZCCHC2 PTHR46939:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=16062|UniProtKB=Q6UUV9 Q6UUV9 CRTC1 PTHR13589:SF14 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 1 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Gonadotropin-releasing hormone receptor pathway#P06664>TORC1#P06788 HUMAN|HGNC=26138|UniProtKB=Q6ZN57 Q6ZN57 ZFP2 PTHR23226:SF329 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 2 HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=24639|UniProtKB=Q96N28 Q96N28 PRELID3A PTHR11158:SF23 MSF1/PX19 RELATED PRELI DOMAIN CONTAINING PROTEIN 3A binding#GO:0005488;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 HUMAN|HGNC=1785|UniProtKB=P46527 P46527 CDKN1B PTHR10265:SF9 CYCLIN-DEPENDENT KINASE INHIBITOR 1 CYCLIN-DEPENDENT KINASE INHIBITOR 1B cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;cyclin binding#GO:0030332;enzyme regulator activity#GO:0030234;chaperone binding#GO:0051087;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;protein kinase activity#GO:0004672;cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 negative regulation of biological process#GO:0048519;mitotic cell cycle phase transition#GO:0044772;regulation of cell population proliferation#GO:0042127;negative regulation of cell cycle#GO:0045786;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell population proliferation#GO:0008283;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle arrest#GO:0007050;G1/S transition of mitotic cell cycle#GO:0000082;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;negative regulation of cell population proliferation#GO:0008285;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase inhibitor#PC00139 Interleukin signaling pathway#P00036>p27KIP1#P00982 HUMAN|HGNC=21407|UniProtKB=Q53H80 Q53H80 AKIRIN2 PTHR13293:SF8 UNCHARACTERIZED AKIRIN-2 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;aromatic compound biosynthetic process#GO:0019438;positive regulation of defense response#GO:0031349;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;regulation of response to external stimulus#GO:0032101;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;positive regulation of response to biotic stimulus#GO:0002833;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=21785|UniProtKB=Q5RL73 Q5RL73 RBM48 PTHR20957:SF1 UNCHARACTERIZED RNA-BINDING PROTEIN 48 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4095|UniProtKB=P24522 P24522 GADD45A PTHR10411:SF3 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 ALPHA regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 p38 MAPK pathway#P05918>GADD45#P06044;p53 pathway#P00059>GADD45#G01575;PI3 kinase pathway#P00048>GADD45#G01544;p53 pathway#P00059>GADD45#P04626 HUMAN|HGNC=14476|UniProtKB=Q9NX20 Q9NX20 MRPL16 PTHR12220:SF13 50S/60S RIBOSOMAL PROTEIN L16 39S RIBOSOMAL PROTEIN L16, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 ribosomal protein#PC00202 HUMAN|HGNC=6066|UniProtKB=P08476 P08476 INHBA PTHR11848:SF133 TGF-BETA FAMILY INHIBIN BETA A CHAIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inhba#P06723;TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>Inhba/b#P06700 HUMAN|HGNC=14686|UniProtKB=P57087 P57087 JAM2 PTHR44663:SF2 JUNCTIONAL ADHESION MOLECULE B JUNCTIONAL ADHESION MOLECULE B HUMAN|HGNC=28152|UniProtKB=Q9BU64 Q9BU64 CENPO PTHR14582:SF1 INNER KINETOCHORE SUBUNIT MAL2 CENTROMERE PROTEIN O membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;kinetochore#GO:0000776;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;condensed chromosome, centromeric region#GO:0000779;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;condensed nuclear chromosome kinetochore#GO:0000778;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;chromosomal region#GO:0098687 HUMAN|HGNC=29043|UniProtKB=Q6XUX3 Q6XUX3 DSTYK PTHR46392:SF1 DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=33577|UniProtKB=A4QPH2 A4QPH2 PI4KAP2 PTHR10048:SF15 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE ALPHA-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;phosphatidylinositol phosphorylation#GO:0046854;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 kinase#PC00137 HUMAN|HGNC=6518|UniProtKB=Q14739 Q14739 LBR PTHR21257:SF52 DELTA(14)-STEROL REDUCTASE DELTA(14)-STEROL REDUCTASE LBR oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;steroid metabolic process#GO:0008202;lipid metabolic process#GO:0006629;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 reductase#PC00198 HUMAN|HGNC=11957|UniProtKB=Q93074 Q93074 MED12 PTHR46007:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=6080|UniProtKB=O15357 O15357 INPPL1 PTHR46051:SF2 SH2 DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 5-PHOSPHATASE 2 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SHIP#P00839;PI3 kinase pathway#P00048>SHIP#P01200;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>SHIP2#P00897 HUMAN|HGNC=25597|UniProtKB=Q9NV72 Q9NV72 ZNF701 PTHR24377:SF800 IP01015P-RELATED ZINC FINGER PROTEIN 701 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26032|UniProtKB=Q7L5N7 Q7L5N7 LPCAT2 PTHR23063:SF21 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE 2 acyltransferase#PC00042 HUMAN|HGNC=20476|UniProtKB=Q9H596 Q9H596 DUSP21 PTHR46495:SF1 DUAL SPECIFICITY PROTEIN PHOSPHATASE 21 DUAL SPECIFICITY PROTEIN PHOSPHATASE 21 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=10888|UniProtKB=Q9NPC8 Q9NPC8 SIX2 PTHR10390:SF29 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;kidney development#GO:0001822;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;urogenital system development#GO:0001655;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 HUMAN|HGNC=20482|UniProtKB=Q96P53 Q96P53 WDFY2 PTHR46189:SF3 LD41958P WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=29373|UniProtKB=Q9C099 Q9C099 LRRCC1 PTHR15454:SF34 NISCHARIN RELATED LEUCINE-RICH REPEAT AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17407|UniProtKB=Q5HYM0 Q5HYM0 ZC3H12B PTHR12876:SF27 N4BP1-RELATED RIBONUCLEASE ZC3H12B-RELATED catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 endoribonuclease#PC00094 HUMAN|HGNC=17881|UniProtKB=Q8IZ57 Q8IZ57 NRSN1 PTHR14796:SF6 NEURENSIN 1-RELATED NEURENSIN-1 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 somatodendritic compartment#GO:0036477;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;neuronal cell body#GO:0043025;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell body#GO:0044297;neuron projection#GO:0043005;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=3765|UniProtKB=P36888 P36888 FLT3 PTHR24416:SF356 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to cytokine#GO:0034097;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;hemopoiesis#GO:0030097;B cell activation#GO:0042113;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;positive regulation of biological process#GO:0048518;signaling#GO:0023052;leukocyte activation#GO:0045321;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;immune system development#GO:0002520;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;immune system process#GO:0002376;response to stimulus#GO:0050896;B cell differentiation#GO:0030183;lymphocyte differentiation#GO:0030098;positive regulation of phosphate metabolic process#GO:0045937;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=20772|UniProtKB=Q13509 Q13509 TUBB3 PTHR11588:SF43 TUBULIN TUBULIN BETA-3 CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 HUMAN|HGNC=26270|UniProtKB=Q9H5I5 Q9H5I5 PIEZO2 PTHR13167:SF24 UNCHARACTERIZED PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;cellular response to stimulus#GO:0051716;response to mechanical stimulus#GO:0009612;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to environmental stimulus#GO:0104004 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=4453|UniProtKB=P78333 P78333 GPC5 PTHR10822:SF12 GLYPICAN GLYPICAN-5 cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;positive regulation of Wnt signaling pathway#GO:0030177;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;regulation of protein localization#GO:0032880;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;protein localization to membrane#GO:0072657;regulation of protein localization to membrane#GO:1905475;localization of cell#GO:0051674;cell communication#GO:0007154;cell motility#GO:0048870;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of canonical Wnt signaling pathway#GO:0060828;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=16162|UniProtKB=Q8N2H4 Q8N2H4 SYS1 PTHR12952:SF0 SYS1 PROTEIN SYS1 HOMOLOG protein localization to plasma membrane#GO:0072659;Golgi to endosome transport#GO:0006895;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=21041|UniProtKB=Q9UBI9 Q9UBI9 HECA PTHR13425:SF3 HEADCASE PROTEIN HEADCASE PROTEIN HOMOLOG HUMAN|HGNC=37138|UniProtKB=B4DXR9 B4DXR9 ZNF732 PTHR24384:SF81 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 732 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=19748|UniProtKB=Q8N9L9 Q8N9L9 ACOT4 PTHR10824:SF6 ACYL-COENZYME A THIOESTERASE-RELATED PEROXISOMAL SUCCINYL-COENZYME A THIOESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 esterase#PC00097 HUMAN|HGNC=1096|UniProtKB=O95861 O95861 BPNT1 PTHR43028:SF5 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 phosphatase#PC00181 HUMAN|HGNC=9701|UniProtKB=Q00577 Q00577 PURA PTHR12611:SF2 PUR-TRANSCRIPTIONAL ACTIVATOR TRANSCRIPTIONAL ACTIVATOR PROTEIN PUR-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=27735|UniProtKB=Q8N4F7 Q8N4F7 RNF175 PTHR13407:SF2 RNF121 PROTEIN RING FINGER PROTEIN 175 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;ubiquitin-dependent ERAD pathway#GO:0030433;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=27713|UniProtKB=Q6ZMS4 Q6ZMS4 ZNF852 PTHR24377:SF827 IP01015P-RELATED ZINC FINGER PROTEIN 852 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26511|UniProtKB=O14558 O14558 HSPB6 PTHR45640:SF2 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-6 HUMAN|HGNC=20178|UniProtKB=Q86VE0 Q86VE0 MYPOP PTHR32345:SF3 MYB-RELATED TRANSCRIPTION FACTOR, PARTNER OF PROFILIN MYB-RELATED TRANSCRIPTION FACTOR, PARTNER OF PROFILIN cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=8609|UniProtKB=O95453 O95453 PARN PTHR15092:SF44 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 POLY(A)-SPECIFIC RIBONUCLEASE PARN catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;heterocyclic compound binding#GO:1901363;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=21608|UniProtKB=Q9Y383 Q9Y383 LUC7L2 PTHR12375:SF28 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN LUC7-LIKE 2-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=22247|UniProtKB=Q8NEG2 Q8NEG2 C7orf57 PTHR31097:SF2 SI:DKEY-276J7.1 CHROMOSOME 4 C7ORF57 HOMOLOG HUMAN|HGNC=2981|UniProtKB=Q9ULA0 Q9ULA0 DNPEP PTHR28570:SF3 ASPARTYL AMINOPEPTIDASE ASPARTYL AMINOPEPTIDASE metalloprotease#PC00153 HUMAN|HGNC=24635|UniProtKB=Q7RTY5 Q7RTY5 PRSS48 PTHR24256:SF309 TRYPTASE-RELATED SERINE PROTEASE 48 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=25248|UniProtKB=Q9H0B8 Q9H0B8 CRISPLD2 PTHR10334:SF64 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN LCCL DOMAIN-CONTAINING 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=29051|UniProtKB=O75071 O75071 EFCAB14 PTHR15717:SF2 PROTEIN KIAA0494 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 14 HUMAN|HGNC=4810|UniProtKB=Q9NYQ3 Q9NYQ3 HAO2 PTHR10578:SF139 S -2-HYDROXY-ACID OXIDASE-RELATED HYDROXYACID OXIDASE 2 oxidoreductase#PC00176 HUMAN|HGNC=5343|UniProtKB=Q05084 Q05084 ICA1 PTHR10164:SF3 ISLET CELL AUTOANTIGEN 1 ISLET CELL AUTOANTIGEN 1 biological regulation#GO:0065007;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=10854|UniProtKB=O60902 O60902 SHOX2 PTHR46255:SF1 SHORT STATURE HOMEOBOX SHORT STATURE HOMEOBOX PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=28732|UniProtKB=P0C862 P0C862 C1QTNF9 PTHR15427:SF21 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q AND TUMOR NECROSIS FACTOR-RELATED PROTEIN 9A-RELATED HUMAN|HGNC=25505|UniProtKB=Q9H8J5 Q9H8J5 MANSC1 PTHR16021:SF7 MANSC DOMAIN CONTAINING PROTEIN 1 MANSC DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=2202|UniProtKB=P02462 P02462 COL4A1 PTHR24023:SF854 COLLAGEN ALPHA COLLAGEN ALPHA-1(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=15349|UniProtKB=Q8NGC7 Q8NGC7 OR11H6 PTHR24242:SF90 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H6 G-protein coupled receptor#PC00021 HUMAN|HGNC=18174|UniProtKB=Q9P289 Q9P289 STK26 PTHR48012:SF7 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE/THREONINE-PROTEIN KINASE 26 HUMAN|HGNC=16261|UniProtKB=Q8IVM8 Q8IVM8 SLC22A9 PTHR24064:SF592 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 9 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258 HUMAN|HGNC=17045|UniProtKB=Q969G9 Q969G9 NKD1 PTHR22611:SF2 PROTEIN NAKED CUTICLE PROTEIN NAKED CUTICLE HOMOLOG 1 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of cell communication#GO:0010648;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Wnt signaling pathway#P00057>Naked#P01427 HUMAN|HGNC=1932|UniProtKB=P36222 P36222 CHI3L1 PTHR11177:SF202 CHITINASE CHITINASE-3-LIKE PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;carbohydrate derivative binding#GO:0097367;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;binding#GO:0005488;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110 HUMAN|HGNC=29385|UniProtKB=Q8NB42 Q8NB42 ZNF527 PTHR24377:SF620 IP01015P-RELATED ZINC FINGER PROTEIN 527 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=7513|UniProtKB=Q02505 Q02505 MUC3A PTHR24041:SF22 MUCIN MUCIN-3A-RELATED cell adhesion molecule#PC00069 HUMAN|HGNC=7448|UniProtKB=Q13496 Q13496 MTM1 PTHR10807:SF69 MYOTUBULARIN-RELATED MYOTUBULARIN hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;proteolysis#GO:0006508;negative regulation of cellular component organization#GO:0051129;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;glycerophospholipid metabolic process#GO:0006650;regulation of macroautophagy#GO:0016241;negative regulation of autophagy#GO:0010507;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;mitochondrion distribution#GO:0048311;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;organophosphate metabolic process#GO:0019637;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;developmental process#GO:0032502;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular homeostasis#GO:0019725;regulation of autophagosome assembly#GO:2000785;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;process utilizing autophagic mechanism#GO:0061919;glycerolipid metabolic process#GO:0046486;negative regulation of organelle organization#GO:0010639;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;phospholipid dephosphorylation#GO:0046839;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;phosphatidylinositol metabolic process#GO:0046488;regulation of cellular catabolic process#GO:0031329;negative regulation of macroautophagy#GO:0016242;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;localization#GO:0051179;organelle assembly#GO:0070925;negative regulation of catabolic process#GO:0009895;organelle organization#GO:0006996;dephosphorylation#GO:0016311;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=9063|UniProtKB=Q15111 Q15111 PLCL1 PTHR10336:SF102 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN INACTIVE PHOSPHOLIPASE C-LIKE PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 HUMAN|HGNC=12511|UniProtKB=P17480 P17480 UBTF PTHR46318:SF4 UPSTREAM BINDING TRANSCRIPTION FACTOR NUCLEOLAR TRANSCRIPTION FACTOR 1 DNA-binding transcription factor#PC00218 General transcription by RNA polymerase I#P00022>UBF1#P00655 HUMAN|HGNC=13526|UniProtKB=Q9Y2B5 Q9Y2B5 VPS9D1 PTHR23101:SF98 RAB GDP/GTP EXCHANGE FACTOR VPS9 DOMAIN-CONTAINING PROTEIN 1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=2388|UniProtKB=P02489 P02489 CRYAA PTHR45640:SF14 HEAT SHOCK PROTEIN HSP-12.2-RELATED ALPHA-CRYSTALLIN A CHAIN-RELATED VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 HUMAN|HGNC=6585|UniProtKB=P22888 P22888 LHCGR PTHR24372:SF1 GLYCOPROTEIN HORMONE RECEPTOR LUTROPIN-CHORIOGONADOTROPIC HORMONE RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 reproductive system development#GO:0061458;regulation of adenylate cyclase activity#GO:0045761;rhythmic process#GO:0048511;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;hormone-mediated signaling pathway#GO:0009755;reproductive structure development#GO:0048608;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;reproductive process#GO:0022414;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of phospholipase C activity#GO:0010863;multicellular organismal reproductive process#GO:0048609;male sex differentiation#GO:0046661;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;regulation of phospholipase C activity#GO:1900274;sex differentiation#GO:0007548;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;positive regulation of hydrolase activity#GO:0051345;developmental process involved in reproduction#GO:0003006;regulation of response to stimulus#GO:0048583;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;cAMP-mediated signaling#GO:0019933;positive regulation of lipase activity#GO:0060193;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of cyclase activity#GO:0031279;animal organ development#GO:0048513;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;regulation of catalytic activity#GO:0050790;system development#GO:0048731;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;multicellular organism reproduction#GO:0032504;multicellular organism development#GO:0007275;positive regulation of phospholipase activity#GO:0010518;male gonad development#GO:0008584;cellular process#GO:0009987;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;biological regulation#GO:0065007;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=7842|UniProtKB=P08949 P08949 NMB PTHR16866:SF3 GASTRIN-RELEASING PEPTIDE NEUROMEDIN-B neuropeptide hormone activity#GO:0005184;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;hormone secretion#GO:0046879;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;regulation of hormone secretion#GO:0046883;signal release#GO:0023061;hormone transport#GO:0009914;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;positive regulation of secretion#GO:0051047;positive regulation of transport#GO:0051050;cell communication#GO:0007154;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;positive regulation of cellular process#GO:0048522;positive regulation of hormone secretion#GO:0046887;localization#GO:0051179;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;export from cell#GO:0140352 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=28541|UniProtKB=Q8N5U0 Q8N5U0 C11orf42 PTHR36872:SF1 GENE 5901-RELATED GENE 5901-RELATED HUMAN|HGNC=6360|UniProtKB=Q9UKR0 Q9UKR0 KLK12 PTHR24271:SF63 KALLIKREIN-RELATED KALLIKREIN-12 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=16877|UniProtKB=O95140 O95140 MFN2 PTHR10465:SF1 TRANSMEMBRANE GTPASE FZO1 MITOFUSIN-2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 localization#GO:0051179;mitochondrial fusion#GO:0008053;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;organelle localization#GO:0051640;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;organelle fusion#GO:0048284 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=17932|UniProtKB=Q9UHV2 Q9UHV2 SERTAD1 PTHR16277:SF12 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 SERTA DOMAIN-CONTAINING PROTEIN 1 molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=11819|UniProtKB=Q9Y5J7 Q9Y5J7 TIMM9 PTHR13172:SF2 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9 primary active transporter#PC00068 HUMAN|HGNC=11136|UniProtKB=Q92966 Q92966 SNAPC3 PTHR13421:SF16 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;core promoter sequence-specific DNA binding#GO:0001046;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 general transcription factor#PC00259 HUMAN|HGNC=4216|UniProtKB=O95390 O95390 GDF11 PTHR11848:SF166 TGF-BETA FAMILY GROWTH/DIFFERENTIATION FACTOR 11 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=10001|UniProtKB=O15539 O15539 RGS5 PTHR10845:SF42 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 5 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=1212|UniProtKB=O95466 O95466 FMNL1 PTHR45857:SF2 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;localization of cell#GO:0051674;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;anatomical structure development#GO:0048856;regulation of cell morphogenesis#GO:0022604;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=16946|UniProtKB=Q92791 Q92791 P3H4 PTHR13986:SF4 PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT ENDOPLASMIC RETICULUM PROTEIN SC65 collagen binding#GO:0005518;protein-containing complex binding#GO:0044877;binding#GO:0005488 peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;collagen fibril organization#GO:0030199;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;nitrogen compound metabolic process#GO:0006807;supramolecular fiber organization#GO:0097435;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=27196|UniProtKB=Q8IYB9 Q8IYB9 ZNF595 PTHR24377:SF303 IP01015P-RELATED ZINC FINGER PROTEIN 595 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=13620|UniProtKB=Q8NFZ0 Q8NFZ0 FBH1 PTHR11070:SF30 UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER F-BOX DNA HELICASE 1 pyrophosphatase activity#GO:0016462;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009 HUMAN|HGNC=31864|UniProtKB=P0DM35 P0DM35 MT1HL1 PTHR23299:SF53 METALLOTHIONEIN METALLOTHIONEIN 1H-LIKE PROTEIN 1-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;transition metal ion homeostasis#GO:0055076;response to metal ion#GO:0010038;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;response to toxic substance#GO:0009636;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11088|UniProtKB=Q9H2G2 Q9H2G2 SLK PTHR48012:SF11 STERILE20-LIKE KINASE, ISOFORM B-RELATED STE20-LIKE SERINE/THREONINE-PROTEIN KINASE HUMAN|HGNC=17969|UniProtKB=A8MPY1 A8MPY1 GABRR3 PTHR18945:SF196 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-3 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;system process#GO:0003008;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=9595|UniProtKB=P43115 P43115 PTGER3 PTHR11866:SF10 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;organic acid binding#GO:0043177;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;divalent inorganic cation homeostasis#GO:0072507;system process#GO:0003008;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of localization#GO:0032879;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;secretion#GO:0046903;regulation of secretion#GO:0051046;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of phospholipase C activity#GO:0010863;regulation of lyase activity#GO:0051339;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular cation homeostasis#GO:0030003;regulation of multicellular organismal process#GO:0051239;smooth muscle contraction#GO:0006939;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;negative regulation of transport#GO:0051051;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of response to stimulus#GO:0048583;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to stress#GO:0006950;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;transport#GO:0006810;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;regulation of system process#GO:0044057;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;negative regulation of multicellular organismal process#GO:0051241;regulation of transport#GO:0051049;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;digestion#GO:0007586;biological regulation#GO:0065007;muscle system process#GO:0003012;cyclic-nucleotide-mediated signaling#GO:0019935;muscle contraction#GO:0006936 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836;PI3 kinase pathway#P00048>GPCR#P01204 HUMAN|HGNC=11469|UniProtKB=O00267 O00267 SUPT5H PTHR11125:SF7 SUPPRESSOR OF TY 5 TRANSCRIPTION ELONGATION FACTOR SPT5 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;transcription elongation from RNA polymerase II promoter#GO:0006368;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023 HUMAN|HGNC=26848|UniProtKB=Q8N808 Q8N808 SLC35G3 PTHR22911:SF32 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G3-RELATED intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=24285|UniProtKB=Q96DB5 Q96DB5 RMDN1 PTHR16056:SF16 UNCHARACTERIZED REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 1 HUMAN|HGNC=24927|UniProtKB=O43745 O43745 CHP2 PTHR46002:SF6 EG:114D9.1 PROTEIN-RELATED CALCINEURIN B HOMOLOGOUS PROTEIN 2 HUMAN|HGNC=30798|UniProtKB=Q9BZD7 Q9BZD7 PRRG3 PTHR24251:SF12 OVOCHYMASE-RELATED TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 3 serine protease#PC00203 HUMAN|HGNC=196|UniProtKB=Q9Y3Q7 Q9Y3Q7 ADAM18 PTHR11905:SF158 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 18 cell recognition#GO:0008037;fertilization#GO:0009566;reproduction#GO:0000003;single fertilization#GO:0007338;biological adhesion#GO:0022610;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell adhesion#GO:0007155;sperm-egg recognition#GO:0035036;cellular process#GO:0009987;multi-organism reproductive process#GO:0044703;multi-organism process#GO:0051704;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=1909|UniProtKB=O15335 O15335 CHAD PTHR24373:SF277 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN CHONDROADHERIN extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=15023|UniProtKB=Q8NHC6 Q8NHC6 OR14L1P PTHR26452:SF806 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A16-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=12379|UniProtKB=Q15631 Q15631 TSN PTHR10741:SF2 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9845|UniProtKB=O60896 O60896 RAMP3 PTHR14076:SF2 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular localization#GO:0051641;membrane organization#GO:0061024;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;anatomical structure morphogenesis#GO:0009653;membrane invagination#GO:0010324;establishment of localization#GO:0051234;tube morphogenesis#GO:0035239;divalent inorganic cation transport#GO:0072511;vasculature development#GO:0001944;organic substance metabolic process#GO:0071704;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;blood vessel morphogenesis#GO:0048514;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;tube development#GO:0035295;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;protein transport#GO:0015031;blood vessel development#GO:0001568;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;receptor internalization#GO:0031623;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;transport#GO:0006810;cation transport#GO:0006812;calcium ion transport#GO:0006816;amide transport#GO:0042886;system development#GO:0048731;organic substance transport#GO:0071702;divalent metal ion transport#GO:0070838;response to endogenous stimulus#GO:0009719;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;cellular response to chemical stimulus#GO:0070887;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;ion transport#GO:0006811;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;localization#GO:0051179;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;biological regulation#GO:0065007 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 HUMAN|HGNC=4450|UniProtKB=Q8N158 Q8N158 GPC2 PTHR10822:SF24 GLYPICAN GLYPICAN-2 cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule localization#GO:0033036;smoothened signaling pathway#GO:0007224;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;regulation of protein localization to membrane#GO:1905475;regulation of localization#GO:0032879;localization of cell#GO:0051674;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;regulation of protein localization#GO:0032880 cell junction#GO:0030054;cell surface#GO:0009986;extracellular matrix#GO:0031012;synapse#GO:0045202;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=21528|UniProtKB=Q9NR28 Q9NR28 DIABLO PTHR32247:SF3 DIABLO HOMOLOG, MITOCHONDRIAL DIABLO HOMOLOG, MITOCHONDRIAL neuron apoptotic process#GO:0051402;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;neuron death#GO:0070997;response to oxidative stress#GO:0006979;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;regulation of cellular process#GO:0050794;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;cellular response to stress#GO:0033554;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;signal transduction#GO:0007165;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of metabolic process#GO:0009893;positive regulation of programmed cell death#GO:0043068;cell death#GO:0008219;cellular response to oxidative stress#GO:0034599;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell death#GO:0010942 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 Apoptosis signaling pathway#P00006>Smac/Diablo#P00309 HUMAN|HGNC=26176|UniProtKB=Q9H6H4 Q9H6H4 REEP4 PTHR12300:SF36 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;cytoplasmic microtubule#GO:0005881;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;microtubule#GO:0005874;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 HUMAN|HGNC=16050|UniProtKB=Q86YW9 Q86YW9 MED12L PTHR46007:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12-LIKE PROTEIN transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=15882|UniProtKB=Q9NV79 Q9NV79 PCMTD2 PTHR11579:SF2 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 2 transferase activity#GO:0016740;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 methyltransferase#PC00155 HUMAN|HGNC=2987|UniProtKB=Q14185 Q14185 DOCK1 PTHR45653:SF1 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 1 guanyl-nucleotide exchange factor#PC00113 Integrin signalling pathway#P00034>Dock180#P00930 HUMAN|HGNC=18886|UniProtKB=P59534 P59534 TAS2R39 PTHR11394:SF47 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 1-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=6012|UniProtKB=P26951 P26951 IL3RA PTHR23036:SF179 CYTOKINE RECEPTOR INTERLEUKIN-3 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=2768|UniProtKB=P35659 P35659 DEK PTHR13468:SF1 DEK PROTEIN PROTEIN DEK protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of double-strand break repair#GO:2000779;double-strand break repair#GO:0006302;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;regulation of DNA repair#GO:0006282;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|Gene=NSG2|UniProtKB=Q9Y328 Q9Y328 NSG2 PTHR28546:SF2 NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 endosomal transport#GO:0016197;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cellular protein-containing complex assembly#GO:0034622;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex subunit organization#GO:0043933 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=8709|UniProtKB=Q9Y5G2 Q9Y5G2 PCDHGB2 PTHR24028:SF144 CADHERIN-87A PROTOCADHERIN GAMMA-B2 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=6658|UniProtKB=O00534 O00534 VWA5A PTHR45737:SF6 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A HUMAN|HGNC=18437|UniProtKB=Q8TDQ0 Q8TDQ0 HAVCR2 PTHR15498:SF73 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING TIM HEPATITIS A VIRUS CELLULAR RECEPTOR 2 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=29262|UniProtKB=Q9P2H3 Q9P2H3 IFT80 PTHR24098:SF11 OUTER SEGMENT 5 INTRAFLAGELLAR TRANSPORT PROTEIN 80 HOMOLOG vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=4599|UniProtKB=Q14831 Q14831 GRM7 PTHR24060:SF98 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 7 adenylate cyclase activity#GO:0004016;amino acid binding#GO:0016597;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;carboxylic acid binding#GO:0031406;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;glutamate binding#GO:0016595 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=18969|UniProtKB=Q8NI17 Q8NI17 IL31RA PTHR23036:SF96 CYTOKINE RECEPTOR INTERLEUKIN-31 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=7941|UniProtKB=P23582 P23582 NPPC PTHR12167:SF2 C-TYPE NATRIURETIC PEPTIDE C-TYPE NATRIURETIC PEPTIDE receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;molecular function regulator#GO:0098772;protein binding#GO:0005515;hormone activity#GO:0005179;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;cyclic nucleotide metabolic process#GO:0009187;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>CNP#P06824;Gonadotropin-releasing hormone receptor pathway#P06664>CNP#G06905;Gonadotropin-releasing hormone receptor pathway#P06664>CNP#G06690 HUMAN|HGNC=31908|UniProtKB=A6NDE8 A6NDE8 GAGE12H PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=5967|UniProtKB=Q14626 Q14626 IL11RA PTHR23036:SF29 CYTOKINE RECEPTOR INTERLEUKIN-11 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;cellular response to organic substance#GO:0071310;positive regulation of cell population proliferation#GO:0008284;cell communication#GO:0007154;cell population proliferation#GO:0008283;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;positive regulation of biological process#GO:0048518;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=5385|UniProtKB=O43837 O43837 IDH3B PTHR11835:SF42 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;oxidation-reduction process#GO:0055114;secondary alcohol metabolic process#GO:1902652;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092 HUMAN|HGNC=17861|UniProtKB=Q8TDR0 Q8TDR0 TRAF3IP1 PTHR31363:SF0 TRAF3-INTERACTING PROTEIN 1 TRAF3-INTERACTING PROTEIN 1 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;regulation of microtubule-based process#GO:0032886;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;regulation of microtubule cytoskeleton organization#GO:0070507;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 supramolecular complex#GO:0099080;axoneme#GO:0005930;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;centriole#GO:0005814;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=17806|UniProtKB=Q6ZMK1 Q6ZMK1 CYHR1 PTHR23059:SF4 CYSTEINE AND HISTIDINE-RICH PROTEIN 1 CYSTEINE AND HISTIDINE-RICH PROTEIN 1 HUMAN|HGNC=18420|UniProtKB=Q9BYW2 Q9BYW2 SETD2 PTHR46711:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 histone modifying enzyme#PC00261 HUMAN|HGNC=16289|UniProtKB=Q9BZY9 Q9BZY9 TRIM31 PTHR24103:SF87 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM31 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=28393|UniProtKB=Q8IUW3 Q8IUW3 SPATA2L PTHR15326:SF7 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC SPERMATOGENESIS-ASSOCIATED PROTEIN 2-LIKE PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=12419|UniProtKB=Q9NRH3 Q9NRH3 TUBG2 PTHR11588:SF79 TUBULIN TUBULIN GAMMA-2 CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;organelle organization#GO:0006996;protein polymerization#GO:0051258;cell cycle#GO:0007049;organelle fission#GO:0048285 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;gamma-tubulin complex#GO:0000930;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 tubulin#PC00228 HUMAN|HGNC=6137|UniProtKB=P17301 P17301 ITGA2 PTHR23220:SF23 INTEGRIN ALPHA INTEGRIN ALPHA-2 integrin#PC00126 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=6724|UniProtKB=P51884 P51884 LUM PTHR45712:SF6 AGAP008170-PA LUMICAN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=17933|UniProtKB=Q9H7Z6 Q9H7Z6 KAT8 PTHR10615:SF82 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT8 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;histone binding#GO:0042393;N-acyltransferase activity#GO:0016410;histone acetyltransferase activity#GO:0004402;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;peptide-lysine-N-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;protein binding#GO:0005515;molecular function regulator#GO:0098772;H4 histone acetyltransferase activity#GO:0010485 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=32000|UniProtKB=P0DPF2 P0DPF2 NBPF20 PTHR14199:SF41 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 20 HUMAN|HGNC=13578|UniProtKB=Q5VUA4 Q5VUA4 ZNF318 PTHR15577:SF2 ZINC FINGER CONTAINING PROTEIN ZINC FINGER PROTEIN 318 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14644|UniProtKB=Q8NC67 Q8NC67 NETO2 PTHR24251:SF26 OVOCHYMASE-RELATED NEUROPILIN AND TOLLOID-LIKE PROTEIN 2 serine protease#PC00203 HUMAN|HGNC=7652|UniProtKB=O60934 O60934 NBN PTHR12162:SF0 NIBRIN-RELATED NIBRIN nucleic acid binding#GO:0003676;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;damaged DNA binding#GO:0003684;DNA-dependent ATPase activity#GO:0008094;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;telomere capping#GO:0016233;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;mitotic DNA integrity checkpoint#GO:0044774;cell cycle phase transition#GO:0044770;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;response to stress#GO:0006950;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;cellular response to stress#GO:0033554;cell cycle G2/M phase transition#GO:0044839;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;double-strand break repair#GO:0006302;mitotic cell cycle phase transition#GO:0044772;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;telomere maintenance#GO:0000723;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;signal transduction in response to DNA damage#GO:0042770;G2 DNA damage checkpoint#GO:0031572;DNA duplex unwinding#GO:0032508;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;mitotic DNA damage checkpoint#GO:0044773;homeostatic process#GO:0042592;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;mitotic G2 DNA damage checkpoint#GO:0007095;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;nuclear chromosome, telomeric region#GO:0000784;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;chromosomal region#GO:0098687 damaged DNA-binding protein#PC00086 HUMAN|Gene=PAPL|UniProtKB=Q6ZNF0 Q6ZNF0 ACP7 PTHR45867:SF3 PURPLE ACID PHOSPHATASE ACID PHOSPHATASE TYPE 7 phosphatase#PC00181 HUMAN|HGNC=5742|UniProtKB=A0A0C4DH72 A0A0C4DH72 IGKV1-6 PTHR23267:SF394 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-39-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=26189|UniProtKB=Q5VT66 Q5VT66 MTARC1 PTHR14237:SF25 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MITOCHONDRIAL AMIDOXIME-REDUCING COMPONENT 1 cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=31249|UniProtKB=Q5JQS5 Q5JQS5 OR2B11 PTHR26453:SF112 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2B11 transmembrane signal receptor#PC00197 HUMAN|HGNC=7981|UniProtKB=P43354 P43354 NR4A2 PTHR24085:SF0 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;signaling receptor binding#GO:0005102;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;hormone receptor binding#GO:0051427 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;central nervous system neuron differentiation#GO:0021953;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;response to peptide hormone#GO:0043434;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;organic cyclic compound biosynthetic process#GO:1901362;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=31256|UniProtKB=Q8NGX1 Q8NGX1 OR2T34 PTHR26453:SF4 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T3-RELATED transmembrane signal receptor#PC00197 HUMAN|Gene=UNQ5830/PRO19650/PRO19816|UniProtKB=Q6UY13 Q6UY13 UNQ5830/PRO19650/PRO19816 PTHR11471:SF3 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 HUMAN|HGNC=11208|UniProtKB=Q02447 Q02447 SP3 PTHR23235:SF3 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 CCKR signaling map#P06959>SP3#P07041 HUMAN|HGNC=29325|UniProtKB=Q6P9B6 Q6P9B6 MEAK7 PTHR23354:SF95 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED MTOR-ASSOCIATED PROTEIN MEAK7 HUMAN|HGNC=9865|UniProtKB=P10826 P10826 RARB PTHR24082:SF286 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=12674|UniProtKB=Q9Y277 Q9Y277 VDAC3 PTHR11743:SF28 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;inorganic anion transmembrane transporter activity#GO:0015103;channel activity#GO:0015267;transporter activity#GO:0005215 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 voltage-gated ion channel#PC00241 HUMAN|HGNC=7887|UniProtKB=Q9UNW9 Q9UNW9 NOVA2 PTHR10288:SF162 KH DOMAIN CONTAINING RNA BINDING PROTEIN RNA-BINDING PROTEIN NOVA-2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=23279|UniProtKB=A2CJ06 A2CJ06 DYTN PTHR12268:SF18 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROTELIN synaptic signaling#GO:0099536;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=16074|UniProtKB=Q9NX40 Q9NX40 OCIAD1 PTHR13336:SF4 OVARIAN CARCINOMA IMMUNOREACTIVE ANTIGEN OCIA DOMAIN-CONTAINING PROTEIN 1 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=28817|UniProtKB=Q96AG4 Q96AG4 LRRC59 PTHR45752:SF4 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 59 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|HGNC=12428|UniProtKB=Q15672 Q15672 TWIST1 PTHR23349:SF64 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TWIST-RELATED PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=1404|UniProtKB=O00305 O00305 CACNB4 PTHR11824:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-4 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;synaptic signaling#GO:0099536;divalent inorganic cation transport#GO:0072511;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;signaling#GO:0023052;cell-cell signaling#GO:0007267;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;regulation of calcium ion transport#GO:0051924;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;neuromuscular junction development#GO:0007528;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of ion transport#GO:0043269 membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411 HUMAN|HGNC=28504|UniProtKB=Q8TBZ0 Q8TBZ0 CCDC110 PTHR32083:SF32 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 110 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 structural protein#PC00211 HUMAN|HGNC=20561|UniProtKB=Q96CC6 Q96CC6 RHBDF1 PTHR45965:SF1 INACTIVE RHOMBOID PROTEIN INACTIVE RHOMBOID PROTEIN 1 signal transduction#GO:0007165;macromolecule localization#GO:0033036;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;protein secretion#GO:0009306;regulation of localization#GO:0032879;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of secretion#GO:0051046;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of protein transport#GO:0051223;signaling#GO:0023052;regulation of protein localization#GO:0032880;secretion by cell#GO:0032940;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;peptide transport#GO:0015833;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;protein localization#GO:0008104;localization#GO:0051179;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;establishment of protein localization to extracellular region#GO:0035592;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 serine protease#PC00203 HUMAN|HGNC=17785|UniProtKB=A6NGE7 A6NGE7 URAD PTHR43466:SF1 2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED 2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 decarboxylase#PC00089 HUMAN|HGNC=3506|UniProtKB=P49640 P49640 EVX1 PTHR46294:SF2 SEGMENTATION PROTEIN EVEN-SKIPPED HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4655|UniProtKB=P32780 P32780 GTF2H1 PTHR12856:SF0 TRANSCRIPTION INITIATION FACTOR IIH-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 1 DNA repair#GO:0006281;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;phosphorylation of RNA polymerase II C-terminal domain#GO:0070816;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 HUMAN|HGNC=16448|UniProtKB=Q7L266 Q7L266 ASRGL1 PTHR10188:SF37 L-ASPARAGINASE ISOASPARTYL PEPTIDASE/L-ASPARAGINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=11781|UniProtKB=O43548 O43548 TGM5 PTHR11590:SF38 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 5 transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular protein modification process#GO:0006464 transferase#PC00220 HUMAN|HGNC=1036|UniProtKB=Q9HBH7 Q9HBH7 BEX1 PTHR19430:SF3 PROTEIN BEX1-RELATED PROTEIN BEX1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16969|UniProtKB=Q92598 Q92598 HSPH1 PTHR45639:SF2 HSC70CB, ISOFORM G-RELATED HEAT SHOCK PROTEIN 105 KDA cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26111|UniProtKB=Q0P651 Q0P651 ABHD18 PTHR13617:SF14 PROTEIN ABHD18 PROTEIN ABHD18 HUMAN|HGNC=1592|UniProtKB=P51959 P51959 CCNG1 PTHR10177:SF59 CYCLINS CYCLIN-G1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin G#P04662;p53 pathway feedback loops 2#P04398>CYCLIN G#G04715;p53 pathway#P00059>Cyclin G#G04689 HUMAN|HGNC=8717|UniProtKB=Q9Y5F7 Q9Y5F7 PCDHGC4 PTHR24028:SF272 CADHERIN-87A PROTOCADHERIN GAMMA-C4 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=19426|UniProtKB=Q8TEX9 Q8TEX9 IPO4 PTHR10527:SF6 IMPORTIN BETA IMPORTIN-4 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=17272|UniProtKB=Q9HC77 Q9HC77 CENPJ PTHR10331:SF23 T COMPLEX PROTEIN 10 CENTROMERE PROTEIN J cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;nitrogen compound transport#GO:0071705;centrosome duplication#GO:0051298;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;peptide transport#GO:0015833;microtubule organizing center organization#GO:0031023;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;centriole replication#GO:0007099;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=49193|UniProtKB=A0A0G2JMD5 A0A0G2JMD5 PRAMEF33 PTHR14224:SF28 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 10-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=14313|UniProtKB=Q8WYA0 Q8WYA0 IFT81 PTHR15614:SF2 INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=20457|UniProtKB=P50876 P50876 RNF144A PTHR11685:SF99 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF144A ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=20092|UniProtKB=Q6VMQ6 Q6VMQ6 ATF7IP PTHR23210:SF22 ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 1 transcription cofactor#PC00217 HUMAN|HGNC=23368|UniProtKB=Q9H7P6 Q9H7P6 MVB12B PTHR31547:SF1 MULTIVESICULAR BODY SUBUNIT 12B MULTIVESICULAR BODY SUBUNIT 12B regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;epidermal growth factor receptor signaling pathway#GO:0007173;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=43627|UniProtKB=A0A1W2PR75 A0A1W2PR75 SSU72P8 PTHR20383:SF12 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;mRNA 3'-end processing#GO:0031124;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;mRNA polyadenylation#GO:0006378;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;dephosphorylation#GO:0016311;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 protein phosphatase#PC00195 HUMAN|HGNC=30261|UniProtKB=Q8WXC3 Q8WXC3 PYDC1 PTHR10454:SF131 CASPASE CASPASE-14-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of cellular protein metabolic process#GO:0032270;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;positive regulation of cell death#GO:0010942;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=17625|UniProtKB=Q2M3X9 Q2M3X9 ZNF674 PTHR24381:SF125 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 674 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21446|UniProtKB=Q96S86 Q96S86 HAPLN3 PTHR22804:SF40 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 3 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=6583|UniProtKB=P41214 P41214 EIF2D PTHR12217:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 2D EUKARYOTIC TRANSLATION INITIATION FACTOR 2D nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 translation initiation factor#PC00224 HUMAN|HGNC=5526|UniProtKB=P01859 P01859 IGHG2 PTHR23266:SF353 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=24337|UniProtKB=Q9NS00 Q9NS00 C1GALT1 PTHR23033:SF13 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;galactosyltransferase activity#GO:0008378;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=35466|UniProtKB=Q495Y7 Q495Y7 SPDYE7P PTHR31156:SF26 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E1-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=23356|UniProtKB=Q5T0T0 Q5T0T0 MARCHF8 PTHR45981:SF4 LD02310P E3 UBIQUITIN-PROTEIN LIGASE MARCHF8 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;MHC protein binding#GO:0042287;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;immune response#GO:0006955;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;antigen processing and presentation#GO:0019882;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;immune system process#GO:0002376;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;late endosome membrane#GO:0031902;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=7165|UniProtKB=Q99542 Q99542 MMP19 PTHR10201:SF166 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-19 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=8957|UniProtKB=P37287 P37287 PIGA PTHR45871:SF3 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=21053|UniProtKB=Q5TF39 Q5TF39 MFSD4B PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144 transporter#PC00227 HUMAN|HGNC=29448|UniProtKB=Q9BY31 Q9BY31 ZNF717 PTHR24376:SF193 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 33B-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6605|UniProtKB=Q8NHL6 Q8NHL6 LILRB1 PTHR11738:SF165 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 1-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=17352|UniProtKB=Q9UH17 Q9UH17 APOBEC3B PTHR13857:SF39 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3A-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363 response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;RNA phosphodiester bond hydrolysis#GO:0090501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;defense response to virus#GO:0051607;demethylation#GO:0070988;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;transposition#GO:0032196;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;RNA-dependent DNA biosynthetic process#GO:0006278;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;nucleic acid phosphodiester bond hydrolysis#GO:0090305;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147 HUMAN|HGNC=53444|UniProtKB=E5RIL1 E5RIL1 UPK3BL2 PTHR15446:SF2 UROPLAKIN III UROPLAKIN-3B-LIKE PROTEIN 1-RELATED intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=16205|UniProtKB=Q9BQP7 Q9BQP7 MGME1 PTHR31340:SF3 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 HUMAN|HGNC=2518|UniProtKB=O60931 O60931 CTNS PTHR13131:SF5 CYSTINOSIN CYSTINOSIN inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;L-amino acid transport#GO:0015807;establishment of localization#GO:0051234;organic anion transport#GO:0015711;amino acid transport#GO:0006865;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 amino acid transporter#PC00046 HUMAN|HGNC=27297|UniProtKB=Q5VXM1 Q5VXM1 CDCP2 PTHR24251:SF29 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN 2 serine protease#PC00203 HUMAN|HGNC=16715|UniProtKB=Q9H8H2 Q9H8H2 DDX31 PTHR24031:SF89 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX31-RELATED cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribonucleoprotein complex biogenesis#GO:0022613 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=7167|UniProtKB=O60882 O60882 MMP20 PTHR10201:SF125 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-20 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 odontogenesis of dentin-containing tooth#GO:0042475;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;extracellular structure organization#GO:0043062;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;catabolic process#GO:0009056;metabolic process#GO:0008152 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=30528|UniProtKB=Q96DA6 Q96DA6 DNAJC19 PTHR12763:SF55 UNCHARACTERIZED MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM14 pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;ATPase activator activity#GO:0001671;enzyme regulator activity#GO:0030234;ATPase activity#GO:0016887 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=26990|UniProtKB=Q86WR6 Q86WR6 C17orf64 PTHR21765:SF1 SIMILAR TO CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1 (CHD-1) DUF4208 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=14869|UniProtKB=Q9BWW9 Q9BWW9 APOL5 PTHR14096:SF6 APOLIPOPROTEIN L APOLIPOPROTEIN L5 lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052 HUMAN|HGNC=14703|UniProtKB=Q9Y5P1 Q9Y5P1 OR51B2 PTHR26450:SF164 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B2 transmembrane signal receptor#PC00197 HUMAN|HGNC=18193|UniProtKB=Q9NY93 Q9NY93 DDX56 PTHR24031:SF96 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX56-RELATED intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=1782|UniProtKB=Q92772 Q92772 CDKL2 PTHR24056:SF241 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 2 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=707|UniProtKB=P59998 P59998 ARPC4 PTHR22629:SF0 ARP2/3 COMPLEX 20 KD SUBUNIT ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 4 actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 HUMAN|HGNC=10785|UniProtKB=P84103 P84103 SRSF3 PTHR23147:SF121 SERINE/ARGININE RICH SPLICING FACTOR SERINE/ARGININE-RICH SPLICING FACTOR 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=34440|UniProtKB=A6NLE4 A6NLE4 SMIM23 PTHR37865:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 23 SMALL INTEGRAL MEMBRANE PROTEIN 23 HUMAN|HGNC=11280|UniProtKB=Q13501 Q13501 SQSTM1 PTHR15090:SF0 SEQUESTOSOME 1-RELATED SEQUESTOSOME-1 K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;kinase binding#GO:0019900 macroautophagy#GO:0016236;endomembrane system organization#GO:0010256;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;vesicle organization#GO:0016050;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229 HUMAN|HGNC=20782|UniProtKB=Q6UX68 Q6UX68 XKR5 PTHR16024:SF15 XK-RELATED PROTEIN XK-RELATED PROTEIN 5 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=2867|UniProtKB=Q02127 Q02127 DHODH PTHR48109:SF4 DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;pyrimidine nucleobase metabolic process#GO:0006206;pyrimidine nucleotide biosynthetic process#GO:0006221;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 dehydrogenase#PC00092 De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydrooratate oxidase#P02927 HUMAN|HGNC=12669|UniProtKB=P21796 P21796 VDAC1 PTHR11743:SF13 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;inorganic anion transmembrane transporter activity#GO:0015103;channel activity#GO:0015267;transporter activity#GO:0005215 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 voltage-gated ion channel#PC00241 HUMAN|HGNC=5003|UniProtKB=Q9UGU5 Q9UGU5 HMGXB4 PTHR46584:SF1 HMG DOMAIN-CONTAINING PROTEIN 4 HMG DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=24965|UniProtKB=Q96AY2 Q96AY2 EME1 PTHR21077:SF7 EME1 PROTEIN CROSSOVER JUNCTION ENDONUCLEASE EME1 DNA repair#GO:0006281;nuclear division#GO:0000280;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;replication fork processing#GO:0031297;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;mitotic DNA integrity checkpoint#GO:0044774;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;reproduction#GO:0000003;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;intra-S DNA damage checkpoint#GO:0031573;mitotic cell cycle process#GO:1903047;meiotic chromosome separation#GO:0051307;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;cellular nitrogen compound biosynthetic process#GO:0044271;reciprocal meiotic recombination#GO:0007131;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;cell cycle phase#GO:0022403;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;macromolecule biosynthetic process#GO:0009059;mitotic DNA damage checkpoint#GO:0044773;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;negative regulation of mitotic cell cycle#GO:0045930;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;biological phase#GO:0044848;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA replication#GO:0006260;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=11945|UniProtKB=P19237 P19237 TNNI1 PTHR13738:SF9 TROPONIN I TROPONIN I, SLOW SKELETAL MUSCLE multicellular organismal process#GO:0032501;muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008 supramolecular complex#GO:0099080;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 non-motor actin binding protein#PC00165 HUMAN|HGNC=5043|UniProtKB=P31942 P31942 HNRNPH3 PTHR13976:SF36 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=34528|UniProtKB=Q96B49 Q96B49 TOMM6 PTHR15527:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM6 HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM6 HOMOLOG primary active transporter#PC00068 HUMAN|HGNC=18540|UniProtKB=Q8TCG5 Q8TCG5 CPT1C PTHR22589:SF55 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 1, BRAIN ISOFORM transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=4821|UniProtKB=O14929 O14929 HAT1 PTHR12046:SF0 HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;H4 histone acetyltransferase activity#GO:0010485;N-acyltransferase activity#GO:0016410 peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;histone H4 acetylation#GO:0043967;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=28887|UniProtKB=Q9Y2U8 Q9Y2U8 LEMD3 PTHR13428:SF10 INNER NUCLEAR MEMBRANE PROTEIN MAN1 LEM DOMAIN CONTAINING PROTEIN INNER NUCLEAR MEMBRANE PROTEIN MAN1 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;membrane organization#GO:0061024;response to growth factor#GO:0070848;negative regulation of cellular response to growth factor stimulus#GO:0090288;regulation of signaling#GO:0023051;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;BMP signaling pathway#GO:0030509;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;organelle organization#GO:0006996;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;negative regulation of signal transduction#GO:0009968;nuclear envelope organization#GO:0006998 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=18006|UniProtKB=Q9Y2I1 Q9Y2I1 NISCH PTHR15454:SF35 NISCHARIN RELATED NISCHARIN enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=14300|UniProtKB=Q96S65 Q96S65 CSRNP1 PTHR13580:SF10 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE/SERINE-RICH NUCLEAR PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=13722|UniProtKB=P61970 P61970 NUTF2 PTHR12612:SF33 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear pore central transport channel#GO:0044613;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=23576|UniProtKB=Q86VS8 Q86VS8 HOOK3 PTHR18947:SF38 HOOK PROTEINS PROTEIN HOOK HOMOLOG 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 membrane traffic protein#PC00150 HUMAN|HGNC=17860|UniProtKB=Q8NC51 Q8NC51 SERBP1 PTHR12299:SF29 HYALURONIC ACID-BINDING PROTEIN 4 PLASMINOGEN ACTIVATOR INHIBITOR 1 RNA-BINDING PROTEIN nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=20751|UniProtKB=Q8IZQ1 Q8IZQ1 WDFY3 PTHR46108:SF1 BLUE CHEESE WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=21495|UniProtKB=Q96FN5 Q96FN5 KIF12 PTHR24115:SF418 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF12 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=31745|UniProtKB=Q8WWR9 Q8WWR9 PPDPFL PTHR14572:SF1 PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR-LIKE PROTEIN HUMAN|HGNC=28912|UniProtKB=Q9Y484 Q9Y484 WDR45 PTHR11227:SF44 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 4 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;autophagy of nucleus#GO:0044804;autophagy#GO:0006914 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;whole membrane#GO:0098805 HUMAN|HGNC=28119|UniProtKB=Q4G0F5 Q4G0F5 VPS26B PTHR12233:SF5 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26B endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=6924|UniProtKB=Q15012 Q15012 LAPTM4A PTHR12479:SF5 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4A bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 HUMAN|HGNC=12262|UniProtKB=A0A1B0GX56 A0A1B0GX56 TRDV1 PTHR23267:SF467 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR DELTA VARIABLE 1 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=25495|UniProtKB=Q9NW82 Q9NW82 WDR70 PTHR16017:SF0 GASTRULATION DEFECTIVE PROTEIN 1-RELATED WD REPEAT-CONTAINING PROTEIN 70 DNA repair#GO:0006281;regulation of double-strand break repair#GO:2000779;regulation of protein modification process#GO:0031399;regulation of response to DNA damage stimulus#GO:2001020;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of chromatin organization#GO:1902275;histone ubiquitination#GO:0016574;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;histone modification#GO:0016570;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;DNA double-strand break processing#GO:0000729;protein modification process#GO:0036211;regulation of histone modification#GO:0031056;regulation of DNA repair#GO:0006282;organic cyclic compound metabolic process#GO:1901360;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=20512|UniProtKB=Q5PSV4 Q5PSV4 BRMS1L PTHR21964:SF16 BREAST CANCER METASTASIS-SUPPRESSOR 1 BREAST CANCER METASTASIS-SUPPRESSOR 1-LIKE PROTEIN histone deacetylase binding#GO:0042826;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;enzyme binding#GO:0019899;protein binding#GO:0005515;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 HUMAN|HGNC=1455|UniProtKB=P27797 P27797 CALR PTHR11073:SF16 CALRETICULIN AND CALNEXIN CALRETICULIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;protein folding#GO:0006457;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 chaperone#PC00072 HUMAN|HGNC=30988|UniProtKB=Q6ZN30 Q6ZN30 BNC2 PTHR15021:SF2 DISCONNECTED-RELATED ZINC FINGER PROTEIN BASONUCLIN-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=20315|UniProtKB=Q9H0Y0 Q9H0Y0 ATG10 PTHR14957:SF1 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10 transferase activity#GO:0016740;Atg12 transferase activity#GO:0019777;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;protein modification by small protein conjugation or removal#GO:0070647;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;process utilizing autophagic mechanism#GO:0061919;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;lipoprotein metabolic process#GO:0042157;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;protein modification by small protein conjugation#GO:0032446;autophagy#GO:0006914;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=1779|UniProtKB=P49336 P49336 CDK8 PTHR24056:SF243 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 8 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;nuclear lumen#GO:0031981 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=9910|UniProtKB=P38159 P38159 RBMX PTHR48034:SF18 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA-BINDING MOTIF PROTEIN, X CHROMOSOME positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;positive regulation of RNA metabolic process#GO:0051254;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=33228|UniProtKB=P0C7X5 P0C7X5 ZNF806 PTHR24377:SF848 IP01015P-RELATED ZINC FINGER PROTEIN 806 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4982|UniProtKB=P08397 P08397 HMBS PTHR11557:SF0 PORPHOBILINOGEN DEAMINASE PORPHOBILINOGEN DEAMINASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;porphyrin-containing compound metabolic process#GO:0006778;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;heme metabolic process#GO:0042168;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 deaminase#PC00088 Heme biosynthesis#P02746>Hydroxymethylbilane synthase#P02983 HUMAN|HGNC=19367|UniProtKB=O94988 O94988 FAM13A PTHR15904:SF18 FAM13 PROTEIN FAM13A HUMAN|HGNC=33762|UniProtKB=Q5W5W9 Q5W5W9 RESP18 PTHR17314:SF0 REGULATED ENDOCRINE SPECIFIC PROTEIN 18 REGULATED ENDOCRINE-SPECIFIC PROTEIN 18 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=6302|UniProtKB=Q9BQ31 Q9BQ31 KCNS3 PTHR11537:SF39 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY S MEMBER 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=3013|UniProtKB=Q14117 Q14117 DPYS PTHR11647:SF50 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 HUMAN|HGNC=21595|UniProtKB=Q9Y6P5 Q9Y6P5 SESN1 PTHR12474:SF3 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-1 cation binding#GO:0043169;amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;positive regulation of cellular metabolic process#GO:0031325;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cell communication#GO:0007154;regulation of macroautophagy#GO:0016241;response to organonitrogen compound#GO:0010243;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;process utilizing autophagic mechanism#GO:0061919;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;positive regulation of metabolic process#GO:0009893;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;TORC1 signaling#GO:0038202;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;regulation of autophagy#GO:0010506;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198 TORC2 complex#GO:0031932;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 peroxidase#PC00180 HUMAN|HGNC=3694|UniProtKB=P02679 P02679 FGG PTHR19143:SF338 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN GAMMA CHAIN extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Blood coagulation#P00011>Fibrinogen#P00406;Plasminogen activating cascade#P00050>Fibrin#P01253;Blood coagulation#P00011>Fibrin monomer#P00418;Blood coagulation#P00011>Fibrin polymer cross-linked#P00443 HUMAN|HGNC=12974|UniProtKB=O15541 O15541 RNF113A PTHR12930:SF2 ZINC FINGER PROTEIN 183 E3 UBIQUITIN-PROTEIN LIGASE RNF113A cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=9213|UniProtKB=P09086 P09086 POU2F2 PTHR11636:SF46 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=7763|UniProtKB=Q15784 Q15784 NEUROD2 PTHR19290:SF83 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=48953|UniProtKB=A4D0T7 A4D0T7 SMIM30 PTHR36878:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 30 SMALL INTEGRAL MEMBRANE PROTEIN 30 HUMAN|HGNC=52278|UniProtKB=A0A0J9YY54 A0A0J9YY54 TEX13D PTHR23111:SF28 ZINC FINGER PROTEIN TESTIS-EXPRESSED PROTEIN 13D HUMAN|HGNC=494|UniProtKB=Q12955 Q12955 ANK3 PTHR24133:SF34 FAMILY NOT NAMED ANKYRIN-3 ion channel binding#GO:0044325;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=25054|UniProtKB=Q8NBI3 Q8NBI3 DRAXIN PTHR28610:SF1 DRAXIN DRAXIN cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=2027|UniProtKB=P51801 P51801 CLCNKB PTHR45720:SF3 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN CLC-KB inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;chloride transport#GO:0006821;establishment of localization#GO:0051234;anion transport#GO:0006820;inorganic anion transport#GO:0015698;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=29831|UniProtKB=O95544 O95544 NADK PTHR20275:SF0 NAD KINASE NAD KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;NADP metabolic process#GO:0006739;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 nucleotide kinase#PC00172 HUMAN|HGNC=22942|UniProtKB=Q9UQP3 Q9UQP3 TNN PTHR19143:SF348 FIBRINOGEN/TENASCIN/ANGIOPOEITIN TENASCIN-N cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;growth#GO:0040007;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;developmental cell growth#GO:0048588;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;cell-substrate adhesion#GO:0031589;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cell-matrix adhesion#GO:0007160;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=6108|UniProtKB=Q9Y573 Q9Y573 IPP PTHR24412:SF35 KELCH PROTEIN ACTIN-BINDING PROTEIN IPP scaffold/adaptor protein#PC00226 HUMAN|HGNC=27337|UniProtKB=Q75V66 Q75V66 ANO5 PTHR12308:SF23 NGEP-RELATED ANOCTAMIN-5 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;chloride transport#GO:0006821;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;inorganic anion transport#GO:0015698;anion transmembrane transport#GO:0098656 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=381|UniProtKB=P15121 P15121 AKR1B1 PTHR11732:SF294 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=12306|UniProtKB=Q14669 Q14669 TRIP12 PTHR45670:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=23190|UniProtKB=Q9BT49 Q9BT49 THAP7 PTHR47502:SF1 THAP DOMAIN-CONTAINING PROTEIN 7 THAP DOMAIN-CONTAINING PROTEIN 7 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=29237|UniProtKB=Q9ULE0 Q9ULE0 WWC3 PTHR14791:SF25 BOMB/KIRA PROTEINS PROTEIN WWC3 HUMAN|HGNC=26856|UniProtKB=Q8N7X8 Q8N7X8 SIGLECL1 PTHR12035:SF113 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIGLEC FAMILY-LIKE PROTEIN 1 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=17009|UniProtKB=Q9H2D6 Q9H2D6 TRIOBP PTHR17271:SF10 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN TRIO AND F-ACTIN-BINDING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 regulation of cell morphogenesis involved in differentiation#GO:0010769;positive regulation of cell-substrate adhesion#GO:0010811;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;biological adhesion#GO:0022610;substrate adhesion-dependent cell spreading#GO:0034446;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;regulation of cell adhesion#GO:0030155;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of cell adhesion#GO:0045785;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=18373|UniProtKB=Q8TD17 Q8TD17 ZNF398 PTHR24381:SF269 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 398 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=33185|UniProtKB=A6NMT0 A6NMT0 DBX1 PTHR24331:SF6 DBX HOMEOBOX PROTEIN DBX1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=6690|UniProtKB=Q12912 Q12912 IRAG2 PTHR15352:SF3 LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1 INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29555|UniProtKB=Q9Y2G7 Q9Y2G7 ZFP30 PTHR24377:SF246 IP01015P-RELATED ZINC FINGER PROTEIN 30 HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10788|UniProtKB=Q13247 Q13247 SRSF6 PTHR23147:SF82 SERINE/ARGININE RICH SPLICING FACTOR SERINE/ARGININE-RICH SPLICING FACTOR 6 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=28785|UniProtKB=Q7Z6M4 Q7Z6M4 MTERF4 PTHR13068:SF203 CGI-12 PROTEIN-RELATED TRANSCRIPTION TERMINATION FACTOR 4, MITOCHONDRIAL organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12827|UniProtKB=Q9UBH6 Q9UBH6 XPR1 PTHR10783:SF4 XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;small molecule binding#GO:0036094;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;anion binding#GO:0043168;ion binding#GO:0043167;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215 cellular response to stimulus#GO:0051716;ion transport#GO:0006811;transport#GO:0006810;cell communication#GO:0007154;response to nutrient levels#GO:0031667;response to extracellular stimulus#GO:0009991;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cellular response to starvation#GO:0009267;response to stress#GO:0006950;establishment of localization#GO:0051234;cellular response to nutrient levels#GO:0031669;anion transport#GO:0006820;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;inorganic anion transport#GO:0015698;cellular response to extracellular stimulus#GO:0031668 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=32393|UniProtKB=Q6ZNR0 Q6ZNR0 TMEM91 PTHR14768:SF2 UPF0338 PROTEIN TRANSMEMBRANE PROTEIN 91 HUMAN|HGNC=26286|UniProtKB=Q5FYB0 Q5FYB0 ARSJ PTHR10342:SF69 ARYLSULFATASE ARYLSULFATASE J HUMAN|HGNC=29005|UniProtKB=O15016 O15016 TRIM66 PTHR45915:SF7 TRANSCRIPTION INTERMEDIARY FACTOR TRIPARTITE MOTIF-CONTAINING PROTEIN 66 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=2203|UniProtKB=P08572 P08572 COL4A2 PTHR24023:SF588 COLLAGEN ALPHA COLLAGEN ALPHA-2(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;basement membrane#GO:0005604;extracellular region#GO:0005576;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;supramolecular polymer#GO:0099081 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=24658|UniProtKB=Q9BRR8 Q9BRR8 GPATCH1 PTHR13384:SF19 G PATCH DOMAIN-CONTAINING PROTEIN 1 G PATCH DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=1977|UniProtKB=Q9UHD4 Q9UHD4 CIDEB PTHR12306:SF10 CELL DEATH ACTIVATOR CIDE CELL DEATH ACTIVATOR CIDE-B regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=2267|UniProtKB=P20674 P20674 COX5A PTHR14200:SF16 CYTOCHROME C OXIDASE POLYPEPTIDE CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;inorganic cation transmembrane transporter activity#GO:0022890 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;aerobic electron transport chain#GO:0019646;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277 oxidase#PC00175 HUMAN|HGNC=7020|UniProtKB=Q16820 Q16820 MEP1B PTHR10127:SF814 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING MEPRIN A SUBUNIT BETA hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153 HUMAN|HGNC=8182|UniProtKB=Q15619 Q15619 OR1C1 PTHR48001:SF114 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1C1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=26688|UniProtKB=Q8IYX3 Q8IYX3 CCDC116 PTHR36861:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 116 COILED-COIL DOMAIN-CONTAINING PROTEIN 116 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=20041|UniProtKB=Q9H9D4 Q9H9D4 ZNF408 PTHR23226:SF219 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 408 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20322|UniProtKB=Q96T25 Q96T25 ZIC5 PTHR19818:SF69 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=16808|UniProtKB=Q8IWV7 Q8IWV7 UBR1 PTHR21497:SF27 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR1 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=10078|UniProtKB=Q9H4A4 Q9H4A4 RNPEP PTHR45726:SF1 FAMILY NOT NAMED AMINOPEPTIDASE B HUMAN|HGNC=18258|UniProtKB=Q9HBM0 Q9HBM0 VEZT PTHR15989:SF5 VEZATIN VEZATIN HUMAN|HGNC=34073|UniProtKB=A8MVS5 A8MVS5 HIDE1 PTHR36859:SF1 PROTEIN HIDE1 PROTEIN HIDE1 HUMAN|HGNC=8685|UniProtKB=Q9Y5E9 Q9Y5E9 PCDHB14 PTHR24028:SF81 CADHERIN-87A PROTOCADHERIN BETA-14 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=28758|UniProtKB=Q14CZ7 Q14CZ7 FASTKD3 PTHR21228:SF9 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL HUMAN|HGNC=18130|UniProtKB=Q8IZU3 Q8IZU3 SYCP3 PTHR19368:SF12 XLR/SCP3/FAM9 SYNAPTONEMAL COMPLEX PROTEIN 3 male gamete generation#GO:0048232;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;spermatid differentiation#GO:0048515;cell differentiation#GO:0030154;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;meiotic cell cycle#GO:0051321;multicellular organism reproduction#GO:0032504;cellular component organization#GO:0016043;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;cell cycle#GO:0007049 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=8587|UniProtKB=P22234 P22234 PAICS PTHR43599:SF3 MULTIFUNCTIONAL PROTEIN ADE2 MULTIFUNCTIONAL PROTEIN ADE2 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=5951|UniProtKB=Q9BY67 Q9BY67 CADM1 PTHR45889:SF2 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 1 HUMAN|HGNC=3817|UniProtKB=Q12952 Q12952 FOXL1 PTHR11829:SF204 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=31102|UniProtKB=Q8WZ33 Q8WZ33 MAFIP PTHR19960:SF12 TEKTIN MAFF-INTERACTING PROTEIN-RELATED microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cilium movement involved in cell motility#GO:0060294;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=6279|UniProtKB=Q9NYG8 Q9NYG8 KCNK4 PTHR11003:SF30 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=16008|UniProtKB=Q9BYV2 Q9BYV2 TRIM54 PTHR24103:SF596 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 54 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=7679|UniProtKB=Q92597 Q92597 NDRG1 PTHR11034:SF18 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 serine protease#PC00203 HUMAN|HGNC=15756|UniProtKB=Q9H190 Q9H190 SDCBP2 PTHR12345:SF13 SYNTENIN RELATED SYNTENIN-2 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=34299|UniProtKB=Q68CR7 Q68CR7 LRRC66 PTHR24366:SF31 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH REPEAT-CONTAINING PROTEIN 66 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=37206|UniProtKB=A6NDZ8 A6NDZ8 MBD3L4 PTHR12396:SF6 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 3-LIKE 2-RELATED HUMAN|HGNC=9770|UniProtKB=Q15771 Q15771 RAB30 PTHR47977:SF42 LD21953P-RELATED RAS-RELATED PROTEIN RAB-30 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=4250|UniProtKB=P19440 P19440 GGT1 PTHR11686:SF56 GAMMA GLUTAMYL TRANSPEPTIDASE GLUTATHIONE HYDROLASE 1 PROENZYME-RELATED transferase activity, transferring acyl groups#GO:0016746;hydrolase activity#GO:0016787;transferase activity#GO:0016740;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of response to external stimulus#GO:0032101;sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;inflammatory response#GO:0006954;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of inflammatory response#GO:0050727;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;regulation of defense response#GO:0031347;biological regulation#GO:0065007;catabolic process#GO:0009056;regulation of immune system process#GO:0002682;organic substance catabolic process#GO:1901575;defense response#GO:0006952;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 protease#PC00190 HUMAN|HGNC=32033|UniProtKB=Q4V348 Q4V348 ZNF658B PTHR24376:SF198 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 658-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=603|UniProtKB=P04114 P04114 APOB PTHR13769:SF1 APOLIPOPROTEIN B APOLIPOPROTEIN B-100 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;protein binding#GO:0005515;lipid binding#GO:0008289;transporter activity#GO:0005215;signaling receptor binding#GO:0005102;lipid transporter activity#GO:0005319;cholesterol binding#GO:0015485 organic hydroxy compound transport#GO:0015850;lipid metabolic process#GO:0006629;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;nitrogen compound transport#GO:0071705;acylglycerol metabolic process#GO:0006639;lipid transport#GO:0006869;establishment of protein localization#GO:0045184;neutral lipid metabolic process#GO:0006638;amide transport#GO:0042886;organic substance transport#GO:0071702;glycerolipid metabolic process#GO:0046486;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;lipid localization#GO:0010876;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;triglyceride metabolic process#GO:0006641;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;peptide transport#GO:0015833;cholesterol homeostasis#GO:0042632;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cholesterol transport#GO:0030301;protein transport#GO:0015031;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;cellular lipid metabolic process#GO:0044255 cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576 apolipoprotein#PC00052 HUMAN|HGNC=29000|UniProtKB=O14523 O14523 C2CD2L PTHR21119:SF8 UNCHARACTERIZED PHOSPHOLIPID TRANSFER PROTEIN C2CD2L HUMAN|HGNC=13954|UniProtKB=O60814 O60814 H2BC12 PTHR23428:SF250 HISTONE H2B HISTONE H2B TYPE 1-K nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=9380|UniProtKB=P17612 P17612 PRKACA PTHR24353:SF82 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA protein kinase A binding#GO:0051018;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein kinase A regulatory subunit binding#GO:0034237;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;anion binding#GO:0043168;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;CCKR signaling map#P06959>PKA-Calpha/beta/gamma#P07099;Nicotine pharmacodynamics pathway#P06587>PRKACA#P06588;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Enkephalin release#P05913>PKA#P05972;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-c#P00707;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Endothelin signaling pathway#P00019>PKA#P00570 HUMAN|HGNC=10911|UniProtKB=P55011 P55011 SLC12A2 PTHR11827:SF58 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;sodium:chloride symporter activity#GO:0015378;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;nitrogen compound transport#GO:0071705;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;chloride transport#GO:0006821;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;regulation of cellular component size#GO:0032535;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725 secondary carrier transporter#PC00258 HUMAN|HGNC=21144|UniProtKB=Q9UL01 Q9UL01 DSE PTHR15532:SF3 FAMILY NOT NAMED DERMATAN-SULFATE EPIMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;proteoglycan metabolic process#GO:0006029;chondroitin sulfate metabolic process#GO:0030204;chondroitin sulfate proteoglycan metabolic process#GO:0050654;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 HUMAN|HGNC=18278|UniProtKB=Q9NS91 Q9NS91 RAD18 PTHR14134:SF2 E3 UBIQUITIN-PROTEIN LIGASE RAD18 E3 UBIQUITIN-PROTEIN LIGASE RAD18 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;response to UV#GO:0009411;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=13189|UniProtKB=P21754 P21754 ZP3 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 POM121 AND ZP3 FUSION PROTEIN-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;regulation of reproductive process#GO:2000241;cellular process#GO:0009987;multi-organism process#GO:0051704;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;regulation of multi-organism process#GO:0043900;sperm-egg recognition#GO:0035036;multi-organism reproductive process#GO:0044703;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609;acrosome reaction#GO:0007340 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=24746|UniProtKB=Q8N9V7 Q8N9V7 TOPAZ1 PTHR35671:SF1 PROTEIN TOPAZ1 PROTEIN TOPAZ1 germ cell development#GO:0007281;cellular developmental process#GO:0048869;male gamete generation#GO:0048232;cell division#GO:0051301;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;spermatid differentiation#GO:0048515;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;anatomical structure development#GO:0048856;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609 HUMAN|HGNC=15771|UniProtKB=Q96SM3 Q96SM3 CPXM1 PTHR11532:SF43 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE X1-RELATED hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190 HUMAN|HGNC=20932|UniProtKB=Q15054 Q15054 POLD3 PTHR17598:SF13 DNA POLYMERASE DELTA SUBUNIT 3 DNA POLYMERASE DELTA SUBUNIT 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;DNA polymerase activity#GO:0034061;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular response to abiotic stimulus#GO:0071214;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;cellular nitrogen compound biosynthetic process#GO:0044271;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to light stimulus#GO:0071482;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;response to UV#GO:0009411;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;cellular response to environmental stimulus#GO:0104004;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 pre-replicative complex#GO:0036387;intracellular membrane-bounded organelle#GO:0043231;epsilon DNA polymerase complex#GO:0008622;replisome#GO:0030894;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;replication fork#GO:0005657;membrane-enclosed lumen#GO:0031974;origin recognition complex#GO:0000808;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;DNA replication preinitiation complex#GO:0031261;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;CMG complex#GO:0071162;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 DNA metabolism protein#PC00009 HUMAN|HGNC=6770|UniProtKB=Q13485 Q13485 SMAD4 PTHR13703:SF45 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 4 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;ubiquitin protein ligase binding#GO:0031625;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;nucleobase-containing compound metabolic process#GO:0006139;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;response to BMP#GO:0071772;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;BMP signaling pathway#GO:0030509;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;response to growth factor#GO:0070848;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to growth factor stimulus#GO:0071363;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 MYO signaling pathway#P06215>MED#P06311;Wnt signaling pathway#P00057>Smad4#P01455;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;DPP signaling pathway#P06213>MED#P06279;DPP-SCW signaling pathway#P06212>MED#P06265;SCW signaling pathway#P06216>MED#P06323;Activin beta signaling pathway#P06210>MED#P06233;BMP/activin signaling pathway-drosophila#P06211>Co-Smad#P06254;TGF-beta signaling pathway#P00052>Co-Smads#P01276;GBB signaling pathway#P06214>MED#P06299;TGF-beta signaling pathway#P00052>RSmads#P01292;ALP23B signaling pathway#P06209>MED#P06221 HUMAN|HGNC=18547|UniProtKB=Q9NRR3 Q9NRR3 CDC42SE2 PTHR13502:SF4 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CDC42 SMALL EFFECTOR PROTEIN 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=16380|UniProtKB=Q13049 Q13049 TRIM32 PTHR25464:SF3 TRIPARTITE MOTIF-CONTAINING PROTEIN 2-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE TRIM32 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=20453|UniProtKB=Q9H2R5 Q9H2R5 KLK15 PTHR24271:SF60 KALLIKREIN-RELATED KALLIKREIN-15 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=18786|UniProtKB=Q14320 Q14320 FAM50A PTHR12722:SF2 XAP-5 PROTEIN-RELATED PROTEIN FAM50A cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=26064|UniProtKB=Q969Z3 Q969Z3 MTARC2 PTHR14237:SF27 MOLYBDOPTERIN COFACTOR SULFURASE MOSC MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 2 cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=12148|UniProtKB=A0A0A6YYJ7 A0A0A6YYJ7 TRAV8-3 PTHR19367:SF5 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-3 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=20258|UniProtKB=Q8TEB1 Q8TEB1 DCAF11 PTHR19847:SF7 DDB1- AND CUL4-ASSOCIATED FACTOR 11 DDB1- AND CUL4-ASSOCIATED FACTOR 11 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=25081|UniProtKB=Q8IYS4 Q8IYS4 C16orf71 PTHR35977:SF1 CHROMOSOME 16 OPEN READING FRAME 71 CHROMOSOME 16 OPEN READING FRAME 71 HUMAN|HGNC=6364|UniProtKB=P07288 P07288 KLK3 PTHR24271:SF73 KALLIKREIN-RELATED PROSTATE-SPECIFIC ANTIGEN blood circulation#GO:0008015;macromolecule metabolic process#GO:0043170;system process#GO:0003008;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;regulation of systemic arterial blood pressure#GO:0003073;circulatory system process#GO:0003013;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;regulation of blood pressure#GO:0008217;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=17300|UniProtKB=Q7Z7C8 Q7Z7C8 TAF8 PTHR46469:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription by RNA polymerase I#P00022>TAF-IB#P00650;General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription by RNA polymerase I#P00022>TAF-IC#P00649 HUMAN|HGNC=19860|UniProtKB=Q8NCU1 Q8NCU1 CCDC197 PTHR21683:SF12 UNCHARACTERIZED DUF4200 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=30866|UniProtKB=Q8IX04 Q8IX04 UEVLD PTHR23306:SF18 TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 3 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=29933|UniProtKB=Q86WI3 Q86WI3 NLRC5 PTHR24106:SF278 NACHT, LRR AND CARD DOMAINS-CONTAINING PROTEIN NLRC5 scaffold/adaptor protein#PC00226 HUMAN|HGNC=10441|UniProtKB=P62241 P62241 RPS8 PTHR10394:SF12 40S RIBOSOMAL PROTEIN S8 40S RIBOSOMAL PROTEIN S8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=4341|UniProtKB=P15104 P15104 GLUL PTHR20852:SF45 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968 HUMAN|HGNC=1066|UniProtKB=P35226 P35226 BMI1 PTHR10825:SF21 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB COMPLEX PROTEIN BMI-1 chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;histone ubiquitination#GO:0016574;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;histone H2A ubiquitination#GO:0033522;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 HUMAN|HGNC=2946|UniProtKB=Q9UFH2 Q9UFH2 DNAH17 PTHR10676:SF284 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN 17, AXONEMAL pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement#GO:0003341 supramolecular complex#GO:0099080;axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 HUMAN|HGNC=33110|UniProtKB=Q6ZMW2 Q6ZMW2 ZNF782 PTHR24376:SF207 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 594-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=24340|UniProtKB=Q5VZE5 Q5VZE5 NAA35 PTHR21373:SF0 GLUCOSE REPRESSIBLE PROTEIN MAK10 N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT acetyltransferase#PC00038 HUMAN|HGNC=7639|UniProtKB=Q99457 Q99457 NAP1L3 PTHR11875:SF38 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 3 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;organelle organization#GO:0006996;chromosome organization#GO:0051276;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=2764|UniProtKB=Q01523 Q01523 DEFA5 PTHR11876:SF6 ALPHA-DEFENSIN 1 DEFENSIN-5 response to external biotic stimulus#GO:0043207;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;antibacterial humoral response#GO:0019731;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;innate immune response#GO:0045087;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cellular response to biotic stimulus#GO:0071216;cellular process#GO:0009987;defense response to Gram-positive bacterium#GO:0050830;response to lipopolysaccharide#GO:0032496;defense response to Gram-negative bacterium#GO:0050829;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=26934|UniProtKB=Q9Y3C1 Q9Y3C1 NOP16 PTHR13243:SF1 HSPC111 PROTEIN-RELATED NUCLEOLAR PROTEIN 16 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5892|UniProtKB=A0A075B6J2 A0A075B6J2 IGLV2-33 PTHR23267:SF444 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 2-18-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=11989|UniProtKB=P11388 P11388 TOP2A PTHR10169:SF61 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2-ALPHA cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;M phase#GO:0000279;meiotic chromosome separation#GO:0051307;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;cell cycle phase#GO:0022403;negative regulation of cellular process#GO:0048523;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;mitotic cell cycle checkpoint#GO:0007093;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;mitotic DNA integrity checkpoint#GO:0044774;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;homologous recombination#GO:0035825;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 HUMAN|HGNC=21734|UniProtKB=Q969G2 Q969G2 LHX4 PTHR24208:SF116 LIM/HOMEOBOX PROTEIN LHX LIM/HOMEOBOX PROTEIN LHX4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=8761|UniProtKB=Q9BUL8 Q9BUL8 PDCD10 PTHR13250:SF1 TF-1 CELL APOPTOSIS RELATED PROTEIN-15 PROGRAMMED CELL DEATH PROTEIN 10 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;endomembrane system organization#GO:0010256;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;Golgi organization#GO:0007030;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=6653|UniProtKB=Q8TE12 Q8TE12 LMX1A PTHR24208:SF88 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=2962|UniProtKB=Q8NCM8 Q8NCM8 DYNC2H1 PTHR10676:SF352 DYNEIN HEAVY CHAIN FAMILY PROTEIN CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1 pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;intraciliary retrograde transport#GO:0035721;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;cytoplasmic dynein complex#GO:0005868;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=10816|UniProtKB=P05408 P05408 SCG5 PTHR12738:SF0 NEUROENDOCRINE PROTEIN 7B2 NEUROENDOCRINE PROTEIN 7B2 molecular function regulator#GO:0098772;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234 regulation of cell communication#GO:0010646;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;regulation of secretion by cell#GO:1903530;cell communication#GO:0007154;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;localization#GO:0051179;regulation of biological process#GO:0050789;hormone secretion#GO:0046879;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;regulation of hormone secretion#GO:0046883;biological regulation#GO:0065007;signal release#GO:0023061;hormone transport#GO:0009914;cell-cell signaling#GO:0007267;signaling#GO:0023052;export from cell#GO:0140352;secretion by cell#GO:0032940 chaperone#PC00072 HUMAN|HGNC=2605|UniProtKB=Q02318 Q02318 CYP27A1 PTHR24291:SF6 CYTOCHROME P450 FAMILY 4 STEROL 26-HYDROXYLASE, MITOCHONDRIAL steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;cellular alcohol metabolic process#GO:0044107;alcohol biosynthetic process#GO:0046165;cholesterol metabolic process#GO:0008203;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;secondary alcohol metabolic process#GO:1902652;small molecule biosynthetic process#GO:0044283;steroid biosynthetic process#GO:0006694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177 Vitamin D metabolism and pathway#P04396>1alpha-Hydroxylase#P04603 HUMAN|HGNC=14560|UniProtKB=Q9UBI4 Q9UBI4 STOML1 PTHR10264:SF19 BAND 7 PROTEIN-RELATED STOMATIN-LIKE PROTEIN 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=26423|UniProtKB=Q86XE0 Q86XE0 SNX32 PTHR45850:SF3 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-32 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3575|UniProtKB=O95864 O95864 FADS2 PTHR19353:SF12 FATTY ACID DESATURASE 2 ACYL-COA 6-DESATURASE HUMAN|HGNC=20099|UniProtKB=Q8WUH1 Q8WUH1 CHURC1 PTHR31931:SF2 PROTEIN CHURCHILL PROTEIN CHURCHILL HUMAN|HGNC=32394|UniProtKB=A8MU46 A8MU46 SMTNL1 PTHR23167:SF45 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED SMOOTHELIN-LIKE PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856 HUMAN|HGNC=25725|UniProtKB=Q8IWA0 Q8IWA0 WDR75 PTHR44215:SF1 WD REPEAT-CONTAINING PROTEIN 75 WD REPEAT-CONTAINING PROTEIN 75 HUMAN|HGNC=10719|UniProtKB=Q13228 Q13228 SELENBP1 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 HUMAN|HGNC=24497|UniProtKB=Q6ZRI6 Q6ZRI6 C15orf39 PTHR28422:SF1 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 39 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 39 HUMAN|HGNC=18669|UniProtKB=Q8N3R9 Q8N3R9 MPP5 PTHR23122:SF14 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 5 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18055|UniProtKB=Q86YW7 Q86YW7 GPHB5 PTHR11515:SF14 GLYCOPROTEIN HORMONE BETA CHAIN GLYCOPROTEIN HORMONE BETA-5 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular#GO:0005622 peptide hormone#PC00179 HUMAN|HGNC=21874|UniProtKB=Q96ME1 Q96ME1 FBXL18 PTHR16134:SF19 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX/LRR-REPEAT PROTEIN 18 HUMAN|HGNC=15296|UniProtKB=Q8NGG2 Q8NGG2 OR5T2 PTHR24247:SF119 5-HYDROXYTRYPTAMINE RECEPTOR OLFACTORY RECEPTOR 5T2 cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=14927|UniProtKB=Q9BZW7 Q9BZW7 TSGA10 PTHR23159:SF14 CENTROSOMAL PROTEIN 2 TESTIS-SPECIFIC GENE 10 PROTEIN chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=8788|UniProtKB=O43924 O43924 PDE6D PTHR12976:SF0 RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE DELTA-SUBUNIT RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT DELTA cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phosphodiesterase#PC00185 HUMAN|HGNC=6593|UniProtKB=P48742 P48742 LHX1 PTHR24208:SF106 LIM/HOMEOBOX PROTEIN LHX LIM/HOMEOBOX PROTEIN LHX1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=28759|UniProtKB=Q9H5J8 Q9H5J8 TAF1D PTHR14562:SF3 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT D TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT D membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=10521|UniProtKB=P10523 P10523 SAG PTHR11792:SF15 ARRESTIN S-ARRESTIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;receptor internalization#GO:0031623;membrane organization#GO:0061024;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;endocytosis#GO:0006897;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;G protein-coupled receptor signaling pathway#GO:0007186 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>beta-arrestin#P01456;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>beta-arrestin#P00757 HUMAN|HGNC=29288|UniProtKB=A2RU67 A2RU67 FAM234B PTHR21419:SF25 FAMILY NOT NAMED PROTEIN FAM234B HUMAN|HGNC=9194|UniProtKB=P62487 P62487 POLR2G PTHR12709:SF4 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=9160|UniProtKB=P11086 P11086 PNMT PTHR10867:SF18 NNMT/PNMT/TEMT FAMILY MEMBER PHENYLETHANOLAMINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 HUMAN|HGNC=9907|UniProtKB=P29558 P29558 RBMS1 PTHR24012:SF702 RNA BINDING PROTEIN RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17341|UniProtKB=Q96Q11 Q96Q11 TRNT1 PTHR46173:SF1 CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL RNA processing factor#PC00147 HUMAN|HGNC=3388|UniProtKB=P54764 P54764 EPHA4 PTHR24416:SF337 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 4 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=28109|UniProtKB=Q96BD8 Q96BD8 SKA1 PTHR28573:SF1 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cell division#GO:0051301;nuclear division#GO:0000280;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;chromosome, centromeric region#GO:0000775;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;intracellular#GO:0005622;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;condensed chromosome outer kinetochore#GO:0000940;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 HUMAN|HGNC=28483|UniProtKB=Q8NDZ6 Q8NDZ6 TMEM161B PTHR13624:SF3 RE42071P TRANSMEMBRANE PROTEIN 161B HUMAN|HGNC=9546|UniProtKB=P28065 P28065 PSMB9 PTHR11599:SF50 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-9 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 HUMAN|HGNC=21059|UniProtKB=Q15013 Q15013 MAD2L1BP PTHR15681:SF1 MAD2L1-BINDING PROTEIN MAD2L1-BINDING PROTEIN HUMAN|HGNC=16089|UniProtKB=O15173 O15173 PGRMC2 PTHR10281:SF24 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=29068|UniProtKB=O60303 O60303 KATNIP PTHR21534:SF0 UNCHARACTERIZED KATANIN-INTERACTING PROTEIN HUMAN|HGNC=4186|UniProtKB=P52951 P52951 GBX2 PTHR24334:SF3 HOMEOBOX PROTEIN GBX HOMEOBOX PROTEIN GBX-2 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 head development#GO:0060322;regulation of multicellular organismal process#GO:0051239;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;brain development#GO:0007420;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of developmental process#GO:0050793;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=30425|UniProtKB=Q9NQ36 Q9NQ36 SCUBE2 PTHR24046:SF3 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=6117|UniProtKB=P14316 P14316 IRF2 PTHR11949:SF22 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=18512|UniProtKB=Q53H82 Q53H82 LACTB2 PTHR23131:SF0 ENDORIBONUCLEASE LACTB2 ENDORIBONUCLEASE LACTB2 endoribonuclease#PC00094 HUMAN|HGNC=6337|UniProtKB=Q14953 Q14953 KIR2DS5 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=18317|UniProtKB=Q9BSH3 Q9BSH3 NICN1 PTHR31239:SF4 NICOLIN 1 NICOLIN-1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=24934|UniProtKB=Q9HCI5 Q9HCI5 MAGEE1 PTHR11736:SF9 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN E1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=30646|UniProtKB=Q7KZF4 Q7KZF4 SND1 PTHR12302:SF2 EBNA2 BINDING PROTEIN P100 STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25472|UniProtKB=Q8N4H0 Q8N4H0 SPATA6L PTHR16435:SF5 SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6 SPERMATOGENESIS ASSOCIATED 6-LIKE PROTEIN HUMAN|HGNC=12559|UniProtKB=P07911 P07911 UMOD PTHR14002:SF40 ENDOGLIN/TGF-BETA RECEPTOR TYPE III UROMODULIN localization#GO:0051179;leukocyte migration#GO:0050900;granulocyte migration#GO:0097530;immune system process#GO:0002376;myeloid leukocyte migration#GO:0097529;neutrophil migration#GO:1990266;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 cell surface#GO:0009986;extracellular region#GO:0005576;plasma membrane region#GO:0098590;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=11720|UniProtKB=O75443 O75443 TECTA PTHR46160:SF3 ALPHA-TECTORIN-RELATED ALPHA-TECTORIN HUMAN|HGNC=5541|UniProtKB=P01871 P01871 IGHM PTHR23266:SF120 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY CONSTANT MU protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 B cell activation#P00010>mIgM#P00389 HUMAN|HGNC=8222|UniProtKB=Q8NH06 Q8NH06 OR1P1 PTHR48001:SF42 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1P1 transmembrane signal receptor#PC00197 HUMAN|HGNC=16035|UniProtKB=Q7RTU9 Q7RTU9 STRC PTHR23412:SF14 STEREOCILIN RELATED STEREOCILIN-RELATED cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;biological adhesion#GO:0022610 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;intracellular organelle#GO:0043229;stereocilium#GO:0032420;non-membrane-bounded organelle#GO:0043228;cell surface#GO:0009986;stereocilium bundle#GO:0032421;kinocilium#GO:0060091;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;non-motile cilium#GO:0097730;cluster of actin-based cell projections#GO:0098862;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=29350|UniProtKB=Q9H0B3 Q9H0B3 IQCN PTHR22590:SF2 UNCHARACTERIZED IQ DOMAIN-CONTAINING PROTEIN N HUMAN|HGNC=18856|UniProtKB=Q96BA8 Q96BA8 CREB3L1 PTHR46004:SF1 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 HUMAN|HGNC=14851|UniProtKB=Q8NH59 Q8NH59 OR51Q1 PTHR26450:SF84 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51Q1 transmembrane signal receptor#PC00197 HUMAN|HGNC=31305|UniProtKB=A6NM76 A6NM76 OR6C76 PTHR26454:SF18 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C76 transmembrane signal receptor#PC00197 HUMAN|HGNC=7765|UniProtKB=P21359 P21359 NF1 PTHR10194:SF142 RAS GTPASE-ACTIVATING PROTEINS NEUROFIBROMIN GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 HUMAN|HGNC=17429|UniProtKB=Q9P2M7 Q9P2M7 CGN PTHR46349:SF4 CINGULIN-LIKE PROTEIN 1-RELATED CINGULIN HUMAN|HGNC=25019|UniProtKB=Q9Y547 Q9Y547 HSPB11 PTHR33906:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 25 HOMOLOG microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=25956|UniProtKB=Q96JG6 Q96JG6 VPS50 PTHR13258:SF0 UNCHARACTERIZED SYNDETIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=23489|UniProtKB=Q96DC8 Q96DC8 ECHDC3 PTHR43602:SF1 FAMILY NOT NAMED ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL HUMAN|HGNC=11708|UniProtKB=P48775 P48775 TDO2 PTHR10138:SF0 TRYPTOPHAN 2,3-DIOXYGENASE TRYPTOPHAN 2,3-DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;dioxygenase activity#GO:0051213;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;aromatic amino acid family metabolic process#GO:0009072;nucleoside phosphate metabolic process#GO:0006753;alpha-amino acid metabolic process#GO:1901605;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;cellular amino acid metabolic process#GO:0006520;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 oxygenase#PC00177 HUMAN|HGNC=26238|UniProtKB=Q8WVC6 Q8WVC6 DCAKD PTHR10695:SF46 DEPHOSPHO-COA KINASE-RELATED DEPHOSPHO-COA KINASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 kinase#PC00137 Coenzyme A biosynthesis#P02736>Dephospho-CoA kinase#P02884 HUMAN|HGNC=26222|UniProtKB=Q8WVX9 Q8WVX9 FAR1 PTHR11011:SF45 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;ribonucleotide metabolic process#GO:0009259;fatty acid derivative metabolic process#GO:1901568;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;cellular amide metabolic process#GO:0043603;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4910|UniProtKB=Q16665 Q16665 HIF1A PTHR23043:SF7 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA HYPOXIA-INDUCIBLE FACTOR 1-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;response to hypoxia#GO:0001666;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;response to oxygen levels#GO:0070482;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;response to decreased oxygen levels#GO:0036293;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular response to hypoxia#GO:0071456;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;cellular response to stress#GO:0033554;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 VEGF signaling pathway#P00056>HIF-1#P01401;Angiogenesis#P00005>HIF-1#P00214;Hypoxia response via HIF activation#P00030>HIF-1alpha#P00818 HUMAN|HGNC=8986|UniProtKB=P11309 P11309 PIM1 PTHR22984:SF29 SERINE/THREONINE-PROTEIN KINASE PIM SERINE/THREONINE-PROTEIN KINASE PIM-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=11528|UniProtKB=P29371 P29371 TACR3 PTHR46925:SF1 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED NEUROMEDIN-K RECEPTOR neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 regulation of cellular component movement#GO:0051270;regulation of microtubule-based process#GO:0032886;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;microtubule-based movement#GO:0007018;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;regulation of localization#GO:0032879;sperm motility#GO:0097722;cell motility#GO:0048870;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;cilium movement involved in cell motility#GO:0060294;positive regulation of cellular component movement#GO:0051272;cilium movement#GO:0003341;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;cilium-dependent cell motility#GO:0060285;reproduction#GO:0000003;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;positive regulation of biological process#GO:0048518;locomotion#GO:0040011 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;B axonemal microtubule#GO:0097650;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=13069|UniProtKB=Q9NSD4 Q9NSD4 ZNF275 PTHR23226:SF193 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 275 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13961|UniProtKB=P35410 P35410 MAS1L PTHR11334:SF22 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MRG-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=20993|UniProtKB=Q9H446 Q9H446 RWDD1 PTHR12292:SF2 RWD DOMAIN-CONTAINING PROTEIN RWD DOMAIN-CONTAINING PROTEIN 1 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;polysome#GO:0005844;protein-containing complex#GO:0032991 HUMAN|HGNC=14653|UniProtKB=Q9HBI1 Q9HBI1 PARVB PTHR12114:SF7 PARVIN BETA-PARVIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;actin cytoskeleton reorganization#GO:0031532;cell morphogenesis involved in differentiation#GO:0000904;developmental process#GO:0032502;biological adhesion#GO:0022610;substrate adhesion-dependent cell spreading#GO:0034446;cell morphogenesis#GO:0000902;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;plasma membrane bounded cell projection assembly#GO:0120031 anchoring junction#GO:0070161;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;lamellipodium#GO:0030027;focal adhesion#GO:0005925;plasma membrane region#GO:0098590;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Parvin#P00945 HUMAN|HGNC=4526|UniProtKB=O95800 O95800 GPR75 PTHR24228:SF55 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTOR 75-RELATED signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;C-C chemokine binding#GO:0019957;binding#GO:0005488;peptide binding#GO:0042277;cytokine binding#GO:0019955;amide binding#GO:0033218;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;chemokine binding#GO:0019956;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|Ensembl=ENSG00000278646|UniProtKB=A0A087WWU0 A0A087WWU0 ENSG00000278646 PTHR32157:SF5 GENE 6268-RELATED CANCER/TESTIS ANTIGEN 47B HUMAN|HGNC=8207|UniProtKB=O60431 O60431 OR1I1 PTHR48001:SF53 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1I1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=1873|UniProtKB=Q9UEE9 Q9UEE9 CFDP1 PTHR23227:SF45 BUCENTAUR RELATED CRANIOFACIAL DEVELOPMENT PROTEIN 1 HUMAN|HGNC=24892|UniProtKB=Q6P4E1 Q6P4E1 GOLM2 PTHR15896:SF7 GOLGI PHOSPHOPROTEIN 2/GP73-RELATED PROTEIN GOLM2 HUMAN|HGNC=23044|UniProtKB=Q8WY41 Q8WY41 NANOS1 PTHR12887:SF6 NANOS PROTEIN NANOS HOMOLOG 1 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;reproductive process#GO:0022414;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;peptide metabolic process#GO:0006518;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;biosynthetic process#GO:0009058;translation#GO:0006412;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;multi-organism process#GO:0051704;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=11431|UniProtKB=O14662 O14662 STX16 PTHR19957:SF83 SYNTAXIN SYNTAXIN-16 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 HUMAN|HGNC=30385|UniProtKB=Q969E2 Q969E2 SCAMP4 PTHR10687:SF11 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 4 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 HUMAN|HGNC=15956|UniProtKB=Q96QE2 Q96QE2 SLC2A13 PTHR48020:SF12 PROTON MYO-INOSITOL COTRANSPORTER PROTON MYO-INOSITOL COTRANSPORTER transporter#PC00227 HUMAN|HGNC=17966|UniProtKB=Q9Y592 Q9Y592 CEP83 PTHR23170:SF2 NY-REN-58 ANTIGEN CENTROSOMAL PROTEIN OF 83 KDA HUMAN|HGNC=8947|UniProtKB=P19957 P19957 PI3 PTHR19441:SF30 WHEY ACDIC PROTEIN WAP ELAFIN serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antibacterial humoral response#GO:0019731;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=14454|UniProtKB=Q9UN88 Q9UN88 GABRQ PTHR18945:SF579 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT THETA signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;system process#GO:0003008;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=5930|UniProtKB=A0A075B6I9 A0A075B6I9 IGLV7-46 PTHR23267:SF464 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 7-46 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=21789|UniProtKB=Q9UG22 Q9UG22 GIMAP2 PTHR10903:SF7 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=8849|UniProtKB=O75879 O75879 GATB PTHR11659:SF0 GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;mitochondrial translation#GO:0032543;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 ligase#PC00142 HUMAN|HGNC=14428|UniProtKB=Q9H2T7 Q9H2T7 RANBP17 PTHR12596:SF8 EXPORTIN 4,7-RELATED RAN-BINDING PROTEIN 17 transporter activity#GO:0005215 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;nuclear transport#GO:0051169 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|Ensembl=ENSG00000283439|UniProtKB=A0A1B0GUW6 A0A1B0GUW6 SPEM3 PTHR34834:SF3 SPERMATID MATURATION PROTEIN 1 SPEM1 DOMAIN-CONTAINING PROTEIN male gamete generation#GO:0048232;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;microtubule-based movement#GO:0007018;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;cilium movement involved in cell motility#GO:0060294;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;spermatogenesis#GO:0007283;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;multicellular organism development#GO:0007275;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;multi-organism process#GO:0051704;cilium movement#GO:0003341;localization#GO:0051179;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;cilium-dependent cell motility#GO:0060285;reproduction#GO:0000003;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=19408|UniProtKB=Q86UE6 Q86UE6 LRRTM1 PTHR24373:SF290 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 1 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=5901|UniProtKB=A0A075B6K0 A0A075B6K0 IGLV3-16 PTHR23267:SF471 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-16 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=1074|UniProtKB=P18075 P18075 BMP7 PTHR11848:SF135 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 7 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP6/7#P06752;Gonadotropin-releasing hormone receptor pathway#P06664>BMP7#G06901;Gonadotropin-releasing hormone receptor pathway#P06664>BMP7#G06687;TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=7370|UniProtKB=Q8N5Y2 Q8N5Y2 MSL3 PTHR10880:SF36 MORTALITY FACTOR 4-LIKE PROTEIN MALE-SPECIFIC LETHAL 3 HOMOLOG negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;histone H4 acetylation#GO:0043967;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;peptidyl-lysine acetylation#GO:0018394;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;histone H4-K16 acetylation#GO:0043984;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=25968|UniProtKB=Q9NXL2 Q9NXL2 ARHGEF38 PTHR22834:SF17 NUCLEAR FUSION PROTEIN FUS2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 38 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 HUMAN|HGNC=8978|UniProtKB=P48736 P48736 PIK3CG PTHR10048:SF34 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;phosphatidylinositol-mediated signaling#GO:0048015;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;phosphatidylinositol 3-kinase signaling#GO:0014065;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;inositol lipid-mediated signaling#GO:0048017;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477;locomotion#GO:0040011;phosphatidylinositol phosphorylation#GO:0046854 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;Endothelin signaling pathway#P00019>PI3K#P00577;Integrin signalling pathway#P00034>PI3K#P00936;Angiogenesis#P00005>PI3K#P00236;B cell activation#P00010>PI3K#P00391;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;p53 pathway#P00059>PI3K#P04609;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900 HUMAN|HGNC=49544|UniProtKB=A0A1B0GVM6 A0A1B0GVM6 C11orf97 PTHR38326:SF1 CHROMOSOME 11 OPEN READING FRAME 97 CHROMOSOME 11 OPEN READING FRAME 97 ciliary transition fiber#GO:0097539;protein-containing complex#GO:0032991;ciliary base#GO:0097546;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 HUMAN|HGNC=20991|UniProtKB=Q8NB25 Q8NB25 FAM184A PTHR18870:SF7 PROTEIN TAG-278-RELATED PROTEIN FAM184A HUMAN|HGNC=44448|UniProtKB=D6RJB6 D6RJB6 USP17L20 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=18536|UniProtKB=Q8TDG4 Q8TDG4 HELQ PTHR24031:SF357 RNA HELICASE HELICASE POLQ-LIKE intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29646|UniProtKB=Q8TBR7 Q8TBR7 TLCD3A PTHR13439:SF20 CT120 PROTEIN TLC DOMAIN-CONTAINING PROTEIN 3A biological regulation#GO:0065007;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=2685|UniProtKB=Q92904 Q92904 DAZL PTHR11176:SF4 BOULE-RELATED DELETED IN AZOOSPERMIA-LIKE RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of translational initiation#GO:0045948;gene expression#GO:0010467;regulation of translational initiation#GO:0006446;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;translational initiation#GO:0006413;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=8499|UniProtKB=P19652 P19652 ORM2 PTHR11967:SF3 ALPHA-1-ACID GLYCOPROTEIN ALPHA-1-ACID GLYCOPROTEIN 2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=20771|UniProtKB=P68371 P68371 TUBB4B PTHR11588:SF247 TUBULIN TUBULIN BETA-4B CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 HUMAN|HGNC=10414|UniProtKB=P62854 P62854 RPS26 PTHR12538:SF7 40S RIBOSOMAL PROTEIN S26 40S RIBOSOMAL PROTEIN S26-RELATED structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;small ribosomal subunit#GO:0015935;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=5224|UniProtKB=Q00613 Q00613 HSF1 PTHR10015:SF274 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 1 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=37706|UniProtKB=P0CG00 P0CG00 ZSCAN5DP PTHR23226:SF138 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 5A-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=18569|UniProtKB=Q8IUE0 Q8IUE0 TGIF2LY PTHR11850:SF205 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF2LX-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=10345|UniProtKB=P18077 P18077 RPL35A PTHR10902:SF30 60S RIBOSOMAL PROTEIN L35A 60S RIBOSOMAL PROTEIN L35A structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=13906|UniProtKB=Q14582 Q14582 MXD4 PTHR11969:SF4 MAX DIMERIZATION, MAD MAX DIMERIZATION PROTEIN 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=1119|UniProtKB=Q10589 Q10589 BST2 PTHR15190:SF1 BONE MARROW STROMAL ANTIGEN 2 BONE MARROW STROMAL ANTIGEN 2 metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;immune response#GO:0006955;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252 cytoplasm#GO:0005737;cell surface#GO:0009986;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=9658|UniProtKB=P29350 P29350 PTPN6 PTHR46257:SF4 TYROSINE-PROTEIN PHOSPHATASE CORKSCREW TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6 protein phosphatase#PC00195 B cell activation#P00010>SHP-1#P00378;FGF signaling pathway#P00021>SHP2#P00647;Angiogenesis#P00005>SHP2#P00181;Interferon-gamma signaling pathway#P00035>PTP#P00960 HUMAN|HGNC=31953|UniProtKB=A8MZ59 A8MZ59 LEUTX PTHR45793:SF18 HOMEOBOX PROTEIN PAIRED-LIKE HOMEODOMAIN TRANSCRIPTION FACTOR LEUTX cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=6325|UniProtKB=O60282 O60282 KIF5C PTHR24115:SF380 KINESIN-RELATED KINESIN HEAVY CHAIN ISOFORM 5C pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;ATP-dependent microtubule motor activity, plus-end-directed#GO:0008574;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 neuron projection guidance#GO:0097485;microtubule-based protein transport#GO:0099118;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;axonogenesis#GO:0007409;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;protein localization to synapse#GO:0035418;cellular component organization#GO:0016043;peptide transport#GO:0015833;transport along microtubule#GO:0010970;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;taxis#GO:0042330;receptor localization to synapse#GO:0097120;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;developmental process#GO:0032502;transport#GO:0006810;cell projection morphogenesis#GO:0048858;amide transport#GO:0042886;axo-dendritic transport#GO:0008088;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;axon guidance#GO:0007411;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;synaptic vesicle transport#GO:0048489;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cell morphogenesis involved in differentiation#GO:0000904;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;microtubule-based transport#GO:0099111;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;microtubule-based process#GO:0007017;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;generation of neurons#GO:0048699 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=34004|UniProtKB=A6NF01 A6NF01 POM121B PTHR23193:SF5 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR ENVELOPE PORE MEMBRANE PROTEIN POM 121C-RELATED signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=15437|UniProtKB=Q9NZP0 Q9NZP0 OR6C3 PTHR26454:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=32309|UniProtKB=Q8N7F7 Q8N7F7 UBL4B PTHR47905:SF1 UBIQUITIN-LIKE PROTEIN 4B UBIQUITIN-LIKE PROTEIN 4B HUMAN|HGNC=19217|UniProtKB=Q6YHU6 Q6YHU6 THADA PTHR14387:SF7 THADA/DEATH RECEPTOR INTERACTING PROTEIN THYROID ADENOMA-ASSOCIATED PROTEIN cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6253|UniProtKB=Q9UQ05 Q9UQ05 KCNH4 PTHR10217:SF630 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=21214|UniProtKB=Q96IZ2 Q96IZ2 ADTRP PTHR10989:SF17 ANDROGEN-INDUCED PROTEIN 1-RELATED ANDROGEN-DEPENDENT TFPI-REGULATING PROTEIN cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=4401|UniProtKB=O14775 O14775 GNB5 PTHR19850:SF36 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-5 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;dopamine receptor signaling pathway#GO:0007212;regulation of molecular function#GO:0065009;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;regulation of hydrolase activity#GO:0051336;signaling#GO:0023052;cell-cell signaling#GO:0007267;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;regulation of GTPase activity#GO:0043087;cellular response to organic substance#GO:0071310;positive regulation of GTPase activity#GO:0043547;positive regulation of catalytic activity#GO:0043085;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta5L#P00748;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;PI3 kinase pathway#P00048>Gbetagamma#P01188;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443 HUMAN|HGNC=37708|UniProtKB=A8MT19 A8MT19 RHPN2P1 PTHR23031:SF5 RHOPHILIN RHOPHILIN-2-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=23217|UniProtKB=Q9NS71 Q9NS71 GKN1 PTHR16483:SF1 GASTROKINE 1 GASTROKINE-1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell population proliferation#GO:0008283;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=8190|UniProtKB=P47887 P47887 OR1E2 PTHR48001:SF163 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1E2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=33517|UniProtKB=Q86W11 Q86W11 ZSCAN30 PTHR23226:SF128 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 30 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=12618|UniProtKB=O75604 O75604 USP2 PTHR21646:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=31828|UniProtKB=P63135 P63135 ERVK-7 PTHR41694:SF4 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 10 POL PROTEIN-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 viral or transposable element protein#PC00237 HUMAN|HGNC=29916|UniProtKB=Q9UHQ1 Q9UHQ1 NARF PTHR11615:SF124 NITRATE, FORMATE, IRON DEHYDROGENASE NUCLEAR PRELAMIN A RECOGNITION FACTOR protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular process#GO:0009987;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intermediate filament#GO:0005882;intracellular organelle lumen#GO:0070013;intermediate filament cytoskeleton#GO:0045111;cytosol#GO:0005829;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;nuclear periphery#GO:0034399;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 dehydrogenase#PC00092 HUMAN|HGNC=30290|UniProtKB=Q9NZQ0 Q9NZQ0 DNAJC27 PTHR24073:SF269 DRAB5-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 27 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 HUMAN|HGNC=18103|UniProtKB=Q8N688 Q8N688 DEFB123 PTHR15001:SF3 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 123 antimicrobial response protein#PC00051 HUMAN|HGNC=18328|UniProtKB=Q96NS1 Q96NS1 YPEL4 PTHR13848:SF17 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 4 HUMAN|HGNC=26107|UniProtKB=A5D8W1 A5D8W1 CFAP69 PTHR14716:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69 structural protein#PC00211 HUMAN|HGNC=271|UniProtKB=Q9UKK3 Q9UKK3 PARP4 PTHR46530:SF1 PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP4 PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP4 protein modifying enzyme#PC00260 FAS signaling pathway#P00020>PARP#P00600 HUMAN|HGNC=3285|UniProtKB=P23588 P23588 EIF4B PTHR23236:SF42 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4B nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ribonucleoprotein complex binding#GO:0043021;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;double-stranded RNA binding#GO:0003725 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 translation initiation factor#PC00224 HUMAN|HGNC=23792|UniProtKB=Q96BZ4 Q96BZ4 PLD4 PTHR10185:SF8 PHOSPHOLIPASE D - RELATED 5'-3' EXONUCLEASE PLD4 phospholipase#PC00186 HUMAN|HGNC=28924|UniProtKB=Q86Z20 Q86Z20 CCDC125 PTHR28616:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 125 COILED-COIL DOMAIN-CONTAINING PROTEIN 125 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;regulation of localization#GO:0032879;negative regulation of Ras protein signal transduction#GO:0046580;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;negative regulation of cellular component movement#GO:0051271;regulation of signal transduction#GO:0009966;negative regulation of small GTPase mediated signal transduction#GO:0051058;negative regulation of cell motility#GO:2000146;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of cellular component movement#GO:0051270;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;negative regulation of locomotion#GO:0040013;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;localization of cell#GO:0051674;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;regulation of small GTPase mediated signal transduction#GO:0051056;localization#GO:0051179;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of signal transduction#GO:0009968;locomotion#GO:0040011;regulation of Ras protein signal transduction#GO:0046578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=12474|UniProtKB=P51668 P51668 UBE2D1 PTHR24068:SF36 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=29508|UniProtKB=Q9ULH0 Q9ULH0 KIDINS220 PTHR24116:SF0 KINASE D-INTERACTING SUBSTRATE OF 220 KDA KINASE D-INTERACTING SUBSTRATE OF 220 KDA protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 HUMAN|HGNC=28482|UniProtKB=Q8WW35 Q8WW35 TCTEX1D2 PTHR21255:SF7 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN TCTEX1 DOMAIN-CONTAINING PROTEIN 2 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=14540|UniProtKB=Q9H4A3 Q9H4A3 WNK1 PTHR13902:SF46 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE/THREONINE-PROTEIN KINASE WNK1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;transferase activity, transferring phosphorus-containing groups#GO:0016772;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;transporter activity#GO:0005215;kinase activity#GO:0016301;channel activity#GO:0015267;protein kinase activity#GO:0004672;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;transferase activity#GO:0016740;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;protein serine/threonine kinase activity#GO:0004674;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;catalytic activity, acting on a protein#GO:0140096;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890 regulation of sodium ion transport#GO:0002028;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of transmembrane transport#GO:0034764;regulation of transmembrane transporter activity#GO:0022898;intracellular signal transduction#GO:0035556;regulation of transporter activity#GO:0032409;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of transport#GO:0051050;cell communication#GO:0007154;negative regulation of transport#GO:0051051;ion transmembrane transport#GO:0034220;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;regulation of ion transport#GO:0043269;positive regulation of ion transport#GO:0043270;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;ion homeostasis#GO:0050801;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;positive regulation of ion transmembrane transporter activity#GO:0032414;homeostatic process#GO:0042592;protein phosphorylation#GO:0006468;cellular process#GO:0009987;chemical homeostasis#GO:0048878;localization#GO:0051179;response to stimulus#GO:0050896;sodium ion transport#GO:0006814;positive regulation of transporter activity#GO:0032411;positive regulation of ion transmembrane transport#GO:0034767;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;sodium ion transmembrane transport#GO:0035725 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=18816|UniProtKB=Q6UWL6 Q6UWL6 KIRREL2 PTHR11640:SF51 NEPHRIN KIN OF IRRE-LIKE PROTEIN 2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=15514|UniProtKB=Q13492 Q13492 PICALM PTHR22951:SF16 CLATHRIN ASSEMBLY PROTEIN PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;establishment of organelle localization#GO:0051656;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;presynaptic membrane#GO:0042734;vesicle#GO:0031982;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=8890|UniProtKB=P20142 P20142 PGC PTHR13683:SF292 ASPARTYL PROTEASES GASTRICSIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 aspartic protease#PC00053 HUMAN|HGNC=17061|UniProtKB=Q9Y3D2 Q9Y3D2 MSRB2 PTHR10173:SF37 METHIONINE SULFOXIDE REDUCTASE METHIONINE-R-SULFOXIDE REDUCTASE B2, MITOCHONDRIAL oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=21463|UniProtKB=Q99551 Q99551 MTERF1 PTHR15437:SF2 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR 1, MITOCHONDRIAL nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 General transcription regulation#P00023>TTF2#P00661;Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 HUMAN|HGNC=15713|UniProtKB=Q9UJX4 Q9UJX4 ANAPC5 PTHR12830:SF9 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;protein catabolic process#GO:0030163;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;chromosome segregation#GO:0007059;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic sister chromatid segregation#GO:0033047;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;protein K11-linked ubiquitination#GO:0070979;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;protein modification by small protein conjugation or removal#GO:0070647;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;positive regulation of organelle organization#GO:0010638;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;mitotic cell cycle process#GO:1903047;positive regulation of cell cycle process#GO:0090068;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;positive regulation of mitotic nuclear division#GO:0045840;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;metaphase/anaphase transition of cell cycle#GO:0044784;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of mitotic cell cycle#GO:0007346 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 HUMAN|HGNC=15267|UniProtKB=Q8NGF7 Q8NGF7 OR5B17 PTHR48018:SF107 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5B17 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=1818|UniProtKB=P40199 P40199 CEACAM6 PTHR44337:SF20 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 6 HUMAN|HGNC=15774|UniProtKB=Q8WWY6 Q8WWY6 MBD3L1 PTHR12396:SF1 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 3-LIKE 1 HUMAN|HGNC=9906|UniProtKB=O43251 O43251 RBFOX2 PTHR15597:SF31 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;RNA processing#GO:0006396;gene expression#GO:0010467;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;multicellular organismal process#GO:0032501;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=16789|UniProtKB=Q9BZQ4 Q9BZQ4 NMNAT2 PTHR12039:SF18 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE/NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 2 adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 nucleotidyltransferase#PC00174 HUMAN|HGNC=25804|UniProtKB=Q8TBM7 Q8TBM7 TMEM254 PTHR34104:SF3 TRANSMEMBRANE PROTEIN 254 TRANSMEMBRANE PROTEIN 254 HUMAN|Gene=SPDL3_HUMAN|UniProtKB=A6NJR5 A6NJR5 - PTHR31156:SF26 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E1-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=12210|UniProtKB=A0A5B7 A0A5B7 TRBV29-1 PTHR23268:SF102 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 29-1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=15825|UniProtKB=Q9Y2N7 Q9Y2N7 HIF3A PTHR23043:SF18 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA HYPOXIA-INDUCIBLE FACTOR 3-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;response to hypoxia#GO:0001666;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;response to abiotic stimulus#GO:0009628;regulation of gene expression#GO:0010468;response to oxygen levels#GO:0070482;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;response to decreased oxygen levels#GO:0036293;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular response to hypoxia#GO:0071456;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;cellular response to stress#GO:0033554;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=13910|UniProtKB=Q5HYR2 Q5HYR2 DMRTC1B PTHR12322:SF117 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR C1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;reproductive process#GO:0022414;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;sex differentiation#GO:0007548;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;developmental process involved in reproduction#GO:0003006;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism reproduction#GO:0032504;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;multi-organism process#GO:0051704;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=2277|UniProtKB=P12074 P12074 COX6A1 PTHR11504:SF4 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT 6A1, MITOCHONDRIAL inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;molecular function regulator#GO:0098772;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;oxidoreductase activity#GO:0016491;enzyme regulator activity#GO:0030234 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;aerobic electron transport chain#GO:0019646;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277 oxidase#PC00175 HUMAN|HGNC=29631|UniProtKB=Q6UW68 Q6UW68 TMEM205 PTHR46916:SF2 TRANSMEMBRANE PROTEIN 205 TRANSMEMBRANE PROTEIN 205 HUMAN|HGNC=20757|UniProtKB=Q9H8W4 Q9H8W4 PLEKHF2 PTHR46280:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 HUMAN|HGNC=28360|UniProtKB=Q9BW61 Q9BW61 DDA1 PTHR31879:SF6 DET1- AND DDB1-ASSOCIATED PROTEIN 1 DET1- AND DDB1-ASSOCIATED PROTEIN 1 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;regulation of cellular protein catabolic process#GO:1903362;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 HUMAN|HGNC=4010|UniProtKB=P35637 P35637 FUS PTHR23238:SF5 RNA BINDING PROTEIN RNA-BINDING PROTEIN FUS transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=32281|UniProtKB=Q6ZN79 Q6ZN79 ZNF705A PTHR24381:SF303 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 705A-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20357|UniProtKB=Q9BUY7 Q9BUY7 EFCAB11 PTHR23050:SF354 CALCIUM BINDING PROTEIN EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 11 cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;molecular function regulator#GO:0098772;calcium ion binding#GO:0005509;ion binding#GO:0043167;enzyme regulator activity#GO:0030234 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 calmodulin-related#PC00061 HUMAN|HGNC=14963|UniProtKB=Q96P66 Q96P66 GPR101 PTHR24248:SF176 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 101-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 HUMAN|HGNC=27892|UniProtKB=Q1A5X7 Q1A5X7 WHAMMP3 PTHR23330:SF6 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED WASP HOMOLOG-ASSOCIATED PROTEIN WITH ACTIN, MEMBRANES AND MICROTUBULES-RELATED Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;small GTPase binding#GO:0031267;GTP-Rho binding#GO:0017049;Rho GTPase binding#GO:0017048 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;transport#GO:0006810;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;negative regulation of cell cycle#GO:0045786;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cell cycle arrest#GO:0007050;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;cell cycle#GO:0007049;positive regulation of cytoskeleton organization#GO:0051495;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 HUMAN|HGNC=19269|UniProtKB=Q8TAA1 Q8TAA1 RNASE11 PTHR11437:SF22 RIBONUCLEASE RIBONUCLEASE 11-RELATED HUMAN|HGNC=15717|UniProtKB=P57678 P57678 GEMIN4 PTHR15571:SF2 GEM-ASSOCIATED PROTEIN 4 GEM-ASSOCIATED PROTEIN 4 HUMAN|HGNC=26351|UniProtKB=Q8IXT1 Q8IXT1 DDIAS PTHR35537:SF1 DNA DAMAGE-INDUCIBLE APOPTOSIS SUPPRESSOR PROTEIN DDIAS DNA DAMAGE-INDUCED APOPTOSIS SUPPRESSOR PROTEIN negative regulation of biological process#GO:0048519;negative regulation of cell cycle#GO:0045786;nuclear division#GO:0000280;cell cycle process#GO:0022402;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cell cycle arrest#GO:0007050;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26574|UniProtKB=Q96LX7 Q96LX7 CCDC17 PTHR33820:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 COILED-COIL DOMAIN-CONTAINING PROTEIN 17 HUMAN|HGNC=2313|UniProtKB=P22792 P22792 CPN2 PTHR24373:SF271 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN CARBOXYPEPTIDASE N SUBUNIT 2 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=17195|UniProtKB=Q8NEB7 Q8NEB7 ACRBP PTHR21362:SF1 ACROSIN-BINDING PROTEIN ACROSIN-BINDING PROTEIN acrosomal vesicle#GO:0001669;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=708|UniProtKB=O15511 O15511 ARPC5 PTHR12644:SF1 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 5 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;localization of cell#GO:0051674;actin polymerization or depolymerization#GO:0008154;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Huntington disease#P00029>Arp2/3 complex#P00811 HUMAN|HGNC=17145|UniProtKB=O95295 O95295 SNAPIN PTHR31305:SF2 SNARE-ASSOCIATED PROTEIN SNAPIN SNARE-ASSOCIATED PROTEIN SNAPIN protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 lysosome organization#GO:0007040;vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;endosome to lysosome transport#GO:0008333;regulation of neurotransmitter secretion#GO:0046928;lysosomal transport#GO:0007041;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;lysosome localization#GO:0032418;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;vacuolar transport#GO:0007034;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of trans-synaptic signaling#GO:0099177;intracellular transport#GO:0046907;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;BLOC-1 complex#GO:0031083;cell junction#GO:0030054;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=29083|UniProtKB=O75121 O75121 MFAP3L PTHR14340:SF2 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 MICROFIBRILLAR-ASSOCIATED PROTEIN 3-LIKE cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=18056|UniProtKB=Q8IZX4 Q8IZX4 TAF1L PTHR13900:SF2 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1-LIKE molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription regulator activity#GO:0140110;RNA polymerase II general transcription initiation factor activity#GO:0016251;transcription factor binding#GO:0008134;binding#GO:0005488;TBP-class protein binding#GO:0017025 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=16276|UniProtKB=Q9C035 Q9C035 TRIM5 PTHR24103:SF416 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 5 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;protein homodimerization activity#GO:0042803;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;identical protein binding#GO:0042802;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;kinase binding#GO:0019900 regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;aromatic compound biosynthetic process#GO:0019438;positive regulation of autophagy#GO:0010508;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=8739|UniProtKB=Q9UKZ9 Q9UKZ9 PCOLCE2 PTHR24251:SF31 OVOCHYMASE-RELATED PROCOLLAGEN C-ENDOPEPTIDASE ENHANCER 2 serine protease#PC00203 HUMAN|HGNC=16964|UniProtKB=O00399 O00399 DCTN6 PTHR13072:SF0 DYNACTIN 6 DYNACTIN SUBUNIT 6 protein-containing complex binding#GO:0044877;binding#GO:0005488 mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156 HUMAN|HGNC=31992|UniProtKB=Q6P3W6 Q6P3W6 NBPF10 PTHR14199:SF35 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 10-RELATED HUMAN|HGNC=24343|UniProtKB=Q9P0U4 Q9P0U4 CXXC1 PTHR46174:SF1 CXXC-TYPE ZINC FINGER PROTEIN 1 CXXC-TYPE ZINC FINGER PROTEIN 1 HUMAN|HGNC=3317|UniProtKB=Q15723 Q15723 ELF2 PTHR11849:SF10 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=12638|UniProtKB=O14607 O14607 UTY PTHR14017:SF25 LYSINE-SPECIFIC DEMETHYLASE HISTONE DEMETHYLASE UTY cis-regulatory region sequence-specific DNA binding#GO:0000987;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;demethylase activity#GO:0032451;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;catalytic activity, acting on a protein#GO:0140096 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=20479|UniProtKB=Q8IUB3 Q8IUB3 WFDC10B PTHR19441:SF17 WHEY ACDIC PROTEIN WAP PROTEIN WFDC10B serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antibacterial humoral response#GO:0019731;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=20710|UniProtKB=Q9BTP6 Q9BTP6 ZBED2 PTHR35827:SF1 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 3 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=25629|UniProtKB=Q9NUU6 Q9NUU6 OTULINL PTHR33662:SF1 OTU DEUBIQUITINASE WITH LINEAR LINKAGE-SPECIFICITY A-RELATED INACTIVE UBIQUITIN THIOESTERASE OTULINL thiol-dependent ubiquitin-specific protease activity#GO:0004843;hydrolase activity#GO:0016787;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=26234|UniProtKB=Q96H55 Q96H55 MYO19 PTHR13140:SF289 MYOSIN UNCONVENTIONAL MYOSIN-XIX pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=49179|UniProtKB=A6NGN4 A6NGN4 PRAMEF25 PTHR14224:SF100 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 11-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=358|UniProtKB=O00170 O00170 AIP PTHR11242:SF3 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED AH RECEPTOR-INTERACTING PROTEIN chaperone#PC00072 HUMAN|HGNC=14583|UniProtKB=Q9H270 Q9H270 VPS11 PTHR23323:SF24 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG protein binding#GO:0005515;molecular adaptor activity#GO:0060090;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;endosome organization#GO:0007032;vacuole organization#GO:0007033;regulation of transport#GO:0051049;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;secretion#GO:0046903;vesicle organization#GO:0016050;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;export from cell#GO:0140352 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=28191|UniProtKB=Q9BSF0 Q9BSF0 C2orf88 PTHR36471:SF1 SMALL MEMBRANE A-KINASE ANCHOR PROTEIN SMALL MEMBRANE A-KINASE ANCHOR PROTEIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=6349|UniProtKB=Q13887 Q13887 KLF5 PTHR23235:SF82 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6998|UniProtKB=O15553 O15553 MEFV PTHR24103:SF606 E3 UBIQUITIN-PROTEIN LIGASE TRIM PYRIN ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=8031|UniProtKB=P04629 P04629 NTRK1 PTHR24416:SF370 TYROSINE-PROTEIN KINASE RECEPTOR HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to growth factor#GO:0070848;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein kinase B signaling#GO:0043491;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of protein kinase B signaling#GO:0051896;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=23090|UniProtKB=Q8N697 Q8N697 SLC15A4 PTHR11654:SF80 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;basic amino acid transmembrane transporter activity#GO:0015174;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;basic amino acid transport#GO:0015802;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812 transporter#PC00227 HUMAN|HGNC=1540|UniProtKB=P08185 P08185 SERPINA6 PTHR11461:SF34 SERINE PROTEASE INHIBITOR, SERPIN CORTICOSTEROID-BINDING GLOBULIN serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=18416|UniProtKB=Q9BVA6 Q9BVA6 FICD PTHR13504:SF34 FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145 PROTEIN ADENYLYLTRANSFERASE FICD HUMAN|HGNC=25714|UniProtKB=Q96ER9 Q96ER9 CCDC51 PTHR28624:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 51 MITOCHONDRIAL POTASSIUM CHANNEL HUMAN|HGNC=11791|UniProtKB=Q07283 Q07283 TCHH PTHR34855:SF1 TRICHOHYALIN TRICHOHYALIN cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;intermediate filament cytoskeleton organization#GO:0045104;supramolecular fiber organization#GO:0097435 HUMAN|HGNC=9691|UniProtKB=Q9NZH5 Q9NZH5 PTTG2 PTHR10418:SF8 SECURIN-3 SECURIN-2 negative regulation of sister chromatid segregation#GO:0033046;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;telophase#GO:0051326;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;M phase#GO:0000279;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of mitotic sister chromatid segregation#GO:0033047;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;negative regulation of cellular component organization#GO:0051129;meiosis I#GO:0007127;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;meiosis I cell cycle phase#GO:0098764;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;cellular component organization#GO:0016043;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;regulation of chromosome separation#GO:1905818;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;cell cycle phase#GO:0022403;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;negative regulation of chromosome separation#GO:1905819;meiotic nuclear division#GO:0140013;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;biological phase#GO:0044848;cell cycle#GO:0007049;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28332|UniProtKB=Q8WUD4 Q8WUD4 CCDC12 PTHR31551:SF1 PRE-MRNA-SPLICING FACTOR CWF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 12 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=20714|UniProtKB=Q969W1 Q969W1 ZDHHC16 PTHR12246:SF13 PALMITOYLTRANSFERASE ZDHHC16 PALMITOYLTRANSFERASE ZDHHC16 protein modifying enzyme#PC00260 HUMAN|HGNC=2732|UniProtKB=P30046 P30046 DDT PTHR11954:SF21 D-DOPACHROME DECARBOXYLASE D-DOPACHROME DECARBOXYLASE decarboxylase#PC00089 HUMAN|HGNC=28308|UniProtKB=Q6UXB0 Q6UXB0 FAM131A PTHR15736:SF4 PROTEIN FAM131B-RELATED PROTEIN FAM131A HUMAN|HGNC=32372|UniProtKB=A2RUT3 A2RUT3 TMEM89 PTHR37869:SF1 TRANSMEMBRANE PROTEIN 89 TRANSMEMBRANE PROTEIN 89 HUMAN|HGNC=10580|UniProtKB=Q9UN30 Q9UN30 SCML1 PTHR12247:SF128 POLYCOMB GROUP PROTEIN SEX COMB ON MIDLEG-LIKE PROTEIN 1 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=16523|UniProtKB=Q9H0T7 Q9H0T7 RAB17 PTHR24073:SF912 DRAB5-RELATED RAS-RELATED PROTEIN RAB-17 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle organization#GO:0016050;regulation of endocytosis#GO:0030100;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 HUMAN|HGNC=21111|UniProtKB=Q6AI39 Q6AI39 BICRAL PTHR15572:SF2 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 BRD4-INTERACTING CHROMATIN-REMODELING COMPLEX-ASSOCIATED PROTEIN-LIKE transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=24796|UniProtKB=Q6NY19 Q6NY19 KANK3 PTHR24168:SF23 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 3 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=10863|UniProtKB=Q16842 Q16842 ST3GAL2 PTHR46032:SF4 ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 2 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 transferase#PC00220 HUMAN|HGNC=22474|UniProtKB=Q9UHV7 Q9UHV7 MED13 PTHR48249:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=33795|UniProtKB=Q8N912 Q8N912 NRAC PTHR36868:SF1 NUTRITIONALLY-REGULATED ADIPOSE AND CARDIAC ENRICHED PROTEIN HOMOLOG NUTRITIONALLY-REGULATED ADIPOSE AND CARDIAC ENRICHED PROTEIN HOMOLOG HUMAN|HGNC=15840|UniProtKB=Q9UMN6 Q9UMN6 KMT2B PTHR45838:SF3 HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER HISTONE-LYSINE N-METHYLTRANSFERASE 2B N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;histone methylation#GO:0016571;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein alkylation#GO:0008213;protein methylation#GO:0006479;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone H3-K4 methylation#GO:0051568;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;histone lysine methylation#GO:0034968;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=5989|UniProtKB=O95256 O95256 IL18RAP PTHR11890:SF23 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-18 RECEPTOR ACCESSORY PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;cytokine binding#GO:0019955 response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 transmembrane signal receptor#PC00197 HUMAN|HGNC=30265|UniProtKB=Q6WKZ4 Q6WKZ4 RAB11FIP1 PTHR15746:SF22 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 1 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;regulated exocytosis#GO:0045055;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18194|UniProtKB=Q70YC5 Q70YC5 ZNF365 PTHR15739:SF2 ZINC FINGER PROTEIN PROTEIN ZNF365 HUMAN|HGNC=24700|UniProtKB=Q5QNW6 Q5QNW6 H2BC18 PTHR23428:SF160 HISTONE H2B HISTONE H2B TYPE 2-F nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=30129|UniProtKB=Q99575 Q99575 POP1 PTHR22731:SF3 RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1 RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1 catalytic activity, acting on RNA#GO:0140098;ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 small nucleolar ribonucleoprotein complex#GO:0005732;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;ribonuclease MRP complex#GO:0000172;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;ribonuclease P complex#GO:0030677;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=16617|UniProtKB=Q9C0J9 Q9C0J9 BHLHE41 PTHR10985:SF76 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 41 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;circadian regulation of gene expression#GO:0032922;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=845|UniProtKB=O75947 O75947 ATP5PD PTHR12700:SF17 ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide biosynthetic process#GO:0009152 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 HUMAN|HGNC=4222|UniProtKB=Q7Z4P5 Q7Z4P5 GDF7 PTHR11848:SF160 TGF-BETA FAMILY GROWTH/DIFFERENTIATION FACTOR 7 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=16036|UniProtKB=Q9P0S3 Q9P0S3 ORMDL1 PTHR12665:SF12 ORMDL PROTEINS ORM1-LIKE PROTEIN 1 negative regulation of cellular metabolic process#GO:0031324;lipid metabolic process#GO:0006629;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;biosynthetic process#GO:0009058;cellular homeostasis#GO:0019725;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of cellular component biogenesis#GO:0044087;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of lipid biosynthetic process#GO:0046890;negative regulation of cellular process#GO:0048523;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;chemical homeostasis#GO:0048878;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;cellular chemical homeostasis#GO:0055082;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;membrane lipid metabolic process#GO:0006643;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;ceramide biosynthetic process#GO:0046513;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;regulation of lipid metabolic process#GO:0019216;cellular lipid metabolic process#GO:0044255;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=13309|UniProtKB=Q9NQ84 Q9NQ84 GPRC5C PTHR14511:SF15 G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5 G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER C protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;protein kinase activity#GO:0004672;kinase activator activity#GO:0019209;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 receptor complex#GO:0043235;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=20876|UniProtKB=Q96S55 Q96S55 WRNIP1 PTHR13779:SF7 WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER ATPASE WRNIP1 pyrophosphatase activity#GO:0016462;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;biosynthetic process#GO:0009058;regulation of DNA repair#GO:0006282;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 DNA helicase#PC00011 HUMAN|HGNC=26387|UniProtKB=Q8ND83 Q8ND83 SLAIN1 PTHR22406:SF2 UNCHARACTERIZED SLAIN MOTIF-CONTAINING PROTEIN 1 HUMAN|HGNC=16926|UniProtKB=Q9BYQ4 Q9BYQ4 KRTAP9-2 PTHR23262:SF32 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-2-RELATED HUMAN|HGNC=26844|UniProtKB=Q8NEP4 Q8NEP4 C17orf47 PTHR37884:SF1 SEPTIN 4 SEPTIN 4 HUMAN|HGNC=20067|UniProtKB=Q8NB14 Q8NB14 USP38 PTHR24006:SF710 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 38 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=19372|UniProtKB=Q6EBC2 Q6EBC2 IL31 PTHR38652:SF1 INTERLEUKIN-31 INTERLEUKIN-31 binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;protein binding#GO:0005515;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interleukin superfamily#PC00128 HUMAN|HGNC=5987|UniProtKB=O95998 O95998 IL18BP PTHR14292:SF2 INTERLEUKIN-18-BINDING PROTEIN INTERLEUKIN-18-BINDING PROTEIN HUMAN|HGNC=25275|UniProtKB=Q68DN1 Q68DN1 C2orf16 PTHR33888:SF1 RIKEN CDNA 4932415D10 GENE RIKEN CDNA 4932415D10 GENE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=2432|UniProtKB=P09603 P09603 CSF1 PTHR10058:SF0 MACROPHAGE COLONY STIMULATING FACTOR MACROPHAGE COLONY-STIMULATING FACTOR 1 binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=10966|UniProtKB=O15244 O15244 SLC22A2 PTHR24064:SF432 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 2 ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;organic substance transport#GO:0071702;cation transport#GO:0006812;establishment of localization#GO:0051234;organic cation transport#GO:0015695;ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258 HUMAN|HGNC=25063|UniProtKB=Q6E0U4 Q6E0U4 DMKN PTHR36881:SF1 DERMOKINE DERMOKINE HUMAN|HGNC=11178|UniProtKB=O75908 O75908 SOAT2 PTHR10408:SF10 STEROL O-ACYLTRANSFERASE STEROL O-ACYLTRANSFERASE 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;sterol binding#GO:0032934;O-acyltransferase activity#GO:0008374;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;cholesterol binding#GO:0015485 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;organic hydroxy compound transport#GO:0015850;lipid metabolic process#GO:0006629;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;cholesterol metabolic process#GO:0008203;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;lipid modification#GO:0030258;cellular process#GO:0009987;lipid transport#GO:0006869;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;steroid metabolic process#GO:0008202;cholesterol transport#GO:0030301;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;lipid localization#GO:0010876;secondary alcohol metabolic process#GO:1902652;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 acyltransferase#PC00042 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 HUMAN|HGNC=6953|UniProtKB=P15529 P15529 CD46 PTHR19325:SF521 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING MEMBRANE COFACTOR PROTEIN HUMAN|HGNC=16525|UniProtKB=Q9H0N0 Q9H0N0 RAB6C PTHR24073:SF1089 DRAB5-RELATED RAS-RELATED PROTEIN RAB-6A-RELATED GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=30510|UniProtKB=Q76KD6 Q76KD6 SPATC1 PTHR22192:SF16 SPERIOLIN SPERIOLIN intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=28680|UniProtKB=Q9BUX1 Q9BUX1 CHAC1 PTHR12192:SF26 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1 lyase activity#GO:0016829;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=29073|UniProtKB=Q8IYA2 Q8IYA2 CCDC144CP PTHR22245:SF3 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 144A-RELATED HUMAN|HGNC=29436|UniProtKB=Q8WWB7 Q8WWB7 GLMP PTHR31981:SF1 GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7063|UniProtKB=Q99735 Q99735 MGST2 PTHR10250:SF13 MICROSOMAL GLUTATHIONE S-TRANSFERASE MICROSOMAL GLUTATHIONE S-TRANSFERASE 2 lyase activity#GO:0016829;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;icosanoid biosynthetic process#GO:0046456;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;fatty acid derivative metabolic process#GO:1901568;carboxylic acid biosynthetic process#GO:0046394;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=11598|UniProtKB=Q9UMR3 Q9UMR3 TBX20 PTHR11267:SF190 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX20 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 specification of symmetry#GO:0009799;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;heart looping#GO:0001947;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;heart development#GO:0007507;embryonic heart tube development#GO:0035050;determination of heart left/right asymmetry#GO:0061371;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;determination of bilateral symmetry#GO:0009855;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;determination of left/right symmetry#GO:0007368;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=24889|UniProtKB=Q6IPX1 Q6IPX1 TBC1D3C PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=28804|UniProtKB=Q8WTR4 Q8WTR4 GDPD5 PTHR23344:SF6 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN 5 phosphodiesterase#PC00185 HUMAN|HGNC=21686|UniProtKB=O00584 O00584 RNASET2 PTHR11240:SF22 RIBONUCLEASE T2 RIBONUCLEASE T2 HUMAN|HGNC=990|UniProtKB=P10415 P10415 BCL2 PTHR11256:SF11 BCL-2 RELATED APOPTOSIS REGULATOR BCL-2 identical protein binding#GO:0042802;protein binding#GO:0005515;protein homodimerization activity#GO:0042803;binding#GO:0005488 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;cell death#GO:0008219;intracellular signal transduction#GO:0035556;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;negative regulation of signaling#GO:0023057;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of response to stimulus#GO:0048583;negative regulation of cell death#GO:0060548;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of intrinsic apoptotic signaling pathway#GO:2001242;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Oxidative stress response#P00046>Bcl-2#P01123;CCKR signaling map#P06959>BCL2#P07059;Apoptosis signaling pathway#P00006>Bcl-2#P00270 HUMAN|HGNC=28713|UniProtKB=Q5T6C5 Q5T6C5 ATXN7L2 PTHR15117:SF5 ATAXIN 7 RELATED ATAXIN-7-LIKE PROTEIN 2 HUMAN|HGNC=7837|UniProtKB=Q9H2Z4 Q9H2Z4 NKX2-4 PTHR24340:SF40 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|Ensembl=ENSG00000284690|UniProtKB=A0A0K2S4Q6 A0A0K2S4Q6 CD300H PTHR11860:SF87 POLYMERIC-IMMUNOGLOBULIN RECEPTOR PROTEIN CD300H immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=16736|UniProtKB=Q86Y25 Q86Y25 ZNF354C PTHR24377:SF937 IP01015P-RELATED ZINC FINGER PROTEIN 354C cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4612|UniProtKB=P56915 P56915 GSC PTHR46643:SF2 HOMEOBOX PROTEIN GOOSECOID-RELATED HOMEOBOX PROTEIN GOOSECOID cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=11072|UniProtKB=Q9UBY0 Q9UBY0 SLC9A2 PTHR10110:SF89 SODIUM/HYDROGEN EXCHANGER SODIUM/HYDROGEN EXCHANGER 2 secondary carrier transporter#PC00258 HUMAN|HGNC=7698|UniProtKB=O43676 O43676 NDUFB3 PTHR15082:SF2 NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=25147|UniProtKB=Q8NCI6 Q8NCI6 GLB1L3 PTHR23421:SF59 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE-1-LIKE PROTEIN 3 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 galactosidase#PC00104 HUMAN|HGNC=17822|UniProtKB=Q9H7Z7 Q9H7Z7 PTGES2 PTHR12782:SF5 MICROSOMAL PROSTAGLANDIN E SYNTHASE-2 PROSTAGLANDIN E SYNTHASE 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 reductase#PC00198 HUMAN|HGNC=6088|UniProtKB=Q9Y5Q6 Q9Y5Q6 INSL5 PTHR20968:SF2 ILGF DOMAIN-CONTAINING PROTEIN INSULIN-LIKE PEPTIDE INSL5 HUMAN|HGNC=10257|UniProtKB=Q01974 Q01974 ROR2 PTHR24416:SF132 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=8804|UniProtKB=P09619 P09619 PDGFRB PTHR24416:SF53 TYROSINE-PROTEIN KINASE RECEPTOR PLATELET-DERIVED GROWTH FACTOR RECEPTOR BETA signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of localization#GO:0032879;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of cellular component movement#GO:0051272;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;regulation of cell migration#GO:0030334;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;positive regulation of cell motility#GO:2000147;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;regulation of cellular component movement#GO:0051270;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of locomotion#GO:0040017;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;cell migration#GO:0016477;regulation of transferase activity#GO:0051338;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 PDGF signaling pathway#P00047>PDGF receptor B#P01156;Angiogenesis#P00005>PDGFR#P00230 HUMAN|HGNC=3806|UniProtKB=O00358 O00358 FOXE1 PTHR11829:SF368 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN E1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=14986|UniProtKB=O60641 O60641 SNAP91 PTHR22951:SF4 CLATHRIN ASSEMBLY PROTEIN CLATHRIN COAT ASSEMBLY PROTEIN AP180 phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;vesicle localization#GO:0051648;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;establishment of organelle localization#GO:0051656;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;presynaptic membrane#GO:0042734;vesicle#GO:0031982;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=9540|UniProtKB=P49720 P49720 PSMB3 PTHR11599:SF185 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-3 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=9902|UniProtKB=P52756 P52756 RBM5 PTHR13948:SF21 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28915|UniProtKB=Q9NR55 Q9NR55 BATF3 PTHR23351:SF13 FOS TRANSCRIPTION FACTOR-RELATED BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=94|UniProtKB=Q9BWD1 Q9BWD1 ACAT2 PTHR18919:SF81 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=17353|UniProtKB=Q9NRW3 Q9NRW3 APOBEC3C PTHR13857:SF41 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3C RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363 response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;RNA phosphodiester bond hydrolysis#GO:0090501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;defense response to virus#GO:0051607;demethylation#GO:0070988;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;transposition#GO:0032196;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;RNA-dependent DNA biosynthetic process#GO:0006278;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;nucleic acid phosphodiester bond hydrolysis#GO:0090305;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147 HUMAN|HGNC=15948|UniProtKB=Q8N5A5 Q8N5A5 ZGPAT PTHR46297:SF1 ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=16516|UniProtKB=P57682 P57682 KLF3 PTHR23235:SF48 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1771|UniProtKB=P24941 P24941 CDK2 PTHR24056:SF521 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 2 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;protein modification process#GO:0036211;cell population proliferation#GO:0008283;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of cell population proliferation#GO:0042127;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;G2/M transition of mitotic cell cycle#GO:0000086;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>Cdc2#P04634;p53 pathway feedback loops 2#P04398>cdk2#P04653;p53 pathway#P00059>Cdk2#P04625 HUMAN|HGNC=2719|UniProtKB=P20711 P20711 DDC PTHR11999:SF70 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE AROMATIC-L-AMINO-ACID DECARBOXYLASE decarboxylase#PC00089 Nicotine pharmacodynamics pathway#P06587>DDC#P06608;5-Hydroxytryptamine biosynthesis#P04371>Aromatic L-amino acid decarboxylase#P04400;Dopamine receptor mediated signaling pathway#P05912>DOPA decarb.#P05961;Adrenaline and noradrenaline biosynthesis#P00001>DOPA decarb.#P00066 HUMAN|HGNC=17590|UniProtKB=Q9HB07 Q9HB07 MYG1 PTHR11215:SF1 METAL DEPENDENT HYDROLASE - RELATED MYG1 EXONUCLEASE hydrolase#PC00121 HUMAN|HGNC=8584|UniProtKB=P05120 P05120 SERPINB2 PTHR11461:SF61 SERINE PROTEASE INHIBITOR, SERPIN PLASMINOGEN ACTIVATOR INHIBITOR 2 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 CCKR signaling map#P06959>PAI2#G06977;Plasminogen activating cascade#P00050>PAI-2#P01244;Blood coagulation#P00011>PAI-2#P00409;CCKR signaling map#P06959>PAI2#G07270 HUMAN|HGNC=26956|UniProtKB=Q9ULG1 Q9ULG1 INO80 PTHR45685:SF2 HELICASE SRCAP-RELATED CHROMATIN-REMODELING ATPASE INO80 pyrophosphatase activity#GO:0016462;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;histone binding#GO:0042393;ATPase activity#GO:0016887 DNA repair#GO:0006281;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;regulation of transcription from RNA polymerase II promoter in response to stress#GO:0043618;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;nucleosome organization#GO:0034728;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;Ino80 complex#GO:0031011;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=23239|UniProtKB=Q8WTR7 Q8WTR7 ZNF473 PTHR24376:SF93 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 473 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=8891|UniProtKB=P52209 P52209 PGD PTHR11811:SF50 6-PHOSPHOGLUCONATE DEHYDROGENASE 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;NADP binding#GO:0050661;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glucose 6-phosphate metabolic process#GO:0051156;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;carbohydrate metabolic process#GO:0005975;NADP metabolic process#GO:0006739;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 Pentose phosphate pathway#P02762>Gluconate Dehydrogenase#P03070 HUMAN|HGNC=13370|UniProtKB=Q9NXJ0 Q9NXJ0 MS4A12 PTHR23320:SF72 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 12 transporter#PC00227 HUMAN|HGNC=1711|UniProtKB=P48960 P48960 ADGRE5 PTHR12011:SF348 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=2514|UniProtKB=P35222 P35222 CTNNB1 PTHR45976:SF4 ARMADILLO SEGMENT POLARITY PROTEIN CATENIN BETA-1 phosphatase binding#GO:0019902;binding#GO:0005488;transcription coactivator activity#GO:0003713;cadherin binding#GO:0045296;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;signaling receptor binding#GO:0005102;DNA-binding transcription factor binding#GO:0140297;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;hormone receptor binding#GO:0051427 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 Cadherin signaling pathway#P00012>betacatenin#P00463;p53 pathway feedback loops 2#P04398>beta-catenin#P04670;Wnt signaling pathway#P00057>Beta-Catenin#P01432;Angiogenesis#P00005>beta catenin#P00187;Alzheimer disease-presenilin pathway#P00004>beta-catenin#P00156;CCKR signaling map#P06959>beta-catenin#P07150;Gonadotropin-releasing hormone receptor pathway#P06664>CTNNB1#P06838 HUMAN|HGNC=30577|UniProtKB=Q96AX9 Q96AX9 MIB2 PTHR24202:SF4 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB2 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=25152|UniProtKB=Q9BSF4 Q9BSF4 TIMM29 PTHR21435:SF1 UNCHARACTERIZED MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 cellular localization#GO:0051641;protein insertion into mitochondrial inner membrane#GO:0045039;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=20917|UniProtKB=Q96QP1 Q96QP1 ALPK1 PTHR46747:SF1 ALPHA-PROTEIN KINASE 1 ALPHA-PROTEIN KINASE 1 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=5439|UniProtKB=P15260 P15260 IFNGR1 PTHR20859:SF5 INTERFERON/INTERLEUKIN RECEPTOR INTERFERON GAMMA RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cytokine receptor#P00866;Interferon-gamma signaling pathway#P00035>IFNGR1#P00959 HUMAN|HGNC=13593|UniProtKB=Q8NEZ5 Q8NEZ5 FBXO22 PTHR14939:SF5 F-BOX ONLY PROTEIN 22 F-BOX ONLY PROTEIN 22 HUMAN|HGNC=25857|UniProtKB=Q8NE18 Q8NE18 NSUN7 PTHR14663:SF2 UNCHARACTERIZED METHYLTRANSFERASE NSUN7-RELATED HUMAN|HGNC=3538|UniProtKB=P55085 P55085 F2RL1 PTHR24232:SF21 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=14867|UniProtKB=Q9BPW4 Q9BPW4 APOL4 PTHR14096:SF39 APOLIPOPROTEIN L APOLIPOPROTEIN L4 lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052 HUMAN|HGNC=30163|UniProtKB=O60678 O60678 PRMT3 PTHR11006:SF114 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 3 protein modifying enzyme#PC00260 HUMAN|HGNC=5733|UniProtKB=P01599 P01599 IGKV1-17 PTHR23267:SF384 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-16-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=25839|UniProtKB=Q8TE85 Q8TE85 GRHL3 PTHR11037:SF6 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 3 HOMOLOG DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=24634|UniProtKB=Q9UBC2 Q9UBC2 EPS15L1 PTHR11216:SF69 EH DOMAIN EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15-LIKE 1 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane coat#GO:0030117;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=8736|UniProtKB=A6NKB5 A6NKB5 PCNX2 PTHR12372:SF5 PECANEX PECANEX-LIKE PROTEIN 2 HUMAN|HGNC=30220|UniProtKB=Q96AA3 Q96AA3 RFT1 PTHR13117:SF5 ENDOPLASMIC RETICULUM MULTISPAN TRANSMEMBRANE PROTEIN-RELATED PROTEIN RFT1 HOMOLOG macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;organic substance transport#GO:0071702;cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;lipid translocation#GO:0034204;biological regulation#GO:0065007;lipid localization#GO:0010876;carbohydrate derivative transport#GO:1901264 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=27997|UniProtKB=O60809 O60809 PRAMEF10 PTHR14224:SF28 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 10-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=15961|UniProtKB=Q9ULV8 Q9ULV8 CBLC PTHR23007:SF12 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL-C transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;regulation of signaling receptor activity#GO:0010469;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857;membrane region#GO:0098589;plasma membrane#GO:0005886;whole membrane#GO:0098805 ligase#PC00142 EGF receptor signaling pathway#P00018>c-Cbl#P00544 HUMAN|HGNC=37266|UniProtKB=P0CJ90 P0CJ90 DUX4L7 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=15741|UniProtKB=Q9NZH8 Q9NZH8 IL36G PTHR10078:SF27 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-36 GAMMA receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to lipopolysaccharide#GO:0071222;gene expression#GO:0010467;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of metabolic process#GO:0009893;response to biotic stimulus#GO:0009607;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 interleukin superfamily#PC00128 HUMAN|HGNC=12774|UniProtKB=P04628 P04628 WNT1 PTHR12027:SF91 WNT RELATED PROTO-ONCOGENE WNT-1 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=33711|UniProtKB=Q68D91 Q68D91 MBLAC2 PTHR42951:SF4 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 2 hydrolase#PC00121 HUMAN|HGNC=20116|UniProtKB=Q8N8R3 Q8N8R3 SLC25A29 PTHR45624:SF10 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER localization#GO:0051179;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;anion transport#GO:0006820;organic cation transport#GO:0015695;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812 transporter#PC00227 HUMAN|HGNC=13093|UniProtKB=P17040 P17040 ZSCAN20 PTHR23226:SF220 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 20 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=5991|UniProtKB=P01583 P01583 IL1A PTHR10078:SF33 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 ALPHA positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;response to cytokine#GO:0034097;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;regulation of molecular function#GO:0065009;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;oxidation-reduction process#GO:0055114;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;cell adhesion#GO:0007155;positive regulation of T cell differentiation#GO:0045582;positive regulation of macromolecule metabolic process#GO:0010604;response to lipopolysaccharide#GO:0032496;T cell differentiation#GO:0030217;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to stress#GO:0006950;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;cellular response to lipopolysaccharide#GO:0071222;animal organ development#GO:0048513;biological adhesion#GO:0022610;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;cellular response to lipid#GO:0071396;inflammatory response#GO:0006954;leukocyte cell-cell adhesion#GO:0007159;system development#GO:0048731;cell differentiation#GO:0030154;T cell proliferation#GO:0042098;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;regulation of hemopoiesis#GO:1903706;positive regulation of metabolic process#GO:0009893;positive regulation of leukocyte cell-cell adhesion#GO:1903039;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;positive regulation of cell differentiation#GO:0045597;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;multicellular organism development#GO:0007275;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of T cell proliferation#GO:0042129;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;lymphocyte differentiation#GO:0030098;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;positive regulation of cell adhesion#GO:0045785;regulation of leukocyte proliferation#GO:0070663;positive regulation of cell-cell adhesion#GO:0022409 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Interleukin#P00970;Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=19069|UniProtKB=Q9H227 Q9H227 GBA3 PTHR10353:SF291 GLYCOSYL HYDROLASE CYTOSOLIC BETA-GLUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110 HUMAN|HGNC=28396|UniProtKB=Q5HYA8 Q5HYA8 TMEM67 PTHR21274:SF0 UNCHARACTERIZED MECKELIN HUMAN|HGNC=25976|UniProtKB=Q0PNE2 Q0PNE2 ELP6 PTHR16184:SF6 ELONGATOR COMPLEX PROTEIN 6 ELONGATOR COMPLEX PROTEIN 6 protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=33785|UniProtKB=Q69YZ2 Q69YZ2 TMEM200B PTHR31815:SF3 AGAP005329-PA TRANSMEMBRANE PROTEIN 200B HUMAN|HGNC=3014|UniProtKB=Q16555 Q16555 DPYSL2 PTHR11647:SF56 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE-RELATED PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824;dihydropyrimidinase activity#GO:0004157 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;pyrimidine nucleobase metabolic process#GO:0006206;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;pyrimidine nucleobase catabolic process#GO:0006208;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125;Axon guidance mediated by semaphorins#P00007>CRMP#P00339 HUMAN|HGNC=14823|UniProtKB=Q8NGX8 Q8NGX8 OR6Y1 PTHR26453:SF109 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6Y1 transmembrane signal receptor#PC00197 HUMAN|HGNC=30616|UniProtKB=P60008 P60008 H1-9P PTHR11467:SF28 HISTONE H1 SPERMATID-SPECIFIC LINKER HISTONE H1-LIKE PROTEIN-RELATED nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of chromatin silencing#GO:0031935;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of chromatin silencing#GO:0031936;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of chromatin organization#GO:1902275;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;chromosome condensation#GO:0030261;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of DNA recombination#GO:0000018;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone#PC00118 HUMAN|Gene=SEP15|UniProtKB=O60613 O60613 SELENOF PTHR13077:SF6 SELENOPROTEIN F SELENOPROTEIN F catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=15898|UniProtKB=Q9H501 Q9H501 ESF1 PTHR12202:SF0 UNCHARACTERIZED ESF1 HOMOLOG nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=8032|UniProtKB=Q16620 Q16620 NTRK2 PTHR24416:SF136 TYROSINE-PROTEIN KINASE RECEPTOR BDNF/NT-3 GROWTH FACTORS RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 positive regulation of cellular metabolic process#GO:0031325;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;trans-synaptic signaling#GO:0099537;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;anatomical structure development#GO:0048856;protein kinase B signaling#GO:0043491;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to growth factor#GO:0070848;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;response to endogenous stimulus#GO:0009719;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;signaling#GO:0023052;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;regulation of protein kinase B signaling#GO:0051896;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=16315|UniProtKB=Q96L94 Q96L94 SNX22 PTHR15813:SF8 SORTING NEXIN-22 AND 24 SORTING NEXIN-22 scaffold/adaptor protein#PC00226 HUMAN|HGNC=14654|UniProtKB=Q9HBI0 Q9HBI0 PARVG PTHR12114:SF1 PARVIN GAMMA-PARVIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;actin cytoskeleton reorganization#GO:0031532;cell morphogenesis involved in differentiation#GO:0000904;developmental process#GO:0032502;biological adhesion#GO:0022610;substrate adhesion-dependent cell spreading#GO:0034446;cell morphogenesis#GO:0000902;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;intracellular#GO:0005622;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 HUMAN|HGNC=7955|UniProtKB=P01303 P01303 NPY PTHR10533:SF5 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PRO-NEUROPEPTIDE Y neuropeptide hormone activity#GO:0005184;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;behavior#GO:0007610;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intercellular signal molecule#PC00207 HUMAN|HGNC=2205|UniProtKB=Q9Y5P4 Q9Y5P4 CERT1 PTHR10219:SF71 GLYCOLIPID TRANSFER PROTEIN-RELATED CERAMIDE TRANSFER PROTEIN binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;lipid transporter activity#GO:0005319;transporter activity#GO:0005215 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;lipid transport#GO:0006869;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;lipid localization#GO:0010876 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 HUMAN|HGNC=13843|UniProtKB=A6NFI3 A6NFI3 ZNF316 PTHR24408:SF54 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 316-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26038|UniProtKB=O75204 O75204 TMEM127 PTHR28358:SF1 TRANSMEMBRANE PROTEIN 127 TRANSMEMBRANE PROTEIN 127 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052;TOR signaling#GO:0031929 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=14769|UniProtKB=Q8NGJ4 Q8NGJ4 OR52E2 PTHR26450:SF392 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E2 transmembrane signal receptor#PC00197 HUMAN|HGNC=21198|UniProtKB=Q9NWW0 Q9NWW0 HCFC1R1 PTHR16246:SF2 HOST CELL FACTOR C1 REGULATOR 1 HOST CELL FACTOR C1 REGULATOR 1 HUMAN|HGNC=16528|UniProtKB=Q9UK85 Q9UK85 DKKL1 PTHR12113:SF7 DICKKOPF3-LIKE 3 DICKKOPF-LIKE PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=15436|UniProtKB=Q9NZP2 Q9NZP2 OR6C2 PTHR26454:SF8 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=14875|UniProtKB=Q96LA5 Q96LA5 FCRL2 PTHR11481:SF101 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=10261|UniProtKB=P08922 P08922 ROS1 PTHR24416:SF527 TYROSINE-PROTEIN KINASE RECEPTOR PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=3166|UniProtKB=Q92633 Q92633 LPAR1 PTHR22750:SF22 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 1 carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;binding#GO:0005488;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;phospholipid binding#GO:0005543;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;divalent inorganic cation homeostasis#GO:0072507;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of cAMP-mediated signaling#GO:0043949;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of phospholipase C activity#GO:0010863;cellular developmental process#GO:0048869;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of response to stimulus#GO:0048583;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;neurogenesis#GO:0022008;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;cell differentiation#GO:0030154;system development#GO:0048731;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;signaling#GO:0023052;metabolic process#GO:0008152;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=30482|UniProtKB=Q5VZ03 Q5VZ03 NXNL2 PTHR46762:SF1 NUCLEOREDOXIN-LIKE PROTEIN 2 NUCLEOREDOXIN-LIKE PROTEIN 2 oxidoreductase#PC00176 HUMAN|HGNC=19894|UniProtKB=Q9Y5R8 Q9Y5R8 TRAPPC1 PTHR23249:SF16 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 1 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008 membrane traffic protein#PC00150 HUMAN|HGNC=22564|UniProtKB=A4D263 A4D263 SPATA48 PTHR34759:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 48 SPERMATOGENESIS-ASSOCIATED PROTEIN 48 HUMAN|HGNC=15566|UniProtKB=Q9H0C8 Q9H0C8 ILKAP PTHR13832:SF803 PROTEIN PHOSPHATASE 2C INTEGRIN-LINKED KINASE-ASSOCIATED SERINE/THREONINE PHOSPHATASE 2C hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=13534|UniProtKB=P98198 P98198 ATP8B2 PTHR24092:SF46 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE ID pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=32681|UniProtKB=Q5MJ68 Q5MJ68 SPDYC PTHR31545:SF2 SEEDY PROTEIN A/C FAMILY MEMBER SPEEDY PROTEIN C HUMAN|HGNC=3257|UniProtKB=Q14232 Q14232 EIF2B1 PTHR45860:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA translation initiation factor#PC00224 HUMAN|HGNC=12520|UniProtKB=Q92890 Q92890 UFD1 PTHR12555:SF20 UBIQUITIN FUSION DEGRADATON PROTEIN 1 UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 cellular response to misfolded protein#GO:0071218;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;response to topologically incorrect protein#GO:0035966;ubiquitin-dependent ERAD pathway#GO:0030433;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=12179|UniProtKB=A0A0K0K1G6 A0A0K0K1G6 TRBV10-3 PTHR23268:SF42 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 10-3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=33891|UniProtKB=A6NNM3 A6NNM3 RIMBP3B PTHR14234:SF21 RIM BINDING PROTEIN-RELATED RIMS-BINDING PROTEIN 3A-RELATED germ cell development#GO:0007281;male gamete generation#GO:0048232;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;developmental process#GO:0032502;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;spermatid differentiation#GO:0048515;cellular process#GO:0009987;multi-organism process#GO:0051704;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;spermatid development#GO:0007286;reproduction#GO:0000003;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;synaptic signaling#GO:0099536;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;neuromuscular synaptic transmission#GO:0007274;multi-organism reproductive process#GO:0044703;cell-cell signaling#GO:0007267;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7437|UniProtKB=P49914 P49914 MTHFS PTHR23407:SF1 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;pteridine-containing compound metabolic process#GO:0042558;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;heterocycle biosynthetic process#GO:0018130;amide biosynthetic process#GO:0043604;folic acid-containing compound biosynthetic process#GO:0009396;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 ligase#PC00142 HUMAN|HGNC=28392|UniProtKB=Q6UWM5 Q6UWM5 GLIPR1L1 PTHR10334:SF220 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIPR1-LIKE PROTEIN 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=1131|UniProtKB=P78543 P78543 BTG2 PTHR22978:SF29 B-CELL TRANSLOCATION GENE PROTEIN BTG2 negative regulation of biological process#GO:0048519;regulation of cell population proliferation#GO:0042127;negative regulation of cell cycle#GO:0045786;nuclear division#GO:0000280;cell cycle process#GO:0022402;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular process#GO:0009987;cell population proliferation#GO:0008283;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;negative regulation of cell population proliferation#GO:0008285;regulation of mitotic cell cycle#GO:0007346;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16872|UniProtKB=Q8TB61 Q8TB61 SLC35B2 PTHR10778:SF13 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;organophosphate ester transmembrane transporter activity#GO:0015605;ion transmembrane transporter activity#GO:0015075;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide transmembrane transporter activity#GO:0015215;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 secondary carrier transporter#PC00258 HUMAN|HGNC=21356|UniProtKB=Q6QEF8 Q6QEF8 CORO6 PTHR10856:SF23 CORONIN CORONIN-6 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 non-motor actin binding protein#PC00165 HUMAN|HGNC=8803|UniProtKB=P16234 P16234 PDGFRA PTHR24416:SF52 TYROSINE-PROTEIN KINASE RECEPTOR PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 embryonic organ morphogenesis#GO:0048562;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;animal organ development#GO:0048513;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;skeletal system development#GO:0001501;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;chordate embryonic development#GO:0043009;response to stimulus#GO:0050896;embryonic organ development#GO:0048568;embryo development#GO:0009790;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;embryo development ending in birth or egg hatching#GO:0009792;animal organ morphogenesis#GO:0009887;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;embryonic morphogenesis#GO:0048598;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 PDGF signaling pathway#P00047>PDGF receptor A#P01158;Angiogenesis#P00005>PDGFR#P00230 HUMAN|HGNC=1632|UniProtKB=Q04900 Q04900 CD164 PTHR11337:SF12 MUCIN/PORIMIN SIALOMUCIN CORE PROTEIN 24 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=6555|UniProtKB=O95214 O95214 LEPROTL1 PTHR12050:SF4 LEPTIN RECEPTOR-RELATED LEPTIN RECEPTOR OVERLAPPING TRANSCRIPT-LIKE 1 endosomal transport#GO:0016197;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;cellular protein localization#GO:0034613;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;late endosome to vacuole transport#GO:0045324;protein localization to cell surface#GO:0034394;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;regulation of cellular localization#GO:0060341;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;endosome transport via multivesicular body sorting pathway#GO:0032509;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;regulation of protein localization#GO:0032880 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=1386|UniProtKB=P57796 P57796 CABP4 PTHR45917:SF4 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 4 HUMAN|HGNC=26755|UniProtKB=Q8N1Q8 Q8N1Q8 THEM5 PTHR47362:SF1 ACYL-COENZYME A THIOESTERASE THEM5 ACYL-COENZYME A THIOESTERASE THEM5 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;phospholipid metabolic process#GO:0006644;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;glycerolipid metabolic process#GO:0046486;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;fatty acid derivative metabolic process#GO:1901568;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;phosphatidylglycerol metabolic process#GO:0046471;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 esterase#PC00097 HUMAN|HGNC=7745|UniProtKB=P51955 P51955 NEK2 PTHR43671:SF13 SERINE/THREONINE-PROTEIN KINASE NEK SERINE/THREONINE-PROTEIN KINASE NEK10-RELATED non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=19575|UniProtKB=A6ND48 A6ND48 OR14I1 PTHR26452:SF832 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14I1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=2187|UniProtKB=P13942 P13942 COL11A2 PTHR24023:SF509 COLLAGEN ALPHA COLLAGEN ALPHA-2(XI) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 sensory perception of sound#GO:0007605;animal organ development#GO:0048513;collagen fibril organization#GO:0030199;multicellular organism development#GO:0007275;system process#GO:0003008;developmental process#GO:0032502;connective tissue development#GO:0061448;nervous system process#GO:0050877;cellular component organization#GO:0016043;skeletal system development#GO:0001501;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;tissue development#GO:0009888;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;extracellular structure organization#GO:0043062;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;cartilage development#GO:0051216 extracellular matrix#GO:0031012;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=15534|UniProtKB=Q969V4 Q969V4 TEKT1 PTHR19960:SF25 TEKTIN TEKTIN-1 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cilium movement involved in cell motility#GO:0060294;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=567|UniProtKB=Q13367 Q13367 AP3B2 PTHR11134:SF11 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA-2 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;microtubule-based movement#GO:0007018;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;transport along microtubule#GO:0010970;localization#GO:0051179;axo-dendritic transport#GO:0008088;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;establishment of organelle localization#GO:0051656;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 membrane traffic protein#PC00150 HUMAN|HGNC=93|UniProtKB=P24752 P24752 ACAT1 PTHR18919:SF156 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 CCKR signaling map#P06959>ACAT1#G07285;CCKR signaling map#P06959>ACAT1#G06992 HUMAN|HGNC=2082|UniProtKB=O15516 O15516 CLOCK PTHR46055:SF2 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;multicellular organismal process#GO:0032501;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Circadian clock system#P00015>Clock#P00501 HUMAN|HGNC=17801|UniProtKB=Q8NHY6 Q8NHY6 ZFP28 PTHR24377:SF212 IP01015P-RELATED ZINC FINGER PROTEIN 28 HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=6229|UniProtKB=Q13303 Q13303 KCNAB2 PTHR43150:SF1 HYPERKINETIC, ISOFORM M VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;protein binding#GO:0005515;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;action potential#GO:0001508;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;oxidation-reduction process#GO:0055114;metabolic process#GO:0008152;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;monovalent inorganic cation transport#GO:0015672;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;regulation of ion transport#GO:0043269 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;side of membrane#GO:0098552;cation channel complex#GO:0034703;axon#GO:0030424;extrinsic component of membrane#GO:0019898;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 HUMAN|HGNC=19205|UniProtKB=Q9P246 Q9P246 STIM2 PTHR15136:SF2 STROMAL INTERACTION MOLECULE HOMOLOG STROMAL INTERACTION MOLECULE 2 cation binding#GO:0043169;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;molecular function regulator#GO:0098772;ion binding#GO:0043167;channel regulator activity#GO:0016247;transporter activity#GO:0005215;channel activity#GO:0015267 positive regulation of ion transport#GO:0043270;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of molecular function#GO:0044093;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;regulation of molecular function#GO:0065009;positive regulation of transmembrane transport#GO:0034764;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;cellular cation homeostasis#GO:0030003;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;regulation of calcium ion transport#GO:0051924;homeostatic process#GO:0042592;positive regulation of ion transmembrane transporter activity#GO:0032414;positive regulation of transport#GO:0051050;cation homeostasis#GO:0055080;positive regulation of calcium ion transport#GO:0051928;chemical homeostasis#GO:0048878;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of ion transmembrane transport#GO:0034765;positive regulation of transporter activity#GO:0032411;regulation of cellular process#GO:0050794;positive regulation of ion transmembrane transport#GO:0034767;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=21082|UniProtKB=Q9UGP8 Q9UGP8 SEC63 PTHR24075:SF0 SEC63 DOMAIN-CONTAINING TRANSLOCATION PROTEIN SEC63 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;transmembrane transporter activity#GO:0022857;binding#GO:0005488;organic cyclic compound binding#GO:0097159;amide transmembrane transporter activity#GO:0042887;protein transmembrane transporter activity#GO:0008320;heterocyclic compound binding#GO:1901363;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;translation#GO:0006412;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;posttranslational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein localization to organelle#GO:0033365;cellular protein metabolic process#GO:0044267;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;protein localization to endoplasmic reticulum#GO:0070972;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;amide biosynthetic process#GO:0043604;protein targeting to membrane#GO:0006612;peptide biosynthetic process#GO:0043043;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=8543|UniProtKB=Q15077 Q15077 P2RY6 PTHR24231:SF16 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 6 G-protein coupled receptor#PC00021 HUMAN|HGNC=8775|UniProtKB=Q01064 Q01064 PDE1B PTHR11347:SF194 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CALCIUM/CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1B hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 HUMAN|HGNC=16388|UniProtKB=Q9BZF3 Q9BZF3 OSBPL6 PTHR10972:SF76 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 6 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;cholesterol binding#GO:0015485 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=5323|UniProtKB=Q2M3T9 Q2M3T9 HYAL4 PTHR11769:SF7 HYALURONIDASE HYALURONIDASE-4 glycosidase#PC00110 HUMAN|HGNC=9642|UniProtKB=P18031 P18031 PTPN1 PTHR46047:SF2 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 protein phosphatase#PC00195 Cadherin signaling pathway#P00012>Tyrosine phosphatases#P00472 HUMAN|HGNC=19655|UniProtKB=Q7RTT3 Q7RTT3 SSX9P PTHR14112:SF24 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX7-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=18936|UniProtKB=Q8IUB9 Q8IUB9 KRTAP19-1 PTHR38140:SF6 KERATIN-ASSOCIATED PROTEIN 19-3-RELATED KERATIN-ASSOCIATED PROTEIN 19-1 HUMAN|HGNC=12232|UniProtKB=A0A0A0MS04 A0A0A0MS04 TRBV6-7 PTHR23268:SF86 T-CELL RECEPTOR BETA CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=26133|UniProtKB=Q9H720 Q9H720 CWH43 PTHR14859:SF1 CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR PGAP2-INTERACTING PROTEIN lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein lipidation#GO:0006497;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=6646|UniProtKB=Q8WWI1 Q8WWI1 LMO7 PTHR46767:SF1 LIM DOMAIN ONLY PROTEIN 7 LIM DOMAIN ONLY PROTEIN 7 HUMAN|HGNC=13945|UniProtKB=Q9Y4H4 Q9Y4H4 GPSM3 PTHR47617:SF1 G-PROTEIN SIGNALING MODULATOR 3 G-PROTEIN-SIGNALING MODULATOR 3 HUMAN|HGNC=14209|UniProtKB=Q86UD4 Q86UD4 ZNF329 PTHR24381:SF118 ZINC FINGER PROTEIN ZINC FINGER IMPRINTED 2-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=37331|UniProtKB=Q8TDU5 Q8TDU5 VN1R17P PTHR24062:SF174 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 5-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=978|UniProtKB=Q9P287 Q9P287 BCCIP PTHR13261:SF0 BRCA2 AND CDKN1A INTERACTING PROTEIN BRCA2 AND CDKN1A-INTERACTING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=33435|UniProtKB=Q5U4N7 Q5U4N7 GDF5-AS1 PTHR42152:SF1 PROTEIN GDF5OS, MITOCHONDRIAL PROTEIN GDF5-AS1, MITOCHONDRIAL HUMAN|HGNC=13481|UniProtKB=Q9H1C4 Q9H1C4 UNC93B1 PTHR46744:SF1 PROTEIN UNC-93 HOMOLOG B1 PROTEIN UNC-93 HOMOLOG B1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;pattern recognition receptor signaling pathway#GO:0002221;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;signaling#GO:0023052 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=28246|UniProtKB=Q96ID5 Q96ID5 IGSF21 PTHR23277:SF108 NECTIN-RELATED IMMUNOGLOBULIN SUPERFAMILY MEMBER 21 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;biological adhesion#GO:0022610 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 HUMAN|HGNC=24709|UniProtKB=Q5GFL6 Q5GFL6 VWA2 PTHR24020:SF37 COLLAGEN ALPHA VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 2 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;biological adhesion#GO:0022610 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=19422|UniProtKB=O75528 O75528 TADA3 PTHR13556:SF2 TRANSCRIPTIONAL ADAPTER 3-RELATED TRANSCRIPTIONAL ADAPTER 3 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;N-acyltransferase activity#GO:0016410 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone H4 acetylation#GO:0043967;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;histone H3 acetylation#GO:0043966;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;histone acetylation#GO:0016573;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=21969|UniProtKB=P0C7M8 P0C7M8 CLEC2L PTHR47498:SF1 C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER L C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER L HUMAN|HGNC=20272|UniProtKB=Q8ND23 Q8ND23 CARMIL3 PTHR24112:SF43 LEUCINE-RICH REPEAT, ISOFORM F-RELATED CAPPING PROTEIN, ARP2/3 AND MYOSIN-I LINKER PROTEIN 3 HUMAN|HGNC=6369|UniProtKB=O60259 O60259 KLK8 PTHR24271:SF62 KALLIKREIN-RELATED KALLIKREIN-8 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=12801|UniProtKB=P17861 P17861 XBP1 PTHR46542:SF3 X-BOX BINDING PROTEIN 1 X-BOX-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;response to endoplasmic reticulum stress#GO:0034976;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;response to unfolded protein#GO:0006986;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26467|UniProtKB=Q8N4Q1 Q8N4Q1 CHCHD4 PTHR21622:SF6 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 MITOCHONDRIAL INTERMEMBRANE SPACE IMPORT AND ASSEMBLY PROTEIN 40 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein metabolic process#GO:0019538;mitochondrial transmembrane transport#GO:1990542;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;transmembrane transport#GO:0055085;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;peptide transport#GO:0015833;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein folding#GO:0006457;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 membrane-enclosed lumen#GO:0031974;envelope#GO:0031975;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 HUMAN|HGNC=3796|UniProtKB=P01100 P01100 FOS PTHR23351:SF4 FOS TRANSCRIPTION FACTOR-RELATED PROTO-ONCOGENE C-FOS cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 Interleukin signaling pathway#P00036>c-fos#P00967;CCKR signaling map#P06959>FOS#P07035;PDGF signaling pathway#P00047>c-fos#P01145;Gonadotropin-releasing hormone receptor pathway#P06664>c-fos#G06680;Gonadotropin-releasing hormone receptor pathway#P06664>c-fos#G06894;Gonadotropin-releasing hormone receptor pathway#P06664>FOS#P06709;Angiogenesis#P00005>c-Fos#P00235;Apoptosis signaling pathway#P00006>Fos#P00317;CCKR signaling map#P06959>FOS#G06973;CCKR signaling map#P06959>FOS#G07266;Huntington disease#P00029>Fos protein#P00801;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>c-fos#P00884;B cell activation#P00010>fos#P00380;T cell activation#P00053>fos#P01309 HUMAN|HGNC=11388|UniProtKB=O94804 O94804 STK10 PTHR48012:SF2 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE/THREONINE-PROTEIN KINASE 10 HUMAN|HGNC=20442|UniProtKB=Q9HAH7 Q9HAH7 FBRS PTHR14429:SF24 FIBROSIN FAMILY MEMBER FIBROSIN-1-RELATED HUMAN|HGNC=4399|UniProtKB=P63244 P63244 RACK1 PTHR19868:SF0 RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1 RECEPTOR OF ACTIVATED PROTEIN C KINASE 1 binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein-containing complex binding#GO:0044877;kinase binding#GO:0019900 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;peptide biosynthetic process#GO:0043043;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;translation#GO:0006412;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytosolic ribosome#GO:0022626;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840 HUMAN|HGNC=28135|UniProtKB=Q9BT92 Q9BT92 TCHP PTHR31183:SF2 TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intracellular#GO:0005622;intermediate filament cytoskeleton#GO:0045111;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 HUMAN|HGNC=33512|UniProtKB=Q56P42 Q56P42 PYDC2 PTHR45690:SF18 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 2-RELATED HUMAN|HGNC=18283|UniProtKB=Q8WXH6 Q8WXH6 RAB40A PTHR47980:SF1 LD44762P RAS-RELATED PROTEIN RAB-40A vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;protein secretion#GO:0009306;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=10898|UniProtKB=Q15477 Q15477 SKIV2L PTHR12131:SF8 ATP-DEPENDENT RNA AND DNA HELICASE HELICASE SKI2W catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 DNA metabolism protein#PC00009 HUMAN|HGNC=10896|UniProtKB=P12755 P12755 SKI PTHR10005:SF15 SKI ONCOGENE-RELATED SKI ONCOGENE cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;nucleobase-containing compound metabolic process#GO:0006139;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;BMP signaling pathway#GO:0030509;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;negative regulation of signal transduction#GO:0009968;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;negative regulation of RNA metabolic process#GO:0051253;response to growth factor#GO:0070848;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of cellular response to transforming growth factor beta stimulus#GO:1903844;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;negative regulation of transforming growth factor beta receptor signaling pathway#GO:0030512;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 HUMAN|HGNC=9561|UniProtKB=P55036 P55036 PSMD4 PTHR10223:SF7 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 cellular component biogenesis#GO:0044085;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein-containing complex assembly#GO:0065003;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;proteasome assembly#GO:0043248;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;cellular protein catabolic process#GO:0044257;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;proteasome regulatory particle, base subcomplex#GO:0008540;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 HUMAN|HGNC=32523|UniProtKB=A8MVU1 A8MVU1 NCF1C PTHR15706:SF6 SH3 MULTIPLE DOMAIN NEUTROPHIL CYTOSOL FACTOR 1-RELATED phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;catalytic activity#GO:0003824;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152 HUMAN|HGNC=18349|UniProtKB=Q13268 Q13268 DHRS2 PTHR43943:SF3 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 2, MITOCHONDRIAL dehydrogenase#PC00092 HUMAN|HGNC=29421|UniProtKB=Q8TF27 Q8TF27 AGAP11 PTHR45819:SF8 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 11 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=1583|UniProtKB=P30279 P30279 CCND2 PTHR10177:SF66 CYCLINS G1/S-SPECIFIC CYCLIN-D2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cell cycle#GO:0045787;positive regulation of cell cycle G1/S phase transition#GO:1902808;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of mitotic cell cycle#GO:0045931;regulation of G1/S transition of mitotic cell cycle#GO:2000045;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of phosphate metabolic process#GO:0019220;regulation of cyclin-dependent protein kinase activity#GO:1904029;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of cell cycle process#GO:0090068;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of protein kinase activity#GO:0045859;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of mitotic cell cycle#GO:0007346;regulation of transferase activity#GO:0051338 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 PI3 kinase pathway#P00048>Cyclin d#G01546;Cell cycle#P00013>Cyclin D#P00484 HUMAN|HGNC=14525|UniProtKB=Q9UHD1 Q9UHD1 CHORDC1 PTHR12621:SF9 CYSTEINE AND HISTIDINE-RICH DOMAIN CHORD -CONTAINING PROTEIN CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29672|UniProtKB=Q8IY33 Q8IY33 MICALL2 PTHR23167:SF53 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED MICAL-LIKE PROTEIN 2 HUMAN|HGNC=32946|UniProtKB=Q5JPF3 Q5JPF3 ANKRD36C PTHR24147:SF50 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 36A-RELATED HUMAN|HGNC=26090|UniProtKB=Q4G0X9 Q4G0X9 CCDC40 PTHR16275:SF8 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 COILED-COIL DOMAIN-CONTAINING PROTEIN 40 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=18069|UniProtKB=Q9UHE5 Q9UHE5 NAT8 PTHR13947:SF14 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE 8-RELATED transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 HUMAN|HGNC=11877|UniProtKB=P57727 P57727 TMPRSS3 PTHR24253:SF86 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 3 serine protease#PC00203 HUMAN|HGNC=41979|UniProtKB=E9PIF3 E9PIF3 NPIPA2 PTHR15438:SF14 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER A1-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=37208|UniProtKB=A6NKL6 A6NKL6 TMEM200C PTHR31815:SF2 AGAP005329-PA TRANSMEMBRANE PROTEIN 200C HUMAN|HGNC=16217|UniProtKB=Q9BZ19 Q9BZ19 ANKRD60 PTHR22677:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60 HUMAN|HGNC=14743|UniProtKB=Q8NH72 Q8NH72 OR4C6 PTHR48002:SF128 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C6 transmembrane signal receptor#PC00197 HUMAN|HGNC=7881|UniProtKB=P46531 P46531 NOTCH1 PTHR45836:SF12 SLIT HOMOLOG NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330;Notch signaling pathway#GO:0007219 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Notch signaling pathway#P00045>Notch#P01099;Angiogenesis#P00005>Notch#P00255;Notch signaling pathway#P00045>NIct#P01119;Alzheimer disease-presenilin pathway#P00004>Notch N-terminal fragment#P00171;Notch signaling pathway#P00045>NIcs#P01120;Notch signaling pathway#P00045>Ntm#P01114;Alzheimer disease-presenilin pathway#P00004>Notch C-terminal fragment#P00120;Notch signaling pathway#P00045>Next#P01103;Alzheimer disease-presenilin pathway#P00004>NICD#P00122;Alzheimer disease-presenilin pathway#P00004>Notch#P00176;Alzheimer disease-presenilin pathway#P00004>Notch fragment#P00154;Alzheimer disease-presenilin pathway#P00004>Notch transmembrane fragment#P00135;Alzheimer disease-presenilin pathway#P00004>Notch extracellular fragment#P00179 HUMAN|HGNC=24348|UniProtKB=Q8IX95 Q8IX95 CTAGE3P PTHR23158:SF55 MELANOMA INHIBITORY ACTIVITY-RELATED CTAGE FAMILY MEMBER 3-RELATED endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=11306|UniProtKB=P78362 P78362 SRPK2 PTHR24055:SF540 MITOGEN-ACTIVATED PROTEIN KINASE SRSF PROTEIN KINASE 2 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;regulation of mRNA processing#GO:0050684;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;signaling#GO:0023052;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=24313|UniProtKB=O95727 O95727 CRTAM PTHR47118:SF1 CYTOTOXIC AND REGULATORY T-CELL MOLECULE CYTOTOXIC AND REGULATORY T-CELL MOLECULE protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 response to external biotic stimulus#GO:0043207;cell recognition#GO:0008037;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;lymphocyte mediated immunity#GO:0002449;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of lymphocyte mediated immunity#GO:0002706;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;positive regulation of immune effector process#GO:0002699;defense response#GO:0006952;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;regulation of response to external stimulus#GO:0032101;immune response#GO:0006955;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;detection of stimulus#GO:0051606;cellular process#GO:0009987;positive regulation of lymphocyte mediated immunity#GO:0002708;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;regulation of response to biotic stimulus#GO:0002831;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=2045|UniProtKB=O15551 O15551 CLDN3 PTHR12002:SF112 CLAUDIN CLAUDIN-3 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=14357|UniProtKB=Q8N119 Q8N119 MMP21 PTHR10201:SF147 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-21 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=11583|UniProtKB=P05543 P05543 SERPINA7 PTHR11461:SF39 SERINE PROTEASE INHIBITOR, SERPIN THYROXINE-BINDING GLOBULIN serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=28302|UniProtKB=Q96CN5 Q96CN5 LRRC45 PTHR23170:SF3 NY-REN-58 ANTIGEN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 45 HUMAN|HGNC=26817|UniProtKB=Q86SG4 Q86SG4 HMGN2P46 PTHR23087:SF27 NONHISTONE CHROMOSOMAL PROTEIN HMG DRESDEN PROSTATE CARCINOMA PROTEIN 2-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=26274|UniProtKB=Q96I59 Q96I59 NARS2 PTHR22594:SF34 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=13209|UniProtKB=Q12774 Q12774 ARHGEF5 PTHR12845:SF2 GUANINE NUCLEOTIDE EXCHANGE FACTOR DH DOMAIN-CONTAINING PROTEIN-RELATED Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=18158|UniProtKB=Q9H322 Q9H322 VCX2 PTHR15251:SF2 TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED HUMAN|HGNC=11967|UniProtKB=Q5SZQ8 Q5SZQ8 CELF3 PTHR24012:SF739 RNA BINDING PROTEIN CUGBP ELAV-LIKE FAMILY MEMBER 3 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29869|UniProtKB=P98077 P98077 SHC2 PTHR10337:SF5 SHC TRANSFORMING PROTEIN SHC-TRANSFORMING PROTEIN 2 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Shc#P00554;Angiogenesis#P00005>Sck#P00202;PDGF signaling pathway#P00047>Shc#P01175;VEGF signaling pathway#P00056>Sck#P01424 HUMAN|HGNC=6096|UniProtKB=A6NM10 A6NM10 AQP12B PTHR21191:SF8 AQUAPORIN AQUAPORIN-12A-RELATED passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=31910|UniProtKB=Q6DN72 Q6DN72 FCRL6 PTHR11481:SF62 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE PROTEIN 6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=26113|UniProtKB=Q2MV58 Q2MV58 TCTN1 PTHR14611:SF1 TECTONIC FAMILY MEMBER TECTONIC-1 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 HUMAN|HGNC=11182|UniProtKB=O75808 O75808 CAPN15 PTHR10183:SF382 CALPAIN CALPAIN-15 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=17163|UniProtKB=Q8NCC3 Q8NCC3 PLA2G15 PTHR11440:SF47 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED PHOSPHOLIPASE A2 GROUP XV hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;triglyceride lipase activity#GO:0004806 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=25835|UniProtKB=Q6ZMP0 Q6ZMP0 THSD4 PTHR13723:SF16 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 4 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=14151|UniProtKB=Q9UJH8 Q9UJH8 METRN PTHR28593:SF2 METEORIN-LIKE PROTEIN METEORIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 cell projection organization#GO:0030030;gliogenesis#GO:0042063;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;positive regulation of cell projection organization#GO:0031346;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;glial cell differentiation#GO:0010001;cell differentiation#GO:0030154;system development#GO:0048731;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;positive regulation of neuron differentiation#GO:0045666;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;generation of neurons#GO:0048699 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=3788|UniProtKB=Q04609 Q04609 FOLH1 PTHR10404:SF36 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153 HUMAN|HGNC=11094|UniProtKB=O43623 O43623 SNAI2 PTHR24388:SF42 ZINC FINGER PROTEIN ZINC FINGER PROTEIN SNAI2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=30862|UniProtKB=O14957 O14957 UQCR11 PTHR15420:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 6.4 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 10 electron transfer activity#GO:0009055;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;ubiquinol-cytochrome-c reductase activity#GO:0008121;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 reductase#PC00198 HUMAN|HGNC=30506|UniProtKB=Q8IVE3 Q8IVE3 PLEKHH2 PTHR22903:SF3 PLEKHH PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 2 HUMAN|HGNC=7223|UniProtKB=P25325 P25325 MPST PTHR11364:SF25 THIOSULFATE SULFERTANSFERASE 3-MERCAPTOPYRUVATE SULFURTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid metabolic process#GO:0006520;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transferase#PC00220 HUMAN|HGNC=1324|UniProtKB=P0C0L5 P0C0L5 C4B_2 PTHR11412:SF86 MACROGLOBULIN / COMPLEMENT COMPLEMENT C4-A-RELATED activation of immune response#GO:0002253;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;humoral immune response#GO:0006959;regulation of immune response#GO:0050776;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;positive regulation of response to stimulus#GO:0048584;immune system process#GO:0002376;response to stimulus#GO:0050896;protein activation cascade#GO:0072376;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;immune effector process#GO:0002252;positive regulation of biological process#GO:0048518;complement activation#GO:0006956;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=8933|UniProtKB=Q8WV24 Q8WV24 PHLDA1 PTHR15478:SF4 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, PQ-RICH PROTEIN PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 1 positive regulation of apoptotic process#GO:0043065;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of cell death#GO:0010942;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 HUMAN|HGNC=23714|UniProtKB=Q6ZNH5 Q6ZNH5 ZNF497 PTHR24404:SF50 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 497 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28466|UniProtKB=Q9BT43 Q9BT43 POLR3GL PTHR15367:SF4 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC7-LIKE membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=16287|UniProtKB=Q9UMS0 Q9UMS0 NFU1 PTHR11178:SF1 IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL HUMAN|HGNC=28571|UniProtKB=Q8IV50 Q8IV50 LYSMD2 PTHR20932:SF4 LOC443603 PROTEIN-RELATED AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 2-RELATED HUMAN|HGNC=37280|UniProtKB=C9JH25 C9JH25 PRRT4 PTHR35578:SF1 PROLINE-RICH TRANSMEMBRANE PROTEIN 4-RELATED PROLINE-RICH TRANSMEMBRANE PROTEIN 4 HUMAN|HGNC=24434|UniProtKB=Q49A26 Q49A26 GLYR1 PTHR43580:SF2 OXIDOREDUCTASE GLYR1-RELATED OXIDOREDUCTASE GLYR1-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidoreductase#PC00176 HUMAN|HGNC=6511|UniProtKB=O95461 O95461 LARGE1 PTHR12270:SF48 GLYCOSYLTRANSFERASE-RELATED LARGE XYLOSYL- AND GLUCURONYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;xylosyltransferase activity#GO:0042285;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 glycosyltransferase#PC00111 HUMAN|HGNC=14248|UniProtKB=Q96RN5 Q96RN5 MED15 PTHR31804:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 HUMAN|HGNC=6872|UniProtKB=P53779 P53779 MAPK10 PTHR24055:SF162 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 10 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;MAPK cascade#GO:0000165;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;JNK cascade#GO:0007254;stress-activated MAPK cascade#GO:0051403;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;stress-activated protein kinase signaling cascade#GO:0031098;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Integrin signalling pathway#P00034>Jnk#P00951;TGF-beta signaling pathway#P00052>JNK#P01284;PDGF signaling pathway#P00047>ERK#P01143;Angiogenesis#P00005>JNK1#P00221;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>JNK1-3#P00545;CCKR signaling map#P06959>MAPK8-10#P07090;FGF signaling pathway#P00021>JNK1-3#P00628;FAS signaling pathway#P00020>JNK#P00615;Integrin signalling pathway#P00034>ERK#P00907;Oxidative stress response#P00046>JNK1/2#P01129;Ras Pathway#P04393>JNK#P04572;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Apoptosis signaling pathway#P00006>JNK#P00274;Toll receptor signaling pathway#P00054>JNK#P01375;B cell activation#P00010>Jnk#P00402;Parkinson disease#P00049>SAPK#P01219;T cell activation#P00053>Jnk#P01336 HUMAN|HGNC=13922|UniProtKB=Q5SRN2 Q5SRN2 TSBP1 PTHR14368:SF7 TESTIS-EXPRESSED BASIC PROTEIN 1 TESTIS-EXPRESSED BASIC PROTEIN 1 HUMAN|HGNC=29394|UniProtKB=Q5GH76 Q5GH76 XKR4 PTHR16024:SF16 XK-RELATED PROTEIN XK-RELATED PROTEIN 4 cellular component biogenesis#GO:0044085;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;developmental process#GO:0032502;endomembrane system organization#GO:0010256;plasma membrane bounded cell projection organization#GO:0120036;lipid transport#GO:0006869;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anion transport#GO:0006820;apoptotic process#GO:0006915;lipid translocation#GO:0034204;cell death#GO:0008219;vesicle organization#GO:0016050;lipid localization#GO:0010876;phospholipid translocation#GO:0045332;cellular component assembly#GO:0022607;organophosphate ester transport#GO:0015748;phagocytosis#GO:0006909;organic anion transport#GO:0015711;ion transport#GO:0006811;endocytosis#GO:0006897;plasma membrane phospholipid scrambling#GO:0017121;vesicle-mediated transport#GO:0016192;programmed cell death#GO:0012501;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;phospholipid transport#GO:0015914;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;anatomical structure development#GO:0048856;biological regulation#GO:0065007;plasma membrane bounded cell projection assembly#GO:0120031;apoptotic cell clearance#GO:0043277 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=2704|UniProtKB=P27707 P27707 DCK PTHR10513:SF19 DEOXYNUCLEOSIDE KINASE DEOXYCYTIDINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotide kinase#PC00172 HUMAN|HGNC=9828|UniProtKB=P78406 P78406 RAE1 PTHR10971:SF11 MRNA EXPORT FACTOR AND BUB3 MRNA EXPORT FACTOR nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;binding#GO:0005488;organic cyclic compound binding#GO:0097159;ubiquitin binding#GO:0043130 cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of RNA localization#GO:0051236;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;RNA localization#GO:0006403;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;organelle organization#GO:0006996;chromosome organization#GO:0051276;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 RNA metabolism protein#PC00031 HUMAN|Ensembl=ENSG00000283528|UniProtKB=A0A1B0GVM2 A0A1B0GVM2 TCAF2C PTHR15730:SF4 EXPERIMENTAL AUTOIMMUNE PROSTATITIS ANTIGEN 2-RELATED PEPTIDASE M60 DOMAIN-CONTAINING PROTEIN-RELATED regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;negative regulation of transport#GO:0051051;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;regulation of ion transmembrane transporter activity#GO:0032412;anion transmembrane transport#GO:0098656;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;anion transport#GO:0006820;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;inorganic anion transport#GO:0015698;negative regulation of molecular function#GO:0044092 HUMAN|HGNC=30676|UniProtKB=Q8WU76 Q8WU76 SCFD2 PTHR11679:SF74 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 2 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=25249|UniProtKB=Q5FWF4 Q5FWF4 ZRANB3 PTHR45766:SF6 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of DNA replication#GO:0008156;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;replication fork processing#GO:0031297;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 pre-replicative complex#GO:0036387;intracellular membrane-bounded organelle#GO:0043231;epsilon DNA polymerase complex#GO:0008622;replisome#GO:0030894;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;replication fork#GO:0005657;membrane-enclosed lumen#GO:0031974;origin recognition complex#GO:0000808;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;DNA replication preinitiation complex#GO:0031261;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;CMG complex#GO:0071162;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 DNA metabolism protein#PC00009 HUMAN|HGNC=13812|UniProtKB=Q9NY64 Q9NY64 SLC2A8 PTHR48021:SF18 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 8 HUMAN|HGNC=6648|UniProtKB=Q6P5Q4 Q6P5Q4 LMOD2 PTHR10901:SF12 TROPOMODULIN LEIOMODIN-2 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=30521|UniProtKB=Q96NT5 Q96NT5 SLC46A1 PTHR23507:SF2 ZGC:174356 PROTON-COUPLED FOLATE TRANSPORTER HUMAN|HGNC=8868|UniProtKB=Q9NQP4 Q9NQP4 PFDN4 PTHR21100:SF9 PREFOLDIN SUBUNIT 4 PREFOLDIN SUBUNIT 4 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=14491|UniProtKB=Q9NQ50 Q9NQ50 MRPL40 PTHR13359:SF2 39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=2712|UniProtKB=Q13561 Q13561 DCTN2 PTHR15346:SF0 DYNACTIN SUBUNIT DYNACTIN SUBUNIT 2 mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156 HUMAN|HGNC=24702|UniProtKB=Q8IV04 Q8IV04 TBC1D10C PTHR22957:SF324 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN CARABIN GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=6524|UniProtKB=P06239 P06239 LCK PTHR24418:SF39 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE LCK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;B cell receptor signaling pathway#GO:0050853;cell population proliferation#GO:0008283;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;immune system development#GO:0002520;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;cellular metabolic process#GO:0044237;cell communication#GO:0007154;T cell differentiation#GO:0030217;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;defense response to other organism#GO:0098542;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;signal transduction#GO:0007165;macromolecule modification#GO:0043412;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;system development#GO:0048731;protein autophosphorylation#GO:0046777;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;lymphocyte activation#GO:0046649;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;protein phosphorylation#GO:0006468;cellular process#GO:0009987;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;lymphocyte differentiation#GO:0030098;peptidyl-tyrosine modification#GO:0018212;T cell activation#GO:0042110;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 Parkinson disease#P00049>Src kinase#P01230;T cell activation#P00053>Lck#P01310 HUMAN|HGNC=6564|UniProtKB=Q08380 Q08380 LGALS3BP PTHR24410:SF16 HL07962P-RELATED GALECTIN-3-BINDING PROTEIN HUMAN|HGNC=20612|UniProtKB=Q9H7E2 Q9H7E2 TDRD3 PTHR13681:SF24 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED TUDOR DOMAIN-CONTAINING PROTEIN 3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=11137|UniProtKB=Q5SXM2 Q5SXM2 SNAPC4 PTHR46621:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 HUMAN|HGNC=16065|UniProtKB=Q9NS18 Q9NS18 GLRX2 PTHR46679:SF1 FAMILY NOT NAMED GLUTAREDOXIN-2, MITOCHONDRIAL HUMAN|HGNC=27696|UniProtKB=Q2TAA2 Q2TAA2 IAH1 PTHR14209:SF19 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG esterase#PC00097 HUMAN|HGNC=14430|UniProtKB=Q8WWT9 Q8WWT9 SLC13A3 PTHR10283:SF62 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;succinate transmembrane transporter activity#GO:0015141;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;dicarboxylic acid transmembrane transporter activity#GO:0005310;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;citrate transport#GO:0015746;anion transmembrane transport#GO:0098656 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=29020|UniProtKB=Q5VYK3 Q5VYK3 ECPAS PTHR23346:SF19 TRANSLATIONAL ACTIVATOR GCN1-RELATED PROTEASOME ADAPTER AND SCAFFOLD PROTEIN ECM29 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25116|UniProtKB=Q7M4L6 Q7M4L6 SHF PTHR15127:SF28 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN F protein binding#GO:0005515;binding#GO:0005488 HUMAN|HGNC=13544|UniProtKB=Q9NRG0 Q9NRG0 CHRAC1 PTHR10252:SF54 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED CHROMATIN ACCESSIBILITY COMPLEX PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=4622|UniProtKB=Q8IYD1 Q8IYD1 GSPT2 PTHR23115:SF119 TRANSLATION FACTOR EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR GTP-BINDING SUBUNIT ERF3B GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111 sulfur compound metabolic process#GO:0006790;cellular protein complex disassembly#GO:0043624;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;translational termination#GO:0006415;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 translation factor#PC00223 HUMAN|HGNC=16077|UniProtKB=Q9NRW4 Q9NRW4 DUSP22 PTHR45948:SF3 DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED DUAL SPECIFICITY PROTEIN PHOSPHATASE 22 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;transforming growth factor beta receptor signaling pathway#GO:0007179;regulation of intracellular signal transduction#GO:1902531;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=29473|UniProtKB=Q9UK33 Q9UK33 ZNF580 PTHR24393:SF54 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 580 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11894|UniProtKB=Q13829 Q13829 TNFAIP1 PTHR11145:SF17 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 2 transferase activity#GO:0016740;Ras GTPase binding#GO:0017016;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;GTP-Rho binding#GO:0017049;small GTPase binding#GO:0031267;catalytic activity, acting on a protein#GO:0140096;Rho GTPase binding#GO:0017048 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;negative regulation of Ras protein signal transduction#GO:0046580;regulation of intracellular signal transduction#GO:1902531;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;negative regulation of small GTPase mediated signal transduction#GO:0051058;catabolic process#GO:0009056;intracellular signal transduction#GO:0035556;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;primary metabolic process#GO:0044238;regulation of small GTPase mediated signal transduction#GO:0051056;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of Ras protein signal transduction#GO:0046578 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15217|UniProtKB=Q6IFG1 Q6IFG1 OR52E8 PTHR26450:SF170 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E8 transmembrane signal receptor#PC00197 HUMAN|HGNC=11148|UniProtKB=Q16658 Q16658 FSCN1 PTHR10551:SF23 FASCIN FASCIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament bundle assembly#GO:0051017;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;intracellular organelle#GO:0043229;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;lamellipodium#GO:0030027;ruffle#GO:0001726;plasma membrane region#GO:0098590;distal axon#GO:0150034;cell projection#GO:0042995;microvillus#GO:0005902;filopodium#GO:0030175;cell projection membrane#GO:0031253;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axon#GO:0030424;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;neuron projection#GO:0043005;cytoskeleton#GO:0005856;growth cone#GO:0030426;site of polarized growth#GO:0030427;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 HUMAN|HGNC=1047|UniProtKB=Q93088 Q93088 BHMT PTHR46120:SF2 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155 HUMAN|HGNC=25625|UniProtKB=Q9NV23 Q9NV23 OLAH PTHR11487:SF0 THIOESTERASE S-ACYL FATTY ACID SYNTHASE THIOESTERASE, MEDIUM CHAIN lipid metabolic process#GO:0006629;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 esterase#PC00097 HUMAN|HGNC=16888|UniProtKB=Q9BPW9 Q9BPW9 DHRS9 PTHR43313:SF15 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 9 dehydrogenase#PC00092 HUMAN|HGNC=29456|UniProtKB=Q5JTV8 Q5JTV8 TOR1AIP1 PTHR18843:SF6 TORSIN-1A-INTERACTING PROTEIN TORSIN-1A-INTERACTING PROTEIN 1 HUMAN|HGNC=9378|UniProtKB=Q9Y478 Q9Y478 PRKAB1 PTHR10343:SF89 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 HUMAN|HGNC=17069|UniProtKB=Q96RU3 Q96RU3 FNBP1 PTHR15735:SF13 FCH AND DOUBLE SH3 DOMAINS PROTEIN FORMIN-BINDING PROTEIN 1 HUMAN|HGNC=4947|UniProtKB=P01903 P01903 HLA-DRA PTHR19944:SF63 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN-RELATED major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 HUMAN|HGNC=3070|UniProtKB=Q13115 Q13115 DUSP4 PTHR10159:SF111 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 4 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;phosphoprotein phosphatase activity#GO:0004721;kinase activity#GO:0016301;kinase binding#GO:0019900;phosphoric ester hydrolase activity#GO:0042578;protein kinase activity#GO:0004672;transferase activity#GO:0016740;MAP kinase activity#GO:0004707;hydrolase activity#GO:0016787;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;ectoderm formation#GO:0001705;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;mesoderm morphogenesis#GO:0048332;intracellular signal transduction#GO:0035556;regulation of MAP kinase activity#GO:0043405;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;ectoderm development#GO:0007398;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;embryo development#GO:0009790;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;mesoderm formation#GO:0001707;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;endoderm formation#GO:0001706;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of MAP kinase activity#GO:0043407;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;mesoderm development#GO:0007498;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;formation of primary germ layer#GO:0001704;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;tissue morphogenesis#GO:0048729;embryonic morphogenesis#GO:0048598;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=6849|UniProtKB=Q02779 Q02779 MAP3K10 PTHR44329:SF39 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 10 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of JNK cascade#GO:0046330;positive regulation of programmed cell death#GO:0043068;regulation of protein serine/threonine kinase activity#GO:0071900;cell death#GO:0008219;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of apoptotic process#GO:0043065;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;regulation of stress-activated MAPK cascade#GO:0032872;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;positive regulation of cell death#GO:0010942;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 non-receptor serine/threonine protein kinase#PC00167 Huntington disease#P00029>MLK-2#P00764;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;p38 MAPK pathway#P05918>MLK2#P06028 HUMAN|HGNC=37248|UniProtKB=B3KS81 B3KS81 SRRM5 PTHR39414:SF1 SERINE/ARGININE REPETITIVE MATRIX PROTEIN 5-RELATED SERINE/ARGININE REPETITIVE MATRIX PROTEIN 5 HUMAN|HGNC=21396|UniProtKB=Q8WTS1 Q8WTS1 ABHD5 PTHR42886:SF34 RE40534P-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5 hydrolase activity#GO:0016787;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;phospholipid biosynthetic process#GO:0008654;regulation of catabolic process#GO:0009894;macromolecule localization#GO:0033036;organophosphate biosynthetic process#GO:0090407;positive regulation of cellular metabolic process#GO:0031325;neutral lipid catabolic process#GO:0046461;positive regulation of cellular catabolic process#GO:0031331;regulation of localization#GO:0032879;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;acylglycerol catabolic process#GO:0046464;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;cellular lipid catabolic process#GO:0044242;positive regulation of biological process#GO:0048518;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;glycerolipid catabolic process#GO:0046503;chemical homeostasis#GO:0048878;cellular process#GO:0009987;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;lipid homeostasis#GO:0055088;organophosphate metabolic process#GO:0019637;regulation of lipid metabolic process#GO:0019216;lipid storage#GO:0019915;cellular lipid metabolic process#GO:0044255;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29070|UniProtKB=Q96QE4 Q96QE4 LRRC37B PTHR23045:SF9 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37B-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=13352|UniProtKB=Q9GZQ8 Q9GZQ8 MAP1LC3B PTHR10969:SF15 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3 BETA 2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;whole membrane#GO:0098805 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=3588|UniProtKB=O15287 O15287 FANCG PTHR15254:SF2 FANCONI ANEMIA GROUP G PROTEIN FAMILY MEMBER FANCONI ANEMIA GROUP G PROTEIN response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to DNA damage stimulus#GO:0006974;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;Fanconi anaemia nuclear complex#GO:0043240;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=24253|UniProtKB=Q9Y3B3 Q9Y3B3 TMED7 PTHR22811:SF117 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TIR DOMAIN-CONTAINING ADAPTER MOLECULE 2-RELATED endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 Toll receptor signaling pathway#P00054>TRIF#P01344 HUMAN|HGNC=25439|UniProtKB=Q6ICL3 Q6ICL3 TANGO2 PTHR17985:SF8 SER/THR-RICH PROTEIN T10 IN DGCR REGION TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG HUMAN|HGNC=17017|UniProtKB=P62312 P62312 LSM6 PTHR11021:SF1 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 small nucleolar ribonucleoprotein complex#GO:0005732;membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;U6 snRNP#GO:0005688;organelle lumen#GO:0043233;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;U5 snRNP#GO:0005682;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=30703|UniProtKB=Q8NEL0 Q8NEL0 CCDC54 PTHR37880:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 54 COILED-COIL DOMAIN-CONTAINING PROTEIN 54 HUMAN|HGNC=24314|UniProtKB=Q96DZ5 Q96DZ5 CLIP3 PTHR18916:SF77 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 chaperone#PC00072 HUMAN|HGNC=14085|UniProtKB=Q9NQC3 Q9NQC3 RTN4 PTHR45799:SF1 RETICULON-LIKE PROTEIN RETICULON-4 HUMAN|HGNC=15831|UniProtKB=P81877 P81877 SSBP2 PTHR12610:SF23 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 2 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 HUMAN|HGNC=23030|UniProtKB=Q8N8U2 Q8N8U2 CDYL2 PTHR43684:SF2 FAMILY NOT NAMED CHROMODOMAIN Y-LIKE PROTEIN 2 transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=16157|UniProtKB=Q96MP5 Q96MP5 ZSWIM3 PTHR31569:SF3 SWIM-TYPE DOMAIN-CONTAINING PROTEIN ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=24659|UniProtKB=Q8IYI6 Q8IYI6 EXOC8 PTHR21426:SF12 EXOCYST COMPLEX COMPONENT 8 EXOCYST COMPLEX COMPONENT 8 localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 HUMAN|HGNC=9539|UniProtKB=P49721 P49721 PSMB2 PTHR11599:SF6 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-2 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 HUMAN|HGNC=13819|UniProtKB=Q9NYB5 Q9NYB5 SLCO1C1 PTHR11388:SF99 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1C1 secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=53903|UniProtKB=A0A2R8YFM6 A0A2R8YFM6 OOSP3 PTHR14380:SF10 PLACENTA-SPECIFIC PROTEIN 1 OOCYTE-SECRETED PROTEIN 3 HUMAN|HGNC=9504|UniProtKB=O43739 O43739 CYTH3 PTHR10663:SF320 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-3 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=25948|UniProtKB=Q7Z4H7 Q7Z4H7 HAUS6 PTHR16151:SF2 UNCHARACTERIZED HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6 HUMAN|HGNC=15868|UniProtKB=Q8N2K0 Q8N2K0 ABHD12 PTHR12277:SF61 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN LYSOPHOSPHATIDYLSERINE LIPASE ABHD12 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;acylglycerol lipase activity#GO:0047372;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;acylglycerol catabolic process#GO:0046464;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 serine protease#PC00203 HUMAN|HGNC=16978|UniProtKB=Q14507 Q14507 EDDM3A PTHR16788:SF4 EPIDIDYMAL SECRETORY PROTEIN E3 ALPHA EPIDIDYMAL SECRETORY PROTEIN E3-ALPHA HUMAN|HGNC=40038|UniProtKB=P0DJ07 P0DJ07 PET100 PTHR33968:SF1 PROTEIN PET100 HOMOLOG, MITOCHONDRIAL PROTEIN PET100 HOMOLOG, MITOCHONDRIAL protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=9972|UniProtKB=P35249 P35249 RFC4 PTHR11669:SF20 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 4 pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;replication fork#GO:0005657 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 HUMAN|HGNC=23114|UniProtKB=P55199 P55199 ELL PTHR23288:SF9 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL general transcription factor#PC00259 HUMAN|HGNC=18015|UniProtKB=Q9NRM6 Q9NRM6 IL17RB PTHR15583:SF11 INTERLEUKIN-17 RECEPTOR INTERLEUKIN-17 RECEPTOR B signaling receptor activity#GO:0038023;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;cytokine binding#GO:0019955 transmembrane signal receptor#PC00197 HUMAN|HGNC=30682|UniProtKB=Q8N3D4 Q8N3D4 EHBP1L1 PTHR23167:SF42 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED EH DOMAIN-BINDING PROTEIN 1-LIKE PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856 HUMAN|HGNC=9605|UniProtKB=P35354 P35354 PTGS2 PTHR11903:SF8 PROSTAGLANDIN G/H SYNTHASE PROSTAGLANDIN G/H SYNTHASE 2 oxygenase#PC00177 CCKR signaling map#P06959>COX2#G07292;Endothelin signaling pathway#P00019>COX-2#P00582;Toll receptor signaling pathway#P00054>Gene trancription#G01550;CCKR signaling map#P06959>COX2#P07080;CCKR signaling map#P06959>COX2#G06998;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cyclooxygenase#P00845 HUMAN|HGNC=14220|UniProtKB=Q96P63 Q96P63 SERPINB12 PTHR11461:SF125 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B12 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=17992|UniProtKB=Q9HCF6 Q9HCF6 TRPM3 PTHR13800:SF7 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=9974|UniProtKB=Q9Y644 Q9Y644 RFNG PTHR10811:SF1 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE RADICAL FRINGE transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of Notch signaling pathway#GO:0008593;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signaling#GO:0023052;Notch signaling pathway#GO:0007219 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Fringe#P01107 HUMAN|HGNC=7112|UniProtKB=Q9UHC7 Q9UHC7 MKRN1 PTHR11224:SF37 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-1 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=5855|UniProtKB=P0CG04 P0CG04 IGLC1 PTHR23266:SF310 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN LAMBDA CONSTANT 1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=17021|UniProtKB=O75129 O75129 ASTN2 PTHR16592:SF2 FAMILY NOT NAMED ASTROTACTIN-2 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;developmental process#GO:0032502;localization of cell#GO:0051674;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;nervous system development#GO:0007399;localization#GO:0051179;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron migration#GO:0001764;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477;locomotion#GO:0040011 HUMAN|HGNC=678|UniProtKB=P52565 P52565 ARHGDIA PTHR10980:SF9 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rho GTPase binding#GO:0017048;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;Rac GTPase binding#GO:0048365;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;Rho protein signal transduction#GO:0007266 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 G-protein modulator#PC00022 HUMAN|HGNC=3004|UniProtKB=Q9BQC3 Q9BQC3 DPH2 PTHR10762:SF2 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=22980|UniProtKB=Q96EP9 Q96EP9 SLC10A4 PTHR10361:SF41 SODIUM-BILE ACID COTRANSPORTER SODIUM/BILE ACID COTRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068 HUMAN|HGNC=17129|UniProtKB=Q6P5W5 Q6P5W5 SLC39A4 PTHR12191:SF21 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP4 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=7154|UniProtKB=P08473 P08473 MME PTHR11733:SF114 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN metalloprotease#PC00153 HUMAN|HGNC=1869|UniProtKB=P11597 P11597 CETP PTHR47616:SF1 CHOLESTERYL ESTER TRANSFER PROTEIN CHOLESTERYL ESTER TRANSFER PROTEIN cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;sterol binding#GO:0032934;steroid binding#GO:0005496;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;cholesterol binding#GO:0015485 sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;triglyceride homeostasis#GO:0070328;macromolecule localization#GO:0033036;transport#GO:0006810;cholesterol metabolic process#GO:0008203;phospholipid metabolic process#GO:0006644;acylglycerol metabolic process#GO:0006639;lipid transport#GO:0006869;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;glycerolipid metabolic process#GO:0046486;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;lipid localization#GO:0010876;secondary alcohol metabolic process#GO:1902652;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;triglyceride metabolic process#GO:0006641;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;alcohol metabolic process#GO:0006066;glycerophospholipid metabolic process#GO:0006650;cellular component organization#GO:0016043;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cholesterol homeostasis#GO:0042632;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;high-density lipoprotein particle#GO:0034364;extracellular region#GO:0005576 CCKR signaling map#P06959>CETP#P07189 HUMAN|HGNC=23727|UniProtKB=Q86Y37 Q86Y37 CACUL1 PTHR46636:SF1 CDK2-ASSOCIATED AND CULLIN DOMAIN-CONTAINING PROTEIN 1 CDK2-ASSOCIATED AND CULLIN DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=12540|UniProtKB=Q9HAW9 Q9HAW9 UGT1A8 PTHR48050:SF6 STEROL 3-BETA-GLUCOSYLTRANSFERASE UDP-GLUCURONOSYLTRANSFERASE 1A10-RELATED glycosyltransferase#PC00111 HUMAN|HGNC=13658|UniProtKB=Q9HB63 Q9HB63 NTN4 PTHR10574:SF282 NETRIN/LAMININ-RELATED NETRIN-4 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cell morphogenesis involved in differentiation#GO:0000904;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;substrate adhesion-dependent cell spreading#GO:0034446;localization of cell#GO:0051674;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;extracellular matrix organization#GO:0030198;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;cell differentiation#GO:0030154;extracellular structure organization#GO:0043062;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;cell migration#GO:0016477;locomotion#GO:0040011 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=18430|UniProtKB=Q96A28 Q96A28 SLAMF9 PTHR12080:SF18 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SLAM FAMILY MEMBER 9 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=6938|UniProtKB=Q9GZX3 Q9GZX3 CHST6 PTHR10704:SF4 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 6 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;sulfur compound metabolic process#GO:0006790;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;amino sugar metabolic process#GO:0006040;aminoglycan metabolic process#GO:0006022;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=13596|UniProtKB=Q8TCJ0 Q8TCJ0 FBXO25 PTHR13123:SF8 LD30288P F-BOX ONLY PROTEIN 25 HUMAN|HGNC=32326|UniProtKB=Q9UPX0 Q9UPX0 IGSF9B PTHR12231:SF240 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN PROTEIN TURTLE HOMOLOG B neuron projection#GO:0043005;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=6515|UniProtKB=Q9NRM7 Q9NRM7 LATS2 PTHR24356:SF149 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE LATS2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;cell cycle process#GO:0022402;growth#GO:0040007;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of growth#GO:0040008;mitotic cell cycle process#GO:1903047;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;positive regulation of programmed cell death#GO:0043068;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;cell death#GO:0008219;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;regulation of apoptotic process#GO:0042981;developmental growth#GO:0048589;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;hippo signaling#GO:0035329;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell cycle#GO:0007049;peptidyl-serine modification#GO:0018209;multicellular organismal process#GO:0032501;organelle fission#GO:0048285;positive regulation of cell death#GO:0010942 intracellular non-membrane-bounded organelle#GO:0043232;spindle pole#GO:0000922;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=9250|UniProtKB=Q8ND30 Q8ND30 PPFIBP2 PTHR12587:SF18 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-BETA-2 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330;neuromuscular junction development#GO:0007528 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 HUMAN|HGNC=33595|UniProtKB=A6NLU5 A6NLU5 VSTM2B PTHR12207:SF27 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2B intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=4165|UniProtKB=P54826 P54826 GAS1 PTHR16840:SF3 GROWTH ARREST-SPECIFIC PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 1 HUMAN|HGNC=896|UniProtKB=P47901 P47901 AVPR1B PTHR24241:SF18 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V1B RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;system process#GO:0003008;regulation of blood vessel diameter#GO:0097746;regulation of system process#GO:0044057;regulation of systemic arterial blood pressure#GO:0003073;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of multicellular organismal process#GO:0051240 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=25055|UniProtKB=Q9H4I9 Q9H4I9 SMDT1 PTHR33904:SF1 ESSENTIAL MCU REGULATOR, MITOCHONDRIAL ESSENTIAL MCU REGULATOR, MITOCHONDRIAL cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;mitochondrial calcium ion homeostasis#GO:0051560;mitochondrial transmembrane transport#GO:1990542;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;mitochondrial transport#GO:0006839;cellular chemical homeostasis#GO:0055082;mitochondrial calcium ion transmembrane transport#GO:0006851;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 integral component of mitochondrial inner membrane#GO:0031305;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;intrinsic component of mitochondrial inner membrane#GO:0031304;ion channel complex#GO:0034702;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;membrane#GO:0016020;cation channel complex#GO:0034703;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of mitochondrial membrane#GO:0098573;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=2883|UniProtKB=P49895 P49895 DIO1 PTHR11781:SF22 IODOTHYRONINE DEIODINASE TYPE I IODOTHYRONINE DEIODINASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=26460|UniProtKB=Q96N16 Q96N16 JAKMIP1 PTHR18935:SF6 UNCHARACTERIZED JANUS KINASE AND MICROTUBULE-INTERACTING PROTEIN 1 HUMAN|HGNC=639|UniProtKB=Q13520 Q13520 AQP6 PTHR19139:SF113 AQUAPORIN TRANSPORTER AQUAPORIN-6 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;nitrate transmembrane transporter activity#GO:0015112;ion transmembrane transporter activity#GO:0015075;inorganic anion transmembrane transporter activity#GO:0015103;channel activity#GO:0015267;transporter activity#GO:0005215 intrinsic component of membrane#GO:0031224;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=25441|UniProtKB=Q6YI46 Q6YI46 TMEM64 PTHR46593:SF1 TRANSMEMBRANE PROTEIN 64 TRANSMEMBRANE PROTEIN 64 HUMAN|HGNC=2567|UniProtKB=O75665 O75665 OFD1 PTHR15431:SF14 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN ORAL-FACIAL-DIGITAL SYNDROME 1 PROTEIN intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=20947|UniProtKB=Q15388 Q15388 TOMM20 PTHR12430:SF2 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG signal sequence binding#GO:0005048;transmembrane transporter activity#GO:0022857;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;amide transmembrane transporter activity#GO:0042887;protein transmembrane transporter activity#GO:0008320;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein-containing complex assembly#GO:0065003;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;RNA transport#GO:0050658;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;transmembrane transport#GO:0055085;establishment of RNA localization#GO:0051236;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;mitochondrial outer membrane translocase complex assembly#GO:0070096;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 bounding membrane of organelle#GO:0098588;mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;intrinsic component of mitochondrial membrane#GO:0098573;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;integral component of mitochondrial outer membrane#GO:0031307 primary active transporter#PC00068 HUMAN|HGNC=12033|UniProtKB=Q13114 Q13114 TRAF3 PTHR10131:SF76 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 3 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625;tumor necrosis factor receptor binding#GO:0005164;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of MAPK cascade#GO:0043408;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;positive regulation of protein modification process#GO:0031401;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;stress-activated MAPK cascade#GO:0051403;cellular protein metabolic process#GO:0044267;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of DNA-binding transcription factor activity#GO:0051091;positive regulation of protein metabolic process#GO:0051247;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;regulation of nucleic acid-templated transcription#GO:1903506;negative regulation of molecular function#GO:0044092;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;transcription, DNA-templated#GO:0006351;regulation of JNK cascade#GO:0046328;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;JNK cascade#GO:0007254;positive regulation of signaling#GO:0023056;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;tumor necrosis factor-mediated signaling pathway#GO:0033209;RNA biosynthetic process#GO:0032774;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of stress-activated MAPK cascade#GO:0032874;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of stress-activated protein kinase signaling cascade#GO:0070302;cellular macromolecule biosynthetic process#GO:0034645;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of stress-activated MAPK cascade#GO:0032872;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;protein K63-linked ubiquitination#GO:0070534;negative regulation of DNA-binding transcription factor activity#GO:0043433 membrane protein complex#GO:0098796;receptor complex#GO:0043235;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25759|UniProtKB=Q49AM3 Q49AM3 TTC31 PTHR47678:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 31 TETRATRICOPEPTIDE REPEAT PROTEIN 31 HUMAN|HGNC=12142|UniProtKB=A0A0B4J266 A0A0B4J266 TRAV41 PTHR19339:SF0 T CELL RECEPTOR ALPHA VARIABLE 39 T CELL RECEPTOR ALPHA VARIABLE 41 HUMAN|HGNC=4415|UniProtKB=Q14749 Q14749 GNMT PTHR16458:SF2 GLYCINE N-METHYLTRANSFERASE GLYCINE N-METHYLTRANSFERASE amino acid binding#GO:0016597;N-methyltransferase activity#GO:0008170;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;cation binding#GO:0043169;transferase activity#GO:0016740;carboxylic acid binding#GO:0031406;identical protein binding#GO:0042802;protein binding#GO:0005515;transferase activity, transferring one-carbon groups#GO:0016741;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;purine-containing compound metabolic process#GO:0072521;carbohydrate metabolic process#GO:0005975;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;oxoacid metabolic process#GO:0043436;carbohydrate biosynthetic process#GO:0016051;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glucose metabolic process#GO:0006006;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;regulation of glucose metabolic process#GO:0010906;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;cellular carbohydrate metabolic process#GO:0044262;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;regulation of metabolic process#GO:0019222;nucleobase-containing small molecule metabolic process#GO:0055086;regulation of cellular metabolic process#GO:0031323;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 methyltransferase#PC00155 HUMAN|HGNC=27867|UniProtKB=P0C1H6 P0C1H6 H2BW2 PTHR23428:SF330 HISTONE H2B HISTONE H2B TYPE F-M nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=23317|UniProtKB=P61647 P61647 ST8SIA6 PTHR11987:SF29 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8F transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=6115|UniProtKB=P48200 P48200 IREB2 PTHR11670:SF31 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER IRON-RESPONSIVE ELEMENT-BINDING PROTEIN 2 carbon-oxygen lyase activity#GO:0016835;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;4 iron, 4 sulfur cluster binding#GO:0051539;metal cluster binding#GO:0051540;iron-sulfur cluster binding#GO:0051536;hydro-lyase activity#GO:0016836;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 HUMAN|HGNC=33451|UniProtKB=Q6PK04 Q6PK04 CCDC137 PTHR21838:SF2 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 137 HUMAN|HGNC=1319|UniProtKB=Q16581 Q16581 C3AR1 PTHR24225:SF28 CHEMOTACTIC RECEPTOR C3A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR complement binding#GO:0001848;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;immune response-regulating signaling pathway#GO:0002764;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;activation of immune response#GO:0002253;divalent inorganic cation homeostasis#GO:0072507;regulation of lipase activity#GO:0060191;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;immune response-activating signal transduction#GO:0002757;activation of phospholipase C activity#GO:0007202;regulation of immune system process#GO:0002682;regulation of hydrolase activity#GO:0051336;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;cellular cation homeostasis#GO:0030003;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;regulation of immune response#GO:0050776;positive regulation of phospholipase activity#GO:0010518;positive regulation of immune system process#GO:0002684;homeostatic process#GO:0042592;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;metal ion homeostasis#GO:0055065 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=16768|UniProtKB=O60391 O60391 GRIN3B PTHR18966:SF364 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3B amino acid binding#GO:0016597;cation channel activity#GO:0005261;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;neurotransmitter receptor activity#GO:0030594;voltage-gated cation channel activity#GO:0022843;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;glutamate binding#GO:0016595;ligand-gated channel activity#GO:0022834 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;ionotropic glutamate receptor signaling pathway#GO:0035235;cellular process#GO:0009987;signaling#GO:0023052;glutamate receptor signaling pathway#GO:0007215 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Ionotropic glutamate receptor pathway#P00037>NR3#P01009;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 HUMAN|HGNC=9309|UniProtKB=Q15172 Q15172 PPP2R5A PTHR10257:SF6 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT ALPHA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;protein autophosphorylation#GO:0046777;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 HUMAN|HGNC=38137|UniProtKB=P60608 P60608 ERVFC1-1 PTHR10424:SF73 VIRAL ENVELOPE PROTEIN ENDOGENOUS RETROVIRUS GROUP FC1 MEMBER 1 ENV POLYPROTEIN viral or transposable element protein#PC00237 HUMAN|HGNC=1510|UniProtKB=Q9UKL3 Q9UKL3 CASP8AP2 PTHR15489:SF2 CASPASE 8 ASSOCIATED PROTEIN 2 CASP8-ASSOCIATED PROTEIN 2 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of proteolysis#GO:0045862;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;regulation of cellular process#GO:0050794;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;signal transduction#GO:0007165;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of metabolic process#GO:0009893;positive regulation of programmed cell death#GO:0043068;cell death#GO:0008219;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell death#GO:0010942 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;PML body#GO:0016605 protein-binding activity modulator#PC00095 HUMAN|HGNC=14439|UniProtKB=Q96Q35 Q96Q35 FLACC1 PTHR21707:SF42 UNCHARACTERIZED FLAGELLUM-ASSOCIATED COILED-COIL DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=11658|UniProtKB=Q8WWU5 Q8WWU5 TCP11 PTHR12832:SF14 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11 HOMOLOG male gamete generation#GO:0048232;signal transduction#GO:0007165;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;spermatid differentiation#GO:0048515;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;spermatogenesis#GO:0007283;reproductive process#GO:0022414;regulation of multi-organism process#GO:0043900;intracellular signal transduction#GO:0035556;multi-organism reproductive process#GO:0044703;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609;sperm capacitation#GO:0048240;germ cell development#GO:0007281;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;gamete generation#GO:0007276;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;multicellular organism reproduction#GO:0032504;cell communication#GO:0007154;regulation of reproductive process#GO:2000241;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;response to stimulus#GO:0050896;reproduction#GO:0000003;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 supramolecular complex#GO:0099080;axoneme#GO:0005930;acrosomal vesicle#GO:0001669;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;cytoplasmic microtubule#GO:0005881;vacuole#GO:0005773;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;B axonemal microtubule#GO:0097650;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;intracellular vesicle#GO:0097708;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;cytoplasmic vesicle#GO:0031410;dynein complex#GO:0030286;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=29112|UniProtKB=Q6DN90 Q6DN90 IQSEC1 PTHR10663:SF327 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=11051|UniProtKB=Q9Y345 Q9Y345 SLC6A5 PTHR11616:SF241 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 2 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=256|UniProtKB=P40394 P40394 ADH7 PTHR43880:SF2 ALCOHOL DEHYDROGENASE ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH7 cation binding#GO:0043169;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 response to organic substance#GO:0010033;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=19095|UniProtKB=Q96CN9 Q96CN9 GCC1 PTHR23157:SF25 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=19412|UniProtKB=O75800 O75800 ZMYND10 PTHR13244:SF7 ZINC FINGER MYND DOMAIN CONTAINING PROTEIN 10 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 10 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=5240|UniProtKB=P48741 P48741 HSPA7 PTHR19375:SF459 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN 7-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524;ATPase activity#GO:0016887 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;chaperone-mediated protein folding#GO:0061077;cellular response to organic substance#GO:0071310;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;'de novo' protein folding#GO:0006458;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;COP9 signalosome#GO:0008180;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=5350|UniProtKB=O60725 O60725 ICMT PTHR12714:SF9 PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE protein modifying enzyme#PC00260 HUMAN|HGNC=29415|UniProtKB=Q8TF50 Q8TF50 ZNF526 PTHR24377:SF770 IP01015P-RELATED ZINC FINGER PROTEIN 526 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=20274|UniProtKB=Q9BY43 Q9BY43 CHMP4A PTHR22761:SF14 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4A endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;leaflet of membrane bilayer#GO:0097478;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562 membrane traffic protein#PC00150 HUMAN|HGNC=29037|UniProtKB=O75038 O75038 PLCH2 PTHR10336:SF166 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ETA-2 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 phospholipase#PC00186 HUMAN|HGNC=25918|UniProtKB=Q969W3 Q969W3 FAM104A PTHR34763:SF1 PROTEIN FAM104A PROTEIN FAM104A HUMAN|HGNC=6968|UniProtKB=Q9UBS3 Q9UBS3 DNAJB9 PTHR44360:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 chaperone#PC00072 HUMAN|HGNC=18277|UniProtKB=P60059 P60059 SEC61G PTHR12309:SF5 SEC61 GAMMA SUBUNIT PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA amide transmembrane transporter activity#GO:0042887;protein transmembrane transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;posttranslational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;rough endoplasmic reticulum membrane#GO:0030867;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;rough endoplasmic reticulum#GO:0005791;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 primary active transporter#PC00068 HUMAN|HGNC=13139|UniProtKB=P17097 P17097 ZNF7 PTHR24377:SF189 IP01015P-RELATED ZINC FINGER PROTEIN 7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26338|UniProtKB=Q6ZMY3 Q6ZMY3 SPOCD1 PTHR11477:SF18 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN SPOC DOMAIN-CONTAINING PROTEIN 1 general transcription factor#PC00259 HUMAN|HGNC=1473|UniProtKB=P27824 P27824 CANX PTHR11073:SF11 CALRETICULIN AND CALNEXIN CALNEXIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;protein folding#GO:0006457;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;response to unfolded protein#GO:0006986;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 chaperone#PC00072 HUMAN|HGNC=9183|UniProtKB=Q9UBT6 Q9UBT6 POLK PTHR11076:SF33 DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER DNA POLYMERASE KAPPA transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;DNA polymerase activity#GO:0034061;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009 HUMAN|HGNC=7393|UniProtKB=P04731 P04731 MT1A PTHR23299:SF49 METALLOTHIONEIN METALLOTHIONEIN-1A cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;transition metal ion homeostasis#GO:0055076;response to metal ion#GO:0010038;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;response to toxic substance#GO:0009636;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12718|UniProtKB=Q99986 Q99986 VRK1 PTHR11909:SF78 CASEIN KINASE-RELATED SERINE/THREONINE-PROTEIN KINASE VRK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;transport#GO:0006810;positive regulation of proteasomal protein catabolic process#GO:1901800;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of protein catabolic process#GO:0042176;positive regulation of Wnt signaling pathway#GO:0030177;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;vesicle organization#GO:0016050;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;canonical Wnt signaling pathway#GO:0060070;regulation of cellular protein catabolic process#GO:1903362;signaling#GO:0023052;cell-cell signaling#GO:0007267;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;Wnt signaling pathway#GO:0016055;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;vesicle budding from membrane#GO:0006900;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=9535|UniProtKB=P60900 P60900 PSMA6 PTHR11599:SF11 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-6 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome core complex, alpha-subunit complex#GO:0019773;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=8898|UniProtKB=P07205 P07205 PGK2 PTHR11406:SF10 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE 2 nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;small molecule binding#GO:0036094;organic cyclic compound binding#GO:0097159;binding#GO:0005488;catalytic activity#GO:0003824;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524;kinase activity#GO:0016301 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;purine nucleoside diphosphate metabolic process#GO:0009135;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;positive regulation of cellular metabolic process#GO:0031325;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ATP generation from ADP#GO:0006757;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;oxidation-reduction process#GO:0055114;purine-containing compound metabolic process#GO:0072521;positive regulation of biological process#GO:0048518;ribonucleoside diphosphate metabolic process#GO:0009185;organic substance metabolic process#GO:0071704;purine nucleotide metabolic process#GO:0006163;purine ribonucleoside diphosphate metabolic process#GO:0009179;purine nucleoside triphosphate biosynthetic process#GO:0009145;oxoacid metabolic process#GO:0043436;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;nucleotide phosphorylation#GO:0046939;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;nucleoside diphosphate phosphorylation#GO:0006165;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;organic acid metabolic process#GO:0006082;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;positive regulation of phosphate metabolic process#GO:0045937;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;glycolytic process#GO:0006096;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;regulation of phosphate metabolic process#GO:0019220;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;cation transport#GO:0006812;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;heterocycle metabolic process#GO:0046483;positive regulation of phosphorylation#GO:0042327;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ADP metabolic process#GO:0046031;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;glucose metabolic process#GO:0006006;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;biological regulation#GO:0065007;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;carboxylic acid metabolic process#GO:0019752;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;B axonemal microtubule#GO:0097650;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;extracellular region#GO:0005576;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;extracellular space#GO:0005615;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;membrane-bounded organelle#GO:0043227;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;axonemal microtubule#GO:0005879 carbohydrate kinase#PC00065 HUMAN|HGNC=16116|UniProtKB=Q9BR26 Q9BR26 OCSTAMP PTHR21041:SF3 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN OSTEOCLAST STIMULATORY TRANSMEMBRANE PROTEIN HUMAN|HGNC=17800|UniProtKB=Q9NSD9 Q9NSD9 FARSB PTHR10947:SF0 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 PHENYLALANINE--TRNA LIGASE BETA SUBUNIT cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=21062|UniProtKB=O95363 O95363 FARS2 PTHR11538:SF41 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=14027|UniProtKB=Q9NYK5 Q9NYK5 MRPL39 PTHR42753:SF9 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER 39S RIBOSOMAL PROTEIN L39, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a tRNA#GO:0140101;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=5882|UniProtKB=P01701 P01701 IGLV1-51 PTHR23267:SF470 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 1-51 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=24088|UniProtKB=Q9HAU6 Q9HAU6 TPT1P8 PTHR11991:SF12 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN-LIKE PROTEIN TPT1P8-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=10890|UniProtKB=Q9UIU6 Q9UIU6 SIX4 PTHR10390:SF36 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 HUMAN|HGNC=16691|UniProtKB=Q9UGJ1 Q9UGJ1 TUBGCP4 PTHR19302:SF27 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;reproductive process#GO:0022414;spindle assembly#GO:0051225;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cytoplasmic microtubule organization#GO:0031122;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;protein polymerization#GO:0051258;organelle fission#GO:0048285;cell cycle#GO:0007049 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;intracellular#GO:0005622;gamma-tubulin complex#GO:0000930;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=33100|UniProtKB=Q8TED1 Q8TED1 GPX8 PTHR11592:SF7 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 8-RELATED oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180 HUMAN|HGNC=7953|UniProtKB=P47972 P47972 NPTX2 PTHR19277:SF1 PENTRAXIN NEURONAL PENTRAXIN-2 HUMAN|HGNC=24215|UniProtKB=Q9HD20 Q9HD20 ATP13A1 PTHR45630:SF7 CATION-TRANSPORTING ATPASE-RELATED MANGANESE-TRANSPORTING ATPASE 13A1 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 HUMAN|HGNC=10381|UniProtKB=P04843 P04843 RPN1 PTHR21049:SF0 RIBOPHORIN I DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;oligosaccharyltransferase complex#GO:0008250;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 HUMAN|HGNC=19597|UniProtKB=Q9H2C8 Q9H2C8 OR51V1 PTHR26450:SF67 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51V1 transmembrane signal receptor#PC00197 HUMAN|HGNC=29382|UniProtKB=Q5JV73 Q5JV73 FRMPD3 PTHR46221:SF1 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=10601|UniProtKB=P51172 P51172 SCNN1D PTHR11690:SF132 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT DELTA cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=33782|UniProtKB=Q6GMV3 Q6GMV3 PTRHD1 PTHR46194:SF1 PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED HUMAN|HGNC=29441|UniProtKB=Q8NI77 Q8NI77 KIF18A PTHR24115:SF399 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF18A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;ATP-dependent microtubule motor activity, plus-end-directed#GO:0008574;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 nuclear chromosome segregation#GO:0098813;protein-containing complex disassembly#GO:0032984;cellular protein complex disassembly#GO:0043624;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;microtubule depolymerization#GO:0007019;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;cellular component disassembly#GO:0022411;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;supramolecular fiber organization#GO:0097435;movement of cell or subcellular component#GO:0006928;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;protein-containing complex subunit organization#GO:0043933 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle midzone#GO:1990023;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=16125|UniProtKB=Q9H579 Q9H579 MROH8 PTHR23120:SF18 MAESTRO-RELATED HEAT DOMAIN-CONTAINING PROTEIN MROH8 HUMAN|HGNC=25576|UniProtKB=Q8IW45 Q8IW45 NAXD PTHR12592:SF0 ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE cellular metabolic process#GO:0044237;cellular process#GO:0009987;metabolic process#GO:0008152 dehydratase#PC00091 HUMAN|HGNC=17306|UniProtKB=Q9HBM6 Q9HBM6 TAF9B PTHR48068:SF5 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 9B transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;RNA polymerase II general transcription initiation factor activity#GO:0016251 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;histone H3 acetylation#GO:0043966;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear lumen#GO:0031981 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=15008|UniProtKB=Q8NGZ4 Q8NGZ4 OR2G3 PTHR26453:SF674 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2G3 transmembrane signal receptor#PC00197 HUMAN|HGNC=10618|UniProtKB=P13500 P13500 CCL2 PTHR12015:SF98 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 2 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=5887|UniProtKB=P01706 P01706 IGLV2-11 PTHR23267:SF473 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 2-11 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=5309|UniProtKB=O60921 O60921 HUS1 PTHR12900:SF4 MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 CHECKPOINT PROTEIN HUS1 DNA repair#GO:0006281;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;reproductive process#GO:0022414;organic substance metabolic process#GO:0071704;nucleotide-excision repair#GO:0006289;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;mitotic DNA integrity checkpoint#GO:0044774;cell cycle phase transition#GO:0044770;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;response to stress#GO:0006950;reproduction#GO:0000003;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;cellular response to stress#GO:0033554;cell cycle G2/M phase transition#GO:0044839;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;double-strand break repair#GO:0006302;mitotic cell cycle phase transition#GO:0044772;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;intra-S DNA damage checkpoint#GO:0031573;mitotic cell cycle process#GO:1903047;telomere maintenance#GO:0000723;mitotic DNA replication checkpoint#GO:0033314;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;mitotic DNA damage checkpoint#GO:0044773;homeostatic process#GO:0042592;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA replication checkpoint#GO:0000076;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 HUMAN|HGNC=14005|UniProtKB=Q86TG7 Q86TG7 PEG10 PTHR15503:SF11 LDOC1 RELATED RETROTRANSPOSON-DERIVED PROTEIN PEG10 HUMAN|HGNC=3359|UniProtKB=Q9Y6X5 Q9Y6X5 ENPP4 PTHR10151:SF79 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE BIS(5'-ADENOSYL)-TRIPHOSPHATASE ENPP4 HUMAN|HGNC=2976|UniProtKB=P26358 P26358 DNMT1 PTHR10629:SF52 CYTOSINE-SPECIFIC METHYLTRANSFERASE DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 DNA methyltransferase#PC00013 HUMAN|HGNC=5889|UniProtKB=A0A075B6J9 A0A075B6J9 IGLV2-18 PTHR23267:SF444 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 2-18-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=1118|UniProtKB=Q10588 Q10588 BST1 PTHR10912:SF4 ADP-RIBOSYL CYCLASE ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 lymphocyte activation#GO:0046649;regulation of cell population proliferation#GO:0042127;positive regulation of cell population proliferation#GO:0008284;positive regulation of immune system process#GO:0002684;B cell proliferation#GO:0042100;lymphocyte proliferation#GO:0046651;cell population proliferation#GO:0008283;cellular process#GO:0009987;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;leukocyte proliferation#GO:0070661;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;regulation of immune system process#GO:0002682;regulation of leukocyte proliferation#GO:0070663;B cell activation#GO:0042113;positive regulation of cell activation#GO:0050867;positive regulation of biological process#GO:0048518;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;regulation of B cell proliferation#GO:0030888;mononuclear cell proliferation#GO:0032943 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 cyclase#PC00079 HUMAN|HGNC=31677|UniProtKB=Q6IWH7 Q6IWH7 ANO7 PTHR12308:SF22 NGEP-RELATED ANOCTAMIN-7 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;channel activity#GO:0015267;transporter activity#GO:0005215 macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;endomembrane system organization#GO:0010256;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;lipid transport#GO:0006869;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;lipid translocation#GO:0034204;lipid localization#GO:0010876;inorganic anion transport#GO:0015698;phospholipid translocation#GO:0045332;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;plasma membrane phospholipid scrambling#GO:0017121;chloride transport#GO:0006821;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;phospholipid transport#GO:0015914;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=4245|UniProtKB=O60609 O60609 GFRA3 PTHR10269:SF15 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=18991|UniProtKB=Q8IZF7 Q8IZF7 ADGRF2 PTHR45813:SF6 FAMILY NOT NAMED ADHESION G-PROTEIN COUPLED RECEPTOR F2 HUMAN|HGNC=18756|UniProtKB=Q9BYZ6 Q9BYZ6 RHOBTB2 PTHR24072:SF137 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;membrane organization#GO:0061024;transport#GO:0006810;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;vesicle organization#GO:0016050;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;phagocytosis#GO:0006909;regulation of organelle organization#GO:0033043;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036;apoptotic cell clearance#GO:0043277 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=5830|UniProtKB=A0A0C4DH90 A0A0C4DH90 IGKV3OR2-268 PTHR23267:SF331 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=28982|UniProtKB=Q12766 Q12766 HMGXB3 PTHR17609:SF2 HMG DOMAIN-CONTAINING PROTEIN 3 HMG DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=4166|UniProtKB=O95995 O95995 GAS8 PTHR31543:SF0 DYNEIN REGULATORY COMPLEX SUBUNIT 4 DYNEIN REGULATORY COMPLEX SUBUNIT 4 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;cellular process#GO:0009987;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization#GO:0008104 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=29267|UniProtKB=Q5MIZ7 Q5MIZ7 PPP4R3B PTHR23318:SF18 ATP SYNTHASE GAMMA-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3B ATP synthase#PC00002 HUMAN|HGNC=569|UniProtKB=Q9Y2T2 Q9Y2T2 AP3M1 PTHR10529:SF342 AP COMPLEX SUBUNIT MU AP-3 COMPLEX SUBUNIT MU-1 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 HUMAN|HGNC=19256|UniProtKB=Q8TCT0 Q8TCT0 CERK PTHR12358:SF25 SPHINGOSINE KINASE CERAMIDE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 kinase#PC00137 HUMAN|HGNC=22228|UniProtKB=A5PL33 A5PL33 KRBA1 PTHR22740:SF3 PROTEIN KRBA1 PROTEIN KRBA1 HUMAN|HGNC=10457|UniProtKB=O15537 O15537 RS1 PTHR24543:SF295 MULTICOPPER OXIDASE-RELATED RETINOSCHISIN oxidoreductase#PC00176 HUMAN|HGNC=7421|UniProtKB=P00403 P00403 MT-CO2 PTHR22888:SF9 CYTOCHROME C OXIDASE, SUBUNIT II CYTOCHROME C OXIDASE SUBUNIT 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;inorganic cation transmembrane transporter activity#GO:0022890 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 oxidoreductase#PC00176 Gonadotropin-releasing hormone receptor pathway#P06664>COX2#P06734;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06686;Gonadotropin-releasing hormone receptor pathway#P06664>COX2#G06899 HUMAN|HGNC=3494|UniProtKB=P41161 P41161 ETV5 PTHR11849:SF160 ETS ETS TRANSLOCATION VARIANT 5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=11277|UniProtKB=O15269 O15269 SPTLC1 PTHR13693:SF2 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 1 transaminase#PC00216 Biotin biosynthesis#P02731>8-Amino-7-oxononanoate synthase#P02858 HUMAN|HGNC=32525|UniProtKB=A6NHY2 A6NHY2 ANKDD1B PTHR24125:SF1 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1B HUMAN|HGNC=20858|UniProtKB=Q15043 Q15043 SLC39A14 PTHR12191:SF5 SOLUTE CARRIER FAMILY 39 METAL CATION SYMPORTER ZIP14 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=11311|UniProtKB=Q05066 Q05066 SRY PTHR10270:SF199 SOX TRANSCRIPTION FACTOR SEX-DETERMINING REGION Y PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;reproductive process#GO:0022414;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;developmental process involved in reproduction#GO:0003006;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=25308|UniProtKB=Q9H0C3 Q9H0C3 TMEM117 PTHR31226:SF1 TRANSMEMBRANE PROTEIN 117 TRANSMEMBRANE PROTEIN 117 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;signaling#GO:0023052 HUMAN|HGNC=7798|UniProtKB=Q15653 Q15653 NFKBIB PTHR47303:SF1 FAMILY NOT NAMED NF-KAPPA-B INHIBITOR BETA HUMAN|HGNC=13625|UniProtKB=Q9BXT2 Q9BXT2 CACNG6 PTHR15025:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-6 SUBUNIT calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;channel activity#GO:0015267;transporter activity#GO:0005215 regulation of transmembrane transport#GO:0034762;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;calcium ion transmembrane transport#GO:0070588;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;localization#GO:0051179;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;divalent inorganic cation transport#GO:0072511;regulation of ion transport#GO:0043269 membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;sarcolemma#GO:0042383;voltage-gated calcium channel complex#GO:0005891;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=26953|UniProtKB=Q2LD37 Q2LD37 KIAA1109 PTHR31640:SF1 TRANSMEMBRANE PROTEIN KIAA1109 TRANSMEMBRANE PROTEIN KIAA1109 HUMAN|HGNC=11998|UniProtKB=P04637 P04637 TP53 PTHR11447:SF6 CELLULAR TUMOR ANTIGEN P53 CELLULAR TUMOR ANTIGEN P53 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 P53-like transcription factor#PC00253 p53 pathway feedback loops 2#P04398>p53#P04668;p53 pathway by glucose deprivation#P04397>p53#P04640;p53 pathway#P00059>p53#P01485;Apoptosis signaling pathway#P00006>p53#P00273;P53 pathway feedback loops 1#P04392>p53#P04539;Huntington disease#P00029>p53#P00797;p53 pathway#P00059>p53#G04702;Wnt signaling pathway#P00057>p53#P01430 HUMAN|HGNC=35406|UniProtKB=P0CB48 P0CB48 UBTFL6 PTHR46318:SF1 UPSTREAM BINDING TRANSCRIPTION FACTOR UPSTREAM-BINDING FACTOR 1-LIKE PROTEIN 1-RELATED DNA-binding transcription factor#PC00218 HUMAN|HGNC=41907|UniProtKB=Q6NZ63 Q6NZ63 STEAP1B PTHR14239:SF3 DUDULIN-RELATED METALLOREDUCTASE STEAP1-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;iron ion transmembrane transport#GO:0034755;localization#GO:0051179;establishment of localization#GO:0051234;oxidation-reduction process#GO:0055114;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;metabolic process#GO:0008152 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=4925|UniProtKB=P52790 P52790 HK3 PTHR19443:SF1 HEXOKINASE HEXOKINASE-3 transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;cellular homeostasis#GO:0019725;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;chemical homeostasis#GO:0048878;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;cellular chemical homeostasis#GO:0055082;glycolytic process#GO:0006096;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 HUMAN|HGNC=12157|UniProtKB=A0A5B9 A0A5B9 TRBC2 PTHR23266:SF340 IMMUNOGLOBULIN HEAVY CHAIN T CELL RECEPTOR BETA CHAIN MC.7.G5-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 T cell activation#P00053>TCR Beta#P01299 HUMAN|HGNC=8664|UniProtKB=Q9Y5I2 Q9Y5I2 PCDHA10 PTHR24028:SF124 CADHERIN-87A PROTOCADHERIN ALPHA-10 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=4942|UniProtKB=P01909 P01909 HLA-DQA1 PTHR19944:SF59 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ ALPHA 1 CHAIN major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 HUMAN|HGNC=11946|UniProtKB=P48788 P48788 TNNI2 PTHR13738:SF15 TROPONIN I TROPONIN I, FAST SKELETAL MUSCLE multicellular organismal process#GO:0032501;muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008 supramolecular complex#GO:0099080;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 non-motor actin binding protein#PC00165 HUMAN|HGNC=29009|UniProtKB=Q6AHZ1 Q6AHZ1 ZNF518A PTHR24392:SF39 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 518A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=18348|UniProtKB=Q8IUC6 Q8IUC6 TICAM1 PTHR47230:SF1 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 positive regulation of gene expression#GO:0010628;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of cytokine production involved in immune response#GO:0002718;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of lymphocyte activation#GO:0051251;production of molecular mediator of immune response#GO:0002440;regulation of biological process#GO:0050789;defense response#GO:0006952;leukocyte activation#GO:0045321;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;regulation of immune response#GO:0050776;cellular response to biotic stimulus#GO:0071216;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of inflammatory response#GO:0050729;positive regulation of macromolecule metabolic process#GO:0010604;response to lipopolysaccharide#GO:0032496;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of defense response#GO:0031347;multicellular organismal process#GO:0032501;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;cellular response to lipopolysaccharide#GO:0071222;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;response to lipid#GO:0033993;biosynthetic process#GO:0009058;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;cytokine production#GO:0001816;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;response to bacterium#GO:0009617;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;immune effector process#GO:0002252;signaling#GO:0023052;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of inflammatory response#GO:0050727;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;regulation of nucleic acid-templated transcription#GO:1903506;response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;positive regulation of leukocyte activation#GO:0002696;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of cytokine production#GO:0001819;positive regulation of immune effector process#GO:0002699;response to molecule of bacterial origin#GO:0002237;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;positive regulation of response to external stimulus#GO:0032103;RNA biosynthetic process#GO:0032774;toll-like receptor signaling pathway#GO:0002224;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of production of molecular mediator of immune response#GO:0002700;aromatic compound biosynthetic process#GO:0019438;positive regulation of cell activation#GO:0050867;positive regulation of defense response#GO:0031349;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;response to organic cyclic compound#GO:0014070;pattern recognition receptor signaling pathway#GO:0002221;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;cellular response to oxygen-containing compound#GO:1901701;positive regulation of metabolic process#GO:0009893;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of lymphocyte activation#GO:0051249;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;cellular macromolecule biosynthetic process#GO:0034645;regulation of response to external stimulus#GO:0032101;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;lymphocyte activation#GO:0046649;leukocyte mediated immunity#GO:0002443;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;nucleic acid metabolic process#GO:0090304;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of cellular macromolecule biosynthetic process#GO:2000112 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TRIF#P01344 HUMAN|HGNC=8706|UniProtKB=Q9Y5G5 Q9Y5G5 PCDHGA8 PTHR24028:SF72 CADHERIN-87A PROTOCADHERIN GAMMA-A8 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=26624|UniProtKB=Q8NAX2 Q8NAX2 KDF1 PTHR35085:SF1 KERATINOCYTE DIFFERENTIATION FACTOR 1 KERATINOCYTE DIFFERENTIATION FACTOR 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell division#GO:0051301;cellular process#GO:0009987;regulation of cell division#GO:0051302;regulation of cellular process#GO:0050794 cell junction#GO:0030054;cellular anatomical entity#GO:0110165 HUMAN|HGNC=13829|UniProtKB=Q9GZT5 Q9GZT5 WNT10A PTHR12027:SF89 WNT RELATED PROTEIN WNT-10A receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=10331|UniProtKB=P47914 P47914 RPL29 PTHR12884:SF23 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=29346|UniProtKB=Q9C0I9 Q9C0I9 LRRC27 PTHR16083:SF3 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 27 HUMAN|HGNC=19685|UniProtKB=P49903 P49903 SEPHS1 PTHR10256:SF2 SELENIDE, WATER DIKINASE SELENIDE, WATER DIKINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transferase#PC00220 HUMAN|HGNC=25744|UniProtKB=Q9H9L7 Q9H9L7 AKIRIN1 PTHR13293:SF9 UNCHARACTERIZED AKIRIN-1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cellular component biogenesis#GO:0044087;innate immune response#GO:0045087;defense response#GO:0006952;regulation of cellular component movement#GO:0051270;positive regulation of innate immune response#GO:0045089;regulation of immune response#GO:0050776;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of defense response#GO:0031347;plasma membrane bounded cell projection assembly#GO:0120031;taxis#GO:0042330;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;regulation of locomotion#GO:0040012;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;growth#GO:0040007;biosynthetic process#GO:0009058;positive regulation of leukocyte migration#GO:0002687;muscle structure development#GO:0061061;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of chemotaxis#GO:0050920;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;myeloid leukocyte migration#GO:0097529;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cell motility#GO:0048870;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;tissue development#GO:0009888;cell chemotaxis#GO:0060326;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;positive regulation of cellular component organization#GO:0051130;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;positive regulation of response to biotic stimulus#GO:0002833;transcription by RNA polymerase II#GO:0006366;response to external biotic stimulus#GO:0043207;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;leukocyte migration#GO:0050900;granulocyte migration#GO:0097530;positive regulation of immune response#GO:0050778;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;macrophage chemotaxis#GO:0048246;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;RNA biosynthetic process#GO:0032774;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;aromatic compound biosynthetic process#GO:0019438;positive regulation of defense response#GO:0031349;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cell projection organization#GO:0031346;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of transcription, DNA-templated#GO:0006355;positive regulation of response to stimulus#GO:0048584;granulocyte chemotaxis#GO:0071621;positive regulation of metabolic process#GO:0009893;negative regulation of cell population proliferation#GO:0008285;positive regulation of cellular component biogenesis#GO:0044089;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;positive regulation of cell differentiation#GO:0045597;developmental growth#GO:0048589;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of RNA metabolic process#GO:0051252;positive regulation of developmental process#GO:0051094;cell projection assembly#GO:0030031;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;regulation of innate immune response#GO:0045088;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cell projection assembly#GO:0060491;biological regulation#GO:0065007;positive regulation of leukocyte chemotaxis#GO:0002690;cell migration#GO:0016477;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=17890|UniProtKB=O60760 O60760 HPGDS PTHR11571:SF224 GLUTATHIONE S-TRANSFERASE HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=8707|UniProtKB=Q9Y5G4 Q9Y5G4 PCDHGA9 PTHR24028:SF86 CADHERIN-87A PROTOCADHERIN GAMMA-A9 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 HUMAN|HGNC=21863|UniProtKB=Q9NW13 Q9NW13 RBM28 PTHR48039:SF2 RNA-BINDING MOTIF PROTEIN 14B RNA-BINDING PROTEIN 28 HUMAN|HGNC=7139|UniProtKB=P98177 P98177 FOXO4 PTHR45767:SF3 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 PI3 kinase pathway#P00048>FOXO#P01198 HUMAN|HGNC=3684|UniProtKB=P10767 P10767 FGF6 PTHR11486:SF25 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 6 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=25144|UniProtKB=Q8N398 Q8N398 VWA5B2 PTHR46299:SF2 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2-RELATED VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2 HUMAN|HGNC=12524|UniProtKB=Q16739 Q16739 UGCG PTHR12726:SF0 CERAMIDE GLUCOSYLTRANSFERASE CERAMIDE GLUCOSYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity, transferring glycosyl groups#GO:0016757;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 glycosyltransferase#PC00111 HUMAN|HGNC=9636|UniProtKB=O75365 O75365 PTP4A3 PTHR23339:SF98 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN TYROSINE PHOSPHATASE TYPE IVA 3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 HUMAN|HGNC=10921|UniProtKB=Q16348 Q16348 SLC15A2 PTHR11654:SF595 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 2 transporter#PC00227 HUMAN|HGNC=463|UniProtKB=Q9UKV5 Q9UKV5 AMFR PTHR15067:SF5 E3 UBIQUITIN-PROTEIN LIGASE RNF8 E3 UBIQUITIN-PROTEIN LIGASE AMFR ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=31299|UniProtKB=A6NIJ9 A6NIJ9 OR6C70 PTHR26454:SF17 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C70 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=26918|UniProtKB=Q0VAQ4 Q0VAQ4 SMAGP PTHR47394:SF1 SMALL CELL ADHESION GLYCOPROTEIN SMALL CELL ADHESION GLYCOPROTEIN HUMAN|HGNC=19708|UniProtKB=Q86WU2 Q86WU2 LDHD PTHR11748:SF111 D-LACTATE DEHYDROGENASE D-LACTATE DEHYDROGENASE, MITOCHONDRIAL-RELATED nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 dehydrogenase#PC00092 HUMAN|HGNC=25107|UniProtKB=Q6IPT2 Q6IPT2 FAM71E1 PTHR22574:SF5 UNCHARACTERIZED PROTEIN FAM71E1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=13636|UniProtKB=Q9HBA9 Q9HBA9 FOLH1B PTHR10404:SF36 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153 HUMAN|HGNC=11206|UniProtKB=P23497 P23497 SP100 PTHR46386:SF1 NUCLEAR BODY PROTEIN SP140 NUCLEAR AUTOANTIGEN SP-100 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=14466|UniProtKB=Q9ULP0 Q9ULP0 NDRG4 PTHR11034:SF21 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG4 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;brain development#GO:0007420;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;central nervous system development#GO:0007417;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;head development#GO:0060322;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;ERK1 and ERK2 cascade#GO:0070371;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 serine protease#PC00203 HUMAN|HGNC=17042|UniProtKB=Q9UHX1 Q9UHX1 PUF60 PTHR47330:SF1 POLY(U)-BINDING-SPLICING FACTOR PUF60-B-RELATED POLY(U)-BINDING-SPLICING FACTOR PUF60 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974 RNA splicing factor#PC00148 HUMAN|HGNC=10274|UniProtKB=O75695 O75695 RP2 PTHR15440:SF0 XRP2 PROTEIN PROTEIN XRP2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 HUMAN|HGNC=19576|UniProtKB=A3KFT3 A3KFT3 OR2M5 PTHR26453:SF28 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2M5 transmembrane signal receptor#PC00197 HUMAN|HGNC=15588|UniProtKB=Q96C24 Q96C24 SYTL4 PTHR45716:SF4 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=14388|UniProtKB=Q9HCN6 Q9HCN6 GP6 PTHR11738:SF116 MHC CLASS I NK CELL RECEPTOR PLATELET GLYCOPROTEIN VI immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=10328|UniProtKB=P61353 P61353 RPL27 PTHR10497:SF11 60S RIBOSOMAL PROTEIN L27 60S RIBOSOMAL PROTEIN L27 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=9279|UniProtKB=Q9P0J1 Q9P0J1 PDP1 PTHR13832:SF627 PROTEIN PHOSPHATASE 2C [PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 1, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=9218|UniProtKB=Q01851 Q01851 POU4F1 PTHR11636:SF42 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|Ensembl=ENSG00000266286|UniProtKB=A0A140TA64 A0A140TA64 LOC100996750 PTHR23262:SF223 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-6-RELATED HUMAN|HGNC=29289|UniProtKB=Q9P260 Q9P260 RELCH PTHR32059:SF0 RAB11-BINDING PROTEIN RELCH RAB11-BINDING PROTEIN RELCH HUMAN|HGNC=9490|UniProtKB=P98073 P98073 TMPRSS15 PTHR24253:SF71 TRANSMEMBRANE PROTEASE SERINE ENTEROPEPTIDASE serine protease#PC00203 HUMAN|HGNC=18795|UniProtKB=O15205 O15205 UBD PTHR47731:SF1 UBIQUITIN D UBIQUITIN D proteasome binding#GO:0070628;protein-containing complex binding#GO:0044877;binding#GO:0005488 response to external biotic stimulus#GO:0043207;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;protein catabolic process#GO:0030163;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;innate immune response#GO:0045087;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;programmed cell death#GO:0012501;cellular nitrogen compound metabolic process#GO:0034641;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of response to stimulus#GO:0048584;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;positive regulation of programmed cell death#GO:0043068;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;cell death#GO:0008219;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;cellular catabolic process#GO:0044248;positive regulation of apoptotic process#GO:0043065;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;positive regulation of cell death#GO:0010942;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4047|UniProtKB=O00144 O00144 FZD9 PTHR11309:SF79 FRIZZLED FRIZZLED-9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>FRP#P00237;Wnt signaling pathway#P00057>Frizzled#P01428;Wnt signaling pathway#P00057>sFRP#P01434;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 HUMAN|HGNC=21498|UniProtKB=Q676U5 Q676U5 ATG16L1 PTHR19878:SF6 AUTOPHAGY PROTEIN 16-LIKE AUTOPHAGY-RELATED PROTEIN 16-1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;autophagosome organization#GO:1905037;protein metabolic process#GO:0019538;autophagy#GO:0006914;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;whole membrane#GO:0098805 HUMAN|HGNC=16920|UniProtKB=Q99828 Q99828 CIB1 PTHR45791:SF3 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING PROTEIN 1 HUMAN|HGNC=4015|UniProtKB=P22083 P22083 FUT4 PTHR11929:SF132 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE 4 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111 HUMAN|HGNC=10703|UniProtKB=O95486 O95486 SEC24A PTHR13803:SF1 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24A cation binding#GO:0043169;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;Golgi vesicle budding#GO:0048194;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=32933|UniProtKB=Q6IPU0 Q6IPU0 CENPP PTHR28577:SF1 CENTROMERE PROTEIN P CENTROMERE PROTEIN P membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=10336|UniProtKB=P62910 P62910 RPL32 PTHR23413:SF6 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N 60S RIBOSOMAL PROTEIN L32 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=20882|UniProtKB=Q9NWT1 Q9NWT1 PAK1IP1 PTHR42968:SF32 WD REPEAT-CONTAINING P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=2191|UniProtKB=Q05707 Q05707 COL14A1 PTHR24020:SF15 COLLAGEN ALPHA COLLAGEN ALPHA-1(XIV) CHAIN extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=29002|UniProtKB=O14526 O14526 FCHO1 PTHR23065:SF6 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 F-BAR DOMAIN ONLY PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;protein-containing complex subunit organization#GO:0043933 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=9824|UniProtKB=P43351 P43351 RAD52 PTHR12132:SF1 DNA REPAIR AND RECOMBINATION PROTEIN RAD52, RAD59 DNA REPAIR PROTEIN RAD52 HOMOLOG DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 HUMAN|HGNC=29955|UniProtKB=Q86UW1 Q86UW1 SLC51A PTHR23423:SF11 ORGANIC SOLUTE TRANSPORTER-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT ALPHA localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=19167|UniProtKB=Q9P2E2 Q9P2E2 KIF17 PTHR24115:SF355 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF17 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=12429|UniProtKB=Q9GZX9 Q9GZX9 TWSG1 PTHR12312:SF16 TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED TWISTED GASTRULATION PROTEIN HOMOLOG 1 response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;BMP signaling pathway#GO:0030509;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;response to stimulus#GO:0050896;cellular response to BMP stimulus#GO:0071773;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 DPP signaling pathway#P06213>TSG#P06287;BMP/activin signaling pathway-drosophila#P06211>TSG#P06242;SCW signaling pathway#P06216>TSG#P06330;DPP-SCW signaling pathway#P06212>TSG#P06258 HUMAN|HGNC=2891|UniProtKB=O94907 O94907 DKK1 PTHR12113:SF11 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=16677|UniProtKB=Q92688 Q92688 ANP32B PTHR11375:SF2 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER B protein binding#GO:0005515;binding#GO:0005488;histone binding#GO:0042393 regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=25282|UniProtKB=Q96TA1 Q96TA1 NIBAN2 PTHR14392:SF2 NIBAN FAMILY MEMBER PROTEIN NIBAN 2 HUMAN|HGNC=17055|UniProtKB=Q9HAP2 Q9HAP2 MLXIP PTHR15741:SF23 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MLX-INTERACTING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=11119|UniProtKB=Q99835 Q99835 SMO PTHR11309:SF35 FRIZZLED SMOOTHENED HOMOLOG signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;signaling receptor binding#GO:0005102;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;smoothened signaling pathway#GO:0007224;positive regulation of signal transduction#GO:0009967;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;central nervous system development#GO:0007417;axonogenesis#GO:0007409;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;cellular component organization#GO:0016043;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;taxis#GO:0042330;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of signaling#GO:0023051;non-canonical Wnt signaling pathway#GO:0035567;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of response to stimulus#GO:0048584;axon guidance#GO:0007411;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;Wnt signaling pathway#GO:0016055;chemotaxis#GO:0006935;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Hedgehog signaling pathway#P00025>Smoothened#P00685 HUMAN|HGNC=6541|UniProtKB=P07195 P07195 LDHB PTHR43128:SF29 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE B CHAIN oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092 HUMAN|HGNC=26616|UniProtKB=Q8NB37 Q8NB37 GATD1 PTHR48094:SF18 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=24713|UniProtKB=Q2TAL8 Q2TAL8 QRICH1 PTHR45736:SF8 ZINC FINGER MYM-TYPE PROTEIN GLUTAMINE-RICH PROTEIN 1 zinc finger transcription factor#PC00244 HUMAN|HGNC=29001|UniProtKB=O14524 O14524 NEMP1 PTHR13598:SF2 UNCHARACTERIZED NUCLEAR ENVELOPE INTEGRAL MEMBRANE PROTEIN 1 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=23455|UniProtKB=Q5VYY2 Q5VYY2 LIPM PTHR11005:SF12 LYSOSOMAL ACID LIPASE-RELATED LIPASE MEMBER M lipase#PC00143 HUMAN|HGNC=9441|UniProtKB=P51817 P51817 PRKX PTHR24353:SF133 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Enkephalin release#P05913>PKA#P05972;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 HUMAN|HGNC=23514|UniProtKB=Q8N7W2 Q8N7W2 BEND7 PTHR35068:SF1 BEN DOMAIN-CONTAINING PROTEIN 7 BEN DOMAIN-CONTAINING PROTEIN 7 HUMAN|HGNC=26328|UniProtKB=A6NJ46 A6NJ46 NKX6-3 PTHR24340:SF20 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-6.3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=20134|UniProtKB=Q86SX6 Q86SX6 GLRX5 PTHR10293:SF16 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-3-RELATED reductase#PC00198 HUMAN|HGNC=23116|UniProtKB=Q9HC62 Q9HC62 SENP2 PTHR12606:SF11 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 2 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein-specific protease activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 protease#PC00190 HUMAN|Gene=YE027_HUMAN|UniProtKB=Q8NA96 Q8NA96 - PTHR21859:SF42 ACROSOME-SPECIFIC PROTEIN SUBFAMILY NOT NAMED HUMAN|HGNC=23657|UniProtKB=Q9Y223 Q9Y223 GNE PTHR18964:SF149 ROK (REPRESSOR, ORF, KINASE) FAMILY BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE DNA-binding transcription factor#PC00218 HUMAN|HGNC=34385|UniProtKB=B2RC85 B2RC85 RSPH10B2 PTHR46613:SF1 RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED HUMAN|HGNC=23513|UniProtKB=Q70EL1 Q70EL1 USP54 PTHR22975:SF5 UBIQUITIN SPECIFIC PROTEINASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 54 cysteine protease#PC00081 HUMAN|HGNC=13601|UniProtKB=Q9UKA2 Q9UKA2 FBXL4 PTHR13318:SF152 UNCHARACTERIZED F-BOX/LRR-REPEAT PROTEIN 4 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=17812|UniProtKB=Q9Y2J4 Q9Y2J4 AMOTL2 PTHR14826:SF3 ANGIOMOTIN ANGIOMOTIN-LIKE PROTEIN 2 establishment or maintenance of cell polarity#GO:0007163;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;developmental process#GO:0032502;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;system development#GO:0048731;establishment of cell polarity#GO:0030010;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of cellular component movement#GO:0051270;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;regulation of cell motility#GO:2000145;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;tube development#GO:0035295;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;hippo signaling#GO:0035329;angiogenesis#GO:0001525;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 intracellular vesicle#GO:0097708;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;apical junction complex#GO:0043296;plasma membrane#GO:0005886 HUMAN|HGNC=2269|UniProtKB=P10606 P10606 COX5B PTHR10122:SF0 CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular localization#GO:0051641;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;mitochondrial transmembrane transport#GO:1990542;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;intracellular transport#GO:0046907;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;aerobic electron transport chain#GO:0019646;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial transport#GO:0006839;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;establishment of localization in cell#GO:0051649;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 oxidase#PC00175 HUMAN|HGNC=9348|UniProtKB=Q9UKN5 Q9UKN5 PRDM4 PTHR16515:SF2 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 4 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=2291|UniProtKB=P24311 P24311 COX7B PTHR16716:SF0 CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 7B, MITOCHONDRIAL oxidase#PC00175 HUMAN|HGNC=14943|UniProtKB=Q9H7J1 Q9H7J1 PPP1R3E PTHR12307:SF20 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3E phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase 1 binding#GO:0008157;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 monosaccharide metabolic process#GO:0005996;glucan metabolic process#GO:0044042;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;energy derivation by oxidation of organic compounds#GO:0015980;regulation of biological process#GO:0050789;cellular glucan metabolic process#GO:0006073;glucan biosynthetic process#GO:0009250;regulation of biosynthetic process#GO:0009889;oxidation-reduction process#GO:0055114;regulation of macromolecule biosynthetic process#GO:0010556;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;glycogen biosynthetic process#GO:0005978;regulation of glucose metabolic process#GO:0010906;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;polysaccharide metabolic process#GO:0005976;regulation of cellular biosynthetic process#GO:0031326;cellular carbohydrate metabolic process#GO:0044262;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;hexose metabolic process#GO:0019318;energy reserve metabolic process#GO:0006112;cellular polysaccharide biosynthetic process#GO:0033692;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular polysaccharide metabolic process#GO:0044264;small molecule metabolic process#GO:0044281 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 phosphatase modulator#PC00184 HUMAN|HGNC=21716|UniProtKB=Q7Z443 Q7Z443 PKD1L3 PTHR10877:SF136 POLYCYSTIN FAMILY MEMBER POLYCYSTIC KIDNEY DISEASE PROTEIN 1-LIKE 3 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133 HUMAN|HGNC=29307|UniProtKB=Q9P1Y5 Q9P1Y5 CAMSAP3 PTHR21595:SF2 UNCHARACTERIZED CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;negative regulation of biological process#GO:0048519;protein-containing complex disassembly#GO:0032984;cellular protein complex disassembly#GO:0043624;regulation of organelle organization#GO:0033043;microtubule depolymerization#GO:0007019;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 HUMAN|HGNC=16011|UniProtKB=Q9Y576 Q9Y576 ASB1 PTHR24173:SF27 FAMILY NOT NAMED ANKYRIN REPEAT AND SOCS BOX PROTEIN 1 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=8855|UniProtKB=Q92968 Q92968 PEX13 PTHR19332:SF1 PEROXISOMAL MEMBRANE PROTEIN PEX13 PEROXISOMAL MEMBRANE PROTEIN PEX13 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein targeting to peroxisome#GO:0006625;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein localization to peroxisome#GO:0072662;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;microbody membrane#GO:0031903;protein-containing complex#GO:0032991;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777 primary active transporter#PC00068 HUMAN|HGNC=30289|UniProtKB=Q9NYN1 Q9NYN1 RASL12 PTHR24070:SF252 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE PROTEIN FAMILY MEMBER 12 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=21481|UniProtKB=Q9BYZ2 Q9BYZ2 LDHAL6B PTHR43128:SF8 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A-LIKE 6B oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092 HUMAN|HGNC=5299|UniProtKB=Q13639 Q13639 HTR4 PTHR24247:SF179 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 4 cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 5HT4 type receptor mediated signaling pathway#P04376>5HT4 Receptor#P04427;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=14819|UniProtKB=Q8NGE0 Q8NGE0 OR10AD1 PTHR26453:SF215 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10AD1 transmembrane signal receptor#PC00197 HUMAN|HGNC=1742|UniProtKB=P50851 P50851 LRBA PTHR13743:SF64 BEIGE/BEACH-RELATED LIPOPOLYSACCHARIDE-RESPONSIVE AND BEIGE-LIKE ANCHOR PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 localization#GO:0051179;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=10989|UniProtKB=Q00325 Q00325 SLC25A3 PTHR45671:SF10 SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED PHOSPHATE CARRIER PROTEIN, MITOCHONDRIAL secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;inorganic anion transport#GO:0015698;anion transmembrane transport#GO:0098656 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158 HUMAN|HGNC=32060|UniProtKB=Q5TEC6 Q5TEC6 H3-2 PTHR11426:SF247 HISTONE H3 HISTONE H3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 histone#PC00118 HUMAN|HGNC=4394|UniProtKB=P19087 P19087 GNAT2 PTHR10218:SF68 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-2 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;detection of chemical stimulus#GO:0009593;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 9+0 non-motile cilium#GO:0097731;membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;non-motile cilium#GO:0097730;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;cytoplasmic side of plasma membrane#GO:0009898;intraciliary transport particle#GO:0030990;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 HUMAN|HGNC=17057|UniProtKB=Q9Y2G2 Q9Y2G2 CARD8 PTHR46985:SF2 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 8 HUMAN|HGNC=31253|UniProtKB=Q8NH02 Q8NH02 OR2T29 PTHR26453:SF161 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T29-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=13199|UniProtKB=P98169 P98169 ZXDB PTHR46179:SF6 ZINC FINGER PROTEIN ZINC FINGER X-LINKED PROTEIN ZXDB transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|Ensembl=ENSG00000284891|UniProtKB=A0A4W9AIG4 A0A4W9AIG4 OR2A14 PTHR26453:SF27 OLFACTORY RECEPTOR OLFACTORY RECEPTOR-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=10727|UniProtKB=O15041 O15041 SEMA3E PTHR11036:SF22 SEMAPHORIN SEMAPHORIN-3E receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=30225|UniProtKB=Q9NWF4 Q9NWF4 SLC52A1 PTHR12929:SF20 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 1 anion transmembrane transporter activity#GO:0008509;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=26116|UniProtKB=Q8TBK2 Q8TBK2 SETD6 PTHR13271:SF34 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE N-LYSINE METHYLTRANSFERASE SETD6 N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein alkylation#GO:0008213;protein methylation#GO:0006479;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 methyltransferase#PC00155 HUMAN|HGNC=25965|UniProtKB=Q8IUZ0 Q8IUZ0 LRRC49 PTHR15454:SF23 NISCHARIN RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 49 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28968|UniProtKB=Q14153 Q14153 FAM53B PTHR28567:SF1 FAMILY NOT NAMED PROTEIN FAM53B cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;positive regulation of signal transduction#GO:0009967;transport#GO:0006810;regulation of signaling#GO:0023051;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;positive regulation of Wnt signaling pathway#GO:0030177;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;positive regulation of response to stimulus#GO:0048584;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;protein localization to organelle#GO:0033365;protein import#GO:0017038;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;nuclear transport#GO:0051169;Wnt signaling pathway#GO:0016055;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;establishment of protein localization to organelle#GO:0072594;cell communication#GO:0007154;peptide transport#GO:0015833;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;protein transport#GO:0015031;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28428|UniProtKB=Q9BUL5 Q9BUL5 PHF23 PTHR14571:SF8 UNCHARACTERIZED PHD FINGER PROTEIN 23 cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;proteolysis#GO:0006508;negative regulation of cellular component organization#GO:0051129;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein ubiquitination#GO:0016567;protein-containing complex disassembly#GO:0032984;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;regulation of macroautophagy#GO:0016241;negative regulation of autophagy#GO:0010507;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;regulation of autophagosome maturation#GO:1901096;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of autophagosome assembly#GO:2000785;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;negative regulation of organelle organization#GO:0010639;catabolic process#GO:0009056;autophagosome maturation#GO:0097352;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;negative regulation of macroautophagy#GO:0016242;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;organelle assembly#GO:0070925;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 HUMAN|HGNC=50|UniProtKB=Q9NP78 Q9NP78 ABCB9 PTHR24221:SF242 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 9 binding#GO:0005488;catalytic activity#GO:0003824;MHC protein binding#GO:0042287;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;signaling receptor binding#GO:0005102;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;hydrolase activity#GO:0016787;amide transmembrane transporter activity#GO:0042887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;peptide transmembrane transporter activity#GO:1904680;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 localization#GO:0051179;antigen processing and presentation#GO:0019882;immune system process#GO:0002376;transmembrane transport#GO:0055085;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=16225|UniProtKB=Q5VYV7 Q5VYV7 SLX4IP PTHR28557:SF1 PROTEIN SLX4IP PROTEIN SLX4IP HUMAN|HGNC=8176|UniProtKB=Q9GZK7 Q9GZK7 OR11A1 PTHR24242:SF178 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11A1 G-protein coupled receptor#PC00021 HUMAN|HGNC=28187|UniProtKB=Q8WUU8 Q8WUU8 TMEM174 PTHR31020:SF1 TRANSMEMBRANE PROTEIN 174 TRANSMEMBRANE PROTEIN 174 HUMAN|HGNC=32697|UniProtKB=Q1XH10 Q1XH10 SKIDA1 PTHR23187:SF2 FLJ44216 PROTEIN-RELATED SKI/DACH DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=25718|UniProtKB=Q8NF37 Q8NF37 LPCAT1 PTHR23063:SF1 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE 1 acyltransferase#PC00042 HUMAN|HGNC=30298|UniProtKB=Q96RL1 Q96RL1 UIMC1 PTHR15932:SF2 UBIQUITIN INTERACTION MOTIF-CONTAINING PROTEIN 1 BRCA1-A COMPLEX SUBUNIT RAP80 protein binding#GO:0005515;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;histone binding#GO:0042393;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 DNA repair#GO:0006281;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;protein K63-linked deubiquitination#GO:0070536;positive regulation of cellular metabolic process#GO:0031325;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;chromatin organization#GO:0006325;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of DNA repair#GO:0045739;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of DNA repair#GO:0006282;positive regulation of response to stimulus#GO:0048584;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;histone deubiquitination#GO:0016578;protein metabolic process#GO:0019538;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=31816|UniProtKB=P0C7M6 P0C7M6 IQCF3 PTHR21633:SF5 IQ MOTIF CONTAINING F IQ DOMAIN-CONTAINING PROTEIN F3 protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 HUMAN|HGNC=26356|UniProtKB=Q96LI9 Q96LI9 CXorf58 PTHR33504:SF1 NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4 CHROMOSOME X OPEN READING FRAME 58 dehydrogenase#PC00092 HUMAN|HGNC=20423|UniProtKB=Q9P0W8 Q9P0W8 SPATA7 PTHR14917:SF2 SPERMATOGENESIS-ASSOCIATED PROTEIN 7 SPERMATOGENESIS-ASSOCIATED PROTEIN 7 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;microtubule cytoskeleton organization#GO:0000226;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;multicellular organismal homeostasis#GO:0048871;tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;protein localization to cilium#GO:0061512;microtubule-based process#GO:0007017;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;protein localization to organelle#GO:0033365;anatomical structure homeostasis#GO:0060249 9+0 non-motile cilium#GO:0097731;supramolecular complex#GO:0099080;axoneme#GO:0005930;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;photoreceptor outer segment#GO:0001750;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;non-motile cilium#GO:0097730;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;ciliary transition zone#GO:0035869;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;neuron projection#GO:0043005;ciliary basal body#GO:0036064;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=8828|UniProtKB=Q9HAT8 Q9HAT8 PELI2 PTHR12098:SF5 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 2 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 HUMAN|Ensembl=ENSG00000211974|UniProtKB=A0A0C4DH43 A0A0C4DH43 IGHV2-70D PTHR23266:SF330 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-70-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=9017|UniProtKB=P61925 P61925 PKIA PTHR15416:SF2 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;protein phosphorylation#GO:0006468;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;negative regulation of phosphorylation#GO:0042326;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase inhibitor#PC00139 HUMAN|HGNC=49|UniProtKB=Q9NUT2 Q9NUT2 ABCB8 PTHR24221:SF553 ATP-BINDING CASSETTE SUB-FAMILY B MITOCHONDRIAL POTASSIUM CHANNEL ATP-BINDING SUBUNIT pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=1943|UniProtKB=P15882 P15882 CHN1 PTHR46075:SF1 CHIMERIN FAMILY MEMBER N-CHIMAERIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009 HUMAN|HGNC=18828|UniProtKB=Q9Y375 Q9Y375 NDUFAF1 PTHR13194:SF23 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular component biogenesis#GO:0044085;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;protein-containing complex subunit organization#GO:0043933;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;mitochondrial respiratory chain complex assembly#GO:0033108;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;metabolic process#GO:0008152;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;organelle organization#GO:0006996;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25240|UniProtKB=Q4KMQ2 Q4KMQ2 ANO6 PTHR12308:SF21 NGEP-RELATED ANOCTAMIN-6 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;channel activity#GO:0015267;transporter activity#GO:0005215 macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;endomembrane system organization#GO:0010256;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;lipid transport#GO:0006869;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;lipid translocation#GO:0034204;lipid localization#GO:0010876;inorganic anion transport#GO:0015698;phospholipid translocation#GO:0045332;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;plasma membrane phospholipid scrambling#GO:0017121;chloride transport#GO:0006821;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;phospholipid transport#GO:0015914;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=2287|UniProtKB=P24310 P24310 COX7A1 PTHR10510:SF5 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular component biogenesis#GO:0044085;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;protein-containing complex subunit organization#GO:0043933;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;regulation of phosphorylation#GO:0042325;nucleoside phosphate biosynthetic process#GO:1901293;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;regulation of phosphate metabolic process#GO:0019220;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;organelle organization#GO:0006996;oxidative phosphorylation#GO:0006119;biological regulation#GO:0065007;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227 oxidase#PC00175 HUMAN|HGNC=23450|UniProtKB=A1L443 A1L443 NUTM2F PTHR22879:SF2 NUT FAMILY MEMBER 1 NUT FAMILY MEMBER 2F-RELATED HUMAN|HGNC=11823|UniProtKB=Q99727 Q99727 TIMP4 PTHR11844:SF26 METALLOPROTEASE INHIBITOR METALLOPROTEINASE INHIBITOR 4 metalloendopeptidase activity#GO:0004222;peptidase inhibitor activity#GO:0030414;metallopeptidase activity#GO:0008237;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of catabolic process#GO:0009895;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=44205|UniProtKB=P0DKB6 P0DKB6 MPC1L PTHR14154:SF9 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 1-LIKE PROTEIN HUMAN|HGNC=20270|UniProtKB=Q9NWQ9 Q9NWQ9 C14orf119 PTHR16260:SF4 SIMILAR TO 1700123O20RIK PROTEIN SUBFAMILY NOT NAMED HUMAN|HGNC=23794|UniProtKB=Q86VP3 Q86VP3 PACS2 PTHR13280:SF15 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 2 ion channel binding#GO:0044325;protein binding#GO:0005515;binding#GO:0005488 protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 HUMAN|HGNC=28261|UniProtKB=Q8TEA7 Q8TEA7 TBCK PTHR22957:SF168 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=16735|UniProtKB=A5PLL7 A5PLL7 TMEM189 PTHR48177:SF1 TRANSMEMBRANE PROTEIN 189 PLASMANYLETHANOLAMINE DESATURASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 Ubiquitin proteasome pathway#P00060>E2#P01491;Toll receptor signaling pathway#P00054>Uev1A#P01376 HUMAN|HGNC=14079|UniProtKB=Q9UGM1 Q9UGM1 CHRNA9 PTHR18945:SF489 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=34489|UniProtKB=A8K5M9 A8K5M9 C15orf62 PTHR15344:SF8 CDC42 EFFECTOR PROTEIN BORG HYPOTHETICAL PROTEIN LOC691418 HUMAN|HGNC=7156|UniProtKB=P09238 P09238 MMP10 PTHR10201:SF270 MATRIX METALLOPROTEINASE STROMELYSIN-2 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 HUMAN|HGNC=655|UniProtKB=P18085 P18085 ARF4 PTHR11711:SF110 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 4 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 HUMAN|HGNC=28771|UniProtKB=Q9BVC6 Q9BVC6 TMEM109 PTHR14550:SF2 TRANSMEMBRANE PROTEIN 109 TRANSMEMBRANE PROTEIN 109 response to ionizing radiation#GO:0010212;signal transduction#GO:0007165;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;signal transduction by p53 class mediator#GO:0072331;regulation of biological process#GO:0050789;cellular response to abiotic stimulus#GO:0071214;negative regulation of cell death#GO:0060548;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;response to stress#GO:0006950;response to radiation#GO:0009314;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332 HUMAN|HGNC=14573|UniProtKB=Q9Y227 Q9Y227 ENTPD4 PTHR11782:SF29 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 4 nucleotide phosphatase#PC00173 HUMAN|HGNC=20450|UniProtKB=Q3C1V8 Q3C1V8 BSX PTHR24327:SF35 HOMEOBOX PROTEIN BRAIN-SPECIFIC HOMEOBOX PROTEIN HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=16974|UniProtKB=Q6ZRS2 Q6ZRS2 SRCAP PTHR45685:SF1 HELICASE SRCAP-RELATED HELICASE SRCAP pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;histone binding#GO:0042393;ATPase activity#GO:0016887 negative regulation of gene expression#GO:0010629;protein-DNA complex subunit organization#GO:0071824;negative regulation of biological process#GO:0048519;histone exchange#GO:0043486;nucleosome organization#GO:0034728;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;gene silencing#GO:0016458;ATP-dependent chromatin remodeling#GO:0043044;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of gene expression#GO:0010468;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=44439|UniProtKB=C9JVI0 C9JVI0 USP17L11 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=29562|UniProtKB=Q9Y4F3 Q9Y4F3 MARF1 PTHR14379:SF3 LIMKAIN B LKAP MEIOSIS REGULATOR AND MRNA STABILITY FACTOR 1 RNA metabolism protein#PC00031 HUMAN|HGNC=32414|UniProtKB=P0DJD0 P0DJD0 RGPD1 PTHR23138:SF87 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17357|UniProtKB=Q9HC16 Q9HC16 APOBEC3G PTHR13857:SF20 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3G RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363 response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;RNA phosphodiester bond hydrolysis#GO:0090501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;defense response to virus#GO:0051607;demethylation#GO:0070988;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;transposition#GO:0032196;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;RNA-dependent DNA biosynthetic process#GO:0006278;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;nucleic acid phosphodiester bond hydrolysis#GO:0090305;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147 HUMAN|HGNC=34443|UniProtKB=A8MXK1 A8MXK1 VSTM5 PTHR12080:SF93 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 5 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=26053|UniProtKB=Q9NWX6 Q9NWX6 THG1L PTHR12729:SF6 UNCHARACTERIZED TRNA(HIS) GUANYLYLTRANSFERASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=30015|UniProtKB=Q96LB8 Q96LB8 PGLYRP4 PTHR11022:SF40 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN RECOGNITION PROTEIN 4 HUMAN|HGNC=24187|UniProtKB=Q9Y6J0 Q9Y6J0 CABIN1 PTHR15502:SF7 CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED CALCINEURIN-BINDING PROTEIN CABIN-1 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;organelle organization#GO:0006996;chromosome organization#GO:0051276;chromatin organization#GO:0006325;DNA replication-independent nucleosome organization#GO:0034724;protein-containing complex subunit organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 phosphatase inhibitor#PC00183 HUMAN|HGNC=29680|UniProtKB=Q8TBP6 Q8TBP6 SLC25A40 PTHR45760:SF5 FI19922P1-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 40 HUMAN|HGNC=773|UniProtKB=O14525 O14525 ASTN1 PTHR16592:SF8 FAMILY NOT NAMED ASTROTACTIN-1 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;developmental process#GO:0032502;localization of cell#GO:0051674;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;nervous system development#GO:0007399;localization#GO:0051179;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron migration#GO:0001764;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477;locomotion#GO:0040011 HUMAN|HGNC=30765|UniProtKB=Q9UKE5 Q9UKE5 TNIK PTHR48015:SF29 SERINE/THREONINE-PROTEIN KINASE TAO TRAF2 AND NCK-INTERACTING PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=4484|UniProtKB=P46089 P46089 GPR3 PTHR22750:SF39 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=726|UniProtKB=Q93070 Q93070 ART4 PTHR10339:SF1 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 4 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=6006|UniProtKB=Q9HBE5 Q9HBE5 IL21R PTHR23037:SF7 CYTOKINE RECEPTOR INTERLEUKIN-21 RECEPTOR transmembrane signal receptor#PC00197 HUMAN|HGNC=1836|UniProtKB=Q15744 Q15744 CEBPE PTHR23334:SF27 CCAAT/ENHANCER BINDING PROTEIN CCAAT/ENHANCER-BINDING PROTEIN EPSILON cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;myeloid cell differentiation#GO:0030099;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=5554|UniProtKB=P01743 P01743 IGHV1-46 PTHR23266:SF362 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-46 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=20978|UniProtKB=Q96RI8 Q96RI8 TAAR6 PTHR24249:SF271 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 6 G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=37473|UniProtKB=P0CW01 P0CW01 TSPY10 PTHR11875:SF12 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED PROTEIN 1-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=2453|UniProtKB=P49674 P49674 CSNK1E PTHR11909:SF440 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM EPSILON transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;transport#GO:0006810;positive regulation of proteasomal protein catabolic process#GO:1901800;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of protein catabolic process#GO:0042176;positive regulation of Wnt signaling pathway#GO:0030177;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;vesicle organization#GO:0016050;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;canonical Wnt signaling pathway#GO:0060070;regulation of cellular protein catabolic process#GO:1903362;signaling#GO:0023052;cell-cell signaling#GO:0007267;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;Wnt signaling pathway#GO:0016055;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;vesicle budding from membrane#GO:0006900;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;CCKR signaling map#P06959>CK1delta/epsilon#P07089;Hedgehog signaling pathway#P00025>Casein kinase I#P00681;Circadian clock system#P00015>Casein kinase I#P00502;Parkinson disease#P00049>Casein kinase I#P01242 HUMAN|HGNC=23377|UniProtKB=Q5VW36 Q5VW36 FOCAD PTHR16212:SF4 FOCADHESIN FAMILY MEMBER FOCADHESIN HUMAN|HGNC=28149|UniProtKB=Q9BU68 Q9BU68 PRR15L PTHR14581:SF5 FAMILY NOT NAMED PROLINE-RICH PROTEIN 15-LIKE PROTEIN HUMAN|HGNC=24879|UniProtKB=Q6UY09 Q6UY09 CEACAM20 PTHR44427:SF7 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 20 HUMAN|HGNC=15660|UniProtKB=A8MWL7 A8MWL7 TMEM14DP PTHR12668:SF34 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14DP localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;transport#GO:0006810 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 HUMAN|HGNC=20147|UniProtKB=Q7L1T6 Q7L1T6 CYB5R4 PTHR46237:SF1 CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER CYTOCHROME B5 REDUCTASE 4 tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 oxidation-reduction process#GO:0055114;metabolic process#GO:0008152 reductase#PC00198 HUMAN|HGNC=28836|UniProtKB=Q9H019 Q9H019 MTFR1L PTHR14215:SF3 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 1-LIKE cellular component organization or biogenesis#GO:0071840;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organelle organization#GO:0006996;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;organelle fission#GO:0048285;cellular metabolic process#GO:0044237;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial fission#GO:0000266;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6814|UniProtKB=Q9UJ55 Q9UJ55 MAGEL2 PTHR11736:SF66 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MAGE-LIKE PROTEIN 2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=1839|UniProtKB=Q9NZK5 Q9NZK5 ADA2 PTHR11409:SF39 ADENOSINE DEAMINASE ADENOSINE DEAMINASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine-containing compound metabolic process#GO:0072521;pigment biosynthetic process#GO:0046148;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase biosynthetic process#GO:0009113;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 deaminase#PC00088 HUMAN|HGNC=21349|UniProtKB=Q5SZD4 Q5SZD4 GLYATL3 PTHR15298:SF6 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 3 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acyltransferase#PC00042 HUMAN|HGNC=34296|UniProtKB=Q05C16 Q05C16 LRRC63 PTHR45752:SF21 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 63 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 scaffold/adaptor protein#PC00226 HUMAN|HGNC=7787|UniProtKB=Q16649 Q16649 NFIL3 PTHR15284:SF1 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN cellular aromatic compound metabolic process#GO:0006725;rhythmic process#GO:0048511;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;circadian rhythm#GO:0007623;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=8770|UniProtKB=Q13371 Q13371 PDCL PTHR46052:SF4 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN-LIKE PROTEIN HUMAN|HGNC=20765|UniProtKB=Q6PEY2 Q6PEY2 TUBA3E PTHR11588:SF322 TUBULIN TUBULIN ALPHA-3C CHAIN-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 HUMAN|HGNC=28682|UniProtKB=Q8N141 Q8N141 ZFP82 PTHR24377:SF734 IP01015P-RELATED ZINC FINGER PROTEIN 82 HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=21769|UniProtKB=Q9UFC0 Q9UFC0 LRWD1 PTHR24370:SF10 OPTICIN LEUCINE-RICH REPEAT AND WD REPEAT-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102 HUMAN|HGNC=751|UniProtKB=O95671 O95671 ASMTL PTHR43213:SF5 BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphate diphosphatase activity#GO:0047429;catalytic activity#GO:0003824 HUMAN|HGNC=4838|UniProtKB=P05546 P05546 SERPIND1 PTHR11461:SF30 SERINE PROTEASE INHIBITOR, SERPIN HEPARIN COFACTOR 2 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>HCII#P00456 HUMAN|HGNC=948|UniProtKB=O94812 O94812 BAIAP3 PTHR45999:SF1 UNC-13-4A, ISOFORM B BAI1-ASSOCIATED PROTEIN 3 HUMAN|HGNC=13007|UniProtKB=Q9UL58 Q9UL58 ZNF215 PTHR23226:SF65 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 215 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=8105|UniProtKB=P0CE72 P0CE72 OCM PTHR11653:SF16 PARVALBUMIN ALPHA ONCOMODULIN-1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 calmodulin-related#PC00061 HUMAN|HGNC=7327|UniProtKB=O15457 O15457 MSH4 PTHR11361:SF21 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER MUTS PROTEIN HOMOLOG 4 pyrophosphatase activity#GO:0016462;mismatched DNA binding#GO:0030983;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;double-stranded DNA binding#GO:0003690;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;mismatch repair#GO:0006298;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;meiotic chromosome separation#GO:0051307;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;homologous recombination#GO:0035825;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;mismatch repair complex#GO:0032300;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA repair complex#GO:1990391;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 DNA metabolism protein#PC00009 HUMAN|HGNC=9952|UniProtKB=P48304 P48304 REG1B PTHR22803:SF129 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED LITHOSTATHINE-1-BETA carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;carbohydrate binding#GO:0030246;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 response to organic substance#GO:0010033;response to external biotic stimulus#GO:0043207;response to oxygen-containing compound#GO:1901700;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;response to peptide hormone#GO:0043434;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;positive regulation of cell population proliferation#GO:0008284;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;response to organonitrogen compound#GO:0010243;cell population proliferation#GO:0008283;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to biotic stimulus#GO:0009607;response to chemical#GO:0042221;response to peptide#GO:1901652;antimicrobial humoral response#GO:0019730;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=26505|UniProtKB=Q3MIT2 Q3MIT2 PUS10 PTHR21568:SF0 UNCHARACTERIZED TRNA PSEUDOURIDINE SYNTHASE PUS10 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=15375|UniProtKB=Q8N0Y3 Q8N0Y3 OR4N4 PTHR48002:SF4 OLFACTORY RECEPTOR OLFACTORY RECEPTOR-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=12786|UniProtKB=O00755 O00755 WNT7A PTHR12027:SF78 WNT RELATED PROTEIN WNT-7A receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cell fate commitment#GO:0045165;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;generation of neurons#GO:0048699;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=30321|UniProtKB=Q6WCQ1 Q6WCQ1 MPRIP PTHR17271:SF9 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN MYOSIN PHOSPHATASE RHO-INTERACTING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=16403|UniProtKB=Q9UL40 Q9UL40 ZNF346 PTHR46144:SF5 ZINC FINGER PROTEIN 385B-LIKE ZINC FINGER PROTEIN 346 HUMAN|HGNC=15963|UniProtKB=Q15825 Q15825 CHRNA6 PTHR18945:SF82 NEUROTRANSMITTER GATED ION CHANNEL NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotine pharmacodynamics pathway#P06587>CHRNA6#P06592;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=15482|UniProtKB=Q96PQ1 Q96PQ1 SIGLEC12 PTHR12035:SF53 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 12 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=8139|UniProtKB=O95948 O95948 ONECUT2 PTHR14057:SF10 TRANSCRIPTION FACTOR ONECUT ONE CUT DOMAIN FAMILY MEMBER 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=17903|UniProtKB=Q9NPJ6 Q9NPJ6 MED4 PTHR13208:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 general transcription factor#PC00259 HUMAN|HGNC=28100|UniProtKB=Q8N4V1 Q8N4V1 MMGT1 PTHR21181:SF7 FAMILY NOT NAMED MEMBRANE MAGNESIUM TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;cation transmembrane transporter activity#GO:0008324 membrane protein complex#GO:0098796;ER membrane protein complex#GO:0072546;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;early endosome#GO:0005769;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=16235|UniProtKB=Q9H3Z4 Q9H3Z4 DNAJC5 PTHR44027:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5 chaperone#PC00072 HUMAN|HGNC=8124|UniProtKB=Q02218 Q02218 OGDH PTHR23152:SF7 2-OXOGLUTARATE DEHYDROGENASE 2-OXOGLUTARATE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;oxidoreductase complex#GO:1990204;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 TCA cycle#P00051>alphaketoglutarate Dehydrogenase#P01269 HUMAN|HGNC=25980|UniProtKB=Q9NXH9 Q9NXH9 TRMT1 PTHR10631:SF3 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA methyltransferase#PC00033 HUMAN|HGNC=8977|UniProtKB=O00329 O00329 PIK3CD PTHR10048:SF35 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;phosphatidylinositol-mediated signaling#GO:0048015;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;phosphatidylinositol 3-kinase signaling#GO:0014065;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;inositol lipid-mediated signaling#GO:0048017;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477;locomotion#GO:0040011;phosphatidylinositol phosphorylation#GO:0046854 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;Endothelin signaling pathway#P00019>PI3K#P00577;Integrin signalling pathway#P00034>PI3K#P00936;Angiogenesis#P00005>PI3K#P00236;B cell activation#P00010>PI3K#P00391;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;p53 pathway#P00059>PI3K#P04609;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900 HUMAN|HGNC=19884|UniProtKB=Q9UJC3 Q9UJC3 HOOK1 PTHR18947:SF36 HOOK PROTEINS PROTEIN HOOK HOMOLOG 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 membrane traffic protein#PC00150 HUMAN|HGNC=23339|UniProtKB=Q9BR61 Q9BR61 ACBD6 PTHR24119:SF8 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 HUMAN|HGNC=26835|UniProtKB=Q8N8A8 Q8N8A8 FAM169B PTHR22442:SF4 UNCHARACTERIZED PROTEIN FAM169B HUMAN|HGNC=30660|UniProtKB=Q9UBE0 Q9UBE0 SAE1 PTHR10953:SF201 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 1 ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 HUMAN|HGNC=25106|UniProtKB=A4D1E9 A4D1E9 GTPBP10 PTHR11702:SF40 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED GTP-BINDING PROTEIN 10 HUMAN|HGNC=9330|UniProtKB=O60828 O60828 PQBP1 PTHR21737:SF3 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 POLYGLUTAMINE-BINDING PROTEIN 1 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15479|UniProtKB=Q8TC27 Q8TC27 ADAM32 PTHR11905:SF24 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 32 cell recognition#GO:0008037;fertilization#GO:0009566;reproduction#GO:0000003;single fertilization#GO:0007338;biological adhesion#GO:0022610;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell adhesion#GO:0007155;sperm-egg recognition#GO:0035036;cellular process#GO:0009987;multi-organism reproductive process#GO:0044703;multi-organism process#GO:0051704;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=15024|UniProtKB=Q96R54 Q96R54 OR14A2 PTHR26452:SF51 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14A2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=39814|UniProtKB=P0DP73 P0DP73 DEFB130B PTHR20515:SF1 BETA-DEFENSIN BETA-DEFENSIN 130A-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;interspecies interaction between organisms#GO:0044419;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;localization#GO:0051179;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;response to chemical#GO:0042221;defense response to other organism#GO:0098542;response to other organism#GO:0051707;movement of cell or subcellular component#GO:0006928;defense response#GO:0006952;cell migration#GO:0016477;locomotion#GO:0040011;chemotaxis#GO:0006935;taxis#GO:0042330 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=30750|UniProtKB=Q9BVW5 Q9BVW5 TIPIN PTHR13220:SF12 TIMELESS INTERACTING-RELATED TIMELESS-INTERACTING PROTEIN heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;negative regulation of DNA replication#GO:0008156;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;DNA replication checkpoint#GO:0000076;regulation of macromolecule metabolic process#GO:0060255;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;regulation of cell cycle#GO:0051726;DNA replication#GO:0006260;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;pre-replicative complex#GO:0036387;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;MCM complex#GO:0042555;CMG complex#GO:0071162;cellular anatomical entity#GO:0110165;organelle#GO:0043226;replication fork protection complex#GO:0031298;intracellular organelle#GO:0043229;nuclear pre-replicative complex#GO:0005656;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nuclear replication fork#GO:0043596;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;replication fork#GO:0005657 DNA metabolism protein#PC00009 HUMAN|HGNC=37168|UniProtKB=S4R3Y5 S4R3Y5 MTRNR2L11 PTHR33895:SF16 HUMANIN-LIKE 4 HUMANIN-LIKE 11 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=9670|UniProtKB=P10586 P10586 PTPRF PTHR19134:SF203 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE F hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=6091|UniProtKB=P06213 P06213 INSR PTHR24416:SF535 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;peptide hormone binding#GO:0017046;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;inositol lipid-mediated signaling#GO:0048017;protein kinase B signaling#GO:0043491;positive regulation of protein kinase B signaling#GO:0051897;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;phosphatidylinositol-mediated signaling#GO:0048015;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;chemical homeostasis#GO:0048878;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;phosphatidylinositol 3-kinase signaling#GO:0014065;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of phosphatidylinositol 3-kinase signaling#GO:0014066;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of protein kinase B signaling#GO:0051896 membrane protein complex#GO:0098796;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;integral component of membrane#GO:0016021;axon#GO:0030424;transferase complex, transferring phosphorus-containing groups#GO:0061695;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>IR#P06802;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;PI3 kinase pathway#P00048>IR#P01187;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882 HUMAN|Ensembl=ENSG00000283516|UniProtKB=A0A1B0GVX0 A0A1B0GVX0 LITAFD PTHR23292:SF27 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR LITAF DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=15797|UniProtKB=Q4VXU2 Q4VXU2 PABPC1L PTHR24012:SF466 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1-LIKE nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=17587|UniProtKB=Q9Y6C9 Q9Y6C9 MTCH2 PTHR10780:SF20 MITOCHONDRIAL CARRIER HOMOLOG MITOCHONDRIAL CARRIER HOMOLOG 2 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 mitochondrial carrier protein#PC00158 HUMAN|HGNC=49897|UniProtKB=Q6A1A2 Q6A1A2 PDPK2P PTHR24356:SF163 SERINE/THREONINE-PROTEIN KINASE 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PDK1#P00831;Ras Pathway#P04393>PDK#P04555;CCKR signaling map#P06959>PDPK1#P07162;PI3 kinase pathway#P00048>PDK1 ACT#P01190;PI3 kinase pathway#P00048>PDK1#P01196;p53 pathway feedback loops 2#P04398>PDK1/2#P04656;p53 pathway#P00059>PDK1/2#P04616;Interleukin signaling pathway#P00036>PDK1/2#P00985;PDGF signaling pathway#P00047>PDK1/2#P01164;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PDK1/2#P00903;PI3 kinase pathway#P00048>P110ACT#P01177 HUMAN|HGNC=25555|UniProtKB=Q9NVN3 Q9NVN3 RIC8B PTHR12425:SF2 SYNEMBRYN SYNEMBRYN-B GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 HUMAN|HGNC=3263|UniProtKB=Q9UKV8 Q9UKV8 AGO2 PTHR22891:SF59 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-2 translation initiation factor#PC00224 HUMAN|HGNC=8784|UniProtKB=O76074 O76074 PDE5A PTHR11347:SF20 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-GMP phosphodiesterase activity#GO:0047555;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 phosphodiesterase#PC00185 HUMAN|HGNC=29401|UniProtKB=Q5VVJ2 Q5VVJ2 MYSM1 PTHR12802:SF67 SWI/SNF COMPLEX-RELATED HISTONE H2A DEUBIQUITINASE MYSM1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=4065|UniProtKB=P10253 P10253 GAA PTHR22762:SF92 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE glucosidase#PC00108 HUMAN|HGNC=15378|UniProtKB=Q8NGE3 Q8NGE3 OR10P1 PTHR26453:SF194 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10P1 transmembrane signal receptor#PC00197 HUMAN|HGNC=2158|UniProtKB=P09543 P09543 CNP PTHR10156:SF0 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phosphodiesterase#PC00185 HUMAN|HGNC=24856|UniProtKB=Q96A33 Q96A33 CCDC47 PTHR12883:SF0 ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 47 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=6446|UniProtKB=P05787 P05787 KRT8 PTHR45616:SF26 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 8 HUMAN|HGNC=12457|UniProtKB=Q16222 Q16222 UAP1 PTHR11952:SF4 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLHEXOSAMINE PYROPHOSPHORYLASE transferase activity, transferring phosphorus-containing groups#GO:0016772;uridylyltransferase activity#GO:0070569;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;UDP-N-acetylglucosamine metabolic process#GO:0006047;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;amino sugar metabolic process#GO:0006040;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 HUMAN|HGNC=15784|UniProtKB=Q96C45 Q96C45 ULK4 PTHR46240:SF1 SER/THR PROTEIN KINASE ULK4 SERINE/THREONINE-PROTEIN KINASE ULK4 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=1594|UniProtKB=P51946 P51946 CCNH PTHR10026:SF8 CYCLIN CYCLIN-H cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;phosphorylation of RNA polymerase II C-terminal domain#GO:0070816;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;regulation of phosphate metabolic process#GO:0019220;regulation of cyclin-dependent protein kinase activity#GO:1904029;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;nucleic acid-templated transcription#GO:0097659;regulation of protein kinase activity#GO:0045859;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;regulation of transferase activity#GO:0051338;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675 kinase activator#PC00138 HUMAN|HGNC=9293|UniProtKB=Q9UQK1 Q9UQK1 PPP1R3C PTHR12307:SF15 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3C phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase 1 binding#GO:0008157;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 monosaccharide metabolic process#GO:0005996;glucan metabolic process#GO:0044042;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;energy derivation by oxidation of organic compounds#GO:0015980;regulation of biological process#GO:0050789;cellular glucan metabolic process#GO:0006073;glucan biosynthetic process#GO:0009250;regulation of biosynthetic process#GO:0009889;oxidation-reduction process#GO:0055114;regulation of macromolecule biosynthetic process#GO:0010556;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;glycogen biosynthetic process#GO:0005978;regulation of glucose metabolic process#GO:0010906;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;polysaccharide metabolic process#GO:0005976;regulation of cellular biosynthetic process#GO:0031326;cellular carbohydrate metabolic process#GO:0044262;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;hexose metabolic process#GO:0019318;energy reserve metabolic process#GO:0006112;cellular polysaccharide biosynthetic process#GO:0033692;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular polysaccharide metabolic process#GO:0044264;small molecule metabolic process#GO:0044281 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 phosphatase modulator#PC00184 HUMAN|HGNC=11329|UniProtKB=P61278 P61278 SST PTHR10558:SF2 SOMATOSTATIN SOMATOSTATIN localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cellular component movement#GO:0051270;regulation of cell migration#GO:0030334;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;regulation of localization#GO:0032879;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 HUMAN|HGNC=17016|UniProtKB=O95251 O95251 KAT7 PTHR10615:SF102 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT7 molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137 HUMAN|HGNC=23612|UniProtKB=Q6ZQN7 Q6ZQN7 SLCO4C1 PTHR11388:SF103 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 4C1 secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=30476|UniProtKB=Q8WXB1 Q8WXB1 METTL21A PTHR14614:SF14 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN N-LYSINE METHYLTRANSFERASE METTL21A N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein alkylation#GO:0008213;protein methylation#GO:0006479;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=18200|UniProtKB=Q8WXE0 Q8WXE0 CASKIN2 PTHR24177:SF37 CASKIN CASKIN-2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26194|UniProtKB=Q6ZVK8 Q6ZVK8 NUDT18 PTHR22769:SF56 MUTT/NUDIX HYDROLASE 8-OXO-DGDP PHOSPHATASE NUDT18 hydrolase#PC00121 HUMAN|HGNC=33713|UniProtKB=A6NEN9 A6NEN9 CXorf65 PTHR33887:SF4 FAMILY NOT NAMED SI:CH211-191O15.6 HUMAN|HGNC=32550|UniProtKB=B2RXF5 B2RXF5 ZBTB42 PTHR24394:SF20 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 42 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23729|UniProtKB=Q8IYA7 Q8IYA7 MKX PTHR11211:SF3 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX HOMEOBOX PROTEIN MOHAWK cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=21624|UniProtKB=Q9NSK0 Q9NSK0 KLC4 PTHR45783:SF6 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 4 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 HUMAN|HGNC=2746|UniProtKB=P17844 P17844 DDX5 PTHR47958:SF90 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX5-RELATED catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11065|UniProtKB=Q9UM01 Q9UM01 SLC7A7 PTHR11785:SF303 AMINO ACID TRANSPORTER Y+L AMINO ACID TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 regulation of nitrogen compound metabolic process#GO:0051171;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;anion transport#GO:0006820;alpha-amino acid metabolic process#GO:1901605;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ion transmembrane transport#GO:0034220;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;organic acid transmembrane transport#GO:1903825;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323 transporter#PC00227 HUMAN|HGNC=30840|UniProtKB=Q7Z3Y9 Q7Z3Y9 KRT26 PTHR23239:SF162 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 26 HUMAN|HGNC=2974|UniProtKB=P50570 P50570 DNM2 PTHR11566:SF23 DYNAMIN DYNAMIN-2 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;membrane organization#GO:0061024;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;membrane fission#GO:0090148;vesicle localization#GO:0051648;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;protein transport#GO:0015031;biological regulation#GO:0065007;protein polymerization#GO:0051258;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;regulation of synapse structure or activity#GO:0050803;mitochondrial fission#GO:0000266;vesicle-mediated transport in synapse#GO:0099003;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;non-membrane-bounded organelle#GO:0043228;membrane coat#GO:0030117;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;mitochondrial envelope#GO:0005740;plasma membrane region#GO:0098590;postsynapse#GO:0098794;coated membrane#GO:0048475;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;envelope#GO:0031975;membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;mitochondrial membrane#GO:0031966;intracellular vesicle#GO:0097708;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;mitochondrion#GO:0005739;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=29529|UniProtKB=Q9BZK7 Q9BZK7 TBL1XR1 PTHR22846:SF40 WD40 REPEAT PROTEIN F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1XR1 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;protein deacetylation#GO:0006476;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Wnt signaling pathway#P00057>Ebi#P01453 HUMAN|HGNC=26721|UniProtKB=Q86TB9 Q86TB9 PATL1 PTHR21551:SF2 TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1 PROTEIN PAT1 HOMOLOG 1 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;deadenylation-dependent decapping of nuclear-transcribed mRNA#GO:0000290;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cytoplasmic mRNA processing body assembly#GO:0033962;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147 HUMAN|HGNC=33887|UniProtKB=Q8TBR4 Q8TBR4 STAG3L4 PTHR11199:SF6 STROMAL ANTIGEN COHESIN SUBUNIT SA-1-RELATED binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;chromatin#GO:0000785;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=13480|UniProtKB=Q8IYT8 Q8IYT8 ULK2 PTHR24348:SF18 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE/THREONINE-PROTEIN KINASE ULK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;growth#GO:0040007;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;axon extension#GO:0048675;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular protein metabolic process#GO:0044267;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;developmental cell growth#GO:0048588;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;cell morphogenesis involved in differentiation#GO:0000904;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cell growth#GO:0016049;cellular component morphogenesis#GO:0032989;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=19973|UniProtKB=Q8TCX5 Q8TCX5 RHPN1 PTHR23031:SF6 RHOPHILIN RHOPHILIN-1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=43653|UniProtKB=O95073 O95073 FSBP PTHR15386:SF0 FIBRINOGEN SILENCER-BINDING PROTEIN FIBRINOGEN SILENCER-BINDING PROTEIN HUMAN|HGNC=30621|UniProtKB=Q9H2V7 Q9H2V7 SPNS1 PTHR23505:SF13 SPINSTER PROTEIN SPINSTER HOMOLOG 1 transporter#PC00227 HUMAN|HGNC=3608|UniProtKB=P24071 P24071 FCAR PTHR11738:SF4 MHC CLASS I NK CELL RECEPTOR IMMUNOGLOBULIN ALPHA FC RECEPTOR immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=8252|UniProtKB=Q9GZK4 Q9GZK4 OR2H1 PTHR26453:SF323 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2H1 transmembrane signal receptor#PC00197 HUMAN|HGNC=25185|UniProtKB=Q6NXT1 Q6NXT1 ANKRD54 PTHR24197:SF47 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 54 HUMAN|HGNC=24910|UniProtKB=Q9NWL6 Q9NWL6 ASNSD1 PTHR45937:SF1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=7795|UniProtKB=Q00653 Q00653 NFKB2 PTHR24169:SF21 NUCLEAR FACTOR NF-KAPPA-B PROTEIN NUCLEAR FACTOR NF-KAPPA-B P100 SUBUNIT cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;B cell activation#P00010>NFkappaB#P00370;T cell activation#P00053>NFkappaB#P01298;Toll receptor signaling pathway#P00054>NFkappaB#P01354;Apoptosis signaling pathway#P00006>NFkappaB#P00297 HUMAN|HGNC=13008|UniProtKB=O76080 O76080 ZFAND5 PTHR10634:SF26 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 5 HUMAN|HGNC=14566|UniProtKB=Q9H1H9 Q9H1H9 KIF13A PTHR24115:SF458 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF13A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=16812|UniProtKB=Q8NI60 Q8NI60 COQ8A PTHR43851:SF1 FAMILY NOT NAMED ATYPICAL KINASE COQ8A, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;small molecule biosynthetic process#GO:0044283;ubiquinone biosynthetic process#GO:0006744;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=6287|UniProtKB=Q9NPA1 Q9NPA1 KCNMB3 PTHR10258:SF4 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;transporter activity#GO:0005215;channel activity#GO:0015267;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 response to metal ion#GO:0010038;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to inorganic substance#GO:0010035;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=11509|UniProtKB=P21579 P21579 SYT1 PTHR10024:SF239 SYNAPTOTAGMIN SYNAPTOTAGMIN-1 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;syntaxin binding#GO:0019905;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;synaptic signaling#GO:0099536;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;neurotransmitter secretion#GO:0007269;response to inorganic substance#GO:0010035;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;exocytic process#GO:0140029;cellular component organization or biogenesis#GO:0071840;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;regulation of neurotransmitter levels#GO:0001505;regulation of ion transport#GO:0043269;export from cell#GO:0140352;vesicle fusion#GO:0006906;regulation of signaling#GO:0023051;transport#GO:0006810;cation transport#GO:0006812;organic substance transport#GO:0071702;regulation of transport#GO:0051049;neurotransmitter transport#GO:0006836;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;response to metal ion#GO:0010038;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;response to chemical#GO:0042221;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 HUMAN|HGNC=27274|UniProtKB=Q5T292 Q5T292 TMEM273 PTHR37857:SF1 TRANSMEMBRANE PROTEIN 273 TRANSMEMBRANE PROTEIN 273 HUMAN|HGNC=4584|UniProtKB=Q05586 Q05586 GRIN1 PTHR18966:SF377 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;signaling receptor activity#GO:0038023;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;molecular transducer activity#GO:0060089;transporter activity#GO:0005215;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Ionotropic glutamate receptor pathway#P00037>NR1#P01010;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 HUMAN|HGNC=20749|UniProtKB=Q5W0Z9 Q5W0Z9 ZDHHC20 PTHR22883:SF417 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC20 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;developmental process#GO:0032502;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;vesicle organization#GO:0016050;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;cellular process#GO:0009987;peptide transport#GO:0015833;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=25860|UniProtKB=Q8TAY7 Q8TAY7 FAM110D PTHR14758:SF3 AGAP005440-PA PROTEIN FAM110D HUMAN|HGNC=4544|UniProtKB=P34947 P34947 GRK5 PTHR24355:SF27 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 5 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK5#P05940;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701 HUMAN|HGNC=30388|UniProtKB=A5D8T8 A5D8T8 CLEC18A PTHR10334:SF521 CYSTEINE-RICH SECRETORY PROTEIN-RELATED C-TYPE LECTIN DOMAIN FAMILY 18 MEMBER A-RELATED extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=28684|UniProtKB=Q8N587 Q8N587 ZNF561 PTHR24377:SF948 IP01015P-RELATED ZINC FINGER PROTEIN 561 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25013|UniProtKB=Q9P003 Q9P003 CNIH4 PTHR12290:SF19 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 4 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 HUMAN|HGNC=20498|UniProtKB=Q7Z3D6 Q7Z3D6 DGLUCY PTHR32022:SF10 D-GLUTAMATE CYCLASE, MITOCHONDRIAL D-GLUTAMATE CYCLASE, MITOCHONDRIAL cyclase#PC00079 HUMAN|HGNC=9617|UniProtKB=Q13882 Q13882 PTK6 PTHR24418:SF265 TYROSINE-PROTEIN KINASE PROTEIN-TYROSINE KINASE 6 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell population proliferation#GO:0008283;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;innate immune response#GO:0045087;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;peptidyl-tyrosine modification#GO:0018212;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 HUMAN|HGNC=11064|UniProtKB=Q92536 Q92536 SLC7A6 PTHR11785:SF398 AMINO ACID TRANSPORTER Y+L AMINO ACID TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 transporter#PC00227 HUMAN|HGNC=10934|UniProtKB=P54219 P54219 SLC18A1 PTHR23506:SF31 FAMILY NOT NAMED CHROMAFFIN GRANULE AMINE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;symporter activity#GO:0015293;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;sodium:chloride symporter activity#GO:0015378;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;metal ion transmembrane transporter activity#GO:0046873;monoamine transmembrane transporter activity#GO:0008504;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic substance transport#GO:0071702;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;neurotransmitter transport#GO:0006836;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;terminal bouton#GO:0043195;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418;5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410 HUMAN|HGNC=29253|UniProtKB=Q9P2K1 Q9P2K1 CC2D2A PTHR20837:SF7 CENTROSOMAL PROTEIN-RELATED COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 2A HUMAN|HGNC=4475|UniProtKB=Q99678 Q99678 GPR20 PTHR24232:SF7 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 20 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=3816|UniProtKB=Q92949 Q92949 FOXJ1 PTHR46805:SF1 FORKHEAD BOX PROTEIN J1 FORKHEAD BOX PROTEIN J1 HUMAN|HGNC=18431|UniProtKB=P49753 P49753 ACOT2 PTHR10824:SF16 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COENZYME A THIOESTERASE 1-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 esterase#PC00097 HUMAN|HGNC=19653|UniProtKB=Q7RTT5 Q7RTT5 SSX7 PTHR14112:SF24 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX7-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=21556|UniProtKB=Q5TFE4 Q5TFE4 NT5DC1 PTHR12103:SF12 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173 HUMAN|HGNC=1308|UniProtKB=Q9Y3P4 Q9Y3P4 RHBDD3 PTHR43066:SF16 RHOMBOID-RELATED PROTEIN RHOMBOID DOMAIN-CONTAINING PROTEIN 3 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 HUMAN|HGNC=9541|UniProtKB=P28070 P28070 PSMB4 PTHR11599:SF5 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-4 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=28627|UniProtKB=Q8N4U5 Q8N4U5 TCP11L2 PTHR12832:SF17 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11-LIKE PROTEIN 2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=13031|UniProtKB=Q16600 Q16600 ZNF239 PTHR23226:SF189 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 239 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7228|UniProtKB=P22897 P22897 MRC1 PTHR22803:SF104 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED MACROPHAGE MANNOSE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=21044|UniProtKB=Q9BZ72 Q9BZ72 PITPNM2 PTHR10658:SF41 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN MEMBRANE-ASSOCIATED PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 2 cation binding#GO:0043169;phosphatidylcholine binding#GO:0031210;binding#GO:0005488;phosphatidylcholine transporter activity#GO:0008525;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transporter#PC00227 HUMAN|HGNC=14271|UniProtKB=Q86WH2 Q86WH2 RASSF3 PTHR22738:SF8 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 3 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9042|UniProtKB=Q13018 Q13018 PLA2R1 PTHR22803:SF74 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED SECRETORY PHOSPHOLIPASE A2 RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 receptor complex#GO:0043235;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=17717|UniProtKB=Q9UEW8 Q9UEW8 STK39 PTHR48012:SF14 STERILE20-LIKE KINASE, ISOFORM B-RELATED STE20/SPS1-RELATED PROLINE-ALANINE-RICH PROTEIN KINASE HUMAN|HGNC=9082|UniProtKB=O00469 O00469 PLOD2 PTHR10730:SF6 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE 2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=25526|UniProtKB=Q86YD7 Q86YD7 FAM90A1 PTHR16035:SF16 PROTEIN FAM90A1 PROTEIN FAM90A1-RELATED HUMAN|HGNC=6622|UniProtKB=P07098 P07098 LIPF PTHR11005:SF15 LYSOSOMAL ACID LIPASE-RELATED GASTRIC TRIACYLGLYCEROL LIPASE membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 lipase#PC00143 HUMAN|HGNC=1795|UniProtKB=Q16878 Q16878 CDO1 PTHR12918:SF1 CYSTEINE DIOXYGENASE CYSTEINE DIOXYGENASE TYPE 1 cation binding#GO:0043169;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;ferrous iron binding#GO:0008198;binding#GO:0005488;catalytic activity#GO:0003824;iron ion binding#GO:0005506;dioxygenase activity#GO:0051213;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxygenase#PC00177 HUMAN|HGNC=20443|UniProtKB=O43312 O43312 MTSS1 PTHR15708:SF10 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED PROTEIN MTSS 1 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=10348|UniProtKB=P61513 P61513 RPL37A PTHR48160:SF1 FAMILY NOT NAMED 60S RIBOSOMAL PROTEIN L37A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 HUMAN|HGNC=24814|UniProtKB=A8MYZ6 A8MYZ6 FOXO6 PTHR45767:SF5 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O3B-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=21916|UniProtKB=Q4G0A6 Q4G0A6 MINDY4 PTHR12473:SF13 UNCHARACTERIZED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 HUMAN|HGNC=6697|UniProtKB=O75197 O75197 LRP5 PTHR46513:SF16 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 5-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>LRP5/6#P01431;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 HUMAN|HGNC=37295|UniProtKB=A4D2H0 A4D2H0 CTAGE15 PTHR23158:SF57 MELANOMA INHIBITORY ACTIVITY-RELATED CTAGE FAMILY MEMBER 15-RELATED endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=29486|UniProtKB=Q6UWN8 Q6UWN8 SPINK6 PTHR10913:SF13 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 1-RELATED signal transduction#GO:0007165;response to growth factor#GO:0070848;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;signaling#GO:0023052;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=22220|UniProtKB=Q6ECI4 Q6ECI4 ZNF470 PTHR24377:SF282 IP01015P-RELATED ZINC FINGER PROTEIN 470 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=13302|UniProtKB=Q9BZJ6 Q9BZJ6 GPR63 PTHR24245:SF1 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 63-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=1833|UniProtKB=P49715 P49715 CEBPA PTHR23334:SF5 CCAAT/ENHANCER BINDING PROTEIN CCAAT/ENHANCER-BINDING PROTEIN ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;myeloid cell differentiation#GO:0030099;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=10055|UniProtKB=Q8N5U6 Q8N5U6 RNF10 PTHR12983:SF9 RING FINGER 10 FAMILY MEMBER RING FINGER PROTEIN 10 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 HUMAN|HGNC=26010|UniProtKB=Q96EA4 Q96EA4 SPDL1 PTHR32123:SF9 BICD FAMILY-LIKE CARGO ADAPTER PROTEIN SPINDLY binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;nuclear division#GO:0000280;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;establishment of cell polarity#GO:0030010;metaphase plate congression#GO:0051310;mitotic cell cycle#GO:0000278;protein localization to kinetochore#GO:0034501;establishment of localization#GO:0051234;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;establishment of chromosome localization#GO:0051303;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;establishment of mitotic spindle orientation#GO:0000132;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;mitotic metaphase plate congression#GO:0007080;chromosome localization#GO:0050000 supramolecular complex#GO:0099080;spindle pole#GO:0000922;kinetochore#GO:0000776;condensed chromosome kinetochore#GO:0000777;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;condensed chromosome outer kinetochore#GO:0000940;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=4747|UniProtKB=P58876 P58876 H2BC5 PTHR23428:SF245 HISTONE H2B HISTONE H2B TYPE 1-D nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=27266|UniProtKB=Q3SY77 Q3SY77 UGT3A2 PTHR48043:SF24 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 3A2 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=30231|UniProtKB=O75663 O75663 TIPRL PTHR21021:SF16 GAF/PUTATIVE CYTOSKELETAL PROTEIN TIP41-LIKE PROTEIN oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 signal transduction#GO:0007165;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;regulation of phosphoprotein phosphatase activity#GO:0043666;TOR signaling#GO:0031929;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of phosphatase activity#GO:0010921;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=12423|UniProtKB=O00294 O00294 TULP1 PTHR16517:SF12 TUBBY-RELATED TUBBY-RELATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;cellular protein localization#GO:0034613;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=6595|UniProtKB=Q9UBR4 Q9UBR4 LHX3 PTHR24208:SF91 LIM/HOMEOBOX PROTEIN LHX LIM/HOMEOBOX PROTEIN LHX3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=326|UniProtKB=Q9NRZ7 Q9NRZ7 AGPAT3 PTHR10983:SF9 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GAMMA transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=11016|UniProtKB=O15431 O15431 SLC31A1 PTHR12483:SF22 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS HIGH AFFINITY COPPER UPTAKE PROTEIN 1 secondary carrier transporter#PC00258 HUMAN|HGNC=5924|UniProtKB=A0A087WSX0 A0A087WSX0 IGLV5-45 PTHR23267:SF325 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 5-37-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=20669|UniProtKB=Q86VI3 Q86VI3 IQGAP3 PTHR14149:SF10 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP3 GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;GTPase binding#GO:0051020;enzyme binding#GO:0019899;calmodulin binding#GO:0005516;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rho GTPase binding#GO:0017048;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;Rac GTPase binding#GO:0048365;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 GTPase-activating protein#PC00257 HUMAN|HGNC=9283|UniProtKB=P36873 P36873 PPP1CC PTHR11668:SF204 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602;Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969 HUMAN|HGNC=221|UniProtKB=Q9UNA0 Q9UNA0 ADAMTS5 PTHR13723:SF37 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 5 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=23162|UniProtKB=Q5BKT4 Q5BKT4 ALG10 PTHR12989:SF11 ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10 DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=19965|UniProtKB=Q9P2K2 Q9P2K2 TXNDC16 PTHR22699:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 16 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 16 oxidoreductase#PC00176 HUMAN|HGNC=2015|UniProtKB=A8K7I4 A8K7I4 CLCA1 PTHR10579:SF52 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=31822|UniProtKB=Q63HM9 Q63HM9 PLCXD3 PTHR13593:SF33 UNCHARACTERIZED PI-PLC X DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=31909|UniProtKB=P43362 P43362 MAGEA9B PTHR11736:SF62 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 9 scaffold/adaptor protein#PC00226 HUMAN|HGNC=30381|UniProtKB=Q96FV2 Q96FV2 SCRN2 PTHR12994:SF16 SECERNIN SECERNIN-2 HUMAN|HGNC=1664|UniProtKB=Q8WTV0 Q8WTV0 SCARB1 PTHR11923:SF96 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 SCAVENGER RECEPTOR CLASS B MEMBER 1 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=16128|UniProtKB=Q9H3Z7 Q9H3Z7 ABHD16B PTHR12277:SF37 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD16B hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;acylglycerol lipase activity#GO:0047372;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;acylglycerol catabolic process#GO:0046464;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=2260|UniProtKB=Q12887 Q12887 COX10 PTHR43448:SF2 PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;porphyrin-containing compound metabolic process#GO:0006778;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;oxidation-reduction process#GO:0055114;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152 acyltransferase#PC00042 Heme biosynthesis#P02746>Protoheme IX farnesyl transferase#P02982 HUMAN|HGNC=21232|UniProtKB=Q96G30 Q96G30 MRAP2 PTHR28675:SF1 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 molecular function regulator#GO:0098772;protein binding#GO:0005515;receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;protein localization to plasma membrane#GO:0072659;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;protein localization to membrane#GO:0072657;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;regulation of response to stimulus#GO:0048583;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=16934|UniProtKB=Q9BSK4 Q9BSK4 FEM1A PTHR24173:SF12 FAMILY NOT NAMED PROTEIN FEM-1 HOMOLOG A negative regulation of biological process#GO:0048519;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;negative regulation of inflammatory response#GO:0050728;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;defense response#GO:0006952;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular protein catabolic process#GO:0044257;regulation of defense response#GO:0031347;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=20834|UniProtKB=Q86V35 Q86V35 CABP7 PTHR46311:SF1 CALCIUM-BINDING PROTEIN 8-RELATED CALCIUM-BINDING PROTEIN 7 HUMAN|HGNC=18265|UniProtKB=Q96LB4 Q96LB4 ATP6V1G3 PTHR12713:SF5 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G 3 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002 HUMAN|HGNC=10450|UniProtKB=O14718 O14718 RRH PTHR24240:SF77 OPSIN VISUAL PIGMENT-LIKE RECEPTOR PEROPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to abiotic stimulus#GO:0071214;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=33701|UniProtKB=Q5EG05 Q5EG05 CARD16 PTHR47901:SF2 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 16 enzyme binding#GO:0019899;protein binding#GO:0005515;protease binding#GO:0002020;binding#GO:0005488 HUMAN|HGNC=30933|UniProtKB=Q9BXY8 Q9BXY8 BEX2 PTHR19430:SF2 PROTEIN BEX1-RELATED PROTEIN BEX2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28108|UniProtKB=Q9GZT6 Q9GZT6 CCDC90B PTHR14360:SF14 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 90B, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4323|UniProtKB=Q04760 Q04760 GLO1 PTHR10374:SF30 LACTOYLGLUTATHIONE LYASE GLYOXALASE I LACTOYLGLUTATHIONE LYASE lyase#PC00144 HUMAN|HGNC=28867|UniProtKB=Q9Y6M1 Q9Y6M1 IGF2BP2 PTHR10288:SF93 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 regulation of biological process#GO:0050789;system development#GO:0048731;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;anatomical structure development#GO:0048856;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological regulation#GO:0065007;gene expression#GO:0010467;multicellular organismal process#GO:0032501;regulation of gene expression#GO:0010468;nervous system development#GO:0007399;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=2735|UniProtKB=Q13206 Q13206 DDX10 PTHR24031:SF758 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX10-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=15662|UniProtKB=Q9BS86 Q9BS86 ZPBP PTHR15443:SF5 ZONA PELLUCIDA BINDING PROTEIN SP38 ZONA PELLUCIDA-BINDING PROTEIN 1 male gamete generation#GO:0048232;cell recognition#GO:0008037;cellular component biogenesis#GO:0044085;fertilization#GO:0009566;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;endomembrane system organization#GO:0010256;spermatid differentiation#GO:0048515;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;spermatogenesis#GO:0007283;reproductive process#GO:0022414;vesicle organization#GO:0016050;sperm-egg recognition#GO:0035036;multi-organism reproductive process#GO:0044703;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;multi-organism process#GO:0051704;cellular component morphogenesis#GO:0032989;cell-cell recognition#GO:0009988;organelle assembly#GO:0070925;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;spermatid development#GO:0007286;reproduction#GO:0000003;organelle organization#GO:0006996;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501 chaperone complex#GO:0101031;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;chaperonin-containing T-complex#GO:0005832;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=1859|UniProtKB=Q9BV73 Q9BV73 CEP250 PTHR23159:SF1 CENTROSOMAL PROTEIN 2 CENTROSOME-ASSOCIATED PROTEIN CEP250 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=28534|UniProtKB=Q8N5N4 Q8N5N4 C3orf22 PTHR37875:SF1 HYPOTHETICAL PROTEIN LOC685964 HYPOTHETICAL PROTEIN LOC685964 HUMAN|HGNC=28397|UniProtKB=Q8TC56 Q8TC56 FAM71B PTHR22574:SF2 UNCHARACTERIZED PROTEIN FAM71B membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=6225|UniProtKB=P17658 P17658 KCNA6 PTHR11537:SF104 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 6 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=10952|UniProtKB=Q9UIG8 Q9UIG8 SLCO3A1 PTHR11388:SF86 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 3A1 secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;lipid transport#GO:0006869 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=23315|UniProtKB=Q5VYV0 Q5VYV0 FOXB2 PTHR11829:SF215 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN B2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=4577|UniProtKB=A4D1Z8 A4D1Z8 GRIFIN PTHR11346:SF21 GALECTIN GRIFIN extracellular matrix protein#PC00102 HUMAN|HGNC=28335|UniProtKB=Q6ZMR3 Q6ZMR3 LDHAL6A PTHR43128:SF9 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A-LIKE 6A oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092 HUMAN|HGNC=4518|UniProtKB=Q9HB89 Q9HB89 NMUR1 PTHR24243:SF109 G-PROTEIN COUPLED RECEPTOR NEUROMEDIN-U RECEPTOR 1 G-protein coupled receptor#PC00021 HUMAN|HGNC=12269|UniProtKB=Q9NSU2 Q9NSU2 TREX1 PTHR13058:SF27 THREE PRIME REPAIR EXONUCLEASE 1, 2 THREE-PRIME REPAIR EXONUCLEASE 1 3'-5'-exodeoxyribonuclease activity#GO:0008296;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;exodeoxyribonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;exodeoxyribonuclease activity, producing 5'-phosphomonoesters#GO:0016895;deoxyribonuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 HUMAN|HGNC=17142|UniProtKB=Q96CV9 Q96CV9 OPTN PTHR31553:SF2 NF-KAPPA-B ESSENTIAL MODULATOR OPTINEURIN protein binding#GO:0005515;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;endomembrane system organization#GO:0010256;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;Golgi organization#GO:0007030;macromolecule metabolic process#GO:0043170;protein localization to Golgi apparatus#GO:0034067;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;protein localization to organelle#GO:0033365;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 Huntington disease#P00029>FIP-2#P00772 HUMAN|HGNC=3233|UniProtKB=Q7Z7M0 Q7Z7M0 MEGF8 PTHR10574:SF287 NETRIN/LAMININ-RELATED MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 8 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cell morphogenesis involved in differentiation#GO:0000904;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;substrate adhesion-dependent cell spreading#GO:0034446;localization of cell#GO:0051674;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;extracellular matrix organization#GO:0030198;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;cell differentiation#GO:0030154;extracellular structure organization#GO:0043062;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;cell migration#GO:0016477;locomotion#GO:0040011 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 HUMAN|HGNC=10919|UniProtKB=Q15849 Q15849 SLC14A2 PTHR10464:SF6 UREA TRANSPORTER UREA TRANSPORTER 2 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 transporter#PC00227 HUMAN|HGNC=1974|UniProtKB=O15111 O15111 CHUK PTHR22969:SF13 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT ALPHA DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;double-stranded DNA binding#GO:0003690;kinase activity#GO:0016301;protein kinase activity#GO:0004672;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;protein serine/threonine kinase activity#GO:0004674;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;catalytic activity, acting on a protein#GO:0140096 positive regulation of gene expression#GO:0010628;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;tumor necrosis factor-mediated signaling pathway#GO:0033209;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;response to tumor necrosis factor#GO:0034612;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>IKK#P00313;Toll receptor signaling pathway#P00054>IKKalpha#P01345;PDGF signaling pathway#P00047>Ikk#P01146;B cell activation#P00010>IKK#P00397;T cell activation#P00053>IKK#P01330;Interleukin signaling pathway#P00036>Ikk#P00968;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IKK#P00871 HUMAN|HGNC=910|UniProtKB=P25311 P25311 AZGP1 PTHR16675:SF198 MHC CLASS I-RELATED ZINC-ALPHA-2-GLYCOPROTEIN response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=10471|UniProtKB=Q01196 Q01196 RUNX1 PTHR11950:SF40 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;hematopoietic or lymphoid organ development#GO:0048534;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Runt transcription factor#PC00254 HUMAN|HGNC=30026|UniProtKB=Q8TD55 Q8TD55 PLEKHO2 PTHR15871:SF2 PH DOMAIN-CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY O MEMBER 2 HUMAN|HGNC=17704|UniProtKB=Q9UPQ7 Q9UPQ7 PDZRN3 PTHR15545:SF5 PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 E3 UBIQUITIN-PROTEIN LIGASE PDZRN3 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;neuromuscular junction development#GO:0007528;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;nitrogen compound metabolic process#GO:0006807;cell junction organization#GO:0034330;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=25316|UniProtKB=Q5VZ19 Q5VZ19 TDRD10 PTHR22948:SF12 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 10 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17147|UniProtKB=Q9H3Q1 Q9H3Q1 CDC42EP4 PTHR15344:SF14 CDC42 EFFECTOR PROTEIN BORG CDC42 EFFECTOR PROTEIN 4 HUMAN|HGNC=17303|UniProtKB=Q5VWG9 Q5VWG9 TAF3 PTHR46452:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=42|UniProtKB=O95342 O95342 ABCB11 PTHR24221:SF165 ATP-BINDING CASSETTE SUB-FAMILY B BILE SALT EXPORT PUMP pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=32390|UniProtKB=Q6GV28 Q6GV28 TMEM225 PTHR36477:SF1 TRANSMEMBRANE PROTEIN 225 TRANSMEMBRANE PROTEIN 225 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;negative regulation of phosphatase activity#GO:0010923;negative regulation of phosphorus metabolic process#GO:0010563;regulation of phosphatase activity#GO:0010921;regulation of dephosphorylation#GO:0035303;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of catalytic activity#GO:0050790;negative regulation of dephosphorylation#GO:0035305;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of hydrolase activity#GO:0051336;negative regulation of catalytic activity#GO:0043086;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 HUMAN|HGNC=25841|UniProtKB=Q5VT97 Q5VT97 SYDE2 PTHR46150:SF1 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN SYDE2 GTPase-activating protein#PC00257 HUMAN|HGNC=12372|UniProtKB=P01222 P01222 TSHB PTHR11515:SF5 GLYCOPROTEIN HORMONE BETA CHAIN THYROTROPIN SUBUNIT BETA receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular#GO:0005622 peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Thyrotropin#P04588;Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586 HUMAN|HGNC=11593|UniProtKB=O75333 O75333 TBX10 PTHR11267:SF102 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX10 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 specification of symmetry#GO:0009799;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;heart looping#GO:0001947;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;heart development#GO:0007507;embryonic heart tube development#GO:0035050;determination of heart left/right asymmetry#GO:0061371;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;determination of bilateral symmetry#GO:0009855;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;determination of left/right symmetry#GO:0007368;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=2328|UniProtKB=P50416 P50416 CPT1A PTHR22589:SF74 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 1, LIVER ISOFORM transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=12119|UniProtKB=A0A0B4J277 A0A0B4J277 TRAV22 PTHR19339:SF2 T CELL RECEPTOR ALPHA VARIABLE 39 T CELL RECEPTOR ALPHA VARIABLE 22 HUMAN|HGNC=21728|UniProtKB=Q8IU81 Q8IU81 IRF2BP1 PTHR10816:SF17 MYELIN TRANSCRIPTION FACTOR 1-RELATED INTERFERON REGULATORY FACTOR 2-BINDING PROTEIN 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;transcription corepressor activity#GO:0003714 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=28742|UniProtKB=Q6ZNG0 Q6ZNG0 ZNF620 PTHR24381:SF114 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 620 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26302|UniProtKB=Q17RB8 Q17RB8 LONRF1 PTHR23327:SF4 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=15950|UniProtKB=Q9BWW7 Q9BWW7 SCRT1 PTHR24388:SF60 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR SCRATCH 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3267|UniProtKB=P41091 P41091 EIF2S3 PTHR42854:SF14 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;heterocyclic compound binding#GO:1901363 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;ribonucleoprotein complex subunit organization#GO:0071826;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;translation#GO:0006412;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;translational initiation#GO:0006413;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=16|UniProtKB=P01011 P01011 SERPINA3 PTHR11461:SF145 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-1-ANTICHYMOTRYPSIN serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=12783|UniProtKB=P56705 P56705 WNT4 PTHR12027:SF101 WNT RELATED PROTEIN WNT-4 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=24460|UniProtKB=Q7L2H7 Q7L2H7 EIF3M PTHR15350:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cytoplasmic translational initiation#GO:0002183;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular#GO:0005622 HUMAN|HGNC=9812|UniProtKB=P54725 P54725 RAD23A PTHR10621:SF29 UV EXCISION REPAIR PROTEIN RAD23 UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG A proteasome binding#GO:0070628;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;ubiquitin binding#GO:0043130;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 damaged DNA-binding protein#PC00086 HUMAN|HGNC=27312|UniProtKB=Q8IZD0 Q8IZD0 SAMD14 PTHR16154:SF28 NEURABIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 14 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 signal transduction#GO:0007165;neurogenesis#GO:0022008;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;cell projection organization#GO:0030030;developmental process#GO:0032502;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;neuron differentiation#GO:0030182;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 synapse#GO:0045202;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=4868|UniProtKB=O95714 O95714 HERC2 PTHR22870:SF398 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC2-RELATED guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=15931|UniProtKB=O15079 O15079 SNPH PTHR16208:SF1 MICROTUBULE-ASSOCIATED PROTEIN/SYNTAPHILIN SYNTAPHILIN cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 system development#GO:0048731;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;developmental process#GO:0032502;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399 supramolecular complex#GO:0099080;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;mitochondrion#GO:0005739;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 SNARE protein#PC00034 HUMAN|HGNC=24493|UniProtKB=Q9BV44 Q9BV44 THUMPD3 PTHR14911:SF13 THUMP DOMAIN-CONTAINING THUMP DOMAIN-CONTAINING PROTEIN 3 tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA methyltransferase#PC00033 HUMAN|HGNC=811|UniProtKB=O14983 O14983 ATP2A1 PTHR42861:SF24 CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 1 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 bounding membrane of organelle#GO:0098588;sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;sarcoplasmic reticulum membrane#GO:0033017;sarcoplasm#GO:0016528;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=4907|UniProtKB=P31937 P31937 HIBADH PTHR22981:SF7 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED 3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092 HUMAN|HGNC=4390|UniProtKB=P50148 P50148 GNAQ PTHR10218:SF316 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111 positive regulation of lipase activity#GO:0060193;regulation of adenylate cyclase activity#GO:0045761;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;action potential#GO:0001508;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;dopamine receptor signaling pathway#GO:0007212;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of phospholipase C activity#GO:1900274;regulation of membrane potential#GO:0042391;positive regulation of phospholipase activity#GO:0010518;trans-synaptic signaling#GO:0099537;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117 Endothelin signaling pathway#P00019>Gq#P00586;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gqalpha#P05927;Gonadotropin-releasing hormone receptor pathway#P06664>gnaq/11#P06841;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Wnt signaling pathway#P00057>Galpha#P01451;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;PI3 kinase pathway#P00048>Galpha#P01199 HUMAN|HGNC=31813|UniProtKB=Q6ZUM4 Q6ZUM4 ARHGAP27 PTHR23176:SF104 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 27 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;regulation of GTPase activity#GO:0043087 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=3094|UniProtKB=O43781 O43781 DYRK3 PTHR24058:SF35 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;cell cycle process#GO:0022402;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of cell cycle#GO:0045787;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;positive regulation of cell cycle process#GO:0090068;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein-containing complex disassembly#GO:0032984;regulation of cell cycle G2/M phase transition#GO:1902749;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;organelle disassembly#GO:1903008;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;peptidyl-serine modification#GO:0018209;cell cycle G2/M phase transition#GO:0044839 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|Ensembl=ENSG00000285105|UniProtKB=A0A2R8YEG4 A0A2R8YEG4 OR2A1 PTHR26453:SF115 OLFACTORY RECEPTOR G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=11548|UniProtKB=Q5H9L4 Q5H9L4 TAF7L PTHR12228:SF8 TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 7-LIKE molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110;RNA polymerase II general transcription initiation factor activity#GO:0016251 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=10537|UniProtKB=P49591 P49591 SARS1 PTHR11778:SF7 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, CYTOPLASMIC-RELATED catalytic activity, acting on RNA#GO:0140098;tRNA binding#GO:0000049;ligase activity#GO:0016874;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a tRNA#GO:0140101;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 aminoacyl-tRNA synthetase#PC00047 HUMAN|Ensembl=ENSG00000005189|UniProtKB=Q96IC2 Q96IC2 REXO5 PTHR12801:SF82 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 5 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 exoribonuclease#PC00099 HUMAN|HGNC=8872|UniProtKB=P16118 P16118 PFKFB1 PTHR10606:SF15 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578 carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695 carbohydrate phosphatase#PC00066 HUMAN|HGNC=34000|UniProtKB=A6PVC2 A6PVC2 TTLL8 PTHR45870:SF3 TUBULIN MONOGLYCYLASE TTLL3 PROTEIN MONOGLYCYLASE TTLL8 HUMAN|HGNC=19375|UniProtKB=Q9BV35 Q9BV35 SLC25A23 PTHR24089:SF196 SOLUTE CARRIER FAMILY 25 CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN SCAMC-3 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ATP transmembrane transporter activity#GO:0005347;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;ion transmembrane transporter activity#GO:0015075;nucleotide transmembrane transporter activity#GO:0015215;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 mitochondrial carrier protein#PC00158 HUMAN|HGNC=1092|UniProtKB=P58012 P58012 FOXL2 PTHR11829:SF342 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=11054|UniProtKB=Q99884 Q99884 SLC6A7 PTHR11616:SF231 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT PROLINE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=34423|UniProtKB=Q8WTX7 Q8WTX7 CASTOR1 PTHR31131:SF3 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 1 cation binding#GO:0043169;amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;TORC1 signaling#GO:0038202;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=28237|UniProtKB=Q9HBR0 Q9HBR0 SLC38A10 PTHR22950:SF646 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 10-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 amino acid transporter#PC00046 HUMAN|HGNC=1059|UniProtKB=Q13867 Q13867 BLMH PTHR10363:SF2 BLEOMYCIN HYDROLASE BLEOMYCIN HYDROLASE cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=16134|UniProtKB=Q9NUB4 Q9NUB4 C20orf141 PTHR39222:SF1 MCG9903 RIKEN CDNA 1700020A23 GENE HUMAN|HGNC=7237|UniProtKB=Q9Y6F6 Q9Y6F6 IRAG1 PTHR15352:SF2 LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1 INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cGMP-mediated signaling#GO:0019934;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 scaffold/adaptor protein#PC00226 HUMAN|HGNC=21517|UniProtKB=O95620 O95620 DUS4L PTHR11082:SF31 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(20A/20B) SYNTHASE [NAD(P)+]-LIKE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 RNA processing factor#PC00147 HUMAN|HGNC=14053|UniProtKB=Q9NRX2 Q9NRX2 MRPL17 PTHR14413:SF16 RIBOSOMAL PROTEIN L17 39S RIBOSOMAL PROTEIN L17, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=1925|UniProtKB=O14757 O14757 CHEK1 PTHR24343:SF424 SERINE/THREONINE KINASE SERINE/THREONINE-PROTEIN KINASE CHK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=13257|UniProtKB=Q9UMR7 Q9UMR7 CLEC4A PTHR22802:SF426 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER A membrane traffic protein#PC00150 HUMAN|HGNC=3297|UniProtKB=P78344 P78344 EIF4G2 PTHR23253:SF70 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2 translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=13177|UniProtKB=Q9UKS7 Q9UKS7 IKZF2 PTHR24404:SF33 ZINC FINGER PROTEIN ZINC FINGER PROTEIN HELIOS cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3676|UniProtKB=P09038 P09038 FGF2 PTHR11486:SF83 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 2 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 Angiogenesis#P00005>FGF#P00213;FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=42950|UniProtKB=E5RJM6 E5RJM6 ANKRD65 PTHR24166:SF52 ROLLING PEBBLES, ISOFORM B ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 65 HUMAN|HGNC=2956|UniProtKB=P24855 P24855 DNASE1 PTHR11371:SF27 DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE-1 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;endodeoxyribonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;deoxyribonuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;cellular metabolic process#GO:0044237;DNA catabolic process, endonucleolytic#GO:0000737;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11013|UniProtKB=Q9BRI3 Q9BRI3 SLC30A2 PTHR11562:SF51 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER ZINC TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;response to inorganic substance#GO:0010035;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;homeostatic process#GO:0042592;response to metal ion#GO:0010038;cation homeostasis#GO:0055080;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=20885|UniProtKB=Q9NRZ5 Q9NRZ5 AGPAT4 PTHR10983:SF8 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DELTA transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=10479|UniProtKB=P48443 P48443 RXRG PTHR24083:SF100 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR RXR-GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;response to oxygen-containing compound#GO:1901700;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;response to lipid#GO:0033993;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=2597|UniProtKB=Q16678 Q16678 CYP1B1 PTHR24299:SF11 CYTOCHROME P450 FAMILY 1 CYTOCHROME P450 1B1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=16488|UniProtKB=A6NIH7 A6NIH7 UNC119B PTHR12951:SF3 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG B lipid binding#GO:0008289;binding#GO:0005488 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;system development#GO:0048731;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;peptide transport#GO:0015833;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;anatomical structure development#GO:0048856;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=6274|UniProtKB=Q9HB15 Q9HB15 KCNK12 PTHR11003:SF11 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 12 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=23140|UniProtKB=Q8NI99 Q8NI99 ANGPTL6 PTHR19143:SF209 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 6 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=7574|UniProtKB=Q9Y623 Q9Y623 MYH4 PTHR45615:SF49 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-4 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=12362|UniProtKB=Q92574 Q92574 TSC1 PTHR15154:SF2 HAMARTIN HAMARTIN signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of signal transduction#GO:0009966;cellular response to insulin stimulus#GO:0032869;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;TOR signaling#GO:0031929;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell cycle#GO:0007049;negative regulation of signal transduction#GO:0009968;regulation of cell cycle#GO:0051726 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC1#P04495;p53 pathway by glucose deprivation#P04397>TSC1#P04645 HUMAN|HGNC=11134|UniProtKB=Q16533 Q16533 SNAPC1 PTHR15131:SF3 SMALL NUCLEAR RNA ACTIVATING COMPLEX, POLYPEPTIDE 1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 1 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 HUMAN|HGNC=19902|UniProtKB=Q9HB90 Q9HB90 RRAGC PTHR11259:SF6 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN C pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 signal transduction#GO:0007165;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to starvation#GO:0009267;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of autophagy#GO:0010506;cellular metabolic process#GO:0044237;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;nucleus#GO:0005634;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=7962|UniProtKB=P20393 P20393 NR1D1 PTHR24082:SF113 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=10048|UniProtKB=Q93091 Q93091 RNASE6 PTHR11437:SF57 RIBONUCLEASE RIBONUCLEASE K6 ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;defense response to Gram-positive bacterium#GO:0050830;antibacterial humoral response#GO:0019731;defense response to Gram-negative bacterium#GO:0050829;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to bacterium#GO:0009617;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;antimicrobial humoral response#GO:0019730;defense response to other organism#GO:0098542;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=23473|UniProtKB=Q5W0B7 Q5W0B7 TMEM236 PTHR31453:SF2 TRANSMEMBRANE PROTEIN 236 TRANSMEMBRANE PROTEIN 236 HUMAN|HGNC=10725|UniProtKB=Q99985 Q99985 SEMA3C PTHR11036:SF25 SEMAPHORIN SEMAPHORIN-3C receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=24125|UniProtKB=A2A2Y4 A2A2Y4 FRMD3 PTHR23280:SF8 4.1 G PROTEIN FERM DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=21355|UniProtKB=Q5VWP3 Q5VWP3 MLIP PTHR31514:SF1 MUSCULAR LMNA-INTERACTING PROTEIN MLIP MUSCULAR LMNA-INTERACTING PROTEIN molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;envelope#GO:0031975;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;PML body#GO:0016605;plasma membrane#GO:0005886 HUMAN|HGNC=11408|UniProtKB=Q13043 Q13043 STK4 PTHR48015:SF32 SERINE/THREONINE-PROTEIN KINASE TAO SERINE/THREONINE-PROTEIN KINASE 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=31684|UniProtKB=O15391 O15391 YY2 PTHR14003:SF17 TRANSCRIPTIONAL REPRESSOR PROTEIN YY TRANSCRIPTION FACTOR YY2 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=30529|UniProtKB=A8MQ03 A8MQ03 CYSRT1 PTHR37879:SF1 CYSTEINE-RICH TAIL PROTEIN 1 CYSTEINE-RICH TAIL PROTEIN 1 HUMAN|HGNC=10295|UniProtKB=Q92834 Q92834 RPGR PTHR45622:SF53 UBIQUITIN-PROTEIN LIGASE E3A-RELATED X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR ubiquitin-protein ligase#PC00234 HUMAN|HGNC=3774|UniProtKB=Q06828 Q06828 FMOD PTHR45712:SF4 AGAP008170-PA FIBROMODULIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=10522|UniProtKB=Q53FZ2 Q53FZ2 ACSM3 PTHR43605:SF7 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM3, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 HUMAN|HGNC=21095|UniProtKB=Q5TGJ6 Q5TGJ6 HDGFL1 PTHR12550:SF75 HEPATOMA-DERIVED GROWTH FACTOR-RELATED HEPATOMA-DERIVED GROWTH FACTOR-LIKE PROTEIN 1 nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=23057|UniProtKB=Q8WUW1 Q8WUW1 BRK1 PTHR33668:SF1 PROTEIN BRICK1 PROTEIN BRICK1 regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;localization of cell#GO:0051674;regulation of cellular component organization#GO:0051128;cell motility#GO:0048870;cellular component organization#GO:0016043;regulation of actin polymerization or depolymerization#GO:0008064;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036;locomotion#GO:0040011 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=26020|UniProtKB=Q9NX61 Q9NX61 TMEM161A PTHR13624:SF4 RE42071P TRANSMEMBRANE PROTEIN 161A HUMAN|HGNC=21931|UniProtKB=Q6ZU65 Q6ZU65 UBN2 PTHR21669:SF10 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS UBINUCLEIN-2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=30311|UniProtKB=Q8N3Y7 Q8N3Y7 SDR16C5 PTHR24322:SF728 PKSB EPIDERMAL RETINOL DEHYDROGENASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=13524|UniProtKB=P53801 P53801 PTTG1IP PTHR15191:SF2 PROTEIN CBG20567 PITUITARY TUMOR-TRANSFORMING GENE 1 PROTEIN-INTERACTING PROTEIN cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11716|UniProtKB=Q99594 Q99594 TEAD3 PTHR11834:SF7 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED TRANSCRIPTIONAL ENHANCER FACTOR TEF-5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;hippo signaling#GO:0035329;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=16216|UniProtKB=Q9H1P6 Q9H1P6 C20orf85 PTHR31909:SF3 CHROMOSOME 20 ORF85 FAMILY MEMBER RCG40914 HUMAN|HGNC=23493|UniProtKB=Q9HA72 Q9HA72 CALHM2 PTHR32261:SF3 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=13081|UniProtKB=Q9BY12 Q9BY12 SCAPER PTHR31434:SF2 S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM HUMAN|HGNC=30323|UniProtKB=Q8TDB6 Q8TDB6 DTX3L PTHR12622:SF41 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX3L ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=12811|UniProtKB=P51811 P51811 XK PTHR14297:SF8 MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER MEMBRANE TRANSPORT PROTEIN XK HUMAN|HGNC=23150|UniProtKB=Q9UPW8 Q9UPW8 UNC13A PTHR10480:SF1 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG A syntaxin binding#GO:0019905;protein binding#GO:0005515;calmodulin binding#GO:0005516;SNARE binding#GO:0000149;binding#GO:0005488;syntaxin-1 binding#GO:0017075 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;regulated exocytosis#GO:0045055;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;neuromuscular junction development#GO:0007528;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of neurotransmitter levels#GO:0001505;cell junction organization#GO:0034330;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;synaptic transmission, glutamatergic#GO:0035249;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;terminal bouton#GO:0043195;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;presynaptic membrane#GO:0042734;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;neuromuscular junction#GO:0031594;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell cortex#GO:0005938;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;whole membrane#GO:0098805;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=19296|UniProtKB=Q9UF33 Q9UF33 EPHA6 PTHR24416:SF389 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 6 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=12125|UniProtKB=A0A087WT01 A0A087WT01 TRAV27 PTHR19433:SF109 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 27 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=15047|UniProtKB=P0C628 P0C628 OR5AC1 PTHR26452:SF407 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AC1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=18168|UniProtKB=Q9BY07 Q9BY07 SLC4A5 PTHR11453:SF20 ANION EXCHANGE PROTEIN ELECTROGENIC SODIUM BICARBONATE COTRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=30320|UniProtKB=Q7Z5H3 Q7Z5H3 ARHGAP22 PTHR15228:SF22 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 22 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;positive regulation of molecular function#GO:0044093;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of molecular function#GO:0065009;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;regulation of synapse structure or activity#GO:0050803 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cell-substrate junction#GO:0030055;synapse#GO:0045202;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 HUMAN|HGNC=13529|UniProtKB=Q9Y2B0 Q9Y2B0 CNPY2 PTHR13341:SF6 MIR-INTERACTING SAPOSIN-LIKE PROTEIN PROTEIN CANOPY HOMOLOG 2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=25499|UniProtKB=Q9NW75 Q9NW75 GPATCH2 PTHR14195:SF4 G PATCH DOMAIN CONTAINING PROTEIN 2 G PATCH DOMAIN-CONTAINING PROTEIN 2 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;negative regulation of phosphatase activity#GO:0010923;negative regulation of phosphorus metabolic process#GO:0010563;regulation of phosphatase activity#GO:0010921;regulation of dephosphorylation#GO:0035303;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular process#GO:0009987;regulation of catalytic activity#GO:0050790;negative regulation of dephosphorylation#GO:0035305;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of hydrolase activity#GO:0051336;negative regulation of catalytic activity#GO:0043086;negative regulation of cellular process#GO:0048523;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 RNA metabolism protein#PC00031 HUMAN|HGNC=29076|UniProtKB=Q76N32 Q76N32 CEP68 PTHR14514:SF5 PKA ANCHORING PROTEIN CENTROSOMAL PROTEIN OF 68 KDA HUMAN|HGNC=9506|UniProtKB=O60759 O60759 CYTIP PTHR15963:SF1 GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED CYTOHESIN-INTERACTING PROTEIN HUMAN|HGNC=26648|UniProtKB=Q6ZW61 Q6ZW61 BBS12 PTHR46883:SF1 BARDET-BIEDL SYNDROME 12 PROTEIN BARDET-BIEDL SYNDROME 12 PROTEIN HUMAN|HGNC=29614|UniProtKB=O75951 O75951 LYZL6 PTHR11407:SF9 LYSOZYME C LYSOZYME-LIKE PROTEIN 6 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;defense response to Gram-negative bacterium#GO:0050829;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830 HUMAN|HGNC=28573|UniProtKB=Q8N5U1 Q8N5U1 MS4A15 PTHR23320:SF51 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 15 transporter#PC00227 HUMAN|HGNC=16693|UniProtKB=Q16538 Q16538 GPR162 PTHR16518:SF6 G-PROTEIN COUPLED RECEPTOR 153, 162 G-PROTEIN COUPLED RECEPTOR 162-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=379|UniProtKB=Q99996 Q99996 AKAP9 PTHR44981:SF1 PERICENTRIN-LIKE PROTEIN, ISOFORM F A-KINASE ANCHOR PROTEIN 9 HUMAN|HGNC=26931|UniProtKB=O95567 O95567 C22orf31 PTHR15578:SF0 CHROMOSOME 8 C22ORF31 HOMOLOG CHROMOSOME 22 OPEN READING FRAME 31 HUMAN|HGNC=21072|UniProtKB=Q5SRI9 Q5SRI9 MANEA PTHR13572:SF1 ENDO-ALPHA-1,2-MANNOSIDASE GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=5562|UniProtKB=A0A0G2JMI3 A0A0G2JMI3 IGHV1-69-2 PTHR23266:SF317 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-69-2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=18485|UniProtKB=Q9HC36 Q9HC36 MRM3 PTHR43191:SF2 RRNA METHYLTRANSFERASE 3, RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA methyltransferase#PC00033 HUMAN|HGNC=18415|UniProtKB=O75146 O75146 HIP1R PTHR10407:SF10 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN-INTERACTING PROTEIN 1-RELATED PROTEIN cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;clathrin binding#GO:0030276;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;actin binding#GO:0003779 cellular component biogenesis#GO:0044085;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;positive regulation of proteolysis#GO:0045862;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;actin filament-based process#GO:0030029;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;regulation of endocytosis#GO:0030100;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;positive regulation of transport#GO:0051050;programmed cell death#GO:0012501;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein-containing complex assembly#GO:0065003;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of metabolic process#GO:0009893;positive regulation of programmed cell death#GO:0043068;regulation of transport#GO:0051049;supramolecular fiber organization#GO:0097435;cell death#GO:0008219;actin filament organization#GO:0007015;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;vesicle budding from membrane#GO:0006900;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of cell death#GO:0010941;actin cytoskeleton organization#GO:0030036;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell death#GO:0010942 intracellular vesicle#GO:0097708;cortical cytoskeleton#GO:0030863;intracellular membrane-bounded organelle#GO:0043231;cortical actin cytoskeleton#GO:0030864;actin cortical patch#GO:0030479;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 Huntington disease#P00029>Hip-12#P00763 HUMAN|HGNC=1316|UniProtKB=Q9HC35 Q9HC35 EML4 PTHR13720:SF11 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819 HUMAN|HGNC=2894|UniProtKB=Q9UBT3 Q9UBT3 DKK4 PTHR12113:SF10 DICKKOPF3-LIKE 3 DICKKOPF-RELATED PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=15552|UniProtKB=Q8WWZ1 Q8WWZ1 IL1F10 PTHR10078:SF29 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-1 FAMILY MEMBER 10 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to lipopolysaccharide#GO:0071222;gene expression#GO:0010467;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of metabolic process#GO:0009893;response to biotic stimulus#GO:0009607;response to molecule of bacterial origin#GO:0002237;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 interleukin superfamily#PC00128 HUMAN|HGNC=654|UniProtKB=P61204 P61204 ARF3 PTHR11711:SF344 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 HUMAN|HGNC=669|UniProtKB=P08134 P08134 RHOC PTHR24072:SF100 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOC GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 small GTPase#PC00208 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rho#P00860;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>RhoA#P05938;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RhoA#P00740;Ras Pathway#P04393>Rho#P04578;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507 HUMAN|HGNC=4291|UniProtKB=Q14410 Q14410 GK2 PTHR10196:SF46 SUGAR KINASE GLYCEROL KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;triglyceride metabolic process#GO:0006641;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;cellular carbohydrate metabolic process#GO:0044262;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 carbohydrate kinase#PC00065 HUMAN|HGNC=6732|UniProtKB=O95944 O95944 NCR2 PTHR16423:SF7 TREM-LIKE TRANSCRIPT PROTEIN NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|HGNC=11810|UniProtKB=Q13118 Q13118 KLF10 PTHR23235:SF64 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 10 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7833|UniProtKB=P30414 P30414 NKTR PTHR11071:SF257 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NK-TUMOR RECOGNITION PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=7405|UniProtKB=P80297 P80297 MT1X PTHR23299:SF24 METALLOTHIONEIN METALLOTHIONEIN-1X HUMAN|HGNC=2243|UniProtKB=P61923 P61923 COPZ1 PTHR11043:SF2 ZETA-COAT PROTEIN COATOMER SUBUNIT ZETA-1 cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;COPI vesicle coat#GO:0030126;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=21348|UniProtKB=Q71F23 Q71F23 CENPU PTHR32222:SF1 CENTROMERE PROTEIN U CENTROMERE PROTEIN U membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=18823|UniProtKB=Q9P0T7 Q9P0T7 TMEM9 PTHR13064:SF1 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER TRANSMEMBRANE PROTEIN 9 HUMAN|HGNC=20753|UniProtKB=Q96G79 Q96G79 SLC35A4 PTHR10231:SF43 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-SUGAR TRANSPORTER PROTEIN SLC35A4-RELATED bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=6017|UniProtKB=Q01344 Q01344 IL5RA PTHR23036:SF17 CYTOKINE RECEPTOR INTERLEUKIN-5 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=26007|UniProtKB=Q5JUW0 Q5JUW0 KRBOX4 PTHR23232:SF98 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN 4 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=44159|UniProtKB=P0DKB5 P0DKB5 TPBGL PTHR24364:SF16 LP06937P TROPHOBLAST GLYCOPROTEIN-LIKE HUMAN|HGNC=27828|UniProtKB=Q629K1 Q629K1 TRIQK PTHR20583:SF1 TRIPLE QXXK/R MOTIF-CONTAINING PROTEIN TRIPLE QXXK/R MOTIF-CONTAINING PROTEIN HUMAN|HGNC=17879|UniProtKB=Q8N0S6 Q8N0S6 CENPL PTHR31740:SF2 CENTROMERE PROTEIN L CENTROMERE PROTEIN L HUMAN|HGNC=16264|UniProtKB=Q12931 Q12931 TRAP1 PTHR11528:SF44 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN 75 KDA, MITOCHONDRIAL enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;unfolded protein binding#GO:0051082;binding#GO:0005488;kinase binding#GO:0019900 cellular process#GO:0009987;protein folding#GO:0006457 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 Hsp90 family chaperone#PC00028 HUMAN|HGNC=17814|UniProtKB=Q8IX21 Q8IX21 SLF2 PTHR16046:SF10 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR 2 SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 2 HUMAN|HGNC=336|UniProtKB=P30556 P30556 AGTR1 PTHR24228:SF11 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR TYPE-1 ANGIOTENSIN II RECEPTOR hydrolase activity, acting on ester bonds#GO:0016788;signaling receptor activity#GO:0038023;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;G protein-coupled receptor activity#GO:0004930;phosphoric ester hydrolase activity#GO:0042578;transmembrane signaling receptor activity#GO:0004888;lipase activity#GO:0016298;peptide binding#GO:0042277;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;phospholipase C activity#GO:0004629;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;positive regulation of cytosolic calcium ion concentration#GO:0007204;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;inflammatory response#GO:0006954;cellular ion homeostasis#GO:0006873;regulation of biological process#GO:0050789;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cellular divalent inorganic cation homeostasis#GO:0072503;defense response#GO:0006952;metal ion homeostasis#GO:0055065;signaling#GO:0023052 G-protein coupled receptor#PC00021 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>AT1-R#P05924 HUMAN|HGNC=9061|UniProtKB=Q8N3E9 Q8N3E9 PLCD3 PTHR10336:SF33 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-3 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 HUMAN|HGNC=20207|UniProtKB=Q6Y288 Q6Y288 B3GLCT PTHR10811:SF5 FRINGE-RELATED BETA-1,3-GLUCOSYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 HUMAN|HGNC=16986|UniProtKB=Q12907 Q12907 LMAN2 PTHR12223:SF36 VESICULAR MANNOSE-BINDING LECTIN VESICULAR INTEGRAL-MEMBRANE PROTEIN VIP36 carbohydrate binding#GO:0030246;small molecule binding#GO:0036094;binding#GO:0005488 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;Golgi organization#GO:0007030;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 HUMAN|HGNC=14556|UniProtKB=Q6EIG7 Q6EIG7 CLEC6A PTHR22802:SF249 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 6 MEMBER A membrane traffic protein#PC00150 HUMAN|HGNC=16890|UniProtKB=O15194 O15194 CTDSPL PTHR12210:SF43 NUCLEAR LIM INTERACTOR-INTERACTING FACTOR-RELATED CTD SMALL PHOSPHATASE-LIKE PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 HUMAN|HGNC=2909|UniProtKB=Q9NYJ7 Q9NYJ7 DLL3 PTHR24044:SF308 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of Notch signaling pathway#GO:0045746;regulation of Notch signaling pathway#GO:0008593;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;Notch signaling pathway#GO:0007219 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 HUMAN|HGNC=11703|UniProtKB=P51864 P51864 TDGF1P3 PTHR14949:SF43 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 TERATOCARCINOMA-DERIVED GROWTH FACTOR 3-RELATED protein binding#GO:0005515;binding#GO:0005488;receptor serine/threonine kinase binding#GO:0033612;signaling receptor binding#GO:0005102 specification of symmetry#GO:0009799;cellular response to stimulus#GO:0051716;heart development#GO:0007507;signal transduction#GO:0007165;circulatory system development#GO:0072359;enzyme linked receptor protein signaling pathway#GO:0007167;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;determination of bilateral symmetry#GO:0009855;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;determination of left/right symmetry#GO:0007368;pattern specification process#GO:0007389;signaling#GO:0023052 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|Ensembl=ENSG00000285013|UniProtKB=Q9BZC5 Q9BZC5 FKSG35 PTHR26453:SF115 OLFACTORY RECEPTOR G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=13746|UniProtKB=Q9C0B6 Q9C0B6 BRINP2 PTHR15564:SF8 MACPF DOMAIN-CONTAINING PROTEIN BMP/RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 2 HUMAN|HGNC=23752|UniProtKB=Q8IU89 Q8IU89 CERS3 PTHR12560:SF18 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 3 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=27887|UniProtKB=Q32Q52 Q32Q52 C12orf74 PTHR41399:SF1 C12ORF74 ISOFORM 1 CHROMOSOME 12 C12ORF74 HOMOLOG HUMAN|HGNC=26404|UniProtKB=Q4G0N4 Q4G0N4 NADK2 PTHR13158:SF5 FAMILY NOT NAMED NAD KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 metabolic process#GO:0008152 HUMAN|HGNC=10372|UniProtKB=P05386 P05386 RPLP1 PTHR45696:SF29 60S ACIDIC RIBOSOMAL PROTEIN P1 60S ACIDIC RIBOSOMAL PROTEIN P1 structural constituent of ribosome#GO:0003735;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;structural molecule activity#GO:0005198;ribonucleoprotein complex binding#GO:0043021;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational elongation#GO:0006414;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=20673|UniProtKB=P60153 P60153 RNASE9 PTHR11437:SF14 RIBONUCLEASE INACTIVE RIBONUCLEASE-LIKE PROTEIN 9 HUMAN|HGNC=24043|UniProtKB=Q15847 Q15847 ADIRF PTHR39227:SF1 ADIPOGENESIS REGULATORY FACTOR ADIPOGENESIS REGULATORY FACTOR HUMAN|HGNC=7317|UniProtKB=Q96HJ5 Q96HJ5 MS4A3 PTHR23320:SF74 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 3 transporter#PC00227 HUMAN|HGNC=25530|UniProtKB=Q9NVX0 Q9NVX0 HAUS2 PTHR16039:SF1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 2 HUMAN|HGNC=607|UniProtKB=P02654 P02654 APOC1 PTHR16565:SF2 APOLIPOPROTEIN C-I APOLIPOPROTEIN C-I hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;lipid binding#GO:0008289;enzyme inhibitor activity#GO:0004857;organic acid binding#GO:0043177;ion binding#GO:0043167;phospholipase activity#GO:0004620;anion binding#GO:0043168;enzyme regulator activity#GO:0030234 organic hydroxy compound transport#GO:0015850;negative regulation of hydrolase activity#GO:0051346;lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;regulation of lipase activity#GO:0060191;macromolecule localization#GO:0033036;membrane organization#GO:0061024;sterol transport#GO:0015918;transport#GO:0006810;regulation of localization#GO:0032879;lipid catabolic process#GO:0016042;regulation of catalytic activity#GO:0050790;acylglycerol metabolic process#GO:0006639;lipid transport#GO:0006869;neutral lipid metabolic process#GO:0006638;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;negative regulation of multicellular organismal process#GO:0051241;cellular component disassembly#GO:0022411;regulation of transport#GO:0051049;glycerolipid metabolic process#GO:0046486;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;catabolic process#GO:0009056;vesicle organization#GO:0016050;regulation of hydrolase activity#GO:0051336;lipid localization#GO:0010876;receptor-mediated endocytosis#GO:0006898;organic substance catabolic process#GO:1901575;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;plasma lipoprotein particle clearance#GO:0034381;protein-containing complex disassembly#GO:0032984;regulation of multicellular organismal process#GO:0051239;triglyceride metabolic process#GO:0006641;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of transport#GO:0051051;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;cholesterol transport#GO:0030301;negative regulation of catabolic process#GO:0009895;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of lipid metabolic process#GO:0019216;cellular lipid metabolic process#GO:0044255;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;high-density lipoprotein particle#GO:0034364;extracellular region#GO:0005576 apolipoprotein#PC00052 HUMAN|HGNC=40051|UniProtKB=A6NC05 A6NC05 C5orf63 PTHR33558:SF2 GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG GLUTAREDOXIN-LIKE PROTEIN C5ORF63 oxidoreductase#PC00176 HUMAN|HGNC=5956|UniProtKB=Q14623 Q14623 IHH PTHR11889:SF39 HEDGEHOG INDIAN HEDGEHOG PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;smoothened signaling pathway#GO:0007224;macromolecule metabolic process#GO:0043170;developmental process#GO:0032502;gene expression#GO:0010467;cell communication#GO:0007154;cell fate commitment#GO:0045165;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;signaling#GO:0023052;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=14848|UniProtKB=Q8NGN1 Q8NGN1 OR6T1 PTHR24247:SF91 5-HYDROXYTRYPTAMINE RECEPTOR OLFACTORY RECEPTOR 6T1 cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=30098|UniProtKB=Q8N684 Q8N684 CPSF7 PTHR23204:SF2 CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 7 RNA processing factor#PC00147 HUMAN|HGNC=52383|UniProtKB=P0DQD5 P0DQD5 NPY4R2 PTHR24235:SF25 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 4-RELATED neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=7446|UniProtKB=Q9Y4I5 Q9Y4I5 TESMIN PTHR12446:SF22 TESMIN/TSO1-RELATED TESMIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=38842|UniProtKB=B3KU38 B3KU38 IQCJ-SCHIP1 PTHR13103:SF2 SCHWANNOMIN INTERACTING PROTEIN 1 IQCJ-SCHIP1 READTHROUGH TRANSCRIPT PROTEIN regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;hippo signaling#GO:0035329;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;signaling#GO:0023052;positive regulation of biological process#GO:0048518 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=30669|UniProtKB=Q5SQN1 Q5SQN1 SNAP47 PTHR19305:SF1 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 47 syntaxin binding#GO:0019905;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;regulated exocytosis#GO:0045055;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular#GO:0005622;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 SNARE protein#PC00034 HUMAN|HGNC=23733|UniProtKB=A2A3N6 A2A3N6 PIPSL PTHR23086:SF116 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PIP5K1A AND PSMD4-LIKE PROTEIN-RELATED kinase#PC00137 HUMAN|HGNC=32006|UniProtKB=Q5VVP1 Q5VVP1 SPATA31A6 PTHR21859:SF55 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31A1-RELATED HUMAN|HGNC=30738|UniProtKB=B2RN74 B2RN74 OR11H12 PTHR24242:SF201 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H1-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=9406|UniProtKB=Q16513 Q16513 PKN2 PTHR24356:SF322 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE N2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;PDGF signaling pathway#P00047>PKC#P01150 HUMAN|HGNC=19359|UniProtKB=Q5VWW1 Q5VWW1 C1QL3 PTHR22923:SF96 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 3 HUMAN|HGNC=30138|UniProtKB=Q8N131 Q8N131 TMEM123 PTHR11337:SF14 MUCIN/PORIMIN PORIMIN cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=20436|UniProtKB=Q86SH2 Q86SH2 ZAR1 PTHR31054:SF6 ZYGOTE ARREST PROTEIN 1-LIKE ISOFORM X1 ZYGOTE ARREST PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=6798|UniProtKB=P43364 P43364 MAGEA11 PTHR11736:SF146 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 11 scaffold/adaptor protein#PC00226 HUMAN|HGNC=14483|UniProtKB=Q9P0M9 Q9P0M9 MRPL27 PTHR15893:SF0 RIBOSOMAL PROTEIN L27 39S RIBOSOMAL PROTEIN L27, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202 HUMAN|HGNC=17867|UniProtKB=Q9Y639 Q9Y639 NPTN PTHR10075:SF5 BASIGIN RELATED NEUROPLASTIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=22229|UniProtKB=Q8NF64 Q8NF64 ZMIZ2 PTHR10782:SF38 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;ubiquitin-like protein ligase activity#GO:0061659;RNA polymerase II transcription factor binding#GO:0001085;nuclear receptor transcription coactivator activity#GO:0030374;molecular function regulator#GO:0098772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;transcription factor binding#GO:0008134 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 HUMAN|HGNC=4914|UniProtKB=P61086 P61086 UBE2K PTHR24068:SF147 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 K ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490;Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=2211|UniProtKB=P12109 P12109 COL6A1 PTHR24020:SF18 COLLAGEN ALPHA COLLAGEN ALPHA-1(VI) CHAIN extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=20278|UniProtKB=Q8TB37 Q8TB37 NUBPL PTHR42961:SF2 IRON-SULFUR PROTEIN NUBPL IRON-SULFUR PROTEIN NUBPL 4 iron, 4 sulfur cluster binding#GO:0051539;metal cluster binding#GO:0051540;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular process#GO:0009987;metabolic process#GO:0008152 HUMAN|HGNC=19024|UniProtKB=Q96A61 Q96A61 TRIM52 PTHR24103:SF659 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM41-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=7454|UniProtKB=Q9Y216 Q9Y216 MTMR7 PTHR10807:SF35 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 7 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=1322|UniProtKB=Q9NY35 Q9NY35 CLDND1 PTHR14347:SF3 CLAUDIN DOMAIN-CONTAINING PROTEIN 1 CLAUDIN DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=14788|UniProtKB=Q8NGH6 Q8NGH6 OR52L2P PTHR26450:SF353 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52L2-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=11398|UniProtKB=P49842 P49842 STK19 PTHR15243:SF0 SERINE/THREONINE-PROTEIN KINASE 19 SERINE/THREONINE-PROTEIN KINASE 19 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=3290|UniProtKB=O60516 O60516 EIF4EBP3 PTHR12669:SF5 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 3 protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;regulation of translational initiation#GO:0006446;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;translational initiation#GO:0006413;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=24729|UniProtKB=Q96LP6 Q96LP6 C12orf42 PTHR40708:SF1 RIKEN CDNA 1700113H08 GENE RIKEN CDNA 1700113H08 GENE HUMAN|HGNC=21188|UniProtKB=A2A368 A2A368 MAGEB16 PTHR11736:SF145 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B16 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11003|UniProtKB=Q99808 Q99808 SLC29A1 PTHR10332:SF9 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;carbohydrate derivative transport#GO:1901264;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=24972|UniProtKB=Q9Y5Z7 Q9Y5Z7 HCFC2 PTHR46003:SF2 HOST CELL FACTOR HOST CELL FACTOR 2 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of nucleic acid-templated transcription#GO:1903506;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=3622|UniProtKB=O75072 O75072 FKTN PTHR15407:SF28 FUKUTIN-RELATED FUKUTIN HUMAN|Ensembl=ENSG00000230626|UniProtKB=A0A1B0GUL7 A0A1B0GUL7 ENSG00000230626 PTHR47448:SF3 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN PROTEIN KINASE DOMAIN-CONTAINING PROTEIN non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=5649|UniProtKB=P0DP07 P0DP07 IGHV4-31 PTHR23266:SF323 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=26923|UniProtKB=Q969V3 Q969V3 NCLN PTHR31826:SF0 NICALIN NICALIN regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|Ensembl=ENSG00000283267|UniProtKB=A0A1B0GVD1 A0A1B0GVD1 FAM237B PTHR36690:SF1 PROTEIN FAM237A PROTEIN FAM237B HUMAN|HGNC=61|UniProtKB=P33897 P33897 ABCD1 PTHR11384:SF21 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1 transporter activity#GO:0005215;lipid transporter activity#GO:0005319 lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;cellular localization#GO:0051641;macromolecule localization#GO:0033036;organic acid transport#GO:0015849;transport#GO:0006810;very long-chain fatty acid metabolic process#GO:0000038;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;lipid transport#GO:0006869;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;anion transport#GO:0006820;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;lipid oxidation#GO:0034440;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ion transmembrane transport#GO:0034220;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;organic acid transmembrane transport#GO:1903825;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;peroxisome organization#GO:0007031;long-chain fatty acid transport#GO:0015909;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;microbody membrane#GO:0031903;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=4613|UniProtKB=O15499 O15499 GSC2 PTHR46643:SF1 HOMEOBOX PROTEIN GOOSECOID-RELATED HOMEOBOX PROTEIN GOOSECOID-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=12338|UniProtKB=Q9Y210 Q9Y210 TRPC6 PTHR10117:SF7 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 6 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 HUMAN|HGNC=252|UniProtKB=P08319 P08319 ADH4 PTHR43880:SF14 ALCOHOL DEHYDROGENASE ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH4 cation binding#GO:0043169;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 response to organic substance#GO:0010033;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=555|UniProtKB=O43747 O43747 AP1G1 PTHR22780:SF26 ADAPTIN, ALPHA/GAMMA/EPSILON AP-1 COMPLEX SUBUNIT GAMMA-1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network transport vesicle#GO:0030140;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=24415|UniProtKB=Q53S33 Q53S33 BOLA3 PTHR46188:SF1 BOLA-LIKE PROTEIN 3 BOLA-LIKE PROTEIN 3 HUMAN|HGNC=33824|UniProtKB=P0DPF6 P0DPF6 CDRT15P3 PTHR16471:SF2 CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN-LIKE PROTEIN SUBFAMILY NOT NAMED HUMAN|HGNC=14988|UniProtKB=Q9H488 Q9H488 POFUT1 PTHR21420:SF3 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neurotic#P01115 HUMAN|HGNC=1318|UniProtKB=P01024 P01024 C3 PTHR11412:SF81 MACROGLOBULIN / COMPLEMENT COMPLEMENT C3 protease inhibitor#PC00191 HUMAN|HGNC=9109|UniProtKB=P20382 P20382 PMCH PTHR12091:SF0 MELANIN-CONCENTRATING HORMONE PRO-MCH-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 peptide hormone#PC00179 HUMAN|HGNC=10910|UniProtKB=Q13621 Q13621 SLC12A1 PTHR11827:SF93 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;sodium:chloride symporter activity#GO:0015378;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;chloride transport#GO:0006821;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;regulation of cellular component size#GO:0032535;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725 secondary carrier transporter#PC00258 HUMAN|HGNC=6641|UniProtKB=P25800 P25800 LMO1 PTHR45787:SF2 LD11652P RHOMBOTIN-1 HUMAN|HGNC=20162|UniProtKB=Q9H972 Q9H972 C14orf93 PTHR14375:SF2 UNCHARACTERIZED SIMILAR TO RIKEN CDNA 4931414P19 HUMAN|HGNC=21296|UniProtKB=Q9H6S3 Q9H6S3 EPS8L2 PTHR12287:SF20 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8-LIKE PROTEIN 2 Rho guanyl-nucleotide exchange factor activity#GO:0005089;cytoskeletal protein binding#GO:0008092;Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;actin binding#GO:0003779;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cell projection organization#GO:0030030;positive regulation of cell projection organization#GO:0031346;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;regulation of cellular component organization#GO:0051128;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;positive regulation of cellular component biogenesis#GO:0044089;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;regulation of Rho protein signal transduction#GO:0035023;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection assembly#GO:0030031;Rho protein signal transduction#GO:0007266;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of cell projection assembly#GO:0060491;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;plasma membrane bounded cell projection assembly#GO:0120031;regulation of Ras protein signal transduction#GO:0046578 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=214|UniProtKB=Q9H2U9 Q9H2U9 ADAM7 PTHR11905:SF21 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 7 hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=3795|UniProtKB=P41439 P41439 FOLR3 PTHR10517:SF17 FOLATE RECEPTOR FOLATE RECEPTOR GAMMA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell recognition#GO:0008037;plasma membrane fusion#GO:0045026;fertilization#GO:0009566;membrane organization#GO:0061024;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;biological adhesion#GO:0022610;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;multi-organism process#GO:0051704;cell-cell recognition#GO:0009988;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;membrane fusion#GO:0061025;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;multi-organism reproductive process#GO:0044703 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;anchored component of plasma membrane#GO:0046658;intrinsic component of membrane#GO:0031224;intrinsic component of plasma membrane#GO:0031226;anchored component of membrane#GO:0031225;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=15986|UniProtKB=Q9H9Z2 Q9H9Z2 LIN28A PTHR46109:SF2 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG A RNA metabolism protein#PC00031 HUMAN|HGNC=3679|UniProtKB=Q9HCT0 Q9HCT0 FGF22 PTHR11486:SF41 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 22 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=19735|UniProtKB=Q7L775 Q7L775 EPM2AIP1 PTHR45913:SF11 EPM2A-INTERACTING PROTEIN 1 EPM2A-INTERACTING PROTEIN 1 HUMAN|HGNC=1554|UniProtKB=O00257 O00257 CBX4 PTHR46727:SF1 E3 SUMO-PROTEIN LIGASE CBX4 E3 SUMO-PROTEIN LIGASE CBX4 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=12608|UniProtKB=Q14694 Q14694 USP10 PTHR24006:SF687 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=6546|UniProtKB=Q14746 Q14746 COG2 PTHR12961:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=14856|UniProtKB=Q9H342 Q9H342 OR51J1 PTHR26450:SF81 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51J1 transmembrane signal receptor#PC00197 HUMAN|HGNC=202|UniProtKB=O75077 O75077 ADAM23 PTHR11905:SF13 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 23 presynapse#GO:0098793;synapse#GO:0045202;cell junction#GO:0030054;integral component of synaptic membrane#GO:0099699;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;synaptic membrane#GO:0097060;presynaptic membrane#GO:0042734;intrinsic component of membrane#GO:0031224;intrinsic component of synaptic membrane#GO:0099240;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=43943|UniProtKB=E9PB15 E9PB15 PTGES3L PTHR22932:SF4 TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE PROTEIN PTGES3L-RELATED protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488;chaperone binding#GO:0051087;Hsp90 protein binding#GO:0051879 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein folding#GO:0006457;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=29165|UniProtKB=Q9Y2K2 Q9Y2K2 SIK3 PTHR24346:SF42 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE/THREONINE-PROTEIN KINASE SIK3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=26112|UniProtKB=Q7L3V2 Q7L3V2 RTL10 PTHR15503:SF4 LDOC1 RELATED PROTEIN BOP intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6803|UniProtKB=P43359 P43359 MAGEA5 PTHR11736:SF48 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 4-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=30329|UniProtKB=P78345 P78345 RPP38 PTHR46948:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P38 RIBONUCLEASE P PROTEIN SUBUNIT P38 HUMAN|HGNC=1266|UniProtKB=Q9Y426 Q9Y426 C2CD2 PTHR21119:SF7 UNCHARACTERIZED C2 DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=14198|UniProtKB=Q9BQ52 Q9BQ52 ELAC2 PTHR12553:SF49 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mitochondrial gene expression#GO:0140053;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 HUMAN|HGNC=8812|UniProtKB=Q16654 Q16654 PDK4 PTHR11947:SF22 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 4, MITOCHONDRIAL transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;negative regulation of metabolic process#GO:0009892;regulation of catalytic activity#GO:0050790;chemical homeostasis#GO:0048878;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=7861|UniProtKB=P40261 P40261 NNMT PTHR10867:SF32 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 HUMAN|HGNC=9410|UniProtKB=Q04759 Q04759 PRKCQ PTHR24356:SF181 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C THETA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>PKCtheta#P07140;EGF receptor signaling pathway#P00018>PKC#P00565;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Apoptosis signaling pathway#P00006>PKCs#P00318;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;T cell activation#P00053>PKC-theta#P01318;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Gonadotropin-releasing hormone receptor pathway#P06664>PKCe/theta#P06798;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 HUMAN|HGNC=17909|UniProtKB=Q9BY84 Q9BY84 DUSP16 PTHR10159:SF343 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 16 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=10432|UniProtKB=P51812 P51812 RPS6KA3 PTHR24351:SF58 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 Ras Pathway#P04393>p90RSK#P04541;Interleukin signaling pathway#P00036>p90RSK#P00964;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;CCKR signaling map#P06959>RSK1/2#P07153;PDGF signaling pathway#P00047>p90RSK#P01142 HUMAN|HGNC=14340|UniProtKB=Q9UBQ0 Q9UBQ0 VPS29 PTHR11124:SF12 VACUOLAR SORTING PROTEIN VPS29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 29 vesicle coat protein#PC00235 HUMAN|HGNC=19702|UniProtKB=Q96HA1 Q96HA1 POM121 PTHR23193:SF43 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR ENVELOPE PORE MEMBRANE PROTEIN POM 121 signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=1754|UniProtKB=P55291 P55291 CDH15 PTHR24027:SF300 CADHERIN-23 CADHERIN-15 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=12508|UniProtKB=Q9UMX0 Q9UMX0 UBQLN1 PTHR10677:SF16 UBIQUILIN UBIQUILIN-1 protein binding#GO:0005515;binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=6158|UniProtKB=P16144 P16144 ITGB4 PTHR10082:SF42 INTEGRIN BETA SUBUNIT INTEGRIN BETA-4 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;biological adhesion#GO:0022610;localization of cell#GO:0051674;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052 membrane protein complex#GO:0098796;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;focal adhesion#GO:0005925;integral component of plasma membrane#GO:0005887;cell-substrate junction#GO:0030055;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 HUMAN|HGNC=11793|UniProtKB=P52888 P52888 THOP1 PTHR11804:SF50 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED THIMET OLIGOPEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 metalloprotease#PC00153 HUMAN|HGNC=16394|UniProtKB=Q9BX69 Q9BX69 CARD6 PTHR22797:SF36 CARD6/NUCLEOLAR PROTEIN 3 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 6 HUMAN|HGNC=25330|UniProtKB=Q9P2B4 Q9P2B4 CTTNBP2NL PTHR23166:SF9 FILAMIN/GPBP-INTERACTING PROTEIN CTTNBP2 N-TERMINAL-LIKE PROTEIN HUMAN|HGNC=5175|UniProtKB=P52594 P52594 AGFG1 PTHR46134:SF1 DRONGO, ISOFORM F ARF-GAP DOMAIN AND FG REPEAT-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=25699|UniProtKB=Q9HA65 Q9HA65 TBC1D17 PTHR22957:SF360 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 17 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=6972|UniProtKB=P21741 P21741 MDK PTHR13850:SF2 PLEIOTROPHIN FAMILY MEMBER MIDKINE binding#GO:0005488;receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 growth factor#PC00112 HUMAN|HGNC=4091|UniProtKB=P28476 P28476 GABRR2 PTHR18945:SF197 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT RHO-2 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;system process#GO:0003008;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=14865|UniProtKB=Q8N693 Q8N693 ESX1 PTHR24329:SF545 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ESX1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=3964|UniProtKB=P01225 P01225 FSHB PTHR11515:SF17 GLYCOPROTEIN HORMONE BETA CHAIN FOLLITROPIN SUBUNIT BETA receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576;intracellular#GO:0005622 peptide hormone#PC00179 Gonadotropin-releasing hormone receptor pathway#P06664>3' FSHbeta#G06900;Gonadotropin-releasing hormone receptor pathway#P06664>FSHbeta#G06678;Gonadotropin-releasing hormone receptor pathway#P06664>5' FSHbeta#G06904;Gonadotropin-releasing hormone receptor pathway#P06664>FSHbeta#P06809 HUMAN|HGNC=23622|UniProtKB=Q8TDT2 Q8TDT2 GPR152 PTHR11334:SF1 MAS-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 152-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=18908|UniProtKB=Q9BYR4 Q9BYR4 KRTAP4-3 PTHR23262:SF225 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-3 HUMAN|HGNC=24587|UniProtKB=Q9BYI3 Q9BYI3 FAM126A PTHR31220:SF4 HYCCIN RELATED HYCCIN protein localization to plasma membrane#GO:0072659;lipid metabolic process#GO:0006629;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;protein localization#GO:0008104;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;localization#GO:0051179;protein localization to cell periphery#GO:1990778;glycerolipid metabolic process#GO:0046486;cellular macromolecule localization#GO:0070727;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=28413|UniProtKB=Q96H35 Q96H35 RBM18 PTHR21245:SF2 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 18-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA metabolism protein#PC00031 HUMAN|HGNC=17074|UniProtKB=Q6SZW1 Q6SZW1 SARM1 PTHR22998:SF1 SARM1 NAD(+) HYDROLASE SARM1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9789|UniProtKB=O14966 O14966 RAB29 PTHR24073:SF315 DRAB5-RELATED RAS-RELATED PROTEIN RAB-7L1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;pigmentation#GO:0043473;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;melanosome organization#GO:0032438;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;mitochondrion#GO:0005739;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=6936|UniProtKB=Q96RQ3 Q96RQ3 MCCC1 PTHR18866:SF33 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824 ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 HUMAN|HGNC=25259|UniProtKB=Q8N8A2 Q8N8A2 ANKRD44 PTHR24123:SF82 ANKYRIN REPEAT-CONTAINING SERINE/THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY ANKYRIN REPEAT SUBUNIT B scaffold/adaptor protein#PC00226 HUMAN|HGNC=25486|UniProtKB=Q6NSI4 Q6NSI4 RADX PTHR14944:SF2 RPA-RELATED PROTEIN RADX RPA-RELATED PROTEIN RADX nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;regulation of DNA repair#GO:0006282;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;replication fork#GO:0005657 HUMAN|HGNC=29847|UniProtKB=O14513 O14513 NCKAP5 PTHR21740:SF0 NCK-ASSOCIATED PROTEIN 5 NCK-ASSOCIATED PROTEIN 5 cellular protein complex disassembly#GO:0043624;protein-containing complex disassembly#GO:0032984;microtubule depolymerization#GO:0007019;microtubule cytoskeleton organization#GO:0000226;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;cytoskeleton organization#GO:0007010;protein-containing complex subunit organization#GO:0043933 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;intracellular organelle#GO:0043229;microtubule#GO:0005874 HUMAN|HGNC=470|UniProtKB=Q01432 Q01432 AMPD3 PTHR11359:SF2 AMP DEAMINASE AMP DEAMINASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;IMP metabolic process#GO:0046040;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;AMP metabolic process#GO:0046033;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleoside monophosphate metabolic process#GO:0009161;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 deaminase#PC00088 Purine metabolism#P02769>5'-AMP Deaminase#P03117 HUMAN|HGNC=11368|UniProtKB=P42226 P42226 STAT6 PTHR11801:SF48 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;defense response#GO:0006952;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;response to peptide hormone#GO:0043434;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;regulation of transcription, DNA-templated#GO:0006355;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;organic cyclic compound biosynthetic process#GO:1901362;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>STAT#P01173;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>STAT#P00832;JAK/STAT signaling pathway#P00038>STAT#P01027;Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561 HUMAN|HGNC=16266|UniProtKB=Q9BZV2 Q9BZV2 SLC19A3 PTHR10686:SF37 FOLATE TRANSPORTER THIAMINE TRANSPORTER 2 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=1951|UniProtKB=P08172 P08172 CHRM2 PTHR24247:SF207 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR M2 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;organic cyclic compound binding#GO:0097159;acetylcholine receptor activity#GO:0015464;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;acetylcholine binding#GO:0042166;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of muscle contraction#GO:0006937;negative regulation of intracellular signal transduction#GO:1902532;regulation of cyclase activity#GO:0031279;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of system process#GO:0044057;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;negative regulation of response to stimulus#GO:0048585;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;smooth muscle contraction#GO:0006939;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;negative regulation of catalytic activity#GO:0043086;cAMP-mediated signaling#GO:0019933;muscle system process#GO:0003012;cyclic-nucleotide-mediated signaling#GO:0019935;muscle contraction#GO:0006936;negative regulation of molecular function#GO:0044092 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alzheimer disease-amyloid secretase pathway#P00003>Muscarinic acetylcholine receptors#P00083;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>mAChR2/4#P01077;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=32955|UniProtKB=Q6NSI1 Q6NSI1 ANKRD26P1 PTHR24118:SF53 POTE ANKYRIN DOMAIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 26-LIKE PROTEIN-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=12826|UniProtKB=O43592 O43592 XPOT PTHR15952:SF12 EXPORTIN-T/LOS1 EXPORTIN-T tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;Ras GTPase binding#GO:0017016;binding#GO:0005488;organic cyclic compound binding#GO:0097159;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;small GTPase binding#GO:0031267 cellular localization#GO:0051641;establishment of RNA localization#GO:0051236;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;peptide transport#GO:0015833;ribonucleoprotein complex localization#GO:0071166;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;RNA transport#GO:0050658;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;nuclear transport#GO:0051169;protein-containing complex localization#GO:0031503 membrane-enclosed lumen#GO:0031974;envelope#GO:0031975;nuclear pore#GO:0005643;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;nuclear periphery#GO:0034399;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;plasma membrane#GO:0005886 RNA metabolism protein#PC00031 HUMAN|HGNC=15500|UniProtKB=Q96PV6 Q96PV6 LENG8 PTHR12436:SF4 80 KDA MCM3-ASSOCIATED PROTEIN LEUKOCYTE RECEPTOR CLUSTER MEMBER 8 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17301|UniProtKB=Q9UHG2 Q9UHG2 PCSK1N PTHR15531:SF0 PROSAAS PROSAAS peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase inhibitor activity#GO:0004866;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=29046|UniProtKB=Q9NVF7 Q9NVF7 FBXO28 PTHR13252:SF9 F-BOX ONLY PROTEIN 28 F-BOX ONLY PROTEIN 28 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=23574|UniProtKB=Q504Y3 Q504Y3 ZCWPW2 PTHR15999:SF5 UNCHARACTERIZED ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 2 HUMAN|HGNC=5471|UniProtKB=P18065 P18065 IGFBP2 PTHR11551:SF5 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 2 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=28208|UniProtKB=Q5SV97 Q5SV97 PERM1 PTHR47282:SF1 PGC-1 AND ERR-INDUCED REGULATOR IN MUSCLE PROTEIN 1 PGC-1 AND ERR-INDUCED REGULATOR IN MUSCLE PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=27232|UniProtKB=Q96NL8 Q96NL8 C8orf37 PTHR33958:SF1 PROTEIN C8ORF37 PROTEIN C8ORF37 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=7227|UniProtKB=O14807 O14807 MRAS PTHR24070:SF268 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN M-RAS GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Ras#P00552 HUMAN|HGNC=16491|UniProtKB=Q9HB75 Q9HB75 PIDD1 PTHR45752:SF44 LEUCINE-RICH REPEAT-CONTAINING P53-INDUCED DEATH DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;signal transduction#GO:0007165;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;signaling#GO:0023052;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of cellular protein metabolic process#GO:0032270;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;positive regulation of cell death#GO:0010942;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=7638|UniProtKB=Q9ULW6 Q9ULW6 NAP1L2 PTHR11875:SF36 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 2-RELATED protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;organelle organization#GO:0006996;chromosome organization#GO:0051276;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=33818|UniProtKB=Q6J272 Q6J272 FAM166A PTHR47299:SF1 PROTEIN FAM166A PROTEIN FAM166A HUMAN|HGNC=25032|UniProtKB=Q8WW52 Q8WW52 FAM151A PTHR21184:SF4 MENORIN (DENDRITIC BRANCHING PROTEIN) PROTEIN FAM151A HUMAN|HGNC=30960|UniProtKB=Q7Z7L7 Q7Z7L7 ZER1 PTHR12904:SF23 FAMILY NOT NAMED PROTEIN ZER-1 HOMOLOG protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=13078|UniProtKB=Q2VY69 Q2VY69 ZNF284 PTHR24388:SF36 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 221-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=32462|UniProtKB=A6NNF4 A6NNF4 ZNF726 PTHR24377:SF912 IP01015P-RELATED ZINC FINGER PROTEIN 254-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=7623|UniProtKB=Q9UL68 Q9UL68 MYT1L PTHR10816:SF11 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=11057|UniProtKB=P30825 P30825 SLC7A1 PTHR43243:SF28 INNER MEMBRANE TRANSPORTER YGJI-RELATED HIGH AFFINITY CATIONIC AMINO ACID TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;L-lysine transmembrane transporter activity#GO:0015189;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;basic amino acid transmembrane transporter activity#GO:0015174;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;basic amino acid transmembrane transport#GO:1990822;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;basic amino acid transport#GO:0015802;L-alpha-amino acid transmembrane transport#GO:1902475;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046 HUMAN|HGNC=19712|UniProtKB=A7MBM2 A7MBM2 DISP2 PTHR45951:SF2 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED HOMOLOG 2 HUMAN|HGNC=30279|UniProtKB=Q86X27 Q86X27 RALGPS2 PTHR23113:SF353 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS2 guanyl-nucleotide exchange factor#PC00113 PDGF signaling pathway#P00047>SOS#P01159;EGF receptor signaling pathway#P00018>SOS#P00558 HUMAN|HGNC=7801|UniProtKB=Q96HA7 Q96HA7 TONSL PTHR46358:SF1 TONSOKU-LIKE PROTEIN TONSOKU-LIKE PROTEIN HUMAN|HGNC=13229|UniProtKB=Q96KV6 Q96KV6 BTN2A3P PTHR24100:SF110 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 2 MEMBER A3-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=11748|UniProtKB=Q12800 Q12800 TFCP2 PTHR11037:SF11 TRANSCRIPTION FACTOR CP2 ALPHA-GLOBIN TRANSCRIPTION FACTOR CP2 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=7695|UniProtKB=O75438 O75438 NDUFB1 PTHR15222:SF4 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 1 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 dehydrogenase#PC00092 HUMAN|HGNC=14534|UniProtKB=Q08648 Q08648 SPAG11B PTHR14081:SF1 SPERM-ASSOCIATED ANTIGEN 11A-RELATED-RELATED SPERM-ASSOCIATED ANTIGEN 11A-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 HUMAN|HGNC=14554|UniProtKB=Q8WXI8 Q8WXI8 CLEC4D PTHR22802:SF11 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER D membrane traffic protein#PC00150 HUMAN|HGNC=26278|UniProtKB=Q96AB3 Q96AB3 ISOC2 PTHR14119:SF3 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2 hydrolase#PC00121 HUMAN|HGNC=26888|UniProtKB=Q8N2R8 Q8N2R8 FAM43A PTHR11232:SF36 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PROTEIN FAM43A scaffold/adaptor protein#PC00226 HUMAN|HGNC=9549|UniProtKB=P17980 P17980 PSMC3 PTHR23073:SF90 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6A positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription, initiation#GO:2000142;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of transcription initiation from RNA polymerase II promoter#GO:0060260;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;positive regulation of transcription initiation from RNA polymerase II promoter#GO:0060261;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of protein-containing complex assembly#GO:0043254;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of RNA polymerase II transcription preinitiation complex assembly#GO:0045899;positive regulation of cellular component biogenesis#GO:0044089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of protein-containing complex assembly#GO:0031334;regulation of primary metabolic process#GO:0080090;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of DNA-templated transcription, initiation#GO:2000144;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;intracellular#GO:0005622;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;proteasome regulatory particle, base subcomplex#GO:0008540 protease#PC00190 HUMAN|HGNC=4008|UniProtKB=Q9BTY2 Q9BTY2 FUCA2 PTHR10030:SF45 ALPHA-L-FUCOSIDASE PLASMA ALPHA-L-FUCOSIDASE glycosidase#PC00110 HUMAN|HGNC=18190|UniProtKB=Q5T619 Q5T619 ZNF648 PTHR24388:SF50 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 281-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1907|UniProtKB=O95992 O95992 CH25H PTHR11863:SF213 STEROL DESATURASE CHOLESTEROL 25-HYDROXYLASE steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;secondary alcohol metabolic process#GO:1902652;steroid biosynthetic process#GO:0006694;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 oxidase#PC00175 HUMAN|HGNC=3252|UniProtKB=O14602 O14602 EIF1AY PTHR21668:SF17 EIF-1A EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, Y-CHROMOSOMAL translation initiation factor#PC00224 HUMAN|HGNC=17546|UniProtKB=Q8WYK2 Q8WYK2 JDP2 PTHR23351:SF10 FOS TRANSCRIPTION FACTOR-RELATED JUN DIMERIZATION PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302 HUMAN|HGNC=37210|UniProtKB=B7Z1M9 B7Z1M9 C2CD4D PTHR46291:SF1 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4D HUMAN|HGNC=5341|UniProtKB=P21815 P21815 IBSP PTHR10345:SF0 BONE SIALOPROTEIN 2 BONE SIALOPROTEIN 2 biomineralization#GO:0110148;ossification#GO:0001503;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;tissue development#GO:0009888;bone mineralization#GO:0030282;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;biomineral tissue development#GO:0031214 extracellular matrix structural protein#PC00103 HUMAN|HGNC=21904|UniProtKB=Q86XI2 Q86XI2 NCAPG2 PTHR16199:SF4 CONDENSIN-2 COMPLEX SUBUNIT G2 CONDENSIN-2 COMPLEX SUBUNIT G2 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=13535|UniProtKB=O60423 O60423 ATP8B3 PTHR24092:SF78 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IK pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=17412|UniProtKB=Q9UBD9 Q9UBD9 CLCF1 PTHR21353:SF7 FAMILY NOT NAMED CARDIOTROPHIN-LIKE CYTOKINE FACTOR 1 HUMAN|HGNC=8919|UniProtKB=O43189 O43189 PHF1 PTHR12628:SF11 POLYCOMB-LIKE TRANSCRIPTION FACTOR PHD FINGER PROTEIN 1 nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=5391|UniProtKB=P35475 P35475 IDUA PTHR12631:SF8 ALPHA-L-IDURONIDASE ALPHA-L-IDURONIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110 HUMAN|HGNC=9520|UniProtKB=Q16557 Q16557 PSG3 PTHR44427:SF12 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 3 HUMAN|HGNC=24770|UniProtKB=Q0D2K2 Q0D2K2 KLHL30 PTHR24412:SF398 KELCH PROTEIN KELCH-LIKE PROTEIN 30 scaffold/adaptor protein#PC00226 HUMAN|HGNC=7961|UniProtKB=Q15466 Q15466 NR0B2 PTHR24081:SF0 NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B MEMBER 2 molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;organic substance metabolic process#GO:0071704;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of molecular function#GO:0044092;negative regulation of DNA-binding transcription factor activity#GO:0043433 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=27113|UniProtKB=W5XKT8 W5XKT8 SPACA6 PTHR37366:SF1 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 6 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 6 HUMAN|HGNC=23316|UniProtKB=O14756 O14756 HSD17B6 PTHR43313:SF4 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 6 dehydrogenase#PC00092 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 HUMAN|HGNC=20984|UniProtKB=Q6QNY1 Q6QNY1 BLOC1S2 PTHR46479:SF1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 HUMAN|HGNC=18210|UniProtKB=Q96PD6 Q96PD6 MOGAT1 PTHR12317:SF26 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=30180|UniProtKB=Q8WUB2 Q8WUB2 FAM216A PTHR16476:SF1 FAMILY NOT NAMED PROTEIN FAM216A HUMAN|HGNC=8062|UniProtKB=P49790 P49790 NUP153 PTHR23193:SF23 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP153 signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=1975|UniProtKB=P58304 P58304 VSX2 PTHR46892:SF1 VISUAL SYSTEM HOMEOBOX 2 VISUAL SYSTEM HOMEOBOX 2 sequence-specific DNA binding#GO:0043565;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;retina development in camera-type eye#GO:0060041;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;visual system development#GO:0150063;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;eye development#GO:0001654;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;camera-type eye development#GO:0043010;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=11554|UniProtKB=P37802 P37802 TAGLN2 PTHR18959:SF41 CALPONIN/TRANSGELIN TRANSGELIN-2 non-motor actin binding protein#PC00165 HUMAN|HGNC=24956|UniProtKB=Q9NRN5 Q9NRN5 OLFML3 PTHR23192:SF8 OLFACTOMEDIN-RELATED OLFACTOMEDIN-LIKE PROTEIN 3 structural protein#PC00211 HUMAN|HGNC=25618|UniProtKB=Q8IY42 Q8IY42 C4orf19 PTHR16106:SF3 CHROMOSOME 4 OPEN READING FRAME 19 CHROMOSOME 4 OPEN READING FRAME 19 HUMAN|HGNC=25503|UniProtKB=Q9NW64 Q9NW64 RBM22 PTHR14089:SF18 PRE-MRNA-SPLICING FACTOR RBM22 PRE-MRNA-SPLICING FACTOR RBM22 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;snRNA binding#GO:0017069;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Lsm2-8 complex#GO:0120115;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=20321|UniProtKB=Q5TAP6 Q5TAP6 UTP14C PTHR14150:SF16 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 HOMOLOG C membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=24355|UniProtKB=Q8NC01 Q8NC01 CLEC1A PTHR46490:SF1 C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A-RELATED C-TYPE LECTIN DOMAIN FAMILY 1 MEMBER A HUMAN|HGNC=5919|UniProtKB=A0A075B6K6 A0A075B6K6 IGLV4-3 PTHR23267:SF462 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 4-3 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=33898|UniProtKB=Q3LI54 Q3LI54 KRTAP19-8 PTHR38140:SF3 KERATIN-ASSOCIATED PROTEIN 19-3-RELATED KERATIN-ASSOCIATED PROTEIN 19-8 HUMAN|HGNC=31106|UniProtKB=Q8TBZ8 Q8TBZ8 ZNF564 PTHR24404:SF10 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 564 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=24862|UniProtKB=Q13724 Q13724 MOGS PTHR10412:SF11 MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 glucosidase#PC00108 HUMAN|HGNC=15528|UniProtKB=Q99675 Q99675 CGRRF1 PTHR15379:SF2 CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1 CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;growth#GO:0040007;cellular component organization#GO:0016043;regulation of growth#GO:0040008;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;cell growth#GO:0016049;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558 HUMAN|HGNC=13499|UniProtKB=Q3ZCT1 Q3ZCT1 ZNF260 PTHR24377:SF778 IP01015P-RELATED ZINC FINGER PROTEIN 260 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25335|UniProtKB=Q8ND24 Q8ND24 RNF214 PTHR15727:SF3 RING FINGER PROTEIN 214 RING FINGER PROTEIN 214 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 HUMAN|HGNC=1034|UniProtKB=Q14457 Q14457 BECN1 PTHR12768:SF6 BECLIN 1 BECLIN-1 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;protein targeting to vacuole#GO:0006623;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;late endosome to vacuole transport#GO:0045324;response to extracellular stimulus#GO:0009991;establishment of protein localization#GO:0045184;vacuole organization#GO:0007033;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;establishment of protein localization to vacuole#GO:0072666;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;protein maturation#GO:0051604;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;protein transport#GO:0015031;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;autophagy#GO:0006914;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein processing#GO:0016485;process utilizing autophagic mechanism#GO:0061919;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular response to starvation#GO:0009267;vacuolar protein processing#GO:0006624;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular response to stimulus#GO:0051716;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;establishment of protein localization to organelle#GO:0072594;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle assembly#GO:0070925;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cellular response to nutrient levels#GO:0031669;organelle organization#GO:0006996;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;intracellular#GO:0005622;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;phosphatidylinositol 3-kinase complex, class III#GO:0035032;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 protease inhibitor#PC00191 HUMAN|HGNC=4581|UniProtKB=Q13003 Q13003 GRIK3 PTHR18966:SF174 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 3 amino acid binding#GO:0016597;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;molecular transducer activity#GO:0060089;ion binding#GO:0043167;anion binding#GO:0043168;sodium channel activity#GO:0005272;glutamate binding#GO:0016595;signaling receptor activity#GO:0038023;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;monovalent inorganic cation transmembrane transporter activity#GO:0015077;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;transporter activity#GO:0005215;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA#P01026;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Huntington disease#P00029>Kainate receptor#P00796;Ionotropic glutamate receptor pathway#P00037>KA3#P01002 HUMAN|HGNC=27000|UniProtKB=Q8IVT2 Q8IVT2 MISP PTHR18839:SF3 MITOTIC INTERACTOR AND SUBSTRATE OF PLK1 MISP FAMILY MEMBER MITOTIC INTERACTOR AND SUBSTRATE OF PLK1 HUMAN|HGNC=18040|UniProtKB=Q8NFD5 Q8NFD5 ARID1B PTHR12656:SF11 BRG-1 ASSOCIATED FACTOR 250 BAF250 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1B nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=16400|UniProtKB=Q96P20 Q96P20 NLRP3 PTHR45690:SF15 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 3 HUMAN|HGNC=5227|UniProtKB=Q9ULV5 Q9ULV5 HSF4 PTHR10015:SF213 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN 4 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=15818|UniProtKB=Q9H0Z9 Q9H0Z9 RBM38 PTHR48024:SF28 GEO13361P1-RELATED RNA-BINDING PROTEIN 38 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26249|UniProtKB=Q56UN5 Q56UN5 MAP3K19 PTHR48011:SF4 CCR4-NOT TRANSCRIPTIONAL COMPLEX SUBUNIT CAF120-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19 EGF receptor signaling pathway#P00018>MEKK1-5#P00553 HUMAN|Ensembl=ENSG00000272899|UniProtKB=A0A1B0GUX0 A0A1B0GUX0 ATP6V1FNB PTHR35826:SF2 PROTEIN ATP6V1FNB-LIKE PROTEIN ATP6V1FNB HUMAN|HGNC=31452|UniProtKB=Q8IV03 Q8IV03 LURAP1L PTHR33767:SF1 FAMILY NOT NAMED LEUCINE RICH ADAPTOR PROTEIN 1-LIKE HUMAN|HGNC=1810|UniProtKB=Q9Y6F7 Q9Y6F7 CDY2B PTHR43684:SF6 FAMILY NOT NAMED TESTIS-SPECIFIC CHROMODOMAIN PROTEIN Y 1-RELATED transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=3334|UniProtKB=P54851 P54851 EMP2 PTHR10671:SF32 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=26042|UniProtKB=Q9NX00 Q9NX00 TMEM160 PTHR16236:SF0 TRANSMEMBRANE PROTEIN 160 TRANSMEMBRANE PROTEIN 160 HUMAN|HGNC=8793|UniProtKB=O60658 O60658 PDE8A PTHR11347:SF85 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8A hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;ERK1 and ERK2 cascade#GO:0070371;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 phosphodiesterase#PC00185 HUMAN|HGNC=12392|UniProtKB=Q99615 Q99615 DNAJC7 PTHR44200:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 chaperone#PC00072 HUMAN|HGNC=21368|UniProtKB=Q6IEG0 Q6IEG0 SNRNP48 PTHR21402:SF10 UNCHARACTERIZED U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN HUMAN|HGNC=6306|UniProtKB=O43731 O43731 KDELR3 PTHR10585:SF33 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR 3 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=4706|UniProtKB=P13807 P13807 GYS1 PTHR10176:SF2 GLYCOGEN SYNTHASE GLYCOGEN [STARCH] SYNTHASE, MUSCLE transferase activity, transferring hexosyl groups#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity, transferring glycosyl groups#GO:0016757;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glucan metabolic process#GO:0044042;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;glycogen metabolic process#GO:0005977;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;glycogen biosynthetic process#GO:0005978;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;cellular glucan metabolic process#GO:0006073;polysaccharide metabolic process#GO:0005976;glucan biosynthetic process#GO:0009250;cellular carbohydrate metabolic process#GO:0044262;oxidation-reduction process#GO:0055114;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;cellular polysaccharide biosynthetic process#GO:0033692;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Glycogen synthase D#P00709 HUMAN|HGNC=16097|UniProtKB=Q9UJQ1 Q9UJQ1 LAMP5 PTHR11506:SF35 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 5 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;cellular protein localization#GO:0034613;establishment of protein localization to organelle#GO:0072594;protein localization to organelle#GO:0033365;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=17842|UniProtKB=Q9UJY5 Q9UJY5 GGA1 PTHR45905:SF4 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1 HUMAN|HGNC=34236|UniProtKB=A6NKW6 A6NKW6 SHISAL2B PTHR31395:SF2 SHISA PROTEIN SHISA-LIKE-2B scaffold/adaptor protein#PC00226 HUMAN|HGNC=26196|UniProtKB=Q14CX5 Q14CX5 MFSD13A PTHR28658:SF3 TRANSMEMBRANE PROTEIN 180 TRANSMEMBRANE PROTEIN 180 HUMAN|HGNC=9847|UniProtKB=P43487 P43487 RANBP1 PTHR23138:SF135 RAN BINDING PROTEIN RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;nucleoside-triphosphatase activity#GO:0017111 regulation of microtubule-based process#GO:0032886;regulation of mitotic nuclear division#GO:0007088;positive regulation of organelle organization#GO:0010638;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;positive regulation of cell cycle process#GO:0090068;positive regulation of mitotic cell cycle#GO:0045931;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;positive regulation of biological process#GO:0048518;regulation of nuclear division#GO:0051783;regulation of organelle organization#GO:0033043;positive regulation of mitotic nuclear division#GO:0045840;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;positive regulation of cytoskeleton organization#GO:0051495;regulation of mitotic cell cycle#GO:0007346 envelope#GO:0031975;nuclear pore#GO:0005643;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=19290|UniProtKB=Q7Z408 Q7Z408 CSMD2 PTHR45656:SF6 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=14104|UniProtKB=Q5BKZ1 Q5BKZ1 ZNF326 PTHR12190:SF1 A-KINASE ANCHOR PROTEIN AKAP 8 DBIRD COMPLEX SUBUNIT ZNF326 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;regulation of DNA-templated transcription, elongation#GO:0032784;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;DNA-templated transcription, elongation#GO:0006354;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28920|UniProtKB=Q5SW79 Q5SW79 CEP170 PTHR15715:SF17 CENTROSOMAL PROTEIN OF 170 KDA CENTROSOMAL PROTEIN OF 170 KDA-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=29838|UniProtKB=Q9UHB4 Q9UHB4 NDOR1 PTHR19384:SF10 NITRIC OXIDE SYNTHASE-RELATED NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidoreductase#PC00176 HUMAN|HGNC=26103|UniProtKB=Q5VVM6 Q5VVM6 CCDC30 PTHR34479:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 30 COILED-COIL DOMAIN-CONTAINING PROTEIN 30 HUMAN|HGNC=32464|UniProtKB=A6NN14 A6NN14 ZNF729 PTHR24376:SF154 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 43-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28570|UniProtKB=Q9NQM4 Q9NQM4 DNAAF6 PTHR21083:SF0 TWISTER DYNEIN ASSEMBLY FACTOR 6, AXONEMAL HUMAN|HGNC=1014|UniProtKB=P11274 P11274 BCR PTHR23182:SF3 BREAKPOINT CLUSTER REGION PROTEIN BCR BREAKPOINT CLUSTER REGION PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein modulator#PC00022 HUMAN|HGNC=28062|UniProtKB=Q08AN1 Q08AN1 ZNF616 PTHR24377:SF649 IP01015P-RELATED ZINC FINGER PROTEIN 415-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=5013|UniProtKB=P09601 P09601 HMOX1 PTHR10720:SF1 HEME OXYGENASE HEME OXYGENASE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 cellular aromatic compound metabolic process#GO:0006725;inorganic ion homeostasis#GO:0098771;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;porphyrin-containing compound metabolic process#GO:0006778;response to oxidative stress#GO:0006979;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;iron ion homeostasis#GO:0055072;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;heterocycle metabolic process#GO:0046483;transition metal ion homeostasis#GO:0055076;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;pigment metabolic process#GO:0042440;cation homeostasis#GO:0055080;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;chemical homeostasis#GO:0048878;response to stimulus#GO:0050896;response to stress#GO:0006950;aromatic compound catabolic process#GO:0019439;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;metal ion homeostasis#GO:0055065 oxygenase#PC00177 HUMAN|HGNC=23476|UniProtKB=Q9H7D0 Q9H7D0 DOCK5 PTHR45653:SF3 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 5 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=22420|UniProtKB=Q9BT73 Q9BT73 PSMG3 PTHR31051:SF1 PROTEASOME ASSEMBLY CHAPERONE 3 PROTEASOME ASSEMBLY CHAPERONE 3 chaperone#PC00072 HUMAN|HGNC=9414|UniProtKB=Q13976 Q13976 PRKG1 PTHR24353:SF68 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE PROTEIN KINASE CGMP-DEPENDENT 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>cGK 1#P07149;Endothelin signaling pathway#P00019>PKG#P00567 HUMAN|HGNC=32456|UniProtKB=Q2TAA5 Q2TAA5 ALG11 PTHR45919:SF1 GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular lipid metabolic process#GO:0044255;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transferase#PC00220 HUMAN|HGNC=25951|UniProtKB=Q6ULP2 Q6ULP2 AFTPH PTHR16156:SF9 AFTIPHILIN A-RELATED AFTIPHILIN protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network transport vesicle#GO:0030140;trans-Golgi network#GO:0005802;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=25778|UniProtKB=Q2M296 Q2M296 MTHFSD PTHR13017:SF0 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE-RELATED METHENYLTETRAHYDROFOLATE SYNTHASE DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 HUMAN|HGNC=25044|UniProtKB=Q587J7 Q587J7 TDRD12 PTHR22948:SF31 TUDOR DOMAIN CONTAINING PROTEIN ATP-DEPENDENT RNA HELICASE TDRD12-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=4678|UniProtKB=P43080 P43080 GUCA1A PTHR23055:SF13 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 1 HUMAN|HGNC=11648|UniProtKB=P56279 P56279 TCL1A PTHR14060:SF4 PROTEIN P13 MTCP-1 T-CELL LEUKEMIA/LYMPHOMA PROTEIN 1A protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of protein modification process#GO:0031401;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=1631|UniProtKB=Q86VB7 Q86VB7 CD163 PTHR19331:SF441 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M130 serine protease#PC00203 HUMAN|HGNC=28744|UniProtKB=Q6PI25 Q6PI25 CNIH2 PTHR12290:SF13 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 2 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;signal transduction#GO:0007165;regulation of neurotransmitter receptor activity#GO:0099601;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;ionotropic glutamate receptor signaling pathway#GO:0035235;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;regulation of AMPA receptor activity#GO:2000311;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of signaling receptor activity#GO:0010469;response to stimulus#GO:0050896;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 synapse#GO:0045202;somatodendritic compartment#GO:0036477;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;dendrite#GO:0030425;organelle membrane#GO:0031090;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;cell projection#GO:0042995;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=16066|UniProtKB=Q9NUN7 Q9NUN7 ACER3 PTHR46187:SF3 ALKALINE CERAMIDASE 3 ALKALINE CERAMIDASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=26512|UniProtKB=Q5VW32 Q5VW32 BROX PTHR23032:SF1 UNCHARACTERIZED BRO1 DOMAIN-CONTAINING PROTEIN BROX HUMAN|HGNC=31709|UniProtKB=Q5H913 Q5H913 ARL13A PTHR46090:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13A vesicle targeting, to, from or within Golgi#GO:0048199;non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 bounding membrane of organelle#GO:0098588;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;motile cilium#GO:0031514;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=16828|UniProtKB=Q9BRL7 Q9BRL7 SEC22C PTHR46258:SF2 LONGIN DOMAIN-CONTAINING PROTEIN VESICLE-TRAFFICKING PROTEIN SEC22C HUMAN|HGNC=11882|UniProtKB=O14604 O14604 TMSB4Y PTHR12021:SF18 THYMOSIN BETA THYMOSIN BETA-4, Y-CHROMOSOMAL cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;cellular protein localization#GO:0034613;protein-containing complex assembly#GO:0065003;regulation of localization#GO:0032879;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;regulation of cellular component movement#GO:0051270;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of cell motility#GO:2000145;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;localization of cell#GO:0051674;actin polymerization or depolymerization#GO:0008154;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=30936|UniProtKB=P16415 P16415 ZNF823 PTHR24379:SF27 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 823 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=2579|UniProtKB=P08574 P08574 CYC1 PTHR10266:SF3 CYTOCHROME C1 CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL ATP synthesis#P02721>Cyt bc1#P02799;FAS signaling pathway#P00020>CytochromeC#P00620;Huntington disease#P00029>Cytochrome c#P00785 HUMAN|HGNC=11059|UniProtKB=Q9UPY5 Q9UPY5 SLC7A11 PTHR11785:SF323 AMINO ACID TRANSPORTER CYSTINE/GLUTAMATE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 transporter#PC00227 HUMAN|HGNC=5933|UniProtKB=A0A0B4J1Y8 A0A0B4J1Y8 IGLV9-49 PTHR23267:SF206 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 9-49 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=29170|UniProtKB=Q9Y2M0 Q9Y2M0 FAN1 PTHR15749:SF4 FANCONI-ASSOCIATED NUCLEASE 1 FANCONI-ASSOCIATED NUCLEASE 1 HUMAN|HGNC=33882|UniProtKB=Q9BT40 Q9BT40 INPP5K PTHR11200:SF117 INOSITOL 5-PHOSPHATASE INOSITOL POLYPHOSPHATE 5-PHOSPHATASE K hydrolase activity#GO:0016787;inositol phosphate phosphatase activity#GO:0052745;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of protein metabolic process#GO:0051246;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;oxidation-reduction process#GO:0055114;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;polysaccharide biosynthetic process#GO:0000271;response to oxygen-containing compound#GO:1901700;glycogen metabolic process#GO:0005977;negative regulation of signaling#GO:0023057;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;alcohol metabolic process#GO:0006066;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to nitrogen compound#GO:1901698;polysaccharide metabolic process#GO:0005976;small molecule catabolic process#GO:0044282;regulation of protein phosphorylation#GO:0001932;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;energy reserve metabolic process#GO:0006112;regulation of phosphorylation#GO:0042325;small molecule metabolic process#GO:0044281;monosaccharide metabolic process#GO:0005996;lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to peptide hormone#GO:0043434;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;biosynthetic process#GO:0009058;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biosynthetic process#GO:0009889;catabolic process#GO:0009056;regulation of macromolecule biosynthetic process#GO:0010556;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;carbohydrate biosynthetic process#GO:0016051;phospholipid dephosphorylation#GO:0046839;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;insulin receptor signaling pathway#GO:0008286;negative regulation of response to stimulus#GO:0048585;negative regulation of biosynthetic process#GO:0009890;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;glycogen biosynthetic process#GO:0005978;response to hormone#GO:0009725;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;peptidyl-serine modification#GO:0018209;hexose metabolic process#GO:0019318;cellular polysaccharide biosynthetic process#GO:0033692;glucan metabolic process#GO:0044042;regulation of protein modification process#GO:0031399;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;energy derivation by oxidation of organic compounds#GO:0015980;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;cellular glucan metabolic process#GO:0006073;negative regulation of protein modification process#GO:0031400;glucan biosynthetic process#GO:0009250;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;response to organonitrogen compound#GO:0010243;glycerophospholipid metabolic process#GO:0006650;negative regulation of protein metabolic process#GO:0051248;organophosphate catabolic process#GO:0046434;regulation of response to stimulus#GO:0048583;cellular carbohydrate metabolic process#GO:0044262;protein kinase B signaling#GO:0043491;organophosphate metabolic process#GO:0019637;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;regulation of phosphate metabolic process#GO:0019220;response to insulin#GO:0032868;macromolecule modification#GO:0043412;peptidyl-amino acid modification#GO:0018193;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular response to nitrogen compound#GO:1901699;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;phosphorylation#GO:0016310;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular macromolecule biosynthetic process#GO:0034645;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;glucose metabolic process#GO:0006006;regulation of glucose metabolic process#GO:0010906;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;cellular lipid metabolic process#GO:0044255;regulation of protein kinase B signaling#GO:0051896;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular polysaccharide metabolic process#GO:0044264 intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;cell leading edge#GO:0031252;endomembrane system#GO:0012505;intracellular#GO:0005622;ruffle#GO:0001726;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|Ensembl=ENSG00000283473|UniProtKB=A0A1B0GVK7 A0A1B0GVK7 FAM240A PTHR40387:SF3 PROTEIN FAM240B PROTEIN FAM240A HUMAN|HGNC=3435|UniProtKB=P19447 P19447 ERCC3 PTHR11274:SF0 RAD25/XP-B DNA REPAIR HELICASE GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB DNA helicase#PC00011 HUMAN|HGNC=8076|UniProtKB=O95156 O95156 NXPH2 PTHR17103:SF11 NEUREXOPHILIN NEUREXOPHILIN-2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 HUMAN|HGNC=9227|UniProtKB=Q9NQ55 Q9NQ55 PPAN PTHR12661:SF14 PETER PAN-RELATED SUPPRESSOR OF SWI4 1 HOMOLOG nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;rRNA binding#GO:0019843 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 HUMAN|HGNC=16175|UniProtKB=Q2I0M5 Q2I0M5 RSPO4 PTHR46987:SF6 FAMILY NOT NAMED R-SPONDIN-4 HUMAN|HGNC=1168|UniProtKB=Q9NQ34 Q9NQ34 TMEM9B PTHR13064:SF2 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER TRANSMEMBRANE PROTEIN 9B regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 HUMAN|HGNC=27040|UniProtKB=Q56A73 Q56A73 SPIN4 PTHR10405:SF9 SPINDLIN SPINDLIN-4 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7900|UniProtKB=P55786 P55786 NPEPPS PTHR11533:SF285 PROTEASE M1 ZINC METALLOPROTEASE PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED cation binding#GO:0043169;metallopeptidase activity#GO:0008237;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;peptide binding#GO:0042277;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;peptidase activity#GO:0008233;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=5129|UniProtKB=P31273 P31273 HOXC8 PTHR46166:SF4 HOMEOBOX DOMAIN-CONTAINING PROTEIN HOMEOBOX PROTEIN HOX-C8 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=673|UniProtKB=Q07960 Q07960 ARHGAP1 PTHR45808:SF6 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 1 GTPase-activating protein#PC00257 VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520;PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=28762|UniProtKB=Q9BVQ7 Q9BVQ7 SPATA5L1 PTHR23077:SF117 AAA-FAMILY ATPASE SPERMATOGENESIS-ASSOCIATED PROTEIN 5-LIKE PROTEIN 1 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 HUMAN|HGNC=33525|UniProtKB=P0C7X4 P0C7X4 FTH1P19 PTHR11431:SF97 FERRITIN FERRITIN HEAVY POLYPEPTIDE-LIKE 17-RELATED cation binding#GO:0043169;ferrous iron binding#GO:0008198;ferroxidase activity#GO:0004322;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;cellular cation homeostasis#GO:0030003;transition metal ion homeostasis#GO:0055076;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular iron ion homeostasis#GO:0006879;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;iron ion homeostasis#GO:0055072;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 storage protein#PC00210 HUMAN|HGNC=17157|UniProtKB=Q6P2E9 Q6P2E9 EDC4 PTHR15598:SF5 ENHANCER OF MRNA-DECAPPING PROTEIN 4 ENHANCER OF MRNA-DECAPPING PROTEIN 4 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 mRNA capping factor#PC00145 HUMAN|HGNC=12494|UniProtKB=Q13404 Q13404 UBE2V1 PTHR24068:SF323 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;protein K63-linked ubiquitination#GO:0070534;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Toll receptor signaling pathway#P00054>Uev1A#P01376 HUMAN|HGNC=18623|UniProtKB=Q96MW5 Q96MW5 COG8 PTHR21311:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;intra-Golgi vesicle-mediated transport#GO:0006891;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=21382|UniProtKB=A6NGQ2 A6NGQ2 OOEP PTHR19447:SF14 OOCYTE-EXPRESSED PROTEIN HOMOLOG-RELATED OOCYTE-EXPRESSED PROTEIN HOMOLOG nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 establishment or maintenance of cell polarity#GO:0007163;embryo development#GO:0009790;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;establishment or maintenance of apical/basal cell polarity#GO:0035088;multicellular organismal process#GO:0032501;cellular process#GO:0009987;pattern specification process#GO:0007389;establishment or maintenance of bipolar cell polarity#GO:0061245 cytoplasm#GO:0005737;cytoplasmic region#GO:0099568;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular#GO:0005622;apical part of cell#GO:0045177 HUMAN|HGNC=29502|UniProtKB=Q0ZLH3 Q0ZLH3 PJVK PTHR16399:SF10 GASDERMIN PEJVAKIN HUMAN|HGNC=132|UniProtKB=P60709 P60709 ACTB PTHR11937:SF192 ACTIN ACTIN, CYTOPLASMIC 1 actin and actin related protein#PC00039 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 HUMAN|HGNC=15880|UniProtKB=Q96SZ6 Q96SZ6 CDK5RAP1 PTHR43020:SF2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1 MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1 transferase activity#GO:0016740;4 iron, 4 sulfur cluster binding#GO:0051539;metal cluster binding#GO:0051540;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=16717|UniProtKB=Q7L7V1 Q7L7V1 DHX32 PTHR18934:SF88 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX32-RELATED nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA helicase#PC00032 HUMAN|HGNC=28854|UniProtKB=Q5HYK9 Q5HYK9 ZNF667 PTHR24390:SF46 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 667 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13384|UniProtKB=Q9H195 Q9H195 MUC3B PTHR24041:SF22 MUCIN MUCIN-3A-RELATED cell adhesion molecule#PC00069 HUMAN|HGNC=19399|UniProtKB=Q6P3X8 Q6P3X8 PGBD2 PTHR47055:SF2 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 2-RELATED sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 HUMAN|HGNC=8964|UniProtKB=Q14442 Q14442 PIGH PTHR15231:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H glycosyltransferase#PC00111 HUMAN|HGNC=7739|UniProtKB=P07196 P07196 NEFL PTHR45652:SF8 GLIAL FIBRILLARY ACIDIC PROTEIN NEUROFILAMENT LIGHT POLYPEPTIDE HUMAN|HGNC=15504|UniProtKB=Q9BX70 Q9BX70 BTBD2 PTHR45774:SF6 BTB/POZ DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN 2 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cellular process#GO:0009987;nervous system development#GO:0007399 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9400|UniProtKB=Q969G5 Q969G5 CAVIN3 PTHR15240:SF2 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 3 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cytoplasm#GO:0005737;plasma membrane raft#GO:0044853;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane region#GO:0098589;membrane microdomain#GO:0098857;whole membrane#GO:0098805;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=2621|UniProtKB=P33261 P33261 CYP2C19 PTHR24300:SF360 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2C19 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=14171|UniProtKB=Q96A99 Q96A99 PTX4 PTHR19277:SF122 PENTRAXIN PENTRAXIN-4 HUMAN|HGNC=33744|UniProtKB=Q7Z7N9 Q7Z7N9 TMEM179B PTHR31056:SF1 TRANSMEMBRANE PROTEIN 179B TRANSMEMBRANE PROTEIN 179B HUMAN|Ensembl=ENSG00000281185|UniProtKB=A3KN74 A3KN74 GPX6 PTHR11592:SF32 GLUTATHIONE PEROXIDASE GPX6 PROTEIN-RELATED oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;binding#GO:0005488;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180 HUMAN|HGNC=21401|UniProtKB=Q96KF7 Q96KF7 SMIM8 PTHR14274:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 8 SMALL INTEGRAL MEMBRANE PROTEIN 8 HUMAN|HGNC=17150|UniProtKB=Q9Y2V2 Q9Y2V2 CARHSP1 PTHR12962:SF3 CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED CALCIUM-REGULATED HEAT-STABLE PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of catabolic process#GO:0009894;regulation of mRNA catabolic process#GO:0061013;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;regulation of RNA stability#GO:0043487;cellular nitrogen compound metabolic process#GO:0034641;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=24793|UniProtKB=Q6ZS72 Q6ZS72 PEAK3 PTHR22972:SF6 SERINE/THREONINE PROTEIN KINASE PROTEIN PEAK3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;anchoring junction#GO:0070161;intracellular#GO:0005622;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=14329|UniProtKB=Q9NS25 Q9NS25 SPANXB1 PTHR23425:SF16 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME A-RELATED HUMAN|HGNC=3345|UniProtKB=O14682 O14682 ENC1 PTHR24410:SF5 HL07962P-RELATED ECTODERM-NEURAL CORTEX PROTEIN 1 HUMAN|HGNC=9822|UniProtKB=O15315 O15315 RAD51B PTHR46456:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 2 DNA REPAIR PROTEIN RAD51 HOMOLOG 2 DNA metabolism protein#PC00009 HUMAN|HGNC=25521|UniProtKB=Q8N5C6 Q8N5C6 SRBD1 PTHR10724:SF10 30S RIBOSOMAL PROTEIN S1 S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribosomal protein#PC00202 HUMAN|HGNC=7033|UniProtKB=P55001 P55001 MFAP2 PTHR16485:SF3 MICROFIBRILLAR-ASSOCIATED PROTEIN 2 MICROFIBRILLAR-ASSOCIATED PROTEIN 2 embryonic organ morphogenesis#GO:0048562;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;system development#GO:0048731;embryonic organ development#GO:0048568;embryo development#GO:0009790;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423;embryonic morphogenesis#GO:0048598 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;collagen-containing extracellular matrix#GO:0062023;extracellular region#GO:0005576 HUMAN|HGNC=11212|UniProtKB=Q07617 Q07617 SPAG1 PTHR45984:SF3 RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG SPERM-ASSOCIATED ANTIGEN 1 heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;protein localization to mitochondrion#GO:0070585;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;axonemal dynein complex assembly#GO:0070286;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;mitochondrion organization#GO:0007005;vesicle localization#GO:0051648;establishment of protein localization to organelle#GO:0072594;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;mitochondrial transport#GO:0006839;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11366|UniProtKB=P42229 P42229 STAT5A PTHR11801:SF47 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5A cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;defense response#GO:0006952;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;response to peptide hormone#GO:0043434;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;regulation of transcription, DNA-templated#GO:0006355;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;organic cyclic compound biosynthetic process#GO:1901362;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>STAT#P01173;JAK/STAT signaling pathway#P00038>STAT#P01027;Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561 HUMAN|HGNC=16976|UniProtKB=Q7Z465 Q7Z465 BNIPL PTHR12112:SF21 BNIP - RELATED BCL-2/ADENOVIRUS E1B 19 KDA-INTERACTING PROTEIN 2-LIKE PROTEIN pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;phosphorus metabolic process#GO:0006793;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=6190|UniProtKB=P23458 P23458 JAK1 PTHR45807:SF5 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE JAK1 Interferon-gamma signaling pathway#P00035>Jak1#P00953;Angiogenesis#P00005>JAK1#P00185;PDGF signaling pathway#P00047>Jak#P01155;JAK/STAT signaling pathway#P00038>Jak#P01034 HUMAN|HGNC=25691|UniProtKB=Q8N9V6 Q8N9V6 ANKRD53 PTHR24160:SF1 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 53 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 53 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;positive regulation of supramolecular fiber organization#GO:1902905;membrane organization#GO:0061024;nuclear division#GO:0000280;regulation of cellular component organization#GO:0051128;regulation of cell division#GO:0051302;microtubule polymerization or depolymerization#GO:0031109;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of cytokinesis#GO:0032465;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;cellular protein-containing complex assembly#GO:0034622;sister chromatid segregation#GO:0000819;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;mitotic metaphase plate congression#GO:0007080;chromosome localization#GO:0050000;regulation of microtubule-based process#GO:0032886;cell division#GO:0051301;mitotic spindle organization#GO:0007052;positive regulation of organelle organization#GO:0010638;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;regulation of mitotic spindle organization#GO:0060236;mitotic cytokinesis#GO:0000281;metaphase plate congression#GO:0051310;regulation of protein-containing complex assembly#GO:0043254;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;cytokinesis#GO:0000910;membrane fission#GO:0090148;establishment of chromosome localization#GO:0051303;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;positive regulation of protein-containing complex assembly#GO:0031334;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;microtubule-based process#GO:0007017;organelle organization#GO:0006996;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;positive regulation of cytoskeleton organization#GO:0051495;regulation of mitotic cell cycle#GO:0007346 intracellular non-membrane-bounded organelle#GO:0043232;spindle pole#GO:0000922;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229 HUMAN|HGNC=19868|UniProtKB=Q8TEW6 Q8TEW6 DOK4 PTHR21258:SF44 DOCKING PROTEIN RELATED DOCKING PROTEIN 4 HUMAN|HGNC=30880|UniProtKB=Q9NZ45 Q9NZ45 CISD1 PTHR13680:SF40 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 metal cluster binding#GO:0051540;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=23472|UniProtKB=Q96A46 Q96A46 SLC25A28 PTHR45758:SF4 MITOFERRIN-1-RELATED MITOFERRIN-2 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;iron ion transmembrane transporter activity#GO:0005381;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;iron ion transmembrane transport#GO:0034755;mitochondrial transport#GO:0006839;localization#GO:0051179;establishment of localization#GO:0051234;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;mitochondrial transmembrane transport#GO:1990542 HUMAN|HGNC=18877|UniProtKB=P59540 P59540 TAS2R46 PTHR11394:SF66 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 46 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=29231|UniProtKB=Q9ULG3 Q9ULG3 CFAP92 PTHR33667:SF7 SI:DKEY-57N24.6 DUF4550 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=7994|UniProtKB=Q92823 Q92823 NRCAM PTHR44170:SF15 PROTEIN SIDEKICK NEURONAL CELL ADHESION MOLECULE HUMAN|HGNC=7764|UniProtKB=Q92886 Q92886 NEUROG1 PTHR19290:SF130 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=17855|UniProtKB=O94923 O94923 GLCE PTHR13174:SF3 D-GLUCURONYL C5-EPIMERASE D-GLUCURONYL C5-EPIMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;heparan sulfate proteoglycan metabolic process#GO:0030201;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 isomerase#PC00135 HUMAN|HGNC=471|UniProtKB=P49418 P49418 AMPH PTHR46514:SF2 AMPHIPHYSIN AMPHIPHYSIN lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=3311|UniProtKB=P30740 P30740 SERPINB1 PTHR11461:SF180 SERINE PROTEASE INHIBITOR, SERPIN LEUKOCYTE ELASTASE INHIBITOR serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=17967|UniProtKB=Q9NWZ3 Q9NWZ3 IRAK4 PTHR24419:SF35 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;nuclear division#GO:0000280;cell cycle process#GO:0022402;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 Toll receptor signaling pathway#P00054>IRAK4#P01342 HUMAN|HGNC=26883|UniProtKB=Q8N7L0 Q8N7L0 FAM216B PTHR16476:SF3 FAMILY NOT NAMED PROTEIN FAM216B HUMAN|HGNC=11587|UniProtKB=Q12788 Q12788 TBL3 PTHR19854:SF15 TRANSDUCIN BETA-LIKE 3 TRANSDUCIN BETA-LIKE PROTEIN 3 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;cleavage involved in rRNA processing#GO:0000469;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;endonucleolytic cleavage involved in rRNA processing#GO:0000478;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 scaffold/adaptor protein#PC00226 HUMAN|HGNC=10979|UniProtKB=P53007 P53007 SLC25A1 PTHR45788:SF4 SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL transmembrane transport#GO:0055085;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;citrate transport#GO:0015746;anion transmembrane transport#GO:0098656;mitochondrial transport#GO:0006839;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 transporter#PC00227 HUMAN|HGNC=18150|UniProtKB=Q8IUG5 Q8IUG5 MYO18B PTHR45615:SF8 MYOSIN HEAVY CHAIN, NON-MUSCLE UNCONVENTIONAL MYOSIN-XVIIIB Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=12382|UniProtKB=Q9H0U9 Q9H0U9 TSPYL1 PTHR11875:SF64 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 1 protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=4071|UniProtKB=Q06546 Q06546 GABPA PTHR11849:SF195 ETS GA-BINDING PROTEIN ALPHA CHAIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=10333|UniProtKB=P62888 P62888 RPL30 PTHR11449:SF1 RIBOSOMAL PROTEIN L30 60S RIBOSOMAL PROTEIN L30 ribosomal protein#PC00202 HUMAN|HGNC=13287|UniProtKB=A6NMB9 A6NMB9 FIGNL2 PTHR23074:SF33 AAA DOMAIN-CONTAINING FIDGETIN-LIKE PROTEIN 2 pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;ATPase activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=27558|UniProtKB=Q4G0I0 Q4G0I0 CCSMST1 PTHR35268:SF1 PROTEIN CCSMST1 PROTEIN CCSMST1 HUMAN|HGNC=4642|UniProtKB=P0CG29 P0CG29 GSTT2 PTHR43917:SF4 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE THETA-2-RELATED transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=26906|UniProtKB=Q5K4E3 Q5K4E3 PRSS36 PTHR24276:SF62 POLYSERASE-RELATED POLYSERASE-2 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 HUMAN|HGNC=1713|UniProtKB=Q8IWY9 Q8IWY9 CDAN1 PTHR28678:SF1 CODANIN-1 CODANIN-1 HUMAN|HGNC=31689|UniProtKB=Q6ZN16 Q6ZN16 MAP3K15 PTHR11584:SF363 SERINE/THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 15 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=9834|UniProtKB=Q7Z5J4 Q7Z5J4 RAI1 PTHR14955:SF6 RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 20 RETINOIC ACID-INDUCED PROTEIN 1 positive regulation of gene expression#GO:0010628;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=24029|UniProtKB=P58166 P58166 INHBE PTHR11848:SF6 TGF-BETA FAMILY INHIBIN BETA E CHAIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=24165|UniProtKB=Q9BXX2 Q9BXX2 ANKRD30B PTHR24147:SF52 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 30B HUMAN|HGNC=14120|UniProtKB=P20231 P20231 TPSB2 PTHR24256:SF521 TRYPTASE-RELATED TRYPTASE ALPHA/BETA-1-RELATED serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=26047|UniProtKB=Q8WUE5 Q8WUE5 CT55 PTHR45418:SF1 CANCER/TESTIS ANTIGEN 55 CANCER/TESTIS ANTIGEN 55 HUMAN|HGNC=16999|UniProtKB=Q92989 Q92989 CLP1 PTHR12755:SF6 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=11255|UniProtKB=P10451 P10451 SPP1 PTHR10607:SF1 OSTEOPONTIN OSTEOPONTIN cytokine#PC00083 HUMAN|HGNC=23222|UniProtKB=Q96N96 Q96N96 SPATA13 PTHR45834:SF5 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 13 guanyl-nucleotide exchange factor#PC00113 HUMAN|Ensembl=ENSG00000234409|UniProtKB=H7C350 H7C350 CCDC188 PTHR22422:SF6 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5B-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 188 HUMAN|HGNC=15211|UniProtKB=Q8NGF0 Q8NGF0 OR52B6 PTHR26450:SF32 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52B6 transmembrane signal receptor#PC00197 HUMAN|HGNC=1637|UniProtKB=P15813 P15813 CD1D PTHR16675:SF175 MHC CLASS I-RELATED ANTIGEN-PRESENTING GLYCOPROTEIN CD1D lipid binding#GO:0008289;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 immune response#GO:0006955;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;T cell mediated immunity#GO:0002456;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=21532|UniProtKB=Q92543 Q92543 SNX19 PTHR22775:SF31 SORTING NEXIN SORTING NEXIN-19 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3557|UniProtKB=P05413 P05413 FABP3 PTHR11955:SF61 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, HEART HUMAN|HGNC=9454|UniProtKB=O43490 O43490 PROM1 PTHR22730:SF3 PROMININ PROM PROTEIN PROMININ-1 lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;cholesterol binding#GO:0015485;steroid binding#GO:0005496;sterol binding#GO:0032934 supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;actin filament#GO:0005884;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;non-membrane-bounded organelle#GO:0043228;cell surface#GO:0009986;intrinsic component of membrane#GO:0031224;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microvillus#GO:0005902;extracellular region#GO:0005576;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=4562|UniProtKB=Q13588 Q13588 GRAP PTHR46037:SF2 PROTEIN ENHANCER OF SEVENLESS 2B GRB2-RELATED ADAPTER PROTEIN PDGF signaling pathway#P00047>Grb2#P01148;Angiogenesis#P00005>Grb2#P00234;FGF signaling pathway#P00021>Grb2#P00631;Angiogenesis#P00005>Grb2#P00252;EGF receptor signaling pathway#P00018>Grb2#P00550;Integrin signalling pathway#P00034>Grb2#P00910;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Grb#P00848;B cell activation#P00010>Grb2#P00372 HUMAN|HGNC=12854|UniProtKB=P27348 P27348 YWHAQ PTHR18860:SF3 14-3-3 PROTEIN 14-3-3 PROTEIN THETA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 HUMAN|HGNC=33547|UniProtKB=Q8TBE3 Q8TBE3 FNDC9 PTHR37361:SF2 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 9 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 9 HUMAN|HGNC=6106|UniProtKB=Q9BZS1 Q9BZS1 FOXP3 PTHR45796:SF5 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10866|UniProtKB=Q11203 Q11203 ST3GAL3 PTHR13713:SF37 SIALYLTRANSFERASE CMP-N-ACETYLNEURAMINATE-BETA-1,4-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=10360|UniProtKB=P46777 P46777 RPL5 PTHR23410:SF24 RIBOSOMAL PROTEIN L5-RELATED 60S RIBOSOMAL PROTEIN L5 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=8284|UniProtKB=P47888 P47888 OR3A3 PTHR48001:SF147 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A3 transmembrane signal receptor#PC00197 HUMAN|HGNC=4138|UniProtKB=Q14697 Q14697 GANAB PTHR22762:SF54 ALPHA-GLUCOSIDASE NEUTRAL ALPHA-GLUCOSIDASE AB glucosidase#PC00108 HUMAN|HGNC=14124|UniProtKB=Q12980 Q12980 NPRL3 PTHR13153:SF5 CGTHBA PROTEIN -14 GENE PROTEIN GATOR COMPLEX PROTEIN NPRL3 cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;regulation of cellular component organization#GO:0051128;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of macroautophagy#GO:0016241;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;regulation of cellular process#GO:0050794;autophagosome organization#GO:1905037;negative regulation of signal transduction#GO:0009968;autophagosome assembly#GO:0000045;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of autophagosome assembly#GO:2000785;process utilizing autophagic mechanism#GO:0061919;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;TORC1 signaling#GO:0038202;negative regulation of response to stimulus#GO:0048585;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;organelle assembly#GO:0070925;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cellular response to nutrient levels#GO:0031669;organelle organization#GO:0006996;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198 protein-containing complex#GO:0032991 HUMAN|HGNC=14307|UniProtKB=Q9BTT6 Q9BTT6 LRRC1 PTHR48051:SF10 FAMILY NOT NAMED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 1 HUMAN|HGNC=1191|UniProtKB=Q9Y6B2 Q9Y6B2 EID1 PTHR15556:SF5 EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 2-RELATED EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 1 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5302|UniProtKB=P34969 P34969 HTR7 PTHR24247:SF116 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 7 cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=12480|UniProtKB=Q969M7 Q969M7 UBE2F PTHR24068:SF194 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBE2F ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=11403|UniProtKB=Q9Y6E0 Q9Y6E0 STK24 PTHR48012:SF22 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE/THREONINE-PROTEIN KINASE 24 HUMAN|HGNC=25482|UniProtKB=Q9NWB6 Q9NWB6 ARGLU1 PTHR31711:SF1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=20987|UniProtKB=Q9P2S6 Q9P2S6 ANKMY1 PTHR15897:SF2 ANKYRIN REPEAT AND MYND DOMAIN PROTEIN 1 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=11312|UniProtKB=P19474 P19474 TRIM21 PTHR24103:SF46 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM21 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;protein homodimerization activity#GO:0042803;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;identical protein binding#GO:0042802;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;kinase binding#GO:0019900 regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;aromatic compound biosynthetic process#GO:0019438;positive regulation of autophagy#GO:0010508;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=25874|UniProtKB=Q9H3U5 Q9H3U5 MFSD1 PTHR23512:SF3 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 HUMAN|Ensembl=ENSG00000283324|UniProtKB=A0A1B0GV90 A0A1B0GV90 CTXND2 PTHR16736:SF6 CORTEXIN-1-RELATED CORTEXIN DOMAIN CONTAINING 2 HUMAN|HGNC=21729|UniProtKB=Q7Z5L9 Q7Z5L9 IRF2BP2 PTHR10816:SF18 MYELIN TRANSCRIPTION FACTOR 1-RELATED INTERFERON REGULATORY FACTOR 2-BINDING PROTEIN 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;transcription corepressor activity#GO:0003714 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=53643|UniProtKB=A6NCN8 A6NCN8 TEX52 PTHR35156:SF1 TESTIS-EXPRESSED PROTEIN 52 TESTIS-EXPRESSED PROTEIN 52 HUMAN|HGNC=14101|UniProtKB=Q9UIV1 Q9UIV1 CNOT7 PTHR10797:SF2 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cellular protein metabolic process#GO:0032269;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;intracellular#GO:0005622;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=6617|UniProtKB=P38571 P38571 LIPA PTHR11005:SF26 LYSOSOMAL ACID LIPASE-RELATED LYSOSOMAL ACID LIPASE/CHOLESTERYL ESTER HYDROLASE lipase#PC00143 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol esterase#P02830 HUMAN|HGNC=8742|UniProtKB=P48539 P48539 PCP4 PTHR15359:SF7 IG-LIKE DOMAIN-CONTAINING PROTEIN CALMODULIN REGULATOR PROTEIN PCP4 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;calmodulin binding#GO:0005516;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 HUMAN|HGNC=8787|UniProtKB=P51160 P51160 PDE6C PTHR11347:SF23 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA' hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 phosphodiesterase#PC00185 HUMAN|HGNC=15019|UniProtKB=P0C7T2 P0C7T2 OR2T7 PTHR26453:SF78 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T27-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=18362|UniProtKB=Q9BZV3 Q9BZV3 IMPG2 PTHR12199:SF4 INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN 2 carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;heparin binding#GO:0008201;ion binding#GO:0043167;organic acid binding#GO:0043177;anion binding#GO:0043168;glycosaminoglycan binding#GO:0005539 extracellular matrix protein#PC00102 HUMAN|HGNC=5157|UniProtKB=P00492 P00492 HPRT1 PTHR43340:SF6 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE cation binding#GO:0043169;transferase activity#GO:0016740;magnesium ion binding#GO:0000287;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase metabolic process#GO:0009112;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;pigment biosynthetic process#GO:0046148;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;IMP metabolic process#GO:0046040;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine nucleoside monophosphate metabolic process#GO:0009126;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribose phosphate biosynthetic process#GO:0046390;ribonucleoside monophosphate metabolic process#GO:0009161;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase biosynthetic process#GO:0009113;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 glycosyltransferase#PC00111 Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245;Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247 HUMAN|HGNC=17156|UniProtKB=Q9Y6Y9 Q9Y6Y9 LY96 PTHR15218:SF0 MD-1, MD-2 - RELATED LYMPHOCYTE ANTIGEN 96 carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;binding#GO:0005488 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;cellular response to lipopolysaccharide#GO:0071222;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to lipid#GO:0033993;pattern recognition receptor signaling pathway#GO:0002221;detection of chemical stimulus#GO:0009593;toll-like receptor 4 signaling pathway#GO:0034142;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;regulation of signal transduction#GO:0009966;response to molecule of bacterial origin#GO:0002237;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;detection of stimulus#GO:0051606;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of response to biotic stimulus#GO:0002833 receptor complex#GO:0043235;membrane protein complex#GO:0098796;cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of membrane#GO:0016021;membrane#GO:0016020 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>MD-2#P01347 HUMAN|HGNC=16862|UniProtKB=Q92565 Q92565 RAPGEF5 PTHR23113:SF26 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 5 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=20165|UniProtKB=Q9P2P1 Q9P2P1 NYNRIN PTHR12876:SF2 N4BP1-RELATED PROTEIN NYNRIN catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 endoribonuclease#PC00094 HUMAN|HGNC=30827|UniProtKB=O95990 O95990 FAM107A PTHR16768:SF3 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A ACTIN-ASSOCIATED PROTEIN FAM107A cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036;protein-containing complex subunit organization#GO:0043933 actomyosin#GO:0042641;supramolecular complex#GO:0099080;synapse#GO:0045202;actin filament bundle#GO:0032432;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=9882|UniProtKB=Q9NS23 Q9NS23 RASSF1 PTHR22738:SF12 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15718|UniProtKB=Q8J025 Q8J025 APCDD1 PTHR31021:SF2 ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 PROTEIN APCDD1 protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=16236|UniProtKB=Q9H1R2 Q9H1R2 DUSP15 PTHR45948:SF4 DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED DUAL SPECIFICITY PROTEIN PHOSPHATASE 15 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;transforming growth factor beta receptor signaling pathway#GO:0007179;regulation of intracellular signal transduction#GO:1902531;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=7729|UniProtKB=Q15019 Q15019 SEPTIN2 PTHR18884:SF67 SEPTIN SEPTIN-2 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;cell division#GO:0051301;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;cytokinesis#GO:0000910;membrane fission#GO:0090148;vesicle localization#GO:0051648;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;cell cycle#GO:0007049 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 HUMAN|HGNC=15924|UniProtKB=Q9UJQ4 Q9UJQ4 SALL4 PTHR23233:SF19 SAL-LIKE PROTEIN SAL-LIKE PROTEIN 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=10480|UniProtKB=Q8N488 Q8N488 RYBP PTHR12920:SF3 RYBP AND YAF2-RELATED RING1 AND YY1-BINDING PROTEIN nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=341|UniProtKB=P21549 P21549 AGXT PTHR21152:SF24 AMINOTRANSFERASE CLASS V SERINE--PYRUVATE AMINOTRANSFERASE transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transaminase#PC00216 Pyridoxal-5-phosphate biosynthesis#P02759>Phosphohydroxythreonine aminotransferase#P03058;Serine glycine biosynthesis#P02776>Phosphoserine aminotransferase#P03157 HUMAN|HGNC=29114|UniProtKB=O94868 O94868 FCHSD2 PTHR15735:SF11 FCH AND DOUBLE SH3 DOMAINS PROTEIN F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 2 cellular component biogenesis#GO:0044085;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;synaptic signaling#GO:0099536;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;neuromuscular synaptic transmission#GO:0007274;regulation of protein polymerization#GO:0032271;cell-cell signaling#GO:0007267;signaling#GO:0023052;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;trans-synaptic signaling#GO:0099537;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 HUMAN|Ensembl=ENSG00000286105|UniProtKB=A0A494BZU4 A0A494BZU4 TMEM217 PTHR34928:SF3 TRANSMEMBRANE PROTEIN 217 TRANSMEMBRANE PROTEIN 217 HUMAN|HGNC=32257|UniProtKB=A6NNJ1 A6NNJ1 FAM90A9P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=10913|UniProtKB=Q9UP95 Q9UP95 SLC12A4 PTHR11827:SF46 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;chemical synaptic transmission#GO:0007268;ion homeostasis#GO:0050801;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;signaling#GO:0023052;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cell communication#GO:0007154;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;regulation of cellular component size#GO:0032535;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065 secondary carrier transporter#PC00258 HUMAN|HGNC=6339|UniProtKB=P43630 P43630 KIR3DL2 PTHR11738:SF166 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL1-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=2197|UniProtKB=P02452 P02452 COL1A1 PTHR24023:SF569 COLLAGEN ALPHA COLLAGEN ALPHA-1(I) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=15743|UniProtKB=Q96PL5 Q96PL5 ERMAP PTHR24100:SF46 BUTYROPHILIN ERYTHROID MEMBRANE-ASSOCIATED PROTEIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=28218|UniProtKB=Q9BRA2 Q9BRA2 TXNDC17 PTHR12452:SF0 42-9-9 PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transporter#PC00227 HUMAN|HGNC=15970|UniProtKB=Q9NRJ5 Q9NRJ5 PAPOLB PTHR10682:SF19 POLY A POLYMERASE POLY(A) POLYMERASE BETA adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=16392|UniProtKB=Q9H0X9 Q9H0X9 OSBPL5 PTHR10972:SF169 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 5 lipid binding#GO:0008289;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;lipid transporter activity#GO:0005319;steroid binding#GO:0005496;sterol binding#GO:0032934 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3278|UniProtKB=O15371 O15371 EIF3D PTHR12399:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=17996|UniProtKB=Q8N159 Q8N159 NAGS PTHR23342:SF0 N-ACETYLGLUTAMATE SYNTHASE N-ACETYLGLUTAMATE SYNTHASE, MITOCHONDRIAL cation binding#GO:0043169;amino acid binding#GO:0016597;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;transferase activity, transferring phosphorus-containing groups#GO:0016772;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;kinase activity#GO:0016301 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 Arginine biosynthesis#P02728>N-acetylglutamate synthase#P02848 HUMAN|HGNC=3642|UniProtKB=P22570 P22570 FDXR PTHR11938:SF91 FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE NADPH:ADRENODOXIN OXIDOREDUCTASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FdxR#P04604 HUMAN|HGNC=27829|UniProtKB=Q7Z388 Q7Z388 DPY19L4 PTHR31488:SF2 DPY-19-LIKE 1, LIKE (H. SAPIENS) C-MANNOSYLTRANSFERASE DPY19L4-RELATED transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=8135|UniProtKB=P23515 P23515 OMG PTHR47114:SF2 FAMILY NOT NAMED OLIGODENDROCYTE-MYELIN GLYCOPROTEIN HUMAN|HGNC=11307|UniProtKB=P08240 P08240 SRPRA PTHR43134:SF1 SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cellular anatomical entity#GO:0110165;membrane#GO:0016020 G-protein#PC00020 HUMAN|HGNC=26878|UniProtKB=A6NFQ2 A6NFQ2 TCAF2 PTHR15730:SF4 EXPERIMENTAL AUTOIMMUNE PROSTATITIS ANTIGEN 2-RELATED PEPTIDASE M60 DOMAIN-CONTAINING PROTEIN-RELATED regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;negative regulation of transport#GO:0051051;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;regulation of ion transmembrane transporter activity#GO:0032412;anion transmembrane transport#GO:0098656;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;anion transport#GO:0006820;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;negative regulation of cellular process#GO:0048523;inorganic anion transport#GO:0015698;negative regulation of molecular function#GO:0044092 HUMAN|HGNC=10638|UniProtKB=O14625 O14625 CXCL11 PTHR10179:SF84 CXC CHEMOKINE C-X-C MOTIF CHEMOKINE 11 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=13805|UniProtKB=Q9H2A3 Q9H2A3 NEUROG2 PTHR19290:SF105 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=3584|UniProtKB=Q00597 Q00597 FANCC PTHR16798:SF0 FANCONI ANEMIA GROUP C PROTEIN FANCC FANCONI ANEMIA GROUP C PROTEIN DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;response to oxidative stress#GO:0006979;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;cellular response to chemical stress#GO:0062197;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;Fanconi anaemia nuclear complex#GO:0043240;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3718|UniProtKB=P26885 P26885 FKBP2 PTHR45779:SF3 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2 TGF-beta signaling pathway#P00052>FKBP12#P01288 HUMAN|HGNC=5111|UniProtKB=P14653 P14653 HOXB1 PTHR45946:SF5 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN HOX-B1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=24326|UniProtKB=Q96DM3 Q96DM3 RMC1 PTHR12897:SF4 COLON CANCER-ASSOCIATED PROTEIN MIC1 REGULATOR OF MON1-CCZ1 COMPLEX regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;biological regulation#GO:0065007;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=14344|UniProtKB=Q9BXJ0 Q9BXJ0 C1QTNF5 PTHR15427:SF27 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 5 HUMAN|HGNC=16145|UniProtKB=Q96M20 Q96M20 CNBD2 PTHR23011:SF35 UNCHARACTERIZED CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;multi-organism process#GO:0051704;multicellular organismal reproductive process#GO:0048609 HUMAN|HGNC=24034|UniProtKB=Q8WTT2 Q8WTT2 NOC3L PTHR14428:SF5 NUCLEOLAR COMPLEX PROTEIN 3 NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG chromatin binding#GO:0003682;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=3003|UniProtKB=Q9BZG8 Q9BZG8 DPH1 PTHR10762:SF1 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=4921|UniProtKB=P31629 P31629 HIVEP2 PTHR45944:SF1 SCHNURRI, ISOFORM F TRANSCRIPTION FACTOR HIVEP2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18638|UniProtKB=Q5T7P8 Q5T7P8 SYT6 PTHR10024:SF45 SYNAPTOTAGMIN SYNAPTOTAGMIN-6 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;syntaxin binding#GO:0019905;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cation transport#GO:0006812;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;response to metal ion#GO:0010038;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;exocytosis#GO:0006887;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of ion transport#GO:0043269;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 HUMAN|HGNC=24274|UniProtKB=Q9Y5J1 Q9Y5J1 UTP18 PTHR18359:SF2 WD-REPEAT PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 HUMAN|HGNC=24025|UniProtKB=Q9GZN1 Q9GZN1 ACTR6 PTHR11937:SF47 ACTIN ACTIN-RELATED PROTEIN 6 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;protein-DNA complex subunit organization#GO:0071824;histone exchange#GO:0043486;nucleosome organization#GO:0034728;organelle organization#GO:0006996;chromosome organization#GO:0051276;ATP-dependent chromatin remodeling#GO:0043044;chromatin organization#GO:0006325;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 actin and actin related protein#PC00039 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Huntington disease#P00029>Actin#P00807;Cadherin signaling pathway#P00012>F-actin#P00470 HUMAN|HGNC=16367|UniProtKB=Q14585 Q14585 ZNF345 PTHR24393:SF88 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 345-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=34522|UniProtKB=Q6UXS0 Q6UXS0 CLEC19A PTHR22802:SF427 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 19 MEMBER A membrane traffic protein#PC00150 HUMAN|HGNC=82|UniProtKB=P09110 P09110 ACAA1 PTHR43853:SF8 3-KETOACYL-COA THIOLASE, PEROXISOMAL 3-KETOACYL-COA THIOLASE, PEROXISOMAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;organic cyclic compound metabolic process#GO:1901360;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;response to chemical#GO:0042221;organic cyclic compound catabolic process#GO:1901361;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 acetyltransferase#PC00038 HUMAN|HGNC=11737|UniProtKB=Q8IWB6 Q8IWB6 TEX14 PTHR23060:SF1 TESTIS EXPRESSED GENE 14 INACTIVE SERINE/THREONINE-PROTEIN KINASE TEX14 negative regulation of sister chromatid segregation#GO:0033046;male gamete generation#GO:0048232;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of mitotic sister chromatid segregation#GO:0033047;reproductive process#GO:0022414;attachment of spindle microtubules to kinetochore#GO:0008608;negative regulation of cellular component organization#GO:0051129;male meiotic nuclear division#GO:0007140;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;gamete generation#GO:0007276;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;mitotic cell cycle phase transition#GO:0044772;cellular process involved in reproduction in multicellular organism#GO:0022412;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;mitotic spindle assembly checkpoint#GO:0007094;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;mitotic cell cycle checkpoint#GO:0007093;regulation of nuclear division#GO:0051783;multicellular organism reproduction#GO:0032504;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;multi-organism process#GO:0051704;metaphase/anaphase transition of cell cycle#GO:0044784;negative regulation of chromosome separation#GO:1905819;extracellular structure organization#GO:0043062;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;extracellular region#GO:0005576;midbody#GO:0030496;intracellular#GO:0005622;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=1375|UniProtKB=P22748 P22748 CA4 PTHR18952:SF95 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 4 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=29531|UniProtKB=Q6PKG0 Q6PKG0 LARP1 PTHR22792:SF51 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 1 RNA metabolism protein#PC00031 HUMAN|HGNC=7899|UniProtKB=Q9NQX5 Q9NQX5 NPDC1 PTHR23352:SF2 NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN-1 NPDC-1 PROTEIN NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN 1 HUMAN|HGNC=16397|UniProtKB=Q9BXB4 Q9BXB4 OSBPL11 PTHR10972:SF46 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 11 lipid binding#GO:0008289;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;lipid transporter activity#GO:0005319;steroid binding#GO:0005496;sterol binding#GO:0032934 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16078|UniProtKB=Q9H169 Q9H169 STMN4 PTHR10104:SF6 STATHMIN STATHMIN-4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cellular protein complex disassembly#GO:0043624;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 Cytoskeletal regulation by Rho GTPase#P00016>Op18/stathmin#P00513 HUMAN|HGNC=17824|UniProtKB=Q9NWW9 Q9NWW9 PLAAT2 PTHR13943:SF33 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 2 transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=1462|UniProtKB=Q13557 Q13557 CAMK2D PTHR24347:SF365 SERINE/THREONINE-PROTEIN KINASE CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT DELTA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 HUMAN|HGNC=25157|UniProtKB=Q96ES6 Q96ES6 MFSD3 PTHR12778:SF10 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 3 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;carbohydrate derivative transport#GO:1901264;transport#GO:0006810 secondary carrier transporter#PC00258 HUMAN|HGNC=25740|UniProtKB=Q5JTW2 Q5JTW2 CEP78 PTHR24110:SF3 CENTROSOMAL PROTEIN OF 78 KDA CENTROSOMAL PROTEIN OF 78 KDA HUMAN|HGNC=3434|UniProtKB=P18074 P18074 ERCC2 PTHR11472:SF1 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD nucleic acid binding#GO:0003676;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;damaged DNA binding#GO:0003684;DNA-dependent ATPase activity#GO:0008094;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;response to oxidative stress#GO:0006979;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;response to abiotic stimulus#GO:0009628;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;nucleotide-excision repair#GO:0006289;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleotide-excision repair, DNA incision#GO:0033683;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;response to radiation#GO:0009314;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic recombination#GO:0006312;DNA duplex unwinding#GO:0032508;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to UV#GO:0009411;biological regulation#GO:0065007;regulation of DNA recombination#GO:0000018;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA helicase#PC00011 HUMAN|HGNC=24093|UniProtKB=Q6UW32 Q6UW32 IGFL1 PTHR34827:SF2 INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 3-RELATED INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=9500|UniProtKB=O43653 O43653 PSCA PTHR16983:SF1 UPAR/LY6 DOMAIN-CONTAINING PROTEIN PROSTATE STEM CELL ANTIGEN HUMAN|HGNC=25217|UniProtKB=Q9UKZ1 Q9UKZ1 CNOT11 PTHR15975:SF0 UNCHARACTERIZED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 HUMAN|HGNC=14660|UniProtKB=Q96KS0 Q96KS0 EGLN2 PTHR12907:SF6 EGL NINE HOMOLOG-RELATED PROLYL HYDROXYLASE EGLN2 cation binding#GO:0043169;ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;dioxygenase activity#GO:0051213;metal ion binding#GO:0046872;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;response to hypoxia#GO:0001666;cellular response to chemical stimulus#GO:0070887;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;response to decreased oxygen levels#GO:0036293;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular response to hypoxia#GO:0071456;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;response to abiotic stimulus#GO:0009628;cellular protein metabolic process#GO:0044267;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;response to oxygen levels#GO:0070482 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 HUMAN|HGNC=2477|UniProtKB=P28325 P28325 CST5 PTHR46186:SF1 CYSTATIN CYSTATIN-D extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=26228|UniProtKB=Q8N6Q8 Q8N6Q8 METTL25 PTHR12496:SF0 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25 RNA methyltransferase#PC00033 HUMAN|HGNC=21735|UniProtKB=Q9UPM6 Q9UPM6 LHX6 PTHR24208:SF121 LIM/HOMEOBOX PROTEIN LHX LIM/HOMEOBOX PROTEIN LHX6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;central nervous system neuron differentiation#GO:0021953;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;forebrain development#GO:0030900;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;neuron development#GO:0048666;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=10532|UniProtKB=O75446 O75446 SAP30 PTHR13286:SF7 SAP30 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=9199|UniProtKB=P62875 P62875 POLR2L PTHR23431:SF3 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 cation binding#GO:0043169;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transition metal ion binding#GO:0046914;transferase activity, transferring phosphorus-containing groups#GO:0016772;metal ion binding#GO:0046872;ion binding#GO:0043167 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 HUMAN|HGNC=4845|UniProtKB=O60741 O60741 HCN1 PTHR45689:SF3 I[[H]] CHANNEL, ISOFORM E POTASSIUM/SODIUM HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNEL 1 ion channel#PC00133 HUMAN|HGNC=9725|UniProtKB=P06737 P06737 PYGL PTHR11468:SF26 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE, LIVER FORM transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;transferase activity, transferring glycosyl groups#GO:0016757;anion binding#GO:0043168;ion binding#GO:0043167 glucan metabolic process#GO:0044042;macromolecule catabolic process#GO:0009057;glycogen metabolic process#GO:0005977;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;cellular glucan metabolic process#GO:0006073;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 glycosyltransferase#PC00111 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717 HUMAN|HGNC=7849|UniProtKB=P15531 P15531 NME1 PTHR11349:SF69 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE A transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 HUMAN|HGNC=43734|UniProtKB=P0DPK5 P0DPK5 H3Y2 PTHR11426:SF44 HISTONE H3 HISTONE H3.X-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 histone#PC00118 DNA replication#P00017>Histones#P00527 HUMAN|HGNC=2330|UniProtKB=P23786 P23786 CPT2 PTHR22589:SF51 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=15132|UniProtKB=Q8NH74 Q8NH74 OR10A6 PTHR26453:SF692 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A6 transmembrane signal receptor#PC00197 HUMAN|HGNC=2611|UniProtKB=P20853 P20853 CYP2A7 PTHR24300:SF297 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2A7 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;monooxygenase activity#GO:0004497 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;secondary metabolic process#GO:0019748;cellular response to chemical stimulus#GO:0070887;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;response to stimulus#GO:0050896;organic cyclic compound metabolic process#GO:1901360;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 oxygenase#PC00177 Nicotine degradation#P05914>CYP2A6#P05984 HUMAN|HGNC=745|UniProtKB=P42127 P42127 ASIP PTHR16551:SF1 AGOUTI RELATED AGOUTI-SIGNALING PROTEIN neuropeptide hormone activity#GO:0005184;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 cellular aromatic compound metabolic process#GO:0006725;secondary metabolic process#GO:0019748;positive regulation of cellular metabolic process#GO:0031325;pigmentation#GO:0043473;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;pigment biosynthetic process#GO:0046148;vesicle organization#GO:0016050;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;pigment metabolic process#GO:0042440;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;secondary metabolite biosynthetic process#GO:0044550;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;melanosome organization#GO:0032438;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=27962|UniProtKB=Q86WV6 Q86WV6 STING1 PTHR34339:SF1 STIMULATOR OF INTERFERON GENES PROTEIN STIMULATOR OF INTERFERON GENES PROTEIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 response to external biotic stimulus#GO:0043207;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;endomembrane system organization#GO:0010256;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;response to biotic stimulus#GO:0009607;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;innate immune response#GO:0045087;catabolic process#GO:0009056;defense response#GO:0006952;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of macroautophagy#GO:0016241;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;defense response to other organism#GO:0098542;organelle organization#GO:0006996;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;positive regulation of autophagy#GO:0010508;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=26795|UniProtKB=Q8N8V4 Q8N8V4 ANKS4B PTHR24161:SF20 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 4B HUMAN|HGNC=12711|UniProtKB=O75436 O75436 VPS26A PTHR12233:SF4 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26A endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;cytosolic transport#GO:0016482;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=17542|UniProtKB=A6NIE9 A6NIE9 PRSS29P PTHR24256:SF441 TRYPTASE-RELATED SERINE PROTEASE 29-RELATED serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=26996|UniProtKB=P0C7I6 P0C7I6 CCDC159 PTHR34533:SF1 TRANSMEMBRANE PROTEIN CCDC163 COILED-COIL DOMAIN-CONTAINING PROTEIN 159 HUMAN|HGNC=25356|UniProtKB=Q9H040 Q9H040 SPRTN PTHR21220:SF0 UNCHARACTERIZED SPRT-LIKE DOMAIN-CONTAINING PROTEIN SPARTAN protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to DNA damage stimulus#GO:0006974;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=2063|UniProtKB=O15247 O15247 CLIC2 PTHR43920:SF4 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL PROTEIN 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ion channel#PC00133 HUMAN|HGNC=1382|UniProtKB=P35219 P35219 CA8 PTHR18952:SF104 CARBONIC ANHYDRASE CARBONIC ANHYDRASE-RELATED PROTEIN HUMAN|HGNC=9463|UniProtKB=P21108 P21108 PRPS1L1 PTHR10210:SF112 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172 HUMAN|HGNC=7125|UniProtKB=P58340 P58340 MLF1 PTHR13105:SF15 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR 1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207 HUMAN|HGNC=15131|UniProtKB=Q9H207 Q9H207 OR10A5 PTHR26453:SF148 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10A5 transmembrane signal receptor#PC00197 HUMAN|HGNC=20584|UniProtKB=Q969S0 Q969S0 SLC35B4 PTHR10778:SF4 SOLUTE CARRIER FAMILY 35 MEMBER B UDP-XYLOSE AND UDP-N-ACETYLGLUCOSAMINE TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=11187|UniProtKB=Q07889 Q07889 SOS1 PTHR23113:SF168 GUANINE NUCLEOTIDE EXCHANGE FACTOR SON OF SEVENLESS HOMOLOG 1 guanyl-nucleotide exchange factor#PC00113 PI3 kinase pathway#P00048>SOS#P01185;T cell activation#P00053>SOS#P01307;Angiogenesis#P00005>SOS-1#P00193;Integrin signalling pathway#P00034>SOS#P00920;PDGF signaling pathway#P00047>SOS#P01159;B cell activation#P00010>SOS#P00379;Ras Pathway#P04393>SOS#P04552;Interleukin signaling pathway#P00036>SOS#P00981;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Sos#P00850;CCKR signaling map#P06959>SOS1#P07061;Gonadotropin-releasing hormone receptor pathway#P06664>Sos#P06849;FGF signaling pathway#P00021>SOS#P00641;EGF receptor signaling pathway#P00018>SOS#P00558;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883 HUMAN|HGNC=9305|UniProtKB=Q00005 Q00005 PPP2R2B PTHR11871:SF1 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B BETA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629 HUMAN|HGNC=2676|UniProtKB=O43293 O43293 DAPK3 PTHR24342:SF18 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;intracellular signal transduction#GO:0035556;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=11056|UniProtKB=P48067 P48067 SLC6A9 PTHR11616:SF263 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 1 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|Ensembl=ENSG00000284844|UniProtKB=A0A2R8Y5M8 A0A2R8Y5M8 ENSG00000284844 PTHR43836:SF1 CATECHOL O-METHYLTRANSFERASE 1-RELATED CATECHOL O-METHYLTRANSFERASE 2-RELATED methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;O-methyltransferase activity#GO:0008171;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;catecholamine metabolic process#GO:0006584;cellular process#GO:0009987;organic cyclic compound metabolic process#GO:1901360;aromatic compound catabolic process#GO:0019439;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 methyltransferase#PC00155 HUMAN|HGNC=30773|UniProtKB=Q3ZLR7 Q3ZLR7 SUPT20HL1 PTHR13526:SF17 TRANSCRIPTION FACTOR SPT20 HOMOLOG TRANSCRIPTION FACTOR SPT20 HOMOLOG-LIKE 1 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=9180|UniProtKB=Q9UHN1 Q9UHN1 POLG2 PTHR10745:SF8 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 DNA POLYMERASE SUBUNIT GAMMA-2, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cellular amino acid metabolic process#GO:0006520;DNA replication#GO:0006260;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;DNA metabolic process#GO:0006259;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=24595|UniProtKB=Q8TCX1 Q8TCX1 DYNC2LI1 PTHR13236:SF0 DYNEIN 2 LIGHT INTERMEDIATE CHAIN, ISOFORM 2 CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1 dynein heavy chain binding#GO:0045504;protein binding#GO:0005515;binding#GO:0005488 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;intraciliary retrograde transport#GO:0035721;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;cytoplasmic dynein complex#GO:0005868;microtubule organizing center#GO:0005815;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=19837|UniProtKB=Q7Z5M8 Q7Z5M8 ABHD12B PTHR12277:SF69 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD12B carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;acylglycerol lipase activity#GO:0047372;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620 lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;acylglycerol catabolic process#GO:0046464;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 serine protease#PC00203 HUMAN|HGNC=10787|UniProtKB=Q13243 Q13243 SRSF5 PTHR23147:SF237 SERINE/ARGININE RICH SPLICING FACTOR SERINE/ARGININE-RICH SPLICING FACTOR 5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=15932|UniProtKB=O95925 O95925 EPPIN PTHR46751:SF2 EPPIN EPPIN negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=6055|UniProtKB=Q17R60 Q17R60 IMPG1 PTHR12199:SF3 INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN 1 extracellular matrix protein#PC00102 HUMAN|HGNC=21254|UniProtKB=B9ZVM9 B9ZVM9 TCP10L2 PTHR10331:SF25 T COMPLEX PROTEIN 10 T-COMPLEX PROTEIN 10A HOMOLOG 1-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;nitrogen compound transport#GO:0071705;centrosome duplication#GO:0051298;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;peptide transport#GO:0015833;microtubule organizing center organization#GO:0031023;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;centriole replication#GO:0007099;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=4700|UniProtKB=O15488 O15488 GYG2 PTHR11183:SF167 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN-2 transferase activity, transferring hexosyl groups#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity, transferring glycosyl groups#GO:0016757;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glucan metabolic process#GO:0044042;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;glycogen metabolic process#GO:0005977;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;glycogen biosynthetic process#GO:0005978;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;cellular glucan metabolic process#GO:0006073;polysaccharide metabolic process#GO:0005976;glucan biosynthetic process#GO:0009250;cellular carbohydrate metabolic process#GO:0044262;oxidation-reduction process#GO:0055114;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;cellular polysaccharide biosynthetic process#GO:0033692;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 glycosyltransferase#PC00111 HUMAN|HGNC=1139|UniProtKB=P78410 P78410 BTN3A2 PTHR24100:SF115 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 3 MEMBER A2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=17007|UniProtKB=O95147 O95147 DUSP14 PTHR45961:SF5 IP21249P DUAL SPECIFICITY PROTEIN PHOSPHATASE 14 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=2914|UniProtKB=P56177 P56177 DLX1 PTHR24327:SF33 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=28288|UniProtKB=Q96A25 Q96A25 TMEM106A PTHR28556:SF3 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106A HUMAN|HGNC=3058|UniProtKB=O60941 O60941 DTNB PTHR12268:SF22 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROBREVIN BETA synaptic signaling#GO:0099536;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=25537|UniProtKB=Q9NVU7 Q9NVU7 SDAD1 PTHR12730:SF1 HSDA/SDA1-RELATED PROTEIN SDA1 HOMOLOG cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;ribosome biogenesis#GO:0042254;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;peptide transport#GO:0015833;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;ribonucleoprotein complex biogenesis#GO:0022613;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9388|UniProtKB=P10644 P10644 PRKAR1A PTHR11635:SF129 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT kinase modulator#PC00140 Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;GABA-B receptor II signaling#P05731>PKA#P05752;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-r#P00700;Hedgehog signaling pathway#P00025>PKA#P00682;Endothelin signaling pathway#P00019>PKA#P00570;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059 HUMAN|HGNC=41987|UniProtKB=F8W1W9 F8W1W9 NPIPB9 PTHR15438:SF4 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER B15-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5318|UniProtKB=P24821 P24821 TNC PTHR46708:SF1 TENASCIN TENASCIN extracellular matrix protein#PC00102 HUMAN|HGNC=30282|UniProtKB=Q3MIN7 Q3MIN7 RGL3 PTHR23113:SF220 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 3 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=9647|UniProtKB=Q15678 Q15678 PTPN14 PTHR45706:SF6 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 14 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 system development#GO:0048731;circulatory system development#GO:0072359;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;vasculature development#GO:0001944;multicellular organismal process#GO:0032501;anatomical structure formation involved in morphogenesis#GO:0048646 protein phosphatase#PC00195 HUMAN|HGNC=10992|UniProtKB=P12236 P12236 SLC25A6 PTHR45635:SF13 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP/ATP TRANSLOCASE 3 carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organophosphate ester transmembrane transporter activity#GO:0015605;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;purine nucleotide transmembrane transporter activity#GO:0015216;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ATP transmembrane transporter activity#GO:0005347;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide transmembrane transporter activity#GO:0015215;active ion transmembrane transporter activity#GO:0022853 transfer/carrier protein#PC00219 HUMAN|HGNC=31978|UniProtKB=Q4V339 Q4V339 CBWD6 PTHR13748:SF31 COBW-RELATED COBW DOMAIN-CONTAINING PROTEIN 1-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9650|UniProtKB=P17706 P17706 PTPN2 PTHR46047:SF1 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 2 protein phosphatase#PC00195 HUMAN|HGNC=25932|UniProtKB=Q08AG5 Q08AG5 ZNF844 PTHR24379:SF107 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 625-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=44446|UniProtKB=D6R9N7 D6R9N7 USP17L18 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=28354|UniProtKB=Q8IZ63 Q8IZ63 PRR22 PTHR37871:SF1 PROLINE-RICH PROTEIN 22 PROLINE-RICH PROTEIN 22 HUMAN|HGNC=3378|UniProtKB=Q9H4G0 Q9H4G0 EPB41L1 PTHR23280:SF24 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Nicotine pharmacodynamics pathway#P06587>EPB41L1#P06599;Dopamine receptor mediated signaling pathway#P05912>EPB41L1#P05953;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 HUMAN|HGNC=19125|UniProtKB=Q96M96 Q96M96 FGD4 PTHR12673:SF98 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 4 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=28688|UniProtKB=Q8N4L8 Q8N4L8 CCDC24 PTHR28601:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 24 COILED-COIL DOMAIN-CONTAINING PROTEIN 24 HUMAN|HGNC=22573|UniProtKB=A8MUU1 A8MUU1 FABP5P3 PTHR11955:SF144 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN 5-LIKE PROTEIN 3-RELATED HUMAN|HGNC=1995|UniProtKB=P12532 P12532 CKMT1B PTHR11547:SF24 ARGININE OR CREATINE KINASE CREATINE KINASE U-TYPE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 amino acid kinase#PC00045 HUMAN|HGNC=26219|UniProtKB=Q9BT04 Q9BT04 FUZ PTHR13559:SF1 INTRACELLULAR TRAFFIC PROTEIN-RELATED PROTEIN FUZZY HOMOLOG vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 HUMAN|HGNC=19678|UniProtKB=Q9Y5K5 Q9Y5K5 UCHL5 PTHR10589:SF16 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 HUMAN|HGNC=29589|UniProtKB=Q6PEX7 Q6PEX7 TEX38 PTHR37362:SF1 TESTIS-EXPRESSED PROTEIN 38 TESTIS-EXPRESSED PROTEIN 38 HUMAN|HGNC=24884|UniProtKB=Q8TDS5 Q8TDS5 OXER1 PTHR46048:SF1 HYDROXYCARBOXYLIC ACID RECEPTOR 2 OXOEICOSANOID RECEPTOR 1 HUMAN|HGNC=25774|UniProtKB=Q96GX1 Q96GX1 TCTN2 PTHR14611:SF2 TECTONIC FAMILY MEMBER TECTONIC-2 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 HUMAN|HGNC=28071|UniProtKB=Q96GE5 Q96GE5 ZNF799 PTHR24379:SF5 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 799 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=2532|UniProtKB=P08311 P08311 CTSG PTHR24271:SF13 KALLIKREIN-RELATED CATHEPSIN G intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=18266|UniProtKB=Q8N8Y2 Q8N8Y2 ATP6V0D2 PTHR11028:SF2 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 pH reduction#GO:0045851;regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;vacuolar transport#GO:0007034;transport#GO:0006810;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;regulation of cellular pH#GO:0030641;vacuolar acidification#GO:0007035 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;vacuolar membrane#GO:0005774;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ATP synthase#PC00002 HUMAN|HGNC=18078|UniProtKB=O95365 O95365 ZBTB7A PTHR24394:SF14 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7A cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11455|UniProtKB=P0DMM9 P0DMM9 SULT1A3 PTHR11783:SF44 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1A3-RELATED transferase#PC00220 HUMAN|HGNC=2022|UniProtKB=P51793 P51793 CLCN4 PTHR45711:SF2 CHLORIDE CHANNEL PROTEIN H(+)/CL(-) EXCHANGE TRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;antiporter activity#GO:0015297;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;solute:cation antiporter activity#GO:0015298;gated channel activity#GO:0022836;proton transmembrane transporter activity#GO:0015078;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;solute:proton antiporter activity#GO:0015299;active ion transmembrane transporter activity#GO:0022853 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;Golgi apparatus#GO:0005794;early endosome#GO:0005769;cell junction#GO:0030054;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;intrinsic component of plasma membrane#GO:0031226;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=22999|UniProtKB=Q6UXY8 Q6UXY8 TMC5 PTHR23302:SF5 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 5 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215 HUMAN|HGNC=6065|UniProtKB=P05111 P05111 INHA PTHR11848:SF117 TGF-BETA FAMILY INHIBIN ALPHA CHAIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>Inha#P06855;BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256;TGF-beta signaling pathway#P00052>TGFbeta#P01286;Activin beta signaling pathway#P06210>activinbeta full length#P06232;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251;Activin beta signaling pathway#P06210>activin beta#P06234 HUMAN|HGNC=15811|UniProtKB=Q9NSI2 Q9NSI2 FAM207A PTHR31109:SF2 PROTEIN FAM207A PROTEIN FAM207A HUMAN|HGNC=9524|UniProtKB=Q13046 Q13046 PSG7 PTHR44427:SF19 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 7-RELATED HUMAN|HGNC=6330|UniProtKB=P43627 P43627 KIR2DL2 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=316|UniProtKB=P43652 P43652 AFM PTHR11385:SF14 SERUM ALBUMIN-RELATED AFAMIN localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 transfer/carrier protein#PC00219 HUMAN|HGNC=7606|UniProtKB=Q13402 Q13402 MYO7A PTHR13140:SF369 MYOSIN UNCONVENTIONAL MYOSIN-VIIA pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;sensory perception of sound#GO:0007605;animal organ development#GO:0048513;system process#GO:0003008;transport#GO:0006810;developmental process#GO:0032502;system development#GO:0048731;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;nervous system process#GO:0050877;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;sensory perception#GO:0007600;actin cytoskeleton organization#GO:0030036;sensory organ development#GO:0007423;vesicle cytoskeletal trafficking#GO:0099518 microvillus#GO:0005902;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;actin-based cell projection#GO:0098858;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=8982|UniProtKB=Q99570 Q99570 PIK3R4 PTHR17583:SF0 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;late endosome to vacuole transport#GO:0045324;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;establishment of protein localization#GO:0045184;phosphate-containing compound metabolic process#GO:0006796;amide transport#GO:0042886;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;cellular component disassembly#GO:0022411;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;phosphorylation#GO:0016310;protein localization to organelle#GO:0033365;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;autophagy#GO:0006914;peroxisome organization#GO:0007031 membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232;membrane#GO:0016020;phosphatidylinositol 3-kinase complex, class III#GO:0035032;vesicle#GO:0031982;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770;plasma membrane#GO:0005886 kinase modulator#PC00140 HUMAN|HGNC=26210|UniProtKB=Q32M88 Q32M88 PGGHG PTHR11051:SF8 GLYCOSYL HYDROLASE-RELATED PROTEIN-GLUCOSYLGALACTOSYLHYDROXYLYSINE GLUCOSIDASE glycosidase#PC00110 HUMAN|HGNC=20100|UniProtKB=A0A1B0GTZ2 A0A1B0GTZ2 CCDC196 PTHR37863:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 196-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 196-RELATED HUMAN|HGNC=24878|UniProtKB=Q9BVK6 Q9BVK6 TMED9 PTHR22811:SF37 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 9 vesicle targeting, to, from or within Golgi#GO:0048199;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;Golgi vesicle budding#GO:0048194;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;vesicle organization#GO:0016050;establishment of organelle localization#GO:0051656;vesicle localization#GO:0051648;Golgi organization#GO:0007030;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=15712|UniProtKB=Q9BZD3 Q9BZD3 GCOM2 PTHR23171:SF5 GDOWN1 DNA-DIRECTED RNA POLYMERASE II SUBUNIT GRINL1A-RELATED cellular localization#GO:0051641;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;signaling#GO:0023052 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nuclear envelope#GO:0005635;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;cytoplasm#GO:0005737;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;plasma membrane#GO:0005886 HUMAN|HGNC=6318|UniProtKB=O00139 O00139 KIF2A PTHR24115:SF486 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 microtubule binding motor protein#PC00156 HUMAN|HGNC=28350|UniProtKB=Q9BV97 Q9BV97 ZNF747 PTHR23232:SF100 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN ZNF747-RELATED C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25012|UniProtKB=Q3ZCW2 Q3ZCW2 LGALSL PTHR11346:SF98 GALECTIN GALECTIN-RELATED PROTEIN extracellular matrix protein#PC00102 HUMAN|HGNC=25320|UniProtKB=Q8ND61 Q8ND61 C3orf20 PTHR23093:SF20 SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 FAM194 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=6586|UniProtKB=Q9Y693 Q9Y693 LHFPL6 PTHR12489:SF12 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 6 PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=29678|UniProtKB=Q9BUK6 Q9BUK6 MSTO1 PTHR13391:SF0 MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO PROTEIN MISATO HOMOLOG 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=8671|UniProtKB=Q9Y5H7 Q9Y5H7 PCDHA5 PTHR24028:SF111 CADHERIN-87A PROTOCADHERIN ALPHA-5 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=23664|UniProtKB=Q5TCZ1 Q5TCZ1 SH3PXD2A PTHR15706:SF22 SH3 MULTIPLE DOMAIN SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A HUMAN|HGNC=5897|UniProtKB=A0A075B6K4 A0A075B6K4 IGLV3-10 PTHR23267:SF454 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-10 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=23141|UniProtKB=Q32P41 Q32P41 TRMT5 PTHR23245:SF36 TRNA METHYLTRANSFERASE TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA methyltransferase#PC00033 HUMAN|HGNC=10704|UniProtKB=O95487 O95487 SEC24B PTHR13803:SF42 SEC24-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC24B cation binding#GO:0043169;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;protein binding#GO:0005515;ion binding#GO:0043167;SNARE binding#GO:0000149 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;membrane organization#GO:0061024;Golgi vesicle budding#GO:0048194;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;endoplasmic reticulum exit site#GO:0070971;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=32389|UniProtKB=Q9BUT1 Q9BUT1 BDH2 PTHR43477:SF4 DIHYDROANTICAPSIN 7-DEHYDROGENASE 3-HYDROXYBUTYRATE DEHYDROGENASE TYPE 2 dehydrogenase#PC00092 HUMAN|HGNC=35|UniProtKB=Q8WWZ7 Q8WWZ7 ABCA5 PTHR19229:SF100 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=14379|UniProtKB=O95170 O95170 CDRT1 PTHR19872:SF7 UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN CMT1A DUPLICATED REGION TRANSCRIPT 1 PROTEIN-RELATED ubiquitin-protein ligase#PC00234 HUMAN|HGNC=26838|UniProtKB=Q495A1 Q495A1 TIGIT PTHR47734:SF1 T-CELL IMMUNORECEPTOR WITH IG AND ITIM DOMAINS PROTEIN, TIGIT T-CELL IMMUNORECEPTOR WITH IG AND ITIM DOMAINS protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of biological process#GO:0048519;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;gene expression#GO:0010467;regulation of T cell activation#GO:0050863;cytokine production#GO:0001816;leukocyte cell-cell adhesion#GO:0007159;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;negative regulation of multicellular organismal process#GO:0051241;positive regulation of metabolic process#GO:0009893;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;regulation of gene expression#GO:0010468;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;negative regulation of T cell activation#GO:0050868;lymphocyte activation#GO:0046649;macromolecule metabolic process#GO:0043170;cell-cell adhesion#GO:0098609;negative regulation of metabolic process#GO:0009892;cell adhesion#GO:0007155;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of macromolecule metabolic process#GO:0060255;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;multicellular organismal process#GO:0032501;negative regulation of lymphocyte activation#GO:0051250;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|HGNC=11115|UniProtKB=Q9BY66 Q9BY66 KDM5D PTHR10694:SF84 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5D demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=14497|UniProtKB=Q9NV31 Q9NV31 IMP3 PTHR11831:SF1 30S 40S RIBOSOMAL PROTEIN U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3 snoRNA binding#GO:0030515;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;rRNA processing#GO:0006364;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;ncRNA processing#GO:0034470;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;rRNA metabolic process#GO:0016072;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;biosynthetic process#GO:0009058;translation#GO:0006412;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;positive regulation of protein metabolic process#GO:0051247;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;90S preribosome#GO:0030686 ribosomal protein#PC00202 HUMAN|HGNC=13005|UniProtKB=O14771 O14771 ZNF213 PTHR23226:SF258 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 213 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20996|UniProtKB=Q9NVP2 Q9NVP2 ASF1B PTHR12040:SF22 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1B protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;organelle organization#GO:0006996;chromosome organization#GO:0051276;chromatin organization#GO:0006325;DNA replication-independent nucleosome organization#GO:0034724;protein-containing complex subunit organization#GO:0043933 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=10340|UniProtKB=P49207 P49207 RPL34 PTHR46595:SF6 60S RIBOSOMAL PROTEIN L34 60S RIBOSOMAL PROTEIN L34 ribosomal protein#PC00202 HUMAN|HGNC=44451|UniProtKB=D6RBM5 D6RBM5 USP17L23 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=24244|UniProtKB=Q4ZJI4 Q4ZJI4 SLC9B1 PTHR31102:SF5 FAMILY NOT NAMED SLC9B1-LIKE PROTEIN SLC9B1P1-RELATED localization#GO:0051179;cation transport#GO:0006812;monovalent inorganic cation transport#GO:0015672;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810 HUMAN|HGNC=16257|UniProtKB=Q9H4B7 Q9H4B7 TUBB1 PTHR11588:SF112 TUBULIN TUBULIN BETA-1 CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 HUMAN|HGNC=24547|UniProtKB=Q6IAN0 Q6IAN0 DHRS7B PTHR44196:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B dehydrogenase#PC00092 HUMAN|HGNC=37207|UniProtKB=A6NFX1 A6NFX1 MFSD2B PTHR11328:SF30 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 2B transporter activity#GO:0005215;lipid transporter activity#GO:0005319 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;transport#GO:0006810 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=4454|UniProtKB=Q9Y625 Q9Y625 GPC6 PTHR10822:SF31 GLYPICAN GLYPICAN-6 receptor localization to synapse#GO:0097120;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of localization#GO:0032879;regulation of synapse organization#GO:0050807;synaptic membrane adhesion#GO:0099560;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;cell junction assembly#GO:0034329;protein localization to organelle#GO:0033365;regulation of protein localization#GO:0032880;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;regulation of protein localization to membrane#GO:1905475;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;cell adhesion#GO:0007155;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular macromolecule localization#GO:0070727;synapse assembly#GO:0007416;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;regulation of nervous system development#GO:0051960;cell junction organization#GO:0034330;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;regulation of cell junction assembly#GO:1901888;regulation of synapse structure or activity#GO:0050803;cell migration#GO:0016477;locomotion#GO:0040011;protein-containing complex localization#GO:0031503 cell junction#GO:0030054;cell surface#GO:0009986;extracellular matrix#GO:0031012;synapse#GO:0045202;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=29606|UniProtKB=Q8N8V2 Q8N8V2 GBP7 PTHR10751:SF92 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 7 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830 heterotrimeric G-protein#PC00117 HUMAN|HGNC=866|UniProtKB=Q9HBG4 Q9HBG4 ATP6V0A4 PTHR11629:SF26 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE 116 KDA SUBUNIT A ISOFORM 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;binding#GO:0005488;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;enzyme binding#GO:0019899;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 pH reduction#GO:0045851;regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;regulation of cellular pH#GO:0030641;vacuolar acidification#GO:0007035 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ATP synthase#PC00002 HUMAN|HGNC=28380|UniProtKB=Q86VD7 Q86VD7 SLC25A42 PTHR24089:SF736 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A42 mitochondrial carrier protein#PC00158 HUMAN|HGNC=2876|UniProtKB=O60610 O60610 DIAPH1 PTHR45691:SF4 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 1 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 HUMAN|HGNC=16259|UniProtKB=Q8IZL2 Q8IZL2 MAML2 PTHR15692:SF9 MASTERMIND-LIKE MASTERMIND-LIKE PROTEIN 2 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 HUMAN|HGNC=9068|UniProtKB=O14939 O14939 PLD2 PTHR18896:SF121 PHOSPHOLIPASE D PHOSPHOLIPASE D2 localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;locomotion#GO:0040011 phospholipase#PC00186 Ras Pathway#P04393>PLD#P04574;Angiogenesis#P00005>PLD#P00204;Parkinson disease#P00049>PLD2#P01207 HUMAN|HGNC=14484|UniProtKB=Q13084 Q13084 MRPL28 PTHR13528:SF2 39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202 HUMAN|HGNC=15911|UniProtKB=O00567 O00567 NOP56 PTHR10894:SF0 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 56 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 small nucleolar ribonucleoprotein complex#GO:0005732;membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=3534|UniProtKB=P05160 P05160 F13B PTHR45785:SF3 COMPLEMENT FACTOR H-RELATED COAGULATION FACTOR XIII B CHAIN Vitamin D metabolism and pathway#P04396>RXR#P04602;Blood coagulation#P00011>FXIII#P00453;Blood coagulation#P00011>FXIIIa#P00419 HUMAN|HGNC=13997|UniProtKB=Q9H4Q4 Q9H4Q4 PRDM12 PTHR16515:SF20 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 12 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;developmental process#GO:0032502;gene expression#GO:0010467;cellular process#GO:0009987;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=18726|UniProtKB=Q6ZNB6 Q6ZNB6 NFXL1 PTHR12360:SF1 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 NF-X1-TYPE ZINC FINGER PROTEIN NFXL1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=17063|UniProtKB=Q15042 Q15042 RAB3GAP1 PTHR21422:SF9 RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 GTPase-activating protein#PC00257 HUMAN|HGNC=6189|UniProtKB=Q9Y219 Q9Y219 JAG2 PTHR24044:SF421 NOTCH LIGAND FAMILY MEMBER PROTEIN JAGGED-2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 Notch signaling pathway#P00045>Next#P01103;Angiogenesis#P00005>Delta/Serrate#P00226;Notch signaling pathway#P00045>Serrate#P01104 HUMAN|HGNC=29926|UniProtKB=Q9Y2X3 Q9Y2X3 NOP58 PTHR10894:SF1 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 58 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 small nucleolar ribonucleoprotein complex#GO:0005732;membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=4643|UniProtKB=O43708 O43708 GSTZ1 PTHR42673:SF4 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE transferase activity#GO:0016740;isomerase activity#GO:0016853;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound catabolic process#GO:1901565;glutathione metabolic process#GO:0006749;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;aromatic amino acid family metabolic process#GO:0009072;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;cellular amino acid metabolic process#GO:0006520;aromatic amino acid family catabolic process#GO:0009074;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 isomerase#PC00135 HUMAN|HGNC=18524|UniProtKB=Q96A47 Q96A47 ISL2 PTHR24204:SF2 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of gene expression#GO:0010468;cell part morphogenesis#GO:0032990;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;cell morphogenesis#GO:0000902;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26044|UniProtKB=Q9NWZ8 Q9NWZ8 GEMIN8 PTHR16238:SF7 GEM-ASSOCIATED PROTEIN 8 GEM-ASSOCIATED PROTEIN 8 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;intracellular#GO:0005622 HUMAN|HGNC=16634|UniProtKB=Q9Y291 Q9Y291 MRPS33 PTHR13362:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S33 28S RIBOSOMAL PROTEIN S33, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ribosomal protein#PC00202 HUMAN|HGNC=16131|UniProtKB=Q8IUB5 Q8IUB5 WFDC13 PTHR19441:SF22 WHEY ACDIC PROTEIN WAP WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 13 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antibacterial humoral response#GO:0019731;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=30249|UniProtKB=Q6ZRP7 Q6ZRP7 QSOX2 PTHR22897:SF7 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE 2 isomerase activity#GO:0016853;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;protein folding#GO:0006457 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 oxidase#PC00175 HUMAN|HGNC=12637|UniProtKB=O15550 O15550 KDM6A PTHR14017:SF9 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 6A cis-regulatory region sequence-specific DNA binding#GO:0000987;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;demethylase activity#GO:0032451;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;catalytic activity, acting on a protein#GO:0140096 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=853|UniProtKB=P15313 P15313 ATP6V1B1 PTHR43389:SF1 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B, KIDNEY ISOFORM ATP synthase#PC00002 HUMAN|HGNC=28167|UniProtKB=Q9BS34 Q9BS34 ZNF670 PTHR24377:SF944 IP01015P-RELATED ZINC FINGER PROTEIN 670 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=1937|UniProtKB=P35790 P35790 CHKA PTHR22603:SF36 CHOLINE/ETHANOALAMINE KINASE CHOLINE KINASE ALPHA kinase#PC00137 HUMAN|HGNC=9314|UniProtKB=Q08209 Q08209 PPP3CA PTHR45673:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT ALPHA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 protein phosphatase#PC00195 CCKR signaling map#P06959>CaN#P07178;T cell activation#P00053>Calcineurin#P01315;Wnt signaling pathway#P00057>Calcineurin#P01446;B cell activation#P00010>Calcineurin#P00386;Gonadotropin-releasing hormone receptor pathway#P06664>Caln#P06728 HUMAN|HGNC=22989|UniProtKB=Q8NFW1 Q8NFW1 COL22A1 PTHR24023:SF845 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=23037|UniProtKB=A8MTL9 A8MTL9 HMSD PTHR11461:SF361 SERINE PROTEASE INHIBITOR, SERPIN SERPIN-LIKE PROTEIN HMSD serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 protease inhibitor#PC00191 HUMAN|HGNC=6009|UniProtKB=P14784 P14784 IL2RB PTHR23037:SF30 CYTOKINE RECEPTOR INTERLEUKIN-2 RECEPTOR SUBUNIT BETA transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974 HUMAN|HGNC=7014|UniProtKB=P50222 P50222 MEOX2 PTHR24328:SF1 HOMEOBOX PROTEIN MOX HOMEOBOX PROTEIN MOX-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=8638|UniProtKB=Q92831 Q92831 KAT2B PTHR45750:SF2 GH11602P HISTONE ACETYLTRANSFERASE KAT2B p53 pathway#P00059>PCAF#P04629;Gonadotropin-releasing hormone receptor pathway#P06664>Pcaf#P06715 HUMAN|HGNC=9351|UniProtKB=Q9NQW5 Q9NQW5 PRDM7 PTHR16515:SF18 PR DOMAIN ZINC FINGER PROTEIN HISTONE-LYSINE N-METHYLTRANSFERASE PRDM7-RELATED regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11892|UniProtKB=P01375 P01375 TNF PTHR11471:SF23 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;tumor necrosis factor receptor superfamily binding#GO:0032813;tumor necrosis factor receptor binding#GO:0005164;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 positive regulation of gene expression#GO:0010628;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;tumor necrosis factor-mediated signaling pathway#GO:0033209;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;apoptotic signaling pathway#GO:0097190;response to tumor necrosis factor#GO:0034612;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;cell death#GO:0008219;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 Apoptosis signaling pathway#P00006>TNF#P00259;Wnt signaling pathway#P00057>NFAT Target Genes#G01559 HUMAN|HGNC=16063|UniProtKB=P55197 P55197 MLLT10 PTHR13793:SF93 PHD FINGER PROTEINS PROTEIN AF-10 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=19350|UniProtKB=Q6UW63 Q6UW63 POGLUT2 PTHR12203:SF21 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 2 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=8258|UniProtKB=Q8NGU4 Q8NGU4 OR2I1P PTHR26453:SF216 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2I1-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=4367|UniProtKB=P17900 P17900 GM2A PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR transporter activity#GO:0005215;lipid transporter activity#GO:0005319 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule localization#GO:0033036;transport#GO:0006810;glycolipid metabolic process#GO:0006664;organonitrogen compound catabolic process#GO:1901565;lipid catabolic process#GO:0016042;lipid transport#GO:0006869;sphingolipid metabolic process#GO:0006665;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;localization#GO:0051179;membrane lipid metabolic process#GO:0006643;cellular lipid metabolic process#GO:0044255;cellular amide metabolic process#GO:0043603 leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 HUMAN|HGNC=19311|UniProtKB=Q8IXF0 Q8IXF0 NPAS3 PTHR23043:SF30 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=6517|UniProtKB=P18428 P18428 LBP PTHR10504:SF66 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED LIPOPOLYSACCHARIDE-BINDING PROTEIN carbohydrate derivative binding#GO:0097367;lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;binding#GO:0005488 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;positive regulation of cytokine production#GO:0001819;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;defense response to Gram-positive bacterium#GO:0050830;cell activation involved in immune response#GO:0002263;response to lipopolysaccharide#GO:0032496;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;defense response to Gram-negative bacterium#GO:0050829;response to stress#GO:0006950;leukocyte activation involved in immune response#GO:0002366;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;regulation of cytokine biosynthetic process#GO:0042035;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;tumor necrosis factor production#GO:0032640;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;biosynthetic process#GO:0009058;cytokine production#GO:0001816;cellular response to lipid#GO:0071396;inflammatory response#GO:0006954;positive regulation of biosynthetic process#GO:0009891;cellular response to oxygen-containing compound#GO:1901701;positive regulation of metabolic process#GO:0009893;response to bacterium#GO:0009617;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of immune system process#GO:0002682;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;defense response to bacterium#GO:0042742;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of leukocyte activation#GO:0002694;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=14864|UniProtKB=P25940 P25940 COL5A3 PTHR24023:SF1023 COLLAGEN ALPHA COLLAGEN ALPHA-3(V) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=255|UniProtKB=P28332 P28332 ADH6 PTHR43880:SF20 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE 6 cation binding#GO:0043169;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 response to organic substance#GO:0010033;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=3079|UniProtKB=O43812 O43812 DUX1 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=23082|UniProtKB=Q6NTF9 Q6NTF9 RHBDD2 PTHR11009:SF31 DER1-LIKE PROTEIN, DERLIN RHOMBOID DOMAIN-CONTAINING PROTEIN 2 enzyme binding#GO:0019899;protein binding#GO:0005515;protease binding#GO:0002020;binding#GO:0005488 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;ubiquitin-dependent ERAD pathway#GO:0030433;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane protein complex#GO:0098796;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=11795|UniProtKB=P40225 P40225 THPO PTHR10560:SF0 THROMBOPOIETIN THROMBOPOIETIN HUMAN|HGNC=20273|UniProtKB=Q9Y3B6 Q9Y3B6 EMC9 PTHR12941:SF12 ER MEMBRANE PROTEIN COMPLEX ER MEMBRANE PROTEIN COMPLEX SUBUNIT 9 membrane protein complex#GO:0098796;ER membrane protein complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=3437|UniProtKB=P28715 P28715 ERCC5 PTHR16171:SF9 DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED BASIC IMMUNOGLOBULIN-LIKE VARIABLE MOTIF-CONTAINING PROTEIN-RELATED DNA metabolism protein#PC00009 HUMAN|HGNC=33847|UniProtKB=A6NJ69 A6NJ69 IGIP PTHR39224:SF1 IGA-INDUCING PROTEIN HOMOLOG IGA-INDUCING PROTEIN HOMOLOG HUMAN|HGNC=25001|UniProtKB=Q8NCP5 Q8NCP5 ZBTB44 PTHR24383:SF10 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=14940|UniProtKB=Q8WVI7 Q8WVI7 PPP1R1C PTHR15417:SF5 PROTEIN PHOSPHATASE INHIBITOR AND DOPAMINE- AND CAMP-REGULATED NEURONAL PHOSPHOPROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1C regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phosphatase inhibitor#PC00183 HUMAN|HGNC=6136|UniProtKB=Q9UKX5 Q9UKX5 ITGA11 PTHR23220:SF21 INTEGRIN ALPHA INTEGRIN ALPHA-11 integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=17178|UniProtKB=P59510 P59510 ADAMTS20 PTHR13723:SF165 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 20 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=29182|UniProtKB=Q9UPV0 Q9UPV0 CEP164 PTHR18902:SF27 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED CENTROSOMAL PROTEIN OF 164 KDA endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;protein targeting to lysosome#GO:0006622;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;regulation of protein transport#GO:0051223;regulation of protein localization#GO:0032880;establishment of protein localization to vacuole#GO:0072666;Golgi organization#GO:0007030;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;regulation of cellular localization#GO:0060341;microtubule organizing center organization#GO:0031023;cytosolic transport#GO:0016482;protein localization#GO:0008104;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;Golgi apparatus#GO:0005794;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=12294|UniProtKB=A0A0C4DH27 A0A0C4DH27 TRGV8 PTHR19256:SF54 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 8 HUMAN|HGNC=18282|UniProtKB=Q96KB5 Q96KB5 PBK PTHR43289:SF14 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE-RELATED non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=24905|UniProtKB=Q9NS37 Q9NS37 CREBZF PTHR14312:SF1 CREB/ATF BZIP TRANSCRIPTION FACTOR CREB/ATF BZIP TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=26378|UniProtKB=Q8N7C3 Q8N7C3 TRIML2 PTHR24103:SF561 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIML2-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=4511|UniProtKB=Q9Y2T6 Q9Y2T6 GPR55 PTHR24232:SF56 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 55 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=19972|UniProtKB=Q96JQ2 Q96JQ2 CLMN PTHR47535:SF7 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G CALMIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 localization#GO:0051179;nuclear migration#GO:0007097;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of organelle localization#GO:0051656;nucleus localization#GO:0051647 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;organelle outer membrane#GO:0031968;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;plasma membrane#GO:0005886 HUMAN|HGNC=4513|UniProtKB=Q9P1P4 Q9P1P4 TAAR3P PTHR24249:SF82 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 3-RELATED G protein-coupled amine receptor activity#GO:0008227;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=28513|UniProtKB=Q8IYS2 Q8IYS2 KIAA2013 PTHR31386:SF2 UNCHARACTERIZED PROTEIN KIAA2013 SIMILAR TO RIKEN CDNA 2510039O18 HUMAN|HGNC=19440|UniProtKB=Q9Y3A5 Q9Y3A5 SBDS PTHR10927:SF1 RIBOSOME MATURATION PROTEIN SBDS RIBOSOME MATURATION PROTEIN SBDS RNA metabolism protein#PC00031 HUMAN|HGNC=15478|UniProtKB=Q9BZ11 Q9BZ11 ADAM33 PTHR11905:SF38 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 33 metalloprotease#PC00153 HUMAN|HGNC=18167|UniProtKB=Q9NZW5 Q9NZW5 MPP6 PTHR23122:SF45 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MAGUK P55 SUBFAMILY MEMBER 6 scaffold/adaptor protein#PC00226 HUMAN|HGNC=12926|UniProtKB=Q15928 Q15928 ZNF141 PTHR24384:SF102 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 141 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=29416|UniProtKB=Q5T7W0 Q5T7W0 ZNF618 PTHR24383:SF12 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 618 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28727|UniProtKB=Q9BUR5 Q9BUR5 APOO PTHR14564:SF2 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT MIC26 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cristae formation#GO:0042407;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=12572|UniProtKB=P13051 P13051 UNG PTHR11264:SF0 URACIL-DNA GLYCOSYLASE URACIL-DNA GLYCOSYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA glycosylase#PC00010 HUMAN|HGNC=8885|UniProtKB=P0DJD8 P0DJD8 PGA3 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED HUMAN|HGNC=31416|UniProtKB=Q86Z23 Q86Z23 C1QL4 PTHR22923:SF67 CEREBELLIN-RELATED COMPLEMENT C1Q-LIKE PROTEIN 4 HUMAN|HGNC=30375|UniProtKB=Q9NR16 Q9NR16 CD163L1 PTHR19331:SF463 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160 serine protease#PC00203 HUMAN|HGNC=1748|UniProtKB=P12830 P12830 CDH1 PTHR24027:SF435 CADHERIN-23 CADHERIN-1 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 CCKR signaling map#P06959>E-cadherin#G06981;Alzheimer disease-presenilin pathway#P00004>E-cadherin transmembrane fragment#P00139;Alzheimer disease-presenilin pathway#P00004>E-cadherin C-terminal fragment#P00117;Wnt signaling pathway#P00057>Cadherin#P01440;Alzheimer disease-presenilin pathway#P00004>E-cadherin N-terminal fragment#P00165;Alzheimer disease-presenilin pathway#P00004>E-cadherin intracellular fragment#P00168;Cadherin signaling pathway#P00012>Cadherin#P00471;CCKR signaling map#P06959>E-cadherin#P07171;CCKR signaling map#P06959>E-cadherin#G07274;Alzheimer disease-presenilin pathway#P00004>E-cadherin#P00118 HUMAN|HGNC=11220|UniProtKB=Q14515 Q14515 SPARCL1 PTHR13866:SF16 SPARC OSTEONECTIN SPARC-LIKE PROTEIN 1 cation binding#GO:0043169;extracellular matrix binding#GO:0050840;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=17079|UniProtKB=Q9NZ52 Q9NZ52 GGA3 PTHR45905:SF3 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA3 HUMAN|HGNC=18216|UniProtKB=Q8WXS4 Q8WXS4 TMEM37 PTHR31767:SF0 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-LIKE SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-LIKE SUBUNIT voltage-gated ion channel#PC00241 HUMAN|HGNC=2389|UniProtKB=P02511 P02511 CRYAB PTHR45640:SF5 HEAT SHOCK PROTEIN HSP-12.2-RELATED ALPHA-CRYSTALLIN B CHAIN VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 HUMAN|HGNC=28687|UniProtKB=Q6UX73 Q6UX73 C16orf89 PTHR33539:SF1 UPF0764 PROTEIN C16ORF89 UPF0764 PROTEIN C16ORF89 HUMAN|HGNC=26413|UniProtKB=Q86V42 Q86V42 FAM124A PTHR14715:SF4 FAMILY NOT NAMED PROTEIN FAM124A HUMAN|HGNC=28624|UniProtKB=Q8N1E6 Q8N1E6 FBXL14 PTHR13318:SF198 UNCHARACTERIZED F-BOX/LRR-REPEAT PROTEIN 14 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=17170|UniProtKB=O95900 O95900 TRUB2 PTHR13195:SF0 PSEUDOURIDINE SYNTHASE-RELATED MITOCHONDRIAL MRNA PSEUDOURIDINE SYNTHASE TRUB2 lyase#PC00144 HUMAN|HGNC=3020|UniProtKB=P21728 P21728 DRD1 PTHR24248:SF139 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR D(1A) DOPAMINE RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular transducer activity#GO:0060089;ion binding#GO:0043167;neurotransmitter receptor activity#GO:0030594;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;dopamine receptor signaling pathway#GO:0007212;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948 HUMAN|HGNC=26709|UniProtKB=Q8N9R8 Q8N9R8 SCAI PTHR21243:SF15 PROTEIN SCAI PROTEIN SCAI transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=30990|UniProtKB=Q8NEG5 Q8NEG5 ZSWIM2 PTHR21540:SF3 RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2 E3 UBIQUITIN-PROTEIN LIGASE ZSWIM2 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=19919|UniProtKB=Q8NCR6 Q8NCR6 SMRP1 PTHR35664:SF1 SPERMATID-SPECIFIC MANCHETTE-RELATED PROTEIN 1 SPERMATID-SPECIFIC MANCHETTE-RELATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;perinuclear region of cytoplasm#GO:0048471;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=10294|UniProtKB=Q16518 Q16518 RPE65 PTHR10543:SF57 BETA-CAROTENE DIOXYGENASE RETINOID ISOMEROHYDROLASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;hydrolase activity#GO:0016787;isomerase activity#GO:0016853;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;pigment biosynthetic process#GO:0046148;catabolic process#GO:0009056;carotenoid biosynthetic process#GO:0016117;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 oxygenase#PC00177 HUMAN|HGNC=29129|UniProtKB=O94919 O94919 ENDOD1 PTHR21472:SF8 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN ENDOD1 ENDONUCLEASE DOMAIN-CONTAINING 1 PROTEIN HUMAN|HGNC=1570|UniProtKB=P32238 P32238 CCKAR PTHR24241:SF120 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CHOLECYSTOKININ RECEPTOR TYPE A signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cell communication#GO:0007154;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;hormone secretion#GO:0046879;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;regulation of secretion#GO:0051046;secretion#GO:0046903;regulation of hormone secretion#GO:0046883;biological regulation#GO:0065007;signal release#GO:0023061;G protein-coupled receptor signaling pathway#GO:0007186;hormone transport#GO:0009914;cell-cell signaling#GO:0007267;signaling#GO:0023052;export from cell#GO:0140352;secretion by cell#GO:0032940 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=33391|UniProtKB=Q5R3K3 Q5R3K3 CALHM6 PTHR32261:SF4 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 6 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=1706|UniProtKB=P01732 P01732 CD8A PTHR10441:SF2 CD8 ALPHA CHAIN T-CELL SURFACE GLYCOPROTEIN CD8 ALPHA CHAIN HUMAN|HGNC=14969|UniProtKB=Q9Y5X3 Q9Y5X3 SNX5 PTHR45850:SF5 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-5 cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=4315|UniProtKB=Q53GS7 Q53GS7 GLE1 PTHR12960:SF0 GLE-1-RELATED NUCLEOPORIN GLE1 translation initiation factor binding#GO:0031369;small molecule binding#GO:0036094;binding#GO:0005488;protein binding#GO:0005515;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543 posttranscriptional regulation of gene expression#GO:0010608;cellular localization#GO:0051641;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of translational initiation#GO:0006446;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;nuclear transport#GO:0051169;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-containing complex disassembly#GO:0032984;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;regulation of cellular process#GO:0050794;protein transport#GO:0015031;regulation of translation#GO:0006417;intracellular transport#GO:0046907;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;protein-containing complex localization#GO:0031503;regulation of cellular metabolic process#GO:0031323;cellular protein complex disassembly#GO:0043624;macromolecule localization#GO:0033036;peptide metabolic process#GO:0006518;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nucleic acid transport#GO:0050657;biosynthetic process#GO:0009058;ribonucleoprotein complex export from nucleus#GO:0071426;translation#GO:0006412;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;translational termination#GO:0006415;cellular component disassembly#GO:0022411;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;protein export from nucleus#GO:0006611;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;ribonucleoprotein complex localization#GO:0071166;mRNA transport#GO:0051028;cellular process#GO:0009987;localization#GO:0051179;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;translational initiation#GO:0006413;intracellular protein transport#GO:0006886;RNA export from nucleus#GO:0006405;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 translation factor#PC00223 HUMAN|HGNC=30697|UniProtKB=Q8TB96 Q8TB96 ITFG1 PTHR13412:SF0 T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG T-CELL IMMUNOMODULATORY PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=9377|UniProtKB=P54646 P54646 PRKAA2 PTHR24343:SF303 SERINE/THREONINE KINASE 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 p53 pathway by glucose deprivation#P04397>AMPK#P04639 HUMAN|HGNC=7113|UniProtKB=Q9H000 Q9H000 MKRN2 PTHR11224:SF17 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-2-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=2986|UniProtKB=Q14184 Q14184 DOC2B PTHR45729:SF9 RABPHILIN, ISOFORM A DOUBLE C2-LIKE DOMAIN-CONTAINING PROTEIN BETA HUMAN|HGNC=25601|UniProtKB=Q9HAD4 Q9HAD4 WDR41 PTHR22805:SF2 WDR41-RELATED WD REPEAT-CONTAINING PROTEIN 41 HUMAN|HGNC=18619|UniProtKB=Q96JB2 Q96JB2 COG3 PTHR13302:SF8 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;organelle organization#GO:0006996;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=15739|UniProtKB=O75901 O75901 RASSF9 PTHR15286:SF10 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 9 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3621|UniProtKB=P55899 P55899 FCGRT PTHR16675:SF3 MHC CLASS I-RELATED IGG RECEPTOR FCRN LARGE SUBUNIT P51 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=21029|UniProtKB=Q7Z4V0 Q7Z4V0 ZNF438 PTHR24393:SF109 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 438 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=283|UniProtKB=P18825 P18825 ADRA2C PTHR24248:SF25 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-2C ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 HUMAN|HGNC=16672|UniProtKB=P50579 P50579 METAP2 PTHR45777:SF2 METHIONINE AMINOPEPTIDASE 2 METHIONINE AMINOPEPTIDASE 2 protease#PC00190 HUMAN|HGNC=33196|UniProtKB=Q00G26 Q00G26 PLIN5 PTHR14024:SF9 PERILIPIN PERILIPIN-5 localization#GO:0051179;regulation of biological process#GO:0050789;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;maintenance of location#GO:0051235;biological regulation#GO:0065007;regulation of localization#GO:0032879;lipid localization#GO:0010876;lipid storage#GO:0019915;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=37180|UniProtKB=P0C7H9 P0C7H9 USP17L7 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=26217|UniProtKB=Q5U3C3 Q5U3C3 TMEM164 PTHR20948:SF2 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 164 HUMAN|HGNC=7544|UniProtKB=Q96S97 Q96S97 MYADM PTHR17068:SF3 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER HUMAN|HGNC=27018|UniProtKB=Q8NI32 Q8NI32 LYPD6B PTHR31171:SF3 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 6 LY6/PLAUR DOMAIN-CONTAINING PROTEIN 6B cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;receptor regulator activity#GO:0030545;acetylcholine receptor activity#GO:0015464;molecular function regulator#GO:0098772;molecular transducer activity#GO:0060089;acetylcholine receptor regulator activity#GO:0030548;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;acetylcholine binding#GO:0042166;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 HUMAN|HGNC=18912|UniProtKB=A8MXZ3 A8MXZ3 KRTAP9-1 PTHR23262:SF221 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-1 HUMAN|HGNC=3609|UniProtKB=P12319 P12319 FCER1A PTHR11481:SF12 IMMUNOGLOBULIN FC RECEPTOR HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=17422|UniProtKB=Q9NPF2 Q9NPF2 CHST11 PTHR12137:SF32 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 11 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=14325|UniProtKB=Q9BXJ5 Q9BXJ5 C1QTNF2 PTHR15427:SF28 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 2 HUMAN|HGNC=11605|UniProtKB=O95947 O95947 TBX6 PTHR11267:SF100 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 specification of symmetry#GO:0009799;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;heart looping#GO:0001947;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;heart development#GO:0007507;embryonic heart tube development#GO:0035050;determination of heart left/right asymmetry#GO:0061371;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;determination of bilateral symmetry#GO:0009855;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;determination of left/right symmetry#GO:0007368;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=27006|UniProtKB=Q5TF58 Q5TF58 IFFO2 PTHR14516:SF1 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER INTERMEDIATE FILAMENT FAMILY ORPHAN 2 dehydrogenase#PC00092 HUMAN|HGNC=30139|UniProtKB=O60299 O60299 LZTS3 PTHR19354:SF6 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 3-RELATED regulation of cell morphogenesis involved in differentiation#GO:0010769;regulation of dendrite morphogenesis#GO:0048814;regulation of dendrite development#GO:0050773;neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of anatomical structure morphogenesis#GO:0022603;dendrite development#GO:0016358;developmental process#GO:0032502;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;dendritic spine organization#GO:0097061;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;cell morphogenesis involved in differentiation#GO:0000904;regulation of dendritic spine development#GO:0060998;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of neuron differentiation#GO:0045664;dendrite morphogenesis#GO:0048813;cellular component morphogenesis#GO:0032989;regulation of neuron projection development#GO:0010975;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;regulation of synapse structure or activity#GO:0050803;generation of neurons#GO:0048699 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 HUMAN|HGNC=815|UniProtKB=Q01814 Q01814 ATP2B2 PTHR24093:SF377 CATION TRANSPORTING ATPASE PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 2 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;binding#GO:0005488;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;integral component of plasma membrane#GO:0005887;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=14013|UniProtKB=Q9NTJ3 Q9NTJ3 SMC4 PTHR43939:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 158 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 4 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic chromosome condensation#GO:0007076;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=14152|UniProtKB=Q9BQD7 Q9BQD7 ANTKMT PTHR13610:SF5 UNCHARACTERIZED ADENINE NUCLEOTIDE TRANSLOCASE LYSINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;purine nucleotide biosynthetic process#GO:0006164;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;nucleobase-containing compound metabolic process#GO:0006139;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;ribose phosphate metabolic process#GO:0019693;positive regulation of transmembrane transport#GO:0034764;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;cellular protein metabolic process#GO:0044267;purine nucleotide metabolic process#GO:0006163;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;regulation of ion transmembrane transport#GO:0034765;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of phosphorylation#GO:0042325;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;cation transport#GO:0006812;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;protein metabolic process#GO:0019538;heterocycle metabolic process#GO:0046483;peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;transmembrane transport#GO:0055085;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;positive regulation of ion transmembrane transporter activity#GO:0032414;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;mitochondrial transport#GO:0006839;ATP synthesis coupled proton transport#GO:0015986;positive regulation of transporter activity#GO:0032411;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of ion transmembrane transport#GO:0034767;oxidative phosphorylation#GO:0006119;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleoside triphosphate metabolic process#GO:0009199;cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;inorganic cation transmembrane transport#GO:0098662;positive regulation of cellular metabolic process#GO:0031325;inorganic ion transmembrane transport#GO:0098660;nucleotide biosynthetic process#GO:0009165;regulation of phosphorus metabolic process#GO:0051174;protein alkylation#GO:0008213;protein methylation#GO:0006479;establishment of localization#GO:0051234;ATP metabolic process#GO:0046034;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;mitochondrial transmembrane transport#GO:1990542;positive regulation of biological process#GO:0048518;purine nucleoside triphosphate biosynthetic process#GO:0009145;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;positive regulation of transport#GO:0051050;ribonucleoside triphosphate biosynthetic process#GO:0009201;regulation of cellular localization#GO:0060341;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;ribonucleotide biosynthetic process#GO:0009260;macromolecule methylation#GO:0043414;positive regulation of phosphate metabolic process#GO:0045937;regulation of ion transport#GO:0043269;aromatic compound biosynthetic process#GO:0019438;peptidyl-lysine trimethylation#GO:0018023;intracellular transport#GO:0046907;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of ion transport#GO:0043270;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;transport#GO:0006810;peptidyl-amino acid modification#GO:0018193;purine-containing compound biosynthetic process#GO:0072522;cation transmembrane transport#GO:0098655;positive regulation of metabolic process#GO:0009893;regulation of transport#GO:0051049;phosphorylation#GO:0016310;metabolic process#GO:0008152;monovalent inorganic cation transport#GO:0015672;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;methylation#GO:0032259;regulation of cellular biosynthetic process#GO:0031326;biological regulation#GO:0065007;energy coupled proton transport, down electrochemical gradient#GO:0015985;establishment of localization in cell#GO:0051649;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11566|UniProtKB=O15533 O15533 TAPBP PTHR23411:SF22 TAPASIN TAPASIN immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=28999|UniProtKB=Q92567 Q92567 FAM168A PTHR31844:SF1 MYELIN-ASSOCIATED NEURITE-OUTGROWTH INHIBITOR-RELATED PROTEIN FAM168A DNA repair#GO:0006281;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of DNA repair#GO:0045739;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;positive regulation of cellular metabolic process#GO:0031325;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of DNA repair#GO:0006282;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of cellular response to stress#GO:0080135;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 myelin protein#PC00161 HUMAN|HGNC=17907|UniProtKB=Q8IUF1 Q8IUF1 CBWD2 PTHR13748:SF31 COBW-RELATED COBW DOMAIN-CONTAINING PROTEIN 1-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=28667|UniProtKB=Q9BW04 Q9BW04 SARG PTHR21555:SF0 SPECIFICALLY ANDROGEN-REGULATED GENE PROTEIN SPECIFICALLY ANDROGEN-REGULATED GENE PROTEIN HUMAN|HGNC=30836|UniProtKB=Q8TC44 Q8TC44 POC1B PTHR44019:SF1 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG B HUMAN|HGNC=5560|UniProtKB=P0DTW3 P0DTW3 IGHV1-38-4 PTHR23266:SF297 IMMUNOGLOBULIN HEAVY CHAIN NON-FUNCTIONAL IMMUNOGLOBULIN HEAVY VARIABLE 1-38-4-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=15502|UniProtKB=Q96BZ8 Q96BZ8 LENG1 PTHR22093:SF0 LEUKOCYTE RECEPTOR CLUSTER LRC MEMBER 1 LEUKOCYTE RECEPTOR CLUSTER MEMBER 1 HUMAN|HGNC=11804|UniProtKB=Q01085 Q01085 TIAL1 PTHR10352:SF11 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G NUCLEOLYSIN TIAR translation initiation factor#PC00224 HUMAN|HGNC=11802|UniProtKB=P31483 P31483 TIA1 PTHR10352:SF10 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G NUCLEOLYSIN TIA-1 ISOFORM P40 translation initiation factor#PC00224 HUMAN|HGNC=29364|UniProtKB=Q9C0D5 Q9C0D5 TANC1 PTHR24166:SF23 ROLLING PEBBLES, ISOFORM B PROTEIN TANC1 HUMAN|HGNC=6018|UniProtKB=P05231 P05231 IL6 PTHR10511:SF3 GRANULOCYTE COLONY-STIMULATING FACTOR INTERLEUKIN-6 Interleukin signaling pathway#P00036>Interleukin#P00970;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 HUMAN|HGNC=20444|UniProtKB=Q9P267 Q9P267 MBD5 PTHR16112:SF18 METHYL-CPG BINDING PROTEIN, DROSOPHILA METHYL-CPG-BINDING DOMAIN PROTEIN 5 chromatin binding#GO:0003682;binding#GO:0005488 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=51333|UniProtKB=P0DMR1 P0DMR1 HNRNPCL4 PTHR13968:SF30 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN C-LIKE 3-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=1935|UniProtKB=Q9UKJ5 Q9UKJ5 CHIC2 PTHR13005:SF3 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN CYSTEINE-RICH HYDROPHOBIC DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=26258|UniProtKB=Q8WWF1 Q8WWF1 C1orf54 PTHR37870:SF1 CHROMOSOME 1 OPEN READING FRAME 54 CHROMOSOME 1 OPEN READING FRAME 54 HUMAN|HGNC=8622|UniProtKB=Q06710 Q06710 PAX8 PTHR45636:SF6 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX PROTEIN PAX-8 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=23786|UniProtKB=Q8TBX8 Q8TBX8 PIP4K2C PTHR23086:SF35 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 GAMMA kinase#PC00137 HUMAN|HGNC=18874|UniProtKB=O43561 O43561 LAT PTHR15586:SF0 LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 1 LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 1 T cell activation#P00053>LAT#P01325 HUMAN|HGNC=13930|UniProtKB=Q8TD31 Q8TD31 CCHCR1 PTHR46822:SF1 COILED-COIL ALPHA-HELICAL ROD PROTEIN 1 COILED-COIL ALPHA-HELICAL ROD PROTEIN 1 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;nuclear transport#GO:0051169 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7657|UniProtKB=O15394 O15394 NCAM2 PTHR12231:SF231 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN NEURAL CELL ADHESION MOLECULE 2 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=6971|UniProtKB=P40926 P40926 MDH2 PTHR11540:SF16 MALATE AND LACTATE DEHYDROGENASE MALATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 Pyruvate metabolism#P02772>Lactate Dehydrogenase#P03139 HUMAN|HGNC=18578|UniProtKB=Q9NUQ3 Q9NUQ3 TXLNG PTHR16127:SF14 TAXILIN GAMMA-TAXILIN biological regulation#GO:0065007;regulation of biological process#GO:0050789;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;cellular process#GO:0009987;regulation of cellular process#GO:0050794 membrane traffic protein#PC00150 HUMAN|HGNC=13579|UniProtKB=Q9Y5B6 Q9Y5B6 PAXBP1 PTHR12214:SF2 GC-RICH SEQUENCE DNA-BINDING FACTOR PAX3- AND PAX7-BINDING PROTEIN 1 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|Ensembl=ENSG00000274764|UniProtKB=A3QJZ7 A3QJZ7 PRAMEF27 PTHR14224:SF100 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 11-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=7176|UniProtKB=P14780 P14780 MMP9 PTHR10201:SF30 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-9 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 CCKR signaling map#P06959>MMP9#G07288;CCKR signaling map#P06959>MMP9#G06994;Plasminogen activating cascade#P00050>pro-MMP-9#P01259;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=29941|UniProtKB=Q8WUU5 Q8WUU5 GATAD1 PTHR13340:SF2 GATA ZINC FINGER DOMAIN-CONTAINING GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;chromosome organization#GO:0051276 zinc finger transcription factor#PC00244 HUMAN|HGNC=11005|UniProtKB=P11166 P11166 SLC2A1 PTHR23503:SF51 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1 Gonadotropin-releasing hormone receptor pathway#P06664>Glut1#G06890;Gonadotropin-releasing hormone receptor pathway#P06664>Glut1#P06724;Gonadotropin-releasing hormone receptor pathway#P06664>Glut1#G06675 HUMAN|HGNC=22995|UniProtKB=Q7Z5M5 Q7Z5M5 TMC3 PTHR23302:SF35 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215 HUMAN|HGNC=8941|UniProtKB=P01009 P01009 SERPINA1 PTHR11461:SF165 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-1-ANTITRYPSIN serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>alpha1-antitrypsin#P00421 HUMAN|HGNC=5298|UniProtKB=O95264 O95264 HTR3B PTHR18945:SF53 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 5HT3 type receptor mediated signaling pathway#P04375>5HT3 Rec#P04422 HUMAN|HGNC=20589|UniProtKB=Q9P0J7 Q9P0J7 KCMF1 PTHR12268:SF13 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 synaptic signaling#GO:0099536;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=12502|UniProtKB=P63165 P63165 SUMO1 PTHR10562:SF117 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;PML body#GO:0016605 p53 pathway#P00059>Sumo-1 ligase#P04635 HUMAN|HGNC=21270|UniProtKB=Q9BQ67 Q9BQ67 GRWD1 PTHR45903:SF1 GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1 GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1 HUMAN|HGNC=28072|UniProtKB=Q5U5X0 Q5U5X0 LYRM7 PTHR46749:SF1 COMPLEX III ASSEMBLY FACTOR LYRM7 COMPLEX III ASSEMBLY FACTOR LYRM7 chaperone#PC00072 HUMAN|HGNC=7824|UniProtKB=Q92982 Q92982 NINJ1 PTHR12316:SF19 NINJURIN-RELATED NINJURIN-1 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell adhesion molecule#PC00069 HUMAN|HGNC=16734|UniProtKB=Q86XN8 Q86XN8 MEX3D PTHR23285:SF3 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING PROTEIN MEX3D RNA metabolism protein#PC00031 HUMAN|HGNC=29369|UniProtKB=Q9C0B0 Q9C0B0 UNK PTHR14493:SF36 UNKEMPT FAMILY MEMBER RING FINGER PROTEIN UNKEMPT HOMOLOG nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699 HUMAN|HGNC=15879|UniProtKB=Q8WYA6 Q8WYA6 CTNNBL1 PTHR14978:SF4 BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN BETA-CATENIN-LIKE PROTEIN 1 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=1571|UniProtKB=P32239 P32239 CCKBR PTHR24243:SF45 G-PROTEIN COUPLED RECEPTOR GASTRIN/CHOLECYSTOKININ TYPE B RECEPTOR G-protein coupled receptor#PC00021 CCKR signaling map#P06959>CCK2R#P07042 HUMAN|HGNC=28002|UniProtKB=Q495B1 Q495B1 ANKDD1A PTHR24125:SF0 ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1A HUMAN|HGNC=20790|UniProtKB=Q9Y4P1 Q9Y4P1 ATG4B PTHR22624:SF39 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4B cysteine protease#PC00081 HUMAN|HGNC=16229|UniProtKB=Q9GZP1 Q9GZP1 NRSN2 PTHR14796:SF5 NEURENSIN 1-RELATED NEURENSIN-2 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 somatodendritic compartment#GO:0036477;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;neuronal cell body#GO:0043025;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell body#GO:0044297;neuron projection#GO:0043005;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;transport vesicle#GO:0030133;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=24614|UniProtKB=P57772 P57772 EEFSEC PTHR43721:SF11 ELONGATION FACTOR TU-RELATED SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 translation elongation factor#PC00222 HUMAN|HGNC=12010|UniProtKB=P09493 P09493 TPM1 PTHR19269:SF41 TROPOMYOSIN TROPOMYOSIN ALPHA-1 CHAIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 blood circulation#GO:0008015;system process#GO:0003008;heart contraction#GO:0060047;cardiac muscle contraction#GO:0060048;cellular component organization#GO:0016043;cellular process#GO:0009987;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;heart process#GO:0003015;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 HUMAN|HGNC=29605|UniProtKB=Q9UQQ2 Q9UQQ2 SH2B3 PTHR10872:SF1 SH2B ADAPTER PROTEIN SH2B ADAPTER PROTEIN 3 molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=53904|UniProtKB=A0A2R8YFL7 A0A2R8YFL7 OOSP4A PTHR14380:SF11 PLACENTA-SPECIFIC PROTEIN 1 OOCYTE-SECRETED PROTEIN 4A HUMAN|HGNC=5176|UniProtKB=Q13601 Q13601 KRR1 PTHR12581:SF0 HIV-1 REV BINDING PROTEIN 2, 3 KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=11345|UniProtKB=O95980 O95980 RECK PTHR13487:SF3 SERINE PROTEASE INHIBITOR REVERSION-INDUCING CYSTEINE-RICH PROTEIN WITH KAZAL MOTIFS peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;extracellular structure organization#GO:0043062;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 protease inhibitor#PC00191 HUMAN|HGNC=1512|UniProtKB=P31415 P31415 CASQ1 PTHR10033:SF14 CALSEQUESTRIN CALSEQUESTRIN-1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;regulation of muscle contraction#GO:0006937;calcium-mediated signaling#GO:0019722;divalent inorganic cation homeostasis#GO:0072507;regulation of metal ion transport#GO:0010959;system process#GO:0003008;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;skeletal muscle contraction#GO:0003009;divalent inorganic cation transport#GO:0072511;intracellular signal transduction#GO:0035556;cellular cation homeostasis#GO:0030003;regulation of transmembrane transport#GO:0034762;regulation of multicellular organismal process#GO:0051239;calcium ion transmembrane transport#GO:0070588;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of calcium ion transport#GO:0051924;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cellular localization#GO:0060341;regulation of cytosolic calcium ion concentration#GO:0051480;ion transmembrane transport#GO:0034220;striated muscle contraction#GO:0006941;cellular ion homeostasis#GO:0006873;calcium ion transport into cytosol#GO:0060402;regulation of ion transmembrane transport#GO:0034765;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;calcium ion transmembrane import into cytosol#GO:0097553;regulation of ion transport#GO:0043269;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;transport#GO:0006810;cytosolic calcium ion transport#GO:0060401;regulation of system process#GO:0044057;cation transport#GO:0006812;cellular homeostasis#GO:0019725;sequestering of calcium ion#GO:0051208;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;negative regulation of sequestering of calcium ion#GO:0051283;muscle system process#GO:0003012;muscle contraction#GO:0006936 membrane-enclosed lumen#GO:0031974;sarcoplasmic reticulum#GO:0016529;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 calcium-binding protein#PC00060 HUMAN|HGNC=37271|UniProtKB=A6NMK8 A6NMK8 INSYN2B PTHR28682:SF2 INHIBITORY SYNAPTIC FACTOR 2A-RELATED PROTEIN INSYN2B cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;chemical synaptic transmission, postsynaptic#GO:0099565;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;asymmetric synapse#GO:0032279 HUMAN|HGNC=3218|UniProtKB=Q12805 Q12805 EFEMP1 PTHR24039:SF33 FIBRILLIN-RELATED EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 1 extracellular matrix structural protein#PC00103 HUMAN|HGNC=14831|UniProtKB=Q8NGG5 Q8NGG5 OR8K1 PTHR48018:SF81 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=368|UniProtKB=O43572 O43572 AKAP10 PTHR13155:SF1 A-KINASE ANCHOR PROTEINS A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL scaffold/adaptor protein#PC00226 HUMAN|HGNC=25105|UniProtKB=Q9H930 Q9H930 SP140L PTHR46386:SF6 NUCLEAR BODY PROTEIN SP140 NUCLEAR BODY PROTEIN SP140-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=3700|UniProtKB=P07954 P07954 FH PTHR11444:SF1 ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE FUMARATE HYDRATASE, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 TCA cycle#P00051>Fumarase#P01271 HUMAN|HGNC=17820|UniProtKB=Q9H0P0 Q9H0P0 NT5C3A PTHR13045:SF12 5'-NUCLEOTIDASE CYTOSOLIC 5'-NUCLEOTIDASE 3A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 esterase#PC00097 HUMAN|HGNC=25492|UniProtKB=Q5PRF9 Q5PRF9 SAMD4B PTHR12515:SF9 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED PROTEIN SMAUG HOMOLOG 2 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;nuclear-transcribed mRNA catabolic process#GO:0000956;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cellular protein metabolic process#GO:0032269;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=17712|UniProtKB=O15304 O15304 SIVA1 PTHR14365:SF1 APOPTOSIS REGULATORY PROTEIN SIVA APOPTOSIS REGULATORY PROTEIN SIVA protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 HUMAN|HGNC=9843|UniProtKB=O60894 O60894 RAMP1 PTHR14076:SF3 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular localization#GO:0051641;membrane organization#GO:0061024;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;anatomical structure morphogenesis#GO:0009653;membrane invagination#GO:0010324;establishment of localization#GO:0051234;tube morphogenesis#GO:0035239;divalent inorganic cation transport#GO:0072511;vasculature development#GO:0001944;organic substance metabolic process#GO:0071704;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;blood vessel morphogenesis#GO:0048514;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;tube development#GO:0035295;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;protein transport#GO:0015031;blood vessel development#GO:0001568;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;receptor internalization#GO:0031623;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;transport#GO:0006810;cation transport#GO:0006812;calcium ion transport#GO:0006816;amide transport#GO:0042886;system development#GO:0048731;organic substance transport#GO:0071702;divalent metal ion transport#GO:0070838;response to endogenous stimulus#GO:0009719;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;cellular response to chemical stimulus#GO:0070887;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;ion transport#GO:0006811;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;localization#GO:0051179;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;biological regulation#GO:0065007 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 HUMAN|HGNC=20275|UniProtKB=Q9NRG7 Q9NRG7 SDR39U1 PTHR11092:SF0 SUGAR NUCLEOTIDE EPIMERASE RELATED EPIMERASE FAMILY PROTEIN SDR39U1 epimerase/racemase#PC00096 HUMAN|HGNC=11269|UniProtKB=O43609 O43609 SPRY1 PTHR12365:SF10 SPROUTY PROTEIN SPROUTY HOMOLOG 1 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;regulation of Ras protein signal transduction#GO:0046578;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;MAPK cascade#GO:0000165;protein modification process#GO:0036211;negative regulation of Ras protein signal transduction#GO:0046580;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;response to endogenous stimulus#GO:0009719;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of small GTPase mediated signal transduction#GO:0051058;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;negative regulation of MAP kinase activity#GO:0043407;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Spry#P00541;EGF receptor signaling pathway#P00018>SPRY#G01511;FGF signaling pathway#P00021>Spry#P00626 HUMAN|HGNC=30522|UniProtKB=Q8N4P3 Q8N4P3 HDDC3 PTHR46246:SF1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 hydrolase#PC00121 HUMAN|HGNC=24499|UniProtKB=Q8NE09 Q8NE09 RGS22 PTHR46583:SF1 REGULATOR OF G-PROTEIN SIGNALING 22 REGULATOR OF G-PROTEIN SIGNALING 22 HUMAN|HGNC=5650|UniProtKB=P06331 P06331 IGHV4-34 PTHR23266:SF238 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 4-34 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=17360|UniProtKB=Q96JA1 Q96JA1 LRIG1 PTHR24373:SF273 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS PROTEIN 1 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=5198|UniProtKB=Q9Y662 Q9Y662 HS3ST3B1 PTHR10605:SF7 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 3B1 transferase#PC00220 HUMAN|HGNC=12149|UniProtKB=P01737 P01737 TRAV8-4 PTHR19367:SF24 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-4 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=198|UniProtKB=Q99965 Q99965 ADAM2 PTHR11905:SF108 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 2 cell recognition#GO:0008037;fertilization#GO:0009566;reproduction#GO:0000003;single fertilization#GO:0007338;biological adhesion#GO:0022610;sexual reproduction#GO:0019953;reproductive process#GO:0022414;cell adhesion#GO:0007155;sperm-egg recognition#GO:0035036;cellular process#GO:0009987;multi-organism reproductive process#GO:0044703;multi-organism process#GO:0051704;binding of sperm to zona pellucida#GO:0007339;cell-cell recognition#GO:0009988 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=24352|UniProtKB=Q8IZW8 Q8IZW8 TNS4 PTHR45734:SF6 TENSIN TENSIN-4 non-motor actin binding protein#PC00165 HUMAN|HGNC=5283|UniProtKB=P15515 P15515 HTN1 PTHR15057:SF2 STATHERIN HISTATIN-1 HUMAN|HGNC=17302|UniProtKB=Q7Z3B1 Q7Z3B1 NEGR1 PTHR42757:SF6 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED NEURONAL GROWTH REGULATOR 1 immunoglobulin#PC00123 HUMAN|HGNC=24483|UniProtKB=Q9Y4R7 Q9Y4R7 TTLL3 PTHR45870:SF1 TUBULIN MONOGLYCYLASE TTLL3 TUBULIN MONOGLYCYLASE TTLL3 HUMAN|HGNC=6768|UniProtKB=Q15796 Q15796 SMAD2 PTHR13703:SF42 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;ubiquitin protein ligase binding#GO:0031625;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;nucleobase-containing compound metabolic process#GO:0006139;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;response to BMP#GO:0071772;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;BMP signaling pathway#GO:0030509;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;response to growth factor#GO:0070848;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to growth factor stimulus#GO:0071363;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 HUMAN|HGNC=24046|UniProtKB=Q969Q4 Q969Q4 ARL11 PTHR11711:SF172 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 11 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein#PC00020 HUMAN|HGNC=22979|UniProtKB=P09131 P09131 SLC10A3 PTHR10361:SF3 SODIUM-BILE ACID COTRANSPORTER P3 PROTEIN inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monocarboxylic acid transmembrane transporter activity#GO:0008028;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 primary active transporter#PC00068 HUMAN|HGNC=2940|UniProtKB=Q9P2D7 Q9P2D7 DNAH1 PTHR10676:SF358 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN 1, AXONEMAL pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement#GO:0003341 supramolecular complex#GO:0099080;axoneme#GO:0005930;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=30685|UniProtKB=P40222 P40222 TXLNA PTHR16127:SF12 TAXILIN ALPHA-TAXILIN membrane traffic protein#PC00150 HUMAN|HGNC=11446|UniProtKB=O00186 O00186 STXBP3 PTHR11679:SF33 VESICLE PROTEIN SORTING-ASSOCIATED SYNTAXIN-BINDING PROTEIN 3 syntaxin binding#GO:0019905;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488;syntaxin-1 binding#GO:0017075 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of neurotransmitter levels#GO:0001505;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;export from cell#GO:0140352 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=13536|UniProtKB=Q8TF62 Q8TF62 ATP8B4 PTHR24092:SF80 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IM-RELATED pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=12780|UniProtKB=P09544 P09544 WNT2 PTHR12027:SF86 WNT RELATED PROTEIN WNT-2 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=3312|UniProtKB=Q15717 Q15717 ELAVL1 PTHR10352:SF13 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 1 translation initiation factor#PC00224 CCKR signaling map#P06959>HuR#G07273;CCKR signaling map#P06959>HuR#P07211;CCKR signaling map#P06959>HuR#G06980 HUMAN|HGNC=16193|UniProtKB=Q96MM6 Q96MM6 HSPA12B PTHR14187:SF39 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12B HUMAN|HGNC=17206|UniProtKB=Q9NWH2 Q9NWH2 TMEM242 PTHR13141:SF4 TRANSMEMBRANE PROTEIN 242 TRANSMEMBRANE PROTEIN 242 HUMAN|HGNC=7461|UniProtKB=P03915 P03915 MT-ND5 PTHR42829:SF2 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655 oxidoreductase#PC00176 HUMAN|HGNC=19138|UniProtKB=Q53EV4 Q53EV4 LRRC23 PTHR15454:SF47 NISCHARIN RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 23 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20151|UniProtKB=Q8NDX2 Q8NDX2 SLC17A8 PTHR11662:SF207 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;L-glutamate transmembrane transporter activity#GO:0005313;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;ion transport#GO:0006811;transport#GO:0006810;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;regulation of synapse structure or activity#GO:0050803;synaptic transmission, glutamatergic#GO:0035249;signaling#GO:0023052;cell-cell signaling#GO:0007267;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;transport vesicle membrane#GO:0030658;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 Ionotropic glutamate receptor pathway#P00037>Vglut#P01021 HUMAN|HGNC=30527|UniProtKB=Q8IXP5 Q8IXP5 C11orf53 PTHR28376:SF1 RGD1562914 RGD1562914 HUMAN|HGNC=29832|UniProtKB=Q6IA69 Q6IA69 NADSYN1 PTHR23090:SF9 NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 HUMAN|HGNC=28229|UniProtKB=Q9BRT6 Q9BRT6 LLPH PTHR34253:SF3 PROTEIN LLP HOMOLOG PROTEIN LLP HOMOLOG nucleic acid binding#GO:0003676;basal RNA polymerase II transcription machinery binding#GO:0001099;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;basal transcription machinery binding#GO:0001098 neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;developmental cell growth#GO:0048588;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;neuron projection development#GO:0031175;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=30930|UniProtKB=Q8WWM1 Q8WWM1 XAGE5 PTHR14047:SF33 P ANTIGEN FAMILY MEMBER 5-RELATED X ANTIGEN FAMILY MEMBER 5 HUMAN|HGNC=24987|UniProtKB=Q9HBL8 Q9HBL8 NMRAL1 PTHR42748:SF16 NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER NMRA-LIKE FAMILY DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=6204|UniProtKB=P05412 P05412 JUN PTHR11462:SF8 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR AP-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>JUN#P06757;Gonadotropin-releasing hormone receptor pathway#P06664>Junc#G06891;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;PDGF signaling pathway#P00047>c-Jun#P01163;B cell activation#P00010>jun#P00401;FAS signaling pathway#P00020>c-Jun#P00601;CCKR signaling map#P06959>JUN#G06983;Gonadotropin-releasing hormone receptor pathway#P06664>Junc#G06677;Toll receptor signaling pathway#P00054>AP1#P01355;Gonadotropin-releasing hormone receptor pathway#P06664>Junc#P06710;Angiogenesis#P00005>c-Jun#P00220;Oxidative stress response#P00046>c-jun#P01132;CCKR signaling map#P06959>JUN#P07114;Ras Pathway#P04393>AP1#P04560;Apoptosis signaling pathway#P00006>c-Jun#P00303;Huntington disease#P00029>c-Jun#P00776;T cell activation#P00053>jun#P01335;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838;CCKR signaling map#P06959>JUN#G07276 HUMAN|HGNC=9362|UniProtKB=P13727 P13727 PRG2 PTHR10068:SF16 BONE MARROW PROTEOGLYCAN BONE MARROW PROTEOGLYCAN extracellular matrix structural protein#PC00103 HUMAN|Ensembl=ENSG00000282150|UniProtKB=A0A0J9YY99 A0A0J9YY99 ENSG00000282150 PTHR23266:SF241 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=25225|UniProtKB=Q8TBH0 Q8TBH0 ARRDC2 PTHR11188:SF48 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 2 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 HUMAN|HGNC=26617|UniProtKB=Q8NB16 Q8NB16 MLKL PTHR44329:SF15 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cell periphery#GO:0071944;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=17183|UniProtKB=Q9H765 Q9H765 ASB8 PTHR24134:SF9 ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043 ANKYRIN REPEAT AND SOCS BOX PROTEIN 8 HUMAN|HGNC=9688|UniProtKB=Q6NZI2 Q6NZI2 CAVIN1 PTHR15240:SF3 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;plasma membrane raft#GO:0044853;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane region#GO:0098589;membrane microdomain#GO:0098857;plasma membrane#GO:0005886;whole membrane#GO:0098805 membrane traffic protein#PC00150 General transcription by RNA polymerase I#P00022>PTRF#P00656 HUMAN|HGNC=6218|UniProtKB=Q09470 Q09470 KCNA1 PTHR11537:SF24 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;cell junction#GO:0030054;dendrite#GO:0030425;cellular anatomical entity#GO:0110165;dendritic tree#GO:0097447;cell periphery#GO:0071944;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;axon#GO:0030424;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;cell body#GO:0044297;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=25641|UniProtKB=Q5VYX0 Q5VYX0 RNLS PTHR23357:SF1 UNCHARACTERIZED RENALASE HUMAN|HGNC=30003|UniProtKB=Q5VUE5 Q5VUE5 C1orf53 PTHR21037:SF2 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL SIMILAR TO NOVEL PROTEIN ribosomal protein#PC00202 HUMAN|HGNC=9788|UniProtKB=P51149 P51149 RAB7A PTHR47981:SF13 RAB FAMILY RAS-RELATED PROTEIN RAB-7A lysosome organization#GO:0007040;vesicle fusion#GO:0006906;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;phagocytosis#GO:0006909;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;endosome to lysosome transport#GO:0008333;cellular process#GO:0009987;lysosomal transport#GO:0007041;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=378|UniProtKB=O43823 O43823 AKAP8 PTHR12190:SF6 A-KINASE ANCHOR PROTEIN AKAP 8 A-KINASE ANCHOR PROTEIN 8 protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;binding#GO:0005488 membrane-enclosed lumen#GO:0031974;nuclear periphery#GO:0034399;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25675|UniProtKB=Q96FZ7 Q96FZ7 CHMP6 PTHR22761:SF5 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 6 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=11950|UniProtKB=P45378 P45378 TNNT3 PTHR11521:SF4 TROPONIN T TROPONIN T, FAST SKELETAL MUSCLE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 actin binding motor protein#PC00040 HUMAN|HGNC=30888|UniProtKB=Q96DN5 Q96DN5 TBC1D31 PTHR19853:SF1 WD REPEAT CONTAINING PROTEIN 3 WDR3 TBC1 DOMAIN FAMILY MEMBER 31 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=25939|UniProtKB=Q96GS4 Q96GS4 BORCS6 PTHR13440:SF7 UNCHARACTERIZED BLOC-1-RELATED COMPLEX SUBUNIT 6 lysosome localization#GO:0032418;localization#GO:0051179;cellular localization#GO:0051641;organelle localization#GO:0051640;cellular process#GO:0009987 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=10885|UniProtKB=Q96FS4 Q96FS4 SIPA1 PTHR15711:SF14 RAP GTPASE-ACTIVATING PROTEIN SIGNAL-INDUCED PROLIFERATION-ASSOCIATED PROTEIN 1 GTPase-activating protein#PC00257 HUMAN|HGNC=29661|UniProtKB=Q96E52 Q96E52 OMA1 PTHR22726:SF1 METALLOENDOPEPTIDASE OMA1 METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL metalloprotease#PC00153 HUMAN|HGNC=197|UniProtKB=Q9H013 Q9H013 ADAM19 PTHR11905:SF19 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 19 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;membrane protein ectodomain proteolysis#GO:0006509;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=26507|UniProtKB=Q1HG43 Q1HG43 DUOXA1 PTHR31158:SF3 DUAL OXIDASE 2 DUAL OXIDASE MATURATION FACTOR 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 oxidase#PC00175 HUMAN|HGNC=7390|UniProtKB=Q2TV78 Q2TV78 MST1L PTHR24261:SF12 PLASMINOGEN-RELATED HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 HUMAN|HGNC=17884|UniProtKB=Q8NHX4 Q8NHX4 SPATA3 PTHR22234:SF0 TESTIS SPERMATOCYTE APOPTOSIS-RELATED GENE 1 PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 3 HUMAN|HGNC=25922|UniProtKB=Q8N539 Q8N539 FIBCD1 PTHR19143:SF45 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C DOMAIN-CONTAINING PROTEIN 1 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=8138|UniProtKB=Q9UBC0 Q9UBC0 ONECUT1 PTHR14057:SF9 TRANSCRIPTION FACTOR ONECUT HEPATOCYTE NUCLEAR FACTOR 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=32261|UniProtKB=P0C7W8 P0C7W8 FAM90A13P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=30964|UniProtKB=Q5W041 Q5W041 ARMC3 PTHR46618:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 3 ARMADILLO REPEAT-CONTAINING PROTEIN 3 HUMAN|HGNC=29263|UniProtKB=Q96B67 Q96B67 ARRDC3 PTHR11188:SF49 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 3 amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;protein transport#GO:0015031;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=35463|UniProtKB=A6NLX3 A6NLX3 SPDYE4 PTHR31156:SF11 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E4 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=32253|UniProtKB=A8MXJ8 A8MXJ8 FAM90A5P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=24712|UniProtKB=Q5VWP2 Q5VWP2 TENT5C PTHR12974:SF34 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5C adenylyltransferase activity#GO:0070566;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;negative regulation of cellular catabolic process#GO:0031330;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265 HUMAN|HGNC=30654|UniProtKB=Q8IZH2 Q8IZH2 XRN1 PTHR12341:SF7 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;heterocyclic compound binding#GO:1901363;exonuclease activity#GO:0004527 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 exoribonuclease#PC00099 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 HUMAN|HGNC=16196|UniProtKB=Q96PH6 Q96PH6 DEFB118 PTHR15001:SF7 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 118 antimicrobial response protein#PC00051 HUMAN|HGNC=7691|UniProtKB=O95182 O95182 NDUFA7 PTHR12485:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 7 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=14148|UniProtKB=Q96S16 Q96S16 JMJD8 PTHR12480:SF35 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD JMJC DOMAIN-CONTAINING PROTEIN 8 protein modifying enzyme#PC00260 HUMAN|HGNC=15510|UniProtKB=P47883 P47883 OR3A4P PTHR48001:SF100 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 3A4-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=16067|UniProtKB=Q8IZQ8 Q8IZQ8 MYOCD PTHR22793:SF11 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN cellular developmental process#GO:0048869;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;circulatory system development#GO:0072359;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;developmental process#GO:0032502;cellular process#GO:0009987;tissue development#GO:0009888;muscle tissue development#GO:0060537;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;system development#GO:0048731;cell differentiation#GO:0030154;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;cardiocyte differentiation#GO:0035051;multicellular organismal process#GO:0032501 DNA-binding transcription factor#PC00218 HUMAN|HGNC=23571|UniProtKB=Q53SF7 Q53SF7 COBLL1 PTHR21557:SF2 CORDON-BLEU CORDON-BLEU PROTEIN-LIKE 1 HUMAN|HGNC=34548|UniProtKB=A6NDP7 A6NDP7 MYADML2 PTHR17068:SF5 MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER MYELOID-ASSOCIATED DIFFERENTIATION MARKER-LIKE PROTEIN 2 HUMAN|HGNC=37200|UniProtKB=A6NM45 A6NM45 CLDN24 PTHR12002:SF84 CLAUDIN CLAUDIN-24-RELATED cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=4217|UniProtKB=Q9UK05 Q9UK05 GDF2 PTHR11848:SF157 TGF-BETA FAMILY GROWTH/DIFFERENTIATION FACTOR 2 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=10592|UniProtKB=Q8IWT1 Q8IWT1 SCN4B PTHR13869:SF14 MYELIN P0 RELATED SODIUM CHANNEL SUBUNIT BETA-4 myelin protein#PC00161 HUMAN|HGNC=18646|UniProtKB=Q53GQ0 Q53GQ0 HSD17B12 PTHR43899:SF14 RH59310P VERY-LONG-CHAIN 3-OXOACYL-COA REDUCTASE HUMAN|HGNC=13740|UniProtKB=Q9NSN8 Q9NSN8 SNTG1 PTHR10554:SF2 SYNTROPHIN GAMMA-1-SYNTROPHIN membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 HUMAN|HGNC=14899|UniProtKB=Q8WXS8 Q8WXS8 ADAMTS14 PTHR13723:SF24 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 14 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=10256|UniProtKB=Q01973 Q01973 ROR1 PTHR24416:SF134 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of transferase activity#GO:0051347;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of transferase activity#GO:0051338;regulation of cellular macromolecule biosynthetic process#GO:2000112 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=3443|UniProtKB=O14944 O14944 EREG PTHR10740:SF11 TRANSFORMING GROWTH FACTOR ALPHA PROEPIREGULIN regulation of protein metabolic process#GO:0051246;positive regulation of signal transduction#GO:0009967;nuclear division#GO:0000280;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;positive regulation of protein modification process#GO:0031401;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;peptidyl-tyrosine phosphorylation#GO:0018108;positive regulation of mitotic cell cycle#GO:0045931;cellular protein metabolic process#GO:0044267;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;positive regulation of transferase activity#GO:0051347;organic cyclic compound metabolic process#GO:1901360;positive regulation of cell cycle process#GO:0090068;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;positive regulation of macromolecule biosynthetic process#GO:0010557;mitotic nuclear division#GO:0140014;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;signaling#GO:0023052;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of signaling receptor activity#GO:0010469;positive regulation of protein metabolic process#GO:0051247;cell surface receptor signaling pathway#GO:0007166;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;regulation of mitotic cell cycle#GO:0007346;regulation of DNA replication#GO:0006275;regulation of mitotic nuclear division#GO:0007088;regulation of protein modification process#GO:0031399;positive regulation of DNA replication#GO:0045740;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;epidermal growth factor receptor signaling pathway#GO:0007173;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of organelle organization#GO:0033043;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;peptidyl-amino acid modification#GO:0018193;mitotic cell cycle process#GO:1903047;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of mitotic nuclear division#GO:0045840;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;peptidyl-tyrosine modification#GO:0018212;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;organelle organization#GO:0006996;biological regulation#GO:0065007;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;DNA replication#GO:0006260;regulation of transferase activity#GO:0051338;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 HUMAN|HGNC=17109|UniProtKB=Q8TE56 Q8TE56 ADAMTS17 PTHR13723:SF151 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 17 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=74|UniProtKB=Q9UNQ0 Q9UNQ0 ABCG2 PTHR48041:SF92 ABC TRANSPORTER G FAMILY MEMBER 28 BROAD SUBSTRATE SPECIFICITY ATP-BINDING CASSETTE TRANSPORTER ABCG2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=37269|UniProtKB=A1L167 A1L167 UBE2QL1 PTHR24068:SF72 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2Q-LIKE PROTEIN 1 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=15984|UniProtKB=Q7Z2E3 Q7Z2E3 APTX PTHR12486:SF4 APRATAXIN-RELATED APRATAXIN hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;double-stranded DNA binding#GO:0003690;exonuclease activity#GO:0004527;deoxyribonuclease activity#GO:0004536;mismatched DNA binding#GO:0030983;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;exodeoxyribonuclease activity#GO:0004529;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;double-stranded RNA binding#GO:0003725;exodeoxyribonuclease activity, producing 5'-phosphomonoesters#GO:0016895 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 damaged DNA-binding protein#PC00086 HUMAN|HGNC=28730|UniProtKB=Q86XU0 Q86XU0 ZNF677 PTHR24377:SF698 IP01015P-RELATED ZINC FINGER PROTEIN 677 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25917|UniProtKB=Q96SL8 Q96SL8 FIZ1 PTHR24383:SF13 ZINC FINGER PROTEIN FLT3-INTERACTING ZINC FINGER PROTEIN 1 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6040|UniProtKB=Q13418 Q13418 ILK PTHR44329:SF57 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED INTEGRIN-LINKED PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell morphogenesis involved in differentiation#GO:0000904;developmental process#GO:0032502;biological adhesion#GO:0022610;substrate adhesion-dependent cell spreading#GO:0034446;cell morphogenesis#GO:0000902;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell development#GO:0048468;response to stimulus#GO:0050896;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;anchoring junction#GO:0070161;cell junction#GO:0030054;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856 non-receptor serine/threonine protein kinase#PC00167 Integrin signalling pathway#P00034>ILK#P00935 HUMAN|HGNC=9210|UniProtKB=P28069 P28069 POU1F1 PTHR11636:SF84 POU DOMAIN PITUITARY-SPECIFIC POSITIVE TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=7096|UniProtKB=Q9UJV3 Q9UJV3 MID2 PTHR24099:SF12 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE MID2-RELATED ubiquitin-protein ligase#PC00234 HUMAN|HGNC=6934|UniProtKB=P43121 P43121 MCAM PTHR11973:SF18 CELL SURFACE GLYCOPROTEIN MUC18-RELATED CELL SURFACE GLYCOPROTEIN MUC18 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=23619|UniProtKB=Q9UFN0 Q9UFN0 NIPSNAP3A PTHR21017:SF23 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 3A cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7596|UniProtKB=O43795 O43795 MYO1B PTHR13140:SF277 MYOSIN UNCONVENTIONAL MYOSIN-IB pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 microvillus#GO:0005902;supramolecular complex#GO:0099080;brush border#GO:0005903;actin filament bundle#GO:0032432;cluster of actin-based cell projections#GO:0098862;actin-based cell projection#GO:0098858;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;actin filament#GO:0005884;membrane#GO:0016020;vesicle#GO:0031982;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=13328|UniProtKB=Q13325 Q13325 IFIT5 PTHR10271:SF28 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=37219|UniProtKB=B4DJY2 B4DJY2 TMEM233 PTHR14948:SF19 NG5 TRANSMEMBRANE PROTEIN 233 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=687|UniProtKB=O95661 O95661 DIRAS3 PTHR24070:SF269 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN DI-RAS3 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=6210|UniProtKB=P27701 P27701 CD82 PTHR19282:SF44 TETRASPANIN CD82 ANTIGEN intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 p53 pathway#P00059>KAI#G04704 HUMAN|HGNC=30368|UniProtKB=O95886 O95886 DLGAP3 PTHR12353:SF4 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 3 molecular adaptor activity#GO:0060090;binding#GO:0005488 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;regulation of neurotransmitter receptor activity#GO:0099601;chemical synaptic transmission, postsynaptic#GO:0099565;system process#GO:0003008;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;regulation of system process#GO:0044057;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;signaling#GO:0023052 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;postsynapse#GO:0098794;synapse#GO:0045202;postsynaptic specialization#GO:0099572;cellular anatomical entity#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11190|UniProtKB=P56693 P56693 SOX10 PTHR45803:SF6 SOX100B TRANSCRIPTION FACTOR SOX-10 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;mesenchymal cell differentiation#GO:0048762;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;mesenchyme development#GO:0060485;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;neural crest cell development#GO:0014032;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;cell motility#GO:0048870;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;stem cell differentiation#GO:0048863;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;cell migration#GO:0016477;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12562|UniProtKB=Q9BZX2 Q9BZX2 UCK2 PTHR10285:SF131 URIDINE KINASE URIDINE-CYTIDINE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 HUMAN|HGNC=15631|UniProtKB=Q9NYK1 Q9NYK1 TLR7 PTHR47410:SF2 TOLL-LIKE RECEPTOR 7-RELATED TOLL-LIKE RECEPTOR 7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;defense response to virus#GO:0051607;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;response to virus#GO:0009615;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;pattern recognition receptor signaling pathway#GO:0002221;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR2,4,7#P01351;Toll receptor signaling pathway#P00054>TLR#P01346 HUMAN|HGNC=5988|UniProtKB=Q13478 Q13478 IL18R1 PTHR11890:SF6 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-18 RECEPTOR 1 transmembrane signal receptor#PC00197 HUMAN|HGNC=7097|UniProtKB=P14174 P14174 MIF PTHR11954:SF6 D-DOPACHROME DECARBOXYLASE MACROPHAGE MIGRATION INHIBITORY FACTOR decarboxylase#PC00089 HUMAN|HGNC=37229|UniProtKB=A6NEM1 A6NEM1 GOLGA6L9 PTHR23143:SF19 TRICHOHYALIN-RELATED GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 10-RELATED actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=9462|UniProtKB=P60891 P60891 PRPS1 PTHR10210:SF60 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172 HUMAN|HGNC=12986|UniProtKB=O14628 O14628 ZNF195 PTHR24384:SF87 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 195 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=24847|UniProtKB=Q9H4M3 Q9H4M3 FBXO44 PTHR12125:SF13 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 44 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 HUMAN|HGNC=21000|UniProtKB=Q4VC12 Q4VC12 MSS51 PTHR46920:SF1 FAMILY NOT NAMED PROTEIN MSS51 HOMOLOG, MITOCHONDRIAL-RELATED HUMAN|HGNC=21643|UniProtKB=O95857 O95857 TSPAN13 PTHR19282:SF203 TETRASPANIN TETRASPANIN-13 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=27998|UniProtKB=Q6NXP2 Q6NXP2 FAM71F2 PTHR22574:SF10 UNCHARACTERIZED PROTEIN FAM71F2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=28777|UniProtKB=Q9H773 Q9H773 DCTPP1 PTHR46523:SF1 DCTP PYROPHOSPHATASE 1 DCTP PYROPHOSPHATASE 1 phosphatase#PC00181 HUMAN|HGNC=34243|UniProtKB=A8MYB1 A8MYB1 TMCO5B PTHR22422:SF1 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5B-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 5B HUMAN|HGNC=11209|UniProtKB=Q02446 Q02446 SP4 PTHR23235:SF17 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=8738|UniProtKB=Q15113 Q15113 PCOLCE PTHR24251:SF24 OVOCHYMASE-RELATED PROCOLLAGEN C-ENDOPEPTIDASE ENHANCER 1 serine protease#PC00203 HUMAN|HGNC=2761|UniProtKB=P59665 P59665 DEFA1 PTHR11876:SF19 ALPHA-DEFENSIN 1 NEUTROPHIL DEFENSIN 1-RELATED response to external biotic stimulus#GO:0043207;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;antibacterial humoral response#GO:0019731;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;innate immune response#GO:0045087;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cellular response to biotic stimulus#GO:0071216;cellular process#GO:0009987;defense response to Gram-positive bacterium#GO:0050830;response to lipopolysaccharide#GO:0032496;defense response to Gram-negative bacterium#GO:0050829;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=33758|UniProtKB=A6NE02 A6NE02 BTBD17 PTHR24410:SF12 HL07962P-RELATED BTB/POZ DOMAIN-CONTAINING PROTEIN 17 HUMAN|HGNC=11830|UniProtKB=P04183 P04183 TK1 PTHR11441:SF0 THYMIDINE KINASE THYMIDINE KINASE, CYTOSOLIC transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086 nucleotide kinase#PC00172 Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine kinase#P03147;Salvage pyrimidine deoxyribonucleotides#P02774>Deoxyuridine kinase#P03146 HUMAN|HGNC=18303|UniProtKB=Q9UI12 Q9UI12 ATP6V1H PTHR10698:SF0 V-TYPE PROTON ATPASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT H ATP synthase#PC00002 HUMAN|HGNC=4179|UniProtKB=O75323 O75323 NIPSNAP2 PTHR21017:SF14 NIPSNAP-RELATED PROTEIN NIPSNAP HOMOLOG 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4235|UniProtKB=P14136 P14136 GFAP PTHR45652:SF9 GLIAL FIBRILLARY ACIDIC PROTEIN GLIAL FIBRILLARY ACIDIC PROTEIN HUMAN|HGNC=9833|UniProtKB=Q9UQ07 Q9UQ07 MOK PTHR24055:SF533 MITOGEN-ACTIVATED PROTEIN KINASE MAPK/MAK/MRK OVERLAPPING KINASE MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=18824|UniProtKB=Q96N95 Q96N95 ZNF396 PTHR23226:SF78 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 396 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20062|UniProtKB=Q9P275 Q9P275 USP36 PTHR24006:SF653 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=11387|UniProtKB=P31948 P31948 STIP1 PTHR22904:SF517 TPR REPEAT CONTAINING PROTEIN STRESS-INDUCED-PHOSPHOPROTEIN 1 heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488;Hsp90 protein binding#GO:0051879 HUMAN|HGNC=29619|UniProtKB=Q2M385 Q2M385 MPEG1 PTHR31463:SF4 MACROPHAGE-EXPRESSED GENE 1 PROTEIN MACROPHAGE-EXPRESSED GENE 1 PROTEIN response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response#GO:0006952 HUMAN|HGNC=7989|UniProtKB=P01111 P01111 NRAS PTHR24070:SF189 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE NRAS GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;FGF signaling pathway#P00021>Ras#P00633;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552;Angiogenesis#P00005>Ras#P00238;T cell activation#P00053>Ras#P01306;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Ras#P00869;B cell activation#P00010>Ras#P00376;Interleukin signaling pathway#P00036>Ras#P00977;Ras Pathway#P04393>Ras#P04547;PI3 kinase pathway#P00048>Ras#P01182;p53 pathway feedback loops 2#P04398>Ras#P04651;VEGF signaling pathway#P00056>Ras#P01411;Integrin signalling pathway#P00034>Ras#P00916 HUMAN|HGNC=29227|UniProtKB=Q9ULI3 Q9ULI3 HEG1 PTHR24037:SF3 HEART DEVELOPMENT PROTEIN WITH EGF-LIKE DOMAINS 1 PROTEIN HEG HOMOLOG 1 HUMAN|HGNC=25141|UniProtKB=Q96GE4 Q96GE4 CEP95 PTHR22545:SF0 UNCHARACTERIZED CENTROSOMAL PROTEIN OF 95 KDA HUMAN|HGNC=10801|UniProtKB=P07988 P07988 SFTPB PTHR11480:SF33 SAPOSIN-RELATED PULMONARY SURFACTANT-ASSOCIATED PROTEIN B extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29103|UniProtKB=O75185 O75185 ATP2C2 PTHR42861:SF23 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 2 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=27119|UniProtKB=Q17RN3 Q17RN3 FAM98C PTHR31353:SF10 FAM98 PROTEIN FAM98C protein-containing complex#GO:0032991;intracellular#GO:0005622 RNA splicing factor#PC00148 HUMAN|HGNC=8710|UniProtKB=Q9Y5G1 Q9Y5G1 PCDHGB3 PTHR24028:SF259 CADHERIN-87A PROTOCADHERIN GAMMA-B3-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=23605|UniProtKB=Q6L8G5 Q6L8G5 KRTAP5-10 PTHR23262:SF25 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-10-RELATED HUMAN|HGNC=11319|UniProtKB=P28290 P28290 ITPRID2 PTHR17469:SF11 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN ITPRID2 HUMAN|Ensembl=ENSG00000284484|UniProtKB=A0A1W2PPK0 A0A1W2PPK0 ENSG00000284484 PTHR24341:SF8 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX DOMAIN-CONTAINING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=11142|UniProtKB=P57059 P57059 SIK1 PTHR24343:SF204 SERINE/THREONINE KINASE SERINE/THREONINE-PROTEIN KINASE SIK1-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=30856|UniProtKB=Q96G21 Q96G21 IMP4 PTHR22734:SF2 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 RNA splicing factor#PC00148 HUMAN|HGNC=42973|UniProtKB=P0DKX4 P0DKX4 SMIM18 PTHR36982:SF1 FAMILY NOT NAMED SMALL INTEGRAL MEMBRANE PROTEIN 18 HUMAN|HGNC=11778|UniProtKB=P21980 P21980 TGM2 PTHR11590:SF6 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 2 transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular protein modification process#GO:0006464 transferase#PC00220 HUMAN|HGNC=30059|UniProtKB=Q643R3 Q643R3 LPCAT4 PTHR23063:SF7 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHOLIPID ACYLTRANSFERASE LPCAT4 acyltransferase#PC00042 HUMAN|HGNC=18224|UniProtKB=Q9UGI0 Q9UGI0 ZRANB1 PTHR13367:SF28 UBIQUITIN THIOESTERASE UBIQUITIN THIOESTERASE ZRANB1 thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;omega peptidase activity#GO:0008242;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 positive regulation of signal transduction#GO:0009967;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;cytoskeleton organization#GO:0007010;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;cellular component organization#GO:0016043;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;protein modification by small protein removal#GO:0070646;movement of cell or subcellular component#GO:0006928;protein deubiquitination#GO:0016579;locomotion#GO:0040011;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;signaling#GO:0023052;cell-cell signaling#GO:0007267;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;cellular protein catabolic process#GO:0044257;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;cell migration#GO:0016477;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=496|UniProtKB=P57078 P57078 RIPK4 PTHR24198:SF65 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 4 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=14522|UniProtKB=Q9UGB7 Q9UGB7 MIOX PTHR12588:SF0 MYOINOSITOL OXYGENASE INOSITOL OXYGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organic hydroxy compound metabolic process#GO:1901615;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 oxygenase#PC00177 HUMAN|HGNC=14881|UniProtKB=O60315 O60315 ZEB2 PTHR24391:SF11 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER E-BOX-BINDING HOMEOBOX 2 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20842|UniProtKB=Q8IVH2 Q8IVH2 FOXP4 PTHR45796:SF7 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX PROTEIN P4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28465|UniProtKB=Q8WV48 Q8WV48 CCDC107 PTHR37345:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 107 COILED-COIL DOMAIN-CONTAINING PROTEIN 107 HUMAN|HGNC=17230|UniProtKB=Q9BYQ9 Q9BYQ9 KRTAP4-8 PTHR23262:SF67 KERATIN ASSOCIATED PROTEIN HCG2042992-RELATED HUMAN|HGNC=11243|UniProtKB=Q9Y657 Q9Y657 SPIN1 PTHR10405:SF15 SPINDLIN SPINDLIN-1 HUMAN|HGNC=27954|UniProtKB=Q6ZMR5 Q6ZMR5 TMPRSS11A PTHR24253:SF41 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 11A serine protease#PC00203 HUMAN|HGNC=8859|UniProtKB=Q13608 Q13608 PEX6 PTHR23077:SF9 AAA-FAMILY ATPASE PEROXISOME ASSEMBLY FACTOR 2 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein targeting to peroxisome#GO:0006625;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein localization to peroxisome#GO:0072662;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;microbody membrane#GO:0031903;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777 HUMAN|HGNC=1464|UniProtKB=Q16566 Q16566 CAMK4 PTHR24349:SF338 SERINE/THREONINE-PROTEIN KINASE CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;protein autophosphorylation#GO:0046777;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>CaMKIV#P07198 HUMAN|HGNC=1337|UniProtKB=Q7LBC6 Q7LBC6 KDM3B PTHR12549:SF8 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE 3B nucleic acid binding#GO:0003676;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;catalytic activity, acting on a protein#GO:0140096 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;demethylation#GO:0070988;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;protein demethylation#GO:0006482;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=8670|UniProtKB=Q9UN74 Q9UN74 PCDHA4 PTHR24028:SF82 CADHERIN-87A PROTOCADHERIN ALPHA-4 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=23346|UniProtKB=Q0VAA2 Q0VAA2 LRRC74A PTHR24114:SF40 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74A HUMAN|HGNC=4458|UniProtKB=P06744 P06744 GPI PTHR11469:SF1 GLUCOSE-6-PHOSPHATE ISOMERASE GLUCOSE-6-PHOSPHATE ISOMERASE carbohydrate binding#GO:0030246;isomerase activity#GO:0016853;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;monosaccharide metabolic process#GO:0005996;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;oxoacid metabolic process#GO:0043436;carbohydrate biosynthetic process#GO:0016051;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glucose metabolic process#GO:0006006;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 isomerase#PC00135 Pentose phosphate pathway#P02762>Glucose-P-Isomerase#P03080;Glycolysis#P00024>Phosphoglucose isomerase#P00674 HUMAN|HGNC=26022|UniProtKB=Q7L0Y3 Q7L0Y3 TRMT10C PTHR13563:SF5 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG C tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;ribonuclease P complex#GO:0030677;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA methyltransferase#PC00033 HUMAN|HGNC=16280|UniProtKB=Q9NQ86 Q9NQ86 TRIM36 PTHR24099:SF18 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM36 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=19180|UniProtKB=Q7L0R7 Q7L0R7 RNF44 PTHR46171:SF2 GH10160P RING FINGER PROTEIN 44 HUMAN|HGNC=6946|UniProtKB=O60318 O60318 MCM3AP PTHR12436:SF36 80 KDA MCM3-ASSOCIATED PROTEIN GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=7001|UniProtKB=O14770 O14770 MEIS2 PTHR11850:SF47 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS2 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;visual system development#GO:0150063;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=30487|UniProtKB=Q6PK81 Q6PK81 ZNF773 PTHR24377:SF691 IP01015P-RELATED ZINC FINGER PROTEIN 773 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18576|UniProtKB=P22674 P22674 CCNO PTHR10177:SF401 CYCLINS CYCLIN-O cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 HUMAN|HGNC=7532|UniProtKB=P20591 P20591 MX1 PTHR11566:SF217 DYNAMIN INTERFERON-INDUCED GTP-BINDING PROTEIN MX1 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;membrane organization#GO:0061024;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;membrane fission#GO:0090148;vesicle localization#GO:0051648;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;protein transport#GO:0015031;biological regulation#GO:0065007;protein polymerization#GO:0051258;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;regulation of synapse structure or activity#GO:0050803;mitochondrial fission#GO:0000266;vesicle-mediated transport in synapse#GO:0099003;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;non-membrane-bounded organelle#GO:0043228;membrane coat#GO:0030117;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;mitochondrial envelope#GO:0005740;plasma membrane region#GO:0098590;postsynapse#GO:0098794;coated membrane#GO:0048475;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;envelope#GO:0031975;membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;intracellular vesicle#GO:0097708;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;mitochondrion#GO:0005739;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=20808|UniProtKB=Q9H8G1 Q9H8G1 ZNF430 PTHR24384:SF131 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 100-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=22125|UniProtKB=O95522 O95522 PRAMEF12 PTHR14224:SF103 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 12 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=25198|UniProtKB=Q96AG3 Q96AG3 SLC25A46 PTHR21252:SF2 TB1 PROTEIN-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 46 HUMAN|HGNC=115|UniProtKB=P53396 P53396 ACLY PTHR23118:SF0 ATP-CITRATE SYNTHASE ATP-CITRATE SYNTHASE transferase#PC00220 Pyruvate metabolism#P02772>Citrate Lyase#P03137 HUMAN|HGNC=15079|UniProtKB=Q6IEY1 Q6IEY1 OR4F29 PTHR48002:SF1 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4F21-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=18117|UniProtKB=O75525 O75525 KHDRBS3 PTHR11208:SF29 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA splicing factor#PC00148 HUMAN|HGNC=21360|UniProtKB=Q9HCI6 Q9HCI6 KIAA1586 PTHR46880:SF8 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN E3 SUMO-PROTEIN LIGASE KIAA1586 HUMAN|HGNC=7213|UniProtKB=O00566 O00566 MPHOSPH10 PTHR17039:SF0 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 HUMAN|HGNC=24035|UniProtKB=Q9UKG1 Q9UKG1 APPL1 PTHR46415:SF3 ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2 DCC-INTERACTING PROTEIN 13-ALPHA bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=13520|UniProtKB=Q14696 Q14696 MESD PTHR17600:SF2 MESODERM DEVELOPMENT CANDIDATE 2 LRP CHAPERONE MESD HUMAN|HGNC=17839|UniProtKB=Q8NHZ8 Q8NHZ8 CDC26 PTHR28579:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT CDC26 ANAPHASE-PROMOTING COMPLEX SUBUNIT CDC26 macromolecule modification#GO:0043412;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;mitotic nuclear division#GO:0140014;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein K11-linked ubiquitination#GO:0070979;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;cell cycle#GO:0007049;regulation of mitotic cell cycle#GO:0007346 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 HUMAN|HGNC=1834|UniProtKB=P17676 P17676 CEBPB PTHR23334:SF21 CCAAT/ENHANCER BINDING PROTEIN CCAAT/ENHANCER-BINDING PROTEIN BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=10327|UniProtKB=P61254 P61254 RPL26 PTHR11143:SF11 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER 60S RIBOSOMAL PROTEIN L26 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=37294|UniProtKB=P0CG41 P0CG41 CTAGE8 PTHR23158:SF57 MELANOMA INHIBITORY ACTIVITY-RELATED CTAGE FAMILY MEMBER 15-RELATED endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=2570|UniProtKB=P00167 P00167 CYB5A PTHR19359:SF126 CYTOCHROME B5 CYTOCHROME B5 electron transfer activity#GO:0009055;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 oxidoreductase#PC00176 HUMAN|HGNC=16609|UniProtKB=Q63ZY6 Q63ZY6 NSUN5P2 PTHR22807:SF67 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING NOL1/NOP2/SUN DOMAIN FAMILY MEMBER 5B-RELATED cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=33902|UniProtKB=Q3LI83 Q3LI83 KRTAP24-1 PTHR23260:SF2 KERATIN ASSOCIATED PROTEIN 3-3-RELATED KERATIN-ASSOCIATED PROTEIN 24-1 HUMAN|HGNC=34493|UniProtKB=A6NHQ4 A6NHQ4 EPOP PTHR23187:SF1 FLJ44216 PROTEIN-RELATED ELONGIN BC AND POLYCOMB REPRESSIVE COMPLEX 2-ASSOCIATED PROTEIN cellular developmental process#GO:0048869;system development#GO:0048731;cell differentiation#GO:0030154;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;cell fate commitment#GO:0045165;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399 HUMAN|HGNC=27380|UniProtKB=Q5U4P2 Q5U4P2 ASPHD1 PTHR46332:SF1 ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 1 hydroxylase#PC00122 HUMAN|HGNC=24270|UniProtKB=Q9H2P9 Q9H2P9 DPH5 PTHR10882:SF0 DIPHTHINE SYNTHASE DIPHTHINE METHYL ESTER SYNTHASE methyltransferase#PC00155 HUMAN|HGNC=29383|UniProtKB=Q8NCY6 Q8NCY6 MSANTD4 PTHR21732:SF0 MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 4 MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=12105|UniProtKB=A0A0B4J245 A0A0B4J245 TRAV12-1 PTHR19343:SF18 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 12-1 HUMAN|HGNC=13138|UniProtKB=Q9UC07 Q9UC07 ZNF69 PTHR24381:SF244 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 20-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13077|UniProtKB=Q8N7M2 Q8N7M2 ZNF283 PTHR24377:SF63 IP01015P-RELATED ZINC FINGER PROTEIN 283 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=20308|UniProtKB=Q5W0B1 Q5W0B1 OBI1 PTHR14609:SF1 RING FINGER PROTEIN 219 ORC UBIQUITIN LIGASE 1 HUMAN|HGNC=4940|UniProtKB=P04440 P04440 HLA-DPB1 PTHR19944:SF46 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DP BETA 1 CHAIN major histocompatibility complex protein#PC00149 HUMAN|HGNC=1755|UniProtKB=O75309 O75309 CDH16 PTHR24028:SF1 CADHERIN-87A CADHERIN-16 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|Gene=YM006_HUMAN|UniProtKB=Q9H521 Q9H521 - PTHR22988:SF72 MYOTONIC DYSTROPHY S/T KINASE-RELATED NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;actomyosin structure organization#GO:0031032;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;actin cytoskeleton organization#GO:0030036;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=536|UniProtKB=P27216 P27216 ANXA13 PTHR10502:SF175 ANNEXIN ANNEXIN A13 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 calcium-binding protein#PC00060 HUMAN|HGNC=4227|UniProtKB=P50395 P50395 GDI2 PTHR11787:SF1 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR BETA GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 G-protein modulator#PC00022 HUMAN|HGNC=25488|UniProtKB=Q9NW97 Q9NW97 TMEM51 PTHR16015:SF0 TRANSMEMBRANE PROTEIN 51 TRANSMEMBRANE PROTEIN 51 HUMAN|HGNC=32302|UniProtKB=P63133 P63133 ERVK-8 PTHR41694:SF4 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 10 POL PROTEIN-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 viral or transposable element protein#PC00237 HUMAN|HGNC=2873|UniProtKB=P00387 P00387 CYB5R3 PTHR19370:SF121 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE 3 nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 reductase#PC00198 HUMAN|HGNC=13635|UniProtKB=Q9BX97 Q9BX97 PLVAP PTHR21687:SF5 PLASMALEMMA VESICLE-ASSOCIATED PROTEIN PLASMALEMMA VESICLE-ASSOCIATED PROTEIN HUMAN|HGNC=17894|UniProtKB=Q14966 Q14966 ZNF638 PTHR15592:SF1 MATRIN 3/NUCLEAR PROTEIN 220-RELATED ZINC FINGER PROTEIN 638 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12902|UniProtKB=P17014 P17014 ZNF12 PTHR24377:SF797 IP01015P-RELATED ZINC FINGER PROTEIN 12 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=15093|UniProtKB=Q8NGT5 Q8NGT5 OR9A2 PTHR24242:SF248 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 9A2 G-protein coupled receptor#PC00021 HUMAN|HGNC=6451|UniProtKB=Q14525 Q14525 KRT33B PTHR23239:SF99 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA3-II HUMAN|HGNC=11774|UniProtKB=Q03167 Q03167 TGFBR3 PTHR14002:SF7 ENDOGLIN/TGF-BETA RECEPTOR TYPE III TRANSFORMING GROWTH FACTOR BETA RECEPTOR TYPE 3 cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>TBRIII#P06806 HUMAN|HGNC=43444|UniProtKB=P0CAP1 P0CAP1 MYZAP PTHR23171:SF2 GDOWN1 MYOCARDIAL ZONULA ADHERENS PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 HUMAN|HGNC=15299|UniProtKB=Q8NH69 Q8NH69 OR5W2 PTHR26452:SF824 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5W2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=9558|UniProtKB=Q9UNM6 Q9UNM6 PSMD13 PTHR10539:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 cellular component biogenesis#GO:0044085;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein-containing complex assembly#GO:0065003;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;proteasome assembly#GO:0043248;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;cellular protein catabolic process#GO:0044257;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227 protease#PC00190 Parkinson disease#P00049>19S proteasome#P01209;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 HUMAN|HGNC=22946|UniProtKB=Q96FL9 Q96FL9 GALNT14 PTHR11675:SF8 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 14 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=15508|UniProtKB=Q9Y606 Q9Y606 PUS1 PTHR11142:SF4 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE SYNTHASE A isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 lyase#PC00144 HUMAN|HGNC=13182|UniProtKB=Q9P1U0 Q9P1U0 POLR1H PTHR11239:SF14 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=29233|UniProtKB=Q7Z434 Q7Z434 MAVS PTHR21446:SF6 DUF3504 DOMAIN-CONTAINING PROTEIN MITOCHONDRIAL ANTIVIRAL-SIGNALING PROTEIN HUMAN|HGNC=130|UniProtKB=P62736 P62736 ACTA2 PTHR11937:SF445 ACTIN ACTIN, AORTIC SMOOTH MUSCLE actin and actin related protein#PC00039 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 HUMAN|HGNC=25574|UniProtKB=Q9BVG3 Q9BVG3 TRIM62 PTHR24103:SF573 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM62 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=28212|UniProtKB=Q9BRA0 Q9BRA0 NAA38 PTHR10701:SF17 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNIT RNA splicing factor#PC00148 HUMAN|HGNC=7103|UniProtKB=P30301 P30301 MIP PTHR19139:SF39 AQUAPORIN TRANSPORTER LENS FIBER MAJOR INTRINSIC PROTEIN inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=23508|UniProtKB=Q6ZVD7 Q6ZVD7 STOX1 PTHR22437:SF1 WINGED HELIX DOMAIN-CONTAINING PROTEIN STORKHEAD-BOX PROTEIN 1 HUMAN|HGNC=2964|UniProtKB=Q13409 Q13409 DYNC1I2 PTHR12442:SF37 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 2 dynein heavy chain binding#GO:0045504;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;transport along microtubule#GO:0010970 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=20694|UniProtKB=Q99865 Q99865 SPIN2A PTHR10405:SF13 SPINDLIN SPINDLIN-2A-RELATED protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11571|UniProtKB=Q13148 Q13148 TARDBP PTHR48033:SF9 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN TAR DNA-BINDING PROTEIN 43 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=21222|UniProtKB=Q8TF01 Q8TF01 PNISR PTHR31518:SF3 ARGININE/SERINE-RICH PROTEIN PNISR ARGININE/SERINE-RICH PROTEIN PNISR HUMAN|HGNC=14050|UniProtKB=P82912 P82912 MRPS11 PTHR11759:SF3 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 28S RIBOSOMAL PROTEIN S11, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;rRNA binding#GO:0019843 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;organelle organization#GO:0006996;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;translational elongation#GO:0006414;ribosomal small subunit biogenesis#GO:0042274;cellular amide metabolic process#GO:0043603 ribosomal protein#PC00202 HUMAN|HGNC=26481|UniProtKB=Q68D06 Q68D06 SLFN13 PTHR12155:SF43 SCHLAFEN SCHLAFEN FAMILY MEMBER 13 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252 HUMAN|HGNC=25206|UniProtKB=Q8WV99 Q8WV99 ZFAND2B PTHR14677:SF13 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE ZINC FINGER PROTEIN 2B RNA metabolism protein#PC00031 HUMAN|HGNC=16869|UniProtKB=Q7L311 Q7L311 ARMCX2 PTHR15712:SF9 ARMADILLO REPEAT CONTAINING PROTEIN ARMADILLO REPEAT-CONTAINING X-LINKED PROTEIN 2 HUMAN|HGNC=33105|UniProtKB=Q5VIY5 Q5VIY5 ZNF468 PTHR24377:SF875 IP01015P-RELATED ZINC FINGER PROTEIN 468 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12724|UniProtKB=P04004 P04004 VTN PTHR22917:SF3 HEMOPEXIN DOMAIN-CONTAINING PROTEIN VITRONECTIN HUMAN|HGNC=12420|UniProtKB=P49411 P49411 TUFM PTHR43721:SF22 ELONGATION FACTOR TU-RELATED ELONGATION FACTOR TU, MITOCHONDRIAL nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation elongation factor#PC00222 HUMAN|HGNC=5164|UniProtKB=Q9Y251 Q9Y251 HPSE PTHR46145:SF3 HEPARANASE HEPARANASE extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110 HUMAN|HGNC=26586|UniProtKB=Q8N2A0 Q8N2A0 LINC00269 PTHR12138:SF124 PRIMATE-EXPANDED PROTEIN FAMILY SUBFAMILY NOT NAMED HUMAN|HGNC=6361|UniProtKB=Q9UKR3 Q9UKR3 KLK13 PTHR24271:SF3 KALLIKREIN-RELATED KALLIKREIN-13 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=18311|UniProtKB=Q9BS26 Q9BS26 ERP44 PTHR46295:SF1 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 HUMAN|HGNC=3120|UniProtKB=O75461 O75461 E2F6 PTHR12081:SF19 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=18472|UniProtKB=Q9C0B5 Q9C0B5 ZDHHC5 PTHR12349:SF3 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 PALMITOYLTRANSFERASE ZDHHC5 transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;protein acylation#GO:0043543;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;lipoprotein metabolic process#GO:0042157;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=14264|UniProtKB=Q9NY12 Q9NY12 GAR1 PTHR23237:SF10 NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1 H/ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 small nucleolar ribonucleoprotein complex#GO:0005732;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=11721|UniProtKB=Q96PL2 Q96PL2 TECTB PTHR14002:SF13 ENDOGLIN/TGF-BETA RECEPTOR TYPE III BETA-TECTORIN transmembrane signal receptor#PC00197 HUMAN|HGNC=33238|UniProtKB=Q6YP21 Q6YP21 KYAT3 PTHR43807:SF6 FI04487P KYNURENINE--OXOGLUTARATE TRANSAMINASE 3 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transaminase#PC00216 HUMAN|HGNC=26894|UniProtKB=Q4KMQ1 Q4KMQ1 TPRN PTHR21685:SF1 TON-B BOX DOMAIN TAPERIN HUMAN|HGNC=11931|UniProtKB=O95150 O95150 TNFSF15 PTHR11471:SF24 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15 HUMAN|HGNC=4719|UniProtKB=P16401 P16401 H1-5 PTHR11467:SF24 HISTONE H1 HISTONE H1.5 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of chromatin silencing#GO:0031935;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of chromatin silencing#GO:0031936;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of chromatin organization#GO:1902275;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;chromosome condensation#GO:0030261;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of DNA recombination#GO:0000018;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone#PC00118 HUMAN|HGNC=12950|UniProtKB=Q15637 Q15637 SF1 PTHR11208:SF45 RNA-BINDING PROTEIN RELATED SPLICING FACTOR 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA splicing factor#PC00148 HUMAN|HGNC=28453|UniProtKB=Q8IVV7 Q8IVV7 GID4 PTHR15898:SF13 UNCHARACTERIZED GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=25087|UniProtKB=Q8IWE2 Q8IWE2 FAM114A1 PTHR12842:SF4 FI01459P PROTEIN NOXP20 HUMAN|HGNC=11354|UniProtKB=Q8WVM7 Q8WVM7 STAG1 PTHR11199:SF6 STROMAL ANTIGEN COHESIN SUBUNIT SA-1-RELATED binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;chromatin#GO:0000785;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=30373|UniProtKB=Q6XZF7 Q6XZF7 DNMBP PTHR22834:SF19 NUCLEAR FUSION PROTEIN FUS2 DYNAMIN-BINDING PROTEIN Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 HUMAN|HGNC=8648|UniProtKB=Q15366 Q15366 PCBP2 PTHR10288:SF97 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=23466|UniProtKB=Q5VW22 Q5VW22 AGAP6 PTHR45819:SF7 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 4-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=9986|UniProtKB=P48382 P48382 RFX5 PTHR12619:SF18 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=15629|UniProtKB=Q9NY97 Q9NY97 B3GNT2 PTHR11214:SF25 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 2 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;cellular polysaccharide biosynthetic process#GO:0033692;cellular polysaccharide metabolic process#GO:0044264;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=15136|UniProtKB=Q8NGI7 Q8NGI7 OR10V1 PTHR26452:SF263 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10V1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=19071|UniProtKB=Q86V81 Q86V81 ALYREF PTHR19965:SF82 RNA AND EXPORT FACTOR BINDING PROTEIN THO COMPLEX SUBUNIT 4 RNA metabolism protein#PC00031 HUMAN|HGNC=13606|UniProtKB=Q9Y2K7 Q9Y2K7 KDM2A PTHR23123:SF3 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 2A molecular function regulator#GO:0098772;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;demethylation#GO:0070988;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein demethylation#GO:0006482;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=21408|UniProtKB=Q8IYS1 Q8IYS1 PM20D2 PTHR30575:SF0 PEPTIDASE M20 PEPTIDASE M20 DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;peptidase activity#GO:0008233;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;pteridine-containing compound metabolic process#GO:0042558;heterocycle catabolic process#GO:0046700;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular nitrogen compound catabolic process#GO:0044270;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=8652|UniProtKB=P57723 P57723 PCBP4 PTHR10288:SF166 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=33893|UniProtKB=Q6S8J7 Q6S8J7 POTEA PTHR24118:SF78 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER A membrane traffic protein#PC00150 HUMAN|HGNC=23487|UniProtKB=Q9BXS1 Q9BXS1 IDI2 PTHR10885:SF1 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE 2 isomerase activity#GO:0016853;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 isomerase#PC00135 Cholesterol biosynthesis#P00014>Isopentenyl diphosphate delta-isomerase#P00495 HUMAN|HGNC=17579|UniProtKB=Q14849 Q14849 STARD3 PTHR46121:SF2 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STAR-RELATED LIPID TRANSFER PROTEIN 3 HUMAN|HGNC=12625|UniProtKB=Q96RU2 Q96RU2 USP28 PTHR24006:SF678 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 28 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of biological process#GO:0050789;cell cycle checkpoint#GO:0000075;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;DNA damage checkpoint#GO:0000077;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=24430|UniProtKB=Q01546 Q01546 KRT76 PTHR45616:SF29 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 2 ORAL HUMAN|HGNC=26430|UniProtKB=Q70UQ0 Q70UQ0 IKBIP PTHR21734:SF10 INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE-INTERACTING PROTEIN HUMAN|HGNC=19979|UniProtKB=Q9HBH5 Q9HBH5 RDH14 PTHR24320:SF189 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 14 dehydrogenase#PC00092 HUMAN|HGNC=7995|UniProtKB=O43847 O43847 NRDC PTHR43690:SF18 NARDILYSIN NARDILYSIN metalloprotease#PC00153 HUMAN|HGNC=5138|UniProtKB=P09016 P09016 HOXD4 PTHR45771:SF5 HOMEOTIC PROTEIN DEFORMED HOMEOBOX PROTEIN HOX-D4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=30072|UniProtKB=Q8N6Q3 Q8N6Q3 CD177 PTHR16529:SF8 CD177 ANTIGEN CD177 ANTIGEN plasma membrane raft#GO:0044853;anchored component of plasma membrane#GO:0046658;intrinsic component of membrane#GO:0031224;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;membrane raft#GO:0045121;anchored component of membrane#GO:0031225;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane region#GO:0098589;membrane microdomain#GO:0098857;plasma membrane#GO:0005886;whole membrane#GO:0098805 HUMAN|HGNC=11019|UniProtKB=Q06495 Q06495 SLC34A1 PTHR10010:SF21 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2A secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;solute:cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;inorganic anion transport#GO:0015698 secondary carrier transporter#PC00258 HUMAN|HGNC=7884|UniProtKB=Q99466 Q99466 NOTCH4 PTHR24044:SF420 NOTCH LIGAND FAMILY MEMBER NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 4 Notch signaling pathway#P00045>Notch#P01099;Angiogenesis#P00005>Notch#P00255;Notch signaling pathway#P00045>NIct#P01119;Alzheimer disease-presenilin pathway#P00004>Notch N-terminal fragment#P00171;Notch signaling pathway#P00045>NIcs#P01120;Notch signaling pathway#P00045>Ntm#P01114;Alzheimer disease-presenilin pathway#P00004>Notch C-terminal fragment#P00120;Alzheimer disease-presenilin pathway#P00004>NICD#P00122;Alzheimer disease-presenilin pathway#P00004>Notch#P00176;Alzheimer disease-presenilin pathway#P00004>Notch fragment#P00154;Alzheimer disease-presenilin pathway#P00004>Notch transmembrane fragment#P00135;Alzheimer disease-presenilin pathway#P00004>Notch extracellular fragment#P00179 HUMAN|HGNC=3165|UniProtKB=P21453 P21453 S1PR1 PTHR22750:SF16 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;vasculature development#GO:0001944;intracellular signal transduction#GO:0035556;signaling#GO:0023052;metabolic process#GO:0008152;activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;tube development#GO:0035295;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=25513|UniProtKB=Q9H9Y4 Q9H9Y4 GPN2 PTHR21231:SF3 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 2 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 small GTPase#PC00208 HUMAN|HGNC=6606|UniProtKB=Q8N423 Q8N423 LILRB2 PTHR11738:SF170 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 3-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|Ensembl=ENSG00000281106|UniProtKB=A0A1B0GTI8 A0A1B0GTI8 TMEM272 PTHR33444:SF7 SI:DKEY-19B23.12-RELATED TRANSMEMBRANE PROTEIN 272 HUMAN|HGNC=4807|UniProtKB=O96004 O96004 HAND1 PTHR23349:SF3 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST HEART- AND NEURAL CREST DERIVATIVES-EXPRESSED PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=19353|UniProtKB=Q96ST3 Q96ST3 SIN3A PTHR12346:SF2 SIN3B-RELATED PAIRED AMPHIPATHIC HELIX PROTEIN SIN3A transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;molecular function regulator#GO:0098772;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>Sin3A#P00771;p53 pathway#P00059>Sin3#P04622 HUMAN|HGNC=26571|UniProtKB=Q5XG99 Q5XG99 LYSMD4 PTHR20932:SF7 LOC443603 PROTEIN-RELATED AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 4-RELATED HUMAN|HGNC=20|UniProtKB=P49588 P49588 AARS1 PTHR11777:SF36 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, CYTOPLASMIC amino acid binding#GO:0016597;hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;ligase activity#GO:0016874;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;organic acid binding#GO:0043177;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;cellular amide metabolic process#GO:0043603;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=18170|UniProtKB=P30085 P30085 CMPK1 PTHR23359:SF206 NUCLEOTIDE KINASE UMP-CMP KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;adenylate kinase activity#GO:0004017;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotide kinase#PC00172 De novo pyrimidine ribonucleotides biosythesis#P02740>Uridylate kinase#P02924;De novo purine biosynthesis#P02738>Adenylate kinase#P02896;Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153 HUMAN|HGNC=16253|UniProtKB=Q9NUV7 Q9NUV7 SPTLC3 PTHR13693:SF56 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 3 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transaminase#PC00216 HUMAN|HGNC=1044|UniProtKB=P21810 P21810 BGN PTHR45712:SF11 AGAP008170-PA BIGLYCAN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=11155|UniProtKB=P08579 P08579 SNRPB2 PTHR10501:SF61 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B'' nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;snRNA binding#GO:0017069;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;U1 snRNP#GO:0005685;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 mRNA splicing#P00058>U2#P01478 HUMAN|HGNC=24145|UniProtKB=Q96RP7 Q96RP7 GAL3ST4 PTHR14647:SF57 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 HUMAN|HGNC=3273|UniProtKB=O15372 O15372 EIF3H PTHR10410:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT H nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;RNA binding#GO:0003723;metallopeptidase activity#GO:0008237;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;small ribosomal subunit#GO:0015935;polysome#GO:0005844;ribosome#GO:0005840 translation initiation factor#PC00224 HUMAN|HGNC=37276|UniProtKB=A4D126 A4D126 CRPPA PTHR43015:SF1 D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transferase#PC00220 HUMAN|HGNC=2149|UniProtKB=Q16280 Q16280 CNGA2 PTHR45638:SF3 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED OLFACTORY CHANNEL cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;inorganic molecular entity transmembrane transporter activity#GO:0015318;nucleotide binding#GO:0000166;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;purine nucleotide binding#GO:0017076;gated channel activity#GO:0022836;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 ligand-gated ion channel#PC00141 HUMAN|HGNC=6737|UniProtKB=O75608 O75608 LYPLA1 PTHR10655:SF22 LYSOPHOSPHOLIPASE-RELATED ACYL-PROTEIN THIOESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;macromolecule deacylation#GO:0098732;protein deacylation#GO:0035601;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;lipoprotein metabolic process#GO:0042157;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phospholipase#PC00186 HUMAN|HGNC=7637|UniProtKB=P55209 P55209 NAP1L1 PTHR11875:SF145 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 1 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;organelle organization#GO:0006996;chromosome organization#GO:0051276;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=6530|UniProtKB=P09848 P09848 LCT PTHR10353:SF38 GLYCOSYL HYDROLASE LACTASE-PHLORIZIN HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosidase#PC00110 HUMAN|HGNC=26348|UniProtKB=Q8IYM1 Q8IYM1 SEPTIN12 PTHR18884:SF66 SEPTIN SEPTIN-12 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cell division#GO:0051301;cellular localization#GO:0051641;membrane fission#GO:0090148;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 HUMAN|HGNC=30511|UniProtKB=Q5BJH7 Q5BJH7 YIF1B PTHR14083:SF1 YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN PROTEIN YIF1B localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=9665|UniProtKB=P23467 P23467 PTPRB PTHR46957:SF2 CYTOKINE RECEPTOR RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE BETA cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 system development#GO:0048731;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;angiogenesis#GO:0001525;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;blood vessel development#GO:0001568;vasculature development#GO:0001944;multicellular organismal process#GO:0032501;anatomical structure formation involved in morphogenesis#GO:0048646 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VE-PTP#P00250 HUMAN|HGNC=26070|UniProtKB=Q9BVS5 Q9BVS5 TRMT61B PTHR12133:SF1 TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE, MITOCHONDRIAL tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA (adenine) methyltransferase activity#GO:0016426;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 RNA methyltransferase#PC00033 HUMAN|HGNC=28509|UniProtKB=Q8NDZ0 Q8NDZ0 BEND2 PTHR47305:SF1 BEN DOMAIN-CONTAINING PROTEIN 2 BEN DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=6878|UniProtKB=P31152 P31152 MAPK4 PTHR24055:SF25 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 4 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099 HUMAN|HGNC=16486|UniProtKB=O75689 O75689 ADAP1 PTHR46021:SF5 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=1552|UniProtKB=Q14781 Q14781 CBX2 PTHR46860:SF1 CHROMOBOX PROTEIN HOMOLOG 2 CHROMOBOX PROTEIN HOMOLOG 2 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=26397|UniProtKB=Q6UWN5 Q6UWN5 LYPD5 PTHR10624:SF9 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR-RELATED LY6/PLAUR DOMAIN-CONTAINING PROTEIN 5 extracellular matrix binding#GO:0050840;protein binding#GO:0005515;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=17929|UniProtKB=Q8N5Z0 Q8N5Z0 AADAT PTHR42790:SF3 AMINOTRANSFERASE KYNURENINE/ALPHA-AMINOADIPATE AMINOTRANSFERASE, MITOCHONDRIAL transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid metabolic process#GO:0006520;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transaminase#PC00216 HUMAN|HGNC=12381|UniProtKB=Q01534 Q01534 TSPY1 PTHR11875:SF12 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED PROTEIN 1-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=2705|UniProtKB=P07585 P07585 DCN PTHR45712:SF14 AGAP008170-PA DECORIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=30681|UniProtKB=Q8N5C8 Q8N5C8 TAB3 PTHR46253:SF3 TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 3 membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 HUMAN|HGNC=14908|UniProtKB=Q9H3S3 Q9H3S3 TMPRSS5 PTHR24253:SF70 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 5 serine protease#PC00203 HUMAN|HGNC=1960|UniProtKB=P36544 P36544 CHRNA7 PTHR18945:SF890 NEUROTRANSMITTER GATED ION CHANNEL CHRNA7-FAM7A FUSION PROTEIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=16653|UniProtKB=Q96GC5 Q96GC5 MRPL48 PTHR13473:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L48 39S RIBOSOMAL PROTEIN L48, MITOCHONDRIAL membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=41910|UniProtKB=P0CW27 P0CW27 CCDC166 PTHR14845:SF4 COILED-COIL DOMAIN-CONTAINING 166 COILED-COIL DOMAIN-CONTAINING PROTEIN 166 HUMAN|HGNC=2772|UniProtKB=O00273 O00273 DFFA PTHR12306:SF16 CELL DEATH ACTIVATOR CIDE CIDE-N DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=25941|UniProtKB=Q6N021 Q6N021 TET2 PTHR23358:SF3 UNCHARACTERIZED METHYLCYTOSINE DIOXYGENASE TET2 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;demethylation#GO:0070988;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;hematopoietic or lymphoid organ development#GO:0048534;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;myeloid cell differentiation#GO:0030099;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;oxidative demethylation#GO:0070989;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4017|UniProtKB=P51993 P51993 FUT6 PTHR11929:SF227 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE FUT6 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111 HUMAN|HGNC=25457|UniProtKB=Q8N3F0 Q8N3F0 MTURN PTHR32008:SF2 MATURIN MATURIN HUMAN|HGNC=3239|UniProtKB=P11161 P11161 EGR2 PTHR23235:SF54 KRUEPPEL-LIKE TRANSCRIPTION FACTOR E3 SUMO-PROTEIN LIGASE EGR2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=22941|UniProtKB=Q7RTR0 Q7RTR0 NLRP9 PTHR45690:SF13 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 9 HUMAN|HGNC=11722|UniProtKB=Q10587 Q10587 TEF PTHR11988:SF24 THYROTROPH EMBRYONIC FACTOR RELATED THYROTROPH EMBRYONIC FACTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=2452|UniProtKB=P48730 P48730 CSNK1D PTHR11909:SF459 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM DELTA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;membrane organization#GO:0061024;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;vesicle organization#GO:0016050;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;CCKR signaling map#P06959>CK1delta/epsilon#P07089;Circadian clock system#P00015>Casein kinase I#P00502;Parkinson disease#P00049>Casein kinase I#P01242 HUMAN|HGNC=9928|UniProtKB=P62877 P62877 RBX1 PTHR11210:SF2 RING BOX E3 UBIQUITIN-PROTEIN LIGASE RBX1 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=28775|UniProtKB=Q9BVX2 Q9BVX2 TMEM106C PTHR28556:SF5 TRANSMEMBRANE PROTEIN 106B TRANSMEMBRANE PROTEIN 106C HUMAN|HGNC=25694|UniProtKB=Q8TC07 Q8TC07 TBC1D15 PTHR22957:SF300 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 15 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=4371|UniProtKB=Q9UKD1 Q9UKD1 GMEB2 PTHR10417:SF2 GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=33737|UniProtKB=Q5HYW2 Q5HYW2 NHSL2 PTHR23039:SF2 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 2 cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 HUMAN|HGNC=11692|UniProtKB=P57738 P57738 TCTA PTHR32267:SF2 T-CELL LEUKEMIA TRANSLOCATION-ALTERED GENE PROTEIN T-CELL LEUKEMIA TRANSLOCATION-ALTERED GENE PROTEIN HUMAN|HGNC=26145|UniProtKB=Q9H6V9 Q9H6V9 LDAH PTHR13390:SF0 LIPASE LIPID DROPLET-ASSOCIATED HYDROLASE biological regulation#GO:0065007;localization#GO:0051179;lipid localization#GO:0010876;lipid storage#GO:0019915;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;maintenance of location#GO:0051235 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 lipase#PC00143 HUMAN|HGNC=9083|UniProtKB=O60568 O60568 PLOD3 PTHR10730:SF7 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER MULTIFUNCTIONAL PROCOLLAGEN LYSINE HYDROXYLASE AND GLYCOSYLTRANSFERASE LH3 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;transferase activity, transferring glycosyl groups#GO:0016757;glucosyltransferase activity#GO:0046527;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=3490|UniProtKB=P50549 P50549 ETV1 PTHR11849:SF196 ETS ETS TRANSLOCATION VARIANT 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=3050|UniProtKB=P32926 P32926 DSG3 PTHR24025:SF3 DESMOGLEIN FAMILY MEMBER DESMOGLEIN-3 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cadherin#PC00057 HUMAN|HGNC=16932|UniProtKB=O76041 O76041 NEBL PTHR11039:SF48 NEBULIN NEBULETTE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;heart development#GO:0007507;muscle cell differentiation#GO:0042692;cardiac muscle cell differentiation#GO:0055007;animal organ development#GO:0048513;developmental process#GO:0032502;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;system development#GO:0048731;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;striated muscle tissue development#GO:0014706;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;circulatory system development#GO:0072359;cardiac muscle tissue development#GO:0048738;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cardiac muscle cell development#GO:0055013;muscle tissue development#GO:0060537;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cardiocyte differentiation#GO:0035051;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;Z disc#GO:0030018;intracellular#GO:0005622;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229;I band#GO:0031674 HUMAN|HGNC=16165|UniProtKB=Q9H410 Q9H410 DSN1 PTHR14778:SF2 KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;mitotic sister chromatid segregation#GO:0000070 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;condensed nuclear chromosome kinetochore#GO:0000778;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 HUMAN|HGNC=17402|UniProtKB=Q96DE9 Q96DE9 EOLA2 PTHR31666:SF0 PROTEIN CXORF40A-RELATED PROTEIN EOLA1-RELATED HUMAN|HGNC=8874|UniProtKB=Q16875 Q16875 PFKFB3 PTHR10606:SF41 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578 carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 carbohydrate phosphatase#PC00066 HUMAN|HGNC=17944|UniProtKB=Q9NQT5 Q9NQT5 EXOSC3 PTHR21321:SF1 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP40 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;mRNA catabolic process#GO:0006402;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;snRNA processing#GO:0016180;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;maturation of 5.8S rRNA#GO:0000460;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;cleavage involved in rRNA processing#GO:0000469;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;snRNA metabolic process#GO:0016073;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;rRNA metabolic process#GO:0016072;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 protein-containing complex#GO:0032991;exosome (RNase complex)#GO:0000178;catalytic complex#GO:1902494;intracellular#GO:0005622 RNA processing factor#PC00147 HUMAN|HGNC=22316|UniProtKB=Q8NHG8 Q8NHG8 ZNRF2 PTHR46661:SF3 E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZNRF2 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=30060|UniProtKB=Q15155 Q15155 NOMO1 PTHR23303:SF14 CARBOXYPEPTIDASE REGULATORY REGION-CONTAINING NODAL MODULATOR 1-RELATED cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=224|UniProtKB=Q9UP79 Q9UP79 ADAMTS8 PTHR13723:SF41 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 8 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=30358|UniProtKB=A0AV96 A0AV96 RBM47 PTHR21245:SF6 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 47 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=14359|UniProtKB=Q9BZI1 Q9BZI1 IRX2 PTHR11211:SF15 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=18709|UniProtKB=Q8WWL7 Q8WWL7 CCNB3 PTHR10177:SF214 CYCLINS G2/MITOTIC-SPECIFIC CYCLIN-B3 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 HUMAN|HGNC=28351|UniProtKB=Q9BQE6 Q9BQE6 LBHD1 PTHR14987:SF1 PROTEIN LBH-RELATED LBH DOMAIN-CONTAINING PROTEIN 1 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=13307|UniProtKB=Q9H1C0 Q9H1C0 LPAR5 PTHR24234:SF6 LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 5 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;behavior#GO:0007610;positive regulation of molecular function#GO:0044093;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 G-protein coupled receptor#PC00021 HUMAN|HGNC=8950|UniProtKB=P35237 P35237 SERPINB6 PTHR11461:SF204 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B6 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=9894|UniProtKB=Q08999 Q08999 RBL2 PTHR13742:SF8 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RETINOBLASTOMA-LIKE PROTEIN 2 nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;activating transcription factor binding#GO:0033613;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;developmental process#GO:0032502;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;G1/S transition of mitotic cell cycle#GO:0000082;cell differentiation#GO:0030154;negative regulation of mitotic cell cycle phase transition#GO:1901991;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;regulation of G1/S transition of mitotic cell cycle#GO:2000045;negative regulation of cellular process#GO:0048523;negative regulation of G1/S transition of mitotic cell cycle#GO:2000134;cellular developmental process#GO:0048869;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G1/S phase transition#GO:1902806 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromatin#GO:0000785;chromosome#GO:0005694;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=9674|UniProtKB=Q15262 Q15262 PTPRK PTHR19134:SF209 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE KAPPA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=10604|UniProtKB=O43819 O43819 SCO2 PTHR12151:SF2 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER PROTEIN SCO2 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 oxidase#PC00175 HUMAN|HGNC=20329|UniProtKB=Q6UWJ1 Q6UWJ1 TMCO3 PTHR16254:SF14 POTASSIUM/PROTON ANTIPORTER-RELATED TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=17116|UniProtKB=Q8NEC5 Q8NEC5 CATSPER1 PTHR47193:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 male gamete generation#GO:0048232;regulation of microtubule-based process#GO:0032886;regulation of locomotion#GO:0040012;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;regulation of localization#GO:0032879;sperm motility#GO:0097722;cation transport#GO:0006812;cilium movement involved in cell motility#GO:0060294;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;spermatogenesis#GO:0007283;divalent inorganic cation transport#GO:0072511;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;regulation of cellular component movement#GO:0051270;gamete generation#GO:0007276;metal ion transport#GO:0030001;regulation of cell motility#GO:2000145;multicellular organism reproduction#GO:0032504;ion transport#GO:0006811;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;multi-organism process#GO:0051704;cilium movement#GO:0003341;localization#GO:0051179;developmental process involved in reproduction#GO:0003006;cilium-dependent cell motility#GO:0060285;reproduction#GO:0000003;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;voltage-gated calcium channel complex#GO:0005891;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=216|UniProtKB=Q13443 Q13443 ADAM9 PTHR11905:SF136 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 9 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153 Alzheimer disease-amyloid secretase pathway#P00003>MDC9#P00090 HUMAN|HGNC=26946|UniProtKB=Q96HJ9 Q96HJ9 FMC1 PTHR31716:SF1 PROTEIN FMC1 HOMOLOG PROTEIN FMC1 HOMOLOG cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=19660|UniProtKB=Q6YBV0 Q6YBV0 SLC36A4 PTHR22950:SF190 AMINO ACID TRANSPORTER PROTON-COUPLED AMINO ACID TRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;alanine transport#GO:0032328;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 amino acid transporter#PC00046 HUMAN|HGNC=4330|UniProtKB=P35754 P35754 GLRX PTHR46185:SF1 GLUTAREDOXIN-1 GLUTAREDOXIN-1 oxidoreductase#PC00176 HUMAN|HGNC=10349|UniProtKB=P63173 P63173 RPL38 PTHR10965:SF0 60S RIBOSOMAL PROTEIN L38 60S RIBOSOMAL PROTEIN L38 ribosomal protein#PC00202 HUMAN|HGNC=14912|UniProtKB=Q9NYW4 Q9NYW4 TAS2R5 PTHR11394:SF8 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=21301|UniProtKB=Q5SQH8 Q5SQH8 C6orf136 PTHR31094:SF2 RIKEN CDNA 2310061I04 GENE RIKEN CDNA 2310061I04 GENE HUMAN|HGNC=17726|UniProtKB=Q8WWF5 Q8WWF5 ZNRF4 PTHR22765:SF347 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ZNRF4 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 negative regulation of biological process#GO:0048519;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=3183|UniProtKB=Q8IXK0 Q8IXK0 PHC2 PTHR12247:SF86 POLYCOMB GROUP PROTEIN POLYHOMEOTIC-LIKE PROTEIN 2 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=11599|UniProtKB=Q9UL17 Q9UL17 TBX21 PTHR11267:SF125 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX21 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 specification of symmetry#GO:0009799;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;heart looping#GO:0001947;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;heart development#GO:0007507;embryonic heart tube development#GO:0035050;determination of heart left/right asymmetry#GO:0061371;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;determination of bilateral symmetry#GO:0009855;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;determination of left/right symmetry#GO:0007368;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;cell motility#GO:0048870;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;lymphocyte migration#GO:0072676;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;cell migration#GO:0016477;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=7432|UniProtKB=P11586 P11586 MTHFD1 PTHR48099:SF1 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;pteridine-containing compound metabolic process#GO:0042558;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=19074|UniProtKB=Q13769 Q13769 THOC5 PTHR13375:SF3 FMS INTERACTING PROTEIN THO COMPLEX SUBUNIT 5 HOMOLOG RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;positive regulation of biological process#GO:0048518;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;nuclear export#GO:0051168;regulation of cellular process#GO:0050794;protein transport#GO:0015031;aromatic compound biosynthetic process#GO:0019438;intracellular transport#GO:0046907;regulation of metabolic process#GO:0019222;protein-containing complex localization#GO:0031503;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nucleic acid transport#GO:0050657;biosynthetic process#GO:0009058;ribonucleoprotein complex export from nucleus#GO:0071426;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription, elongation#GO:0032784;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;protein export from nucleus#GO:0006611;regulation of macromolecule biosynthetic process#GO:0010556;DNA-templated transcription, elongation#GO:0006354;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;mRNA export from nucleus#GO:0006406;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;organic cyclic compound biosynthetic process#GO:1901362;mRNA transport#GO:0051028;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;nucleocytoplasmic transport#GO:0006913;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound transport#GO:0015931;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;RNA export from nucleus#GO:0006405;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;THO complex#GO:0000347;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14453|UniProtKB=Q9P0M6 Q9P0M6 MACROH2A2 PTHR23430:SF37 HISTONE H2A CORE HISTONE MACRO-H2A.2 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=9531|UniProtKB=P25787 P25787 PSMA2 PTHR11599:SF16 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-2 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome core complex, alpha-subunit complex#GO:0019773;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=2941|UniProtKB=Q8IVF4 Q8IVF4 DNAH10 PTHR10676:SF343 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN 10, AXONEMAL pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=26009|UniProtKB=Q8TE82 Q8TE82 SH3TC1 PTHR22647:SF3 SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1 HUMAN|HGNC=609|UniProtKB=P02655 P02655 APOC2 PTHR16566:SF0 APOLIPOPROTEIN C-II APOLIPOPROTEIN C-II apolipoprotein#PC00052 HUMAN|HGNC=19910|UniProtKB=Q9H6R4 Q9H6R4 NOL6 PTHR17972:SF0 NUCLEOLAR RNA-ASSOCIATED PROTEIN NUCLEOLAR PROTEIN 6 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;transport#GO:0006810;RNA processing#GO:0006396;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;ribosome biogenesis#GO:0042254;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;rRNA metabolic process#GO:0016072;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;ribonucleoprotein complex biogenesis#GO:0022613;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 HUMAN|HGNC=21078|UniProtKB=Q7Z4H3 Q7Z4H3 HDDC2 PTHR11845:SF13 UNCHARACTERIZED 5'-DEOXYNUCLEOTIDASE HDDC2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=8172|UniProtKB=Q9Y4A9 Q9Y4A9 OR10H1 PTHR24247:SF122 5-HYDROXYTRYPTAMINE RECEPTOR OLFACTORY RECEPTOR 10H1-RELATED cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=12703|UniProtKB=O76090 O76090 BEST1 PTHR10736:SF4 BESTROPHIN BESTROPHIN-1 ion channel#PC00133 HUMAN|HGNC=430|UniProtKB=O75342 O75342 ALOX12B PTHR11771:SF40 LIPOXYGENASE ARACHIDONATE 12-LIPOXYGENASE, 12R-TYPE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;oxidation-reduction process#GO:0055114;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular#GO:0005622 oxygenase#PC00177 HUMAN|HGNC=32443|UniProtKB=Q8N967 Q8N967 LRTM2 PTHR45836:SF16 SLIT HOMOLOG LEUCINE-RICH REPEAT AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 carbohydrate derivative binding#GO:0097367;binding#GO:0005488;heparin binding#GO:0008201;protein binding#GO:0005515;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 HUMAN|HGNC=2279|UniProtKB=Q02221 Q02221 COX6A2 PTHR11504:SF1 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT 6A2, MITOCHONDRIAL inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;molecular function regulator#GO:0098772;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;oxidoreductase activity#GO:0016491;enzyme regulator activity#GO:0030234 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;aerobic electron transport chain#GO:0019646;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277 oxidase#PC00175 HUMAN|HGNC=4039|UniProtKB=Q9ULW2 Q9ULW2 FZD10 PTHR11309:SF86 FRIZZLED FRIZZLED-10 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 HUMAN|HGNC=19964|UniProtKB=Q7L8A9 Q7L8A9 VASH1 PTHR15750:SF5 VASOHIBIN-1-LIKE ISOFORM X2 TUBULINYL-TYR CARBOXYPEPTIDASE 1 regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;regulation of developmental process#GO:0050793;tube morphogenesis#GO:0035239;regulation of vasculature development#GO:1901342;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;vasculature development#GO:0001944;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=8699|UniProtKB=O60330 O60330 PCDHGA12 PTHR24028:SF227 CADHERIN-87A PROTOCADHERIN GAMMA-A12 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=23020|UniProtKB=Q8WU68 Q8WU68 U2AF1L4 PTHR12620:SF3 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT SPLICING FACTOR U2AF 26 KDA SUBUNIT nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=17956|UniProtKB=Q9BV38 Q9BV38 WDR18 PTHR18763:SF0 WD-REPEAT PROTEIN 18 WD REPEAT-CONTAINING PROTEIN 18 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;regulation of macromolecule biosynthetic process#GO:0010556;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;DNA biosynthetic process#GO:0071897;rRNA metabolic process#GO:0016072;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;pre-replicative complex#GO:0036387;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=34301|UniProtKB=Q6ZQY2 Q6ZQY2 LRRC74B PTHR24114:SF37 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74B HUMAN|HGNC=18441|UniProtKB=Q8TDW4 Q8TDW4 ST7L PTHR12745:SF4 SUPPRESSION OF TUMORIGENICITY 7 SUPPRESSOR OF TUMORIGENICITY 7 PROTEIN-LIKE HUMAN|HGNC=20528|UniProtKB=P60412 P60412 KRTAP10-11 PTHR23262:SF125 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-11 HUMAN|HGNC=19686|UniProtKB=Q99611 Q99611 SEPHS2 PTHR10256:SF1 SELENIDE, WATER DIKINASE SELENIDE, WATER DIKINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transferase#PC00220 HUMAN|HGNC=13091|UniProtKB=Q96RE9 Q96RE9 ZNF300 PTHR24377:SF926 IP01015P-RELATED ZINC FINGER PROTEIN 300 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=20887|UniProtKB=Q4AE62 Q4AE62 GTDC1 PTHR13615:SF3 GLYCOSYLTRANSFERASE-LIKE 1 GLYCOSYLTRANSFERASE-LIKE DOMAIN-CONTAINING PROTEIN 1 glycosyltransferase#PC00111 HUMAN|HGNC=11041|UniProtKB=Q9Y289 Q9Y289 SLC5A6 PTHR42985:SF2 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;sodium ion transport#GO:0006814;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812 secondary carrier transporter#PC00258 HUMAN|HGNC=18914|UniProtKB=A8MVA2 A8MVA2 KRTAP9-6 PTHR23262:SF190 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 9-6 HUMAN|HGNC=14184|UniProtKB=Q9H9P5 Q9H9P5 UNKL PTHR14493:SF37 UNKEMPT FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE UNKL-RELATED HUMAN|HGNC=20500|UniProtKB=Q9H7T0 Q9H7T0 CATSPERB PTHR14705:SF0 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT BETA CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT BETA membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;voltage-gated calcium channel complex#GO:0005891;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=8469|UniProtKB=Q8NGG7 Q8NGG7 OR8A1 PTHR48018:SF5 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=21536|UniProtKB=A6NNA5 A6NNA5 DRGX PTHR24329:SF542 HOMEOBOX PROTEIN ARISTALESS DORSAL ROOT GANGLIA HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=23927|UniProtKB=O14713 O14713 ITGB1BP1 PTHR32055:SF1 INTEGRIN BETA-1-BINDING PROTEIN 1 INTEGRIN BETA-1-BINDING PROTEIN 1 HUMAN|HGNC=9076|UniProtKB=O60240 O60240 PLIN1 PTHR47138:SF1 PERILIPIN-1 PERILIPIN-1 HUMAN|HGNC=16900|UniProtKB=O75940 O75940 SMNDC1 PTHR13681:SF26 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=24466|UniProtKB=O15061 O15061 SYNM PTHR47136:SF1 SYNEMIN SYNEMIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;structural molecule activity#GO:0005198;binding#GO:0005488 multicellular organismal process#GO:0032501;skeletal muscle contraction#GO:0003009;striated muscle contraction#GO:0006941;muscle system process#GO:0003012;muscle contraction#GO:0006936;system process#GO:0003008 supramolecular complex#GO:0099080;intermediate filament#GO:0005882;intermediate filament cytoskeleton#GO:0045111;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;sarcolemma#GO:0042383;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cytoskeleton#GO:0005856;myofibril#GO:0030016;plasma membrane#GO:0005886 HUMAN|HGNC=8591|UniProtKB=Q13177 Q13177 PAK2 PTHR48015:SF22 SERINE/THREONINE-PROTEIN KINASE TAO SERINE/THREONINE-PROTEIN KINASE PAK 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;axonogenesis#GO:0007409;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;regulation of neuron differentiation#GO:0045664;primary metabolic process#GO:0044238;regulation of neuron projection development#GO:0010975;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of axonogenesis#GO:0050770;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of cell morphogenesis involved in differentiation#GO:0010769;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell development#GO:0060284;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 T cell activation#P00053>PAK#P01319;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517;Ras Pathway#P04393>PAK#P04553;Angiogenesis#P00005>PAK#P00249 HUMAN|HGNC=16704|UniProtKB=Q9P2U7 Q9P2U7 SLC17A7 PTHR11662:SF29 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;L-glutamate transmembrane transporter activity#GO:0005313;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;ion transport#GO:0006811;transport#GO:0006810;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;regulation of synapse structure or activity#GO:0050803;synaptic transmission, glutamatergic#GO:0035249;signaling#GO:0023052;cell-cell signaling#GO:0007267;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;transport vesicle membrane#GO:0030658;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 Metabotropic glutamate receptor group III pathway#P00039>Vglut#P01038 HUMAN|HGNC=25875|UniProtKB=Q9H7X0 Q9H7X0 NAA60 PTHR14744:SF15 N-ALPHA-ACETYLTRANSFERASE 60 N-ALPHA-ACETYLTRANSFERASE 60 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;N-acyltransferase activity#GO:0016410 histone H3 acetylation#GO:0043966;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;peptidyl-amino acid modification#GO:0018193;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;histone H4 acetylation#GO:0043967;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;peptidyl-lysine modification#GO:0018205;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;histone modification#GO:0016570;protein maturation#GO:0051604;cellular component organization#GO:0016043;protein acylation#GO:0043543;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;organelle organization#GO:0006996;N-terminal protein amino acid acetylation#GO:0006474;chromatin organization#GO:0006325;protein acetylation#GO:0006473;internal protein amino acid acetylation#GO:0006475 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 acetyltransferase#PC00038 HUMAN|HGNC=28991|UniProtKB=Q92622 Q92622 RUBCN PTHR45971:SF3 PHOX (PX) DOMAIN-CONTAINING PROTEIN RUN DOMAIN BECLIN-1-INTERACTING AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;negative regulation of kinase activity#GO:0033673;membrane organization#GO:0061024;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;negative regulation of cellular component organization#GO:0051129;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;regulation of endocytosis#GO:0030100;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;glycerophospholipid metabolic process#GO:0006650;negative regulation of transport#GO:0051051;regulation of macroautophagy#GO:0016241;negative regulation of autophagy#GO:0010507;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organophosphate metabolic process#GO:0019637;regulation of lipid metabolic process#GO:0019216;regulation of autophagosome maturation#GO:1901096;autophagy#GO:0006914;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;phosphatidylinositol phosphorylation#GO:0046854;regulation of cellular metabolic process#GO:0031323;lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;transport#GO:0006810;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;glycerolipid metabolic process#GO:0046486;regulation of transport#GO:0051049;catabolic process#GO:0009056;vesicle organization#GO:0016050;phosphorylation#GO:0016310;autophagosome maturation#GO:0097352;negative regulation of transferase activity#GO:0051348;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of autophagy#GO:0010506;negative regulation of phosphorus metabolic process#GO:0010563;negative regulation of cellular catabolic process#GO:0031330;phosphatidylinositol metabolic process#GO:0046488;regulation of cellular catabolic process#GO:0031329;negative regulation of macroautophagy#GO:0016242;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;negative regulation of phosphorylation#GO:0042326;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;cellular lipid metabolic process#GO:0044255;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=4280|UniProtKB=P36383 P36383 GJC1 PTHR11984:SF6 CONNEXIN GAP JUNCTION GAMMA-1 PROTEIN gap junction#PC00105 HUMAN|HGNC=25583|UniProtKB=Q5T2S8 Q5T2S8 ARMC4 PTHR46241:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 4 ARMC4 ARMADILLO REPEAT-CONTAINING PROTEIN 4 HUMAN|HGNC=20422|UniProtKB=P0DPB6 P0DPB6 POLR1D PTHR13946:SF28 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;RNA polymerase I complex#GO:0005736 DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 HUMAN|HGNC=40037|UniProtKB=Q68DL7 Q68DL7 C18orf63 PTHR28495:SF1 HYPOTHETICAL PROTEIN LOC100359752 DUF4708 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=4679|UniProtKB=Q9UMX6 Q9UMX6 GUCA1B PTHR23055:SF11 CALCIUM BINDING PROTEINS GUANYLYL CYCLASE-ACTIVATING PROTEIN 2 HUMAN|HGNC=20105|UniProtKB=Q9UPI3 Q9UPI3 FLVCR2 PTHR10924:SF3 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED FELINE LEUKEMIA VIRUS SUBGROUP C RECEPTOR-RELATED PROTEIN 2 tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 localization#GO:0051179;organic substance transport#GO:0071702;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;cation transport#GO:0006812 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=33842|UniProtKB=Q4LEZ3 Q4LEZ3 AARD PTHR32289:SF2 PROTEIN FAM167A ALANINE AND ARGININE-RICH DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=26098|UniProtKB=Q96EN9 Q96EN9 REX1BD PTHR28309:SF1 REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=28264|UniProtKB=Q86SE9 Q86SE9 PCGF5 PTHR45893:SF1 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 5 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone ubiquitination#GO:0016574;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;histone H2A ubiquitination#GO:0033522;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 HUMAN|HGNC=21184|UniProtKB=Q4ZHG4 Q4ZHG4 FNDC1 PTHR23197:SF8 TARSH-RELATED FIBRONECTIN DOMAIN-CONTAINING FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=16361|UniProtKB=Q9P202 Q9P202 WHRN PTHR23116:SF37 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED WHIRLIN 9+0 non-motile cilium#GO:0097731;supramolecular complex#GO:0099080;non-motile cilium#GO:0097730;cluster of actin-based cell projections#GO:0098862;actin-based cell projection#GO:0098858;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;stereocilium#GO:0032420;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;stereocilium bundle#GO:0032421;actin cytoskeleton#GO:0015629;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=30252|UniProtKB=Q93015 Q93015 NAA80 PTHR13538:SF4 N-ACETYLTRANSFERASE 6 N-ALPHA-ACETYLTRANSFERASE 80 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;N-acyltransferase activity#GO:0016410;N-acetyltransferase activity#GO:0008080;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;acetyltransferase activity#GO:0016407;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein acylation#GO:0043543;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transferase#PC00220 HUMAN|HGNC=29179|UniProtKB=Q96AY4 Q96AY4 TTC28 PTHR10098:SF106 RAPSYN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 28 scaffold/adaptor protein#PC00226 HUMAN|HGNC=10870|UniProtKB=Q92186 Q92186 ST8SIA2 PTHR11987:SF30 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8B transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=11052|UniProtKB=P31641 P31641 SLC6A6 PTHR11616:SF141 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT TAURINE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;neurotransmitter binding#GO:0042165;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;monocarboxylic acid transmembrane transporter activity#GO:0008028;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=19146|UniProtKB=Q3KNT7 Q3KNT7 NSUN5P1 PTHR22807:SF67 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING NOL1/NOP2/SUN DOMAIN FAMILY MEMBER 5B-RELATED cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17735|UniProtKB=Q5T3F8 Q5T3F8 TMEM63B PTHR13018:SF38 PROBABLE MEMBRANE PROTEIN DUF221-RELATED CSC1-LIKE PROTEIN 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=930|UniProtKB=Q9UBV7 Q9UBV7 B4GALT7 PTHR19300:SF30 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 7 glycosyltransferase#PC00111 Wnt signaling pathway#P00057>Calcineurin#P01446 HUMAN|HGNC=9211|UniProtKB=Q16633 Q16633 POU2AF1 PTHR15363:SF3 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 HUMAN|HGNC=14824|UniProtKB=Q8NGG4 Q8NGG4 OR8H1 PTHR48018:SF181 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8H1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=31109|UniProtKB=P0C2S0 P0C2S0 CTXN2 PTHR16736:SF2 CORTEXIN-1-RELATED CORTEXIN-2 HUMAN|HGNC=8179|UniProtKB=Q9P1Q5 Q9P1Q5 OR1A1 PTHR48001:SF50 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1A1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=23163|UniProtKB=Q8N2Z9 Q8N2Z9 CENPS PTHR22980:SF4 CORTISTATIN CENTROMERE PROTEIN S chromatin binding#GO:0003682;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;meiotic chromosome separation#GO:0051307;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;cellular nitrogen compound biosynthetic process#GO:0044271;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;replication fork processing#GO:0031297;cell cycle phase#GO:0022403;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;cellular macromolecule biosynthetic process#GO:0034645;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;DNA biosynthetic process#GO:0071897;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;biological phase#GO:0044848;aromatic compound biosynthetic process#GO:0019438;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;Fanconi anaemia nuclear complex#GO:0043240;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 neuropeptide#PC00162 HUMAN|HGNC=9318|UniProtKB=Q96LZ3 Q96LZ3 PPP3R2 PTHR45942:SF2 PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1 CALCINEURIN SUBUNIT B TYPE 2 Wnt signaling pathway#P00057>Calcineurin#P01446 HUMAN|HGNC=14214|UniProtKB=Q96RK0 Q96RK0 CIC PTHR13059:SF13 HMG-BOX TRANSCRIPTION FACTOR BBX PROTEIN CAPICUA HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=26308|UniProtKB=Q6ZTQ4 Q6ZTQ4 CDHR3 PTHR24027:SF425 CADHERIN-23 CADHERIN-23-RELATED cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=28309|UniProtKB=Q6PL45 Q6PL45 BRICD5 PTHR16483:SF0 GASTROKINE 1 BRICHOS DOMAIN-CONTAINING PROTEIN 5 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell population proliferation#GO:0008283;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=18501|UniProtKB=Q8TD47 Q8TD47 RPS4Y2 PTHR11581:SF7 30S/40S RIBOSOMAL PROTEIN S4 40S RIBOSOMAL PROTEIN S4, Y ISOFORM 2 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=4444|UniProtKB=P14770 P14770 GP9 PTHR22650:SF6 GLYCOPROTEIN IB BETA PLATELET GLYCOPROTEIN IX Blood coagulation#P00011>GP IX#P00455 HUMAN|HGNC=31972|UniProtKB=A7E2F4 A7E2F4 GOLGA8A PTHR10881:SF63 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8A-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=17273|UniProtKB=Q9NS87 Q9NS87 KIF15 PTHR24115:SF576 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF15 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=26928|UniProtKB=Q9UKY7 Q9UKY7 CDV3 PTHR16284:SF13 PROTEIN CDV3 HOMOLOG PROTEIN CDV3 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=4934|UniProtKB=P28067 P28067 HLA-DMA PTHR19944:SF50 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DM ALPHA CHAIN major histocompatibility complex protein#PC00149 T cell activation#P00053>MHC-antigen#P01316 HUMAN|HGNC=19881|UniProtKB=Q9BXX0 Q9BXX0 EMILIN2 PTHR15427:SF5 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-2 HUMAN|HGNC=10783|UniProtKB=Q01130 Q01130 SRSF2 PTHR23147:SF145 SERINE/ARGININE RICH SPLICING FACTOR SERINE/ARGININE-RICH SPLICING FACTOR 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=18235|UniProtKB=Q9H201 Q9H201 EPN3 PTHR12276:SF16 EPSIN/ENT-RELATED EPSIN-3 protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 HUMAN|HGNC=10481|UniProtKB=P34925 P34925 RYK PTHR24416:SF349 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE RYK signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=953|UniProtKB=Q9BZE3 Q9BZE3 BARHL1 PTHR24330:SF8 HOMEOBOX PROTEIN BARH-LIKE BARH-LIKE 1 HOMEOBOX PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=13804|UniProtKB=Q96NK8 Q96NK8 NEUROD6 PTHR19290:SF9 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=6802|UniProtKB=P43358 P43358 MAGEA4 PTHR11736:SF48 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 4-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=21385|UniProtKB=Q9UIY3 Q9UIY3 RWDD2A PTHR15955:SF3 RWD DOMAIN CONTAINING PROTEIN 2 RWD DOMAIN-CONTAINING PROTEIN 2A ubiquitin-protein ligase#PC00234 HUMAN|HGNC=8017|UniProtKB=Q92636 Q92636 NSMAF PTHR13743:SF123 BEIGE/BEACH-RELATED PROTEIN FAN HUMAN|HGNC=14323|UniProtKB=Q9NZQ8 Q9NZQ8 TRPM5 PTHR13800:SF5 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 5 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;localization#GO:0051179;divalent metal ion transport#GO:0070838;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=16991|UniProtKB=Q07065 Q07065 CKAP4 PTHR45161:SF1 CYTOSKELETON-ASSOCIATED PROTEIN 4 CYTOSKELETON-ASSOCIATED PROTEIN 4 HUMAN|HGNC=2188|UniProtKB=Q99715 Q99715 COL12A1 PTHR24020:SF17 COLLAGEN ALPHA COLLAGEN ALPHA-1(XII) CHAIN ectoderm development#GO:0007398;cellular developmental process#GO:0048869;mesoderm formation#GO:0001707;multicellular organism development#GO:0007275;developmental process#GO:0032502;ectoderm formation#GO:0001705;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;mesoderm development#GO:0007498;cell differentiation#GO:0030154;embryo development#GO:0009790;endoderm formation#GO:0001706;anatomical structure morphogenesis#GO:0009653;formation of primary germ layer#GO:0001704;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;multicellular organismal process#GO:0032501;mesoderm morphogenesis#GO:0048332;embryonic morphogenesis#GO:0048598;gastrulation#GO:0007369;endoderm development#GO:0007492 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=11291|UniProtKB=P11831 P11831 SRF PTHR48019:SF134 SERUM RESPONSE FACTOR HOMOLOG SERUM RESPONSE FACTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 CCKR signaling map#P06959>SRF#P07181;p38 MAPK pathway#P05918>SRF#P06025;PDGF signaling pathway#P00047>c-fos#P01145;Ras Pathway#P04393>SRF#P04561;Gonadotropin-releasing hormone receptor pathway#P06664>SRF#P06811;Interleukin signaling pathway#P00036>SRF#P00987;PDGF signaling pathway#P00047>SRF#P01165 HUMAN|HGNC=12993|UniProtKB=P98182 P98182 ZNF200 PTHR47772:SF1 ZINC FINGER PROTEIN 200 ZINC FINGER PROTEIN 200 HUMAN|HGNC=29420|UniProtKB=Q96DX4 Q96DX4 RSPRY1 PTHR13363:SF6 RING FINGER AND SRY DOMAIN-CONTAINING RING FINGER AND SPRY DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=49571|UniProtKB=B4DH59 B4DH59 NBPF26 PTHR14199:SF35 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 10-RELATED HUMAN|HGNC=18152|UniProtKB=Q9NP84 Q9NP84 TNFRSF12A PTHR32037:SF2 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 12A TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 12A transmembrane signal receptor#PC00197 HUMAN|HGNC=16422|UniProtKB=Q9BWT7 Q9BWT7 CARD10 PTHR14559:SF12 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 10 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=3340|UniProtKB=Q04741 Q04741 EMX1 PTHR24339:SF26 HOMEOBOX PROTEIN EMX-RELATED HOMEOBOX PROTEIN EMX1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=414|UniProtKB=P04075 P04075 ALDOA PTHR11627:SF1 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE A lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;fructose-bisphosphate aldolase activity#GO:0004332 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;purine ribonucleoside diphosphate metabolic process#GO:0009179;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aldolase#PC00044 Glycolysis#P00024>Aldolase#P00679;Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959 HUMAN|HGNC=16509|UniProtKB=Q9Y2D8 Q9Y2D8 SSX2IP PTHR46507:SF1 AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN HUMAN|HGNC=15026|UniProtKB=Q8NHC7 Q8NHC7 OR14C36 PTHR26452:SF180 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 14C36 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=11753|UniProtKB=P19484 P19484 TFEB PTHR45776:SF5 MIP04163P TRANSCRIPTION FACTOR EB cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16484|UniProtKB=Q9HAS3 Q9HAS3 SLC28A3 PTHR10590:SF4 SODIUM/NUCLEOSIDE COTRANSPORTER SOLUTE CARRIER FAMILY 28 MEMBER 3 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;nucleoside transmembrane transporter activity#GO:0005337;transmembrane transporter activity#GO:0022857;symporter activity#GO:0015293;nucleobase-containing compound transmembrane transporter activity#GO:0015932;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=29658|UniProtKB=Q9BRJ9 Q9BRJ9 MESP1 PTHR20937:SF6 IP14615P MESODERM POSTERIOR PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;ectoderm formation#GO:0001705;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;mesoderm morphogenesis#GO:0048332;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;ectoderm development#GO:0007398;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;epithelium development#GO:0060429;mesoderm formation#GO:0001707;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;endoderm formation#GO:0001706;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;mesoderm development#GO:0007498;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=23214|UniProtKB=Q9UPT5 Q9UPT5 EXOC7 PTHR12542:SF41 EXOCYST COMPLEX PROTEIN EXO70 EXOCYST COMPLEX COMPONENT 7 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 membrane traffic protein#PC00150 HUMAN|HGNC=18866|UniProtKB=Q6UVM3 Q6UVM3 KCNT2 PTHR10027:SF9 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY T MEMBER 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;ion channel activity#GO:0005216;potassium ion transmembrane transporter activity#GO:0015079;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 ion channel#PC00133 HUMAN|HGNC=12216|UniProtKB=A0A539 A0A539 TRBV4-2 PTHR23268:SF40 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 4-2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=10659|UniProtKB=P34741 P34741 SDC2 PTHR10915:SF6 SYNDECAN SYNDECAN-2 localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 transmembrane signal receptor#PC00197 HUMAN|HGNC=37163|UniProtKB=P0CJ73 P0CJ73 MTRNR2L6 PTHR33895:SF18 HUMANIN-LIKE 4 HUMANIN-LIKE 1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=42673|UniProtKB=A6NFA0 A6NFA0 FAM205C PTHR21859:SF15 ACROSOME-SPECIFIC PROTEIN PROTEIN FAM205A-RELATED HUMAN|HGNC=11985|UniProtKB=O94826 O94826 TOMM70 PTHR46208:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 primary active transporter#PC00068 HUMAN|HGNC=24818|UniProtKB=Q9P0K8 Q9P0K8 FOXJ2 PTHR46078:SF1 FORKHEAD BOX PROTEIN J2 FAMILY MEMBER FORKHEAD BOX PROTEIN J2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=17286|UniProtKB=Q9Y3B2 Q9Y3B2 EXOSC1 PTHR12686:SF8 3'-5' EXORIBONUCLEASE CSL4-RELATED EXOSOME COMPLEX COMPONENT CSL4 exoribonuclease#PC00099 HUMAN|HGNC=5381|UniProtKB=P14735 P14735 IDE PTHR43690:SF31 NARDILYSIN INSULIN-DEGRADING ENZYME macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 metalloprotease#PC00153 HUMAN|HGNC=3802|UniProtKB=Q16676 Q16676 FOXD1 PTHR11829:SF348 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=12568|UniProtKB=Q8IZJ1 Q8IZJ1 UNC5B PTHR12582:SF6 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5B neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 HUMAN|HGNC=9137|UniProtKB=Q06265 Q06265 EXOSC9 PTHR11097:SF14 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP45 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;modification-dependent macromolecule catabolic process#GO:0043632;mRNA 3'-end processing#GO:0031124;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;mRNA catabolic process#GO:0006402;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;snRNA processing#GO:0016180;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;maturation of 5.8S rRNA#GO:0000460;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;cleavage involved in rRNA processing#GO:0000469;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;snRNA metabolic process#GO:0016073;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA polyadenylation#GO:0006378;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;nucleic acid phosphodiester bond hydrolysis#GO:0090305;rRNA metabolic process#GO:0016072;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;exosome (RNase complex)#GO:0000178;intracellular organelle#GO:0043229 exoribonuclease#PC00099 HUMAN|HGNC=47|UniProtKB=Q9NP58 Q9NP58 ABCB6 PTHR24221:SF586 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6, MITOCHONDRIAL pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;tetrapyrrole binding#GO:0046906;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATPase activity#GO:0016887;heme binding#GO:0020037 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;cation transport#GO:0006812;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular iron ion homeostasis#GO:0006879;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;organic substance transport#GO:0071702;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;iron ion homeostasis#GO:0055072;biological regulation#GO:0065007;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;metal ion homeostasis#GO:0055065 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=5755|UniProtKB=P0DSN7 P0DSN7 IGKV1D-37 PTHR23267:SF468 IMMUNOGLOBULIN LIGHT CHAIN NON-FUNCTIONAL IMMUNOGLOBULINN KAPPA VARIABLE 1-37-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=12141|UniProtKB=A0A0B4J280 A0A0B4J280 TRAV40 PTHR23267:SF119 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 40 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=14919|UniProtKB=Q9NYV9 Q9NYV9 TAS2R13 PTHR11394:SF28 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 13 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=541|UniProtKB=P12429 P12429 ANXA3 PTHR10502:SF25 ANNEXIN ANNEXIN A3 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calcium-binding protein#PC00060 HUMAN|HGNC=2553|UniProtKB=Q13618 Q13618 CUL3 PTHR11932:SF168 CULLIN CULLIN-3 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=20861|UniProtKB=Q9ULF5 Q9ULF5 SLC39A10 PTHR12191:SF14 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP10 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;inorganic ion homeostasis#GO:0098771;activation of immune response#GO:0002253;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;inorganic cation transmembrane transport#GO:0098662;B cell receptor signaling pathway#GO:0050853;inorganic ion transmembrane transport#GO:0098660;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;immune response-activating signal transduction#GO:0002757;divalent inorganic cation transport#GO:0072511;transition metal ion transport#GO:0000041;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cellular cation homeostasis#GO:0030003;immune response-regulating cell surface receptor signaling pathway#GO:0002768;transition metal ion homeostasis#GO:0055076;regulation of immune response#GO:0050776;cell communication#GO:0007154;cation homeostasis#GO:0055080;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;immune response-activating cell surface receptor signaling pathway#GO:0002429;metal ion homeostasis#GO:0055065;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;regulation of signaling#GO:0023051;transport#GO:0006810;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;positive regulation of response to stimulus#GO:0048584;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;regulation of immune system process#GO:0002682;signaling#GO:0023052;cellular transition metal ion homeostasis#GO:0046916;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;immune response#GO:0006955;ion transport#GO:0006811;homeostatic process#GO:0042592;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;response to stimulus#GO:0050896;immune system process#GO:0002376;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular zinc ion homeostasis#GO:0006882 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=28209|UniProtKB=Q96LK0 Q96LK0 CEP19 PTHR31539:SF1 CENTROSOMAL PROTEIN OF 19K CEP19 CENTROSOMAL PROTEIN OF 19 KDA vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;microtubule anchoring#GO:0034453;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 spindle pole#GO:0000922;microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;spindle#GO:0005819;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=14002|UniProtKB=O14519 O14519 CDK2AP1 PTHR22607:SF2 DELETED IN ORAL CANCER 1/CDK2-ASSOCIATED PROTEIN 1 CYCLIN-DEPENDENT KINASE 2-ASSOCIATED PROTEIN 1 kinase inhibitor#PC00139 HUMAN|HGNC=165|UniProtKB=Q08043 Q08043 ACTN3 PTHR11915:SF432 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ-3 Integrin signalling pathway#P00034>alpha actinin#P00928 HUMAN|HGNC=12020|UniProtKB=O60507 O60507 TPST1 PTHR12788:SF4 PROTEIN-TYROSINE SULFOTRANSFERASE 2 PROTEIN-TYROSINE SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;peptidyl-tyrosine modification#GO:0018212;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transferase#PC00220 CCKR signaling map#P06959>Protein tyrosine sulfotransferase#P07148 HUMAN|HGNC=30380|UniProtKB=Q9NV70 Q9NV70 EXOC1 PTHR16092:SF28 SEC3/SYNTAXIN-RELATED EXOCYST COMPLEX COMPONENT 1-RELATED phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;phospholipid binding#GO:0005543;GTP-Rho binding#GO:0017049;phosphatidylinositol phosphate binding#GO:1901981;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;phosphatidylinositol bisphosphate binding#GO:1902936;Ras GTPase binding#GO:0017016;protein binding#GO:0005515;lipid binding#GO:0008289;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167 vesicle fusion#GO:0006906;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;exocytic process#GO:0140029;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;vesicle organization#GO:0016050;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 SNARE protein#PC00034 HUMAN|HGNC=13124|UniProtKB=Q15929 Q15929 ZNF56 PTHR24381:SF363 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 56-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15255|UniProtKB=Q8NGI8 Q8NGI8 OR5AN1 PTHR26452:SF262 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AN1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=29620|UniProtKB=Q8TBF4 Q8TBF4 ZCRB1 PTHR46259:SF2 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U12-type spliceosomal complex#GO:0005689 HUMAN|HGNC=28417|UniProtKB=Q9BTE6 Q9BTE6 AARSD1 PTHR43462:SF1 ALANYL-TRNA EDITING PROTEIN ALANYL-TRNA EDITING PROTEIN AARSD1 catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 biological regulation#GO:0065007;regulation of biological quality#GO:0065008 RNA metabolism protein#PC00031 HUMAN|HGNC=10832|UniProtKB=Q99963 Q99963 SH3GL3 PTHR14167:SF45 SH3 DOMAIN-CONTAINING ENDOPHILIN-A3 Huntington disease#P00029>SH3GL3#P00813 HUMAN|HGNC=19097|UniProtKB=Q93062 Q93062 RBPMS PTHR10501:SF25 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B RNA-BINDING PROTEIN WITH MULTIPLE SPLICING nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA splicing factor#PC00148 HUMAN|HGNC=15291|UniProtKB=Q96RB7 Q96RB7 OR5M11 PTHR48018:SF106 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M11 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=30402|UniProtKB=Q9BQF6 Q9BQF6 SENP7 PTHR46896:SF2 SENTRIN-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 7 cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein-specific protease activity#GO:0019783;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|Gene=KV113_HUMAN|UniProtKB=P0DP09 P0DP09 IGKV1-13 PTHR23267:SF411 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-13-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=29013|UniProtKB=Q2KHT3 Q2KHT3 CLEC16A PTHR21481:SF0 UNCHARACTERIZED PROTEIN CLEC16A GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 endosomal transport#GO:0016197;cellular localization#GO:0051641;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;transport#GO:0006810;regulation of cellular component organization#GO:0051128;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;cellular component disassembly#GO:0022411;establishment of localization#GO:0051234;catabolic process#GO:0009056;autophagosome maturation#GO:0097352;protein-containing complex subunit organization#GO:0043933;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;protein-containing complex disassembly#GO:0032984;vacuolar transport#GO:0007034;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;regulation of macroautophagy#GO:0016241;cellular component organization#GO:0016043;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;regulation of autophagosome maturation#GO:1901096;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;intrinsic component of membrane#GO:0031224;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=24336|UniProtKB=Q8IYJ1 Q8IYJ1 CPNE9 PTHR10857:SF112 COPINE COPINE-9 calcium-dependent phospholipid binding#GO:0005544;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;binding#GO:0005488 response to metal ion#GO:0010038;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=6005|UniProtKB=Q9HBE4 Q9HBE4 IL21 PTHR14356:SF2 INTERLEUKIN-15-RELATED INTERLEUKIN-21 interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Interleukin#P00970 HUMAN|HGNC=26472|UniProtKB=Q96MW1 Q96MW1 CCDC43 PTHR31684:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 HUMAN|HGNC=12228|UniProtKB=P0DPF7 P0DPF7 TRBV6-3 PTHR23268:SF19 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 6-2-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=15260|UniProtKB=Q8NGP9 Q8NGP9 OR5AR1 PTHR26452:SF315 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AR1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=20864|UniProtKB=Q7Z769 Q7Z769 SLC35E3 PTHR11132:SF250 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E3 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide-sugar transmembrane transporter activity#GO:0005338;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=26431|UniProtKB=Q6BAA4 Q6BAA4 FCRLB PTHR11481:SF94 IMMUNOGLOBULIN FC RECEPTOR FC RECEPTOR-LIKE B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;regulation of immune system process#GO:0002682;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=20604|UniProtKB=Q9Y2L1 Q9Y2L1 DIS3 PTHR23355:SF35 RIBONUCLEASE EXOSOME COMPLEX EXONUCLEASE RRP44 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;exosome (RNase complex)#GO:0000178;intracellular organelle#GO:0043229 exoribonuclease#PC00099 HUMAN|HGNC=12868|UniProtKB=O95159 O95159 ZFPL1 PTHR12981:SF0 ZINC FINGER PROTEIN-LIKE 1 ZINC FINGER PROTEIN-LIKE 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=9998|UniProtKB=P41220 P41220 RGS2 PTHR10845:SF43 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 2 GTPase-activating protein#PC00257 CCKR signaling map#P06959>RGS2#P07040;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=13796|UniProtKB=Q8IYD9 Q8IYD9 LAS2 PTHR35079:SF1 LUNG ADENOMA SUSCEPTIBILITY PROTEIN 2 LUNG ADENOMA SUSCEPTIBILITY PROTEIN 2 HUMAN|HGNC=7835|UniProtKB=O95096 O95096 NKX2-2 PTHR24340:SF24 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=11627|UniProtKB=Q12870 Q12870 TCF15 PTHR23349:SF4 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 15 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=13265|UniProtKB=Q9HBI6 Q9HBI6 CYP4F11 PTHR24291:SF112 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F11 oxygenase#PC00177 HUMAN|HGNC=6272|UniProtKB=O00180 O00180 KCNK1 PTHR11003:SF59 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=9609|UniProtKB=P49190 P49190 PTH2R PTHR45620:SF7 PDF RECEPTOR-LIKE PROTEIN-RELATED PARATHYROID HORMONE 2 RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=33|UniProtKB=Q99758 Q99758 ABCA3 PTHR19229:SF98 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 3 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=6027|UniProtKB=P25025 P25025 CXCR2 PTHR10489:SF689 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 2 cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;neutrophil migration#GO:1990266;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;granulocyte chemotaxis#GO:0071621;response to chemical#GO:0042221;myeloid leukocyte migration#GO:0097529;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;leukocyte chemotaxis#GO:0030595;locomotion#GO:0040011;chemotaxis#GO:0006935;taxis#GO:0042330 Interleukin signaling pathway#P00036>Receptor subunit beta#P00974;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=10807|UniProtKB=Q92629 Q92629 SGCD PTHR12939:SF6 SARCOGLYCAN DELTA-SARCOGLYCAN blood circulation#GO:0008015;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;heart contraction#GO:0060047;multicellular organism development#GO:0007275;cardiac muscle tissue development#GO:0048738;system process#GO:0003008;developmental process#GO:0032502;circulatory system process#GO:0003013;tissue development#GO:0009888;muscle tissue development#GO:0060537;system development#GO:0048731;striated muscle tissue development#GO:0014706;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;heart process#GO:0003015 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;sarcolemma#GO:0042383 cytoskeletal protein#PC00085 HUMAN|HGNC=18212|UniProtKB=Q9UM19 Q9UM19 HPCAL4 PTHR23055:SF84 CALCIUM BINDING PROTEINS HIPPOCALCIN-LIKE PROTEIN 4 HUMAN|HGNC=10363|UniProtKB=P18124 P18124 RPL7 PTHR11524:SF12 60S RIBOSOMAL PROTEIN L7 60S RIBOSOMAL PROTEIN L7 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=9291|UniProtKB=Q16821 Q16821 PPP1R3A PTHR12307:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3A phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase 1 binding#GO:0008157;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 monosaccharide metabolic process#GO:0005996;glucan metabolic process#GO:0044042;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;energy derivation by oxidation of organic compounds#GO:0015980;regulation of biological process#GO:0050789;cellular glucan metabolic process#GO:0006073;glucan biosynthetic process#GO:0009250;regulation of biosynthetic process#GO:0009889;oxidation-reduction process#GO:0055114;regulation of macromolecule biosynthetic process#GO:0010556;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;glycogen biosynthetic process#GO:0005978;regulation of glucose metabolic process#GO:0010906;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;polysaccharide metabolic process#GO:0005976;regulation of cellular biosynthetic process#GO:0031326;cellular carbohydrate metabolic process#GO:0044262;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;hexose metabolic process#GO:0019318;energy reserve metabolic process#GO:0006112;cellular polysaccharide biosynthetic process#GO:0033692;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular polysaccharide metabolic process#GO:0044264;small molecule metabolic process#GO:0044281 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 phosphatase modulator#PC00184 HUMAN|HGNC=15767|UniProtKB=Q96AC1 Q96AC1 FERMT2 PTHR16160:SF11 FERMITIN 2-RELATED FERMITIN FAMILY HOMOLOG 2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;biological adhesion#GO:0022610 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;anchoring junction#GO:0070161;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;intracellular#GO:0005622;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 HUMAN|HGNC=28370|UniProtKB=Q9BTN0 Q9BTN0 LRFN3 PTHR45842:SF5 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 3 cellular component biogenesis#GO:0044085;regulation of cell-cell adhesion#GO:0022407;developmental process#GO:0032502;biological adhesion#GO:0022610;synaptic membrane adhesion#GO:0099560;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;cell junction assembly#GO:0034329;regulation of cell adhesion#GO:0030155;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell junction assembly#GO:1901888;regulation of synapse structure or activity#GO:0050803 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;presynaptic membrane#GO:0042734;asymmetric synapse#GO:0032279;cell surface#GO:0009986;intrinsic component of membrane#GO:0031224;intrinsic component of synaptic membrane#GO:0099240;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;intrinsic component of postsynaptic specialization membrane#GO:0098948;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;presynapse#GO:0098793;intrinsic component of postsynaptic membrane#GO:0098936;postsynaptic specialization#GO:0099572;integral component of synaptic membrane#GO:0099699;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;membrane#GO:0016020;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;integral component of postsynaptic specialization membrane#GO:0099060;integral component of postsynaptic membrane#GO:0099055;presynaptic active zone#GO:0048786;integral component of postsynaptic density membrane#GO:0099061;integral component of plasma membrane#GO:0005887;plasma membrane#GO:0005886 HUMAN|HGNC=18855|UniProtKB=Q68CJ9 Q68CJ9 CREB3L3 PTHR45996:SF1 AGAP001464-PB CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CPB#P00702 HUMAN|HGNC=29238|UniProtKB=Q9ULD9 Q9ULD9 ZNF608 PTHR21564:SF4 BRAKELESS PROTEIN ZINC FINGER PROTEIN 608 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28199|UniProtKB=Q9BRD0 Q9BRD0 BUD13 PTHR31809:SF0 BUD13 HOMOLOG BUD13 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=21100|UniProtKB=Q96PU8 Q96PU8 QKI PTHR11208:SF125 RNA-BINDING PROTEIN RELATED PROTEIN QUAKING nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA splicing factor#PC00148 HUMAN|HGNC=25071|UniProtKB=Q6IBW4 Q6IBW4 NCAPH2 PTHR14324:SF3 CONDENSIN-2 COMPLEX SUBUNIT H2 CONDENSIN-2 COMPLEX SUBUNIT H2 binding#GO:0005488;chromatin binding#GO:0003682 nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;chromosome organization involved in meiotic cell cycle#GO:0070192;DNA packaging#GO:0006323;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic cell cycle process#GO:1903046;reproductive process#GO:0022414;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4038|UniProtKB=Q9UP38 Q9UP38 FZD1 PTHR11309:SF81 FRIZZLED FRIZZLED-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Angiogenesis#P00005>FRP#P00237;Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 HUMAN|HGNC=26901|UniProtKB=Q3ZCN5 Q3ZCN5 OTOGL PTHR11339:SF225 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED OTOGELIN-LIKE PROTEIN extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=17830|UniProtKB=Q5VW38 Q5VW38 GPR107 PTHR21229:SF12 LUNG SEVEN TRANSMEMBRANE RECEPTOR PROTEIN GPR107 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=9299|UniProtKB=P67775 P67775 PPP2CA PTHR45619:SF42 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT ALPHA ISOFORM protein phosphatase#PC00195 p53 pathway#P00059>PP2A#P04630;Wnt signaling pathway#P00057>PP2A#P01438;p53 pathway feedback loops 2#P04398>PP2A-C#P04659;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 HUMAN|HGNC=12310|UniProtKB=Q15650 Q15650 TRIP4 PTHR12963:SF0 THYROID RECEPTOR INTERACTING PROTEIN RELATED ACTIVATING SIGNAL COINTEGRATOR 1 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=7142|UniProtKB=P49006 P49006 MARCKSL1 PTHR14353:SF8 MYRISTOYLATED ALANINE-RICH C-KINASE SUBSTRATE MARCKS MARCKS-RELATED PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;central nervous system development#GO:0007417;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 HUMAN|HGNC=1232|UniProtKB=Q9GZT9 Q9GZT9 EGLN1 PTHR12907:SF4 EGL NINE HOMOLOG-RELATED EGL NINE HOMOLOG 1 cation binding#GO:0043169;ferrous iron binding#GO:0008198;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;dioxygenase activity#GO:0051213;metal ion binding#GO:0046872;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;response to hypoxia#GO:0001666;cellular response to chemical stimulus#GO:0070887;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;response to decreased oxygen levels#GO:0036293;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular response to hypoxia#GO:0071456;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;response to abiotic stimulus#GO:0009628;cellular protein metabolic process#GO:0044267;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;response to oxygen levels#GO:0070482 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Hypoxia response via HIF activation#P00030>Prolyl Hydroxylase#P00821 HUMAN|HGNC=23718|UniProtKB=Q8TBZ5 Q8TBZ5 ZNF502 PTHR24384:SF126 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 502 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=15842|UniProtKB=Q96RT1 Q96RT1 ERBIN PTHR45752:SF47 LEUCINE-RICH REPEAT-CONTAINING ERBIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|HGNC=4528|UniProtKB=Q96P69 Q96P69 GPR78 PTHR24245:SF7 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 78 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 G-protein coupled receptor#PC00021 HUMAN|HGNC=11849|UniProtKB=O15455 O15455 TLR3 PTHR24373:SF293 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TOLL-LIKE RECEPTOR 3 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 Toll receptor signaling pathway#P00054>TLR3#P01340;Toll receptor signaling pathway#P00054>TLR#P01346 HUMAN|HGNC=1539|UniProtKB=Q13951 Q13951 CBFB PTHR10276:SF3 CORE-BINDING FACTOR, BETA SUBUNIT CORE-BINDING FACTOR SUBUNIT BETA sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;transcription coactivator activity#GO:0003713;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=26754|UniProtKB=A2RUC4 A2RUC4 TYW5 PTHR12461:SF80 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 5 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 HUMAN|HGNC=23708|UniProtKB=Q6ZR52 Q6ZR52 ZNF493 PTHR24376:SF120 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 493 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=2861|UniProtKB=P00374 P00374 DHFR PTHR48069:SF6 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;NADP binding#GO:0050661;oxidoreductase activity#GO:0016491 cellular aromatic compound metabolic process#GO:0006725;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;pteridine-containing compound metabolic process#GO:0042558;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;heterocycle biosynthetic process#GO:0018130;amide biosynthetic process#GO:0043604;folic acid-containing compound biosynthetic process#GO:0009396;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 reductase#PC00198 Formyltetrahydroformate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 HUMAN|HGNC=31124|UniProtKB=P58550 P58550 FXYD6P3 PTHR14132:SF15 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 6-RELATED cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of sodium ion transport#GO:0002028;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;sodium ion transport#GO:0006814;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;sodium ion transmembrane transport#GO:0035725 primary active transporter#PC00068 HUMAN|HGNC=20739|UniProtKB=Q8NFU5 Q8NFU5 IPMK PTHR12400:SF80 INOSITOL POLYPHOSPHATE KINASE INOSITOL POLYPHOSPHATE MULTIKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 HUMAN|HGNC=9984|UniProtKB=P48380 P48380 RFX3 PTHR12619:SF20 RFX TRANSCRIPTION FACTOR FAMILY TRANSCRIPTION FACTOR RFX3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=3638|UniProtKB=P10109 P10109 FDX1 PTHR23426:SF26 FERREDOXIN/ADRENODOXIN ADRENODOXIN, MITOCHONDRIAL oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FDX#P04607 HUMAN|HGNC=15108|UniProtKB=Q8NGT2 Q8NGT2 OR13J1 PTHR26453:SF38 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13J1 transmembrane signal receptor#PC00197 HUMAN|HGNC=13753|UniProtKB=Q9BXM9 Q9BXM9 FSD1L PTHR24099:SF8 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED FSD1-LIKE PROTEIN ubiquitin-protein ligase#PC00234 HUMAN|HGNC=16901|UniProtKB=Q15772 Q15772 SPEG PTHR47633:SF3 IMMUNOGLOBULIN STRIATED MUSCLE PREFERENTIALLY EXPRESSED PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 HUMAN|HGNC=11929|UniProtKB=Q9Y275 Q9Y275 TNFSF13B PTHR15151:SF2 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 HUMAN|HGNC=6596|UniProtKB=P15018 P15018 LIF PTHR10633:SF0 LEUKEMIA INHIBITORY FACTOR LEUKEMIA INHIBITORY FACTOR cytokine#PC00083 HUMAN|HGNC=2041|UniProtKB=P57739 P57739 CLDN2 PTHR12002:SF110 CLAUDIN CLAUDIN-2 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell junction assembly#GO:0034329;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=30256|UniProtKB=Q9Y3Y4 Q9Y3Y4 PYGO1 PTHR23194:SF3 PYGOPUS PYGOPUS HOMOLOG 1 Wnt signaling pathway#P00057>Pygo#P01464 HUMAN|HGNC=15516|UniProtKB=Q86Y38 Q86Y38 XYLT1 PTHR46025:SF2 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;UDP-xylosyltransferase activity#GO:0035252;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity, acting on a protein#GO:0140096;xylosyltransferase activity#GO:0042285 glycoprotein biosynthetic process#GO:0009101;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;chondroitin sulfate proteoglycan metabolic process#GO:0050654;carbohydrate derivative biosynthetic process#GO:1901137;heparan sulfate proteoglycan metabolic process#GO:0030201;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycoprotein metabolic process#GO:0009100 transferase#PC00220 HUMAN|HGNC=8208|UniProtKB=Q8NGS3 Q8NGS3 OR1J1 PTHR48001:SF148 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1J1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=11973|UniProtKB=Q9HBL0 Q9HBL0 TNS1 PTHR45734:SF3 TENSIN TENSIN-1 non-motor actin binding protein#PC00165 HUMAN|HGNC=11028|UniProtKB=P04920 P04920 SLC4A2 PTHR11453:SF14 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN 2 secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;anion:anion antiporter activity#GO:0015301;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=21370|UniProtKB=Q6DKI1 Q6DKI1 RPL7L1 PTHR11524:SF13 60S RIBOSOMAL PROTEIN L7 60S RIBOSOMAL PROTEIN L7-LIKE 1 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=25642|UniProtKB=Q5VWQ0 Q5VWQ0 RSBN1 PTHR13354:SF8 ROUND SPERMATID BASIC PROTEIN 1 LYSINE-SPECIFIC DEMETHYLASE 9 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=48335|UniProtKB=Q5H9J9 Q5H9J9 TCP11X2 PTHR12832:SF21 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11 X-LINKED PROTEIN 1-RELATED male gamete generation#GO:0048232;signal transduction#GO:0007165;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;spermatid differentiation#GO:0048515;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;spermatogenesis#GO:0007283;reproductive process#GO:0022414;regulation of multi-organism process#GO:0043900;intracellular signal transduction#GO:0035556;multi-organism reproductive process#GO:0044703;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609;sperm capacitation#GO:0048240;germ cell development#GO:0007281;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;gamete generation#GO:0007276;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;multicellular organism reproduction#GO:0032504;cell communication#GO:0007154;regulation of reproductive process#GO:2000241;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;response to stimulus#GO:0050896;reproduction#GO:0000003;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 supramolecular complex#GO:0099080;axoneme#GO:0005930;acrosomal vesicle#GO:0001669;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;cytoplasmic microtubule#GO:0005881;vacuole#GO:0005773;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;B axonemal microtubule#GO:0097650;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;intracellular vesicle#GO:0097708;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;cytoplasmic vesicle#GO:0031410;dynein complex#GO:0030286;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=13153|UniProtKB=Q15937 Q15937 ZNF79 PTHR24381:SF344 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 79 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20427|UniProtKB=Q9NS73 Q9NS73 MBIP PTHR23404:SF3 MOLYBDOPTERIN SYNTHASE RELATED MAP3K12-BINDING INHIBITORY PROTEIN 1 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=10437|UniProtKB=Q9UBS0 Q9UBS0 RPS6KB2 PTHR24351:SF171 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE BETA-2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 p53 pathway by glucose deprivation#P04397>S6K#P04636;PI3 kinase pathway#P00048>S6K#P01194;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 HUMAN|HGNC=33527|UniProtKB=F8WCM5 F8WCM5 INS-IGF2 PTHR11454:SF32 INSULIN/INSULIN GROWTH FACTOR INSULIN, ISOFORM 2 growth factor#PC00112 HUMAN|HGNC=31860|UniProtKB=Q6NSI3 Q6NSI3 FAM53A PTHR28567:SF2 FAMILY NOT NAMED PROTEIN FAM53A cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18061|UniProtKB=Q9BY08 Q9BY08 EBPL PTHR14207:SF4 STEROL ISOMERASE EMOPAMIL-BINDING PROTEIN-LIKE isomerase activity#GO:0016853;catalytic activity#GO:0003824 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;sterol biosynthetic process#GO:0016126;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 isomerase#PC00135 HUMAN|HGNC=29477|UniProtKB=O15243 O15243 LEPROT PTHR12050:SF3 LEPTIN RECEPTOR-RELATED LEPTIN RECEPTOR GENE-RELATED PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;late endosome to vacuole transport#GO:0045324;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;negative regulation of cell communication#GO:0010648;regulation of protein localization#GO:0032880;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;protein localization to cell surface#GO:0034394;regulation of cellular localization#GO:0060341;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;endosome transport via multivesicular body sorting pathway#GO:0032509;negative regulation of signal transduction#GO:0009968;intracellular transport#GO:0046907;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;response to peptide hormone#GO:0043434;cellular protein localization#GO:0034613;regulation of signaling#GO:0023051;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular response to nitrogen compound#GO:1901699;regulation of receptor signaling pathway via STAT#GO:1904892;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;response to peptide#GO:1901652;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;vacuolar transport#GO:0007034;cellular response to peptide#GO:1901653;multivesicular body sorting pathway#GO:0071985;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;receptor signaling pathway via STAT#GO:0097696;response to hormone#GO:0009725;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=15228|UniProtKB=Q8NGI0 Q8NGI0 OR52N2 PTHR26450:SF161 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N2 transmembrane signal receptor#PC00197 HUMAN|HGNC=11195|UniProtKB=P48431 P48431 SOX2 PTHR10270:SF231 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=27269|UniProtKB=Q6ZQW0 Q6ZQW0 IDO2 PTHR28657:SF4 INDOLEAMINE 2,3-DIOXYGENASE INDOLEAMINE 2,3-DIOXYGENASE 2 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;organophosphate biosynthetic process#GO:0090407;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;aromatic amino acid family metabolic process#GO:0009072;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;cellular amino acid metabolic process#GO:0006520;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxygenase#PC00177 HUMAN|HGNC=11240|UniProtKB=Q9NYA1 Q9NYA1 SPHK1 PTHR12358:SF47 SPHINGOSINE KINASE SPHINGOSINE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;kinase activity#GO:0016301;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;alcohol biosynthetic process#GO:0046165;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;negative regulation of programmed cell death#GO:0043069;cellular nitrogen compound biosynthetic process#GO:0044271;apoptotic process#GO:0006915;cell death#GO:0008219;phosphorylation#GO:0016310;negative regulation of cellular process#GO:0048523;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;response to organic substance#GO:0010033;organic hydroxy compound metabolic process#GO:1901615;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;negative regulation of apoptotic process#GO:0043066;primary metabolic process#GO:0044238;negative regulation of cell death#GO:0060548;response to stimulus#GO:0050896;membrane lipid metabolic process#GO:0006643;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 Angiogenesis#P00005>SPK#P00229;VEGF signaling pathway#P00056>SPK#P01404 HUMAN|HGNC=1529|UniProtKB=P56539 P56539 CAV3 PTHR10844:SF16 CAVEOLIN CAVEOLIN-3 ion channel binding#GO:0044325;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;regulation of biological quality#GO:0065008;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987 plasma membrane raft#GO:0044853;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;membrane raft#GO:0045121;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;membrane region#GO:0098589;membrane microdomain#GO:0098857;whole membrane#GO:0098805;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=2360|UniProtKB=P50238 P50238 CRIP1 PTHR46074:SF3 CYSTEINE-RICH PROTEIN CRIP FAMILY MEMBER CYSTEINE-RICH PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;zinc ion binding#GO:0008270;binding#GO:0005488;transition metal ion binding#GO:0046914 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;cellular response to stress#GO:0033554;signaling#GO:0023052;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=12613|UniProtKB=Q9Y4E8 Q9Y4E8 USP15 PTHR21646:SF28 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 cysteine protease#PC00081 HUMAN|HGNC=7423|UniProtKB=P56278 P56278 MTCP1 PTHR14060:SF8 PROTEIN P13 MTCP-1 PROTEIN P13 MTCP-1 HUMAN|HGNC=9904|UniProtKB=Q9Y580 Q9Y580 RBM7 PTHR13798:SF4 RNA BINDING MOTIF RBM PROTEIN -RELATED RNA-BINDING PROTEIN 7 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=557|UniProtKB=Q9UMZ2 Q9UMZ2 SYNRG PTHR15463:SF2 AP1 GAMMA SUBUNIT BINDING PROTEIN 1 SYNERGIN GAMMA bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network transport vesicle#GO:0030140;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;plasma membrane#GO:0005886 HUMAN|HGNC=16441|UniProtKB=Q8TDM5 Q8TDM5 SPACA4 PTHR47613:SF1 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 4 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 4 HUMAN|HGNC=7732|UniProtKB=Q15843 Q15843 NEDD8 PTHR10666:SF173 UBIQUITIN NEDD8 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3686|UniProtKB=P55075 P55075 FGF8 PTHR11486:SF3 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 8 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;tube development#GO:0035295;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;embryonic organ development#GO:0048568;embryo development#GO:0009790;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;heart development#GO:0007507;embryonic heart tube development#GO:0035050;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;epithelium development#GO:0060429;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;heart morphogenesis#GO:0003007;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;generation of neurons#GO:0048699;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=15011|UniProtKB=Q8NG80 Q8NG80 OR2L5 PTHR26453:SF166 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2L5 transmembrane signal receptor#PC00197 HUMAN|HGNC=19651|UniProtKB=Q8IYB5 Q8IYB5 SMAP1 PTHR45705:SF8 FI20236P1 STROMAL MEMBRANE-ASSOCIATED PROTEIN 1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of endocytosis#GO:0030100;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;regulation of receptor-mediated endocytosis#GO:0048259 HUMAN|HGNC=28622|UniProtKB=Q8N6G2 Q8N6G2 TEX26 PTHR33769:SF1 TESTIS-EXPRESSED PROTEIN 26 ISOFORM X3 TESTIS-EXPRESSED PROTEIN 26 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=7153|UniProtKB=Q15546 Q15546 MMD PTHR20855:SF26 ADIPOR/PROGESTIN RECEPTOR-RELATED MONOCYTE TO MACROPHAGE DIFFERENTIATION FACTOR G-protein coupled receptor#PC00021 HUMAN|HGNC=30614|UniProtKB=Q7Z5L4 Q7Z5L4 SPATA19 PTHR36468:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 19, MITOCHONDRIAL SPERMATOGENESIS-ASSOCIATED PROTEIN 19, MITOCHONDRIAL HUMAN|HGNC=19147|UniProtKB=Q8N144 Q8N144 GJD3 PTHR11984:SF5 CONNEXIN GAP JUNCTION DELTA-3 PROTEIN gap junction#PC00105 HUMAN|HGNC=29217|UniProtKB=Q9ULL5 Q9ULL5 PRR12 PTHR14709:SF1 UNCHARACTERIZED PROLINE-RICH PROTEIN 12 HUMAN|HGNC=30405|UniProtKB=Q8NF86 Q8NF86 PRSS33 PTHR24256:SF219 TRYPTASE-RELATED SERINE PROTEASE 33 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=2314|UniProtKB=Q99829 Q99829 CPNE1 PTHR10857:SF2 COPINE COPINE-1 calcium-dependent phospholipid binding#GO:0005544;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;response to inorganic substance#GO:0010035;I-kappaB kinase/NF-kappaB signaling#GO:0007249;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;tumor necrosis factor-mediated signaling pathway#GO:0033209;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;response to metal ion#GO:0010038;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=25200|UniProtKB=Q8N365 Q8N365 CIART PTHR35441:SF1 CIRCADIAN-ASSOCIATED TRANSCRIPTIONAL REPRESSOR CIRCADIAN-ASSOCIATED TRANSCRIPTIONAL REPRESSOR sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=7754|UniProtKB=Q92859 Q92859 NEO1 PTHR44170:SF14 PROTEIN SIDEKICK NEOGENIN HUMAN|HGNC=12785|UniProtKB=Q9Y6F9 Q9Y6F9 WNT6 PTHR12027:SF72 WNT RELATED PROTEIN WNT-6 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=14331|UniProtKB=Q9NY87 Q9NY87 SPANXC PTHR23425:SF16 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME A-RELATED HUMAN|HGNC=13108|UniProtKB=P28698 P28698 MZF1 PTHR24384:SF2 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED MYELOID ZINC FINGER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=16231|UniProtKB=Q9NTU7 Q9NTU7 CBLN4 PTHR22923:SF3 CEREBELLIN-RELATED CEREBELLIN-4 HUMAN|HGNC=25737|UniProtKB=Q9H9Q4 Q9H9Q4 NHEJ1 PTHR32235:SF1 NON-HOMOLOGOUS END-JOINING FACTOR 1 NON-HOMOLOGOUS END-JOINING FACTOR 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=32594|UniProtKB=Q8TCU6 Q8TCU6 PREX1 PTHR22829:SF6 DEP DOMAIN PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 1 PROTEIN guanyl-nucleotide exchange factor#PC00113 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GEF#P00875 HUMAN|HGNC=18405|UniProtKB=Q8IZT9 Q8IZT9 FAM9C PTHR19368:SF6 XLR/SCP3/FAM9 PROTEIN FAM9C male gamete generation#GO:0048232;cellular process involved in reproduction in multicellular organism#GO:0022412;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;spermatid differentiation#GO:0048515;cell differentiation#GO:0030154;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;meiotic cell cycle#GO:0051321;multicellular organism reproduction#GO:0032504;cellular component organization#GO:0016043;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;cell cycle#GO:0007049 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=10626|UniProtKB=Q9Y4X3 Q9Y4X3 CCL27 PTHR17502:SF4 C-C MOTIF CHEMOKINE 27 FAMILY MEMBER C-C MOTIF CHEMOKINE 27 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 positive regulation of organelle organization#GO:0010638;actin cytoskeleton reorganization#GO:0031532;regulation of locomotion#GO:0040012;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;positive regulation of cellular component movement#GO:0051272;positive regulation of leukocyte migration#GO:0002687;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;leukocyte migration#GO:0050900;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;regulation of leukocyte migration#GO:0002685;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of immune system process#GO:0002682;regulation of actin filament-based process#GO:0032970;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;chemotaxis#GO:0006935;regulation of cellular component movement#GO:0051270;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;regulation of organelle organization#GO:0033043;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;positive regulation of immune system process#GO:0002684;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;cell chemotaxis#GO:0060326;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of cell migration#GO:0030335;lymphocyte migration#GO:0072676;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;positive regulation of cellular component organization#GO:0051130;positive regulation of cytoskeleton organization#GO:0051495;positive regulation of leukocyte chemotaxis#GO:0002690;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=1371|UniProtKB=O43570 O43570 CA12 PTHR18952:SF19 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 12 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=2077|UniProtKB=Q9NWW5 Q9NWW5 CLN6 PTHR16244:SF2 CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 6 CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 6 HUMAN|HGNC=26395|UniProtKB=Q8N6N2 Q8N6N2 TTC9B PTHR43811:SF12 FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA TETRATRICOPEPTIDE REPEAT PROTEIN 9B chaperone#PC00072 HUMAN|HGNC=18285|UniProtKB=Q96S21 Q96S21 RAB40C PTHR47980:SF2 LD44762P RAS-RELATED PROTEIN RAB-40C vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;protein secretion#GO:0009306;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=6260|UniProtKB=Q9UNX9 Q9UNX9 KCNJ14 PTHR11767:SF40 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 14 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=11033|UniProtKB=Q9Y6M7 Q9Y6M7 SLC4A7 PTHR11453:SF105 ANION EXCHANGE PROTEIN SODIUM BICARBONATE COTRANSPORTER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=30347|UniProtKB=Q9NVU0 Q9NVU0 POLR3E PTHR12069:SF0 DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;intracellular#GO:0005622;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;transferase complex#GO:1990234;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=5633|UniProtKB=A0A075B7D8 A0A075B7D8 IGHV3OR15-7 PTHR23266:SF346 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=16119|UniProtKB=Q9NUG6 Q9NUG6 PDRG1 PTHR21162:SF0 P53 AND DNA DAMAGE-REGULATED PROTEIN P53 AND DNA DAMAGE-REGULATED PROTEIN 1 HUMAN|HGNC=27915|UniProtKB=Q8IYL3 Q8IYL3 C1orf174 PTHR28491:SF1 UPF0688 PROTEIN C1ORF174 UPF0688 PROTEIN C1ORF174 HUMAN|HGNC=400|UniProtKB=Q13740 Q13740 ALCAM PTHR11973:SF2 CELL SURFACE GLYCOPROTEIN MUC18-RELATED CD166 ANTIGEN immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=19421|UniProtKB=Q8WYH8 Q8WYH8 ING5 PTHR10333:SF41 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 5 protein binding#GO:0005515;methylated histone binding#GO:0035064;binding#GO:0005488;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=12680|UniProtKB=P15692 P15692 VEGFA PTHR12025:SF5 VASCULAR ENDOTHELIAL GROWTH FACTOR VASCULAR ENDOTHELIAL GROWTH FACTOR A receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein metabolic process#GO:0051246;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;positive regulation of protein modification process#GO:0031401;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;tube morphogenesis#GO:0035239;epithelial cell proliferation#GO:0050673;sprouting angiogenesis#GO:0002040;positive regulation of epithelial cell proliferation#GO:0050679;cellular protein metabolic process#GO:0044267;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;angiogenesis#GO:0001525;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;taxis#GO:0042330;signal transduction#GO:0007165;response to hypoxia#GO:0001666;positive regulation of angiogenesis#GO:0045766;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of leukocyte migration#GO:0002687;system development#GO:0048731;regulation of chemotaxis#GO:0050920;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;myeloid leukocyte migration#GO:0097529;regulation of immune system process#GO:0002682;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;response to oxygen levels#GO:0070482;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;positive regulation of immune system process#GO:0002684;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cell chemotaxis#GO:0060326;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;positive regulation of cellular component movement#GO:0051272;regulation of phosphorus metabolic process#GO:0051174;leukocyte migration#GO:0050900;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;nitrogen compound metabolic process#GO:0006807;vasculature development#GO:0001944;response to abiotic stimulus#GO:0009628;leukocyte chemotaxis#GO:0030595;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;response to decreased oxygen levels#GO:0036293;tube development#GO:0035295;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;positive chemotaxis#GO:0050918;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;developmental process#GO:0032502;endothelial cell proliferation#GO:0001935;regulation of angiogenesis#GO:0045765;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;positive regulation of developmental process#GO:0051094;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of leukocyte chemotaxis#GO:0002690;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 VEGF signaling pathway#P00056>VEGF#P01406;Angiogenesis#P00005>VEGF#P00241 HUMAN|HGNC=29616|UniProtKB=Q8N137 Q8N137 CNTROB PTHR34439:SF1 CENTROBIN CENTROBIN cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell division#GO:0051301;membrane fission#GO:0090148;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;microtubule organizing center organization#GO:0031023;mitotic cell cycle process#GO:1903047;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=8746|UniProtKB=Q6UW60 Q6UW60 PCSK4 PTHR42884:SF16 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 4 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 HUMAN|HGNC=1445|UniProtKB=P0DP24 P0DP24 CALM2 PTHR23050:SF383 CALCIUM BINDING PROTEIN CALMODULIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 calmodulin-related#PC00061 B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716;T cell activation#P00053>Calmodulin#P01305 HUMAN|HGNC=21710|UniProtKB=Q6ZT07 Q6ZT07 TBC1D9 PTHR22957:SF536 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 9 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=4883|UniProtKB=P08603 P08603 CFH PTHR45785:SF7 COMPLEMENT FACTOR H-RELATED COMPLEMENT FACTOR H HUMAN|HGNC=24309|UniProtKB=O95232 O95232 LUC7L3 PTHR12375:SF47 RNA-BINDING PROTEIN LUC7-RELATED LUC7-LIKE PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=10496|UniProtKB=P06703 P06703 S100A6 PTHR11639:SF80 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A6 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;extracellular matrix#GO:0031012;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;organelle#GO:0043226;intracellular organelle#GO:0043229 calmodulin-related#PC00061 HUMAN|HGNC=20630|UniProtKB=Q96IQ9 Q96IQ9 ZNF414 PTHR21695:SF0 UNCHARACTERIZED ZINC FINGER PROTEIN 414 HUMAN|HGNC=2652|UniProtKB=O75881 O75881 CYP7B1 PTHR24304:SF0 CYTOCHROME P450 FAMILY 7 CYTOCHROME P450 7B1 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 organic acid biosynthetic process#GO:0016053;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;chemical homeostasis#GO:0048878;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;cholesterol homeostasis#GO:0042632;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;steroid biosynthetic process#GO:0006694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 oxygenase#PC00177 HUMAN|HGNC=12124|UniProtKB=A0A0B4J265 A0A0B4J265 TRAV26-2 PTHR19433:SF86 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 26-2 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=30905|UniProtKB=Q49A92 Q49A92 C8orf34 PTHR32000:SF3 SIMILAR TO HYPOTHETICAL PROTEIN SIMILAR TO HYPOTHETICAL PROTEIN HUMAN|HGNC=23207|UniProtKB=Q5UIP0 Q5UIP0 RIF1 PTHR22928:SF3 TELOMERE-ASSOCIATED PROTEIN RIF1 TELOMERE-ASSOCIATED PROTEIN RIF1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 HUMAN|HGNC=23248|UniProtKB=Q3SYC2 Q3SYC2 MOGAT2 PTHR12317:SF74 DIACYLGLYCEROL O-ACYLTRANSFERASE 2-ACYLGLYCEROL O-ACYLTRANSFERASE 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=27901|UniProtKB=Q5BKU9 Q5BKU9 OXLD1 PTHR21193:SF3 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176 HUMAN|HGNC=25934|UniProtKB=Q8N594 Q8N594 MPND PTHR12802:SF46 SWI/SNF COMPLEX-RELATED MPN DOMAIN-CONTAINING PROTEIN membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=10555|UniProtKB=Q99700 Q99700 ATXN2 PTHR12854:SF11 ATAXIN 2-RELATED ATAXIN-2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;cytoplasmic mRNA processing body assembly#GO:0033962;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 HUMAN|HGNC=2649|UniProtKB=Q16850 Q16850 CYP51A1 PTHR24286:SF191 CYTOCHROME P450 26 LANOSTEROL 14-ALPHA DEMETHYLASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;oxidation-reduction process#GO:0055114;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177 HUMAN|HGNC=18466|UniProtKB=O60930 O60930 RNASEH1 PTHR10642:SF23 RIBONUCLEASE H1 RIBONUCLEASE H1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;cellular catabolic process#GO:0044248 endoribonuclease#PC00094 DNA replication#P00017>RNase H#P00538 HUMAN|HGNC=23616|UniProtKB=Q8IY50 Q8IY50 SLC35F3 PTHR19346:SF3 UNCHARACTERIZED THIAMINE TRANSPORTER SLC35F3-RELATED HUMAN|HGNC=13540|UniProtKB=O75110 O75110 ATP9A PTHR24092:SF49 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IIA-RELATED pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;vesicle budding from membrane#GO:0006900;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;vesicle organization#GO:0016050;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=13631|UniProtKB=Q9Y3U8 Q9Y3U8 RPL36 PTHR10114:SF28 60S RIBOSOMAL PROTEIN L36 60S RIBOSOMAL PROTEIN L36 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=29935|UniProtKB=Q9BXB7 Q9BXB7 SPATA16 PTHR47228:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 16 SPERMATOGENESIS-ASSOCIATED PROTEIN 16 developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;multi-organism process#GO:0051704;multicellular organismal reproductive process#GO:0048609 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=6030|UniProtKB=Q01113 Q01113 IL9R PTHR23037:SF29 CYTOKINE RECEPTOR INTERLEUKIN-9 RECEPTOR transmembrane signal receptor#PC00197 HUMAN|HGNC=11874|UniProtKB=Q9NZQ9 Q9NZQ9 TMOD4 PTHR10901:SF9 TROPOMODULIN TROPOMODULIN-4 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular component assembly involved in morphogenesis#GO:0010927;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;myofibril assembly#GO:0030239;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component morphogenesis#GO:0032989;muscle cell development#GO:0055001;cell development#GO:0048468;organelle assembly#GO:0070925;muscle structure development#GO:0061061;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;organelle organization#GO:0006996;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=26683|UniProtKB=Q8N9Z9 Q8N9Z9 LMNTD1 PTHR47012:SF1 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 1 LAMIN TAIL DOMAIN-CONTAINING PROTEIN 1 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=8979|UniProtKB=P27986 P27986 PIK3R1 PTHR10155:SF3 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;regulation of catalytic activity#GO:0050790;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;regulation of molecular function#GO:0065009;cellular response to insulin stimulus#GO:0032869;phosphorylation#GO:0016310;signaling#GO:0023052;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;regulation of lipid metabolic process#GO:0019216;cellular lipid metabolic process#GO:0044255;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;phosphatidylinositol phosphorylation#GO:0046854;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 PDGF signaling pathway#P00047>PI3K#P01168;PI3 kinase pathway#P00048>p85#P01202;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;VEGF signaling pathway#P00056>PI3K#P01413;CCKR signaling map#P06959>p85#P07212;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936;Gonadotropin-releasing hormone receptor pathway#P06664>PI3K#P06766 HUMAN|HGNC=10773|UniProtKB=P31947 P31947 SFN PTHR18860:SF14 14-3-3 PROTEIN 14-3-3 PROTEIN SIGMA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;p53 pathway#P00059>14-3-3#P04628;EGF receptor signaling pathway#P00018>14-3-3#P00539;p53 pathway#P00059>14-3-3#G01576 HUMAN|HGNC=20309|UniProtKB=Q9Y2L9 Q9Y2L9 LRCH1 PTHR16083:SF10 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 1 negative regulation of biological process#GO:0048519;response to cytokine#GO:0034097;regulation of locomotion#GO:0040012;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;regulation of leukocyte migration#GO:0002685;regulation of immune system process#GO:0002682;negative regulation of cell motility#GO:2000146;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of cellular component movement#GO:0051270;response to organic substance#GO:0010033;negative regulation of locomotion#GO:0040013;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;immune system process#GO:0002376;lymphocyte migration#GO:0072676;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of immune system process#GO:0002683;cell migration#GO:0016477;locomotion#GO:0040011 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=28950|UniProtKB=Q15053 Q15053 KIAA0040 PTHR40382:SF1 FAMILY NOT NAMED RIKEN CDNA 4930523C07 GENE HUMAN|HGNC=26955|UniProtKB=Q9UFB7 Q9UFB7 ZBTB47 PTHR24394:SF24 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 47 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=31673|UniProtKB=A8MXD5 A8MXD5 GRXCR1 PTHR46990:SF1 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 1 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 1 oxidoreductase#PC00176 HUMAN|HGNC=8661|UniProtKB=Q9HC56 Q9HC56 PCDH9 PTHR24028:SF248 CADHERIN-87A PROTOCADHERIN-9 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=16994|UniProtKB=Q13438 Q13438 OS9 PTHR15414:SF5 OS-9-RELATED PROTEIN OS-9 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;modification-dependent macromolecule catabolic process#GO:0043632;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;ubiquitin-dependent ERAD pathway#GO:0030433;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=25559|UniProtKB=Q9HCM1 Q9HCM1 RESF1 PTHR21604:SF0 UNCHARACTERIZED RETROELEMENT SILENCING FACTOR 1 HUMAN|HGNC=8349|UniProtKB=Q8NHB7 Q8NHB7 OR5K1 PTHR26452:SF829 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5K1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=13815|UniProtKB=Q9HAY6 Q9HAY6 BCO1 PTHR10543:SF132 BETA-CAROTENE DIOXYGENASE BETA,BETA-CAROTENE 15,15'-DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 oxygenase#PC00177 HUMAN|HGNC=1085|UniProtKB=O60238 O60238 BNIP3L PTHR15186:SF3 RE48077P BCL2/ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3-LIKE response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;apoptotic mitochondrial changes#GO:0008637;membrane organization#GO:0061024;transport#GO:0006810;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;apoptotic process#GO:0006915;cell death#GO:0008219;mitochondrion organization#GO:0007005;defense response to virus#GO:0051607;regulation of membrane permeability#GO:0090559;defense response#GO:0006952;signaling#GO:0023052;immune effector process#GO:0002252;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;interspecies interaction between organisms#GO:0044419;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;organelle organization#GO:0006996;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;regulation of mitochondrial membrane permeability#GO:0046902;biological regulation#GO:0065007;regulation of cell death#GO:0010941;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=15955|UniProtKB=Q53EL9 Q53EL9 SEZ6 PTHR45656:SF1 PROTEIN CBR-CLEC-78 SEIZURE PROTEIN 6 HOMOLOG HUMAN|HGNC=51262|UniProtKB=P0DMV2 P0DMV2 CT45A9 PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED CANCER/TESTIS ANTIGEN FAMILY 45 MEMBER A1-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 RNA helicase#PC00032 HUMAN|HGNC=3471|UniProtKB=P11474 P11474 ESRRA PTHR48092:SF15 KNIRPS-RELATED PROTEIN-RELATED STEROID HORMONE RECEPTOR ERR1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Gonadotropin-releasing hormone receptor pathway#P06664>ER#P06851 HUMAN|HGNC=3113|UniProtKB=Q01094 Q01094 E2F1 PTHR12081:SF43 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;mitotic cell cycle phase transition#GO:0044772;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;cell cycle process#GO:0022402;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=14857|UniProtKB=Q9UP83 Q9UP83 COG5 PTHR13228:SF3 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;intra-Golgi vesicle-mediated transport#GO:0006891;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=29822|UniProtKB=Q9Y6X6 Q9Y6X6 MYO16 PTHR47335:SF1 UNCONVENTIONAL MYOSIN-XVI UNCONVENTIONAL MYOSIN-XVI Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=28716|UniProtKB=Q8IYJ2 Q8IYJ2 C10orf67 PTHR22382:SF7 RIKEN CDNA 4921504E06 GENE RIKEN CDNA 4921504E06 GENE HUMAN|HGNC=2310|UniProtKB=Q6PUV4 Q6PUV4 CPLX2 PTHR16705:SF9 COMPLEXIN COMPLEXIN-2 syntaxin binding#GO:0019905;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488;syntaxin-1 binding#GO:0017075 vesicle fusion#GO:0006906;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of secretion#GO:0051046;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;cell junction#GO:0030054;SNARE complex#GO:0031201;terminal bouton#GO:0043195;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=25854|UniProtKB=Q9H841 Q9H841 NIPAL2 PTHR12570:SF16 UNCHARACTERIZED NIPA-LIKE PROTEIN 2 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=33194|UniProtKB=A6NJT0 A6NJT0 UNCX PTHR46799:SF1 HOMEOBOX PROTEIN UNC-4 HOMOLOG HOMEOBOX PROTEIN UNC-4 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 homeodomain transcription factor#PC00119 HUMAN|HGNC=5125|UniProtKB=P31276 P31276 HOXC13 PTHR45804:SF5 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-C13 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=12737|UniProtKB=Q96G27 Q96G27 WBP1 PTHR16209:SF5 FAMILY NOT NAMED WW DOMAIN-BINDING PROTEIN 1 HUMAN|HGNC=25478|UniProtKB=Q8N565 Q8N565 MREG PTHR34340:SF3 FAMILY NOT NAMED MELANOREGULIN cellular developmental process#GO:0048869;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;developmental process#GO:0032502;pigmentation#GO:0043473;cellular process#GO:0009987;localization#GO:0051179;cell differentiation#GO:0030154;developmental pigmentation#GO:0048066;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;establishment of localization in cell#GO:0051649;melanocyte differentiation#GO:0030318;establishment of organelle localization#GO:0051656 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=22042|UniProtKB=Q8N8L6 Q8N8L6 ARL10 PTHR47575:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 10 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 10 HUMAN|HGNC=13752|UniProtKB=Q9NP98 Q9NP98 MYOZ1 PTHR15941:SF11 MYOZENIN MYOZENIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 supramolecular complex#GO:0099080;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 non-motor actin binding protein#PC00165 HUMAN|HGNC=6629|UniProtKB=Q6P1M3 Q6P1M3 LLGL2 PTHR10241:SF20 LETHAL 2 GIANT LARVAE PROTEIN LLGL SCRIBBLE CELL POLARITY COMPLEX COMPONENT 2 GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;myosin binding#GO:0017022;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;syntaxin binding#GO:0019905;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;SNARE binding#GO:0000149 cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;protein secretion#GO:0009306;regulation of localization#GO:0032879;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of secretion#GO:0051046;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;regulation of protein localization#GO:0032880;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;regulation of protein secretion#GO:0050708;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;regulation of establishment of protein localization#GO:0070201;export from cell#GO:0140352;regulation of peptide transport#GO:0090087;establishment or maintenance of cell polarity#GO:0007163;vesicle fusion#GO:0006906;signal transduction#GO:0007165;macromolecule localization#GO:0033036;regulation of signaling#GO:0023051;establishment of spindle orientation#GO:0051294;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;peptide secretion#GO:0002790;regulation of Notch signaling pathway#GO:0008593;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;vesicle organization#GO:0016050;regulation of protein transport#GO:0051223;signaling#GO:0023052;spindle localization#GO:0051653;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;localization#GO:0051179;response to stimulus#GO:0050896;membrane fusion#GO:0061025;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;actin cytoskeleton organization#GO:0030036;cortical actin cytoskeleton organization#GO:0030866;Notch signaling pathway#GO:0007219 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=9394|UniProtKB=Q9NRD5 Q9NRD5 PICK1 PTHR12141:SF1 ARFAPTIN-RELATED PRKCA-BINDING PROTEIN binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;kinase binding#GO:0019900 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;positive regulation of supramolecular fiber organization#GO:1902905;membrane organization#GO:0061024;positive regulation of cellular metabolic process#GO:0031325;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;regulation of endocytosis#GO:0030100;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;peptide transport#GO:0015833;positive regulation of macromolecule metabolic process#GO:0010604;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein transport#GO:0015031;intracellular transport#GO:0046907;regulation of metabolic process#GO:0019222;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular metabolic process#GO:0031323;receptor internalization#GO:0031623;macromolecule localization#GO:0033036;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;regulation of protein-containing complex assembly#GO:0043254;supramolecular fiber organization#GO:0097435;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;vesicle organization#GO:0016050;regulation of actin filament-based process#GO:0032970;receptor-mediated endocytosis#GO:0006898;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;metabolic process#GO:0008152;regulation of anatomical structure size#GO:0090066;protein localization to membrane#GO:0072657;regulation of actin filament length#GO:0030832;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;positive regulation of protein-containing complex assembly#GO:0031334;regulation of cellular component size#GO:0032535;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;vesicle budding from membrane#GO:0006900;Arp2/3 complex-mediated actin nucleation#GO:0034314;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;actin cytoskeleton organization#GO:0030036;receptor clustering#GO:0043113 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 vesicle coat protein#PC00235 Ionotropic glutamate receptor pathway#P00037>PICK#P01012 HUMAN|HGNC=1955|UniProtKB=P02708 P02708 CHRNA1 PTHR18945:SF74 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=21233|UniProtKB=Q5T5N4 Q5T5N4 C6orf118 PTHR34916:SF1 GI:13385330 TSNAXIP1_N DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=4741|UniProtKB=P0C0S5 P0C0S5 H2AZ1 PTHR23430:SF47 HISTONE H2A HISTONE H2A.Z heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=2905|UniProtKB=O14490 O14490 DLGAP1 PTHR12353:SF7 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 1 molecular adaptor activity#GO:0060090;binding#GO:0005488 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;regulation of neurotransmitter receptor activity#GO:0099601;chemical synaptic transmission, postsynaptic#GO:0099565;system process#GO:0003008;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;regulation of system process#GO:0044057;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;signaling#GO:0023052 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;postsynapse#GO:0098794;synapse#GO:0045202;postsynaptic specialization#GO:0099572;cellular anatomical entity#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26876|UniProtKB=Q460N3 Q460N3 PARP15 PTHR14453:SF97 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP15 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription corepressor activity#GO:0003714 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;gene expression#GO:0010467;negative regulation of metabolic process#GO:0009892;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28159|UniProtKB=Q3B7J2 Q3B7J2 GFOD2 PTHR43818:SF8 BCDNA.GH03377 GLUCOSE-FRUCTOSE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 dehydrogenase#PC00092 HUMAN|HGNC=5816|UniProtKB=P01624 P01624 IGKV3-15 PTHR23267:SF331 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=11800|UniProtKB=Q92748 Q92748 THRSP PTHR14315:SF18 SPOT14 FAMILY MEMBER THYROID HORMONE-INDUCIBLE HEPATIC PROTEIN regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;lipid metabolic process#GO:0006629;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;lipid biosynthetic process#GO:0008610;regulation of metabolic process#GO:0019222;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=18961|UniProtKB=Q8WTU0 Q8WTU0 DDI1 PTHR12917:SF15 ASPARTYL PROTEASE DDI-RELATED PROTEIN DDI1 HOMOLOG 1 aspartic protease#PC00053 HUMAN|HGNC=20516|UniProtKB=Q6DN03 Q6DN03 H2BC20P PTHR23428:SF298 HISTONE H2B HISTONE H2B TYPE 2-C-RELATED nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=10253|UniProtKB=O95758 O95758 PTBP3 PTHR15592:SF17 MATRIN 3/NUCLEAR PROTEIN 220-RELATED POLYPYRIMIDINE TRACT-BINDING PROTEIN 3 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;RNA splicing#GO:0008380;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;biosynthetic process#GO:0009058;translation#GO:0006412;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=27949|UniProtKB=Q6ZQY3 Q6ZQY3 GADL1 PTHR45677:SF1 GLUTAMATE DECARBOXYLASE-RELATED ACIDIC AMINO ACID DECARBOXYLASE GADL1 decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 HUMAN|HGNC=12547|UniProtKB=O75795 O75795 UGT2B17 PTHR48043:SF12 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2B17-RELATED transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=14265|UniProtKB=Q86UP0 Q86UP0 CDH24 PTHR24027:SF272 CADHERIN-23 CADHERIN-24 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=12799|UniProtKB=Q9NZC7 Q9NZC7 WWOX PTHR24320:SF197 RETINOL DEHYDROGENASE WW DOMAIN-CONTAINING OXIDOREDUCTASE dehydrogenase#PC00092 HUMAN|HGNC=7373|UniProtKB=P26038 P26038 MSN PTHR23281:SF26 MERLIN/MOESIN/EZRIN/RADIXIN MOESIN actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=14783|UniProtKB=Q8WZ92 Q8WZ92 OR5P2 PTHR26452:SF90 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5P2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=29905|UniProtKB=O75534 O75534 CSDE1 PTHR12913:SF1 UNR PROTEIN N-RAS UPSTREAM GENE PROTEIN COLD SHOCK DOMAIN-CONTAINING PROTEIN E1 HUMAN|HGNC=16015|UniProtKB=Q9H8S9 Q9H8S9 MOB1A PTHR22599:SF30 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 1A kinase activator#PC00138 CCKR signaling map#P06959>MOB1#G07283;CCKR signaling map#P06959>MOB1#G06990 HUMAN|HGNC=2049|UniProtKB=O95471 O95471 CLDN7 PTHR12002:SF78 CLAUDIN CLAUDIN-7 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=5399|UniProtKB=P80217 P80217 IFI35 PTHR15225:SF1 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN INTERFERON-INDUCED 35 KDA PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 transcription cofactor#PC00217 HUMAN|HGNC=11652|UniProtKB=P20061 P20061 TCN1 PTHR10559:SF13 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR TRANSCOBALAMIN-1 tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159 localization#GO:0051179;nitrogen compound transport#GO:0071705;organic substance transport#GO:0071702;establishment of localization#GO:0051234;transport#GO:0006810 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=7051|UniProtKB=O75556 O75556 SCGB2A1 PTHR14037:SF4 MAMMAGLOBIN-RELATED MAMMAGLOBIN-B response to organic substance#GO:0010033;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cellular response to steroid hormone stimulus#GO:0071383;response to lipid#GO:0033993;cell communication#GO:0007154;steroid hormone mediated signaling pathway#GO:0043401;cellular process#GO:0009987;cellular response to lipid#GO:0071396;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;intracellular steroid hormone receptor signaling pathway#GO:0030518;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;signaling#GO:0023052;response to steroid hormone#GO:0048545 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=14034|UniProtKB=Q9BZE1 Q9BZE1 MRPL37 PTHR15889:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L37 39S RIBOSOMAL PROTEIN L37, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ribosomal protein#PC00202 HUMAN|HGNC=4624|UniProtKB=P48637 P48637 GSS PTHR11130:SF0 GLUTATHIONE SYNTHETASE GLUTATHIONE SYNTHETASE ligase activity#GO:0016874;anion binding#GO:0043168;ion binding#GO:0043167;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;peptide binding#GO:0042277 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 HUMAN|HGNC=35118|UniProtKB=A8MZF0 A8MZF0 PRR33 PTHR38004:SF1 PROLINE-RICH PROTEIN 33 PROLINE-RICH PROTEIN 33 HUMAN|HGNC=29569|UniProtKB=Q9Y234 Q9Y234 LIPT1 PTHR12561:SF3 LIPOATE-PROTEIN LIGASE LIPOYLTRANSFERASE 1, MITOCHONDRIAL transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein modifying enzyme#PC00260 HUMAN|Ensembl=ENSG00000206463|UniProtKB=A0A140T8X8 A0A140T8X8 MUC21 PTHR39408:SF3 MUCIN-21 MUCIN-21 HUMAN|HGNC=4045|UniProtKB=O75084 O75084 FZD7 PTHR11309:SF31 FRIZZLED FRIZZLED-7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119 HUMAN|HGNC=15454|UniProtKB=Q9UQ13 Q9UQ13 SHOC2 PTHR45752:SF26 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT PROTEIN SHOC-2 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;regulation of Ras protein signal transduction#GO:0046578;signaling#GO:0023052;positive regulation of biological process#GO:0048518 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17827|UniProtKB=O15466 O15466 ST8SIA5 PTHR11987:SF4 ALPHA-2,8-SIALYLTRANSFERASE ALPHA-2,8-SIALYLTRANSFERASE 8E transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=8853|UniProtKB=O96011 O96011 PEX11B PTHR12652:SF7 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11B regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;biological regulation#GO:0065007;organelle fission#GO:0048285;cellular component organization#GO:0016043;cellular process#GO:0009987;peroxisome organization#GO:0007031;regulation of cellular component size#GO:0032535 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;microbody membrane#GO:0031903;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 HUMAN|HGNC=20910|UniProtKB=Q63HM1 Q63HM1 AFMID PTHR23024:SF574 ARYLACETAMIDE DEACETYLASE KYNURENINE FORMAMIDASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 deacetylase#PC00087 HUMAN|HGNC=1408|UniProtKB=Q9UBN1 Q9UBN1 CACNG4 PTHR12107:SF7 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-4 SUBUNIT calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;cation channel activity#GO:0005261;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 cellular localization#GO:0051641;membrane organization#GO:0061024;system process#GO:0003008;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;anterograde trans-synaptic signaling#GO:0098916;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;regulation of transmembrane transporter activity#GO:0022898;positive regulation of signaling#GO:0023056;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;establishment of protein localization to vacuole#GO:0072666;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;protein localization to synapse#GO:0035418;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of ion transmembrane transport#GO:0034765;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein localization to cell junction#GO:1902414;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;regulation of trans-synaptic signaling#GO:0099177;regulation of ion transport#GO:0043269;multicellular organismal process#GO:0032501;protein-containing complex localization#GO:0031503;receptor localization to synapse#GO:0097120;signal transduction#GO:0007165;regulation of neurotransmitter receptor activity#GO:0099601;receptor internalization#GO:0031623;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;action potential#GO:0001508;cation transport#GO:0006812;ionotropic glutamate receptor signaling pathway#GO:0035235;cation transmembrane transport#GO:0098655;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;vacuolar transport#GO:0007034;protein localization to membrane#GO:0072657;regulation of membrane potential#GO:0042391;protein localization to vacuole#GO:0072665;ion transport#GO:0006811;establishment of protein localization to organelle#GO:0072594;regulation of AMPA receptor activity#GO:2000311;nervous system process#GO:0050877;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;protein localization to cell periphery#GO:1990778;localization#GO:0051179;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of synaptic transmission#GO:0050806;synaptic transmission, glutamatergic#GO:0035249 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;organelle#GO:0043226;integral component of membrane#GO:0016021;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=4482|UniProtKB=Q9NS67 Q9NS67 GPR27 PTHR19268:SF8 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 27-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=2745|UniProtKB=O00571 O00571 DDX3X PTHR47958:SF4 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX3X catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;cellular process#GO:0009987;multi-organism reproductive process#GO:0044703;multi-organism process#GO:0051704;multicellular organismal reproductive process#GO:0048609 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=18622|UniProtKB=P83436 P83436 COG7 PTHR21443:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;establishment of localization#GO:0051234;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=25405|UniProtKB=Q6ZUS6 Q6ZUS6 CCDC149 PTHR21682:SF2 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 149 HUMAN|HGNC=28216|UniProtKB=Q96I36 Q96I36 COX14 PTHR36684:SF1 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX14 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX14 chaperone#PC00072 HUMAN|HGNC=18624|UniProtKB=Q9NYL4 Q9NYL4 FKBP11 PTHR45779:SF2 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP11 HUMAN|HGNC=324|UniProtKB=Q99943 Q99943 AGPAT1 PTHR10434:SF56 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE ALPHA transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=12755|UniProtKB=Q9UNX4 Q9UNX4 WDR3 PTHR19853:SF0 WD REPEAT CONTAINING PROTEIN 3 WDR3 WD REPEAT-CONTAINING PROTEIN 3 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 HUMAN|HGNC=24278|UniProtKB=Q5VST6 Q5VST6 ABHD17B PTHR12277:SF48 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17B hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 macromolecule catabolic process#GO:0009057;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;macromolecule deacylation#GO:0098732;protein deacylation#GO:0035601;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;lipoprotein metabolic process#GO:0042157;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=17218|UniProtKB=Q9NSJ1 Q9NSJ1 ZNF355P PTHR24377:SF938 IP01015P-RELATED ZINC FINGER PROTEIN 429-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=21376|UniProtKB=Q5VVH2 Q5VVH2 FKBP1C PTHR10516:SF301 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A-RELATED chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 HUMAN|HGNC=27097|UniProtKB=A6NFN3 A6NFN3 RBFOX3 PTHR15597:SF25 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA BINDING PROTEIN FOX-1 HOMOLOG 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;developmental process#GO:0032502;RNA processing#GO:0006396;gene expression#GO:0010467;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;multicellular organismal process#GO:0032501;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=9840|UniProtKB=P11234 P11234 RALB PTHR24070:SF199 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-B GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 Ras Pathway#P04393>Ral#P04550 HUMAN|HGNC=29564|UniProtKB=Q9BSU1 Q9BSU1 C16orf70 PTHR13465:SF2 UPF0183 PROTEIN UPF0183 PROTEIN C16ORF70 HUMAN|HGNC=10946|UniProtKB=Q8WUM9 Q8WUM9 SLC20A1 PTHR11101:SF46 PHOSPHATE TRANSPORTER SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;inorganic anion transport#GO:0015698;anion transmembrane transport#GO:0098656 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=12008|UniProtKB=P17752 P17752 TPH1 PTHR11473:SF23 AROMATIC AMINO ACID HYDROXYLASE TRYPTOPHAN 5-HYDROXYLASE 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 5-Hydroxytryptamine biosynthesis#P04371>Tryptophan hydroxylase#P04399 HUMAN|HGNC=1100|UniProtKB=P38398 P38398 BRCA1 PTHR13763:SF0 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;negative regulation of chromosome organization#GO:2001251;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;positive regulation of protein modification process#GO:0031401;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;carboxylic acid biosynthetic process#GO:0046394;regulation of biological process#GO:0050789;regulation of chromatin organization#GO:1902275;regulation of lipid biosynthetic process#GO:0046890;cellular protein metabolic process#GO:0044267;organic acid biosynthetic process#GO:0016053;negative regulation of cell cycle#GO:0045786;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;double-strand break repair via homologous recombination#GO:0000724;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cell cycle arrest#GO:0007050;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;regulation of lipid metabolic process#GO:0019216;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of cell cycle process#GO:0090068;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;peptidyl-lysine modification#GO:0018205;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;internal peptidyl-lysine acetylation#GO:0018393;fatty acid metabolic process#GO:0006631;positive regulation of protein metabolic process#GO:0051247;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;DNA repair#GO:0006281;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;negative regulation of protein modification process#GO:0031400;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;negative regulation of protein metabolic process#GO:0051248;protein acylation#GO:0043543;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;positive regulation of cellular process#GO:0048522;response to stress#GO:0006950;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;internal protein amino acid acetylation#GO:0006475;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;peptidyl-lysine acetylation#GO:0018394;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;regulation of transcription by RNA polymerase II#GO:0006357;peptidyl-amino acid modification#GO:0018193;regulation of histone modification#GO:0031056;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;fatty acid biosynthetic process#GO:0006633;cellular macromolecule biosynthetic process#GO:0034645;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;nuclear ubiquitin ligase complex#GO:0000152;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=24903|UniProtKB=Q9Y520 Q9Y520 PRRC2C PTHR14038:SF6 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2C cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 RNA metabolism protein#PC00031 HUMAN|HGNC=14477|UniProtKB=Q9H0U6 Q9H0U6 MRPL18 PTHR12899:SF3 39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribosomal protein#PC00202 HUMAN|HGNC=26318|UniProtKB=Q8IYI0 Q8IYI0 SHLD1 PTHR36863:SF1 SHIELDIN COMPLEX SUBUNIT 1 SHIELDIN COMPLEX SUBUNIT 1 HUMAN|HGNC=27295|UniProtKB=Q5VWT5 Q5VWT5 FYB2 PTHR16830:SF1 SH2 CONTAINING ADAPTOR PRAM-1 RELATED FYN-BINDING PROTEIN 2 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;cellular localization#GO:0051641;signal transduction#GO:0007165;activation of immune response#GO:0002253;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;integrin-mediated signaling pathway#GO:0007229;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;signaling#GO:0023052;protein localization to plasma membrane#GO:0072659;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;protein localization to membrane#GO:0072657;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=30238|UniProtKB=Q5T9L3 Q5T9L3 WLS PTHR13449:SF2 INTEGRAL MEMBRANE PROTEIN GPR177 PROTEIN WNTLESS HOMOLOG protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein secretion#GO:0009306;cell communication#GO:0007154;peptide secretion#GO:0002790;peptide transport#GO:0015833;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;signal release#GO:0023061;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;cell-cell signaling#GO:0007267;signaling#GO:0023052;export from cell#GO:0140352;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=3332|UniProtKB=Q7KZI7 Q7KZI7 MARK2 PTHR24346:SF56 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE/THREONINE-PROTEIN KINASE MARK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=25649|UniProtKB=Q9NUL5 Q9NUL5 SHFL PTHR16135:SF2 REPRESSOR OF YIELD OF DENV PROTEIN SHIFTLESS ANTIVIRAL INHIBITOR OF RIBOSOMAL FRAMESHIFTING PROTEIN HUMAN|HGNC=13618|UniProtKB=Q8IX29 Q8IX29 FBXO16 PTHR46857:SF2 EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE F-BOX ONLY PROTEIN 16 HUMAN|HGNC=30833|UniProtKB=O75956 O75956 CDK2AP2 PTHR22607:SF4 DELETED IN ORAL CANCER 1/CDK2-ASSOCIATED PROTEIN 1 CYCLIN-DEPENDENT KINASE 2-ASSOCIATED PROTEIN 2 kinase inhibitor#PC00139 HUMAN|HGNC=11496|UniProtKB=O14994 O14994 SYN3 PTHR10841:SF6 SYNAPSIN SYNAPSIN-3 neurotransmitter secretion#GO:0007269;cellular localization#GO:0051641;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of neurotransmitter levels#GO:0001505;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;signal release#GO:0023061;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;signaling#GO:0023052;cell-cell signaling#GO:0007267;export from cell#GO:0140352;secretion by cell#GO:0032940 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=17095|UniProtKB=Q15031 Q15031 LARS2 PTHR43740:SF2 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=15072|UniProtKB=Q8NHA6 Q8NHA6 OR2W6P PTHR26453:SF21 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2W6-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=8992|UniProtKB=Q9Y237 Q9Y237 PIN4 PTHR45995:SF2 FAMILY NOT NAMED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 4 HUMAN|HGNC=3432|UniProtKB=Q15303 Q15303 ERBB4 PTHR24416:SF90 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;basolateral plasma membrane#GO:0016323;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466;Alzheimer disease-presenilin pathway#P00004>Erb-B4 N-terminal fragment#P00148;Alzheimer disease-presenilin pathway#P00004>Erb-B4#P00128;Alzheimer disease-presenilin pathway#P00004>Erb-B4 C-terminal fragment#P00163;Alzheimer disease-presenilin pathway#P00004>Erb-B4 transmembrane fragment#P00113 HUMAN|HGNC=15988|UniProtKB=Q53F39 Q53F39 MPPE1 PTHR13315:SF0 METALLO PHOSPHOESTERASE RELATED METALLOPHOSPHOESTERASE 1 esterase#PC00097 HUMAN|HGNC=33629|UniProtKB=Q9Y6R9 Q9Y6R9 CCDC61 PTHR22691:SF1 YEAST SPT2-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 61 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=28998|UniProtKB=Q92564 Q92564 DCUN1D4 PTHR12281:SF8 RP42 RELATED DCN1-LIKE PROTEIN 4 enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=26607|UniProtKB=Q2M3R5 Q2M3R5 SLC35G1 PTHR22911:SF127 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G1 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;divalent metal ion transport#GO:0070838;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;export from cell#GO:0140352 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=25849|UniProtKB=Q7L2K0 Q7L2K0 TEDC2 PTHR14870:SF1 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 2 TUBULIN EPSILON AND DELTA COMPLEX PROTEIN 2 HUMAN|HGNC=25819|UniProtKB=Q9H8M1 Q9H8M1 COQ10B PTHR12901:SF9 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG B, MITOCHONDRIAL binding#GO:0005488 cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;small molecule biosynthetic process#GO:0044283;ubiquinone biosynthetic process#GO:0006744;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=21199|UniProtKB=Q96AQ6 Q96AQ6 PBXIP1 PTHR28638:SF1 CELL CYCLE PROGRESSION PROTEIN 1 PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR-INTERACTING PROTEIN 1 HUMAN|HGNC=12776|UniProtKB=O96014 O96014 WNT11 PTHR12027:SF7 WNT RELATED PROTEIN WNT-11 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=17736|UniProtKB=P17081 P17081 RHOQ PTHR24072:SF13 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOQ GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cell projection organization#GO:0030030;membrane organization#GO:0061024;transport#GO:0006810;Ras protein signal transduction#GO:0007265;regulation of biological process#GO:0050789;actin filament-based process#GO:0030029;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle organization#GO:0016050;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;endocytosis#GO:0006897;localization of cell#GO:0051674;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;cell projection assembly#GO:0030031;localization#GO:0051179;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011;cortical actin cytoskeleton organization#GO:0030866 small GTPase#PC00208 Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;Huntington disease#P00029>Rac#P00775;Ras Pathway#P04393>Cdc42#P04569;Axon guidance mediated by netrin#P00009>cdc42#P00364;Integrin signalling pathway#P00034>Cdc42#P00938;EGF receptor signaling pathway#P00018>Rac#P00564;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Axon guidance mediated by Slit/Robo#P00008>Cdc42#P00349 HUMAN|HGNC=3579|UniProtKB=P16930 P16930 FAH PTHR43069:SF2 FUMARYLACETOACETASE FUMARYLACETOACETASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;tyrosine metabolic process#GO:0006570;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;small molecule catabolic process#GO:0044282;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid family metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 HUMAN|HGNC=9652|UniProtKB=Q9Y2R2 Q9Y2R2 PTPN22 PTHR45983:SF1 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 22 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=32250|UniProtKB=Q658T7 Q658T7 FAM90A2P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=4382|UniProtKB=O95837 O95837 GNA14 PTHR10218:SF213 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-14 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 positive regulation of lipase activity#GO:0060193;regulation of adenylate cyclase activity#GO:0045761;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;action potential#GO:0001508;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;chemical synaptic transmission#GO:0007268;dopamine receptor signaling pathway#GO:0007212;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cellular response to organic cyclic compound#GO:0071407;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;cellular response to organic substance#GO:0071310;regulation of phospholipase C activity#GO:1900274;regulation of membrane potential#GO:0042391;positive regulation of phospholipase activity#GO:0010518;trans-synaptic signaling#GO:0099537;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117 Endothelin signaling pathway#P00019>Gq#P00586;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphaq#P00826;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gqalpha#P00732;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Wnt signaling pathway#P00057>Galpha#P01451;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;PI3 kinase pathway#P00048>Galpha#P01199 HUMAN|HGNC=7998|UniProtKB=O14511 O14511 NRG2 PTHR11100:SF20 HEREGULIN-NEUREGULIN FAMILY MEMBER PRO-NEUREGULIN-2, MEMBRANE-BOUND ISOFORM-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;intracellular signal transduction#GO:0035556;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 HUMAN|HGNC=10942|UniProtKB=P43007 P43007 SLC1A4 PTHR11958:SF20 SODIUM/DICARBOXYLATE SYMPORTER-RELATED NEUTRAL AMINO ACID TRANSPORTER A primary active transporter#PC00068 HUMAN|HGNC=4464|UniProtKB=P49683 P49683 PRLHR PTHR24235:SF11 NEUROPEPTIDE Y RECEPTOR PROLACTIN-RELEASING PEPTIDE RECEPTOR G-protein coupled receptor#PC00021 HUMAN|HGNC=24718|UniProtKB=Q96JJ7 Q96JJ7 TMX3 PTHR46426:SF1 PROTEIN DISULFIDE-ISOMERASE TMX3 PROTEIN DISULFIDE-ISOMERASE TMX3 chaperone#PC00072 HUMAN|HGNC=242|UniProtKB=P41586 P41586 ADCYAP1R1 PTHR45620:SF12 PDF RECEPTOR-LIKE PROTEIN-RELATED PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE TYPE I RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Gonadotropin-releasing hormone receptor pathway#P06664>PAC1-R#P06712;Gonadotropin-releasing hormone receptor pathway#P06664>PAC1R#G06685;Gonadotropin-releasing hormone receptor pathway#P06664>PAC1R#G06898 HUMAN|HGNC=33864|UniProtKB=Q3LI81 Q3LI81 KRTAP27-1 PTHR19051:SF5 KERATIN-ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 27-1 structural protein#PC00211 HUMAN|HGNC=2536|UniProtKB=P43235 P43235 CTSK PTHR12411:SF55 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN K cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;immune system process#GO:0002376;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=20188|UniProtKB=Q9NVR5 Q9NVR5 DNAAF2 PTHR22997:SF3 UNCHARACTERIZED PROTEIN KINTOUN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2625|UniProtKB=P10635 P10635 CYP2D6 PTHR24300:SF1 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2D6-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=17721|UniProtKB=Q5TEA3 Q5TEA3 C20orf194 PTHR33664:SF1 RCG26366 RCG26366 HUMAN|HGNC=18665|UniProtKB=Q96BQ1 Q96BQ1 FAM3D PTHR14592:SF9 UNCHARACTERIZED FAM3 PROTEIN FAM3D extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|Ensembl=ENSG00000242120|UniProtKB=A0A1B0GVS7 A0A1B0GVS7 MDFIC2 PTHR15304:SF2 MYOD FAMILY INHIBITOR MYOD FAMILY INHIBITOR DOMAIN-CONTAINING PROTEIN 2 HUMAN|Ensembl=ENSG00000280433|UniProtKB=A0A096LPH7 A0A096LPH7 ENSG00000280433 PTHR13251:SF3 EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;TRAPP complex#GO:0030008;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=30489|UniProtKB=P0C7X2 P0C7X2 ZNF688 PTHR24381:SF297 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 688-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=34396|UniProtKB=P0CE71 P0CE71 OCM2 PTHR11653:SF4 PARVALBUMIN ALPHA ONCOMODULIN-2-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 calmodulin-related#PC00061 HUMAN|HGNC=563|UniProtKB=P63010 P63010 AP2B1 PTHR11134:SF9 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-2 COMPLEX SUBUNIT BETA localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane traffic protein#PC00150 HUMAN|HGNC=1076|UniProtKB=P36894 P36894 BMPR1A PTHR23255:SF50 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1A signaling receptor activity#GO:0038023;SMAD binding#GO:0046332;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;response to BMP#GO:0071772;cellular protein metabolic process#GO:0044267;pattern specification process#GO:0007389;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;multicellular organism development#GO:0007275;BMP signaling pathway#GO:0030509;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 HUMAN|HGNC=24582|UniProtKB=Q5VXD3 Q5VXD3 SAMD13 PTHR12247:SF99 POLYCOMB GROUP PROTEIN ATHERIN-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=5177|UniProtKB=O95081 O95081 AGFG2 PTHR46134:SF4 DRONGO, ISOFORM F ARF-GAP DOMAIN AND FG REPEAT-CONTAINING PROTEIN 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=18005|UniProtKB=Q96F15 Q96F15 GIMAP5 PTHR10903:SF69 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 5 small GTPase#PC00208 HUMAN|HGNC=12298|UniProtKB=P20396 P20396 TRH PTHR17530:SF2 PRO-THYROTROPIN-RELEASING HORMONE PRO-THYROTROPIN-RELEASING HORMONE peptide hormone#PC00179 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH#P04585;Thyrotropin-releasing hormone receptor signaling pathway#P04394>ProTRH (Pro Thyrotropin-releasing Hormone)#P04586 HUMAN|HGNC=16267|UniProtKB=Q9UBV4 Q9UBV4 WNT16 PTHR12027:SF70 WNT RELATED PROTEIN WNT-16 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=21230|UniProtKB=Q9P1F3 Q9P1F3 ABRACL PTHR46334:SF1 COSTARS FAMILY PROTEIN ABRACL COSTARS FAMILY PROTEIN ABRACL biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970;actin filament-based process#GO:0030029;cellular process#GO:0009987;regulation of cellular process#GO:0050794 HUMAN|HGNC=18318|UniProtKB=Q8IXJ9 Q8IXJ9 ASXL1 PTHR13578:SF19 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL1 protein binding#GO:0005515;chromatin binding#GO:0003682;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=30077|UniProtKB=Q00765 Q00765 REEP5 PTHR12300:SF93 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 5 membrane traffic protein#PC00150 HUMAN|HGNC=25790|UniProtKB=Q7L8L6 Q7L8L6 FASTKD5 PTHR21228:SF40 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 5, MITOCHONDRIAL HUMAN|HGNC=25807|UniProtKB=Q96CW6 Q96CW6 SLC7A6OS PTHR31196:SF2 RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED HUMAN|HGNC=28790|UniProtKB=Q9BVG4 Q9BVG4 PBDC1 PTHR13410:SF9 PROTEIN PBDC1 PROTEIN PBDC1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=31959|UniProtKB=Q9UEU5 Q9UEU5 GAGE2D PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=38650|UniProtKB=A6NMD2 A6NMD2 GOLGA8J PTHR10881:SF62 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8H-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=11745|UniProtKB=Q01664 Q01664 TFAP4 PTHR15741:SF27 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR AP-4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=23379|UniProtKB=Q9H756 Q9H756 LRRC19 PTHR31450:SF4 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19 LRRC19 FAMILY MEMBER LEUCINE-RICH REPEAT-CONTAINING PROTEIN 19 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of NIK/NF-kappaB signaling#GO:1901222;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;cytokine production#GO:0001816;positive regulation of response to stimulus#GO:0048584;positive regulation of NIK/NF-kappaB signaling#GO:1901224;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;NIK/NF-kappaB signaling#GO:0038061;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=1541|UniProtKB=P22681 P22681 CBL PTHR23007:SF5 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;regulation of signaling receptor activity#GO:0010469;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857;membrane region#GO:0098589;plasma membrane#GO:0005886;whole membrane#GO:0098805 ligase#PC00142 EGF receptor signaling pathway#P00018>c-Cbl#P00544 HUMAN|HGNC=17425|UniProtKB=Q9GZQ6 Q9GZQ6 NPFFR1 PTHR24241:SF4 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE FF RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=34348|UniProtKB=Q6NT89 Q6NT89 TRNP1 PTHR40714:SF1 TMF-REGULATED NUCLEAR PROTEIN 1 TMF-REGULATED NUCLEAR PROTEIN 1 HUMAN|HGNC=24926|UniProtKB=Q15834 Q15834 CCDC85B PTHR13546:SF12 RE60986P COILED-COIL DOMAIN-CONTAINING PROTEIN 85B negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=1662|UniProtKB=P28906 P28906 CD34 PTHR16677:SF1 HEMATOPOIETIC PROGENITOR CELL ANTIGEN CD34 HEMATOPOIETIC PROGENITOR CELL ANTIGEN CD34 cell adhesion molecule#PC00069 HUMAN|HGNC=395|UniProtKB=P13716 P13716 ALAD PTHR11458:SF0 DELTA-AMINOLEVULINIC ACID DEHYDRATASE DELTA-AMINOLEVULINIC ACID DEHYDRATASE cation binding#GO:0043169;carbon-oxygen lyase activity#GO:0016835;zinc ion binding#GO:0008270;hydro-lyase activity#GO:0016836;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;lyase activity#GO:0016829;ion binding#GO:0043167 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;porphyrin-containing compound metabolic process#GO:0006778;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydratase#PC00091 Heme biosynthesis#P02746>porphobilinogen synthase#P02979 HUMAN|HGNC=2482|UniProtKB=P04080 P04080 CSTB PTHR11414:SF22 CYSTATIN FAMILY MEMBER CYSTATIN-B cysteine-type peptidase activity#GO:0008234;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease inhibitor#PC00191 HUMAN|HGNC=3225|UniProtKB=P52803 P52803 EFNA5 PTHR11304:SF33 EPHRIN EPHRIN-A5 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of cell-cell adhesion#GO:0022407;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of cell adhesion#GO:0030155;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;anchored component of plasma membrane#GO:0046658;intrinsic component of membrane#GO:0031224;intrinsic component of plasma membrane#GO:0031226;anchored component of membrane#GO:0031225;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=30263|UniProtKB=Q9P2J9 Q9P2J9 PDP2 PTHR13832:SF343 PROTEIN PHOSPHATASE 2C [PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=18067|UniProtKB=Q8TD20 Q8TD20 SLC2A12 PTHR48023:SF2 D-XYLOSE-PROTON SYMPORTER-LIKE 2 SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 12 HUMAN|HGNC=1659|UniProtKB=P20138 P20138 CD33 PTHR12035:SF124 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN MYELOID CELL SURFACE ANTIGEN CD33 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=5596|UniProtKB=P01772 P01772 IGHV3-33 PTHR23266:SF241 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=28556|UniProtKB=Q8N0W5 Q8N0W5 IQCK PTHR34927:SF1 IQ DOMAIN-CONTAINING PROTEIN K IQ DOMAIN-CONTAINING PROTEIN K HUMAN|HGNC=9480|UniProtKB=Q9NQE7 Q9NQE7 PRSS16 PTHR11010:SF95 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED THYMUS-SPECIFIC SERINE PROTEASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=20603|UniProtKB=Q86SQ9 Q86SQ9 DHDDS PTHR10291:SF43 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=25422|UniProtKB=Q4VNC1 Q4VNC1 ATP13A4 PTHR45630:SF1 CATION-TRANSPORTING ATPASE-RELATED CATION-TRANSPORTING ATPASE 13A4-RELATED cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 HUMAN|HGNC=29313|UniProtKB=Q9HCK1 Q9HCK1 ZDBF2 PTHR21639:SF5 UNCHARACTERIZED DBF4-TYPE ZINC FINGER-CONTAINING PROTEIN 2 HUMAN|HGNC=24969|UniProtKB=Q8WTW4 Q8WTW4 NPRL2 PTHR12991:SF10 NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4 GATOR COMPLEX PROTEIN NPRL2 cellular component biogenesis#GO:0044085;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of macroautophagy#GO:0016241;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;regulation of autophagosome assembly#GO:2000785;process utilizing autophagic mechanism#GO:0061919;positive regulation of metabolic process#GO:0009893;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;organelle assembly#GO:0070925;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198 protein-containing complex#GO:0032991 GTPase-activating protein#PC00257 HUMAN|HGNC=13202|UniProtKB=Q9P2N4 Q9P2N4 ADAMTS9 PTHR13723:SF33 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 9 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=4703|UniProtKB=P06028 P06028 GYPB PTHR13813:SF2 GLYCOPHORIN GLYCOPHORIN-B intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=3336|UniProtKB=Q14246 Q14246 ADGRE1 PTHR12011:SF449 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=20521|UniProtKB=P60372 P60372 KRTAP10-4 PTHR23262:SF227 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-4-RELATED HUMAN|HGNC=15309|UniProtKB=Q8N146 Q8N146 OR8H3 PTHR48018:SF153 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8H3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=6722|UniProtKB=P50895 P50895 BCAM PTHR11973:SF17 CELL SURFACE GLYCOPROTEIN MUC18-RELATED BASAL CELL ADHESION MOLECULE immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=11007|UniProtKB=P11169 P11169 SLC2A3 PTHR23503:SF99 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 3 HUMAN|HGNC=14917|UniProtKB=Q9NYW1 Q9NYW1 TAS2R9 PTHR11394:SF29 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 9 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=29827|UniProtKB=O14950 O14950 MYL12B PTHR23049:SF58 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 12B actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=13028|UniProtKB=Q9UL36 Q9UL36 ZNF236 PTHR24396:SF21 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 236 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29183|UniProtKB=Q9UPU7 Q9UPU7 TBC1D2B PTHR22957:SF621 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 2B GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=29883|UniProtKB=Q8TDQ1 Q8TDQ1 CD300LF PTHR11860:SF100 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 1 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=20974|UniProtKB=Q9HAR2 Q9HAR2 ADGRL3 PTHR12011:SF60 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR L3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 head development#GO:0060322;cellular component biogenesis#GO:0044085;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;animal organ development#GO:0048513;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;brain development#GO:0007420;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;cell junction assembly#GO:0034329;central nervous system development#GO:0007417;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;synapse assembly#GO:0007416;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 synapse#GO:0045202;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;glutamatergic synapse#GO:0098978;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=20465|UniProtKB=Q8IY18 Q8IY18 SMC5 PTHR45916:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 HUMAN|HGNC=33720|UniProtKB=Q4G0U5 Q4G0U5 CFAP221 PTHR46500:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 221 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 221 structural protein#PC00211 HUMAN|HGNC=25596|UniProtKB=Q96AE7 Q96AE7 TTC17 PTHR16091:SF1 TTC17 PROTEIN TETRATRICOPEPTIDE REPEAT PROTEIN 17 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26330|UniProtKB=Q8N7U6 Q8N7U6 EFHB PTHR12086:SF12 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER B calmodulin-related#PC00061 HUMAN|HGNC=22978|UniProtKB=O75164 O75164 KDM4A PTHR10694:SF119 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4A 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=7325|UniProtKB=P43246 P43246 MSH2 PTHR11361:SF35 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH2 nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;damaged DNA binding#GO:0003684;double-stranded DNA binding#GO:0003690;DNA-dependent ATPase activity#GO:0008094;mismatched DNA binding#GO:0030983;pyrophosphatase activity#GO:0016462;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;four-way junction DNA binding#GO:0000400;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;mismatch repair#GO:0006298;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;negative regulation of DNA recombination#GO:0045910;negative regulation of DNA metabolic process#GO:0051053;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=18890|UniProtKB=Q9BYR6 Q9BYR6 KRTAP3-3 PTHR23260:SF1 KERATIN ASSOCIATED PROTEIN 3-3-RELATED KERATIN-ASSOCIATED PROTEIN 3-3 HUMAN|HGNC=27287|UniProtKB=Q8IUY3 Q8IUY3 GRAMD2A PTHR46973:SF1 GRAM DOMAIN-CONTAINING PROTEIN 2A GRAM DOMAIN-CONTAINING PROTEIN 2A phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 cellular localization#GO:0051641;metal ion transport#GO:0030001;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;regulation of metal ion transport#GO:0010959;ion transport#GO:0006811;transport#GO:0006810;endomembrane system organization#GO:0010256;regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;cellular component organization#GO:0016043;cation transport#GO:0006812;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;establishment of localization#GO:0051234;organelle organization#GO:0006996;biological regulation#GO:0065007;divalent inorganic cation transport#GO:0072511;regulation of ion transport#GO:0043269 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;extrinsic component of plasma membrane#GO:0019897;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;organelle membrane contact site#GO:0044232;membrane#GO:0016020;side of membrane#GO:0098552;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=11076|UniProtKB=Q15599 Q15599 SLC9A3R2 PTHR14191:SF4 PDZ DOMAIN CONTAINING PROTEIN NA(+)/H(+) EXCHANGE REGULATORY COFACTOR NHE-RF2 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 HUMAN|HGNC=34|UniProtKB=P78363 P78363 ABCA4 PTHR19229:SF190 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA RETINAL-SPECIFIC PHOSPHOLIPID-TRANSPORTING ATPASE ABCA4 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;phospholipid transporter activity#GO:0005548;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=29266|UniProtKB=Q9P2G3 Q9P2G3 KLHL14 PTHR45632:SF6 LD33804P KELCH-LIKE PROTEIN 14 HUMAN|HGNC=26977|UniProtKB=Q8N436 Q8N436 CPXM2 PTHR11532:SF45 PROTEASE M14 CARBOXYPEPTIDASE INACTIVE CARBOXYPEPTIDASE-LIKE PROTEIN X2 hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190 HUMAN|HGNC=7608|UniProtKB=B2RTY4 B2RTY4 MYO9A PTHR46184:SF3 UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN UNCONVENTIONAL MYOSIN-IXA Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=4114|UniProtKB=P22466 P22466 GAL PTHR16839:SF1 GALANIN GALANIN PEPTIDES HUMAN|HGNC=17107|UniProtKB=Q8NFU1 Q8NFU1 BEST2 PTHR10736:SF1 BESTROPHIN BESTROPHIN-2 ion channel#PC00133 HUMAN|HGNC=21653|UniProtKB=Q9NS56 Q9NS56 TOPORS PTHR46077:SF2 E3 UBIQUITIN-PROTEIN LIGASE TOPORS E3 UBIQUITIN-PROTEIN LIGASE TOPORS ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=14978|UniProtKB=Q9NRS6 Q9NRS6 SNX15 PTHR15508:SF9 RIBOSOMAL PROTEIN S6 KINASE SORTING NEXIN-15 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=34453|UniProtKB=A6NNL5 A6NNL5 C15orf61 PTHR34651:SF1 SIMILAR TO ENSANGP00000021391 SIMILAR TO ENSANGP00000021391 HUMAN|HGNC=14633|UniProtKB=P82987 P82987 ADAMTSL3 PTHR13723:SF169 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAMTS-LIKE PROTEIN 3 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=11069|UniProtKB=Q9UPR5 Q9UPR5 SLC8A2 PTHR11878:SF8 SODIUM/CALCIUM EXCHANGER SODIUM/CALCIUM EXCHANGER 2 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;cation:cation antiporter activity#GO:0015491;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;solute:cation antiporter activity#GO:0015298;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;sodium ion transport#GO:0006814;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725 synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;sarcolemma#GO:0042383;axon#GO:0030424;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=28724|UniProtKB=Q8IW19 Q8IW19 APLF PTHR21315:SF2 UNCHARACTERIZED APRATAXIN AND PNK-LIKE FACTOR catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9956|UniProtKB=Q01201 Q01201 RELB PTHR24169:SF18 NUCLEAR FACTOR NF-KAPPA-B PROTEIN TRANSCRIPTION FACTOR RELB cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to external biotic stimulus#GO:0043207;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;innate immune response#GO:0045087;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;inflammatory response#GO:0006954;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;NIK/NF-kappaB signaling#GO:0038061;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;Apoptosis signaling pathway#P00006>NFkappaB#P00297 HUMAN|HGNC=1333|UniProtKB=Q9NRY5 Q9NRY5 FAM114A2 PTHR12842:SF3 FI01459P PROTEIN FAM114A2 HUMAN|HGNC=29201|UniProtKB=Q9ULR0 Q9ULR0 ISY1 PTHR13021:SF8 PRE-MRNA-SPLICING FACTOR ISY1 PRE-MRNA-SPLICING FACTOR ISY1 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=8708|UniProtKB=Q9Y5G3 Q9Y5G3 PCDHGB1 PTHR24028:SF106 CADHERIN-87A PROTOCADHERIN GAMMA-B1 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=23836|UniProtKB=O15062 O15062 ZBTB5 PTHR24394:SF17 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9043|UniProtKB=Q9Y263 Q9Y263 PLAA PTHR19849:SF2 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN PHOSPHOLIPASE A-2-ACTIVATING PROTEIN protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;biological regulation#GO:0065007;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=6877|UniProtKB=P27361 P27361 MAPK3 PTHR24055:SF393 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 3 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>MAPK1/3#P07228;EGF receptor signaling pathway#P00018>ERK1-2#P00543;B cell activation#P00010>ERK#P00371;VEGF signaling pathway#P00056>MEK#P01402;Interleukin signaling pathway#P00036>ERK#P00965;PDGF signaling pathway#P00047>ERK#P01143;FGF signaling pathway#P00021>ERK1-2#P00627;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MAPK#P05937;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Toll receptor signaling pathway#P00054>ERK1#P01358;Angiogenesis#P00005>Erk#P00203;CCKR signaling map#P06959>MAPK3#P07119;VEGF signaling pathway#P00056>Erk#P01407;Apoptosis signaling pathway#P00006>MAPK#P00269;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;T cell activation#P00053>ERK#P01300;Angiogenesis#P00005>MEK#P00225;Integrin signalling pathway#P00034>ERK#P00907;Gonadotropin-releasing hormone receptor pathway#P06664>ERK1/2#P06786;Ras Pathway#P04393>ERK#P04542;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Parkinson disease#P00049>ERK#P01211;Endothelin signaling pathway#P00019>ERK#P00566 HUMAN|HGNC=51512|UniProtKB=A6NNV3 A6NNV3 SPDYE16 PTHR31156:SF26 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E1-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=12856|UniProtKB=P25490 P25490 YY1 PTHR14003:SF10 TRANSCRIPTIONAL REPRESSOR PROTEIN YY TRANSCRIPTIONAL REPRESSOR PROTEIN YY1 sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6353|UniProtKB=O95198 O95198 KLHL2 PTHR24412:SF155 KELCH PROTEIN KELCH-LIKE PROTEIN 2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26446|UniProtKB=Q6PI47 Q6PI47 KCTD18 PTHR14499:SF4 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD18 scaffold/adaptor protein#PC00226 HUMAN|HGNC=12710|UniProtKB=Q9UKI3 Q9UKI3 VPREB3 PTHR23267:SF133 IMMUNOGLOBULIN LIGHT CHAIN PRE-B LYMPHOCYTE PROTEIN 3 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=28451|UniProtKB=Q6UXF1 Q6UXF1 TMEM108 PTHR28673:SF1 TRANSMEMBRANE PROTEIN 108 TRANSMEMBRANE PROTEIN 108 cellular localization#GO:0051641;neurogenesis#GO:0022008;cell projection organization#GO:0030030;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;growth#GO:0040007;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axo-dendritic transport#GO:0008088;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular developmental process#GO:0048869;developmental cell growth#GO:0048588;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell growth#GO:0016049;cellular process#GO:0009987;transport along microtubule#GO:0010970;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;neuron projection development#GO:0031175;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;movement of cell or subcellular component#GO:0006928;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;generation of neurons#GO:0048699 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;endosome#GO:0005768;postsynaptic density#GO:0014069;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular#GO:0005622;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;postsynaptic specialization#GO:0099572;intracellular vesicle#GO:0097708;early endosome#GO:0005769;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;axon#GO:0030424;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=25677|UniProtKB=Q63HK3 Q63HK3 ZKSCAN2 PTHR23226:SF164 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9582|UniProtKB=P25105 P25105 PTAFR PTHR24233:SF6 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PLATELET-ACTIVATING FACTOR RECEPTOR nucleotide binding#GO:0000166;signaling receptor activity#GO:0038023;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=5181|UniProtKB=P04196 P04196 HRG PTHR13814:SF3 FETUIN HISTIDINE-RICH GLYCOPROTEIN carbohydrate derivative binding#GO:0097367;serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;glycosaminoglycan binding#GO:0005539;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;cation binding#GO:0043169;hydrolase activity#GO:0016787;heparin binding#GO:0008201;serine-type endopeptidase inhibitor activity#GO:0004867;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;molecular function regulator#GO:0098772;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;peptidase regulator activity#GO:0061134;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of coagulation#GO:0050818;nitrogen compound transport#GO:0071705;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of wound healing#GO:0061041;establishment of localization#GO:0051234;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;iron ion transport#GO:0006826;regulation of hydrolase activity#GO:0051336;transition metal ion transport#GO:0000041;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;negative regulation of coagulation#GO:0050819;macromolecule metabolic process#GO:0043170;positive regulation of response to external stimulus#GO:0032103;negative regulation of endopeptidase activity#GO:0010951;regulation of body fluid levels#GO:0050878;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;platelet activation#GO:0030168;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;wound healing#GO:0042060;cation transport#GO:0006812;regulation of catalytic activity#GO:0050790;organic substance transport#GO:0071702;positive regulation of response to stimulus#GO:0048584;negative regulation of multicellular organismal process#GO:0051241;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;positive regulation of wound healing#GO:0090303;metal ion transport#GO:0030001;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of peptidase activity#GO:0010466;ion transport#GO:0006811;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;hemostasis#GO:0007599;coagulation#GO:0050817;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;regulation of response to wounding#GO:1903034;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of blood coagulation#GO:0030195;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;blood coagulation#GO:0007596;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;vacuole#GO:0005773;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 protease inhibitor#PC00191 HUMAN|HGNC=13060|UniProtKB=Q14586 Q14586 ZNF267 PTHR24376:SF88 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 267 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=27780|UniProtKB=E2RYF7 E2RYF7 HCG22 PTHR22467:SF1 UNCHARACTERIZED PROTEIN PBMUCL2 HUMAN|HGNC=23075|UniProtKB=Q9H4B0 Q9H4B0 OSGEPL1 PTHR11735:SF6 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL-RELATED protein-containing complex#GO:0032991;EKC/KEOPS complex#GO:0000408;intracellular#GO:0005622 RNA processing factor#PC00147 HUMAN|HGNC=21923|UniProtKB=Q687X5 Q687X5 STEAP4 PTHR14239:SF5 DUDULIN-RELATED METALLOREDUCTASE STEAP4 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;iron ion transmembrane transport#GO:0034755;localization#GO:0051179;establishment of localization#GO:0051234;oxidation-reduction process#GO:0055114;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;metabolic process#GO:0008152 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=21964|UniProtKB=Q96M69 Q96M69 LRGUK PTHR23117:SF18 GUANYLATE KINASE-RELATED LEUCINE-RICH REPEAT AND GUANYLATE KINASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 kinase#PC00137 HUMAN|HGNC=5895|UniProtKB=P01709 P01709 IGLV2-8 PTHR23267:SF437 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 2-8 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|Gene=P12LL_HUMAN|UniProtKB=A6NNC1 A6NNC1 - PTHR15566:SF5 POM121-LIKE POM121-LIKE PROTEIN 1-LIKE-RELATED HUMAN|HGNC=24211|UniProtKB=Q5GAN4 Q5GAN4 RNASE12 PTHR11437:SF20 RIBONUCLEASE INACTIVE RIBONUCLEASE-LIKE PROTEIN 12-RELATED HUMAN|HGNC=17961|UniProtKB=Q7Z2W7 Q7Z2W7 TRPM8 PTHR13800:SF9 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 8 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;localization#GO:0051179;divalent metal ion transport#GO:0070838;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=3068|UniProtKB=Q05923 Q05923 DUSP2 PTHR10159:SF109 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 2 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;phosphoprotein phosphatase activity#GO:0004721;kinase activity#GO:0016301;kinase binding#GO:0019900;phosphoric ester hydrolase activity#GO:0042578;protein kinase activity#GO:0004672;transferase activity#GO:0016740;MAP kinase activity#GO:0004707;hydrolase activity#GO:0016787;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;ectoderm formation#GO:0001705;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;mesoderm morphogenesis#GO:0048332;intracellular signal transduction#GO:0035556;regulation of MAP kinase activity#GO:0043405;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;ectoderm development#GO:0007398;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;embryo development#GO:0009790;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;mesoderm formation#GO:0001707;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;endoderm formation#GO:0001706;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of MAP kinase activity#GO:0043407;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;mesoderm development#GO:0007498;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;formation of primary germ layer#GO:0001704;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;tissue morphogenesis#GO:0048729;embryonic morphogenesis#GO:0048598;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=7759|UniProtKB=Q9Y3R4 Q9Y3R4 NEU2 PTHR10628:SF6 SIALIDASE SIALIDASE-2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carbohydrate metabolic process#GO:0005975;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 hydrolase#PC00121 HUMAN|HGNC=13104|UniProtKB=Q9Y5A6 Q9Y5A6 ZSCAN21 PTHR23226:SF10 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 21 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4113|UniProtKB=O14976 O14976 GAK PTHR23172:SF34 AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED CYCLIN-G-ASSOCIATED KINASE protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 protein-containing complex disassembly#GO:0032984;cellular protein complex disassembly#GO:0043624;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 HUMAN|HGNC=23686|UniProtKB=Q5QP82 Q5QP82 DCAF10 PTHR14588:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 10 DDB1- AND CUL4-ASSOCIATED FACTOR 10 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 HUMAN|HGNC=17874|UniProtKB=P62310 P62310 LSM3 PTHR13110:SF15 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;cytoplasmic mRNA processing body assembly#GO:0033962;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398 supramolecular complex#GO:0099080;catalytic step 2 spliceosome#GO:0071013;U6 snRNP#GO:0005688;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;U5 snRNP#GO:0005682;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;ribonucleoprotein granule#GO:0035770;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=9985|UniProtKB=Q33E94 Q33E94 RFX4 PTHR12619:SF31 RFX TRANSCRIPTION FACTOR FAMILY TRANSCRIPTION FACTOR RFX4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=329|UniProtKB=O00468 O00468 AGRN PTHR10574:SF423 NETRIN/LAMININ-RELATED AGRIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;dendrite development#GO:0016358;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;motor neuron axon guidance#GO:0008045;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 HUMAN|HGNC=29059|UniProtKB=Q5JU85 Q5JU85 IQSEC2 PTHR10663:SF314 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 2 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=28050|UniProtKB=Q6FI81 Q6FI81 CIAPIN1 PTHR13273:SF17 ANAMORSIN ANAMORSIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=20187|UniProtKB=Q96BY7 Q96BY7 ATG2B PTHR13190:SF20 AUTOPHAGY-RELATED 2, ISOFORM A AUTOPHAGY-RELATED PROTEIN 2 HOMOLOG B phosphatidylinositol-3-phosphate binding#GO:0032266;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;macroautophagy#GO:0016236;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;autophagy of mitochondrion#GO:0000422;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;lysosomal microautophagy#GO:0016237;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;autophagy#GO:0006914;autophagy of nucleus#GO:0044804;piecemeal microautophagy of the nucleus#GO:0034727 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020;intracellular#GO:0005622;extrinsic component of membrane#GO:0019898 HUMAN|HGNC=18653|UniProtKB=Q8WZ60 Q8WZ60 KLHL6 PTHR24412:SF428 KELCH PROTEIN KELCH-LIKE PROTEIN 6 scaffold/adaptor protein#PC00226 HUMAN|HGNC=19834|UniProtKB=Q4W4Y0 Q4W4Y0 C14orf28 PTHR35350:SF1 HYPOTHETICAL LOC314168 HYPOTHETICAL LOC314168 HUMAN|HGNC=13610|UniProtKB=Q8NHM5 Q8NHM5 KDM2B PTHR23123:SF10 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 2B molecular function regulator#GO:0098772;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;demethylation#GO:0070988;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein demethylation#GO:0006482;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=18826|UniProtKB=Q9BQG2 Q9BQG2 NUDT12 PTHR42904:SF6 NUDIX HYDROLASE, NUDC SUBFAMILY PEROXISOMAL NADH PYROPHOSPHATASE NUDT12 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;nucleotide diphosphatase activity#GO:0004551 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;NADP metabolic process#GO:0006739;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 HUMAN|HGNC=16823|UniProtKB=P17152 P17152 TMEM11 PTHR15099:SF2 PROTEIN PM1 TRANSMEMBRANE PROTEIN 11, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=9105|UniProtKB=Q9ULL4 Q9ULL4 PLXNB3 PTHR22625:SF33 PLEXIN PLEXIN-B3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;negative regulation of cell motility#GO:2000146;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;negative regulation of cell migration#GO:0030336;positive regulation of axonogenesis#GO:0050772;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;regulation of GTPase activity#GO:0043087;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of neuron differentiation#GO:0045664;negative regulation of cell adhesion#GO:0007162;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;positive regulation of neuron projection development#GO:0010976;locomotion#GO:0040011;taxis#GO:0042330;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of cell projection organization#GO:0031346;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;biological adhesion#GO:0022610;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of cell adhesion#GO:0030155;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;positive regulation of neuron differentiation#GO:0045666;cellular response to stimulus#GO:0051716;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;cell migration#GO:0016477 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=14972|UniProtKB=Q9Y5X2 Q9Y5X2 SNX8 PTHR46571:SF1 SORTING NEXIN-8 SORTING NEXIN-8 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28740|UniProtKB=Q8IXQ8 Q8IXQ8 PDZD9 PTHR22698:SF1 PDZ DOMAIN-CONTAINING PROTEIN 9 PDZ DOMAIN-CONTAINING PROTEIN 9 HUMAN|HGNC=14846|UniProtKB=Q8NGP6 Q8NGP6 OR5M8 PTHR48018:SF83 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5M8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=4605|UniProtKB=P07492 P07492 GRP PTHR16866:SF2 GASTRIN-RELEASING PEPTIDE GASTRIN-RELEASING PEPTIDE neuropeptide hormone activity#GO:0005184;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=19199|UniProtKB=Q6W0C5 Q6W0C5 DPPA3 PTHR31577:SF2 DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 3-RELATED DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED PROTEIN 3 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;developmental process#GO:0032502;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;negative regulation of DNA metabolic process#GO:0051053;demethylation#GO:0070988;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;embryo development#GO:0009790;macromolecule methylation#GO:0043414;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26171|UniProtKB=Q0VG06 Q0VG06 FAAP100 PTHR14890:SF1 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 100 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 100 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=30623|UniProtKB=Q8WWL2 Q8WWL2 SPIRE2 PTHR21345:SF5 SPIRE PROTEIN SPIRE HOMOLOG 2 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;positive regulation of supramolecular fiber organization#GO:1902905;membrane organization#GO:0061024;nuclear division#GO:0000280;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;cytokinetic process#GO:0032506;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;cytoskeleton-dependent cytokinesis#GO:0061640;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;multi-organism reproductive process#GO:0044703;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;multicellular organismal reproductive process#GO:0048609;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;gamete generation#GO:0007276;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;cell division#GO:0051301;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;cellular process involved in reproduction in multicellular organism#GO:0022412;transport#GO:0006810;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;actin filament polymerization#GO:0030041;regulation of protein-containing complex assembly#GO:0043254;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;cytokinesis#GO:0000910;spindle localization#GO:0051653;regulation of anatomical structure size#GO:0090066;membrane fission#GO:0090148;multicellular organism reproduction#GO:0032504;regulation of actin filament length#GO:0030832;actin filament bundle assembly#GO:0051017;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;multi-organism process#GO:0051704;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;establishment of spindle localization#GO:0051293;positive regulation of protein-containing complex assembly#GO:0031334;regulation of cellular component size#GO:0032535;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;microtubule-based process#GO:0007017;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;cell cortex#GO:0005938;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=13621|UniProtKB=Q9H2J7 Q9H2J7 SLC6A15 PTHR11616:SF101 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT2 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;amino acid:sodium symporter activity#GO:0005283;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 leucine transport#GO:0015820;neutral amino acid transport#GO:0015804;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;branched-chain amino acid transport#GO:0015803;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;anion transport#GO:0006820;sodium ion transmembrane transport#GO:0035725 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 HUMAN|HGNC=6215|UniProtKB=Q15046 Q15046 KARS1 PTHR42918:SF9 LYSYL-TRNA SYNTHETASE LYSINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;tRNA binding#GO:0000049;ligase activity#GO:0016874;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a tRNA#GO:0140101;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=29097|UniProtKB=Q66K14 Q66K14 TBC1D9B PTHR22957:SF225 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 9B GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=2316|UniProtKB=O75131 O75131 CPNE3 PTHR10857:SF22 COPINE COPINE-3 calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;lipid binding#GO:0008289;ion binding#GO:0043167;protein tyrosine kinase binding#GO:1990782;anion binding#GO:0043168;phospholipid binding#GO:0005543;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;enzyme linked receptor protein signaling pathway#GO:0007167;response to metal ion#GO:0010038;cell communication#GO:0007154;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=32204|UniProtKB=P0CG33 P0CG33 GOLGA6D PTHR10881:SF44 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 6A-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=28046|UniProtKB=Q9UDW3 Q9UDW3 ZMAT5 PTHR16465:SF1 NUCLEASE-RELATED ZINC FINGER MATRIN-TYPE PROTEIN 5 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U12-type spliceosomal complex#GO:0005689 HUMAN|HGNC=29427|UniProtKB=Q8TF17 Q8TF17 SH3TC2 PTHR22647:SF2 SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2 HUMAN|HGNC=6609|UniProtKB=O75023 O75023 LILRB5 PTHR11738:SF108 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 5 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=15431|UniProtKB=Q9NZP5 Q9NZP5 OR5AC2 PTHR26452:SF818 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AC2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=25532|UniProtKB=Q9NVV4 Q9NVV4 MTPAP PTHR12271:SF33 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE, MITOCHONDRIAL adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 HUMAN|HGNC=28363|UniProtKB=Q9H7T9 Q9H7T9 AUNIP PTHR14526:SF2 AURORA KINASE A AND NINEIN-INTERACTING PROTEIN AURORA KINASE A AND NINEIN-INTERACTING PROTEIN cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;spindle organization#GO:0007051;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819;centrosome#GO:0005813 HUMAN|HGNC=30447|UniProtKB=Q8N2A8 Q8N2A8 PLD6 PTHR43856:SF1 CARDIOLIPIN HYDROLASE MITOCHONDRIAL CARDIOLIPIN HYDROLASE cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;RNA metabolic process#GO:0016070;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 phospholipase#PC00186 HUMAN|HGNC=4530|UniProtKB=P48146 P48146 NPBWR2 PTHR24229:SF18 NEUROPEPTIDES RECEPTOR NEUROPEPTIDES B/W RECEPTOR TYPE 2 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=28398|UniProtKB=Q5T1N1 Q5T1N1 AKNAD1 PTHR21510:SF16 FAMILY NOT NAMED PROTEIN AKNAD1 HUMAN|HGNC=15827|UniProtKB=Q9UKG4 Q9UKG4 SLC13A4 PTHR10283:SF63 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 4 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=25021|UniProtKB=Q2TB18 Q2TB18 ASTE1 PTHR15665:SF1 ASTEROID PROTEIN PROTEIN ASTEROID HOMOLOG 1 HUMAN|HGNC=18108|UniProtKB=P59861 P59861 DEFB131A PTHR47900:SF1 BETA-DEFENSIN 131A BETA-DEFENSIN 131A extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=28319|UniProtKB=Q96S96 Q96S96 PEBP4 PTHR11362:SF70 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 EGF receptor signaling pathway#P00018>RKIP#P00548;FGF signaling pathway#P00021>RKIP#P00630 HUMAN|HGNC=21073|UniProtKB=Q8NBS9 Q8NBS9 TXNDC5 PTHR45672:SF3 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5 chaperone#PC00072 HUMAN|HGNC=24704|UniProtKB=Q659C4 Q659C4 LARP1B PTHR22792:SF50 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 1B RNA metabolism protein#PC00031 HUMAN|HGNC=12836|UniProtKB=Q9H0D6 Q9H0D6 XRN2 PTHR12341:SF41 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;heterocyclic compound binding#GO:1901363;exonuclease activity#GO:0004527 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 exoribonuclease#PC00099 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 HUMAN|HGNC=29328|UniProtKB=Q6P280 Q6P280 ZNF529 PTHR24381:SF309 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 529 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=14275|UniProtKB=Q9BYD6 Q9BYD6 MRPL1 PTHR23105:SF110 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER 39S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=10803|UniProtKB=P35247 P35247 SFTPD PTHR24024:SF15 PULMONARY SURFACTANT-ASSOCIATED PROTEIN A PULMONARY SURFACTANT-ASSOCIATED PROTEIN D endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;extracellular space#GO:0005615;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;rough endoplasmic reticulum#GO:0005791;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum#GO:0005783;late endosome#GO:0005770;plasma membrane#GO:0005886 surfactant#PC00212 HUMAN|Gene=SRCRM_HUMAN|UniProtKB=Q4G0T1 Q4G0T1 - PTHR19331:SF458 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN SCART1 serine protease#PC00203 HUMAN|HGNC=30757|UniProtKB=Q9Y2K9 Q9Y2K9 STXBP5L PTHR10241:SF19 LETHAL 2 GIANT LARVAE PROTEIN SYNTAXIN-BINDING PROTEIN 5-LIKE GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;myosin binding#GO:0017022;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;syntaxin binding#GO:0019905;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;protein secretion#GO:0009306;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;amide transport#GO:0042886;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;regulation of protein transport#GO:0051223;regulation of protein localization#GO:0032880;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;regulation of protein secretion#GO:0050708;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular#GO:0005622;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=26142|UniProtKB=Q9H6X4 Q9H6X4 TMEM134 PTHR13558:SF1 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 134 HUMAN|HGNC=20412|UniProtKB=P35900 P35900 KRT20 PTHR23239:SF167 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 20 HUMAN|HGNC=13557|UniProtKB=Q9BYF1 Q9BYF1 ACE2 PTHR10514:SF24 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME 2 hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=29249|UniProtKB=Q6P3S6 Q6P3S6 FBXO42 PTHR46432:SF1 F-BOX ONLY PROTEIN 42 F-BOX ONLY PROTEIN 42 HUMAN|HGNC=26564|UniProtKB=Q5T1B0 Q5T1B0 AXDND1 PTHR23052:SF1 UNCHARACTERIZED AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=17189|UniProtKB=O95897 O95897 OLFM2 PTHR23192:SF27 OLFACTOMEDIN-RELATED NOELIN-2 structural protein#PC00211 HUMAN|HGNC=19061|UniProtKB=Q5NUL3 Q5NUL3 FFAR4 PTHR24241:SF67 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR FREE FATTY ACID RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=3703|UniProtKB=Q14192 Q14192 FHL2 PTHR24205:SF3 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 transcription cofactor#PC00217 HUMAN|HGNC=26716|UniProtKB=Q8N9Q2 Q8N9Q2 SREK1IP1 PTHR31437:SF1 SREK1IP1 FAMILY MEMBER PROTEIN SREK1IP1 HUMAN|HGNC=2096|UniProtKB=Q15846 Q15846 CLUL1 PTHR10970:SF2 CLUSTERIN CLUSTERIN-LIKE PROTEIN 1 HUMAN|HGNC=14536|UniProtKB=Q9UIH9 Q9UIH9 KLF15 PTHR23235:SF44 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 15 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=18921|UniProtKB=G5E9R7 G5E9R7 KRTAP4-16 PTHR23262:SF71 KERATIN ASSOCIATED PROTEIN HCG2042993-RELATED HUMAN|HGNC=28097|UniProtKB=Q96A19 Q96A19 CCDC102A PTHR46292:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 102A COILED-COIL DOMAIN-CONTAINING PROTEIN 102A HUMAN|HGNC=5409|UniProtKB=P09913 P09913 IFIT2 PTHR10271:SF4 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 2 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=12877|UniProtKB=O75844 O75844 ZMPSTE24 PTHR10120:SF24 CAAX PRENYL PROTEASE 1 CAAX PRENYL PROTEASE 1 HOMOLOG hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein processing#GO:0016485;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein prenylation#GO:0018342;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 metalloprotease#PC00153 HUMAN|HGNC=30186|UniProtKB=Q9UHW5 Q9UHW5 GPN3 PTHR21231:SF7 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 3 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 small GTPase#PC00208 HUMAN|HGNC=21862|UniProtKB=Q8WVS4 Q8WVS4 WDR60 PTHR12442:SF30 DYNEIN INTERMEDIATE CHAIN WD REPEAT-CONTAINING PROTEIN 60 dynein heavy chain binding#GO:0045504;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;transport along microtubule#GO:0010970 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=30386|UniProtKB=Q8TAC9 Q8TAC9 SCAMP5 PTHR10687:SF5 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 5 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;protein transport#GO:0015031;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 HUMAN|HGNC=28868|UniProtKB=O00425 O00425 IGF2BP3 PTHR10288:SF158 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 regulation of biological process#GO:0050789;system development#GO:0048731;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;anatomical structure development#GO:0048856;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological regulation#GO:0065007;gene expression#GO:0010467;multicellular organismal process#GO:0032501;regulation of gene expression#GO:0010468;nervous system development#GO:0007399;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=11540|UniProtKB=P49848 P49848 TAF6 PTHR10221:SF12 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;RNA polymerase II general transcription initiation factor activity#GO:0016251 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=24269|UniProtKB=Q9Y315 Q9Y315 DERA PTHR10889:SF3 DEOXYRIBOSE-PHOSPHATE ALDOLASE DEOXYRIBOSE-PHOSPHATE ALDOLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 aldolase#PC00044 HUMAN|HGNC=588|UniProtKB=O94817 O94817 ATG12 PTHR13385:SF5 AUTOPHAGY PROTEIN 12 UBIQUITIN-LIKE PROTEIN ATG12 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein lipidation#GO:0006497;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;C-terminal protein amino acid modification#GO:0018410;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;lipoprotein metabolic process#GO:0042157;autophagy#GO:0006914;autophagy of nucleus#GO:0044804 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;whole membrane#GO:0098805 HUMAN|HGNC=28666|UniProtKB=Q9BQ75 Q9BQ75 CMSS1 PTHR24030:SF0 PROTEIN CMSS1 PROTEIN CMSS1 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 HUMAN|HGNC=11915|UniProtKB=Q9NS68 Q9NS68 TNFRSF19 PTHR12120:SF1 TNFR-CYS DOMAIN-CONTAINING PROTEIN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=11179|UniProtKB=P00441 P00441 SOD1 PTHR10003:SF66 SUPEROXIDE DISMUTASE CU-ZN -RELATED SUPEROXIDE DISMUTASE [CU-ZN] cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stimulus#GO:0050896;cellular response to chemical stress#GO:0062197;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to toxic substance#GO:0009636;cellular response to stress#GO:0033554;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cytosol#GO:0005829;mitochondrion#GO:0005739;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176 HUMAN|HGNC=16127|UniProtKB=Q5JWF8 Q5JWF8 ACTL10 PTHR11937:SF183 ACTIN ACTIN-LIKE PROTEIN 10 actin and actin related protein#PC00039 HUMAN|HGNC=27139|UniProtKB=Q96DD7 Q96DD7 SHISA4 PTHR31395:SF5 SHISA PROTEIN SHISA-4 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3390|UniProtKB=Q15375 Q15375 EPHA7 PTHR24416:SF377 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-A RECEPTOR 7 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=4232|UniProtKB=P39905 P39905 GDNF PTHR12173:SF1 GDNF SUBFAMILY OF TGF-BETA FAMILY GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 neuron apoptotic process#GO:0051402;negative regulation of biological process#GO:0048519;regulation of neuron death#GO:1901214;regulation of anatomical structure morphogenesis#GO:0022603;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;kidney development#GO:0001822;peripheral nervous system development#GO:0007422;neuron death#GO:0070997;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;negative regulation of neuron death#GO:1901215;regulation of biological process#GO:0050789;urogenital system development#GO:0001655;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;cell death#GO:0008219;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;morphogenesis of a branching structure#GO:0001763;regulation of programmed cell death#GO:0043067;regulation of multicellular organismal process#GO:0051239;regulation of apoptotic process#GO:0042981;multicellular organism development#GO:0007275;tube development#GO:0035295;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;negative regulation of apoptotic process#GO:0043066;tissue development#GO:0009888;negative regulation of cell death#GO:0060548;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;tissue morphogenesis#GO:0048729;regulation of cell death#GO:0010941;morphogenesis of an epithelium#GO:0002009;multicellular organismal process#GO:0032501;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 neurotrophic factor#PC00163 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=23396|UniProtKB=Q5SRE7 Q5SRE7 PHYHD1 PTHR20883:SF15 PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1 oxygenase#PC00177 HUMAN|HGNC=9347|UniProtKB=Q13029 Q13029 PRDM2 PTHR16515:SF37 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26799|UniProtKB=Q8N8R5 Q8N8R5 C2orf69 PTHR31296:SF1 UPF0565 PROTEIN C2ORF69 UPF0565 PROTEIN C2ORF69 HUMAN|HGNC=33342|UniProtKB=Q6PDA7 Q6PDA7 SPAG11A PTHR14081:SF1 SPERM-ASSOCIATED ANTIGEN 11A-RELATED-RELATED SPERM-ASSOCIATED ANTIGEN 11A-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 HUMAN|HGNC=14873|UniProtKB=Q9P0K7 Q9P0K7 RAI14 PTHR24129:SF0 ANKYCORBIN ANKYCORBIN HUMAN|HGNC=12499|UniProtKB=Q14139 Q14139 UBE4A PTHR13931:SF16 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 A ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=25322|UniProtKB=Q8N999 Q8N999 C12orf29 PTHR31219:SF2 CHROMOSOME 28 C12ORF29 HOMOLOG CHROMOSOME 12 OPEN READING FRAME 29 HUMAN|HGNC=15676|UniProtKB=Q9BWG4 Q9BWG4 SSBP4 PTHR12610:SF30 SINGLE STRANDED DNA BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN 4 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 HUMAN|HGNC=15473|UniProtKB=Q96PN8 Q96PN8 TSSK3 PTHR24343:SF74 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE/THREONINE-PROTEIN KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=20335|UniProtKB=Q9UIL1 Q9UIL1 SCOC PTHR21614:SF1 SHORT COILED COIL PROTEIN SHORT COILED-COIL PROTEIN trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=11828|UniProtKB=Q9UDY2 Q9UDY2 TJP2 PTHR13865:SF26 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN ZO-2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 blood circulation#GO:0008015;cell-cell junction organization#GO:0045216;cellular developmental process#GO:0048869;macromolecule localization#GO:0033036;epithelium development#GO:0060429;system process#GO:0003008;developmental process#GO:0032502;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;homeostatic process#GO:0042592;cell adhesion#GO:0007155;cellular component organization#GO:0016043;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;circulatory system process#GO:0003013;tissue development#GO:0009888;protein localization#GO:0008104;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;multicellular organismal homeostasis#GO:0048871;tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446;anatomical structure homeostasis#GO:0060249 anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical junction complex#GO:0043296 tight junction#PC00214 HUMAN|HGNC=1152|UniProtKB=Q8NE79 Q8NE79 BVES PTHR12101:SF17 POPEYE DOMAIN CONTAINING PROTEIN BLOOD VESSEL EPICARDIAL SUBSTANCE nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;sarcolemma#GO:0042383 HUMAN|HGNC=24092|UniProtKB=Q9H213 Q9H213 MAGEH1 PTHR11736:SF8 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN H1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11719|UniProtKB=P42680 P42680 TEC PTHR24418:SF219 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE TEC protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;B cell receptor signaling pathway#GO:0050853;peptidyl-amino acid modification#GO:0018193;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;adaptive immune response#GO:0002250;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;peptidyl-tyrosine modification#GO:0018212;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852 HUMAN|HGNC=4585|UniProtKB=Q12879 Q12879 GRIN2A PTHR18966:SF407 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2A amino acid binding#GO:0016597;cation channel activity#GO:0005261;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;neurotransmitter receptor activity#GO:0030594;voltage-gated cation channel activity#GO:0022843;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;glutamate binding#GO:0016595;ligand-gated channel activity#GO:0022834 signal transduction#GO:0007165;chemical synaptic transmission, postsynaptic#GO:0099565;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;integral component of plasma membrane#GO:0005887;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Ionotropic glutamate receptor pathway#P00037>NR2B#P01007;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Ionotropic glutamate receptor pathway#P00037>NR2A#P01008;Ionotropic glutamate receptor pathway#P00037>NR2C#P01006 HUMAN|HGNC=23787|UniProtKB=Q9P1W3 Q9P1W3 TMEM63C PTHR13018:SF21 PROBABLE MEMBRANE PROTEIN DUF221-RELATED CALCIUM PERMEABLE STRESS-GATED CATION CHANNEL 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=11104|UniProtKB=Q92922 Q92922 SMARCC1 PTHR12802:SF9 SWI/SNF COMPLEX-RELATED SWI/SNF COMPLEX SUBUNIT SMARCC1 cis-regulatory region sequence-specific DNA binding#GO:0000987;nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;histone binding#GO:0042393;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=6052|UniProtKB=P20839 P20839 IMPDH1 PTHR11911:SF74 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 ribonucleoside triphosphate metabolic process#GO:0009199;cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine nucleoside triphosphate biosynthetic process#GO:0009145;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside triphosphate biosynthetic process#GO:0009142;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 HUMAN|HGNC=9327|UniProtKB=P01298 P01298 PPY PTHR10533:SF2 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PANCREATIC PROHORMONE neuropeptide hormone activity#GO:0005184;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;behavior#GO:0007610;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intercellular signal molecule#PC00207 HUMAN|HGNC=37246|UniProtKB=C9JN71 C9JN71 ZNF878 PTHR24379:SF109 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 878 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29830|UniProtKB=Q9H0A0 Q9H0A0 NAT10 PTHR10925:SF5 N-ACETYLTRANSFERASE 10 RNA CYTIDINE ACETYLTRANSFERASE transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;N-acyltransferase activity#GO:0016410 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA processing factor#PC00147 HUMAN|HGNC=20628|UniProtKB=Q9UI26 Q9UI26 IPO11 PTHR10997:SF7 IMPORTIN-7, 8, 11 IMPORTIN-11 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=4253|UniProtKB=Q4G0N0 Q4G0N0 GGTA1P PTHR10462:SF26 GLYCOSYLTRANSFERASE-RELATED INACTIVE N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=19092|UniProtKB=Q9BQI7 Q9BQI7 PSD2 PTHR10663:SF329 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 2 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=37169|UniProtKB=P0DMP1 P0DMP1 MTRNR2L12 PTHR33895:SF15 HUMANIN-LIKE 4 HUMANIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=9748|UniProtKB=P10082 P10082 PYY PTHR10533:SF14 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PEPTIDE YY-RELATED neuropeptide hormone activity#GO:0005184;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;behavior#GO:0007610;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intercellular signal molecule#PC00207 HUMAN|HGNC=23172|UniProtKB=Q8N699 Q8N699 MYCT1 PTHR14869:SF0 MYC TARGET PROTEIN 1 MYC TARGET PROTEIN 1 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17001|UniProtKB=P48060 P48060 GLIPR1 PTHR10334:SF459 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GLIOMA PATHOGENESIS-RELATED PROTEIN 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=23692|UniProtKB=P25106 P25106 ACKR3 PTHR10489:SF931 CELL ADHESION MOLECULE ATYPICAL CHEMOKINE RECEPTOR 3 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 HUMAN|HGNC=12507|UniProtKB=Q9NZI7 Q9NZI7 UBP1 PTHR11037:SF13 TRANSCRIPTION FACTOR CP2 UPSTREAM-BINDING PROTEIN 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=11582|UniProtKB=Q15813 Q15813 TBCE PTHR15140:SF31 TUBULIN-SPECIFIC CHAPERONE E TUBULIN-SPECIFIC CHAPERONE E cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein folding#GO:0006457;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=1983|UniProtKB=Q969X6 Q969X6 UTP4 PTHR44163:SF1 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 HUMAN|Gene=YM017_HUMAN|UniProtKB=A8MX80 A8MX80 - PTHR11639:SF71 S100 CALCIUM-BINDING PROTEIN UPF0607 PROTEIN ENSP00000332738-RELATED protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=29222|UniProtKB=Q9H582 Q9H582 ZNF644 PTHR24396:SF25 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 644 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20813|UniProtKB=Q9H4T2 Q9H4T2 ZSCAN16 PTHR23226:SF52 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 16 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20297|UniProtKB=Q96PX8 Q96PX8 SLITRK1 PTHR45773:SF7 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 1 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;generation of neurons#GO:0048699;cell part morphogenesis#GO:0032990 HUMAN|HGNC=11532|UniProtKB=Q15573 Q15573 TAF1A PTHR32122:SF1 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT A TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT A General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>SL1 complex#P00653 HUMAN|HGNC=21869|UniProtKB=Q53H12 Q53H12 AGK PTHR12358:SF86 SPHINGOSINE KINASE ACYLGLYCEROL KINASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;phosphate-containing compound metabolic process#GO:0006796;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 HUMAN|HGNC=22393|UniProtKB=Q76B58 Q76B58 BRINP3 PTHR15564:SF2 MACPF DOMAIN-CONTAINING PROTEIN BMP/RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3 HUMAN|HGNC=5101|UniProtKB=P31270 P31270 HOXA11 PTHR46092:SF3 HOMEOBOX PROTEIN HOX-A11-RELATED HOMEOBOX PROTEIN HOX-A11 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=29865|UniProtKB=Q9Y3E7 Q9Y3E7 CHMP3 PTHR10476:SF1 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 3 endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;peptide transport#GO:0015833;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=9900|UniProtKB=P98179 P98179 RBM3 PTHR48034:SF12 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA-BINDING PROTEIN 3 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;positive regulation of RNA metabolic process#GO:0051254;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=6067|UniProtKB=P09529 P09529 INHBB PTHR11848:SF29 TGF-BETA FAMILY INHIBIN BETA B CHAIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>Inhba/b#P06700 HUMAN|HGNC=14402|UniProtKB=Q9H2X6 Q9H2X6 HIPK2 PTHR24058:SF53 DUAL SPECIFICITY PROTEIN KINASE HOMEODOMAIN-INTERACTING PROTEIN KINASE 2 SMAD binding#GO:0046332;protein tyrosine kinase activity#GO:0004713;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;activating transcription factor binding#GO:0033613;transcription factor binding#GO:0008134;kinase activity#GO:0016301;protein kinase activity#GO:0004672;DNA-binding transcription factor binding#GO:0140297;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transferase activity#GO:0016740;transcription corepressor activity#GO:0003714;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;catalytic activity, acting on a protein#GO:0140096 positive regulation of gene expression#GO:0010628;smoothened signaling pathway#GO:0007224;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;positive regulation of transcription, DNA-templated#GO:0045893;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;programmed cell death#GO:0012501;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;signal transduction by p53 class mediator#GO:0072331;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;cell death#GO:0008219;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;peptidyl-threonine phosphorylation#GO:0018107;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229;PML body#GO:0016605 HUMAN|HGNC=2952|UniProtKB=Q96JB1 Q96JB1 DNAH8 PTHR10676:SF361 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN 8, AXONEMAL pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;outer dynein arm assembly#GO:0036158;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=16673|UniProtKB=Q9BTT0 Q9BTT0 ANP32E PTHR11375:SF5 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER E hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;phosphatase regulator activity#GO:0019208;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;histone binding#GO:0042393;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=38705|UniProtKB=P0CJ78 P0CJ78 ZNF865 PTHR24390:SF62 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 865 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=12928|UniProtKB=P52747 P52747 ZNF143 PTHR24388:SF55 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 143 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=120|UniProtKB=Q99424 Q99424 ACOX2 PTHR10909:SF344 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 2 nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;very long-chain fatty acid metabolic process#GO:0000038;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;regulation of biological quality#GO:0065008;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;cellular process#GO:0009987;chemical homeostasis#GO:0048878;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176 HUMAN|HGNC=5580|UniProtKB=P01762 P01762 IGHV3-11 PTHR23266:SF357 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-11-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=6356|UniProtKB=Q96PQ7 Q96PQ7 KLHL5 PTHR24412:SF135 KELCH PROTEIN KELCH-LIKE PROTEIN 5 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9065|UniProtKB=P19174 P19174 PLCG1 PTHR10336:SF173 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-1 regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;regulation of localization#GO:0032879;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular component movement#GO:0051272;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;positive regulation of cell migration#GO:0030335;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;cell migration#GO:0016477;locomotion#GO:0040011;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 phospholipase#PC00186 VEGF signaling pathway#P00056>PLC-gamma#P01414;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;FGF signaling pathway#P00021>PLCgamma#P00638;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Angiogenesis#P00005>PLC-gamma#P00256;EGF receptor signaling pathway#P00018>PLCgamma#P00556;PDGF signaling pathway#P00047>PLCgamma#P01171;T cell activation#P00053>PLC-gamma#P01320;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;CCKR signaling map#P06959>PLCgamma1#P07037 HUMAN|HGNC=5743|UniProtKB=A0A0C4DH67 A0A0C4DH67 IGKV1-8 PTHR23267:SF320 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-8-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=9232|UniProtKB=Q07869 Q07869 PPARA PTHR24082:SF197 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;negative regulation of inflammatory response#GO:0050728;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;regulation of defense response#GO:0031347;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of lipid metabolic process#GO:0019216;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;inflammatory response#GO:0006954;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of inflammatory response#GO:0050727;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>PPARalpha/gamma#P06744 HUMAN|HGNC=16893|UniProtKB=O60664 O60664 PLIN3 PTHR14024:SF11 PERILIPIN PERILIPIN-3 localization#GO:0051179;regulation of biological process#GO:0050789;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;maintenance of location#GO:0051235;biological regulation#GO:0065007;regulation of localization#GO:0032879;lipid localization#GO:0010876;lipid storage#GO:0019915;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;intracellular#GO:0005622;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29118|UniProtKB=O94886 O94886 TMEM63A PTHR13018:SF24 PROBABLE MEMBRANE PROTEIN DUF221-RELATED CSC1-LIKE PROTEIN 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=3444|UniProtKB=P50548 P50548 ERF PTHR11849:SF31 ETS ETS DOMAIN-CONTAINING TRANSCRIPTION FACTOR ERF sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=9208|UniProtKB=P16435 P16435 POR PTHR19384:SF17 NITRIC OXIDE SYNTHASE-RELATED NADPH--CYTOCHROME P450 REDUCTASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidoreductase#PC00176 Sulfate assimilation#P02778>Sulfite reductase#P03165;Vitamin D metabolism and pathway#P04396>P450 reductase#P04605 HUMAN|HGNC=20073|UniProtKB=Q96L92 Q96L92 SNX27 PTHR12431:SF19 SORTING NEXIN 17 AND 27 SORTING NEXIN-27 lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;retrograde transport, endosome to plasma membrane#GO:1990126;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25988|UniProtKB=Q9NXF1 Q9NXF1 TEX10 PTHR16056:SF2 UNCHARACTERIZED TESTIS-EXPRESSED PROTEIN 10 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=27648|UniProtKB=Q5T0L3 Q5T0L3 SPATA46 PTHR33517:SF4 PROTEIN FAM170B-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 46 male gamete generation#GO:0048232;plasma membrane fusion#GO:0045026;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;membrane organization#GO:0061024;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;cellular component organization#GO:0016043;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;membrane fusion#GO:0061025;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=10642|UniProtKB=P42830 P42830 CXCL5 PTHR10179:SF86 CXC CHEMOKINE C-X-C MOTIF CHEMOKINE 5 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;molecular function regulator#GO:0098772;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;humoral immune response#GO:0006959;cellular response to lipopolysaccharide#GO:0071222;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;cytokine-mediated signaling pathway#GO:0019221;response to molecule of bacterial origin#GO:0002237;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;signaling#GO:0023052;chemotaxis#GO:0006935;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;neutrophil migration#GO:1990266;cellular response to biotic stimulus#GO:0071216;localization of cell#GO:0051674;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;response to lipopolysaccharide#GO:0032496;cell chemotaxis#GO:0060326;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;antimicrobial humoral response#GO:0019730;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011;taxis#GO:0042330 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=18672|UniProtKB=Q96SN8 Q96SN8 CDK5RAP2 PTHR46930:SF1 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;tubulin binding#GO:0015631;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;enzyme binding#GO:0019899;microtubule binding#GO:0008017;double-stranded DNA binding#GO:0003690;calmodulin binding#GO:0005516;kinase binding#GO:0019900;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;protein kinase binding#GO:0019901 positive regulation of gene expression#GO:0010628;negative regulation of sister chromatid segregation#GO:0033046;cellular component biogenesis#GO:0044085;organelle localization#GO:0051640;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;centrosome cycle#GO:0007098;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;regulation of cellular component biogenesis#GO:0044087;regulation of mitotic sister chromatid segregation#GO:0033047;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;regulation of centrosome duplication#GO:0010824;protein-containing complex subunit organization#GO:0043933;cellular protein-containing complex assembly#GO:0034622;mitotic sister chromatid separation#GO:0051306;chromosome separation#GO:0051304;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;cellular aromatic compound metabolic process#GO:0006725;regulation of microtubule-based process#GO:0032886;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;positive regulation of RNA biosynthetic process#GO:1902680;mitotic cell cycle phase transition#GO:0044772;RNA metabolic process#GO:0016070;regulation of chromosome separation#GO:1905818;cellular macromolecule metabolic process#GO:0044260;establishment of spindle orientation#GO:0051294;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;biosynthetic process#GO:0009058;negative regulation of cell cycle process#GO:0010948;negative regulation of mitotic cell cycle phase transition#GO:1901991;positive regulation of biosynthetic process#GO:0009891;regulation of protein-containing complex assembly#GO:0043254;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;supramolecular fiber organization#GO:0097435;positive regulation of macromolecule biosynthetic process#GO:0010557;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;spindle localization#GO:0051653;regulation of chromosome organization#GO:0033044;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;regulation of mitotic sister chromatid separation#GO:0010965;mitotic cell cycle checkpoint#GO:0007093;regulation of nuclear division#GO:0051783;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of protein-containing complex assembly#GO:0031334;regulation of supramolecular fiber organization#GO:1902903;establishment of mitotic spindle localization#GO:0040001;regulation of nucleobase-containing compound metabolic process#GO:0019219;microtubule bundle formation#GO:0001578;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of mitotic cell cycle#GO:0007346;cellular localization#GO:0051641;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;positive regulation of supramolecular fiber organization#GO:1902905;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;microtubule polymerization or depolymerization#GO:0031109;establishment of cell polarity#GO:0030010;transcription, DNA-templated#GO:0006351;establishment of localization#GO:0051234;microtubule polymerization#GO:0046785;nitrogen compound metabolic process#GO:0006807;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;RNA biosynthetic process#GO:0032774;microtubule organizing center organization#GO:0031023;positive regulation of cellular process#GO:0048522;establishment of mitotic spindle orientation#GO:0000132;aromatic compound biosynthetic process#GO:0019438;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of mitotic sister chromatid separation#GO:2000816;establishment or maintenance of cell polarity#GO:0007163;positive regulation of organelle organization#GO:0010638;protein-containing complex assembly#GO:0065003;centrosome duplication#GO:0051298;mitotic cell cycle process#GO:1903047;regulation of transcription, DNA-templated#GO:0006355;cell cycle checkpoint#GO:0000075;positive regulation of metabolic process#GO:0009893;regulation of microtubule cytoskeleton organization#GO:0070507;mitotic spindle assembly checkpoint#GO:0007094;positive regulation of cellular component biogenesis#GO:0044089;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;cellular biosynthetic process#GO:0044249;negative regulation of mitotic cell cycle#GO:0045930;organic substance biosynthetic process#GO:1901576;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of RNA metabolic process#GO:0051252;establishment of spindle localization#GO:0051293;positive regulation of protein polymerization#GO:0032273;centriole replication#GO:0007099;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;metaphase/anaphase transition of cell cycle#GO:0044784;nucleic acid metabolic process#GO:0090304;negative regulation of chromosome separation#GO:1905819;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;microtubule-based process#GO:0007017;organelle organization#GO:0006996;biological regulation#GO:0065007;protein polymerization#GO:0051258;organelle fission#GO:0048285;positive regulation of cytoskeleton organization#GO:0051495;establishment of localization in cell#GO:0051649;regulation of cellular macromolecule biosynthetic process#GO:2000112 supramolecular complex#GO:0099080;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;perinuclear region of cytoplasm#GO:0048471;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;centriole#GO:0005814;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;gamma-tubulin complex#GO:0000930;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 HUMAN|HGNC=19315|UniProtKB=Q96KP6 Q96KP6 TNIP3 PTHR31882:SF2 TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER TNFAIP3-INTERACTING PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 HUMAN|HGNC=26784|UniProtKB=Q9H3J6 Q9H3J6 C12orf65 PTHR46203:SF1 PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65 PEPTIDE CHAIN RELEASE FACTOR C12ORF65, MITOCHONDRIAL-RELATED translation release factor#PC00225 HUMAN|HGNC=20126|UniProtKB=Q96F83 Q96F83 CLBA1 PTHR16156:SF7 AFTIPHILIN A-RELATED CLATHRIN_BDG DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network transport vesicle#GO:0030140;trans-Golgi network#GO:0005802;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=20340|UniProtKB=Q7Z3G6 Q7Z3G6 PRICKLE2 PTHR24211:SF18 LIM DOMAIN-CONTAINING PROTEIN PRICKLE-LIKE PROTEIN 2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=4587|UniProtKB=Q14957 Q14957 GRIN2C PTHR18966:SF361 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2C amino acid binding#GO:0016597;cation channel activity#GO:0005261;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;neurotransmitter receptor activity#GO:0030594;voltage-gated cation channel activity#GO:0022843;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;glutamate binding#GO:0016595;ligand-gated channel activity#GO:0022834 signal transduction#GO:0007165;chemical synaptic transmission, postsynaptic#GO:0099565;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;integral component of plasma membrane#GO:0005887;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Ionotropic glutamate receptor pathway#P00037>NR2C#P01006;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 HUMAN|HGNC=7108|UniProtKB=Q9NPJ1 Q9NPJ1 MKKS PTHR46787:SF1 SYNDROMES PUTATIVE CHAPERONIN-RELATED SYNDROMES PUTATIVE CHAPERONIN-RELATED vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;intracellular organelle#GO:0043229;stereocilium#GO:0032420;non-membrane-bounded organelle#GO:0043228;stereocilium bundle#GO:0032421;kinocilium#GO:0060091;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;cluster of actin-based cell projections#GO:0098862;nucleus#GO:0005634;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;neuron projection#GO:0043005;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=8096|UniProtKB=O95190 O95190 OAZ2 PTHR10279:SF6 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME 2 carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;ornithine decarboxylase activity#GO:0004586;catalytic activity#GO:0003824;lyase activity#GO:0016829;molecular function regulator#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234 positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule catabolic process#GO:0009057;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;positive regulation of protein catabolic process#GO:0045732;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=16176|UniProtKB=Q9H171 Q9H171 ZBP1 PTHR14966:SF0 Z-DNA-BINDING PROTEIN 1 Z-DNA-BINDING PROTEIN 1 DNA metabolism protein#PC00009 HUMAN|HGNC=20087|UniProtKB=Q8TAM2 Q8TAM2 TTC8 PTHR44177:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 8 TETRATRICOPEPTIDE REPEAT PROTEIN 8 vesicle targeting, to, from or within Golgi#GO:0048199;non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;BBSome#GO:0034464;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=5128|UniProtKB=P09630 P09630 HOXC6 PTHR45659:SF1 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-C6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=18996|UniProtKB=Q8IV63 Q8IV63 VRK3 PTHR11909:SF99 CASEIN KINASE-RELATED INACTIVE SERINE/THREONINE-PROTEIN KINASE VRK3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;transport#GO:0006810;positive regulation of proteasomal protein catabolic process#GO:1901800;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of protein catabolic process#GO:0042176;positive regulation of Wnt signaling pathway#GO:0030177;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;vesicle organization#GO:0016050;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;canonical Wnt signaling pathway#GO:0060070;regulation of cellular protein catabolic process#GO:1903362;signaling#GO:0023052;cell-cell signaling#GO:0007267;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;Wnt signaling pathway#GO:0016055;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;vesicle budding from membrane#GO:0006900;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=16993|UniProtKB=P60468 P60468 SEC61B PTHR13509:SF3 SEC61 SUBUNIT BETA PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA membrane traffic protein#PC00150 HUMAN|HGNC=25166|UniProtKB=Q96E16 Q96E16 SMIM19 PTHR31888:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 19 SMALL INTEGRAL MEMBRANE PROTEIN 19 HUMAN|HGNC=9522|UniProtKB=Q15238 Q15238 PSG5 PTHR44337:SF15 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 11-RELATED HUMAN|HGNC=18527|UniProtKB=Q2M2I5 Q2M2I5 KRT24 PTHR23239:SF207 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 24 HUMAN|HGNC=1369|UniProtKB=Q9NS85 Q9NS85 CA10 PTHR18952:SF91 CARBONIC ANHYDRASE CARBONIC ANHYDRASE-RELATED PROTEIN 10 HUMAN|HGNC=597|UniProtKB=P51693 P51693 APLP1 PTHR23103:SF13 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID-LIKE PROTEIN 1 protease inhibitor#PC00191 HUMAN|HGNC=13285|UniProtKB=Q5HY92 Q5HY92 FIGN PTHR23074:SF14 AAA DOMAIN-CONTAINING FIDGETIN pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;ATPase activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=14966|UniProtKB=Q92626 Q92626 PXDN PTHR11475:SF75 OXIDASE/PEROXIDASE PEROXIDASIN HOMOLOG oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peroxidase#PC00180 HUMAN|HGNC=25246|UniProtKB=Q9H0I2 Q9H0I2 ENKD1 PTHR21490:SF2 UNCHARACTERIZED ENKURIN DOMAIN-CONTAINING PROTEIN 1 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 HUMAN|HGNC=21752|UniProtKB=Q9NRP4 Q9NRP4 SDHAF3 PTHR13137:SF6 DC11 ACN9 HOMOLOG SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 3, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;protein-containing complex assembly#GO:0065003;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular component organization or biogenesis#GO:0071840;mitochondrial respiratory chain complex II assembly#GO:0034553;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;protein-containing complex subunit organization#GO:0043933 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 HUMAN|HGNC=11646|UniProtKB=Q9UL49 Q9UL49 TCFL5 PTHR15402:SF2 TRANSCRIPTION FACTOR-LIKE 5 PROTEIN TRANSCRIPTION FACTOR-LIKE 5 PROTEIN heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;male gamete generation#GO:0048232;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;spermatogenesis#GO:0007283;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;gamete generation#GO:0007276;macromolecule biosynthetic process#GO:0009059;multicellular organism reproduction#GO:0032504;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;multi-organism process#GO:0051704;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;reproduction#GO:0000003;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=19237|UniProtKB=Q9NR45 Q9NR45 NANS PTHR42966:SF1 N-ACETYLNEURAMINATE SYNTHASE SIALIC ACID SYNTHASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 acetyltransferase#PC00038 HUMAN|HGNC=32305|UniProtKB=Q5VU69 Q5VU69 C1orf189 PTHR35818:SF1 C1ORF189 RGD1564171 HUMAN|HGNC=20573|UniProtKB=Q96QZ0 Q96QZ0 PANX3 PTHR15759:SF3 PANNEXIN PANNEXIN-3 HUMAN|HGNC=17310|UniProtKB=O60830 O60830 TIMM17B PTHR10485:SF2 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-B protein transmembrane transporter activity#GO:0008320;amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 transporter#PC00227 HUMAN|HGNC=30932|UniProtKB=Q6GPH4 Q6GPH4 XAF1 PTHR16295:SF17 TRAF-TYPE ZINC FINGER PROTEIN-RELATED XIAP-ASSOCIATED FACTOR 1 cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14568|UniProtKB=Q9BYT3 Q9BYT3 STK33 PTHR44167:SF6 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED SERINE/THREONINE-PROTEIN KINASE 33 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;nuclear division#GO:0000280;cell cycle process#GO:0022402;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;cell cycle checkpoint#GO:0000075;signal transduction in response to DNA damage#GO:0042770;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle#GO:0045786;mitotic DNA damage checkpoint#GO:0044773;cellular component organization#GO:0016043;negative regulation of mitotic cell cycle#GO:0045930;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;mitotic DNA integrity checkpoint#GO:0044774;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=23924|UniProtKB=A6NKD2 A6NKD2 TSPY2 PTHR11875:SF12 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED PROTEIN 1-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=19652|UniProtKB=Q7RTT6 Q7RTT6 SSX6P PTHR14112:SF27 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX6-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=20301|UniProtKB=Q8IZD6 Q8IZD6 SLC22A15 PTHR24064:SF170 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 15 secondary carrier transporter#PC00258 HUMAN|HGNC=8701|UniProtKB=Q9Y5H0 Q9Y5H0 PCDHGA3 PTHR24028:SF234 CADHERIN-87A PROTOCADHERIN GAMMA-A3 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|Ensembl=ENSG00000214897|UniProtKB=A0A0J9YXQ4 A0A0J9YXQ4 PNMA6E PTHR23095:SF20 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN MA6E HUMAN|HGNC=29412|UniProtKB=Q6P995 Q6P995 FAM171B PTHR31626:SF2 FAMILY NOT NAMED PROTEIN FAM171B HUMAN|HGNC=6161|UniProtKB=P18564 P18564 ITGB6 PTHR10082:SF11 INTEGRIN BETA SUBUNIT INTEGRIN BETA-6 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;biological adhesion#GO:0022610;localization of cell#GO:0051674;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052 membrane protein complex#GO:0098796;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;focal adhesion#GO:0005925;integral component of plasma membrane#GO:0005887;cell-substrate junction#GO:0030055;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 HUMAN|HGNC=3559|UniProtKB=P15090 P15090 FABP4 PTHR11955:SF83 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, ADIPOCYTE HUMAN|HGNC=34298|UniProtKB=A6NIV6 A6NIV6 LRRIQ4 PTHR45752:SF46 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 4 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 scaffold/adaptor protein#PC00226 HUMAN|HGNC=33273|UniProtKB=P86452 P86452 ZBED6 PTHR47241:SF2 FINGER PROTEIN, PUTATIVE-RELATED ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 6 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=20611|UniProtKB=Q71RS6 Q71RS6 SLC24A5 PTHR10846:SF61 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM/POTASSIUM/CALCIUM EXCHANGER 5 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;cation:cation antiporter activity#GO:0015491;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;solute:cation antiporter activity#GO:0015298;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=33856|UniProtKB=A6ND91 A6ND91 ASPDH PTHR31873:SF6 L-ASPARTATE DEHYDROGENASE-RELATED L-ASPARTATE DEHYDROGENASE-RELATED dehydrogenase#PC00092 HUMAN|HGNC=6081|UniProtKB=P01308 P01308 INS PTHR11454:SF9 INSULIN/INSULIN GROWTH FACTOR INSULIN growth factor#PC00112 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896;Gonadotropin-releasing hormone receptor pathway#P06664>Insulin#P06793;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882 HUMAN|HGNC=17983|UniProtKB=Q96LB1 Q96LB1 MRGPRX2 PTHR11334:SF29 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MEMBER X2 G-protein coupled receptor#PC00021 HUMAN|HGNC=12968|UniProtKB=Q9ULX5 Q9ULX5 RNF112 PTHR10751:SF1 GUANYLATE BINDING PROTEIN RING FINGER PROTEIN 112 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 heterotrimeric G-protein#PC00117 HUMAN|HGNC=7173|UniProtKB=P08254 P08254 MMP3 PTHR10201:SF215 MATRIX METALLOPROTEINASE STROMELYSIN-1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 CCKR signaling map#P06959>MMP3#P07105;Plasminogen activating cascade#P00050>pro-MMP-3#P01260;Plasminogen activating cascade#P00050>MMP-3#P01251 HUMAN|HGNC=12601|UniProtKB=O75445 O75445 USH2A PTHR10574:SF274 NETRIN/LAMININ-RELATED USHERIN system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;tissue development#GO:0009888 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=9281|UniProtKB=P62136 P62136 PPP1CA PTHR11668:SF377 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-ALPHA CATALYTIC SUBUNIT hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602;Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969 HUMAN|HGNC=8646|UniProtKB=P61457 P61457 PCBD1 PTHR12599:SF13 PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 dehydratase#PC00091 HUMAN|HGNC=3821|UniProtKB=O43524 O43524 FOXO3 PTHR45767:SF4 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 CCKR signaling map#P06959>FOXO3#P07073;PI3 kinase pathway#P00048>FOXO#P01198;Interleukin signaling pathway#P00036>FKHRL1#P00994;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>FKHR#P00898 HUMAN|HGNC=20253|UniProtKB=Q8N6F7 Q8N6F7 GCSAM PTHR35351:SF2 GERMINAL CENTER-ASSOCIATED SIGNALING AND MOTILITY-LIKE PROTEIN GERMINAL CENTER-ASSOCIATED SIGNALING AND MOTILITY PROTEIN immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;activation of immune response#GO:0002253;regulation of locomotion#GO:0040012;regulation of signaling#GO:0023051;B cell receptor signaling pathway#GO:0050853;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;leukocyte migration#GO:0050900;positive regulation of immune response#GO:0050778;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;regulation of leukocyte migration#GO:0002685;regulation of signal transduction#GO:0009966;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;negative regulation of cell motility#GO:2000146;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of cellular component movement#GO:0051270;regulation of cell communication#GO:0010646;negative regulation of locomotion#GO:0040013;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of cell motility#GO:2000145;immune response#GO:0006955;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;localization of cell#GO:0051674;cell communication#GO:0007154;cell motility#GO:0048870;cellular process#GO:0009987;localization#GO:0051179;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;lymphocyte migration#GO:0072676;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of immune system process#GO:0002683;immune response-activating cell surface receptor signaling pathway#GO:0002429;cell migration#GO:0016477;locomotion#GO:0040011 HUMAN|HGNC=20875|UniProtKB=Q8N8Z8 Q8N8Z8 ZNF441 PTHR24379:SF22 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 441 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29286|UniProtKB=Q6UXK2 Q6UXK2 ISLR2 PTHR24366:SF15 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IMMUNOGLOBULIN SUPERFAMILY CONTAINING LEUCINE-RICH REPEAT PROTEIN 2 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=14752|UniProtKB=Q8NGV7 Q8NGV7 OR5H2 PTHR26452:SF836 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5H2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=4479|UniProtKB=Q99705 Q99705 MCHR1 PTHR24229:SF91 NEUROPEPTIDES RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 1 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=4887|UniProtKB=Q6ZVN8 Q6ZVN8 HJV PTHR31428:SF3 RGM DOMAIN FAMILY MEMBER DRAG-1 HEMOJUVELIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=1166|UniProtKB=Q02833 Q02833 RASSF7 PTHR15286:SF11 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 HUMAN|Ensembl=ENSG00000250821|UniProtKB=A0A1B0GW35 A0A1B0GW35 EXOC1L PTHR16092:SF28 SEC3/SYNTAXIN-RELATED EXOCYST COMPLEX COMPONENT 1-RELATED phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;phospholipid binding#GO:0005543;GTP-Rho binding#GO:0017049;phosphatidylinositol phosphate binding#GO:1901981;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;phosphatidylinositol bisphosphate binding#GO:1902936;Ras GTPase binding#GO:0017016;protein binding#GO:0005515;lipid binding#GO:0008289;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167 vesicle fusion#GO:0006906;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;exocytic process#GO:0140029;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;vesicle organization#GO:0016050;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 SNARE protein#PC00034 HUMAN|HGNC=23586|UniProtKB=B3EWG5 B3EWG5 FAM25C PTHR34994:SF1 PROTEIN FAM25A-RELATED PROTEIN FAM25A-RELATED HUMAN|HGNC=9344|UniProtKB=P42785 P42785 PRCP PTHR11010:SF38 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 serine protease#PC00203 HUMAN|HGNC=16476|UniProtKB=Q9H0E2 Q9H0E2 TOLLIP PTHR16461:SF5 TOLL-INTERACTING PROTEIN TOLL-INTERACTING PROTEIN enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Toll receptor signaling pathway#P00054>Tollip#P01379 HUMAN|HGNC=24580|UniProtKB=Q96Q77 Q96Q77 CIB3 PTHR45791:SF7 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 3 HUMAN|HGNC=3801|UniProtKB=Q99958 Q99958 FOXC2 PTHR11829:SF189 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN C2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=16012|UniProtKB=Q96Q27 Q96Q27 ASB2 PTHR24173:SF33 FAMILY NOT NAMED ANKYRIN REPEAT AND SOCS BOX PROTEIN 2 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=33915|UniProtKB=A6NGW2 A6NGW2 STRCP1 PTHR23412:SF14 STEREOCILIN RELATED STEREOCILIN-RELATED cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;biological adhesion#GO:0022610 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;intracellular organelle#GO:0043229;stereocilium#GO:0032420;non-membrane-bounded organelle#GO:0043228;cell surface#GO:0009986;stereocilium bundle#GO:0032421;kinocilium#GO:0060091;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;non-motile cilium#GO:0097730;cluster of actin-based cell projections#GO:0098862;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=405|UniProtKB=P30838 P30838 ALDH3A1 PTHR43570:SF15 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE, DIMERIC NADP-PREFERRING oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=13089|UniProtKB=P17036 P17036 ZNF3 PTHR24381:SF366 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 3-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=27012|UniProtKB=Q6P5X5 Q6P5X5 C22orf39 PTHR28052:SF1 UPF0545 PROTEIN C22ORF39 UPF0545 PROTEIN C22ORF39 HUMAN|HGNC=28629|UniProtKB=Q5BKY9 Q5BKY9 FAM133B PTHR31911:SF3 PROTEIN FAM133 PROTEIN FAM133B RNA metabolism protein#PC00031 HUMAN|HGNC=15580|UniProtKB=Q5VU43 Q5VU43 PDE4DIP PTHR46501:SF2 MYOMEGALIN MYOMEGALIN HUMAN|HGNC=29104|UniProtKB=O94819 O94819 KBTBD11 PTHR45972:SF3 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 11 HUMAN|HGNC=8767|UniProtKB=Q8N8D1 Q8N8D1 PDCD7 PTHR48190:SF2 PROGRAMMED CELL DEATH PROTEIN 7 PROGRAMMED CELL DEATH PROTEIN 7 HUMAN|HGNC=4333|UniProtKB=Q9NZM5 Q9NZM5 NOP53 PTHR14211:SF8 GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2 RIBOSOME BIOGENESIS PROTEIN NOP53 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=19441|UniProtKB=Q8IUF8 Q8IUF8 RIOX2 PTHR13096:SF7 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 2 HUMAN|HGNC=10350|UniProtKB=P62891 P62891 RPL39 PTHR19970:SF25 RIBOSOMAL PROTEIN L39E 60S RIBOSOMAL PROTEIN L39 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=6861|UniProtKB=P80192 P80192 MAP3K9 PTHR44329:SF35 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of JNK cascade#GO:0046330;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;positive regulation of protein serine/threonine kinase activity#GO:0071902;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834 HUMAN|HGNC=21239|UniProtKB=Q9P0B6 Q9P0B6 CCDC167 PTHR31759:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 167 COILED-COIL DOMAIN-CONTAINING PROTEIN 167 HUMAN|HGNC=13681|UniProtKB=Q96JQ0 Q96JQ0 DCHS1 PTHR24027:SF423 CADHERIN-23 PROTOCADHERIN-16 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=19119|UniProtKB=Q8N695 Q8N695 SLC5A8 PTHR42985:SF10 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;organic acid:sodium symporter activity#GO:0005343;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 monocarboxylic acid transport#GO:0015718;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;macromolecule localization#GO:0033036;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;lipid transport#GO:0006869;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;anion transport#GO:0006820;lipid localization#GO:0010876 secondary carrier transporter#PC00258 HUMAN|HGNC=16864|UniProtKB=Q15398 Q15398 DLGAP5 PTHR12353:SF1 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN DISKS LARGE-ASSOCIATED PROTEIN 5 scaffold/adaptor protein#PC00226 HUMAN|HGNC=2358|UniProtKB=Q13324 Q13324 CRHR2 PTHR45620:SF19 PDF RECEPTOR-LIKE PROTEIN-RELATED CORTICOTROPIN-RELEASING FACTOR RECEPTOR 2 signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;axon terminus#GO:0043679;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Cortocotropin releasing factor receptor signaling pathway#P04380>CRHR1#P04451 HUMAN|HGNC=15901|UniProtKB=Q9Y366 Q9Y366 IFT52 PTHR12969:SF7 NGD5/OSM-6/IFT52 INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG HUMAN|HGNC=30711|UniProtKB=Q8IWG1 Q8IWG1 WDR63 PTHR12442:SF5 DYNEIN INTERMEDIATE CHAIN WD REPEAT-CONTAINING PROTEIN 63 dynein heavy chain binding#GO:0045504;protein binding#GO:0005515;binding#GO:0005488 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;inner dynein arm assembly#GO:0036159;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;axonemal dynein complex assembly#GO:0070286;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;cilium movement involved in cell motility#GO:0060294;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 supramolecular complex#GO:0099080;axoneme#GO:0005930;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=26796|UniProtKB=Q96D98 Q96D98 EID2B PTHR15556:SF4 EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 2-RELATED EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 2B molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=652|UniProtKB=P84077 P84077 ARF1 PTHR11711:SF357 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 HUMAN|HGNC=30704|UniProtKB=Q96KD3 Q96KD3 FAM71F1 PTHR22574:SF13 UNCHARACTERIZED PROTEIN FAM71F1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=12962|UniProtKB=Q12899 Q12899 TRIM26 PTHR24103:SF369 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 26 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;innate immune response#GO:0045087;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=3157|UniProtKB=Q92838 Q92838 EDA PTHR15151:SF13 PROTEIN EIGER ECTODYSPLASIN-A receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;molecular function regulator#GO:0098772;protein binding#GO:0005515;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of NIK/NF-kappaB signaling#GO:1901222;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;odontogenesis of dentin-containing tooth#GO:0042475;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NIK/NF-kappaB signaling#GO:1901224;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;NIK/NF-kappaB signaling#GO:0038061;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 HUMAN|HGNC=4426|UniProtKB=Q08378 Q08378 GOLGA3 PTHR18902:SF26 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED GOLGIN SUBFAMILY A MEMBER 3 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=26606|UniProtKB=A6NJ78 A6NJ78 METTL15 PTHR11265:SF1 S-ADENOSYL-METHYLTRANSFERASE MRAW 12S RRNA N4-METHYLCYTIDINE (M4C) METHYLTRANSFERASE-RELATED catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 methyltransferase#PC00155 HUMAN|HGNC=23820|UniProtKB=Q96AV8 Q96AV8 E2F7 PTHR12081:SF25 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=4948|UniProtKB=P01911 P01911 HLA-DRB1 PTHR19944:SF99 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1 BETA CHAIN major histocompatibility complex protein#PC00149 HUMAN|HGNC=9672|UniProtKB=Q9HD43 Q9HD43 PTPRH PTHR19134:SF297 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE H hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of MAP kinase activity#GO:0043407;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 protein phosphatase#PC00195 HUMAN|HGNC=16939|UniProtKB=O95391 O95391 SLU7 PTHR12942:SF2 STEP II SPLICING FACTOR SLU7 PRE-MRNA-SPLICING FACTOR SLU7 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=24978|UniProtKB=Q96KN8 Q96KN8 PLAAT5 PTHR13943:SF2 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 5 transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=19312|UniProtKB=Q56P03 Q56P03 EAPP PTHR15967:SF0 UNCHARACTERIZED E2F-ASSOCIATED PHOSPHOPROTEIN regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=6248|UniProtKB=Q9UIX4 Q9UIX4 KCNG1 PTHR11537:SF88 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY G MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;potassium ion transmembrane transporter activity#GO:0015079;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 regulation of metal ion transport#GO:0010959;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;regulation of potassium ion transport#GO:0043266;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of potassium ion transmembrane transport#GO:1901379;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;potassium ion transport#GO:0006813;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;monovalent inorganic cation transport#GO:0015672;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;ion transport#GO:0006811;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;regulation of ion transport#GO:0043269 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=15595|UniProtKB=A0AV02 A0AV02 SLC12A8 PTHR11827:SF6 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 8 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;metal ion transport#GO:0030001;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;chloride transport#GO:0006821;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;regulation of cellular component size#GO:0032535;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065 secondary carrier transporter#PC00258 HUMAN|HGNC=33998|UniProtKB=F5H284 F5H284 PPIAL4D PTHR11071:SF466 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A-LIKE 4C-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=25885|UniProtKB=Q9H7R5 Q9H7R5 ZNF665 PTHR24377:SF609 IP01015P-RELATED ZINC FINGER PROTEIN 665 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2239|UniProtKB=Q9UNS2 Q9UNS2 COPS3 PTHR10758:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 COP9 SIGNALOSOME COMPLEX SUBUNIT 3 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 HUMAN|Ensembl=ENSG00000282639|UniProtKB=A0A0J9YX35 A0A0J9YX35 IGHV3-64D PTHR23266:SF339 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-23-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=29814|UniProtKB=Q96NY9 Q96NY9 MUS81 PTHR13451:SF0 CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81 CROSSOVER JUNCTION ENDONUCLEASE MUS81 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;endodeoxyribonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;deoxyribonuclease activity#GO:0004536 DNA repair#GO:0006281;nuclear division#GO:0000280;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;mitotic DNA integrity checkpoint#GO:0044774;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;reproduction#GO:0000003;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;intra-S DNA damage checkpoint#GO:0031573;mitotic cell cycle process#GO:1903047;meiotic chromosome separation#GO:0051307;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;reciprocal meiotic recombination#GO:0007131;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;cell cycle phase#GO:0022403;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;mitotic DNA damage checkpoint#GO:0044773;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;biological phase#GO:0044848;homologous recombination#GO:0035825;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=8125|UniProtKB=O15527 O15527 OGG1 PTHR10242:SF2 8-OXOGUANINE DNA GLYCOSYLASE N-GLYCOSYLASE/DNA LYASE DNA metabolism protein#PC00009 HUMAN|HGNC=17877|UniProtKB=Q9HAN9 Q9HAN9 NMNAT1 PTHR12039:SF19 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE/NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 1 adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 nucleotidyltransferase#PC00174 HUMAN|HGNC=27051|UniProtKB=Q6ZTI6 Q6ZTI6 RFLNA PTHR31848:SF0 FAMILY NOT NAMED REFILIN-A cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 negative regulation of biological process#GO:0048519;animal organ development#GO:0048513;developmental process#GO:0032502;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;regulation of cell differentiation#GO:0045595;bone mineralization#GO:0030282;bone development#GO:0060348;regulation of biological process#GO:0050789;system development#GO:0048731;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;biomineral tissue development#GO:0031214;negative regulation of cellular process#GO:0048523;regulation of ossification#GO:0030278;cellular developmental process#GO:0048869;biomineralization#GO:0110148;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;ossification#GO:0001503;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;chondrocyte differentiation#GO:0002062;connective tissue development#GO:0061448;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cartilage development#GO:0051216 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 HUMAN|HGNC=2398|UniProtKB=P43320 P43320 CRYBB2 PTHR11818:SF11 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B2 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=17679|UniProtKB=Q9HD47 Q9HD47 RANGRF PTHR15837:SF0 RAN GUANINE NUCLEOTIDE RELEASE FACTOR RAN GUANINE NUCLEOTIDE RELEASE FACTOR HUMAN|HGNC=28764|UniProtKB=Q9BVV2 Q9BVV2 FNDC11 PTHR14537:SF0 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 11 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 11 HUMAN|HGNC=16894|UniProtKB=Q14728 Q14728 MFSD10 PTHR23504:SF31 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 HUMAN|HGNC=39125|UniProtKB=Q8IYP2 Q8IYP2 PRSS58 PTHR24271:SF56 KALLIKREIN-RELATED SERINE PROTEASE 58 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=20410|UniProtKB=Q8TE96 Q8TE96 DQX1 PTHR18934:SF108 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DQX1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA helicase#PC00032 HUMAN|HGNC=10771|UniProtKB=Q15427 Q15427 SF3B4 PTHR48030:SF4 SPLICING FACTOR 3B SUBUNIT 4 SPLICING FACTOR 3B SUBUNIT 4 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;positive regulation of cellular metabolic process#GO:0031325;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;positive regulation of RNA metabolic process#GO:0051254;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;U12-type spliceosomal complex#GO:0005689 RNA splicing factor#PC00148 HUMAN|HGNC=1359|UniProtKB=Q9NQ60 Q9NQ60 EQTN PTHR36874:SF1 EQUATORIN EQUATORIN HUMAN|Ensembl=ENSG00000275798|UniProtKB=A0A0G2JPB7 A0A0G2JPB7 ENSG00000275798 PTHR24100:SF105 BUTYROPHILIN BTNL2-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=25415|UniProtKB=Q8N3J5 Q8N3J5 PPM1K PTHR47992:SF26 ALPHABET, ISOFORM E-RELATED PROTEIN PHOSPHATASE 1K, MITOCHONDRIAL HUMAN|HGNC=8750|UniProtKB=Q00537 Q00537 CDK17 PTHR24056:SF128 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 17 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=9127|UniProtKB=O95744 O95744 PMS2P2 PTHR10073:SF52 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MISMATCH REPAIR ENDONUCLEASE PMS2-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=16121|UniProtKB=Q9BQN1 Q9BQN1 FAM83C PTHR16181:SF24 UNCHARACTERIZED PROTEIN FAM83C HUMAN|HGNC=28725|UniProtKB=Q8IXN7 Q8IXN7 RIMKLA PTHR21621:SF1 RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN N-ACETYLASPARTYLGLUTAMATE SYNTHASE A ligase activity#GO:0016874;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ribosomal protein#PC00202 HUMAN|HGNC=16228|UniProtKB=Q96RU7 Q96RU7 TRIB3 PTHR22961:SF14 SER/THR PROTEIN KINASE-TRB TRIBBLES HOMOLOG 3 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;regulation of intracellular signal transduction#GO:1902531;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;intracellular signal transduction#GO:0035556;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;positive regulation of proteasomal protein catabolic process#GO:1901800;organonitrogen compound catabolic process#GO:1901565;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;catabolic process#GO:0009056;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;signaling#GO:0023052;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of proteasomal protein catabolic process#GO:0061136;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of transferase activity#GO:0051338;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|Ensembl=ENSG00000268655|UniProtKB=A0A1B0GTJ6 A0A1B0GTJ6 ENSG00000268655 PTHR37404:SF1 HCG1796489 HCG1796489 HUMAN|HGNC=11858|UniProtKB=O43657 O43657 TSPAN6 PTHR19282:SF169 TETRASPANIN TETRASPANIN-6 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=19348|UniProtKB=Q9NYM9 Q9NYM9 BET1L PTHR12791:SF37 GOLGI SNARE BET1-RELATED BET1-LIKE PROTEIN molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 endosomal transport#GO:0016197;cellular localization#GO:0051641;transport#GO:0006810;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;cytosolic transport#GO:0016482;regulation of vesicle-mediated transport#GO:0060627;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 membrane protein complex#GO:0098796;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;SNARE complex#GO:0031201;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 SNARE protein#PC00034 HUMAN|HGNC=6919|UniProtKB=O95243 O95243 MBD4 PTHR15074:SF7 METHYL-CPG-BINDING PROTEIN METHYL-CPG-BINDING DOMAIN PROTEIN 4 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=9937|UniProtKB=P35243 P35243 RCVRN PTHR23055:SF20 CALCIUM BINDING PROTEINS RECOVERIN Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Recoverin#P00756 HUMAN|HGNC=20994|UniProtKB=Q7Z7L9 Q7Z7L9 ZSCAN2 PTHR24381:SF380 ZINC FINGER PROTEIN ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 2 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7048|UniProtKB=Q9UQ53 Q9UQ53 MGAT4B PTHR12062:SF1 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum#GO:0005783;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=19420|UniProtKB=Q8TAV4 Q8TAV4 STOML3 PTHR10264:SF49 BAND 7 PROTEIN-RELATED STOMATIN-LIKE PROTEIN 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=4550|UniProtKB=Q13227 Q13227 GPS2 PTHR22654:SF2 G PROTEIN PATHWAY SUPPRESSOR 2 G PROTEIN PATHWAY SUPPRESSOR 2 protein-binding activity modulator#PC00095 HUMAN|HGNC=10252|UniProtKB=O75116 O75116 ROCK2 PTHR22988:SF28 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;GTPase binding#GO:0051020;enzyme binding#GO:0019899;GTP-Rho binding#GO:0017049;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;kinase activity#GO:0016301;protein kinase activity#GO:0004672;Ras GTPase binding#GO:0017016;transferase activity#GO:0016740;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;nuclear division#GO:0000280;Ras protein signal transduction#GO:0007265;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cell communication#GO:0007154;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;embryo development#GO:0009790;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cell division#GO:0051301;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;cell cycle process#GO:0022402;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;mitotic cytokinesis#GO:0000281;cell junction assembly#GO:0034329;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;cytokinesis#GO:0000910;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;membrane fission#GO:0090148;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;Rho protein signal transduction#GO:0007266;response to stimulus#GO:0050896;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;cell junction organization#GO:0034330;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell junction assembly#GO:1901888;actin cytoskeleton organization#GO:0030036;embryonic morphogenesis#GO:0048598;cortical actin cytoskeleton organization#GO:0030866 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519 HUMAN|HGNC=13155|UniProtKB=P51504 P51504 ZNF80 PTHR24381:SF111 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 80 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1694|UniProtKB=Q07108 Q07108 CD69 PTHR45710:SF8 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 EARLY ACTIVATION ANTIGEN CD69 HUMAN|HGNC=374|UniProtKB=Q5JQC9 Q5JQC9 AKAP4 PTHR10226:SF8 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN 4 protein kinase A binding#GO:0051018;protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;macromolecule localization#GO:0033036;protein localization#GO:0008104 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;C2 axonemal microtubule#GO:1990720;B axonemal microtubule#GO:0097650;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;sperm principal piece#GO:0097228;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;axonemal microtubule#GO:0005879 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26159|UniProtKB=A4D0V7 A4D0V7 CPED1 PTHR14776:SF1 CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1 CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=2900|UniProtKB=Q12959 Q12959 DLG1 PTHR23119:SF5 DISCS LARGE DISKS LARGE HOMOLOG 1 establishment or maintenance of cell polarity#GO:0007163;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;developmental process#GO:0032502;biological adhesion#GO:0022610;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to organelle#GO:0033365;cell-cell signaling#GO:0007267;signaling#GO:0023052;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;embryo development#GO:0009790;cellular macromolecule localization#GO:0070727;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;receptor clustering#GO:0043113;establishment or maintenance of bipolar cell polarity#GO:0061245;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;neuromuscular junction#GO:0031594;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;basolateral plasma membrane#GO:0016323;ion channel complex#GO:0034702;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9203|UniProtKB=Q6PJE2 Q6PJE2 POMZP3 PTHR11576:SF2 ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 POM121 AND ZP3 FUSION PROTEIN-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 germ cell development#GO:0007281;cell recognition#GO:0008037;cellular developmental process#GO:0048869;fertilization#GO:0009566;gamete generation#GO:0007276;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;regulation of reproductive process#GO:2000241;cellular process#GO:0009987;multi-organism process#GO:0051704;cell-cell recognition#GO:0009988;regulation of biological process#GO:0050789;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cell differentiation#GO:0030154;reproduction#GO:0000003;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;regulation of multi-organism process#GO:0043900;sperm-egg recognition#GO:0035036;multi-organism reproductive process#GO:0044703;positive regulation of biological process#GO:0048518;binding of sperm to zona pellucida#GO:0007339;multicellular organismal reproductive process#GO:0048609;acrosome reaction#GO:0007340 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=14303|UniProtKB=A4UGR9 A4UGR9 XIRP2 PTHR22591:SF1 XIN XIN ACTIN-BINDING REPEAT-CONTAINING PROTEIN 2 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=24504|UniProtKB=Q63HN1 Q63HN1 FAM205BP PTHR21859:SF15 ACROSOME-SPECIFIC PROTEIN PROTEIN FAM205A-RELATED HUMAN|HGNC=9077|UniProtKB=P53350 P53350 PLK1 PTHR24345:SF0 SERINE/THREONINE-PROTEIN KINASE PLK SERINE/THREONINE-PROTEIN KINASE PLK1 cell division#GO:0051301;membrane fission#GO:0090148;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;regulation of cell division#GO:0051302;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of cytokinesis#GO:0032465;cytokinesis#GO:0000910 spindle pole#GO:0000922;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=11522|UniProtKB=O75410 O75410 TACC1 PTHR13924:SF12 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 1 head development#GO:0060322;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;brain development#GO:0007420;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;cell population proliferation#GO:0008283;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;forebrain development#GO:0030900;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;central nervous system development#GO:0007417 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=14376|UniProtKB=Q9BZG2 Q9BZG2 ACP4 PTHR11567:SF145 ACID PHOSPHATASE-RELATED TESTICULAR ACID PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;phosphoprotein phosphatase activity#GO:0004721;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;vacuole organization#GO:0007033;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;regulation of synaptic plasticity#GO:0048167;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;negative regulation of signal transduction#GO:0009968;regulation of trans-synaptic signaling#GO:0099177;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;lysosome organization#GO:0007040;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 synapse#GO:0045202;postsynaptic membrane#GO:0045211;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;synaptic membrane#GO:0097060;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;postsynapse#GO:0098794;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=16052|UniProtKB=Q8N0Y2 Q8N0Y2 ZNF444 PTHR23226:SF150 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 444 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21754|UniProtKB=Q9H2L4 Q9H2L4 TMEM60 PTHR13568:SF4 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 60 HUMAN|HGNC=19304|UniProtKB=O95104 O95104 SCAF4 PTHR23140:SF3 RNA PROCESSING PROTEIN LD23810P SR-RELATED AND CTD-ASSOCIATED FACTOR 4 RNA processing factor#PC00147 HUMAN|HGNC=12404|UniProtKB=P49638 P49638 TTPA PTHR10174:SF225 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transfer/carrier protein#PC00219 HUMAN|HGNC=11309|UniProtKB=P78539 P78539 SRPX PTHR46343:SF1 FAMILY NOT NAMED SUSHI REPEAT-CONTAINING PROTEIN SRPX HUMAN|HGNC=12307|UniProtKB=Q15645 Q15645 TRIP13 PTHR45991:SF1 PACHYTENE CHECKPOINT PROTEIN 2 PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;regulation of cellular component organization#GO:0051128;negative regulation of cell cycle process#GO:0010948;negative regulation of nuclear division#GO:0051784;nucleobase-containing compound metabolic process#GO:0006139;M phase#GO:0000279;regulation of biological process#GO:0050789;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;negative regulation of cellular component organization#GO:0051129;cell cycle phase#GO:0022403;negative regulation of cellular process#GO:0048523;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;meiosis I cell cycle phase#GO:0098764;regulation of nuclear division#GO:0051783;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;negative regulation of cell cycle#GO:0045786;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;regulation of meiotic cell cycle#GO:0051445;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;homologous recombination#GO:0035825;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=8024|UniProtKB=P34130 P34130 NTF4 PTHR11589:SF8 NERVE GROWTH FACTOR NGF -RELATED NEUROTROPHIN-4 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;protein binding#GO:0005515;molecular function regulator#GO:0098772;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 neuron apoptotic process#GO:0051402;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;system process#GO:0003008;positive regulation of cellular metabolic process#GO:0031325;neuron death#GO:0070997;positive regulation of protein modification process#GO:0031401;negative regulation of neuron death#GO:1901215;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cognition#GO:0050890;apoptotic process#GO:0006915;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;positive regulation of macromolecule metabolic process#GO:0010604;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;negative regulation of cell death#GO:0060548;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of neuron death#GO:1901214;response to growth factor#GO:0070848;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;behavior#GO:0007610;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of apoptotic process#GO:0042981;cellular response to chemical stimulus#GO:0070887;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;nervous system process#GO:0050877;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;peptidyl-serine modification#GO:0018209;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270 neurotrophic factor#PC00163 HUMAN|HGNC=9009|UniProtKB=Q13563 Q13563 PKD2 PTHR10877:SF114 POLYCYSTIN FAMILY MEMBER POLYCYSTIN-2 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;cytoskeletal protein binding#GO:0008092;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;metal ion binding#GO:0046872;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;signaling receptor binding#GO:0005102;voltage-gated calcium channel activity#GO:0005245;cation binding#GO:0043169;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;detection of mechanical stimulus#GO:0050982;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;sequestering of calcium ion#GO:0051208;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;response to abiotic stimulus#GO:0009628;negative regulation of cellular process#GO:0048523;potassium ion transport#GO:0006813;cellular cation homeostasis#GO:0030003;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;release of sequestered calcium ion into cytosol#GO:0051209;homeostatic process#GO:0042592;detection of stimulus#GO:0051606;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;regulation of cytosolic calcium ion concentration#GO:0051480;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;calcium ion transport into cytosol#GO:0060402;response to external stimulus#GO:0009605;response to mechanical stimulus#GO:0009612;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065;negative regulation of sequestering of calcium ion#GO:0051283 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133 HUMAN|HGNC=4298|UniProtKB=P16278 P16278 GLB1 PTHR23421:SF172 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 galactosidase#PC00104 HUMAN|HGNC=28032|UniProtKB=Q5J8M3 Q5J8M3 EMC4 PTHR19315:SF9 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 cellular process#GO:0009987;protein folding#GO:0006457 membrane protein complex#GO:0098796;ER membrane protein complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=7760|UniProtKB=Q9UQ49 Q9UQ49 NEU3 PTHR10628:SF23 SIALIDASE SIALIDASE-3 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carbohydrate metabolic process#GO:0005975;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 hydrolase#PC00121 HUMAN|HGNC=9326|UniProtKB=Q9UMR5 Q9UMR5 PPT2 PTHR11247:SF27 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 LYSOSOMAL THIOESTERASE PPT2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 HUMAN|HGNC=10880|UniProtKB=P40967 P40967 PMEL PTHR11861:SF1 MELANOCYTE PROTEIN PMEL 17-RELATED MELANOCYTE PROTEIN PMEL pigmentation#GO:0043473;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;melanosome organization#GO:0032438 intracellular vesicle#GO:0097708;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=3624|UniProtKB=Q15485 Q15485 FCN2 PTHR19143:SF346 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-2 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=25546|UniProtKB=Q9NVR7 Q9NVR7 TBCCD1 PTHR16052:SF0 UNCHARACTERIZED TBCC DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=6758|UniProtKB=Q9Y586 Q9Y586 MAB21L2 PTHR10656:SF37 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE 2 HUMAN|HGNC=868|UniProtKB=Q15904 Q15904 ATP6AP1 PTHR12471:SF2 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1 inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;plasma membrane#GO:0005886 ATP synthase#PC00002 HUMAN|HGNC=14368|UniProtKB=Q9GZN4 Q9GZN4 PRSS22 PTHR24253:SF6 TRANSMEMBRANE PROTEASE SERINE BRAIN-SPECIFIC SERINE PROTEASE 4 serine protease#PC00203 HUMAN|HGNC=30563|UniProtKB=Q7L3T8 Q7L3T8 PARS2 PTHR42753:SF2 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER PROLINE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=28952|UniProtKB=P42695 P42695 NCAPD3 PTHR14222:SF1 CONDENSIN CONDENSIN-2 COMPLEX SUBUNIT D3 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic chromosome condensation#GO:0007076;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;chromosome organization involved in meiotic cell cycle#GO:0070192;DNA packaging#GO:0006323;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic cell cycle process#GO:1903046;reproductive process#GO:0022414;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;chromosomal region#GO:0098687 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=23154|UniProtKB=Q7Z7K2 Q7Z7K2 ZNF467 PTHR24377:SF890 IP01015P-RELATED ZINC FINGER PROTEIN 467 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=30224|UniProtKB=Q9HAB3 Q9HAB3 SLC52A2 PTHR12929:SF1 SOLUTE CARRIER FAMILY 52 SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 2 anion transmembrane transporter activity#GO:0008509;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=5394|UniProtKB=P05156 P05156 CFI PTHR24253:SF91 TRANSMEMBRANE PROTEASE SERINE COMPLEMENT FACTOR I serine protease#PC00203 HUMAN|HGNC=28563|UniProtKB=Q53QW1 Q53QW1 TEX44 PTHR37365:SF1 TESTIS-EXPRESSED PROTEIN 44 TESTIS-EXPRESSED PROTEIN 44 HUMAN|HGNC=15174|UniProtKB=Q8NGI4 Q8NGI4 OR4D11 PTHR48002:SF89 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4D11 transmembrane signal receptor#PC00197 HUMAN|HGNC=10917|UniProtKB=Q13183 Q13183 SLC13A2 PTHR10283:SF66 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 2 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=24575|UniProtKB=Q9Y248 Q9Y248 GINS2 PTHR12772:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 pyrophosphatase activity#GO:0016462;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;double-strand break repair via break-induced replication#GO:0000727;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;pre-replicative complex#GO:0036387;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear pre-replicative complex#GO:0005656;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 HUMAN|HGNC=10025|UniProtKB=Q13129 Q13129 RLF PTHR15507:SF18 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN RLF sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28779|UniProtKB=Q86WS5 Q86WS5 TMPRSS12 PTHR24253:SF127 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 12 serine protease#PC00203 HUMAN|HGNC=21263|UniProtKB=Q96FT7 Q96FT7 ASIC4 PTHR11690:SF13 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=21202|UniProtKB=Q6ZMV9 Q6ZMV9 KIF6 PTHR24115:SF194 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF6 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=21384|UniProtKB=Q9NUH8 Q9NUH8 TMEM14B PTHR12668:SF20 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14B localization#GO:0051179;mitochondrial transport#GO:0006839;establishment of localization#GO:0051234;transport#GO:0006810 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 HUMAN|HGNC=1874|UniProtKB=P23528 P23528 CFL1 PTHR11913:SF17 COFILIN-RELATED COFILIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 protein-containing complex disassembly#GO:0032984;cellular protein complex disassembly#GO:0043624;actin polymerization or depolymerization#GO:0008154;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;locomotion#GO:0040011;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;actin cortical patch#GO:0030479;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Cofilin#P00508 HUMAN|HGNC=17003|UniProtKB=Q9Y6Q2 Q9Y6Q2 STON1 PTHR10529:SF339 AP COMPLEX SUBUNIT MU STONIN-1 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;clathrin binding#GO:0030276;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;regulation of endocytosis#GO:0030100;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;transport#GO:0006810;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;receptor-mediated endocytosis#GO:0006898;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;plasma membrane protein complex#GO:0098797;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;AP-type membrane coat adaptor complex#GO:0030119;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;plasma membrane region#GO:0098590;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=13417|UniProtKB=Q9Y5P8 Q9Y5P8 PPP2R3B PTHR14095:SF1 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT BETA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 protein phosphatase#PC00195 HUMAN|HGNC=11827|UniProtKB=Q07157 Q07157 TJP1 PTHR13865:SF25 TIGHT JUNCTION PROTEIN TIGHT JUNCTION PROTEIN ZO-1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 blood circulation#GO:0008015;cell-cell junction organization#GO:0045216;cellular developmental process#GO:0048869;macromolecule localization#GO:0033036;epithelium development#GO:0060429;system process#GO:0003008;developmental process#GO:0032502;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;homeostatic process#GO:0042592;cell adhesion#GO:0007155;cellular component organization#GO:0016043;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;circulatory system process#GO:0003013;tissue development#GO:0009888;protein localization#GO:0008104;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;multicellular organismal homeostasis#GO:0048871;tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;protein localization to cell junction#GO:1902414;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446;anatomical structure homeostasis#GO:0060249 anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical junction complex#GO:0043296 tight junction#PC00214 HUMAN|HGNC=43623|UniProtKB=A0A1W2PQC6 A0A1W2PQC6 SSU72P4 PTHR20383:SF10 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;mRNA 3'-end processing#GO:0031124;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;mRNA polyadenylation#GO:0006378;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;dephosphorylation#GO:0016311;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 protein phosphatase#PC00195 HUMAN|HGNC=27056|UniProtKB=Q6KB66 Q6KB66 KRT80 PTHR45616:SF1 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 80 HUMAN|HGNC=28994|UniProtKB=Q8NBF6 Q8NBF6 AVL9 PTHR31017:SF1 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED LATE SECRETORY PATHWAY PROTEIN AVL9 HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=6550|UniProtKB=O14960 O14960 LECT2 PTHR11329:SF0 LEUKOCYTE CELL-DERIVED CHEMOTAXIN 2 LEUKOCYTE CELL-DERIVED CHEMOTAXIN-2 chemokine#PC00074 HUMAN|HGNC=29205|UniProtKB=Q969X5 Q969X5 ERGIC1 PTHR10984:SF36 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 1 HUMAN|HGNC=23734|UniProtKB=Q7RTS3 Q7RTS3 PTF1A PTHR23349:SF59 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST PANCREAS TRANSCRIPTION FACTOR 1 SUBUNIT ALPHA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=27023|UniProtKB=A6NMZ7 A6NMZ7 COL6A6 PTHR22588:SF5 UNCHARACTERIZED COLLAGEN ALPHA-6(VI) CHAIN Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=8673|UniProtKB=Q9UN72 Q9UN72 PCDHA7 PTHR24028:SF225 CADHERIN-87A PROTOCADHERIN ALPHA-7 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=7672|UniProtKB=O75376 O75376 NCOR1 PTHR13992:SF5 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR NUCLEAR RECEPTOR COREPRESSOR 1-RELATED binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;DNA-binding transcription factor binding#GO:0140297 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>N-CoR#P00770 HUMAN|HGNC=14820|UniProtKB=Q8NGX6 Q8NGX6 OR10R2 PTHR26451:SF42 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10R2 HUMAN|HGNC=17305|UniProtKB=Q9Y6J9 Q9Y6J9 TAF6L PTHR10221:SF9 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TAF6-LIKE RNA POLYMERASE II P300/CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 6L transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;RNA polymerase II general transcription initiation factor activity#GO:0016251 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;General transcription regulation#P00023>TBP#P00670;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 HUMAN|HGNC=17088|UniProtKB=Q7Z460 Q7Z460 CLASP1 PTHR21567:SF28 CLASP CLIP-ASSOCIATING PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;mitotic spindle assembly#GO:0090307;regulation of microtubule cytoskeleton organization#GO:0070507;spindle assembly#GO:0051225;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;organelle fission#GO:0048285;cell cycle#GO:0007049 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;spindle microtubule#GO:0005876;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=29380|UniProtKB=Q96ME7 Q96ME7 ZNF512 PTHR22979:SF2 ZINC FINGER PROTEIN-RELATED ZINC FINGER PROTEIN 512 HUMAN|HGNC=17684|UniProtKB=Q9NVT9 Q9NVT9 ARMC1 PTHR46840:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 1 ARMADILLO REPEAT-CONTAINING PROTEIN 1 HUMAN|HGNC=18463|UniProtKB=Q8IZA3 Q8IZA3 H1-8 PTHR11467:SF42 HISTONE H1 HISTONE H1.8 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of chromatin silencing#GO:0031935;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of chromatin silencing#GO:0031936;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of chromatin organization#GO:1902275;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;chromosome condensation#GO:0030261;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of DNA recombination#GO:0000018;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone#PC00118 HUMAN|HGNC=26184|UniProtKB=Q9H6E5 Q9H6E5 TUT1 PTHR12271:SF127 POLY A POLYMERASE CID PAP -RELATED SPECKLE TARGETED PIP5K1A-REGULATED POLY(A) POLYMERASE adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 HUMAN|HGNC=9440|UniProtKB=O43422 O43422 THAP12 PTHR46289:SF8 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE HUMAN|HGNC=6118|UniProtKB=Q14653 Q14653 IRF3 PTHR11949:SF1 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 Toll receptor signaling pathway#P00054>IRF3#P01374 HUMAN|HGNC=12145|UniProtKB=A0A075B6U4 A0A075B6U4 TRAV7 PTHR19433:SF114 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 20-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=6289|UniProtKB=Q86W47 Q86W47 KCNMB4 PTHR10258:SF3 CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT BETA-4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;transporter activity#GO:0005215;channel activity#GO:0015267;calcium-activated potassium channel activity#GO:0015269;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 response to metal ion#GO:0010038;detection of stimulus#GO:0051606;response to stimulus#GO:0050896;response to inorganic substance#GO:0010035;response to chemical#GO:0042221;detection of chemical stimulus#GO:0009593 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=1757|UniProtKB=Q13634 Q13634 CDH18 PTHR24027:SF106 CADHERIN-23 CADHERIN-18 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=30797|UniProtKB=Q92544 Q92544 TM9SF4 PTHR10766:SF143 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 4 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=24573|UniProtKB=Q8TAT5 Q8TAT5 NEIL3 PTHR22993:SF10 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA glycosylase#PC00010 HUMAN|HGNC=10920|UniProtKB=P46059 P46059 SLC15A1 PTHR11654:SF89 OLIGOPEPTIDE TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 15 MEMBER 1 transporter#PC00227 HUMAN|HGNC=3706|UniProtKB=O43520 O43520 ATP8B1 PTHR24092:SF48 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IC pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;organelle organization#GO:0006996;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=1770|UniProtKB=Q15131 Q15131 CDK10 PTHR24056:SF508 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 10 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=19154|UniProtKB=Q9UKL4 Q9UKL4 GJD2 PTHR11984:SF32 CONNEXIN GAP JUNCTION DELTA-2 PROTEIN gap junction#PC00105 HUMAN|HGNC=8689|UniProtKB=Q9Y5E5 Q9Y5E5 PCDHB4 PTHR24028:SF55 CADHERIN-87A PROTOCADHERIN BETA-4 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=28420|UniProtKB=Q9BQD3 Q9BQD3 KXD1 PTHR13511:SF0 UNCHARACTERIZED KXDL MOTIF-CONTAINING PROTEIN 1 lysosome localization#GO:0032418;localization#GO:0051179;cellular localization#GO:0051641;organelle localization#GO:0051640;cellular process#GO:0009987 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622;BLOC-1 complex#GO:0031083 HUMAN|HGNC=2290|UniProtKB=O60397 O60397 COX7A2P2 PTHR10510:SF14 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A3, MITOCHONDRIAL-RELATED ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular component biogenesis#GO:0044085;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;protein-containing complex subunit organization#GO:0043933;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;regulation of phosphorylation#GO:0042325;nucleoside phosphate biosynthetic process#GO:1901293;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;regulation of phosphate metabolic process#GO:0019220;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;organelle organization#GO:0006996;oxidative phosphorylation#GO:0006119;biological regulation#GO:0065007;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227 oxidase#PC00175 HUMAN|HGNC=7943|UniProtKB=P16066 P16066 NPR1 PTHR11920:SF300 GUANYLYL CYCLASE ATRIAL NATRIURETIC PEPTIDE RECEPTOR 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide hormone binding#GO:0017046;peptide receptor activity#GO:0001653;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;organophosphate biosynthetic process#GO:0090407;cyclic nucleotide metabolic process#GO:0009187;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 guanylate cyclase#PC00114 HUMAN|HGNC=6780|UniProtKB=Q9ULX9 Q9ULX9 MAFF PTHR10129:SF25 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFF cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;epidermis development#GO:0008544;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of epithelial cell differentiation#GO:0030856;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;epidermal cell differentiation#GO:0009913;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;epithelial cell differentiation#GO:0030855;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;tissue development#GO:0009888;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=21152|UniProtKB=Q496Y0 Q496Y0 LONRF3 PTHR23327:SF41 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 3 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=14979|UniProtKB=Q15036 Q15036 SNX17 PTHR12431:SF16 SORTING NEXIN 17 AND 27 SORTING NEXIN-17 lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;retrograde transport, endosome to plasma membrane#GO:1990126;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=21021|UniProtKB=Q5SYE7 Q5SYE7 NHSL1 PTHR23039:SF3 NANCE-HORAN SYNDROME PROTEIN NHS-LIKE PROTEIN 1 cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 HUMAN|HGNC=14555|UniProtKB=Q9ULY5 Q9ULY5 CLEC4E PTHR22802:SF402 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER E membrane traffic protein#PC00150 HUMAN|HGNC=18676|UniProtKB=Q86XP3 Q86XP3 DDX42 PTHR24031:SF125 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX42 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=26137|UniProtKB=Q6NT76 Q6NT76 HMBOX1 PTHR14618:SF0 HOMEODOX-CONTAINING PROTEIN 1 HMBOX1 HOMEOBOX-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=8088|UniProtKB=Q9Y6K5 Q9Y6K5 OAS3 PTHR11258:SF4 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE 3 adenylyltransferase activity#GO:0070566;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;double-stranded RNA binding#GO:0003725 response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA phosphodiester bond hydrolysis#GO:0090501;regulation of catalytic activity#GO:0050790;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;defense response to other organism#GO:0098542;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 HUMAN|HGNC=1381|UniProtKB=P43166 P43166 CA7 PTHR18952:SF124 CARBONIC ANHYDRASE CARBONIC ANHYDRASE 7 carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=10735|UniProtKB=Q9NTN9 Q9NTN9 SEMA4G PTHR11036:SF17 SEMAPHORIN SEMAPHORIN-4G receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=43746|UniProtKB=D6RGX4 D6RGX4 FAM90A26 PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=23148|UniProtKB=Q9NUJ7 Q9NUJ7 PLCXD1 PTHR13593:SF24 UNCHARACTERIZED PI-PLC X DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=14349|UniProtKB=Q9P0V9 Q9P0V9 SEPTIN10 PTHR18884:SF50 SEPTIN SEPTIN-10 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cell division#GO:0051301;cellular localization#GO:0051641;membrane fission#GO:0090148;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytokinesis#GO:0000910 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 HUMAN|HGNC=16059|UniProtKB=O96013 O96013 PAK4 PTHR48015:SF17 SERINE/THREONINE-PROTEIN KINASE TAO SERINE/THREONINE-PROTEIN KINASE PAK 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517 HUMAN|HGNC=17371|UniProtKB=Q5TD97 Q5TD97 FHL5 PTHR24205:SF7 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 5 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 supramolecular complex#GO:0099080;nucleus#GO:0005634;Z disc#GO:0030018;intracellular membrane-bounded organelle#GO:0043231;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;myofibril#GO:0030016;I band#GO:0031674 transcription cofactor#PC00217 HUMAN|HGNC=18705|UniProtKB=P47944 P47944 MT4 PTHR23299:SF12 METALLOTHIONEIN METALLOTHIONEIN-4 cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;transition metal ion homeostasis#GO:0055076;response to metal ion#GO:0010038;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;response to toxic substance#GO:0009636;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=31823|UniProtKB=Q5T749 Q5T749 KPRP PTHR48148:SF1 KERATINOCYTE PROLINE-RICH PROTEIN KERATINOCYTE PROLINE-RICH PROTEIN HUMAN|HGNC=4871|UniProtKB=Q9BVR0 Q9BVR0 HERC2P3 PTHR22870:SF398 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC2-RELATED guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=16156|UniProtKB=Q9BR09 Q9BR09 NEURL2 PTHR12429:SF8 NEURALIZED NEURALIZED-LIKE PROTEIN 2 ubiquitin-protein ligase#PC00234 Notch signaling pathway#P00045>Neuralized#P01117 HUMAN|HGNC=21590|UniProtKB=Q7Z5A8 Q7Z5A8 TAFA3 PTHR31770:SF3 CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER CHEMOKINE-LIKE PROTEIN TAFA-3 receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 negative regulation of biological process#GO:0048519;cell division#GO:0051301;neurogenesis#GO:0022008;developmental process#GO:0032502;negative regulation of inflammatory response#GO:0050728;cell population proliferation#GO:0008283;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;inflammatory response#GO:0006954;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;regulation of immune system process#GO:0002682;defense response#GO:0006952;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;leukocyte activation#GO:0045321;cellular developmental process#GO:0048869;regulation of response to external stimulus#GO:0032101;regulation of multicellular organismal process#GO:0051239;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell population proliferation#GO:0042127;positive regulation of response to external stimulus#GO:0032103;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;positive regulation of inflammatory response#GO:0050729;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;regulation of inflammatory response#GO:0050727;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;response to stress#GO:0006950;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of defense response#GO:0031347;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;negative regulation of immune system process#GO:0002683;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;generation of neurons#GO:0048699;positive regulation of defense response#GO:0031349 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 chemokine#PC00074 HUMAN|HGNC=11322|UniProtKB=Q14714 Q14714 SSPN PTHR15260:SF1 SARCOSPAN SARCOSPAN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;sarcolemma#GO:0042383 HUMAN|HGNC=27990|UniProtKB=Q5H9J7 Q5H9J7 BEX5 PTHR19430:SF0 PROTEIN BEX1-RELATED PROTEIN BEX5 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=3379|UniProtKB=O43491 O43491 EPB41L2 PTHR23280:SF17 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Nicotine pharmacodynamics pathway#P06587>EPB41L2#P06598;Dopamine receptor mediated signaling pathway#P05912>EPB41L2#P05952;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 HUMAN|HGNC=33175|UniProtKB=Q5MJ10 Q5MJ10 SPANXN2 PTHR23425:SF15 NUCLEOPORIN AMO1-LIKE SPERM PROTEIN ASSOCIATED WITH THE NUCLEUS ON THE X CHROMOSOME N2 HUMAN|HGNC=23914|UniProtKB=A6NDE4 A6NDE4 RBMY1B PTHR48034:SF17 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA-BINDING MOTIF PROTEIN, Y CHROMOSOME, FAMILY 1 MEMBER B positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;positive regulation of RNA metabolic process#GO:0051254;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=4712|UniProtKB=P51124 P51124 GZMM PTHR24271:SF51 KALLIKREIN-RELATED GRANZYME M serine protease#PC00203 HUMAN|HGNC=14133|UniProtKB=Q9NZV6 Q9NZV6 MSRB1 PTHR46755:SF5 METHIONINE-R-SULFOXIDE REDUCTASE B1 METHIONINE-R-SULFOXIDE REDUCTASE B1 reductase#PC00198 HUMAN|HGNC=5577|UniProtKB=P01814 P01814 IGHV2-70 PTHR23266:SF330 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-70-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=23370|UniProtKB=Q96H12 Q96H12 MSANTD3 PTHR21632:SF2 UNCHARACTERIZED MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 3 identical protein binding#GO:0042802;protein binding#GO:0005515;binding#GO:0005488 HUMAN|HGNC=19867|UniProtKB=Q9BXE9 Q9BXE9 VN1R3 PTHR24062:SF146 VOMERONASAL TYPE-1 RECEPTOR VOMERONASAL TYPE-1 RECEPTOR 3 transmembrane signal receptor#PC00197 HUMAN|HGNC=32695|UniProtKB=Q2VWA4 Q2VWA4 SKOR2 PTHR10005:SF7 SKI ONCOGENE-RELATED SKI FAMILY TRANSCRIPTIONAL COREPRESSOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;response to growth factor#GO:0070848;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=13090|UniProtKB=P17039 P17039 ZNF30 PTHR24377:SF826 IP01015P-RELATED ZINC FINGER PROTEIN 30 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=30348|UniProtKB=Q9NW08 Q9NW08 POLR3B PTHR20856:SF8 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;intracellular#GO:0005622;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;transferase complex#GO:1990234;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=20489|UniProtKB=Q96FK6 Q96FK6 WDR89 PTHR22889:SF0 UNCHARACTERIZED WD REPEAT-CONTAINING PROTEIN 89 HUMAN|HGNC=29813|UniProtKB=Q9H0E3 Q9H0E3 SAP130 PTHR13497:SF3 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=29396|UniProtKB=Q5R3F8 Q5R3F8 ELFN2 PTHR24373:SF263 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 29 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=23238|UniProtKB=Q9BPX1 Q9BPX1 HSD17B14 PTHR43658:SF13 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 17-BETA-HYDROXYSTEROID DEHYDROGENASE 14 oxidoreductase#PC00176 HUMAN|HGNC=15872|UniProtKB=Q8NHU2 Q8NHU2 CFAP61 PTHR21178:SF8 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61 structural protein#PC00211 HUMAN|HGNC=5295|UniProtKB=P28335 P28335 HTR2C PTHR24247:SF32 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2C cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=5585|UniProtKB=A0A0C4DH32 A0A0C4DH32 IGHV3-20 PTHR23266:SF248 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-20 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=19667|UniProtKB=Q8TBZ3 Q8TBZ3 WDR20 PTHR14107:SF5 WD REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 20 HUMAN|HGNC=18782|UniProtKB=Q16204 Q16204 CCDC6 PTHR15276:SF0 H4 D10S170 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 6 HUMAN|HGNC=7682|UniProtKB=O95803 O95803 NDST3 PTHR10605:SF29 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE/N-SULFOTRANSFERASE 3 sulfotransferase activity#GO:0008146;hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;heparan sulfate proteoglycan metabolic process#GO:0030201;proteoglycan biosynthetic process#GO:0030166;cellular carbohydrate metabolic process#GO:0044262;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;cellular polysaccharide biosynthetic process#GO:0033692;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transferase#PC00220 HUMAN|HGNC=484|UniProtKB=Q15389 Q15389 ANGPT1 PTHR19143:SF156 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-1 binding#GO:0005488;protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;enzyme linked receptor protein signaling pathway#GO:0007167;developmental process#GO:0032502;multicellular organism development#GO:0007275;tube development#GO:0035295;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;tube morphogenesis#GO:0035239;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Angiogenesis#P00005>Ang-1#P00248 HUMAN|HGNC=9102|UniProtKB=Q9HCM2 Q9HCM2 PLXNA4 PTHR22625:SF34 PLEXIN PLEXIN-A4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of GTPase activity#GO:0043087;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of neuron differentiation#GO:0045664;negative regulation of cell adhesion#GO:0007162;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;positive regulation of neuron projection development#GO:0010976;locomotion#GO:0040011;taxis#GO:0042330;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of cell projection organization#GO:0031346;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;biological adhesion#GO:0022610;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of cell adhesion#GO:0030155;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;positive regulation of neuron differentiation#GO:0045666;cellular response to stimulus#GO:0051716;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;cell migration#GO:0016477 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=1370|UniProtKB=O75493 O75493 CA11 PTHR18952:SF93 CARBONIC ANHYDRASE CARBONIC ANHYDRASE-RELATED PROTEIN 11 HUMAN|HGNC=29345|UniProtKB=Q9BY89 Q9BY89 KIAA1671 PTHR22042:SF3 TANKYRASE 1 BINDING PROTEIN TANKYRASE_BDG_C DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=26583|UniProtKB=Q5H9M0 Q5H9M0 PWWP3B PTHR31333:SF3 PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3 FAMILY MEMBER PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3B membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 DNA metabolism protein#PC00009 HUMAN|HGNC=28432|UniProtKB=Q8N5M4 Q8N5M4 TTC9C PTHR43811:SF1 FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA TETRATRICOPEPTIDE REPEAT PROTEIN 9C chaperone#PC00072 HUMAN|HGNC=3773|UniProtKB=P49326 P49326 FMO5 PTHR23023:SF78 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE 5 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 oxygenase#PC00177 HUMAN|HGNC=9608|UniProtKB=Q03431 Q03431 PTH1R PTHR45620:SF27 PDF RECEPTOR-LIKE PROTEIN-RELATED PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular cation homeostasis#GO:0030003;cellular response to stimulus#GO:0051716;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular ion homeostasis#GO:0006873;regulation of response to stimulus#GO:0048583;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=4374|UniProtKB=O60234 O60234 GMFG PTHR11249:SF4 GLIAL FACTOR NATURATION FACTOR GLIA MATURATION FACTOR GAMMA protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cortical patch#GO:0030479;organelle#GO:0043226;intracellular organelle#GO:0043229 intercellular signal molecule#PC00207 HUMAN|HGNC=8570|UniProtKB=Q9BY11 Q9BY11 PACSIN1 PTHR23065:SF16 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;dendrite development#GO:0016358;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;membrane invagination#GO:0010324;establishment of localization#GO:0051234;cytoskeleton organization#GO:0007010;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;regulation of endocytosis#GO:0030100;regulation of multicellular organismal process#GO:0051239;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;positive regulation of multicellular organismal process#GO:0051240;neurogenesis#GO:0022008;positive regulation of cell projection organization#GO:0031346;developmental process#GO:0032502;transport#GO:0006810;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;system development#GO:0048731;regulation of transport#GO:0051049;neuron differentiation#GO:0030182;vesicle organization#GO:0016050;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;positive regulation of neuron differentiation#GO:0045666;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;regulation of neurogenesis#GO:0050767;vesicle budding from membrane#GO:0006900;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 Huntington disease#P00029>PACSIN-1#P00802 HUMAN|HGNC=16935|UniProtKB=O95352 O95352 ATG7 PTHR10953:SF3 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7 ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;Atg12 activating enzyme activity#GO:0019778;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;nucleus organization#GO:0006997;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;lysosomal microautophagy#GO:0016237;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein lipidation#GO:0006497;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;C-terminal protein amino acid modification#GO:0018410;macromolecule biosynthetic process#GO:0009059;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;cellular response to stress#GO:0033554;piecemeal microautophagy of the nucleus#GO:0034727;autophagy of nucleus#GO:0044804;autophagy#GO:0006914 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;phagophore assembly site#GO:0000407;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 HUMAN|HGNC=26554|UniProtKB=Q96M29 Q96M29 TEKT5 PTHR19960:SF23 TEKTIN TEKTIN-5 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cilium movement involved in cell motility#GO:0060294;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;B axonemal microtubule#GO:0097650;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;nucleus#GO:0005634;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=7877|UniProtKB=A5YKK6 A5YKK6 CNOT1 PTHR13162:SF8 CCR4-NOT TRANSCRIPTION COMPLEX CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 molecular adaptor activity#GO:0060090;binding#GO:0005488 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cellular protein metabolic process#GO:0032269;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;intracellular#GO:0005622;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=2556|UniProtKB=Q93034 Q93034 CUL5 PTHR11932:SF76 CULLIN CULLIN-5 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=2496|UniProtKB=Q01459 Q01459 CTBS PTHR46290:SF1 FAMILY NOT NAMED DI-N-ACETYLCHITOBIASE HUMAN|HGNC=25126|UniProtKB=Q96HR8 Q96HR8 NAF1 PTHR31633:SF1 H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;ribonucleoprotein complex assembly#GO:0022618;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 small nucleolar ribonucleoprotein complex#GO:0005732;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26782|UniProtKB=Q6P656 Q6P656 CFAP161 PTHR24274:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161 structural protein#PC00211 HUMAN|HGNC=714|UniProtKB=P15848 P15848 ARSB PTHR10342:SF271 ARYLSULFATASE ARYLSULFATASE B HUMAN|HGNC=17793|UniProtKB=Q9UEU0 Q9UEU0 VTI1B PTHR21230:SF64 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;organelle fusion#GO:0048284;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;protein localization#GO:0008104;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;Golgi to vacuole transport#GO:0006896;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 HUMAN|HGNC=14068|UniProtKB=Q9UQL6 Q9UQL6 HDAC5 PTHR48252:SF50 HISTONE DEACETYLASE 2-RELATED HISTONE DEACETYLASE 5 HUMAN|HGNC=23494|UniProtKB=Q8IU99 Q8IU99 CALHM1 PTHR32261:SF2 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=6810|UniProtKB=O15480 O15480 MAGEB3 PTHR11736:SF53 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B3 scaffold/adaptor protein#PC00226 HUMAN|HGNC=16942|UniProtKB=Q76MJ5 Q76MJ5 ERN2 PTHR13954:SF15 IRE1-RELATED SERINE/THREONINE-PROTEIN KINASE/ENDORIBONUCLEASE IRE2 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;unfolded protein binding#GO:0051082;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to unfolded protein#GO:0034620;response to unfolded protein#GO:0006986;response to topologically incorrect protein#GO:0035966;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;signaling#GO:0023052 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 endoribonuclease#PC00094 Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110;Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125 HUMAN|HGNC=32554|UniProtKB=A6ND36 A6ND36 FAM83G PTHR16181:SF5 UNCHARACTERIZED PROTEIN FAM83G response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;response to BMP#GO:0071772;signaling#GO:0023052 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28746|UniProtKB=Q8IVP5 Q8IVP5 FUNDC1 PTHR21346:SF2 FUN14 DOMAIN CONTAINING FUN14 DOMAIN-CONTAINING PROTEIN 1 process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;mitochondrion organization#GO:0007005;cellular process#GO:0009987;organelle disassembly#GO:1903008;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;integral component of mitochondrial outer membrane#GO:0031307 HUMAN|HGNC=8485|UniProtKB=Q6IF36 Q6IF36 OR8G2P PTHR48018:SF27 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8G2-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=14261|UniProtKB=Q9NS28 Q9NS28 RGS18 PTHR10845:SF155 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 18 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 HUMAN|HGNC=19863|UniProtKB=Q8IZM9 Q8IZM9 SLC38A6 PTHR22950:SF366 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 6-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 amino acid transporter#PC00046 HUMAN|HGNC=7037|UniProtKB=P08582 P08582 MELTF PTHR11485:SF21 TRANSFERRIN MELANOTRANSFERRIN localization#GO:0051179;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;cation transport#GO:0006812 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;early endosome#GO:0005769;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 HUMAN|HGNC=10573|UniProtKB=O95171 O95171 SCEL PTHR15468:SF7 ZNF185 SCIELLIN epidermis development#GO:0008544;tissue development#GO:0009888;anatomical structure development#GO:0048856;developmental process#GO:0032502 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=13415|UniProtKB=Q6P2M8 Q6P2M8 PNCK PTHR24347:SF246 SERINE/THREONINE-PROTEIN KINASE CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1B non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=28909|UniProtKB=O60826 O60826 CCDC22 PTHR15668:SF4 JM1 PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 22 protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cellular catabolic process#GO:0031331;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;regulation of cellular protein catabolic process#GO:1903362;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cellular catabolic process#GO:0031329;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of protein catabolic process#GO:0045732;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=24891|UniProtKB=Q5TAQ9 Q5TAQ9 DCAF8 PTHR15574:SF57 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 8 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=20652|UniProtKB=Q96J42 Q96J42 TXNDC15 PTHR14684:SF2 UNCHARACTERIZED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=21680|UniProtKB=Q9H0K1 Q9H0K1 SIK2 PTHR24343:SF154 SERINE/THREONINE KINASE SERINE/THREONINE-PROTEIN KINASE SIK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=5046|UniProtKB=P52272 P52272 HNRNPM PTHR23003:SF6 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN M RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;response to oxidative stress#GO:0006979;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;response to stress#GO:0006950;regulation of cellular process#GO:0050794;nucleobase-containing compound catabolic process#GO:0034655;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;alternative mRNA splicing, via spliceosome#GO:0000380;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007;RNA splicing, via transesterification reactions#GO:0000375;cellular macromolecule catabolic process#GO:0044265 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=9175|UniProtKB=P28340 P28340 POLD1 PTHR10322:SF23 DNA POLYMERASE CATALYTIC SUBUNIT DNA POLYMERASE DELTA CATALYTIC SUBUNIT DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 HUMAN|HGNC=19373|UniProtKB=Q53FA7 Q53FA7 TP53I3 PTHR48106:SF8 QUINONE OXIDOREDUCTASE PIG3-RELATED QUINONE OXIDOREDUCTASE PIG3 oxidoreductase#PC00176 Huntington disease#P00029>PIG3#G01535 HUMAN|HGNC=23412|UniProtKB=Q5VSP4 Q5VSP4 LCN1P1 PTHR11430:SF127 LIPOCALIN LIPOCALIN 1-LIKE PROTEIN 1-RELATED binding#GO:0005488 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 HUMAN|HGNC=27414|UniProtKB=Q7Z6I6 Q7Z6I6 ARHGAP30 PTHR15729:SF12 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 30 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 GTPase-activating protein#PC00257 HUMAN|HGNC=26463|UniProtKB=Q96N06 Q96N06 SPATA33 PTHR38649:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 33 SPERMATOGENESIS-ASSOCIATED PROTEIN 33 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|Ensembl=ENSG00000231767|UniProtKB=A0A2R8Y422 A0A2R8Y422 RPS27AP5 PTHR10666:SF380 UBIQUITIN 40S RIBOSOMAL PROTEIN S27A enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=23323|UniProtKB=Q9H1U9 Q9H1U9 SLC25A51 PTHR46131:SF2 SD08549P SOLUTE CARRIER FAMILY 25 MEMBER 51-RELATED HUMAN|HGNC=30244|UniProtKB=Q6P1A2 Q6P1A2 LPCAT3 PTHR13906:SF14 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 5 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;organic substance biosynthetic process#GO:1901576;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;glycerophospholipid biosynthetic process#GO:0046474;organophosphate metabolic process#GO:0019637;phosphatidylcholine metabolic process#GO:0046470;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;membrane#GO:0016020 acetyltransferase#PC00038 HUMAN|HGNC=30092|UniProtKB=P43490 P43490 NAMPT PTHR43816:SF1 NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE transferase#PC00220 HUMAN|HGNC=2563|UniProtKB=O15482 O15482 TEX28 PTHR17613:SF10 CEREBRAL PROTEIN-11-RELATED TESTIS-SPECIFIC PROTEIN TEX28 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=16028|UniProtKB=O95760 O95760 IL33 PTHR21114:SF0 DVS27 PROTEIN INTERLEUKIN-33 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of gene expression#GO:0010628;gene expression#GO:0010467;inflammatory response#GO:0006954;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of cytokine production#GO:0001819;regulation of gene expression#GO:0010468;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;regulation of multicellular organismal process#GO:0051239;regulation of response to external stimulus#GO:0032101;macromolecule metabolic process#GO:0043170;positive regulation of response to external stimulus#GO:0032103;regulation of response to stress#GO:0080134;positive regulation of inflammatory response#GO:0050729;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of inflammatory response#GO:0050727;response to stress#GO:0006950;regulation of macromolecule metabolic process#GO:0060255;regulation of defense response#GO:0031347;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of defense response#GO:0031349;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240 HUMAN|HGNC=9385|UniProtKB=P54619 P54619 PRKAG1 PTHR13780:SF38 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;cation binding#GO:0043169;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;anion binding#GO:0043168;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;response to extracellular stimulus#GO:0009991;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular response to extracellular stimulus#GO:0031668;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;response to nutrient levels#GO:0031667;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830;p53 pathway by glucose deprivation#P04397>AMPK#P04639 HUMAN|HGNC=238|UniProtKB=P51828 P51828 ADCY7 PTHR45627:SF9 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 7 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Beta3 adrenergic receptor signaling pathway#P04379>AC#P04450;Opioid proopiomelanocortin pathway#P05917>AC#P06011;Dopamine receptor mediated signaling pathway#P05912>AC#P05947;GABA-B receptor II signaling#P05731>AC#P05760;5HT4 type receptor mediated signaling pathway#P04376>AC#P04429;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;5HT1 type receptor mediated signaling pathway#P04373>AC#P04406;Beta2 adrenergic receptor signaling pathway#P04378>AC#P04446;Enkephalin release#P05913>AC#P05978;Histamine H2 receptor mediated signaling pathway#P04386>AC#P04492;Opioid proenkephalin pathway#P05915>AC#P05993;Opioid prodynorphin pathway#P05916>AC#P06001;Beta1 adrenergic receptor signaling pathway#P04377>AC#P04439 HUMAN|HGNC=24612|UniProtKB=Q53F19 Q53F19 NCBP3 PTHR16291:SF0 NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3 NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25096|UniProtKB=Q9BU23 Q9BU23 LMF2 PTHR14463:SF5 LIPASE MATURATION FACTOR LIPASE MATURATION FACTOR 2 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;protein maturation#GO:0051604;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=24047|UniProtKB=Q8NHH9 Q8NHH9 ATL2 PTHR10751:SF42 GUANYLATE BINDING PROTEIN ATLASTIN-2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 heterotrimeric G-protein#PC00117 HUMAN|HGNC=25970|UniProtKB=Q8WVL7 Q8WVL7 ANKRD49 PTHR24144:SF5 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 49 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 49 HUMAN|HGNC=12117|UniProtKB=A0A0B4J274 A0A0B4J274 TRAV20 PTHR19433:SF114 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 20-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=12930|UniProtKB=Q05516 Q05516 ZBTB16 PTHR24393:SF60 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 16 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25161|UniProtKB=Q96EK2 Q96EK2 PHF21B PTHR24102:SF18 PHD FINGER PROTEIN PHD FINGER PROTEIN 21B HUMAN|HGNC=10776|UniProtKB=Q8N474 Q8N474 SFRP1 PTHR11309:SF87 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;non-canonical Wnt signaling pathway#GO:0035567;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>FRP#P00237;Wnt signaling pathway#P00057>sFRP#P01434 HUMAN|HGNC=11758|UniProtKB=Q92734 Q92734 TFG PTHR15335:SF7 PROTEIN TFG PROTEIN TFG localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=743|UniProtKB=P07307 P07307 ASGR2 PTHR22802:SF433 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR 2 membrane traffic protein#PC00150 HUMAN|HGNC=11592|UniProtKB=O43435 O43435 TBX1 PTHR11267:SF104 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 specification of symmetry#GO:0009799;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;heart looping#GO:0001947;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;heart development#GO:0007507;embryonic heart tube development#GO:0035050;determination of heart left/right asymmetry#GO:0061371;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;determination of bilateral symmetry#GO:0009855;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;determination of left/right symmetry#GO:0007368;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;morphogenesis of an epithelium#GO:0002009;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=18049|UniProtKB=Q08AH1 Q08AH1 ACSM1 PTHR43605:SF5 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM1, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 HUMAN|HGNC=23000|UniProtKB=Q7Z402 Q7Z402 TMC7 PTHR23302:SF42 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 7 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215 HUMAN|Ensembl=ENSG00000281573|UniProtKB=A0A0G2JP20 A0A0G2JP20 PRAMEF9 PTHR14224:SF100 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 11-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=13554|UniProtKB=Q8NB49 Q8NB49 ATP11C PTHR24092:SF38 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE IG pyrophosphatase activity#GO:0016462;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=1511|UniProtKB=P55211 P55211 CASP9 PTHR10454:SF157 CASPASE CASPASE-9 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 signal transduction#GO:0007165;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 Apoptosis signaling pathway#P00006>Caspase 9#P00298;FAS signaling pathway#P00020>Caspase9#P00593;FAS signaling pathway#P00020>Pro-Caspase9#P00603;VEGF signaling pathway#P00056>Caspase9#P01410;Angiogenesis#P00005>Caspase 9#P00216;PI3 kinase pathway#P00048>Caspase-9#P01197 HUMAN|HGNC=7880|UniProtKB=O95628 O95628 CNOT4 PTHR12603:SF0 CCR4-NOT TRANSCRIPTION COMPLEX RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 CCR4-NOT complex#GO:0030014;protein-containing complex#GO:0032991;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=33821|UniProtKB=Q6NVU6 Q6NVU6 UFSP1 PTHR48153:SF3 UFM1-SPECIFIC PROTEASE 2 INACTIVE UFM1-SPECIFIC PROTEASE 1 HUMAN|HGNC=25084|UniProtKB=Q8NCL8 Q8NCL8 TMEM116 PTHR23112:SF0 G PROTEIN-COUPLED RECEPTOR 157-RELATED TRANSMEMBRANE PROTEIN 116 G-protein coupled receptor#PC00021 HUMAN|HGNC=17753|UniProtKB=P62079 P62079 TSPAN5 PTHR19282:SF63 TETRASPANIN TETRASPANIN-5 protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=28005|UniProtKB=Q2VPK5 Q2VPK5 CTU2 PTHR20882:SF14 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA processing factor#PC00147 HUMAN|HGNC=17582|UniProtKB=Q8WYB5 Q8WYB5 KAT6B PTHR10615:SF73 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT6B protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;histone H3 acetylation#GO:0043966;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;peptidyl-lysine acetylation#GO:0018394;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone acetyltransferase complex#GO:0000123;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 p53 pathway#P00059>CBP#P04623 HUMAN|HGNC=9099|UniProtKB=Q9UIW2 Q9UIW2 PLXNA1 PTHR22625:SF35 PLEXIN PLEXIN-A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of GTPase activity#GO:0043087;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of neuron differentiation#GO:0045664;negative regulation of cell adhesion#GO:0007162;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;positive regulation of neuron projection development#GO:0010976;locomotion#GO:0040011;taxis#GO:0042330;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of cell projection organization#GO:0031346;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;biological adhesion#GO:0022610;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of cell adhesion#GO:0030155;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;chemotaxis#GO:0006935;positive regulation of neuron differentiation#GO:0045666;cellular response to stimulus#GO:0051716;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;cell migration#GO:0016477 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 Axon guidance mediated by semaphorins#P00007>PlexinA1#P00334 HUMAN|HGNC=18351|UniProtKB=B8ZZ34 B8ZZ34 SHISA8 PTHR31774:SF14 PROTEIN SHISA-9-RELATED PROTEIN SHISA-8 signal transduction#GO:0007165;regulation of neurotransmitter receptor activity#GO:0099601;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;ionotropic glutamate receptor signaling pathway#GO:0035235;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of AMPA receptor activity#GO:2000311;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;ion transmembrane transport#GO:0034220;regulation of synaptic plasticity#GO:0048167;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of signaling receptor activity#GO:0010469;response to stimulus#GO:0050896;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of trans-synaptic signaling#GO:0099177 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;leading edge membrane#GO:0031256;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;ion channel complex#GO:0034702;cell junction#GO:0030054;cell projection membrane#GO:0031253;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 HUMAN|HGNC=16075|UniProtKB=Q9H082 Q9H082 RAB33B PTHR47978:SF32 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33B endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=4020|UniProtKB=Q9Y231 Q9Y231 FUT9 PTHR11929:SF10 ALPHA- 1,3 -FUCOSYLTRANSFERASE 4-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 3-ALPHA-L-FUCOSYLTRANSFERASE 9 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111 HUMAN|HGNC=4861|UniProtKB=Q9NRZ9 Q9NRZ9 HELLS PTHR47161:SF1 LYMPHOID-SPECIFIC HELICASE LYMPHOID-SPECIFIC HELICASE chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;cell population proliferation#GO:0008283;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;leukocyte activation#GO:0045321;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cell activation#GO:0001775;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;macromolecule methylation#GO:0043414;heterochromatin organization#GO:0070828;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;lymphocyte activation#GO:0046649;heterochromatin assembly#GO:0031507;cellular biosynthetic process#GO:0044249;lymphocyte proliferation#GO:0046651;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;DNA conformation change#GO:0071103;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;intracellular#GO:0005622;chromosome, centromeric region#GO:0000775;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=24774|UniProtKB=A8MV23 A8MV23 SERPINE3 PTHR11461:SF129 SERINE PROTEASE INHIBITOR, SERPIN SERPIN E3 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=9935|UniProtKB=Q14257 Q14257 RCN2 PTHR10827:SF78 RETICULOCALBIN RETICULOCALBIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 calmodulin-related#PC00061 HUMAN|HGNC=17869|UniProtKB=Q9UHB7 Q9UHB7 AFF4 PTHR10528:SF15 AF4/FMR2 FAMILY MEMBER AF4/FMR2 FAMILY MEMBER 4 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023 DNA-binding transcription factor#PC00218 HUMAN|HGNC=19254|UniProtKB=Q9NZF1 Q9NZF1 PLAC8 PTHR15907:SF32 DUF614 FAMILY PROTEIN-RELATED PLACENTA-SPECIFIC GENE 8 PROTEIN positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 HUMAN|HGNC=16001|UniProtKB=Q9HAC7 Q9HAC7 SUGCT PTHR48207:SF3 SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE transferase#PC00220 Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864;Carnitine metabolism#P02733>Carnitine dehydratase#P02866 HUMAN|HGNC=23994|UniProtKB=Q8IV48 Q8IV48 ERI1 PTHR23044:SF71 3'-5' EXONUCLEASE ERI1-RELATED 3'-5' EXORIBONUCLEASE 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;RNA processing#GO:0006396;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;catabolic process#GO:0009056;ribosome biogenesis#GO:0042254;organic substance catabolic process#GO:1901575;maturation of 5.8S rRNA#GO:0000460;cleavage involved in rRNA processing#GO:0000469;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;DNA metabolic process#GO:0006259 exoribonuclease#PC00099 HUMAN|HGNC=28121|UniProtKB=Q5JSZ5 Q5JSZ5 PRRC2B PTHR14038:SF4 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 PROTEIN PRRC2B cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 RNA metabolism protein#PC00031 HUMAN|HGNC=30208|UniProtKB=Q96RQ1 Q96RQ1 ERGIC2 PTHR10984:SF30 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 2 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=25876|UniProtKB=Q8IV13 Q8IV13 CCNJL PTHR10177:SF63 CYCLINS CYCLIN-J-LIKE PROTEIN cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 HUMAN|HGNC=28706|UniProtKB=Q96NU1 Q96NU1 SAMD11 PTHR12247:SF67 POLYCOMB GROUP PROTEIN STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 11 protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=6148|UniProtKB=P20701 P20701 ITGAL PTHR23220:SF84 INTEGRIN ALPHA INTEGRIN ALPHA-L integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 HUMAN|HGNC=573|UniProtKB=Q9UPM8 Q9UPM8 AP4E1 PTHR22780:SF13 ADAPTIN, ALPHA/GAMMA/EPSILON AP-4 COMPLEX SUBUNIT EPSILON-1 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cellular anatomical entity#GO:0110165;membrane#GO:0016020;AP-type membrane coat adaptor complex#GO:0030119 membrane traffic protein#PC00150 HUMAN|HGNC=28107|UniProtKB=Q96CD2 Q96CD2 PPCDC PTHR14359:SF6 HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 decarboxylase#PC00089 Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882;Coenzyme A biosynthesis#P02736>Pantothenoylcysteine decarboxylase#P02883 HUMAN|HGNC=19241|UniProtKB=Q96K78 Q96K78 ADGRG7 PTHR12011:SF305 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G-PROTEIN COUPLED RECEPTOR G7 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=15311|UniProtKB=Q8NGG1 Q8NGG1 OR8J2 PTHR48018:SF131 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8J2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=6481|UniProtKB=P25391 P25391 LAMA1 PTHR10574:SF409 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA-1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;neuron differentiation#GO:0030182;vasculature development#GO:0001944;visual system development#GO:0150063;sensory system development#GO:0048880;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;cell morphogenesis involved in differentiation#GO:0000904;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;tube development#GO:0035295;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;eye development#GO:0001654;animal organ morphogenesis#GO:0009887;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;camera-type eye development#GO:0043010;generation of neurons#GO:0048699;sensory organ development#GO:0007423;locomotion#GO:0040011;taxis#GO:0042330 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=10612|UniProtKB=Q16627 Q16627 CCL14 PTHR12015:SF110 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 14 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=1789|UniProtKB=P42773 P42773 CDKN2C PTHR24201:SF9 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN CYCLIN-DEPENDENT KINASE 4 INHIBITOR C HUMAN|HGNC=3356|UniProtKB=P22413 P22413 ENPP1 PTHR10151:SF77 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 1 pyrophosphatase activity#GO:0016462;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;nucleotide diphosphatase activity#GO:0004551;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;exonuclease activity#GO:0004527;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 nucleoside triphosphate metabolic process#GO:0009141;fat cell differentiation#GO:0045444;heterocycle catabolic process#GO:0046700;nucleobase-containing compound metabolic process#GO:0006139;bone mineralization#GO:0030282;regulation of biological process#GO:0050789;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;anion transport#GO:0006820;nucleoside phosphate metabolic process#GO:0006753;biomineral tissue development#GO:0031214;regulation of ossification#GO:0030278;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;nucleoside phosphate catabolic process#GO:1901292;ossification#GO:0001503;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organophosphate catabolic process#GO:0046434;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;animal organ development#GO:0048513;developmental process#GO:0032502;transport#GO:0006810;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;cell differentiation#GO:0030154;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;inorganic anion transport#GO:0015698;cellular catabolic process#GO:0044248;biomineralization#GO:0110148;heterocycle metabolic process#GO:0046483;multicellular organism development#GO:0007275;ion transport#GO:0006811;nucleoside triphosphate catabolic process#GO:0009143;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;tissue development#GO:0009888;localization#GO:0051179;aromatic compound catabolic process#GO:0019439;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing small molecule metabolic process#GO:0055086 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|HGNC=15973|UniProtKB=Q86UW9 Q86UW9 DTX2 PTHR12622:SF21 DELTEX-RELATED E3 UBIQUITIN-PROTEIN LIGASE DTX2-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;Notch signaling pathway#GO:0007219 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=29418|UniProtKB=Q8TF40 Q8TF40 FNIP1 PTHR21634:SF12 UNCHARACTERIZED FOLLICULIN-INTERACTING PROTEIN 1 pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme inhibitor activity#GO:0004857;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234;chaperone binding#GO:0051087;ATPase activity#GO:0016887 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=32790|UniProtKB=Q9NRX1 Q9NRX1 PNO1 PTHR12826:SF13 RIBONUCLEASE Y RNA-BINDING PROTEIN PNO1 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14239|UniProtKB=Q9BYW1 Q9BYW1 SLC2A11 PTHR23503:SF22 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 11 HUMAN|HGNC=10669|UniProtKB=Q6ZSZ6 Q6ZSZ6 TSHZ1 PTHR12487:SF6 TEASHIRT-RELATED TEASHIRT HOMOLOG 1 binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=637|UniProtKB=P55087 P55087 AQP4 PTHR19139:SF34 AQUAPORIN TRANSPORTER AQUAPORIN-4 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 intrinsic component of membrane#GO:0031224;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=1005|UniProtKB=Q9BQE9 Q9BQE9 BCL7B PTHR12767:SF5 BCL7 RELATED B-CELL CLL/LYMPHOMA 7 PROTEIN FAMILY MEMBER B HUMAN|HGNC=9569|UniProtKB=Q9UL46 Q9UL46 PSME2 PTHR10660:SF6 PROTEASOME REGULATOR PA28 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 2 protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;enzyme activator activity#GO:0008047;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;proteasomal protein catabolic process#GO:0010498;regulation of G1/S transition of mitotic cell cycle#GO:2000045;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;cell cycle phase transition#GO:0044770;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;mitotic cell cycle phase transition#GO:0044772;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;positive regulation of catalytic activity#GO:0043085;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of mitotic cell cycle#GO:0007346 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Cell cycle#P00013>Proteasome#P00480 HUMAN|HGNC=25064|UniProtKB=Q0VFZ6 Q0VFZ6 CCDC173 PTHR28663:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 173 COILED-COIL DOMAIN-CONTAINING PROTEIN 173 HUMAN|HGNC=2917|UniProtKB=Q92988 Q92988 DLX4 PTHR24327:SF21 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=20452|UniProtKB=Q9Y5U4 Q9Y5U4 INSIG2 PTHR15301:SF10 INSULIN-INDUCED GENE 1 INSULIN-INDUCED GENE 2 PROTEIN positive regulation of gene expression#GO:0010628;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;steroid metabolic process#GO:0008202;cellular response to hormone stimulus#GO:0032870;negative regulation of cell communication#GO:0010648;protein localization to endoplasmic reticulum#GO:0070972;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cell communication#GO:0007154;alcohol metabolic process#GO:0006066;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;maintenance of location#GO:0051235;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;small molecule biosynthetic process#GO:0044283;steroid biosynthetic process#GO:0006694;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;response to peptide hormone#GO:0043434;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;response to lipid#GO:0033993;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;cellular response to lipid#GO:0071396;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to organic cyclic compound#GO:0071407;protein localization to organelle#GO:0033365;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;organic cyclic compound biosynthetic process#GO:1901362;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;maintenance of location in cell#GO:0051651;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;sterol biosynthetic process#GO:0016126;sterol metabolic process#GO:0016125;cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;alcohol biosynthetic process#GO:0046165;cholesterol biosynthetic process#GO:0006695;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;cholesterol metabolic process#GO:0008203;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular response to stress#GO:0080135;transcription, DNA-templated#GO:0006351;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;secondary alcohol biosynthetic process#GO:1902653;secondary alcohol metabolic process#GO:1902652;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;RNA biosynthetic process#GO:0032774;response to organonitrogen compound#GO:0010243;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;response to organic cyclic compound#GO:0014070;macromolecule localization#GO:0033036;response to insulin#GO:0032868;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to nitrogen compound#GO:1901699;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular macromolecule biosynthetic process#GO:0034645;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;integral component of membrane#GO:0016021;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;intrinsic component of endoplasmic reticulum membrane#GO:0031227;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=13030|UniProtKB=Q99592 Q99592 ZBTB18 PTHR24394:SF18 ZINC FINGER PROTEIN ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 18 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=8336|UniProtKB=A0A2R8Y4L6 A0A2R8Y4L6 OR5D3P PTHR48018:SF170 OLFACTORY RECEPTOR OLFACTORY RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=51715|UniProtKB=A0A096LPI5 A0A096LPI5 CCDC28A-AS1 PTHR12138:SF123 PRIMATE-EXPANDED PROTEIN FAMILY SUBFAMILY NOT NAMED HUMAN|HGNC=21898|UniProtKB=Q96SK2 Q96SK2 TMEM209 PTHR21780:SF0 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 209 HUMAN|HGNC=13174|UniProtKB=A6NK75 A6NK75 ZNF98 PTHR24384:SF108 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 492-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=1681|UniProtKB=P16070 P16070 CD44 PTHR10225:SF6 HYALURONAN RECEPTOR CD44 ANTIGEN carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;small molecule binding#GO:0036094;binding#GO:0005488;cytokine binding#GO:0019955;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;protein binding#GO:0005515;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;glycosaminoglycan binding#GO:0005539;transmembrane signaling receptor activity#GO:0004888 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cell adhesion#GO:0007155;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;biological adhesion#GO:0022610;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;inflammatory response#GO:0006954;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;ERK1 and ERK2 cascade#GO:0070371;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 receptor complex#GO:0043235;protein-containing complex#GO:0032991;basolateral plasma membrane#GO:0016323;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>CD44 intracellular fragment#P00121;Alzheimer disease-presenilin pathway#P00004>CD44 N-terminal fragment#P00174;Alzheimer disease-presenilin pathway#P00004>CD44#P00145;Alzheimer disease-presenilin pathway#P00004>CD44 C-terminal fragment#P00123;Alzheimer disease-presenilin pathway#P00004>CD44 transmembrane fragment#P00167 HUMAN|HGNC=20636|UniProtKB=Q09FC8 Q09FC8 ZNF415 PTHR24377:SF649 IP01015P-RELATED ZINC FINGER PROTEIN 415-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18990|UniProtKB=Q5T601 Q5T601 ADGRF1 PTHR45813:SF3 FAMILY NOT NAMED ADHESION G-PROTEIN COUPLED RECEPTOR F1 HUMAN|HGNC=27972|UniProtKB=Q86YV6 Q86YV6 MYLK4 PTHR24347:SF379 SERINE/THREONINE-PROTEIN KINASE MYOSIN LIGHT CHAIN KINASE FAMILY MEMBER 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 HUMAN|Ensembl=ENSG00000283463|UniProtKB=A0A1B0GTS1 A0A1B0GTS1 HSFX4 PTHR10015:SF140 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK TRANSCRIPTION FACTOR, X-LINKED MEMBER 3-RELATED winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=14099|UniProtKB=Q9ULM6 Q9ULM6 CNOT6 PTHR12121:SF33 CARBON CATABOLITE REPRESSOR PROTEIN 4 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=1616|UniProtKB=P49368 P49368 CCT3 PTHR11353:SF24 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT GAMMA protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;chaperone complex#GO:0101031;cellular anatomical entity#GO:0110165;chaperonin-containing T-complex#GO:0005832;intracellular#GO:0005622 chaperonin#PC00073 HUMAN|HGNC=7733|UniProtKB=Q14511 Q14511 NEDD9 PTHR10654:SF20 CAS SCAFFOLDING PROTEIN ENHANCER OF FILAMENTATION 1 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;actin cytoskeleton reorganization#GO:0031532;enzyme linked receptor protein signaling pathway#GO:0007167;localization of cell#GO:0051674;cell motility#GO:0048870;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 HUMAN|HGNC=16707|UniProtKB=Q96T75 Q96T75 DSCR8 PTHR12138:SF74 PRIMATE-EXPANDED PROTEIN FAMILY DOWN SYNDROME CRITICAL REGION PROTEIN 8 HUMAN|HGNC=30452|UniProtKB=A1XBS5 A1XBS5 FAM92A PTHR21223:SF4 UNCHARACTERIZED PROTEIN FAM92A HUMAN|HGNC=8554|UniProtKB=P11940 P11940 PABPC1 PTHR24012:SF409 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=18554|UniProtKB=Q9BZM1 Q9BZM1 PLA2G12A PTHR12824:SF7 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GROUP XIIA SECRETORY PHOSPHOLIPASE A2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase A2 activity#GO:0004623;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 phospholipase#PC00186 HUMAN|HGNC=17106|UniProtKB=Q8NFU0 Q8NFU0 BEST4 PTHR10736:SF3 BESTROPHIN BESTROPHIN-4 ion channel#PC00133 HUMAN|HGNC=16406|UniProtKB=Q5JVL4 Q5JVL4 EFHC1 PTHR12086:SF9 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cell division#GO:0051301;mitotic spindle organization#GO:0007052;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;spindle organization#GO:0007051;cytokinesis#GO:0000910;membrane fission#GO:0090148;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;cilium movement#GO:0003341;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;movement of cell or subcellular component#GO:0006928;organelle fission#GO:0048285;cell cycle#GO:0007049;locomotion#GO:0040011 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 calmodulin-related#PC00061 HUMAN|HGNC=6974|UniProtKB=O15151 O15151 MDM4 PTHR13844:SF20 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D PROTEIN MDM4 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway#P00059>Mdm2#P01483;P53 pathway feedback loops 1#P04392>MDM-2#G04682;p53 pathway feedback loops 2#P04398>Mdm2#P04663;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#P04496;P53 pathway feedback loops 1#P04392>Mdm2#P04536;p53 pathway feedback loops 2#P04398>MDM-2#G04709;p53 pathway#P00059>MDM-2#G01563;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#G04674 HUMAN|HGNC=3467|UniProtKB=P03372 P03372 ESR1 PTHR48092:SF16 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=3234|UniProtKB=Q9H1U4 Q9H1U4 MEGF9 PTHR10574:SF298 NETRIN/LAMININ-RELATED MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 9 system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;tissue development#GO:0009888 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=8821|UniProtKB=Q5T2W1 Q5T2W1 PDZK1 PTHR14191:SF6 PDZ DOMAIN CONTAINING PROTEIN NA(+)/H(+) EXCHANGE REGULATORY COFACTOR NHE-RF3-RELATED molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 HUMAN|HGNC=34438|UniProtKB=Q4G0S7 Q4G0S7 CCDC152 PTHR35253:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 152 COILED-COIL DOMAIN-CONTAINING PROTEIN 152 HUMAN|HGNC=29241|UniProtKB=Q9H0H0 Q9H0H0 INTS2 PTHR28608:SF1 INTEGRATOR COMPLEX SUBUNIT 2 INTEGRATOR COMPLEX SUBUNIT 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 HUMAN|HGNC=4054|UniProtKB=P09912 P09912 IFI6 PTHR16932:SF25 INTERFERON ALPHA-INDUCIBLE PROTEIN 27 INTERFERON ALPHA-INDUCIBLE PROTEIN 6 regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;regulation of apoptotic signaling pathway#GO:2001233;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;negative regulation of apoptotic signaling pathway#GO:2001234;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;negative regulation of endopeptidase activity#GO:0010951;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043154;negative regulation of signal transduction#GO:0009968;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of hydrolase activity#GO:0051346;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;ion homeostasis#GO:0050801;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;regulation of membrane potential#GO:0042391;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11927|UniProtKB=O43508 O43508 TNFSF12 PTHR15151:SF20 PROTEIN EIGER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 12 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;lymphocyte mediated immunity#GO:0002449;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;production of molecular mediator of immune response#GO:0002440;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;nitrogen compound metabolic process#GO:0006807;somatic diversification of immune receptors via germline recombination within a single locus#GO:0002562;positive regulation of immune effector process#GO:0002699;B cell activation#GO:0042113;regulation of adaptive immune response#GO:0002819;somatic diversification of immune receptors#GO:0002200;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;B cell activation involved in immune response#GO:0002312;organic substance metabolic process#GO:0071704;lymphocyte activation involved in immune response#GO:0002285;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;regulation of immune response#GO:0050776;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;positive regulation of lymphocyte mediated immunity#GO:0002708;DNA recombination#GO:0006310;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;leukocyte activation involved in immune response#GO:0002366;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of production of molecular mediator of immune response#GO:0002700;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of adaptive immune response#GO:0002821;regulation of multicellular organismal development#GO:2000026;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;somatic recombination of immunoglobulin gene segments#GO:0016447;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;somatic cell DNA recombination#GO:0016444;positive regulation of leukocyte mediated immunity#GO:0002705;positive regulation of immunoglobulin mediated immune response#GO:0002891;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of lymphocyte activation#GO:0051249;immune effector process#GO:0002252;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;immunoglobulin production#GO:0002377;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;multicellular organism development#GO:0007275;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;regulation of immune effector process#GO:0002697;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of leukocyte activation#GO:0002694;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;positive regulation of immunoglobulin production#GO:0002639;regulation of DNA recombination#GO:0000018;DNA metabolic process#GO:0006259 cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extracellular region#GO:0005576;plasma membrane#GO:0005886 HUMAN|HGNC=30955|UniProtKB=Q96SQ5 Q96SQ5 ZNF587 PTHR24377:SF655 IP01015P-RELATED ZINC FINGER PROTEIN 417-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18070|UniProtKB=Q8WUX1 Q8WUX1 SLC38A5 PTHR22950:SF74 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 5 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 amino acid transporter#PC00046 HUMAN|HGNC=6444|UniProtKB=P04259 P04259 KRT6B PTHR45616:SF39 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 6A-RELATED HUMAN|HGNC=4601|UniProtKB=P28799 P28799 GRN PTHR12274:SF3 GRANULIN PROGRANULIN cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=13556|UniProtKB=Q9HBG6 Q9HBG6 IFT122 PTHR12764:SF4 WD REPEAT DOMAIN-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG vesicle targeting, to, from or within Golgi#GO:0048199;non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;intraciliary retrograde transport#GO:0035721;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 non-motile cilium#GO:0097730;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=35121|UniProtKB=A6NGY3 A6NGY3 C5orf52 PTHR35666:SF1 SIMILAR TO RIKEN CDNA 4921536K21 SIMILAR TO RIKEN CDNA 4921536K21 HUMAN|HGNC=21177|UniProtKB=Q8IYT3 Q8IYT3 CCDC170 PTHR18863:SF4 TSEC-2-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 170 HUMAN|HGNC=33764|UniProtKB=Q6ZRT6 Q6ZRT6 PRR23B PTHR31813:SF18 PROLINE-RICH PROTEIN 23B PROLINE-RICH PROTEIN 23B HUMAN|HGNC=23573|UniProtKB=Q9Y6X9 Q9Y6X9 MORC2 PTHR23337:SF7 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1 ATPASE MORC2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=6990|UniProtKB=P51608 P51608 MECP2 PTHR15074:SF6 METHYL-CPG-BINDING PROTEIN METHYL-CPG-BINDING PROTEIN 2 sequence-specific DNA binding#GO:0043565;nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=24527|UniProtKB=A5PLN7 A5PLN7 FAM149A PTHR31997:SF2 AGAP003710-PA PROTEIN FAM149A HUMAN|HGNC=16466|UniProtKB=Q9UMX1 Q9UMX1 SUFU PTHR10928:SF2 SUPPRESSOR OF FUSED SUPPRESSOR OF FUSED HOMOLOG protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of molecular function#GO:0065009;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;maintenance of location#GO:0051235;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of DNA-binding transcription factor activity#GO:0043433;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 Hedgehog signaling pathway#P00025>Su(fu)#P00699 HUMAN|HGNC=3561|UniProtKB=P51161 P51161 FABP6 PTHR11955:SF69 FATTY ACID BINDING PROTEIN GASTROTROPIN HUMAN|HGNC=11429|UniProtKB=O75558 O75558 STX11 PTHR19957:SF30 SYNTAXIN SYNTAXIN-11 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;vesicle organization#GO:0016050;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;export from cell#GO:0140352 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 HUMAN|HGNC=29990|UniProtKB=O60356 O60356 NUPR1 PTHR17149:SF5 NUCLEAR PROTEIN 1 AND 2 NUCLEAR PROTEIN 1 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell population proliferation#GO:0042127;negative regulation of cell cycle#GO:0045786;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;negative regulation of cell population proliferation#GO:0008285;cellular process#GO:0009987;cell population proliferation#GO:0008283;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=28507|UniProtKB=Q8NHP7 Q8NHP7 EXD1 PTHR46628:SF1 PIRNA BIOGENESIS PROTEIN EXD1 PIRNA BIOGENESIS PROTEIN EXD1 HUMAN|HGNC=20164|UniProtKB=Q8IX15 Q8IX15 HOMEZ PTHR15467:SF7 ZINC-FINGERS AND HOMEOBOXES RELATED HOMEOBOX AND LEUCINE ZIPPER PROTEIN HOMEZ sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=11551|UniProtKB=Q92994 Q92994 BRF1 PTHR11618:SF4 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 HUMAN|HGNC=18286|UniProtKB=Q96IS3 Q96IS3 RAX2 PTHR46271:SF2 HOMEOBOX PROTEIN, PUTATIVE-RELATED RETINA AND ANTERIOR NEURAL FOLD HOMEOBOX PROTEIN 2 homeodomain transcription factor#PC00119 HUMAN|HGNC=5106|UniProtKB=P20719 P20719 HOXA5 PTHR45659:SF10 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=26649|UniProtKB=Q6UWD8 Q6UWD8 C16orf54 PTHR36134:SF1 TRANSMEMBRANE PROTEIN C16ORF54 TRANSMEMBRANE PROTEIN C16ORF54 HUMAN|HGNC=20488|UniProtKB=Q96EM0 Q96EM0 L3HYPDH PTHR33442:SF1 TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE dehydratase#PC00091 HUMAN|HGNC=17101|UniProtKB=Q15022 Q15022 SUZ12 PTHR22597:SF0 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SUZ12 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=8009|UniProtKB=Q9P2S2 Q9P2S2 NRXN2 PTHR15036:SF52 PIKACHURIN-LIKE PROTEIN NEUREXIN-2 HUMAN|HGNC=4532|UniProtKB=Q9BXC0 Q9BXC0 HCAR1 PTHR46048:SF3 HYDROXYCARBOXYLIC ACID RECEPTOR 2 HYDROXYCARBOXYLIC ACID RECEPTOR 1 HUMAN|HGNC=3093|UniProtKB=Q92630 Q92630 DYRK2 PTHR24058:SF51 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;peptidyl-threonine phosphorylation#GO:0018107;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=24241|UniProtKB=Q6P1Q0 Q6P1Q0 LETMD1 PTHR14009:SF13 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN LETM1 DOMAIN-CONTAINING PROTEIN 1 cellular chemical homeostasis#GO:0055082;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;metal ion homeostasis#GO:0055065;cellular ion homeostasis#GO:0006873 secondary carrier transporter#PC00258 HUMAN|HGNC=1764|UniProtKB=P33151 P33151 CDH5 PTHR24027:SF89 CADHERIN-23 CADHERIN-5 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 establishment or maintenance of cell polarity#GO:0007163;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;circulatory system development#GO:0072359;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;establishment of cell polarity#GO:0030010;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;vasculature development#GO:0001944;cell junction assembly#GO:0034329 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;bicellular tight junction#GO:0005923;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical junction complex#GO:0043296;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=24102|UniProtKB=Q96EG1 Q96EG1 ARSG PTHR42693:SF33 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE G-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=3695|UniProtKB=Q08830 Q08830 FGL1 PTHR19143:SF263 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN-LIKE PROTEIN 1 negative regulation of biological process#GO:0048519;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;regulation of T cell activation#GO:0050863;leukocyte cell-cell adhesion#GO:0007159;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;leukocyte activation#GO:0045321;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;negative regulation of T cell activation#GO:0050868;lymphocyte activation#GO:0046649;immune response#GO:0006955;regulation of immune response#GO:0050776;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;regulation of response to stimulus#GO:0048583;cell activation#GO:0001775;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of lymphocyte activation#GO:0051250 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=17906|UniProtKB=Q9BQ39 Q9BQ39 DDX50 PTHR47958:SF88 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX50 pyrophosphatase activity#GO:0016462;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11578|UniProtKB=Q86TI0 Q86TI0 TBC1D1 PTHR22957:SF204 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 1 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=29146|UniProtKB=A2VDJ0 A2VDJ0 TMEM131L PTHR22050:SF2 RW1 PROTEIN HOMOLOG TRANSMEMBRANE PROTEIN 131-LIKE cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=17284|UniProtKB=Q9NUX5 Q9NUX5 POT1 PTHR14513:SF0 PROTECTION OF TELOMERES 1 PROTECTION OF TELOMERES PROTEIN 1 nucleic acid binding#GO:0003676;RNA-directed DNA polymerase activity#GO:0003964;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme inhibitor activity#GO:0004857;telomerase activity#GO:0003720;enzyme regulator activity#GO:0030234;sequence-specific DNA binding#GO:0043565;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 telomere maintenance via telomere lengthening#GO:0010833;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;telomere-telomerase complex assembly#GO:1905324;regulation of biological process#GO:0050789;regulation of telomere maintenance via telomerase#GO:0032210;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;negative regulation of DNA metabolic process#GO:0051053;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;telomere capping#GO:0016233;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;RNA-dependent DNA biosynthetic process#GO:0006278;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;telomere organization#GO:0032200;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;telomere maintenance via telomerase#GO:0007004;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transferase activity#GO:0051348;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of telomere maintenance via telomere lengthening#GO:1904356;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of molecular function#GO:0044092;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;nuclear telomere cap complex#GO:0000783;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781;protein-DNA complex#GO:0032993;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=14398|UniProtKB=Q9GZT4 Q9GZT4 SRR PTHR43050:SF1 SERINE / THREONINE RACEMASE FAMILY MEMBER SERINE RACEMASE carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;magnesium ion binding#GO:0000287;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;isomerase activity#GO:0016853;cation binding#GO:0043169;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;ATP binding#GO:0005524 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 epimerase/racemase#PC00096 Isoleucine biosynthesis#P02748>Threonine dehydratase#P02995 HUMAN|HGNC=24075|UniProtKB=Q86WK7 Q86WK7 AMIGO3 PTHR24368:SF62 AMPHOTERIN-INDUCED PROTEIN AMPHOTERIN-INDUCED PROTEIN 3 head development#GO:0060322;system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;brain development#GO:0007420;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417;nervous system development#GO:0007399 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=27418|UniProtKB=A6NCS6 A6NCS6 C2orf72 PTHR35675:SF1 HYPOTHETICAL PROTEIN LOC100362216 HYPOTHETICAL PROTEIN LOC100362216 HUMAN|HGNC=30269|UniProtKB=Q96E17 Q96E17 RAB3C PTHR47980:SF15 LD44762P RAS-RELATED PROTEIN RAB-3C vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;protein secretion#GO:0009306;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 Synaptic vesicle trafficking#P05734>Rab3A#P05780 HUMAN|HGNC=4083|UniProtKB=P28472 P28472 GABRB3 PTHR18945:SF571 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;system process#GO:0003008;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=29565|UniProtKB=Q86YN1 Q86YN1 DOLPP1 PTHR11247:SF40 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 DOLICHYLDIPHOSPHATASE 1 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=389|UniProtKB=O43488 O43488 AKR7A2 PTHR43625:SF12 AFLATOXIN B1 ALDEHYDE REDUCTASE AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 2 reductase#PC00198 HUMAN|HGNC=2342|UniProtKB=P43155 P43155 CRAT PTHR22589:SF50 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYLTRANSFERASE transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=3507|UniProtKB=Q03828 Q03828 EVX2 PTHR46294:SF1 SEGMENTATION PROTEIN EVEN-SKIPPED HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16777|UniProtKB=Q9BYS1 Q9BYS1 KRTAP1-5 PTHR23262:SF195 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 1-5 HUMAN|HGNC=14840|UniProtKB=Q8NGM9 Q8NGM9 OR8D4 PTHR48018:SF137 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8D4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=10586|UniProtKB=Q07699 Q07699 SCN1B PTHR10546:SF2 SODIUM CHANNEL SUBUNIT BETA-1 AND 3 SODIUM CHANNEL SUBUNIT BETA-1 blood circulation#GO:0008015;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;heart contraction#GO:0060047;regulation of membrane potential#GO:0042391;cardiac muscle contraction#GO:0060048;system process#GO:0003008;action potential#GO:0001508;regulation of system process#GO:0044057;cellular process#GO:0009987;circulatory system process#GO:0003013;actin-mediated cell contraction#GO:0070252;striated muscle contraction#GO:0006941;regulation of biological process#GO:0050789;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;signaling#GO:0023052;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 voltage-gated ion channel#PC00241 HUMAN|HGNC=11644|UniProtKB=Q15906 Q15906 VPS72 PTHR13275:SF4 YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG protein-DNA complex subunit organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;histone exchange#GO:0043486;nucleosome organization#GO:0034728;organelle organization#GO:0006996;chromosome organization#GO:0051276;ATP-dependent chromatin remodeling#GO:0043044;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;protein-containing complex subunit organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=24885|UniProtKB=Q4ZG55 Q4ZG55 GREB1 PTHR15720:SF13 GREB1-RELATED PROTEIN GREB1 HUMAN|HGNC=22210|UniProtKB=Q9ULK2 Q9ULK2 ATXN7L1 PTHR15117:SF9 ATAXIN 7 RELATED ATAXIN-7-LIKE PROTEIN 1 HUMAN|HGNC=27252|UniProtKB=Q7Z2G1 Q7Z2G1 H2BW1 PTHR23428:SF254 HISTONE H2B HISTONE H2B TYPE W-T nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=7894|UniProtKB=Q99742 Q99742 NPAS1 PTHR23043:SF25 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA NEURONAL PAS DOMAIN-CONTAINING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=5014|UniProtKB=P30519 P30519 HMOX2 PTHR10720:SF2 HEME OXYGENASE HEME OXYGENASE 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 cellular aromatic compound metabolic process#GO:0006725;inorganic ion homeostasis#GO:0098771;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;porphyrin-containing compound metabolic process#GO:0006778;response to oxidative stress#GO:0006979;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;iron ion homeostasis#GO:0055072;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;heme metabolic process#GO:0042168;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;heterocycle metabolic process#GO:0046483;transition metal ion homeostasis#GO:0055076;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;pigment metabolic process#GO:0042440;cation homeostasis#GO:0055080;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;chemical homeostasis#GO:0048878;response to stimulus#GO:0050896;response to stress#GO:0006950;aromatic compound catabolic process#GO:0019439;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;metal ion homeostasis#GO:0055065 oxygenase#PC00177 HUMAN|HGNC=5953|UniProtKB=O95976 O95976 IGSF6 PTHR15297:SF2 IMMUNOGLOBULIN SUPERFAMILY MEMBER 6 IMMUNOGLOBULIN SUPERFAMILY MEMBER 6 immunoglobulin#PC00123 HUMAN|HGNC=15141|UniProtKB=Q8NGQ3 Q8NGQ3 OR1S2 PTHR48001:SF115 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1S1-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=1858|UniProtKB=Q7Z7A1 Q7Z7A1 CNTRL PTHR34491:SF2 A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED CENTRIOLIN HUMAN|HGNC=25391|UniProtKB=Q7Z2Y5 Q7Z2Y5 NRK PTHR48015:SF1 SERINE/THREONINE-PROTEIN KINASE TAO NIK-RELATED PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;actin cytoskeleton reorganization#GO:0031532;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;actin cytoskeleton organization#GO:0030036;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=10004|UniProtKB=O75916 O75916 RGS9 PTHR45746:SF1 LP21163P REGULATOR OF G-PROTEIN SIGNALING 9 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>RGS9#P00749;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=8517|UniProtKB=Q9NRC9 Q9NRC9 OTOR PTHR47146:SF1 OTORAPLIN OTORAPLIN system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;connective tissue development#GO:0061448;cartilage development#GO:0051216;skeletal system development#GO:0001501;cellular process#GO:0009987;tissue development#GO:0009888 HUMAN|HGNC=19825|UniProtKB=Q6SA08 Q6SA08 TSSK4 PTHR24343:SF345 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE/THREONINE-PROTEIN KINASE 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=14971|UniProtKB=Q9UNH6 Q9UNH6 SNX7 PTHR45949:SF3 SORTING NEXIN-4 SORTING NEXIN-7 scaffold/adaptor protein#PC00226 HUMAN|HGNC=16499|UniProtKB=Q96DA2 Q96DA2 RAB39B PTHR47979:SF69 DRAB11-RELATED RAS-RELATED PROTEIN RAB-39B bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=30213|UniProtKB=Q9NQ11 Q9NQ11 ATP13A2 PTHR45630:SF2 CATION-TRANSPORTING ATPASE-RELATED POLYAMINE-TRANSPORTING ATPASE 13A2 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 HUMAN|HGNC=11498|UniProtKB=O43759 O43759 SYNGR1 PTHR10838:SF7 SYNAPTOGYRIN SYNAPTOGYRIN-1 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=2714|UniProtKB=O43602 O43602 DCX PTHR23005:SF4 RETINITIS PIGMENTOSA 1 PROTEIN NEURONAL MIGRATION PROTEIN DOUBLECORTIN-RELATED microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;sensory system development#GO:0048880;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;anatomical structure development#GO:0048856;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;animal organ development#GO:0048513;developmental process#GO:0032502;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;retina development in camera-type eye#GO:0060041;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;protein localization to organelle#GO:0033365;visual system development#GO:0150063;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cell development#GO:0048468;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;eye development#GO:0001654;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;camera-type eye development#GO:0043010;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=23293|UniProtKB=Q7Z5K2 Q7Z5K2 WAPL PTHR22100:SF13 WINGS APART-LIKE PROTEIN HOMOLOG WINGS APART-LIKE PROTEIN HOMOLOG cellular localization#GO:0051641;regulation of chromosome segregation#GO:0051983;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;nuclear division#GO:0000280;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;chromosome condensation#GO:0030261;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;sister chromatid cohesion#GO:0007062;regulation of molecular function#GO:0065009;meiotic cell cycle process#GO:1903046;reproductive process#GO:0022414;protein localization to organelle#GO:0033365;regulation of protein localization#GO:0032880;regulation of chromosome organization#GO:0033044;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;reproduction#GO:0000003;cellular macromolecule localization#GO:0070727;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;chromosome organization#GO:0051276;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045 HUMAN|HGNC=2972|UniProtKB=Q05193 Q05193 DNM1 PTHR11566:SF32 DYNAMIN DYNAMIN-1 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;membrane organization#GO:0061024;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;membrane fission#GO:0090148;vesicle localization#GO:0051648;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;protein transport#GO:0015031;biological regulation#GO:0065007;protein polymerization#GO:0051258;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;regulation of synapse structure or activity#GO:0050803;mitochondrial fission#GO:0000266;vesicle-mediated transport in synapse#GO:0099003;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;non-membrane-bounded organelle#GO:0043228;membrane coat#GO:0030117;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;mitochondrial envelope#GO:0005740;plasma membrane region#GO:0098590;postsynapse#GO:0098794;coated membrane#GO:0048475;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;envelope#GO:0031975;membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;mitochondrial membrane#GO:0031966;intracellular vesicle#GO:0097708;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;mitochondrion#GO:0005739;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Gonadotropin-releasing hormone receptor pathway#P06664>Dnm1#P06781;CCKR signaling map#P06959>Dynamin#P07100 HUMAN|HGNC=3321|UniProtKB=P19419 P19419 ELK1 PTHR11849:SF178 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 Interleukin signaling pathway#P00036>ELK#P00962;Gonadotropin-releasing hormone receptor pathway#P06664>ELK1#P06785;p38 MAPK pathway#P05918>ELK#P06013;PDGF signaling pathway#P00047>ELK#P01140;Ras Pathway#P04393>Elk-1#P04573;Oxidative stress response#P00046>Elk-1#P01136;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ELK#P00890;CCKR signaling map#P06959>ELK1#P07146;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>ELK1#P05934;Toll receptor signaling pathway#P00054>Elk1#P01341;Parkinson disease#P00049>Elk-1#P01233 HUMAN|HGNC=7719|UniProtKB=P56181 P56181 NDUFV3 PTHR17117:SF1 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 3, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=28633|UniProtKB=Q8N5I2 Q8N5I2 ARRDC1 PTHR11188:SF163 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN DOMAIN-CONTAINING PROTEIN 1 amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;protein transport#GO:0015031;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=29120|UniProtKB=O94889 O94889 KLHL18 PTHR24412:SF210 KELCH PROTEIN KELCH-LIKE PROTEIN 18 scaffold/adaptor protein#PC00226 HUMAN|HGNC=34347|UniProtKB=A6NL82 A6NL82 FAM183A PTHR33865:SF2 PROTEIN FAM183B PROTEIN FAM183A ciliary transition fiber#GO:0097539;protein-containing complex#GO:0032991;ciliary base#GO:0097546;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 HUMAN|HGNC=18637|UniProtKB=Q9H853 Q9H853 TUBA4B PTHR11588:SF442 TUBULIN TUBULIN-LIKE PROTEIN ALPHA-4B-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 HUMAN|HGNC=17537|UniProtKB=Q9NY37 Q9NY37 ASIC5 PTHR11690:SF272 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 5 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=37257|UniProtKB=Q8WVI0 Q8WVI0 SMIM4 PTHR35250:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 4 SMALL INTEGRAL MEMBRANE PROTEIN 4 HUMAN|HGNC=11588|UniProtKB=P20226 P20226 TBP PTHR10126:SF20 TATA-BOX BINDING PROTEIN TATA-BOX-BINDING PROTEIN transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;RNA polymerase II general transcription initiation factor activity#GO:0016251 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 Huntington disease#P00029>TBP#P00779;General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 HUMAN|HGNC=3025|UniProtKB=P21917 P21917 DRD4 PTHR24247:SF205 5-HYDROXYTRYPTAMINE RECEPTOR D(4) DOPAMINE RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Nicotine pharmacodynamics pathway#P06587>DRD2/ DRD3/ DRD4#P06603;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D2/D3/D4#P05965 HUMAN|HGNC=15139|UniProtKB=Q8NGF6 Q8NGF6 OR10W1 PTHR26452:SF165 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10W1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=2210|UniProtKB=P05997 P05997 COL5A2 PTHR24023:SF539 COLLAGEN ALPHA COLLAGEN ALPHA-2(V) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;extracellular region#GO:0005576;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=2710|UniProtKB=P32321 P32321 DCTD PTHR11086:SF18 DEOXYCYTIDYLATE DEAMINASE-RELATED DEOXYCYTIDYLATE DEAMINASE deaminase#PC00088 HUMAN|HGNC=19696|UniProtKB=Q9HAV7 Q9HAV7 GRPEL1 PTHR21237:SF25 GRPE PROTEIN GRPE PROTEIN HOMOLOG 1, MITOCHONDRIAL nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068 HUMAN|HGNC=15620|UniProtKB=Q96LC7 Q96LC7 SIGLEC10 PTHR12035:SF115 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 10 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=3809|UniProtKB=Q12946 Q12946 FOXF1 PTHR46262:SF1 FORKHEAD BOX PROTEIN BINIOU FORKHEAD BOX PROTEIN F1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=812|UniProtKB=P16615 P16615 ATP2A2 PTHR42861:SF18 CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 2 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 bounding membrane of organelle#GO:0098588;sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;sarcoplasmic reticulum membrane#GO:0033017;sarcoplasm#GO:0016528;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=13061|UniProtKB=Q14587 Q14587 ZNF268 PTHR24376:SF199 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 268 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1407|UniProtKB=O60359 O60359 CACNG3 PTHR12107:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-3 SUBUNIT calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;cation channel activity#GO:0005261;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 cellular localization#GO:0051641;membrane organization#GO:0061024;system process#GO:0003008;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;anterograde trans-synaptic signaling#GO:0098916;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;regulation of transmembrane transporter activity#GO:0022898;positive regulation of signaling#GO:0023056;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;establishment of protein localization to vacuole#GO:0072666;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;protein localization to synapse#GO:0035418;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of ion transmembrane transport#GO:0034765;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein localization to cell junction#GO:1902414;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;regulation of trans-synaptic signaling#GO:0099177;regulation of ion transport#GO:0043269;multicellular organismal process#GO:0032501;protein-containing complex localization#GO:0031503;receptor localization to synapse#GO:0097120;signal transduction#GO:0007165;regulation of neurotransmitter receptor activity#GO:0099601;receptor internalization#GO:0031623;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;action potential#GO:0001508;cation transport#GO:0006812;ionotropic glutamate receptor signaling pathway#GO:0035235;cation transmembrane transport#GO:0098655;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;vacuolar transport#GO:0007034;protein localization to membrane#GO:0072657;regulation of membrane potential#GO:0042391;protein localization to vacuole#GO:0072665;ion transport#GO:0006811;establishment of protein localization to organelle#GO:0072594;regulation of AMPA receptor activity#GO:2000311;nervous system process#GO:0050877;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;protein localization to cell periphery#GO:1990778;localization#GO:0051179;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of synaptic transmission#GO:0050806;synaptic transmission, glutamatergic#GO:0035249 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;organelle#GO:0043226;integral component of membrane#GO:0016021;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=14291|UniProtKB=Q8N2Q7 Q8N2Q7 NLGN1 PTHR43903:SF2 NEUROLIGIN NEUROLIGIN-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;transport#GO:0006810;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;vesicle organization#GO:0016050;cell junction assembly#GO:0034329;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;endocytosis#GO:0006897;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;vesicle budding from membrane#GO:0006900;synapse assembly#GO:0007416;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;vesicle-mediated transport in synapse#GO:0099003 cell surface#GO:0009986;synapse#GO:0045202;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;cell junction#GO:0030054;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=14088|UniProtKB=Q9UGC6 Q9UGC6 RGS17 PTHR10845:SF196 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 17 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 HUMAN|HGNC=7788|UniProtKB=Q14938 Q14938 NFIX PTHR11492:SF3 NUCLEAR FACTOR I NUCLEAR FACTOR 1 X-TYPE cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=17197|UniProtKB=Q96LW1 Q96LW1 ZNF354B PTHR24377:SF641 IP01015P-RELATED ZINC FINGER PROTEIN 354B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2064|UniProtKB=O95833 O95833 CLIC3 PTHR43920:SF3 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL PROTEIN 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ion channel#PC00133 HUMAN|HGNC=6112|UniProtKB=P51617 P51617 IRAK1 PTHR24419:SF1 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;response to interleukin-1#GO:0070555;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;regulation of gene expression#GO:0010468;cytokine-mediated signaling pathway#GO:0019221;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 Toll receptor signaling pathway#P00054>IRAK1#P01343 HUMAN|HGNC=27363|UniProtKB=Q6ZRS4 Q6ZRS4 ITPRID1 PTHR17469:SF14 SPERM SPECIFIC ANTIGEN 2-RELATED PROTEIN ITPRID1 HUMAN|HGNC=18899|UniProtKB=Q9BYR2 Q9BYR2 KRTAP4-5 PTHR23262:SF71 KERATIN ASSOCIATED PROTEIN HCG2042993-RELATED HUMAN|HGNC=25792|UniProtKB=Q9BQ65 Q9BQ65 USB1 PTHR13522:SF3 UNCHARACTERIZED U6 SNRNA PHOSPHODIESTERASE catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=77|UniProtKB=P42684 P42684 ABL2 PTHR24418:SF87 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL2 regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=3528|UniProtKB=P00742 P00742 F10 PTHR24278:SF28 COAGULATION FACTOR COAGULATION FACTOR X extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>FX#P00430;Blood coagulation#P00011>FXa#P00445 HUMAN|HGNC=14530|UniProtKB=Q3SY56 Q3SY56 SP6 PTHR23235:SF23 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15570|UniProtKB=Q6UW49 Q6UW49 SPESP1 PTHR31667:SF2 SPERM EQUATORIAL SEGMENT PROTEIN 1 SPERM EQUATORIAL SEGMENT PROTEIN 1 plasma membrane fusion#GO:0045026;fertilization#GO:0009566;membrane organization#GO:0061024;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;cellular component organization#GO:0016043;cellular process#GO:0009987;multi-organism process#GO:0051704;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;membrane fusion#GO:0061025;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;acrosome reaction#GO:0007340 acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=29938|UniProtKB=Q8WUQ7 Q8WUQ7 CACTIN PTHR21737:SF6 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 CACTIN response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;defense response#GO:0006952;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;regulation of response to stress#GO:0080134;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of defense response#GO:0031347;biological regulation#GO:0065007;mRNA processing#GO:0006397;negative regulation of response to external stimulus#GO:0032102;negative regulation of immune system process#GO:0002683;RNA splicing, via transesterification reactions#GO:0000375;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20451|UniProtKB=Q8IWB7 Q8IWB7 WDFY1 PTHR46189:SF2 LD41958P WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=6427|UniProtKB=Q04695 Q04695 KRT17 PTHR23239:SF180 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 17 HUMAN|HGNC=15302|UniProtKB=Q8NGQ2 Q8NGQ2 OR6Q1 PTHR26453:SF140 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6Q1 transmembrane signal receptor#PC00197 HUMAN|HGNC=1840|UniProtKB=Q9BXF3 Q9BXF3 CECR2 PTHR47092:SF1 CAT EYE SYNDROME CRITICAL REGION PROTEIN 2 CAT EYE SYNDROME CRITICAL REGION PROTEIN 2 HUMAN|HGNC=19134|UniProtKB=Q8IZP7 Q8IZP7 HS6ST3 PTHR12812:SF3 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE 3 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;heparan sulfate proteoglycan metabolic process#GO:0030201;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=4984|UniProtKB=P05114 P05114 HMGN1 PTHR23087:SF12 NONHISTONE CHROMOSOMAL PROTEIN HMG NON-HISTONE CHROMOSOMAL PROTEIN HMG-14 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=24682|UniProtKB=Q9Y5Y0 Q9Y5Y0 FLVCR1 PTHR10924:SF2 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED FELINE LEUKEMIA VIRUS SUBGROUP C RECEPTOR-RELATED PROTEIN 1-RELATED tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heme binding#GO:0020037 myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;metal ion transport#GO:0030001;immune system development#GO:0002520;animal organ development#GO:0048513;ion transport#GO:0006811;transport#GO:0006810;developmental process#GO:0032502;multicellular organism development#GO:0007275;hematopoietic or lymphoid organ development#GO:0048534;nitrogen compound transport#GO:0071705;homeostatic process#GO:0042592;cation transport#GO:0006812;cellular process#GO:0009987;erythrocyte differentiation#GO:0030218;localization#GO:0051179;mitochondrial transport#GO:0006839;immune system process#GO:0002376;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anatomical structure development#GO:0048856;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258 HUMAN|HGNC=23444|UniProtKB=Q5VXJ0 Q5VXJ0 LIPK PTHR11005:SF45 LYSOSOMAL ACID LIPASE-RELATED LIPASE MEMBER K membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 lipase#PC00143 HUMAN|HGNC=4508|UniProtKB=Q9Y2T5 Q9Y2T5 GPR52 PTHR24240:SF181 OPSIN G-PROTEIN COUPLED RECEPTOR 52 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to abiotic stimulus#GO:0071214;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=4944|UniProtKB=P01920 P01920 HLA-DQB1 PTHR19944:SF101 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ BETA 1 CHAIN major histocompatibility complex protein#PC00149 HUMAN|HGNC=16962|UniProtKB=Q99674 Q99674 CGREF1 PTHR23104:SF11 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN CELL GROWTH REGULATOR WITH EF HAND DOMAIN PROTEIN 1 membrane traffic protein#PC00150 HUMAN|HGNC=16648|UniProtKB=Q8NG27 Q8NG27 PJA1 PTHR15710:SF2 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE PRAJA-1 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=16049|UniProtKB=Q15185 Q15185 PTGES3 PTHR22932:SF3 TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE PROSTAGLANDIN E SYNTHASE 3 heat shock protein binding#GO:0031072;protein binding#GO:0005515;isomerase activity#GO:0016853;chaperone binding#GO:0051087;binding#GO:0005488;catalytic activity#GO:0003824;Hsp90 protein binding#GO:0051879 telomere maintenance via telomere lengthening#GO:0010833;cellular component biogenesis#GO:0044085;ribonucleoprotein complex subunit organization#GO:0071826;icosanoid biosynthetic process#GO:0046456;protein-DNA complex assembly#GO:0065004;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;telomere-telomerase complex assembly#GO:1905324;carboxylic acid biosynthetic process#GO:0046394;prostaglandin metabolic process#GO:0006693;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;monocarboxylic acid biosynthetic process#GO:0072330;macromolecule metabolic process#GO:0043170;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;organic acid metabolic process#GO:0006082;fatty acid derivative metabolic process#GO:1901568;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;RNA-dependent DNA biosynthetic process#GO:0006278;nucleobase-containing compound biosynthetic process#GO:0034654;unsaturated fatty acid metabolic process#GO:0033559;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;unsaturated fatty acid biosynthetic process#GO:0006636;telomere maintenance via telomerase#GO:0007004;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;fatty acid biosynthetic process#GO:0006633;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;fatty acid metabolic process#GO:0006631;protein folding#GO:0006457;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=53615|UniProtKB=P0DPD8 P0DPD8 EEF1AKMT4-ECE2 PTHR11733:SF127 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED EEF1AKMT4-ECE2 READTHROUGH TRANSCRIPT PROTEIN-RELATED metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 HUMAN|HGNC=33894|UniProtKB=B2RU33 B2RU33 POTEC PTHR24118:SF65 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER B-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=656|UniProtKB=P49703 P49703 ARL4D PTHR11711:SF137 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4D carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 HUMAN|HGNC=24869|UniProtKB=Q9H3Q3 Q9H3Q3 GAL3ST2 PTHR14647:SF55 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSE-3-O-SULFOTRANSFERASE 2 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=18260|UniProtKB=Q9NX57 Q9NX57 RAB20 PTHR24073:SF941 DRAB5-RELATED RAS-RELATED PROTEIN RAB-20 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=16856|UniProtKB=Q14674 Q14674 ESPL1 PTHR12792:SF0 EXTRA SPINDLE POLES 1-RELATED SEPARIN cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;chromosome segregation#GO:0007059;meiotic chromosome separation#GO:0051307;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic cell cycle process#GO:1903046;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;reproductive process#GO:0022414;cell cycle#GO:0007049;organelle fission#GO:0048285 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819 cysteine protease#PC00081 HUMAN|HGNC=13145|UniProtKB=P51815 P51815 ZNF75D PTHR23226:SF272 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 75D cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=16836|UniProtKB=Q8WUH2 Q8WUH2 TGFBRAP1 PTHR12894:SF27 CNH DOMAIN CONTAINING TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;catabolic process#GO:0009056;vesicle organization#GO:0016050;autophagy#GO:0006914;organelle fusion#GO:0048284;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=26522|UniProtKB=Q96MB7 Q96MB7 HARBI1 PTHR22930:SF227 UNCHARACTERIZED NUCLEASE HARBI1-RELATED HUMAN|HGNC=28948|UniProtKB=Q5BJD5 Q5BJD5 TMEM41B PTHR43220:SF18 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41B HUMAN|HGNC=26350|UniProtKB=Q7Z5J8 Q7Z5J8 ANKAR PTHR46464:SF1 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN AND ARMADILLO REPEAT-CONTAINING PROTEIN HUMAN|HGNC=28086|UniProtKB=Q8N183 Q8N183 NDUFAF2 PTHR32470:SF2 ADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2 oxidation-reduction process#GO:0055114;cellular respiration#GO:0045333;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 chaperone#PC00072 HUMAN|HGNC=21460|UniProtKB=Q8TD10 Q8TD10 MIPOL1 PTHR22089:SF2 MIRROR-IMAGE POLYDACTYLY GENE 1 PROTEIN MIRROR-IMAGE POLYDACTYLY GENE 1 PROTEIN HUMAN|HGNC=26857|UniProtKB=Q7Z745 Q7Z745 MROH2B PTHR23120:SF22 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 2B HUMAN|HGNC=685|UniProtKB=Q15052 Q15052 ARHGEF6 PTHR46026:SF2 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=5998|UniProtKB=Q01638 Q01638 IL1RL1 PTHR11890:SF7 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR-LIKE 1 transmembrane signal receptor#PC00197 HUMAN|HGNC=21684|UniProtKB=Q96JM2 Q96JM2 ZNF462 PTHR24403:SF58 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 462 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15987|UniProtKB=O76003 O76003 GLRX3 PTHR10293:SF16 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-3-RELATED reductase#PC00198 HUMAN|HGNC=39|UniProtKB=Q8IUA7 Q8IUA7 ABCA9 PTHR19229:SF120 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 9 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=6711|UniProtKB=Q06643 Q06643 LTB PTHR11471:SF29 TUMOR NECROSIS FACTOR FAMILY MEMBER LYMPHOTOXIN-BETA protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 Apoptosis signaling pathway#P00006>TNF#P00259 HUMAN|HGNC=1068|UniProtKB=O95972 O95972 BMP15 PTHR11848:SF22 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 15 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 Gonadotropin-releasing hormone receptor pathway#P06664>BMP2/4/15#P06817;TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=37453|UniProtKB=E5RHQ5 E5RHQ5 NPIPB11 PTHR15438:SF5 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER B11-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=21107|UniProtKB=Q5TB80 Q5TB80 CEP162 PTHR34031:SF1 CENTROSOMAL PROTEIN OF 162 KDA CENTROSOMAL PROTEIN OF 162 KDA HUMAN|HGNC=10334|UniProtKB=P62899 P62899 RPL31 PTHR10956:SF4 60S RIBOSOMAL PROTEIN L31 60S RIBOSOMAL PROTEIN L31 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=7138|UniProtKB=P55198 P55198 MLLT6 PTHR13793:SF90 PHD FINGER PROTEINS PROTEIN AF-17 nucleosome binding#GO:0031491;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=20867|UniProtKB=Q969V1 Q969V1 MCHR2 PTHR24230:SF7 G-PROTEIN COUPLED RECEPTOR MELANIN-CONCENTRATING HORMONE RECEPTOR 2 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=17208|UniProtKB=Q8TD16 Q8TD16 BICD2 PTHR31233:SF7 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D HOMOLOG 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of organelle organization#GO:0033043;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;microtubule anchoring#GO:0034453;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=20731|UniProtKB=Q9HAV0 Q9HAV0 GNB4 PTHR19850:SF28 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-4 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Wnt signaling pathway#P00057>GBeta#P01457;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;PI3 kinase pathway#P00048>Gbetagamma#P01188;GABA-B receptor II signaling#P05731>Gbeta#P05755;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753 HUMAN|HGNC=12863|UniProtKB=Q9Y6Q3 Q9Y6Q3 ZFP37 PTHR24381:SF147 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 37 HOMOLOG DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=12031|UniProtKB=Q13077 Q13077 TRAF1 PTHR10131:SF96 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 1 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625;tumor necrosis factor receptor binding#GO:0005164;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of MAPK cascade#GO:0043408;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;positive regulation of protein modification process#GO:0031401;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;stress-activated MAPK cascade#GO:0051403;cellular protein metabolic process#GO:0044267;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of DNA-binding transcription factor activity#GO:0051091;positive regulation of protein metabolic process#GO:0051247;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;transcription, DNA-templated#GO:0006351;regulation of JNK cascade#GO:0046328;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;JNK cascade#GO:0007254;positive regulation of signaling#GO:0023056;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;tumor necrosis factor-mediated signaling pathway#GO:0033209;RNA biosynthetic process#GO:0032774;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of stress-activated MAPK cascade#GO:0032874;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of stress-activated protein kinase signaling cascade#GO:0070302;cellular macromolecule biosynthetic process#GO:0034645;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of stress-activated MAPK cascade#GO:0032872;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;protein K63-linked ubiquitination#GO:0070534 membrane protein complex#GO:0098796;receptor complex#GO:0043235;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18021|UniProtKB=Q7Z403 Q7Z403 TMC6 PTHR23302:SF4 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN 6 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215 HUMAN|HGNC=18241|UniProtKB=Q96LA8 Q96LA8 PRMT6 PTHR11006:SF89 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 6 protein modifying enzyme#PC00260 HUMAN|HGNC=20115|UniProtKB=Q6Q0C1 Q6Q0C1 SLC25A47 PTHR45624:SF3 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 47 ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;organic substance transport#GO:0071702;quaternary ammonium group transport#GO:0015697;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic cation transport#GO:0015695;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812 transporter#PC00227 HUMAN|HGNC=6057|UniProtKB=Q16352 Q16352 INA PTHR45652:SF18 GLIAL FIBRILLARY ACIDIC PROTEIN ALPHA-INTERNEXIN HUMAN|HGNC=25296|UniProtKB=Q8IYM0 Q8IYM0 FAM186B PTHR33590:SF3 GLUTENIN, HIGH MOLECULAR WEIGHT SUBUNIT PW212-RELATED PROTEIN PROTEIN FAM186B HUMAN|HGNC=6455|UniProtKB=O76014 O76014 KRT37 PTHR23239:SF353 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA7 HUMAN|HGNC=3587|UniProtKB=Q9NPI8 Q9NPI8 FANCF PTHR14449:SF2 FANCONI ANEMIA GROUP F PROTEIN FANCF FANCONI ANEMIA GROUP F PROTEIN response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to DNA damage stimulus#GO:0006974;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stress#GO:0033554 membrane-enclosed lumen#GO:0031974;Fanconi anaemia nuclear complex#GO:0043240;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14853|UniProtKB=Q8NH53 Q8NH53 OR52N1 PTHR26450:SF145 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52N1 transmembrane signal receptor#PC00197 HUMAN|HGNC=16354|UniProtKB=Q8IWW8 Q8IWW8 ADHFE1 PTHR11496:SF83 ALCOHOL DEHYDROGENASE HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092 HUMAN|HGNC=20341|UniProtKB=Q8IZN3 Q8IZN3 ZDHHC14 PTHR22883:SF28 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC14-RELATED transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=21580|UniProtKB=Q5VV43 Q5VV43 KIAA0319 PTHR46182:SF1 FI19480P1 DYSLEXIA-ASSOCIATED PROTEIN KIAA0319 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=10768|UniProtKB=O75533 O75533 SF3B1 PTHR12097:SF0 SPLICING FACTOR 3B, SUBUNIT 1-RELATED SPLICING FACTOR 3B SUBUNIT 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;Prp19 complex#GO:0000974;U12-type spliceosomal complex#GO:0005689 RNA splicing factor#PC00148 HUMAN|HGNC=21057|UniProtKB=Q9H1X1 Q9H1X1 RSPH9 PTHR22069:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN S18 RADIAL SPOKE HEAD PROTEIN 9 HOMOLOG microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cilium movement involved in cell motility#GO:0060294;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 ribosomal protein#PC00202 HUMAN|HGNC=234|UniProtKB=O60266 O60266 ADCY3 PTHR45627:SF13 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 3 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 regulation of adenylate cyclase activity#GO:0045761;cyclic nucleotide metabolic process#GO:0009187;purine nucleotide biosynthetic process#GO:0006164;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;regulation of response to stimulus#GO:0048583;ribonucleotide biosynthetic process#GO:0009260;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cAMP-mediated signaling#GO:0019933;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;second-messenger-mediated signaling#GO:0019932;organophosphate biosynthetic process#GO:0090407;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;signaling#GO:0023052;metabolic process#GO:0008152;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;response to stimulus#GO:0050896;biological regulation#GO:0065007;nucleobase-containing small molecule metabolic process#GO:0055086;cyclic-nucleotide-mediated signaling#GO:0019935;purine ribonucleotide biosynthetic process#GO:0009152 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 HUMAN|HGNC=10897|UniProtKB=P12757 P12757 SKIL PTHR10005:SF3 SKI ONCOGENE-RELATED SKI-LIKE PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;nucleobase-containing compound metabolic process#GO:0006139;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;BMP signaling pathway#GO:0030509;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;negative regulation of signal transduction#GO:0009968;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;negative regulation of RNA metabolic process#GO:0051253;response to growth factor#GO:0070848;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of cellular response to transforming growth factor beta stimulus#GO:1903844;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;negative regulation of transforming growth factor beta receptor signaling pathway#GO:0030512;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Gonadotropin-releasing hormone receptor pathway#P06664>SKIL#P06858 HUMAN|HGNC=16133|UniProtKB=Q96BZ9 Q96BZ9 TBC1D20 PTHR20913:SF10 TBC1 DOMAIN FAMILY MEMBER 20/GTPASE TBC1 DOMAIN FAMILY MEMBER 20 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 GTPase-activating protein#PC00257 HUMAN|Ensembl=ENSG00000274243|UniProtKB=A0A0G2JLM5 A0A0G2JLM5 ENSG00000274243 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=24754|UniProtKB=P86496 P86496 PRR20A PTHR38819:SF1 PROLINE-RICH PROTEIN 20A-RELATED PROLINE-RICH PROTEIN 20A-RELATED HUMAN|HGNC=7593|UniProtKB=Q9HD67 Q9HD67 MYO10 PTHR46049:SF2 FAMILY NOT NAMED UNCONVENTIONAL MYOSIN-X Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=9649|UniProtKB=Q99952 Q99952 PTPN18 PTHR45983:SF4 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 18 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=10353|UniProtKB=P36578 P36578 RPL4 PTHR19431:SF5 60S RIBOSOMAL PROTEIN L4 60S RIBOSOMAL PROTEIN L4 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=28816|UniProtKB=Q7L592 Q7L592 NDUFAF7 PTHR12049:SF7 UNCHARACTERIZED PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 HUMAN|HGNC=3704|UniProtKB=Q13643 Q13643 FHL3 PTHR24205:SF5 FOUR AND A HALF LIM DOMAINS PROTEIN FOUR AND A HALF LIM DOMAINS PROTEIN 3 cytoskeletal protein binding#GO:0008092;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 transcription cofactor#PC00217 HUMAN|HGNC=2076|UniProtKB=O75503 O75503 CLN5 PTHR15380:SF2 CEROID-LIPOFUSCINOSIS, NEURONAL 5 CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 5 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824 lysosome organization#GO:0007040;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=9977|UniProtKB=O75677 O75677 RFPL1 PTHR25462:SF289 BONUS, ISOFORM C-RELATED RET FINGER PROTEIN-LIKE 1-RELATED HUMAN|HGNC=25332|UniProtKB=Q8NDD1 Q8NDD1 C1orf131 PTHR28366:SF1 UNCHARACTERIZED ZGC:194224 HUMAN|HGNC=11298|UniProtKB=Q9H3Y6 Q9H3Y6 SRMS PTHR24418:SF23 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRMS protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell population proliferation#GO:0008283;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;innate immune response#GO:0045087;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;peptidyl-tyrosine modification#GO:0018212;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 HUMAN|HGNC=8829|UniProtKB=Q9BRX2 Q9BRX2 PELO PTHR10853:SF0 PELOTA PROTEIN PELOTA HOMOLOG negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;rRNA metabolic process#GO:0016072;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation release factor#PC00225 HUMAN|HGNC=31960|UniProtKB=Q4V326 Q4V326 GAGE2E PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=7891|UniProtKB=Q9NPH5 Q9NPH5 NOX4 PTHR11972:SF182 NADPH OXIDASE NADPH OXIDASE 4 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;defense response#GO:0006952;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;oxidoreductase complex#GO:1990204;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175 HUMAN|HGNC=14446|UniProtKB=Q8TEW8 Q8TEW8 PARD3B PTHR16484:SF4 PARTITIONING DEFECTIVE 3 RELATED PARTITIONING DEFECTIVE 3 HOMOLOG B lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;biological adhesion#GO:0022610;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of cell polarity#GO:0030010;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;organelle organization#GO:0006996;centrosome localization#GO:0051642;establishment of localization in cell#GO:0051649;establishment or maintenance of apical/basal cell polarity#GO:0035088;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;establishment or maintenance of bipolar cell polarity#GO:0061245 cytoplasm#GO:0005737;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;cell junction#GO:0030054;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical junction complex#GO:0043296;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 HUMAN|HGNC=2292|UniProtKB=P15954 P15954 COX7C PTHR13313:SF1 CYTOCHROME C OXIDASE SUBUNIT VIIC CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;aerobic electron transport chain#GO:0019646;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 oxidase#PC00175 HUMAN|HGNC=14067|UniProtKB=Q8WUI4 Q8WUI4 HDAC7 PTHR48252:SF20 HISTONE DEACETYLASE 2-RELATED HISTONE DEACETYLASE 7 CCKR signaling map#P06959>HDAC7#P07235 HUMAN|Ensembl=ENSG00000248767|UniProtKB=A0A1W2PRP0 A0A1W2PRP0 FOXL3 PTHR11829:SF211 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=37175|UniProtKB=A6NCW0 A6NCW0 USP17L3 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=13150|UniProtKB=Q15935 Q15935 ZNF77 PTHR24381:SF361 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 77 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29816|UniProtKB=Q9UH90 Q9UH90 FBXO40 PTHR15933:SF1 PROTEIN CBG16327 F-BOX ONLY PROTEIN 40 HUMAN|HGNC=16060|UniProtKB=Q8WWH5 Q8WWH5 TRUB1 PTHR13767:SF2 TRNA-PSEUDOURIDINE SYNTHASE TRNA PSEUDOURIDINE SYNTHASE 1-RELATED isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 isomerase#PC00135 HUMAN|HGNC=3326|UniProtKB=P28324 P28324 ELK4 PTHR11849:SF21 ETS ETS DOMAIN-CONTAINING PROTEIN ELK-4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 Interleukin signaling pathway#P00036>ELK#P00962;CCKR signaling map#P06959>SAP1#P07097;PDGF signaling pathway#P00047>ELK#P01140 HUMAN|Ensembl=ENSG00000275306|UniProtKB=A0A0G2JQ47 A0A0G2JQ47 ENSG00000275306 PTHR11738:SF113 MHC CLASS I NK CELL RECEPTOR KIR2DL PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=10978|UniProtKB=Q8NFF2 Q8NFF2 SLC24A4 PTHR10846:SF21 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM/POTASSIUM/CALCIUM EXCHANGER 4 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;cation:cation antiporter activity#GO:0015491;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;solute:cation antiporter activity#GO:0015298;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=13450|UniProtKB=Q8N9N5 Q8N9N5 BANP PTHR16243:SF2 BTG3-ASSOCIATED NUCLEAR PROTEIN BANP PROTEIN BANP cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein catabolic process#GO:0042177;protein localization to nucleus#GO:0034504;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;negative regulation of catabolic process#GO:0009895;cellular macromolecule localization#GO:0070727;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 HUMAN|HGNC=9306|UniProtKB=Q9Y2T4 Q9Y2T4 PPP2R2C PTHR11871:SF5 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B GAMMA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629 HUMAN|HGNC=4498|UniProtKB=O14842 O14842 FFAR1 PTHR45822:SF4 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 1 HUMAN|HGNC=6351|UniProtKB=O95600 O95600 KLF8 PTHR23235:SF46 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 8 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26023|UniProtKB=Q8N9H8 Q8N9H8 EXD3 PTHR13620:SF96 3-5 EXONUCLEASE EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2-RELATED Lipoate_biosynthesis#P02750>Lipoyl-protein ligase#P03003 HUMAN|HGNC=9212|UniProtKB=P14859 P14859 POU2F1 PTHR11636:SF47 POU DOMAIN POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Gonadotropin-releasing hormone receptor pathway#P06664>OCT-1#P06720 HUMAN|HGNC=5931|UniProtKB=A0A075B6I0 A0A075B6I0 IGLV8-61 PTHR23267:SF176 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 8-61 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=11755|UniProtKB=P04155 P04155 TFF1 PTHR13826:SF18 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CCKR signaling map#P06959>TFF1#G06993;CCKR signaling map#P06959>TFF1#G07287 HUMAN|HGNC=2993|UniProtKB=Q9NYP3 Q9NYP3 DONSON PTHR12972:SF0 DOWNSTREAM NEIGHBOR OF SON PROTEIN DOWNSTREAM NEIGHBOR OF SON cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cell cycle DNA replication#GO:0044786;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;nuclear DNA replication#GO:0033260;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cell cycle#GO:0007049;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=20312|UniProtKB=Q86VN1 Q86VN1 VPS36 PTHR13128:SF12 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 protein catabolic process in the vacuole#GO:0007039;endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;multivesicular body sorting pathway#GO:0071985;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular macromolecule localization#GO:0070727;cellular protein catabolic process#GO:0044257;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=9716|UniProtKB=Q9NR77 Q9NR77 PXMP2 PTHR11266:SF114 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 PEROXISOMAL MEMBRANE PROTEIN 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=12456|UniProtKB=Q15695 Q15695 ZRSR2P1 PTHR12620:SF33 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR 35 KDA SUBUNIT-RELATED PROTEIN 1-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 mRNA splicing#P00058>U2AF65#P01475 HUMAN|HGNC=14836|UniProtKB=Q8NH81 Q8NH81 OR10G6 PTHR26453:SF179 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G6 transmembrane signal receptor#PC00197 HUMAN|HGNC=34228|UniProtKB=I1YAP6 I1YAP6 TRIM77 PTHR24103:SF567 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 77 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9141|UniProtKB=Q15126 Q15126 PMVK PTHR13101:SF1 PHOSPHOMEVALONATE KINASE PHOSPHOMEVALONATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 sterol metabolic process#GO:0016125;cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cholesterol biosynthetic process#GO:0006695;cholesterol metabolic process#GO:0008203;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;secondary alcohol biosynthetic process#GO:1902653;secondary alcohol metabolic process#GO:1902652;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;nucleotide metabolic process#GO:0009117;steroid biosynthetic process#GO:0006694;cellular amide metabolic process#GO:0043603;sterol biosynthetic process#GO:0016126;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 kinase#PC00137 Cholesterol biosynthesis#P00014>Phosphomevalonate kinase#P00500 HUMAN|HGNC=24668|UniProtKB=Q9BXR6 Q9BXR6 CFHR5 PTHR45785:SF9 COMPLEMENT FACTOR H-RELATED COMPLEMENT FACTOR H-RELATED PROTEIN 5 HUMAN|HGNC=18865|UniProtKB=Q5JUK3 Q5JUK3 KCNT1 PTHR10027:SF14 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;ion channel activity#GO:0005216;potassium ion transmembrane transporter activity#GO:0015079;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 ion channel#PC00133 HUMAN|HGNC=44409|UniProtKB=H3BPF8 H3BPF8 GOLGA8S PTHR10881:SF7 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8C-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=15746|UniProtKB=Q15785 Q15785 TOMM34 PTHR45984:SF2 RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM34 heat shock protein binding#GO:0031072;protein binding#GO:0005515;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28859|UniProtKB=Q9Y5L2 Q9Y5L2 HILPDA PTHR16886:SF0 HYPOXIA-INDUCIBLE PROTEIN 2 HYPOXIA-INDUCIBLE LIPID DROPLET-ASSOCIATED PROTEIN cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=14409|UniProtKB=Q9HC21 Q9HC21 SLC25A19 PTHR24089:SF59 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic cation transport#GO:0015695;anion transport#GO:0006820 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158 HUMAN|HGNC=2717|UniProtKB=Q16531 Q16531 DDB1 PTHR10644:SF3 DNA REPAIR/RNA PROCESSING CPSF FAMILY DNA DAMAGE-BINDING PROTEIN 1 damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular protein catabolic process#GO:0044257;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=18695|UniProtKB=O60284 O60284 ST18 PTHR10816:SF9 MYELIN TRANSCRIPTION FACTOR 1-RELATED SUPPRESSION OF TUMORIGENICITY 18 PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=11579|UniProtKB=O75347 O75347 TBCA PTHR21500:SF3 TUBULIN-SPECIFIC CHAPERONE A TUBULIN-SPECIFIC CHAPERONE A cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein folding#GO:0006457;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperonin#PC00073 HUMAN|HGNC=13935|UniProtKB=O95868 O95868 LY6G6D PTHR32286:SF9 LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6F LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6D cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;receptor regulator activity#GO:0030545;binding#GO:0005488;acetylcholine receptor activity#GO:0015464;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;acetylcholine receptor regulator activity#GO:0030548;acetylcholine binding#GO:0042166;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to nitrogen compound#GO:1901699;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=29937|UniProtKB=Q8IXS2 Q8IXS2 CCDC65 PTHR21625:SF0 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX SUBUNIT 2 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;regulation of cellular component movement#GO:0051270;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;axonemal dynein complex assembly#GO:0070286;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;regulation of microtubule-based process#GO:0032886;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=26495|UniProtKB=Q96DN0 Q96DN0 ERP27 PTHR18929:SF193 PROTEIN DISULFIDE ISOMERASE ENDOPLASMIC RETICULUM RESIDENT PROTEIN 27 isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;cellular process#GO:0009987;cellular response to stress#GO:0033554;protein folding#GO:0006457 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=19336|UniProtKB=Q149N8 Q149N8 SHPRH PTHR45865:SF1 E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE SHPRH ubiquitin-protein ligase#PC00234 HUMAN|HGNC=28164|UniProtKB=Q96M27 Q96M27 PRRC1 PTHR23276:SF2 UNCHARACTERIZED PROTEIN PRRC1 protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=38877|UniProtKB=P0CI26 P0CI26 TRIM49C PTHR24103:SF637 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 49-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=27334|UniProtKB=Q5JSJ4 Q5JSJ4 INTS6L PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED CANCER/TESTIS ANTIGEN FAMILY 45 MEMBER A1-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 RNA helicase#PC00032 HUMAN|HGNC=13485|UniProtKB=Q9BXU7 Q9BXU7 USP26 PTHR24006:SF711 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 26-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=453|UniProtKB=P02760 P02760 AMBP PTHR46676:SF1 PROTEIN AMBP PROTEIN AMBP serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=8575|UniProtKB=P68402 P68402 PAFAH1B2 PTHR11852:SF1 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA protein modifying enzyme#PC00260 HUMAN|HGNC=19300|UniProtKB=Q8N4C7 Q8N4C7 STX19 PTHR19957:SF29 SYNTAXIN SYNTAXIN-19 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;vesicle organization#GO:0016050;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;export from cell#GO:0140352 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 HUMAN|HGNC=133|UniProtKB=Q6S545 Q6S545 POTEH PTHR24118:SF94 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER E-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=13670|UniProtKB=Q15486 Q15486 GUSBP1 PTHR10066:SF67 BETA-GLUCURONIDASE BETA-GLUCURONIDASE-RELATED oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carbohydrate metabolic process#GO:0005975;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 HUMAN|HGNC=4517|UniProtKB=Q8IYL9 Q8IYL9 GPR65 PTHR24232:SF49 G-PROTEIN COUPLED RECEPTOR PSYCHOSINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=6731|UniProtKB=O76036 O76036 NCR1 PTHR11738:SF14 MHC CLASS I NK CELL RECEPTOR NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=3047|UniProtKB=P57055 P57055 RIPPLY3 PTHR16770:SF4 FAMILY NOT NAMED PROTEIN RIPPLY3 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=543|UniProtKB=P08758 P08758 ANXA5 PTHR10502:SF26 ANNEXIN ANNEXIN A5 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calcium-binding protein#PC00060 Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#G06684;Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#P06814;Gonadotropin-releasing hormone receptor pathway#P06664>Annexin A5#G06897 HUMAN|HGNC=17620|UniProtKB=Q9GZM8 Q9GZM8 NDEL1 PTHR10921:SF0 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 vesicle transport along microtubule#GO:0047496;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;nuclear division#GO:0000280;microtubule-based movement#GO:0007018;centrosome cycle#GO:0007098;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of multicellular organismal process#GO:0051239;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;microtubule organizing center organization#GO:0031023;transport along microtubule#GO:0010970;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;establishment of mitotic spindle orientation#GO:0000132;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;centrosome localization#GO:0051642;neuron development#GO:0048666;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;chromosome localization#GO:0050000;locomotion#GO:0040011;establishment or maintenance of cell polarity#GO:0007163;neurogenesis#GO:0022008;developmental process#GO:0032502;establishment of spindle orientation#GO:0051294;transport#GO:0006810;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;mitotic cell cycle process#GO:1903047;system development#GO:0048731;cell differentiation#GO:0030154;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;mitotic nuclear division#GO:0140014;spindle localization#GO:0051653;regulation of cell development#GO:0060284;establishment of chromosome localization#GO:0051303;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;cell motility#GO:0048870;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;localization#GO:0051179;cell development#GO:0048468;establishment of mitotic spindle localization#GO:0040001;microtubule-based transport#GO:0099111;regulation of neurogenesis#GO:0050767;microtubule-based process#GO:0007017;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;biological regulation#GO:0065007;protein polymerization#GO:0051258;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;generation of neurons#GO:0048699;cell migration#GO:0016477;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;kinetochore#GO:0000776;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;chromosomal region#GO:0098687;cytoskeleton#GO:0005856 HUMAN|HGNC=13920|UniProtKB=O95872 O95872 GPANK1 PTHR20923:SF1 BAT4 PROTEIN-RELATED G PATCH DOMAIN AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 HUMAN|HGNC=34187|UniProtKB=Q9H1X3 Q9H1X3 DNAJC25 PTHR44176:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 DNAJ HOMOLOG SUBFAMILY C MEMBER 25 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=4916|UniProtKB=P54198 P54198 HIRA PTHR13831:SF0 MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS PROTEIN HIRA nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;transcription corepressor activity#GO:0003714;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;nucleosome assembly#GO:0006334;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of chromatin silencing#GO:0031935;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of chromatin organization#GO:1902275;regulation of gene expression, epigenetic#GO:0040029;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;DNA replication-independent nucleosome organization#GO:0034724;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;nucleosome organization#GO:0034728;negative regulation of biological process#GO:0048519;chromatin assembly or disassembly#GO:0006333;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;mitotic cell cycle process#GO:1903047;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=2991|UniProtKB=O60496 O60496 DOK2 PTHR21258:SF14 DOCKING PROTEIN RELATED DOCKING PROTEIN 2 Angiogenesis#P00005>Dok-R#P00180 HUMAN|HGNC=7817|UniProtKB=Q02575 Q02575 NHLH1 PTHR13864:SF20 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED HELIX-LOOP-HELIX PROTEIN 1 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=30467|UniProtKB=Q6ZT12 Q6ZT12 UBR3 PTHR21497:SF39 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR3 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=10861|UniProtKB=Q96JF0 Q96JF0 ST6GAL2 PTHR46059:SF3 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 2 transferase#PC00220 HUMAN|HGNC=18746|UniProtKB=P55000 P55000 SLURP1 PTHR10036:SF17 CD59 GLYCOPROTEIN SECRETED LY-6/UPAR-RELATED PROTEIN 1 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;receptor regulator activity#GO:0030545;acetylcholine receptor activity#GO:0015464;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;molecular transducer activity#GO:0060089;acetylcholine receptor regulator activity#GO:0030548;neurotransmitter receptor activity#GO:0030594;acetylcholine binding#GO:0042166;ion binding#GO:0043167;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 HUMAN|HGNC=8091|UniProtKB=P04181 P04181 OAT PTHR11986:SF118 AMINOTRANSFERASE CLASS III ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;identical protein binding#GO:0042802;transaminase activity#GO:0008483;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;arginine catabolic process#GO:0006527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;organic cyclic compound metabolic process#GO:1901360;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transaminase#PC00216 HUMAN|HGNC=18889|UniProtKB=Q6J9G0 Q6J9G0 STYK1 PTHR24418:SF269 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE STYK1 protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;cell population proliferation#GO:0008283;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;innate immune response#GO:0045087;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;peptidyl-tyrosine modification#GO:0018212;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 HUMAN|HGNC=13655|UniProtKB=Q8IX30 Q8IX30 SCUBE3 PTHR24046:SF2 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=16660|UniProtKB=Q96RJ6 Q96RJ6 FERD3L PTHR23349:SF63 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FER3-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=8491|UniProtKB=O43913 O43913 ORC5 PTHR12705:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;DNA biosynthetic process#GO:0071897;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 replication origin binding protein#PC00199 HUMAN|HGNC=19861|UniProtKB=Q6ZMZ3 Q6ZMZ3 SYNE3 PTHR47535:SF2 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G NESPRIN-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 localization#GO:0051179;nuclear migration#GO:0007097;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of organelle localization#GO:0051656;nucleus localization#GO:0051647 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;organelle outer membrane#GO:0031968;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;plasma membrane#GO:0005886 HUMAN|HGNC=20330|UniProtKB=Q9Y244 Q9Y244 POMP PTHR12828:SF3 PROTEASOME MATURATION PROTEIN UMP1 PROTEASOME MATURATION PROTEIN proteasome assembly#GO:0043248;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=30873|UniProtKB=Q96H22 Q96H22 CENPN PTHR46790:SF1 CENTROMERE PROTEIN N CENTROMERE PROTEIN N HUMAN|HGNC=9059|UniProtKB=Q15147 Q15147 PLCB4 PTHR10336:SF106 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 phospholipase#PC00186 Metabotropic glutamate receptor group I pathway#P00041>PLC#P01053;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PLC#P01068;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Phospholipase C-beta#P00744;Endothelin signaling pathway#P00019>PLCbeta#P00591;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484 HUMAN|HGNC=42787|UniProtKB=P0DPH9 P0DPH9 CXorf51B PTHR37876:SF1 PROTEIN GAR2-LIKE PROTEIN GAR2-LIKE HUMAN|HGNC=44651|UniProtKB=H3BTG2 H3BTG2 TEX46 PTHR39412:SF1 TESTIS-EXPRESSED PROTEIN 46 TESTIS-EXPRESSED PROTEIN 46 HUMAN|HGNC=10931|UniProtKB=O00476 O00476 SLC17A3 PTHR11662:SF134 SOLUTE CARRIER FAMILY 17 SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;xenobiotic transmembrane transporter activity#GO:0042910;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;efflux transmembrane transporter activity#GO:0015562;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;inorganic anion transmembrane transporter activity#GO:0015103 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=1573|UniProtKB=O00522 O00522 KRIT1 PTHR13283:SF11 KREV INTERACTION TRAPPED 1-RELATED KREV INTERACTION TRAPPED PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=13867|UniProtKB=Q96B97 Q96B97 SH3KBP1 PTHR14167:SF6 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING KINASE-BINDING PROTEIN 1 HUMAN|Ensembl=ENSG00000284217|UniProtKB=A0A376A8Z9 A0A376A8Z9 KIR2DS5 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=34026|UniProtKB=Q5VTU8 Q5VTU8 ATP5F1EP2 PTHR12448:SF2 ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL ATP SYNTHASE SUBUNIT EPSILON-LIKE PROTEIN, MITOCHONDRIAL pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002 HUMAN|HGNC=29681|UniProtKB=Q9BSK2 Q9BSK2 SLC25A33 PTHR45829:SF5 MITOCHONDRIAL CARRIER PROTEIN RIM2 SOLUTE CARRIER FAMILY 25 MEMBER 33 organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;nucleotide transmembrane transporter activity#GO:0015215;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleotide transport#GO:0006862;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;nitrogen compound transport#GO:0071705;nucleotide transmembrane transport#GO:1901679;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542 mitochondrial carrier protein#PC00158 HUMAN|HGNC=19365|UniProtKB=Q9H999 Q9H999 PANK3 PTHR12280:SF21 PANTOTHENATE KINASE PANTOTHENATE KINASE 3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 HUMAN|HGNC=18607|UniProtKB=Q13433 Q13433 SLC39A6 PTHR12191:SF22 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP6 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=8117|UniProtKB=Q9UKZ4 Q9UKZ4 TENM1 PTHR11219:SF7 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-1 identical protein binding#GO:0042802;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein homodimerization activity#GO:0042803;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=14737|UniProtKB=Q8NH79 Q8NH79 OR6X1 PTHR26454:SF30 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=10738|UniProtKB=Q9H2E6 Q9H2E6 SEMA6A PTHR11036:SF12 SEMAPHORIN SEMAPHORIN-6A receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;negative regulation of cellular component organization#GO:0051129;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;negative regulation of locomotion#GO:0040013;neuron projection extension#GO:1990138;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;locomotion#GO:0040011;positive regulation of multicellular organismal process#GO:0051240;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;signal transduction#GO:0007165;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;growth#GO:0040007;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;developmental growth involved in morphogenesis#GO:0060560;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of cell differentiation#GO:0045597;regulation of cell motility#GO:2000145;regulation of cell development#GO:0060284;developmental growth#GO:0048589;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell motility#GO:0048870;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;positive regulation of developmental process#GO:0051094;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of cell migration#GO:0030335;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;neuron migration#GO:0001764;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=6597|UniProtKB=P42702 P42702 LIFR PTHR23036:SF105 CYTOKINE RECEPTOR LEUKEMIA INHIBITORY FACTOR RECEPTOR signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;cytokine receptor binding#GO:0005126 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;cellular response to organic substance#GO:0071310;positive regulation of cell population proliferation#GO:0008284;cell communication#GO:0007154;cell population proliferation#GO:0008283;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;positive regulation of biological process#GO:0048518;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=23568|UniProtKB=Q75LS8 Q75LS8 FKBP9P1 PTHR46046:SF2 FAMILY NOT NAMED FK506-BINDING PROTEIN 9-LIKE PROTEIN-RELATED HUMAN|HGNC=2001|UniProtKB=O60565 O60565 GREM1 PTHR15283:SF3 GREMLIN 1 GREMLIN-1 receptor regulator activity#GO:0030545;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;animal organ development#GO:0048513;negative regulation of cellular response to growth factor stimulus#GO:0090288;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;system development#GO:0048731;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=31986|UniProtKB=Q3SYB3 Q3SYB3 FOXD4L6 PTHR11829:SF381 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-LIKE 3-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=12789|UniProtKB=Q93098 Q93098 WNT8B PTHR12027:SF94 WNT RELATED PROTEIN WNT-8B receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=28489|UniProtKB=Q8NEP7 Q8NEP7 KLHDC9 PTHR47196:SF1 KELCH DOMAIN-CONTAINING PROTEIN 9 KELCH DOMAIN-CONTAINING PROTEIN 9 protein binding#GO:0005515;cyclin binding#GO:0030332;binding#GO:0005488 HUMAN|HGNC=15521|UniProtKB=Q9NZI2 Q9NZI2 KCNIP1 PTHR23055:SF82 CALCIUM BINDING PROTEINS KV CHANNEL-INTERACTING PROTEIN 1 HUMAN|HGNC=15518|UniProtKB=Q9UJW0 Q9UJW0 DCTN4 PTHR13034:SF2 DYNACTIN P62 SUBUNIT DYNACTIN SUBUNIT 4 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156 HUMAN|HGNC=18111|UniProtKB=Q8IVM0 Q8IVM0 CCDC50 PTHR22115:SF1 C3ORF6 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 50 HUMAN|HGNC=409|UniProtKB=P47895 P47895 ALDH1A3 PTHR11699:SF209 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=9119|UniProtKB=O75439 O75439 PMPCB PTHR11851:SF103 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT BETA hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;mitochondrial protein processing#GO:0034982;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;establishment of protein localization#GO:0045184;protein processing#GO:0016485;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein processing involved in protein targeting to mitochondrion#GO:0006627;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 metalloprotease#PC00153 HUMAN|HGNC=26920|UniProtKB=Q96G46 Q96G46 DUS3L PTHR45846:SF1 TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a tRNA#GO:0140101;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 RNA processing factor#PC00147 HUMAN|HGNC=2644|UniProtKB=P13584 P13584 CYP4B1 PTHR24291:SF149 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4B1 oxygenase#PC00177 HUMAN|HGNC=24693|UniProtKB=O94851 O94851 MICAL2 PTHR23167:SF39 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL2 HUMAN|HGNC=26889|UniProtKB=Q3SXZ3 Q3SXZ3 ZNF718 PTHR24384:SF208 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 718 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=10058|UniProtKB=Q9UBS8 Q9UBS8 RNF14 PTHR11685:SF290 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF14 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=29811|UniProtKB=Q496H8 Q496H8 NRN1L PTHR15902:SF2 NEURITIN-RELATED NEURITIN-LIKE PROTEIN HUMAN|HGNC=37285|UniProtKB=Q8N7X2 Q8N7X2 STPG3 PTHR21580:SF25 SHIPPO-1-RELATED PROTEIN STPG3 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 structural protein#PC00211 HUMAN|HGNC=17857|UniProtKB=Q86WT6 Q86WT6 TRIM69 PTHR24103:SF286 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM69 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=6221|UniProtKB=P22001 P22001 KCNA3 PTHR11537:SF28 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=9122|UniProtKB=P54278 P54278 PMS2 PTHR10073:SF52 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MISMATCH REPAIR ENDONUCLEASE PMS2-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=4432|UniProtKB=P17174 P17174 GOT1 PTHR11879:SF3 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, CYTOPLASMIC transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transaminase#PC00216 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 HUMAN|HGNC=19665|UniProtKB=Q5T5C0 Q5T5C0 STXBP5 PTHR10241:SF22 LETHAL 2 GIANT LARVAE PROTEIN SYNTAXIN-BINDING PROTEIN 5 GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;myosin binding#GO:0017022;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;syntaxin binding#GO:0019905;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;protein secretion#GO:0009306;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;amide transport#GO:0042886;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;regulation of protein transport#GO:0051223;regulation of protein localization#GO:0032880;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;regulation of protein secretion#GO:0050708;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;intracellular#GO:0005622;SNARE complex#GO:0031201;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=29410|UniProtKB=Q2NKQ1 Q2NKQ1 SGSM1 PTHR22957:SF187 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 1 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=4839|UniProtKB=P51610 P51610 HCFC1 PTHR46003:SF3 HOST CELL FACTOR HOST CELL FACTOR 1 transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of nucleic acid-templated transcription#GO:1903506;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=9412|UniProtKB=Q05513 Q05513 PRKCZ PTHR24356:SF170 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C ZETA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKCzeta#P00829;EGF receptor signaling pathway#P00018>PKC#P00565;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKC#P00861;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 HUMAN|HGNC=27934|UniProtKB=Q6IQ16 Q6IQ16 SPOPL PTHR24413:SF91 SPECKLE-TYPE POZ PROTEIN SPECKLE-TYPE POZ PROTEIN-LIKE enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=22398|UniProtKB=Q96EE4 Q96EE4 CCDC126 PTHR46941:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 126 COILED-COIL DOMAIN-CONTAINING PROTEIN 126 HUMAN|HGNC=26057|UniProtKB=Q9NWW6 Q9NWW6 NMRK1 PTHR10285:SF126 URIDINE KINASE NICOTINAMIDE RIBOSIDE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 nucleotide kinase#PC00172 HUMAN|HGNC=18568|UniProtKB=Q96LI6 Q96LI6 HSFY2 PTHR10015:SF336 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK TRANSCRIPTION FACTOR, Y-LINKED winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=33193|UniProtKB=Q6MZM9 Q6MZM9 PRR27 PTHR39415:SF1 PROLINE-RICH PROTEIN 27 PROLINE-RICH PROTEIN 27 membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 HUMAN|HGNC=2738|UniProtKB=O43143 O43143 DHX15 PTHR18934:SF95 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX15 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA helicase#PC00032 HUMAN|HGNC=20775|UniProtKB=Q9UJT0 Q9UJT0 TUBE1 PTHR11588:SF317 TUBULIN TUBULIN EPSILON CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 HUMAN|HGNC=29314|UniProtKB=Q5VU97 Q5VU97 CACHD1 PTHR10166:SF40 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VWFA AND CACHE DOMAIN-CONTAINING PROTEIN 1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;channel activity#GO:0015267;transporter activity#GO:0005215;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=19255|UniProtKB=Q5JTB6 Q5JTB6 PLAC9 PTHR37355:SF1 PLACENTA-SPECIFIC PROTEIN 9 PLACENTA-SPECIFIC PROTEIN 9 HUMAN|HGNC=21475|UniProtKB=Q6ZRQ5 Q6ZRQ5 MMS22L PTHR28547:SF1 PROTEIN MMS22-LIKE PROTEIN MMS22-LIKE HUMAN|HGNC=9590|UniProtKB=Q96BW5 Q96BW5 PTER PTHR10819:SF3 PHOSPHOTRIESTERASE-RELATED PHOSPHOTRIESTERASE-RELATED PROTEIN esterase#PC00097 HUMAN|HGNC=636|UniProtKB=Q92482 Q92482 AQP3 PTHR43829:SF7 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-3 amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 HUMAN|HGNC=7571|UniProtKB=Q9UKX3 Q9UKX3 MYH13 PTHR45615:SF44 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-13 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=26440|UniProtKB=Q6GMR7 Q6GMR7 FAAH2 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 hydrolase#PC00121 HUMAN|HGNC=25323|UniProtKB=A4QPB2 A4QPB2 LRP5L PTHR46513:SF16 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 5-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>LRP5/6#P01431;Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 HUMAN|HGNC=32460|UniProtKB=A8MTY0 A8MTY0 ZNF724 PTHR24384:SF201 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 273-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=8795|UniProtKB=O76083 O76083 PDE9A PTHR11347:SF141 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 9A hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-GMP phosphodiesterase activity#GO:0047555;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;heterocycle catabolic process#GO:0046700;cyclic nucleotide metabolic process#GO:0009187;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;intracellular signal transduction#GO:0035556;organic substance catabolic process#GO:1901575;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organophosphate catabolic process#GO:0046434;response to stimulus#GO:0050896;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;cyclic-nucleotide-mediated signaling#GO:0019935;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 phosphodiesterase#PC00185 HUMAN|HGNC=1135|UniProtKB=Q13410 Q13410 BTN1A1 PTHR24100:SF116 BUTYROPHILIN BUTYROPHILIN SUBFAMILY 1 MEMBER A1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;gene expression#GO:0010467;cytokine production#GO:0001816;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;regulation of cytokine production#GO:0001817;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of metabolic process#GO:0019222;T cell receptor signaling pathway#GO:0050852 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=22219|UniProtKB=Q9HCM3 Q9HCM3 KIAA1549 PTHR21590:SF4 UNCHARACTERIZED UPF0606 PROTEIN KIAA1549 HUMAN|HGNC=6315|UniProtKB=P50053 P50053 KHK PTHR43085:SF1 HEXOKINASE FAMILY MEMBER KETOHEXOKINASE carbohydrate kinase#PC00065 Fructose galactose metabolism#P02744>Ketohexokinase#P02963 HUMAN|HGNC=11126|UniProtKB=P53814 P53814 SMTN PTHR23167:SF52 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED SMOOTHELIN cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856 HUMAN|HGNC=23488|UniProtKB=B1APH4 B1APH4 ZNF487 PTHR24381:SF346 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 177-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6588|UniProtKB=Q6ZUX7 Q6ZUX7 LHFPL2 PTHR12489:SF19 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 2 PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=758|UniProtKB=P00966 P00966 ASS1 PTHR11587:SF5 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE ligase activity#GO:0016874;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 Arginine biosynthesis#P02728>Argininosuccinate synthase#P02840 HUMAN|HGNC=2153|UniProtKB=Q9NQW8 Q9NQW8 CNGB3 PTHR45638:SF8 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL BETA-3 cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;inorganic molecular entity transmembrane transporter activity#GO:0015318;nucleotide binding#GO:0000166;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;purine nucleotide binding#GO:0017076;gated channel activity#GO:0022836;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 ligand-gated ion channel#PC00141 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>cGMP-gated ion channel#P00752 HUMAN|HGNC=20662|UniProtKB=Q6NUK1 Q6NUK1 SLC25A24 PTHR24089:SF262 SOLUTE CARRIER FAMILY 25 CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN SCAMC-1 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ATP transmembrane transporter activity#GO:0005347;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;ion transmembrane transporter activity#GO:0015075;nucleotide transmembrane transporter activity#GO:0015215;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 mitochondrial carrier protein#PC00158 HUMAN|HGNC=1971|UniProtKB=Q7LGC8 Q7LGC8 CHST3 PTHR10704:SF60 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 3 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;chondroitin sulfate metabolic process#GO:0030204;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;proteoglycan metabolic process#GO:0006029;chondroitin sulfate proteoglycan metabolic process#GO:0050654;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;glycosaminoglycan biosynthetic process#GO:0006024;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281 transferase#PC00220 HUMAN|HGNC=25982|UniProtKB=Q5T3I0 Q5T3I0 GPATCH4 PTHR23149:SF9 G PATCH DOMAIN CONTAINING PROTEIN G PATCH DOMAIN-CONTAINING PROTEIN 4 RNA metabolism protein#PC00031 HUMAN|HGNC=2915|UniProtKB=Q07687 Q07687 DLX2 PTHR24327:SF23 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=24110|UniProtKB=O14530 O14530 TXNDC9 PTHR21148:SF11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 protein-binding activity modulator#PC00095 HUMAN|HGNC=6528|UniProtKB=P13796 P13796 LCP1 PTHR19961:SF35 FIMBRIN/PLASTIN PLASTIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin filament bundle organization#GO:0061572;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=9015|UniProtKB=Q9NTG1 Q9NTG1 PKDREJ PTHR10877:SF185 POLYCYSTIN FAMILY MEMBER POLYCYSTIC KIDNEY DISEASE AND RECEPTOR FOR EGG JELLY-RELATED PROTEIN calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133 HUMAN|HGNC=29423|UniProtKB=Q8N782 Q8N782 ZNF525 PTHR23226:SF324 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 525-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=19347|UniProtKB=O14529 O14529 CUX2 PTHR14043:SF5 CCAAT DISPLACEMENT PROTEIN-RELATED HOMEOBOX PROTEIN CUT-LIKE 2 homeodomain transcription factor#PC00119 HUMAN|HGNC=20295|UniProtKB=O94991 O94991 SLITRK5 PTHR45773:SF5 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 5 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;generation of neurons#GO:0048699;cell part morphogenesis#GO:0032990 HUMAN|HGNC=18337|UniProtKB=Q9ULW8 Q9ULW8 PADI3 PTHR10837:SF21 PEPTIDYLARGININE DEIMINASE PROTEIN-ARGININE DEIMINASE TYPE-3 HUMAN|HGNC=30771|UniProtKB=Q8IYF1 Q8IYF1 ELOA2 PTHR15141:SF7 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN-A2 HUMAN|HGNC=31930|UniProtKB=Q6ZS27 Q6ZS27 ZNF662 PTHR24390:SF39 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 662 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11377|UniProtKB=P49888 P49888 SULT1E1 PTHR11783:SF53 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1E1 transferase#PC00220 HUMAN|HGNC=28418|UniProtKB=Q5T5D7 Q5T5D7 ZNF684 PTHR24381:SF0 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 684 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26358|UniProtKB=Q8IYE1 Q8IYE1 CCDC13 PTHR31935:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 COILED-COIL DOMAIN-CONTAINING PROTEIN 13 HUMAN|HGNC=30288|UniProtKB=Q9NZJ0 Q9NZJ0 DTL PTHR22852:SF0 LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN DENTICLELESS PROTEIN HOMOLOG HUMAN|HGNC=24933|UniProtKB=Q6UXH0 Q6UXH0 ANGPTL8 PTHR21463:SF0 ANGIOPOIETIN-LIKE PROTEIN 8 ANGIOPOIETIN-LIKE PROTEIN 8 HUMAN|HGNC=7897|UniProtKB=O15118 O15118 NPC1 PTHR45727:SF2 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 HUMAN|HGNC=30533|UniProtKB=A0A1B0GTR3 A0A1B0GTR3 CXorf51A PTHR37876:SF1 PROTEIN GAR2-LIKE PROTEIN GAR2-LIKE HUMAN|HGNC=17136|UniProtKB=Q8IY81 Q8IY81 FTSJ3 PTHR10920:SF13 RIBOSOMAL RNA METHYLTRANSFERASE PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3 catalytic activity, acting on RNA#GO:0140098;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;methylation#GO:0032259;macromolecule methylation#GO:0043414;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 RNA methyltransferase#PC00033 HUMAN|HGNC=12519|UniProtKB=P55916 P55916 UCP3 PTHR45618:SF2 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to stress#GO:0006950;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;response to cold#GO:0009409;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152 secondary carrier transporter#PC00258 HUMAN|HGNC=19109|UniProtKB=P59543 P59543 TAS2R20 PTHR11394:SF27 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 20 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=16526|UniProtKB=Q9ULC5 Q9ULC5 ACSL5 PTHR43272:SF85 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 5 ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 ligase#PC00142 HUMAN|HGNC=21732|UniProtKB=P58335 P58335 ANTXR2 PTHR16059:SF13 ANTHRAX TOXIN RECEPTOR ANTHRAX TOXIN RECEPTOR 2 cell adhesion molecule#PC00069 HUMAN|HGNC=8196|UniProtKB=Q96R84 Q96R84 OR1F2P PTHR48001:SF98 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1F1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=11814|UniProtKB=P62072 P62072 TIMM10 PTHR11038:SF16 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 cellular localization#GO:0051641;protein insertion into mitochondrial inner membrane#GO:0045039;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 transporter#PC00227 HUMAN|HGNC=8512|UniProtKB=P00480 P00480 OTC PTHR45753:SF3 ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 Arginine biosynthesis#P02728>Ornithine carbamoyl transferase#P02846 HUMAN|HGNC=4183|UniProtKB=P32456 P32456 GBP2 PTHR10751:SF112 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN 2 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830 heterotrimeric G-protein#PC00117 HUMAN|HGNC=339|UniProtKB=P35414 P35414 APLNR PTHR24228:SF31 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR APELIN RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 heart development#GO:0007507;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;second-messenger-mediated signaling#GO:0019932;negative regulation of intracellular signal transduction#GO:1902532;animal organ development#GO:0048513;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of signal transduction#GO:0009966;vasculature development#GO:0001944;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 G-protein coupled receptor#PC00021 HUMAN|HGNC=3098|UniProtKB=O14656 O14656 TOR1A PTHR10760:SF15 TORSIN TORSIN-1A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;protein localization to nucleus#GO:0034504;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;nuclear envelope organization#GO:0006998 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 HUMAN|HGNC=11656|UniProtKB=Q12799 Q12799 TCP10L3 PTHR10331:SF25 T COMPLEX PROTEIN 10 T-COMPLEX PROTEIN 10A HOMOLOG 1-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;nitrogen compound transport#GO:0071705;centrosome duplication#GO:0051298;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;peptide transport#GO:0015833;microtubule organizing center organization#GO:0031023;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;centriole replication#GO:0007099;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=14268|UniProtKB=Q9HCL0 Q9HCL0 PCDH18 PTHR24028:SF9 CADHERIN-87A PROTOCADHERIN-18 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=3227|UniProtKB=P52799 P52799 EFNB2 PTHR11304:SF18 EPHRIN EPHRIN-B2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;tube morphogenesis#GO:0035239;neuron differentiation#GO:0030182;vasculature development#GO:0001944;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;cell morphogenesis involved in differentiation#GO:0000904;blood vessel morphogenesis#GO:0048514;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;tube development#GO:0035295;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 Angiogenesis#P00005>Eph#P00239 HUMAN|HGNC=19031|UniProtKB=Q8IZP1 Q8IZP1 TBC1D3 PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=18410|UniProtKB=O60281 O60281 ZNF292 PTHR15507:SF14 ZINC FINGER PROTEIN RLF ZINC FINGER PROTEIN 292 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=24615|UniProtKB=O00418 O00418 EEF2K PTHR45992:SF2 EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED EUKARYOTIC ELONGATION FACTOR 2 KINASE Oxidative stress response#P00046>eEF2K#P01127;p38 MAPK pathway#P05918>eEF2K#P06022 HUMAN|HGNC=5994|UniProtKB=P27930 P27930 IL1R2 PTHR11890:SF3 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR TYPE 2 transmembrane signal receptor#PC00197 HUMAN|HGNC=9024|UniProtKB=Q99959 Q99959 PKP2 PTHR10372:SF25 PLAKOPHILLIN-RELATED PLAKOPHILIN-2 molecular adaptor activity#GO:0060090;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein-containing complex binding#GO:0044877;kinase binding#GO:0019900 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;heart development#GO:0007507;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;animal organ development#GO:0048513;developmental process#GO:0032502;biological adhesion#GO:0022610;system development#GO:0048731;supramolecular fiber organization#GO:0097435;cytoskeleton organization#GO:0007010;cell junction assembly#GO:0034329;intermediate filament cytoskeleton organization#GO:0045104;protein localization to plasma membrane#GO:0072659;cell-cell junction organization#GO:0045216;cellular component assembly#GO:0022607;circulatory system development#GO:0072359;cell-cell junction assembly#GO:0007043;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;multicellular organismal process#GO:0032501 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;intermediate filament#GO:0005882;anchoring junction#GO:0070161;cell junction#GO:0030054;intermediate filament cytoskeleton#GO:0045111;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;cell-cell contact zone#GO:0044291;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130 HUMAN|HGNC=10640|UniProtKB=O95715 O95715 CXCL14 PTHR15188:SF0 C-X-C MOTIF CHEMOKINE 14 C-X-C MOTIF CHEMOKINE 14 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844 chemokine#PC00074 HUMAN|HGNC=26735|UniProtKB=Q2TAC6 Q2TAC6 KIF19 PTHR24115:SF434 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF19 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;ATP-dependent microtubule motor activity, plus-end-directed#GO:0008574;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=8180|UniProtKB=Q9Y585 Q9Y585 OR1A2 PTHR48001:SF50 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1A1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=17950|UniProtKB=Q969J3 Q969J3 BORCS5 PTHR31634:SF2 BLOC-1-RELATED COMPLEX SUBUNIT 5 BLOC-1-RELATED COMPLEX SUBUNIT 5 vesicle transport along microtubule#GO:0047496;regulation of microtubule-based process#GO:0032886;cellular localization#GO:0051641;organelle localization#GO:0051640;transport#GO:0006810;microtubule-based movement#GO:0007018;regulation of localization#GO:0032879;positive regulation of cellular component movement#GO:0051272;lysosome localization#GO:0032418;regulation of biological process#GO:0050789;axo-dendritic transport#GO:0008088;regulation of transport#GO:0051049;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;synaptic vesicle transport#GO:0048489;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of cellular component movement#GO:0051270;vesicle localization#GO:0051648;positive regulation of transport#GO:0051050;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;transport along microtubule#GO:0010970;positive regulation of cellular process#GO:0048522;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;non-membrane-bounded organelle#GO:0043228;intrinsic component of membrane#GO:0031224;lysosome#GO:0005764;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoplasmic vesicle membrane#GO:0030659;cytoplasmic side of membrane#GO:0098562;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;leaflet of membrane bilayer#GO:0097478;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;lytic vacuole#GO:0000323;side of membrane#GO:0098552;whole membrane#GO:0098805;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=30281|UniProtKB=Q9NZL6 Q9NZL6 RGL1 PTHR23113:SF199 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE 1 guanyl-nucleotide exchange factor#PC00113 Ras Pathway#P04393>RalGDS#P04551 HUMAN|HGNC=17978|UniProtKB=Q96L58 Q96L58 B3GALT6 PTHR11214:SF3 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 6 glycosyltransferase#PC00111 HUMAN|HGNC=21185|UniProtKB=Q8NA58 Q8NA58 PNLDC1 PTHR15092:SF22 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 POLY(A)-SPECIFIC RIBONUCLEASE PNLDC1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=14335|UniProtKB=Q9HB21 Q9HB21 PLEKHA1 PTHR14336:SF4 TANDEM PH DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 1 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=13780|UniProtKB=Q96RP9 Q96RP9 GFM1 PTHR43636:SF2 ELONGATION FACTOR G, MITOCHONDRIAL ELONGATION FACTOR G, MITOCHONDRIAL GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;translation regulator activity#GO:0045182;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111 HUMAN|HGNC=11609|UniProtKB=P24557 P24557 TBXAS1 PTHR24301:SF2 THROMBOXANE-A SYNTHASE THROMBOXANE-A SYNTHASE isomerase#PC00135 HUMAN|Ensembl=ENSG00000266826|UniProtKB=A0A1W2PR95 A0A1W2PR95 ENSG00000266826 PTHR10933:SF15 IMMUNOGLOBULIN-BINDING PROTEIN 1 HCG1642624, ISOFORM CRA_A phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of phosphate metabolic process#GO:0019220;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of dephosphorylation#GO:0035303;cellular metabolic process#GO:0044237;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;phosphorus metabolic process#GO:0006793;regulation of cellular metabolic process#GO:0031323;phosphate-containing compound metabolic process#GO:0006796;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=7411|UniProtKB=O94776 O94776 MTA2 PTHR10865:SF4 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA2 repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription coactivator activity#GO:0003713;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 p53 pathway#P00059>MTA2#P04615 HUMAN|HGNC=14615|UniProtKB=Q9BXP8 Q9BXP8 PAPPA2 PTHR46130:SF1 LAMGL DOMAIN-CONTAINING PROTEIN PAPPALYSIN-2 HUMAN|HGNC=5464|UniProtKB=P05019 P05019 IGF1 PTHR46845:SF1 INSULIN-LIKE GROWTH FACTOR I INSULIN-LIKE GROWTH FACTOR I growth factor#PC00112 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Insulin IGF#P00896;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Gonadotropin-releasing hormone receptor pathway#P06664>IGF-1#P06854 HUMAN|HGNC=3680|UniProtKB=Q9GZV9 Q9GZV9 FGF23 PTHR11486:SF69 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 23 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=6915|UniProtKB=P02144 P02144 MB PTHR47132:SF1 MYOGLOBIN MYOGLOBIN small molecule binding#GO:0036094;binding#GO:0005488 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 HUMAN|HGNC=27563|UniProtKB=A6NFC5 A6NFC5 TMEM235 PTHR20516:SF1 TRANSMEMBRANE PROTEIN 114/235 FAMILY MEMBER TRANSMEMBRANE PROTEIN 235 plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 HUMAN|HGNC=26014|UniProtKB=Q9NX74 Q9NX74 DUS2 PTHR45936:SF1 TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA processing factor#PC00147 HUMAN|HGNC=2501|UniProtKB=P32929 P32929 CTH PTHR11808:SF15 TRANS-SULFURATION ENZYME FAMILY MEMBER CYSTATHIONINE GAMMA-LYASE small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 lyase#PC00144 Methionine biosynthesis#P02753>O-Succinyl homoserine lyase#P03026 HUMAN|HGNC=6181|UniProtKB=Q14571 Q14571 ITPR2 PTHR13715:SF53 RYANODINE RECEPTOR AND IP3 RECEPTOR INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 2 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;metal ion binding#GO:0046872;ion transmembrane transporter activity#GO:0015075;phospholipid binding#GO:0005543;transporter activity#GO:0005215;channel activity#GO:0015267;cation binding#GO:0043169;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;sequestering of calcium ion#GO:0051208;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;negative regulation of cellular process#GO:0048523;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;release of sequestered calcium ion into cytosol#GO:0051209;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;regulation of cellular localization#GO:0060341;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065;negative regulation of sequestering of calcium ion#GO:0051283 bounding membrane of organelle#GO:0098588;sarcoplasmic reticulum#GO:0016529;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;secretory granule#GO:0030141;sarcoplasm#GO:0016528;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783;secretory vesicle#GO:0099503;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Histamine H1 receptor mediated signaling pathway#P04385>IP3R#P04486;Endothelin signaling pathway#P00019>IP3 R#P00590;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>IP3R#P01064;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IP3R#P00842;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>IP3 channel#P00735;Gonadotropin-releasing hormone receptor pathway#P06664>IP3R#P06768;B cell activation#P00010>IP3R#P00398;Wnt signaling pathway#P00057>IP3 Gated Calcium Channel#P01426;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>IP3R#P05932;PDGF signaling pathway#P00047>IP3 receptor#P01160 HUMAN|HGNC=11216|UniProtKB=O75391 O75391 SPAG7 PTHR13498:SF3 SPERM ASSOCIATED ANTIGEN 7 SPERM-ASSOCIATED ANTIGEN 7 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=26882|UniProtKB=Q8N7M0 Q8N7M0 TCTEX1D1 PTHR21255:SF44 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN TCTEX1 DOMAIN-CONTAINING PROTEIN 1 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=25092|UniProtKB=Q7L2R6 Q7L2R6 ZNF765 PTHR24377:SF765 IP01015P-RELATED ZINC FINGER PROTEIN 765 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19034|UniProtKB=Q9Y2H9 Q9Y2H9 MAST1 PTHR24356:SF150 SERINE/THREONINE-PROTEIN KINASE MICROTUBULE-ASSOCIATED SERINE/THREONINE-PROTEIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=30142|UniProtKB=Q99988 Q99988 GDF15 PTHR11848:SF78 TGF-BETA FAMILY GROWTH/DIFFERENTIATION FACTOR 15 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=29152|UniProtKB=Q7L804 Q7L804 RAB11FIP2 PTHR15746:SF20 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 2 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;regulated exocytosis#GO:0045055;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=6261|UniProtKB=Q99712 Q99712 KCNJ15 PTHR11767:SF20 INWARD RECTIFIER POTASSIUM CHANNEL ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 15 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=8881|UniProtKB=P07737 P07737 PFN1 PTHR13936:SF14 PROFILIN PROFILIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 HUMAN|HGNC=7895|UniProtKB=Q99743 Q99743 NPAS2 PTHR46055:SF1 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT NEURONAL PAS DOMAIN-CONTAINING PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;multicellular organismal process#GO:0032501;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=13073|UniProtKB=P17035 P17035 ZNF28 PTHR24377:SF301 IP01015P-RELATED ZINC FINGER PROTEIN 28 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2409|UniProtKB=P07316 P07316 CRYGB PTHR11818:SF101 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN B structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=13913|UniProtKB=Q96MA1 Q96MA1 DMRTB1 PTHR12322:SF66 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR B1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;reproductive process#GO:0022414;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;sex differentiation#GO:0007548;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;developmental process involved in reproduction#GO:0003006;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism reproduction#GO:0032504;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;multi-organism process#GO:0051704;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=23212|UniProtKB=Q7Z406 Q7Z406 MYH14 PTHR45615:SF31 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-14 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=11339|UniProtKB=O60225 O60225 SSX5 PTHR14112:SF23 SYNOVIAL SARCOMA, X MEMBER PROTEIN SSX5 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=22394|UniProtKB=Q6ZWB6 Q6ZWB6 KCTD8 PTHR14499:SF68 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD8 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of G protein-coupled receptor signaling pathway#GO:0008277;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15885|UniProtKB=Q9H7V2 Q9H7V2 SYNDIG1 PTHR14768:SF3 UPF0338 PROTEIN SYNAPSE DIFFERENTIATION-INDUCING GENE PROTEIN 1 HUMAN|HGNC=4445|UniProtKB=Q99795 Q99795 GPA33 PTHR44969:SF1 CELL SURFACE A33 ANTIGEN CELL SURFACE A33 ANTIGEN HUMAN|HGNC=4596|UniProtKB=Q14833 Q14833 GRM4 PTHR24060:SF23 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 4 adenylate cyclase activity#GO:0004016;amino acid binding#GO:0016597;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;carboxylic acid binding#GO:0031406;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;glutamate binding#GO:0016595 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=23204|UniProtKB=Q8IZU9 Q8IZU9 KIRREL3 PTHR11640:SF49 NEPHRIN KIN OF IRRE-LIKE PROTEIN 3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell adhesion#GO:0007155;nervous system development#GO:0007399;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;synapse organization#GO:0050808;synapse assembly#GO:0007416;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 intrinsic component of membrane#GO:0031224;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=10258|UniProtKB=P35398 P35398 RORA PTHR45805:SF3 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=17117|UniProtKB=Q9NQQ7 Q9NQQ7 SLC35C2 PTHR11132:SF238 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER C2 secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;anion transport#GO:0006820;pyrimidine nucleotide-sugar transmembrane transport#GO:0090481;carbohydrate derivative transport#GO:1901264 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=25726|UniProtKB=Q9Y4W2 Q9Y4W2 LAS1L PTHR15002:SF0 UNCHARACTERIZED RIBOSOMAL BIOGENESIS PROTEIN LAS1L cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991 HUMAN|HGNC=27260|UniProtKB=Q147U1 Q147U1 ZNF846 PTHR24381:SF345 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 846 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=14517|UniProtKB=Q8N983 Q8N983 MRPL43 PTHR21396:SF2 39S RIBOSOMAL PROTEIN L43 39S RIBOSOMAL PROTEIN L43, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=19980|UniProtKB=Q96EK6 Q96EK6 GNPNAT1 PTHR13355:SF11 GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carbohydrate binding#GO:0030246;N-acyltransferase activity#GO:0016410 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;UDP-N-acetylglucosamine metabolic process#GO:0006047;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;amino sugar metabolic process#GO:0006040;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 acetyltransferase#PC00038 HUMAN|HGNC=7901|UniProtKB=O15130 O15130 NPFF PTHR15044:SF0 NEUROPEPTIDE FF PRO-FMRFAMIDE-RELATED NEUROPEPTIDE FF HUMAN|HGNC=9948|UniProtKB=P46063 P46063 RECQL PTHR13710:SF72 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q1 pyrophosphatase activity#GO:0016462;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA helicase#PC00011 HUMAN|HGNC=9538|UniProtKB=P40306 P40306 PSMB10 PTHR11599:SF41 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-10 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 HUMAN|HGNC=28499|UniProtKB=Q8TAG5 Q8TAG5 VSTM2A PTHR12207:SF23 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2A intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=9138|UniProtKB=Q01780 Q01780 EXOSC10 PTHR12124:SF47 POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED EXOSOME COMPONENT 10 HUMAN|HGNC=121|UniProtKB=O15254 O15254 ACOX3 PTHR10909:SF352 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 3 nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;regulation of biological quality#GO:0065008;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;cellular process#GO:0009987;chemical homeostasis#GO:0048878;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;lipid homeostasis#GO:0055088;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176 HUMAN|HGNC=18486|UniProtKB=O15018 O15018 PDZD2 PTHR11324:SF16 IL16-RELATED PDZ DOMAIN-CONTAINING PROTEIN 2 interleukin superfamily#PC00128 HUMAN|HGNC=16443|UniProtKB=Q5VXU1 Q5VXU1 NKAIN2 PTHR13084:SF3 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 2 localization#GO:0051179;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of transport#GO:0051049;regulation of sodium ion transport#GO:0002028;establishment of localization#GO:0051234;regulation of metal ion transport#GO:0010959;ion transport#GO:0006811;transport#GO:0006810;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of localization#GO:0032879;cation transport#GO:0006812 HUMAN|HGNC=27279|UniProtKB=Q6UWV2 Q6UWV2 MPZL3 PTHR13869:SF20 MYELIN P0 RELATED MYELIN PROTEIN ZERO-LIKE PROTEIN 3 myelin protein#PC00161 HUMAN|HGNC=24083|UniProtKB=Q6UXC1 Q6UXC1 MAMDC4 PTHR23282:SF129 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. APICAL ENDOSOMAL GLYCOPROTEIN HUMAN|HGNC=15585|UniProtKB=Q9HCH5 Q9HCH5 SYTL2 PTHR45716:SF5 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=14455|UniProtKB=P0C5Z0 P0C5Z0 H2AB2 PTHR23430:SF23 HISTONE H2A HISTONE H2A-BBD TYPE 1-RELATED heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=15928|UniProtKB=O00241 O00241 SIRPB1 PTHR19971:SF3 SIGNAL-REGULATORY PROTEIN BETA SIGNAL-REGULATORY PROTEIN BETA-1-RELATED regulation of cell-cell adhesion#GO:0022407;transport#GO:0006810;biological adhesion#GO:0022610;regulation of localization#GO:0032879;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;regulation of vesicle-mediated transport#GO:0060627;leukocyte cell-cell adhesion#GO:0007159;positive regulation of leukocyte activation#GO:0002696;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of leukocyte cell-cell adhesion#GO:1903037;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;lymphocyte activation#GO:0046649;phagocytosis#GO:0006909;positive regulation of immune system process#GO:0002684;vesicle-mediated transport#GO:0016192;cell-cell adhesion#GO:0098609;positive regulation of transport#GO:0051050;cell adhesion#GO:0007155;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of T cell activation#GO:0050870;positive regulation of cell adhesion#GO:0045785;positive regulation of cell activation#GO:0050867;positive regulation of cell-cell adhesion#GO:0022409 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|Gene=HERV-K104|UniProtKB=P63124 P63124 HERV-K104 PTHR19422:SF123 GAG RETROVIRAL POLYPROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 104 PRO PROTEIN viral or transposable element protein#PC00237 HUMAN|HGNC=17804|UniProtKB=Q9P0Z9 Q9P0Z9 PIPOX PTHR10961:SF7 PEROXISOMAL SARCOSINE OXIDASE PEROXISOMAL SARCOSINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 HUMAN|HGNC=28760|UniProtKB=Q9BTT4 Q9BTT4 MED10 PTHR13345:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110 general transcription factor#PC00259 HUMAN|HGNC=20871|UniProtKB=Q5SZJ8 Q5SZJ8 BEND6 PTHR35346:SF1 BEN DOMAIN-CONTAINING PROTEIN 6 BEN DOMAIN-CONTAINING PROTEIN 6 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;transcription corepressor activity#GO:0003714 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of cell differentiation#GO:0045595;regulation of Notch signaling pathway#GO:0008593;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;signaling#GO:0023052;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;positive regulation of neuron differentiation#GO:0045666;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;negative regulation of response to stimulus#GO:0048585;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;negative regulation of signaling#GO:0023057;multicellular organism development#GO:0007275;cell communication#GO:0007154;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;negative regulation of Notch signaling pathway#GO:0045746;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of neurogenesis#GO:0050767;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;generation of neurons#GO:0048699;positive regulation of multicellular organismal process#GO:0051240;Notch signaling pathway#GO:0007219 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=15862|UniProtKB=Q9NWM0 Q9NWM0 SMOX PTHR10742:SF398 FLAVIN MONOAMINE OXIDASE SPERMINE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 HUMAN|HGNC=17789|UniProtKB=Q9NUP9 Q9NUP9 LIN7C PTHR14063:SF5 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG C protein binding#GO:0005515;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell-cell signaling#GO:0007267;signaling#GO:0023052;secretion by cell#GO:0032940;neurotransmitter secretion#GO:0007269;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular macromolecule localization#GO:0070727;signal release from synapse#GO:0099643;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;establishment or maintenance of bipolar cell polarity#GO:0061245;export from cell#GO:0140352 membrane protein complex#GO:0098796;synapse#GO:0045202;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;basolateral plasma membrane#GO:0016323;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell junction protein#PC00070 HUMAN|HGNC=6368|UniProtKB=P49862 P49862 KLK7 PTHR24271:SF45 KALLIKREIN-RELATED KALLIKREIN-7 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=25384|UniProtKB=Q9H069 Q9H069 DRC3 PTHR45973:SF12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED DYNEIN REGULATORY COMPLEX SUBUNIT 3 phosphatase modulator#PC00184 HUMAN|HGNC=18997|UniProtKB=Q96QS6 Q96QS6 PSKH2 PTHR24347:SF255 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE H2 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=12948|UniProtKB=Q9HCG1 Q9HCG1 ZNF160 PTHR24377:SF919 IP01015P-RELATED ZINC FINGER PROTEIN 160 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8518|UniProtKB=Q5XKR4 Q5XKR4 OTP PTHR46770:SF1 HOMEOBOX PROTEIN ORTHOPEDIA HOMEOBOX PROTEIN ORTHOPEDIA homeodomain transcription factor#PC00119 HUMAN|HGNC=26905|UniProtKB=Q8NBZ0 Q8NBZ0 INO80E PTHR21812:SF1 UNCHARACTERIZED INO80 COMPLEX SUBUNIT E membrane-enclosed lumen#GO:0031974;Ino80 complex#GO:0031011;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 HUMAN|HGNC=14440|UniProtKB=Q6P1L5 Q6P1L5 FAM117B PTHR14972:SF6 AGAP011572-PA PROTEIN FAM117B HUMAN|HGNC=12335|UniProtKB=Q13507 Q13507 TRPC3 PTHR10117:SF8 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 3 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 HUMAN|HGNC=29138|UniProtKB=Q9Y6X4 Q9Y6X4 FAM169A PTHR22442:SF3 UNCHARACTERIZED SOLUBLE LAMIN-ASSOCIATED PROTEIN OF 75 KDA HUMAN|HGNC=4586|UniProtKB=Q13224 Q13224 GRIN2B PTHR18966:SF382 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2B amino acid binding#GO:0016597;cation channel activity#GO:0005261;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;neurotransmitter receptor activity#GO:0030594;voltage-gated cation channel activity#GO:0022843;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;glutamate binding#GO:0016595;ligand-gated channel activity#GO:0022834 signal transduction#GO:0007165;chemical synaptic transmission, postsynaptic#GO:0099565;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;integral component of plasma membrane#GO:0005887;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Ionotropic glutamate receptor pathway#P00037>NR2B#P01007;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 HUMAN|HGNC=25547|UniProtKB=Q9P209 Q9P209 CEP72 PTHR23311:SF7 HEAT SHOCK REGULATED 2 CENTROSOMAL PROTEIN OF 72 KDA HUMAN|HGNC=27120|UniProtKB=Q6ZPD9 Q6ZPD9 DPY19L3 PTHR31488:SF4 DPY-19-LIKE 1, LIKE (H. SAPIENS) C-MANNOSYLTRANSFERASE DPY19L3-RELATED transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein mannosylation#GO:0035268;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085;mannosylation#GO:0097502 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=11117|UniProtKB=Q16637 Q16637 SMN2 PTHR13681:SF27 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL MOTOR NEURON PROTEIN cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;SMN-Sm protein complex#GO:0034719;SMN complex#GO:0032797;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=31397|UniProtKB=Q6UWY2 Q6UWY2 PRSS57 PTHR24271:SF55 KALLIKREIN-RELATED SERINE PROTEASE 57 serine protease#PC00203 HUMAN|HGNC=26668|UniProtKB=Q5VTL7 Q5VTL7 FNDC7 PTHR47135:SF1 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7 FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=14250|UniProtKB=Q9H306 Q9H306 MMP27 PTHR10201:SF115 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE-27 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=15188|UniProtKB=Q8NH64 Q8NH64 OR51A7 PTHR26450:SF120 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51A7 transmembrane signal receptor#PC00197 HUMAN|HGNC=26485|UniProtKB=Q96MR6 Q96MR6 CFAP57 PTHR32215:SF0 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57 structural protein#PC00211 HUMAN|HGNC=7531|UniProtKB=Q14764 Q14764 MVP PTHR14165:SF3 MAJOR VAULT PROTEIN MAJOR VAULT PROTEIN cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29500|UniProtKB=Q8N0W3 Q8N0W3 FCSK PTHR32463:SF0 L-FUCOSE KINASE L-FUCOSE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 kinase#PC00137 HUMAN|HGNC=30587|UniProtKB=Q8TAD8 Q8TAD8 SNIP1 PTHR23308:SF36 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 SMAD NUCLEAR-INTERACTING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 HUMAN|HGNC=20815|UniProtKB=Q9Y4C1 Q9Y4C1 KDM3A PTHR12549:SF7 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE 3A nucleic acid binding#GO:0003676;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;catalytic activity, acting on a protein#GO:0140096 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;demethylation#GO:0070988;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;protein demethylation#GO:0006482;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=19957|UniProtKB=O15040 O15040 TECPR2 PTHR23287:SF16 RUBY-EYE2-LIKE PROTEIN TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 2 HUMAN|HGNC=37236|UniProtKB=A8MT33 A8MT33 SYCE1L PTHR21731:SF1 UNCHARACTERIZED SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1-LIKE membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=3017|UniProtKB=Q01658 Q01658 DR1 PTHR46138:SF1 PROTEIN DR1 PROTEIN DR1 nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;core promoter sequence-specific DNA binding#GO:0001046;transcription coactivator activity#GO:0003713;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;TBP-class protein binding#GO:0017025;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;protein binding#GO:0005515 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;RNA polymerase II preinitiation complex assembly#GO:0051123;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA-templated transcription, initiation#GO:0006352;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone acetyltransferase complex#GO:0000123;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=29367|UniProtKB=Q86VY4 Q86VY4 TSPYL5 PTHR11875:SF30 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED-LIKE PROTEIN 5 protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=2510|UniProtKB=P26232 P26232 CTNNA2 PTHR18914:SF23 ALPHA CATENIN CATENIN ALPHA-2 non-motor actin binding protein#PC00165 Alzheimer disease-presenilin pathway#P00004>alpha-catenin#P00133;Wnt signaling pathway#P00057>alpha-catenin#P01471;Cadherin signaling pathway#P00012>alpha-catenin#P00467 HUMAN|HGNC=14974|UniProtKB=Q9Y5X0 Q9Y5X0 SNX10 PTHR46209:SF2 PX DOMAIN-CONTAINING PROTEIN SORTING NEXIN-10 HUMAN|HGNC=390|UniProtKB=O95154 O95154 AKR7A3 PTHR43625:SF11 AFLATOXIN B1 ALDEHYDE REDUCTASE AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 3-RELATED reductase#PC00198 HUMAN|HGNC=8769|UniProtKB=Q9NP92 Q9NP92 MRPS30 PTHR13014:SF3 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S30/P52 PRO-APOTOTIC PROTEIN 39S RIBOSOMAL PROTEIN S30, MITOCHONDRIAL membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=25569|UniProtKB=Q6ZUT1 Q6ZUT1 NKAPD1 PTHR46940:SF1 NKAP DOMAIN-CONTAINING 1 NKAP DOMAIN-CONTAINING 1 HUMAN|HGNC=9164|UniProtKB=Q99719 Q99719 SEPTIN5 PTHR18884:SF68 SEPTIN SEPTIN-5 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;molecular adaptor activity#GO:0060090;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 vesicle fusion#GO:0006906;cellular localization#GO:0051641;cell division#GO:0051301;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;cell cycle process#GO:0022402;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;cytoskeleton-dependent cytokinesis#GO:0061640;vesicle organization#GO:0016050;cytokinesis#GO:0000910;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;membrane fission#GO:0090148;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;export from cell#GO:0140352 presynapse#GO:0098793;synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell division site#GO:0032153;transport vesicle#GO:0030133;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 HUMAN|HGNC=8827|UniProtKB=Q96FA3 Q96FA3 PELI1 PTHR12098:SF4 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 1 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=17558|UniProtKB=O60294 O60294 LCMT2 PTHR46529:SF1 TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4 TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4 tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;RNA methylation#GO:0001510 RNA processing factor#PC00147 HUMAN|HGNC=12185|UniProtKB=P01733 P01733 TRBV12-3 PTHR23268:SF14 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 12-3-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=29823|UniProtKB=P14649 P14649 MYL6B PTHR23048:SF5 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN 6B actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=20690|UniProtKB=Q6IV72 Q6IV72 ZNF425 PTHR24381:SF357 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 425 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28951|UniProtKB=P42331 P42331 ARHGAP25 PTHR15228:SF20 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 25 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;membrane organization#GO:0061024;negative regulation of intracellular signal transduction#GO:1902532;transport#GO:0006810;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;actin filament-based process#GO:0030029;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;negative regulation of small GTPase mediated signal transduction#GO:0051058;vesicle organization#GO:0016050;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;phagocytosis#GO:0006909;regulation of GTPase activity#GO:0043087;endocytosis#GO:0006897;negative regulation of signaling#GO:0023057;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;localization#GO:0051179;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;actin cytoskeleton organization#GO:0030036 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=23328|UniProtKB=Q6P2D0 Q6P2D0 ZFP1 PTHR24377:SF248 IP01015P-RELATED ZINC FINGER PROTEIN 1 HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28648|UniProtKB=Q8IYB7 Q8IYB7 DIS3L2 PTHR23355:SF9 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 2 exoribonuclease#PC00099 HUMAN|HGNC=10726|UniProtKB=O95025 O95025 SEMA3D PTHR11036:SF36 SEMAPHORIN SEMAPHORIN-3D receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=30414|UniProtKB=Q9BVK8 Q9BVK8 TMEM147 PTHR12869:SF0 SMALL SEVEN TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE PROTEIN 147 HUMAN|HGNC=15476|UniProtKB=P63167 P63167 DYNLL1 PTHR11886:SF84 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 1, CYTOPLASMIC protein binding#GO:0005515;binding#GO:0005488 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;microtubule cytoskeleton organization#GO:0000226;regulation of catalytic activity#GO:0050790;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;positive regulation of catalytic activity#GO:0043085;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=7460|UniProtKB=P03901 P03901 MT-ND4L PTHR11434:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4L oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;membrane#GO:0016020;NADH dehydrogenase complex#GO:0030964;catalytic complex#GO:1902494 oxidoreductase#PC00176 HUMAN|HGNC=18658|UniProtKB=Q92621 Q92621 NUP205 PTHR31344:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP205 NUCLEAR PORE COMPLEX PROTEIN NUP205 HUMAN|HGNC=25392|UniProtKB=Q3ZCX4 Q3ZCX4 ZNF568 PTHR24377:SF866 IP01015P-RELATED ZINC FINGER PROTEIN 568 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26303|UniProtKB=Q8TE99 Q8TE99 PXYLP1 PTHR11567:SF125 ACID PHOSPHATASE-RELATED 2-PHOSPHOXYLOSE PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;chondroitin sulfate proteoglycan metabolic process#GO:0050654;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=29550|UniProtKB=Q9NPQ8 Q9NPQ8 RIC8A PTHR12425:SF4 SYNEMBRYN SYNEMBRYN-A GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 HUMAN|HGNC=17166|UniProtKB=Q86VR8 Q86VR8 FJX1 PTHR13147:SF5 FOUR-JOINTED BOX PROTEIN 1 FOUR-JOINTED BOX PROTEIN 1 cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=12657|UniProtKB=P15498 P15498 VAV1 PTHR45818:SF2 PROTEIN VAV PROTO-ONCOGENE VAV B cell activation#P00010>vav#P00368;T cell activation#P00053>vav#P01295;PDGF signaling pathway#P00047>Vav#P01169;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GEF#P00875 HUMAN|HGNC=25266|UniProtKB=Q8WVZ9 Q8WVZ9 KBTBD7 PTHR24412:SF23 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 HUMAN|HGNC=24128|UniProtKB=Q9BRN9 Q9BRN9 TM2D3 PTHR21016:SF7 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=28947|UniProtKB=Q50LG9 Q50LG9 LRRC24 PTHR24373:SF269 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 24 cell surface#GO:0009986;extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=5427|UniProtKB=P05013 P05013 IFNA6 PTHR11691:SF27 TYPE I INTERFERON INTERFERON ALPHA-6 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=26262|UniProtKB=Q6NXR4 Q6NXR4 TTI2 PTHR32226:SF2 TELO2-INTERACTING PROTEIN 2 TELO2-INTERACTING PROTEIN 2 membrane-enclosed lumen#GO:0031974;microtubule organizing center#GO:0005815;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;centriole#GO:0005814;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856 HUMAN|HGNC=15589|UniProtKB=Q8TDW5 Q8TDW5 SYTL5 PTHR45716:SF6 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 5 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=9702|UniProtKB=Q96QR8 Q96QR8 PURB PTHR12611:SF4 PUR-TRANSCRIPTIONAL ACTIVATOR TRANSCRIPTIONAL ACTIVATOR PROTEIN PUR-BETA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=20508|UniProtKB=Q8IUE6 Q8IUE6 H2AC21 PTHR23430:SF72 HISTONE H2A HISTONE H2A TYPE 2-B heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=14948|UniProtKB=Q96I51 Q96I51 RCC1L PTHR46337:SF1 RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN HUMAN|HGNC=19308|UniProtKB=Q58EX2 Q58EX2 SDK2 PTHR13817:SF59 TITIN PROTEIN SIDEKICK-2 HUMAN|HGNC=22970|UniProtKB=P60409 P60409 KRTAP10-7 PTHR23262:SF227 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-4-RELATED HUMAN|HGNC=20039|UniProtKB=P40123 P40123 CAP2 PTHR10652:SF2 ADENYLYL CYCLASE-ASSOCIATED PROTEIN ADENYLYL CYCLASE-ASSOCIATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;enzyme binding#GO:0019899;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 regulation of lyase activity#GO:0051339;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular process#GO:0009987;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=2557|UniProtKB=P39880 P39880 CUX1 PTHR14043:SF4 CCAAT DISPLACEMENT PROTEIN-RELATED HOMEOBOX PROTEIN CUT-LIKE 1 homeodomain transcription factor#PC00119 HUMAN|HGNC=44438|UniProtKB=C9JJH3 C9JJH3 USP17L10 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=19701|UniProtKB=Q8WXI2 Q8WXI2 CNKSR2 PTHR12844:SF21 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 2 HUMAN|HGNC=20819|UniProtKB=Q86XQ3 Q86XQ3 CATSPER3 PTHR47131:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3 CATION CHANNEL SPERM-ASSOCIATED PROTEIN 3 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 male gamete generation#GO:0048232;cellular process involved in reproduction in multicellular organism#GO:0022412;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;sperm motility#GO:0097722;spermatid differentiation#GO:0048515;cation transport#GO:0006812;cilium movement involved in cell motility#GO:0060294;cell differentiation#GO:0030154;establishment of localization#GO:0051234;spermatogenesis#GO:0007283;reproductive process#GO:0022414;flagellated sperm motility#GO:0030317;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;sperm capacitation#GO:0048240;germ cell development#GO:0007281;cellular developmental process#GO:0048869;monovalent inorganic cation transport#GO:0015672;gamete generation#GO:0007276;metal ion transport#GO:0030001;multicellular organism reproduction#GO:0032504;ion transport#GO:0006811;cilium or flagellum-dependent cell motility#GO:0001539;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;multi-organism process#GO:0051704;cilium movement#GO:0003341;localization#GO:0051179;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;cilium-dependent cell motility#GO:0060285;spermatid development#GO:0007286;sodium ion transport#GO:0006814;reproduction#GO:0000003;microtubule-based process#GO:0007017;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011 membrane protein complex#GO:0098796;acrosomal vesicle#GO:0001669;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;secretory granule#GO:0030141;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cation channel complex#GO:0034703;cytoplasm#GO:0005737;voltage-gated calcium channel complex#GO:0005891;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;CatSper complex#GO:0036128;endomembrane system#GO:0012505;intracellular#GO:0005622;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=30035|UniProtKB=Q8WYR1 Q8WYR1 PIK3R5 PTHR15593:SF2 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 5 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 PDGF signaling pathway#P00047>PI3K#P01168;PI3 kinase pathway#P00048>p101#P01203;Axon guidance mediated by netrin#P00009>PI3K#P00363;EGF receptor signaling pathway#P00018>PI3K#P00557;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900 HUMAN|HGNC=28974|UniProtKB=Q14166 Q14166 TTLL12 PTHR46088:SF1 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 HUMAN|HGNC=25892|UniProtKB=Q5VU57 Q5VU57 AGBL4 PTHR12756:SF9 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 6 metalloprotease#PC00153 HUMAN|HGNC=13572|UniProtKB=Q9Y6R7 Q9Y6R7 FCGBP PTHR11339:SF244 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED IGGFC-BINDING PROTEIN extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=18549|UniProtKB=Q9H295 Q9H295 DCSTAMP PTHR21041:SF2 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN HUMAN|HGNC=7971|UniProtKB=P13056 P13056 NR2C1 PTHR24083:SF49 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=18938|UniProtKB=Q7Z4W3 Q7Z4W3 KRTAP19-3 PTHR38140:SF5 KERATIN-ASSOCIATED PROTEIN 19-3-RELATED KERATIN-ASSOCIATED PROTEIN 19-3-RELATED HUMAN|HGNC=6461|UniProtKB=Q9NSB2 Q9NSB2 KRT84 PTHR45616:SF17 FAMILY NOT NAMED KERATIN, TYPE II CUTICULAR HB4 HUMAN|HGNC=26991|UniProtKB=Q6IEE7 Q6IEE7 TMEM132E PTHR13388:SF7 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 132E HUMAN|HGNC=18124|UniProtKB=Q9H244 Q9H244 P2RY12 PTHR24233:SF0 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 12 nucleotide binding#GO:0000166;signaling receptor activity#GO:0038023;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=16690|UniProtKB=Q6PEY0 Q6PEY0 GJB7 PTHR11984:SF26 CONNEXIN GAP JUNCTION BETA-7 PROTEIN gap junction#PC00105 HUMAN|HGNC=9567|UniProtKB=O00233 O00233 PSMD9 PTHR12651:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 proteasome assembly#GO:0043248;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 HUMAN|HGNC=18290|UniProtKB=Q8NFW8 Q8NFW8 CMAS PTHR21485:SF3 HAD SUPERFAMILY MEMBERS CMAS AND KDSC N-ACYLNEURAMINATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 nucleotidyltransferase#PC00174 HUMAN|HGNC=20261|UniProtKB=Q9BVL2 Q9BVL2 NUP58 PTHR13437:SF2 NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1 NUCLEOPORIN P58/P45 signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=23719|UniProtKB=Q96FM1 Q96FM1 PGAP3 PTHR13148:SF0 PER1-RELATED POST-GPI ATTACHMENT TO PROTEINS FACTOR 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=25502|UniProtKB=Q9NUP7 Q9NUP7 TRMT13 PTHR12998:SF0 UNCHARACTERIZED TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=19369|UniProtKB=Q8NEY8 Q8NEY8 PPHLN1 PTHR15836:SF4 PERIPHILIN 1 PERIPHILIN-1 HUMAN|HGNC=23383|UniProtKB=Q9HCK0 Q9HCK0 ZBTB26 PTHR24399:SF14 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 26 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=2289|UniProtKB=O14548 O14548 COX7A2L PTHR10510:SF2 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A-RELATED PROTEIN, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular component biogenesis#GO:0044085;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;protein-containing complex subunit organization#GO:0043933;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;regulation of phosphorylation#GO:0042325;nucleoside phosphate biosynthetic process#GO:1901293;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;regulation of phosphate metabolic process#GO:0019220;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;organelle organization#GO:0006996;oxidative phosphorylation#GO:0006119;biological regulation#GO:0065007;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227 oxidase#PC00175 HUMAN|HGNC=9182|UniProtKB=Q9UNA4 Q9UNA4 POLI PTHR46404:SF1 DNA POLYMERASE IOTA DNA POLYMERASE IOTA DNA metabolism protein#PC00009 HUMAN|HGNC=27291|UniProtKB=Q8IX19 Q8IX19 MCEMP1 PTHR37856:SF1 MAST CELL-EXPRESSED MEMBRANE PROTEIN 1 MAST CELL-EXPRESSED MEMBRANE PROTEIN 1 HUMAN|HGNC=19977|UniProtKB=Q96NR8 Q96NR8 RDH12 PTHR24320:SF246 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 12 dehydrogenase#PC00092 HUMAN|HGNC=32044|UniProtKB=Q5JVX7 Q5JVX7 C1orf141 PTHR36873:SF1 HYPOTHETICAL GENE SUPPORTED BY BC079057 HYPOTHETICAL GENE SUPPORTED BY BC079057 HUMAN|HGNC=28359|UniProtKB=Q9H6F5 Q9H6F5 CCDC86 PTHR13557:SF1 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 86 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=15225|UniProtKB=Q8NGK5 Q8NGK5 OR52M1 PTHR26450:SF136 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52M1 transmembrane signal receptor#PC00197 HUMAN|HGNC=21586|UniProtKB=Q8NG68 Q8NG68 TTL PTHR46570:SF1 TUBULIN--TYROSINE LIGASE TUBULIN--TYROSINE LIGASE HUMAN|HGNC=16682|UniProtKB=Q86T24 Q86T24 ZBTB33 PTHR24399:SF24 ZINC FINGER AND BTB DOMAIN-CONTAINING TRANSCRIPTIONAL REGULATOR KAISO cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=20625|UniProtKB=M0R2J8 M0R2J8 DCDC1 PTHR46302:SF3 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 1 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=2590|UniProtKB=P05108 P05108 CYP11A1 PTHR24279:SF3 FAMILY NOT NAMED CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME, MITOCHONDRIAL sterol metabolic process#GO:0016125;lipid metabolic process#GO:0006629;response to peptide hormone#GO:0043434;cholesterol metabolic process#GO:0008203;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular response to nitrogen compound#GO:1901699;steroid metabolic process#GO:0008202;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biological quality#GO:0065008;secondary alcohol metabolic process#GO:1902652;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;hormone biosynthetic process#GO:0042446;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular response to peptide#GO:1901653;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;regulation of hormone levels#GO:0010817;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;steroid biosynthetic process#GO:0006694;small molecule metabolic process#GO:0044281 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=8806|UniProtKB=P08559 P08559 PDHA1 PTHR11516:SF52 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA, SOMATIC FORM, MITOCHONDRIAL membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;oxidoreductase complex#GO:1990204;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092 TCA cycle#P00051>Pyruvate Dehydrogenase#P01266;Pyruvate metabolism#P02772>Pyruvate Dehydrogenase#P03133 HUMAN|HGNC=10903|UniProtKB=Q13291 Q13291 SLAMF1 PTHR12080:SF49 SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=26725|UniProtKB=Q9P272 Q9P272 TRMT9B PTHR13069:SF36 UNCHARACTERIZED TRNA METHYLTRANSFERASE 9B-RELATED tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;methyltransferase activity#GO:0008168;oxidoreductase activity#GO:0016491;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;dioxygenase activity#GO:0051213;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=23788|UniProtKB=Q6NUP7 Q6NUP7 PPP4R4 PTHR21467:SF0 PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 PPP4R4 SERINE/THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 phosphatase modulator#PC00184 HUMAN|HGNC=29656|UniProtKB=Q8WUY1 Q8WUY1 THEM6 PTHR12475:SF4 FAMILY NOT NAMED PROTEIN THEM6 HUMAN|HGNC=29824|UniProtKB=Q96A32 Q96A32 MYLPF PTHR23049:SF10 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2, SKELETAL MUSCLE ISOFORM actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=7056|UniProtKB=O60502 O60502 OGA PTHR13170:SF16 O-GLCNACASE PROTEIN O-GLCNACASE hydrolase#PC00121 HUMAN|HGNC=18007|UniProtKB=Q9H4G4 Q9H4G4 GLIPR2 PTHR10334:SF517 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|Ensembl=ENSG00000235118|UniProtKB=A0A1B0GTK4 A0A1B0GTK4 FAM237A PTHR36690:SF2 PROTEIN FAM237A PROTEIN FAM237A HUMAN|HGNC=7467|UniProtKB=P55157 P55157 MTTP PTHR13024:SF1 MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN, LARGE SUBUNIT MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN LARGE SUBUNIT phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;lipoprotein metabolic process#GO:0042157;chemical homeostasis#GO:0048878;protein metabolic process#GO:0019538;cholesterol homeostasis#GO:0042632;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;basolateral plasma membrane#GO:0016323;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=29335|UniProtKB=Q3SXP7 Q3SXP7 SHISAL1 PTHR31395:SF11 SHISA PROTEIN SHISA-LIKE-1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=39552|UniProtKB=Q5W188 Q5W188 CST9LP1 PTHR46945:SF2 CYSTATIN-9-LIKE CYSTATIN-9-LIKE PROTEIN CST9LP1-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=24519|UniProtKB=Q6NUS6 Q6NUS6 TCTN3 PTHR14611:SF4 TECTONIC FAMILY MEMBER TECTONIC-3 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;smoothened signaling pathway#GO:0007224;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;signal transduction#GO:0007165;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;signaling#GO:0023052;cellular response to stimulus#GO:0051716;vesicle localization#GO:0051648;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;response to stimulus#GO:0050896;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 HUMAN|HGNC=4089|UniProtKB=O00591 O00591 GABRP PTHR18945:SF33 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT PI signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;system process#GO:0003008;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=14921|UniProtKB=Q9NYV7 Q9NYV7 TAS2R16 PTHR11394:SF68 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 16 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=8886|UniProtKB=P0DJD7 P0DJD7 PGA4 PTHR47966:SF22 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED PEPSIN A-3-RELATED HUMAN|HGNC=1040|UniProtKB=Q12934 Q12934 BFSP1 PTHR14069:SF0 FILENSIN FILENSIN structural molecule activity#GO:0005198 cellular developmental process#GO:0048869;epithelium development#GO:0060429;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;cell development#GO:0048468;cell differentiation#GO:0030154;system development#GO:0048731;anatomical structure development#GO:0048856;eye development#GO:0001654;lens development in camera-type eye#GO:0002088;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intracellular#GO:0005622;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 HUMAN|HGNC=7082|UniProtKB=P14209 P14209 CD99 PTHR15076:SF15 CD99/MIC2 PROTEIN RELATED CD99 ANTIGEN regulation of locomotion#GO:0040012;biological adhesion#GO:0022610;regulation of localization#GO:0032879;homotypic cell-cell adhesion#GO:0034109;positive regulation of cellular component movement#GO:0051272;positive regulation of leukocyte migration#GO:0002687;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;granulocyte migration#GO:0097530;regulation of cell migration#GO:0030334;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;myeloid leukocyte migration#GO:0097529;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;neutrophil migration#GO:1990266;localization of cell#GO:0051674;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;immune system process#GO:0002376;positive regulation of cell migration#GO:0030335;lymphocyte migration#GO:0072676;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=8232|UniProtKB=Q96R48 Q96R48 OR2A5 PTHR26453:SF232 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2A5 transmembrane signal receptor#PC00197 HUMAN|HGNC=6842|UniProtKB=P36507 P36507 MAP2K2 PTHR48013:SF8 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>MKK2#P01368;EGF receptor signaling pathway#P00018>MEK1-2#P00559;Gonadotropin-releasing hormone receptor pathway#P06664>MEK1/2#P06739;VEGF signaling pathway#P00056>MEK#P01402;T cell activation#P00053>MEK#P01312;Gonadotropin-releasing hormone receptor pathway#P06664>MAP2K1/2#P06794;FGF signaling pathway#P00021>MEK1-2#P00642;B cell activation#P00010>MEK#P00383;Toll receptor signaling pathway#P00054>MKK1#P01369;Ras Pathway#P04393>MEK#P04557;Integrin signalling pathway#P00034>MEK#P00925;PDGF signaling pathway#P00047>MEK#P01162;Integrin signalling pathway#P00034>ERK#P00907;Angiogenesis#P00005>MEK#P00225;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>MEK#P05926;CCKR signaling map#P06959>MAP2K2#P07121;Endothelin signaling pathway#P00019>MEK#P00572;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 HUMAN|HGNC=4666|UniProtKB=Q9Y5Q9 Q9Y5Q9 GTF3C3 PTHR23082:SF0 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;transcription by RNA polymerase III#GO:0006383;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127 general transcription factor#PC00259 HUMAN|HGNC=29972|UniProtKB=Q8NHQ1 Q8NHQ1 CEP70 PTHR14594:SF1 CENTROSOMAL PROTEIN OF 70 KDA CENTROSOMAL PROTEIN OF 70 KDA intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=11972|UniProtKB=O15405 O15405 TOX3 PTHR45781:SF3 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 3 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26575|UniProtKB=Q96LW4 Q96LW4 PRIMPOL PTHR31399:SF0 DNA-DIRECTED PRIMASE / POLYMERASE PROTEIN DNA-DIRECTED PRIMASE/POLYMERASE PROTEIN catalytic activity, acting on RNA#GO:0140098;DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;cellular nitrogen compound biosynthetic process#GO:0044271;replication fork processing#GO:0031297;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;response to UV#GO:0009411;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=5601|UniProtKB=A0A0C4DH36 A0A0C4DH36 IGHV3-38 PTHR23266:SF204 IMMUNOGLOBULIN HEAVY CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=1917|UniProtKB=O14647 O14647 CHD2 PTHR45623:SF19 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 2 HUMAN|HGNC=24716|UniProtKB=Q5U651 Q5U651 RASIP1 PTHR16027:SF4 DILUTE DOMAIN-CONTAINING PROTEIN YPR089W RAS-INTERACTING PROTEIN 1 HUMAN|HGNC=5041|UniProtKB=P31943 P31943 HNRNPH1 PTHR13976:SF60 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=20869|UniProtKB=O95393 O95393 BMP10 PTHR11848:SF39 TGF-BETA FAMILY BONE MORPHOGENETIC PROTEIN 10 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=9158|UniProtKB=Q8ND90 Q8ND90 PNMA1 PTHR23095:SF17 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN MA1 HUMAN|HGNC=24788|UniProtKB=Q1L5Z9 Q1L5Z9 LONRF2 PTHR23327:SF5 RING FINGER PROTEIN 127 LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 2 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=24741|UniProtKB=Q8NAN2 Q8NAN2 MIGA1 PTHR21508:SF3 MITOGUARDIN MITOGUARDIN 1 mitochondrial fusion#GO:0008053;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;organelle fusion#GO:0048284 HUMAN|HGNC=34005|UniProtKB=A8CG34 A8CG34 POM121C PTHR23193:SF5 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR ENVELOPE PORE MEMBRANE PROTEIN POM 121C-RELATED signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=33731|UniProtKB=A6NLC5 A6NLC5 C3orf70 PTHR31785:SF2 UPF0524 PROTEIN C3ORF70 UPF0524 PROTEIN C3ORF70 HUMAN|HGNC=30943|UniProtKB=O00488 O00488 ZNF593 PTHR46095:SF1 ZINC FINGER PROTEIN 593 ZINC FINGER PROTEIN 593 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6782|UniProtKB=O60675 O60675 MAFK PTHR10129:SF26 TRANSCRIPTION FACTOR MAF TRANSCRIPTION FACTOR MAFK cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=12299|UniProtKB=P34981 P34981 TRHR PTHR46061:SF2 THYROTROPIN-RELEASING HORMONE RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;positive regulation of phospholipase activity#GO:0010518;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of hydrolase activity#GO:0051345;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;G protein-coupled receptor signaling pathway#GO:0007186;activation of phospholipase C activity#GO:0007202;intracellular signal transduction#GO:0035556;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863 C4 zinc finger nuclear receptor#PC00169 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH Receptor#P04580 HUMAN|Gene=B3GNT10|UniProtKB=A8MXE2 A8MXE2 - PTHR11214:SF29 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE LOC100288842-RELATED transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;cellular polysaccharide biosynthetic process#GO:0033692;cellular polysaccharide metabolic process#GO:0044264;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=25754|UniProtKB=Q9H9H4 Q9H9H4 VPS37B PTHR13678:SF9 WILLIAMS-BEUREN SYNDROME CRITICAL REGION PROTEIN-RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37B protein catabolic process in the vacuole#GO:0007039;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;multivesicular body sorting pathway#GO:0071985;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;cellular protein catabolic process#GO:0044257;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=14293|UniProtKB=Q9BXF9 Q9BXF9 TEKT3 PTHR19960:SF24 TEKTIN TEKTIN-3 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;cilium movement involved in cell motility#GO:0060294;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;B axonemal microtubule#GO:0097650;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;nucleus#GO:0005634;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=25959|UniProtKB=Q9NXP7 Q9NXP7 GIN1 PTHR46148:SF3 CHROMO DOMAIN-CONTAINING PROTEIN GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 HUMAN|HGNC=10932|UniProtKB=Q9Y2C5 Q9Y2C5 SLC17A4 PTHR11662:SF284 SOLUTE CARRIER FAMILY 17 SMALL INTESTINE URATE EXPORTER-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=11936|UniProtKB=P48023 P48023 FASLG PTHR11471:SF33 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 6 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;apoptotic signaling pathway#GO:0097190;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;cell death#GO:0008219;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 FAS signaling pathway#P00020>FasL#P00617;Apoptosis signaling pathway#P00006>FAS ligand#P00326 HUMAN|HGNC=28766|UniProtKB=Q8N823 Q8N823 ZNF611 PTHR24377:SF741 IP01015P-RELATED ZINC FINGER PROTEIN 611 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=29265|UniProtKB=Q9P2G4 Q9P2G4 MAP10 PTHR21831:SF2 UNCHARACTERIZED MICROTUBULE-ASSOCIATED PROTEIN 10 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;cell division#GO:0051301;mitotic spindle organization#GO:0007052;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;positive regulation of cell cycle#GO:0045787;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of cell division#GO:0051302;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;positive regulation of cell cycle process#GO:0090068;supramolecular fiber organization#GO:0097435;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;spindle organization#GO:0007051;positive regulation of biological process#GO:0048518;cytokinesis#GO:0000910;regulation of cytokinesis#GO:0032465;cytoplasmic microtubule organization#GO:0031122;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;membrane fission#GO:0090148;positive regulation of cytokinesis#GO:0032467;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;positive regulation of cell division#GO:0051781;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285 supramolecular complex#GO:0099080;spindle pole#GO:0000922;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;mitotic spindle midzone#GO:1990023;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;intracellular#GO:0005622;midbody#GO:0030496;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 HUMAN|HGNC=9184|UniProtKB=Q9UGP5 Q9UGP5 POLL PTHR11276:SF28 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE LAMBDA transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;DNA polymerase activity#GO:0034061;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-directed DNA polymerase#PC00018 HUMAN|HGNC=25960|UniProtKB=Q9H1M0 Q9H1M0 NUP62CL PTHR12084:SF11 NUCLEAR PORE GLYCOPROTEIN P62-RELATED NUCLEOPORIN-62 C-TERMINAL-LIKE PROTEIN lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;structural molecule activity#GO:0005198;phospholipid binding#GO:0005543;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;nuclear pore central transport channel#GO:0044613;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=19765|UniProtKB=Q8WXK3 Q8WXK3 ASB13 PTHR24173:SF44 FAMILY NOT NAMED ANKYRIN REPEAT AND SOCS BOX PROTEIN 13 HUMAN|HGNC=6839|UniProtKB=P11137 P11137 MAP2 PTHR11501:SF15 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;neuron development#GO:0048666;generation of neurons#GO:0048699 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=23567|UniProtKB=Q96EQ0 Q96EQ0 SGTB PTHR45831:SF1 LD24721P SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN BETA molecular adaptor activity#GO:0060090;binding#GO:0005488 cellular localization#GO:0051641;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;posttranslational protein targeting to endoplasmic reticulum membrane#GO:0006620;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;establishment of protein localization to endoplasmic reticulum#GO:0072599;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;protein localization to endoplasmic reticulum#GO:0070972;chaperone-mediated protein folding#GO:0061077;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;cellular macromolecule localization#GO:0070727;response to stress#GO:0006950;regulation of cellular process#GO:0050794;protein transport#GO:0015031;intracellular transport#GO:0046907;cellular response to stress#GO:0033554;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;organonitrogen compound catabolic process#GO:1901565;amide transport#GO:0042886;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;protein localization to membrane#GO:0072657;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;protein targeting to membrane#GO:0006612;response to chemical#GO:0042221;protein folding#GO:0006457;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;ubiquitin-dependent ERAD pathway#GO:0030433;intracellular protein transport#GO:0006886;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=7397|UniProtKB=P04732 P04732 MT1E PTHR23299:SF48 METALLOTHIONEIN METALLOTHIONEIN-1E-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;transition metal ion homeostasis#GO:0055076;response to metal ion#GO:0010038;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;response to toxic substance#GO:0009636;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28235|UniProtKB=Q96IU4 Q96IU4 ABHD14B PTHR46197:SF2 PROTEIN ABHD14B-LIKE PROTEIN ABHD14B cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=20166|UniProtKB=O15037 O15037 KHNYN PTHR12876:SF28 N4BP1-RELATED PROTEIN KHNYN catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 endoribonuclease#PC00094 HUMAN|HGNC=13097|UniProtKB=Q06732 Q06732 ZNF33B PTHR24376:SF193 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 33B-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29604|UniProtKB=P0DP58 P0DP58 LYNX1 PTHR16983:SF27 UPAR/LY6 DOMAIN-CONTAINING PROTEIN LY-6/NEUROTOXIN-LIKE PROTEIN 1 cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;receptor regulator activity#GO:0030545;acetylcholine receptor activity#GO:0015464;molecular function regulator#GO:0098772;molecular transducer activity#GO:0060089;acetylcholine receptor regulator activity#GO:0030548;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;acetylcholine binding#GO:0042166;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 HUMAN|HGNC=26456|UniProtKB=Q96N23 Q96N23 CFAP54 PTHR33487:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 54 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 54 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 structural protein#PC00211 HUMAN|HGNC=2018|UniProtKB=Q14CN2 Q14CN2 CLCA4 PTHR10579:SF2 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=7641|UniProtKB=P54920 P54920 NAPA PTHR13768:SF23 SOLUBLE NSF ATTACHMENT PROTEIN SNAP ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN syntaxin binding#GO:0019905;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of neurotransmitter secretion#GO:0046928;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;secretion#GO:0046903;regulation of secretion#GO:0051046;synaptic signaling#GO:0099536;regulation of exocytosis#GO:0017157;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of cellular localization#GO:0060341;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;protein transport#GO:0015031;regulation of trans-synaptic signaling#GO:0099177;intracellular transport#GO:0046907;export from cell#GO:0140352;vesicle fusion#GO:0006906;cellular protein complex disassembly#GO:0043624;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of signaling#GO:0023051;transport#GO:0006810;protein-containing complex assembly#GO:0065003;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular component disassembly#GO:0022411;regulation of protein-containing complex assembly#GO:0043254;regulation of transport#GO:0051049;neurotransmitter transport#GO:0006836;signal release#GO:0023061;vesicle organization#GO:0016050;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;cellular process#GO:0009987;localization#GO:0051179;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;synaptic transmission, glutamatergic#GO:0035249;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;cell junction#GO:0030054;SNARE complex#GO:0031201;vacuole#GO:0005773;terminal bouton#GO:0043195;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;axon#GO:0030424;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=8906|UniProtKB=Q96G03 Q96G03 PGM2 PTHR45745:SF3 PHOSPHOMANNOMUTASE 45A PHOSPHOGLUCOMUTASE-2 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 mutase#PC00160 HUMAN|HGNC=14766|UniProtKB=Q8NGJ3 Q8NGJ3 OR52E1 PTHR26450:SF3 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E1 transmembrane signal receptor#PC00197 HUMAN|HGNC=6472|UniProtKB=O00515 O00515 LAD1 PTHR12392:SF0 LADININ 1 LADININ-1 structural protein#PC00211 HUMAN|HGNC=19959|UniProtKB=Q9Y4F4 Q9Y4F4 TOGARAM1 PTHR21567:SF6 CLASP TOG ARRAY REGULATOR OF AXONEMAL MICROTUBULES PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=11772|UniProtKB=P36897 P36897 TGFBR1 PTHR23255:SF61 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-1 signaling receptor activity#GO:0038023;SMAD binding#GO:0046332;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;protein binding#GO:0005515;activin binding#GO:0048185;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 heart development#GO:0007507;signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;developmental process#GO:0032502;protein modification process#GO:0036211;transforming growth factor beta receptor signaling pathway#GO:0007179;nervous system development#GO:0007399;phosphorus metabolic process#GO:0006793;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 HUMAN|HGNC=11939|UniProtKB=P41273 P41273 TNFSF9 PTHR15153:SF0 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 9 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 9 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;tumor necrosis factor receptor superfamily binding#GO:0032813;cytokine receptor binding#GO:0005126 regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;mononuclear cell proliferation#GO:0032943;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;immune system development#GO:0002520;cell adhesion#GO:0007155;positive regulation of T cell differentiation#GO:0045582;T cell differentiation#GO:0030217;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;positive regulation of multicellular organismal process#GO:0051240;animal organ development#GO:0048513;biological adhesion#GO:0022610;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;positive regulation of T cell proliferation#GO:0042102;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;leukocyte cell-cell adhesion#GO:0007159;cell differentiation#GO:0030154;system development#GO:0048731;T cell proliferation#GO:0042098;regulation of hemopoiesis#GO:1903706;positive regulation of leukocyte cell-cell adhesion#GO:1903039;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;regulation of cell population proliferation#GO:0042127;positive regulation of cell differentiation#GO:0045597;lymphocyte activation#GO:0046649;multicellular organism development#GO:0007275;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;regulation of T cell proliferation#GO:0042129;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;lymphocyte differentiation#GO:0030098;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;regulation of leukocyte proliferation#GO:0070663;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=16178|UniProtKB=P59826 P59826 BPIFB3 PTHR46019:SF5 BPI FOLD-CONTAINING FAMILY B MEMBER 4-RELATED BPI FOLD-CONTAINING FAMILY B MEMBER 3 HUMAN|HGNC=26264|UniProtKB=Q8IWF2 Q8IWF2 FOXRED2 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 oxygenase#PC00177 HUMAN|HGNC=4336|UniProtKB=P49448 P49448 GLUD2 PTHR11606:SF15 GLUTAMATE DEHYDROGENASE GLUTAMATE DEHYDROGENASE 2, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 HUMAN|HGNC=1081|UniProtKB=Q01954 Q01954 BNC1 PTHR15021:SF1 DISCONNECTED-RELATED ZINC FINGER PROTEIN BASONUCLIN-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;transcription by RNA polymerase I#GO:0006360;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=26950|UniProtKB=Q1ZYL8 Q1ZYL8 IZUMO4 PTHR37357:SF1 IZUMO SPERM-EGG FUSION PROTEIN 4 IZUMO SPERM-EGG FUSION PROTEIN 4 HUMAN|HGNC=17209|UniProtKB=Q9NRP7 Q9NRP7 STK36 PTHR22983:SF6 PROTEIN KINASE RELATED SERINE/THREONINE-PROTEIN KINASE 36 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>MEK1-2#P00559;PDGF signaling pathway#P00047>MAPKAPK2#P01157;FGF signaling pathway#P00021>MEK1-2#P00642;Hedgehog signaling pathway#P00025>Fused#P00686 HUMAN|HGNC=1546|UniProtKB=P50454 P50454 SERPINH1 PTHR11461:SF27 SERINE PROTEASE INHIBITOR, SERPIN SERPIN H1 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;supramolecular fiber organization#GO:0097435;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;collagen fibril organization#GO:0030199;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;extracellular structure organization#GO:0043062;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protease inhibitor#PC00191 HUMAN|HGNC=28316|UniProtKB=Q8TCD6 Q8TCD6 PHOSPHO2 PTHR20889:SF1 PHOSPHATASE, ORPHAN 1, 2 PYRIDOXAL PHOSPHATE PHOSPHATASE PHOSPHO2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181 HUMAN|HGNC=25591|UniProtKB=Q86WR0 Q86WR0 CCDC25 PTHR13049:SF8 DUF814-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 25 HUMAN|HGNC=27411|UniProtKB=Q6PIF2 Q6PIF2 SYCE2 PTHR28398:SF1 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 2 SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 2 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;synaptonemal complex#GO:0000795 HUMAN|HGNC=27039|UniProtKB=Q86Y79 Q86Y79 PTRH1 PTHR17224:SF1 PEPTIDYL-TRNA HYDROLASE PEPTIDYL-TRNA HYDROLASE-RELATED carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 esterase#PC00097 HUMAN|HGNC=1513|UniProtKB=O14958 O14958 CASQ2 PTHR10033:SF15 CALSEQUESTRIN CALSEQUESTRIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;regulation of muscle contraction#GO:0006937;calcium-mediated signaling#GO:0019722;divalent inorganic cation homeostasis#GO:0072507;regulation of metal ion transport#GO:0010959;system process#GO:0003008;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;intracellular signal transduction#GO:0035556;cellular cation homeostasis#GO:0030003;regulation of transmembrane transport#GO:0034762;regulation of multicellular organismal process#GO:0051239;regulation of heart contraction#GO:0008016;calcium ion transmembrane transport#GO:0070588;regulation of release of sequestered calcium ion into cytosol#GO:0051279;heart contraction#GO:0060047;regulation of calcium ion transport#GO:0051924;release of sequestered calcium ion into cytosol#GO:0051209;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cellular localization#GO:0060341;regulation of cytosolic calcium ion concentration#GO:0051480;ion transmembrane transport#GO:0034220;circulatory system process#GO:0003013;striated muscle contraction#GO:0006941;cellular ion homeostasis#GO:0006873;calcium ion transport into cytosol#GO:0060402;regulation of ion transmembrane transport#GO:0034765;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;calcium ion transmembrane import into cytosol#GO:0097553;regulation of ion transport#GO:0043269;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065;blood circulation#GO:0008015;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;transport#GO:0006810;cytosolic calcium ion transport#GO:0060401;regulation of system process#GO:0044057;cation transport#GO:0006812;cellular homeostasis#GO:0019725;sequestering of calcium ion#GO:0051208;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;cardiac muscle contraction#GO:0060048;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;negative regulation of sequestering of calcium ion#GO:0051283;heart process#GO:0003015;muscle system process#GO:0003012;muscle contraction#GO:0006936 membrane-enclosed lumen#GO:0031974;sarcoplasmic reticulum#GO:0016529;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 calcium-binding protein#PC00060 HUMAN|HGNC=28537|UniProtKB=Q8N6L7 Q8N6L7 TMEM252 PTHR35682:SF1 TRANSMEMBRANE PROTEIN 252 TRANSMEMBRANE PROTEIN 252 HUMAN|HGNC=6199|UniProtKB=O75564 O75564 JRK PTHR19303:SF11 TRANSPOSON JERKY PROTEIN HOMOLOG nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 HUMAN|HGNC=7095|UniProtKB=O15344 O15344 MID1 PTHR24099:SF23 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE MIDLINE-1 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=34352|UniProtKB=Q0P641 Q0P641 C2orf80 PTHR36296:SF1 GAMMA-CRYSTALLIN A GAMMA-CRYSTALLIN C HUMAN|HGNC=5286|UniProtKB=P08908 P08908 HTR1A PTHR24247:SF20 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1A cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;5HT1 type receptor mediated signaling pathway#P04373>5HT1 Receptor#P04404 HUMAN|HGNC=2559|UniProtKB=P78310 P78310 CXADR PTHR44468:SF3 COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR-RELATED COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR HUMAN|HGNC=17060|UniProtKB=Q92845 Q92845 KIFAP3 PTHR15605:SF2 KINESIN-ASSOCIATED PROTEINS KINESIN-ASSOCIATED PROTEIN 3 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cell projection organization#GO:0030030;microtubule-based process#GO:0007017;organelle organization#GO:0006996;movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 HUMAN|HGNC=13604|UniProtKB=Q9UJT9 Q9UJT9 FBXL7 PTHR13318:SF50 UNCHARACTERIZED F-BOX/LRR-REPEAT PROTEIN 7 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=704|UniProtKB=O15143 O15143 ARPC1B PTHR10709:SF10 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1B cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Huntington disease#P00029>Arp2/3 complex#P00811 HUMAN|HGNC=25276|UniProtKB=Q9H0K6 Q9H0K6 PUS7L PTHR13326:SF21 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE 7 HOMOLOG-LIKE PROTEIN isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=11948|UniProtKB=P13805 P13805 TNNT1 PTHR11521:SF6 TROPONIN T TROPONIN T, SLOW SKELETAL MUSCLE cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;muscle cell differentiation#GO:0042692;system process#GO:0003008;developmental process#GO:0032502;myofibril assembly#GO:0030239;muscle structure development#GO:0061061;striated muscle cell differentiation#GO:0051146;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;skeletal muscle contraction#GO:0003009;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;cytoskeleton organization#GO:0007010;sarcomere organization#GO:0045214;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle contraction#GO:0006941;cellular component morphogenesis#GO:0032989;organelle assembly#GO:0070925;cell development#GO:0048468;muscle cell development#GO:0055001;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 actin binding motor protein#PC00040 HUMAN|HGNC=28905|UniProtKB=Q86U90 Q86U90 YRDC PTHR17490:SF10 SUA5 YRDC DOMAIN-CONTAINING PROTEIN, MITOCHONDRIAL tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363 biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=22983|UniProtKB=Q86YI8 Q86YI8 PHF13 PTHR14571:SF13 UNCHARACTERIZED PHD FINGER PROTEIN 13 binding#GO:0005488;chromatin binding#GO:0003682 nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic chromosome condensation#GO:0007076;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 HUMAN|HGNC=14526|UniProtKB=Q9Y3Q0 Q9Y3Q0 NAALAD2 PTHR10404:SF38 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE 2 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153 HUMAN|HGNC=19974|UniProtKB=Q8IUC4 Q8IUC4 RHPN2 PTHR23031:SF5 RHOPHILIN RHOPHILIN-2-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=28677|UniProtKB=Q53SZ7 Q53SZ7 PRR30 PTHR22235:SF2 PROLINE-RICH PROTEIN 30 PROLINE-RICH PROTEIN 30 HUMAN|HGNC=17167|UniProtKB=Q9BQS2 Q9BQS2 SYT15 PTHR10024:SF234 SYNAPTOTAGMIN SYNAPTOTAGMIN-15 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cation transport#GO:0006812;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;vesicle-mediated transport#GO:0016192;response to metal ion#GO:0010038;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;membrane fusion#GO:0061025;exocytosis#GO:0006887;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;export from cell#GO:0140352 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 HUMAN|HGNC=17347|UniProtKB=Q9BUQ8 Q9BUQ8 DDX23 PTHR47958:SF96 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX23-RELATED catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=30045|UniProtKB=Q96Q15 Q96Q15 SMG1 PTHR11139:SF111 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE/THREONINE-PROTEIN KINASE SMG1 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;SAGA-type complex#GO:0070461;peptidase complex#GO:1905368;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;SAGA complex#GO:0000124;membrane-bounded organelle#GO:0043227;DUBm complex#GO:0071819;nuclear lumen#GO:0031981 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=25848|UniProtKB=Q96GQ5 Q96GQ5 RUSF1 PTHR12770:SF31 RUS1 FAMILY PROTEIN C16ORF58 RUS FAMILY MEMBER 1 HUMAN|HGNC=170|UniProtKB=P61158 P61158 ACTR3 PTHR11937:SF175 ACTIN ACTIN-RELATED PROTEIN 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cortical cytoskeleton#GO:0030863;Arp2/3 protein complex#GO:0005885;cortical actin cytoskeleton#GO:0030864;actin cortical patch#GO:0030479;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 HUMAN|HGNC=7511|UniProtKB=Q9H3R2 Q9H3R2 MUC13 PTHR24041:SF30 MUCIN MUCIN-13 cell adhesion molecule#PC00069 HUMAN|HGNC=7109|UniProtKB=Q9UL63 Q9UL63 MKLN1 PTHR15526:SF5 MUSKELIN MUSKELIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=21751|UniProtKB=Q8IY47 Q8IY47 KBTBD2 PTHR24412:SF192 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=27322|UniProtKB=Q86W54 Q86W54 SPATA24 PTHR35155:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 24 SPERMATOGENESIS-ASSOCIATED PROTEIN 24 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=10611|UniProtKB=Q99616 Q99616 CCL13 PTHR12015:SF147 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 13 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=40042|UniProtKB=C9JI98 C9JI98 TMEM238 PTHR28613:SF5 SI:CH211-232M10.4-RELATED TRANSMEMBRANE PROTEIN 238 HUMAN|HGNC=20619|UniProtKB=Q8TDZ2 Q8TDZ2 MICAL1 PTHR24206:SF59 OS06G0237300 PROTEIN [F-ACTIN]-MONOOXYGENASE MICAL1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament bundle organization#GO:0061572 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=6083|UniProtKB=O15503 O15503 INSIG1 PTHR15301:SF11 INSULIN-INDUCED GENE 1 INSULIN-INDUCED GENE 1 PROTEIN positive regulation of gene expression#GO:0010628;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;steroid metabolic process#GO:0008202;cellular response to hormone stimulus#GO:0032870;negative regulation of cell communication#GO:0010648;protein localization to endoplasmic reticulum#GO:0070972;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cell communication#GO:0007154;alcohol metabolic process#GO:0006066;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;maintenance of location#GO:0051235;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;small molecule biosynthetic process#GO:0044283;steroid biosynthetic process#GO:0006694;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;response to peptide hormone#GO:0043434;RNA metabolic process#GO:0016070;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;response to lipid#GO:0033993;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;cellular response to lipid#GO:0071396;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to organic cyclic compound#GO:0071407;protein localization to organelle#GO:0033365;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;organic cyclic compound biosynthetic process#GO:1901362;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;maintenance of location in cell#GO:0051651;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;sterol biosynthetic process#GO:0016126;sterol metabolic process#GO:0016125;cellular localization#GO:0051641;regulation of nitrogen compound metabolic process#GO:0051171;alcohol biosynthetic process#GO:0046165;cholesterol biosynthetic process#GO:0006695;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;cholesterol metabolic process#GO:0008203;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular response to stress#GO:0080135;transcription, DNA-templated#GO:0006351;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;secondary alcohol biosynthetic process#GO:1902653;secondary alcohol metabolic process#GO:1902652;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;RNA biosynthetic process#GO:0032774;response to organonitrogen compound#GO:0010243;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;response to organic cyclic compound#GO:0014070;macromolecule localization#GO:0033036;response to insulin#GO:0032868;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to nitrogen compound#GO:1901699;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular macromolecule biosynthetic process#GO:0034645;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;integral component of membrane#GO:0016021;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;intrinsic component of endoplasmic reticulum membrane#GO:0031227;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=21200|UniProtKB=Q8N9F8 Q8N9F8 ZNF454 PTHR24377:SF864 IP01015P-RELATED ZINC FINGER PROTEIN 454 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=15925|UniProtKB=Q9Y3Z3 Q9Y3Z3 SAMHD1 PTHR11373:SF4 DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;nucleoside triphosphate catabolic process#GO:0009143;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;heterocycle biosynthetic process#GO:0018130;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;purine nucleoside triphosphate metabolic process#GO:0009144;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 hydrolase#PC00121 HUMAN|HGNC=20153|UniProtKB=Q9HCK8 Q9HCK8 CHD8 PTHR45623:SF3 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8 HUMAN|HGNC=43622|UniProtKB=A0A1W2PQJ5 A0A1W2PQJ5 SSU72P3 PTHR20383:SF10 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;RNA processing#GO:0006396;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;mRNA 3'-end processing#GO:0031124;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA 3'-end processing#GO:0031123;mRNA polyadenylation#GO:0006378;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;dephosphorylation#GO:0016311;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 protein phosphatase#PC00195 HUMAN|HGNC=45037|UniProtKB=B5MCY1 B5MCY1 TDRD15 PTHR22948:SF7 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 15 scaffold/adaptor protein#PC00226 HUMAN|HGNC=33816|UniProtKB=Q68D42 Q68D42 TMEM215 PTHR31922:SF2 TRANSMEMBRANE PROTEIN 215 TRANSMEMBRANE PROTEIN 215 HUMAN|HGNC=29395|UniProtKB=Q5VU92 Q5VU92 DCAF12L1 PTHR19860:SF35 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 12-LIKE PROTEIN 1 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 HUMAN|HGNC=8504|UniProtKB=Q969R2 Q969R2 OSBP2 PTHR10972:SF194 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 2 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;cholesterol binding#GO:0015485 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=27071|UniProtKB=A0A087X179 A0A087X179 TBC1D3E PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=7199|UniProtKB=P00540 P00540 MOS PTHR23257:SF706 SERINE-THREONINE PROTEIN KINASE PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE MOS transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;catalytic activity#GO:0003824;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of chromosome segregation#GO:0051983;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;negative regulation of nuclear division#GO:0051784;regulation of intracellular signal transduction#GO:1902531;chromosome segregation#GO:0007059;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;reproductive process#GO:0022414;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;meiotic cell cycle#GO:0051321;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;positive regulation of phosphate metabolic process#GO:0045937;chromosome organization#GO:0051276;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;regulation of chromosome separation#GO:1905818;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;MAPK cascade#GO:0000165;protein modification process#GO:0036211;negative regulation of cell cycle process#GO:0010948;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;meiotic chromosome separation#GO:0051307;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;meiotic cell cycle process#GO:1903046;negative regulation of organelle organization#GO:0010639;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;meiotic chromosome segregation#GO:0045132;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;metaphase/anaphase transition of cell cycle#GO:0044784;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;negative regulation of chromosome separation#GO:1905819;regulation of macromolecule metabolic process#GO:0060255;regulation of meiotic cell cycle#GO:0051445;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;positive regulation of cellular protein metabolic process#GO:0032270 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=28415|UniProtKB=Q5VXH5 Q5VXH5 PRAMEF7 PTHR14224:SF30 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 7-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=742|UniProtKB=P07306 P07306 ASGR1 PTHR22802:SF265 C-TYPE LECTIN SUPERFAMILY MEMBER ASIALOGLYCOPROTEIN RECEPTOR 1 membrane traffic protein#PC00150 HUMAN|HGNC=11530|UniProtKB=P09758 P09758 TACSTD2 PTHR14168:SF5 TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER 2 HUMAN|HGNC=24671|UniProtKB=Q8NFF5 Q8NFF5 FLAD1 PTHR23293:SF9 FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE FAD SYNTHASE adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 transferase#PC00220 Flavin biosynthesis#P02741>FAD synthetase#P02936 HUMAN|HGNC=10461|UniProtKB=P30622 P30622 CLIP1 PTHR18916:SF44 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;microtubule polymerization or depolymerization#GO:0031109;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;cytoplasmic microtubule organization#GO:0031122;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 chaperone#PC00072 HUMAN|HGNC=9969|UniProtKB=P35251 P35251 RFC1 PTHR23389:SF6 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 REPLICATION FACTOR C SUBUNIT 1 DNA metabolism protein#PC00009 DNA replication#P00017>RFC#P00529 HUMAN|HGNC=19431|UniProtKB=O95406 O95406 CNIH1 PTHR12290:SF10 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 1 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 HUMAN|HGNC=16058|UniProtKB=Q9BYT8 Q9BYT8 NLN PTHR11804:SF44 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED NEUROLYSIN, MITOCHONDRIAL hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 metalloprotease#PC00153 HUMAN|HGNC=30953|UniProtKB=Q96DT7 Q96DT7 ZBTB10 PTHR24414:SF27 F-BOX/KELCH-REPEAT PROTEIN SKIP4 ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 10 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=12115|UniProtKB=A0A0A6YYK7 A0A0A6YYK7 TRAV19 PTHR23267:SF450 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 19 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=28311|UniProtKB=Q9BW72 Q9BW72 HIGD2A PTHR12297:SF11 HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED HIG1 DOMAIN FAMILY MEMBER 2A, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=7521|UniProtKB=Q9HBB8 Q9HBB8 CDHR5 PTHR24028:SF243 CADHERIN-87A CADHERIN-RELATED FAMILY MEMBER 5 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 HUMAN|HGNC=26478|UniProtKB=Q5T0U0 Q5T0U0 CCDC122 PTHR12138:SF100 PRIMATE-EXPANDED PROTEIN FAMILY COILED-COIL DOMAIN-CONTAINING PROTEIN 122 HUMAN|HGNC=9651|UniProtKB=Q16825 Q16825 PTPN21 PTHR45706:SF3 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 21 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 protein phosphatase#PC00195 HUMAN|HGNC=26907|UniProtKB=Q8NBW4 Q8NBW4 SLC38A9 PTHR22950:SF244 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 9 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 amino acid transporter#PC00046 HUMAN|HGNC=51337|UniProtKB=A6NJ88 A6NJ88 SAGE2P PTHR12957:SF36 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED SAGE1-LIKE PROTEIN-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 RNA helicase#PC00032 HUMAN|HGNC=8660|UniProtKB=O95206 O95206 PCDH8 PTHR24028:SF46 CADHERIN-87A PROTOCADHERIN-8 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=6162|UniProtKB=P26010 P26010 ITGB7 PTHR10082:SF36 INTEGRIN BETA SUBUNIT INTEGRIN BETA-7 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cell adhesion mediated by integrin#GO:0033627;biological adhesion#GO:0022610;localization of cell#GO:0051674;cell motility#GO:0048870;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;integrin-mediated signaling pathway#GO:0007229;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052 membrane protein complex#GO:0098796;anchoring junction#GO:0070161;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;receptor complex#GO:0043235;cell surface#GO:0009986;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;focal adhesion#GO:0005925;integral component of plasma membrane#GO:0005887;cell-substrate junction#GO:0030055;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Integrin#P00853 HUMAN|HGNC=29305|UniProtKB=Q96CP6 Q96CP6 GRAMD1A PTHR23319:SF8 UNCHARACTERIZED PROTEIN ASTER-A HUMAN|HGNC=31116|UniProtKB=Q5T035 Q5T035 C9orf129 PTHR15976:SF14 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PPAR-GAMMA-LIKE PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=15446|UniProtKB=Q8WWY3 Q8WWY3 PRPF31 PTHR13904:SF0 PRE-MRNA SPLICING FACTOR PRP31 U4/U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=17317|UniProtKB=Q9Y584 Q9Y584 TIMM22 PTHR14110:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 signal sequence binding#GO:0005048;transmembrane transporter activity#GO:0022857;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;amide transmembrane transporter activity#GO:0042887;protein transmembrane transporter activity#GO:0008320;peptide transmembrane transporter activity#GO:1904680;transporter activity#GO:0005215 cellular localization#GO:0051641;protein insertion into mitochondrial inner membrane#GO:0045039;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 transporter#PC00227 HUMAN|HGNC=26498|UniProtKB=Q8N8E2 Q8N8E2 ZNF513 PTHR24403:SF66 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 513 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3012|UniProtKB=Q12882 Q12882 DPYD PTHR43073:SF2 DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] dehydrogenase#PC00092 Pyrimidine Metabolism#P02771>Dihydrouracil Dehydrogenase#P03128 HUMAN|HGNC=14033|UniProtKB=Q96DV4 Q96DV4 MRPL38 PTHR11362:SF133 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 39S RIBOSOMAL PROTEIN L38, MITOCHONDRIAL membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 protease inhibitor#PC00191 EGF receptor signaling pathway#P00018>RKIP#P00548 HUMAN|HGNC=17160|UniProtKB=P53365 P53365 ARFIP2 PTHR12141:SF3 ARFAPTIN-RELATED ARFAPTIN-2 lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;positive regulation of supramolecular fiber organization#GO:1902905;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;peptide transport#GO:0015833;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein transport#GO:0015031;intracellular transport#GO:0046907;macromolecule localization#GO:0033036;positive regulation of organelle organization#GO:0010638;cellular protein localization#GO:0034613;positive regulation of actin filament polymerization#GO:0030838;transport#GO:0006810;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of protein-containing complex assembly#GO:0043254;supramolecular fiber organization#GO:0097435;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;regulation of anatomical structure size#GO:0090066;regulation of actin filament length#GO:0030832;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;positive regulation of protein-containing complex assembly#GO:0031334;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;localization#GO:0051179;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 vesicle coat protein#PC00235 Huntington disease#P00029>Arfaptin-2#P00793 HUMAN|HGNC=13140|UniProtKB=Q9UC06 Q9UC06 ZNF70 PTHR24381:SF82 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 70 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4420|UniProtKB=O43555 O43555 GNRH2 PTHR10522:SF6 GONADOLIBERIN PROGONADOLIBERIN-2 peptide hormone#PC00179 HUMAN|HGNC=44200|UniProtKB=A6NFA1 A6NFA1 TRABD2B PTHR31120:SF8 METALLOPROTEASE TIKI METALLOPROTEASE TIKI2 metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;Wnt-protein binding#GO:0017147;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;Wnt signaling pathway#GO:0016055 intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;intrinsic component of plasma membrane#GO:0031226;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886;integral component of organelle membrane#GO:0031301 metalloprotease#PC00153 HUMAN|HGNC=23149|UniProtKB=Q8NB66 Q8NB66 UNC13C PTHR10480:SF2 PROTEIN UNC-13 HOMOLOG PROTEIN UNC-13 HOMOLOG C syntaxin binding#GO:0019905;protein binding#GO:0005515;calmodulin binding#GO:0005516;SNARE binding#GO:0000149;binding#GO:0005488;syntaxin-1 binding#GO:0017075 vesicle fusion#GO:0006906;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;regulated exocytosis#GO:0045055;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;neuromuscular junction development#GO:0007528;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of neurotransmitter levels#GO:0001505;cell junction organization#GO:0034330;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;synaptic transmission, glutamatergic#GO:0035249;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;terminal bouton#GO:0043195;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;presynaptic membrane#GO:0042734;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;axon terminus#GO:0043679;intracellular#GO:0005622;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;neuromuscular junction#GO:0031594;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell cortex#GO:0005938;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;whole membrane#GO:0098805;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 Synaptic vesicle trafficking#P05734>Munc13#P05773 HUMAN|HGNC=11752|UniProtKB=P19532 P19532 TFE3 PTHR45776:SF3 MIP04163P TRANSCRIPTION FACTOR E3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24553|UniProtKB=Q6IPX3 Q6IPX3 TCEAL6 PTHR14754:SF33 TRANSCRIPTION ELONGATION FACTOR A TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 3-RELATED general transcription factor#PC00259 HUMAN|HGNC=28404|UniProtKB=Q6P3S1 Q6P3S1 DENND1B PTHR13196:SF24 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1B binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;small GTPase binding#GO:0031267;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137;Ras GTPase binding#GO:0017016;Ras guanyl-nucleotide exchange factor activity#GO:0005088;molecular function regulator#GO:0098772;protein binding#GO:0005515;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;Rab guanyl-nucleotide exchange factor activity#GO:0017112 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endocytic recycling#GO:0032456;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=6178|UniProtKB=P23677 P23677 ITPKA PTHR12400:SF55 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE A transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 HUMAN|HGNC=19321|UniProtKB=Q9C056 Q9C056 NKX6-2 PTHR24340:SF21 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-6.2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=33551|UniProtKB=A1L188 A1L188 NDUFAF8 PTHR34561:SF1 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=20338|UniProtKB=Q7L622 Q7L622 G2E3 PTHR12420:SF37 PHD FINGER PROTEIN G2/M PHASE-SPECIFIC E3 UBIQUITIN-PROTEIN LIGASE membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=12434|UniProtKB=P42681 P42681 TXK PTHR24418:SF247 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE TXK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;B cell receptor signaling pathway#GO:0050853;peptidyl-amino acid modification#GO:0018193;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;adaptive immune response#GO:0002250;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;peptidyl-tyrosine modification#GO:0018212;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852 HUMAN|HGNC=9031|UniProtKB=P14555 P14555 PLA2G2A PTHR11716:SF9 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2, MEMBRANE ASSOCIATED cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipase activity#GO:0004620;anion binding#GO:0043168;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;phospholipid metabolic process#GO:0006644;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;phosphorus metabolic process#GO:0006793;leukocyte cell-cell adhesion#GO:0007159;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;T cell proliferation#GO:0042098;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;negative regulation of cell population proliferation#GO:0008285;regulation of cell adhesion#GO:0030155;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;metabolic process#GO:0008152;negative regulation of T cell proliferation#GO:0042130;lymphocyte activation#GO:0046649;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;cellular metabolic process#GO:0044237;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cell adhesion#GO:0007155;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;primary metabolic process#GO:0044238;regulation of T cell proliferation#GO:0042129;negative regulation of cell adhesion#GO:0007162;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;negative regulation of immune system process#GO:0002683;organophosphate metabolic process#GO:0019637;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;cellular lipid metabolic process#GO:0044255 phospholipase#PC00186 HUMAN|HGNC=692|UniProtKB=P40616 P40616 ARL1 PTHR11711:SF415 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 G-protein#PC00020 Integrin signalling pathway#P00034>Arf1#P00923;Huntington disease#P00029>ARF#P00786 HUMAN|HGNC=9563|UniProtKB=Q16401 Q16401 PSMD5 PTHR13554:SF10 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=30813|UniProtKB=Q9NX07 Q9NX07 TRNAU1AP PTHR37457:SF2 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=26808|UniProtKB=Q8N1N2 Q8N1N2 DYNAP PTHR35349:SF7 DYNACTIN-ASSOCIATED PROTEIN DYNACTIN-ASSOCIATED PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 HUMAN|HGNC=11909|UniProtKB=O00300 O00300 TNFRSF11B PTHR23097:SF90 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11B transmembrane signal receptor#PC00197 HUMAN|HGNC=13057|UniProtKB=O43296 O43296 ZNF264 PTHR24377:SF814 IP01015P-RELATED ZINC FINGER PROTEIN 264 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12476|UniProtKB=P61077 P61077 UBE2D3 PTHR24068:SF415 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D3 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=29268|UniProtKB=A5YM72 A5YM72 CARNS1 PTHR48066:SF1 CARNOSINE SYNTHASE 1 CARNOSINE SYNTHASE 1 HUMAN|HGNC=19750|UniProtKB=Q9ULT0 Q9ULT0 TTC7A PTHR23083:SF475 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT PROTEIN 7A protein localization to plasma membrane#GO:0072659;lipid metabolic process#GO:0006629;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;protein localization#GO:0008104;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;localization#GO:0051179;protein localization to cell periphery#GO:1990778;glycerolipid metabolic process#GO:0046486;cellular macromolecule localization#GO:0070727;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=8866|UniProtKB=O60925 O60925 PFDN1 PTHR20903:SF1 PREFOLDIN SUBUNIT 1-RELATED PREFOLDIN SUBUNIT 1 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=25828|UniProtKB=A5PLN9 A5PLN9 TRAPPC13 PTHR13134:SF3 UNCHARACTERIZED TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=18077|UniProtKB=Q9NPE2 Q9NPE2 NGRN PTHR13475:SF3 NEUGRIN NEUGRIN HUMAN|HGNC=24100|UniProtKB=Q6NTF7 Q6NTF7 APOBEC3H PTHR13857:SF43 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3H RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363 response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;RNA phosphodiester bond hydrolysis#GO:0090501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;defense response to virus#GO:0051607;demethylation#GO:0070988;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;transposition#GO:0032196;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;RNA-dependent DNA biosynthetic process#GO:0006278;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;nucleic acid phosphodiester bond hydrolysis#GO:0090305;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147 HUMAN|HGNC=17819|UniProtKB=Q9BXI3 Q9BXI3 NT5C1A PTHR31367:SF2 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;nucleotidase activity#GO:0008252 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=24272|UniProtKB=Q8NBJ9 Q8NBJ9 SIDT2 PTHR12185:SF16 SID1 TRANSMEMBRANE FAMILY MEMEBER SID1 TRANSMEMBRANE FAMILY MEMBER 2 HUMAN|HGNC=28438|UniProtKB=Q8IYN6 Q8IYN6 UBALD2 PTHR31993:SF6 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=6716|UniProtKB=Q9NS15 Q9NS15 LTBP3 PTHR24034:SF46 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 3 extracellular matrix structural protein#PC00103 HUMAN|HGNC=42970|UniProtKB=Q9H9K5 Q9H9K5 ERVMER34-1 PTHR10424:SF8 VIRAL ENVELOPE PROTEIN ENDOGENOUS RETROVIRAL ENVELOPE PROTEIN HEMO viral or transposable element protein#PC00237 HUMAN|Ensembl=ENSG00000285154|UniProtKB=A0A2R8YEH3 A0A2R8YEH3 LOC112268384 PTHR26453:SF115 OLFACTORY RECEPTOR G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=20503|UniProtKB=Q71DI3 Q71DI3 H3C14 PTHR11426:SF232 HISTONE H3 HISTONE H3.2 histone#PC00118 DNA replication#P00017>Histones#P00527 HUMAN|HGNC=4223|UniProtKB=O14793 O14793 MSTN PTHR11848:SF150 TGF-BETA FAMILY GROWTH/DIFFERENTIATION FACTOR 8 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;regulation of signaling#GO:0023051;protein modification process#GO:0036211;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=24736|UniProtKB=P0C875 P0C875 FAM228B PTHR28584:SF3 FAMILY WITH SEQUENCE SIMILARITY 228 MEMBER A PROTEIN FAM228B HUMAN|HGNC=30524|UniProtKB=P0C7W6 P0C7W6 CCDC172 PTHR22419:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 172 COILED-COIL DOMAIN-CONTAINING PROTEIN 172 HUMAN|Ensembl=ENSG00000269466|UniProtKB=P0DPK2 P0DPK2 H3Y1 PTHR11426:SF44 HISTONE H3 HISTONE H3.X-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 histone#PC00118 DNA replication#P00017>Histones#P00527 HUMAN|HGNC=26930|UniProtKB=A0A1W2PR19 A0A1W2PR19 GSTT4 PTHR43917:SF13 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE THETA-4-RELATED transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=24022|UniProtKB=Q9BYD9 Q9BYD9 ACTRT3 PTHR11937:SF159 ACTIN ACTIN-RELATED PROTEIN T3 actin and actin related protein#PC00039 HUMAN|HGNC=33767|UniProtKB=Q6ZNM6 Q6ZNM6 TEX43 PTHR35247:SF1 TESTIS-EXPRESSED PROTEIN 43 TESTIS-EXPRESSED PROTEIN 43 HUMAN|HGNC=9957|UniProtKB=P78509 P78509 RELN PTHR11841:SF1 REELIN REELIN extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=28412|UniProtKB=Q9BQ15 Q9BQ15 NABP2 PTHR13356:SF3 OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED SOSS COMPLEX SUBUNIT B1 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cell cycle checkpoint#GO:0000075;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;recombinational repair#GO:0000725;mitotic nuclear division#GO:0140014;response to abiotic stimulus#GO:0009628;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;response to ionizing radiation#GO:0010212;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;cellular metabolic process#GO:0044237;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;nuclear chromosome, telomeric region#GO:0000784;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;chromosomal region#GO:0098687 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=16909|UniProtKB=O14777 O14777 NDC80 PTHR10643:SF2 KINETOCHORE PROTEIN NDC80 KINETOCHORE PROTEIN NDC80 HOMOLOG nuclear chromosome segregation#GO:0098813;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of chromosome localization#GO:0051303;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;metaphase plate congression#GO:0051310;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic sister chromatid segregation#GO:0000070;mitotic metaphase plate congression#GO:0007080;chromosome localization#GO:0050000;establishment of organelle localization#GO:0051656 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;condensed nuclear chromosome kinetochore#GO:0000778;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 transcription cofactor#PC00217 HUMAN|HGNC=445|UniProtKB=Q7Z333 Q7Z333 SETX PTHR10887:SF495 DNA2/NAM7 HELICASE FAMILY HELICASE SENATAXIN-RELATED HUMAN|HGNC=31810|UniProtKB=A6NGE4 A6NGE4 DCAF8L1 PTHR15574:SF29 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 8-LIKE PROTEIN 1 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=8845|UniProtKB=O15534 O15534 PER1 PTHR11269:SF8 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN HOMOLOG 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;response to radiation#GO:0009314;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;response to light stimulus#GO:0009416;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Circadian clock system#P00015>per#G01503;Circadian clock system#P00015>Per#P00504;Gonadotropin-releasing hormone receptor pathway#P06664>mPer1#G06895;Gonadotropin-releasing hormone receptor pathway#P06664>mPer1#G06681;Circadian clock system#P00015>per#G01499 HUMAN|HGNC=16129|UniProtKB=Q9BYL1 Q9BYL1 SAMD10 PTHR20843:SF1 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 10 HUMAN|HGNC=2378|UniProtKB=O43513 O43513 MED7 PTHR15498:SF72 T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING TIM MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=492|UniProtKB=P16157 P16157 ANK1 PTHR24133:SF38 FAMILY NOT NAMED ANKYRIN-1 ion channel binding#GO:0044325;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=7577|UniProtKB=P12883 P12883 MYH7 PTHR45615:SF1 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-7 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=12215|UniProtKB=A0A577 A0A577 TRBV4-1 PTHR23268:SF109 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 4-1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=12661|UniProtKB=Q9UIW0 Q9UIW0 VAX2 PTHR24339:SF34 HOMEOBOX PROTEIN EMX-RELATED VENTRAL ANTERIOR HOMEOBOX 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=29277|UniProtKB=Q8N1G0 Q8N1G0 ZNF687 PTHR47222:SF2 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 687 HUMAN|HGNC=24517|UniProtKB=Q9Y3T9 Q9Y3T9 NOC2L PTHR12687:SF10 NUCLEOLAR COMPLEX 2 AND RAD4-RELATED NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein binding#GO:0005515;molecular function regulator#GO:0098772;transcription factor binding#GO:0008134;histone binding#GO:0042393;DNA-binding transcription factor binding#GO:0140297 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of chromatin organization#GO:1902275;ribosome biogenesis#GO:0042254;negative regulation of cellular component organization#GO:0051129;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;peptidyl-lysine acetylation#GO:0018394;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of histone modification#GO:0031056;biosynthetic process#GO:0009058;ribosomal large subunit biogenesis#GO:0042273;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;negative regulation of organelle organization#GO:0010639;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 HUMAN|HGNC=6866|UniProtKB=O95819 O95819 MAP4K4 PTHR48015:SF2 SERINE/THREONINE-PROTEIN KINASE TAO MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 4 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861 HUMAN|HGNC=19760|UniProtKB=Q96T51 Q96T51 RUFY1 PTHR45956:SF4 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN AND FYVE DOMAIN-CONTAINING PROTEIN 1 regulation of endocytosis#GO:0030100;macromolecule localization#GO:0033036;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of transport#GO:0051049;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;vesicle organization#GO:0016050 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2440|UniProtKB=P0DML2 P0DML2 CSH1 PTHR11417:SF67 SOMATOTROPIN,PROLACTIN CHORIONIC SOMATOMAMMOTROPIN HORMONE 1-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;response to extracellular stimulus#GO:0009991;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to hormone stimulus#GO:0032870;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of receptor signaling pathway via STAT#GO:1904894;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of growth#GO:0045927;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;tyrosine phosphorylation of STAT protein#GO:0007260;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to peptide hormone#GO:0043434;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;growth#GO:0040007;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of growth#GO:0040008;regulation of receptor signaling pathway via STAT#GO:1904892;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;response to nutrient levels#GO:0031667;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to hormone#GO:0009725;receptor signaling pathway via STAT#GO:0097696;peptidyl-tyrosine modification#GO:0018212;regulation of macromolecule metabolic process#GO:0060255;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 HUMAN|HGNC=12263|UniProtKB=A0JD36 A0JD36 TRDV2 PTHR23267:SF157 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR DELTA VARIABLE 2 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=23028|UniProtKB=Q9H4A9 Q9H4A9 DPEP2 PTHR10443:SF9 MICROSOMAL DIPEPTIDASE DIPEPTIDASE 2 protease#PC00190 HUMAN|HGNC=17720|UniProtKB=Q9BX95 Q9BX95 SGPP1 PTHR14969:SF45 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;lipid modification#GO:0030258;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=9585|UniProtKB=Q13635 Q13635 PTCH1 PTHR46022:SF5 PROTEIN PATCHED PROTEIN PATCHED HOMOLOG 1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Hedgehog signaling pathway#P00025>Patched#P00689 HUMAN|HGNC=1363|UniProtKB=Q9H330 Q9H330 TMEM245 PTHR21716:SF4 TRANSMEMBRANE PROTEIN TRANSMEMBRANE PROTEIN 245 HUMAN|HGNC=8253|UniProtKB=O95918 O95918 OR2H2 PTHR26453:SF617 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2H2 transmembrane signal receptor#PC00197 HUMAN|HGNC=14270|UniProtKB=Q8TAB3 Q8TAB3 PCDH19 PTHR24028:SF40 CADHERIN-87A PROTOCADHERIN-19 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=8816|UniProtKB=O15530 O15530 PDPK1 PTHR24356:SF163 SERINE/THREONINE-PROTEIN KINASE 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PDK1#P00831;Ras Pathway#P04393>PDK#P04555;CCKR signaling map#P06959>PDPK1#P07162;PI3 kinase pathway#P00048>PDK1 ACT#P01190;PI3 kinase pathway#P00048>PDK1#P01196;p53 pathway feedback loops 2#P04398>PDK1/2#P04656;p53 pathway#P00059>PDK1/2#P04616;Interleukin signaling pathway#P00036>PDK1/2#P00985;PDGF signaling pathway#P00047>PDK1/2#P01164;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PDK1/2#P00903;PI3 kinase pathway#P00048>P110ACT#P01177 HUMAN|HGNC=10981|UniProtKB=Q02978 Q02978 SLC25A11 PTHR45618:SF38 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL 2-OXOGLUTARATE/MALATE CARRIER PROTEIN secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;succinate transmembrane transporter activity#GO:0015141;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;dicarboxylic acid transmembrane transporter activity#GO:0005310;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 transmembrane transport#GO:0055085;dicarboxylic acid transport#GO:0006835;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;inorganic anion transmembrane transport#GO:0098661;organic substance transport#GO:0071702;establishment of localization#GO:0051234;anion transport#GO:0006820;C4-dicarboxylate transport#GO:0015740;organic acid transmembrane transport#GO:1903825;inorganic anion transport#GO:0015698 secondary carrier transporter#PC00258 HUMAN|HGNC=2152|UniProtKB=Q8IV77 Q8IV77 CNGA4 PTHR45638:SF2 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL ALPHA-4 cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;inorganic molecular entity transmembrane transporter activity#GO:0015318;nucleotide binding#GO:0000166;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;purine nucleotide binding#GO:0017076;gated channel activity#GO:0022836;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 ligand-gated ion channel#PC00141 HUMAN|HGNC=7326|UniProtKB=P20585 P20585 MSH3 PTHR11361:SF122 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH3 pyrophosphatase activity#GO:0016462;mismatched DNA binding#GO:0030983;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;double-stranded DNA binding#GO:0003690;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;nuclear division#GO:0000280;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;M phase#GO:0000279;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;regulation of hydrolase activity#GO:0051336;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;meiosis I cell cycle phase#GO:0098764;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of hydrolase activity#GO:0051345;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;reproduction#GO:0000003;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of DNA replication#GO:0008156;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;mismatch repair#GO:0006298;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic recombination#GO:0006312;reciprocal meiotic recombination#GO:0007131;regulation of macromolecule biosynthetic process#GO:0010556;cell cycle phase#GO:0022403;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;positive regulation of catalytic activity#GO:0043085;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;homologous recombination#GO:0035825;DNA replication#GO:0006260;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=9040|UniProtKB=Q13093 Q13093 PLA2G7 PTHR10272:SF12 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 protein modifying enzyme#PC00260 HUMAN|HGNC=9501|UniProtKB=Q15438 Q15438 CYTH1 PTHR10663:SF340 GUANYL-NUCLEOTIDE EXCHANGE FACTOR CYTOHESIN-1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=3520|UniProtKB=O00167 O00167 EYA2 PTHR10190:SF7 EYES ABSENT EYES ABSENT HOMOLOG 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 DNA repair#GO:0006281;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of apoptotic signaling pathway#GO:2001233;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;negative regulation of apoptotic signaling pathway#GO:2001234;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;regulation of extrinsic apoptotic signaling pathway#GO:2001236;protein dephosphorylation#GO:0006470;histone modification#GO:0016570;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;response to stress#GO:0006950;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;chromatin organization#GO:0006325;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of DNA repair#GO:0045739;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;protein modification process#GO:0036211;positive regulation of response to DNA damage stimulus#GO:2001022;regulation of DNA repair#GO:0006282;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;negative regulation of programmed cell death#GO:0043069;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cell death#GO:0008219;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of cell death#GO:0010941;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4989|UniProtKB=O00479 O00479 HMGN4 PTHR23087:SF11 NONHISTONE CHROMOSOMAL PROTEIN HMG HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 4 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=30073|UniProtKB=Q14181 Q14181 POLA2 PTHR23061:SF12 DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT DNA POLYMERASE ALPHA SUBUNIT B cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA biosynthetic process#GO:0071897;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704 pre-replicative complex#GO:0036387;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;epsilon DNA polymerase complex#GO:0008622;replisome#GO:0030894;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;replication fork#GO:0005657;membrane-enclosed lumen#GO:0031974;origin recognition complex#GO:0000808;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;DNA replication preinitiation complex#GO:0031261;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;CMG complex#GO:0071162;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 DNA-directed DNA polymerase#PC00018 HUMAN|HGNC=6121|UniProtKB=O14896 O14896 IRF6 PTHR11949:SF9 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=29554|UniProtKB=Q9C0C9 Q9C0C9 UBE2O PTHR46116:SF15 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME HUMAN|HGNC=23169|UniProtKB=Q9Y224 Q9Y224 RTRAF PTHR15924:SF11 CLE RNA TRANSCRIPTION, TRANSLATION AND TRANSPORT FACTOR PROTEIN HUMAN|HGNC=23463|UniProtKB=Q5VTM2 Q5VTM2 AGAP9 PTHR45819:SF7 CENTAURIN-GAMMA-1A ARF-GAP WITH GTPASE, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 4-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=10518|UniProtKB=Q8N1B4 Q8N1B4 VPS52 PTHR14190:SF7 SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;syntaxin binding#GO:0019905;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;SNARE binding#GO:0000149;Rab GTPase binding#GO:0017137 endosomal transport#GO:0016197;cellular localization#GO:0051641;vacuolar transport#GO:0007034;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;Golgi to vacuole transport#GO:0006896;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=23604|UniProtKB=P26371 P26371 KRTAP5-9 PTHR23262:SF131 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-9 HUMAN|HGNC=14809|UniProtKB=Q8NGN3 Q8NGN3 OR10G4 PTHR26453:SF6 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G4-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=4855|UniProtKB=P19113 P19113 HDC PTHR11999:SF68 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE HISTIDINE DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;aromatic amino acid family metabolic process#GO:0009072;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;cellular amino acid metabolic process#GO:0006520;aromatic amino acid family catabolic process#GO:0009074;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 decarboxylase#PC00089 CCKR signaling map#P06959>HDC#G06969;CCKR signaling map#P06959>HDC#G07262;Histamine synthesis#P04387>Histidine decarboxylase#P04493 HUMAN|HGNC=28578|UniProtKB=Q8IV42 Q8IV42 PSTK PTHR20873:SF0 L-SERYL-TRNA(SEC) KINASE L-SERYL-TRNA(SEC) KINASE tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;kinase activity#GO:0016301 HUMAN|HGNC=16347|UniProtKB=Q6IS24 Q6IS24 GALNT17 PTHR11675:SF38 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 17 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=28038|UniProtKB=Q9P0N8 Q9P0N8 MARCHF2 PTHR46065:SF4 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF2 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=26711|UniProtKB=Q9UFG5 Q9UFG5 C19orf25 PTHR34766:SF1 UPF0449 PROTEIN C19ORF25 UPF0449 PROTEIN C19ORF25 HUMAN|HGNC=14952|UniProtKB=Q8TAE6 Q8TAE6 PPP1R14C PTHR16188:SF6 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14C phosphatase binding#GO:0019902;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096;protein phosphatase inhibitor activity#GO:0004864 phosphatase modulator#PC00184 HUMAN|HGNC=13154|UniProtKB=P17098 P17098 ZNF8 PTHR24377:SF622 IP01015P-RELATED ZINC FINGER PROTEIN 8 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28657|UniProtKB=Q9BSW2 Q9BSW2 CRACR2A PTHR22621:SF27 UNCHARACTERIZED EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 4B HUMAN|HGNC=3236|UniProtKB=P00533 P00533 EGFR PTHR24416:SF91 TYROSINE-PROTEIN KINASE RECEPTOR EPIDERMAL GROWTH FACTOR RECEPTOR signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;regulation of molecular function#GO:0065009;epithelial cell proliferation#GO:0050673;apoptotic process#GO:0006915;cell death#GO:0008219;phosphorylation#GO:0016310;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of biological process#GO:0048518;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;cellular developmental process#GO:0048869;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;negative regulation of cell death#GO:0060548;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;basolateral plasma membrane#GO:0016323;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466;Gonadotropin-releasing hormone receptor pathway#P06664>EGFR#P06843 HUMAN|HGNC=15287|UniProtKB=P0C626 P0C626 OR5G3 PTHR26452:SF292 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5G3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=25608|UniProtKB=Q5VIR6 Q5VIR6 VPS53 PTHR12820:SF0 VACUOLAR SORTING PROTEIN 53 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=660|UniProtKB=P36406 P36406 TRIM23 PTHR11711:SF163 ADP RIBOSYLATION FACTOR-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM23 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 HUMAN|HGNC=6323|UniProtKB=Q12840 Q12840 KIF5A PTHR24115:SF937 KINESIN-RELATED KINESIN HEAVY CHAIN ISOFORM 5A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;ATP-dependent microtubule motor activity, plus-end-directed#GO:0008574;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 neuron projection guidance#GO:0097485;microtubule-based protein transport#GO:0099118;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;axonogenesis#GO:0007409;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;protein localization to synapse#GO:0035418;cellular component organization#GO:0016043;peptide transport#GO:0015833;transport along microtubule#GO:0010970;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;taxis#GO:0042330;receptor localization to synapse#GO:0097120;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;developmental process#GO:0032502;transport#GO:0006810;cell projection morphogenesis#GO:0048858;amide transport#GO:0042886;axo-dendritic transport#GO:0008088;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;axon guidance#GO:0007411;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;synaptic vesicle transport#GO:0048489;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cell morphogenesis involved in differentiation#GO:0000904;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;microtubule-based transport#GO:0099111;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;microtubule-based process#GO:0007017;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;generation of neurons#GO:0048699 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=25268|UniProtKB=Q96LR9 Q96LR9 APOLD1 PTHR14096:SF1 APOLIPOPROTEIN L APOLIPOPROTEIN L DOMAIN-CONTAINING PROTEIN 1 lipid binding#GO:0008289;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 apolipoprotein#PC00052 HUMAN|HGNC=27004|UniProtKB=Q5VZ18 Q5VZ18 SHE PTHR15127:SF29 HEAVYWEIGHT, ISOFORM A SH2 DOMAIN-CONTAINING ADAPTER PROTEIN E protein binding#GO:0005515;binding#GO:0005488 HUMAN|HGNC=44356|UniProtKB=A0A1B0GVL6 A0A1B0GVL6 TMEM238L PTHR28613:SF2 SI:CH211-232M10.4-RELATED HCG1800530, ISOFORM CRA_B-RELATED HUMAN|HGNC=32940|UniProtKB=A6NCS4 A6NCS4 NKX2-6 PTHR24340:SF97 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=33869|UniProtKB=Q6ZMN8 Q6ZMN8 CCNI2 PTHR10177:SF57 CYCLINS CYCLIN-I2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 HUMAN|HGNC=25817|UniProtKB=Q5VYS8 Q5VYS8 TUT7 PTHR12271:SF34 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE 7 adenylyltransferase activity#GO:0070566;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;uridylyltransferase activity#GO:0070569;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA 3'-end processing#GO:0031124;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression#GO:0010468;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;gene silencing by miRNA#GO:0035195;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;mRNA polyadenylation#GO:0006378;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;gene silencing by RNA#GO:0031047;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;production of miRNAs involved in gene silencing by miRNA#GO:0035196;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;posttranscriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 HUMAN|HGNC=7208|UniProtKB=O75970 O75970 MPDZ PTHR19964:SF10 MULTIPLE PDZ DOMAIN PROTEIN MULTIPLE PDZ DOMAIN PROTEIN HUMAN|HGNC=12367|UniProtKB=P43897 P43897 TSFM PTHR11741:SF0 ELONGATION FACTOR TS ELONGATION FACTOR TS, MITOCHONDRIAL nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 translation elongation factor#PC00222 HUMAN|HGNC=25235|UniProtKB=Q9UJG1 Q9UJG1 MOSPD1 PTHR34441:SF2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=26221|UniProtKB=Q9H607 Q9H607 OCEL1 PTHR23288:SF15 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL OCCLUDIN/ELL DOMAIN-CONTAINING PROTEIN 1 general transcription factor#PC00259 HUMAN|HGNC=28907|UniProtKB=Q6UXX5 Q6UXX5 ITIH6 PTHR10338:SF155 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H6 protease inhibitor#PC00191 HUMAN|HGNC=7198|UniProtKB=Q86VD1 Q86VD1 MORC1 PTHR23337:SF6 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1 MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=10402|UniProtKB=P39019 P39019 RPS19 PTHR11710:SF25 40S RIBOSOMAL PROTEIN S19 40S RIBOSOMAL PROTEIN S19 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;organelle organization#GO:0006996;ribonucleoprotein complex subunit organization#GO:0071826;ribonucleoprotein complex assembly#GO:0022618;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;ribosome biogenesis#GO:0042254;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=28594|UniProtKB=Q8NEG0 Q8NEG0 FAM71C PTHR22574:SF11 UNCHARACTERIZED PROTEIN FAM71C membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=10916|UniProtKB=Q9BZW2 Q9BZW2 SLC13A1 PTHR10283:SF65 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;inorganic anion transport#GO:0015698;anion transmembrane transport#GO:0098656 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=9026|UniProtKB=Q99569 Q99569 PKP4 PTHR10372:SF8 PLAKOPHILLIN-RELATED PLAKOPHILIN-4 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130 HUMAN|HGNC=8857|UniProtKB=Q9Y5Y5 Q9Y5Y5 PEX16 PTHR13299:SF0 UNCHARACTERIZED PEROXISOMAL MEMBRANE PROTEIN PEX16 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle organization#GO:0006996;peroxisome organization#GO:0007031 peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;microbody membrane#GO:0031903;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 HUMAN|HGNC=13236|UniProtKB=O94763 O94763 URI1 PTHR15111:SF0 RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3 UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;phosphatase inhibitor activity#GO:0019212;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;phosphatase regulator activity#GO:0019208;chromatin binding#GO:0003682;transcription corepressor activity#GO:0003714;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;regulation of phosphatase activity#GO:0010921;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of dephosphorylation#GO:0035305;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of phosphatase activity#GO:0010923;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of dephosphorylation#GO:0035303;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;negative regulation of phosphorus metabolic process#GO:0010563;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of nucleic acid-templated transcription#GO:1903506;negative regulation of catalytic activity#GO:0043086;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of molecular function#GO:0044092 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=17856|UniProtKB=Q9UJ83 Q9UJ83 HACL1 PTHR43710:SF2 2-HYDROXYACYL-COA LYASE 2-HYDROXYACYL-COA LYASE 1 cation binding#GO:0043169;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 lyase#PC00144 HUMAN|HGNC=18035|UniProtKB=O95834 O95834 EML2 PTHR13720:SF50 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule-based process#GO:0007017;organelle organization#GO:0006996 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819 HUMAN|HGNC=7107|UniProtKB=P46013 P46013 MKI67 PTHR21603:SF17 ANTIGEN KI-67-LIKE PROTEIN PROLIFERATION MARKER PROTEIN KI-67 HUMAN|HGNC=17133|UniProtKB=Q13342 Q13342 SP140 PTHR46386:SF8 NUCLEAR BODY PROTEIN SP140 NUCLEAR BODY PROTEIN SP140 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24277|UniProtKB=Q96GY0 Q96GY0 ZC2HC1A PTHR13555:SF25 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1A C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25070|UniProtKB=Q96AP0 Q96AP0 ACD PTHR14487:SF3 ADRENOCORTICAL DYSPLASIA PROTEIN ACD ADRENOCORTICAL DYSPLASIA PROTEIN HOMOLOG telomeric DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 telomere maintenance via telomere lengthening#GO:0010833;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;telomere-telomerase complex assembly#GO:1905324;regulation of biological process#GO:0050789;regulation of telomere maintenance via telomerase#GO:0032210;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;telomere capping#GO:0016233;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;RNA-dependent DNA biosynthetic process#GO:0006278;cellular macromolecule localization#GO:0070727;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;telomere organization#GO:0032200;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;telomere maintenance#GO:0000723;positive regulation of biosynthetic process#GO:0009891;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;protein localization to organelle#GO:0033365;telomere maintenance via telomerase#GO:0007004;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;positive regulation of catalytic activity#GO:0043085;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of telomere maintenance via telomere lengthening#GO:1904356;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of transferase activity#GO:0051338;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;nuclear telomere cap complex#GO:0000783;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781;protein-DNA complex#GO:0032993;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26992|UniProtKB=Q8IVW8 Q8IVW8 SPNS2 PTHR23505:SF4 SPINSTER PROTEIN SPINSTER HOMOLOG 2 transporter#PC00227 HUMAN|HGNC=14210|UniProtKB=Q9UH99 Q9UH99 SUN2 PTHR12911:SF22 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 2 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;nuclear envelope organization#GO:0006998;cellular process#GO:0009987 envelope#GO:0031975;membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=18730|UniProtKB=Q96A08 Q96A08 H2BC1 PTHR23428:SF77 HISTONE H2B HISTONE H2B TYPE 1-A nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=14470|UniProtKB=Q8NG04 Q8NG04 SLC26A10 PTHR11814:SF99 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10 inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;inorganic anion transmembrane transporter activity#GO:0015103;active ion transmembrane transporter activity#GO:0022853 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=1508|UniProtKB=P55210 P55210 CASP7 PTHR10454:SF31 CASPASE CASPASE-7 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 FAS signaling pathway#P00020>Caspase7#P00595;Apoptosis signaling pathway#P00006>Caspase 7#P00300;FAS signaling pathway#P00020>Pro-Caspase7#P00605 HUMAN|HGNC=17868|UniProtKB=Q96PG8 Q96PG8 BBC3 PTHR28639:SF1 BCL-2-BINDING COMPONENT 3 BCL-2-BINDING COMPONENT 3, ISOFORMS 3/4 HUMAN|HGNC=22310|UniProtKB=Q8IV56 Q8IV56 PRR15 PTHR14581:SF4 FAMILY NOT NAMED PROLINE-RICH PROTEIN 15 HUMAN|HGNC=21539|UniProtKB=Q9BX46 Q9BX46 RBM24 PTHR48024:SF10 GEO13361P1-RELATED RNA-BINDING PROTEIN 24 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5824|UniProtKB=A0A087WSY6 A0A087WSY6 IGKV3D-15 PTHR23267:SF331 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=8930|UniProtKB=Q16816 Q16816 PHKG1 PTHR24347:SF386 SERINE/THREONINE-PROTEIN KINASE PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, SKELETAL MUSCLE/HEART ISOFORM non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 HUMAN|HGNC=22953|UniProtKB=Q8TB45 Q8TB45 DEPTOR PTHR22829:SF18 DEP DOMAIN PROTEIN DEP DOMAIN-CONTAINING MTOR-INTERACTING PROTEIN guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=19239|UniProtKB=Q9BT88 Q9BT88 SYT11 PTHR10024:SF115 SYNAPTOTAGMIN SYNAPTOTAGMIN-11 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cation transport#GO:0006812;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;vesicle-mediated transport#GO:0016192;response to metal ion#GO:0010038;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;membrane fusion#GO:0061025;exocytosis#GO:0006887;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;export from cell#GO:0140352 synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cell projection#GO:0042995;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 HUMAN|HGNC=19166|UniProtKB=Q92609 Q92609 TBC1D5 PTHR22957:SF337 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 5 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=2583|UniProtKB=Q14093 Q14093 CYLC2 PTHR16742:SF2 CYCLICIN CYLICIN-2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 structural protein#PC00211 HUMAN|HGNC=33147|UniProtKB=Q9BPZ2 Q9BPZ2 SPIN2B PTHR10405:SF13 SPINDLIN SPINDLIN-2A-RELATED protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18513|UniProtKB=Q9Y6X8 Q9Y6X8 ZHX2 PTHR15467:SF5 ZINC-FINGERS AND HOMEOBOXES RELATED ZINC FINGERS AND HOMEOBOXES PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=29798|UniProtKB=Q5TCX8 Q5TCX8 MAP3K21 PTHR23257:SF750 SERINE-THREONINE PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 21 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=4827|UniProtKB=P68871 P68871 HBB PTHR11442:SF42 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT BETA small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;intracellular#GO:0005622;extracellular region#GO:0005576 HUMAN|HGNC=26118|UniProtKB=Q49MG5 Q49MG5 MAP9 PTHR14739:SF9 MICROTUBULE-ASSOCIATED PROTEIN 9 MICROTUBULE-ASSOCIATED PROTEIN 9 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;cell division#GO:0051301;mitotic spindle organization#GO:0007052;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of cell division#GO:0051302;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;mitotic spindle assembly#GO:0090307;cytoskeleton-dependent cytokinesis#GO:0061640;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;spindle organization#GO:0007051;regulation of cytokinesis#GO:0032465;cytokinesis#GO:0000910;cellular component assembly#GO:0022607;membrane fission#GO:0090148;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;spindle microtubule#GO:0005876;mitotic spindle midzone#GO:1990023;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 HUMAN|HGNC=4746|UniProtKB=P62807 P62807 H2BC4 PTHR23428:SF302 HISTONE H2B HISTONE H2B TYPE 1-C/E/F/G/I nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=24877|UniProtKB=Q969M3 Q969M3 YIPF5 PTHR21236:SF6 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF5 HUMAN|HGNC=16408|UniProtKB=Q8NFV5 Q8NFV5 SPDYE1 PTHR31156:SF26 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E1-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=9623|UniProtKB=P06454 P06454 PTMA PTHR22745:SF0 PROTHYMOSIN ALPHA PROTHYMOSIN ALPHA HUMAN|HGNC=29178|UniProtKB=Q9UPW0 Q9UPW0 FOXJ3 PTHR46078:SF3 FORKHEAD BOX PROTEIN J2 FAMILY MEMBER FORKHEAD BOX PROTEIN J3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16759|UniProtKB=Q6NX49 Q6NX49 ZNF544 PTHR24376:SF213 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 544 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23707|UniProtKB=Q9P255 Q9P255 ZNF492 PTHR24384:SF108 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 492-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=5001|UniProtKB=Q9NP66 Q9NP66 HMG20A PTHR46040:SF1 HIGH MOBILITY GROUP PROTEIN 2 HIGH MOBILITY GROUP PROTEIN 20A regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=28154|UniProtKB=Q9BRJ7 Q9BRJ7 NUDT16L1 PTHR31699:SF6 NUDIX T16 FAMILY MEMBER TUDOR-INTERACTING REPAIR REGULATOR PROTEIN snoRNA binding#GO:0030515;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=29915|UniProtKB=Q5VU65 Q5VU65 NUP210L PTHR23019:SF1 NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210-LIKE envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=20390|UniProtKB=Q9Y6N5 Q9Y6N5 SQOR PTHR10632:SF2 SULFIDE:QUINONE OXIDOREDUCTASE SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL nucleotide binding#GO:0000166;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;metabolic process#GO:0008152 oxidoreductase#PC00176 HUMAN|HGNC=51250|UniProtKB=Q0VF49 Q0VF49 KIAA2012 PTHR21937:SF5 UNCHARACTERIZED GENE 973-RELATED HUMAN|HGNC=11906|UniProtKB=O14798 O14798 TNFRSF10C PTHR46330:SF4 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10C positive regulation of apoptotic process#GO:0043065;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;signaling#GO:0023052;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TRAIL-R#P00276 HUMAN|HGNC=31332|UniProtKB=Q6IQ22 Q6IQ22 RAB12 PTHR47980:SF35 LD44762P RAS-RELATED PROTEIN RAB-12 cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;protein secretion#GO:0009306;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;response to organonitrogen compound#GO:0010243;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;vesicle fusion#GO:0006906;macromolecule localization#GO:0033036;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;cellular protein localization#GO:0034613;transport#GO:0006810;peptide secretion#GO:0002790;cellular response to nitrogen compound#GO:1901699;amide transport#GO:0042886;organic substance transport#GO:0071702;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;regulation of transport#GO:0051049;response to peptide#GO:1901652;cellular response to insulin stimulus#GO:0032869;vesicle organization#GO:0016050;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;response to organic substance#GO:0010033;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;protein localization to membrane#GO:0072657;cellular response to peptide#GO:1901653;Golgi vesicle transport#GO:0048193;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;localization#GO:0051179;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;response to hormone#GO:0009725;membrane fusion#GO:0061025;response to chemical#GO:0042221;organelle organization#GO:0006996;biological regulation#GO:0065007 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;trans-Golgi network transport vesicle#GO:0030140;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=28130|UniProtKB=Q8TB68 Q8TB68 PRR7 PTHR16209:SF3 FAMILY NOT NAMED PROLINE-RICH PROTEIN 7 HUMAN|HGNC=5834|UniProtKB=P06312 P06312 IGKV4-1 PTHR23267:SF425 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 4-1 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=33855|UniProtKB=Q6RFH8 Q6RFH8 DUX4L9 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=26895|UniProtKB=Q3KP31 Q3KP31 ZNF791 PTHR24379:SF106 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 791 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=10682|UniProtKB=Q99643 Q99643 SDHC PTHR10978:SF16 SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respiratory chain complex II#GO:0045273;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092 TCA cycle#P00051>Succinate Dehydrogenase#P01273 HUMAN|HGNC=19253|UniProtKB=O75170 O75170 PPP6R2 PTHR12634:SF15 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 2 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;regulation of phosphoprotein phosphatase activity#GO:0043666;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of phosphatase activity#GO:0010921;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphatase modulator#PC00184 HUMAN|HGNC=32929|UniProtKB=Q6UWQ7 Q6UWQ7 IGFL2 PTHR34827:SF6 INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 3-RELATED INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 2 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=33699|UniProtKB=Q587J8 Q587J8 KHDC3L PTHR19447:SF15 OOCYTE-EXPRESSED PROTEIN HOMOLOG-RELATED KHDC3-LIKE PROTEIN cytoplasm#GO:0005737;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;intracellular#GO:0005622;apical part of cell#GO:0045177 HUMAN|HGNC=11248|UniProtKB=P49223 P49223 SPINT3 PTHR45938:SF6 ACP24A4-RELATED KUNITZ-TYPE PROTEASE INHIBITOR 3-RELATED HUMAN|HGNC=23157|UniProtKB=Q9Y672 Q9Y672 ALG6 PTHR12413:SF1 DOLICHYL GLYCOSYLTRANSFERASE DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;cellular lipid metabolic process#GO:0044255;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111 HUMAN|HGNC=18971|UniProtKB=Q96PC3 Q96PC3 AP1S3 PTHR11753:SF18 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-1 COMPLEX SUBUNIT SIGMA-3 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 HUMAN|HGNC=29349|UniProtKB=Q9C0I3 Q9C0I3 CCSER1 PTHR22461:SF1 UNCHARACTERIZED SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=5713|UniProtKB=P01591 P01591 JCHAIN PTHR10070:SF2 IMMUNOGLOBULIN J CHAIN IMMUNOGLOBULIN J CHAIN immunoglobulin#PC00123 HUMAN|HGNC=30841|UniProtKB=Q7Z3Y8 Q7Z3Y8 KRT27 PTHR23239:SF120 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 27 HUMAN|HGNC=8183|UniProtKB=P34982 P34982 OR1D2 PTHR48001:SF44 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1D2 transmembrane signal receptor#PC00197 HUMAN|HGNC=2602|UniProtKB=Q07973 Q07973 CYP24A1 PTHR24291:SF5 CYTOCHROME P450 FAMILY 4 1,25-DIHYDROXYVITAMIN D(3) 24-HYDROXYLASE, MITOCHONDRIAL oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 response to organic substance#GO:0010033;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid catabolic process#GO:0006706;response to organic cyclic compound#GO:0014070;response to oxygen-containing compound#GO:1901700;cellular metabolic process#GO:0044237;response to lipid#GO:0033993;response to nutrient levels#GO:0031667;lipid catabolic process#GO:0016042;response to extracellular stimulus#GO:0009991;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nutrient#GO:0007584;steroid metabolic process#GO:0008202;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;small molecule catabolic process#GO:0044282;organic cyclic compound metabolic process#GO:1901360;response to chemical#GO:0042221;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281 oxygenase#PC00177 Vitamin D metabolism and pathway#P04396>24-Hydroxylase#G04688;Vitamin D metabolism and pathway#P04396>24-Hydroxylase#P04608 HUMAN|HGNC=16973|UniProtKB=O96001 O96001 PPP1R17 PTHR15387:SF0 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 17 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 17 phosphatase modulator#PC00184 HUMAN|HGNC=16936|UniProtKB=Q86VZ4 Q86VZ4 LRP11 PTHR46876:SF1 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 HUMAN|HGNC=29417|UniProtKB=Q8TF44 Q8TF44 C2CD4C PTHR46291:SF5 C2 DOMAIN-CONTAINING PROTEIN C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4C HUMAN|HGNC=23817|UniProtKB=Q9H9A5 Q9H9A5 CNOT10 PTHR12979:SF5 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cellular protein metabolic process#GO:0032269;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 CCR4-NOT complex#GO:0030014;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=21289|UniProtKB=Q8IWV8 Q8IWV8 UBR2 PTHR21497:SF28 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR2 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;proteolysis#GO:0006508;histone ubiquitination#GO:0016574;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;ubiquitin-dependent protein catabolic process#GO:0006511;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;histone H2A ubiquitination#GO:0033522;negative regulation of biosynthetic process#GO:0009890;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=10961|UniProtKB=Q9NPD5 Q9NPD5 SLCO1B3 PTHR11388:SF89 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B3 secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic hydroxy compound transport#GO:0015850;organic substance transport#GO:0071702;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;lipid transport#GO:0006869 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=1972|UniProtKB=Q8NCG5 Q8NCG5 CHST4 PTHR10704:SF40 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE 4 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=13387|UniProtKB=Q86SG6 Q86SG6 NEK8 PTHR43671:SF44 SERINE/THREONINE-PROTEIN KINASE NEK SERINE/THREONINE-PROTEIN KINASE NEK8 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=23410|UniProtKB=Q969X1 Q969X1 TMBIM1 PTHR23291:SF35 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 3 HUMAN|HGNC=21721|UniProtKB=Q96EH3 Q96EH3 MALSU1 PTHR21043:SF0 IOJAP SUPERFAMILY ORTHOLOG MITOCHONDRIAL ASSEMBLY OF RIBOSOMAL LARGE SUBUNIT PROTEIN 1 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of cellular component biogenesis#GO:0044087;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=19068|UniProtKB=Q8N6F8 Q8N6F8 METTL27 PTHR43591:SF89 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 27 methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824 methyltransferase#PC00155 HUMAN|HGNC=6717|UniProtKB=Q8N2S1 Q8N2S1 LTBP4 PTHR24034:SF43 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 4 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488;cytokine binding#GO:0019955 extracellular matrix structural protein#PC00103 HUMAN|HGNC=43617|UniProtKB=A6NNH2 A6NNH2 FAM90A27P PTHR16035:SF16 PROTEIN FAM90A1 PROTEIN FAM90A1-RELATED HUMAN|Gene=YV023_HUMAN|UniProtKB=A8MUU9 A8MUU9 - PTHR35683:SF7 YALI0C04136P APPLE DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=21445|UniProtKB=Q9BSF8 Q9BSF8 BTBD10 PTHR21637:SF5 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED BTB/POZ DOMAIN-CONTAINING PROTEIN 10 positive regulation of phosphorylation#GO:0042327;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of cellular process#GO:0048522;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of metabolic process#GO:0009893;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=29563|UniProtKB=Q53HC0 Q53HC0 CCDC92 PTHR14882:SF4 COILED-COIL DOMAIN-CONTAINING 74A COILED-COIL DOMAIN-CONTAINING PROTEIN 92 HUMAN|HGNC=10884|UniProtKB=O14893 O14893 GEMIN2 PTHR12794:SF6 GEMIN2 GEM-ASSOCIATED PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=14918|UniProtKB=Q9NYW0 Q9NYW0 TAS2R10 PTHR11394:SF63 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 10 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=28476|UniProtKB=Q9BWQ6 Q9BWQ6 YIPF2 PTHR12822:SF3 UNCHARACTERIZED PROTEIN YIPF2 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=25878|UniProtKB=Q6MZQ0 Q6MZQ0 PRR5L PTHR32428:SF3 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED PROLINE-RICH PROTEIN 5-LIKE regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;TOR signaling#GO:0031929 TORC2 complex#GO:0031932;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=5950|UniProtKB=O75054 O75054 IGSF3 PTHR12207:SF21 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN SUPERFAMILY MEMBER 3 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=162|UniProtKB=Q9Y614 Q9Y614 ACTL7B PTHR11937:SF59 ACTIN ACTIN-LIKE PROTEIN 7B cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 HUMAN|HGNC=7178|UniProtKB=Q13201 Q13201 MMRN1 PTHR15427:SF3 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER MULTIMERIN-1 negative regulation of cellular response to growth factor stimulus#GO:0090288;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;negative regulation of cellular component movement#GO:0051271;tube morphogenesis#GO:0035239;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;vasculature development#GO:0001944;sprouting angiogenesis#GO:0002040;negative regulation of cell motility#GO:2000146;negative regulation of cell communication#GO:0010648;negative regulation of cell migration#GO:0030336;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;tube development#GO:0035295;localization of cell#GO:0051674;cell communication#GO:0007154;endothelial cell migration#GO:0043542;regulation of response to stimulus#GO:0048583;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;locomotion#GO:0040011;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;regulation of anatomical structure morphogenesis#GO:0022603;regulation of signaling#GO:0023051;developmental process#GO:0032502;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;regulation of cell motility#GO:2000145;negative regulation of response to stimulus#GO:0048585;multicellular organism development#GO:0007275;cell motility#GO:0048870;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;localization#GO:0051179;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell migration#GO:0016477 HUMAN|HGNC=677|UniProtKB=P85298 P85298 ARHGAP8 PTHR45808:SF4 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 8 GTPase-activating protein#PC00257 VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520;PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=7127|UniProtKB=P40692 P40692 MLH1 PTHR10073:SF12 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL DNA MISMATCH REPAIR PROTEIN MLH1 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;intracellular#GO:0005622;DNA repair complex#GO:1990391 DNA metabolism protein#PC00009 HUMAN|HGNC=32458|UniProtKB=A6NP11 A6NP11 ZNF716 PTHR24384:SF178 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 716 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=29613|UniProtKB=Q7Z4W2 Q7Z4W2 LYZL2 PTHR11407:SF67 LYSOZYME C LYSOZYME-LIKE PROTEIN 2 HUMAN|HGNC=18370|UniProtKB=Q9H0U4 Q9H0U4 RAB1B PTHR24073:SF1096 DRAB5-RELATED RAS-RELATED PROTEIN RAB-1B GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;process utilizing autophagic mechanism#GO:0061919;organic substance transport#GO:0071702;vacuole organization#GO:0007033;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;autophagosome assembly#GO:0000045;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;autophagosome organization#GO:1905037;intracellular transport#GO:0046907;autophagy#GO:0006914 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=28792|UniProtKB=Q9Y546 Q9Y546 LRRC42 PTHR31994:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 42 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 42 HUMAN|HGNC=882|UniProtKB=Q13535 Q13535 ATR PTHR11139:SF69 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE/THREONINE-PROTEIN KINASE ATR transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;regulation of biological process#GO:0050789;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;DNA damage checkpoint#GO:0000077;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 p53 pathway feedback loops 2#P04398>ATM#P04669;p53 pathway#P00059>ATM/ATR#P01481 HUMAN|HGNC=13583|UniProtKB=Q9UKT5 Q9UKT5 FBXO4 PTHR16008:SF4 F-BOX ONLY PROTEIN 4 F-BOX ONLY PROTEIN 4 HUMAN|HGNC=30546|UniProtKB=Q6P4F2 Q6P4F2 FDX2 PTHR23426:SF64 FERREDOXIN/ADRENODOXIN FERREDOXIN-2, MITOCHONDRIAL oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FDX#P04607 HUMAN|HGNC=28858|UniProtKB=Q9NXG6 Q9NXG6 P4HTM PTHR10869:SF207 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-3-RELATED protein modifying enzyme#PC00260 HUMAN|HGNC=8831|UniProtKB=P01210 P01210 PENK PTHR11438:SF3 PROENKEPHALIN PROENKEPHALIN-A protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;sensory perception#GO:0007600;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;axon terminus#GO:0043679;cell body#GO:0044297;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cell projection#GO:0042995;plasma membrane#GO:0005886 neuropeptide#PC00162 Enkephalin release#P05913>Enkephalin#P05976;Enkephalin release#P05913>preproenkephalin mRNA#G06046;Opioid proenkephalin pathway#P05915>leu-Enkephalin#P05989;Opioid proenkephalin pathway#P05915>peptide F#P05987;Opioid proenkephalin pathway#P05915>Enkephalin#P05991;Opioid proenkephalin pathway#P05915>proenkephalin#P05995;Enkephalin release#P05913>preproenkephalin#G06045;Opioid proenkephalin pathway#P05915>peptide E#P05988;Opioid proenkephalin pathway#P05915>met-Enkephalin#P05992 HUMAN|HGNC=9991|UniProtKB=Q08116 Q08116 RGS1 PTHR10845:SF34 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 1 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 HUMAN|HGNC=2455|UniProtKB=P78368 P78368 CSNK1G2 PTHR11909:SF157 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM GAMMA-2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;macromolecule modification#GO:0043412;membrane organization#GO:0061024;positive regulation of signal transduction#GO:0009967;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of Wnt signaling pathway#GO:0030177;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;vesicle organization#GO:0016050;phosphorylation#GO:0016310;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;localization#GO:0051179;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 HUMAN|HGNC=18711|UniProtKB=Q8N145 Q8N145 LGI3 PTHR24367:SF10 LEUCINE-RICH REPEAT-CONTAINING PROTEIN LEUCINE-RICH REPEAT LGI FAMILY MEMBER 3 HUMAN|HGNC=26853|UniProtKB=Q8N7Z5 Q8N7Z5 ANKRD31 PTHR24176:SF14 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 31-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 31 HUMAN|HGNC=8073|UniProtKB=Q9H4D5 Q9H4D5 NXF3 PTHR10662:SF12 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=25786|UniProtKB=Q9H902 Q9H902 REEP1 PTHR12300:SF33 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;cytoplasmic microtubule#GO:0005881;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;microtubule#GO:0005874;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 HUMAN|HGNC=18870|UniProtKB=Q7Z5Q5 Q7Z5Q5 POLN PTHR10133:SF60 DNA POLYMERASE I DNA POLYMERASE NU hydrolase activity, acting on ester bonds#GO:0016788;DNA-directed DNA polymerase activity#GO:0003887;nuclease activity#GO:0004518;transferase activity#GO:0016740;5'-3' exonuclease activity#GO:0008409;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;DNA polymerase activity#GO:0034061 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;DNA biosynthetic process#GO:0071897;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 DNA-directed DNA polymerase#PC00018 HUMAN|HGNC=37243|UniProtKB=C9JCN9 C9JCN9 HSBP1L1 PTHR19424:SF4 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1-LIKE PROTEIN 1 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12631|UniProtKB=P40818 P40818 USP8 PTHR21646:SF79 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 8 thiol-dependent ubiquitin-specific protease activity#GO:0004843;hydrolase activity#GO:0016787;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein K63-linked deubiquitination#GO:0070536;Ras protein signal transduction#GO:0007265;endomembrane system organization#GO:0010256;protein modification process#GO:0036211;regulation of biological process#GO:0050789;endosome organization#GO:0007032;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;vesicle organization#GO:0016050;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein K48-linked deubiquitination#GO:0071108;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;protein modification by small protein removal#GO:0070646;biological regulation#GO:0065007;protein deubiquitination#GO:0016579 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;endosome#GO:0005768;postsynaptic density#GO:0014069;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cytosol#GO:0005829;extrinsic component of plasma membrane#GO:0019897;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;extrinsic component of membrane#GO:0019898;intracellular#GO:0005622;midbody#GO:0030496;plasma membrane region#GO:0098590;postsynapse#GO:0098794;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;intracellular vesicle#GO:0097708;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 cysteine protease#PC00081 HUMAN|HGNC=21375|UniProtKB=Q5JTD7 Q5JTD7 LRRC73 PTHR25480:SF200 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 73 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 73 HUMAN|HGNC=31295|UniProtKB=A6NJZ3 A6NJZ3 OR6C65 PTHR26454:SF15 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C65 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=34351|UniProtKB=A1L170 A1L170 C1orf226 PTHR11232:SF17 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER CARBOXYL-TERMINAL PDZ LIGAND OF NEURONAL NITRIC OXIDE SYNTHASE PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=17328|UniProtKB=Q96EV8 Q96EV8 DTNBP1 PTHR16294:SF5 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN DYSBINDIN organelle localization#GO:0051640;regulation of protein metabolic process#GO:0051246;organelle membrane fusion#GO:0090174;regulation of localization#GO:0032879;nervous system development#GO:0007399;regulation of biological process#GO:0050789;establishment of vesicle localization#GO:0051650;secretion#GO:0046903;cellular protein metabolic process#GO:0044267;establishment of organelle localization#GO:0051656;neurotransmitter secretion#GO:0007269;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;export from cell#GO:0140352;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;synaptic vesicle transport#GO:0048489;signal release#GO:0023061;neuron differentiation#GO:0030182;vesicle organization#GO:0016050;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;vesicle localization#GO:0051648;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;membrane fusion#GO:0061025;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092;vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;synaptic vesicle cycle#GO:0099504;negative regulation of kinase activity#GO:0033673;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;membrane organization#GO:0061024;microtubule-based movement#GO:0007018;endomembrane system organization#GO:0010256;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter secretion#GO:0046928;plasma membrane bounded cell projection organization#GO:0120036;regulation of vesicle-mediated transport#GO:0060627;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;regulated exocytosis#GO:0045055;negative regulation of protein modification process#GO:0031400;regulation of biological quality#GO:0065008;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;nitrogen compound metabolic process#GO:0006807;regulation of secretion#GO:0051046;regulation of molecular function#GO:0065009;synaptic signaling#GO:0099536;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;trans-synaptic signaling#GO:0099537;negative regulation of protein metabolic process#GO:0051248;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;transport along microtubule#GO:0010970;neuron projection development#GO:0031175;exocytosis#GO:0006887;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;movement of cell or subcellular component#GO:0006928;regulation of trans-synaptic signaling#GO:0099177;neuron development#GO:0048666;intracellular transport#GO:0046907;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;vesicle fusion#GO:0006906;negative regulation of cellular metabolic process#GO:0031324;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;transport#GO:0006810;developmental process#GO:0032502;axo-dendritic transport#GO:0008088;regulation of transport#GO:0051049;neurotransmitter transport#GO:0006836;cytoskeleton-dependent intracellular transport#GO:0030705;phosphorylation#GO:0016310;negative regulation of transferase activity#GO:0051348;synaptic vesicle exocytosis#GO:0016079;metabolic process#GO:0008152;multicellular organism development#GO:0007275;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;cell development#GO:0048468;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;microtubule-based transport#GO:0099111;signal release from synapse#GO:0099643;microtubule-based process#GO:0007017;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;establishment of localization in cell#GO:0051649;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338;organelle transport along microtubule#GO:0072384;vesicle-mediated transport in synapse#GO:0099003;vesicle cytoskeletal trafficking#GO:0099518 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;organelle membrane#GO:0031090;cytosol#GO:0005829;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;BLOC-1 complex#GO:0031083;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=27637|UniProtKB=Q5T8I3 Q5T8I3 FAM102B PTHR21456:SF3 FAMILY WITH SEQUENCE SIMILARITY 102 PROTEIN FAM102B HUMAN|HGNC=23022|UniProtKB=Q86YH2 Q86YH2 ZNF280B PTHR24388:SF56 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 280B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=27568|UniProtKB=Q2M2W7 Q2M2W7 C17orf58 PTHR35967:SF1 UPF0450 PROTEIN C17ORF58 UPF0450 PROTEIN C17ORF58 HUMAN|HGNC=15584|UniProtKB=Q8IYJ3 Q8IYJ3 SYTL1 PTHR45716:SF3 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=29525|UniProtKB=Q8NBF1 Q8NBF1 GLIS1 PTHR45718:SF3 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLIS1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=10894|UniProtKB=O14744 O14744 PRMT5 PTHR10738:SF0 PROTEIN ARGININE N-METHYLTRANSFERASE 5 PROTEIN ARGININE N-METHYLTRANSFERASE 5 N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;histone methylation#GO:0016571;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein alkylation#GO:0008213;protein methylation#GO:0006479;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;peptidyl-arginine methylation#GO:0018216;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 HUMAN|HGNC=12939|UniProtKB=Q13106 Q13106 ZNF154 PTHR24377:SF934 IP01015P-RELATED ZINC FINGER PROTEIN 154 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16645|UniProtKB=Q13595 Q13595 TRA2A PTHR48034:SF14 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 PROTEIN HOMOLOG ALPHA positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;positive regulation of RNA metabolic process#GO:0051254;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=17330|UniProtKB=Q9NUL7 Q9NUL7 DDX28 PTHR24031:SF421 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX28-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28911|UniProtKB=O60831 O60831 PRAF2 PTHR12859:SF1 PRA1 PROTEIN PRA1 FAMILY PROTEIN 2 cellular anatomical entity#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046 HUMAN|HGNC=27709|UniProtKB=A2RUB6 A2RUB6 CCDC66 PTHR22736:SF2 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 66 HUMAN|HGNC=944|UniProtKB=O60241 O60241 ADGRB2 PTHR12011:SF41 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR B2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;regulation of signaling#GO:0023051;peripheral nervous system development#GO:0007422;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 p53 pathway#P00059>BAI-1#G04699 HUMAN|HGNC=23399|UniProtKB=Q5H8C1 Q5H8C1 FREM1 PTHR45739:SF7 MATRIX PROTEIN, PUTATIVE-RELATED FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1 HUMAN|HGNC=18065|UniProtKB=Q9NSY2 Q9NSY2 STARD5 PTHR46374:SF3 PROTEIN CBG07384 STAR-RELATED LIPID TRANSFER PROTEIN 5 HUMAN|HGNC=16711|UniProtKB=Q9Y2C9 Q9Y2C9 TLR6 PTHR24365:SF422 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 6 signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;protein binding#GO:0005515;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;pattern recognition receptor signaling pathway#GO:0002221;cellular process#GO:0009987;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Toll receptor signaling pathway#P00054>TLR1,2,6#P01380;Toll receptor signaling pathway#P00054>TLR#P01346 HUMAN|HGNC=21767|UniProtKB=P0CG23 P0CG23 ZNF853 PTHR23226:SF192 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 853 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9997|UniProtKB=O15492 O15492 RGS16 PTHR10845:SF187 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 16 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=28697|UniProtKB=Q8N4Q0 Q8N4Q0 ZADH2 PTHR43677:SF3 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 oxidoreductase#PC00176 HUMAN|HGNC=13075|UniProtKB=Q9Y2X9 Q9Y2X9 ZNF281 PTHR24388:SF50 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 281-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=19297|UniProtKB=Q07912 Q07912 TNK2 PTHR24418:SF379 TYROSINE-PROTEIN KINASE ACTIVATED CDC42 KINASE 1 HUMAN|HGNC=5527|UniProtKB=P01860 P01860 IGHG3 PTHR23266:SF342 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 3 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=10072|UniProtKB=Q9UDY6 Q9UDY6 TRIM10 PTHR24103:SF329 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 10 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=27880|UniProtKB=Q6ZTN6 Q6ZTN6 ANKRD13D PTHR12447:SF2 UNCHARACTERIZED WITH ANKYRIN REPEAT DOMAIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13D cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=13902|UniProtKB=O75635 O75635 SERPINB7 PTHR11461:SF56 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B7 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=11092|UniProtKB=P03973 P03973 SLPI PTHR19441:SF44 WHEY ACDIC PROTEIN WAP ANTILEUKOPROTEINASE serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antibacterial humoral response#GO:0019731;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=14998|UniProtKB=Q8NGX0 Q8NGX0 OR11L1 PTHR26452:SF701 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 11L1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=26204|UniProtKB=Q8NBP0 Q8NBP0 TTC13 PTHR44523:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 13 TETRATRICOPEPTIDE REPEAT PROTEIN 13 HUMAN|HGNC=26546|UniProtKB=Q2M243 Q2M243 CCDC27 PTHR18853:SF9 FORKHEAD-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 27 HUMAN|HGNC=33632|UniProtKB=A6NMK7 A6NMK7 CPSF4L PTHR23102:SF19 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-LIKE PROTEIN-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 RNA splicing factor#PC00148 HUMAN|HGNC=20244|UniProtKB=Q8N118 Q8N118 CYP4X1 PTHR24291:SF63 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4X1 oxygenase#PC00177 HUMAN|HGNC=20785|UniProtKB=Q5JR12 Q5JR12 PPM1J PTHR13832:SF305 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1J hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=7515|UniProtKB=P98088 P98088 MUC5AC PTHR11339:SF371 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED MUCIN-5AC extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix protein#PC00102 HUMAN|HGNC=22950|UniProtKB=Q70Z35 Q70Z35 PREX2 PTHR22829:SF1 DEP DOMAIN PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 2 PROTEIN guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=12546|UniProtKB=P54855 P54855 UGT2B15 PTHR48043:SF58 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2B15 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=30583|UniProtKB=Q5VXH4 Q5VXH4 PRAMEF6 PTHR14224:SF100 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 11-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=14729|UniProtKB=O95047 O95047 OR2A4 PTHR26451:SF971 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 2A4-RELATED HUMAN|HGNC=123|UniProtKB=P11117 P11117 ACP2 PTHR11567:SF180 ACID PHOSPHATASE-RELATED LYSOSOMAL ACID PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lysosome organization#GO:0007040;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;dephosphorylation#GO:0016311;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphatase#PC00181 HUMAN|HGNC=24178|UniProtKB=Q8WU03 Q8WU03 GLYATL2 PTHR15298:SF4 L-COA N-ACYLTRANSFERASE-RELATED GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 acyltransferase#PC00042 HUMAN|HGNC=5781|UniProtKB=A0A0C4DH68 A0A0C4DH68 IGKV2-24 PTHR23267:SF379 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-24-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=12000|UniProtKB=Q13625 Q13625 TP53BP2 PTHR24131:SF8 APOPTOSIS-STIMULATING OF P53 PROTEIN APOPTOSIS-STIMULATING OF P53 PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=1735|UniProtKB=Q16543 Q16543 CDC37 PTHR12800:SF3 CDC37-RELATED HSP90 CO-CHAPERONE CDC37 protein binding#GO:0005515;heat shock protein binding#GO:0031072;unfolded protein binding#GO:0051082;binding#GO:0005488;chaperone binding#GO:0051087 biological regulation#GO:0065007;regulation of protein stability#GO:0031647;cellular process#GO:0009987;regulation of biological quality#GO:0065008;protein folding#GO:0006457;protein stabilization#GO:0050821 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=11233|UniProtKB=Q9UBP0 Q9UBP0 SPAST PTHR23074:SF86 AAA DOMAIN-CONTAINING SPASTIN hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=16838|UniProtKB=Q9NW07 Q9NW07 ZNF358 PTHR24390:SF167 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 358 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28337|UniProtKB=Q96LT7 Q96LT7 C9orf72 PTHR31855:SF2 GUANINE NUCLEOTIDE EXCHANGE C9ORF72 GUANINE NUCLEOTIDE EXCHANGE C9ORF72 HUMAN|GeneID=392490|UniProtKB=Q56UQ5 Q56UQ5 - PTHR11991:SF9 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TPT1-LIKE PROTEIN-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=24821|UniProtKB=Q8WZ73 Q8WZ73 RFFL PTHR14879:SF2 CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RIFIFYLIN ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;regulation of apoptotic signaling pathway#GO:2001233;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;plasma membrane bounded cell projection organization#GO:0120036;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of apoptotic signaling pathway#GO:2001234;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;negative regulation of signaling#GO:0023057;negative regulation of endopeptidase activity#GO:0010951;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043154;negative regulation of signal transduction#GO:0009968;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;plasma membrane bounded cell projection assembly#GO:0120031;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;execution phase of apoptosis#GO:0097194;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;negative regulation of response to stimulus#GO:0048585;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cell projection assembly#GO:0030031;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=5880|UniProtKB=P01700 P01700 IGLV1-47 PTHR23267:SF413 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 1-44-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=29370|UniProtKB=Q8IWB1 Q8IWB1 ITPRIP PTHR10656:SF8 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=24739|UniProtKB=Q17RQ9 Q17RQ9 NKPD1 PTHR22674:SF4 NTPASE, KAP FAMILY P-LOOP DOMAIN-CONTAINING 1 NTPASE KAP FAMILY P-LOOP DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=3544|UniProtKB=P08709 P08709 F7 PTHR24278:SF26 COAGULATION FACTOR COAGULATION FACTOR VII extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>FVIIa#P00447;Angiogenesis#P00005>FVIIa#P00201;Blood coagulation#P00011>FVII#P00454 HUMAN|HGNC=20656|UniProtKB=Q8NC54 Q8NC54 KCT2 PTHR16502:SF2 UNCHARACTERIZED KERATINOCYTE-ASSOCIATED TRANSMEMBRANE PROTEIN 2 HUMAN|HGNC=4556|UniProtKB=P36969 P36969 GPX4 PTHR11592:SF126 GLUTATHIONE PEROXIDASE PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180 HUMAN|HGNC=7805|UniProtKB=P25208 P25208 NFYB PTHR11064:SF120 CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=28255|UniProtKB=Q96HM7 Q96HM7 PCED1B PTHR14469:SF1 SARCOMA ANTIGEN NY-SAR-23 PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1B HUMAN|HGNC=15171|UniProtKB=Q8NGM1 Q8NGM1 OR4C15 PTHR48002:SF53 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C15 transmembrane signal receptor#PC00197 HUMAN|HGNC=16987|UniProtKB=Q9Y2Z0 Q9Y2Z0 SUGT1 PTHR45862:SF1 PROTEIN SGT1 HOMOLOG PROTEIN SGT1 HOMOLOG biological regulation#GO:0065007;regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821 HUMAN|HGNC=4559|UniProtKB=Q96SL4 Q96SL4 GPX7 PTHR11592:SF5 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 7 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180 HUMAN|HGNC=9768|UniProtKB=P51157 P51157 RAB28 PTHR24073:SF572 DRAB5-RELATED RAS-RELATED PROTEIN RAB-28 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=290|UniProtKB=P35626 P35626 GRK3 PTHR24355:SF17 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE BETA-ADRENERGIC RECEPTOR KINASE 2 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK3#P05941;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Parkinson disease#P00049>GRK#P01234 HUMAN|HGNC=24694|UniProtKB=Q7RTP6 Q7RTP6 MICAL3 PTHR23167:SF51 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED [F-ACTIN]-MONOOXYGENASE MICAL3 HUMAN|HGNC=4244|UniProtKB=O00451 O00451 GFRA2 PTHR10269:SF4 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=10623|UniProtKB=O00175 O00175 CCL24 PTHR12015:SF100 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 24 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=21354|UniProtKB=Q86XR7 Q86XR7 TICAM2 PTHR22811:SF117 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TIR DOMAIN-CONTAINING ADAPTER MOLECULE 2-RELATED endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 Toll receptor signaling pathway#P00054>TRIF#P01344 HUMAN|HGNC=37215|UniProtKB=A6NIK2 A6NIK2 LRRC10B PTHR16083:SF6 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 10B HUMAN|HGNC=13523|UniProtKB=Q9H2X3 Q9H2X3 CLEC4M PTHR22802:SF438 C-TYPE LECTIN SUPERFAMILY MEMBER C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER M membrane traffic protein#PC00150 HUMAN|HGNC=15280|UniProtKB=Q8NGL4 Q8NGL4 OR5D13 PTHR48018:SF33 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5D13 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=11559|UniProtKB=P37837 P37837 TALDO1 PTHR10683:SF18 TRANSALDOLASE TRANSALDOLASE aldolase#PC00044 Pentose phosphate pathway#P02762>Transaldolase#P03081 HUMAN|HGNC=806|UniProtKB=P54709 P54709 ATP1B3 PTHR11523:SF47 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;enzyme activator activity#GO:0008047;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;ATPase activator activity#GO:0001671;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;potassium ion transport#GO:0006813;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;metal ion transport#GO:0030001;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725;export from cell#GO:0140352 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=695|UniProtKB=P40617 P40617 ARL4A PTHR11711:SF139 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4A carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 HUMAN|HGNC=174|UniProtKB=Q13705 Q13705 ACVR2B PTHR23255:SF70 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-2B signaling receptor activity#GO:0038023;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;activin binding#GO:0048185;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007 membrane protein complex#GO:0098796;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;Gonadotropin-releasing hormone receptor pathway#P06664>ActRII/IIB#P06780 HUMAN|HGNC=1286|UniProtKB=Q9NYP9 Q9NYP9 MIS18A PTHR16431:SF2 NEUROGENIC PROTEIN MASTERMIND PROTEIN MIS18-ALPHA protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cellular protein-containing complex assembly#GO:0034622;chromatin assembly or disassembly#GO:0006333;histone exchange#GO:0043486;nucleosome organization#GO:0034728;macromolecule localization#GO:0033036;nucleosome assembly#GO:0006334;cellular protein localization#GO:0034613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;chromosome segregation#GO:0007059;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;chromosome organization#GO:0051276;ATP-dependent chromatin remodeling#GO:0043044;chromatin organization#GO:0006325;protein localization to organelle#GO:0033365;chromatin remodeling#GO:0006338;protein-containing complex subunit organization#GO:0043933;DNA replication-independent nucleosome organization#GO:0034724 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;chromosome#GO:0005694;intracellular#GO:0005622;chromosome, centromeric region#GO:0000775;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=23187|UniProtKB=Q8WY91 Q8WY91 THAP4 PTHR15854:SF4 THAP4 PROTEIN PEROXYNITRITE ISOMERASE THAP4 HUMAN|HGNC=29594|UniProtKB=O14949 O14949 UQCRQ PTHR12119:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C CYTOCHROME B-C1 COMPLEX SUBUNIT 8 electron transfer activity#GO:0009055;oxidoreductase activity#GO:0016491;ubiquinol-cytochrome-c reductase activity#GO:0008121;catalytic activity#GO:0003824;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respiratory chain complex III#GO:0005750;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 HUMAN|HGNC=30005|UniProtKB=U3KPV4 U3KPV4 A3GALT2 PTHR10462:SF33 GLYCOSYLTRANSFERASE-RELATED ALPHA-1,3-GALACTOSYLTRANSFERASE 2 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=24531|UniProtKB=P60006 P60006 ANAPC15 PTHR22526:SF4 UNCHARACTERIZED ANAPHASE-PROMOTING COMPLEX SUBUNIT 15 negative regulation of sister chromatid segregation#GO:0033046;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of mitotic sister chromatid segregation#GO:0033047;negative regulation of cellular component organization#GO:0051129;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;mitotic cell cycle phase transition#GO:0044772;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;negative regulation of organelle organization#GO:0010639;mitotic spindle assembly checkpoint#GO:0007094;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;mitotic cell cycle checkpoint#GO:0007093;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;metaphase/anaphase transition of cell cycle#GO:0044784;negative regulation of chromosome separation#GO:1905819;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;cell cycle#GO:0007049;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 HUMAN|HGNC=20725|UniProtKB=Q9BUY5 Q9BUY5 ZNF426 PTHR24377:SF799 IP01015P-RELATED ZINC FINGER PROTEIN 426 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=15846|UniProtKB=Q9NP74 Q9NP74 PALMD PTHR46881:SF1 PALMDELPHIN PALMDELPHIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=1856|UniProtKB=Q02224 Q02224 CENPE PTHR47968:SF36 CENTROMERE PROTEIN E CENTROMERE-ASSOCIATED PROTEIN E HUMAN|HGNC=20325|UniProtKB=Q9Y5T4 Q9Y5T4 DNAJC15 PTHR12763:SF7 UNCHARACTERIZED DNAJ HOMOLOG SUBFAMILY C MEMBER 15 pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;ATPase activator activity#GO:0001671;enzyme regulator activity#GO:0030234;ATPase activity#GO:0016887 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=12925|UniProtKB=P52738 P52738 ZNF140 PTHR24377:SF36 IP01015P-RELATED ZINC FINGER PROTEIN 140 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=29198|UniProtKB=Q96AT1 Q96AT1 KIAA1143 PTHR31195:SF2 UNCHARACTERIZED DUF4604 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=20229|UniProtKB=Q8WV16 Q8WV16 DCAF4 PTHR44472:SF3 DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 4 HUMAN|HGNC=10330|UniProtKB=P46779 P46779 RPL28 PTHR10544:SF12 60S RIBOSOMAL PROTEIN L28 60S RIBOSOMAL PROTEIN L28 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=16372|UniProtKB=Q9UBU6 Q9UBU6 FAM8A1 PTHR13659:SF5 AUTOSOMAL HIGHLY CONSERVED PROTEIN PROTEIN FAM8A1 HUMAN|HGNC=10497|UniProtKB=P31151 P31151 S100A7 PTHR11639:SF128 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A7 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 calmodulin-related#PC00061 HUMAN|HGNC=21018|UniProtKB=P59923 P59923 ZNF445 PTHR24376:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 445 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=10971|UniProtKB=Q9Y694 Q9Y694 SLC22A7 PTHR24064:SF33 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 7 secondary carrier transporter#PC00258 HUMAN|HGNC=15362|UniProtKB=Q8NGC0 Q8NGC0 OR5AU1 PTHR26452:SF186 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AU1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=16959|UniProtKB=O15498 O15498 YKT6 PTHR45806:SF1 SYNAPTOBREVIN HOMOLOG YKT6 SYNAPTOBREVIN HOMOLOG YKT6 HUMAN|HGNC=19008|UniProtKB=Q9NVR0 Q9NVR0 KLHL11 PTHR24412:SF420 KELCH PROTEIN KELCH-LIKE PROTEIN 11 scaffold/adaptor protein#PC00226 HUMAN|HGNC=31804|UniProtKB=Q7Z2X7 Q7Z2X7 PAGE2 PTHR14047:SF34 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN FAMILY E MEMBER 3-RELATED HUMAN|HGNC=8216|UniProtKB=Q8NGR5 Q8NGR5 OR1L4 PTHR48001:SF84 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1L4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=6908|UniProtKB=O00339 O00339 MATN2 PTHR24020:SF35 COLLAGEN ALPHA MATRILIN-2 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=6365|UniProtKB=Q9Y5K2 Q9Y5K2 KLK4 PTHR24271:SF65 KALLIKREIN-RELATED KALLIKREIN-4 odontogenesis of dentin-containing tooth#GO:0042475;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;anatomical structure formation involved in morphogenesis#GO:0048646;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;cellular component disassembly#GO:0022411;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=2500|UniProtKB=P29279 P29279 CCN2 PTHR11348:SF7 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN FAMILY MEMBER 2 carbohydrate derivative binding#GO:0097367;integrin binding#GO:0005178;binding#GO:0005488;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;biological adhesion#GO:0022610;cell adhesion#GO:0007155;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;regulation of cell death#GO:0010941;cell death#GO:0008219;biological regulation#GO:0065007;signaling#GO:0023052;negative regulation of cellular process#GO:0048523 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=18105|UniProtKB=Q8N687 Q8N687 DEFB125 PTHR15001:SF12 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 125 antimicrobial response protein#PC00051 HUMAN|HGNC=12695|UniProtKB=P41587 P41587 VIPR2 PTHR45620:SF22 PDF RECEPTOR-LIKE PROTEIN-RELATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=841|UniProtKB=P05496 P05496 ATP5MC1 PTHR10031:SF32 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, MITOCHONDRIAL cation channel activity#GO:0005261;ligase activity#GO:0016874;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide biosynthetic process#GO:0009152 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 HUMAN|HGNC=24263|UniProtKB=Q9Y3E2 Q9Y3E2 BOLA1 PTHR46229:SF2 BOLA TRANSCRIPTION REGULATOR BOLA-LIKE PROTEIN 1 HUMAN|HGNC=30204|UniProtKB=Q9H0W9 Q9H0W9 C11orf54 PTHR13204:SF1 PTD012 PROTEIN ESTER HYDROLASE C11ORF54 cation binding#GO:0043169;hydrolase activity, acting on ester bonds#GO:0016788;binding#GO:0005488;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;ion binding#GO:0043167 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=6995|UniProtKB=Q02080 Q02080 MEF2B PTHR11945:SF383 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;histone deacetylase binding#GO:0042826;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;CCKR signaling map#P06959>MEF2B#P07075;Oxidative stress response#P00046>MEF-2#P01128 HUMAN|HGNC=18042|UniProtKB=Q96LI5 Q96LI5 CNOT6L PTHR12121:SF35 CARBON CATABOLITE REPRESSOR PROTEIN 4 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=26821|UniProtKB=Q6ZP82 Q6ZP82 CCDC141 PTHR12231:SF260 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 141 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=22931|UniProtKB=Q9P2N7 Q9P2N7 KLHL13 PTHR45632:SF7 LD33804P KELCH-LIKE PROTEIN 13 cellular anatomical entity#GO:0110165;midbody#GO:0030496 HUMAN|Ensembl=ENSG00000268041|UniProtKB=A0A1W2PQ73 A0A1W2PQ73 ERFL PTHR11849:SF165 ETS ETS DOMAIN-CONTAINING TRANSCRIPTION FACTOR ERF-LIKE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=5669|UniProtKB=A0A0B4J1V7 A0A0B4J1V7 IGHV7-81 PTHR23266:SF286 IMMUNOGLOBULIN HEAVY CHAIN NON-FUNCTIONAL IMMUNOGLOBULIN HEAVY VARIABLE 7-81-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=23038|UniProtKB=Q9NUN5 Q9NUN5 LMBRD1 PTHR16130:SF2 LYSOSOMAL COBALAMIN TRANSPORTER-RELATED LYSOSOMAL COBALAMIN TRANSPORT ESCORT PROTEIN LMBD1 transporter#PC00227 HUMAN|HGNC=8791|UniProtKB=Q13946 Q13946 PDE7A PTHR11347:SF96 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 7A hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 phosphodiesterase#PC00185 HUMAN|HGNC=12225|UniProtKB=A0A5A2 A0A5A2 TRBV5-8 PTHR23268:SF113 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 5-8 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=9990|UniProtKB=P47804 P47804 RGR PTHR24240:SF90 OPSIN RPE-RETINAL G PROTEIN-COUPLED RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to abiotic stimulus#GO:0071214;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=29252|UniProtKB=Q9P2K6 Q9P2K6 KLHL42 PTHR45972:SF2 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH-LIKE PROTEIN 42 HUMAN|HGNC=17710|UniProtKB=Q9Y3P8 Q9Y3P8 SIT1 PTHR15604:SF0 SIGNALING THRESHOLD-REGULATING TRANSMEMBRANE ADAPTER 1 SIGNALING THRESHOLD-REGULATING TRANSMEMBRANE ADAPTER 1 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900 cell activation#GO:0001775;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;T cell activation#GO:0042110;lymphocyte activation#GO:0046649;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;cellular process#GO:0009987;regulation of T cell activation#GO:0050863;leukocyte activation#GO:0045321;regulation of lymphocyte activation#GO:0051249 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=24275|UniProtKB=Q8NBX0 Q8NBX0 SCCPDH PTHR12286:SF5 UNCHARACTERIZED SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycolipid biosynthetic process#GO:0009247;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=2301|UniProtKB=O75976 O75976 CPD PTHR11532:SF73 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease#PC00190 HUMAN|HGNC=30222|UniProtKB=O95397 O95397 PLEKHA8P1 PTHR10219:SF75 GLYCOLIPID TRANSFER PROTEIN-RELATED PROTEIN PLEKHA9-RELATED binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 transfer/carrier protein#PC00219 HUMAN|HGNC=18010|UniProtKB=Q9NXN4 Q9NXN4 GDAP2 PTHR11106:SF72 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2 HUMAN|HGNC=29246|UniProtKB=Q9P2M4 Q9P2M4 TBC1D14 PTHR22957:SF367 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 14 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;nucleoside-triphosphatase activity#GO:0017111 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of autophagosome assembly#GO:2000785;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;amide transport#GO:0042886;organic substance transport#GO:0071702;vacuole organization#GO:0007033;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;catabolic process#GO:0009056;regulation of hydrolase activity#GO:0051336;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;macromolecule metabolic process#GO:0043170;regulation of GTPase activity#GO:0043087;regulation of organelle organization#GO:0033043;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of macroautophagy#GO:0016241;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;peptide transport#GO:0015833;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;autophagosome#GO:0005776;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 HUMAN|HGNC=16955|UniProtKB=Q99501 Q99501 GAS2L1 PTHR46756:SF16 TRANSGELIN GAS2-LIKE PROTEIN 1 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;tubulin binding#GO:0015631;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;protein binding#GO:0005515;microtubule binding#GO:0008017;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 HUMAN|HGNC=14177|UniProtKB=Q6PII5 Q6PII5 HAGHL PTHR11935:SF77 BETA LACTAMASE DOMAIN HYDROXYACYLGLUTATHIONE HYDROLASE-LIKE PROTEIN HUMAN|HGNC=17495|UniProtKB=Q8NFK1 Q8NFK1 GJC3 PTHR11984:SF56 CONNEXIN GAP JUNCTION GAMMA-3 PROTEIN gap junction#PC00105 HUMAN|HGNC=4503|UniProtKB=Q9Y5Y3 Q9Y5Y3 GPR45 PTHR24245:SF4 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 45-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 HUMAN|HGNC=26861|UniProtKB=Q8N5S3 Q8N5S3 C2orf73 PTHR35087:SF1 SIMILAR TO HYPOTHETICAL PROTEIN FLJ40298 SIMILAR TO HYPOTHETICAL PROTEIN FLJ40298 HUMAN|HGNC=33429|UniProtKB=Q58G82 Q58G82 SYT14P1 PTHR46129:SF3 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN-14-RELATED HUMAN|HGNC=17327|UniProtKB=Q9BTA9 Q9BTA9 WAC PTHR15911:SF6 WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL scaffold/adaptor protein#PC00226 HUMAN|HGNC=3826|UniProtKB=P21462 P21462 FPR1 PTHR24225:SF15 CHEMOTACTIC RECEPTOR FMET-LEU-PHE RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;complement binding#GO:0001848;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;immune response-regulating signaling pathway#GO:0002764;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;activation of immune response#GO:0002253;divalent inorganic cation homeostasis#GO:0072507;regulation of lipase activity#GO:0060191;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;immune response-activating signal transduction#GO:0002757;activation of phospholipase C activity#GO:0007202;regulation of immune system process#GO:0002682;regulation of hydrolase activity#GO:0051336;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;cellular cation homeostasis#GO:0030003;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;regulation of immune response#GO:0050776;positive regulation of phospholipase activity#GO:0010518;positive regulation of immune system process#GO:0002684;homeostatic process#GO:0042592;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;metal ion homeostasis#GO:0055065 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=12558|UniProtKB=O75385 O75385 ULK1 PTHR24348:SF19 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE/THREONINE-PROTEIN KINASE ULK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;growth#GO:0040007;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;axon extension#GO:0048675;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular protein metabolic process#GO:0044267;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;developmental cell growth#GO:0048588;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;cell morphogenesis involved in differentiation#GO:0000904;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cell growth#GO:0016049;cellular component morphogenesis#GO:0032989;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure development#GO:0048856;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=29669|UniProtKB=Q96FT9 Q96FT9 IFT43 PTHR33724:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG HUMAN|HGNC=9975|UniProtKB=P14373 P14373 TRIM27 PTHR24103:SF362 E3 UBIQUITIN-PROTEIN LIGASE TRIM ZINC FINGER PROTEIN RFP ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;protein polyubiquitination#GO:0000209;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;protein K63-linked ubiquitination#GO:0070534 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=28052|UniProtKB=Q9NQH7 Q9NQH7 XPNPEP3 PTHR43226:SF4 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO AMINOPEPTIDASE 3 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153 HUMAN|HGNC=27806|UniProtKB=Q5GH73 Q5GH73 XKR6 PTHR16024:SF9 XK-RELATED PROTEIN XK-RELATED PROTEIN 6 cellular component biogenesis#GO:0044085;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;developmental process#GO:0032502;endomembrane system organization#GO:0010256;plasma membrane bounded cell projection organization#GO:0120036;lipid transport#GO:0006869;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anion transport#GO:0006820;apoptotic process#GO:0006915;lipid translocation#GO:0034204;cell death#GO:0008219;vesicle organization#GO:0016050;lipid localization#GO:0010876;phospholipid translocation#GO:0045332;cellular component assembly#GO:0022607;organophosphate ester transport#GO:0015748;phagocytosis#GO:0006909;organic anion transport#GO:0015711;ion transport#GO:0006811;endocytosis#GO:0006897;plasma membrane phospholipid scrambling#GO:0017121;vesicle-mediated transport#GO:0016192;programmed cell death#GO:0012501;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;phospholipid transport#GO:0015914;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;anatomical structure development#GO:0048856;biological regulation#GO:0065007;plasma membrane bounded cell projection assembly#GO:0120031;apoptotic cell clearance#GO:0043277 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=2771|UniProtKB=P00746 P00746 CFD PTHR24271:SF54 KALLIKREIN-RELATED COMPLEMENT FACTOR D serine protease#PC00203 HUMAN|HGNC=1190|UniProtKB=Q9NZP6 Q9NZP6 NPAP1 PTHR23193:SF15 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE-ASSOCIATED PROTEIN 1 signal sequence binding#GO:0005048;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=28344|UniProtKB=Q8NEQ5 Q8NEQ5 C1orf162 PTHR37997:SF1 TRANSMEMBRANE PROTEIN C1ORF162 TRANSMEMBRANE PROTEIN C1ORF162 HUMAN|HGNC=13564|UniProtKB=Q92563 Q92563 SPOCK2 PTHR13866:SF18 SPARC OSTEONECTIN TESTICAN-2 cation binding#GO:0043169;extracellular matrix binding#GO:0050840;binding#GO:0005488;collagen binding#GO:0005518;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein-containing complex binding#GO:0044877;ion binding#GO:0043167 anatomical structure development#GO:0048856;developmental process#GO:0032502 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=30915|UniProtKB=P61962 P61962 DCAF7 PTHR19919:SF0 WD REPEAT CONTAINING PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 7 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=24305|UniProtKB=Q15021 Q15021 NCAPD2 PTHR14222:SF2 CONDENSIN CONDENSIN COMPLEX SUBUNIT 1 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic chromosome condensation#GO:0007076;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;chromosome organization involved in meiotic cell cycle#GO:0070192;DNA packaging#GO:0006323;mitotic cell cycle#GO:0000278;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;chromosome organization#GO:0051276;meiotic cell cycle process#GO:1903046;reproductive process#GO:0022414;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;chromosomal region#GO:0098687 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=24134|UniProtKB=Q8WYQ9 Q8WYQ9 ZCCHC14 PTHR16195:SF16 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 14 HUMAN|HGNC=29425|UniProtKB=Q8TF20 Q8TF20 ZNF721 PTHR24376:SF210 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 721-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=17441|UniProtKB=Q9UKL0 Q9UKL0 RCOR1 PTHR16089:SF11 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 1 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 HUMAN|HGNC=10417|UniProtKB=P62979 P62979 RPS27A PTHR10666:SF401 UBIQUITIN UBIQUITIN-40S RIBOSOMAL PROTEIN S27A enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4123|UniProtKB=Q10472 Q10472 GALNT1 PTHR11675:SF123 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=14629|UniProtKB=Q53HL2 Q53HL2 CDCA8 PTHR16040:SF6 AUSTRALIN, ISOFORM A-RELATED BOREALIN nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;mitotic sister chromatid segregation#GO:0000070 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;spindle midzone#GO:0051233;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;spindle#GO:0005819 HUMAN|HGNC=11023|UniProtKB=Q9Y2D2 Q9Y2D2 SLC35A3 PTHR10231:SF36 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-N-ACETYLGLUCOSAMINE TRANSPORTER carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;pyrimidine nucleotide-sugar transmembrane transporter activity#GO:0015165;UDP-galactose transmembrane transporter activity#GO:0005459;nucleotide-sugar transmembrane transporter activity#GO:0005338;transporter activity#GO:0005215 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=26349|UniProtKB=Q96LK8 Q96LK8 SPATA32 PTHR37338:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 32 SPERMATOGENESIS-ASSOCIATED PROTEIN 32 HUMAN|HGNC=3036|UniProtKB=Q02487 Q02487 DSC2 PTHR24025:SF0 DESMOGLEIN FAMILY MEMBER DESMOCOLLIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cadherin#PC00057 HUMAN|HGNC=14464|UniProtKB=Q96T55 Q96T55 KCNK16 PTHR11003:SF104 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 16 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=4623|UniProtKB=P00390 P00390 GSR PTHR42737:SF2 GLUTATHIONE REDUCTASE GLUTATHIONE REDUCTASE, MITOCHONDRIAL nucleotide binding#GO:0000166;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;disulfide oxidoreductase activity#GO:0015036;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;sulfur compound metabolic process#GO:0006790;cellular response to chemical stimulus#GO:0070887;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular nitrogen compound metabolic process#GO:0034641;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;cellular modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=26409|UniProtKB=Q96NL1 Q96NL1 TMEM74 PTHR16125:SF3 TRANSMEMBRANE PROTEIN 74 TRANSMEMBRANE PROTEIN 74 HUMAN|HGNC=4108|UniProtKB=O60829 O60829 PAGE4 PTHR14047:SF11 P ANTIGEN FAMILY MEMBER 5-RELATED P ANTIGEN FAMILY MEMBER 4 HUMAN|HGNC=4720|UniProtKB=P22492 P22492 H1-6 PTHR11467:SF18 HISTONE H1 HISTONE H1T nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 positive regulation of gene expression#GO:0010628;male gamete generation#GO:0048232;cellular component biogenesis#GO:0044085;negative regulation of chromosome organization#GO:2001251;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of cellular component organization#GO:0051128;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;gene silencing#GO:0016458;reproductive process#GO:0022414;regulation of chromatin organization#GO:1902275;protein-containing complex subunit organization#GO:0043933;gamete generation#GO:0007276;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular aromatic compound metabolic process#GO:0006725;chromatin assembly or disassembly#GO:0006333;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;chromosome condensation#GO:0030261;chromatin assembly#GO:0031497;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;multi-organism process#GO:0051704;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of DNA recombination#GO:0000018;negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of chromatin silencing#GO:0031935;regulation of RNA biosynthetic process#GO:2001141;negative regulation of chromatin silencing#GO:0031936;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;spermatogenesis#GO:0007283;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;regulation of gene expression, epigenetic#GO:0040029;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;RNA biosynthetic process#GO:0032774;positive regulation of cellular process#GO:0048522;developmental process involved in reproduction#GO:0003006;DNA packaging#GO:0006323;sexual reproduction#GO:0019953;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular biosynthetic process#GO:0031327;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;nucleosome organization#GO:0034728;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;regulation of gene expression#GO:0010468;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;multicellular organism reproduction#GO:0032504;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;negative regulation of gene expression, epigenetic#GO:0045814;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone#PC00118 HUMAN|HGNC=15720|UniProtKB=Q13033 Q13033 STRN3 PTHR15653:SF3 STRIATIN STRIATIN-3 phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein-containing complex binding#GO:0044877;protein phosphatase binding#GO:0019903;binding#GO:0005488 somatodendritic compartment#GO:0036477;neuron projection#GO:0043005;plasma membrane region#GO:0098590;dendrite#GO:0030425;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=490|UniProtKB=Q9UKU9 Q9UKU9 ANGPTL2 PTHR19143:SF24 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 2 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=886|UniProtKB=P46100 P46100 ATRX PTHR46357:SF1 TRANSCRIPTIONAL REGULATOR ATRX TRANSCRIPTIONAL REGULATOR ATRX DNA-binding transcription factor#PC00218 HUMAN|HGNC=14879|UniProtKB=Q9UL03 Q9UL03 INTS6 PTHR12957:SF23 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED INTEGRATOR COMPLEX SUBUNIT 6 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 RNA helicase#PC00032 HUMAN|HGNC=16463|UniProtKB=O75400 O75400 PRPF40A PTHR11864:SF20 PRE-MRNA-PROCESSING PROTEIN PRP40 PRE-MRNA-PROCESSING FACTOR 40 HOMOLOG A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=6281|UniProtKB=Q9Y257 Q9Y257 KCNK6 PTHR11003:SF28 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 6 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=30215|UniProtKB=Q6ZN28 Q6ZN28 MACC1 PTHR15603:SF1 SH3 DOMAIN-CONTAINING PROTEIN METASTASIS-ASSOCIATED IN COLON CANCER PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=29158|UniProtKB=Q9Y2G9 Q9Y2G9 SBNO2 PTHR12706:SF5 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH HOMOLOG 2 nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;histone binding#GO:0042393 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=10489|UniProtKB=P80511 P80511 S100A12 PTHR11639:SF77 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A12 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;endothelial cell migration#GO:0043542;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;humoral immune response#GO:0006959;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;antimicrobial humoral immune response mediated by antimicrobial peptide#GO:0061844;cellular biosynthetic process#GO:0044249;cell motility#GO:0048870;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;antimicrobial humoral response#GO:0019730;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;cell migration#GO:0016477;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 calmodulin-related#PC00061 HUMAN|HGNC=372|UniProtKB=Q9Y2D5 Q9Y2D5 AKAP2 PTHR10498:SF10 PARALEMMIN-RELATED A-KINASE ANCHOR PROTEIN 2-RELATED HUMAN|HGNC=11855|UniProtKB=P19075 P19075 TSPAN8 PTHR19282:SF380 TETRASPANIN TETRASPANIN-8 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=9848|UniProtKB=P49792 P49792 RANBP2 PTHR23138:SF87 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26587|UniProtKB=Q8IV35 Q8IV35 WDR49 PTHR44324:SF1 WD40 REPEAT DOMAIN 95 WD REPEAT-CONTAINING PROTEIN 49 HUMAN|HGNC=17280|UniProtKB=Q9Y2G4 Q9Y2G4 ANKRD6 PTHR24203:SF45 ANKYRIN REPEAT FAMILY PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 6 Wnt signaling pathway#P00057>Diversin#P01466 HUMAN|HGNC=19911|UniProtKB=Q5T6F0 Q5T6F0 DCAF12 PTHR19860:SF10 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 12 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 HUMAN|HGNC=30384|UniProtKB=Q9UMX5 Q9UMX5 NENF PTHR10281:SF92 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED NEUDESIN cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=23237|UniProtKB=Q8WWP7 Q8WWP7 GIMAP1 PTHR10903:SF74 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=9773|UniProtKB=Q14088 Q14088 RAB33A PTHR47978:SF30 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33A endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=23404|UniProtKB=Q9P2V4 Q9P2V4 LRIT1 PTHR45842:SF9 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT, IMMUNOGLOBULIN-LIKE DOMAIN AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=23599|UniProtKB=Q6L8H1 Q6L8H1 KRTAP5-4 PTHR23262:SF226 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-4-RELATED HUMAN|HGNC=19085|UniProtKB=O95476 O95476 CTDNEP1 PTHR12210:SF140 NUCLEAR LIM INTERACTOR-INTERACTING FACTOR-RELATED CTD NUCLEAR ENVELOPE PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 HUMAN|HGNC=20708|UniProtKB=O95704 O95704 APBB3 PTHR14058:SF10 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 3 amyloid-beta binding#GO:0001540;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Alzheimer disease-presenilin pathway#P00004>Fe65#P00126 HUMAN|HGNC=19082|UniProtKB=Q8IZF0 Q8IZF0 NALCN PTHR46141:SF1 SODIUM LEAK CHANNEL NON-SELECTIVE PROTEIN SODIUM LEAK CHANNEL NON-SELECTIVE PROTEIN ion channel#PC00133 HUMAN|HGNC=24157|UniProtKB=O00154 O00154 ACOT7 PTHR11049:SF27 ACYL COENZYME A THIOESTER HYDROLASE CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;thiolester hydrolase activity#GO:0016790;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;fatty acid biosynthetic process#GO:0006633;metabolic process#GO:0008152;long-chain fatty acid metabolic process#GO:0001676;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 esterase#PC00097 HUMAN|HGNC=7807|UniProtKB=Q8N5V2 Q8N5V2 NGEF PTHR12845:SF8 GUANINE NUCLEOTIDE EXCHANGE FACTOR EPHEXIN-1 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=215|UniProtKB=P78325 P78325 ADAM8 PTHR11905:SF20 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 8 metallopeptidase activity#GO:0008237;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of cell-cell adhesion#GO:0022407;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;regulation of localization#GO:0032879;positive regulation of proteolysis#GO:0045862;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of cellular component movement#GO:0051270;macromolecule catabolic process#GO:0009057;membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;positive regulation of locomotion#GO:0040017;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell adhesion#GO:0007155;membrane protein ectodomain proteolysis#GO:0006509;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;response to stress#GO:0006950;regulation of cellular process#GO:0050794;movement of cell or subcellular component#GO:0006928;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of locomotion#GO:0040012;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;biological adhesion#GO:0022610;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;inflammatory response#GO:0006954;positive regulation of leukocyte migration#GO:0002687;positive regulation of metabolic process#GO:0009893;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;catabolic process#GO:0009056;regulation of immune system process#GO:0002682;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;regulation of cell adhesion#GO:0030155;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;regulation of cell motility#GO:2000145;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of cell migration#GO:0030335;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 membrane protein complex#GO:0098796;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 metalloprotease#PC00153 HUMAN|HGNC=1361|UniProtKB=Q8N6M6 Q8N6M6 AOPEP PTHR46627:SF1 AMINOPEPTIDASE O AMINOPEPTIDASE O intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 HUMAN|HGNC=2755|UniProtKB=O75618 O75618 DEDD PTHR15205:SF2 DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;extrinsic apoptotic signaling pathway via death domain receptors#GO:0008625;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;cell death#GO:0008219;biological regulation#GO:0065007;signaling#GO:0023052 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26191|UniProtKB=Q9H6B1 Q9H6B1 ZNF385D PTHR23067:SF12 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN ZINC FINGER PROTEIN 385D membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=30536|UniProtKB=Q96GE9 Q96GE9 DMAC1 PTHR36469:SF1 DISTAL MEMBRANE-ARM ASSEMBLY COMPLEX PROTEIN 1 DISTAL MEMBRANE-ARM ASSEMBLY COMPLEX PROTEIN 1 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 HUMAN|HGNC=20472|UniProtKB=O15116 O15116 LSM1 PTHR15588:SF8 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;deadenylation-dependent decapping of nuclear-transcribed mRNA#GO:0000290;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA splicing factor#PC00148 HUMAN|HGNC=20852|UniProtKB=Q96S15 Q96S15 WDR24 PTHR46200:SF1 GATOR COMPLEX PROTEIN WDR24 GATOR COMPLEX PROTEIN WDR24 HUMAN|HGNC=29626|UniProtKB=Q8TDS7 Q8TDS7 MRGPRD PTHR11334:SF57 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MEMBER D signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=9081|UniProtKB=Q02809 Q02809 PLOD1 PTHR10730:SF5 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE 1 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=12209|UniProtKB=A0A5B6 A0A5B6 TRBV28 PTHR23268:SF73 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 28 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=784|UniProtKB=P15336 P15336 ATF2 PTHR19304:SF9 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic leucine zipper transcription factor#PC00056 Ras Pathway#P04393>ATF2#P04548;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Gonadotropin-releasing hormone receptor pathway#P06664>ATF2#P06732;Apoptosis signaling pathway#P00006>ATF#P00302;Oxidative stress response#P00046>ATF2#P01126;CCKR signaling map#P06959>ATF2#P07078 HUMAN|HGNC=16865|UniProtKB=Q92561 Q92561 PHYHIP PTHR15698:SF9 PROTEIN CBG15099 PHYTANOYL-COA HYDROXYLASE-INTERACTING PROTEIN HUMAN|HGNC=14054|UniProtKB=Q9P015 Q9P015 MRPL15 PTHR12934:SF11 50S RIBOSOMAL PROTEIN L15 39S RIBOSOMAL PROTEIN L15, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202 HUMAN|HGNC=19005|UniProtKB=Q9C098 Q9C098 DCLK3 PTHR24347:SF427 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE DCLK3 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=14994|UniProtKB=Q8NGY7 Q8NGY7 OR10J6P PTHR24247:SF103 5-HYDROXYTRYPTAMINE RECEPTOR OLFACTORY RECEPTOR 10J6-RELATED cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=37281|UniProtKB=C9JRZ8 C9JRZ8 AKR1B15 PTHR11732:SF197 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER B15 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 reductase#PC00198 HUMAN|HGNC=25905|UniProtKB=Q96EX2 Q96EX2 RNFT2 PTHR15860:SF2 UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN RING FINGER AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 HUMAN|HGNC=23601|UniProtKB=Q701N2 Q701N2 KRTAP5-5 PTHR23262:SF173 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 5-5 HUMAN|HGNC=17333|UniProtKB=Q8NEY3 Q8NEY3 SPATA4 PTHR12509:SF8 SPERMATOGENESIS-ASSOCIATED 4-RELATED SPERMATOGENESIS-ASSOCIATED PROTEIN 4 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=12916|UniProtKB=P52740 P52740 ZNF132 PTHR24377:SF636 IP01015P-RELATED ZINC FINGER PROTEIN 132 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=27256|UniProtKB=A6NEF3 A6NEF3 GOLGA6L4 PTHR23143:SF19 TRICHOHYALIN-RELATED GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 10-RELATED actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=19889|UniProtKB=Q9NVX2 Q9NVX2 NLE1 PTHR19848:SF5 WD40 REPEAT PROTEIN NOTCHLESS PROTEIN HOMOLOG 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex biogenesis#GO:0022613;ribonucleoprotein complex assembly#GO:0022618;biological regulation#GO:0065007;ribosome biogenesis#GO:0042254;signaling#GO:0023052;protein-containing complex subunit organization#GO:0043933;Notch signaling pathway#GO:0007219 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=10027|UniProtKB=P04090 P04090 RLN2 PTHR12004:SF13 RELAXIN PRORELAXIN H2 peptide hormone#PC00179 HUMAN|HGNC=5610|UniProtKB=P01767 P01767 IGHV3-53 PTHR23266:SF204 IMMUNOGLOBULIN HEAVY CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=18559|UniProtKB=Q9H5Q4 Q9H5Q4 TFB2M PTHR11727:SF13 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 2, MITOCHONDRIAL N-methyltransferase activity#GO:0008170;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;methyltransferase activity#GO:0008168;catalytic activity, acting on RNA#GO:0140098;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;RNA polymerase binding#GO:0070063;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;mitochondrial gene expression#GO:0140053;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;ncRNA metabolic process#GO:0034660;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;mitochondrial RNA metabolic process#GO:0000959;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;methylation#GO:0032259;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;aromatic compound biosynthetic process#GO:0019438;RNA methylation#GO:0001510 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 HUMAN|HGNC=26433|UniProtKB=Q96NC0 Q96NC0 ZMAT2 PTHR45986:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 2 ZINC FINGER MATRIN-TYPE PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=8514|UniProtKB=O75508 O75508 CLDN11 PTHR12002:SF6 CLAUDIN CLAUDIN-11 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=30454|UniProtKB=Q9NSQ0 Q9NSQ0 RRP7BP PTHR13191:SF0 RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 RNA metabolism protein#PC00031 HUMAN|HGNC=31715|UniProtKB=A0A5S8K742 A0A5S8K742 GLRA4 PTHR18945:SF211 NEUROTRANSMITTER GATED ION CHANNEL GLYCINE RECEPTOR ALPHA 4 (PSEUDOGENE) signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103 signal transduction#GO:0007165;transport#GO:0006810;system process#GO:0003008;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;anion transmembrane transport#GO:0098656;regulation of biological process#GO:0050789;inorganic anion transmembrane transport#GO:0098661;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;anion transport#GO:0006820;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;signaling#GO:0023052;inorganic anion transport#GO:0015698;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=28967|UniProtKB=Q14146 Q14146 URB2 PTHR15682:SF2 UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6319|UniProtKB=Q9Y496 Q9Y496 KIF3A PTHR24115:SF472 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3A pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=7775|UniProtKB=O95644 O95644 NFATC1 PTHR12533:SF5 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772 positive regulation of gene expression#GO:0010628;calcium-mediated signaling#GO:0019722;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252 Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Wnt signaling pathway#P00057>NFAT#P01452;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367 HUMAN|HGNC=31710|UniProtKB=Q5JXB2 Q5JXB2 UBE2NL PTHR24068:SF138 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 N-LIKE-RELATED ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;protein K63-linked ubiquitination#GO:0070534;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Toll receptor signaling pathway#P00054>Ubc13#P01381 HUMAN|HGNC=20487|UniProtKB=Q6NXP6 Q6NXP6 NOXRED1 PTHR11645:SF58 PYRROLINE-5-CARBOXYLATE REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 reductase#PC00198 HUMAN|HGNC=17733|UniProtKB=Q9ULM0 Q9ULM0 PLEKHH1 PTHR22903:SF4 PLEKHH PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 1 HUMAN|HGNC=16665|UniProtKB=Q9ULZ1 Q9ULZ1 APLN PTHR15953:SF0 APELIN APELIN HUMAN|HGNC=22082|UniProtKB=Q3ZAQ7 Q3ZAQ7 VMA21 PTHR31792:SF3 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 VACUOLAR ATPASE ASSEMBLY INTEGRAL MEMBRANE PROTEIN VMA21 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=13870|UniProtKB=O43809 O43809 NUDT21 PTHR13047:SF0 PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=23667|UniProtKB=Q5VT28 Q5VT28 FAM27C PTHR38818:SF4 PROTEIN FAM27A/B/C PROTEIN FAM27A/B/C HUMAN|HGNC=17692|UniProtKB=Q9HAT0 Q9HAT0 ROPN1 PTHR14952:SF18 ROPPORIN-1-LIKE PROTEIN ROPPORIN-1A HUMAN|HGNC=18725|UniProtKB=Q68G75 Q68G75 LEMD1 PTHR12019:SF12 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN LEM DOMAIN-CONTAINING PROTEIN 1 peptide hormone#PC00179 HUMAN|HGNC=18126|UniProtKB=Q9ULT6 Q9ULT6 ZNRF3 PTHR16200:SF3 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE ZNRF3 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=8211|UniProtKB=Q8NGS1 Q8NGS1 OR1J4 PTHR48001:SF10 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1J4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=9316|UniProtKB=P48454 P48454 PPP3CC PTHR45673:SF2 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT GAMMA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 protein phosphatase#PC00195 T cell activation#P00053>Calcineurin#P01315;B cell activation#P00010>Calcineurin#P00386;Wnt signaling pathway#P00057>Calcineurin#P01446 HUMAN|HGNC=28487|UniProtKB=Q8NHS2 Q8NHS2 GOT1L1 PTHR11879:SF6 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, CYTOPLASMIC 2-RELATED transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transaminase#PC00216 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 HUMAN|HGNC=10924|UniProtKB=O15427 O15427 SLC16A3 PTHR11360:SF27 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=21176|UniProtKB=Q9NWS8 Q9NWS8 RMND1 PTHR16255:SF1 REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;mitochondrial translation#GO:0032543;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;positive regulation of cellular protein metabolic process#GO:0032270;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 HUMAN|HGNC=29647|UniProtKB=Q5TCQ9 Q5TCQ9 MAGI3 PTHR10316:SF10 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9022|UniProtKB=P55347 P55347 PKNOX1 PTHR11850:SF80 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN PKNOX1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;tube morphogenesis#GO:0035239;cellular nitrogen compound biosynthetic process#GO:0044271;vasculature development#GO:0001944;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;angiogenesis#GO:0001525;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 Gonadotropin-releasing hormone receptor pathway#P06664>Prep1#P06829 HUMAN|HGNC=347|UniProtKB=Q09666 Q09666 AHNAK PTHR23348:SF41 PERIAXIN/AHNAK NEUROBLAST DIFFERENTIATION-ASSOCIATED PROTEIN AHNAK cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;myofibril#GO:0030016;contractile fiber#GO:0043292;intracellular organelle#GO:0043229 HUMAN|HGNC=31792|UniProtKB=Q8NFC6 Q8NFC6 BOD1L1 PTHR31532:SF10 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 FAMILY MEMBER BIORIENTATION OF CHROMOSOMES IN CELL DIVISION PROTEIN 1-RELATED HUMAN|HGNC=33710|UniProtKB=Q6NVV7 Q6NVV7 CDPF1 PTHR31849:SF1 CYSTEINE-RICH PDF MOTIF DOMAIN-CONTAINING PROTEIN 1 CYSTEINE-RICH DPF MOTIF DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=333|UniProtKB=P01019 P01019 AGT PTHR11461:SF331 SERINE PROTEASE INHIBITOR, SERPIN ANGIOTENSINOGEN serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>AngII#P05935 HUMAN|HGNC=14312|UniProtKB=Q9P021 Q9P021 CRIPT PTHR11805:SF1 CYSTEINE-RICH PDZ-BINDING PROTEIN CYSTEINE-RICH PDZ-BINDING PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;microtubule binding#GO:0008017;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 HUMAN|HGNC=9449|UniProtKB=P04156 P04156 PRNP PTHR10502:SF134 ANNEXIN MAJOR PRION PROTEIN calcium-binding protein#PC00060 HUMAN|HGNC=1180|UniProtKB=Q15777 Q15777 MPPED2 PTHR12905:SF13 METALLOPHOSPHOESTERASE METALLOPHOSPHOESTERASE MPPED2 esterase#PC00097 HUMAN|HGNC=18588|UniProtKB=Q92527 Q92527 ANKRD7 PTHR24118:SF86 POTE ANKYRIN DOMAIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 7 membrane traffic protein#PC00150 HUMAN|HGNC=14076|UniProtKB=Q96G23 Q96G23 CERS2 PTHR12560:SF7 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 2 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=20962|UniProtKB=Q9NT62 Q9NT62 ATG3 PTHR12866:SF2 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;autophagosome organization#GO:1905037;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;autophagy#GO:0006914;autophagy of nucleus#GO:0044804;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=6811|UniProtKB=O15481 O15481 MAGEB4 PTHR11736:SF22 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B4 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29537|UniProtKB=Q99687 Q99687 MEIS3 PTHR11850:SF190 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN MEIS3 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;brain development#GO:0007420;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;sensory system development#GO:0048880;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;visual system development#GO:0150063;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=21642|UniProtKB=Q5ST30 Q5ST30 VARS2 PTHR11946:SF71 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=725|UniProtKB=Q13508 Q13508 ART3 PTHR10339:SF4 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 3 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=14618|UniProtKB=Q8WTP9 Q8WTP9 XAGE3 PTHR14047:SF4 P ANTIGEN FAMILY MEMBER 5-RELATED X ANTIGEN FAMILY MEMBER 3 HUMAN|HGNC=6465|UniProtKB=Q8IVT5 Q8IVT5 KSR1 PTHR23257:SF716 SERINE-THREONINE PROTEIN KINASE KINASE SUPPRESSOR OF RAS 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>KSR-1#P06842 HUMAN|HGNC=10831|UniProtKB=Q99962 Q99962 SH3GL2 PTHR14167:SF50 SH3 DOMAIN-CONTAINING ENDOPHILIN-A1 HUMAN|HGNC=12305|UniProtKB=Q15643 Q15643 TRIP11 PTHR18921:SF2 MYOSIN HEAVY CHAIN - RELATED THYROID RECEPTOR-INTERACTING PROTEIN 11 actin binding motor protein#PC00040 HUMAN|HGNC=3804|UniProtKB=Q9UJU5 Q9UJU5 FOXD3 PTHR11829:SF361 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=18811|UniProtKB=Q8NFL0 Q8NFL0 B3GNT7 PTHR11214:SF93 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;cellular polysaccharide biosynthetic process#GO:0033692;cellular polysaccharide metabolic process#GO:0044264;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=5999|UniProtKB=Q9HB29 Q9HB29 IL1RL2 PTHR11890:SF9 INTERLEUKIN-1 RECEPTOR FAMILY MEMBER INTERLEUKIN-1 RECEPTOR-LIKE 2 regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of inflammatory response#GO:0050727;response to external stimulus#GO:0009605;regulation of response to external stimulus#GO:0032101;response to stress#GO:0006950;regulation of defense response#GO:0031347;biological regulation#GO:0065007;regulation of response to stress#GO:0080134;defense response#GO:0006952;inflammatory response#GO:0006954 transmembrane signal receptor#PC00197 HUMAN|HGNC=16274|UniProtKB=Q96J86 Q96J86 CYYR1 PTHR38490:SF1 CYSTEINE AND TYROSINE-RICH PROTEIN 1 CYSTEINE AND TYROSINE-RICH PROTEIN 1 HUMAN|HGNC=6996|UniProtKB=Q06413 Q06413 MEF2C PTHR11945:SF25 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2C cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;histone deacetylase binding#GO:0042826;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;CCKR signaling map#P06959>MEF2C#P07222;Oxidative stress response#P00046>MEF-2#P01128 HUMAN|HGNC=14670|UniProtKB=Q9P218 Q9P218 COL20A1 PTHR24020:SF39 COLLAGEN ALPHA COLLAGEN ALPHA-1(XX) CHAIN extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=2024|UniProtKB=P51797 P51797 CLCN6 PTHR11689:SF158 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER CHLORIDE TRANSPORT PROTEIN 6 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ion channel#PC00133 HUMAN|HGNC=25615|UniProtKB=Q1X8D7 Q1X8D7 LRRC36 PTHR23311:SF6 HEAT SHOCK REGULATED 2 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 36 HUMAN|HGNC=20967|UniProtKB=Q96RE7 Q96RE7 NACC1 PTHR46105:SF3 AGAP004733-PA NUCLEUS ACCUMBENS-ASSOCIATED PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=4688|UniProtKB=P25092 P25092 GUCY2C PTHR11920:SF347 GUANYLYL CYCLASE HEAT-STABLE ENTEROTOXIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;organophosphate biosynthetic process#GO:0090407;cyclic nucleotide metabolic process#GO:0009187;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 guanylate cyclase#PC00114 HUMAN|HGNC=17847|UniProtKB=Q15208 Q15208 STK38 PTHR24356:SF221 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE 38 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=3314|UniProtKB=Q14576 Q14576 ELAVL3 PTHR10352:SF15 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 3 translation initiation factor#PC00224 HUMAN|HGNC=24051|UniProtKB=Q6ZN18 Q6ZN18 AEBP2 PTHR46541:SF1 ZINC FINGER PROTEIN AEBP2 ZINC FINGER PROTEIN AEBP2 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=9066|UniProtKB=P16885 P16885 PLCG2 PTHR10336:SF25 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2 regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;positive regulation of locomotion#GO:0040017;regulation of localization#GO:0032879;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular component movement#GO:0051272;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of biological process#GO:0050789;positive regulation of cell migration#GO:0030335;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;positive regulation of cell motility#GO:2000147;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;cell migration#GO:0016477;locomotion#GO:0040011;positive regulation of biological process#GO:0048518;positive regulation of multicellular organismal process#GO:0051240 phospholipase#PC00186 VEGF signaling pathway#P00056>PLC-gamma#P01414;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;FGF signaling pathway#P00021>PLCgamma#P00638;B cell activation#P00010>PLC gamma2#P00388;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Angiogenesis#P00005>PLC-gamma#P00256;EGF receptor signaling pathway#P00018>PLCgamma#P00556;PDGF signaling pathway#P00047>PLCgamma#P01171;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412 HUMAN|HGNC=18521|UniProtKB=Q9NU39 Q9NU39 FOXD4L1 PTHR11829:SF350 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN D4-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=9857|UniProtKB=P61224 P61224 RAP1B PTHR24070:SF393 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1B-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;Ras protein signal transduction#GO:0007265;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;neurotransmitter secretion#GO:0007269;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of transport#GO:0051051;response to organonitrogen compound#GO:0010243;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;response to nitrogen compound#GO:1901698;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;regulation of trans-synaptic signaling#GO:0099177;export from cell#GO:0140352;vesicle fusion#GO:0006906;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;regulation of signaling#GO:0023051;transport#GO:0006810;cellular response to nitrogen compound#GO:1901699;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;neurotransmitter transport#GO:0006836;cellular response to organic cyclic compound#GO:0071407;signal release#GO:0023061;vesicle organization#GO:0016050;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;synaptic vesicle exocytosis#GO:0016079;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;response to chemical#GO:0042221;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#P06803;Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#G06881;Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#G06668;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 HUMAN|HGNC=6551|UniProtKB=Q9UJU2 Q9UJU2 LEF1 PTHR10373:SF11 TRANSCRIPTION FACTOR 7 FAMILY MEMBER LYMPHOID ENHANCER-BINDING FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143;Cadherin signaling pathway#P00012>TCF/LEF#P00465 HUMAN|HGNC=19357|UniProtKB=Q9H3C7 Q9H3C7 GGNBP2 PTHR13601:SF2 GAMETOGENETIN-BINDING PROTEIN 2 GAMETOGENETIN-BINDING PROTEIN 2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28532|UniProtKB=Q8IV33 Q8IV33 KIAA0825 PTHR33960:SF1 SIMILAR TO KIAA0825 PROTEIN SIMILAR TO KIAA0825 PROTEIN HUMAN|HGNC=4826|UniProtKB=Q6B0K9 Q6B0K9 HBM PTHR11442:SF8 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT MU small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;intracellular#GO:0005622;extracellular region#GO:0005576 HUMAN|HGNC=44443|UniProtKB=C9J2P7 C9J2P7 USP17L15 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=23492|UniProtKB=Q17RR3 Q17RR3 PNLIPRP3 PTHR11610:SF100 LIPASE PANCREATIC LIPASE-RELATED PROTEIN 3 hydrolase activity#GO:0016787;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;catabolic process#GO:0009056;lipid catabolic process#GO:0016042;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 lipase#PC00143 HUMAN|HGNC=25328|UniProtKB=Q08AF8 Q08AF8 GOLGA8G PTHR10881:SF7 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8C-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=3542|UniProtKB=P12259 P12259 F5 PTHR24543:SF302 MULTICOPPER OXIDASE-RELATED COAGULATION FACTOR V oxidoreductase#PC00176 Blood coagulation#P00011>FVa#P00435;Blood coagulation#P00011>FV#P00432 HUMAN|HGNC=6388|UniProtKB=P52732 P52732 KIF11 PTHR47970:SF12 KINESIN-LIKE PROTEIN KIF11 KINESIN-LIKE PROTEIN KIF11 pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;catalytic activity#GO:0003824;ATP-dependent microtubule motor activity, plus-end-directed#GO:0008574;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 microtubule binding motor protein#PC00156 HUMAN|HGNC=20120|UniProtKB=Q17RC7 Q17RC7 EXOC3L4 PTHR21292:SF14 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3-LIKE PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 vesicle fusion#GO:0006906;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;vesicle organization#GO:0016050;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 membrane traffic protein#PC00150 HUMAN|HGNC=24079|UniProtKB=A6QL64 A6QL64 ANKRD36 PTHR24147:SF50 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 36A-RELATED HUMAN|HGNC=28596|UniProtKB=Q8NCR0 Q8NCR0 B3GALNT2 PTHR11214:SF219 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 2 glycosyltransferase#PC00111 HUMAN|HGNC=17496|UniProtKB=Q5VSY0 Q5VSY0 GKAP1 PTHR14899:SF0 G KINASE ANCHORING PROTEIN 1 G KINASE-ANCHORING PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|Gene=HERVK_113|UniProtKB=Q902F9 Q902F9 HERVK_113 PTHR34313:SF2 ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED ENDOGENOUS RETROVIRUS GROUP K MEMBER 113 ENV POLYPROTEIN-RELATED viral or transposable element protein#PC00237 HUMAN|HGNC=4055|UniProtKB=P12956 P12956 XRCC6 PTHR12604:SF5 KU AUTOANTIGEN DNA HELICASE X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;cellular response to abiotic stimulus#GO:0071214;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;response to ionizing radiation#GO:0010212;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;biological regulation#GO:0065007;cellular response to stress#GO:0033554;cellular response to environmental stimulus#GO:0104004;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;nuclear chromosome, telomeric region#GO:0000784;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 DNA helicase#PC00011 HUMAN|HGNC=29125|UniProtKB=Q9UQ16 Q9UQ16 DNM3 PTHR11566:SF54 DYNAMIN DYNAMIN-3 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;organelle localization#GO:0051640;macromolecule localization#GO:0033036;receptor internalization#GO:0031623;membrane organization#GO:0061024;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;synaptic vesicle transport#GO:0048489;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;membrane fission#GO:0090148;vesicle localization#GO:0051648;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;protein transport#GO:0015031;biological regulation#GO:0065007;protein polymerization#GO:0051258;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;regulation of synapse structure or activity#GO:0050803;mitochondrial fission#GO:0000266;vesicle-mediated transport in synapse#GO:0099003;protein-containing complex localization#GO:0031503 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;non-membrane-bounded organelle#GO:0043228;membrane coat#GO:0030117;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;mitochondrial envelope#GO:0005740;plasma membrane region#GO:0098590;postsynapse#GO:0098794;coated membrane#GO:0048475;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;envelope#GO:0031975;membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;mitochondrial membrane#GO:0031966;intracellular vesicle#GO:0097708;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;mitochondrion#GO:0005739;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=12691|UniProtKB=P15311 P15311 EZR PTHR23281:SF13 MERLIN/MOESIN/EZRIN/RADIXIN EZRIN actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=18987|UniProtKB=Q9BU02 Q9BU02 THTPA PTHR14586:SF1 THIAMINE-TRIPHOSPHATASE THIAMINE-TRIPHOSPHATASE cation binding#GO:0043169;pyrophosphatase activity#GO:0016462;magnesium ion binding#GO:0000287;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;metal ion binding#GO:0046872;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;sulfur compound metabolic process#GO:0006790;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphatase#PC00181 Thiamin metabolism#P02780>Thiamine triphosphatase#P03184 HUMAN|HGNC=13495|UniProtKB=Q5VT40 Q5VT40 FAM78B PTHR31655:SF0 FAMILY NOT NAMED PROTEIN FAM78B HUMAN|HGNC=30100|UniProtKB=Q9NZ42 Q9NZ42 PSENEN PTHR16318:SF0 GAMMA-SECRETASE SUBUNIT PEN-2 GAMMA-SECRETASE SUBUNIT PEN-2 membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane protein complex#GO:0098797 Alzheimer disease-amyloid secretase pathway#P00003>Pen-2#P00089;Alzheimer disease-presenilin pathway#P00004>Pen-2#P00149 HUMAN|HGNC=19703|UniProtKB=Q6PHR2 Q6PHR2 ULK3 PTHR24348:SF65 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE/THREONINE-PROTEIN KINASE ULK3 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=28423|UniProtKB=Q96MF2 Q96MF2 STAC3 PTHR15135:SF2 STAC SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN 3 positive regulation of ion transport#GO:0043270;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of metal ion transport#GO:0010959;system process#GO:0003008;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of molecular function#GO:0044093;positive regulation of cation channel activity#GO:2001259;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;establishment of localization#GO:0051234;skeletal muscle contraction#GO:0003009;regulation of molecular function#GO:0065009;divalent inorganic cation transport#GO:0072511;positive regulation of transmembrane transport#GO:0034764;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;protein localization to plasma membrane#GO:0072659;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;protein localization to membrane#GO:0072657;calcium ion transmembrane transport#GO:0070588;regulation of protein localization to membrane#GO:1905475;ion transport#GO:0006811;regulation of calcium ion transport#GO:0051924;positive regulation of ion transmembrane transporter activity#GO:0032414;positive regulation of transport#GO:0051050;positive regulation of calcium ion transport#GO:0051928;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;striated muscle contraction#GO:0006941;ion transmembrane transport#GO:0034220;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;protein localization to cell periphery#GO:1990778;regulation of ion transmembrane transport#GO:0034765;cellular macromolecule localization#GO:0070727;positive regulation of transporter activity#GO:0032411;regulation of cellular process#GO:0050794;positive regulation of ion transmembrane transport#GO:0034767;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of ion transport#GO:0043269;muscle system process#GO:0003012;muscle contraction#GO:0006936 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 HUMAN|HGNC=10658|UniProtKB=P18827 P18827 SDC1 PTHR10915:SF5 SYNDECAN SYNDECAN-1 localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 transmembrane signal receptor#PC00197 HUMAN|HGNC=33113|UniProtKB=A8MUP2 A8MUP2 CSKMT PTHR12176:SF71 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN CITRATE SYNTHASE-LYSINE N-METHYLTRANSFERASE CSKMT, MITOCHONDRIAL-RELATED methyltransferase#PC00155 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=37283|UniProtKB=Q6ZQQ2 Q6ZQQ2 SPATA31D1 PTHR21859:SF12 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31D1 HUMAN|HGNC=18650|UniProtKB=Q86XZ4 Q86XZ4 SPATS2 PTHR15623:SF10 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2-RELATED SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=12781|UniProtKB=Q93097 Q93097 WNT2B PTHR12027:SF93 WNT RELATED PROTEIN WNT-2B receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=13992|UniProtKB=Q96JY6 Q96JY6 PDLIM2 PTHR24214:SF1 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 heart development#GO:0007507;circulatory system development#GO:0072359;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;muscle structure development#GO:0061061;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cytoskeleton organization#GO:0007010;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;Z disc#GO:0030018;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;contractile fiber#GO:0043292;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;adherens junction#GO:0005912;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=1506|UniProtKB=P51878 P51878 CASP5 PTHR10454:SF13 CASPASE CASPASE-5 cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=7662|UniProtKB=Q15080 Q15080 NCF4 PTHR15706:SF20 SH3 MULTIPLE DOMAIN NEUTROPHIL CYTOSOL FACTOR 4 HUMAN|HGNC=51507|UniProtKB=P0DTA3 P0DTA3 SPDYE11 PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=28709|UniProtKB=Q9BSA9 Q9BSA9 TMEM175 PTHR31462:SF5 ENDOSOMAL/LYSOSOMAL POTASSIUM CHANNEL TMEM175 ENDOSOMAL/LYSOSOMAL POTASSIUM CHANNEL TMEM175 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=28042|UniProtKB=A4D1B5 A4D1B5 GSAP PTHR13630:SF1 GAMMA-SECRETASE-ACTIVATING PROTEIN GAMMA-SECRETASE-ACTIVATING PROTEIN positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;positive regulation of cellular metabolic process#GO:0031325;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;regulation of cellular amide metabolic process#GO:0034248;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 protein-binding activity modulator#PC00095 HUMAN|HGNC=23490|UniProtKB=Q96E09 Q96E09 FAM122A PTHR22227:SF3 UNCHARACTERIZED PROTEIN FAM122A HUMAN|HGNC=220|UniProtKB=O75173 O75173 ADAMTS4 PTHR13723:SF38 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 4 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=21526|UniProtKB=Q8TDQ7 Q8TDQ7 GNPDA2 PTHR11280:SF9 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE ISOMERASE 2 identical protein binding#GO:0042802;hydrolase activity#GO:0016787;protein binding#GO:0005515;isomerase activity#GO:0016853;binding#GO:0005488;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;carbohydrate derivative catabolic process#GO:1901136;UDP-N-acetylglucosamine metabolic process#GO:0006047;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;organic acid catabolic process#GO:0016054;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule catabolic process#GO:0044282;amino sugar catabolic process#GO:0046348;amino sugar metabolic process#GO:0006040;aromatic compound biosynthetic process#GO:0019438;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 isomerase#PC00135 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 HUMAN|HGNC=3313|UniProtKB=Q12926 Q12926 ELAVL2 PTHR10352:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G ELAV-LIKE PROTEIN 2 translation initiation factor#PC00224 HUMAN|HGNC=17848|UniProtKB=Q9Y2H1 Q9Y2H1 STK38L PTHR24356:SF160 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE 38-LIKE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=2299|UniProtKB=P15086 P15086 CPB1 PTHR11705:SF20 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE B hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=2394|UniProtKB=P05813 P05813 CRYBA1 PTHR11818:SF8 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A3 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=26054|UniProtKB=Q96DW6 Q96DW6 SLC25A38 PTHR46181:SF3 MITOCHONDRIAL GLYCINE TRANSPORTER MITOCHONDRIAL GLYCINE TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=28871|UniProtKB=Q9BTL4 Q9BTL4 IER2 PTHR15895:SF4 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 2 PROTEIN HUMAN|HGNC=22962|UniProtKB=Q71F56 Q71F56 MED13L PTHR48249:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13-LIKE molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=2689|UniProtKB=P09172 P09172 DBH PTHR10157:SF29 DOPAMINE BETA HYDROXYLASE RELATED DOPAMINE BETA-HYDROXYLASE cation binding#GO:0043169;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497 cellular aromatic compound metabolic process#GO:0006725;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;catecholamine metabolic process#GO:0006584;biosynthetic process#GO:0009058;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;aromatic compound catabolic process#GO:0019439;regulation of neurotransmitter levels#GO:0001505;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;extracellular region#GO:0005576;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 hydroxylase#PC00122 Adrenaline and noradrenaline biosynthesis#P00001>DBH#P00063;Dopamine receptor mediated signaling pathway#P05912>DBH#P05955 HUMAN|HGNC=23357|UniProtKB=Q9ULC4 Q9ULC4 MCTS1 PTHR22798:SF12 MCT-1 PROTEIN MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 translation initiation factor#PC00224 HUMAN|HGNC=10473|UniProtKB=Q13761 Q13761 RUNX3 PTHR11950:SF43 RUNT RELATED RUNT-RELATED TRANSCRIPTION FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;hematopoietic or lymphoid organ development#GO:0048534;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Runt transcription factor#PC00254 HUMAN|HGNC=23133|UniProtKB=Q9BTE0 Q9BTE0 NAT9 PTHR13256:SF16 N-ACETYLTRANSFERASE 9 N-ACETYLTRANSFERASE 9 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein acylation#GO:0043543;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=14938|UniProtKB=Q969N2 Q969N2 PIGT PTHR12959:SF11 GPI TRANSAMIDASE COMPONENT PIG-T-RELATED GPI TRANSAMIDASE COMPONENT PIG-T lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;membrane lipid biosynthetic process#GO:0046467;GPI anchor metabolic process#GO:0006505;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;GPI anchor biosynthetic process#GO:0006506;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=14216|UniProtKB=Q9H2C1 Q9H2C1 LHX5 PTHR24208:SF115 LIM/HOMEOBOX PROTEIN LHX LIM/HOMEOBOX PROTEIN LHX5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=33813|UniProtKB=Q6ZUF6 Q6ZUF6 LINC00336 PTHR12138:SF128 PRIMATE-EXPANDED PROTEIN FAMILY ZINC FINGER PROTEIN ENSP00000375192 HUMAN|HGNC=24925|UniProtKB=Q9BWH2 Q9BWH2 FUNDC2 PTHR21346:SF5 FUN14 DOMAIN CONTAINING FUN14 DOMAIN-CONTAINING PROTEIN 2 process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;mitochondrion organization#GO:0007005;cellular process#GO:0009987;organelle disassembly#GO:1903008;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;integral component of mitochondrial outer membrane#GO:0031307 HUMAN|HGNC=12852|UniProtKB=P61981 P61981 YWHAG PTHR18860:SF22 14-3-3 PROTEIN 14-3-3 PROTEIN GAMMA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539 HUMAN|HGNC=29634|UniProtKB=Q96KG7 Q96KG7 MEGF10 PTHR24035:SF136 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 10 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;phagocytosis#GO:0006909;apoptotic cell clearance#GO:0043277;transport#GO:0006810 extracellular matrix protein#PC00102 HUMAN|HGNC=13498|UniProtKB=Q9Y2Q1 Q9Y2Q1 ZNF257 PTHR24384:SF127 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 257 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=34409|UniProtKB=A6NHN6 A6NHN6 NPIPB15 PTHR15438:SF4 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER B15-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11515|UniProtKB=O15178 O15178 TBXT PTHR11267:SF83 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR T cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;ectoderm formation#GO:0001705;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;mesoderm morphogenesis#GO:0048332;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;ectoderm development#GO:0007398;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;heart development#GO:0007507;epithelium development#GO:0060429;mesoderm formation#GO:0001707;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;endoderm formation#GO:0001706;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heart morphogenesis#GO:0003007;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;anatomical structure formation involved in morphogenesis#GO:0048646;mesoderm development#GO:0007498;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;formation of primary germ layer#GO:0001704;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 HUMAN|HGNC=29547|UniProtKB=Q8NEM2 Q8NEM2 SHCBP1 PTHR14695:SF8 SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED SHC SH2 DOMAIN-BINDING PROTEIN 1 fibroblast growth factor receptor signaling pathway#GO:0008543;male gamete generation#GO:0048232;cell division#GO:0051301;signal transduction#GO:0007165;cellular process involved in reproduction in multicellular organism#GO:0022412;membrane organization#GO:0061024;response to growth factor#GO:0070848;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;meiotic cell cycle process#GO:1903046;spermatogenesis#GO:0007283;cytoskeleton-dependent cytokinesis#GO:0061640;reproductive process#GO:0022414;male meiotic nuclear division#GO:0007140;multi-organism reproductive process#GO:0044703;signaling#GO:0023052;cytokinesis#GO:0000910;multicellular organismal reproductive process#GO:0048609;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;gamete generation#GO:0007276;membrane fission#GO:0090148;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;multicellular organism reproduction#GO:0032504;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;reproduction#GO:0000003;response to chemical#GO:0042221;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;sexual reproduction#GO:0019953;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;multicellular organismal process#GO:0032501 HUMAN|HGNC=6430|UniProtKB=P05783 P05783 KRT18 PTHR23239:SF349 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 18 HUMAN|HGNC=16809|UniProtKB=Q9HAU4 Q9HAU4 SMURF2 PTHR11254:SF300 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF2 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;protein catabolic process#GO:0030163;regulation of BMP signaling pathway#GO:0030510;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;cellular response to endogenous stimulus#GO:0071495;protein modification by small protein conjugation or removal#GO:0070647;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;positive regulation of catabolic process#GO:0009896;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;negative regulation of signal transduction#GO:0009968;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;regulation of protein catabolic process#GO:0042176;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;negative regulation of BMP signaling pathway#GO:0030514;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cellular protein catabolic process#GO:0044257;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490;TGF-beta signaling pathway#P00052>Smurfs#P01279 HUMAN|HGNC=23443|UniProtKB=A6NDA9 A6NDA9 LRIT2 PTHR45842:SF14 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT, IMMUNOGLOBULIN-LIKE DOMAIN AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=11616|UniProtKB=Q15170 Q15170 TCEAL1 PTHR14754:SF12 TRANSCRIPTION ELONGATION FACTOR A TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 1 general transcription factor#PC00259 HUMAN|HGNC=33504|UniProtKB=Q6UWF3 Q6UWF3 SCIMP PTHR12044:SF11 BCL2 INTERACTING MEDIATOR OF CELL DEATH SLP ADAPTER AND CSK-INTERACTING MEMBRANE PROTEIN meiosis I cell cycle phase#GO:0098764;meiotic cell cycle#GO:0051321;nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;cellular component organization#GO:0016043;cellular process#GO:0009987;M phase#GO:0000279;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;meiotic nuclear division#GO:0140013;meiotic cell cycle process#GO:1903046;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;cell cycle phase#GO:0022403;meiosis I#GO:0007127 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=1700|UniProtKB=P33681 P33681 CD80 PTHR25466:SF4 T-LYMPHOCYTE ACTIVATION ANTIGEN T-LYMPHOCYTE ACTIVATION ANTIGEN CD80 response to external biotic stimulus#GO:0043207;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to molecule of bacterial origin#GO:0002237;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;mononuclear cell proliferation#GO:0032943;negative regulation of T cell proliferation#GO:0042130;response to oxygen-containing compound#GO:1901700;negative regulation of T cell activation#GO:0050868;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;cell adhesion#GO:0007155;response to lipopolysaccharide#GO:0032496;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to lipopolysaccharide#GO:0071222;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;cellular response to lipid#GO:0071396;leukocyte cell-cell adhesion#GO:0007159;T cell proliferation#GO:0042098;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of leukocyte cell-cell adhesion#GO:1903039;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;regulation of T cell proliferation#GO:0042129;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>B7#P01337 HUMAN|HGNC=6423|UniProtKB=P08779 P08779 KRT16 PTHR23239:SF105 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 16 HUMAN|HGNC=20761|UniProtKB=Q68DK2 Q68DK2 ZFYVE26 PTHR46591:SF1 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 26 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 26 phosphatidylinositol-3-phosphate binding#GO:0032266;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cell division#GO:0051301;membrane fission#GO:0090148;membrane organization#GO:0061024;cell cycle process#GO:0022402;cellular component organization#GO:0016043;regulation of cell division#GO:0051302;cellular process#GO:0009987;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;cell cycle#GO:0007049;cytokinesis#GO:0000910;regulation of cytokinesis#GO:0032465 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;midbody#GO:0030496;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=18556|UniProtKB=Q8NFI4 Q8NFI4 ST13P5 PTHR45883:SF6 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN-RELATED protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chaperone-mediated protein folding#GO:0061077;protein folding#GO:0006457;protein-containing complex assembly#GO:0065003;'de novo' protein folding#GO:0006458;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 HUMAN|HGNC=7321|UniProtKB=O60682 O60682 MSC PTHR23349:SF62 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST MUSCULIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;muscle organ development#GO:0007517;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;muscle structure development#GO:0061061;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;striated muscle tissue development#GO:0014706;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;skeletal muscle organ development#GO:0060538;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;muscle tissue development#GO:0060537;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;skeletal muscle tissue development#GO:0007519;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=11916|UniProtKB=P19438 P19438 TNFRSF1A PTHR46861:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;tumor necrosis factor binding#GO:0043120;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to stress#GO:0006950;defense response#GO:0006952;inflammatory response#GO:0006954 cytoplasm#GO:0005737;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;membrane raft#GO:0045121;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;membrane region#GO:0098589;membrane microdomain#GO:0098857;intracellular organelle#GO:0043229;whole membrane#GO:0098805 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TNFR1#P00288 HUMAN|HGNC=23688|UniProtKB=Q86UU0 Q86UU0 BCL9L PTHR15185:SF3 BCL9 B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488;beta-catenin binding#GO:0008013 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;nucleobase-containing compound metabolic process#GO:0006139;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;aromatic compound biosynthetic process#GO:0019438;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;response to growth factor#GO:0070848;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;regulation of cellular response to transforming growth factor beta stimulus#GO:1903844;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;negative regulation of transforming growth factor beta receptor signaling pathway#GO:0030512;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 HUMAN|HGNC=16076|UniProtKB=Q9BYG4 Q9BYG4 PARD6G PTHR14102:SF3 PAR-6-RELATED PARTITIONING DEFECTIVE 6 HOMOLOG GAMMA Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;kinase binding#GO:0019900 establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;regulation of localization#GO:0032879;cellular component organization#GO:0016043;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;regulation of biological process#GO:0050789;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 tight junction#PC00214 HUMAN|HGNC=31257|UniProtKB=Q8NGX2 Q8NGX2 OR2T35 PTHR26453:SF18 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T2-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=25617|UniProtKB=Q96IZ5 Q96IZ5 RBM41 PTHR16105:SF2 UNCHARACTERIZED RNA-BINDING PROTEIN 41 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;snRNA binding#GO:0017069;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U12-type spliceosomal complex#GO:0005689 HUMAN|HGNC=19175|UniProtKB=Q8IZR5 Q8IZR5 CMTM4 PTHR22776:SF29 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=13055|UniProtKB=Q5VZL5 Q5VZL5 ZMYM4 PTHR45736:SF5 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 4 zinc finger transcription factor#PC00244 HUMAN|HGNC=37223|UniProtKB=P86478 P86478 PRR20E PTHR38819:SF1 PROLINE-RICH PROTEIN 20A-RELATED PROLINE-RICH PROTEIN 20A-RELATED HUMAN|HGNC=19287|UniProtKB=Q5MAI5 Q5MAI5 CDKL4 PTHR24056:SF120 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 4 cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=37182|UniProtKB=Q7RTZ2 Q7RTZ2 USP17L1 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=3761|UniProtKB=O43155 O43155 FLRT2 PTHR45712:SF16 AGAP008170-PA LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=23196|UniProtKB=Q8TAG9 Q8TAG9 EXOC6 PTHR12702:SF2 SEC15 EXOCYST COMPLEX COMPONENT 6 vesicle fusion#GO:0006906;vesicle-mediated transport to the plasma membrane#GO:0098876;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;exocytic process#GO:0140029;Golgi to plasma membrane transport#GO:0006893;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;vesicle organization#GO:0016050;export from cell#GO:0140352;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=26124|UniProtKB=Q8N3A8 Q8N3A8 PARP8 PTHR21328:SF3 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP8 protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;transferase activity, transferring glycosyl groups#GO:0016757;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;transferase activity, transferring pentosyl groups#GO:0016763;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554 envelope#GO:0031975;endoplasmic reticulum tubular network#GO:0071782;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=33778|UniProtKB=A6NI61 A6NI61 MYMK PTHR14319:SF7 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 POST-GPI ATTACHMENT TO PROTEINS FACTOR 6-RELATED cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=8756|UniProtKB=Q99447 Q99447 PCYT2 PTHR45780:SF2 ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE nucleotidyltransferase#PC00174 HUMAN|HGNC=29324|UniProtKB=Q8TEH3 Q8TEH3 DENND1A PTHR13196:SF22 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1A binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;small GTPase binding#GO:0031267;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137;Ras GTPase binding#GO:0017016;Ras guanyl-nucleotide exchange factor activity#GO:0005088;molecular function regulator#GO:0098772;protein binding#GO:0005515;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;Rab guanyl-nucleotide exchange factor activity#GO:0017112 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endocytic recycling#GO:0032456;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=4035|UniProtKB=Q16570 Q16570 ACKR1 PTHR14181:SF1 DUFFY ANTIGEN/CHEMOKINE RECEPTOR ATYPICAL CHEMOKINE RECEPTOR 1 transmembrane signal receptor#PC00197 HUMAN|HGNC=16790|UniProtKB=Q8IYK4 Q8IYK4 COLGALT2 PTHR10730:SF8 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN GALACTOSYLTRANSFERASE 2 transferase activity, transferring hexosyl groups#GO:0016758;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 protein modifying enzyme#PC00260 HUMAN|HGNC=4086|UniProtKB=Q8N1C3 Q8N1C3 GABRG1 PTHR18945:SF93 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-1 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;cell junction#GO:0030054;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=33765|UniProtKB=Q6ZMV7 Q6ZMV7 LEKR1 PTHR34251:SF1 LEUCINE-, GLUTAMATE- AND LYSINE-RICH PROTEIN 1 LEUCINE-, GLUTAMATE- AND LYSINE-RICH PROTEIN 1 HUMAN|HGNC=1385|UniProtKB=Q9NPB3 Q9NPB3 CABP2 PTHR45917:SF2 CALCIUM-BINDING PROTEIN 1-RELATED CALCIUM-BINDING PROTEIN 2 HUMAN|HGNC=5801|UniProtKB=A0A075B6S6 A0A075B6S6 IGKV2D-30 PTHR23267:SF475 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-30-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=15474|UniProtKB=Q9Y566 Q9Y566 SHANK1 PTHR24135:SF3 SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 1 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular component biogenesis#GO:0044085;regulation of dendrite development#GO:0050773;positive regulation of signal transduction#GO:0009967;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of transmembrane transporter activity#GO:0022898;central nervous system development#GO:0007417;positive regulation of cell development#GO:0010720;regulation of transporter activity#GO:0032409;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;regulation of multicellular organismal process#GO:0051239;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of synaptic plasticity#GO:0048167;cellular component organization or biogenesis#GO:0071840;regulation of ion transmembrane transport#GO:0034765;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;head development#GO:0060322;signal transduction#GO:0007165;neurogenesis#GO:0022008;regulation of signaling#GO:0023051;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of system process#GO:0044057;cation transport#GO:0006812;ionotropic glutamate receptor signaling pathway#GO:0035235;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;system development#GO:0048731;neuron differentiation#GO:0030182;cell junction assembly#GO:0034329;signaling#GO:0023052;cell-cell signaling#GO:0007267;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;transmembrane transport#GO:0055085;regulation of membrane potential#GO:0042391;cell morphogenesis#GO:0000902;nervous system process#GO:0050877;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of signaling receptor activity#GO:0010469;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;synapse assembly#GO:0007416;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;positive regulation of cellular component organization#GO:0051130;positive regulation of synaptic transmission#GO:0050806;synaptic transmission, glutamatergic#GO:0035249;cell projection organization#GO:0030030;dendrite development#GO:0016358;system process#GO:0003008;brain development#GO:0007420;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;dendritic spine organization#GO:0097061;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;regulation of dendritic spine development#GO:0060998;trans-synaptic signaling#GO:0099537;ion transmembrane transport#GO:0034220;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;neuromuscular junction development#GO:0007528;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;synapse organization#GO:0050808;neuron projection development#GO:0031175;modulation of chemical synaptic transmission#GO:0050804;regulation of cell projection organization#GO:0031344;neuron projection morphogenesis#GO:0048812;regulation of ion transport#GO:0043269;regulation of trans-synaptic signaling#GO:0099177;neuron development#GO:0048666;positive regulation of multicellular organismal process#GO:0051240;positive regulation of cell projection organization#GO:0031346;regulation of neurotransmitter receptor activity#GO:0099601;chemical synaptic transmission, postsynaptic#GO:0099565;animal organ development#GO:0048513;transport#GO:0006810;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;cation transmembrane transport#GO:0098655;positive regulation of response to stimulus#GO:0048584;regulation of transport#GO:0051049;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;positive regulation of neuron differentiation#GO:0045666;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;developmental growth#GO:0048589;regulation of cation transmembrane transport#GO:1904062;positive regulation of cell differentiation#GO:0045597;ion transport#GO:0006811;multicellular organism development#GO:0007275;regulation of AMPA receptor activity#GO:2000311;positive regulation of developmental process#GO:0051094;dendrite morphogenesis#GO:0048813;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;organelle assembly#GO:0070925;response to stimulus#GO:0050896;organelle organization#GO:0006996;cell junction organization#GO:0034330;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;generation of neurons#GO:0048699 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;membrane protein complex#GO:0098796;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;cell junction#GO:0030054;ion channel complex#GO:0034702;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;synaptic membrane#GO:0097060;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 Ionotropic glutamate receptor pathway#P00037>PSD95#P00999 HUMAN|HGNC=33234|UniProtKB=Q96GY3 Q96GY3 LIN37 PTHR31336:SF3 LIN37 HOMOLOG PROTEIN LIN-37 HOMOLOG HUMAN|HGNC=2885|UniProtKB=P55073 P55073 DIO3 PTHR11781:SF4 IODOTHYRONINE DEIODINASE THYROXINE 5-DEIODINASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=14324|UniProtKB=Q9BXJ1 Q9BXJ1 C1QTNF1 PTHR22923:SF63 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 1 HUMAN|HGNC=15855|UniProtKB=Q9NPY3 Q9NPY3 CD93 PTHR24034:SF83 EGF-LIKE DOMAIN-CONTAINING PROTEIN COMPLEMENT COMPONENT C1Q RECEPTOR cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;extracellular structure organization#GO:0043062;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix structural protein#PC00103 HUMAN|HGNC=28118|UniProtKB=P13994 P13994 CCDC130 PTHR12111:SF2 SPLICING FACTOR YJU2 COILED-COIL DOMAIN-CONTAINING PROTEIN 130 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=16364|UniProtKB=O15522 O15522 NKX2-8 PTHR24340:SF27 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN NKX-2.8 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=1712|UniProtKB=P32320 P32320 CDA PTHR11644:SF2 CYTIDINE DEAMINASE CYTIDINE DEAMINASE cation binding#GO:0043169;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;metal ion binding#GO:0046872;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;carbohydrate derivative catabolic process#GO:1901136;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;aromatic compound catabolic process#GO:0019439;small molecule catabolic process#GO:0044282;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;nucleobase-containing compound catabolic process#GO:0034655;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 deaminase#PC00088 Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;Pyrimidine Metabolism#P02771>Cytidine Deaminase#P03130 HUMAN|HGNC=32709|UniProtKB=A0A087WXS9 A0A087WXS9 TBC1D3I PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=23993|UniProtKB=Q4L235 Q4L235 AASDH PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME ligase#PC00142 HUMAN|HGNC=4384|UniProtKB=P63096 P63096 GNAI1 PTHR10218:SF227 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 Nicotine pharmacodynamics pathway#P06587>GNAI#P06609;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Endogenous cannabinoid signaling#P05730>Galpha#P05751;Gonadotropin-releasing hormone receptor pathway#P06664>gnai/o#P06773;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;GABA-B receptor II signaling#P05731>Gi/oalpha#P05757;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid prodynorphin pathway#P05916>G-protein#P06002;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proenkephalin pathway#P05915>G-protein#P05994;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai/q#P00873 HUMAN|HGNC=2357|UniProtKB=P34998 P34998 CRHR1 PTHR45620:SF2 PDF RECEPTOR-LIKE PROTEIN-RELATED CORTICOTROPIN-RELEASING FACTOR RECEPTOR 1 signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Cortocotropin releasing factor receptor signaling pathway#P04380>CRHR1#P04451 HUMAN|HGNC=25377|UniProtKB=Q96LZ2 Q96LZ2 MAGEB10 PTHR11736:SF157 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B10 scaffold/adaptor protein#PC00226 HUMAN|HGNC=31723|UniProtKB=Q24JQ0 Q24JQ0 TMEM241 PTHR11132:SF251 SOLUTE CARRIER FAMILY 35 TRANSMEMBRANE PROTEIN 241 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide-sugar transmembrane transporter activity#GO:0005338;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=13399|UniProtKB=O60422 O60422 ONECUT3 PTHR14057:SF34 TRANSCRIPTION FACTOR ONECUT ONE CUT DOMAIN FAMILY MEMBER 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=4551|UniProtKB=Q9NZ01 Q9NZ01 TECR PTHR10556:SF31 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE VERY-LONG-CHAIN ENOYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092 HUMAN|HGNC=15804|UniProtKB=Q9BRP0 Q9BRP0 OVOL2 PTHR10032:SF193 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS TRANSCRIPTION FACTOR OVO-LIKE 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;epithelium development#GO:0060429;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;epidermis development#GO:0008544;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;epidermal cell differentiation#GO:0009913;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11990|UniProtKB=Q02880 Q02880 TOP2B PTHR10169:SF36 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2-BETA cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;M phase#GO:0000279;meiotic chromosome separation#GO:0051307;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reciprocal meiotic recombination#GO:0007131;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;cell cycle phase#GO:0022403;negative regulation of cellular process#GO:0048523;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;mitotic cell cycle checkpoint#GO:0007093;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;mitotic DNA integrity checkpoint#GO:0044774;meiotic chromosome segregation#GO:0045132;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;reproduction#GO:0000003;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;homologous recombination#GO:0035825;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 HUMAN|HGNC=20686|UniProtKB=Q8IV76 Q8IV76 PASD1 PTHR46055:SF4 CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT CIRCADIAN CLOCK PROTEIN PASD1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;circadian regulation of gene expression#GO:0032922;multicellular organismal process#GO:0032501;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4270|UniProtKB=P09681 P09681 GIP PTHR15211:SF0 GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE GASTRIC INHIBITORY POLYPEPTIDE protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to nutrient levels#GO:0031667;response to stress#GO:0006950;response to extracellular stimulus#GO:0009991;response to starvation#GO:0042594 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=9999|UniProtKB=P49796 P49796 RGS3 PTHR46848:SF1 REGULATOR OF G-PROTEIN SIGNALING 3 REGULATOR OF G-PROTEIN SIGNALING 3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=48|UniProtKB=O75027 O75027 ABCB7 PTHR24221:SF402 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 7, MITOCHONDRIAL pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=21359|UniProtKB=Q8TB92 Q8TB92 HMGCLL1 PTHR42738:SF5 HYDROXYMETHYLGLUTARYL-COA LYASE 3-HYDROXY-3-METHYLGLUTARYL-COA LYASE, CYTOPLASMIC lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;fatty acid derivative metabolic process#GO:1901568;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 lyase#PC00144 HUMAN|HGNC=24967|UniProtKB=Q9H081 Q9H081 MIS12 PTHR14527:SF2 PROTEIN MIS12 HOMOLOG PROTEIN MIS12 HOMOLOG cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;kinetochore organization#GO:0051383;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;nuclear division#GO:0000280;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein-DNA complex assembly#GO:0065004;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;protein localization to kinetochore#GO:0034501;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;protein localization to organelle#GO:0033365;kinetochore assembly#GO:0051382;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;organelle assembly#GO:0070925;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;organelle fission#GO:0048285 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;condensed nuclear chromosome kinetochore#GO:0000778;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 HUMAN|HGNC=7565|UniProtKB=P13349 P13349 MYF5 PTHR11534:SF3 MYOGENIC FACTOR MYOGENIC FACTOR 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;regulation of cell differentiation#GO:0045595;nucleobase-containing compound metabolic process#GO:0006139;muscle structure development#GO:0061061;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of cell differentiation#GO:0045597;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of developmental process#GO:0051094;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=28505|UniProtKB=Q8IYS8 Q8IYS8 BOD1L2 PTHR31532:SF10 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 FAMILY MEMBER BIORIENTATION OF CHROMOSOMES IN CELL DIVISION PROTEIN 1-RELATED HUMAN|HGNC=4867|UniProtKB=Q15751 Q15751 HERC1 PTHR22870:SF346 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC1-RELATED guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=30037|UniProtKB=Q96JA3 Q96JA3 PLEKHA8 PTHR10219:SF90 GLYCOLIPID TRANSFER PROTEIN-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8 binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 transfer/carrier protein#PC00219 HUMAN|HGNC=30532|UniProtKB=Q9BT25 Q9BT25 HAUS8 PTHR31807:SF2 AUGMIN FAMILY MEMBER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 8 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 HUMAN|HGNC=18305|UniProtKB=O75787 O75787 ATP6AP2 PTHR13351:SF5 RENIN RECEPTOR RENIN RECEPTOR cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of Wnt signaling pathway#GO:0030177;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;signaling#GO:0023052;positive regulation of biological process#GO:0048518;Wnt signaling pathway#GO:0016055 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=1309|UniProtKB=Q8WUA7 Q8WUA7 TBC1D22A PTHR22957:SF255 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 22A GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=24098|UniProtKB=O94875 O94875 SORBS2 PTHR14167:SF56 SH3 DOMAIN-CONTAINING SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=30047|UniProtKB=P0CW19 P0CW19 LIMS3 PTHR24210:SF11 LIM DOMAIN-CONTAINING PROTEIN LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 1-RELATED regulation of cell morphogenesis involved in differentiation#GO:0010769;signal transduction#GO:0007165;positive regulation of cell-substrate adhesion#GO:0010811;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of signal transduction#GO:0009967;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;substrate adhesion-dependent cell spreading#GO:0034446;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;integrin-mediated signaling pathway#GO:0007229;regulation of cell adhesion#GO:0030155;positive regulation of cell development#GO:0010720;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;cellular developmental process#GO:0048869;cell-cell junction organization#GO:0045216;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of cell differentiation#GO:0045597;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;cell junction organization#GO:0034330;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cell adhesion#GO:0045785 cytoplasm#GO:0005737;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 HUMAN|HGNC=24127|UniProtKB=Q9BX73 Q9BX73 TM2D2 PTHR21016:SF4 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=251|UniProtKB=P00326 P00326 ADH1C PTHR43880:SF57 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE 1C cation binding#GO:0043169;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 response to organic substance#GO:0010033;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=26538|UniProtKB=Q5TIE3 Q5TIE3 VWA5B1 PTHR46299:SF1 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2-RELATED VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B1 HUMAN|HGNC=3499|UniProtKB=P22794 P22794 EVI2A PTHR15568:SF0 ECOTROPIC VIRAL INTEGRATION SITE 2A PROTEIN EVI2A transmembrane signal receptor#PC00197 HUMAN|HGNC=25895|UniProtKB=Q53GL7 Q53GL7 PARP10 PTHR14453:SF94 PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP10 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription corepressor activity#GO:0003714 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;gene expression#GO:0010467;negative regulation of metabolic process#GO:0009892;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28171|UniProtKB=Q9BSH5 Q9BSH5 HDHD3 PTHR46191:SF2 FAMILY NOT NAMED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=18468|UniProtKB=Q9NQE9 Q9NQE9 HINT3 PTHR12486:SF5 APRATAXIN-RELATED HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 3 damaged DNA-binding protein#PC00086 HUMAN|HGNC=16490|UniProtKB=Q6V1X1 Q6V1X1 DPP8 PTHR11731:SF98 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 8 serine protease#PC00203 HUMAN|HGNC=435|UniProtKB=P09917 P09917 ALOX5 PTHR11771:SF5 LIPOXYGENASE POLYUNSATURATED FATTY ACID 5-LIPOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 long-chain fatty acid metabolic process#GO:0001676;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;oxidation-reduction process#GO:0055114;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 oxygenase#PC00177 HUMAN|HGNC=11034|UniProtKB=Q2Y0W8 Q2Y0W8 SLC4A8 PTHR11453:SF37 ANION EXCHANGE PROTEIN ELECTRONEUTRAL SODIUM BICARBONATE EXCHANGER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=17565|UniProtKB=Q8N4C8 Q8N4C8 MINK1 PTHR48015:SF11 SERINE/THREONINE-PROTEIN KINASE TAO MISSHAPEN-LIKE KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;actin cytoskeleton reorganization#GO:0031532;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;actin cytoskeleton organization#GO:0030036;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=13194|UniProtKB=O43264 O43264 ZW10 PTHR12205:SF0 CENTROMERE/KINETOCHORE PROTEIN ZW10 CENTROMERE/KINETOCHORE PROTEIN ZW10 HOMOLOG endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;negative regulation of sister chromatid segregation#GO:0033046;cellular localization#GO:0051641;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;regulation of mitotic sister chromatid segregation#GO:0033047;negative regulation of cellular component organization#GO:0051129;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;intracellular transport#GO:0046907;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;mitotic cell cycle phase transition#GO:0044772;regulation of chromosome separation#GO:1905818;transport#GO:0006810;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;negative regulation of organelle organization#GO:0010639;mitotic spindle assembly checkpoint#GO:0007094;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;mitotic cell cycle checkpoint#GO:0007093;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;metaphase/anaphase transition of cell cycle#GO:0044784;negative regulation of chromosome separation#GO:1905819;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular#GO:0005622;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=5188|UniProtKB=Q9NR22 Q9NR22 PRMT8 PTHR11006:SF47 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 8 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=31658|UniProtKB=A0PK05 A0PK05 TMEM72 PTHR28474:SF1 TRANSMEMBRANE PROTEIN 72 TRANSMEMBRANE PROTEIN 72 HUMAN|HGNC=20161|UniProtKB=O94842 O94842 TOX4 PTHR45781:SF2 AGAP000281-PA TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 4 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;chromatin DNA binding#GO:0031490;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=7371|UniProtKB=Q13421 Q13421 MSLN PTHR23412:SF6 STEREOCILIN RELATED MESOTHELIN cell adhesion#GO:0007155;cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;biological adhesion#GO:0022610 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 cell adhesion molecule#PC00069 HUMAN|HGNC=9777|UniProtKB=P20336 P20336 RAB3A PTHR47980:SF9 LD44762P RAS-RELATED PROTEIN RAB-3A cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;protein secretion#GO:0009306;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of neurotransmitter secretion#GO:0046928;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;anterograde trans-synaptic signaling#GO:0098916;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of secretion#GO:0051046;secretion#GO:0046903;synaptic signaling#GO:0099536;axonogenesis#GO:0007409;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;cellular developmental process#GO:0048869;neurotransmitter secretion#GO:0007269;regulation of organelle organization#GO:0033043;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;synapse organization#GO:0050808;establishment of protein localization to extracellular region#GO:0035592;axon development#GO:0061564;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of neurotransmitter levels#GO:0001505;modulation of chemical synaptic transmission#GO:0050804;protein transport#GO:0015031;neuron development#GO:0048666;regulation of trans-synaptic signaling#GO:0099177;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;vesicle fusion#GO:0006906;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;developmental process#GO:0032502;transport#GO:0006810;regulation of signaling#GO:0023051;cell projection morphogenesis#GO:0048858;peptide secretion#GO:0002790;amide transport#GO:0042886;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;regulation of transport#GO:0051049;neurotransmitter transport#GO:0006836;signal release#GO:0023061;neuron differentiation#GO:0030182;vesicle organization#GO:0016050;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;cell-cell signaling#GO:0007267;synaptic vesicle exocytosis#GO:0016079;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;protein localization to plasma membrane#GO:0072659;regulation of cell communication#GO:0010646;cell morphogenesis involved in differentiation#GO:0000904;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;protein localization to cell periphery#GO:1990778;localization#GO:0051179;signal release from synapse#GO:0099643;membrane fusion#GO:0061025;cell morphogenesis involved in neuron differentiation#GO:0048667;organelle organization#GO:0006996;cell junction organization#GO:0034330;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;generation of neurons#GO:0048699;vesicle-mediated transport in synapse#GO:0099003 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;anchored component of membrane#GO:0031225;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 Synaptic vesicle trafficking#P05734>Rab3A#P05780 HUMAN|HGNC=25872|UniProtKB=Q9H7X3 Q9H7X3 ZNF696 PTHR24379:SF77 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 696 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=105|UniProtKB=Q6P4Q7 Q6P4Q7 CNNM4 PTHR12064:SF26 ANCIENT CONSERVED DOMAIN PROTEIN-RELATED METAL TRANSPORTER CNNM4 inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;divalent inorganic cation homeostasis#GO:0072507;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cation transport#GO:0006812;chemical homeostasis#GO:0048878;localization#GO:0051179;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;divalent inorganic cation transport#GO:0072511;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=24590|UniProtKB=Q9C005 Q9C005 DPY30 PTHR23356:SF16 DPY30-RELATED PROTEIN DPY-30 HOMOLOG negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;histone methylation#GO:0016571;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein alkylation#GO:0008213;protein methylation#GO:0006479;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;histone H3-K4 methylation#GO:0051568;cellular protein metabolic process#GO:0044267;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;chromatin silencing at telomere#GO:0006348;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;histone lysine methylation#GO:0034968;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=16937|UniProtKB=O75915 O75915 ARL6IP5 PTHR12859:SF2 PRA1 PROTEIN PRA1 FAMILY PROTEIN 3 localization#GO:0051179;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of biological quality#GO:0065008;regulation of neurotransmitter levels#GO:0001505;neurotransmitter transport#GO:0006836;transport#GO:0006810;biological regulation#GO:0065007;regulation of localization#GO:0032879;negative regulation of transport#GO:0051051 cellular anatomical entity#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046 HUMAN|HGNC=26255|UniProtKB=Q5BVD1 Q5BVD1 TTMP PTHR14636:SF1 TPA-INDUCED TRANSMEMBRANE PROTEIN TPA-INDUCED TRANSMEMBRANE PROTEIN HUMAN|HGNC=12235|UniProtKB=A0A0A6YYK4 A0A0A6YYK4 TRBV7-1 PTHR23268:SF108 T-CELL RECEPTOR BETA CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=17085|UniProtKB=Q9Y2D4 Q9Y2D4 EXOC6B PTHR12702:SF3 SEC15 EXOCYST COMPLEX COMPONENT 6B vesicle fusion#GO:0006906;vesicle-mediated transport to the plasma membrane#GO:0098876;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;exocytic process#GO:0140029;Golgi to plasma membrane transport#GO:0006893;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;vesicle organization#GO:0016050;export from cell#GO:0140352;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=17217|UniProtKB=Q14689 Q14689 DIP2A PTHR22754:SF34 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 HOMOLOG A cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|HGNC=17162|UniProtKB=Q9Y4Y9 Q9Y4Y9 LSM5 PTHR20971:SF0 U6 SNRNA-ASSOCIATED PROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=17313|UniProtKB=Q9UHH9 Q9UHH9 IP6K2 PTHR12400:SF47 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;organic hydroxy compound biosynthetic process#GO:1901617;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 HUMAN|HGNC=37245|UniProtKB=P0C6A0 P0C6A0 ZGLP1 PTHR47341:SF1 GATA-TYPE ZINC FINGER PROTEIN 1 GATA-TYPE ZINC FINGER PROTEIN 1 negative regulation of gene expression#GO:0010629;male gamete generation#GO:0048232;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;spermatogenesis#GO:0007283;reproductive process#GO:0022414;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;developmental process involved in reproduction#GO:0003006;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;cellular process involved in reproduction in multicellular organism#GO:0022412;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;multi-organism process#GO:0051704;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=21374|UniProtKB=Q96EU6 Q96EU6 RRP36 PTHR21738:SF0 UNCHARACTERIZED RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 HUMAN|HGNC=18131|UniProtKB=Q71H61 Q71H61 ILDR2 PTHR15923:SF0 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING RECEPTOR 2 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=14001|UniProtKB=Q9GZV8 Q9GZV8 PRDM14 PTHR16515:SF19 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 14 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;histone methylation#GO:0016571;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;protein alkylation#GO:0008213;protein methylation#GO:0006479;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;macromolecule methylation#GO:0043414;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;peptidyl-arginine methylation#GO:0018216;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=16234|UniProtKB=Q8NI51 Q8NI51 CTCFL PTHR24406:SF11 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED TRANSCRIPTIONAL REPRESSOR CTCFL heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosome#GO:0005694;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28150|UniProtKB=Q6UXH1 Q6UXH1 CRELD2 PTHR24034:SF110 EGF-LIKE DOMAIN-CONTAINING PROTEIN PROTEIN DISULFIDE ISOMERASE CRELD2 extracellular matrix structural protein#PC00103 HUMAN|HGNC=15852|UniProtKB=Q8N6T3 Q8N6T3 ARFGAP1 PTHR46395:SF1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 signal transduction#GO:0007165;membrane organization#GO:0061024;transport#GO:0006810;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of intracellular signal transduction#GO:1902531;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;membrane invagination#GO:0010324;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;vesicle organization#GO:0016050;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of endocytosis#GO:0030100;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;localization#GO:0051179;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of Ras protein signal transduction#GO:0046578 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 Integrin signalling pathway#P00034>ASAP1#P00909 HUMAN|HGNC=16996|UniProtKB=Q15363 Q15363 TMED2 PTHR22811:SF177 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=25401|UniProtKB=Q8TCP9 Q8TCP9 FAM200A PTHR45935:SF1 PROTEIN ZBED8-RELATED PROTEIN FAM200A HUMAN|HGNC=25782|UniProtKB=Q9BTE3 Q9BTE3 MCMBP PTHR13489:SF0 UNCHARACTERIZED MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN binding#GO:0005488;chromatin binding#GO:0003682 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;DNA biosynthetic process#GO:0071897;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=20575|UniProtKB=Q5TCH4 Q5TCH4 CYP4A22 PTHR24291:SF39 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4A11-RELATED oxygenase#PC00177 HUMAN|HGNC=6340|UniProtKB=Q14943 Q14943 KIR3DS1 PTHR11738:SF166 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 3DL1-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=15465|UniProtKB=Q9NQX3 Q9NQX3 GPHN PTHR10192:SF5 MOLYBDOPTERIN BIOSYNTHESIS PROTEIN GEPHYRIN adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=1268|UniProtKB=Q8WU66 Q8WU66 TSPEAR PTHR15261:SF4 THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING PROTEIN regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intercellular signal molecule#PC00207 HUMAN|HGNC=2457|UniProtKB=P68400 P68400 CSNK2A1 PTHR24054:SF16 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA-RELATED transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;peptidyl-threonine phosphorylation#GO:0018107;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;cell cycle#GO:0007049;peptidyl-serine modification#GO:0018209;regulation of cell cycle#GO:0051726;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Cadherin signaling pathway#P00012>Casein kinase II#P00462;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Parkinson disease#P00049>Casein kinase II#P01236 HUMAN|HGNC=16753|UniProtKB=P30041 P30041 PRDX6 PTHR43503:SF11 MCG48959-RELATED PEROXIREDOXIN-6 biological regulation#GO:0065007;regulation of biological process#GO:0050789;homeostatic process#GO:0042592;cellular process#GO:0009987;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 peroxidase#PC00180 HUMAN|HGNC=24677|UniProtKB=Q86TG1 Q86TG1 TMEM150A PTHR21324:SF6 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED TRANSMEMBRANE PROTEIN 150A process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;regulation of catabolic process#GO:0009894;regulation of cellular process#GO:0050794;regulation of autophagy#GO:0010506;biological regulation#GO:0065007;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;cellular catabolic process#GO:0044248;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=319|UniProtKB=P16112 P16112 ACAN PTHR22804:SF42 AGGRECAN/VERSICAN PROTEOGLYCAN AGGRECAN CORE PROTEIN extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=23376|UniProtKB=Q5SR56 Q5SR56 MFSD14B PTHR23504:SF32 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 HIPPOCAMPUS ABUNDANT TRANSCRIPT-LIKE PROTEIN 1-RELATED HUMAN|HGNC=30725|UniProtKB=Q9UKR8 Q9UKR8 TSPAN16 PTHR19282:SF455 TETRASPANIN TETRASPANIN-16 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=24023|UniProtKB=Q6TDP4 Q6TDP4 KLHL17 PTHR24412:SF454 KELCH PROTEIN KELCH-LIKE PROTEIN 17 scaffold/adaptor protein#PC00226 HUMAN|HGNC=330|UniProtKB=O00253 O00253 AGRP PTHR16551:SF4 AGOUTI RELATED AGOUTI-RELATED PROTEIN neuropeptide hormone activity#GO:0005184;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;behavior#GO:0007610;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;positive regulation of biological process#GO:0048518 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=26016|UniProtKB=Q9H400 Q9H400 LIME1 PTHR47740:SF1 LCK-INTERACTING TRANSMEMBRANE ADAPTER 1, LIME1 LCK-INTERACTING TRANSMEMBRANE ADAPTER 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6713|UniProtKB=Q15722 Q15722 LTB4R PTHR24230:SF51 G-PROTEIN COUPLED RECEPTOR LEUKOTRIENE B4 RECEPTOR 1 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=25142|UniProtKB=Q86VG3 Q86VG3 IFTAP PTHR35543:SF1 PROTEIN C11ORF74 INTRAFLAGELLAR TRANSPORT-ASSOCIATED PROTEIN protein-containing complex binding#GO:0044877;binding#GO:0005488 male gamete generation#GO:0048232;fertilization#GO:0009566;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;developmental process#GO:0032502;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;reproduction#GO:0000003;spermatogenesis#GO:0007283;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;acrosome reaction#GO:0007340;multicellular organismal reproductive process#GO:0048609 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=30557|UniProtKB=Q8WUT9 Q8WUT9 SLC25A43 PTHR24089:SF246 SOLUTE CARRIER FAMILY 25 SOLUTE CARRIER FAMILY 25 MEMBER 43 mitochondrial carrier protein#PC00158 HUMAN|HGNC=14623|UniProtKB=Q69YH5 Q69YH5 CDCA2 PTHR21603:SF16 ANTIGEN KI-67-LIKE PROTEIN CELL DIVISION CYCLE-ASSOCIATED PROTEIN 2 HUMAN|HGNC=8927|UniProtKB=Q93100 Q93100 PHKB PTHR10749:SF8 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 HUMAN|HGNC=19139|UniProtKB=Q8WZA1 Q8WZA1 POMGNT1 PTHR46396:SF1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=18797|UniProtKB=Q8NCW0 Q8NCW0 KREMEN2 PTHR24269:SF15 KREMEN PROTEIN KREMEN PROTEIN 2 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Kremen#P01463 HUMAN|HGNC=12035|UniProtKB=O00463 O00463 TRAF5 PTHR10131:SF83 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 5 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625;tumor necrosis factor receptor binding#GO:0005164;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of MAPK cascade#GO:0043408;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;positive regulation of protein modification process#GO:0031401;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;stress-activated MAPK cascade#GO:0051403;cellular protein metabolic process#GO:0044267;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of DNA-binding transcription factor activity#GO:0051091;positive regulation of protein metabolic process#GO:0051247;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;transcription, DNA-templated#GO:0006351;regulation of JNK cascade#GO:0046328;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;JNK cascade#GO:0007254;positive regulation of signaling#GO:0023056;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;tumor necrosis factor-mediated signaling pathway#GO:0033209;RNA biosynthetic process#GO:0032774;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of stress-activated MAPK cascade#GO:0032874;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of stress-activated protein kinase signaling cascade#GO:0070302;cellular macromolecule biosynthetic process#GO:0034645;regulation of DNA-binding transcription factor activity#GO:0051090;cellular response to chemical stimulus#GO:0070887;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of stress-activated MAPK cascade#GO:0032872;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cellular macromolecule biosynthetic process#GO:2000112;protein K63-linked ubiquitination#GO:0070534 membrane protein complex#GO:0098796;receptor complex#GO:0043235;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=16626|UniProtKB=Q8WZA2 Q8WZA2 RAPGEF4 PTHR23113:SF175 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=581|UniProtKB=O00213 O00213 APBB1 PTHR14058:SF5 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1 amyloid-beta binding#GO:0001540;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Alzheimer disease-amyloid secretase pathway#P00003>Fe65#P00087;Alzheimer disease-presenilin pathway#P00004>Fe65#P00126 HUMAN|HGNC=26913|UniProtKB=Q8NBT2 Q8NBT2 SPC24 PTHR22142:SF2 UNCHARACTERIZED KINETOCHORE PROTEIN SPC24 HUMAN|HGNC=31894|UniProtKB=Q5H9E4 Q5H9E4 SLC25A53 PTHR46131:SF5 SD08549P SOLUTE CARRIER FAMILY 25 MEMBER 53 HUMAN|HGNC=10411|UniProtKB=P62847 P62847 RPS24 PTHR10496:SF7 40S RIBOSOMAL PROTEIN S24 40S RIBOSOMAL PROTEIN S24 ribosomal protein#PC00202 HUMAN|HGNC=7594|UniProtKB=Q9UKN7 Q9UKN7 MYO15A PTHR13140:SF709 MYOSIN UNCONVENTIONAL MYOSIN-XV pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=10767|UniProtKB=Q12874 Q12874 SF3A3 PTHR12786:SF3 SPLICING FACTOR SF3A-RELATED SPLICING FACTOR 3A SUBUNIT 3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=12966|UniProtKB=Q13360 Q13360 ZNF177 PTHR24381:SF346 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 177-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13702|UniProtKB=Q96CA5 Q96CA5 BIRC7 PTHR10044:SF163 INHIBITOR OF APOPTOSIS BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 7 cysteine-type peptidase activity#GO:0008234;peptidase inhibitor activity#GO:0030414;ubiquitin-protein transferase activity#GO:0004842;protease binding#GO:0002020;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;transferase activity#GO:0016740;cysteine-type endopeptidase activity#GO:0004197;ubiquitin protein ligase activity#GO:0061630;hydrolase activity#GO:0016787;ubiquitin-like protein ligase activity#GO:0061659;cysteine-type endopeptidase inhibitor activity#GO:0004869;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;regulation of hydrolase activity#GO:0051336;spindle organization#GO:0007051;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;negative regulation of endopeptidase activity#GO:0010951;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;programmed cell death#GO:0012501;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043154;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;mitotic spindle organization#GO:0007052;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;protein processing#GO:0016485;positive regulation of metabolic process#GO:0009893;negative regulation of programmed cell death#GO:0043069;mitotic spindle assembly#GO:0090307;cell death#GO:0008219;mitotic nuclear division#GO:0140014;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;negative regulation of peptidase activity#GO:0010466;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;microtubule-based process#GO:0007017;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell cycle#GO:0007049;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 protease inhibitor#PC00191 HUMAN|HGNC=14267|UniProtKB=O14917 O14917 PCDH17 PTHR24028:SF41 CADHERIN-87A PROTOCADHERIN-17 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 HUMAN|HGNC=12458|UniProtKB=P62987 P62987 UBA52 PTHR10666:SF260 UBIQUITIN UBIQUITIN-60S RIBOSOMAL PROTEIN L40 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14774|UniProtKB=Q8NHB8 Q8NHB8 OR5K2 PTHR26452:SF38 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5K2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=21915|UniProtKB=Q9BSE4 Q9BSE4 HERPUD2 PTHR12943:SF5 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UBIQUITIN-LIKE DOMAIN MEMBER 2 PROTEIN response to organic substance#GO:0010033;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to unfolded protein#GO:0006986;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;cellular response to stress#GO:0033554;signaling#GO:0023052 HUMAN|HGNC=17443|UniProtKB=Q969Z0 Q969Z0 TBRG4 PTHR21228:SF59 FAST LEU-RICH DOMAIN-CONTAINING FAST KINASE DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=8809|UniProtKB=Q15118 Q15118 PDK1 PTHR11947:SF14 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 1, MITOCHONDRIAL transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;negative regulation of metabolic process#GO:0009892;regulation of catalytic activity#GO:0050790;chemical homeostasis#GO:0048878;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=29|UniProtKB=O95477 O95477 ABCA1 PTHR19229:SF34 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA PHOSPHOLIPID-TRANSPORTING ATPASE ABCA1 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;ATPase-coupled intramembrane lipid transporter activity#GO:0140326;catalytic activity#GO:0003824;phosphatidylcholine transporter activity#GO:0008525;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;phospholipid transporter activity#GO:0005548;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;lipid localization#GO:0010876;phospholipid transport#GO:0015914;lipid transport#GO:0006869 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=6547|UniProtKB=P01130 P01130 LDLR PTHR24270:SF21 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR apolipoprotein#PC00052 HUMAN|HGNC=11816|UniProtKB=Q9Y5L4 Q9Y5L4 TIMM13 PTHR19338:SF0 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 13 HOMOLOG MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM13 cellular localization#GO:0051641;protein insertion into mitochondrial inner membrane#GO:0045039;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;inner mitochondrial membrane organization#GO:0007007;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;mitochondrial membrane organization#GO:0007006 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;intracellular organelle lumen#GO:0070013;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758 HUMAN|HGNC=26212|UniProtKB=P61009 P61009 SPCS3 PTHR12804:SF0 MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23 SIGNAL PEPTIDASE COMPLEX SUBUNIT 3 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;establishment of protein localization#GO:0045184;protein processing#GO:0016485;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein localization to endoplasmic reticulum#GO:0070972;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;signal peptide processing#GO:0006465;cellular amide metabolic process#GO:0043603 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 HUMAN|HGNC=4248|UniProtKB=Q92820 Q92820 GGH PTHR11315:SF0 PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE GAMMA-GLUTAMYL HYDROLASE cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;pteridine-containing compound metabolic process#GO:0042558;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;folic acid-containing compound metabolic process#GO:0006760;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=14773|UniProtKB=P0DN80 P0DN80 OR5H8 PTHR26452:SF775 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5H8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=14351|UniProtKB=Q9UHP7 Q9UHP7 CLEC2D PTHR45710:SF23 C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER D external side of plasma membrane#GO:0009897;leaflet of membrane bilayer#GO:0097478;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=554|UniProtKB=Q10567 Q10567 AP1B1 PTHR11134:SF31 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-1 COMPLEX SUBUNIT BETA-1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane traffic protein#PC00150 HUMAN|HGNC=9588|UniProtKB=P60484 P60484 PTEN PTHR12305:SF81 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 p53 pathway#P00059>PTEN#G01579;p53 pathway feedback loops 2#P04398>PTEN#G04714;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PTEN#P00849;p53 pathway#P00059>PTEN#P01480;PI3 kinase pathway#P00048>PTEN#P01189;Hypoxia response via HIF activation#P00030>PTEN#P00824;CCKR signaling map#P06959>PTEN#P07071;p53 pathway feedback loops 2#P04398>PTEN#P04658 HUMAN|HGNC=30135|UniProtKB=Q7Z4N8 Q7Z4N8 P4HA3 PTHR10869:SF207 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-3-RELATED protein modifying enzyme#PC00260 HUMAN|HGNC=29362|UniProtKB=Q9C0D7 Q9C0D7 ZC3H12C PTHR12876:SF36 N4BP1-RELATED RIBONUCLEASE ZC3H12C-RELATED catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 endoribonuclease#PC00094 HUMAN|HGNC=26823|UniProtKB=Q6P6B1 Q6P6B1 ERICH5 PTHR23006:SF0 UNCHARACTERIZED GLUTAMATE-RICH PROTEIN 5 HUMAN|HGNC=13266|UniProtKB=Q9GZR7 Q9GZR7 DDX24 PTHR24031:SF91 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX24 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9655|UniProtKB=P26045 P26045 PTPN3 PTHR45706:SF5 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 protein phosphatase#PC00195 HUMAN|HGNC=5102|UniProtKB=P31271 P31271 HOXA13 PTHR45804:SF3 SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN HOMEOBOX PROTEIN HOX-A13 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=25761|UniProtKB=Q96BJ3 Q96BJ3 AIDA PTHR28654:SF1 AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN lipid binding#GO:0008289;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;phospholipid binding#GO:0005543;binding#GO:0005488 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=2264|UniProtKB=Q14061 Q14061 COX17 PTHR16719:SF0 CYTOCHROME C OXIDASE COPPER CHAPERONE CYTOCHROME C OXIDASE COPPER CHAPERONE copper ion binding#GO:0005507;cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914 chaperone#PC00072 HUMAN|HGNC=4722|UniProtKB=Q92522 Q92522 H1-10 PTHR11467:SF21 HISTONE H1 HISTONE H1.10 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of chromatin silencing#GO:0031935;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of chromatin silencing#GO:0031936;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of chromatin organization#GO:1902275;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;chromosome condensation#GO:0030261;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;positive regulation of macromolecule biosynthetic process#GO:0010557;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of DNA recombination#GO:0000018;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone#PC00118 HUMAN|HGNC=19854|UniProtKB=Q96MY7 Q96MY7 FAM161B PTHR21501:SF4 UNCHARACTERIZED PROTEIN FAM161B cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;organelle#GO:0043226;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=20764|UniProtKB=Q96S99 Q96S99 PLEKHF1 PTHR46280:SF2 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 1 lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 HUMAN|HGNC=27786|UniProtKB=Q3B7I2 Q3B7I2 CNPY1 PTHR13341:SF4 MIR-INTERACTING SAPOSIN-LIKE PROTEIN PROTEIN CANOPY HOMOLOG 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=18505|UniProtKB=Q68DV7 Q68DV7 RNF43 PTHR16200:SF2 RING ZINC FINGER E3 UBIQUITIN-PROTEIN LIGASE RNF43 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=31729|UniProtKB=Q0P6D2 Q0P6D2 DIPK1C PTHR21093:SF2 UNCHARACTERIZED DIVERGENT PROTEIN KINASE DOMAIN 1C HUMAN|HGNC=8949|UniProtKB=P36952 P36952 SERPINB5 PTHR11461:SF55 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B5 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 p53 pathway#P00059>Maspin#G01569 HUMAN|HGNC=24643|UniProtKB=P58062 P58062 SPINK7 PTHR47499:SF1 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 protease inhibitor#PC00191 HUMAN|HGNC=29239|UniProtKB=Q9ULD6 Q9ULD6 INTU PTHR21082:SF4 PROTEIN INTURNED PROTEIN INTURNED HUMAN|Gene=SELO|UniProtKB=Q9BVL4 Q9BVL4 SELENOO PTHR12153:SF15 SELENOPROTEIN O PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL HUMAN|HGNC=33754|UniProtKB=Q6PH81 Q6PH81 C16orf87 PTHR31101:SF3 UPF0547 PROTEIN C16ORF87 UPF0547 PROTEIN C16ORF87 HUMAN|HGNC=28091|UniProtKB=Q52LC2 Q52LC2 ATP6AP1L PTHR12471:SF3 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1-LIKE PROTEIN inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;proton-transporting two-sector ATPase complex#GO:0016469;plasma membrane#GO:0005886 ATP synthase#PC00002 HUMAN|HGNC=13724|UniProtKB=P61421 P61421 ATP6V0D1 PTHR11028:SF3 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 pH reduction#GO:0045851;regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;vacuolar transport#GO:0007034;transport#GO:0006810;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;biological regulation#GO:0065007;intracellular pH reduction#GO:0051452;regulation of cellular pH#GO:0030641;vacuolar acidification#GO:0007035 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;plasma membrane protein complex#GO:0098797;vacuolar membrane#GO:0005774;early endosome#GO:0005769;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ATP synthase#PC00002 HUMAN|HGNC=4533|UniProtKB=Q96P67 Q96P67 GPR82 PTHR47392:SF1 G-PROTEIN COUPLED RECEPTOR 82-RELATED G-PROTEIN COUPLED RECEPTOR 82-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=33145|UniProtKB=Q6VEQ5 Q6VEQ5 WASH2P PTHR23331:SF2 CXYORF1 WAS PROTEIN FAMILY HOMOLOG 2-RELATED HUMAN|HGNC=18182|UniProtKB=Q9ULQ1 Q9ULQ1 TPCN1 PTHR46474:SF1 TWO PORE CALCIUM CHANNEL PROTEIN 1 TWO PORE CALCIUM CHANNEL PROTEIN 1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ion channel#PC00133 CCKR signaling map#P06959>TPC1/2#P07209 HUMAN|HGNC=11207|UniProtKB=Q02086 Q02086 SP2 PTHR23235:SF1 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=8703|UniProtKB=Q9Y5G8 Q9Y5G8 PCDHGA5 PTHR24028:SF105 CADHERIN-87A PROTOCADHERIN GAMMA-A5 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=10999|UniProtKB=Q9Y2P5 Q9Y2P5 SLC27A5 PTHR43107:SF4 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN BILE ACYL-COA SYNTHETASE ligase activity#GO:0016874;transporter activity#GO:0005215;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;lipid transporter activity#GO:0005319 secondary carrier transporter#PC00258 HUMAN|HGNC=26541|UniProtKB=Q8IYT1 Q8IYT1 FAM71A PTHR22574:SF15 UNCHARACTERIZED PROTEIN FAM71A membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=23166|UniProtKB=Q8TCS8 Q8TCS8 PNPT1 PTHR11252:SF9 POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity#GO:0016740;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;nucleotidyltransferase activity#GO:0016779;ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;mitochondrial gene expression#GO:0140053;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;mitochondrial RNA metabolic process#GO:0000959;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 HUMAN|HGNC=12370|UniProtKB=Q9BYV8 Q9BYV8 CEP41 PTHR44390:SF1 CENTROSOMAL PROTEIN OF 41 KDA CENTROSOMAL PROTEIN OF 41 KDA HUMAN|HGNC=4243|UniProtKB=P56159 P56159 GFRA1 PTHR10269:SF3 GDNF RECEPTOR ALPHA GDNF FAMILY RECEPTOR ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=8654|UniProtKB=P05166 P05166 PCCB PTHR43842:SF2 PROPIONYL-COA CARBOXYLASE BETA CHAIN PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 HUMAN|HGNC=14011|UniProtKB=O95347 O95347 SMC2 PTHR43941:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2 HUMAN|HGNC=10434|UniProtKB=O75582 O75582 RPS6KA5 PTHR24351:SF115 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-5 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 p38 MAPK pathway#P05918>MSK1#P06040;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 HUMAN|HGNC=49233|UniProtKB=A8MZH6 A8MZH6 OOSP1 PTHR14380:SF3 PLACENTA-SPECIFIC PROTEIN 1 OOCYTE-SECRETED PROTEIN 1 HOMOLOG-RELATED HUMAN|HGNC=32349|UniProtKB=Q6P7N7 Q6P7N7 TMEM81 PTHR35670:SF1 TRANSMEMBRANE PROTEIN 81 TRANSMEMBRANE PROTEIN 81 HUMAN|HGNC=12649|UniProtKB=O95292 O95292 VAPB PTHR10809:SF12 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN B/C protein binding#GO:0005515;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular localization#GO:0051641;organelle localization#GO:0051640;endoplasmic reticulum organization#GO:0007029;membrane organization#GO:0061024;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=11099|UniProtKB=Q14527 Q14527 HLTF PTHR45626:SF39 TRANSCRIPTION TERMINATION FACTOR 2-RELATED HELICASE-LIKE TRANSCRIPTION FACTOR Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=25382|UniProtKB=Q9H061 Q9H061 TMEM126A PTHR16296:SF4 UNCHARACTERIZED HYPOTHALAMUS PROTEIN HT007 TRANSMEMBRANE PROTEIN 126A cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=24852|UniProtKB=Q9P107 Q9P107 GMIP PTHR15228:SF16 SPERMATHECAL PHYSIOLOGY VARIANT GEM-INTERACTING PROTEIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;negative regulation of catalytic activity#GO:0043086;positive regulation of hydrolase activity#GO:0051345;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=15942|UniProtKB=Q9P2W9 Q9P2W9 STX18 PTHR15959:SF1 SYNTAXIN-18 SYNTAXIN-18 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 SNARE protein#PC00034 HUMAN|HGNC=25504|UniProtKB=Q96A72 Q96A72 MAGOHB PTHR12638:SF1 PROTEIN MAGO NASHI HOMOLOG PROTEIN MAGO NASHI HOMOLOG 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;exon-exon junction complex#GO:0035145;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=3722|UniProtKB=O75344 O75344 FKBP6 PTHR46674:SF1 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 chaperone#PC00072 HUMAN|HGNC=1469|UniProtKB=Q8N5S9 Q8N5S9 CAMKK1 PTHR24346:SF39 MAP/MICROTUBULE AFFINITY-REGULATING KINASE CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>CaMKK#P07034 HUMAN|HGNC=17281|UniProtKB=Q9H3K2 Q9H3K2 GHITM PTHR23291:SF112 BAX INHIBITOR-RELATED GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN HUMAN|HGNC=34401|UniProtKB=A2RU48 A2RU48 SMCO3 PTHR35972:SF1 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=9370|UniProtKB=P49643 P49643 PRIM2 PTHR10537:SF3 DNA PRIMASE LARGE SUBUNIT DNA PRIMASE LARGE SUBUNIT pre-replicative complex#GO:0036387;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;replisome#GO:0030894;epsilon DNA polymerase complex#GO:0008622;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;replication fork#GO:0005657;membrane-enclosed lumen#GO:0031974;origin recognition complex#GO:0000808;organelle lumen#GO:0043233;nucleus#GO:0005634;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;DNA replication preinitiation complex#GO:0031261;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;CMG complex#GO:0071162;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;MCM core complex#GO:0097373;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 primase#PC00189 DNA replication#P00017>Primase#P00528 HUMAN|HGNC=8270|UniProtKB=Q96R27 Q96R27 OR2M4 PTHR26453:SF91 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2M4 transmembrane signal receptor#PC00197 HUMAN|HGNC=11358|UniProtKB=O75886 O75886 STAM2 PTHR45929:SF1 JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE SIGNAL TRANSDUCING ADAPTER MOLECULE 2 protein catabolic process in the vacuole#GO:0007039;endosomal transport#GO:0016197;cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to vacuole#GO:0072666;cellular response to stimulus#GO:0051716;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cell communication#GO:0007154;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;cellular protein catabolic process#GO:0044257;regulation of cellular process#GO:0050794;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28238|UniProtKB=Q969Y0 Q969Y0 NXPE3 PTHR16165:SF9 BRUSH BORDER-RELATED NXPE FAMILY MEMBER 3 HUMAN|HGNC=20693|UniProtKB=P58417 P58417 NXPH1 PTHR17103:SF13 NEUREXOPHILIN NEUREXOPHILIN-1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 HUMAN|HGNC=6147|UniProtKB=P38570 P38570 ITGAE PTHR23220:SF79 INTEGRIN ALPHA INTEGRIN ALPHA-E integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 HUMAN|HGNC=28468|UniProtKB=Q8WV41 Q8WV41 SNX33 PTHR45827:SF3 SORTING NEXIN SORTING NEXIN-33 scaffold/adaptor protein#PC00226 HUMAN|HGNC=4126|UniProtKB=Q8N4A0 Q8N4A0 GALNT4 PTHR11675:SF7 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 4 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=30649|UniProtKB=Q76M96 Q76M96 CCDC80 PTHR46792:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 80 COILED-COIL DOMAIN-CONTAINING PROTEIN 80 HUMAN|HGNC=25903|UniProtKB=Q8NBU5 Q8NBU5 ATAD1 PTHR45644:SF2 AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=24283|UniProtKB=Q4FZB7 Q4FZB7 KMT5B PTHR12977:SF12 SUPPRESSOR OF VARIEGATION 4-20-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone methylation#GO:0016571;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;histone lysine methylation#GO:0034968;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;peptidyl-lysine trimethylation#GO:0018023;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=7973|UniProtKB=Q9Y466 Q9Y466 NR2E1 PTHR24083:SF98 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP E MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=28866|UniProtKB=Q9NZI8 Q9NZI8 IGF2BP1 PTHR10288:SF92 KH DOMAIN CONTAINING RNA BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 regulation of biological process#GO:0050789;system development#GO:0048731;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;anatomical structure development#GO:0048856;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological regulation#GO:0065007;gene expression#GO:0010467;multicellular organismal process#GO:0032501;regulation of gene expression#GO:0010468;nervous system development#GO:0007399;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=24867|UniProtKB=Q9NZD2 Q9NZD2 GLTP PTHR10219:SF74 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 transfer/carrier protein#PC00219 HUMAN|HGNC=26563|UniProtKB=Q96M02 Q96M02 C10orf90 PTHR21553:SF24 ALMS1-RELATED (E2-INDEPENDENT) E3 UBIQUITIN-CONJUGATING ENZYME FATS regulation of microtubule-based process#GO:0032886;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;regulation of cell cycle process#GO:0010564;regulation of biological process#GO:0050789;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;regulation of cell cycle#GO:0051726;regulation of centrosome duplication#GO:0010824 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=9775|UniProtKB=O95755 O95755 RAB36 PTHR47977:SF10 LD21953P-RELATED RAS-RELATED PROTEIN RAB-36 HUMAN|HGNC=25077|UniProtKB=P0DPF5 P0DPF5 C2orf27A PTHR16471:SF2 CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN-LIKE PROTEIN SUBFAMILY NOT NAMED HUMAN|HGNC=28289|UniProtKB=Q96F63 Q96F63 CCDC97 PTHR31840:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 HUMAN|HGNC=20795|UniProtKB=Q8NCR9 Q8NCR9 CLRN3 PTHR31548:SF3 CLARIN CLARIN-3 HUMAN|HGNC=37156|UniProtKB=P0CJ69 P0CJ69 MTRNR2L2 PTHR33895:SF15 HUMANIN-LIKE 4 HUMANIN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor binding#GO:0005102 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;plasma membrane bounded cell projection assembly#GO:0120031;negative regulation of cellular process#GO:0048523;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=21317|UniProtKB=Q7RTS9 Q7RTS9 DYM PTHR12895:SF9 DYMECLIN DYMECLIN endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=34383|UniProtKB=A6NGG8 A6NGG8 PCARE PTHR22017:SF0 UNCHARACTERIZED PHOTORECEPTOR CILIUM ACTIN REGULATOR HUMAN|HGNC=8355|UniProtKB=Q96RD1 Q96RD1 OR6C1 PTHR26454:SF27 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=25900|UniProtKB=Q9H425 Q9H425 C1orf198 PTHR34394:SF1 SIMILAR TO RIKEN CDNA 2310022B05 DUF4706 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=15346|UniProtKB=Q8NGC1 Q8NGC1 OR11G2 PTHR24242:SF183 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11G2 G-protein coupled receptor#PC00021 HUMAN|HGNC=6371|UniProtKB=P03952 P03952 KLKB1 PTHR24253:SF64 TRANSMEMBRANE PROTEASE SERINE PLASMA KALLIKREIN serine protease#PC00203 Blood coagulation#P00011>Prekallikrein#P00439;Blood coagulation#P00011>Kallikrein#P00437 HUMAN|HGNC=8810|UniProtKB=Q15119 Q15119 PDK2 PTHR11947:SF15 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 2, MITOCHONDRIAL transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;negative regulation of metabolic process#GO:0009892;regulation of catalytic activity#GO:0050790;chemical homeostasis#GO:0048878;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 TCA cycle#P00051>Pyruvate Dehydrogenase#P01266 HUMAN|HGNC=8346|UniProtKB=A6NKK0 A6NKK0 OR5H1 PTHR26452:SF747 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5H1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=3250|UniProtKB=P47813 P47813 EIF1AX PTHR21668:SF4 EIF-1A EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, X-CHROMOSOMAL translation initiation factor#PC00224 HUMAN|HGNC=18551|UniProtKB=Q9BY27 Q9BY27 DGCR6L PTHR13054:SF6 DIGEORGE SYNDROME CRITICAL REGION 6 DGCR6 FAMILY MEMBER PROTEIN DGCR6L HUMAN|HGNC=12933|UniProtKB=Q9UQR1 Q9UQR1 ZNF148 PTHR24404:SF53 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 148 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=14247|UniProtKB=O75964 O75964 ATP5MG PTHR12386:SF12 ATP SYNTHASE SUBUNIT ATP SYNTHASE SUBUNIT G 2, MITOCHONDRIAL-RELATED ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleoside triphosphate metabolic process#GO:0009205;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ribose phosphate biosynthetic process#GO:0046390;ion transmembrane transport#GO:0034220;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide biosynthetic process#GO:0009152 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;proton-transporting two-sector ATPase complex, proton-transporting domain#GO:0033177;organelle inner membrane#GO:0019866;mitochondrial proton-transporting ATP synthase complex#GO:0005753;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;proton-transporting two-sector ATPase complex#GO:0016469;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)#GO:0000276;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;proton-transporting ATP synthase complex, coupling factor F(o)#GO:0045263;proton-transporting ATP synthase complex#GO:0045259 ATP synthase#PC00002 HUMAN|HGNC=4796|UniProtKB=P46952 P46952 HAAO PTHR15497:SF1 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE oxygenase#PC00177 HUMAN|HGNC=38675|UniProtKB=Q7Z7L8 Q7Z7L8 C11orf96 PTHR40250:SF1 CHROMOSOME 11 OPEN READING FRAME 96 CHROMOSOME 11 OPEN READING FRAME 96 HUMAN|HGNC=25318|UniProtKB=Q6P2I3 Q6P2I3 FAHD2B PTHR42796:SF3 FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836 hydrolase#PC00121 HUMAN|HGNC=5384|UniProtKB=P50213 P50213 IDH3A PTHR11835:SF34 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;oxidation-reduction process#GO:0055114;secondary alcohol metabolic process#GO:1902652;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 HUMAN|HGNC=16740|UniProtKB=O95625 O95625 ZBTB11 PTHR24384:SF196 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 11 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=26438|UniProtKB=Q4KMG9 Q4KMG9 TMEM52B PTHR33955:SF1 TRANSMEMBRANE PROTEIN 52 TRANSMEMBRANE PROTEIN 52B HUMAN|HGNC=17515|UniProtKB=Q8WWW8 Q8WWW8 GAB3 PTHR45960:SF3 GRB2-ASSOCIATED-BINDING PROTEIN GRB2-ASSOCIATED-BINDING PROTEIN 3 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Gab#P00563 HUMAN|HGNC=17777|UniProtKB=O94941 O94941 UBOX5 PTHR13492:SF2 RING FINGER PROTEIN 37 RING FINGER PROTEIN 37 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=13160|UniProtKB=Q03923 Q03923 ZNF85 PTHR24384:SF110 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 85-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=23992|UniProtKB=Q96DX8 Q96DX8 RTP4 PTHR14402:SF8 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 4 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein insertion into membrane#GO:0051205 HUMAN|HGNC=24959|UniProtKB=Q9BZM3 Q9BZM3 GSX2 PTHR47421:SF1 GS HOMEOBOX 2 GS HOMEOBOX 2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 homeodomain transcription factor#PC00119 HUMAN|HGNC=29898|UniProtKB=Q9C002 Q9C002 NMES1 PTHR14256:SF3 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT NORMAL MUCOSA OF ESOPHAGUS-SPECIFIC GENE 1 PROTEIN inorganic molecular entity transmembrane transporter activity#GO:0015318;transmembrane transporter activity#GO:0022857;electron transfer activity#GO:0009055;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277 oxidoreductase#PC00176 HUMAN|HGNC=31952|UniProtKB=A6NCF5 A6NCF5 KLHL33 PTHR45632:SF14 LD33804P KELCH-LIKE PROTEIN 33 HUMAN|HGNC=26632|UniProtKB=Q6P9A3 Q6P9A3 ZNF549 PTHR24377:SF690 IP01015P-RELATED ZINC FINGER PROTEIN 549 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28355|UniProtKB=Q86X40 Q86X40 LRRC28 PTHR45752:SF5 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 28 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11271|UniProtKB=O43610 O43610 SPRY3 PTHR12365:SF9 SPROUTY PROTEIN SPROUTY HOMOLOG 3 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;regulation of Ras protein signal transduction#GO:0046578;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;MAPK cascade#GO:0000165;protein modification process#GO:0036211;negative regulation of Ras protein signal transduction#GO:0046580;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;response to endogenous stimulus#GO:0009719;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of small GTPase mediated signal transduction#GO:0051058;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;negative regulation of MAP kinase activity#GO:0043407;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Spry#P00541;EGF receptor signaling pathway#P00018>SPRY#G01511;FGF signaling pathway#P00021>Spry#P00626 HUMAN|HGNC=2767|UniProtKB=O15263 O15263 DEFB4B PTHR20515:SF14 BETA-DEFENSIN BETA-DEFENSIN 4A receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;interspecies interaction between organisms#GO:0044419;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;localization#GO:0051179;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;response to chemical#GO:0042221;defense response to other organism#GO:0098542;response to other organism#GO:0051707;movement of cell or subcellular component#GO:0006928;defense response#GO:0006952;cell migration#GO:0016477;locomotion#GO:0040011;chemotaxis#GO:0006935;taxis#GO:0042330 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=23338|UniProtKB=Q5T8D3 Q5T8D3 ACBD5 PTHR23310:SF6 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5 transfer/carrier protein#PC00219 HUMAN|HGNC=9764|UniProtKB=Q9UL26 Q9UL26 RAB22A PTHR24073:SF910 DRAB5-RELATED RAS-RELATED PROTEIN RAB-22A GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;endocytosis#GO:0006897;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=18550|UniProtKB=Q9Y5U9 Q9Y5U9 IER3IP1 PTHR15858:SF0 UNCHARACTERIZED IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=24097|UniProtKB=Q8WWN8 Q8WWN8 ARAP3 PTHR45899:SF4 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 GTPase-activating protein#PC00257 HUMAN|HGNC=28610|UniProtKB=Q8IWA6 Q8IWA6 CCDC60 PTHR34754:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 60 COILED-COIL DOMAIN-CONTAINING PROTEIN 60 HUMAN|HGNC=6950|UniProtKB=P33993 P33993 MCM7 PTHR11630:SF26 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM7 DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;DNA-dependent ATPase activity#GO:0008094;sequence-specific double-stranded DNA binding#GO:1990837;pyrophosphatase activity#GO:0016462;sequence-specific DNA binding#GO:0043565;3'-5' DNA helicase activity#GO:0043138;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;DNA duplex unwinding#GO:0032508;protein-containing complex subunit organization#GO:0043933;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;nuclear DNA replication#GO:0033260;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;pre-replicative complex assembly involved in nuclear cell cycle DNA replication#GO:0006267;DNA unwinding involved in DNA replication#GO:0006268;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;organic cyclic compound biosynthetic process#GO:1901362;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;MCM core complex#GO:0097373;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=14937|UniProtKB=Q96S52 Q96S52 PIGS PTHR21072:SF13 GPI TRANSAMIDASE COMPONENT PIG-S GPI TRANSAMIDASE COMPONENT PIG-S HUMAN|HGNC=25099|UniProtKB=Q6P2P2 Q6P2P2 PRMT9 PTHR11006:SF60 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 9 N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 protein modifying enzyme#PC00260 HUMAN|HGNC=3170|UniProtKB=O95977 O95977 S1PR4 PTHR22750:SF13 G-PROTEIN COUPLED RECEPTOR SPHINGOSINE 1-PHOSPHATE RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=1618|UniProtKB=P48643 P48643 CCT5 PTHR11353:SF186 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT EPSILON protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;chaperone complex#GO:0101031;cellular anatomical entity#GO:0110165;chaperonin-containing T-complex#GO:0005832;intracellular#GO:0005622 chaperonin#PC00073 HUMAN|HGNC=25094|UniProtKB=Q765P7 Q765P7 MTSS2 PTHR15708:SF8 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED PROTEIN MTSS 2 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=26550|UniProtKB=Q96M43 Q96M43 NBPF4 PTHR14199:SF29 UNCHARACTERIZED NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 4-RELATED HUMAN|HGNC=27089|UniProtKB=Q6F5E8 Q6F5E8 CARMIL2 PTHR24112:SF32 LEUCINE-RICH REPEAT, ISOFORM F-RELATED CAPPING PROTEIN, ARP2/3 AND MYOSIN-I LINKER PROTEIN 2 HUMAN|HGNC=25250|UniProtKB=Q9BRR6 Q9BRR6 ADPGK PTHR21208:SF0 ADP-DEPENDENT GLUCOKINASE ADP-DEPENDENT GLUCOKINASE kinase#PC00137 HUMAN|HGNC=10690|UniProtKB=O95810 O95810 CAVIN2 PTHR15240:SF1 CAVIN CAVEOLAE-ASSOCIATED PROTEIN 2 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cytoplasm#GO:0005737;plasma membrane raft#GO:0044853;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane raft#GO:0045121;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;membrane region#GO:0098589;membrane microdomain#GO:0098857;whole membrane#GO:0098805;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=3500|UniProtKB=P34910 P34910 EVI2B PTHR15384:SF0 PROTEIN EVI2B PROTEIN EVI2B cell division#GO:0051301;animal organ development#GO:0048513;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;regulation of multicellular organismal development#GO:2000026;regulation of cell division#GO:0051302;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;system development#GO:0048731;regulation of hemopoiesis#GO:1903706;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;positive regulation of cell differentiation#GO:0045597;immune system development#GO:0002520;multicellular organism development#GO:0007275;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;immune system process#GO:0002376;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of multicellular organismal process#GO:0051240 HUMAN|HGNC=21398|UniProtKB=Q9BV23 Q9BV23 ABHD6 PTHR43798:SF5 MONOACYLGLYCEROL LIPASE MONOACYLGLYCEROL LIPASE ABHD6 lipase#PC00143 HUMAN|HGNC=24583|UniProtKB=Q7L591 Q7L591 DOK3 PTHR21258:SF42 DOCKING PROTEIN RELATED DOCKING PROTEIN 3 Angiogenesis#P00005>Dok-R#P00180 HUMAN|HGNC=6949|UniProtKB=Q14566 Q14566 MCM6 PTHR11630:SF73 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM6 DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;DNA-dependent ATPase activity#GO:0008094;sequence-specific double-stranded DNA binding#GO:1990837;pyrophosphatase activity#GO:0016462;sequence-specific DNA binding#GO:0043565;3'-5' DNA helicase activity#GO:0043138;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;nuclear DNA replication#GO:0033260;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;mitotic DNA replication#GO:1902969;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;DNA duplex unwinding#GO:0032508;mitotic nuclear division#GO:0140014;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;DNA unwinding involved in DNA replication#GO:0006268;pre-replicative complex assembly involved in nuclear cell cycle DNA replication#GO:0006267;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;organelle fission#GO:0048285;cell cycle#GO:0007049;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;MCM core complex#GO:0097373;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=29808|UniProtKB=Q9BYE2 Q9BYE2 TMPRSS13 PTHR24253:SF55 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 13 serine protease#PC00203 HUMAN|HGNC=7159|UniProtKB=P45452 P45452 MMP13 PTHR10201:SF165 MATRIX METALLOPROTEINASE COLLAGENASE 3 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 tissue remodeling#GO:0048771;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;response to hypoxia#GO:0001666;extracellular structure organization#GO:0043062;response to stress#GO:0006950;response to decreased oxygen levels#GO:0036293;catabolic process#GO:0009056;multicellular organismal process#GO:0032501;cellular component organization#GO:0016043;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;response to oxygen levels#GO:0070482;metabolic process#GO:0008152 metalloprotease#PC00153 Plasminogen activating cascade#P00050>MMP-13#P01250;Plasminogen activating cascade#P00050>pro-MMP-13#P01254;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=14909|UniProtKB=Q9NYW7 Q9NYW7 TAS2R1 PTHR11394:SF47 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 1-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=12929|UniProtKB=P35227 P35227 PCGF2 PTHR10825:SF31 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP RING FINGER PROTEIN 2 chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;histone ubiquitination#GO:0016574;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;histone H2A ubiquitination#GO:0033522;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 HUMAN|HGNC=10313|UniProtKB=P46778 P46778 RPL21 PTHR20981:SF8 60S RIBOSOMAL PROTEIN L21 60S RIBOSOMAL PROTEIN L21 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=14651|UniProtKB=O43447 O43447 PPIH PTHR11071:SF443 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=23228|UniProtKB=Q8IZJ3 Q8IZJ3 CPAMD8 PTHR11412:SF139 MACROGLOBULIN / COMPLEMENT C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PROTEIN 8 protease inhibitor#PC00191 HUMAN|HGNC=26192|UniProtKB=Q9H6A0 Q9H6A0 DENND2D PTHR15288:SF2 SUPPRESSION OF TUMORIGENICITY 5 ST5 DENN DOMAIN-CONTAINING PROTEIN 2D Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rab guanyl-nucleotide exchange factor activity#GO:0017112;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29635|UniProtKB=A6BM72 A6BM72 MEGF11 PTHR24035:SF127 MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN MULTIPLE EPIDERMAL GROWTH FACTOR-LIKE DOMAINS PROTEIN 11 extracellular matrix protein#PC00102 HUMAN|HGNC=29351|UniProtKB=Q9C0H5 Q9C0H5 ARHGAP39 PTHR45876:SF1 FI04035P RHO GTPASE-ACTIVATING PROTEIN 39 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=10914|UniProtKB=Q9UHW9 Q9UHW9 SLC12A6 PTHR11827:SF66 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 6 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;chemical synaptic transmission#GO:0007268;ion homeostasis#GO:0050801;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;signaling#GO:0023052;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cell communication#GO:0007154;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;regulation of cellular component size#GO:0032535;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065 secondary carrier transporter#PC00258 HUMAN|HGNC=11066|UniProtKB=Q9UHI5 Q9UHI5 SLC7A8 PTHR11785:SF113 AMINO ACID TRANSPORTER LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 transporter#PC00227 HUMAN|HGNC=392|UniProtKB=P31751 P31751 AKT2 PTHR24356:SF176 SERINE/THREONINE-PROTEIN KINASE RAC-BETA SERINE/THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 Angiogenesis#P00005>Akt#P00223;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AKT#P00827;p53 pathway#P00059>Akt#P01486;Interleukin signaling pathway#P00036>PKB#P00973;Huntington disease#P00029>Akt#P00805;Apoptosis signaling pathway#P00006>AKT#P00260;p53 pathway by glucose deprivation#P04397>Akt#P04641;FGF signaling pathway#P00021>Akt#P00632;EGF receptor signaling pathway#P00018>Akt#P00551;Hypoxia response via HIF activation#P00030>AKT#P00819;p53 pathway feedback loops 2#P04398>AKT#P04665;T cell activation#P00053>Akt#P01332;PI3 kinase pathway#P00048>PKB#P01179;FAS signaling pathway#P00020>ASK1#P00614;PDGF signaling pathway#P00047>PKB#P01151;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>AKT#P00894;Endothelin signaling pathway#P00019>Akt#P00589 HUMAN|HGNC=26004|UniProtKB=Q9H9A6 Q9H9A6 LRRC40 PTHR45752:SF160 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT-CONTAINING PROTEIN 40 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11169|UniProtKB=Q13425 Q13425 SNTB2 PTHR10554:SF8 SYNTROPHIN BETA-2-SYNTROPHIN membrane protein complex#GO:0098796;synapse#GO:0045202;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=37094|UniProtKB=P0CG39 P0CG39 POTEJ PTHR24118:SF56 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER I-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=11078|UniProtKB=Q14940 Q14940 SLC9A5 PTHR10110:SF56 SODIUM/HYDROGEN EXCHANGER SODIUM/HYDROGEN EXCHANGER 5 secondary carrier transporter#PC00258 HUMAN|HGNC=52681|UniProtKB=A0A5F9ZHS7 A0A5F9ZHS7 NFILZ PTHR15284:SF6 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN NFIL3 LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;rhythmic process#GO:0048511;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;circadian rhythm#GO:0007623;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=29443|UniProtKB=Q8N4N8 Q8N4N8 KIF2B PTHR24115:SF524 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF2B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;spindle#GO:0005819 microtubule binding motor protein#PC00156 HUMAN|HGNC=11200|UniProtKB=Q06945 Q06945 SOX4 PTHR10270:SF27 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-4 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=24868|UniProtKB=Q8WZA9 Q8WZA9 IRGQ PTHR19364:SF2 IMMUNITY-RELATED GTPASE FAMILY Q PROTEIN IMMUNITY-RELATED GTPASE FAMILY Q PROTEIN HUMAN|HGNC=7980|UniProtKB=P22736 P22736 NR4A1 PTHR24085:SF1 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;double-stranded DNA binding#GO:0003690;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;signaling receptor binding#GO:0005102;DNA-binding transcription factor binding#GO:0140297;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;protein binding#GO:0005515;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;hormone receptor binding#GO:0051427 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;response to peptide hormone#GO:0043434;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;cellular response to peptide#GO:1901653;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 Gonadotropin-releasing hormone receptor pathway#P06664>Nur77#P06713;Gonadotropin-releasing hormone receptor pathway#P06664>Nur77#G06893;CCKR signaling map#P06959>NR4A1#G07289;CCKR signaling map#P06959>NR4A1#G06995;Gonadotropin-releasing hormone receptor pathway#P06664>Nur77#G06679 HUMAN|HGNC=3687|UniProtKB=P31371 P31371 FGF9 PTHR11486:SF28 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 9 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;epithelial cell proliferation#GO:0050673;positive regulation of epithelial cell proliferation#GO:0050679;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;tube development#GO:0035295;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=30812|UniProtKB=Q562F6 Q562F6 SGO2 PTHR21577:SF5 SHUGOSHIN SHUGOSHIN 2 homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;meiotic sister chromatid segregation#GO:0045144;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;M phase#GO:0000279;sister chromatid cohesion#GO:0007062;chromosome organization involved in meiotic cell cycle#GO:0070192;mitotic cell cycle#GO:0000278;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;cell cycle phase#GO:0022403;meiosis I#GO:0007127;meiosis I cell cycle phase#GO:0098764;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;chromosome organization#GO:0051276;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;cell cycle#GO:0007049;organelle fission#GO:0048285;biological phase#GO:0044848 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 centromere DNA-binding protein#PC00071 HUMAN|HGNC=18335|UniProtKB=Q8IY51 Q8IY51 TIGD4 PTHR19303:SF18 TRANSPOSON TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 HUMAN|HGNC=693|UniProtKB=P36404 P36404 ARL2 PTHR45697:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;microtubule polymerization or depolymerization#GO:0031109;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29943|UniProtKB=Q9NT68 Q9NT68 TENM2 PTHR11219:SF8 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-2 identical protein binding#GO:0042802;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein homodimerization activity#GO:0042803;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=9851|UniProtKB=O60518 O60518 RANBP6 PTHR10527:SF16 IMPORTIN BETA RAN-BINDING PROTEIN 6 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=6144|UniProtKB=P53708 P53708 ITGA8 PTHR23220:SF5 INTEGRIN ALPHA INTEGRIN ALPHA-8 integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941;Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=26421|UniProtKB=Q96NG8 Q96NG8 ZNF582 PTHR24381:SF115 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 582 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25540|UniProtKB=Q9HCE6 Q9HCE6 ARHGEF10L PTHR12877:SF16 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 10-LIKE PROTEIN Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;regulation of nitrogen compound metabolic process#GO:0051171;contractile actin filament bundle assembly#GO:0030038;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;transcription, DNA-templated#GO:0006351;actin filament-based process#GO:0030029;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;cytoskeleton organization#GO:0007010;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cell communication#GO:0007154;actomyosin structure organization#GO:0031032;cellular nitrogen compound metabolic process#GO:0034641;actin filament bundle organization#GO:0061572;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of organelle organization#GO:0010638;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;supramolecular fiber organization#GO:0097435;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;stress fiber assembly#GO:0043149;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of supramolecular fiber organization#GO:1902903;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of cytoskeleton organization#GO:0051495;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;actin cytoskeleton organization#GO:0030036;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=23087|UniProtKB=Q8N370 Q8N370 SLC43A2 PTHR20766:SF2 FAMILY NOT NAMED LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;neutral amino acid transport#GO:0015804;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 HUMAN|HGNC=26868|UniProtKB=Q8N7R7 Q8N7R7 CCNYL1 PTHR14248:SF32 CYCLIN Y, ISOFORM A CYCLIN-Y-LIKE PROTEIN 1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;positive regulation of cell cycle#GO:0045787;positive regulation of protein modification process#GO:0031401;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 HUMAN|HGNC=2376|UniProtKB=O95402 O95402 MED26 PTHR15201:SF1 CRSP70 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 transcription cofactor#PC00217 HUMAN|HGNC=2417|UniProtKB=P22914 P22914 CRYGS PTHR11818:SF6 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN S structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=1020|UniProtKB=Q9Y276 Q9Y276 BCS1L PTHR23070:SF151 BCS1 AAA-TYPE ATPASE MITOCHONDRIAL CHAPERONE BCS1 HUMAN|HGNC=33628|UniProtKB=A6NLJ0 A6NLJ0 C2CD4B PTHR47226:SF1 C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4A C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4B HUMAN|HGNC=2121|UniProtKB=Q99788 Q99788 CMKLR1 PTHR24225:SF49 CHEMOTACTIC RECEPTOR CHEMOKINE-LIKE RECEPTOR 1 complement binding#GO:0001848;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 immune response-regulating signaling pathway#GO:0002764;inorganic ion homeostasis#GO:0098771;activation of immune response#GO:0002253;calcium-mediated signaling#GO:0019722;divalent inorganic cation homeostasis#GO:0072507;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of localization#GO:0032879;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;positive regulation of cellular component movement#GO:0051272;positive regulation of chemotaxis#GO:0050921;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;regulation of cell migration#GO:0030334;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;immune response-activating signal transduction#GO:0002757;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;defense response#GO:0006952;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of cellular component movement#GO:0051270;cellular cation homeostasis#GO:0030003;macrophage chemotaxis#GO:0048246;immune response-regulating cell surface receptor signaling pathway#GO:0002768;positive regulation of response to external stimulus#GO:0032103;regulation of phospholipase C activity#GO:1900274;regulation of immune response#GO:0050776;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of cellular process#GO:0050794;movement of cell or subcellular component#GO:0006928;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;metal ion homeostasis#GO:0055065;locomotion#GO:0040011;taxis#GO:0042330;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of locomotion#GO:0040012;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;positive regulation of leukocyte migration#GO:0002687;positive regulation of response to stimulus#GO:0048584;granulocyte chemotaxis#GO:0071621;ion homeostasis#GO:0050801;regulation of chemotaxis#GO:0050920;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;myeloid leukocyte migration#GO:0097529;cellular divalent inorganic cation homeostasis#GO:0072503;regulation of immune system process#GO:0002682;signaling#GO:0023052;chemotaxis#GO:0006935;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;regulation of cell motility#GO:2000145;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;positive regulation of immune system process#GO:0002684;homeostatic process#GO:0042592;cell motility#GO:0048870;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cell chemotaxis#GO:0060326;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of leukocyte chemotaxis#GO:0002690;cell migration#GO:0016477 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=26881|UniProtKB=Q17RS7 Q17RS7 GEN1 PTHR11081:SF54 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE GEN HOMOLOG 1 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;endodeoxyribonuclease activity#GO:0004520;deoxyribonuclease activity#GO:0004536 exodeoxyribonuclease#PC00098 HUMAN|HGNC=30891|UniProtKB=A8MYA2 A8MYA2 CXorf49 PTHR31866:SF5 GENE 4779-RELATED SUBFAMILY NOT NAMED HUMAN|HGNC=37254|UniProtKB=A1L168 A1L168 C20orf202 PTHR32289:SF5 PROTEIN FAM167A TRANSMEMBRANE 74B, OPPOSITE STRAND HUMAN|HGNC=28960|UniProtKB=Q14667 Q14667 KIAA0100 PTHR15678:SF6 ANTIGEN MLAA-22-RELATED PROTEIN KIAA0100 HUMAN|HGNC=18707|UniProtKB=Q7Z6J2 Q7Z6J2 TAMALIN PTHR15963:SF3 GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED PROTEIN TAMALIN HUMAN|HGNC=2261|UniProtKB=Q9Y6N1 Q9Y6N1 COX11 PTHR21320:SF3 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL-RELATED chaperone#PC00072 HUMAN|HGNC=28203|UniProtKB=Q9BR77 Q9BR77 CCDC77 PTHR22091:SF1 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 77 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 HUMAN|HGNC=25165|UniProtKB=Q6NUI6 Q6NUI6 CHADL PTHR24373:SF284 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN CHONDROADHERIN-LIKE PROTEIN extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=23785|UniProtKB=Q9Y2I7 Q9Y2I7 PIKFYVE PTHR46715:SF1 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE kinase#PC00137 HUMAN|HGNC=244|UniProtKB=P35612 P35612 ADD2 PTHR10672:SF6 ADDUCIN BETA-ADDUCIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 plasma membrane raft#GO:0044853;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;asymmetric synapse#GO:0032279;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;plasma membrane region#GO:0098590;postsynapse#GO:0098794;membrane raft#GO:0045121;cytoskeleton#GO:0005856;membrane region#GO:0098589;membrane microdomain#GO:0098857;plasma membrane#GO:0005886 non-motor actin binding protein#PC00165 HUMAN|HGNC=2231|UniProtKB=P53618 P53618 COPB1 PTHR10635:SF0 COATOMER SUBUNIT BETA COATOMER SUBUNIT BETA localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;COPI vesicle coat#GO:0030126;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=25186|UniProtKB=Q5SV17 Q5SV17 TMEM240 PTHR28666:SF1 TRANSMEMBRANE PROTEIN 240 TRANSMEMBRANE PROTEIN 240 HUMAN|HGNC=12327|UniProtKB=Q12815 Q12815 TROAP PTHR15289:SF3 TASTIN TASTIN HUMAN|HGNC=11127|UniProtKB=Q9BZZ2 Q9BZZ2 SIGLEC1 PTHR47243:SF1 SIALOADHESIN SIALOADHESIN HUMAN|HGNC=12114|UniProtKB=A0A075B6X5 A0A075B6X5 TRAV18 PTHR23267:SF438 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 18 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=30422|UniProtKB=Q8TF72 Q8TF72 SHROOM3 PTHR15012:SF33 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cortical cytoskeleton#GO:0030863;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;apical junction complex#GO:0043296 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=1184|UniProtKB=Q9NQ89 Q9NQ89 C12orf4 PTHR16525:SF0 UNCHARACTERIZED PROTEIN C12ORF4 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=10698|UniProtKB=Q92503 Q92503 SEC14L1 PTHR23324:SF51 SEC14 RELATED PROTEIN SEC14-LIKE PROTEIN 1 HUMAN|HGNC=37265|UniProtKB=P0CJ89 P0CJ89 DUX4L6 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=25732|UniProtKB=Q9H0H3 Q9H0H3 KLHL25 PTHR24410:SF10 HL07962P-RELATED KELCH-LIKE PROTEIN 25 HUMAN|HGNC=6893|UniProtKB=P10636 P10636 MAPT PTHR11501:SF14 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN TAU cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;multicellular organism development#GO:0007275;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;neuron development#GO:0048666;generation of neurons#GO:0048699 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=11411|UniProtKB=O76039 O76039 CDKL5 PTHR24056:SF111 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 5 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;dendrite development#GO:0016358;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;organic substance metabolic process#GO:0071704;positive regulation of growth#GO:0045927;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;positive regulation of cell growth#GO:0030307;positive regulation of multicellular organismal process#GO:0051240;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;positive regulation of cell projection organization#GO:0031346;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;growth#GO:0040007;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;axon extension#GO:0048675;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;protein metabolic process#GO:0019538;cell part morphogenesis#GO:0032990;regulation of cell growth#GO:0001558;metabolic process#GO:0008152;regulation of anatomical structure size#GO:0090066;positive regulation of neuron differentiation#GO:0045666;developmental cell growth#GO:0048588;developmental growth involved in morphogenesis#GO:0060560;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;developmental growth#GO:0048589;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;cell growth#GO:0016049;positive regulation of developmental process#GO:0051094;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699 somatodendritic compartment#GO:0036477;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;dendrite#GO:0030425;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=4088|UniProtKB=Q99928 Q99928 GABRG3 PTHR18945:SF195 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-3 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;cell junction#GO:0030054;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=8688|UniProtKB=Q9Y5E6 Q9Y5E6 PCDHB3 PTHR24028:SF302 CADHERIN-87A PROTOCADHERIN BETA-3 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=41980|UniProtKB=E9PKD4 E9PKD4 NPIPA5 PTHR15438:SF14 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER A1-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=19891|UniProtKB=Q86UT5 Q86UT5 PDZD3 PTHR14191:SF20 PDZ DOMAIN CONTAINING PROTEIN NA(+)/H(+) EXCHANGE REGULATORY COFACTOR NHE-RF4 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;protein localization to plasma membrane#GO:0072659;protein localization to cell periphery#GO:1990778;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical part of cell#GO:0045177;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324 HUMAN|HGNC=1814|UniProtKB=P13688 P13688 CEACAM1 PTHR44427:SF1 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1-RELATED HUMAN|HGNC=9846|UniProtKB=P62826 P62826 RAN PTHR24071:SF37 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;ribosome biogenesis#GO:0042254;protein localization to organelle#GO:0033365;protein import#GO:0017038;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;ribonucleoprotein complex biogenesis#GO:0022613;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 small GTPase#PC00208 HUMAN|HGNC=21043|UniProtKB=Q9BZ71 Q9BZ71 PITPNM3 PTHR23509:SF22 PA-PL1 PHOSPHOLIPASE FAMILY MEMBRANE-ASSOCIATED PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi-associated vesicle#GO:0005798;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229 phospholipase#PC00186 HUMAN|HGNC=44367|UniProtKB=Q6IED9 Q6IED9 DGAT2L7P PTHR12317:SF10 DIACYLGLYCEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 2-LIKE PROTEIN DGAT2L7P-RELATED transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;primary metabolic process#GO:0044238;neutral lipid metabolic process#GO:0006638;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=2422|UniProtKB=O75390 O75390 CS PTHR11739:SF8 CITRATE SYNTHASE CITRATE SYNTHASE, MITOCHONDRIAL transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transferase#PC00220 Pyruvate metabolism#P02772>Citrate Synthetase#P03141;TCA cycle#P00051>Citrate Synthase#P01267 HUMAN|HGNC=5173|UniProtKB=P01112 P01112 HRAS PTHR24070:SF385 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE HRAS GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;FGF signaling pathway#P00021>Ras#P00633;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552;Angiogenesis#P00005>Ras#P00238;T cell activation#P00053>Ras#P01306;B cell activation#P00010>Ras#P00376;Gonadotropin-releasing hormone receptor pathway#P06664>Ras#P06753;Ras Pathway#P04393>Ras#P04547;PI3 kinase pathway#P00048>Ras#P01182;p53 pathway feedback loops 2#P04398>Ras#P04651;Integrin signalling pathway#P00034>Ras#P00916;VEGF signaling pathway#P00056>Ras#P01411 HUMAN|HGNC=31326|UniProtKB=Q8WWM7 Q8WWM7 ATXN2L PTHR12854:SF8 ATAXIN 2-RELATED ATAXIN-2-LIKE PROTEIN nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 organelle assembly#GO:0070925;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of organelle organization#GO:0033043;biological regulation#GO:0065007;cytoplasmic mRNA processing body assembly#GO:0033962;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA metabolism protein#PC00031 HUMAN|HGNC=713|UniProtKB=P15289 P15289 ARSA PTHR42693:SF11 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE A hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=24715|UniProtKB=Q0IIM8 Q0IIM8 TBC1D8B PTHR22957:SF320 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 8B GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=30584|UniProtKB=P0DJJ0 P0DJJ0 SRGAP2C PTHR14166:SF6 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 2-RELATED Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048 regulation of cellular component movement#GO:0051270;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;localization of cell#GO:0051674;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of cell motility#GO:2000146;cell migration#GO:0016477;locomotion#GO:0040011;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=6267|UniProtKB=P48051 P48051 KCNJ6 PTHR11767:SF19 INWARD RECTIFIER POTASSIUM CHANNEL G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GIRK#P00724;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>GIRK#P01083 HUMAN|HGNC=15980|UniProtKB=Q96A58 Q96A58 RERG PTHR24070:SF373 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED AND ESTROGEN-REGULATED GROWTH INHIBITOR GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 PDGF signaling pathway#P00047>Ras#P01154 HUMAN|HGNC=13276|UniProtKB=O14681 O14681 EI24 PTHR21389:SF0 P53 INDUCED PROTEIN ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG process utilizing autophagic mechanism#GO:0061919;macroautophagy#GO:0016236;cellular metabolic process#GO:0044237;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=21568|UniProtKB=Q8N5C1 Q8N5C1 CALHM5 PTHR32261:SF8 CALCIUM HOMEOSTASIS MODULATOR PROTEIN CALCIUM HOMEOSTASIS MODULATOR PROTEIN 5 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=12831|UniProtKB=Q13426 Q13426 XRCC4 PTHR28559:SF1 DNA REPAIR PROTEIN XRCC4 DNA REPAIR PROTEIN XRCC4 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;response to ionizing radiation#GO:0010212;macromolecule metabolic process#GO:0043170;positive regulation of catalytic activity#GO:0043085;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;double-strand break repair via nonhomologous end joining#GO:0006303;response to stress#GO:0006950;biological regulation#GO:0065007;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=19681|UniProtKB=Q9UII6 Q9UII6 DUSP13 PTHR45682:SF10 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE 13 ISOFORM B Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=9197|UniProtKB=P52435 P52435 POLR2J PTHR13946:SF31 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A-RELATED catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;DNA-directed 5'-3' RNA polymerase activity#GO:0003899;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 membrane-enclosed lumen#GO:0031974;RNA polymerase II, core complex#GO:0005665;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=18806|UniProtKB=Q9Y6Y1 Q9Y6Y1 CAMTA1 PTHR23335:SF11 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 1 nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=28300|UniProtKB=Q969T7 Q969T7 NT5C3B PTHR13045:SF0 5'-NUCLEOTIDASE 7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE esterase#PC00097 HUMAN|HGNC=5927|UniProtKB=P01721 P01721 IGLV6-57 PTHR23267:SF108 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 6-57 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=3059|UniProtKB=Q99075 Q99075 HBEGF PTHR10740:SF4 TRANSFORMING GROWTH FACTOR ALPHA PROHEPARIN-BINDING EGF-LIKE GROWTH FACTOR regulation of protein modification process#GO:0031399;regulation of mitotic nuclear division#GO:0007088;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of organelle organization#GO:0033043;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell cycle process#GO:0090068;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;organelle fission#GO:0048285;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of mitotic cell cycle#GO:0007346 growth factor#PC00112 CCKR signaling map#P06959>HBEGF#G07261;EGF receptor signaling pathway#P00018>EGF#P00549;CCKR signaling map#P06959>HBEGF#G06968;CCKR signaling map#P06959>Pro HBEGF#P07182;CCKR signaling map#P06959>HBEGF#P07025 HUMAN|HGNC=26489|UniProtKB=Q6P9G4 Q6P9G4 TMEM154 PTHR36526:SF1 TRANSMEMBRANE PROTEIN 154 TRANSMEMBRANE PROTEIN 154 HUMAN|HGNC=23678|UniProtKB=B1ANY3 B1ANY3 FAM220BP PTHR31980:SF2 PROTEIN FAM220A PROTEIN FAM220BP-RELATED protein binding#GO:0005515;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=7546|UniProtKB=Q9BQG0 Q9BQG0 MYBBP1A PTHR13213:SF2 MYB-BINDING PROTEIN 1A FAMILY MEMBER MYB-BINDING PROTEIN 1A intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=8003|UniProtKB=Q8IXM6 Q8IXM6 NRM PTHR31040:SF1 NURIM NURIM HUMAN|HGNC=25178|UniProtKB=Q96CP2 Q96CP2 FLYWCH2 PTHR31665:SF0 FLYWCH FAMILY MEMBER 2-RELATED FLYWCH FAMILY MEMBER 2 HUMAN|HGNC=13598|UniProtKB=Q9UKC9 Q9UKC9 FBXL2 PTHR13318:SF44 UNCHARACTERIZED F-BOX/LRR-REPEAT PROTEIN 2 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=30890|UniProtKB=Q8TCY9 Q8TCY9 URGCP PTHR22796:SF13 URG4-RELATED UP-REGULATOR OF CELL PROLIFERATION HUMAN|Ensembl=ENSG00000274971|UniProtKB=A0A0G2JMM0 A0A0G2JMM0 ENSG00000274971 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=18037|UniProtKB=Q68CP9 Q68CP9 ARID2 PTHR22970:SF14 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=11270|UniProtKB=O43597 O43597 SPRY2 PTHR12365:SF8 SPROUTY PROTEIN SPROUTY HOMOLOG 2 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;regulation of Ras protein signal transduction#GO:0046578;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;MAPK cascade#GO:0000165;protein modification process#GO:0036211;negative regulation of Ras protein signal transduction#GO:0046580;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;response to endogenous stimulus#GO:0009719;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of small GTPase mediated signal transduction#GO:0051058;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;negative regulation of MAP kinase activity#GO:0043407;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Spry#P00541;EGF receptor signaling pathway#P00018>SPRY#G01511;FGF signaling pathway#P00021>Spry#P00626 HUMAN|HGNC=17348|UniProtKB=O43395 O43395 PRPF3 PTHR14212:SF0 U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED U4/U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;Lsm2-8 complex#GO:0120115;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 mRNA splicing#P00058>U4#P01476;mRNA splicing#P00058>U6#P01473 HUMAN|HGNC=13345|UniProtKB=Q14693 Q14693 LPIN1 PTHR12181:SF10 LIPIN PHOSPHATIDATE PHOSPHATASE LPIN1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;catalytic activity#GO:0003824;transcription coactivator activity#GO:0003713;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;phosphoric ester hydrolase activity#GO:0042578 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;lipid catabolic process#GO:0016042;lipid biosynthetic process#GO:0008610;acylglycerol metabolic process#GO:0006639;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;neutral lipid metabolic process#GO:0006638;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;triglyceride biosynthetic process#GO:0019432;carboxylic acid catabolic process#GO:0046395;positive regulation of biological process#GO:0048518;cellular lipid catabolic process#GO:0044242;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nucleobase-containing compound biosynthetic process#GO:0034654;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;lipid metabolic process#GO:0006629;response to insulin#GO:0032868;positive regulation of RNA biosynthetic process#GO:1902680;response to peptide hormone#GO:0043434;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;glycerolipid metabolic process#GO:0046486;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;cellular response to insulin stimulus#GO:0032869;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;triglyceride metabolic process#GO:0006641;cellular response to chemical stimulus#GO:0070887;glycerolipid biosynthetic process#GO:0045017;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;fatty acid catabolic process#GO:0009062;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=29331|UniProtKB=Q9HCE0 Q9HCE0 EPG5 PTHR31139:SF4 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG ECTOPIC P GRANULES PROTEIN 5 HOMOLOG process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;protein-containing complex disassembly#GO:0032984;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagosome maturation#GO:0097352;cellular process#GO:0009987;autophagy#GO:0006914;cellular catabolic process#GO:0044248;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=15845|UniProtKB=Q8IXS6 Q8IXS6 PALM2 PTHR10498:SF10 PARALEMMIN-RELATED A-KINASE ANCHOR PROTEIN 2-RELATED HUMAN|HGNC=6535|UniProtKB=P00338 P00338 LDHA PTHR43128:SF10 L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) L-LACTATE DEHYDROGENASE A CHAIN oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092 HUMAN|HGNC=28511|UniProtKB=Q8NHS1 Q8NHS1 CLDND2 PTHR10671:SF30 EPITHELIAL MEMBRANE PROTEIN-RELATED CLAUDIN DOMAIN-CONTAINING PROTEIN 2 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=4983|UniProtKB=P09429 P09429 HMGB1 PTHR48112:SF11 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B1 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;DNA binding, bending#GO:0008301;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 p53 pathway#P00059>HMG1#P04619 HUMAN|HGNC=24502|UniProtKB=O43379 O43379 WDR62 PTHR45589:SF3 WD REPEAT DOMAIN 62, ISOFORM G WD REPEAT-CONTAINING PROTEIN 62 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;nervous system development#GO:0007399;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051 intracellular non-membrane-bounded organelle#GO:0043232;spindle pole#GO:0000922;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;spindle#GO:0005819;intracellular organelle#GO:0043229 HUMAN|HGNC=16053|UniProtKB=Q8N1V2 Q8N1V2 CFAP52 PTHR13720:SF14 WD-40 REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 52 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 HUMAN|Ensembl=ENSG00000288316|UniProtKB=A0A5F9ZH88 A0A5F9ZH88 ENSG00000288316 PTHR11738:SF113 MHC CLASS I NK CELL RECEPTOR KIR2DL PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=37267|UniProtKB=P0CJ85 P0CJ85 DUX4L2 PTHR46123:SF3 MIX-TYPE HOMEOBOX GENE 1-RELATED DOUBLE HOMEOBOX PROTEIN 1-RELATED homeodomain transcription factor#PC00119 HUMAN|HGNC=5579|UniProtKB=A0A0B4J2B6 A0A0B4J2B6 IGHV2OR16-5 PTHR23266:SF240 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=12949|UniProtKB=Q14119 Q14119 VEZF1 PTHR24379:SF75 KRAB AND ZINC FINGER DOMAIN-CONTAINING VASCULAR ENDOTHELIAL ZINC FINGER 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9256|UniProtKB=P45877 P45877 PPIC PTHR11071:SF11 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=26820|UniProtKB=Q6NT55 Q6NT55 CYP4F22 PTHR24291:SF53 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4F22 oxygenase#PC00177 HUMAN|HGNC=18539|UniProtKB=P61266 P61266 STX1B PTHR19957:SF334 SYNTAXIN SYNTAXIN-1B protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;secretion#GO:0046903;vesicle organization#GO:0016050;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;export from cell#GO:0140352;protein-containing complex localization#GO:0031503 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 SNARE protein#PC00034 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 HUMAN|HGNC=22215|UniProtKB=Q9P2G1 Q9P2G1 ANKIB1 PTHR11685:SF13 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING ANKYRIN REPEAT AND IBR DOMAIN-CONTAINING PROTEIN 1 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=28707|UniProtKB=Q9BTK6 Q9BTK6 PAGR1 PTHR28467:SF1 PAXIP1-ASSOCIATED GLUTAMATE-RICH PROTEIN 1 PAXIP1-ASSOCIATED GLUTAMATE-RICH PROTEIN 1 HUMAN|HGNC=32035|UniProtKB=Q96NU0 Q96NU0 CNTNAP3B PTHR15036:SF36 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN FAMILY MEMBER 3C-RELATED HUMAN|HGNC=21694|UniProtKB=P78424 P78424 POU6F2 PTHR11636:SF68 POU DOMAIN POU DOMAIN, CLASS 6, TRANSCRIPTION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=17036|UniProtKB=O75711 O75711 SCRG1 PTHR17463:SF0 SCRAPIE-RESPONSIVE PROTEIN 1 SCRG1 SCRAPIE-RESPONSIVE PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;neuron projection terminus#GO:0044306;intracellular#GO:0005622;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=25237|UniProtKB=Q9H1E5 Q9H1E5 TMX4 PTHR46107:SF1 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 4 HUMAN|HGNC=12768|UniProtKB=Q9H3P2 Q9H3P2 NELFA PTHR13328:SF4 NEGATIVE ELONGATION FACTOR A NELF-A NEGATIVE ELONGATION FACTOR A HUMAN|HGNC=3546|UniProtKB=P00451 P00451 F8 PTHR24543:SF320 MULTICOPPER OXIDASE-RELATED COAGULATION FACTOR VIII oxidoreductase#PC00176 Blood coagulation#P00011>FVIIIa#P00446;Blood coagulation#P00011>FVIII#P00405 HUMAN|HGNC=24167|UniProtKB=Q8TD06 Q8TD06 AGR3 PTHR15337:SF5 ANTERIOR GRADIENT PROTEIN-RELATED ANTERIOR GRADIENT PROTEIN 3 regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 reductase#PC00198 HUMAN|HGNC=11649|UniProtKB=O95988 O95988 TCL1B PTHR14060:SF2 PROTEIN P13 MTCP-1 T-CELL LEUKEMIA/LYMPHOMA PROTEIN 1B protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of protein modification process#GO:0031401;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=24076|UniProtKB=Q6AI08 Q6AI08 HEATR6 PTHR13366:SF0 MALARIA ANTIGEN-RELATED HEAT REPEAT-CONTAINING PROTEIN 6 HUMAN|HGNC=7958|UniProtKB=Q15761 Q15761 NPY5R PTHR24235:SF10 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR TYPE 5 G-protein coupled receptor#PC00021 HUMAN|HGNC=2244|UniProtKB=Q99807 Q99807 COQ7 PTHR11237:SF4 COENZYME Q10 BIOSYNTHESIS PROTEIN 7 5-DEMETHOXYUBIQUINONE HYDROXYLASE, MITOCHONDRIAL HUMAN|HGNC=10445|UniProtKB=Q92600 Q92600 CNOT9 PTHR12262:SF0 UNCHARACTERIZED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;intracellular#GO:0005622;CCR4-NOT complex#GO:0030014;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=1913|UniProtKB=P18754 P18754 RCC1 PTHR45982:SF1 REGULATOR OF CHROMOSOME CONDENSATION REGULATOR OF CHROMOSOME CONDENSATION HUMAN|HGNC=28644|UniProtKB=Q86UF2 Q86UF2 CTAGE6 PTHR23158:SF57 MELANOMA INHIBITORY ACTIVITY-RELATED CTAGE FAMILY MEMBER 15-RELATED endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=805|UniProtKB=P14415 P14415 ATP1B2 PTHR11523:SF26 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-2 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;enzyme activator activity#GO:0008047;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;ATPase activator activity#GO:0001671;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;potassium ion transport#GO:0006813;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;metal ion transport#GO:0030001;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725;export from cell#GO:0140352 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=11394|UniProtKB=O75716 O75716 STK16 PTHR45998:SF2 SERINE/THREONINE-PROTEIN KINASE 16 SERINE/THREONINE-PROTEIN KINASE 16 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=5910|UniProtKB=P01718 P01718 IGLV3-27 PTHR23267:SF375 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-27 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=29357|UniProtKB=Q9C0F0 Q9C0F0 ASXL3 PTHR13578:SF18 ADDITIONAL SEX COMBS LIKE PROTEIN ASXL POLYCOMB GROUP PROTEIN ASXL3-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=10752|UniProtKB=P63302 P63302 SELENOW PTHR15124:SF16 SELENOPROTEIN W SELENOPROTEIN W response to stimulus#GO:0050896;response to inorganic substance#GO:0010035;response to chemical#GO:0042221 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=11158|UniProtKB=P62314 P62314 SNRPD1 PTHR23338:SF18 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;cytoplasm#GO:0005737;SMN-Sm protein complex#GO:0034719;SMN complex#GO:0032797;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114;U12-type spliceosomal complex#GO:0005689 RNA splicing factor#PC00148 HUMAN|HGNC=1751|UniProtKB=P55289 P55289 CDH12 PTHR24027:SF96 CADHERIN-23 CADHERIN-12 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=5347|UniProtKB=Q14773 Q14773 ICAM4 PTHR13771:SF8 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 4 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=3145|UniProtKB=Q9NQA5 Q9NQA5 TRPV5 PTHR10582:SF11 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;divalent metal ion transport#GO:0070838;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=25593|UniProtKB=Q9H813 Q9H813 PACC1 PTHR16087:SF0 TRANSMEMBRANE PROTEIN 206 PROTON-ACTIVATED CHLORIDE CHANNEL HUMAN|HGNC=3976|UniProtKB=P02794 P02794 FTH1 PTHR11431:SF37 FERRITIN FERRITIN HEAVY CHAIN cation binding#GO:0043169;ferrous iron binding#GO:0008198;ferroxidase activity#GO:0004322;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;cellular cation homeostasis#GO:0030003;transition metal ion homeostasis#GO:0055076;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular iron ion homeostasis#GO:0006879;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;iron ion homeostasis#GO:0055072;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 storage protein#PC00210 HUMAN|HGNC=8247|UniProtKB=O95006 O95006 OR2F2 PTHR26453:SF63 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2F2 transmembrane signal receptor#PC00197 HUMAN|HGNC=9358|UniProtKB=P48147 P48147 PREP PTHR42881:SF2 PROLYL ENDOPEPTIDASE PROLYL ENDOPEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 serine protease#PC00203 Vasopressin synthesis#P04395>Endo Peptidase#P04596 HUMAN|HGNC=9516|UniProtKB=Q9UQ72 Q9UQ72 PSG11 PTHR44337:SF15 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 11-RELATED HUMAN|HGNC=12539|UniProtKB=Q9HAW7 Q9HAW7 UGT1A7 PTHR48050:SF6 STEROL 3-BETA-GLUCOSYLTRANSFERASE UDP-GLUCURONOSYLTRANSFERASE 1A10-RELATED glycosyltransferase#PC00111 HUMAN|HGNC=24641|UniProtKB=Q7Z3J2 Q7Z3J2 VPS35L PTHR13673:SF0 ESOPHAGEAL CANCER ASSOCIATED PROTEIN VPS35 ENDOSOMAL PROTEIN SORTING FACTOR-LIKE localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;retrograde transport, endosome to plasma membrane#GO:1990126;cellular process#GO:0009987 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=8774|UniProtKB=P54750 P54750 PDE1A PTHR11347:SF34 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CALCIUM/CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1A hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 CCKR signaling map#P06959>PDE#P07161 HUMAN|HGNC=5558|UniProtKB=P01742 P01742 IGHV1-69 PTHR23266:SF262 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 1-69-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=6526|UniProtKB=P80188 P80188 LCN2 PTHR11430:SF13 LIPOCALIN NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN binding#GO:0005488 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 HUMAN|HGNC=9381|UniProtKB=P22694 P22694 PRKACB PTHR24353:SF116 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT BETA carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein serine/threonine kinase activity#GO:0004674;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 GABA-B receptor II signaling#P05731>PKA#P05752;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;CCKR signaling map#P06959>PKA-Calpha/beta/gamma#P07099;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Enkephalin release#P05913>PKA#P05972;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>PKA-c#P00707;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Endothelin signaling pathway#P00019>PKA#P00570 HUMAN|HGNC=23113|UniProtKB=Q9HB65 Q9HB65 ELL3 PTHR23288:SF18 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL3 general transcription factor#PC00259 HUMAN|HGNC=14944|UniProtKB=Q6ZSY5 Q6ZSY5 PPP1R3F PTHR12307:SF40 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3F phosphatase binding#GO:0019902;enzyme binding#GO:0019899;protein binding#GO:0005515;protein phosphatase 1 binding#GO:0008157;carbohydrate binding#GO:0030246;protein phosphatase binding#GO:0019903;binding#GO:0005488 monosaccharide metabolic process#GO:0005996;glucan metabolic process#GO:0044042;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;energy derivation by oxidation of organic compounds#GO:0015980;regulation of biological process#GO:0050789;cellular glucan metabolic process#GO:0006073;glucan biosynthetic process#GO:0009250;regulation of biosynthetic process#GO:0009889;oxidation-reduction process#GO:0055114;regulation of macromolecule biosynthetic process#GO:0010556;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;glycogen metabolic process#GO:0005977;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glucose metabolic process#GO:0006006;glycogen biosynthetic process#GO:0005978;regulation of glucose metabolic process#GO:0010906;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;polysaccharide metabolic process#GO:0005976;regulation of cellular biosynthetic process#GO:0031326;cellular carbohydrate metabolic process#GO:0044262;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;hexose metabolic process#GO:0019318;energy reserve metabolic process#GO:0006112;cellular polysaccharide biosynthetic process#GO:0033692;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular polysaccharide metabolic process#GO:0044264;small molecule metabolic process#GO:0044281 protein serine/threonine phosphatase complex#GO:0008287;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 phosphatase modulator#PC00184 HUMAN|HGNC=13525|UniProtKB=Q9UQF0 Q9UQF0 ERVW-1 PTHR10424:SF48 VIRAL ENVELOPE PROTEIN SYNCYTIN-1 viral or transposable element protein#PC00237 HUMAN|HGNC=24319|UniProtKB=Q8IY22 Q8IY22 CMIP PTHR25480:SF199 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 73 C-MAF-INDUCING PROTEIN HUMAN|HGNC=4125|UniProtKB=Q14435 Q14435 GALNT3 PTHR11675:SF33 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 3 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=19684|UniProtKB=P0C1S8 P0C1S8 WEE2 PTHR11042:SF75 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 nuclear division#GO:0000280;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;telophase#GO:0051326;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;M phase#GO:0000279;meiotic cell cycle process#GO:1903046;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;cell cycle phase#GO:0022403;meiosis I#GO:0007127;meiosis I cell cycle phase#GO:0098764;regulation of nuclear division#GO:0051783;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of reproductive process#GO:2000241;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;regulation of cellular process#GO:0050794;meiotic cell cycle phase#GO:0098762;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;regulation of meiotic cell cycle#GO:0051445;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;biological phase#GO:0044848;cell cycle#GO:0007049 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=15495|UniProtKB=Q6PI73 Q6PI73 LILRA6 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 6-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=4583|UniProtKB=Q16478 Q16478 GRIK5 PTHR18966:SF351 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 5 amino acid binding#GO:0016597;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;molecular transducer activity#GO:0060089;ion binding#GO:0043167;anion binding#GO:0043168;sodium channel activity#GO:0005272;glutamate binding#GO:0016595;signaling receptor activity#GO:0038023;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;monovalent inorganic cation transmembrane transporter activity#GO:0015077;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;transporter activity#GO:0005215;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA#P01026;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Huntington disease#P00029>Kainate receptor#P00796;Metabotropic glutamate receptor group I pathway#P00041>GluR5#P01054;Ionotropic glutamate receptor pathway#P00037>KA5#P01000 HUMAN|HGNC=26957|UniProtKB=Q9NPB8 Q9NPB8 GPCPD1 PTHR22958:SF1 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;glycerolipid catabolic process#GO:0046503;glycerophospholipid catabolic process#GO:0046475;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphodiesterase#PC00185 HUMAN|HGNC=30031|UniProtKB=Q9BTU6 Q9BTU6 PI4K2A PTHR12865:SF7 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;Golgi organization#GO:0007030;endomembrane system organization#GO:0010256;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;cellular component organization#GO:0016043;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;glycerolipid metabolic process#GO:0046486;organelle organization#GO:0006996;vesicle organization#GO:0016050;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 kinase#PC00137 HUMAN|HGNC=15708|UniProtKB=Q8TEZ7 Q8TEZ7 PAQR8 PTHR20855:SF22 ADIPOR/PROGESTIN RECEPTOR-RELATED MEMBRANE PROGESTIN RECEPTOR BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496 response to organic substance#GO:0010033;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to organic cyclic compound#GO:0014070;response to hormone#GO:0009725;response to chemical#GO:0042221;response to lipid#GO:0033993;response to steroid hormone#GO:0048545 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=11756|UniProtKB=Q03403 Q03403 TFF2 PTHR13826:SF17 INTESTINAL TREFOIL FACTOR-RELATED TREFOIL FACTOR 2 digestion#GO:0007586;multicellular organismal homeostasis#GO:0048871;tissue homeostasis#GO:0001894;regulation of biological quality#GO:0065008;system process#GO:0003008;biological regulation#GO:0065007;homeostatic process#GO:0042592;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 CCKR signaling map#P06959>TFF2#G07264;CCKR signaling map#P06959>TFF2#G06971 HUMAN|HGNC=33434|UniProtKB=Q9Y6U7 Q9Y6U7 RNF215 PTHR22765:SF345 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING RING FINGER PROTEIN 215 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=28122|UniProtKB=Q9BRG1 Q9BRG1 VPS25 PTHR13149:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS25 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 25 identical protein binding#GO:0042802;protein binding#GO:0005515;protein homodimerization activity#GO:0042803;binding#GO:0005488 protein catabolic process in the vacuole#GO:0007039;endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein catabolic process#GO:0030163;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nitrogen compound transport#GO:0071705;organonitrogen compound catabolic process#GO:1901565;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization#GO:0045184;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;modification-dependent macromolecule catabolic process#GO:0043632;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;protein localization to vacuole#GO:0072665;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;multivesicular body sorting pathway#GO:0071985;primary metabolic process#GO:0044238;protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;localization#GO:0051179;cellular macromolecule localization#GO:0070727;cellular protein catabolic process#GO:0044257;protein transport#GO:0015031;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=13254|UniProtKB=Q9UET6 Q9UET6 FTSJ1 PTHR10920:SF12 RIBOSOMAL RNA METHYLTRANSFERASE TRNA (CYTIDINE(32)/GUANOSINE(34)-2'-O)-METHYLTRANSFERASE-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;translation#GO:0006412;ncRNA metabolic process#GO:0034660;tRNA methylation#GO:0030488;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;nucleic acid metabolic process#GO:0090304;peptide biosynthetic process#GO:0043043;macromolecule methylation#GO:0043414;methylation#GO:0032259;RNA methylation#GO:0001510;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA methyltransferase#PC00033 HUMAN|HGNC=11777|UniProtKB=P22735 P22735 TGM1 PTHR11590:SF49 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE K transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular protein modification process#GO:0006464 transferase#PC00220 HUMAN|HGNC=16647|UniProtKB=O00574 O00574 CXCR6 PTHR10489:SF705 CELL ADHESION MOLECULE C-X-C CHEMOKINE RECEPTOR TYPE 6 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=22932|UniProtKB=Q9Y5P6 Q9Y5P6 GMPPB PTHR22572:SF15 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE BETA transferase#PC00220 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 HUMAN|HGNC=2896|UniProtKB=P10515 P10515 DLAT PTHR23151:SF9 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED acetyltransferase#PC00038 HUMAN|HGNC=28133|UniProtKB=Q9BTA0 Q9BTA0 FAM167B PTHR32289:SF4 PROTEIN FAM167A PROTEIN FAM167B HUMAN|HGNC=29293|UniProtKB=Q9P227 Q9P227 ARHGAP23 PTHR23175:SF5 FAMILY NOT NAMED RHO GTPASE-ACTIVATING PROTEIN 23 HUMAN|HGNC=14666|UniProtKB=Q8TDU9 Q8TDU9 RXFP4 PTHR24230:SF32 G-PROTEIN COUPLED RECEPTOR RELAXIN-3 RECEPTOR 2 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=9311|UniProtKB=Q13362 Q13362 PPP2R5C PTHR10257:SF19 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;protein autophosphorylation#GO:0046777;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 HUMAN|HGNC=15598|UniProtKB=P81172 P81172 HAMP PTHR16877:SF0 HEPCIDIN HEPCIDIN HUMAN|HGNC=11861|UniProtKB=Q9BZW4 Q9BZW4 TM6SF2 PTHR14568:SF9 TRANSMEMBRANE SUPERFAMILY 6 MEMBER 1/2 TRANSMEMBRANE 6 SUPERFAMILY MEMBER 2 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;lipid metabolic process#GO:0006629;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;regulation of lipid metabolic process#GO:0019216;chemical homeostasis#GO:0048878;regulation of metabolic process#GO:0019222;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=16371|UniProtKB=Q96L46 Q96L46 CAPNS2 PTHR46735:SF4 CALPAIN, SMALL SUBUNIT 1 A-RELATED CALPAIN SMALL SUBUNIT 2 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=10852|UniProtKB=P34897 P34897 SHMT2 PTHR11680:SF53 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL amino acid binding#GO:0016597;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;RNA binding#GO:0003723;translation regulator activity#GO:0045182;transferase activity#GO:0016740;protein homodimerization activity#GO:0042803;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;identical protein binding#GO:0042802;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;transferase activity, transferring one-carbon groups#GO:0016741;ion binding#GO:0043167;anion binding#GO:0043168;organic acid binding#GO:0043177 ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;cellular component biogenesis#GO:0044085;ATP biosynthetic process#GO:0006754;pteridine-containing compound metabolic process#GO:0042558;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;nucleotide biosynthetic process#GO:0009165;carboxylic acid biosynthetic process#GO:0046394;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;alpha-amino acid metabolic process#GO:1901605;purine-containing compound metabolic process#GO:0072521;carboxylic acid catabolic process#GO:0046395;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;purine nucleotide metabolic process#GO:0006163;purine nucleoside triphosphate biosynthetic process#GO:0009145;organic acid biosynthetic process#GO:0016053;cellular component assembly#GO:0022607;oxoacid metabolic process#GO:0043436;purine ribonucleoside triphosphate metabolic process#GO:0009205;cellular amino acid biosynthetic process#GO:0008652;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;pigment metabolic process#GO:0042440;cellular component organization#GO:0016043;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;organic acid metabolic process#GO:0006082;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;purine nucleobase biosynthetic process#GO:0009113;organic acid catabolic process#GO:0016054;ribonucleotide biosynthetic process#GO:0009260;small molecule catabolic process#GO:0044282;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;cellular amino acid metabolic process#GO:0006520;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;regulation of phosphate metabolic process#GO:0019220;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;protein-containing complex assembly#GO:0065003;organonitrogen compound catabolic process#GO:1901565;folic acid-containing compound metabolic process#GO:0006760;cation transport#GO:0006812;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase metabolic process#GO:0009112;cation transmembrane transport#GO:0098655;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;pigment biosynthetic process#GO:0046148;catabolic process#GO:0009056;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular amino acid catabolic process#GO:0009063;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;localization#GO:0051179;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;biological regulation#GO:0065007;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;carboxylic acid metabolic process#GO:0019752;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular amide metabolic process#GO:0043603 envelope#GO:0031975;membrane-enclosed lumen#GO:0031974;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;mitochondrial inner membrane#GO:0005743;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;organelle membrane#GO:0031090;cytosol#GO:0005829;organelle inner membrane#GO:0019866;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;membrane#GO:0016020;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 methyltransferase#PC00155 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 HUMAN|HGNC=23381|UniProtKB=Q9NPH6 Q9NPH6 OBP2B PTHR11430:SF129 LIPOCALIN ODORANT-BINDING PROTEIN 2A-RELATED binding#GO:0005488 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 HUMAN|HGNC=7802|UniProtKB=Q6P4R8 Q6P4R8 NFRKB PTHR13052:SF3 NFRKB-RELATED NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=17361|UniProtKB=Q03989 Q03989 ARID5A PTHR13964:SF25 RBP-RELATED AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=6937|UniProtKB=Q9HCC0 Q9HCC0 MCCC2 PTHR22855:SF13 ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 protein-containing complex#GO:0032991;catalytic complex#GO:1902494 ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 HUMAN|HGNC=386|UniProtKB=P42330 P42330 AKR1C3 PTHR11732:SF494 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;steroid binding#GO:0005496;lipid binding#GO:0008289;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;secondary metabolic process#GO:0019748;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid derivative metabolic process#GO:1901568;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;steroid metabolic process#GO:0008202;fatty acid metabolic process#GO:0006631;organic cyclic compound metabolic process#GO:1901360;unsaturated fatty acid metabolic process#GO:0033559;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 reductase#PC00198 HUMAN|HGNC=8044|UniProtKB=P80303 P80303 NUCB2 PTHR19237:SF22 NUCLEOBINDIN NUCLEOBINDIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 calmodulin-related#PC00061 HUMAN|HGNC=21027|UniProtKB=Q8NFD2 Q8NFD2 ANKK1 PTHR24198:SF175 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN 1 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=10259|UniProtKB=Q92753 Q92753 RORB PTHR45805:SF6 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR ROR-BETA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=25074|UniProtKB=O43325 O43325 LYRM1 PTHR14273:SF0 LYR MOTIF-CONTAINING PROTEIN 1 LYR MOTIF-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5123|UniProtKB=O43248 O43248 HOXC11 PTHR46092:SF1 HOMEOBOX PROTEIN HOX-A11-RELATED HOMEOBOX PROTEIN HOX-C11 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=5137|UniProtKB=P31249 P31249 HOXD3 PTHR45664:SF5 PROTEIN ZERKNUELLT 1-RELATED HOMEOBOX PROTEIN HOX-D3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24174|UniProtKB=Q5FVE4 Q5FVE4 ACSBG2 PTHR24096:SF260 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ACSBG2 ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 long-chain fatty acid metabolic process#GO:0001676;organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 HUMAN|HGNC=28593|UniProtKB=Q8IXS8 Q8IXS8 FAM126B PTHR31220:SF3 HYCCIN RELATED PROTEIN FAM126B protein localization to plasma membrane#GO:0072659;lipid metabolic process#GO:0006629;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;protein localization#GO:0008104;phosphate-containing compound metabolic process#GO:0006796;primary metabolic process#GO:0044238;localization#GO:0051179;protein localization to cell periphery#GO:1990778;glycerolipid metabolic process#GO:0046486;cellular macromolecule localization#GO:0070727;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=10691|UniProtKB=P20132 P20132 SDS PTHR48078:SF8 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED L-SERINE DEHYDRATASE/L-THREONINE DEAMINASE lyase activity#GO:0016829;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 dehydratase#PC00091 HUMAN|HGNC=18141|UniProtKB=Q9UHG0 Q9UHG0 DCDC2 PTHR23004:SF5 DOUBLECORTIN DOMAIN CONTAINING 2 DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 2 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;dendrite development#GO:0016358;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;axoneme assembly#GO:0035082;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;regulation of cellular component biogenesis#GO:0044087;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cilium assembly#GO:0060271;regulation of organelle organization#GO:0033043;localization of cell#GO:0051674;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;cell projection morphogenesis#GO:0048858;amide transport#GO:0042886;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;protein localization to organelle#GO:0033365;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;vesicle localization#GO:0051648;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;dendrite morphogenesis#GO:0048813;cellular component morphogenesis#GO:0032989;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;cell development#GO:0048468;localization#GO:0051179;microtubule-based transport#GO:0099111;cell morphogenesis involved in neuron differentiation#GO:0048667;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;regulation of cell projection assembly#GO:0060491;neuron migration#GO:0001764;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;generation of neurons#GO:0048699;cell migration#GO:0016477 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;actin-based cell projection#GO:0098858;cortical actin cytoskeleton#GO:0030864;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;stereocilium#GO:0032420;non-membrane-bounded organelle#GO:0043228;kinocilium#GO:0060091;stereocilium bundle#GO:0032421;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;cluster of actin-based cell projections#GO:0098862;cortical cytoskeleton#GO:0030863;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;cell cortex#GO:0005938;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;neuron projection#GO:0043005;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=1397|UniProtKB=Q13698 Q13698 CACNA1S PTHR45628:SF9 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1S calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812;calcium ion transport#GO:0006816 voltage-gated ion channel#PC00241 Beta2 adrenergic receptor signaling pathway#P04378>Ca2+ channel#P04445;Beta1 adrenergic receptor signaling pathway#P04377>Ca2+ channel#P04438;Alzheimer disease-amyloid secretase pathway#P00003>L-type calcium channels#P00082;Gonadotropin-releasing hormone receptor pathway#P06664>L-type Ca2+#P06812;Oxytocin receptor mediated signaling pathway#P04391>Ca2+ channel#P04535;5HT2 type receptor mediated signaling pathway#P04374>Ca2+ channel#P04411;Nicotinic acetylcholine receptor signaling pathway#P00044>Ca2+ channel#P01096 HUMAN|HGNC=14126|UniProtKB=A8MWX3 A8MWX3 WASH4P PTHR23331:SF3 CXYORF1 WAS PROTEIN FAMILY HOMOLOG 4-RELATED HUMAN|HGNC=9030|UniProtKB=P04054 P04054 PLA2G1B PTHR11716:SF94 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2 hydrolase activity, acting on ester bonds#GO:0016788;binding#GO:0005488;catalytic activity#GO:0003824;metal ion binding#GO:0046872;phospholipid binding#GO:0005543;signaling receptor binding#GO:0005102;carboxylic ester hydrolase activity#GO:0052689;cation binding#GO:0043169;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;hydrolase activity#GO:0016787;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;phospholipase activity#GO:0004620;anion binding#GO:0043168;ion binding#GO:0043167 lipid metabolic process#GO:0006629;positive regulation of cell population proliferation#GO:0008284;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cell population proliferation#GO:0008283;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;regulation of cell population proliferation#GO:0042127;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 phospholipase#PC00186 HUMAN|HGNC=6667|UniProtKB=P08519 P08519 LPA PTHR24261:SF2 PLASMINOGEN-RELATED APOLIPOPROTEIN(A)-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 Plasminogen activating cascade#P00050>Plasminogen#P01255;Plasminogen activating cascade#P00050>Plasmin#P01246 HUMAN|HGNC=11049|UniProtKB=Q01959 Q01959 SLC6A3 PTHR11616:SF38 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT DOPAMINE TRANSPORTER localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 Dopamine receptor mediated signaling pathway#P05912>DAT#P05962;Adrenaline and noradrenaline biosynthesis#P00001>DAT#P00065;Parkinson disease#P00049>DAT#P01228;Parkinson disease#P00049>DAT#G01547 HUMAN|HGNC=25529|UniProtKB=Q6RFH5 Q6RFH5 WDR74 PTHR16038:SF4 NOP SEVEN ASSOCIATED PROTEIN 1 WD REPEAT-CONTAINING PROTEIN 74 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA processing factor#PC00147 HUMAN|HGNC=1181|UniProtKB=Q9Y2G1 Q9Y2G1 MYRF PTHR13029:SF16 UNCHARACTERIZED MYELIN REGULATORY FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690 positive regulation of gene expression#GO:0010628;membrane organization#GO:0061024;regulation of nitrogen compound metabolic process#GO:0051171;plasma membrane organization#GO:0007009;positive regulation of cellular metabolic process#GO:0031325;endomembrane system organization#GO:0010256;gene expression#GO:0010467;gliogenesis#GO:0042063;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;central nervous system development#GO:0007417;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;oligodendrocyte differentiation#GO:0048709;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;myelination#GO:0042552;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;biosynthetic process#GO:0009058;protein processing#GO:0016485;glial cell differentiation#GO:0010001;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular macromolecule biosynthetic process#GO:2000112 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=227|UniProtKB=Q9NS39 Q9NS39 ADARB2 PTHR10910:SF17 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN DOUBLE-STRANDED RNA-SPECIFIC EDITASE B2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;double-stranded RNA binding#GO:0003725 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=25338|UniProtKB=Q8IYJ0 Q8IYJ0 PIANP PTHR32023:SF2 PILR ALPHA-ASSOCIATED NEURAL PROTEIN PILR ALPHA-ASSOCIATED NEURAL PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=14968|UniProtKB=Q9BXA7 Q9BXA7 TSSK1B PTHR24343:SF76 SERINE/THREONINE KINASE TESTIS-SPECIFIC SERINE/THREONINE-PROTEIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=29405|UniProtKB=Q8IVE0 Q8IVE0 CROCCP3 PTHR23159:SF16 CENTROSOMAL PROTEIN 2 CILIARY ROOTLET COILED-COIL PROTEIN 2-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=4266|UniProtKB=Q02643 Q02643 GHRHR PTHR45620:SF14 PDF RECEPTOR-LIKE PROTEIN-RELATED GROWTH HORMONE-RELEASING HORMONE RECEPTOR signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;growth factor binding#GO:0019838;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;positive regulation of cell population proliferation#GO:0008284;regulation of catalytic activity#GO:0050790;cell population proliferation#GO:0008283;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=1330|UniProtKB=Q9NPC6 Q9NPC6 MYOZ2 PTHR15941:SF9 MYOZENIN MYOZENIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 supramolecular complex#GO:0099080;Z disc#GO:0030018;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;contractile fiber#GO:0043292;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 non-motor actin binding protein#PC00165 HUMAN|HGNC=30076|UniProtKB=Q9BUI4 Q9BUI4 POLR3C PTHR12949:SF0 RNA POLYMERASE III DNA DIRECTED -RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;intracellular#GO:0005622;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;transferase complex#GO:1990234;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=23077|UniProtKB=Q96FW1 Q96FW1 OTUB1 PTHR12931:SF19 UBIQUITIN THIOLESTERASE PROTEIN OTUB UBIQUITIN THIOESTERASE OTUB1 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;ubiquitin-like protein-specific protease activity#GO:0019783;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin binding#GO:0043130;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 DNA repair#GO:0006281;negative regulation of response to DNA damage stimulus#GO:2001021;regulation of double-strand break repair#GO:2000779;regulation of protein modification process#GO:0031399;regulation of response to DNA damage stimulus#GO:2001020;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;regulation of chromatin organization#GO:1902275;histone ubiquitination#GO:0016574;negative regulation of cellular component organization#GO:0051129;cellular protein metabolic process#GO:0044267;negative regulation of DNA metabolic process#GO:0051053;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;protein K48-linked deubiquitination#GO:0071108;histone modification#GO:0016570;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of protein metabolic process#GO:0051248;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;chromosome organization#GO:0051276;negative regulation of protein ubiquitination#GO:0031397;regulation of cellular process#GO:0050794;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;negative regulation of DNA repair#GO:0045738;protein modification process#GO:0036211;regulation of histone modification#GO:0031056;regulation of DNA repair#GO:0006282;organic cyclic compound metabolic process#GO:1901360;negative regulation of organelle organization#GO:0010639;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;histone H2A ubiquitination#GO:0033522;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of double-strand break repair#GO:2000780;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;protein K63-linked ubiquitination#GO:0070534;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=12989|UniProtKB=Q9UBW7 Q9UBW7 ZMYM2 PTHR45736:SF6 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 2 zinc finger transcription factor#PC00244 HUMAN|HGNC=13574|UniProtKB=Q9UBF1 Q9UBF1 MAGEC2 PTHR11736:SF29 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN C2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3087|UniProtKB=Q92997 Q92997 DVL3 PTHR10878:SF6 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-3 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Wnt signaling pathway#P00057>Dishevelled#P01447 HUMAN|HGNC=29326|UniProtKB=Q8TBB6 Q8TBB6 SLC7A14 PTHR43243:SF17 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 amino acid transporter#PC00046 HUMAN|HGNC=12231|UniProtKB=A0A0A6YYG2 A0A0A6YYG2 TRBV6-6 PTHR23268:SF19 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 6-2-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=949|UniProtKB=Q16611 Q16611 BAK1 PTHR11256:SF59 BCL-2 RELATED BCL-2 HOMOLOGOUS ANTAGONIST/KILLER identical protein binding#GO:0042802;protein binding#GO:0005515;protein homodimerization activity#GO:0042803;binding#GO:0005488 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;signaling#GO:0023052 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>Bak#P00275 HUMAN|HGNC=25445|UniProtKB=Q8N3F9 Q8N3F9 GPR137C PTHR15146:SF1 INTEGRAL MEMBRANE PROTEIN GPR137 INTEGRAL MEMBRANE PROTEIN GPR137C regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;TORC1 signaling#GO:0038202;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of intracellular signal transduction#GO:1902531;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of TOR signaling#GO:0032008;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;TOR signaling#GO:0031929 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=6131|UniProtKB=Q00978 Q00978 IRF9 PTHR11949:SF26 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 9 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=18673|UniProtKB=Q96JB5 Q96JB5 CDK5RAP3 PTHR14894:SF2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of mitotic cell cycle#GO:0007346;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=5407|UniProtKB=P09914 P09914 IFIT1 PTHR10271:SF16 INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=37216|UniProtKB=A6NK58 A6NK58 LIPT2 PTHR10993:SF7 OCTANOYLTRANSFERASE LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 transferase#PC00220 Lipoate_biosynthesis#P02750>Lipoyl-protein ligase#P03003 HUMAN|HGNC=4880|UniProtKB=Q9Y5J3 Q9Y5J3 HEY1 PTHR10985:SF78 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY/ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;Notch signaling pathway#GO:0007219 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 HUMAN|HGNC=6484|UniProtKB=Q16363 Q16363 LAMA4 PTHR15036:SF47 PIKACHURIN-LIKE PROTEIN LAMININ SUBUNIT ALPHA-4 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=3368|UniProtKB=O75354 O75354 ENTPD6 PTHR11782:SF99 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 6 nucleotide phosphatase#PC00173 HUMAN|Gene=TRC2L_HUMAN|UniProtKB=Q6ZNB5 Q6ZNB5 - PTHR11370:SF4 DNA-REPAIR PROTEIN XRCC1 XRCC1_N DOMAIN-CONTAINING PROTEIN-RELATED DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=28183|UniProtKB=P0DTE5 P0DTE5 UGT2A2 PTHR48043:SF129 EG:EG0003.4 PROTEIN-RELATED UDP-GLUCURONOSYLTRANSFERASE 2A2 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=33854|UniProtKB=Q569K6 Q569K6 CCDC157 PTHR43696:SF9 COILED-COIL DOMAIN-CONTAINING PROTEIN 157 COILED-COIL DOMAIN-CONTAINING PROTEIN 157 HUMAN|HGNC=28349|UniProtKB=Q96E14 Q96E14 RMI2 PTHR33962:SF1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 RMI2 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 2 DNA repair#GO:0006281;negative regulation of response to DNA damage stimulus#GO:2001021;regulation of double-strand break repair#GO:2000779;regulation of response to DNA damage stimulus#GO:2001020;regulation of chromosome segregation#GO:0051983;regulation of nitrogen compound metabolic process#GO:0051171;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;negative regulation of DNA metabolic process#GO:0051053;organic substance metabolic process#GO:0071704;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of double-strand break repair via homologous recombination#GO:2000042;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;negative regulation of DNA repair#GO:0045738;cell cycle process#GO:0022402;regulation of DNA repair#GO:0006282;regulation of double-strand break repair via homologous recombination#GO:0010569;organic cyclic compound metabolic process#GO:1901360;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;negative regulation of double-strand break repair#GO:2000780;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of DNA recombination#GO:0000018;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=29075|UniProtKB=O60320 O60320 FAM189A1 PTHR17615:SF6 PROTEIN FAM189A PROTEIN FAM189A1 HUMAN|HGNC=11875|UniProtKB=P42166 P42166 TMPO PTHR12019:SF24 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN LAMINA-ASSOCIATED POLYPEPTIDE 2, ISOFORM ALPHA peptide hormone#PC00179 HUMAN|HGNC=28365|UniProtKB=Q5TC79 Q5TC79 ZBTB37 PTHR24399:SF32 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 37 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=31884|UniProtKB=P0C7V7 P0C7V7 SEC11B PTHR10806:SF28 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11B-RELATED hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;signal peptide processing#GO:0006465;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 membrane protein complex#GO:0098796;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 serine protease#PC00203 Endothelin signaling pathway#P00019>signal peptidase#P00573;Vasopressin synthesis#P04395>Signal Peptidase#P04589 HUMAN|HGNC=2571|UniProtKB=P49447 P49447 CYB561 PTHR10106:SF14 CYTOCHROME B561-RELATED CYTOCHROME B561 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 reductase#PC00198 HUMAN|HGNC=3224|UniProtKB=P52798 P52798 EFNA4 PTHR11304:SF42 EPHRIN EPHRIN-A4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=33940|UniProtKB=P0C0P6 P0C0P6 NPS PTHR36679:SF1 NEUROPEPTIDE S NEUROPEPTIDE S HUMAN|HGNC=24255|UniProtKB=Q9Y3B9 Q9Y3B9 RRP15 PTHR13245:SF14 RRP15-LIKE PROTEIN RRP15-LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;rRNA metabolic process#GO:0016072;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;preribosome, large subunit precursor#GO:0030687;protein-containing complex#GO:0032991 HUMAN|HGNC=25527|UniProtKB=Q9H8Y5 Q9H8Y5 ANKZF1 PTHR16036:SF2 ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 HUMAN|HGNC=25852|UniProtKB=Q5T089 Q5T089 MORN1 PTHR23084:SF179 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED MORN REPEAT-CONTAINING PROTEIN 1 kinase#PC00137 HUMAN|HGNC=13721|UniProtKB=Q9Y256 Q9Y256 RCE1 PTHR13046:SF0 PROTEASE U48 CAAX PRENYL PROTEASE RCE1 CAAX PRENYL PROTEASE 2 cysteine-type peptidase activity#GO:0008234;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular process#GO:0009987;protein processing#GO:0016485;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein prenylation#GO:0018342;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=15579|UniProtKB=Q9BZR9 Q9BZR9 TRIM8 PTHR25465:SF19 FAMILY NOT NAMED E3 UBIQUITIN-PROTEIN LIGASE TRIM8 HUMAN|HGNC=1550|UniProtKB=P35520 P35520 CBS PTHR10314:SF8 CYSTATHIONINE BETA-SYNTHASE CYSTATHIONINE BETA-SYNTHASE-RELATED heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159 oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 lyase#PC00144 Cysteine biosynthesis#P02737>O-Acetylserine-lyase#P02887 HUMAN|HGNC=9785|UniProtKB=P51148 P51148 RAB5C PTHR24073:SF366 DRAB5-RELATED RAS-RELATED PROTEIN RAB-5C GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle organization#GO:0016050;regulation of endocytosis#GO:0030100;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 HUMAN|HGNC=3674|UniProtKB=O76093 O76093 FGF18 PTHR11486:SF4 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 18 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=664|UniProtKB=P78540 P78540 ARG2 PTHR43782:SF4 ARGINASE ARGINASE-2, MITOCHONDRIAL cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;arginine catabolic process#GO:0006527;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 hydrolase#PC00121 HUMAN|HGNC=10720|UniProtKB=P14151 P14151 SELL PTHR19325:SF543 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING L-SELECTIN HUMAN|HGNC=1609|UniProtKB=P51685 P51685 CCR8 PTHR10489:SF627 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 8 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=17318|UniProtKB=Q8WXD0 Q8WXD0 RXFP2 PTHR24372:SF72 GLYCOPROTEIN HORMONE RECEPTOR RELAXIN RECEPTOR 2 signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=31371|UniProtKB=Q6PRD1 Q6PRD1 GPR179 PTHR32546:SF7 G-PROTEIN COUPLED RECEPTOR 158-RELATED G-PROTEIN COUPLED RECEPTOR 179-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=441|UniProtKB=P10696 P10696 ALPG PTHR11596:SF81 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE, GERM CELL TYPE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;dephosphorylation#GO:0016311 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=19950|UniProtKB=Q8NG50 Q8NG50 RDM1 PTHR31164:SF1 RAD52 MOTIF-CONTAINING PROTEIN 1 RAD52 MOTIF-CONTAINING PROTEIN 1 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=24279|UniProtKB=Q9BZJ4 Q9BZJ4 SLC25A39 PTHR45760:SF1 FI19922P1-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 39 HUMAN|HGNC=26902|UniProtKB=Q8NC24 Q8NC24 RELL2 PTHR31481:SF0 RELT-LIKE PROTEIN 2 RELL2 RELT-LIKE PROTEIN 2 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;positive regulation of cell-substrate adhesion#GO:0010811;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;biological adhesion#GO:0022610;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;regulation of cell adhesion#GO:0030155;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;regulation of stress-activated MAPK cascade#GO:0032872;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cell adhesion#GO:0045785;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 HUMAN|HGNC=11460|UniProtKB=P51687 P51687 SUOX PTHR19372:SF7 SULFITE REDUCTASE SULFITE OXIDASE, MITOCHONDRIAL reductase#PC00198 HUMAN|HGNC=3271|UniProtKB=Q14152 Q14152 EIF3A PTHR14005:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=32467|UniProtKB=B4DX44 B4DX44 ZNF736 PTHR24384:SF98 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 736 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=18121|UniProtKB=Q9BY79 Q9BY79 MFRP PTHR22923:SF108 CEREBELLIN-RELATED MEMBRANE FRIZZLED-RELATED PROTEIN HUMAN|HGNC=13607|UniProtKB=Q9UKB1 Q9UKB1 FBXW11 PTHR44129:SF4 WD REPEAT-CONTAINING PROTEIN POP1 F-BOX/WD REPEAT-CONTAINING PROTEIN 11 Hedgehog signaling pathway#P00025>Slimb#P00683;Parkinson disease#P00049>hSel10#P01240;Wnt signaling pathway#P00057>betaTrCP#P01454 HUMAN|HGNC=15297|UniProtKB=Q8NGG3 Q8NGG3 OR5T3 PTHR24247:SF87 5-HYDROXYTRYPTAMINE RECEPTOR OLFACTORY RECEPTOR 5T3 cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;organic cyclic compound binding#GO:0097159;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;neurotransmitter receptor activity#GO:0030594;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cell-cell signaling#GO:0007267;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;dendrite#GO:0030425;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=28055|UniProtKB=Q86UD0 Q86UD0 SAPCD2 PTHR14907:SF3 FI14130P SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=14792|UniProtKB=P0C7T3 P0C7T3 OR56A5 PTHR24248:SF110 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 56A4-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=21108|UniProtKB=Q5JS54 Q5JS54 PSMG4 PTHR33559:SF1 PROTEASOME ASSEMBLY CHAPERONE 4 PROTEASOME ASSEMBLY CHAPERONE 4 chaperone#PC00072 HUMAN|HGNC=29819|UniProtKB=Q9ULH7 Q9ULH7 MRTFB PTHR22793:SF5 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN-RELATED TRANSCRIPTION FACTOR B muscle structure development#GO:0061061;cellular developmental process#GO:0048869;cell differentiation#GO:0030154;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;anatomical structure development#GO:0048856;developmental process#GO:0032502 DNA-binding transcription factor#PC00218 HUMAN|HGNC=14289|UniProtKB=Q9NZ94 Q9NZ94 NLGN3 PTHR43903:SF4 NEUROLIGIN NEUROLIGIN-3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;transport#GO:0006810;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;vesicle organization#GO:0016050;cell junction assembly#GO:0034329;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;endocytosis#GO:0006897;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;vesicle budding from membrane#GO:0006900;synapse assembly#GO:0007416;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;vesicle-mediated transport in synapse#GO:0099003 cell surface#GO:0009986;synapse#GO:0045202;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;cell junction#GO:0030054;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=33241|UniProtKB=P0CG31 P0CG31 ZNF286B PTHR24377:SF217 IP01015P-RELATED ZINC FINGER PROTEIN 286A-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19356|UniProtKB=Q9P299 Q9P299 COPZ2 PTHR11043:SF4 ZETA-COAT PROTEIN COATOMER SUBUNIT ZETA-2 cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;COPI vesicle coat#GO:0030126;membrane coat#GO:0030117;intracellular#GO:0005622;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;plasma membrane#GO:0005886 vesicle coat protein#PC00235 HUMAN|HGNC=14372|UniProtKB=Q96KG9 Q96KG9 SCYL1 PTHR12984:SF3 SCY1-RELATED S/T PROTEIN KINASE-LIKE N-TERMINAL KINASE-LIKE PROTEIN non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=12441|UniProtKB=P04818 P04818 TYMS PTHR11548:SF2 THYMIDYLATE SYNTHASE 1 THYMIDYLATE SYNTHASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;pyrimidine nucleotide biosynthetic process#GO:0006221;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 methyltransferase#PC00155 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>Thymidylate synthase#P02913;Formyltetrahydroformate biosynthesis#P02743>Thymidylate synthase#P02954;Formyltetrahydroformate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 HUMAN|HGNC=21661|UniProtKB=Q5SSG8 Q5SSG8 MUC21 PTHR39408:SF3 MUCIN-21 MUCIN-21 HUMAN|HGNC=16989|UniProtKB=Q9UBU8 Q9UBU8 MORF4L1 PTHR10880:SF29 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;histone H4 acetylation#GO:0043967;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;peptidyl-lysine acetylation#GO:0018394;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;chromatin silencing#GO:0006342;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=28565|UniProtKB=Q8N4B4 Q8N4B4 FBXO39 PTHR10706:SF130 F-BOX FAMILY PROTEIN F-BOX ONLY PROTEIN 39 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=23142|UniProtKB=Q17RD7 Q17RD7 SYT16 PTHR46129:SF4 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN-16 HUMAN|HGNC=32415|UniProtKB=P0DJD1 P0DJD1 RGPD2 PTHR23138:SF87 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=30004|UniProtKB=P0DMN0 P0DMN0 SULT1A4 PTHR11783:SF44 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1A3-RELATED transferase#PC00220 HUMAN|HGNC=225|UniProtKB=P55265 P55265 ADAR PTHR10910:SF107 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN DOUBLE-STRANDED RNA-SPECIFIC ADENOSINE DEAMINASE nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;double-stranded RNA binding#GO:0003725 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=696|UniProtKB=Q9Y689 Q9Y689 ARL5A PTHR11711:SF147 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5A carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 G-protein#PC00020 HUMAN|HGNC=4262|UniProtKB=P01242 P01242 GH2 PTHR11417:SF40 SOMATOTROPIN,PROLACTIN GROWTH HORMONE VARIANT receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;response to extracellular stimulus#GO:0009991;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to hormone stimulus#GO:0032870;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;positive regulation of receptor signaling pathway via STAT#GO:1904894;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of growth#GO:0045927;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;tyrosine phosphorylation of STAT protein#GO:0007260;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to peptide hormone#GO:0043434;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;growth#GO:0040007;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of growth#GO:0040008;regulation of receptor signaling pathway via STAT#GO:1904892;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;response to peptide#GO:1901652;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;response to nutrient levels#GO:0031667;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to hormone#GO:0009725;receptor signaling pathway via STAT#GO:0097696;peptidyl-tyrosine modification#GO:0018212;regulation of macromolecule metabolic process#GO:0060255;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 HUMAN|HGNC=10495|UniProtKB=P33763 P33763 S100A5 PTHR11639:SF65 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A5 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 calmodulin-related#PC00061 HUMAN|HGNC=13192|UniProtKB=Q99543 Q99543 DNAJC2 PTHR43999:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 chaperone#PC00072 HUMAN|HGNC=18475|UniProtKB=Q9Y397 Q9Y397 ZDHHC9 PTHR22883:SF71 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC9 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=17294|UniProtKB=Q5VWQ8 Q5VWQ8 DAB2IP PTHR10194:SF26 RAS GTPASE-ACTIVATING PROTEINS DISABLED HOMOLOG 2-INTERACTING PROTEIN GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 HUMAN|HGNC=9776|UniProtKB=P57729 P57729 RAB38 PTHR24073:SF839 DRAB5-RELATED RAS-RELATED PROTEIN RAB-38 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;pigmentation#GO:0043473;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;melanosome organization#GO:0032438;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;mitochondrion#GO:0005739;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=28068|UniProtKB=Q86T29 Q86T29 ZNF605 PTHR24377:SF120 IP01015P-RELATED ZINC FINGER PROTEIN 605 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2206|UniProtKB=P53420 P53420 COL4A4 PTHR24023:SF714 COLLAGEN ALPHA COLLAGEN ALPHA-4(IV) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;basement membrane#GO:0005604;extracellular region#GO:0005576;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;supramolecular polymer#GO:0099081 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=30033|UniProtKB=Q9NRX4 Q9NRX4 PHPT1 PTHR12258:SF10 JANUS-A/JANUS-B 14 KDA PHOSPHOHISTIDINE PHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2280|UniProtKB=P14854 P14854 COX6B1 PTHR11387:SF16 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B1 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidase#PC00175 HUMAN|HGNC=28930|UniProtKB=Q5XKE5 Q5XKE5 KRT79 PTHR45616:SF10 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 79 HUMAN|HGNC=33529|UniProtKB=C9JA33 C9JA33 PALM2AKAP2 PTHR10498:SF10 PARALEMMIN-RELATED A-KINASE ANCHOR PROTEIN 2-RELATED HUMAN|HGNC=1775|UniProtKB=Q15078 Q15078 CDK5R1 PTHR23401:SF2 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 1 kinase activator#PC00138 HUMAN|HGNC=11765|UniProtKB=P01135 P01135 TGFA PTHR10740:SF1 TRANSFORMING GROWTH FACTOR ALPHA PROTRANSFORMING GROWTH FACTOR ALPHA regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of mitotic nuclear division#GO:0007088;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;nuclear division#GO:0000280;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;mitotic cell cycle#GO:0000278;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of mitotic cell cycle#GO:0045931;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of organelle organization#GO:0033043;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;cell cycle process#GO:0022402;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of cell cycle process#GO:0090068;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of nuclear division#GO:0051783;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of mitotic nuclear division#GO:0045840;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of protein serine/threonine kinase activity#GO:0071902;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of mitotic cell cycle#GO:0007346 growth factor#PC00112 EGF receptor signaling pathway#P00018>EGF#P00549 HUMAN|HGNC=20324|UniProtKB=O95455 O95455 TGDS PTHR43000:SF7 DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED DTDP-D-GLUCOSE 4,6-DEHYDRATASE dehydratase#PC00091 O-antigen biosynthesis#P02757>dTDP-glucose 4,6-dehydratase#P03045 HUMAN|HGNC=23053|UniProtKB=Q86UN3 Q86UN3 RTN4RL2 PTHR24373:SF272 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN RETICULON-4 RECEPTOR-LIKE 2 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=3316|UniProtKB=P32519 P32519 ELF1 PTHR11849:SF156 ETS ETS-RELATED TRANSCRIPTION FACTOR ELF-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=16435|UniProtKB=Q8TCT9 Q8TCT9 HM13 PTHR12174:SF23 SIGNAL PEPTIDE PEPTIDASE MINOR HISTOCOMPATIBILITY ANTIGEN H13 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;signal peptide processing#GO:0006465;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 leaflet of membrane bilayer#GO:0097478;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;side of membrane#GO:0098552;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum membrane#GO:0005789 aspartic protease#PC00053 HUMAN|HGNC=37325|UniProtKB=E5RG02 E5RG02 PRSS46P PTHR24256:SF205 TRYPTASE-RELATED SERINE PROTEASE 46-RELATED serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=633|UniProtKB=P29972 P29972 AQP1 PTHR19139:SF161 AQUAPORIN TRANSPORTER AQUAPORIN-1 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 transmembrane transport#GO:0055085;transport#GO:0006810;system process#GO:0003008;regulation of body fluid levels#GO:0050878;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;localization#GO:0051179;response to stimulus#GO:0050896;organic substance transport#GO:0071702;multicellular organismal homeostasis#GO:0048871;response to stress#GO:0006950;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;response to osmotic stress#GO:0006970;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=20675|UniProtKB=Q96KN2 Q96KN2 CNDP1 PTHR43270:SF1 BETA-ALA-HIS DIPEPTIDASE BETA-ALA-HIS DIPEPTIDASE hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=12311|UniProtKB=Q15654 Q15654 TRIP6 PTHR24212:SF7 ZYXIN/TRIP6 THYROID RECEPTOR-INTERACTING PROTEIN 6 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of NIK/NF-kappaB signaling#GO:1901222;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;positive regulation of NIK/NF-kappaB signaling#GO:1901224;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;NIK/NF-kappaB signaling#GO:0038061;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;anchoring junction#GO:0070161;cell junction#GO:0030054;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=41985|UniProtKB=C9JG80 C9JG80 NPIPB4 PTHR15438:SF5 NUCLEAR PORE COMPLEX INTERACTING PROTEIN NUCLEAR PORE COMPLEX-INTERACTING PROTEIN FAMILY MEMBER B11-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=2740|UniProtKB=Q92841 Q92841 DDX17 PTHR47958:SF140 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX17-RELATED catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;alternative mRNA splicing, via spliceosome#GO:0000380;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16644|UniProtKB=A6NNB3 A6NNB3 IFITM5 PTHR13999:SF10 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 5 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=25204|UniProtKB=Q2NL68 Q2NL68 PROSER3 PTHR22045:SF6 PROLINE AND SERINE-RICH PROTEIN 3 PROLINE AND SERINE-RICH PROTEIN 3 HUMAN|HGNC=4218|UniProtKB=Q9NR23 Q9NR23 GDF3 PTHR11848:SF38 TGF-BETA FAMILY GROWTH/DIFFERENTIATION FACTOR 3 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=13919|UniProtKB=P46379 P46379 BAG6 PTHR15204:SF0 LARGE PROLINE-RICH PROTEIN BAG6 LARGE PROLINE-RICH PROTEIN BAG6 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=11811|UniProtKB=O14901 O14901 KLF11 PTHR23235:SF65 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 11 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29022|UniProtKB=Q69YQ0 Q69YQ0 SPECC1L PTHR23167:SF18 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED CYTOSPIN-A cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856 HUMAN|HGNC=3748|UniProtKB=P20930 P20930 FLG PTHR22571:SF49 FILAGGRIN-RELATED FILAGGRIN system development#GO:0048731;multicellular organismal homeostasis#GO:0048871;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of body fluid levels#GO:0050878;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;skin development#GO:0043588 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=21697|UniProtKB=Q9BXJ8 Q9BXJ8 TMEM120A PTHR21433:SF1 TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA ION CHANNEL TACAN cellular developmental process#GO:0048869;cell differentiation#GO:0030154;fat cell differentiation#GO:0045444;cellular process#GO:0009987;developmental process#GO:0032502 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=16489|UniProtKB=Q8WYN0 Q8WYN0 ATG4A PTHR22624:SF35 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE ATG4A cysteine protease#PC00081 HUMAN|HGNC=8819|UniProtKB=O00764 O00764 PDXK PTHR10534:SF2 PYRIDOXAL KINASE PYRIDOXAL KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;heterocycle biosynthetic process#GO:0018130;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 kinase#PC00137 Vitamin B6 metabolism#P02787>Pyridoxal kinase#P03244;Pyridoxal phosphate salvage pathway#P02770>Pyridoxal kinase#P03121;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine kinase#P03122 HUMAN|HGNC=5006|UniProtKB=P04035 P04035 HMGCR PTHR10572:SF24 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE reductase#PC00198 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA reductase#P00491 HUMAN|HGNC=23219|UniProtKB=Q58DX5 Q58DX5 NAALADL2 PTHR10404:SF32 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE INACTIVE N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE-LIKE PROTEIN 2 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153 HUMAN|HGNC=23247|UniProtKB=Q4LDG9 Q4LDG9 DNAL1 PTHR15454:SF33 NISCHARIN RELATED DYNEIN LIGHT CHAIN 1, AXONEMAL enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28063|UniProtKB=Q5HY98 Q5HY98 ZNF766 PTHR24407:SF10 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 766 HUMAN|HGNC=9796|UniProtKB=P53611 P53611 RABGGTB PTHR11774:SF11 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein prenylation#GO:0018342;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 acyltransferase#PC00042 HUMAN|HGNC=23329|UniProtKB=Q8TF47 Q8TF47 ZFP90 PTHR24381:SF143 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 90 HOMOLOG DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28910|UniProtKB=Q96HB5 Q96HB5 CCDC120 PTHR16093:SF5 COILED-COIL DOMAIN-CONTAINING PROTEIN 120 FAMILY MEMBER COILED-COIL DOMAIN-CONTAINING PROTEIN 120 HUMAN|HGNC=21329|UniProtKB=Q86UN2 Q86UN2 RTN4RL1 PTHR24373:SF274 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN RETICULON-4 RECEPTOR-LIKE 1 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=7091|UniProtKB=Q29980 Q29980 MICB PTHR16675:SF154 MHC CLASS I-RELATED MHC CLASS I POLYPEPTIDE-RELATED SEQUENCE A-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=11024|UniProtKB=P57057 P57057 SLC37A1 PTHR43184:SF11 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A1 carbohydrate derivative transmembrane transporter activity#GO:1901505;secondary active transmembrane transporter activity#GO:0015291;inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;anion:anion antiporter activity#GO:0015301;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;organophosphate ester transmembrane transporter activity#GO:0015605;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 organophosphate ester transport#GO:0015748;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;anion transport#GO:0006820;carbohydrate derivative transport#GO:1901264;inorganic anion transport#GO:0015698 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=1514|UniProtKB=P41180 P41180 CASR PTHR24061:SF358 CALCIUM-SENSING RECEPTOR-RELATED EXTRACELLULAR CALCIUM-SENSING RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;transmembrane signaling receptor activity#GO:0004888 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of metal ion transport#GO:0010959;transport#GO:0006810;regulation of localization#GO:0032879;cation transport#GO:0006812;cellular homeostasis#GO:0019725;detection of chemical stimulus#GO:0009593;calcium ion transport#GO:0006816;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;response to inorganic substance#GO:0010035;ion transport#GO:0006811;homeostatic process#GO:0042592;detection of stimulus#GO:0051606;regulation of calcium ion transport#GO:0051924;response to metal ion#GO:0010038;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=26756|UniProtKB=Q6UWP7 Q6UWP7 LCLAT1 PTHR10983:SF59 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED LYSOCARDIOLIPIN ACYLTRANSFERASE 1 transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=9495|UniProtKB=P24158 P24158 PRTN3 PTHR24257:SF15 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER MYELOBLASTIN serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 localization#GO:0051179;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;phagocytosis#GO:0006909;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;transport#GO:0006810;organonitrogen compound metabolic process#GO:1901564;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=1765|UniProtKB=P55285 P55285 CDH6 PTHR24027:SF322 CADHERIN-23 CADHERIN-6 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=25180|UniProtKB=Q0JRZ9 Q0JRZ9 FCHO2 PTHR23065:SF8 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 F-BAR DOMAIN ONLY PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;cellular protein-containing complex assembly#GO:0034622;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;protein-containing complex subunit organization#GO:0043933;vesicle-mediated transport in synapse#GO:0099003 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=5056|UniProtKB=P31314 P31314 TLX1 PTHR45921:SF2 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=5429|UniProtKB=P32881 P32881 IFNA8 PTHR11691:SF28 TYPE I INTERFERON INTERFERON ALPHA-8 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=25731|UniProtKB=Q3ZCT8 Q3ZCT8 KBTBD12 PTHR24412:SF459 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 12 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26352|UniProtKB=Q8IYW4 Q8IYW4 ENTHD1 PTHR12276:SF57 EPSIN/ENT-RELATED ENTH DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 HUMAN|HGNC=13427|UniProtKB=Q6XE24 Q6XE24 RBMS3 PTHR24012:SF742 RNA BINDING PROTEIN RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 3 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29559|UniProtKB=Q96GC9 Q96GC9 VMP1 PTHR10281:SF1 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED VACUOLE MEMBRANE PROTEIN 1 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=25719|UniProtKB=Q96C57 Q96C57 CUSTOS PTHR14482:SF0 CHROMOSOME 12 ORF 43 HOMOLOG PROTEIN CUSTOS HUMAN|HGNC=838|UniProtKB=P56381 P56381 ATP5F1E PTHR12448:SF1 ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL ATP SYNTHASE SUBUNIT EPSILON, MITOCHONDRIAL pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002 HUMAN|HGNC=18345|UniProtKB=Q96IP4 Q96IP4 TENT5A PTHR12974:SF25 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 TERMINAL NUCLEOTIDYLTRANSFERASE 5A adenylyltransferase activity#GO:0070566;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;negative regulation of cellular catabolic process#GO:0031330;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265 HUMAN|HGNC=1176|UniProtKB=Q13405 Q13405 MRPL49 PTHR13477:SF0 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49 39S RIBOSOMAL PROTEIN L49, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=6436|UniProtKB=P08727 P08727 KRT19 PTHR23239:SF14 INTERMEDIATE FILAMENT KERATIN, TYPE I CYTOSKELETAL 19 HUMAN|HGNC=5522|UniProtKB=P01854 P01854 IGHE PTHR23266:SF90 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY CONSTANT EPSILON protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=10466|UniProtKB=Q9BST9 Q9BST9 RTKN PTHR21538:SF19 ANILLIN/RHOTEKIN RTKN RHOTEKIN Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;GTP-Rho binding#GO:0017049;Rho GTPase binding#GO:0017048 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell division#GO:0051301;actomyosin contractile ring organization#GO:0044837;membrane fission#GO:0090148;assembly of actomyosin apparatus involved in cytokinesis#GO:0000912;membrane organization#GO:0061024;septin ring organization#GO:0031106;actomyosin contractile ring assembly#GO:0000915;nuclear division#GO:0000280;cell cycle process#GO:0022402;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cellular process#GO:0009987;cytokinetic process#GO:0032506;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cytokinesis#GO:0000910;cortical actin cytoskeleton organization#GO:0030866;septin cytoskeleton organization#GO:0032185 actomyosin contractile ring#GO:0005826;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cell division site#GO:0032153;contractile ring#GO:0070938;cytoskeleton#GO:0005856 non-motor actin binding protein#PC00165 HUMAN|HGNC=2183|UniProtKB=Q7Z7G8 Q7Z7G8 VPS13B PTHR12517:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B membrane traffic protein#PC00150 HUMAN|HGNC=26638|UniProtKB=Q6NVH7 Q6NVH7 SWSAP1 PTHR28653:SF1 FAMILY NOT NAMED ATPASE SWSAP1 HUMAN|HGNC=705|UniProtKB=O15144 O15144 ARPC2 PTHR12058:SF0 ARP2/3 COMPLEX 34 KDA SUBUNIT ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;structural molecule activity#GO:0005198;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;Arp2/3 protein complex#GO:0005885;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 Integrin signalling pathway#P00034>Arp2/3#P00912;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 HUMAN|HGNC=33437|UniProtKB=P0CG30 P0CG30 GSTT2B PTHR43917:SF4 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE THETA-2-RELATED transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=3771|UniProtKB=P31513 P31513 FMO3 PTHR23023:SF44 DIMETHYLANILINE MONOOXYGENASE DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 oxygenase#PC00177 Nicotine degradation#P05914>FMO3#P05979 HUMAN|HGNC=32363|UniProtKB=Q8WUX2 Q8WUX2 CHAC2 PTHR12192:SF2 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2 lyase activity#GO:0016829;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=48576|UniProtKB=A0A1B0GWG4 A0A1B0GWG4 SERTM2 PTHR35660:SF2 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING 2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=21173|UniProtKB=Q96GA3 Q96GA3 LTV1 PTHR21531:SF0 LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED PROTEIN LTV1 HOMOLOG cellular component biogenesis#GO:0044085;ribosomal subunit export from nucleus#GO:0000054;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;ribosome biogenesis#GO:0042254;establishment of organelle localization#GO:0051656;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;peptide transport#GO:0015833;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;ribonucleoprotein complex biogenesis#GO:0022613;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;ribosomal small subunit biogenesis#GO:0042274;protein-containing complex localization#GO:0031503 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;preribosome, small subunit precursor#GO:0030688;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;preribosome#GO:0030684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=8636|UniProtKB=P11498 P11498 PC PTHR43778:SF2 PYRUVATE CARBOXYLASE PYRUVATE CARBOXYLASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;cellular metabolic process#GO:0044237;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;glucose metabolic process#GO:0006006;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 Pyruvate metabolism#P02772>Pyruvate Carboxylase#P03140 HUMAN|HGNC=11908|UniProtKB=Q9Y6Q6 Q9Y6Q6 TNFRSF11A PTHR47134:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11A TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;tumor necrosis factor binding#GO:0043120;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;cytokine binding#GO:0019955 response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;tissue remodeling#GO:0048771;osteoclast differentiation#GO:0030316;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;bone remodeling#GO:0046849;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of tissue remodeling#GO:0034103;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;ossification#GO:0001503;immune system development#GO:0002520;tumor necrosis factor-mediated signaling pathway#GO:0033209;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to tumor necrosis factor#GO:0034612;nucleobase-containing compound biosynthetic process#GO:0034654;multicellular organismal homeostasis#GO:0048871;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;response to interleukin-1#GO:0070555;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of bone remodeling#GO:0046850;cellular response to tumor necrosis factor#GO:0071356;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;tissue homeostasis#GO:0001894;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;bone resorption#GO:0045453;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;signaling#GO:0023052;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;response to organic substance#GO:0010033;myeloid cell differentiation#GO:0030099;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of DNA-binding transcription factor activity#GO:0051090;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;regulation of bone resorption#GO:0045124;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=17044|UniProtKB=Q8N8Q9 Q8N8Q9 NIPA2 PTHR12570:SF1 UNCHARACTERIZED MAGNESIUM TRANSPORTER NIPA2 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812 cellular anatomical entity#GO:0110165;membrane#GO:0016020 Huntington disease#P00029>p53#P00797 HUMAN|HGNC=16977|UniProtKB=Q9UBK5 Q9UBK5 HCST PTHR21409:SF1 HEMATOPOIETIC CELL SIGNAL TRANSDUCER HEMATOPOIETIC CELL SIGNAL TRANSDUCER HUMAN|HGNC=18018|UniProtKB=Q8IX18 Q8IX18 DHX40 PTHR18934:SF234 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX40-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA helicase#PC00032 HUMAN|HGNC=21253|UniProtKB=Q8TAF8 Q8TAF8 LHFPL5 PTHR12489:SF18 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 5 PROTEIN response to stimulus#GO:0050896;response to external stimulus#GO:0009605;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;sensory perception of sound#GO:0007605;system process#GO:0003008;multicellular organismal process#GO:0032501;detection of stimulus#GO:0051606;nervous system process#GO:0050877;sensory perception#GO:0007600;response to abiotic stimulus#GO:0009628 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=29623|UniProtKB=Q9Y2E5 Q9Y2E5 MAN2B2 PTHR11607:SF28 ALPHA-MANNOSIDASE EPIDIDYMIS-SPECIFIC ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;whole membrane#GO:0098805 HUMAN|HGNC=11740|UniProtKB=P02787 P02787 TF PTHR11485:SF31 TRANSFERRIN SEROTRANSFERRIN response to external biotic stimulus#GO:0043207;metal ion transport#GO:0030001;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;localization#GO:0051179;defense response to bacterium#GO:0042742;antibacterial humoral response#GO:0019731;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;antimicrobial humoral response#GO:0019730;defense response to other organism#GO:0098542;establishment of localization#GO:0051234;response to other organism#GO:0051707;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;defense response#GO:0006952 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;early endosome#GO:0005769;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 HUMAN|HGNC=26508|UniProtKB=Q2TBE0 Q2TBE0 CWF19L2 PTHR12072:SF5 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682 HUMAN|HGNC=34350|UniProtKB=A6NN90 A6NN90 C2orf81 PTHR34438:SF1 SI:DKEY-97L20.6 SI:DKEY-97L20.6 HUMAN|HGNC=991|UniProtKB=Q16548 Q16548 BCL2A1 PTHR11256:SF10 BCL-2 RELATED BCL-2-RELATED PROTEIN A1 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;protein homodimerization activity#GO:0042803;binding#GO:0005488;identical protein binding#GO:0042802;protein binding#GO:0005515;channel activity#GO:0015267;transporter activity#GO:0005215 mitochondrial fusion#GO:0008053;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;signal transduction#GO:0007165;apoptotic mitochondrial changes#GO:0008637;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;apoptotic process#GO:0006915;cell death#GO:0008219;mitochondrion organization#GO:0007005;intracellular signal transduction#GO:0035556;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organelle fusion#GO:0048284;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cellular response to stress#GO:0033554;positive regulation of cell death#GO:0010942 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>A1#P00283 HUMAN|HGNC=29316|UniProtKB=Q9HCJ5 Q9HCJ5 ZSWIM6 PTHR22619:SF3 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 6 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;regulation of locomotion#GO:0040012;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;regulation of chemotaxis#GO:0050920;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;regulation of response to external stimulus#GO:0032101;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;generation of neurons#GO:0048699 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234 HUMAN|HGNC=20870|UniProtKB=Q9H7B2 Q9H7B2 RPF2 PTHR12728:SF0 BRIX DOMAIN CONTAINING PROTEIN RIBOSOME PRODUCTION FACTOR 2 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosomal large subunit assembly#GO:0000027;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of LSU-rRNA#GO:0000470 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28637|UniProtKB=Q96II8 Q96II8 LRCH3 PTHR16083:SF7 LEUCINE RICH REPEAT CONTAINING PROTEIN DISP COMPLEX PROTEIN LRCH3 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=10892|UniProtKB=O95475 O95475 SIX6 PTHR10390:SF12 HOMEOBOX PROTEIN SIX HOMEOBOX PROTEIN SIX6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;visual system development#GO:0150063;sensory system development#GO:0048880;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;eye development#GO:0001654;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;sensory organ development#GO:0007423;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 HUMAN|HGNC=2992|UniProtKB=O77932 O77932 DXO PTHR12395:SF9 DOM-3 RELATED DECAPPING AND EXORIBONUCLEASE PROTEIN pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11333|UniProtKB=P31391 P31391 SSTR4 PTHR24229:SF35 NEUROPEPTIDES RECEPTOR SOMATOSTATIN RECEPTOR TYPE 4 neuropeptide binding#GO:0042923;signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cellular response to steroid hormone stimulus#GO:0071383;response to lipid#GO:0033993;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;response to steroid hormone#GO:0048545 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=7121|UniProtKB=Q9NXB0 Q9NXB0 MKS1 PTHR12968:SF4 B9 DOMAIN-CONTAINING MECKEL SYNDROME TYPE 1 PROTEIN vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;ciliary transition zone#GO:0035869;plasma membrane#GO:0005886 structural protein#PC00211 HUMAN|HGNC=4806|UniProtKB=P42357 P42357 HAL PTHR10362:SF7 HISTIDINE AMMONIA-LYASE HISTIDINE AMMONIA-LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 lyase#PC00144 HUMAN|HGNC=11623|UniProtKB=Q99081 Q99081 TCF12 PTHR11793:SF11 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR 12 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=2600|UniProtKB=P08686 P08686 CYP21A2 PTHR24281:SF155 STEROID 21-HYDROXYLASE-RELATED STEROID 21-HYDROXYLASE hydroxylase#PC00122 HUMAN|HGNC=28448|UniProtKB=Q8N661 Q8N661 TMEM86B PTHR31885:SF7 GH04784P LYSOPLASMALOGENASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824 HUMAN|HGNC=14675|UniProtKB=P78412 P78412 IRX6 PTHR11211:SF11 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=9864|UniProtKB=P10276 P10276 RARA PTHR24082:SF115 NUCLEAR HORMONE RECEPTOR RETINOIC ACID RECEPTOR ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 Vitamin D metabolism and pathway#P04396>RXR#P04602 HUMAN|HGNC=10020|UniProtKB=O43353 O43353 RIPK2 PTHR44329:SF9 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of JNK cascade#GO:0046330;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;positive regulation of protein serine/threonine kinase activity#GO:0071902;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=26516|UniProtKB=Q6P9G0 Q6P9G0 CYB5D1 PTHR21281:SF0 UNCHARACTERIZED CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=4627|UniProtKB=P09210 P09210 GSTA2 PTHR11571:SF107 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE A2 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 cellular response to stimulus#GO:0051716;sulfur compound metabolic process#GO:0006790;cellular response to chemical stimulus#GO:0070887;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;response to stimulus#GO:0050896;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=1786|UniProtKB=P49918 P49918 CDKN1C PTHR10265:SF44 CYCLIN-DEPENDENT KINASE INHIBITOR 1 CYCLIN-DEPENDENT KINASE INHIBITOR 1C kinase inhibitor#PC00139 HUMAN|HGNC=1758|UniProtKB=Q9H159 Q9H159 CDH19 PTHR24027:SF323 CADHERIN-23 CADHERIN-19 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=19578|UniProtKB=Q8N349 Q8N349 OR2L13 PTHR26453:SF102 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2L13 transmembrane signal receptor#PC00197 HUMAN|HGNC=25483|UniProtKB=Q9BSJ6 Q9BSJ6 PIMREG PTHR35819:SF1 PICALM INTERACTING MITOTIC REGULATOR PIMREG PROTEIN PIMREG HUMAN|HGNC=10970|UniProtKB=Q4U2R8 Q4U2R8 SLC22A6 PTHR24064:SF294 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 6 secondary carrier transporter#PC00258 HUMAN|HGNC=18125|UniProtKB=Q96A05 Q96A05 ATP6V1E2 PTHR45715:SF7 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED V-TYPE PROTON ATPASE SUBUNIT E 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 HUMAN|HGNC=30203|UniProtKB=Q9Y284 Q9Y284 WDR83OS PTHR13193:SF0 CGI-140 PROTEIN ASTERIX HUMAN|HGNC=51513|UniProtKB=A0A669KB04 A0A669KB04 SPDYE17 PTHR31156:SF15 WBSCR19-LIKE PROTEIN SPEEDY PROTEIN E2-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 HUMAN|HGNC=2810|UniProtKB=O60443 O60443 GSDME PTHR15207:SF1 NONSYNDROMIC HEARING IMPAIRMENT PROTEIN GASDERMIN-E HUMAN|HGNC=28430|UniProtKB=Q9BV81 Q9BV81 EMC6 PTHR20994:SF0 UNCHARACTERIZED ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;protein folding#GO:0006457;proteolysis#GO:0006508;autophagosome assembly#GO:0000045;catabolic process#GO:0009056;autophagosome organization#GO:1905037;protein metabolic process#GO:0019538;autophagy#GO:0006914;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 membrane protein complex#GO:0098796;ER membrane protein complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=589|UniProtKB=Q9H1Y0 Q9H1Y0 ATG5 PTHR13040:SF2 AUTOPHAGY PROTEIN 5 AUTOPHAGY PROTEIN 5 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;C-terminal protein amino acid modification#GO:0018410;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organelle disassembly#GO:1903008;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;lipoprotein metabolic process#GO:0042157;cellular response to stress#GO:0033554;autophagy of nucleus#GO:0044804;autophagy#GO:0006914 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;whole membrane#GO:0098805 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=11728|UniProtKB=P54274 P54274 TERF1 PTHR46734:SF3 TELOMERIC REPEAT-BINDING FACTOR 1 TERF1 TELOMERIC REPEAT-BINDING FACTOR 1 cytoskeletal protein binding#GO:0008092;nucleic acid binding#GO:0003676;RNA-directed DNA polymerase activity#GO:0003964;tubulin binding#GO:0015631;DNA binding, bending#GO:0008301;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;microtubule binding#GO:0008017;double-stranded DNA binding#GO:0003690;telomerase activity#GO:0003720;sequence-specific DNA binding#GO:0043565;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;catalytic activity, acting on DNA#GO:0140097;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;DNA polymerase activity#GO:0034061 telomere maintenance via telomere lengthening#GO:0010833;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;telomere-telomerase complex assembly#GO:1905324;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;RNA-dependent DNA biosynthetic process#GO:0006278;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of hydrolase activity#GO:0051346;negative regulation of biological process#GO:0048519;negative regulation of DNA replication#GO:0008156;telomere organization#GO:0032200;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;telomere maintenance via telomerase#GO:0007004;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;DNA replication#GO:0006260;negative regulation of catalytic activity#GO:0043086;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of DNA replication#GO:0006275;negative regulation of molecular function#GO:0044092;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;nuclear telomere cap complex#GO:0000783;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781;protein-DNA complex#GO:0032993;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29195|UniProtKB=Q9UPN7 Q9UPN7 PPP6R1 PTHR12634:SF13 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 1 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;regulation of phosphoprotein phosphatase activity#GO:0043666;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of phosphatase activity#GO:0010921;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphatase modulator#PC00184 HUMAN|HGNC=17623|UniProtKB=Q9Y5A7 Q9Y5A7 NUB1 PTHR12948:SF3 NEDD8 ULTIMATE BUSTER-1 BS4 PROTEIN NEDD8 ULTIMATE BUSTER 1 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=14442|UniProtKB=Q8NDH6 Q8NDH6 ICA1L PTHR10164:SF5 ISLET CELL AUTOANTIGEN 1 ISLET CELL AUTOANTIGEN 1-LIKE PROTEIN biological regulation#GO:0065007;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=16055|UniProtKB=Q9BY10 Q9BY10 SLC46A2 PTHR23507:SF3 ZGC:174356 THYMIC STROMAL COTRANSPORTER HOMOLOG HUMAN|HGNC=11186|UniProtKB=Q99523 Q99523 SORT1 PTHR12106:SF23 SORTILIN RELATED SORTILIN Golgi to endosome transport#GO:0006895;cellular localization#GO:0051641;membrane organization#GO:0061024;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=4510|UniProtKB=Q969F8 Q969F8 KISS1R PTHR24230:SF78 G-PROTEIN COUPLED RECEPTOR KISS-1 RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=28741|UniProtKB=Q86SU0 Q86SU0 ILDR1 PTHR15923:SF3 TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING RECEPTOR 1 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=14946|UniProtKB=Q9ULJ8 Q9ULJ8 PPP1R9A PTHR16154:SF22 NEURABIN NEURABIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 signal transduction#GO:0007165;neurogenesis#GO:0022008;second-messenger-mediated signaling#GO:0019932;calcium-mediated signaling#GO:0019722;cell projection organization#GO:0030030;developmental process#GO:0032502;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;neuron differentiation#GO:0030182;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;neuron projection development#GO:0031175;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron development#GO:0048666;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 synapse#GO:0045202;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=11177|UniProtKB=P35610 P35610 SOAT1 PTHR10408:SF6 STEROL O-ACYLTRANSFERASE STEROL O-ACYLTRANSFERASE 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;amide binding#GO:0033218;sterol binding#GO:0032934;O-acyltransferase activity#GO:0008374;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;cholesterol binding#GO:0015485 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;organic hydroxy compound transport#GO:0015850;lipid metabolic process#GO:0006629;macromolecule localization#GO:0033036;sterol transport#GO:0015918;transport#GO:0006810;cholesterol metabolic process#GO:0008203;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;lipid modification#GO:0030258;cellular process#GO:0009987;lipid transport#GO:0006869;primary metabolic process#GO:0044238;localization#GO:0051179;organic substance transport#GO:0071702;steroid metabolic process#GO:0008202;cholesterol transport#GO:0030301;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;lipid localization#GO:0010876;secondary alcohol metabolic process#GO:1902652;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 acyltransferase#PC00042 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 HUMAN|HGNC=3541|UniProtKB=P13726 P13726 F3 PTHR20859:SF22 INTERFERON/INTERLEUKIN RECEPTOR TISSUE FACTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to cytokine#GO:0034097;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Blood coagulation#P00011>Tissue Factor#P00450;Angiogenesis#P00005>TF#P00191 HUMAN|HGNC=1125|UniProtKB=P20290 P20290 BTF3 PTHR10351:SF28 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosol#GO:0005829;polysome#GO:0005844;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=27257|UniProtKB=Q3MIP1 Q3MIP1 ITPRIPL2 PTHR10656:SF9 CELL FATE DETERMINING PROTEIN MAB21-RELATED INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN-LIKE 2 HUMAN|HGNC=76|UniProtKB=P00519 P00519 ABL1 PTHR24418:SF438 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL1 regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067 Integrin signalling pathway#P00034>Abl#P00946;Axon guidance mediated by Slit/Robo#P00008>Abl#P00347 HUMAN|HGNC=24942|UniProtKB=Q96FE7 Q96FE7 PIK3IP1 PTHR24261:SF16 PLASMINOGEN-RELATED PHOSPHOINOSITIDE-3-KINASE-INTERACTING PROTEIN 1 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 HUMAN|HGNC=15084|UniProtKB=Q96R47 Q96R47 OR2A14 PTHR26453:SF27 OLFACTORY RECEPTOR OLFACTORY RECEPTOR-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=7174|UniProtKB=P09237 P09237 MMP7 PTHR10201:SF143 MATRIX METALLOPROTEINASE MATRILYSIN hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;CCKR signaling map#P06959>MMP7#G07290;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130;CCKR signaling map#P06959>MMP7#G06996 HUMAN|HGNC=8486|UniProtKB=Q8NGU1 Q8NGU1 OR9A1P PTHR24242:SF126 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 9A1-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=17368|UniProtKB=Q5VVH5 Q5VVH5 IRAK1BP1 PTHR18842:SF2 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;intracellular signal transduction#GO:0035556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;I-kappaB kinase/NF-kappaB signaling#GO:0007249;regulation of DNA-binding transcription factor activity#GO:0051090;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;positive regulation of DNA-binding transcription factor activity#GO:0051091;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=9547|UniProtKB=P62191 P62191 PSMC1 PTHR23073:SF77 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 4 pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;TBP-class protein binding#GO:0017025;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;transcription factor binding#GO:0008134;ATPase activity#GO:0016887 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;proteasome regulatory particle, base subcomplex#GO:0008540 protease#PC00190 HUMAN|HGNC=18169|UniProtKB=Q96AY3 Q96AY3 FKBP10 PTHR46046:SF3 FAMILY NOT NAMED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP10 HUMAN|HGNC=18206|UniProtKB=Q9H336 Q9H336 CRISPLD1 PTHR10334:SF73 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN LCCL DOMAIN-CONTAINING 1 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 HUMAN|HGNC=13726|UniProtKB=Q8NEZ4 Q8NEZ4 KMT2C PTHR45888:SF1 HL01030P-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE 2C N-methyltransferase activity#GO:0008170;binding#GO:0005488;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;transcription coactivator activity#GO:0003713;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;histone binding#GO:0042393;histone-lysine N-methyltransferase activity#GO:0018024;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transferase activity#GO:0016740;protein binding#GO:0005515;molecular function regulator#GO:0098772;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=13576|UniProtKB=Q5SWL7 Q5SWL7 PRAMEF14 PTHR14224:SF81 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 1-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=11589|UniProtKB=P62380 P62380 TBPL1 PTHR10126:SF60 TATA-BOX BINDING PROTEIN TATA BOX-BINDING PROTEIN-LIKE 1 transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 nucleic acid-templated transcription#GO:0097659;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;DNA-templated transcription, initiation#GO:0006352;transcription, DNA-templated#GO:0006351;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription by RNA polymerase I#P00022>TBP#P00657;General transcription regulation#P00023>TBP#P00670;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399 HUMAN|HGNC=20629|UniProtKB=Q8N972 Q8N972 ZNF709 PTHR24379:SF105 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 709 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15768|UniProtKB=Q9NZT2 Q9NZT2 OGFR PTHR14015:SF1 OPIOID GROWTH FACTOR RECEPTOR OGFR ZETA-TYPE OPIOID RECEPTOR OPIOID GROWTH FACTOR RECEPTOR transmembrane signal receptor#PC00197 HUMAN|HGNC=29098|UniProtKB=Q9Y4C8 Q9Y4C8 RBM19 PTHR23147:SF48 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 19-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA splicing factor#PC00148 HUMAN|HGNC=27405|UniProtKB=Q6UXI9 Q6UXI9 NPNT PTHR24050:SF19 PA14 DOMAIN-CONTAINING PROTEIN NEPHRONECTIN HUMAN|HGNC=19666|UniProtKB=Q8NFX7 Q8NFX7 STXBP6 PTHR16092:SF28 SEC3/SYNTAXIN-RELATED EXOCYST COMPLEX COMPONENT 1-RELATED phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;phospholipid binding#GO:0005543;GTP-Rho binding#GO:0017049;phosphatidylinositol phosphate binding#GO:1901981;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;phosphatidylinositol bisphosphate binding#GO:1902936;Ras GTPase binding#GO:0017016;protein binding#GO:0005515;lipid binding#GO:0008289;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167 vesicle fusion#GO:0006906;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;exocytic process#GO:0140029;Golgi to plasma membrane transport#GO:0006893;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;vesicle organization#GO:0016050;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 SNARE protein#PC00034 HUMAN|HGNC=17809|UniProtKB=Q86US8 Q86US8 SMG6 PTHR15696:SF0 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 TELOMERASE-BINDING PROTEIN EST1A sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;heterocyclic compound binding#GO:1901363;telomerase RNA binding#GO:0070034 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;telomerase holoenzyme complex#GO:0005697;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=13698|UniProtKB=Q9NYZ3 Q9NYZ3 GTSE1 PTHR21584:SF10 DIFFERENTIAL DISPLAY AND ACTIVATED BY P53 DDA3 /G2 S PHASE EXPRESSED 1 G2 AND S PHASE-EXPRESSED PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoplasmic microtubule#GO:0005881;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 p53 pathway#P00059>B99#G04697;p53 pathway#P00059>B99#P04613 HUMAN|HGNC=2451|UniProtKB=P48729 P48729 CSNK1A1 PTHR11909:SF84 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of canonical Wnt signaling pathway#GO:0060828;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;peptidyl-serine modification#GO:0018209;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of Wnt signaling pathway#GO:0030178 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;CCKR signaling map#P06959>CK1#P07049;Hedgehog signaling pathway#P00025>Casein kinase I#P00681;Parkinson disease#P00049>Casein kinase I#P01242 HUMAN|HGNC=28916|UniProtKB=Q8N9B5 Q8N9B5 JMY PTHR23330:SF8 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED JUNCTION-MEDIATING AND -REGULATORY PROTEIN transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;regulation of actin polymerization or depolymerization#GO:0008064;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;transcription, DNA-templated#GO:0006351;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of molecular function#GO:0065009;apoptotic process#GO:0006915;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cell cycle arrest#GO:0007050;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of organelle organization#GO:0010638;RNA metabolic process#GO:0016070;positive regulation of actin filament polymerization#GO:0030838;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;positive regulation of molecular function#GO:0044093;actin filament polymerization#GO:0030041;biosynthetic process#GO:0009058;signal transduction by p53 class mediator#GO:0072331;regulation of transcription, DNA-templated#GO:0006355;regulation of protein-containing complex assembly#GO:0043254;organic cyclic compound metabolic process#GO:1901360;positive regulation of programmed cell death#GO:0043068;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;supramolecular fiber organization#GO:0097435;cell death#GO:0008219;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of protein polymerization#GO:0032271;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;regulation of anatomical structure size#GO:0090066;positive regulation of apoptotic process#GO:0043065;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of apoptotic process#GO:0042981;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of actin filament length#GO:0030832;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;positive regulation of protein-containing complex assembly#GO:0031334;regulation of cellular component size#GO:0032535;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of supramolecular fiber organization#GO:1902903;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;Arp2/3 complex-mediated actin nucleation#GO:0034314;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;protein polymerization#GO:0051258;regulation of cell death#GO:0010941;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;positive regulation of cytoskeleton organization#GO:0051495;regulation of nucleic acid-templated transcription#GO:1903506;actin cytoskeleton organization#GO:0030036;positive regulation of cell death#GO:0010942;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=37093|UniProtKB=P0CG38 P0CG38 POTEI PTHR24118:SF56 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER I-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=16892|UniProtKB=P40200 P40200 CD96 PTHR15317:SF1 T-CELL SURFACE PROTEIN TACTILE T-CELL SURFACE PROTEIN TACTILE response to stimulus#GO:0050896;response to stress#GO:0006950;cell-matrix adhesion#GO:0007160;biological adhesion#GO:0022610;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;defense response#GO:0006952;inflammatory response#GO:0006954 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=9360|UniProtKB=P14222 P14222 PRF1 PTHR46096:SF3 PERFORIN-1 PERFORIN-1 HUMAN|HGNC=9919|UniProtKB=P09455 P09455 RBP1 PTHR11955:SF56 FATTY ACID BINDING PROTEIN RETINOL-BINDING PROTEIN 1 HUMAN|HGNC=51249|UniProtKB=M0QZC1 M0QZC1 RNF225 PTHR22791:SF1 UNCHARACTERIZED RING FINGER PROTEIN 225 HUMAN|HGNC=6709|UniProtKB=P01374 P01374 LTA PTHR11471:SF31 TUMOR NECROSIS FACTOR FAMILY MEMBER LYMPHOTOXIN-ALPHA Apoptosis signaling pathway#P00006>TNF#P00259;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 HUMAN|HGNC=24485|UniProtKB=Q9UFP1 Q9UFP1 GASK1A PTHR15905:SF5 GOLGI-ASSOCIATED KINASE 1B-RELATED GOLGI-ASSOCIATED KINASE 1A HUMAN|HGNC=33997|UniProtKB=A0A075B759 A0A075B759 PPIAL4E PTHR11071:SF466 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A-LIKE 4C-RELATED membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=27172|UniProtKB=Q75VX8 Q75VX8 GAREM2 PTHR14454:SF5 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 2 HUMAN|HGNC=4928|UniProtKB=P10072 P10072 ZNF875 PTHR24381:SF358 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 875 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9829|UniProtKB=P04049 P04049 RAF1 PTHR44329:SF22 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cell periphery#GO:0071944;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 VEGF signaling pathway#P00056>Raf#P01417;Integrin signalling pathway#P00034>Raf#P00924;PDGF signaling pathway#P00047>Raf#P01161;Angiogenesis#P00005>Raf#P00243;FGF signaling pathway#P00021>Raf-1#P00643;Ras Pathway#P04393>Raf#P04556;B cell activation#P00010>Raf#P00381;Gonadotropin-releasing hormone receptor pathway#P06664>c-Raf#P06832;T cell activation#P00053>Raf#P01311;CCKR signaling map#P06959>RAF1#P07085;EGF receptor signaling pathway#P00018>Raf-1#P00560;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Raf#P00893;Endothelin signaling pathway#P00019>Raf-1#P00587;Interleukin signaling pathway#P00036>Raf#P00983;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Raf1#P05928;CCKR signaling map#P06959>c-RAF / RAF1#P07213;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Raf-1#P00843 HUMAN|HGNC=16027|UniProtKB=Q5JSP0 Q5JSP0 FGD3 PTHR12673:SF14 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 3 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cell projection assembly#GO:0030031 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=22199|UniProtKB=O75128 O75128 COBL PTHR47008:SF1 PROTEIN CORDON-BLEU PROTEIN CORDON-BLEU cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein-containing complex assembly#GO:0065003;actin polymerization or depolymerization#GO:0008154;actin filament polymerization#GO:0030041;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;protein polymerization#GO:0051258;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;protein-containing complex subunit organization#GO:0043933 supramolecular complex#GO:0099080;perinuclear region of cytoplasm#GO:0048471;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;actin filament#GO:0005884;intracellular organelle#GO:0043229;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;ruffle#GO:0001726;distal axon#GO:0150034;plasma membrane region#GO:0098590;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cortical cytoskeleton#GO:0030863;neuronal cell body#GO:0043025;dendrite#GO:0030425;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;cell cortex#GO:0005938;dendritic tree#GO:0097447;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;axon#GO:0030424;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;cell body#GO:0044297;neuron projection#GO:0043005;cytoskeleton#GO:0005856;growth cone#GO:0030426;site of polarized growth#GO:0030427;plasma membrane#GO:0005886 HUMAN|HGNC=30677|UniProtKB=Q92917 Q92917 GPKOW PTHR15818:SF2 G PATCH AND KOW-CONTAINING G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=25864|UniProtKB=Q53FP2 Q53FP2 TMEM35A PTHR13163:SF0 SPINAL CORD EXPRESSION PROTEIN 4 TRANSMEMBRANE PROTEIN 35A HUMAN|HGNC=17165|UniProtKB=Q9UBB9 Q9UBB9 TFIP11 PTHR23329:SF1 TUFTELIN-INTERACTING PROTEIN 11-RELATED TUFTELIN-INTERACTING PROTEIN 11 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein-containing complex disassembly#GO:0032984;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 U6 snRNP#GO:0005688;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Lsm2-8 complex#GO:0120115;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=8223|UniProtKB=Q15612 Q15612 OR1Q1 PTHR48001:SF56 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1Q1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=6892|UniProtKB=Q9UPY8 Q9UPY8 MAPRE3 PTHR10623:SF10 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER 3 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;microtubule polymerization or depolymerization#GO:0031109;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of microtubule cytoskeleton organization#GO:0070507;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;protein localization to organelle#GO:0033365;cellular component assembly#GO:0022607;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;protein localization#GO:0008104;organelle assembly#GO:0070925;localization#GO:0051179;protein localization to cytoskeleton#GO:0044380;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;microtubule organizing center#GO:0005815;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;spindle#GO:0005819;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=10621|UniProtKB=O00626 O00626 CCL22 PTHR12015:SF102 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 22 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=12224|UniProtKB=A0A0A0MS05 A0A0A0MS05 TRBV5-7 PTHR23268:SF6 T-CELL RECEPTOR BETA CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=37492|UniProtKB=A6NJY1 A6NJY1 SLC9B1P1 PTHR31102:SF5 FAMILY NOT NAMED SLC9B1-LIKE PROTEIN SLC9B1P1-RELATED localization#GO:0051179;cation transport#GO:0006812;monovalent inorganic cation transport#GO:0015672;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810 HUMAN|HGNC=25075|UniProtKB=Q8TDW0 Q8TDW0 LRRC8C PTHR45752:SF24 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8C hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 scaffold/adaptor protein#PC00226 HUMAN|HGNC=49389|UniProtKB=E9PQX1 E9PQX1 TMEM262 PTHR37998:SF1 TRANSMEMBRANE PROTEIN 262 TRANSMEMBRANE PROTEIN 262 HUMAN|HGNC=228|UniProtKB=Q9BUB4 Q9BUB4 ADAT1 PTHR46516:SF1 TRNA-SPECIFIC ADENOSINE DEAMINASE 1 TRNA-SPECIFIC ADENOSINE DEAMINASE 1 RNA processing factor#PC00147 HUMAN|HGNC=49847|UniProtKB=P0DMW3 P0DMW3 SMIM10L1 PTHR34446:SF5 SMALL INTEGRAL MEMBRANE PROTEIN 10 SMALL INTEGRAL MEMBRANE PROTEIN 10-LIKE PROTEIN 1 HUMAN|HGNC=17245|UniProtKB=Q8N4T0 Q8N4T0 CPA6 PTHR11705:SF18 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A6 hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=32431|UniProtKB=Q6UXZ0 Q6UXZ0 TMIGD1 PTHR12231:SF219 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=2464|UniProtKB=P13611 P13611 VCAN PTHR22804:SF6 AGGRECAN/VERSICAN PROTEOGLYCAN VERSICAN CORE PROTEIN extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=19995|UniProtKB=Q6DWJ6 Q6DWJ6 GPR139 PTHR46272:SF3 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTOR 139-RELATED HUMAN|HGNC=10761|UniProtKB=Q15047 Q15047 SETDB1 PTHR46024:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS HISTONE-LYSINE N-METHYLTRANSFERASE SETDB1 N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 negative regulation of gene expression#GO:0010629;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;histone methylation#GO:0016571;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of chromatin assembly or disassembly#GO:0001672;protein alkylation#GO:0008213;transcription, DNA-templated#GO:0006351;protein methylation#GO:0006479;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of chromatin organization#GO:1902275;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;macromolecule methylation#GO:0043414;heterochromatin organization#GO:0070828;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of chromatin assembly#GO:0010847;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;chromatin assembly or disassembly#GO:0006333;negative regulation of biological process#GO:0048519;positive regulation of organelle organization#GO:0010638;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of cellular component biogenesis#GO:0044089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;peptidyl-lysine methylation#GO:0018022;negative regulation of biosynthetic process#GO:0009890;heterochromatin assembly#GO:0031507;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;histone lysine methylation#GO:0034968;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;methylation#GO:0032259;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=29228|UniProtKB=Q9ULI2 Q9ULI2 RIMKLB PTHR21621:SF5 RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN BETA-CITRYLGLUTAMATE SYNTHASE B ligase activity#GO:0016874;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ribosomal protein#PC00202 HUMAN|HGNC=1077|UniProtKB=O00238 O00238 BMPR1B PTHR23255:SF62 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B signaling receptor activity#GO:0038023;SMAD binding#GO:0046332;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;response to BMP#GO:0071772;cellular protein metabolic process#GO:0044267;pattern specification process#GO:0007389;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;multicellular organism development#GO:0007275;BMP signaling pathway#GO:0030509;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 HUMAN|HGNC=17018|UniProtKB=Q9Y6Y8 Q9Y6Y8 SEC23IP PTHR23509:SF4 PA-PL1 PHOSPHOLIPASE FAMILY SEC23-INTERACTING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 cytoplasm#GO:0005737;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi-associated vesicle#GO:0005798;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;vesicle#GO:0031982;intracellular organelle#GO:0043229 phospholipase#PC00186 HUMAN|HGNC=8952|UniProtKB=P50452 P50452 SERPINB8 PTHR11461:SF166 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B8 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 protease inhibitor#PC00191 HUMAN|HGNC=23282|UniProtKB=Q8N307 Q8N307 MUC20 PTHR37358:SF1 MUCIN-20 MUCIN-20 HUMAN|HGNC=29283|UniProtKB=Q9P266 Q9P266 JCAD PTHR34757:SF1 JUNCTIONAL PROTEIN ASSOCIATED WITH CORONARY ARTERY DISEASE JUNCTIONAL PROTEIN ASSOCIATED WITH CORONARY ARTERY DISEASE positive regulation of angiogenesis#GO:0045766;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;endothelial cell proliferation#GO:0001935;positive regulation of cell population proliferation#GO:0008284;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;cell population proliferation#GO:0008283;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;tube morphogenesis#GO:0035239;epithelial cell proliferation#GO:0050673;vasculature development#GO:0001944;sprouting angiogenesis#GO:0002040;positive regulation of epithelial cell proliferation#GO:0050679;positive regulation of biological process#GO:0048518;circulatory system development#GO:0072359;regulation of multicellular organismal process#GO:0051239;regulation of cell population proliferation#GO:0042127;blood vessel morphogenesis#GO:0048514;multicellular organism development#GO:0007275;tube development#GO:0035295;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;positive regulation of multicellular organismal process#GO:0051240 anchoring junction#GO:0070161;cell-cell junction#GO:0005911;cell junction#GO:0030054;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;plasma membrane region#GO:0098590;adherens junction#GO:0005912;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=20716|UniProtKB=Q9H0B6 Q9H0B6 KLC2 PTHR45783:SF2 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 2 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 HUMAN|HGNC=9657|UniProtKB=P54829 P54829 PTPN5 PTHR46198:SF1 PROTEIN-TYROSINE-PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 5 HUMAN|HGNC=24537|UniProtKB=Q9UQN3 Q9UQN3 CHMP2B PTHR10476:SF40 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2B endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;peptide transport#GO:0015833;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=25836|UniProtKB=Q6ZS17 Q6ZS17 RIPOR1 PTHR15829:SF1 PROTEIN KINASE PKN/PRK1, EFFECTOR RHO FAMILY-INTERACTING CELL POLARIZATION REGULATOR 1 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=22140|UniProtKB=Q8IXL6 Q8IXL6 FAM20C PTHR12450:SF11 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 EXTRACELLULAR SERINE/THREONINE PROTEIN KINASE FAM20C transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=23613|UniProtKB=Q86UG4 Q86UG4 SLCO6A1 PTHR11388:SF95 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 6A1 secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=4439|UniProtKB=P07359 P07359 GP1BA PTHR24373:SF355 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN PLATELET GLYCOPROTEIN IB ALPHA CHAIN extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 Blood coagulation#P00011>GP Ibalpha#P00449 HUMAN|HGNC=18755|UniProtKB=Q9NR33 Q9NR33 POLE4 PTHR10252:SF79 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DNA POLYMERASE EPSILON SUBUNIT 4 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;transferase complex#GO:1990234;epsilon DNA polymerase complex#GO:0008622;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=7399|UniProtKB=P13640 P13640 MT1G PTHR23299:SF53 METALLOTHIONEIN METALLOTHIONEIN 1H-LIKE PROTEIN 1-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;transition metal ion homeostasis#GO:0055076;response to metal ion#GO:0010038;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;response to toxic substance#GO:0009636;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=2317|UniProtKB=Q96A23 Q96A23 CPNE4 PTHR10857:SF4 COPINE COPINE-4 calcium-dependent phospholipid binding#GO:0005544;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;binding#GO:0005488 response to metal ion#GO:0010038;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=10778|UniProtKB=Q6FHJ7 Q6FHJ7 SFRP4 PTHR11309:SF7 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;non-canonical Wnt signaling pathway#GO:0035567;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;intracellular#GO:0005622;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>FrzB#P01461 HUMAN|HGNC=30125|UniProtKB=Q8WU39 Q8WU39 MZB1 PTHR15881:SF2 MARGINAL ZONE B- AND B1-CELL-SPECIFIC PROTEIN MARGINAL ZONE B- AND B1-CELL-SPECIFIC PROTEIN B cell proliferation#GO:0042100;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;production of molecular mediator of immune response#GO:0002440;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;leukocyte proliferation#GO:0070661;regulation of biosynthetic process#GO:0009889;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of immune system process#GO:0002682;positive regulation of immune effector process#GO:0002699;B cell activation#GO:0042113;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252;leukocyte activation#GO:0045321;regulation of lymphocyte activation#GO:0051249;mononuclear cell proliferation#GO:0032943;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;immunoglobulin production#GO:0002377;regulation of cell population proliferation#GO:0042127;lymphocyte activation#GO:0046649;macromolecule metabolic process#GO:0043170;positive regulation of immune system process#GO:0002684;lymphocyte proliferation#GO:0046651;organic substance biosynthetic process#GO:1901576;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cell activation#GO:0001775;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;regulation of production of molecular mediator of immune response#GO:0002700;positive regulation of immunoglobulin production#GO:0002639;regulation of leukocyte proliferation#GO:0070663;regulation of metabolic process#GO:0019222;regulation of B cell proliferation#GO:0030888 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=17210|UniProtKB=Q8IY37 Q8IY37 DHX37 PTHR18934:SF99 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX37-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA helicase#PC00032 HUMAN|HGNC=29008|UniProtKB=Q9UEG4 Q9UEG4 ZNF629 PTHR24376:SF78 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 629 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1317|UniProtKB=P16383 P16383 GCFC2 PTHR12214:SF3 GC-RICH SEQUENCE DNA-BINDING FACTOR GC-RICH SEQUENCE DNA-BINDING FACTOR 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=12483|UniProtKB=P60604 P60604 UBE2G2 PTHR24067:SF154 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 Parkinson disease#P00049>Ubc7#P01220;Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=6664|UniProtKB=P28300 P28300 LOX PTHR45817:SF6 LYSYL OXIDASE-LIKE-RELATED PROTEIN-LYSINE 6-OXIDASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175 HUMAN|HGNC=16811|UniProtKB=Q9UJT1 Q9UJT1 TUBD1 PTHR11588:SF4 TUBULIN TUBULIN DELTA CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 HUMAN|HGNC=12475|UniProtKB=P62837 P62837 UBE2D2 PTHR24068:SF330 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D2-RELATED ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=23292|UniProtKB=P60321 P60321 NANOS2 PTHR12887:SF10 NANOS PROTEIN NANOS HOMOLOG 2 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;reproductive process#GO:0022414;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;cellular developmental process#GO:0048869;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;negative regulation of translation#GO:0017148;peptide biosynthetic process#GO:0043043;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;peptide metabolic process#GO:0006518;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;biosynthetic process#GO:0009058;translation#GO:0006412;cell differentiation#GO:0030154;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism reproduction#GO:0032504;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;multi-organism process#GO:0051704;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;perinuclear region of cytoplasm#GO:0048471;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=6391|UniProtKB=Q14807 Q14807 KIF22 PTHR24115:SF801 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF22 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=1990|UniProtKB=Q8WWK9 Q8WWK9 CKAP2 PTHR16076:SF8 CYTOSKELETON ASSOCIATED PROTEIN 2-RELATED CYTOSKELETON-ASSOCIATED PROTEIN 2 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=15939|UniProtKB=Q14508 Q14508 WFDC2 PTHR19441:SF34 WHEY ACDIC PROTEIN WAP WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 2 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antibacterial humoral response#GO:0019731;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=16641|UniProtKB=Q86UU9 Q86UU9 TAC4 PTHR11250:SF2 TACHYKININ TACHYKININ-4 HUMAN|HGNC=30590|UniProtKB=O95807 O95807 TMEM50A PTHR13180:SF1 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50A endosomal transport#GO:0016197;establishment of protein localization to vacuole#GO:0072666;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;cellular protein localization#GO:0034613;vacuolar transport#GO:0007034;transport#GO:0006810;protein localization to vacuole#GO:0072665;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;late endosome to vacuole transport#GO:0045324;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 HUMAN|HGNC=8763|UniProtKB=Q53EL6 Q53EL6 PDCD4 PTHR12626:SF3 PROGRAMMED CELL DEATH 4 PROGRAMMED CELL DEATH PROTEIN 4 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 translation factor#PC00223 HUMAN|HGNC=26929|UniProtKB=Q9Y2V0 Q9Y2V0 CDIN1 PTHR31661:SF1 SIMILAR TO CDNA SEQUENCE BC052040 CDAN1-INTERACTING NUCLEASE 1 HUMAN|HGNC=21622|UniProtKB=Q8TC20 Q8TC20 CAGE1 PTHR36864:SF1 CANCER-ASSOCIATED GENE 1 PROTEIN CANCER-ASSOCIATED GENE 1 PROTEIN HUMAN|HGNC=28512|UniProtKB=A6NEQ2 A6NEQ2 FAM181B PTHR33766:SF2 PROTEIN FAM181B PROTEIN FAM181B HUMAN|HGNC=12333|UniProtKB=P48995 P48995 TRPC1 PTHR10117:SF56 TRANSIENT RECEPTOR POTENTIAL CHANNEL SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;anion binding#GO:0043168;ion binding#GO:0043167;inorganic cation transmembrane transporter activity#GO:0022890 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 HUMAN|HGNC=11244|UniProtKB=P00995 P00995 SPINK1 PTHR21312:SF27 SERINE PROTEASE INHIBITOR SERINE PROTEASE INHIBITOR KAZAL-TYPE 1 protease inhibitor#PC00191 HUMAN|HGNC=26553|UniProtKB=Q96M34 Q96M34 TEX55 PTHR47110:SF1 TESTIS-SPECIFIC EXPRESSED PROTEIN 55 TESTIS-SPECIFIC EXPRESSED PROTEIN 55 HUMAN|HGNC=241|UniProtKB=P18509 P18509 ADCYAP1 PTHR11213:SF1 GLUCAGON-FAMILY NEUROPEPTIDE PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE neuropeptide hormone activity#GO:0005184;receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of adenylate cyclase activity#GO:0045761;regulation of protein metabolic process#GO:0051246;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of localization#GO:0032879;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;cellular protein metabolic process#GO:0044267;regulation of protein localization#GO:0032880;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of GTPase activity#GO:0043087;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;neuropeptide signaling pathway#GO:0007218;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;nucleic acid-templated transcription#GO:0097659;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;macromolecule biosynthetic process#GO:0009059;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;positive regulation of protein metabolic process#GO:0051247;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of kinase activity#GO:0033674;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of protein modification process#GO:0031399;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;regulation of phosphorus metabolic process#GO:0051174;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;RNA biosynthetic process#GO:0032774;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;neuron projection development#GO:0031175;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;positive regulation of phosphate metabolic process#GO:0045937;regulation of ERK1 and ERK2 cascade#GO:0070372;aromatic compound biosynthetic process#GO:0019438;G protein-coupled receptor signaling pathway#GO:0007186;neuron development#GO:0048666;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;second-messenger-mediated signaling#GO:0019932;regulation of phosphate metabolic process#GO:0019220;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;regulation of cyclase activity#GO:0031279;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;positive regulation of MAPK cascade#GO:0043410;regulation of transcription, DNA-templated#GO:0006355;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;ERK1 and ERK2 cascade#GO:0070371;positive regulation of GTPase activity#GO:0043547;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338;regulation of cellular macromolecule biosynthetic process#GO:2000112;cyclic-nucleotide-mediated signaling#GO:0019935 somatodendritic compartment#GO:0036477;cell body#GO:0044297;neuronal cell body#GO:0043025;neuron projection#GO:0043005;perikaryon#GO:0043204;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 neuropeptide#PC00162 Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#P06800;Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#G06879;Gonadotropin-releasing hormone receptor pathway#P06664>PACAP#G06667 HUMAN|HGNC=24133|UniProtKB=Q9ULZ2 Q9ULZ2 STAP1 PTHR16186:SF10 SIGNAL-TRANSDUCING ADAPTOR PROTEIN-RELATED SIGNAL-TRANSDUCING ADAPTOR PROTEIN 1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=26462|UniProtKB=Q0VAA5 Q0VAA5 PLCXD2 PTHR13593:SF32 UNCHARACTERIZED PI-PLC X DOMAIN-CONTAINING PROTEIN 2 HUMAN|Gene_ORFName=UNQ150/PRO176|UniProtKB=P62341 P62341 SELENOT PTHR13544:SF0 SELENOPROTEIN T THIOREDOXIN REDUCTASE-LIKE SELENOPROTEIN T disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 biological regulation#GO:0065007;regulation of biological process#GO:0050789;homeostatic process#GO:0042592;cellular process#GO:0009987;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=7777|UniProtKB=Q12968 Q12968 NFATC3 PTHR12533:SF6 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772 positive regulation of gene expression#GO:0010628;calcium-mediated signaling#GO:0019722;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252 Gonadotropin-releasing hormone receptor pathway#P06664>NFAT#P06777;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFAT#P00851;Axon guidance mediated by netrin#P00009>NFAT#P00359;Wnt signaling pathway#P00057>NFAT#P01452;T cell activation#P00053>NFAT#P01294;B cell activation#P00010>NFAT#P00367 HUMAN|HGNC=12849|UniProtKB=P31946 P31946 YWHAB PTHR18860:SF28 14-3-3 PROTEIN 14-3-3 PROTEIN BETA/ALPHA scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;FGF signaling pathway#P00021>14-3-3#P00624;EGF receptor signaling pathway#P00018>14-3-3#P00539;CCKR signaling map#P06959>14-3-3 beta/alpha#P07038 HUMAN|HGNC=20345|UniProtKB=A8K0R7 A8K0R7 ZNF839 PTHR16116:SF5 ZINC FINGER PROTEIN 839 ZINC FINGER PROTEIN 839 HUMAN|HGNC=12147|UniProtKB=A0A0B4J237 A0A0B4J237 TRAV8-2 PTHR19367:SF21 T-CELL RECEPTOR ALPHA CHAIN V REGION T CELL RECEPTOR ALPHA VARIABLE 8-2 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=30834|UniProtKB=Q8IWR1 Q8IWR1 TRIM59 PTHR24098:SF14 OUTER SEGMENT 5 TRIPARTITE MOTIF-CONTAINING PROTEIN 59 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;intraciliary transport particle B#GO:0030992;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=30635|UniProtKB=O94993 O94993 SOX30 PTHR47279:SF1 TRANSCRIPTION FACTOR SOX-30 TRANSCRIPTION FACTOR SOX-30 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=33777|UniProtKB=Q6UWW0 Q6UWW0 LCN15 PTHR11430:SF64 LIPOCALIN LIPOCALIN-15 transfer/carrier protein#PC00219 HUMAN|HGNC=28454|UniProtKB=Q9BUN8 Q9BUN8 DERL1 PTHR11009:SF1 DER1-LIKE PROTEIN, DERLIN DERLIN-1 enzyme binding#GO:0019899;protein binding#GO:0005515;protease binding#GO:0002020;binding#GO:0005488 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;cellular response to unfolded protein#GO:0034620;response to topologically incorrect protein#GO:0035966;biological regulation#GO:0065007;ubiquitin-dependent ERAD pathway#GO:0030433;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane protein complex#GO:0098796;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=28037|UniProtKB=Q9P0P0 Q9P0P0 RNF181 PTHR15710:SF170 E3 UBIQUITIN-PROTEIN LIGASE PRAJA E3 UBIQUITIN-PROTEIN LIGASE RNF181 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=26559|UniProtKB=Q5T4F4 Q5T4F4 ZFYVE27 PTHR14543:SF1 PROTRUDIN PROTRUDIN protein binding#GO:0005515;binding#GO:0005488 protein localization to plasma membrane#GO:0072659;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996 endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=23673|UniProtKB=Q7Z304 Q7Z304 MAMDC2 PTHR23282:SF116 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=20566|UniProtKB=Q7L0J3 Q7L0J3 SV2A PTHR23511:SF11 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2A bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;plasma membrane region#GO:0098590;cytoplasmic vesicle membrane#GO:0030659;cell projection#GO:0042995;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;whole membrane#GO:0098805;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=11785|UniProtKB=P07996 P07996 THBS1 PTHR10199:SF78 THROMBOSPONDIN THROMBOSPONDIN-1 negative regulation of biological process#GO:0048519;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;developmental process#GO:0032502;tube development#GO:0035295;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of biological process#GO:0050789;system development#GO:0048731;negative regulation of multicellular organismal process#GO:0051241;anatomical structure morphogenesis#GO:0009653;angiogenesis#GO:0001525;regulation of developmental process#GO:0050793;tube morphogenesis#GO:0035239;regulation of vasculature development#GO:1901342;anatomical structure development#GO:0048856;biological regulation#GO:0065007;blood vessel development#GO:0001568;vasculature development#GO:0001944;multicellular organismal process#GO:0032501 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular region#GO:0005576 p53 pathway#P00059>TSP1#G01566 HUMAN|HGNC=30164|UniProtKB=Q6FIF0 Q6FIF0 ZFAND6 PTHR10634:SF25 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE ZINC FINGER PROTEIN 6 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 cellular localization#GO:0051641;protein localization to peroxisome#GO:0072662;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;protein targeting to peroxisome#GO:0006625;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031 HUMAN|HGNC=13840|UniProtKB=P0CG08 P0CG08 GPR89B PTHR15948:SF0 G-PROTEIN COUPLED RECEPTOR 89-RELATED GOLGI PH REGULATOR A-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=1625|UniProtKB=P46094 P46094 XCR1 PTHR10489:SF730 CELL ADHESION MOLECULE CHEMOKINE XC RECEPTOR 1 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=10823|UniProtKB=O75368 O75368 SH3BGRL PTHR12232:SF5 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=13861|UniProtKB=Q9Y250 Q9Y250 LZTS1 PTHR19354:SF5 ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED ZIPPER PUTATIVE TUMOR SUPPRESSOR 1-RELATED regulation of cell morphogenesis involved in differentiation#GO:0010769;regulation of dendrite morphogenesis#GO:0048814;regulation of dendrite development#GO:0050773;neurogenesis#GO:0022008;cell projection organization#GO:0030030;regulation of anatomical structure morphogenesis#GO:0022603;dendrite development#GO:0016358;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of cellular component organization#GO:0051128;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;chemical synaptic transmission#GO:0007268;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cell-cell signaling#GO:0007267;signaling#GO:0023052;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cell morphogenesis#GO:0000902;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of neuron differentiation#GO:0045664;dendrite morphogenesis#GO:0048813;regulation of synaptic plasticity#GO:0048167;cellular component morphogenesis#GO:0032989;regulation of neuron projection development#GO:0010975;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;modulation of chemical synaptic transmission#GO:0050804;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;neuron spine#GO:0044309;dendritic spine#GO:0043197;plasma membrane#GO:0005886 HUMAN|HGNC=1172|UniProtKB=Q9UID3 Q9UID3 VPS51 PTHR15954:SF4 UNCHARACTERIZED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG endosomal transport#GO:0016197;cellular localization#GO:0051641;Golgi organization#GO:0007030;vacuolar transport#GO:0007034;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;lysosomal transport#GO:0007041;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endocytic recycling#GO:0032456;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=29072|UniProtKB=A2RUR9 A2RUR9 CCDC144A PTHR22245:SF3 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 144A-RELATED HUMAN|HGNC=12014|UniProtKB=P51580 P51580 TPMT PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 methyltransferase#PC00155 HUMAN|HGNC=24339|UniProtKB=Q5EBN2 Q5EBN2 TRIM61 PTHR24103:SF664 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 61-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=9862|UniProtKB=P61225 P61225 RAP2B PTHR24070:SF194 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-2B GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 regulation of cellular component movement#GO:0051270;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;Ras protein signal transduction#GO:0007265;regulation of localization#GO:0032879;localization of cell#GO:0051674;cell motility#GO:0048870;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of cell motility#GO:2000146;intracellular signal transduction#GO:0035556;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 HUMAN|HGNC=11405|UniProtKB=Q8IWQ3 Q8IWQ3 BRSK2 PTHR24343:SF84 SERINE/THREONINE KINASE SERINE/THREONINE-PROTEIN KINASE BRSK2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 establishment or maintenance of cell polarity#GO:0007163;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;establishment of cell polarity#GO:0030010;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular protein metabolic process#GO:0044267;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=3067|UniProtKB=Q9UNI6 Q9UNI6 DUSP12 PTHR45848:SF4 DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=25458|UniProtKB=O43934 O43934 MFSD11 PTHR23294:SF0 ET TRANSLATION PRODUCT-RELATED UNC93-LIKE PROTEIN MFSD11 HUMAN|HGNC=16778|UniProtKB=Q9BYR8 Q9BYR8 KRTAP3-1 PTHR23260:SF3 KERATIN ASSOCIATED PROTEIN 3-3-RELATED KERATIN-ASSOCIATED PROTEIN 3-1 HUMAN|HGNC=777|UniProtKB=Q15911 Q15911 ZFHX3 PTHR45891:SF4 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER HOMEOBOX PROTEIN 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;regulation of neuron differentiation#GO:0045664;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7007|UniProtKB=P61006 P61006 RAB8A PTHR47980:SF33 LD44762P RAS-RELATED PROTEIN RAB-8A cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;protein secretion#GO:0009306;regulation of localization#GO:0032879;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of secretion#GO:0051046;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;protein localization to synapse#GO:0035418;cellular response to organic substance#GO:0071310;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;response to organonitrogen compound#GO:0010243;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;protein localization to cell junction#GO:1902414;protein transport#GO:0015031;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;protein-containing complex localization#GO:0031503;receptor localization to synapse#GO:0097120;vesicle fusion#GO:0006906;macromolecule localization#GO:0033036;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;cellular protein localization#GO:0034613;transport#GO:0006810;peptide secretion#GO:0002790;cellular response to nitrogen compound#GO:1901699;amide transport#GO:0042886;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;response to peptide#GO:1901652;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;cellular response to insulin stimulus#GO:0032869;vesicle organization#GO:0016050;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;protein localization to plasma membrane#GO:0072659;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular response to chemical stimulus#GO:0070887;protein localization to membrane#GO:0072657;cellular response to peptide#GO:1901653;Golgi vesicle transport#GO:0048193;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;localization#GO:0051179;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;response to hormone#GO:0009725;membrane fusion#GO:0061025;response to chemical#GO:0042221;organelle organization#GO:0006996;biological regulation#GO:0065007 synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;clathrin-coated vesicle#GO:0030136;intracellular#GO:0005622;plasma membrane region#GO:0098590;postsynapse#GO:0098794;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;trans-Golgi network transport vesicle#GO:0030140;presynapse#GO:0098793;somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;neuron projection#GO:0043005;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 Huntington disease#P00029>Rab8#P00783 HUMAN|HGNC=13998|UniProtKB=Q9H4Q3 Q9H4Q3 PRDM13 PTHR16515:SF21 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 13 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4819|UniProtKB=Q92819 Q92819 HAS2 PTHR22913:SF7 HYALURONAN SYNTHASE HYALURONAN SYNTHASE 2 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 cellular component biogenesis#GO:0044085;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;extracellular matrix organization#GO:0030198;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;glycosaminoglycan metabolic process#GO:0030203;oxoacid metabolic process#GO:0043436;carbohydrate biosynthetic process#GO:0016051;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;polysaccharide metabolic process#GO:0005976;extracellular structure organization#GO:0043062;cellular carbohydrate metabolic process#GO:0044262;glycosaminoglycan biosynthetic process#GO:0006024;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;cellular polysaccharide biosynthetic process#GO:0033692;cellular polysaccharide metabolic process#GO:0044264;small molecule metabolic process#GO:0044281 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=4704|UniProtKB=P04921 P04921 GYPC PTHR47614:SF2 GLYCOPHORIN-C GLYCOPHORIN-C cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 HUMAN|HGNC=6554|UniProtKB=P48357 P48357 LEPR PTHR23036:SF109 CYTOKINE RECEPTOR LEPTIN RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=10728|UniProtKB=Q13275 Q13275 SEMA3F PTHR11036:SF27 SEMAPHORIN SEMAPHORIN-3F receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=1763|UniProtKB=P55283 P55283 CDH4 PTHR24027:SF81 CADHERIN-23 CADHERIN-4 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=23528|UniProtKB=A7E2V4 A7E2V4 ZSWIM8 PTHR22619:SF1 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 8 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;regulation of locomotion#GO:0040012;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;regulation of chemotaxis#GO:0050920;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;regulation of response to external stimulus#GO:0032101;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;generation of neurons#GO:0048699 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234 HUMAN|HGNC=24688|UniProtKB=Q9BZK3 Q9BZK3 NACA4P PTHR21713:SF23 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA-LIKE PROTEIN-RELATED protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;transport#GO:0006810;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;organic substance transport#GO:0071702;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=2773|UniProtKB=O76075 O76075 DFFB PTHR13067:SF2 CASPASE-ACTIVATED DNASE CIDE-N DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;catalytic activity#GO:0003824;deoxyribonuclease activity#GO:0004536 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;heterocycle catabolic process#GO:0046700;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;plasma membrane bounded cell projection organization#GO:0120036;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;cellular component disassembly#GO:0022411;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;DNA catabolic process, endonucleolytic#GO:0000737;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;cell projection assembly#GO:0030031;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;plasma membrane bounded cell projection assembly#GO:0120031;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>CAD#P00618 HUMAN|HGNC=20356|UniProtKB=Q9BXV9 Q9BXV9 GON7 PTHR37363:SF1 EKC/KEOPS COMPLEX SUBUNIT GON7 EKC/KEOPS COMPLEX SUBUNIT GON7 protein-containing complex#GO:0032991;EKC/KEOPS complex#GO:0000408;intracellular#GO:0005622 HUMAN|HGNC=25683|UniProtKB=Q9HAC8 Q9HAC8 UBTD1 PTHR13609:SF11 UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED UBIQUITIN DOMAIN-CONTAINING PROTEIN 1 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=33111|UniProtKB=Q8NCA9 Q8NCA9 ZNF784 PTHR24393:SF56 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 784 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;hematopoietic or lymphoid organ development#GO:0048534;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of hemopoiesis#GO:1903706;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=2074|UniProtKB=Q13286 Q13286 CLN3 PTHR10981:SF0 BATTENIN BATTENIN regulation of intracellular pH#GO:0051453;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;homeostatic process#GO:0042592;monovalent inorganic cation homeostasis#GO:0055067;cation transport#GO:0006812;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;organic substance transport#GO:0071702;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;basic amino acid transport#GO:0015802;ion homeostasis#GO:0050801;anion transport#GO:0006820;biological regulation#GO:0065007;regulation of cellular pH#GO:0030641 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=29318|UniProtKB=Q9HCJ0 Q9HCJ0 TNRC6C PTHR13020:SF9 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;positive regulation of biological process#GO:0048518;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;posttranscriptional gene silencing#GO:0016441;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;gene silencing by miRNA#GO:0035195;nuclear-transcribed mRNA catabolic process#GO:0000956;gene silencing by RNA#GO:0031047;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;positive regulation of RNA metabolic process#GO:0051254;cellular macromolecule catabolic process#GO:0044265 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=40912|UniProtKB=P0DJH9 P0DJH9 RD3L PTHR28489:SF3 RENTINAL DEGENERATION 3-LIKE PROTEIN RD3-LIKE HUMAN|HGNC=25539|UniProtKB=Q6PCD5 Q6PCD5 RFWD3 PTHR16047:SF7 RFWD3 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RFWD3 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=21088|UniProtKB=Q86SK9 Q86SK9 SCD5 PTHR11351:SF90 ACYL-COA DESATURASE STEAROYL-COA DESATURASE 5 cation binding#GO:0043169;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;unsaturated fatty acid biosynthetic process#GO:0006636;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;fatty acid biosynthetic process#GO:0006633;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=19991|UniProtKB=Q8IZ08 Q8IZ08 GPR135 PTHR22752:SF3 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 135 G-protein coupled receptor#PC00021 HUMAN|HGNC=18643|UniProtKB=Q8IWZ8 Q8IWZ8 SUGP1 PTHR23340:SF3 ARGININE/SERINE RICH SPLICING FACTOR SF4/14 SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 1 RNA splicing factor#PC00148 HUMAN|HGNC=9878|UniProtKB=O95267 O95267 RASGRP1 PTHR23113:SF174 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 1 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 HUMAN|HGNC=9983|UniProtKB=P48378 P48378 RFX2 PTHR12619:SF17 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=10061|UniProtKB=Q99496 Q99496 RNF2 PTHR46076:SF4 E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RING2 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;chromatin binding#GO:0003682;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity, acting on a protein#GO:0140096 protein ubiquitination#GO:0016567;histone H2A ubiquitination#GO:0033522;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;histone ubiquitination#GO:0016574;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|Ensembl=ENSG00000225110|UniProtKB=A0A0J9YX94 A0A0J9YX94 PNMA6F PTHR23095:SF49 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN MA6F HUMAN|HGNC=12616|UniProtKB=Q9UMW8 Q9UMW8 USP18 PTHR24006:SF796 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBL CARBOXYL-TERMINAL HYDROLASE 18-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=2157|UniProtKB=Q15417 Q15417 CNN3 PTHR18959:SF46 CALPONIN/TRANSGELIN CALPONIN-3 non-motor actin binding protein#PC00165 HUMAN|HGNC=20681|UniProtKB=Q6ZS30 Q6ZS30 NBEAL1 PTHR13743:SF115 BEIGE/BEACH-RELATED NEUROBEACHIN-LIKE PROTEIN 1 enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 localization#GO:0051179;macromolecule localization#GO:0033036;protein localization#GO:0008104 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 HUMAN|HGNC=16061|UniProtKB=Q9NQU5 Q9NQU5 PAK6 PTHR48015:SF19 SERINE/THREONINE-PROTEIN KINASE TAO SERINE/THREONINE-PROTEIN KINASE PAK 6 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;stress-activated protein kinase signaling cascade#GO:0031098;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;positive regulation of protein kinase activity#GO:0045860;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517 HUMAN|HGNC=19762|UniProtKB=Q8IX07 Q8IX07 ZFPM1 PTHR12958:SF4 FRIEND OF GATA2-RELATED ZINC FINGER PROTEIN ZFPM1 RNA polymerase II transcription factor binding#GO:0001085;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;heart development#GO:0007507;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;biosynthetic process#GO:0009058;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;myeloid cell differentiation#GO:0030099;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;erythrocyte differentiation#GO:0030218;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=24902|UniProtKB=Q8WUY9 Q8WUY9 DEPDC1B PTHR16206:SF11 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 1B scaffold/adaptor protein#PC00226 HUMAN|HGNC=1483|UniProtKB=Q9Y6Q1 Q9Y6Q1 CAPN6 PTHR10183:SF381 CALPAIN CALPAIN-6 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=28942|UniProtKB=Q8N6L1 Q8N6L1 KRTCAP2 PTHR32001:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 2 KERATINOCYTE-ASSOCIATED PROTEIN 2 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;protein N-linked glycosylation#GO:0006487;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;glycosylation#GO:0070085;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=13050|UniProtKB=O95789 O95789 ZMYM6 PTHR45736:SF9 ZINC FINGER MYM-TYPE PROTEIN ZINC FINGER MYM-TYPE PROTEIN 6 zinc finger transcription factor#PC00244 HUMAN|HGNC=30480|UniProtKB=A8MVW0 A8MVW0 FAM171A2 PTHR31626:SF3 FAMILY NOT NAMED PROTEIN FAM171A2 HUMAN|HGNC=26233|UniProtKB=Q5JST6 Q5JST6 EFHC2 PTHR12086:SF11 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2 calmodulin-related#PC00061 HUMAN|HGNC=11000|UniProtKB=Q9Y2P4 Q9Y2P4 SLC27A6 PTHR43107:SF10 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 6 ligase activity#GO:0016874;transporter activity#GO:0005215;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;lipid transporter activity#GO:0005319 secondary carrier transporter#PC00258 HUMAN|HGNC=28281|UniProtKB=Q8WUH6 Q8WUH6 TMEM263 PTHR31443:SF0 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 263 HUMAN|HGNC=33809|UniProtKB=Q6UXQ4 Q6UXQ4 C2orf66 PTHR47620:SF1 CHROMOSOME 2 OPEN READING FRAME 66 GENE, 34066-RELATED HUMAN|HGNC=9228|UniProtKB=O14494 O14494 PLPP1 PTHR10165:SF26 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=16524|UniProtKB=P61106 P61106 RAB14 PTHR24073:SF185 DRAB5-RELATED RAS-RELATED PROTEIN RAB-14 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=2671|UniProtKB=P14920 P14920 DAO PTHR11530:SF15 D-AMINO ACID OXIDASE D-AMINO-ACID OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidase#PC00175 HUMAN|HGNC=19853|UniProtKB=Q6PJG2 Q6PJG2 MIDEAS PTHR16089:SF24 REST COREPRESSOR COREST PROTEIN-RELATED MITOTIC DEACETYLASE-ASSOCIATED SANT DOMAIN PROTEIN molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 HUMAN|HGNC=5348|UniProtKB=Q9UMF0 Q9UMF0 ICAM5 PTHR13771:SF9 INTERCELLULAR ADHESION MOLECULE INTERCELLULAR ADHESION MOLECULE 5 HUMAN|HGNC=33772|UniProtKB=Q0VGL1 Q0VGL1 LAMTOR4 PTHR33967:SF1 RAGULATOR COMPLEX PROTEIN LAMTOR4 RAGULATOR COMPLEX PROTEIN LAMTOR4 GTPase binding#GO:0051020;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;TOR signaling#GO:0031929;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane raft#GO:0045121;membrane microdomain#GO:0098857;membrane region#GO:0098589;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=27936|UniProtKB=A6NES4 A6NES4 MROH2A PTHR23120:SF14 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 2A HUMAN|HGNC=28986|UniProtKB=Q92610 Q92610 ZNF592 PTHR47222:SF1 ZINC FINGER PROTEIN 532-RELATED ZINC FINGER PROTEIN 592 HUMAN|HGNC=17366|UniProtKB=Q9UDR5 Q9UDR5 AASS PTHR11133:SF22 SACCHAROPINE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL dehydrogenase#PC00092 HUMAN|HGNC=5659|UniProtKB=A0A0C4DH38 A0A0C4DH38 IGHV5-51 PTHR23266:SF348 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 5-10-1-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=7603|UniProtKB=Q9ULV0 Q9ULV0 MYO5B PTHR13140:SF356 MYOSIN UNCONVENTIONAL MYOSIN-VB pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=11103|UniProtKB=Q12824 Q12824 SMARCB1 PTHR10019:SF5 SNF5 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY B MEMBER 1 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;ATP-dependent chromatin remodeling#GO:0043044;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of nucleic acid-templated transcription#GO:1903506;chromatin remodeling#GO:0006338;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 HUMAN|HGNC=23066|UniProtKB=Q86SZ2 Q86SZ2 TRAPPC6B PTHR12817:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=15363|UniProtKB=Q8NH40 Q8NH40 OR6S1 PTHR26454:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6S1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=21961|UniProtKB=Q6NSZ9 Q6NSZ9 ZSCAN25 PTHR23226:SF1 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 25 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=14105|UniProtKB=Q99932 Q99932 SPAG8 PTHR15510:SF5 SPERM-ASSOCIATED ANTIGEN 8 SPERM-ASSOCIATED ANTIGEN 8 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3529|UniProtKB=P03951 P03951 F11 PTHR24253:SF44 TRANSMEMBRANE PROTEASE SERINE COAGULATION FACTOR XI serine protease#PC00203 Blood coagulation#P00011>FXIa#P00434;Blood coagulation#P00011>FXI#P00460 HUMAN|HGNC=37241|UniProtKB=B2RV13 B2RV13 CFAP97D1 PTHR33768:SF5 MIP11318P CFAP97 DOMAIN-CONTAINING 1 HUMAN|HGNC=33230|UniProtKB=Q8N4W9 Q8N4W9 ZNF808 PTHR24376:SF85 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 600-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9896|UniProtKB=P98175 P98175 RBM10 PTHR13948:SF4 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 10 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|Gene=BARGIN|UniProtKB=Q6ZT62 Q6ZT62 BARGIN PTHR14130:SF12 3BP-1 RELATED RHOGAP BARGIN-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rho GTPase binding#GO:0017048;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;Rac GTPase binding#GO:0048365;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 signal transduction#GO:0007165;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;positive regulation of molecular function#GO:0044093;regulation of cellular component organization#GO:0051128;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of actin cytoskeleton organization#GO:0032956;regulation of hydrolase activity#GO:0051336;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of GTPase activity#GO:0043087;positive regulation of GTPase activity#GO:0043547;positive regulation of catalytic activity#GO:0043085;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;actin cytoskeleton organization#GO:0030036;regulation of Ras protein signal transduction#GO:0046578 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=9128|UniProtKB=Q13401 Q13401 PMS2P3 PTHR10073:SF52 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MISMATCH REPAIR ENDONUCLEASE PMS2-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;DNA repair complex#GO:1990391;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=27387|UniProtKB=Q6UX98 Q6UX98 ZDHHC24 PTHR22883:SF414 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC24-RELATED transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=24357|UniProtKB=Q9H5V8 Q9H5V8 CDCP1 PTHR14477:SF1 CUB DOMAIN-CONTAINING PROTEIN 1 CUB DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=15815|UniProtKB=Q7Z478 Q7Z478 DHX29 PTHR18934:SF202 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX29 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 RNA helicase#PC00032 HUMAN|HGNC=37286|UniProtKB=A6NGH7 A6NGH7 CCDC160 PTHR48251:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 160 COILED-COIL DOMAIN-CONTAINING PROTEIN 160 HUMAN|HGNC=11851|UniProtKB=O60602 O60602 TLR5 PTHR24365:SF525 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;pattern recognition receptor signaling pathway#GO:0002221;cellular process#GO:0009987;defense response#GO:0006952;signaling#GO:0023052;inflammatory response#GO:0006954 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=16938|UniProtKB=Q8TCB0 Q8TCB0 IFI44 PTHR14241:SF3 INTERFERON-INDUCED PROTEIN 44 INTERFERON-INDUCED PROTEIN 44 HUMAN|HGNC=25102|UniProtKB=Q8NBR0 Q8NBR0 TP53I13 PTHR34179:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=8905|UniProtKB=P36871 P36871 PGM1 PTHR22573:SF37 PHOSPHOHEXOMUTASE FAMILY MEMBER PHOSPHOGLUCOMUTASE-1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;organic substance metabolic process#GO:0071704;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 mutase#PC00160 HUMAN|HGNC=12137|UniProtKB=A0A0B4J264 A0A0B4J264 TRAV38-1 PTHR23267:SF403 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 38-1 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=2410|UniProtKB=P07315 P07315 CRYGC PTHR11818:SF32 BETA/GAMMA CRYSTALLIN GAMMA-CRYSTALLIN C structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=6853|UniProtKB=Q99558 Q99558 MAP3K14 PTHR48016:SF9 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>MAP3K14#P07063;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Apoptosis signaling pathway#P00006>NIK#P00324 HUMAN|Ensembl=ENSG00000233757|UniProtKB=A0A087WUV0 A0A087WUV0 ENSG00000233757 PTHR24377:SF956 IP01015P-RELATED SUBFAMILY NOT NAMED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=1107|UniProtKB=Q07352 Q07352 ZFP36L1 PTHR12547:SF53 CCCH ZINC FINGER/TIS11-RELATED MRNA DECAY ACTIVATOR PROTEIN ZFP36L1 RNA metabolism protein#PC00031 HUMAN|HGNC=12017|UniProtKB=P12270 P12270 TPR PTHR18898:SF2 NUCLEOPROTEIN TPR-RELATED NUCLEOPROTEIN TPR structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=29828|UniProtKB=Q6TFL3 Q6TFL3 CCDC171 PTHR47899:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 171 COILED-COIL DOMAIN-CONTAINING PROTEIN 171 HUMAN|HGNC=30959|UniProtKB=Q8IWR0 Q8IWR0 ZC3H7A PTHR14928:SF13 ROTAVIRUS 'X' ASSOCIATED NON-STRUCTURAL PROTEIN/ZINC FINGER CCCH DOMAIN CONTAINING 7 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7A nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression#GO:0010468;regulation of gene expression, epigenetic#GO:0040029;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;gene silencing by miRNA#GO:0035195;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;gene silencing by RNA#GO:0031047;cellular process#GO:0009987;primary metabolic process#GO:0044238;production of miRNAs involved in gene silencing by miRNA#GO:0035196;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;posttranscriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 nucleic acid metabolism protein#PC00171 HUMAN|HGNC=12101|UniProtKB=A0A0B4J248 A0A0B4J248 TRAV1-1 PTHR19433:SF105 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 1-1-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=7601|UniProtKB=Q8NEV4 Q8NEV4 MYO3A PTHR46256:SF4 AGAP011099-PA MYOSIN-IIIA Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=12578|UniProtKB=O75841 O75841 UPK1B PTHR19282:SF24 TETRASPANIN UROPLAKIN-1B response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=28498|UniProtKB=Q8TAG6 Q8TAG6 VXN PTHR31520:SF1 VEXIN VEXIN cellular developmental process#GO:0048869;system development#GO:0048731;cell differentiation#GO:0030154;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cellular process#GO:0009987;nervous system development#GO:0007399 HUMAN|HGNC=19057|UniProtKB=Q8TD26 Q8TD26 CHD6 PTHR45623:SF8 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 6 HUMAN|HGNC=5428|UniProtKB=P01567 P01567 IFNA7 PTHR11691:SF69 TYPE I INTERFERON INTERFERON ALPHA-7 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=4635|UniProtKB=P21266 P21266 GSTM3 PTHR11571:SF133 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=23693|UniProtKB=Q9UJ42 Q9UJ42 GPR160 PTHR15573:SF0 G-PROTEIN COUPLED RECEPTOR 160-RELATED G-PROTEIN COUPLED RECEPTOR 160-RELATED receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=2084|UniProtKB=Q16740 Q16740 CLPP PTHR10381:SF11 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;serine-type peptidase activity#GO:0008236;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;nucleoside-triphosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;ATPase activity#GO:0016887 macromolecule catabolic process#GO:0009057;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;intracellular#GO:0005622 serine protease#PC00203 HUMAN|HGNC=1933|UniProtKB=Q15782 Q15782 CHI3L2 PTHR11177:SF82 CHITINASE CHITINASE-3-LIKE PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;carbohydrate derivative binding#GO:0097367;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;binding#GO:0005488;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;organonitrogen compound metabolic process#GO:1901564;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;organonitrogen compound catabolic process#GO:1901565;aminoglycan metabolic process#GO:0006022;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110 HUMAN|HGNC=1844|UniProtKB=Q9BXQ6 Q9BXQ6 TMEM121B PTHR47399:SF1 TRANSMEMBRANE PROTEIN 121B TRANSMEMBRANE PROTEIN 121B HUMAN|HGNC=3754|UniProtKB=P21333 P21333 FLNA PTHR38537:SF5 JITTERBUG, ISOFORM N FILAMIN-A Nicotine pharmacodynamics pathway#P06587>FLNA#P06601;Integrin signalling pathway#P00034>Filamin#P00914;Dopamine receptor mediated signaling pathway#P05912>FLNA#P05959 HUMAN|HGNC=37225|UniProtKB=A8MZA4 A8MZA4 GOLGA6L6 PTHR23143:SF20 TRICHOHYALIN-RELATED GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 1-RELATED actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=20367|UniProtKB=Q5TBA9 Q5TBA9 FRY PTHR12295:SF29 FURRY-RELATED PROTEIN FURRY HOMOLOG cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;neuron projection development#GO:0031175;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular#GO:0005622;site of polarized growth#GO:0030427 scaffold/adaptor protein#PC00226 HUMAN|HGNC=25707|UniProtKB=Q5SQS8 Q5SQS8 C10orf120 PTHR47509:SF1 MCG1612 RIKEN CDNA 4933402N03 GENE HUMAN|HGNC=3594|UniProtKB=P49327 P49327 FASN PTHR43775:SF7 FATTY ACID SYNTHASE FATTY ACID SYNTHASE HUMAN|HGNC=10990|UniProtKB=P12235 P12235 SLC25A4 PTHR45635:SF32 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP/ATP TRANSLOCASE 1 carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organophosphate ester transmembrane transporter activity#GO:0015605;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;purine nucleotide transmembrane transporter activity#GO:0015216;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ATP transmembrane transporter activity#GO:0005347;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide transmembrane transporter activity#GO:0015215;active ion transmembrane transporter activity#GO:0022853 transfer/carrier protein#PC00219 HUMAN|HGNC=14412|UniProtKB=Q9BYV1 Q9BYV1 AGXT2 PTHR45688:SF3 FAMILY NOT NAMED ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL HUMAN|HGNC=8760|UniProtKB=Q15116 Q15116 PDCD1 PTHR15264:SF2 PROGRAMMED CELL DEATH PROTEIN 1 PROGRAMMED CELL DEATH PROTEIN 1 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;immune response#GO:0006955;regulation of immune response#GO:0050776;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=24804|UniProtKB=Q6ZNE9 Q6ZNE9 RUFY4 PTHR47732:SF1 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 4 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=104|UniProtKB=Q8NE01 Q8NE01 CNNM3 PTHR12064:SF27 ANCIENT CONSERVED DOMAIN PROTEIN-RELATED METAL TRANSPORTER CNNM3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=11953|UniProtKB=Q92752 Q92752 TNR PTHR19143:SF254 FIBRINOGEN/TENASCIN/ANGIOPOEITIN TENASCIN-R extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=19693|UniProtKB=Q9Y3A0 Q9Y3A0 COQ4 PTHR12922:SF7 UBIQUINONE BIOSYNTHESIS PROTEIN UBIQUINONE BIOSYNTHESIS PROTEIN COQ4 HOMOLOG, MITOCHONDRIAL HUMAN|HGNC=2196|UniProtKB=Q14993 Q14993 COL19A1 PTHR24023:SF938 COLLAGEN ALPHA COLLAGEN ALPHA-1(XIX) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=8350|UniProtKB=Q8NGL2 Q8NGL2 OR5L1 PTHR48018:SF32 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5L1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=31802|UniProtKB=Q96CB9 Q96CB9 NSUN4 PTHR22808:SF3 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 5-METHYLCYTOSINE RRNA METHYLTRANSFERASE NSUN4 methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;RNA methylation#GO:0001510 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 RNA methyltransferase#PC00033 HUMAN|HGNC=4194|UniProtKB=P30047 P30047 GCHFR PTHR16852:SF2 GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;negative regulation of hydrolase activity#GO:0051346;regulation of catalytic activity#GO:0050790;regulation of molecular function#GO:0065009;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095 HUMAN|HGNC=51180|UniProtKB=D6REC4 D6REC4 CFAP99 PTHR34649:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99 structural protein#PC00211 HUMAN|HGNC=9277|UniProtKB=O15297 O15297 PPM1D PTHR47992:SF79 ALPHABET, ISOFORM E-RELATED PROTEIN PHOSPHATASE 1D enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 p53 pathway feedback loops 2#P04398>WIP-1#P04650;p53 pathway#P00059>WIP-1#G04693;p53 pathway feedback loops 2#P04398>WIP-1#G04708 HUMAN|HGNC=1769|UniProtKB=O14735 O14735 CDIPT PTHR15362:SF4 PHOSPHATIDYLINOSITOL SYNTHASE CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE transferase#PC00220 HUMAN|HGNC=14915|UniProtKB=Q9NYW2 Q9NYW2 TAS2R8 PTHR11394:SF31 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 8 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=447|UniProtKB=O96006 O96006 ZBED1 PTHR46169:SF2 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA metabolism protein#PC00009 HUMAN|HGNC=20260|UniProtKB=Q96IW7 Q96IW7 SEC22A PTHR46258:SF3 LONGIN DOMAIN-CONTAINING PROTEIN VESICLE-TRAFFICKING PROTEIN SEC22A HUMAN|HGNC=2966|UniProtKB=O43237 O43237 DYNC1LI2 PTHR12688:SF1 DYNEIN LIGHT INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 LIGHT INTERMEDIATE CHAIN 2 dynein heavy chain binding#GO:0045504;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;microtubule-based movement#GO:0007018;movement of cell or subcellular component#GO:0006928;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987 microtubule organizing center#GO:0005815;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=26046|UniProtKB=Q8TBF5 Q8TBF5 PIGX PTHR28650:SF1 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN HUMAN|HGNC=20146|UniProtKB=Q6UW01 Q6UW01 CBLN3 PTHR22923:SF2 CEREBELLIN-RELATED CEREBELLIN-3 HUMAN|HGNC=27200|UniProtKB=Q1W4C9 Q1W4C9 SPINK13 PTHR21312:SF36 SERINE PROTEASE INHIBITOR SERINE PROTEASE INHIBITOR KAZAL-TYPE 13 protease inhibitor#PC00191 HUMAN|HGNC=28166|UniProtKB=Q5VUJ9 Q5VUJ9 EFCAB2 PTHR46763:SF1 DYNEIN REGULATORY COMPLEX PROTEIN 8 DYNEIN REGULATORY COMPLEX PROTEIN 8 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=12778|UniProtKB=O14904 O14904 WNT9A PTHR12027:SF75 WNT RELATED PROTEIN WNT-9A receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cell fate commitment#GO:0045165;cell-cell signaling by wnt#GO:0198738;nervous system development#GO:0007399;cellular process#GO:0009987;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=17642|UniProtKB=Q96SD1 Q96SD1 DCLRE1C PTHR23240:SF8 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED PROTEIN ARTEMIS hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;damaged DNA binding#GO:0003684;exonuclease activity#GO:0004527;deoxyribonuclease activity#GO:0004536;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;exodeoxyribonuclease activity#GO:0004529;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;exodeoxyribonuclease activity, producing 5'-phosphomonoesters#GO:0016895 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;interstrand cross-link repair#GO:0036297;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;telomere capping#GO:0016233;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;double-strand break repair via nonhomologous end joining#GO:0006303;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;chromosome organization#GO:0051276;organelle organization#GO:0006996;biological regulation#GO:0065007;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009 HUMAN|HGNC=4933|UniProtKB=P10321 P10321 HLA-C PTHR16675:SF252 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, C ALPHA CHAIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;amide binding#GO:0033218;peptide binding#GO:0042277 immune response#GO:0006955;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;T cell mediated immunity#GO:0002456;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=7523|UniProtKB=O94972 O94972 TRIM37 PTHR36754:SF2 E3 UBIQUITIN-PROTEIN LIGASE TRIM37 E3 UBIQUITIN-PROTEIN LIGASE TRIM37 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;ubiquitin protein ligase binding#GO:0031625;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;transferase activity#GO:0016740;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;tumor necrosis factor receptor binding#GO:0005164;cytokine receptor binding#GO:0005126 cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;centrosome cycle#GO:0007098;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of molecular function#GO:0065009;cytoskeleton organization#GO:0007010;histone ubiquitination#GO:0016574;negative regulation of cellular component organization#GO:0051129;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;protein modification by small protein conjugation#GO:0032446;regulation of centrosome duplication#GO:0010824;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;protein monoubiquitination#GO:0006513;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;microtubule organizing center organization#GO:0031023;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;regulation of microtubule-based process#GO:0032886;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;centrosome duplication#GO:0051298;biosynthetic process#GO:0009058;negative regulation of cell cycle process#GO:0010948;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;histone H2A ubiquitination#GO:0033522;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;centriole replication#GO:0007099;positive regulation of DNA-binding transcription factor activity#GO:0051091;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;microtubule-based process#GO:0007017;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of molecular function#GO:0044092;negative regulation of DNA-binding transcription factor activity#GO:0043433 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=11857|UniProtKB=O14894 O14894 TM4SF5 PTHR14198:SF4 TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED TRANSMEMBRANE 4 L6 FAMILY MEMBER 5 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 HUMAN|HGNC=565|UniProtKB=P53680 P53680 AP2S1 PTHR11753:SF6 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-2 COMPLEX SUBUNIT SIGMA localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 HUMAN|HGNC=10718|UniProtKB=P16581 P16581 SELE PTHR19325:SF493 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING E-SELECTIN HUMAN|Gene_ORFName=HCCS4|UniProtKB=Q9NYL2 Q9NYL2 MAP3K20 PTHR43289:SF14 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE-RELATED non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=30744|UniProtKB=P0CG34 P0CG34 TMSB15A PTHR12021:SF11 THYMOSIN BETA THYMOSIN BETA-15A-RELATED cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;cellular protein localization#GO:0034613;protein-containing complex assembly#GO:0065003;regulation of localization#GO:0032879;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;regulation of cellular component movement#GO:0051270;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of cell motility#GO:2000145;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;localization of cell#GO:0051674;actin polymerization or depolymerization#GO:0008154;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=20920|UniProtKB=Q5VWC8 Q5VWC8 HACD4 PTHR11035:SF16 PTPLA DOMAIN PROTEIN VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 4 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=18685|UniProtKB=Q7Z5P4 Q7Z5P4 HSD17B13 PTHR24322:SF499 PKSB 17-BETA-HYDROXYSTEROID DEHYDROGENASE 13 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;lipid droplet#GO:0005811;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=3724|UniProtKB=Q14318 Q14318 FKBP8 PTHR46512:SF3 PEPTIDYLPROLYL ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP8 chaperone#PC00072 HUMAN|HGNC=22423|UniProtKB=Q96H79 Q96H79 ZC3HAV1L PTHR47621:SF1 ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1-LIKE ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1-LIKE HUMAN|HGNC=12580|UniProtKB=O75631 O75631 UPK3A PTHR15446:SF17 UROPLAKIN III UROPLAKIN-3A HUMAN|HGNC=11547|UniProtKB=Q92804 Q92804 TAF15 PTHR23238:SF25 RNA BINDING PROTEIN TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=30574|UniProtKB=Q8TB69 Q8TB69 ZNF519 PTHR24384:SF225 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 519 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=15663|UniProtKB=Q9NYU2 Q9NYU2 UGGT1 PTHR11226:SF3 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 1 transferase activity, transferring hexosyl groups#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;unfolded protein binding#GO:0051082;binding#GO:0005488;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;protein binding#GO:0005515;glucosyltransferase activity#GO:0046527;transferase activity, transferring glycosyl groups#GO:0016757 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;cellular response to misfolded protein#GO:0071218;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein N-linked glycosylation via asparagine#GO:0018279;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;response to endoplasmic reticulum stress#GO:0034976;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;cellular response to organic substance#GO:0071310;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;carbohydrate derivative biosynthetic process#GO:1901137;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;protein N-linked glycosylation#GO:0006487;response to topologically incorrect protein#GO:0035966;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;glycosylation#GO:0070085 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=4400|UniProtKB=P16520 P16520 GNB3 PTHR19850:SF31 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(T) SUBUNIT BETA-3 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Dopamine receptor mediated signaling pathway#P05912>Gbeta#P05954;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Wnt signaling pathway#P00057>GBeta#P01457;PI3 kinase pathway#P00048>Gbetagamma#P01188;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;GABA-B receptor II signaling#P05731>Gbeta#P05755;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Gbetagamma#P00836;Endogenous cannabinoid signaling#P05730>Gbeta#P05745;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753 HUMAN|HGNC=6762|UniProtKB=Q9Y6D9 Q9Y6D9 MAD1L1 PTHR23168:SF0 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 negative regulation of sister chromatid segregation#GO:0033046;cellular localization#GO:0051641;regulation of mitotic nuclear division#GO:0007088;organelle localization#GO:0051640;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;regulation of mitotic sister chromatid segregation#GO:0033047;attachment of spindle microtubules to kinetochore#GO:0008608;negative regulation of cellular component organization#GO:0051129;establishment of organelle localization#GO:0051656;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;mitotic metaphase plate congression#GO:0007080;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;chromosome localization#GO:0050000;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;mitotic cell cycle phase transition#GO:0044772;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;metaphase plate congression#GO:0051310;negative regulation of organelle organization#GO:0010639;mitotic spindle assembly checkpoint#GO:0007094;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;mitotic cell cycle checkpoint#GO:0007093;regulation of nuclear division#GO:0051783;establishment of chromosome localization#GO:0051303;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;localization#GO:0051179;metaphase/anaphase transition of cell cycle#GO:0044784;negative regulation of chromosome separation#GO:1905819;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 envelope#GO:0031975;supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;nuclear envelope#GO:0005635;chromosome, centromeric region#GO:0000775;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;mitotic spindle#GO:0072686;chromosome#GO:0005694;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cytoskeleton#GO:0005856;spindle#GO:0005819;plasma membrane#GO:0005886 HUMAN|HGNC=29276|UniProtKB=Q9P2B7 Q9P2B7 CFAP97 PTHR23035:SF1 UNCHARACTERIZED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97 HUMAN|HGNC=20222|UniProtKB=Q9Y6S9 Q9Y6S9 RPS6KL1 PTHR15508:SF4 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE-LIKE 1 non-receptor serine/threonine protein kinase#PC00167 PDGF signaling pathway#P00047>p90RSK#P01142 HUMAN|HGNC=4485|UniProtKB=Q99527 Q99527 GPER1 PTHR24226:SF2 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 G-PROTEIN COUPLED ESTROGEN RECEPTOR 1 G-protein coupled receptor#PC00021 HUMAN|HGNC=18868|UniProtKB=Q6P2D8 Q6P2D8 XRRA1 PTHR22710:SF2 X-RAY RADIATION RESISTANCE ASSOCIATED PROTEIN 1 XRRA1 X-RAY RADIATION RESISTANCE-ASSOCIATED PROTEIN 1 HUMAN|HGNC=27038|UniProtKB=Q6JVE9 Q6JVE9 LCN8 PTHR11430:SF1 LIPOCALIN EPIDIDYMAL-SPECIFIC LIPOCALIN-8 transfer/carrier protein#PC00219 HUMAN|HGNC=18825|UniProtKB=Q86VE9 Q86VE9 SERINC5 PTHR10383:SF16 SERINE INCORPORATOR SERINE INCORPORATOR 5 cellular anatomical entity#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 HUMAN|HGNC=10380|UniProtKB=O15235 O15235 MRPS12 PTHR11652:SF1 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER 28S RIBOSOMAL PROTEIN S12, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;intracellular#GO:0005622 ribosomal protein#PC00202 HUMAN|HGNC=418|UniProtKB=P09972 P09972 ALDOC PTHR11627:SF3 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE C lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;fructose-bisphosphate aldolase activity#GO:0004332 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;purine ribonucleoside diphosphate metabolic process#GO:0009179;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aldolase#PC00044 Glycolysis#P00024>Aldolase#P00679;Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959 HUMAN|HGNC=14603|UniProtKB=Q9Y222 Q9Y222 DMTF1 PTHR46380:SF2 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=30762|UniProtKB=A6H8Z2 A6H8Z2 FAM221B PTHR31214:SF3 PROTEIN FAM221A-RELATED PROTEIN FAM221B HUMAN|HGNC=7050|UniProtKB=Q13296 Q13296 SCGB2A2 PTHR14037:SF7 MAMMAGLOBIN-RELATED MAMMAGLOBIN-A response to organic substance#GO:0010033;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cellular response to steroid hormone stimulus#GO:0071383;response to lipid#GO:0033993;cell communication#GO:0007154;steroid hormone mediated signaling pathway#GO:0043401;cellular process#GO:0009987;cellular response to lipid#GO:0071396;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;cellular response to hormone stimulus#GO:0032870;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;intracellular steroid hormone receptor signaling pathway#GO:0030518;biological regulation#GO:0065007;cellular response to organic cyclic compound#GO:0071407;signaling#GO:0023052;response to steroid hormone#GO:0048545 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=21403|UniProtKB=Q5TEZ5 Q5TEZ5 C6orf163 PTHR34645:SF1 SIMILAR TO HYPOTHETICAL PROTEIN SIMILAR TO HYPOTHETICAL PROTEIN HUMAN|HGNC=29299|UniProtKB=Q9P217 Q9P217 ZSWIM5 PTHR22619:SF2 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 5 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;axonogenesis#GO:0007409;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular component organization#GO:0016043;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;regulation of locomotion#GO:0040012;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;regulation of chemotaxis#GO:0050920;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;regulation of response to external stimulus#GO:0032101;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;generation of neurons#GO:0048699 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234 HUMAN|HGNC=27102|UniProtKB=Q86Y91 Q86Y91 KIF18B PTHR24115:SF414 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF18B pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;ATP-dependent microtubule motor activity, plus-end-directed#GO:0008574;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 nuclear chromosome segregation#GO:0098813;protein-containing complex disassembly#GO:0032984;cellular protein complex disassembly#GO:0043624;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;microtubule depolymerization#GO:0007019;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;cellular component disassembly#GO:0022411;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;supramolecular fiber organization#GO:0097435;movement of cell or subcellular component#GO:0006928;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;mitotic sister chromatid segregation#GO:0000070;protein-containing complex subunit organization#GO:0043933 supramolecular complex#GO:0099080;spindle midzone#GO:0051233;spindle microtubule#GO:0005876;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle midzone#GO:1990023;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=12998|UniProtKB=O43670 O43670 ZNF207 PTHR23215:SF1 ZINC FINGER PROTEIN 207 BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 negative regulation of sister chromatid segregation#GO:0033046;cellular component biogenesis#GO:0044085;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of mitotic sister chromatid segregation#GO:0033047;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;attachment of spindle microtubules to kinetochore#GO:0008608;spindle organization#GO:0007051;negative regulation of cellular component organization#GO:0051129;cellular component assembly#GO:0022607;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;mitotic spindle organization#GO:0007052;mitotic cell cycle phase transition#GO:0044772;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;negative regulation of organelle organization#GO:0010639;mitotic spindle assembly#GO:0090307;mitotic spindle assembly checkpoint#GO:0007094;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;mitotic cell cycle checkpoint#GO:0007093;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;organelle assembly#GO:0070925;metaphase/anaphase transition of cell cycle#GO:0044784;negative regulation of chromosome separation#GO:1905819;microtubule-based process#GO:0007017;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular#GO:0005622;chromosome, centromeric region#GO:0000775;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=26921|UniProtKB=Q2NL67 Q2NL67 PARP6 PTHR21328:SF23 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP6 protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;transferase activity, transferring glycosyl groups#GO:0016757;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;kinase activator activity#GO:0019209;protein kinase activity#GO:0004672;protein kinase activator activity#GO:0030295;transferase activity#GO:0016740;protein serine/threonine kinase activator activity#GO:0043539;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;transferase activity, transferring pentosyl groups#GO:0016763;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;response to unfolded protein#GO:0006986;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to topologically incorrect protein#GO:0035967;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;cellular response to unfolded protein#GO:0034620;biological regulation#GO:0065007;cellular response to stress#GO:0033554 envelope#GO:0031975;endoplasmic reticulum tubular network#GO:0071782;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=2265|UniProtKB=P13073 P13073 COX4I1 PTHR10707:SF12 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 1, MITOCHONDRIAL ribonucleoside triphosphate metabolic process#GO:0009199;nucleoside triphosphate metabolic process#GO:0009141;ATP biosynthetic process#GO:0006754;proton transmembrane transport#GO:1902600;inorganic cation transmembrane transport#GO:0098662;purine nucleotide biosynthetic process#GO:0006164;ATP synthesis coupled electron transport#GO:0042773;electron transport chain#GO:0022900;inorganic ion transmembrane transport#GO:0098660;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide biosynthetic process#GO:0009165;ATP metabolic process#GO:0046034;establishment of localization#GO:0051234;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;purine ribonucleoside triphosphate metabolic process#GO:0009205;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular nitrogen compound metabolic process#GO:0034641;ion transmembrane transport#GO:0034220;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;transport#GO:0006810;aerobic electron transport chain#GO:0019646;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;cation transport#GO:0006812;phosphorus metabolic process#GO:0006793;cation transmembrane transport#GO:0098655;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;respiratory electron transport chain#GO:0022904;phosphorylation#GO:0016310;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;cellular respiration#GO:0045333;heterocycle metabolic process#GO:0046483;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;localization#GO:0051179;mitochondrial ATP synthesis coupled electron transport#GO:0042775;ATP synthesis coupled proton transport#GO:0015986;oxidative phosphorylation#GO:0006119;energy coupled proton transport, down electrochemical gradient#GO:0015985;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex IV#GO:0045277 oxidase#PC00175 HUMAN|HGNC=29615|UniProtKB=Q86SG7 Q86SG7 LYG2 PTHR31698:SF4 LYSOZYME G FAMILY MEMBER LYSOZYME G-LIKE PROTEIN 2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=8568|UniProtKB=P09958 P09958 FURIN PTHR42884:SF1 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 serine protease#PC00203 Endothelin signaling pathway#P00019>furin#P00575;Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 HUMAN|HGNC=8008|UniProtKB=Q9ULB1 Q9ULB1 NRXN1 PTHR15036:SF51 PIKACHURIN-LIKE PROTEIN NEUREXIN-1 HUMAN|HGNC=48661|UniProtKB=E5RQL4 E5RQL4 FTCDNL1 PTHR12234:SF1 FORMIMINOTRANSFERASE-CYCLODEAMINASE FORMIMINOTRANSFERASE N-TERMINAL SUBDOMAIN-CONTAINING PROTEIN HUMAN|HGNC=16832|UniProtKB=Q16864 Q16864 ATP6V1F PTHR13861:SF2 VACUOLAR ATP SYNTHASE SUBUNIT F V-TYPE PROTON ATPASE SUBUNIT F pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ion transmembrane transporter activity#GO:0015075;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887;active ion transmembrane transporter activity#GO:0022853 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002 HUMAN|HGNC=20144|UniProtKB=Q86VK4 Q86VK4 ZNF410 PTHR46179:SF3 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 410 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=28381|UniProtKB=Q8NHP6 Q8NHP6 MOSPD2 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=5246|UniProtKB=P04792 P04792 HSPB1 PTHR45640:SF7 HEAT SHOCK PROTEIN HSP-12.2-RELATED HEAT SHOCK PROTEIN BETA-1 CCKR signaling map#P06959>HSP27#P07154;VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231;p38 MAPK pathway#P05918>HSP27#P06016 HUMAN|HGNC=11374|UniProtKB=O76061 O76061 STC2 PTHR11245:SF2 STANNIOCALCIN STANNIOCALCIN-2 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;metal ion homeostasis#GO:0055065 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 HUMAN|HGNC=28607|UniProtKB=Q8N6M8 Q8N6M8 IQCF1 PTHR21633:SF14 IQ MOTIF CONTAINING F IQ DOMAIN-CONTAINING PROTEIN F1 protein binding#GO:0005515;calmodulin binding#GO:0005516;binding#GO:0005488 HUMAN|HGNC=26976|UniProtKB=Q96DE5 Q96DE5 ANAPC16 PTHR31564:SF0 ANAPHASE-PROMOTING COMPLEX SUBUNIT 16 ANAPHASE-PROMOTING COMPLEX SUBUNIT 16 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 supramolecular complex#GO:0099080;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234;chromosome, centromeric region#GO:0000775;cytosol#GO:0005829;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687 HUMAN|HGNC=18247|UniProtKB=Q2TAY7 Q2TAY7 SMU1 PTHR22848:SF2 WD40 REPEAT PROTEIN WD40 REPEAT-CONTAINING PROTEIN SMU1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=16898|UniProtKB=O43281 O43281 EFS PTHR10654:SF14 CAS SCAFFOLDING PROTEIN EMBRYONAL FYN-ASSOCIATED SUBSTRATE cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;actin cytoskeleton reorganization#GO:0031532;enzyme linked receptor protein signaling pathway#GO:0007167;localization of cell#GO:0051674;cell motility#GO:0048870;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;anchoring junction#GO:0070161;intracellular#GO:0005622;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=19875|UniProtKB=Q8NCW6 Q8NCW6 GALNT11 PTHR11675:SF10 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 11 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of Notch signaling pathway#GO:0008593;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signaling#GO:0023052;Notch signaling pathway#GO:0007219 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=12585|UniProtKB=P31930 P31930 UQCRC1 PTHR11851:SF116 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;mitochondrial protein processing#GO:0034982;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;establishment of protein localization#GO:0045184;protein processing#GO:0016485;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;protein localization to organelle#GO:0033365;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein processing involved in protein targeting to mitochondrion#GO:0006627;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 metalloprotease#PC00153 HUMAN|HGNC=7797|UniProtKB=P25963 P25963 NFKBIA PTHR46680:SF1 NF-KAPPA-B INHIBITOR ALPHA NF-KAPPA-B INHIBITOR ALPHA T cell activation#P00053>I kappa B#P01323;Toll pathway-drosophila#P06217>CACT#P06342;Toll receptor signaling pathway#P00054>IkappaB#P01338;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>NFkappaB#P00859;CCKR signaling map#P06959>IKBalpha#P07053;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IkappaB#P00857;Apoptosis signaling pathway#P00006>IkappaB#P00292;B cell activation#P00010>I kappa B#P00392 HUMAN|HGNC=29177|UniProtKB=Q7Z3U7 Q7Z3U7 MON2 PTHR10663:SF333 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PROTEIN MON2 HOMOLOG guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=10071|UniProtKB=O76064 O76064 RNF8 PTHR15067:SF4 E3 UBIQUITIN-PROTEIN LIGASE RNF8 E3 UBIQUITIN-PROTEIN LIGASE RNF8 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytosol#GO:0005829;cellular anatomical entity#GO:0110165 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=14106|UniProtKB=Q9HCU8 Q9HCU8 POLD4 PTHR14303:SF0 DNA POLYMERASE DELTA SUBUNIT 4 DNA POLYMERASE DELTA SUBUNIT 4 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;DNA polymerase activity#GO:0034061;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;DNA-dependent DNA replication#GO:0006261;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 pre-replicative complex#GO:0036387;intracellular membrane-bounded organelle#GO:0043231;epsilon DNA polymerase complex#GO:0008622;replisome#GO:0030894;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;replication fork#GO:0005657;membrane-enclosed lumen#GO:0031974;origin recognition complex#GO:0000808;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;DNA replication preinitiation complex#GO:0031261;catalytic complex#GO:1902494;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;CMG complex#GO:0071162;nuclear pre-replicative complex#GO:0005656;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 DNA-directed DNA polymerase#PC00018 HUMAN|HGNC=26148|UniProtKB=Q6UUV7 Q6UUV7 CRTC3 PTHR13589:SF4 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR 3 protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 HUMAN|HGNC=3262|UniProtKB=Q9UL18 Q9UL18 AGO1 PTHR22891:SF17 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-1 translation initiation factor#PC00224 HUMAN|HGNC=15822|UniProtKB=Q8N573 Q8N573 OXR1 PTHR23354:SF69 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED OXIDATION RESISTANCE PROTEIN 1 cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of neuron death#GO:1901214;regulation of response to stress#GO:0080134;neuron death#GO:0070997;response to oxidative stress#GO:0006979;negative regulation of neuron death#GO:1901215;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;response to stimulus#GO:0050896;regulation of cellular response to stress#GO:0080135;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;negative regulation of cellular process#GO:0048523 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=30690|UniProtKB=P0CG40 P0CG40 SP9 PTHR23235:SF26 KRUEPPEL-LIKE TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SP9 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=52413|UniProtKB=A0A1W2PPD8 A0A1W2PPD8 KDM4F PTHR10694:SF90 LYSINE-SPECIFIC DEMETHYLASE LYSINE DEMETHYLASE 4F 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=31303|UniProtKB=A6NCV1 A6NCV1 OR6C74 PTHR26454:SF72 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C74 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=12264|UniProtKB=A0JD37 A0JD37 TRDV3 PTHR23267:SF189 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR DELTA VARIABLE 3 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=4835|UniProtKB=P02008 P02008 HBZ PTHR11442:SF41 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT ZETA small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;intracellular#GO:0005622;extracellular region#GO:0005576 HUMAN|HGNC=30389|UniProtKB=Q96A65 Q96A65 EXOC4 PTHR14146:SF0 EXOCYST COMPLEX COMPONENT 4 EXOCYST COMPLEX COMPONENT 4 vesicle fusion#GO:0006906;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;secretion#GO:0046903;vesicle organization#GO:0016050;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein targeting to membrane#GO:0006612;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;exocytosis#GO:0006887;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;export from cell#GO:0140352 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 membrane traffic protein#PC00150 HUMAN|HGNC=21290|UniProtKB=Q6ISU1 Q6ISU1 PTCRA PTHR37866:SF1 PRE T-CELL ANTIGEN RECEPTOR ALPHA PRE T-CELL ANTIGEN RECEPTOR ALPHA HUMAN|HGNC=22224|UniProtKB=Q6ZMT4 Q6ZMT4 KDM7A PTHR23123:SF15 PHD/F-BOX CONTAINING PROTEIN LYSINE-SPECIFIC DEMETHYLASE 7A molecular function regulator#GO:0098772;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;protein modification process#GO:0036211;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;demethylation#GO:0070988;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein demethylation#GO:0006482;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=4018|UniProtKB=Q11130 Q11130 FUT7 PTHR11929:SF12 ALPHA- 1,3 -FUCOSYLTRANSFERASE ALPHA-(1,3)-FUCOSYLTRANSFERASE 7 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824 glycosylation#GO:0070085;metabolic process#GO:0008152 glycosyltransferase#PC00111 HUMAN|HGNC=29066|UniProtKB=Q9UKJ3 Q9UKJ3 GPATCH8 PTHR17614:SF11 ZINC FINGER-CONTAINING G PATCH DOMAIN-CONTAINING PROTEIN 8 HUMAN|HGNC=4226|UniProtKB=P31150 P31150 GDI1 PTHR11787:SF3 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR ALPHA GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 G-protein modulator#PC00022 HUMAN|HGNC=11125|UniProtKB=P61956 P61956 SUMO2 PTHR10562:SF74 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 2 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 p53 pathway#P00059>Sumo-1 ligase#P04635 HUMAN|HGNC=29012|UniProtKB=O15054 O15054 KDM6B PTHR14017:SF5 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 6B cis-regulatory region sequence-specific DNA binding#GO:0000987;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;demethylase activity#GO:0032451;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;catalytic activity, acting on a protein#GO:0140096 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=28786|UniProtKB=Q7Z5U6 Q7Z5U6 WDR53 PTHR44666:SF1 WD REPEAT-CONTAINING PROTEIN 53 WD REPEAT-CONTAINING PROTEIN 53 HUMAN|HGNC=18316|UniProtKB=Q8N895 Q8N895 ZNF366 PTHR24390:SF38 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 366 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;organic cyclic compound binding#GO:0097159;transcription corepressor activity#GO:0003714;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=19691|UniProtKB=Q9BV79 Q9BV79 MECR PTHR43981:SF2 ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor#GO:0016628 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 reductase#PC00198 HUMAN|HGNC=29588|UniProtKB=Q5BJE1 Q5BJE1 CCDC178 PTHR35088:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 178 COILED-COIL DOMAIN-CONTAINING PROTEIN 178 HUMAN|Gene=YV020_HUMAN|UniProtKB=Q8N402 Q8N402 - PTHR22534:SF5 UNCHARACTERIZED IMD DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=23535|UniProtKB=Q96MN9 Q96MN9 ZNF488 PTHR16516:SF5 AGAP007109-PA ZINC FINGER PROTEIN 488 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8506|UniProtKB=P13725 P13725 OSM PTHR14261:SF0 ONCOSTATIN M ONCOSTATIN-M interleukin superfamily#PC00128 HUMAN|HGNC=13611|UniProtKB=Q9NXK8 Q9NXK8 FBXL12 PTHR16134:SF3 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX/LRR-REPEAT PROTEIN 12 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=10933|UniProtKB=Q9NRA2 Q9NRA2 SLC17A5 PTHR11662:SF399 SOLUTE CARRIER FAMILY 17 SIALIN secondary carrier transporter#PC00258 HUMAN|HGNC=15258|UniProtKB=Q8NGF4 Q8NGF4 OR5AP2 PTHR48018:SF21 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AP2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=15734|UniProtKB=Q96J84 Q96J84 KIRREL1 PTHR11640:SF14 NEPHRIN KIN OF IRRE-LIKE PROTEIN 1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=8702|UniProtKB=Q9Y5G9 Q9Y5G9 PCDHGA4 PTHR24028:SF94 CADHERIN-87A PROTOCADHERIN GAMMA-A4 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 HUMAN|HGNC=28750|UniProtKB=Q1EHB4 Q1EHB4 SLC5A12 PTHR42985:SF15 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 2 symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;sodium ion transport#GO:0006814;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812 secondary carrier transporter#PC00258 HUMAN|HGNC=4272|UniProtKB=Q9Y2X7 Q9Y2X7 GIT1 PTHR46097:SF1 G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP ARF GTPASE-ACTIVATING PROTEIN GIT1 HUMAN|HGNC=17258|UniProtKB=Q9UPW5 Q9UPW5 AGTPBP1 PTHR12756:SF24 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 1 C-terminal protein amino acid modification#GO:0018410;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;post-translational protein modification#GO:0043687;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metalloprotease#PC00153 HUMAN|HGNC=12787|UniProtKB=P56706 P56706 WNT7B PTHR12027:SF73 WNT RELATED PROTEIN WNT-7B receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cellular response to stress#GO:0080135;regulation of JNK cascade#GO:0046328;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;stress-activated MAPK cascade#GO:0051403;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;JNK cascade#GO:0007254;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cell fate commitment#GO:0045165;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of JNK cascade#GO:0046330;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;positive regulation of stress-activated MAPK cascade#GO:0032874;protein metabolic process#GO:0019538;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;regulation of stress-activated protein kinase signaling cascade#GO:0070302;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;multicellular organism development#GO:0007275;regulation of response to stress#GO:0080134;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of stress-activated MAPK cascade#GO:0032872;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;generation of neurons#GO:0048699;positive regulation of stress-activated protein kinase signaling cascade#GO:0070304 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=21868|UniProtKB=Q9GZY4 Q9GZY4 COA1 PTHR47148:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 chaperone#PC00072 HUMAN|HGNC=33704|UniProtKB=Q66K66 Q66K66 TMEM198 PTHR31247:SF7 TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER TRANSMEMBRANE PROTEIN 198 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of Wnt signaling pathway#GO:0030177;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=19417|UniProtKB=Q494X3 Q494X3 ZNF404 PTHR24381:SF53 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 404 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4749|UniProtKB=Q99877 Q99877 H2BC15 PTHR23428:SF314 HISTONE H2B HISTONE H2B TYPE 1-N nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chromatin assembly or disassembly#GO:0006333;cellular protein-containing complex assembly#GO:0034622;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;cellular process#GO:0009987;protein-DNA complex assembly#GO:0065004;DNA conformation change#GO:0071103;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 histone#PC00118 HUMAN|HGNC=23760|UniProtKB=Q9H6B9 Q9H6B9 EPHX3 PTHR43329:SF10 EPOXIDE HYDROLASE EPOXIDE HYDROLASE 3 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=21211|UniProtKB=Q9BWV7 Q9BWV7 TTLL2 PTHR12241:SF118 TUBULIN POLYGLUTAMYLASE TUBULIN POLYGLUTAMYLASE TTLL2-RELATED cytoskeletal protein binding#GO:0008092;ligase activity#GO:0016874;protein binding#GO:0005515;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;nitrogen compound metabolic process#GO:0006807;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=24864|UniProtKB=O14556 O14556 GAPDHS PTHR10836:SF79 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, TESTIS-SPECIFIC oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;purine ribonucleoside diphosphate metabolic process#GO:0009179;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810 HUMAN|HGNC=29488|UniProtKB=Q9H3K6 Q9H3K6 BOLA2B PTHR12735:SF42 BOLA-LIKE PROTEIN-RELATED BOLA-LIKE PROTEIN 2 metal cluster binding#GO:0051540;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular cation homeostasis#GO:0030003;transition metal ion homeostasis#GO:0055076;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular homeostasis#GO:0019725;cellular iron ion homeostasis#GO:0006879;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;iron ion homeostasis#GO:0055072;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=37176|UniProtKB=A6NCW7 A6NCW7 USP17L4 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=14770|UniProtKB=Q8NGN7 Q8NGN7 OR10D4P PTHR26453:SF19 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10D4-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=19142|UniProtKB=Q96QH8 Q96QH8 SPACA5B PTHR11407:SF31 LYSOZYME C SPERM ACROSOME-ASSOCIATED PROTEIN 5 HUMAN|HGNC=26168|UniProtKB=Q9H6L4 Q9H6L4 ARMC7 PTHR46263:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 7 ARMADILLO REPEAT-CONTAINING PROTEIN 7 HUMAN|HGNC=3211|UniProtKB=P29692 P29692 EEF1D PTHR11595:SF54 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-DELTA GTPase binding#GO:0051020;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation elongation factor#PC00222 HUMAN|HGNC=18470|UniProtKB=Q9NYG2 Q9NYG2 ZDHHC3 PTHR22883:SF246 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC3 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein palmitoylation#GO:0018345;protein metabolic process#GO:0019538;protein lipidation#GO:0006497;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;peptide transport#GO:0015833;cellular process#GO:0009987;lipoprotein biosynthetic process#GO:0042158;primary metabolic process#GO:0044238;protein localization#GO:0008104;cellular protein modification process#GO:0006464;localization#GO:0051179;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;lipoprotein metabolic process#GO:0042157;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=13380|UniProtKB=Q9BY19 Q9BY19 MS4A8 PTHR23320:SF155 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 8 transporter#PC00227 HUMAN|HGNC=25820|UniProtKB=Q9C0D3 Q9C0D3 ZYG11B PTHR12904:SF21 FAMILY NOT NAMED PROTEIN ZYG-11 HOMOLOG B protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=2201|UniProtKB=P02461 P02461 COL3A1 PTHR24023:SF604 COLLAGEN ALPHA COLLAGEN ALPHA-1(III) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=31949|UniProtKB=A8MTB9 A8MTB9 CEACAM18 PTHR44337:SF10 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 18 HUMAN|HGNC=13300|UniProtKB=Q9BZJ8 Q9BZJ8 GPR61 PTHR22752:SF5 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 61 G-protein coupled receptor#PC00021 HUMAN|HGNC=15847|UniProtKB=P82980 P82980 RBP5 PTHR11955:SF74 FATTY ACID BINDING PROTEIN RETINOL-BINDING PROTEIN 5 HUMAN|HGNC=12013|UniProtKB=P67936 P67936 TPM4 PTHR19269:SF70 TROPOMYOSIN TROPOMYOSIN ALPHA-4 CHAIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 HUMAN|HGNC=12636|UniProtKB=O95399 O95399 UTS2 PTHR14447:SF0 UROTENSIN 2 UROTENSIN-2 HUMAN|HGNC=9016|UniProtKB=P08F94 P08F94 PKHD1 PTHR46769:SF1 POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1 FIBROCYSTIN HUMAN|HGNC=32258|UniProtKB=A6NDY2 A6NDY2 FAM90A10P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=21087|UniProtKB=Q7Z6A9 Q7Z6A9 BTLA PTHR37996:SF1 B- AND T-LYMPHOCYTE ATTENUATOR B- AND T-LYMPHOCYTE ATTENUATOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 immune response-regulating signaling pathway#GO:0002764;immune response-regulating cell surface receptor signaling pathway#GO:0002768;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;immune response#GO:0006955;regulation of immune response#GO:0050776;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=10397|UniProtKB=P08708 P08708 RPS17 PTHR10732:SF14 40S RIBOSOMAL PROTEIN S17 40S RIBOSOMAL PROTEIN S17 ribosomal protein#PC00202 HUMAN|HGNC=15310|UniProtKB=Q8N0Y5 Q8N0Y5 OR8I2 PTHR48018:SF73 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8I2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=19971|UniProtKB=Q96G25 Q96G25 MED8 PTHR13074:SF9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 general transcription factor#PC00259 HUMAN|HGNC=2065|UniProtKB=Q96NY7 Q96NY7 CLIC6 PTHR45476:SF1 CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6-RELATED CHLORIDE INTRACELLULAR CHANNEL PROTEIN 6 ion channel#PC00133 Nicotine pharmacodynamics pathway#P06587>CLIC6#P06611;Dopamine receptor mediated signaling pathway#P05912>CLIC6#P05968 HUMAN|HGNC=4234|UniProtKB=P55040 P55040 GEM PTHR45775:SF4 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C GTP-BINDING PROTEIN GEM carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;transporter activity#GO:0005215;channel activity#GO:0015267;calcium channel regulator activity#GO:0005246;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;channel regulator activity#GO:0016247;anion binding#GO:0043168 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|Ensembl=ENSG00000282872|UniProtKB=A0A0U1RR37 A0A0U1RR37 C1orf232 PTHR35663:SF3 TESTIS DEVELOPMENT-RELATED PROTEIN-RELATED GENE, 30191-RELATED HUMAN|HGNC=20040|UniProtKB=Q01518 Q01518 CAP1 PTHR10652:SF1 ADENYLYL CYCLASE-ASSOCIATED PROTEIN ADENYLYL CYCLASE-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;enzyme binding#GO:0019899;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 regulation of lyase activity#GO:0051339;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular process#GO:0009987;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;intracellular signal transduction#GO:0035556;cAMP-mediated signaling#GO:0019933;signaling#GO:0023052;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=4486|UniProtKB=O00270 O00270 GPR31 PTHR46048:SF7 HYDROXYCARBOXYLIC ACID RECEPTOR 2 12-(S)-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID RECEPTOR HUMAN|HGNC=1603|UniProtKB=P41597 P41597 CCR2 PTHR10489:SF913 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 2 response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response#GO:0006952;immune response#GO:0006955;inflammatory response#GO:0006954 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=18452|UniProtKB=Q8ND25 Q8ND25 ZNRF1 PTHR46661:SF2 E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZNRF1 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=19113|UniProtKB=P59538 P59538 TAS2R31 PTHR11394:SF129 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 31 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=30166|UniProtKB=Q502X0 Q502X0 MORN2 PTHR46917:SF1 MORN REPEAT-CONTAINING PROTEIN 2 MORN REPEAT-CONTAINING PROTEIN 2 HUMAN|HGNC=21316|UniProtKB=Q6UB99 Q6UB99 ANKRD11 PTHR24145:SF3 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 11 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 11 anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;developmental process#GO:0032502 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=24929|UniProtKB=Q969U7 Q969U7 PSMG2 PTHR12970:SF1 PROTEASOME ASSEMBLY CHAPERONE 2 PROTEASOME ASSEMBLY CHAPERONE 2 proteasome assembly#GO:0043248;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chaperone#PC00072 HUMAN|HGNC=10073|UniProtKB=O60942 O60942 RNGTT PTHR10367:SF17 MRNA-CAPPING ENZYME MRNA-CAPPING ENZYME transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 mRNA capping factor#PC00145 HUMAN|HGNC=1300|UniProtKB=P58505 P58505 C21orf58 PTHR28604:SF2 FAMILY NOT NAMED RIKEN CDNA 2610028H24 GENE HUMAN|HGNC=17859|UniProtKB=Q5SRE5 Q5SRE5 NUP188 PTHR31431:SF1 NUCLEOPORIN NUP188 HOMOLOG NUCLEOPORIN NUP188 HOMOLOG structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=33845|UniProtKB=P0CL85 P0CL85 STAG3L3 PTHR11199:SF8 STROMAL ANTIGEN COHESIN SUBUNIT SA-3-RELATED binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;organelle organization#GO:0006996;chromosome organization#GO:0051276;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;chromosome segregation#GO:0007059 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;chromatin#GO:0000785;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=7931|UniProtKB=O75607 O75607 NPM3 PTHR22747:SF13 NUCLEOPLASMIN NUCLEOPLASMIN-3 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;histone binding#GO:0042393 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chaperone#PC00072 HUMAN|HGNC=26670|UniProtKB=A2RUB1 A2RUB1 MEIOC PTHR33861:SF3 PROTEIN CBG18333 MEIOSIS-SPECIFIC COILED-COIL DOMAIN-CONTAINING PROTEIN MEIOC negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;male gamete generation#GO:0048232;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;gene expression#GO:0010467;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;M phase#GO:0000279;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;male meiotic nuclear division#GO:0007140;multi-organism reproductive process#GO:0044703;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;meiosis I#GO:0007127;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;meiosis I cell cycle phase#GO:0098764;gamete generation#GO:0007276;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA catabolic process#GO:0061013;RNA metabolic process#GO:0016070;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;meiotic cell cycle process#GO:1903046;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of gene expression#GO:0010468;cell cycle phase#GO:0022403;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;multicellular organism reproduction#GO:0032504;negative regulation of cellular catabolic process#GO:0031330;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;multi-organism process#GO:0051704;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cell cycle#GO:0007049;biological phase#GO:0044848;organelle fission#GO:0048285;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17383|UniProtKB=Q9H3N8 Q9H3N8 HRH4 PTHR24247:SF199 5-HYDROXYTRYPTAMINE RECEPTOR HISTAMINE H4 RECEPTOR cation binding#GO:0043169;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;binding#GO:0005488;organic cyclic compound binding#GO:0097159;acetylcholine receptor activity#GO:0015464;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;heterocyclic compound binding#GO:1901363;acetylcholine binding#GO:0042166;ion binding#GO:0043167;G protein-coupled receptor activity#GO:0004930;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;negative regulation of intracellular signal transduction#GO:1902532;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;defense response#GO:0006952;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;negative regulation of catalytic activity#GO:0043086;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935;negative regulation of molecular function#GO:0044092 synapse#GO:0045202;somatodendritic compartment#GO:0036477;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 HUMAN|HGNC=2359|UniProtKB=Q9NZV1 Q9NZV1 CRIM1 PTHR46439:SF1 CYSTEINE-RICH MOTOR NEURON 1 PROTEIN CYSTEINE-RICH MOTOR NEURON 1 PROTEIN HUMAN|HGNC=6401|UniProtKB=Q92973 Q92973 TNPO1 PTHR10527:SF21 IMPORTIN BETA TRANSPORTIN-1 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=28675|UniProtKB=Q86XK7 Q86XK7 VSIG1 PTHR44974:SF1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=26203|UniProtKB=Q6UXY1 Q6UXY1 BAIAP2L2 PTHR14206:SF5 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2-LIKE PROTEIN 2 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;actin cytoskeleton reorganization#GO:0031532;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=929|UniProtKB=Q9UBX8 Q9UBX8 B4GALT6 PTHR19300:SF47 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 6 glycosyltransferase#PC00111 HUMAN|HGNC=23226|UniProtKB=Q9BX82 Q9BX82 ZNF471 PTHR24377:SF951 IP01015P-RELATED ZINC FINGER PROTEIN 471 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11070|UniProtKB=P57103 P57103 SLC8A3 PTHR11878:SF7 SODIUM/CALCIUM EXCHANGER SODIUM/CALCIUM EXCHANGER 3 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;cation:cation antiporter activity#GO:0015491;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;solute:cation antiporter activity#GO:0015298;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;sodium ion transport#GO:0006814;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725 synapse#GO:0045202;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;sarcolemma#GO:0042383;axon#GO:0030424;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=15527|UniProtKB=Q86Z14 Q86Z14 KLB PTHR10353:SF68 GLYCOSYL HYDROLASE BETA-KLOTHO glucosidase activity#GO:0015926;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;growth factor receptor binding#GO:0070851;fibroblast growth factor binding#GO:0017134;growth factor binding#GO:0019838;protein binding#GO:0005515;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 response to organic substance#GO:0010033;fibroblast growth factor receptor signaling pathway#GO:0008543;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;enzyme linked receptor protein signaling pathway#GO:0007167;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 glycosidase#PC00110 HUMAN|HGNC=1976|UniProtKB=O60543 O60543 CIDEA PTHR12306:SF8 CELL DEATH ACTIVATOR CIDE CELL DEATH ACTIVATOR CIDE-A regulation of biological process#GO:0050789;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of programmed cell death#GO:0043067 HUMAN|HGNC=16853|UniProtKB=O94829 O94829 IPO13 PTHR12363:SF33 TRANSPORTIN 3 AND IMPORTIN 13 IMPORTIN-13 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=29989|UniProtKB=Q86YP4 Q86YP4 GATAD2A PTHR13455:SF3 TRANSCRIPTIONAL REPRESSOR P66-RELATED TRANSCRIPTIONAL REPRESSOR P66-ALPHA sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=24745|UniProtKB=Q8NA69 Q8NA69 TEX45 PTHR34828:SF1 TESTIS-EXPRESSED PROTEIN 45 TESTIS-EXPRESSED PROTEIN 45 HUMAN|HGNC=31700|UniProtKB=A1YPR0 A1YPR0 ZBTB7C PTHR46105:SF7 AGAP004733-PA ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 7C cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=5821|UniProtKB=A0A075B6H7 A0A075B6H7 IGKV3-7 PTHR23267:SF331 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=30502|UniProtKB=Q6UWQ5 Q6UWQ5 LYZL1 PTHR11407:SF62 LYSOZYME C LYSOZYME-LIKE PROTEIN 1 HUMAN|HGNC=700|UniProtKB=P27540 P27540 ARNT PTHR23042:SF50 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 Hypoxia response via HIF activation#P00030>HIF-1beta#P00820 HUMAN|HGNC=10312|UniProtKB=P84098 P84098 RPL19 PTHR10722:SF34 60S RIBOSOMAL PROTEIN L19 60S RIBOSOMAL PROTEIN L19 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=37471|UniProtKB=P0CW00 P0CW00 TSPY8 PTHR11875:SF12 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED PROTEIN 1-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|Ensembl=ENSG00000263264|UniProtKB=A0A5F9ZHI8 A0A5F9ZHI8 ENSG00000263264 PTHR47440:SF1 RIKEN CDNA A430078G23 GENE RHO/RAC GUANINE NUCLEOTIDE EXCHANGE FACTOR 18 HUMAN|HGNC=5423|UniProtKB=P01563 P01563 IFNA2 PTHR11691:SF70 TYPE I INTERFERON INTERFERON ALPHA-2 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=25924|UniProtKB=Q96K31 Q96K31 C8orf76 PTHR31919:SF1 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 homeodomain transcription factor#PC00119 HUMAN|HGNC=615|UniProtKB=Q13790 Q13790 APOF PTHR15011:SF3 APOLIPOPROTEIN F APOLIPOPROTEIN F sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;cholesterol metabolic process#GO:0008203;secondary alcohol metabolic process#GO:1902652;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 apolipoprotein#PC00052 HUMAN|HGNC=25781|UniProtKB=Q96C12 Q96C12 ARMC5 PTHR23312:SF8 ARMC5 ARMADILLO REPEAT-CONTAINING -RELATED ARMADILLO REPEAT-CONTAINING PROTEIN 5 HUMAN|HGNC=10987|UniProtKB=O43808 O43808 SLC25A17 PTHR45939:SF5 PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED PEROXISOMAL MEMBRANE PROTEIN PMP34 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;cation transmembrane transporter activity#GO:0008324;ATP transmembrane transporter activity#GO:0005347;organophosphate ester transmembrane transporter activity#GO:0015605;ion transmembrane transporter activity#GO:0015075;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleotide transmembrane transporter activity#GO:0015215;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;microbody membrane#GO:0031903;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;integral component of peroxisomal membrane#GO:0005779;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777 HUMAN|HGNC=20788|UniProtKB=Q6PJF5 Q6PJF5 RHBDF2 PTHR45965:SF2 INACTIVE RHOMBOID PROTEIN INACTIVE RHOMBOID PROTEIN 2 signal transduction#GO:0007165;macromolecule localization#GO:0033036;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;protein secretion#GO:0009306;regulation of localization#GO:0032879;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of secretion#GO:0051046;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of protein transport#GO:0051223;signaling#GO:0023052;regulation of protein localization#GO:0032880;secretion by cell#GO:0032940;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;epidermal growth factor receptor signaling pathway#GO:0007173;regulation of protein secretion#GO:0050708;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;peptide transport#GO:0015833;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;protein localization#GO:0008104;localization#GO:0051179;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;establishment of protein localization to extracellular region#GO:0035592;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 serine protease#PC00203 HUMAN|HGNC=22986|UniProtKB=Q8IZC6 Q8IZC6 COL27A1 PTHR24023:SF844 COLLAGEN ALPHA COLLAGEN ALPHA-1(XXVII) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular component organization or biogenesis#GO:0071840;extracellular structure organization#GO:0043062;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 supramolecular complex#GO:0099080;extracellular matrix#GO:0031012;protein-containing complex#GO:0032991;basement membrane#GO:0005604;extracellular region#GO:0005576;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;collagen-containing extracellular matrix#GO:0062023;supramolecular polymer#GO:0099081 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=7600|UniProtKB=O00160 O00160 MYO1F PTHR13140:SF663 MYOSIN UNCONVENTIONAL MYOSIN-IF pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;actin filament binding#GO:0051015;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;actin binding#GO:0003779;ATPase activity#GO:0016887 cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;transport#GO:0006810;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;establishment of localization in cell#GO:0051649;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;actin cytoskeleton organization#GO:0030036;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 microvillus#GO:0005902;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=13281|UniProtKB=B1AK53 B1AK53 ESPN PTHR24153:SF14 ESPIN ESPIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament bundle organization#GO:0061572 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-motor actin binding protein#PC00165 HUMAN|HGNC=33279|UniProtKB=P0C7T5 P0C7T5 ATXN1L PTHR13392:SF6 ATAXIN 1 ATAXIN-1-LIKE cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2080|UniProtKB=P54105 P54105 CLNS1A PTHR21399:SF3 CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN METHYLOSOME SUBUNIT PICLN transporter#PC00227 HUMAN|HGNC=4200|UniProtKB=P78537 P78537 BLOC1S1 PTHR13073:SF0 BLOC-1 COMPLEX SUBUNIT 1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 1 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;BLOC-1 complex#GO:0031083;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 HUMAN|HGNC=1867|UniProtKB=P41208 P41208 CETN2 PTHR23050:SF305 CALCIUM BINDING PROTEIN CENTRIN-2 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle#GO:0007049;organelle fission#GO:0048285;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 calmodulin-related#PC00061 HUMAN|HGNC=12565|UniProtKB=Q13432 Q13432 UNC119 PTHR12951:SF5 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG A lipid binding#GO:0008289;binding#GO:0005488 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;organelle localization#GO:0051640;regulation of protein metabolic process#GO:0051246;nuclear division#GO:0000280;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;membrane invagination#GO:0010324;peptidyl-tyrosine phosphorylation#GO:0018108;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;cellular protein metabolic process#GO:0044267;establishment of organelle localization#GO:0051656;cilium assembly#GO:0060271;positive regulation of phosphorus metabolic process#GO:0010562;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;negative regulation of transport#GO:0051051;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection assembly#GO:0120031;regulation of phosphorylation#GO:0042325;regulation of receptor-mediated endocytosis#GO:0048259;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;cell division#GO:0051301;negative regulation of biological process#GO:0048519;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;microtubule cytoskeleton organization#GO:0000226;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;amide transport#GO:0042886;organic substance transport#GO:0071702;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;vesicle organization#GO:0016050;mitotic nuclear division#GO:0140014;protein localization to organelle#GO:0033365;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;cytokinesis#GO:0000910;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;membrane fission#GO:0090148;vesicle localization#GO:0051648;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;nervous system process#GO:0050877;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;positive regulation of protein metabolic process#GO:0051247;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;positive regulation of kinase activity#GO:0033674;cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;membrane organization#GO:0061024;system process#GO:0003008;positive regulation of cellular metabolic process#GO:0031325;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;regulation of vesicle-mediated transport#GO:0060627;establishment of protein localization#GO:0045184;regulation of phosphorus metabolic process#GO:0051174;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cytoskeleton-dependent cytokinesis#GO:0061640;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;regulation of endocytosis#GO:0030100;macromolecule metabolic process#GO:0043170;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;protein-containing complex localization#GO:0031503;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;transport#GO:0006810;developmental process#GO:0032502;peptidyl-amino acid modification#GO:0018193;mitotic cell cycle process#GO:1903047;mitotic cytokinesis#GO:0000281;regulation of transport#GO:0051049;positive regulation of metabolic process#GO:0009893;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;receptor-mediated endocytosis#GO:0006898;phosphorylation#GO:0016310;metabolic process#GO:0008152;multicellular organism development#GO:0007275;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;intraciliary transport involved in cilium assembly#GO:0035735;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;regulation of cellular protein metabolic process#GO:0032268;microtubule-based transport#GO:0099111;peptidyl-tyrosine modification#GO:0018212;positive regulation of protein kinase activity#GO:0045860;microtubule-based process#GO:0007017;vesicle budding from membrane#GO:0006900;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;sensory perception#GO:0007600;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 spindle midzone#GO:0051233;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=24175|UniProtKB=Q9P035 Q9P035 HACD3 PTHR11035:SF20 PTPLA DOMAIN PROTEIN VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 3 lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=1343|UniProtKB=O43734 O43734 TRAF3IP2 PTHR34257:SF2 ADAPTER PROTEIN CIKS ADAPTER PROTEIN CIKS regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;I-kappaB kinase/NF-kappaB signaling#GO:0007249;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;humoral immune response#GO:0006959;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 scaffold/adaptor protein#PC00226 HUMAN|HGNC=840|UniProtKB=P24539 P24539 ATP5PB PTHR12733:SF3 MITOCHONDRIAL ATP SYNTHASE B CHAIN ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL ATP synthase#PC00002 HUMAN|HGNC=29679|UniProtKB=Q9Y3D7 Q9Y3D7 PAM16 PTHR12388:SF0 MITOCHONDRIA ASSOCIATED GRANULOCYTE MACROPHAGE CSF SIGNALING MOLECULE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM16 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;mitochondrial transport#GO:0006839;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 transporter#PC00227 HUMAN|HGNC=19021|UniProtKB=Q8IWZ4 Q8IWZ4 TRIM48 PTHR24103:SF632 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 48 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=14237|UniProtKB=Q96NT3 Q96NT3 GUCD1 PTHR31400:SF1 GUANYLYL CYCLASE DOMAIN CONTAINING PROTEIN 1 GUCD1 PROTEIN GUCD1 guanylate cyclase#PC00114 HUMAN|HGNC=1837|UniProtKB=P53567 P53567 CEBPG PTHR23334:SF20 CCAAT/ENHANCER BINDING PROTEIN CCAAT/ENHANCER-BINDING PROTEIN GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=26383|UniProtKB=Q8N136 Q8N136 DAW1 PTHR44156:SF1 SUPERNUMERARY LIMBS, ISOFORM B-RELATED DYNEIN ASSEMBLY FACTOR WITH WDR REPEAT DOMAINS 1 HUMAN|HGNC=26965|UniProtKB=Q8WUK0 Q8WUK0 PTPMT1 PTHR46712:SF1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 HUMAN|HGNC=24860|UniProtKB=Q5MY95 Q5MY95 ENTPD8 PTHR11782:SF31 ADENOSINE/GUANOSINE DIPHOSPHATASE ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 8 nucleotide phosphatase#PC00173 HUMAN|HGNC=11440|UniProtKB=Q13190 Q13190 STX5 PTHR19957:SF3 SYNTAXIN SYNTAXIN-5 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;SNARE complex#GO:0031201;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 SNARE protein#PC00034 HUMAN|HGNC=15607|UniProtKB=Q14155 Q14155 ARHGEF7 PTHR46026:SF3 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 7 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=35422|UniProtKB=A8MQ27 A8MQ27 NEURL1B PTHR12429:SF10 NEURALIZED E3 UBIQUITIN-PROTEIN LIGASE NEURL1B ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;endocytosis#GO:0006897;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=26408|UniProtKB=Q96NL3 Q96NL3 ZNF599 PTHR24381:SF20 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 599 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3164|UniProtKB=O60869 O60869 EDF1 PTHR10245:SF15 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=9797|UniProtKB=P47224 P47224 RABIF PTHR13276:SF0 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 cation binding#GO:0043169;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;GTPase binding#GO:0051020;metal ion binding#GO:0046872;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;ion binding#GO:0043167;guanyl-nucleotide exchange factor activity#GO:0005085 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=28434|UniProtKB=Q8N1B3 Q8N1B3 CCNQ PTHR10026:SF70 CYCLIN CYCLIN-Q cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 kinase activator#PC00138 HUMAN|HGNC=9850|UniProtKB=Q9H6Z4 Q9H6Z4 RANBP3 PTHR23138:SF91 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;protein export from nucleus#GO:0006611;intracellular transport#GO:0046907;nuclear transport#GO:0051169 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=19866|UniProtKB=Q05BQ5 Q05BQ5 MBTD1 PTHR12247:SF79 POLYCOMB GROUP PROTEIN MBT DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;methylated histone binding#GO:0035064;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=37134|UniProtKB=A8MUZ8 A8MUZ8 ZNF705G PTHR24381:SF19 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 705G-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21592|UniProtKB=Q7Z5A7 Q7Z5A7 TAFA5 PTHR31878:SF0 CHEMOKINE-LIKE PROTEIN TAFA-5-RELATED CHEMOKINE-LIKE PROTEIN TAFA-5 chemokine#PC00074 HUMAN|HGNC=26367|UniProtKB=Q8N7G0 Q8N7G0 POU5F2 PTHR11636:SF14 POU DOMAIN POU DOMAIN, CLASS 5, TRANSCRIPTION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=10378|UniProtKB=P52815 P52815 MRPL12 PTHR45987:SF4 39S RIBOSOMAL PROTEIN L12 39S RIBOSOMAL PROTEIN L12, MITOCHONDRIAL ribosomal protein#PC00202 HUMAN|HGNC=9844|UniProtKB=O60895 O60895 RAMP2 PTHR14076:SF9 RECEPTOR ACTIVITY MODIFYING PROTEIN RAMP RECEPTOR ACTIVITY-MODIFYING PROTEIN 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular localization#GO:0051641;membrane organization#GO:0061024;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;anatomical structure morphogenesis#GO:0009653;membrane invagination#GO:0010324;establishment of localization#GO:0051234;tube morphogenesis#GO:0035239;divalent inorganic cation transport#GO:0072511;vasculature development#GO:0001944;organic substance metabolic process#GO:0071704;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;blood vessel morphogenesis#GO:0048514;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;tube development#GO:0035295;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;protein transport#GO:0015031;blood vessel development#GO:0001568;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;receptor internalization#GO:0031623;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;transport#GO:0006810;cation transport#GO:0006812;calcium ion transport#GO:0006816;amide transport#GO:0042886;system development#GO:0048731;organic substance transport#GO:0071702;divalent metal ion transport#GO:0070838;response to endogenous stimulus#GO:0009719;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;protein localization to plasma membrane#GO:0072659;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;cellular response to chemical stimulus#GO:0070887;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;ion transport#GO:0006811;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;localization#GO:0051179;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;biological regulation#GO:0065007 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991 transmembrane signal receptor#PC00197 HUMAN|HGNC=7854|UniProtKB=Q13287 Q13287 NMI PTHR15225:SF4 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN N-MYC-INTERACTOR cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=28275|UniProtKB=Q96AQ2 Q96AQ2 TMEM125 PTHR31416:SF1 TRANSMEMBRANE PROTEIN 125 TRANSMEMBRANE PROTEIN 125 HUMAN|HGNC=24950|UniProtKB=Q6UWP8 Q6UWP8 SBSN PTHR23243:SF3 SUPRABASAL-SPECIFIC PROTEIN SUPRABASIN SUPRABASIN HUMAN|HGNC=5218|UniProtKB=P26439 P26439 HSD3B2 PTHR10366:SF784 NAD DEPENDENT EPIMERASE/DEHYDRATASE 3 BETA-HYDROXYSTEROID DEHYDROGENASE/DELTA 5--4-ISOMERASE TYPE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091 HUMAN|HGNC=671|UniProtKB=P61587 P61587 RND3 PTHR24072:SF24 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOE GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 small GTPase#PC00208 Integrin signalling pathway#P00034>Rho#P00948 HUMAN|HGNC=30684|UniProtKB=O14907 O14907 TAX1BP3 PTHR23136:SF7 TAX1-BINDING PROTEIN 3-RELATED TAX1-BINDING PROTEIN 3 HUMAN|HGNC=6644|UniProtKB=P61968 P61968 LMO4 PTHR45787:SF5 LD11652P LIM DOMAIN TRANSCRIPTION FACTOR LMO4 HUMAN|HGNC=17393|UniProtKB=Q9H992 Q9H992 MARCHF7 PTHR14471:SF1 MARCH7/10 E3 UBIQUITIN PROTEIN LIGASE FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE MARCHF7 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=32687|UniProtKB=Q9P086 Q9P086 MED11 PTHR22890:SF2 UNCHARACTERIZED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=1478|UniProtKB=Q9UMQ6 Q9UMQ6 CAPN11 PTHR10183:SF322 CALPAIN CALPAIN-11 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 HUMAN|HGNC=14460|UniProtKB=Q9UN36 Q9UN36 NDRG2 PTHR11034:SF17 N-MYC DOWNSTREAM REGULATED PROTEIN NDRG2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 serine protease#PC00203 HUMAN|HGNC=11844|UniProtKB=Q9Y6L7 Q9Y6L7 TLL2 PTHR10127:SF866 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING TOLLOID-LIKE PROTEIN 2 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=16252|UniProtKB=Q8TC36 Q8TC36 SUN5 PTHR12911:SF44 SAD1/UNC-84-LIKE PROTEIN-RELATED SUN DOMAIN-CONTAINING PROTEIN 5 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;nucleus organization#GO:0006997;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;nuclear envelope organization#GO:0006998;cellular process#GO:0009987 envelope#GO:0031975;membrane protein complex#GO:0098796;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=23060|UniProtKB=P58005 P58005 SESN3 PTHR12474:SF4 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN-3 cation binding#GO:0043169;amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 regulation of catabolic process#GO:0009894;macroautophagy#GO:0016236;positive regulation of cellular metabolic process#GO:0031325;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;cell communication#GO:0007154;regulation of macroautophagy#GO:0016241;response to organonitrogen compound#GO:0010243;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;positive regulation of autophagy#GO:0010508;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;process utilizing autophagic mechanism#GO:0061919;response to endogenous stimulus#GO:0009719;cellular response to oxygen-containing compound#GO:1901701;positive regulation of metabolic process#GO:0009893;cellular response to starvation#GO:0009267;catabolic process#GO:0009056;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;TORC1 signaling#GO:0038202;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;regulation of autophagy#GO:0010506;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to amino acid starvation#GO:0034198 TORC2 complex#GO:0031932;cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 peroxidase#PC00180 HUMAN|HGNC=16817|UniProtKB=Q96DF8 Q96DF8 ESS2 PTHR12940:SF0 ES-2 PROTEIN - RELATED SPLICING FACTOR ESS-2 HOMOLOG catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=19320|UniProtKB=Q08708 Q08708 CD300C PTHR11860:SF102 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 6 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=22432|UniProtKB=Q9BWK5 Q9BWK5 CYREN PTHR14566:SF0 CELL CYCLE REGULATOR OF NON-HOMOLOGOUS END JOINING CELL CYCLE REGULATOR OF NON-HOMOLOGOUS END JOINING HUMAN|HGNC=25496|UniProtKB=Q9NW81 Q9NW81 DMAC2 PTHR13318:SF186 UNCHARACTERIZED DISTAL MEMBRANE-ARM ASSEMBLY COMPLEX PROTEIN 2 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=2297|UniProtKB=P48052 P48052 CPA2 PTHR11705:SF71 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A2 hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=26781|UniProtKB=Q8N112 Q8N112 LSMEM2 PTHR37333:SF1 LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 2 LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 2 HUMAN|HGNC=23517|UniProtKB=Q8N2H3 Q8N2H3 PYROXD2 PTHR10668:SF103 PHYTOENE DEHYDROGENASE PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 dehydrogenase#PC00092 HUMAN|HGNC=25654|UniProtKB=Q86YA3 Q86YA3 ZGRF1 PTHR10887:SF325 DNA2/NAM7 HELICASE FAMILY PROTEIN ZGRF1 HUMAN|HGNC=20922|UniProtKB=Q9BQ83 Q9BQ83 SLX1A PTHR20208:SF10 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;endodeoxyribonuclease activity#GO:0004520;deoxyribonuclease activity#GO:0004536 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 endodeoxyribonuclease#PC00093 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 HUMAN|HGNC=7670|UniProtKB=Q9Y6Q9 Q9Y6Q9 NCOA3 PTHR10684:SF3 NUCLEAR RECEPTOR COACTIVATOR NUCLEAR RECEPTOR COACTIVATOR 3 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor binding#GO:0016922;binding#GO:0005488;transcription coactivator activity#GO:0003713;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;nuclear receptor transcription coactivator activity#GO:0030374;molecular function regulator#GO:0098772;protein binding#GO:0005515;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102;DNA-binding transcription factor binding#GO:0140297 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;cellular response to hormone stimulus#GO:0032870;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 Gonadotropin-releasing hormone receptor pathway#P06664>Ncoa3#P06719 HUMAN|HGNC=15876|UniProtKB=Q96A57 Q96A57 TMEM230 PTHR15664:SF6 C20ORF30 PROTEIN TRANSMEMBRANE PROTEIN 230 HUMAN|HGNC=26025|UniProtKB=Q9NX47 Q9NX47 MARCHF5 PTHR46283:SF4 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 E3 UBIQUITIN-PROTEIN LIGASE MARCHF5 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=4699|UniProtKB=P46976 P46976 GYG1 PTHR11183:SF164 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN-1 transferase activity, transferring hexosyl groups#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity, transferring glycosyl groups#GO:0016757;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glucan metabolic process#GO:0044042;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;glycogen metabolic process#GO:0005977;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;glycogen biosynthetic process#GO:0005978;energy derivation by oxidation of organic compounds#GO:0015980;primary metabolic process#GO:0044238;cellular glucan metabolic process#GO:0006073;polysaccharide metabolic process#GO:0005976;glucan biosynthetic process#GO:0009250;cellular carbohydrate metabolic process#GO:0044262;oxidation-reduction process#GO:0055114;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;cellular polysaccharide biosynthetic process#GO:0033692;organic substance metabolic process#GO:0071704;cellular polysaccharide metabolic process#GO:0044264;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 glycosyltransferase#PC00111 HUMAN|HGNC=26700|UniProtKB=P0CG21 P0CG21 NHLRC4 PTHR25464:SF4 TRIPARTITE MOTIF-CONTAINING PROTEIN 2-LIKE PROTEIN NHL-REPEAT-CONTAINING PROTEIN 4 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein K48-linked ubiquitination#GO:0070936;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=24526|UniProtKB=Q6DD88 Q6DD88 ATL3 PTHR10751:SF32 GUANYLATE BINDING PROTEIN ATLASTIN-3 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;ion binding#GO:0043167;anion binding#GO:0043168 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 heterotrimeric G-protein#PC00117 HUMAN|HGNC=14449|UniProtKB=Q9UHM6 Q9UHM6 OPN4 PTHR24240:SF72 OPSIN MELANOPSIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to abiotic stimulus#GO:0071214;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=21154|UniProtKB=Q8WVZ7 Q8WVZ7 RNF133 PTHR22765:SF38 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF133 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=20455|UniProtKB=Q96EP1 Q96EP1 CHFR PTHR16079:SF4 UBIQUITIN LIGASE PROTEIN CHFR E3 UBIQUITIN-PROTEIN LIGASE CHFR ubiquitin-protein ligase#PC00234 HUMAN|HGNC=19883|UniProtKB=Q6ZSB9 Q6ZSB9 ZBTB49 PTHR24399:SF33 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 49 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11932|UniProtKB=Q9UNG2 Q9UNG2 TNFSF18 PTHR15267:SF1 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 18 TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 18 HUMAN|HGNC=9455|UniProtKB=O75360 O75360 PROP1 PTHR47409:SF1 HOMEOBOX PROTEIN PROPHET OF PIT-1 HOMEOBOX PROTEIN PROPHET OF PIT-1 homeodomain transcription factor#PC00119 HUMAN|HGNC=10982|UniProtKB=O75746 O75746 SLC25A12 PTHR45678:SF7 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;L-glutamate transmembrane transporter activity#GO:0005313;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 dicarboxylic acid transport#GO:0006835;organic acid transport#GO:0015849;transport#GO:0006810;nitrogen compound transport#GO:0071705;electron transport chain#GO:0022900;energy derivation by oxidation of organic compounds#GO:0015980;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;anion transport#GO:0006820;respiratory electron transport chain#GO:0022904;oxidation-reduction process#GO:0055114;mitochondrial transmembrane transport#GO:1990542;metabolic process#GO:0008152;cellular respiration#GO:0045333;L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;generation of precursor metabolites and energy#GO:0006091;ion transport#GO:0006811;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;mitochondrial transport#GO:0006839;localization#GO:0051179;C4-dicarboxylate transport#GO:0015740;organic acid transmembrane transport#GO:1903825 secondary carrier transporter#PC00258 HUMAN|HGNC=206|UniProtKB=Q9UKQ2 Q9UKQ2 ADAM28 PTHR11905:SF32 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 28 hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 metalloprotease#PC00153 HUMAN|HGNC=12978|UniProtKB=Q16670 Q16670 ZSCAN26 PTHR23226:SF56 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 26 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=53649|UniProtKB=A0A1W2PS18 A0A1W2PS18 PMIS2 PTHR14768:SF5 UPF0338 PROTEIN TRANSMEMBRANE PROTEIN PMIS2 HUMAN|HGNC=19992|UniProtKB=Q6U736 Q6U736 OPN5 PTHR24240:SF0 OPSIN OPSIN-5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;detection of stimulus#GO:0051606;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular response to abiotic stimulus#GO:0071214;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;regulation of cellular process#GO:0050794;response to radiation#GO:0009314;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;cellular response to light stimulus#GO:0071482 9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=18749|UniProtKB=Q13671 Q13671 RIN1 PTHR23101:SF62 RAB GDP/GTP EXCHANGE FACTOR RAS AND RAB INTERACTOR 1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=11448|UniProtKB=Q9P2R7 Q9P2R7 SUCLA2 PTHR11815:SF14 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;energy derivation by oxidation of organic compounds#GO:0015980;phosphorus metabolic process#GO:0006793;tricarboxylic acid cycle#GO:0006099;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;acyl-CoA metabolic process#GO:0006637;generation of precursor metabolites and energy#GO:0006091;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 HUMAN|HGNC=17655|UniProtKB=Q9H772 Q9H772 GREM2 PTHR15283:SF2 GREMLIN 1 GREMLIN-2 receptor regulator activity#GO:0030545;binding#GO:0005488;cytokine binding#GO:0019955;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;animal organ development#GO:0048513;negative regulation of cellular response to growth factor stimulus#GO:0090288;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;system development#GO:0048731;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=8030|UniProtKB=O00634 O00634 NTN3 PTHR10574:SF292 NETRIN/LAMININ-RELATED NETRIN-3 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;dendrite development#GO:0016358;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;tissue development#GO:0009888;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;motor neuron axon guidance#GO:0008045;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Axon guidance mediated by netrin#P00009>Netrin#P00357;Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344 HUMAN|HGNC=27559|UniProtKB=Q6P474 Q6P474 PDXDC2P PTHR42735:SF10 FAMILY NOT NAMED PYRIDOXAL-DEPENDENT DECARBOXYLASE DOMAIN-CONTAINING PROTEIN 1-RELATED lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell motility#GO:0048870;lipid catabolic process#GO:0016042;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;localization#GO:0051179;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;movement of cell or subcellular component#GO:0006928;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477;locomotion#GO:0040011;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=25241|UniProtKB=Q8N3R3 Q8N3R3 TCAIM PTHR31596:SF1 T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=222|UniProtKB=Q9UKP5 Q9UKP5 ADAMTS6 PTHR13723:SF27 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 6 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=10739|UniProtKB=Q9H3T3 Q9H3T3 SEMA6B PTHR11036:SF10 SEMAPHORIN SEMAPHORIN-6B receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=6560|UniProtKB=Q8NES3 Q8NES3 LFNG PTHR10811:SF7 FRINGE-RELATED BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE LUNATIC FRINGE transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of Notch signaling pathway#GO:0008593;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signaling#GO:0023052;Notch signaling pathway#GO:0007219 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Fringe#P01107 HUMAN|HGNC=16844|UniProtKB=Q02930 Q02930 CREB5 PTHR19304:SF8 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic leucine zipper transcription factor#PC00056 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 HUMAN|HGNC=3377|UniProtKB=P11171 P11171 EPB41 PTHR23280:SF12 4.1 G PROTEIN PROTEIN 4.1 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Nicotine pharmacodynamics pathway#P06587>EPB41#P06607;Dopamine receptor mediated signaling pathway#P05912>EPB41#P05966 HUMAN|HGNC=30041|UniProtKB=Q6P1J6 Q6P1J6 PLB1 PTHR21325:SF31 PHOSPHOLIPASE B, PLB1 PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED phospholipase#PC00186 HUMAN|HGNC=17298|UniProtKB=Q9HAW0 Q9HAW0 BRF2 PTHR11618:SF5 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION FACTOR IIIB 50 KDA SUBUNIT transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription factor binding#GO:0008134;RNA polymerase II general transcription initiation factor activity#GO:0016251;binding#GO:0005488;TBP-class protein binding#GO:0017025 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 HUMAN|HGNC=14369|UniProtKB=P21128 P21128 ENDOU PTHR12439:SF11 PLACENTAL PROTEIN 11-RELATED POLY(U)-SPECIFIC ENDORIBONUCLEASE HUMAN|HGNC=16762|UniProtKB=Q2M1K9 Q2M1K9 ZNF423 PTHR24388:SF52 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 423 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11943|UniProtKB=P63316 P63316 TNNC1 PTHR23064:SF47 TROPONIN TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES cation binding#GO:0043169;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;actin filament binding#GO:0051015;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;ion binding#GO:0043167;actin binding#GO:0003779 regulation of biological process#GO:0050789;regulation of multicellular organismal process#GO:0051239;regulation of muscle contraction#GO:0006937;skeletal muscle contraction#GO:0003009;system process#GO:0003008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of system process#GO:0044057;striated muscle contraction#GO:0006941;muscle system process#GO:0003012;muscle contraction#GO:0006936 supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;cytoskeleton#GO:0005856;myofibril#GO:0030016 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=30628|UniProtKB=Q96BD6 Q96BD6 SPSB1 PTHR12245:SF8 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 1 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=14280|UniProtKB=O76071 O76071 CIAO1 PTHR19920:SF0 WD40 PROTEIN CIAO1 CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=1778|UniProtKB=P50613 P50613 CDK7 PTHR24056:SF375 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 7 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;phosphorylation of RNA polymerase II C-terminal domain#GO:0070816;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=13497|UniProtKB=O75346 O75346 ZNF253 PTHR24384:SF181 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 253 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=32308|UniProtKB=Q5T7M4 Q5T7M4 C1QTNF12 PTHR24019:SF12 ADIPOLIN ADIPOLIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 positive regulation of signal transduction#GO:0009967;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;positive regulation of transmembrane transport#GO:0034764;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of transmembrane transport#GO:0034762;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;cellular metabolic process#GO:0044237;positive regulation of transport#GO:0051050;negative regulation of metabolic process#GO:0009892;response to organonitrogen compound#GO:0010243;cell communication#GO:0007154;carbohydrate transmembrane transport#GO:0034219;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;cellular carbohydrate metabolic process#GO:0044262;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;positive regulation of cell communication#GO:0010647;small molecule biosynthetic process#GO:0044283;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;monosaccharide metabolic process#GO:0005996;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;regulation of signaling#GO:0023051;transport#GO:0006810;biosynthetic process#GO:0009058;cellular response to nitrogen compound#GO:1901699;carbohydrate transport#GO:0008643;positive regulation of response to stimulus#GO:0048584;organic substance transport#GO:0071702;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;carbohydrate metabolic process#GO:0005975;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;carbohydrate biosynthetic process#GO:0016051;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;negative regulation of biosynthetic process#GO:0009890;transmembrane transport#GO:0055085;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;glucose metabolic process#GO:0006006;regulation of glucose metabolic process#GO:0010906;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;hexose metabolic process#GO:0019318 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 HUMAN|HGNC=2515|UniProtKB=O60716 O60716 CTNND1 PTHR10372:SF6 PLAKOPHILLIN-RELATED CATENIN DELTA-1 cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;anchoring junction#GO:0070161;intracellular#GO:0005622;cell-cell junction#GO:0005911;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 intermediate filament binding protein#PC00130 Cadherin signaling pathway#P00012>P120#P00473 HUMAN|HGNC=11087|UniProtKB=O75094 O75094 SLIT3 PTHR45836:SF9 SLIT HOMOLOG SLIT HOMOLOG 3 PROTEIN carbohydrate derivative binding#GO:0097367;binding#GO:0005488;heparin binding#GO:0008201;protein binding#GO:0005515;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 Axon guidance mediated by Slit/Robo#P00008>Slit#P00342 HUMAN|HGNC=1967|UniProtKB=P07510 P07510 CHRNG PTHR18945:SF60 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT GAMMA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>gamma#P01094;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 HUMAN|HGNC=9551|UniProtKB=P43686 P43686 PSMC4 PTHR23073:SF8 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6B positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription, initiation#GO:2000142;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of transcription initiation from RNA polymerase II promoter#GO:0060260;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;positive regulation of transcription initiation from RNA polymerase II promoter#GO:0060261;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of protein-containing complex assembly#GO:0043254;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of RNA polymerase II transcription preinitiation complex assembly#GO:0045899;positive regulation of cellular component biogenesis#GO:0044089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of protein-containing complex assembly#GO:0031334;regulation of primary metabolic process#GO:0080090;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of DNA-templated transcription, initiation#GO:2000144;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;intracellular#GO:0005622;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;proteasome regulatory particle, base subcomplex#GO:0008540 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Ubiquitin proteasome pathway#P00060>19S proteasome#P01494 HUMAN|HGNC=8363|UniProtKB=O14581 O14581 OR7A17 PTHR48001:SF173 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7A17 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=5108|UniProtKB=P31268 P31268 HOXA7 PTHR45659:SF12 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=15530|UniProtKB=Q9NRJ4 Q9NRJ4 TULP4 PTHR16517:SF2 TUBBY-RELATED TUBBY-RELATED PROTEIN 4 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;cellular protein localization#GO:0034613;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=1928|UniProtKB=O00409 O00409 FOXN3 PTHR13962:SF20 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD BOX PROTEIN N3 HUMAN|HGNC=21683|UniProtKB=Q6IQ20 Q6IQ20 NAPEPLD PTHR15032:SF4 N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 phospholipase#PC00186 HUMAN|HGNC=10008|UniProtKB=P18577 P18577 RHCE PTHR11730:SF43 AMMONIUM TRANSPORTER BLOOD GROUP RH(CE) POLYPEPTIDE-RELATED monovalent inorganic cation transmembrane transporter activity#GO:0015077;inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=25226|UniProtKB=Q5TYW1 Q5TYW1 ZNF658 PTHR24376:SF198 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 658-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=1334|UniProtKB=Q96IV6 Q96IV6 FAXDC2 PTHR11863:SF26 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;steroid metabolic process#GO:0008202;lipid metabolic process#GO:0006629;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 oxidase#PC00175 HUMAN|HGNC=20717|UniProtKB=Q6P597 Q6P597 KLC3 PTHR45783:SF1 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN 3 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 HUMAN|HGNC=7966|UniProtKB=Q13133 Q13133 NR1H3 PTHR24082:SF259 NUCLEAR HORMONE RECEPTOR OXYSTEROLS RECEPTOR LXR-ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of inflammatory response#GO:0050728;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;defense response#GO:0006952;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of defense response#GO:0031347;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;inflammatory response#GO:0006954;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;regulation of response to external stimulus#GO:0032101;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;regulation of response to stress#GO:0080134;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of inflammatory response#GO:0050727;response to external stimulus#GO:0009605;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=13371|UniProtKB=Q96JQ5 Q96JQ5 MS4A4A PTHR23320:SF144 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 4A transporter#PC00227 HUMAN|HGNC=24737|UniProtKB=Q5MCW4 Q5MCW4 ZNF569 PTHR24377:SF707 IP01015P-RELATED ZINC FINGER PROTEIN 569 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=436|UniProtKB=P20292 P20292 ALOX5AP PTHR10250:SF2 MICROSOMAL GLUTATHIONE S-TRANSFERASE ARACHIDONATE 5-LIPOXYGENASE-ACTIVATING PROTEIN lyase activity#GO:0016829;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;icosanoid metabolic process#GO:0006690;cellular metabolic process#GO:0044237;icosanoid biosynthetic process#GO:0046456;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;fatty acid derivative metabolic process#GO:1901568;carboxylic acid biosynthetic process#GO:0046394;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 transferase#PC00220 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Lipoxygenase#P00830 HUMAN|HGNC=804|UniProtKB=P05026 P05026 ATP1B1 PTHR11523:SF10 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;enzyme activator activity#GO:0008047;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;ATPase activator activity#GO:0001671;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;potassium ion transport#GO:0006813;cellular cation homeostasis#GO:0030003;cellular monovalent inorganic cation homeostasis#GO:0030004;metal ion transport#GO:0030001;monovalent inorganic cation transport#GO:0015672;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725;export from cell#GO:0140352 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=20393|UniProtKB=Q8N9L1 Q8N9L1 ZIC4 PTHR19818:SF91 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN ZIC 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;central nervous system development#GO:0007417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=19310|UniProtKB=Q86V86 Q86V86 PIM3 PTHR22984:SF26 SERINE/THREONINE-PROTEIN KINASE PIM SERINE/THREONINE-PROTEIN KINASE PIM-3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;negative regulation of programmed cell death#GO:0043069;apoptotic process#GO:0006915;protein autophosphorylation#GO:0046777;cell death#GO:0008219;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;negative regulation of apoptotic process#GO:0043066;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=18753|UniProtKB=Q8NI29 Q8NI29 FBXO27 PTHR12125:SF9 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX ONLY PROTEIN 27 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 HUMAN|HGNC=3057|UniProtKB=Q9Y4J8 Q9Y4J8 DTNA PTHR12268:SF19 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROBREVIN ALPHA synaptic signaling#GO:0099536;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell junction#GO:0030054;synapse#GO:0045202;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=28833|UniProtKB=Q9NTK5 Q9NTK5 OLA1 PTHR23305:SF11 OBG GTPASE FAMILY OBG-LIKE ATPASE 1 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 G-protein#PC00020 HUMAN|HGNC=28763|UniProtKB=Q96HS1 Q96HS1 PGAM5 PTHR20935:SF0 PHOSPHOGLYCERATE MUTASE-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL mutase#PC00160 HUMAN|HGNC=18537|UniProtKB=Q9NV92 Q9NV92 NDFIP2 PTHR13396:SF4 NEDD4 FAMILY INTERACTING PROTEIN 1/2 NEDD4 FAMILY-INTERACTING PROTEIN 2 protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;transport#GO:0006810;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;cation transport#GO:0006812;positive regulation of protein modification process#GO:0031401;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;metal ion transport#GO:0030001;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;ion transport#GO:0006811;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=35409|UniProtKB=A6NL88 A6NL88 SHISA7 PTHR31774:SF2 PROTEIN SHISA-9-RELATED PROTEIN SHISA-7 signal transduction#GO:0007165;regulation of neurotransmitter receptor activity#GO:0099601;transport#GO:0006810;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;ionotropic glutamate receptor signaling pathway#GO:0035235;cation transport#GO:0006812;cation transmembrane transport#GO:0098655;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;regulation of transmembrane transporter activity#GO:0022898;regulation of transporter activity#GO:0032409;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;transmembrane transport#GO:0055085;regulation of cation transmembrane transport#GO:1904062;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of AMPA receptor activity#GO:2000311;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;ion transmembrane transport#GO:0034220;regulation of synaptic plasticity#GO:0048167;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of signaling receptor activity#GO:0010469;response to stimulus#GO:0050896;regulation of ion transmembrane transport#GO:0034765;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of trans-synaptic signaling#GO:0099177 synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;leading edge membrane#GO:0031256;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;membrane protein complex#GO:0098796;postsynaptic specialization#GO:0099572;ion channel complex#GO:0034702;cell junction#GO:0030054;cell projection membrane#GO:0031253;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 HUMAN|HGNC=44152|UniProtKB=H3BV60 H3BV60 TGFBR3L PTHR14002:SF9 ENDOGLIN/TGF-BETA RECEPTOR TYPE III TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE 3-LIKE PROTEIN cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=18372|UniProtKB=Q9HD64 Q9HD64 XAGE1B PTHR14047:SF31 P ANTIGEN FAMILY MEMBER 5-RELATED X ANTIGEN FAMILY MEMBER 1 HUMAN|HGNC=6912|UniProtKB=P43243 P43243 MATR3 PTHR15592:SF2 MATRIN 3/NUCLEAR PROTEIN 220-RELATED MATRIN-3 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=5583|UniProtKB=A0A0C4DH30 A0A0C4DH30 IGHV3-16 PTHR23266:SF204 IMMUNOGLOBULIN HEAVY CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=22058|UniProtKB=Q8IV31 Q8IV31 TMEM139 PTHR36294:SF1 TRANSMEMBRANE PROTEIN 139 TRANSMEMBRANE PROTEIN 139 HUMAN|HGNC=19115|UniProtKB=P0DTE0 P0DTE0 TAS2R36 PTHR11394:SF139 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 19-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=6169|UniProtKB=Q14624 Q14624 ITIH4 PTHR10338:SF119 INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H4 protease inhibitor#PC00191 HUMAN|HGNC=13432|UniProtKB=Q9NV58 Q9NV58 RNF19A PTHR11685:SF111 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF19A ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;positive regulation of proteolysis#GO:0045862;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;positive regulation of proteolysis involved in cellular protein catabolic process#GO:1903052;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;regulation of cellular process#GO:0050794;positive regulation of catabolic process#GO:0009896;positive regulation of cellular protein catabolic process#GO:1903364;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;positive regulation of proteasomal protein catabolic process#GO:1901800;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;positive regulation of metabolic process#GO:0009893;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;regulation of cellular protein catabolic process#GO:1903362;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;regulation of proteolysis#GO:0030162;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis involved in cellular protein catabolic process#GO:1903050;organonitrogen compound metabolic process#GO:1901564;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of proteasomal protein catabolic process#GO:0061136;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=3473|UniProtKB=O95718 O95718 ESRRB PTHR48092:SF7 KNIRPS-RELATED PROTEIN-RELATED STEROID HORMONE RECEPTOR ERR2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=28987|UniProtKB=Q92615 Q92615 LARP4B PTHR22792:SF43 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 4B RNA metabolism protein#PC00031 HUMAN|HGNC=9711|UniProtKB=Q15269 Q15269 PWP2 PTHR19858:SF0 WD40 REPEAT PROTEIN PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 HUMAN|HGNC=3118|UniProtKB=Q16254 Q16254 E2F4 PTHR12081:SF42 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=17882|UniProtKB=Q8WXA9 Q8WXA9 SREK1 PTHR32343:SF71 SERINE/ARGININE-RICH SPLICING FACTOR SPLICING REGULATORY GLUTAMINE/LYSINE-RICH PROTEIN 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=15533|UniProtKB=Q9C004 Q9C004 SPRY4 PTHR12365:SF6 SPROUTY PROTEIN SPROUTY HOMOLOG 4 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;regulation of Ras protein signal transduction#GO:0046578;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;MAPK cascade#GO:0000165;protein modification process#GO:0036211;negative regulation of Ras protein signal transduction#GO:0046580;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;response to endogenous stimulus#GO:0009719;regulation of protein serine/threonine kinase activity#GO:0071900;negative regulation of small GTPase mediated signal transduction#GO:0051058;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;negative regulation of MAP kinase activity#GO:0043407;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;regulation of transferase activity#GO:0051338;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Spry#P00541;EGF receptor signaling pathway#P00018>SPRY#G01511;FGF signaling pathway#P00021>Spry#P00626 HUMAN|HGNC=29622|UniProtKB=Q8IVS2 Q8IVS2 MCAT PTHR42681:SF1 MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=26998|UniProtKB=Q6DD87 Q6DD87 ZNF787 PTHR24408:SF1 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 787 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29852|UniProtKB=O15049 O15049 N4BP3 PTHR32274:SF1 NEDD4-BINDING PROTEIN 3 NEDD4-BINDING PROTEIN 3 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 HUMAN|HGNC=26674|UniProtKB=A8TX70 A8TX70 COL6A5 PTHR22588:SF4 UNCHARACTERIZED COLLAGEN ALPHA-5(VI) CHAIN HUMAN|HGNC=24941|UniProtKB=P51991 P51991 HNRNPA3 PTHR48026:SF12 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A3 HUMAN|HGNC=8548|UniProtKB=P07237 P07237 P4HB PTHR18929:SF101 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to endoplasmic reticulum stress#GO:0034976;cellular process#GO:0009987;cellular response to stress#GO:0033554;protein folding#GO:0006457 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=15759|UniProtKB=Q16186 Q16186 ADRM1 PTHR12225:SF0 ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;proteasome binding#GO:0070628;ubiquitin binding#GO:0043130;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;proteasome complex#GO:0000502 HUMAN|HGNC=612|UniProtKB=P05090 P05090 APOD PTHR10612:SF34 APOLIPOPROTEIN D APOLIPOPROTEIN D lipid metabolic process#GO:0006629;response to stimulus#GO:0050896;response to stress#GO:0006950;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;response to oxidative stress#GO:0006979;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 apolipoprotein#PC00052 HUMAN|HGNC=2396|UniProtKB=P53673 P53673 CRYBA4 PTHR11818:SF19 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN A4 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=25123|UniProtKB=Q504Y2 Q504Y2 PKDCC PTHR46448:SF3 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN EXTRACELLULAR TYROSINE-PROTEIN KINASE PKDCC HUMAN|HGNC=18736|UniProtKB=Q6P9F5 Q6P9F5 TRIM40 PTHR24103:SF564 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE RNF187-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of NF-kappaB transcription factor activity#GO:0032088;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;innate immune response#GO:0045087;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;immune response#GO:0006955;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of molecular function#GO:0044092;negative regulation of DNA-binding transcription factor activity#GO:0043433 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=25418|UniProtKB=Q96C34 Q96C34 RUNDC1 PTHR22957:SF2 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN RUN DOMAIN-CONTAINING PROTEIN 1 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=17905|UniProtKB=Q9Y613 Q9Y613 FHOD1 PTHR45920:SF2 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FH1/FH2 DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cortical cytoskeleton organization#GO:0030865;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|Gene=YC006_HUMAN|UniProtKB=Q6ZUG5 Q6ZUG5 - PTHR33667:SF7 SI:DKEY-57N24.6 DUF4550 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=28136|UniProtKB=Q5XUX1 Q5XUX1 FBXW9 PTHR19855:SF19 WD40 REPEAT PROTEIN 12, 37 F-BOX/WD REPEAT-CONTAINING PROTEIN 9 HUMAN|HGNC=50322|UniProtKB=P0DP04 P0DP04 IGHV3-43D PTHR23266:SF236 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-43-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=16381|UniProtKB=Q5SGD2 Q5SGD2 PPM1L PTHR13832:SF571 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1L hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=19194|UniProtKB=Q96RW7 Q96RW7 HMCN1 PTHR23277:SF107 NECTIN-RELATED HEMICENTIN-1 cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;biological adhesion#GO:0022610 cell junction#GO:0030054;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 HUMAN|HGNC=21480|UniProtKB=Q9BVJ7 Q9BVJ7 DUSP23 PTHR23339:SF26 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 protein phosphatase#PC00195 HUMAN|HGNC=19942|UniProtKB=O43617 O43617 TRAPPC3 PTHR13048:SF2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;intra-Golgi vesicle-mediated transport#GO:0006891;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=11175|UniProtKB=O95219 O95219 SNX4 PTHR46596:SF1 SORTING NEXIN-4 SORTING NEXIN-4 scaffold/adaptor protein#PC00226 HUMAN|HGNC=2877|UniProtKB=O60879 O60879 DIAPH2 PTHR45691:SF3 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 2 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 HUMAN|HGNC=9816|UniProtKB=Q92878 Q92878 RAD50 PTHR18867:SF12 RAD50 DNA REPAIR PROTEIN RAD50 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;endonuclease activity#GO:0004519;transferase activity, transferring phosphorus-containing groups#GO:0016772;double-stranded DNA binding#GO:0003690;deoxyribonuclease activity#GO:0004536;pyrophosphatase activity#GO:0016462;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;nucleobase-containing compound kinase activity#GO:0019205;ATPase activity#GO:0016887;nuclease activity#GO:0004518;helicase activity#GO:0004386;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776;DNA-dependent ATPase activity#GO:0008094;adenylate kinase activity#GO:0004017;exonuclease activity#GO:0004527;kinase activity#GO:0016301;sequence-specific DNA binding#GO:0043565;hydrolase activity#GO:0016787;endodeoxyribonuclease activity#GO:0004520;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;3'-5' exonuclease activity#GO:0008408 telomere maintenance via telomere lengthening#GO:0010833;cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;telomere-telomerase complex assembly#GO:1905324;DNA geometric change#GO:0032392;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;reproductive process#GO:0022414;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;telomere capping#GO:0016233;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;RNA-dependent DNA biosynthetic process#GO:0006278;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;aromatic compound biosynthetic process#GO:0019438;cellular aromatic compound metabolic process#GO:0006725;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;telomere maintenance#GO:0000723;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic recombination#GO:0006312;DNA duplex unwinding#GO:0032508;telomere maintenance via telomerase#GO:0007004;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;biological regulation#GO:0065007;organelle fission#GO:0048285;cell cycle#GO:0007049;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=29799|UniProtKB=Q86VZ5 Q86VZ5 SGMS1 PTHR21290:SF28 SPHINGOMYELIN SYNTHETASE PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;phosphate-containing compound metabolic process#GO:0006796;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;integral component of plasma membrane#GO:0005887;membrane-bounded organelle#GO:0043227;intrinsic component of plasma membrane#GO:0031226;Golgi membrane#GO:0000139;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=8013|UniProtKB=P82970 P82970 HMGN5 PTHR23145:SF6 NUCLEOSOMAL BINDING PROTEIN 1 HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 5 HUMAN|HGNC=32220|UniProtKB=Q6IPT4 Q6IPT4 CYB5RL PTHR19370:SF184 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE-LIKE reductase#PC00198 HUMAN|HGNC=18043|UniProtKB=Q7L590 Q7L590 MCM10 PTHR13454:SF11 PROTEIN MCM10 HOMOLOG PROTEIN MCM10 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;DNA biosynthetic process#GO:0071897;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;pre-replicative complex#GO:0036387;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;MCM complex#GO:0042555;CMG complex#GO:0071162;cellular anatomical entity#GO:0110165;organelle#GO:0043226;replication fork protection complex#GO:0031298;intracellular organelle#GO:0043229;nuclear pre-replicative complex#GO:0005656;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;GINS complex#GO:0000811;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nuclear replication fork#GO:0043596;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;replication fork#GO:0005657 HUMAN|HGNC=30014|UniProtKB=Q96LB9 Q96LB9 PGLYRP3 PTHR11022:SF12 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN RECOGNITION PROTEIN 3 HUMAN|HGNC=3616|UniProtKB=P12318 P12318 FCGR2A PTHR11481:SF97 IMMUNOGLOBULIN FC RECEPTOR LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR II-A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=7518|UniProtKB=Q8TAX7 Q8TAX7 MUC7 PTHR41683:SF1 MUCIN-7 MUCIN-7 membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 HUMAN|HGNC=23456|UniProtKB=P0C7U1 P0C7U1 ASAH2B PTHR12670:SF1 CERAMIDASE NEUTRAL CERAMIDASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;alcohol biosynthetic process#GO:0046165;organonitrogen compound catabolic process#GO:1901565;organic hydroxy compound biosynthetic process#GO:1901617;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;carboxylic acid biosynthetic process#GO:0046394;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid catabolic process#GO:0044242;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;long-chain fatty acid metabolic process#GO:0001676;organic hydroxy compound metabolic process#GO:1901615;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;monocarboxylic acid metabolic process#GO:0032787;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=22265|UniProtKB=Q7RTS1 Q7RTS1 BHLHA15 PTHR19290:SF160 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 15 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=4651|UniProtKB=P29084 P29084 GTF2E2 PTHR12716:SF8 TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 General transcription regulation#P00023>TFIIE#P00666;Transcription regulation by bZIP transcription factor#P00055>TFIIEbeta#P01386;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395;General transcription regulation#P00023>TFIIEbeta#P00659 HUMAN|HGNC=25192|UniProtKB=Q96BM9 Q96BM9 ARL8A PTHR45732:SF4 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8A bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=4682|UniProtKB=Q02747 Q02747 GUCA2A PTHR11318:SF3 GUANYLIN FAMILY MEMBER GUANYLIN lyase activity#GO:0016829;molecular function regulator#GO:0098772;cyclase activity#GO:0009975;enzyme activator activity#GO:0008047;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095 HUMAN|HGNC=26669|UniProtKB=Q8NA47 Q8NA47 CCDC63 PTHR21694:SF18 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 63 HUMAN|HGNC=17946|UniProtKB=Q9Y314 Q9Y314 NOSIP PTHR13063:SF10 ENOS INTERACTING PROTEIN NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=4724|UniProtKB=P04908 P04908 H2AC8 PTHR23430:SF196 HISTONE H2A HISTONE H2A TYPE 1-B/E heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=13629|UniProtKB=Q96DU9 Q96DU9 PABPC5 PTHR24012:SF682 RNA BINDING PROTEIN POLYADENYLATE-BINDING PROTEIN 5 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=18599|UniProtKB=Q9BSJ2 Q9BSJ2 TUBGCP2 PTHR19302:SF13 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component biogenesis#GO:0044085;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;microtubule polymerization or depolymerization#GO:0031109;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;microtubule polymerization#GO:0046785;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;reproductive process#GO:0022414;spindle assembly#GO:0051225;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cytoplasmic microtubule organization#GO:0031122;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;meiotic cell cycle#GO:0051321;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;microtubule-based process#GO:0007017;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;protein polymerization#GO:0051258;organelle fission#GO:0048285;cell cycle#GO:0007049 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;intracellular#GO:0005622;gamma-tubulin complex#GO:0000930;microtubule cytoskeleton#GO:0015630;cell division site#GO:0032153;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=29196|UniProtKB=Q5BKX6 Q5BKX6 SLC45A4 PTHR19432:SF7 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 4 solute:proton symporter activity#GO:0015295;inorganic molecular entity transmembrane transporter activity#GO:0015318;secondary active transmembrane transporter activity#GO:0015291;solute:cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;active transmembrane transporter activity#GO:0022804;active ion transmembrane transporter activity#GO:0022853 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=19285|UniProtKB=Q8IZE3 Q8IZE3 SCYL3 PTHR12984:SF15 SCY1-RELATED S/T PROTEIN KINASE-LIKE PROTEIN-ASSOCIATING WITH THE CARBOXYL-TERMINAL DOMAIN OF EZRIN non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=2961|UniProtKB=Q14204 Q14204 DYNC1H1 PTHR10676:SF314 DYNEIN HEAVY CHAIN FAMILY PROTEIN CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 vesicle transport along microtubule#GO:0047496;nuclear migration#GO:0007097;cellular localization#GO:0051641;organelle localization#GO:0051640;nuclear division#GO:0000280;transport#GO:0006810;cell cycle process#GO:0022402;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;supramolecular fiber organization#GO:0097435;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;establishment of organelle localization#GO:0051656;spindle localization#GO:0051653;cytoplasmic microtubule organization#GO:0031122;vesicle localization#GO:0051648;cellular component organization#GO:0016043;cellular process#GO:0009987;transport along microtubule#GO:0010970;establishment of spindle localization#GO:0051293;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;movement of cell or subcellular component#GO:0006928;cell cycle#GO:0007049;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;nucleus localization#GO:0051647;vesicle cytoskeletal trafficking#GO:0099518 supramolecular complex#GO:0099080;catalytic complex#GO:1902494;cytoplasmic microtubule#GO:0005881;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;cell cortex#GO:0005938;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;cytoskeleton#GO:0005856;cytoplasmic dynein complex#GO:0005868;microtubule#GO:0005874 microtubule binding motor protein#PC00156 Huntington disease#P00029>Dynein complex#P00774 HUMAN|HGNC=45147|UniProtKB=F8VTS6 F8VTS6 RFPL4AL1 PTHR25462:SF245 BONUS, ISOFORM C-RELATED RET FINGER PROTEIN-LIKE 4A-RELATED HUMAN|HGNC=11050|UniProtKB=P31645 P31645 SLC6A4 PTHR11616:SF105 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT SEROTONIN TRANSPORTER inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;sodium:chloride symporter activity#GO:0015378;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;cation binding#GO:0043169;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;organic cyclic compound binding#GO:0097159;metal ion transmembrane transporter activity#GO:0046873;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;monoamine transmembrane transporter activity#GO:0008504;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 organic hydroxy compound transport#GO:0015850;cellular localization#GO:0051641;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of neurotransmitter levels#GO:0001505;organic cation transport#GO:0015695;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;sodium ion transmembrane transport#GO:0035725 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 primary active transporter#PC00068 5HT3 type receptor mediated signaling pathway#P04375>5HT transporter#P04421;5HT2 type receptor mediated signaling pathway#P04374>5HT transporter#P04417;5HT4 type receptor mediated signaling pathway#P04376>5HT transporter#P04431;5HT1 type receptor mediated signaling pathway#P04373>5HT transporter#P04409 HUMAN|HGNC=8546|UniProtKB=P13674 P13674 P4HA1 PTHR10869:SF101 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213 macromolecule modification#GO:0043412;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 protein modifying enzyme#PC00260 HUMAN|HGNC=4691|UniProtKB=P51841 P51841 GUCY2F PTHR11920:SF349 GUANYLYL CYCLASE RETINAL GUANYLYL CYCLASE 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;organophosphate biosynthetic process#GO:0090407;cyclic nucleotide metabolic process#GO:0009187;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nucleotide biosynthetic process#GO:0009165;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;signaling#GO:0023052;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;response to stimulus#GO:0050896;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 guanylate cyclase#PC00114 HUMAN|HGNC=26321|UniProtKB=Q53RT3 Q53RT3 ASPRV1 PTHR37006:SF1 RETROVIRAL-LIKE ASPARTIC PROTEASE 1 RETROVIRAL-LIKE ASPARTIC PROTEASE 1 viral or transposable element protein#PC00237 HUMAN|HGNC=10421|UniProtKB=P61247 P61247 RPS3A PTHR11830:SF28 40S RIBOSOMAL PROTEIN S3A 40S RIBOSOMAL PROTEIN S3A cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ribosomal protein#PC00202 HUMAN|HGNC=6448|UniProtKB=Q15323 Q15323 KRT31 PTHR23239:SF97 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA1 HUMAN|HGNC=6663|UniProtKB=P23490 P23490 LORICRIN PTHR39228:SF1 LORICRIN LORICRIN HUMAN|HGNC=25475|UniProtKB=Q9NWD9 Q9NWD9 BEX4 PTHR13987:SF3 PROTEIN BEX4 PROTEIN BEX4 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=10877|UniProtKB=Q9NYZ4 Q9NYZ4 SIGLEC8 PTHR12035:SF106 SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN SIALIC ACID-BINDING IG-LIKE LECTIN 8 carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;organic acid binding#GO:0043177;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125 HUMAN|HGNC=4778|UniProtKB=Q16695 Q16695 H3-4 PTHR11426:SF240 HISTONE H3 HISTONE H3.1T histone#PC00118 DNA replication#P00017>Histones#P00527 HUMAN|HGNC=4193|UniProtKB=P30793 P30793 GCH1 PTHR11109:SF11 GTP CYCLOHYDROLASE I GTP CYCLOHYDROLASE 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;pteridine-containing compound metabolic process#GO:0042558;alcohol biosynthetic process#GO:0046165;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic hydroxy compound biosynthetic process#GO:1901617;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 Tetrahydrofolate biosynthesis#P02742>GTP cyclohydrolase#P02951 HUMAN|HGNC=10535|UniProtKB=Q9Y6B6 Q9Y6B6 SAR1B PTHR45684:SF20 RE74312P GTP-BINDING PROTEIN SAR1B pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 vesicle targeting, to, from or within Golgi#GO:0048199;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;Golgi vesicle budding#GO:0048194;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;establishment of vesicle localization#GO:0051650;vesicle organization#GO:0016050;regulation of protein transport#GO:0051223;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of protein localization#GO:0032880;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;vesicle localization#GO:0051648;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;regulation of cellular localization#GO:0060341;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;COPII-coated vesicle budding#GO:0090114;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=7883|UniProtKB=Q9UM47 Q9UM47 NOTCH3 PTHR45836:SF17 SLIT HOMOLOG NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 3 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330;Notch signaling pathway#GO:0007219 receptor complex#GO:0043235;cell surface#GO:0009986;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Notch signaling pathway#P00045>Notch#P01099;Notch signaling pathway#P00045>NIct#P01119;Alzheimer disease-presenilin pathway#P00004>Notch N-terminal fragment#P00171;Notch signaling pathway#P00045>NIcs#P01120;Notch signaling pathway#P00045>Ntm#P01114;Alzheimer disease-presenilin pathway#P00004>Notch C-terminal fragment#P00120;Notch signaling pathway#P00045>Next#P01103;Alzheimer disease-presenilin pathway#P00004>NICD#P00122;Alzheimer disease-presenilin pathway#P00004>Notch#P00176;Alzheimer disease-presenilin pathway#P00004>Notch fragment#P00154;Alzheimer disease-presenilin pathway#P00004>Notch transmembrane fragment#P00135;Alzheimer disease-presenilin pathway#P00004>Notch extracellular fragment#P00179 HUMAN|HGNC=17091|UniProtKB=Q92542 Q92542 NCSTN PTHR21092:SF0 NICASTRIN NICASTRIN macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;protein metabolic process#GO:0019538;protein processing#GO:0016485;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Notch signaling pathway#P00045>Nicastrin#P01108;Alzheimer disease-presenilin pathway#P00004>Nicastrin#P00115;Alzheimer disease-amyloid secretase pathway#P00003>Nicastrin#P00095 HUMAN|HGNC=21011|UniProtKB=Q8IVL8 Q8IVL8 CPO PTHR11705:SF19 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE O hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=25247|UniProtKB=Q8IYW2 Q8IYW2 CFAP46 PTHR15977:SF15 FAMILY NOT NAMED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 46 HUMAN|HGNC=746|UniProtKB=P04424 P04424 ASL PTHR43814:SF1 ARGININOSUCCINATE LYASE ARGININOSUCCINATE LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 lyase#PC00144 Arginine biosynthesis#P02728>argininosuccinate lyase#P02841 HUMAN|HGNC=21181|UniProtKB=Q6EEV6 Q6EEV6 SUMO4 PTHR10562:SF79 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 3-RELATED enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 p53 pathway#P00059>Sumo-1 ligase#P04635 HUMAN|HGNC=25846|UniProtKB=Q53H96 Q53H96 PYCR3 PTHR11645:SF22 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE 3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 reductase#PC00198 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 HUMAN|HGNC=9460|UniProtKB=P22891 P22891 PROZ PTHR24278:SF20 COAGULATION FACTOR VITAMIN K-DEPENDENT PROTEIN Z extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 Blood coagulation#P00011>PZ#P00407 HUMAN|HGNC=29587|UniProtKB=Q8TAC1 Q8TAC1 RFESD PTHR21496:SF0 FERREDOXIN-RELATED RIESKE DOMAIN-CONTAINING PROTEIN oxidoreductase#PC00176 HUMAN|HGNC=30216|UniProtKB=O43633 O43633 CHMP2A PTHR10476:SF4 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2A endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;peptide transport#GO:0015833;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=19600|UniProtKB=Q9H340 Q9H340 OR51B6 PTHR26450:SF22 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51B6 transmembrane signal receptor#PC00197 HUMAN|HGNC=30036|UniProtKB=Q9HAU0 Q9HAU0 PLEKHA5 PTHR12752:SF3 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 5 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2212|UniProtKB=P12110 P12110 COL6A2 PTHR24020:SF29 COLLAGEN ALPHA COLLAGEN ALPHA-2(VI) CHAIN extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>EMC#P00863;Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=10304|UniProtKB=P40429 P40429 RPL13A PTHR11545:SF30 RIBOSOMAL PROTEIN L13 60S RIBOSOMAL PROTEIN L13A structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;negative regulation of translation#GO:0017148;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=1621|UniProtKB=Q92526 Q92526 CCT6B PTHR11353:SF58 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ZETA-2 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;chaperone complex#GO:0101031;cellular anatomical entity#GO:0110165;chaperonin-containing T-complex#GO:0005832;intracellular#GO:0005622 chaperonin#PC00073 HUMAN|HGNC=30622|UniProtKB=Q08AE8 Q08AE8 SPIRE1 PTHR21345:SF8 SPIRE PROTEIN SPIRE HOMOLOG 1 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;positive regulation of supramolecular fiber organization#GO:1902905;membrane organization#GO:0061024;nuclear division#GO:0000280;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;cytokinetic process#GO:0032506;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;cytoskeleton-dependent cytokinesis#GO:0061640;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010;multi-organism reproductive process#GO:0044703;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;multicellular organismal reproductive process#GO:0048609;protein-containing complex subunit organization#GO:0043933;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;gamete generation#GO:0007276;meiotic cell cycle#GO:0051321;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;regulation of cellular process#GO:0050794;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;cell division#GO:0051301;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;cellular process involved in reproduction in multicellular organism#GO:0022412;transport#GO:0006810;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;actin filament polymerization#GO:0030041;regulation of protein-containing complex assembly#GO:0043254;meiotic cell cycle process#GO:1903046;supramolecular fiber organization#GO:0097435;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;cytokinesis#GO:0000910;spindle localization#GO:0051653;regulation of anatomical structure size#GO:0090066;membrane fission#GO:0090148;multicellular organism reproduction#GO:0032504;regulation of actin filament length#GO:0030832;actin filament bundle assembly#GO:0051017;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;multi-organism process#GO:0051704;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;establishment of spindle localization#GO:0051293;positive regulation of protein-containing complex assembly#GO:0031334;regulation of cellular component size#GO:0032535;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;microtubule-based process#GO:0007017;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;cell cortex#GO:0005938;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=9339|UniProtKB=Q04118 Q04118 PRB3 PTHR23203:SF4 PROLINE-RICH PROTEIN BASIC SALIVARY PROLINE-RICH PROTEIN 3 antimicrobial response protein#PC00051 HUMAN|HGNC=14892|UniProtKB=Q9UHL4 Q9UHL4 DPP7 PTHR11010:SF107 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED DIPEPTIDYL PEPTIDASE 2 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 serine protease#PC00203 HUMAN|HGNC=19998|UniProtKB=O14787 O14787 TNPO2 PTHR10527:SF17 IMPORTIN BETA TRANSPORTIN-2 signal sequence binding#GO:0005048;transporter activity#GO:0005215;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=21882|UniProtKB=A0AVF1 A0AVF1 TTC26 PTHR14781:SF0 UNCHARACTERIZED INTRAFLAGELLAR TRANSPORT PROTEIN 56 protein-containing complex binding#GO:0044877;binding#GO:0005488 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;ciliary base#GO:0097546;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;intracellular non-membrane-bounded organelle#GO:0043232;ciliary transition fiber#GO:0097539;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=11320|UniProtKB=Q8IZP0 Q8IZP0 ABI1 PTHR10460:SF2 ABL INTERACTOR FAMILY MEMBER ABL INTERACTOR 1 protein binding#GO:0005515;binding#GO:0005488 cell leading edge#GO:0031252;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=24616|UniProtKB=Q8N1G1 Q8N1G1 REXO1 PTHR12801:SF62 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 1 HOMOLOG hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 exoribonuclease#PC00099 HUMAN|HGNC=14704|UniProtKB=Q8NGS6 Q8NGS6 OR13C3 PTHR26453:SF34 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C3 transmembrane signal receptor#PC00197 HUMAN|HGNC=14215|UniProtKB=Q9BYV6 Q9BYV6 TRIM55 PTHR24103:SF640 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 55 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=21052|UniProtKB=Q7Z5Y7 Q7Z5Y7 KCTD20 PTHR21637:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD20 positive regulation of phosphorylation#GO:0042327;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of cellular process#GO:0048522;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of metabolic process#GO:0009893;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=25145|UniProtKB=Q96G42 Q96G42 KLHDC7B PTHR45972:SF5 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 7B HUMAN|HGNC=2990|UniProtKB=Q99704 Q99704 DOK1 PTHR21258:SF46 DOCKING PROTEIN RELATED DOCKING PROTEIN 1 Angiogenesis#P00005>Dok-R#P00180 HUMAN|HGNC=10046|UniProtKB=P12724 P12724 RNASE3 PTHR11437:SF3 RIBONUCLEASE EOSINOPHIL CATIONIC PROTEIN ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to other organism#GO:0098542;response to chemical#GO:0042221;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952;locomotion#GO:0040011;chemotaxis#GO:0006935;taxis#GO:0042330 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=24557|UniProtKB=Q9H8H0 Q9H8H0 NOL11 PTHR15633:SF3 UNCHARACTERIZED NUCLEOLAR PROTEIN 11 HUMAN|HGNC=11442|UniProtKB=O15400 O15400 STX7 PTHR19957:SF90 SYNTAXIN SYNTAXIN-7 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;SNARE complex#GO:0031201;cell junction#GO:0030054;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 HUMAN|HGNC=16173|UniProtKB=Q9P104 Q9P104 DOK5 PTHR21258:SF45 DOCKING PROTEIN RELATED DOCKING PROTEIN 5 HUMAN|HGNC=29090|UniProtKB=A6NHR9 A6NHR9 SMCHD1 PTHR22640:SF2 UNCHARACTERIZED STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=21156|UniProtKB=Q9BYE7 Q9BYE7 PCGF6 PTHR45893:SF2 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 6 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone ubiquitination#GO:0016574;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;histone H2A ubiquitination#GO:0033522;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;PRC1 complex#GO:0035102;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 HUMAN|HGNC=24096|UniProtKB=Q8IVW1 Q8IVW1 ARL17A PTHR11711:SF347 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 17-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 G-protein#PC00020 HUMAN|HGNC=6984|UniProtKB=P23368 P23368 ME2 PTHR23406:SF27 MALIC ENZYME-RELATED NAD-DEPENDENT MALIC ENZYME, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176 HUMAN|HGNC=22195|UniProtKB=Q76N89 Q76N89 HECW1 PTHR11254:SF79 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE HECW1 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=30293|UniProtKB=Q8WZ71 Q8WZ71 TMEM158 PTHR38324:SF1 TRANSMEMBRANE PROTEIN 158 TRANSMEMBRANE PROTEIN 158 HUMAN|HGNC=11620|UniProtKB=Q14241 Q14241 ELOA PTHR15141:SF75 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN-A HUMAN|HGNC=25085|UniProtKB=Q5XKR9 Q5XKR9 FAM104B PTHR34763:SF2 PROTEIN FAM104A PROTEIN FAM104B HUMAN|HGNC=28949|UniProtKB=Q15051 Q15051 IQCB1 PTHR15673:SF2 IQ CALMODULIN-BINDING MOTIF CONTAINING PROTEIN 1 IQ CALMODULIN-BINDING MOTIF-CONTAINING PROTEIN 1 HUMAN|HGNC=14985|UniProtKB=Q86V48 Q86V48 LUZP1 PTHR23166:SF7 FILAMIN/GPBP-INTERACTING PROTEIN LEUCINE ZIPPER PROTEIN 1 HUMAN|HGNC=18639|UniProtKB=O95208 O95208 EPN2 PTHR12276:SF50 EPSIN/ENT-RELATED EPSIN-2 protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;membrane coat#GO:0030117;coated vesicle membrane#GO:0030662;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886 HUMAN|HGNC=19592|UniProtKB=Q8NG77 Q8NG77 OR2T12 PTHR26453:SF643 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T12 transmembrane signal receptor#PC00197 HUMAN|HGNC=13823|UniProtKB=Q8TDF5 Q8TDF5 NETO1 PTHR24251:SF27 OVOCHYMASE-RELATED NEUROPILIN AND TOLLOID-LIKE PROTEIN 1 serine protease#PC00203 HUMAN|HGNC=4053|UniProtKB=P05161 P05161 ISG15 PTHR10666:SF267 UBIQUITIN UBIQUITIN-LIKE PROTEIN ISG15 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17257|UniProtKB=O95238 O95238 SPDEF PTHR11849:SF182 ETS SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=18515|UniProtKB=Q9BQJ4 Q9BQJ4 TMEM47 PTHR14399:SF3 P53-INDUCED PROTEIN RELATED TRANSMEMBRANE PROTEIN 47 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 HUMAN|HGNC=26567|UniProtKB=Q96LZ7 Q96LZ7 RMDN2 PTHR16056:SF15 UNCHARACTERIZED REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 2 HUMAN|HGNC=28881|UniProtKB=Q8NI35 Q8NI35 PATJ PTHR19964:SF11 MULTIPLE PDZ DOMAIN PROTEIN INAD-LIKE PROTEIN HUMAN|HGNC=30233|UniProtKB=Q5T9Z0 Q5T9Z0 TEDDM1 PTHR46441:SF2 TRANSMEMBRANE EPIDIDYMAL FAMILY MEMBER 3 TRANSMEMBRANE EPIDIDYMAL PROTEIN 1 HUMAN|HGNC=15850|UniProtKB=Q96T49 Q96T49 PPP1R16B PTHR24186:SF6 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 16B hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;protein phosphatase 1 binding#GO:0008157;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;regulation of nitrogen compound metabolic process#GO:0051171;epithelium development#GO:0060429;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;regulation of angiogenesis#GO:0045765;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of vasculature development#GO:1901342;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;sprouting angiogenesis#GO:0002040;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;tube development#GO:0035295;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;angiogenesis#GO:0001525;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;dephosphorylation#GO:0016311;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase modulator#PC00184 HUMAN|HGNC=24005|UniProtKB=A5X5Y0 A5X5Y0 HTR3E PTHR18945:SF811 NEUROTRANSMITTER GATED ION CHANNEL 5-HYDROXYTRYPTAMINE RECEPTOR 3E signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;binding#GO:0005488 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;system process#GO:0003008;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052 synapse#GO:0045202;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=6304|UniProtKB=P24390 P24390 KDELR1 PTHR10585:SF61 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR 1 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=5417|UniProtKB=P01562 P01562 IFNA1 PTHR11691:SF64 TYPE I INTERFERON INTERFERON ALPHA-1/13 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=11531|UniProtKB=O75478 O75478 TADA2A PTHR12374:SF20 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-ALPHA transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;binding#GO:0005488 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;positive regulation of protein modification process#GO:0031401;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of chromatin organization#GO:1902275;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of histone modification#GO:0031056;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of cellular protein metabolic process#GO:0032270;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=33984|UniProtKB=A6NK89 A6NK89 RASSF10 PTHR15286:SF13 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 10 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3540|UniProtKB=Q96RI0 Q96RI0 F2RL3 PTHR24232:SF22 G-PROTEIN COUPLED RECEPTOR PROTEINASE-ACTIVATED RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Blood coagulation#P00011>PAR-4#P00461 HUMAN|HGNC=19042|UniProtKB=Q96GX5 Q96GX5 MASTL PTHR24356:SF1 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE GREATWALL transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=28477|UniProtKB=Q8NBM8 Q8NBM8 PCYOX1L PTHR15944:SF2 FARNESYLCYSTEINE LYASE PRENYLCYSTEINE OXIDASE-LIKE oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 lyase#PC00144 HUMAN|Gene=YG039_HUMAN|UniProtKB=Q8N976 Q8N976 - PTHR12138:SF124 PRIMATE-EXPANDED PROTEIN FAMILY SUBFAMILY NOT NAMED HUMAN|HGNC=7567|UniProtKB=P12882 P12882 MYH1 PTHR45615:SF2 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-1 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=11584|UniProtKB=Q9UHD2 Q9UHD2 TBK1 PTHR22969:SF14 IKB KINASE SERINE/THREONINE-PROTEIN KINASE TBK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Toll receptor signaling pathway#P00054>TBK1#P01361 HUMAN|HGNC=4474|UniProtKB=P46092 P46092 CCR10 PTHR10489:SF735 CELL ADHESION MOLECULE C-C CHEMOKINE RECEPTOR TYPE 10 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=3650|UniProtKB=P39748 P39748 FEN1 PTHR11081:SF58 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE 1 hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;magnesium ion binding#GO:0000287;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;transition metal ion binding#GO:0046914;endonuclease activity#GO:0004519;metal ion binding#GO:0046872;exonuclease activity#GO:0004527;deoxyribonuclease activity#GO:0004536;catalytic activity, acting on RNA#GO:0140098;cation binding#GO:0043169;ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;endodeoxyribonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;ion binding#GO:0043167 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 exodeoxyribonuclease#PC00098 HUMAN|HGNC=14096|UniProtKB=O75467 O75467 ZNF324 PTHR24377:SF621 IP01015P-RELATED ZINC FINGER PROTEIN 324A cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=14795|UniProtKB=Q8NGJ6 Q8NGJ6 OR51A4 PTHR26450:SF168 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51A2-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=11173|UniProtKB=O60749 O60749 SNX2 PTHR10555:SF31 SORTING NEXIN SORTING NEXIN-2 lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18861|UniProtKB=Q6PIU1 Q6PIU1 KCNV1 PTHR11537:SF38 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY V MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=17098|UniProtKB=Q9UPY3 Q9UPY3 DICER1 PTHR14950:SF37 DICER-RELATED ENDORIBONUCLEASE DICER HUMAN|HGNC=14731|UniProtKB=Q96R72 Q96R72 OR4K3 PTHR48002:SF24 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4K3 transmembrane signal receptor#PC00197 HUMAN|HGNC=28908|UniProtKB=Q9UKB3 Q9UKB3 DNAJC12 PTHR44500:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 chaperone#PC00072 HUMAN|HGNC=19157|UniProtKB=Q8NEV9 Q8NEV9 IL27 PTHR20879:SF1 INTERLEUKIN-27 SUBUNIT ALPHA INTERLEUKIN-27 SUBUNIT ALPHA interleukin superfamily#PC00128 HUMAN|HGNC=26556|UniProtKB=Q8N4P6 Q8N4P6 LRRC71 PTHR46984:SF1 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 71 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 71 HUMAN|HGNC=18297|UniProtKB=Q9UKJ0 Q9UKJ0 PILRB PTHR15549:SF7 PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR BETA protein binding#GO:0005515;MHC protein binding#GO:0042287;binding#GO:0005488;signaling receptor binding#GO:0005102 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=6449|UniProtKB=Q14532 Q14532 KRT32 PTHR23239:SF155 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA2 HUMAN|HGNC=10939|UniProtKB=P43005 P43005 SLC1A1 PTHR11958:SF97 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER 3 primary active transporter#PC00068 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 HUMAN|HGNC=5418|UniProtKB=P01566 P01566 IFNA10 PTHR11691:SF66 TYPE I INTERFERON INTERFERON ALPHA-10-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=37205|UniProtKB=A6NE82 A6NE82 MBD3L3 PTHR12396:SF6 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG-BINDING DOMAIN PROTEIN 3-LIKE 2-RELATED HUMAN|HGNC=8858|UniProtKB=P56589 P56589 PEX3 PTHR28080:SF1 PEROXISOMAL BIOGENESIS FACTOR 3 PEROXISOMAL BIOGENESIS FACTOR 3 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein targeting to peroxisome#GO:0006625;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein localization to peroxisome#GO:0072662;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein targeting to membrane#GO:0006612;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;microbody membrane#GO:0031903;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;integral component of peroxisomal membrane#GO:0005779;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777 HUMAN|HGNC=16949|UniProtKB=Q9NX05 Q9NX05 FAM120C PTHR15976:SF15 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PPAR-GAMMA-LIKE PROTEIN 2 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=8634|UniProtKB=P40426 P40426 PBX3 PTHR11850:SF97 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;sensory system development#GO:0048880;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;neuron development#GO:0048666;multicellular organismal process#GO:0032501;sensory organ development#GO:0007423;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;visual system development#GO:0150063;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;eye development#GO:0001654;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|Gene=ENH1_HUMAN|UniProtKB=Q9N2K0 Q9N2K0 - PTHR10424:SF60 VIRAL ENVELOPE PROTEIN HERV-H_2Q24.1 PROVIRUS ANCESTRAL ENV POLYPROTEIN-RELATED viral or transposable element protein#PC00237 HUMAN|HGNC=6120|UniProtKB=Q13568 Q13568 IRF5 PTHR11949:SF10 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=16171|UniProtKB=Q9H444 Q9H444 CHMP4B PTHR22761:SF4 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 4B endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;vacuolar transport#GO:0007034;transport#GO:0006810;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;cellular component organization#GO:0016043;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;organelle organization#GO:0006996;endosome transport via multivesicular body sorting pathway#GO:0032509;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;leaflet of membrane bilayer#GO:0097478;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;side of membrane#GO:0098552;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cytoplasmic side of membrane#GO:0098562 membrane traffic protein#PC00150 HUMAN|HGNC=37179|UniProtKB=Q6QN14 Q6QN14 USP17L6P PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=7573|UniProtKB=P11055 P11055 MYH3 PTHR45615:SF6 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-3 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=7804|UniProtKB=P23511 P23511 NFYA PTHR12632:SF6 TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT ALPHA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 HUMAN|HGNC=2683|UniProtKB=Q96EP5 Q96EP5 DAZAP1 PTHR48027:SF12 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED DAZ-ASSOCIATED PROTEIN 1 HUMAN|HGNC=5563|UniProtKB=A0A075B7D0 A0A075B7D0 IGHV1OR15-1 PTHR23266:SF359 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=15982|UniProtKB=Q8IWT3 Q8IWT3 CUL9 PTHR22771:SF2 CULLIN AND GALACTOSE-BINDING DOMAIN-CONTAINING CULLIN-9 HUMAN|HGNC=18798|UniProtKB=Q8WWI5 Q8WWI5 SLC44A1 PTHR12385:SF56 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 1 ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;transporter activity#GO:0005215;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;choline transport#GO:0015871;organic cation transport#GO:0015695;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;cation transport#GO:0006812;cellular process#GO:0009987 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=38695|UniProtKB=P0CJ79 P0CJ79 ZNF888 PTHR24377:SF853 IP01015P-RELATED ZINC FINGER PROTEIN 888 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=973|UniProtKB=O75815 O75815 BCAR3 PTHR14247:SF10 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of protein modification process#GO:0031401;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;positive regulation of phosphorylation#GO:0042327;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=12407|UniProtKB=P68366 P68366 TUBA4A PTHR11588:SF53 TUBULIN TUBULIN ALPHA-4A CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cell cycle#GO:0007049;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 HUMAN|HGNC=240|UniProtKB=O60503 O60503 ADCY9 PTHR45627:SF8 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 9 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 HUMAN|HGNC=1502|UniProtKB=P31944 P31944 CASP14 PTHR10454:SF131 CASPASE CASPASE-14-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of cellular protein metabolic process#GO:0032270;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;positive regulation of cell death#GO:0010942;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=30297|UniProtKB=Q9P258 Q9P258 RCC2 PTHR46207:SF1 PROTEIN RCC2 PROTEIN RCC2 HUMAN|HGNC=23623|UniProtKB=Q8TDV2 Q8TDV2 GPR148 PTHR26451:SF928 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN G-PROTEIN COUPLED RECEPTOR 148-RELATED HUMAN|HGNC=17680|UniProtKB=Q9NYW8 Q9NYW8 RBAK PTHR24392:SF18 ZINC FINGER PROTEIN RB-ASSOCIATED KRAB ZINC FINGER PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=22004|UniProtKB=A6NGB9 A6NGB9 WIPF3 PTHR23202:SF31 WASP INTERACTING PROTEIN-RELATED WAS/WASL-INTERACTING PROTEIN FAMILY MEMBER 3 movement of cell or subcellular component#GO:0006928;actin filament-based process#GO:0030029;cellular process#GO:0009987 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=2326|UniProtKB=Q9UKF6 Q9UKF6 CPSF3 PTHR11203:SF11 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;heterocyclic compound binding#GO:1901363;exonuclease activity#GO:0004527 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage factor complex#GO:0005849;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847 RNA processing factor#PC00147 HUMAN|HGNC=4471|UniProtKB=Q13304 Q13304 GPR17 PTHR24232:SF44 G-PROTEIN COUPLED RECEPTOR URACIL NUCLEOTIDE/CYSTEINYL LEUKOTRIENE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=21339|UniProtKB=O60522 O60522 TDRD6 PTHR22948:SF15 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 6 scaffold/adaptor protein#PC00226 HUMAN|HGNC=12527|UniProtKB=Q16851 Q16851 UGP2 PTHR43511:SF4 FAMILY NOT NAMED UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE HUMAN|HGNC=5918|UniProtKB=A0A075B6K5 A0A075B6K5 IGLV3-9 PTHR23267:SF443 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-9 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=26236|UniProtKB=A4FU49 A4FU49 SH3D21 PTHR14167:SF28 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING PROTEIN 21 HUMAN|HGNC=10492|UniProtKB=P29034 P29034 S100A2 PTHR11639:SF59 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calmodulin-related#PC00061 HUMAN|HGNC=20798|UniProtKB=P78383 P78383 SLC35B1 PTHR10778:SF10 SOLUTE CARRIER FAMILY 35 MEMBER B SOLUTE CARRIER FAMILY 35 MEMBER B1 carbohydrate derivative transmembrane transporter activity#GO:1901505;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;UDP-galactose transmembrane transporter activity#GO:0005459;ion transmembrane transporter activity#GO:0015075;nucleobase-containing compound transmembrane transporter activity#GO:0015932;pyrimidine nucleotide-sugar transmembrane transporter activity#GO:0015165;nucleotide-sugar transmembrane transporter activity#GO:0005338;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;nucleotide-sugar transmembrane transport#GO:0015780;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;anion transport#GO:0006820;pyrimidine nucleotide-sugar transmembrane transport#GO:0090481;carbohydrate derivative transport#GO:1901264 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 secondary carrier transporter#PC00258 HUMAN|HGNC=26673|UniProtKB=Q8IWY8 Q8IWY8 ZSCAN29 PTHR23226:SF184 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 29 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25847|UniProtKB=Q9H832 Q9H832 UBE2Z PTHR46116:SF26 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME UBIQUITIN-CONJUGATING ENZYME E2 Z cysteine-type peptidase activity#GO:0008234;peptidase inhibitor activity#GO:0030414;ubiquitin-protein transferase activity#GO:0004842;protease binding#GO:0002020;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;hydrolase activity#GO:0016787;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of programmed cell death#GO:0043069;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;programmed cell death#GO:0012501;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523;negative regulation of apoptotic process#GO:0043066;regulation of programmed cell death#GO:0043067 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=14598|UniProtKB=Q96T52 Q96T52 IMMP2L PTHR46041:SF2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;mitochondrial protein processing#GO:0034982;mitochondrial respiratory chain complex assembly#GO:0033108;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;establishment of protein localization#GO:0045184;protein processing#GO:0016485;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein processing involved in protein targeting to mitochondrion#GO:0006627;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;cellular process#GO:0009987;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 protease#PC00190 HUMAN|HGNC=2200|UniProtKB=P02458 P02458 COL2A1 PTHR24023:SF58 COLLAGEN ALPHA COLLAGEN ALPHA-1(II) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 animal organ development#GO:0048513;collagen fibril organization#GO:0030199;multicellular organism development#GO:0007275;developmental process#GO:0032502;cellular component organization#GO:0016043;skeletal system development#GO:0001501;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;system development#GO:0048731;embryonic organ development#GO:0048568;cellular component organization or biogenesis#GO:0071840;embryo development#GO:0009790;extracellular structure organization#GO:0043062;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501 extracellular matrix#GO:0031012;collagen trimer#GO:0005581;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=26368|UniProtKB=Q4G0Z9 Q4G0Z9 MCMDC2 PTHR11630:SF75 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER MINICHROMOSOME MAINTENANCE DOMAIN-CONTAINING PROTEIN 2 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 protein-containing complex#GO:0032991;MCM core complex#GO:0097373;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=4466|UniProtKB=P47775 P47775 GPR12 PTHR22750:SF8 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 12 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=13452|UniProtKB=Q96R06 Q96R06 SPAG5 PTHR15347:SF1 SPERM-ASSOCIATED ANTIGEN 5 SPERM-ASSOCIATED ANTIGEN 5 HUMAN|HGNC=10577|UniProtKB=Q93045 Q93045 STMN2 PTHR10104:SF18 STATHMIN STATHMIN-2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cellular protein complex disassembly#GO:0043624;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;distal axon#GO:0150034;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;growth cone#GO:0030426;axon#GO:0030424;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 HUMAN|HGNC=15722|UniProtKB=Q8WXQ8 Q8WXQ8 CPA5 PTHR11705:SF16 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B CARBOXYPEPTIDASE A5 hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=1509|UniProtKB=Q14790 Q14790 CASP8 PTHR10454:SF162 CASPASE CASPASE-8 cysteine-type peptidase activity#GO:0008234;binding#GO:0005488;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;protein binding#GO:0005515;cysteine-type endopeptidase activity involved in apoptotic process#GO:0097153;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of cellular protein metabolic process#GO:0032270;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;positive regulation of cell death#GO:0010942;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protease#PC00190 FAS signaling pathway#P00020>Caspase8#P00594;Apoptosis signaling pathway#P00006>Caspase 8#P00299;Huntington disease#P00029>Pro-caspase 8#P00767;FAS signaling pathway#P00020>Pro-Caspase8#P00604;Huntington disease#P00029>Caspase 8#P00808 HUMAN|HGNC=10834|UniProtKB=Q9NR46 Q9NR46 SH3GLB2 PTHR14167:SF68 SH3 DOMAIN-CONTAINING ENDOPHILIN-B2 HUMAN|HGNC=11279|UniProtKB=Q14534 Q14534 SQLE PTHR10835:SF0 SQUALENE MONOOXYGENASE SQUALENE MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;monooxygenase activity#GO:0004497 sterol metabolic process#GO:0016125;organic hydroxy compound metabolic process#GO:1901615;steroid metabolic process#GO:0008202;lipid metabolic process#GO:0006629;organic cyclic compound metabolic process#GO:1901360;organic hydroxy compound biosynthetic process#GO:1901617;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;lipid biosynthetic process#GO:0008610;steroid biosynthetic process#GO:0006694;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;sterol biosynthetic process#GO:0016126;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 oxygenase#PC00177 Cholesterol biosynthesis#P00014>Squalene monooxygenas#P00494 HUMAN|HGNC=40022|UniProtKB=A6NMD0 A6NMD0 IFITM10 PTHR13999:SF9 INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 10 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=8079|UniProtKB=Q6ZUT3 Q6ZUT3 FRMD7 PTHR45858:SF1 FERM DOMAIN CONTAINING PROTEIN FERM DOMAIN-CONTAINING PROTEIN 7 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Rac GTPase binding#GO:0048365;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 HUMAN|HGNC=30886|UniProtKB=Q6NSW5 Q6NSW5 DENND10P1 PTHR28544:SF1 PROTEIN FAM45A-RELATED DENN DOMAIN-CONTAINING PROTEIN 10-RELATED HUMAN|HGNC=9602|UniProtKB=P43119 P43119 PTGIR PTHR11866:SF7 G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER PROSTACYCLIN RECEPTOR signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;organic acid binding#GO:0043177;transmembrane signaling receptor activity#GO:0004888 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;cell population proliferation#GO:0008283;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of intracellular signal transduction#GO:1902531;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;negative regulation of cell population proliferation#GO:0008285;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;regulation of cell population proliferation#GO:0042127;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Gonadotropin-releasing hormone receptor pathway#P06664>PG Rcs#P06836 HUMAN|HGNC=2973|UniProtKB=O00429 O00429 DNM1L PTHR11566:SF39 DYNAMIN DYNAMIN-1-LIKE PROTEIN pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;apoptotic mitochondrial changes#GO:0008637;regulation of catabolic process#GO:0009894;membrane organization#GO:0061024;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;autophagy of mitochondrion#GO:0000422;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;regulation of mitochondrion organization#GO:0010821;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein-containing complex subunit organization#GO:0043933;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;membrane fission#GO:0090148;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organelle disassembly#GO:1903008;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitochondrion distribution#GO:0048311;membrane fusion#GO:0061025;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein polymerization#GO:0051258;organelle fission#GO:0048285;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;mitochondrial fission#GO:0000266;regulation of cellular metabolic process#GO:0031323 envelope#GO:0031975;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 HUMAN|HGNC=18356|UniProtKB=Q8TDN7 Q8TDN7 ACER1 PTHR46139:SF2 ALKALINE CERAMIDASE ALKALINE CERAMIDASE 1 HUMAN|HGNC=21315|UniProtKB=Q8IW70 Q8IW70 TMEM151B PTHR31893:SF4 TRANSMEMBRANE PROTEIN 151 HOMOLOG TRANSMEMBRANE PROTEIN 151B HUMAN|HGNC=26866|UniProtKB=Q8IYK2 Q8IYK2 CCDC105 PTHR35081:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 105 COILED-COIL DOMAIN-CONTAINING PROTEIN 105 HUMAN|HGNC=6610|UniProtKB=P55344 P55344 LIM2 PTHR10671:SF9 EPITHELIAL MEMBRANE PROTEIN-RELATED LENS FIBER MEMBRANE INTRINSIC PROTEIN cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=13488|UniProtKB=Q9UN37 Q9UN37 VPS4A PTHR23074:SF161 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;ATPase activity#GO:0016887 endosomal transport#GO:0016197;cellular localization#GO:0051641;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vacuole organization#GO:0007033;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cytoskeleton organization#GO:0007010;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cytoplasmic microtubule organization#GO:0031122 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=10883|UniProtKB=Q14190 Q14190 SIM2 PTHR23043:SF19 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA SINGLE-MINDED HOMOLOG 2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=2615|UniProtKB=P20813 P20813 CYP2B6 PTHR24300:SF153 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 2B6 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 Bupropion degradation#P05729>Cytochrome P450 2B6#P05742 HUMAN|HGNC=29592|UniProtKB=Q8IXB3 Q8IXB3 TRARG1 PTHR14948:SF1 NG5 TRAFFICKING REGULATOR OF GLUT4 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=28857|UniProtKB=O95780 O95780 ZNF682 PTHR24384:SF116 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 682 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=28678|UniProtKB=Q8IVU9 Q8IVU9 CABCOCO1 PTHR28457:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 189 CILIARY-ASSOCIATED CALCIUM-BINDING COILED-COIL PROTEIN 1 HUMAN|HGNC=30712|UniProtKB=Q6UWH6 Q6UWH6 TEX261 PTHR13144:SF0 TEX261 PROTEIN PROTEIN TEX261 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;integral component of membrane#GO:0016021;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 HUMAN|HGNC=8143|UniProtKB=Q14982 Q14982 OPCML PTHR42757:SF17 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED OPIOID-BINDING PROTEIN/CELL ADHESION MOLECULE immunoglobulin#PC00123 HUMAN|HGNC=28853|UniProtKB=Q8TAC2 Q8TAC2 JOSD2 PTHR13291:SF2 JOSEPHIN 1, 2 JOSEPHIN-2 hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081 HUMAN|HGNC=23405|UniProtKB=Q9H2I8 Q9H2I8 LRMDA PTHR46282:SF2 LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN HUMAN|HGNC=20373|UniProtKB=Q9NZD8 Q9NZD8 SPG21 PTHR15913:SF0 ACID CLUSTER PROTEIN 33 MASPARDIN HUMAN|HGNC=12823|UniProtKB=O43895 O43895 XPNPEP2 PTHR43763:SF4 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 2 protease#PC00190 HUMAN|HGNC=25897|UniProtKB=Q8NA29 Q8NA29 MFSD2A PTHR11328:SF29 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN SODIUM-DEPENDENT LYSOPHOSPHATIDYLCHOLINE SYMPORTER 1 carbohydrate derivative transmembrane transporter activity#GO:1901505;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;organophosphate ester transmembrane transporter activity#GO:0015605;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;lipid transporter activity#GO:0005319;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;phospholipid transporter activity#GO:0005548;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;transport#GO:0006810 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=23137|UniProtKB=Q8NC42 Q8NC42 RNF149 PTHR22765:SF39 RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF149 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=23590|UniProtKB=B3EWG6 B3EWG6 FAM25G PTHR34994:SF1 PROTEIN FAM25A-RELATED PROTEIN FAM25A-RELATED HUMAN|HGNC=16126|UniProtKB=A1Z1Q3 A1Z1Q3 MACROD2 PTHR11106:SF104 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED ADP-RIBOSE GLYCOHYDROLASE MACROD2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;cellular protein metabolic process#GO:0044267;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26818|UniProtKB=Q68D10 Q68D10 SPTY2D1 PTHR22691:SF8 YEAST SPT2-RELATED PROTEIN SPT2 HOMOLOG heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;nucleic acid binding#GO:0003676;histone binding#GO:0042393;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular component biogenesis#GO:0044085;histone exchange#GO:0043486;nucleosome assembly#GO:0006334;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;regulation of chromatin assembly or disassembly#GO:0001672;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;regulation of chromatin organization#GO:1902275;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;DNA packaging#GO:0006323;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of chromatin assembly#GO:0010847;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;chromatin assembly#GO:0031497;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=25751|UniProtKB=Q7Z392 Q7Z392 TRAPPC11 PTHR14374:SF0 FOIE GRAS TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11 HUMAN|HGNC=15082|UniProtKB=Q8NGT7 Q8NGT7 OR2A12 PTHR26453:SF50 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2A12 transmembrane signal receptor#PC00197 HUMAN|HGNC=11881|UniProtKB=P62328 P62328 TMSB4X PTHR12021:SF20 THYMOSIN BETA THYMOSIN BETA-4 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488;actin monomer binding#GO:0003785 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;regulation of locomotion#GO:0040012;cellular protein localization#GO:0034613;protein-containing complex assembly#GO:0065003;regulation of localization#GO:0032879;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell migration#GO:0030334;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;regulation of cellular component movement#GO:0051270;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of cell motility#GO:2000145;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;localization of cell#GO:0051674;actin polymerization or depolymerization#GO:0008154;cell motility#GO:0048870;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;protein localization#GO:0008104;localization#GO:0051179;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2350|UniProtKB=O60519 O60519 CREBL2 PTHR21051:SF4 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=2720|UniProtKB=Q9ULH1 Q9ULH1 ASAP1 PTHR45854:SF2 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 Integrin signalling pathway#P00034>ASAP1#P00909 HUMAN|HGNC=6182|UniProtKB=Q14573 Q14573 ITPR3 PTHR13715:SF51 RYANODINE RECEPTOR AND IP3 RECEPTOR INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 3 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;metal ion binding#GO:0046872;ion transmembrane transporter activity#GO:0015075;phospholipid binding#GO:0005543;transporter activity#GO:0005215;channel activity#GO:0015267;cation binding#GO:0043169;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;sequestering of calcium ion#GO:0051208;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;negative regulation of cellular process#GO:0048523;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;release of sequestered calcium ion into cytosol#GO:0051209;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;regulation of cellular localization#GO:0060341;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065;negative regulation of sequestering of calcium ion#GO:0051283 bounding membrane of organelle#GO:0098588;sarcoplasmic reticulum#GO:0016529;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;secretory granule#GO:0030141;sarcoplasm#GO:0016528;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783;secretory vesicle#GO:0099503;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Histamine H1 receptor mediated signaling pathway#P04385>IP3R#P04486;Endothelin signaling pathway#P00019>IP3 R#P00590;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>IP3R#P01064;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IP3R#P00842;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>IP3 channel#P00735;Gonadotropin-releasing hormone receptor pathway#P06664>IP3R#P06768;B cell activation#P00010>IP3R#P00398;Wnt signaling pathway#P00057>IP3 Gated Calcium Channel#P01426;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>IP3R#P05932;PDGF signaling pathway#P00047>IP3 receptor#P01160 HUMAN|HGNC=26736|UniProtKB=Q5U5R9 Q5U5R9 HECTD2 PTHR45622:SF40 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HECTD2-RELATED ubiquitin-protein ligase#PC00234 EGF receptor signaling pathway#P00018>RKIP#P00548;Ubiquitin proteasome pathway#P00060>E3#P01490 HUMAN|HGNC=20491|UniProtKB=Q8N9Y4 Q8N9Y4 FAM181A PTHR33766:SF1 PROTEIN FAM181B PROTEIN FAM181A HUMAN|HGNC=13011|UniProtKB=Q9P2Y4 Q9P2Y4 ZNF219 PTHR45925:SF1 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 219 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9753|UniProtKB=Q16769 Q16769 QPCT PTHR12283:SF5 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE cation binding#GO:0043169;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=6062|UniProtKB=Q9UK53 Q9UK53 ING1 PTHR10333:SF85 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 1 protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=8482|UniProtKB=Q9GZM6 Q9GZM6 OR8D2 PTHR48018:SF173 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8D2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=17369|UniProtKB=Q9ULW3 Q9ULW3 ABT1 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex assembly#GO:0022618;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cleavage involved in rRNA processing#GO:0000469;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organelle organization#GO:0006996;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;endonucleolytic cleavage involved in rRNA processing#GO:0000478;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=48369|UniProtKB=B4DZS4 B4DZS4 TCP11X1 PTHR12832:SF21 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 T-COMPLEX PROTEIN 11 X-LINKED PROTEIN 1-RELATED male gamete generation#GO:0048232;signal transduction#GO:0007165;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;spermatid differentiation#GO:0048515;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;spermatogenesis#GO:0007283;reproductive process#GO:0022414;regulation of multi-organism process#GO:0043900;intracellular signal transduction#GO:0035556;multi-organism reproductive process#GO:0044703;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609;sperm capacitation#GO:0048240;germ cell development#GO:0007281;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;gamete generation#GO:0007276;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;multicellular organism reproduction#GO:0032504;cell communication#GO:0007154;regulation of reproductive process#GO:2000241;cellular process#GO:0009987;multi-organism process#GO:0051704;developmental process involved in reproduction#GO:0003006;cell development#GO:0048468;spermatid development#GO:0007286;response to stimulus#GO:0050896;reproduction#GO:0000003;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 supramolecular complex#GO:0099080;axoneme#GO:0005930;acrosomal vesicle#GO:0001669;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;secretory granule#GO:0030141;cytoplasmic microtubule#GO:0005881;vacuole#GO:0005773;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;B axonemal microtubule#GO:0097650;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;intracellular vesicle#GO:0097708;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;cytoplasmic vesicle#GO:0031410;dynein complex#GO:0030286;cytoskeleton#GO:0005856;secretory vesicle#GO:0099503;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=19030|UniProtKB=Q8IZF2 Q8IZF2 ADGRF5 PTHR45813:SF4 FAMILY NOT NAMED ADHESION G PROTEIN-COUPLED RECEPTOR F5 HUMAN|HGNC=4965|UniProtKB=P01893 P01893 HLA-H PTHR16675:SF256 MHC CLASS I-RELATED HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN H-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;amide binding#GO:0033218;peptide binding#GO:0042277 immune response#GO:0006955;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;antigen processing and presentation#GO:0019882;positive regulation of immune system process#GO:0002684;T cell mediated immunity#GO:0002456;positive regulation of adaptive immune response#GO:0002821;cellular process#GO:0009987;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte mediated immunity#GO:0002708;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;positive regulation of immune response#GO:0050778;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;adaptive immune response#GO:0002250;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;regulation of lymphocyte mediated immunity#GO:0002706;regulation of immune system process#GO:0002682;regulation of adaptive immune response#GO:0002819;positive regulation of immune effector process#GO:0002699;positive regulation of biological process#GO:0048518;immune effector process#GO:0002252 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=6824|UniProtKB=Q16706 Q16706 MAN2A1 PTHR11607:SF3 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 HUMAN|HGNC=10504|UniProtKB=P25815 P25815 S100P PTHR11639:SF139 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-P localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;multicellular organismal process#GO:0032501;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;endothelial cell migration#GO:0043542;locomotion#GO:0040011 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;extracellular region#GO:0005576;intracellular organelle lumen#GO:0070013;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 calmodulin-related#PC00061 HUMAN|HGNC=18448|UniProtKB=Q96FI4 Q96FI4 NEIL1 PTHR22993:SF27 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE ENDONUCLEASE 8-LIKE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 DNA glycosylase#PC00010 HUMAN|HGNC=23570|UniProtKB=Q8TAL5 Q8TAL5 C9orf43 PTHR36130:SF1 RIKEN CDNA 4933430I17 GENE RIKEN CDNA 4933430I17 GENE HUMAN|HGNC=9319|UniProtKB=P60510 P60510 PPP4C PTHR45619:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 4 CATALYTIC SUBUNIT protein phosphatase#PC00195 EGF receptor signaling pathway#P00018>PP2A#P00547;FGF signaling pathway#P00021>PP2A#P00629 HUMAN|HGNC=20061|UniProtKB=Q9P2H5 Q9P2H5 USP35 PTHR24006:SF660 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 35 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=26779|UniProtKB=A1L429 A1L429 GAGE12C PTHR14047:SF30 P ANTIGEN FAMILY MEMBER 5-RELATED G ANTIGEN 1-RELATED HUMAN|HGNC=9246|UniProtKB=O75334 O75334 PPFIA2 PTHR12587:SF6 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA-2 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cell junction#GO:0030054;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical entity#GO:0110165;presynaptic active zone#GO:0048786 HUMAN|HGNC=18184|UniProtKB=Q96GG9 Q96GG9 DCUN1D1 PTHR12281:SF10 RP42 RELATED DCN1-LIKE PROTEIN 1 enzyme binding#GO:0019899;ubiquitin-like protein conjugating enzyme binding#GO:0044390;protein binding#GO:0005515;binding#GO:0005488 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=6948|UniProtKB=P33992 P33992 MCM5 PTHR11630:SF42 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM5 DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;single-stranded DNA binding#GO:0003697;binding#GO:0005488;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;DNA-dependent ATPase activity#GO:0008094;sequence-specific double-stranded DNA binding#GO:1990837;pyrophosphatase activity#GO:0016462;sequence-specific DNA binding#GO:0043565;3'-5' DNA helicase activity#GO:0043138;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;single-stranded DNA helicase activity#GO:0017116;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;protein-containing complex subunit organization#GO:0043933;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;nuclear DNA replication#GO:0033260;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;pre-replicative complex assembly involved in nuclear cell cycle DNA replication#GO:0006267;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;organic cyclic compound biosynthetic process#GO:1901362;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;DNA biosynthetic process#GO:0071897;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;MCM core complex#GO:0097373;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 Parkinson disease#P00049>Hsp70#P01208;Apoptosis signaling pathway#P00006>HSP70#P00321 HUMAN|HGNC=17649|UniProtKB=Q9HBV1 Q9HBV1 POPDC3 PTHR12101:SF18 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 3 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 skeletal muscle organ development#GO:0060538;cellular developmental process#GO:0048869;muscle organ development#GO:0007517;heart development#GO:0007507;muscle cell differentiation#GO:0042692;circulatory system development#GO:0072359;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular process#GO:0009987;tissue development#GO:0009888;muscle tissue development#GO:0060537;muscle structure development#GO:0061061;cell differentiation#GO:0030154;striated muscle cell differentiation#GO:0051146;system development#GO:0048731;striated muscle tissue development#GO:0014706;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;skeletal muscle tissue development#GO:0007519 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;sarcolemma#GO:0042383;plasma membrane#GO:0005886 HUMAN|HGNC=22988|UniProtKB=Q9BWV2 Q9BWV2 SPATA9 PTHR35669:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 9 SPERMATOGENESIS-ASSOCIATED PROTEIN 9 HUMAN|Ensembl=ENSG00000285891|UniProtKB=A0A3B3IT52 A0A3B3IT52 LOC102724657 PTHR31512:SF2 GENE 12569-RELATED GENE 12569-RELATED HUMAN|HGNC=12555|UniProtKB=Q16880 Q16880 UGT8 PTHR48043:SF54 EG:EG0003.4 PROTEIN-RELATED 2-HYDROXYACYLSPHINGOSINE 1-BETA-GALACTOSYLTRANSFERASE transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=2703|UniProtKB=P42126 P42126 ECI1 PTHR11941:SF45 ENOYL-COA HYDRATASE-RELATED ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;lipid oxidation#GO:0034440;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 hydratase#PC00120 HUMAN|HGNC=30178|UniProtKB=Q9Y570 Q9Y570 PPME1 PTHR14189:SF0 PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED PROTEIN PHOSPHATASE METHYLESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein demethylation#GO:0006482;cellular protein metabolic process#GO:0044267;demethylation#GO:0070988;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein modifying enzyme#PC00260 HUMAN|HGNC=21689|UniProtKB=Q9Y3D6 Q9Y3D6 FIS1 PTHR13247:SF16 TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11 MITOCHONDRIAL FISSION 1 PROTEIN apoptotic mitochondrial changes#GO:0008637;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;cellular process#GO:0009987;organelle disassembly#GO:1903008;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;organelle fission#GO:0048285;mitochondrion organization#GO:0007005;peroxisome organization#GO:0007031;autophagy#GO:0006914;mitochondrial fission#GO:0000266;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;microbody membrane#GO:0031903;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;integral component of peroxisomal membrane#GO:0005779;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;integral component of mitochondrial outer membrane#GO:0031307 HUMAN|HGNC=21617|UniProtKB=Q8N3L3 Q8N3L3 TXLNB PTHR16127:SF10 TAXILIN BETA-TAXILIN membrane traffic protein#PC00150 HUMAN|HGNC=20434|UniProtKB=Q86YW5 Q86YW5 TREML1 PTHR11860:SF37 POLYMERIC-IMMUNOGLOBULIN RECEPTOR TREM-LIKE TRANSCRIPT 1 PROTEIN immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=33114|UniProtKB=Q6PG37 Q6PG37 ZNF790 PTHR24377:SF719 IP01015P-RELATED ZINC FINGER PROTEIN 790 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11962|UniProtKB=O15417 O15417 TNRC18 PTHR12505:SF21 PHD FINGER TRANSCRIPTION FACTOR TRINUCLEOTIDE REPEAT-CONTAINING GENE 18 PROTEIN DNA-binding transcription factor#PC00218 HUMAN|HGNC=21285|UniProtKB=Q96PN6 Q96PN6 ADCY10 PTHR16305:SF32 TESTICULAR SOLUBLE ADENYLYL CYCLASE ADENYLATE CYCLASE TYPE 10 adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Metabotropic glutamate receptor group III pathway#P00039>AC#P01043;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AC#P01082;Metabotropic glutamate receptor group II pathway#P00040>AC#P01052 HUMAN|HGNC=16047|UniProtKB=Q9BSG0 Q9BSG0 PRADC1 PTHR22702:SF3 PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=29296|UniProtKB=Q8IYE0 Q8IYE0 CCDC146 PTHR32083:SF34 CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 146 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular#GO:0005622;intracellular organelle#GO:0043229 structural protein#PC00211 HUMAN|HGNC=15587|UniProtKB=Q4VX76 Q4VX76 SYTL3 PTHR45716:SF1 BITESIZE, ISOFORM I SYNAPTOTAGMIN-LIKE PROTEIN 3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 HUMAN|HGNC=955|UniProtKB=Q9HBU1 Q9HBU1 BARX1 PTHR24330:SF12 HOMEOBOX PROTEIN BARH-LIKE HOMEOBOX PROTEIN BARH-LIKE 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=23394|UniProtKB=Q5TZJ5 Q5TZJ5 SPATA31A1 PTHR21859:SF55 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31A1-RELATED HUMAN|HGNC=30439|UniProtKB=Q7Z4S9 Q7Z4S9 SH2D6 PTHR14098:SF16 SH2 DOMAIN CONTAINING PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 6 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=15480|UniProtKB=Q9NSV4 Q9NSV4 DIAPH3 PTHR45691:SF9 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS HOMOLOG 3 Cytoskeletal regulation by Rho GTPase#P00016>mDia#P00510 HUMAN|HGNC=26164|UniProtKB=Q6N069 Q6N069 NAA16 PTHR22767:SF5 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 16, NATA AUXILIARY SUBUNIT transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;N-acyltransferase activity#GO:0016410 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;N-terminal protein amino acid acetylation#GO:0006474;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 acetyltransferase#PC00038 HUMAN|HGNC=4506|UniProtKB=Q13585 Q13585 GPR50 PTHR24228:SF56 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR MELATONIN-RELATED RECEPTOR regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 HUMAN|HGNC=9713|UniProtKB=P40855 P40855 PEX19 PTHR12774:SF2 PEROXISOMAL BIOGENESIS FACTOR 19 PEROXISOMAL BIOGENESIS FACTOR 19 signal sequence binding#GO:0005048;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein targeting to peroxisome#GO:0006625;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein localization to peroxisome#GO:0072662;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;protein targeting to membrane#GO:0006612;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;microbody membrane#GO:0031903;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 membrane traffic protein#PC00150 HUMAN|HGNC=18365|UniProtKB=Q8IZI9 Q8IZI9 IFNL3 PTHR31943:SF1 INTERLEUKIN-28 AND 29 INTERFERON LAMBDA-2-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;immune response#GO:0006955;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;innate immune response#GO:0045087;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 interleukin superfamily#PC00128 HUMAN|HGNC=2663|UniProtKB=Q9UI36 Q9UI36 DACH1 PTHR12577:SF14 DACHSHUND DACHSHUND HOMOLOG 1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=14415|UniProtKB=Q9GZR5 Q9GZR5 ELOVL4 PTHR11157:SF12 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 4 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;very long-chain fatty acid metabolic process#GO:0000038;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=12996|UniProtKB=O95201 O95201 ZNF205 PTHR23226:SF77 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 205 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=10899|UniProtKB=P63208 P63208 SKP1 PTHR11165:SF120 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=17293|UniProtKB=Q9BZL6 Q9BZL6 PRKD2 PTHR22968:SF12 PROTEIN KINASE C, MU SERINE/THREONINE-PROTEIN KINASE D2 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167 CCKR signaling map#P06959>PRKD2#P07216;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;EGF receptor signaling pathway#P00018>PKC#P00565 HUMAN|HGNC=18411|UniProtKB=Q3KNW1 Q3KNW1 SNAI3 PTHR24388:SF40 ZINC FINGER PROTEIN ZINC FINGER PROTEIN SNAI3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=3341|UniProtKB=Q04743 Q04743 EMX2 PTHR24339:SF25 HOMEOBOX PROTEIN EMX-RELATED HOMEOBOX PROTEIN EMX2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;brain development#GO:0007420;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;neurogenesis#GO:0022008;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=33227|UniProtKB=B3SHH9 B3SHH9 TMEM114 PTHR20516:SF2 TRANSMEMBRANE PROTEIN 114/235 FAMILY MEMBER TRANSMEMBRANE PROTEIN 114 plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;apical part of cell#GO:0045177;apical plasma membrane#GO:0016324 HUMAN|HGNC=10998|UniProtKB=Q6P1M0 Q6P1M0 SLC27A4 PTHR43107:SF11 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 4 ligase activity#GO:0016874;transporter activity#GO:0005215;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;lipid transporter activity#GO:0005319 lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;macromolecule localization#GO:0033036;organic acid transport#GO:0015849;transport#GO:0006810;very long-chain fatty acid metabolic process#GO:0000038;lipid catabolic process#GO:0016042;response to extracellular stimulus#GO:0009991;lipid transport#GO:0006869;response to nutrient#GO:0007584;organic substance transport#GO:0071702;establishment of localization#GO:0051234;anion transport#GO:0006820;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;organic anion transport#GO:0015711;ion transport#GO:0006811;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;long-chain fatty acid transport#GO:0015909;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 microvillus#GO:0005902;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;actin-based cell projection#GO:0098858;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;endomembrane system#GO:0012505;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;cell projection#GO:0042995;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|Ensembl=ENSG00000275949|UniProtKB=A0A0G2JMH3 A0A0G2JMH3 LOC107984156 PTHR11711:SF347 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 17-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 G-protein#PC00020 HUMAN|HGNC=971|UniProtKB=P56945 P56945 BCAR1 PTHR10654:SF15 CAS SCAFFOLDING PROTEIN BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 1 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;actin cytoskeleton reorganization#GO:0031532;enzyme linked receptor protein signaling pathway#GO:0007167;localization of cell#GO:0051674;cell motility#GO:0048870;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;supramolecular fiber organization#GO:0097435;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell migration#GO:0016477;locomotion#GO:0040011;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;anchoring junction#GO:0070161;intracellular#GO:0005622;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 CCKR signaling map#P06959>CAS#P07180;Integrin signalling pathway#P00034>p130CAS#P00908 HUMAN|HGNC=7043|UniProtKB=O43451 O43451 MGAM PTHR22762:SF63 ALPHA-GLUCOSIDASE MALTASE-GLUCOAMYLASE, INTESTINAL glucosidase#PC00108 HUMAN|HGNC=14061|UniProtKB=O60711 O60711 LPXN PTHR24216:SF23 PAXILLIN-RELATED LEUPAXIN molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;B cell receptor signaling pathway#GO:0050853;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;anatomical structure morphogenesis#GO:0009653;regulation of signal transduction#GO:0009966;immune response-activating signal transduction#GO:0002757;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;regulation of immune response#GO:0050776;localization of cell#GO:0051674;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;endothelial cell migration#GO:0043542;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;movement of cell or subcellular component#GO:0006928;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;locomotion#GO:0040011;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;regulation of signaling#GO:0023051;biological adhesion#GO:0022610;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;regulation of immune system process#GO:0002682;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cell morphogenesis involved in differentiation#GO:0000904;negative regulation of response to stimulus#GO:0048585;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cellular process#GO:0009987;localization#GO:0051179;cell development#GO:0048468;response to stimulus#GO:0050896;immune system process#GO:0002376;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;cell migration#GO:0016477 cytoplasm#GO:0005737;anchoring junction#GO:0070161;intracellular#GO:0005622;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 Angiogenesis#P00005>Paxillin#P00194;VEGF signaling pathway#P00056>Paxillin#P01418 HUMAN|HGNC=16110|UniProtKB=Q96HY6 Q96HY6 DDRGK1 PTHR48176:SF1 DDRGK DOMAIN-CONTAINING PROTEIN 1 DDRGK DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=6838|UniProtKB=Q9H492 Q9H492 MAP1LC3A PTHR10969:SF14 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3A binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;ubiquitin protein ligase binding#GO:0031625;phospholipid binding#GO:0005543 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular component organization#GO:0016043;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome organization#GO:1905037;autophagosome assembly#GO:0000045;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;whole membrane#GO:0098805 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=15404|UniProtKB=Q8NG94 Q8NG94 OR11H1 PTHR24242:SF201 G-PROTEIN COUPLED RECEPTOR OLFACTORY RECEPTOR 11H1-RELATED G-protein coupled receptor#PC00021 HUMAN|HGNC=17194|UniProtKB=Q9P0J0 Q9P0J0 NDUFA13 PTHR12966:SF0 NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 dehydrogenase#PC00092 HUMAN|HGNC=28364|UniProtKB=Q96L14 Q96L14 CEP170P1 PTHR15715:SF17 CENTROSOMAL PROTEIN OF 170 KDA CENTROSOMAL PROTEIN OF 170 KDA-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=6834|UniProtKB=P27338 P27338 MAOB PTHR43563:SF13 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] B oxidase#PC00175 Dopamine receptor mediated signaling pathway#P05912>MAO#P05963;Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067;5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 HUMAN|HGNC=12373|UniProtKB=P16473 P16473 TSHR PTHR24372:SF0 GLYCOPROTEIN HORMONE RECEPTOR THYROTROPIN RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=1078|UniProtKB=Q13873 Q13873 BMPR2 PTHR23255:SF63 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-2 signaling receptor activity#GO:0038023;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;response to BMP#GO:0071772;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007 receptor complex#GO:0043235;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 Gonadotropin-releasing hormone receptor pathway#P06664>BMPR-IA/IB/II#P06740;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277 HUMAN|HGNC=24538|UniProtKB=Q9BUJ0 Q9BUJ0 ABHD14A PTHR46197:SF1 PROTEIN ABHD14B-LIKE PROTEIN ABHD14A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=17329|UniProtKB=Q9H6Q3 Q9H6Q3 SLA2 PTHR10155:SF6 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SRC-LIKE-ADAPTER 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;regulation of catalytic activity#GO:0050790;cellular response to nitrogen compound#GO:1901699;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;glycerolipid metabolic process#GO:0046486;response to peptide#GO:1901652;regulation of molecular function#GO:0065009;cellular response to insulin stimulus#GO:0032869;phosphorylation#GO:0016310;signaling#GO:0023052;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;cellular metabolic process#GO:0044237;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular process#GO:0009987;cellular response to peptide hormone stimulus#GO:0071375;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;regulation of lipid metabolic process#GO:0019216;cellular lipid metabolic process#GO:0044255;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;phosphatidylinositol phosphorylation#GO:0046854;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase modulator#PC00140 Interleukin signaling pathway#P00036>Src-like#P00991 HUMAN|HGNC=15866|UniProtKB=Q9NV56 Q9NV56 MRGBP PTHR13581:SF5 MRG-BINDING PROTEIN MRG/MORF4L-BINDING PROTEIN regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;histone acetylation#GO:0016573;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;peptidyl-lysine modification#GO:0018205;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=19423|UniProtKB=Q9UNL4 Q9UNL4 ING4 PTHR10333:SF42 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 4 protein binding#GO:0005515;methylated histone binding#GO:0035064;binding#GO:0005488;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=9071|UniProtKB=P00747 P00747 PLG PTHR24261:SF13 PLASMINOGEN-RELATED PLASMINOGEN-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 Blood coagulation#P00011>Plasmin#P00415;Blood coagulation#P00011>Plasminogen#P00408;Plasminogen activating cascade#P00050>Plasminogen#P01255;Plasminogen activating cascade#P00050>Plasmin#P01246 HUMAN|HGNC=26087|UniProtKB=Q7Z4Q2 Q7Z4Q2 HEATR3 PTHR13347:SF1 UNCHARACTERIZED HEAT REPEAT-CONTAINING PROTEIN 3 protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;ribonucleoprotein complex biogenesis#GO:0022613;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;ribosome biogenesis#GO:0042254;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 HUMAN|HGNC=6317|UniProtKB=O43896 O43896 KIF1C PTHR24115:SF322 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF1C pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;ATP-dependent microtubule motor activity, plus-end-directed#GO:0008574;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 localization#GO:0051179;cellular localization#GO:0051641;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987 supramolecular complex#GO:0099080;somatodendritic compartment#GO:0036477;dendrite#GO:0030425;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;dendritic tree#GO:0097447;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;axon#GO:0030424;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;neuron projection#GO:0043005;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 HUMAN|HGNC=31923|UniProtKB=Q86VQ0 Q86VQ0 LCA5 PTHR16650:SF10 C21ORF13-RELATED LEBERCILIN microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=13068|UniProtKB=Q96GC6 Q96GC6 ZNF274 PTHR23226:SF93 ZINC FINGER AND SCAN DOMAIN-CONTAINING NEUROTROPHIN RECEPTOR-INTERACTING FACTOR HOMOLOG cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26987|UniProtKB=Q7Z2F6 Q7Z2F6 ZNF720 PTHR23232:SF100 KRAB DOMAIN C2H2 ZINC FINGER KRAB DOMAIN-CONTAINING PROTEIN ZNF747-RELATED C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=30716|UniProtKB=Q7Z5A4 Q7Z5A4 PRSS42P PTHR24256:SF246 TRYPTASE-RELATED SERINE PROTEASE 42-RELATED serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=12212|UniProtKB=A0A576 A0A576 TRBV3-1 PTHR23268:SF92 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 3-1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=17376|UniProtKB=Q9UIJ7 Q9UIJ7 AK3 PTHR23359:SF68 NUCLEOTIDE KINASE GTP:AMP PHOSPHOTRANSFERASE AK3, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;adenylate kinase activity#GO:0004017;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;nucleoside diphosphate metabolic process#GO:0009132;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 HUMAN|HGNC=11112|UniProtKB=Q8NDV3 Q8NDV3 SMC1B PTHR18937:SF147 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1B HUMAN|HGNC=2321|UniProtKB=P36551 P36551 CPOX PTHR10755:SF0 COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;porphyrin-containing compound metabolic process#GO:0006778;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;heme metabolic process#GO:0042168;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidase#PC00175 Heme biosynthesis#P02746>Coproporphyrinogen Oxidase (oxygen dependent)#P02980 HUMAN|HGNC=9756|UniProtKB=O00391 O00391 QSOX1 PTHR22897:SF6 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE 1 isomerase activity#GO:0016853;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;protein folding#GO:0006457 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 oxidase#PC00175 HUMAN|HGNC=32190|UniProtKB=Q6DKI7 Q6DKI7 PVRIG PTHR39220:SF1 TRANSMEMBRANE PROTEIN PVRIG TRANSMEMBRANE PROTEIN PVRIG HUMAN|HGNC=7554|UniProtKB=Q99417 Q99417 MYCBP PTHR13168:SF2 ASSOCIATE OF C-MYC AMY-1 C-MYC-BINDING PROTEIN transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 PDGF signaling pathway#P00047>c-Myc#P01172 HUMAN|HGNC=2730|UniProtKB=Q08345 Q08345 DDR1 PTHR24416:SF333 TYROSINE-PROTEIN KINASE RECEPTOR EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;collagen binding#GO:0005518;molecular transducer activity#GO:0060089;protein-containing complex binding#GO:0044877;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=9996|UniProtKB=O43566 O43566 RGS14 PTHR45945:SF2 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G-PROTEIN SIGNALING 14 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>RGS#P00833 HUMAN|HGNC=14702|UniProtKB=Q8NGB2 Q8NGB2 OR4C5 PTHR48002:SF13 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4C5 transmembrane signal receptor#PC00197 HUMAN|HGNC=1079|UniProtKB=P51813 P51813 BMX PTHR24418:SF91 TYROSINE-PROTEIN KINASE CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;signal transduction#GO:0007165;activation of immune response#GO:0002253;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;B cell receptor signaling pathway#GO:0050853;peptidyl-amino acid modification#GO:0018193;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;adaptive immune response#GO:0002250;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;immune response-activating signal transduction#GO:0002757;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;immune system process#GO:0002376;peptidyl-tyrosine modification#GO:0018212;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;immune response-activating cell surface receptor signaling pathway#GO:0002429;T cell receptor signaling pathway#GO:0050852 HUMAN|HGNC=6907|UniProtKB=P21941 P21941 MATN1 PTHR24020:SF16 COLLAGEN ALPHA CARTILAGE MATRIX PROTEIN extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=28082|UniProtKB=Q3KQV9 Q3KQV9 UAP1L1 PTHR11952:SF6 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLHEXOSAMINE PYROPHOSPHORYLASE-LIKE PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;uridylyltransferase activity#GO:0070569;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;UDP-N-acetylglucosamine metabolic process#GO:0006047;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;amino sugar metabolic process#GO:0006040;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 HUMAN|HGNC=31653|UniProtKB=Q5VZQ5 Q5VZQ5 TEX36 PTHR35440:SF1 TESTIS-EXPRESSED PROTEIN 36 TESTIS-EXPRESSED PROTEIN 36 HUMAN|HGNC=2038|UniProtKB=P56750 P56750 CLDN17 PTHR12002:SF75 CLAUDIN CLAUDIN-17 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;cell junction organization#GO:0034330;biological adhesion#GO:0022610;cell junction assembly#GO:0034329;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;bicellular tight junction#GO:0005923;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;apical junction complex#GO:0043296;plasma membrane#GO:0005886 tight junction#PC00214 HUMAN|HGNC=7860|UniProtKB=Q16517 Q16517 NNAT PTHR15285:SF0 NEURONATIN NEURONATIN brain development#GO:0007420;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;protein secretion#GO:0009306;regulation of localization#GO:0032879;nervous system development#GO:0007399;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;positive regulation of peptide hormone secretion#GO:0090277;hormone secretion#GO:0046879;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;secretion#GO:0046903;regulation of secretion#GO:0051046;insulin secretion#GO:0030073;central nervous system development#GO:0007417;hormone transport#GO:0009914;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;regulation of peptide hormone secretion#GO:0090276;regulation of protein secretion#GO:0050708;positive regulation of secretion#GO:0051047;positive regulation of transport#GO:0051050;cell communication#GO:0007154;peptide transport#GO:0015833;positive regulation of hormone secretion#GO:0046887;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;establishment of protein localization to extracellular region#GO:0035592;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;multicellular organismal process#GO:0032501;positive regulation of secretion by cell#GO:1903532;protein localization to extracellular region#GO:0071692;regulation of establishment of protein localization#GO:0070201;export from cell#GO:0140352;regulation of peptide transport#GO:0090087;head development#GO:0060322;macromolecule localization#GO:0033036;animal organ development#GO:0048513;positive regulation of protein secretion#GO:0050714;regulation of signaling#GO:0023051;positive regulation of peptide secretion#GO:0002793;developmental process#GO:0032502;transport#GO:0006810;regulation of insulin secretion#GO:0050796;peptide secretion#GO:0002790;amide transport#GO:0042886;system development#GO:0048731;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;peptide hormone secretion#GO:0030072;regulation of hormone secretion#GO:0046883;signal release#GO:0023061;regulation of protein transport#GO:0051223;signaling#GO:0023052;cell-cell signaling#GO:0007267;secretion by cell#GO:0032940;regulation of cell communication#GO:0010646;multicellular organism development#GO:0007275;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;localization#GO:0051179;biological regulation#GO:0065007 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=24838|UniProtKB=Q6UWT2 Q6UWT2 ENHO PTHR38492:SF1 ADROPIN ADROPIN regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of Notch signaling pathway#GO:0008593;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;Notch signaling pathway#GO:0007219 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=17880|UniProtKB=Q8IWU2 Q8IWU2 LMTK2 PTHR24416:SF357 TYROSINE-PROTEIN KINASE RECEPTOR SERINE/THREONINE-PROTEIN KINASE LMTK2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of cellular metabolic process#GO:0031325;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;multicellular organismal process#GO:0032501;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=18360|UniProtKB=Q92551 Q92551 IP6K1 PTHR12400:SF73 INOSITOL POLYPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;organic hydroxy compound biosynthetic process#GO:1901617;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 HUMAN|HGNC=28639|UniProtKB=Q6UWP2 Q6UWP2 DHRS11 PTHR43115:SF4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11 oxidoreductase#PC00176 HUMAN|HGNC=4494|UniProtKB=O15354 O15354 GPR37 PTHR46216:SF3 PROSAPOSIN RECEPTOR GPR37 FAMILY MEMBER PROSAPOSIN RECEPTOR GPR37 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of MAPK cascade#GO:0043408;regulation of adenylate cyclase activity#GO:0045761;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;negative regulation of signal transduction#GO:0009968;cAMP-mediated signaling#GO:0019933;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;second-messenger-mediated signaling#GO:0019932;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;regulation of cyclase activity#GO:0031279;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;negative regulation of response to stimulus#GO:0048585;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;negative regulation of cAMP-mediated signaling#GO:0043951;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;negative regulation of catalytic activity#GO:0043086;cyclic-nucleotide-mediated signaling#GO:0019935;negative regulation of molecular function#GO:0044092 receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Parkinson disease#P00049>Pael-R#P01229 HUMAN|HGNC=697|UniProtKB=Q15041 Q15041 ARL6IP1 PTHR20952:SF0 ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 1 HUMAN|HGNC=16503|UniProtKB=Q8NFQ6 Q8NFQ6 BPIFC PTHR10504:SF17 BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED BPI FOLD-CONTAINING FAMILY C PROTEIN extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=14981|UniProtKB=P51003 P51003 PAPOLA PTHR10682:SF9 POLY A POLYMERASE POLY(A) POLYMERASE ALPHA adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;mRNA polyadenylation#GO:0006378;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=259|UniProtKB=P35318 P35318 ADM PTHR23414:SF3 ADRENOMEDULLIN, ADM PRO-ADRENOMEDULLIN peptide hormone#PC00179 HUMAN|HGNC=9901|UniProtKB=Q9BWF3 Q9BWF3 RBM4 PTHR23147:SF233 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=25545|UniProtKB=Q4KMZ1 Q4KMZ1 IQCC PTHR16049:SF8 IQ DOMAIN-CONTAINING PROTEIN C IQ DOMAIN-CONTAINING PROTEIN C HUMAN|HGNC=1310|UniProtKB=Q9Y519 Q9Y519 TMEM184B PTHR23423:SF28 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184B localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=8630|UniProtKB=P30086 P30086 PEBP1 PTHR11362:SF109 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 1 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;MAPK cascade#GO:0000165;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936 protease inhibitor#PC00191 EGF receptor signaling pathway#P00018>RKIP#P00548;FGF signaling pathway#P00021>RKIP#P00630 HUMAN|HGNC=17176|UniProtKB=Q9NRV9 Q9NRV9 HEBP1 PTHR11220:SF22 HEME-BINDING PROTEIN-RELATED HEME-BINDING PROTEIN 1 HUMAN|HGNC=29944|UniProtKB=Q9P273 Q9P273 TENM3 PTHR11219:SF65 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-3 identical protein binding#GO:0042802;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein homodimerization activity#GO:0042803;binding#GO:0005488 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;developmental process#GO:0032502;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;nervous system development#GO:0007399;cell development#GO:0048468;system development#GO:0048731;cell differentiation#GO:0030154;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=3828|UniProtKB=P25089 P25089 FPR3 PTHR24225:SF16 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 3 signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;complement binding#GO:0001848;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;immune response-regulating signaling pathway#GO:0002764;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;activation of immune response#GO:0002253;divalent inorganic cation homeostasis#GO:0072507;regulation of lipase activity#GO:0060191;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;immune response-activating signal transduction#GO:0002757;activation of phospholipase C activity#GO:0007202;regulation of immune system process#GO:0002682;regulation of hydrolase activity#GO:0051336;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;cellular cation homeostasis#GO:0030003;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;regulation of immune response#GO:0050776;positive regulation of phospholipase activity#GO:0010518;positive regulation of immune system process#GO:0002684;homeostatic process#GO:0042592;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;metal ion homeostasis#GO:0055065 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=30406|UniProtKB=P83110 P83110 HTRA3 PTHR22939:SF14 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA3 serine protease#PC00203 HUMAN|HGNC=21494|UniProtKB=Q5TF21 Q5TF21 SOGA3 PTHR15742:SF2 UNCHARACTERIZED PROTEIN SOGA3 HUMAN|HGNC=4472|UniProtKB=Q14330 Q14330 GPR18 PTHR24232:SF1 G-PROTEIN COUPLED RECEPTOR N-ARACHIDONYL GLYCINE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=21620|UniProtKB=Q7Z4U5 Q7Z4U5 C6orf201 PTHR35968:SF1 CHROMOSOME 6 C6ORF201 HOMOLOG CHROMOSOME 6 C6ORF201 HOMOLOG HUMAN|HGNC=27937|UniProtKB=Q6ZVH7 Q6ZVH7 ESPNL PTHR24153:SF0 ESPIN ESPIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament bundle organization#GO:0061572 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-motor actin binding protein#PC00165 HUMAN|HGNC=8751|UniProtKB=Q07002 Q07002 CDK18 PTHR24056:SF52 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 18 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=3084|UniProtKB=O14640 O14640 DVL1 PTHR10878:SF5 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1-RELATED protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Wnt signaling pathway#P00057>Dishevelled#P01447 HUMAN|HGNC=21081|UniProtKB=Q8NI08 Q8NI08 NCOA7 PTHR23354:SF68 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED NUCLEAR RECEPTOR COACTIVATOR 7 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;nuclear receptor transcription coactivator activity#GO:0030374;molecular function regulator#GO:0098772 cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;regulation of neuron death#GO:1901214;regulation of response to stress#GO:0080134;neuron death#GO:0070997;response to oxidative stress#GO:0006979;negative regulation of neuron death#GO:1901215;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;response to stimulus#GO:0050896;regulation of cellular response to stress#GO:0080135;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=15214|UniProtKB=Q8NH55 Q8NH55 OR52E5 PTHR26450:SF23 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52E5 transmembrane signal receptor#PC00197 HUMAN|HGNC=8653|UniProtKB=P05165 P05165 PCCA PTHR18866:SF33 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824 ligase#PC00142 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 HUMAN|HGNC=25805|UniProtKB=Q9H8S5 Q9H8S5 CCNP PTHR10177:SF257 CYCLINS CYCLIN-P cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of cyclin-dependent protein kinase activity#GO:1904029;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of protein serine/threonine kinase activity#GO:0071900;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856 kinase activator#PC00138 HUMAN|HGNC=25498|UniProtKB=Q6B0I6 Q6B0I6 KDM4D PTHR10694:SF21 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4D 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin remodeling#GO:0006338;organelle organization#GO:0006996;chromosome organization#GO:0051276 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=28093|UniProtKB=A8MTZ0 A8MTZ0 BBIP1 PTHR28596:SF1 BBSOME-INTERACTING PROTEIN 1 BBSOME-INTERACTING PROTEIN 1 localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;BBSome#GO:0034464;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=24979|UniProtKB=Q53T59 Q53T59 HS1BP3 PTHR14431:SF1 HCLS1-BINDING PROTEIN 3 HCLS1-BINDING PROTEIN 3 HUMAN|HGNC=5201|UniProtKB=O60243 O60243 HS6ST1 PTHR12812:SF1 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;heparan sulfate proteoglycan metabolic process#GO:0030201;proteoglycan biosynthetic process#GO:0030166;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=4729|UniProtKB=P20671 P20671 H2AC7 PTHR23430:SF56 HISTONE H2A HISTONE H2A TYPE 1-D heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;chromatin organization involved in negative regulation of transcription#GO:0097549;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;chromatin organization involved in regulation of transcription#GO:0034401;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;chromatin silencing#GO:0006342;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;negative regulation of gene expression, epigenetic#GO:0045814;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone#PC00118 HUMAN|HGNC=17761|UniProtKB=Q9NZC2 Q9NZC2 TREM2 PTHR11860:SF54 POLYMERIC-IMMUNOGLOBULIN RECEPTOR TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=9685|UniProtKB=P23471 P23471 PTPRZ1 PTHR19134:SF461 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ZETA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 peptidyl-tyrosine dephosphorylation#GO:0035335;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=11185|UniProtKB=Q92673 Q92673 SORL1 PTHR12106:SF20 SORTILIN RELATED SORTILIN-RELATED RECEPTOR cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;cellular protein localization#GO:0034613;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein targeting to lysosome#GO:0006622;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;protein localization to Golgi apparatus#GO:0034067;vesicle-mediated transport#GO:0016192;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=9803|UniProtKB=P60763 P60763 RAC3 PTHR24072:SF325 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168 establishment or maintenance of cell polarity#GO:0007163;regulation of anatomical structure morphogenesis#GO:0022603;regulation of organelle organization#GO:0033043;developmental process#GO:0032502;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;actin cytoskeleton organization#GO:0030036 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;neuron projection#GO:0043005;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 small GTPase#PC00208 Huntington disease#P00029>Rac#P00775;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rac#P00872;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Axon guidance mediated by semaphorins#P00007>Rac#P00340;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;VEGF signaling pathway#P00056>Rac#P01421;Ras Pathway#P04393>Rac#P04559;Axon guidance mediated by netrin#P00009>Rac#P00366;B cell activation#P00010>Rac#P00385;FGF signaling pathway#P00021>Rac#P00645;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354 HUMAN|HGNC=25671|UniProtKB=Q5TBB1 Q5TBB1 RNASEH2B PTHR13383:SF11 RIBONUCLEASE H2 SUBUNIT B RIBONUCLEASE H2 SUBUNIT B catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;cellular macromolecule catabolic process#GO:0044265;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9807|UniProtKB=O75943 O75943 RAD17 PTHR12172:SF2 CELL CYCLE CHECKPOINT PROTEIN RAD17 CELL CYCLE CHECKPOINT PROTEIN RAD17 chromatin binding#GO:0003682;binding#GO:0005488 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;mitotic DNA replication checkpoint#GO:0033314;regulation of biological process#GO:0050789;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle G2/M phase transition#GO:1902750;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle#GO:0045786;regulation of cell cycle phase transition#GO:1901987;negative regulation of cell cycle phase transition#GO:1901988;cellular metabolic process#GO:0044237;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;mitotic DNA integrity checkpoint#GO:0044774;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;G2/M transition of mitotic cell cycle#GO:0000086;response to stress#GO:0006950;DNA replication checkpoint#GO:0000076;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cellular response to stress#GO:0033554;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=14987|UniProtKB=Q8TDY4 Q8TDY4 ASAP3 PTHR45854:SF1 ASAP FAMILY MEMBER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 HUMAN|HGNC=20855|UniProtKB=Q8WTV1 Q8WTV1 THAP3 PTHR47120:SF1 THAP DOMAIN-CONTAINING PROTEIN 3 THAP DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=3179|UniProtKB=P25101 P25101 EDNRA PTHR46099:SF2 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN ENDOTHELIN-1 RECEPTOR Endothelin signaling pathway#P00019>ET-RA/B#P00580 HUMAN|HGNC=18114|UniProtKB=Q5VWX1 Q5VWX1 KHDRBS2 PTHR11208:SF34 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 2 nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA splicing factor#PC00148 HUMAN|HGNC=16793|UniProtKB=Q8TD07 Q8TD07 RAET1E PTHR16675:SF64 MHC CLASS I-RELATED RETINOIC ACID EARLY TRANSCRIPT 1E response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=1743|UniProtKB=Q99459 Q99459 CDC5L PTHR45885:SF1 CELL DIVISION CYCLE 5-LIKE PROTEIN CELL DIVISION CYCLE 5-LIKE PROTEIN cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;Prp19 complex#GO:0000974;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=53905|UniProtKB=A0A2R8Y4Y8 A0A2R8Y4Y8 OOSP4B PTHR14380:SF9 PLACENTA-SPECIFIC PROTEIN 1 OOCYTE-SECRETED PROTEIN 4B HUMAN|HGNC=17307|UniProtKB=O14981 O14981 BTAF1 PTHR36498:SF1 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 HUMAN|HGNC=2420|UniProtKB=O95825 O95825 CRYZL1 PTHR44461:SF1 QUINONE OXIDOREDUCTASE-LIKE PROTEIN 1 QUINONE OXIDOREDUCTASE-LIKE PROTEIN 1 oxidoreductase#PC00176 HUMAN|HGNC=8592|UniProtKB=O75914 O75914 PAK3 PTHR48015:SF30 SERINE/THREONINE-PROTEIN KINASE TAO SERINE/THREONINE-PROTEIN KINASE PAK 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;axonogenesis#GO:0007409;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;regulation of neuron differentiation#GO:0045664;primary metabolic process#GO:0044238;regulation of neuron projection development#GO:0010975;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of axonogenesis#GO:0050770;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of cell morphogenesis involved in differentiation#GO:0010769;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell development#GO:0060284;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 T cell activation#P00053>PAK#P01319;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517;Ras Pathway#P04393>PAK#P04553;Angiogenesis#P00005>PAK#P00249 HUMAN|HGNC=16356|UniProtKB=Q495M9 Q495M9 USH1G PTHR24161:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED USHER SYNDROME TYPE-1G PROTEIN HUMAN|HGNC=19169|UniProtKB=O95772 O95772 STARD3NL PTHR46121:SF1 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STARD3 N-TERMINAL-LIKE PROTEIN HUMAN|HGNC=25361|UniProtKB=Q8N264 Q8N264 ARHGAP24 PTHR15228:SF19 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 24 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 cellular component biogenesis#GO:0044085;cell projection organization#GO:0030030;Ras protein signal transduction#GO:0007265;regulation of cellular component organization#GO:0051128;regulation of intracellular signal transduction#GO:1902531;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular component biogenesis#GO:0044087;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;negative regulation of cellular component organization#GO:0051129;negative regulation of cell communication#GO:0010648;cellular component assembly#GO:0022607;regulation of GTPase activity#GO:0043087;negative regulation of signaling#GO:0023057;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;response to wounding#GO:0009611;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;negative regulation of signal transduction#GO:0009968;plasma membrane bounded cell projection assembly#GO:0120031;regulation of Ras protein signal transduction#GO:0046578;locomotion#GO:0040011;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;epithelium development#GO:0060429;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;negative regulation of Ras protein signal transduction#GO:0046580;wound healing#GO:0042060;regulation of catalytic activity#GO:0050790;negative regulation of small GTPase mediated signal transduction#GO:0051058;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;positive regulation of GTPase activity#GO:0043547;positive regulation of catalytic activity#GO:0043085;cell motility#GO:0048870;cellular process#GO:0009987;tissue development#GO:0009888;cell projection assembly#GO:0030031;localization#GO:0051179;response to stimulus#GO:0050896;regulation of cell projection assembly#GO:0060491;biological regulation#GO:0065007;tissue morphogenesis#GO:0048729;morphogenesis of an epithelium#GO:0002009;cell migration#GO:0016477 cell junction#GO:0030054;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;focal adhesion#GO:0005925 HUMAN|HGNC=13760|UniProtKB=Q96F07 Q96F07 CYFIP2 PTHR12195:SF3 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;RNA cap binding#GO:0000339;binding#GO:0005488;organic cyclic compound binding#GO:0097159 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell morphogenesis#GO:0000902;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 HUMAN|HGNC=13708|UniProtKB=O15218 O15218 GPR182 PTHR24226:SF0 G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1 G-PROTEIN COUPLED RECEPTOR 182 G-protein coupled receptor#PC00021 HUMAN|HGNC=28714|UniProtKB=Q6UX72 Q6UX72 B3GNT9 PTHR11214:SF91 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 9 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nitrogen compound metabolic process#GO:0006807;aminoglycan biosynthetic process#GO:0006023;aminoglycan metabolic process#GO:0006022;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;cellular carbohydrate biosynthetic process#GO:0034637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;cellular polysaccharide biosynthetic process#GO:0033692;cellular polysaccharide metabolic process#GO:0044264;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=24094|UniProtKB=Q8IWT0 Q8IWT0 ZBTB8OS PTHR12682:SF12 ARCHEASE PROTEIN ARCHEASE cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=976|UniProtKB=P54687 P54687 BCAT1 PTHR11825:SF70 SUBGROUP IIII AMINOTRANSFERASE BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE, CYTOSOLIC transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;branched-chain amino acid biosynthetic process#GO:0009082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 transaminase#PC00216 Alanine biosynthesis#P02724>Branched chain amino acid aminotransferase#P02815;Leucine biosynthesis#P02749>Branched chain amino acid aminotransferase#P03000;Valine biosynthesis#P02785>Branched chain amino acid aminotransferase#P03215;Isoleucine biosynthesis#P02748>Branched chain amino acid aminotransferase#P02994 HUMAN|HGNC=28801|UniProtKB=Q9H3H3 Q9H3H3 C11orf68 PTHR31977:SF1 UPF0696 PROTEIN C11ORF68 UPF0696 PROTEIN C11ORF68 HUMAN|HGNC=18555|UniProtKB=Q9BX93 Q9BX93 PLA2G12B PTHR12824:SF2 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GROUP XIIB SECRETORY PHOSPHOLIPASE A2-LIKE PROTEIN biological regulation#GO:0065007;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;triglyceride homeostasis#GO:0070328;chemical homeostasis#GO:0048878;regulation of biological quality#GO:0065008;cholesterol homeostasis#GO:0042632 phospholipase#PC00186 HUMAN|HGNC=17066|UniProtKB=Q9UKV3 Q9UKV3 ACIN1 PTHR46589:SF1 APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS HUMAN|HGNC=22408|UniProtKB=Q7Z3C6 Q7Z3C6 ATG9A PTHR13038:SF13 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9A cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;autophagy of mitochondrion#GO:0000422;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle disassembly#GO:1903008;protein localization#GO:0008104;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;autophagy of nucleus#GO:0044804;autophagy#GO:0006914 cytoplasm#GO:0005737;phagophore assembly site#GO:0000407;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;autophagosome#GO:0005776;intracellular organelle#GO:0043229 HUMAN|HGNC=25652|UniProtKB=Q9H089 Q9H089 LSG1 PTHR45709:SF2 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED LARGE SUBUNIT GTPASE 1 HOMOLOG hydrolase activity#GO:0016787;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=25073|UniProtKB=Q96E39 Q96E39 RBMXL1 PTHR48034:SF20 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED RNA BINDING MOTIF PROTEIN, X-LINKED-LIKE-1 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;positive regulation of RNA metabolic process#GO:0051254;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=37242|UniProtKB=Q86WV5 Q86WV5 TEN1 PTHR33905:SF1 CST COMPLEX SUBUNIT TEN1 CST COMPLEX SUBUNIT TEN1 nucleic acid binding#GO:0003676;RNA-directed DNA polymerase activity#GO:0003964;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme inhibitor activity#GO:0004857;telomerase activity#GO:0003720;enzyme regulator activity#GO:0030234;sequence-specific DNA binding#GO:0043565;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 telomere maintenance via telomere lengthening#GO:0010833;cellular component biogenesis#GO:0044085;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;telomere-telomerase complex assembly#GO:1905324;regulation of biological process#GO:0050789;regulation of telomere maintenance via telomerase#GO:0032210;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;RNA-dependent DNA biosynthetic process#GO:0006278;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;telomere organization#GO:0032200;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;negative regulation of organelle organization#GO:0010639;regulation of macromolecule biosynthetic process#GO:0010556;telomere maintenance via telomerase#GO:0007004;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;homeostatic process#GO:0042592;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of telomere maintenance via telomere lengthening#GO:1904356;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;nuclear telomere cap complex#GO:0000783;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781;protein-DNA complex#GO:0032993;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28981|UniProtKB=Q5TAX3 Q5TAX3 TUT4 PTHR12271:SF49 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE 4 adenylyltransferase activity#GO:0070566;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;uridylyltransferase activity#GO:0070569;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA 3'-end processing#GO:0031124;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of gene expression#GO:0010468;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;gene silencing by miRNA#GO:0035195;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;mRNA polyadenylation#GO:0006378;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;gene silencing by RNA#GO:0031047;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;production of miRNAs involved in gene silencing by miRNA#GO:0035196;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;posttranscriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;mRNA processing#GO:0006397;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 HUMAN|HGNC=24820|UniProtKB=Q15884 Q15884 FAM189A2 PTHR17615:SF8 PROTEIN FAM189A PROTEIN FAM189A2 HUMAN|HGNC=29176|UniProtKB=Q684P5 Q684P5 RAP1GAP2 PTHR15711:SF17 RAP GTPASE-ACTIVATING PROTEIN RAP1 GTPASE-ACTIVATING PROTEIN 2 GTPase-activating protein#PC00257 HUMAN|HGNC=18563|UniProtKB=Q9HBJ7 Q9HBJ7 USP29 PTHR24006:SF711 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 26-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=15252|UniProtKB=Q8NH89 Q8NH89 OR5AK3P PTHR48018:SF90 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5AK3-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=2709|UniProtKB=P40126 P40126 DCT PTHR11474:SF4 TYROSINASE FAMILY MEMBER L-DOPACHROME TAUTOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 secondary metabolic process#GO:0019748;pigmentation#GO:0043473;brain development#GO:0007420;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;nervous system development#GO:0007399;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;central nervous system development#GO:0007417;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;cellular developmental process#GO:0048869;oxoacid metabolic process#GO:0043436;regulation of multicellular organismal process#GO:0051239;cellular metabolic process#GO:0044237;pigment metabolic process#GO:0042440;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;forebrain development#GO:0030900;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;cellular amino acid metabolic process#GO:0006520;positive regulation of multicellular organismal process#GO:0051240;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;head development#GO:0060322;neurogenesis#GO:0022008;cell division#GO:0051301;tyrosine metabolic process#GO:0006570;animal organ development#GO:0048513;developmental process#GO:0032502;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;system development#GO:0048731;developmental pigmentation#GO:0048066;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid family metabolic process#GO:0009072;pigment biosynthetic process#GO:0046148;metabolic process#GO:0008152;regulation of cell population proliferation#GO:0042127;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of nervous system development#GO:0051962;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;cell development#GO:0048468;secondary metabolite biosynthetic process#GO:0044550;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;generation of neurons#GO:0048699;carboxylic acid metabolic process#GO:0019752 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cellular anatomical entity#GO:0110165;organelle#GO:0043226;melanosome#GO:0042470;vesicle#GO:0031982;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=3465|UniProtKB=P10768 P10768 ESD PTHR10061:SF0 S-FORMYLGLUTATHIONE HYDROLASE S-FORMYLGLUTATHIONE HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 serine protease#PC00203 HUMAN|HGNC=6453|UniProtKB=Q92764 Q92764 KRT35 PTHR23239:SF193 INTERMEDIATE FILAMENT KERATIN, TYPE I CUTICULAR HA5 HUMAN|HGNC=21226|UniProtKB=Q9ULH4 Q9ULH4 LRFN2 PTHR45842:SF6 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 2 intrinsic component of postsynaptic membrane#GO:0098936;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;integral component of synaptic membrane#GO:0099699;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;synaptic membrane#GO:0097060;integral component of postsynaptic specialization membrane#GO:0099060;integral component of postsynaptic membrane#GO:0099055;asymmetric synapse#GO:0032279;cell surface#GO:0009986;intrinsic component of membrane#GO:0031224;intrinsic component of synaptic membrane#GO:0099240;integral component of postsynaptic density membrane#GO:0099061;postsynaptic density membrane#GO:0098839;integral component of plasma membrane#GO:0005887;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;intrinsic component of postsynaptic specialization membrane#GO:0098948;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 HUMAN|HGNC=25949|UniProtKB=Q9NXT0 Q9NXT0 ZNF586 PTHR24377:SF708 IP01015P-RELATED ZINC FINGER PROTEIN 586 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12238|UniProtKB=A0A1B0GX95 A0A1B0GX95 TRBV7-4 PTHR23268:SF78 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 7-4-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=16848|UniProtKB=Q6UXZ3 Q6UXZ3 CD300LD PTHR11860:SF101 POLYMERIC-IMMUNOGLOBULIN RECEPTOR CMRF35-LIKE MOLECULE 5 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=29147|UniProtKB=Q9Y2D9 Q9Y2D9 ZNF652 PTHR24394:SF21 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 652 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=5817|UniProtKB=P01619 P01619 IGKV3-20 PTHR23267:SF472 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 3-20-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=6174|UniProtKB=Q9Y287 Q9Y287 ITM2B PTHR10962:SF4 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2B amyloid-beta binding#GO:0001540;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218 glycoprotein biosynthetic process#GO:0009101;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;carbohydrate derivative metabolic process#GO:1901135;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;carbohydrate derivative biosynthetic process#GO:1901137;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=33911|UniProtKB=Q6P5S7 Q6P5S7 RNASEK PTHR31733:SF1 RIBONUCLEASE KAPPA RIBONUCLEASE KAPPA catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;endoribonuclease activity#GO:0004521;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;ribonuclease activity#GO:0004540 HUMAN|HGNC=12635|UniProtKB=P46939 P46939 UTRN PTHR11915:SF439 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN UTROPHIN HUMAN|HGNC=10435|UniProtKB=Q9UK32 Q9UK32 RPS6KA6 PTHR24351:SF98 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE ALPHA-6 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 Ras Pathway#P04393>p90RSK#P04541;Interleukin signaling pathway#P00036>p90RSK#P00964;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;PDGF signaling pathway#P00047>p90RSK#P01142 HUMAN|HGNC=12790|UniProtKB=O00258 O00258 GET1 PTHR42650:SF1 TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1 cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;macromolecule localization#GO:0033036;membrane organization#GO:0061024;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to membrane#GO:0090150;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein localization to organelle#GO:0033365;protein insertion into membrane#GO:0051205 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=24563|UniProtKB=Q9Y421 Q9Y421 FAM32A PTHR13282:SF10 UNCHARACTERIZED PROTEIN FAM32A intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26479|UniProtKB=Q96MU6 Q96MU6 ZNF778 PTHR24381:SF153 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 778 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=2698|UniProtKB=P11182 P11182 DBT PTHR43178:SF5 DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 acetyltransferase#PC00038 HUMAN|HGNC=23503|UniProtKB=Q9H5Y7 Q9H5Y7 SLITRK6 PTHR45773:SF1 SLIT AND NTRK-LIKE PROTEIN 4-RELATED SLIT AND NTRK-LIKE PROTEIN 6 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cell projection organization#GO:0030030;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;system development#GO:0048731;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron differentiation#GO:0030182;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;generation of neurons#GO:0048699;cell part morphogenesis#GO:0032990 HUMAN|HGNC=9220|UniProtKB=Q15319 Q15319 POU4F3 PTHR11636:SF43 POU DOMAIN POU DOMAIN, CLASS 4, TRANSCRIPTION FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=19949|UniProtKB=O75817 O75817 POP7 PTHR15314:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P20 RIBONUCLEASE P PROTEIN SUBUNIT P20 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on a tRNA#GO:0140101 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 endoribonuclease#PC00094 HUMAN|HGNC=33879|UniProtKB=Q5SXM8 Q5SXM8 DNLZ PTHR20922:SF13 UNCHARACTERIZED DNL-TYPE ZINC FINGER PROTEIN protein binding#GO:0005515;chaperone binding#GO:0051087;binding#GO:0005488 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein transmembrane import into intracellular organelle#GO:0044743;protein stabilization#GO:0050821;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;protein targeting to mitochondrion#GO:0006626;protein localization to organelle#GO:0033365;mitochondrion organization#GO:0007005;protein import#GO:0017038;mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;protein targeting#GO:0006605;regulation of protein stability#GO:0031647;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization to mitochondrion#GO:0070585;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;protein import into mitochondrial matrix#GO:0030150;cellular macromolecule localization#GO:0070727;establishment of protein localization to mitochondrion#GO:0072655;organelle organization#GO:0006996;protein folding#GO:0006457;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=40045|UniProtKB=Q6UWS5 Q6UWS5 PET117 PTHR28163:SF1 PROTEIN PET117 HOMOLOG, MITOCHONDRIAL PROTEIN PET117 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;organelle organization#GO:0006996;cytochrome complex assembly#GO:0017004;protein-containing complex assembly#GO:0065003;mitochondrial cytochrome c oxidase assembly#GO:0033617;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=576|UniProtKB=O14727 O14727 APAF1 PTHR22845:SF6 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 p53 pathway#P00059>Apaf#G04703;Apoptosis signaling pathway#P00006>Apaf-1#P00301;FAS signaling pathway#P00020>Apaf1#P00597;Huntington disease#P00029>Apaf-1#P00768 HUMAN|HGNC=7712|UniProtKB=O43920 O43920 NDUFS5 PTHR15224:SF1 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 dehydrogenase#PC00092 HUMAN|HGNC=1581|UniProtKB=P24863 P24863 CCNC PTHR10026:SF7 CYCLIN CYCLIN-C cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;cyclin binding#GO:0030332;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 kinase activator#PC00138 HUMAN|HGNC=8090|UniProtKB=Q15646 Q15646 OASL PTHR11258:SF16 2-5 OLIGOADENYLATE SYNTHETASE 2'-5'-OLIGOADENYLATE SYNTHASE-LIKE PROTEIN adenylyltransferase activity#GO:0070566;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;heterocyclic compound binding#GO:1901363;double-stranded RNA binding#GO:0003725 response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;RNA phosphodiester bond hydrolysis#GO:0090501;regulation of catalytic activity#GO:0050790;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;defense response to other organism#GO:0098542;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229 nucleotidyltransferase#PC00174 HUMAN|HGNC=24801|UniProtKB=A4FU69 A4FU69 EFCAB5 PTHR46788:SF1 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 5 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 5 calmodulin-related#PC00061 HUMAN|HGNC=18011|UniProtKB=Q96G61 Q96G61 NUDT11 PTHR12629:SF35 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 3-BETA pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleotide diphosphatase activity#GO:0004551;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organophosphate catabolic process#GO:0046434;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphatase#PC00181 HUMAN|HGNC=8490|UniProtKB=O43929 O43929 ORC4 PTHR12087:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;DNA biosynthetic process#GO:0071897;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 origin recognition complex#GO:0000808;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;nuclear origin of replication recognition complex#GO:0005664;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 replication origin binding protein#PC00199 HUMAN|HGNC=6307|UniProtKB=P35968 P35968 KDR PTHR24416:SF45 TYROSINE-PROTEIN KINASE RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 positive regulation of cellular metabolic process#GO:0031325;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of vasculature development#GO:1901342;regulation of molecular function#GO:0065009;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;blood vessel morphogenesis#GO:0048514;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;tube development#GO:0035295;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501;endothelial cell differentiation#GO:0045446;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;positive regulation of angiogenesis#GO:0045766;regulation of anatomical structure morphogenesis#GO:0022603;epithelium development#GO:0060429;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;regulation of angiogenesis#GO:0045765;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;signaling#GO:0023052;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell motility#GO:0048870;epithelial cell differentiation#GO:0030855;cellular process#GO:0009987;tissue development#GO:0009888;positive regulation of developmental process#GO:0051094;anatomical structure formation involved in morphogenesis#GO:0048646;localization#GO:0051179;response to stimulus#GO:0050896;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;cell migration#GO:0016477;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>VEGFR-2#P00222;VEGF signaling pathway#P00056>VEGFR-2#P01403 HUMAN|HGNC=14584|UniProtKB=Q9H269 Q9H269 VPS16 PTHR12811:SF0 VACUOLAR PROTEIN SORTING VPS16 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;protein-containing complex assembly#GO:0065003;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;regulation of transport#GO:0051049;regulation of protein-containing complex assembly#GO:0043254;establishment of localization#GO:0051234;regulation of cellular component biogenesis#GO:0044087;vesicle organization#GO:0016050;protein-containing complex subunit organization#GO:0043933;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;regulation of cellular process#GO:0050794;vacuole fusion, non-autophagic#GO:0042144;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=24116|UniProtKB=Q8TDP1 Q8TDP1 RNASEH2C PTHR47063:SF1 RIBONUCLEASE H2 SUBUNIT C RIBONUCLEASE H2 SUBUNIT C cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;heterocycle catabolic process#GO:0046700;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;aromatic compound catabolic process#GO:0019439;nitrogen compound metabolic process#GO:0006807;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;nucleobase-containing compound catabolic process#GO:0034655;organic substance catabolic process#GO:1901575;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=28268|UniProtKB=Q8N7N1 Q8N7N1 FAM86B1 PTHR14614:SF128 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN N-METHYLTRANSFERASE FAM86B1-RELATED HUMAN|HGNC=9456|UniProtKB=P07225 P07225 PROS1 PTHR24040:SF0 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN VITAMIN K-DEPENDENT PROTEIN S extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 Blood coagulation#P00011>PS#P00412 HUMAN|HGNC=28460|UniProtKB=Q8N3J3 Q8N3J3 HROB PTHR14523:SF1 UNCHARACTERIZED PROTEIN C17ORF53 HOMOLOG HOMOLOGOUS RECOMBINATION OB-FOLD PROTEIN HUMAN|Ensembl=ENSG00000283288|UniProtKB=A0A1B0GW64 A0A1B0GW64 SMIM33 PTHR37873:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 33 SMALL INTEGRAL MEMBRANE PROTEIN 33 HUMAN|HGNC=23074|UniProtKB=Q9NX70 Q9NX70 MED29 PTHR28314:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 general transcription factor#PC00259 HUMAN|HGNC=27611|UniProtKB=Q6ZN19 Q6ZN19 ZNF841 PTHR24376:SF128 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 836-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=11980|UniProtKB=Q14106 Q14106 TOB2 PTHR17537:SF3 TRANSDUCER OF ERBB2 TOB PROTEIN TOB2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription corepressor activity#GO:0003714 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=24605|UniProtKB=Q96K83 Q96K83 ZNF521 PTHR24376:SF84 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 521 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4851|UniProtKB=P42858 P42858 HTT PTHR10170:SF10 HUNTINGTON DISEASE PROTEIN HUNTINGTIN cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 Huntington disease#P00029>Htt#P00766;Huntington disease#P00029>PolyQ Htt#P00800;Huntington disease#P00029>PolyQ HTT#G01532;Huntington disease#P00029>Truncated Htt#P00761;Huntington disease#P00029>HTT#G01530 HUMAN|HGNC=26202|UniProtKB=Q6IN84 Q6IN84 MRM1 PTHR46103:SF1 RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL RNA methyltransferase#PC00033 HUMAN|HGNC=24584|UniProtKB=Q5RIA9 Q5RIA9 CBWD5 PTHR13748:SF31 COBW-RELATED COBW DOMAIN-CONTAINING PROTEIN 1-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=12496|UniProtKB=Q05086 Q05086 UBE3A PTHR45622:SF40 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HECTD2-RELATED ubiquitin-protein ligase#PC00234 EGF receptor signaling pathway#P00018>RKIP#P00548;Ubiquitin proteasome pathway#P00060>E3#P01490 HUMAN|HGNC=16188|UniProtKB=Q9BQ89 Q9BQ89 FAM110A PTHR14758:SF4 AGAP005440-PA PROTEIN FAM110A HUMAN|HGNC=9337|UniProtKB=P04280 P04280 PRB1 PTHR23203:SF16 PROLINE-RICH PROTEIN BASIC SALIVARY PROLINE-RICH PROTEIN 1-RELATED antimicrobial response protein#PC00051 HUMAN|HGNC=28926|UniProtKB=Q8N1N4 Q8N1N4 KRT78 PTHR45616:SF18 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 78 HUMAN|HGNC=5009|UniProtKB=P52926 P52926 HMGA2 PTHR23341:SF4 HIGH MOBILITY GROUP PROTEINS HMG-A AND C HIGH MOBILITY GROUP PROTEIN HMGI-C transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 endodeoxyribonuclease#PC00093 HUMAN|HGNC=9032|UniProtKB=Q5R387 Q5R387 PLA2G2C PTHR11716:SF5 PHOSPHOLIPASE A2 FAMILY MEMBER INACTIVE GROUP IIC SECRETORY PHOSPHOLIPASE A2-RELATED cation binding#GO:0043169;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipase activity#GO:0004620;anion binding#GO:0043168;phospholipid binding#GO:0005543 lipid metabolic process#GO:0006629;negative regulation of biological process#GO:0048519;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;phospholipid metabolic process#GO:0006644;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;phosphorus metabolic process#GO:0006793;leukocyte cell-cell adhesion#GO:0007159;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;T cell proliferation#GO:0042098;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;regulation of immune system process#GO:0002682;negative regulation of cell population proliferation#GO:0008285;regulation of cell adhesion#GO:0030155;negative regulation of cellular process#GO:0048523;regulation of lymphocyte activation#GO:0051249;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;metabolic process#GO:0008152;negative regulation of T cell proliferation#GO:0042130;lymphocyte activation#GO:0046649;negative regulation of T cell activation#GO:0050868;regulation of cell population proliferation#GO:0042127;cellular metabolic process#GO:0044237;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cell adhesion#GO:0007155;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;negative regulation of leukocyte activation#GO:0002695;primary metabolic process#GO:0044238;regulation of T cell proliferation#GO:0042129;negative regulation of cell adhesion#GO:0007162;cell activation#GO:0001775;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;negative regulation of immune system process#GO:0002683;organophosphate metabolic process#GO:0019637;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;cellular lipid metabolic process#GO:0044255 phospholipase#PC00186 HUMAN|HGNC=15100|UniProtKB=Q8NGS8 Q8NGS8 OR13C5 PTHR26453:SF121 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C5 transmembrane signal receptor#PC00197 HUMAN|HGNC=13589|UniProtKB=Q9UK96 Q9UK96 FBXO10 PTHR22990:SF15 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 10 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=28297|UniProtKB=Q8WV15 Q8WV15 TMEM255B PTHR33721:SF3 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 255B HUMAN|HGNC=29999|UniProtKB=Q86X02 Q86X02 CDR2L PTHR19232:SF10 CENTROCORTIN FAMILY MEMBER CEREBELLAR DEGENERATION-RELATED PROTEIN 2-LIKE HUMAN|HGNC=6019|UniProtKB=P08887 P08887 IL6R PTHR23036:SF98 CYTOKINE RECEPTOR INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA signaling receptor activity#GO:0038023;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;growth factor binding#GO:0019838;protein binding#GO:0005515;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;positive regulation of receptor signaling pathway via STAT#GO:1904894;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;tyrosine phosphorylation of STAT protein#GO:0007260;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;regulation of receptor signaling pathway via STAT#GO:1904892;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;peptidyl-tyrosine modification#GO:0018212;positive regulation of protein kinase activity#GO:0045860;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=5057|UniProtKB=O43763 O43763 TLX2 PTHR45921:SF3 IP01054P T-CELL LEUKEMIA HOMEOBOX PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=32003|UniProtKB=Q5VYP0 Q5VYP0 SPATA31A3 PTHR21859:SF55 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31A1-RELATED HUMAN|HGNC=11292|UniProtKB=P30626 P30626 SRI PTHR10891:SF918 EF-HAND CALCIUM-BINDING DOMAIN CONTAINING PROTEIN SORCIN calmodulin-related#PC00061 HUMAN|HGNC=2069|UniProtKB=P49760 P49760 CLK2 PTHR45646:SF6 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED DUAL SPECIFICITY PROTEIN KINASE CLK2 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=15315|UniProtKB=Q8NH50 Q8NH50 OR8K5 PTHR48018:SF13 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8K5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=27110|UniProtKB=Q8N6D5 Q8N6D5 ANKRD29 PTHR24120:SF3 GH07239P ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 29 HUMAN|HGNC=7977|UniProtKB=P10588 P10588 NR2F6 PTHR24083:SF44 NUCLEAR HORMONE RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 2 GROUP F MEMBER 6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=29091|UniProtKB=O75143 O75143 ATG13 PTHR13430:SF4 UNCHARACTERIZED AUTOPHAGY-RELATED PROTEIN 13 protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;kinase activity#GO:0016301;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase binding#GO:0019900;protein kinase activity#GO:0004672;transferase activity#GO:0016740;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macroautophagy#GO:0016236;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;autophagy of mitochondrion#GO:0000422;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;vacuole organization#GO:0007033;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;autophagy#GO:0006914;piecemeal microautophagy of the nucleus#GO:0034727;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;positive regulation of molecular function#GO:0044093;nucleus organization#GO:0006997;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;process utilizing autophagic mechanism#GO:0061919;positive regulation of transferase activity#GO:0051347;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;lysosomal microautophagy#GO:0016237;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;organelle disassembly#GO:1903008;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;organelle assembly#GO:0070925;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;autophagy of nucleus#GO:0044804;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;phagophore assembly site#GO:0000407;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;cytosol#GO:0005829;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 HUMAN|HGNC=32400|UniProtKB=Q30KP9 Q30KP9 DEFB135 PTHR15001:SF10 BETA-DEFENSIN 123-RELATED BETA-DEFENSIN 135 antimicrobial response protein#PC00051 HUMAN|HGNC=17923|UniProtKB=Q9NZI5 Q9NZI5 GRHL1 PTHR11037:SF16 TRANSCRIPTION FACTOR CP2 GRAINYHEAD-LIKE PROTEIN 1 HOMOLOG DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=16500|UniProtKB=Q9UN19 Q9UN19 DAPP1 PTHR14336:SF15 TANDEM PH DOMAIN CONTAINING PROTEIN DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE HUMAN|HGNC=6922|UniProtKB=P11226 P11226 MBL2 PTHR24020:SF70 COLLAGEN ALPHA MANNOSE-BINDING PROTEIN C extracellular matrix structural protein#PC00103 HUMAN|HGNC=4273|UniProtKB=Q14161 Q14161 GIT2 PTHR46097:SF4 G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP ARF GTPASE-ACTIVATING PROTEIN GIT2 HUMAN|HGNC=5434|UniProtKB=P01574 P01574 IFNB1 PTHR11691:SF72 TYPE I INTERFERON INTERFERON BETA receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 Toll receptor signaling pathway#P00054>Gene trancription#G01550 HUMAN|HGNC=25898|UniProtKB=Q96CM3 Q96CM3 RPUSD4 PTHR21600:SF51 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE RPUSD4 RNA processing factor#PC00147 HUMAN|HGNC=23056|UniProtKB=Q92685 Q92685 ALG3 PTHR12646:SF0 NOT56 - RELATED DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=6370|UniProtKB=Q9UKQ9 Q9UKQ9 KLK9 PTHR24271:SF57 KALLIKREIN-RELATED KALLIKREIN-9 intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=17356|UniProtKB=Q8IUX4 Q8IUX4 APOBEC3F PTHR13857:SF45 MRNA EDITING ENZYME DNA DC-DU-EDITING ENZYME APOBEC-3F RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;heterocyclic compound binding#GO:1901363 response to external biotic stimulus#GO:0043207;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;RNA phosphodiester bond hydrolysis#GO:0090501;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;defense response to virus#GO:0051607;demethylation#GO:0070988;defense response#GO:0006952;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;transposition#GO:0032196;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;RNA-dependent DNA biosynthetic process#GO:0006278;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;nucleic acid phosphodiester bond hydrolysis#GO:0090305;DNA biosynthetic process#GO:0071897;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 RNA processing factor#PC00147 HUMAN|HGNC=14693|UniProtKB=Q8NGX5 Q8NGX5 OR10K1 PTHR26451:SF476 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10K1 HUMAN|HGNC=26488|UniProtKB=A6PVL3 A6PVL3 KNCN PTHR38497:SF1 KINOCILIN KINOCILIN HUMAN|HGNC=598|UniProtKB=Q06481 Q06481 APLP2 PTHR23103:SF14 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID-LIKE PROTEIN 2 protease inhibitor#PC00191 HUMAN|HGNC=10665|UniProtKB=Q9BVJ6 Q9BVJ6 UTP14A PTHR14150:SF14 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 HOMOLOG A membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 HUMAN|HGNC=489|UniProtKB=O95841 O95841 ANGPTL1 PTHR19143:SF25 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 1 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=7155|UniProtKB=P03956 P03956 MMP1 PTHR10201:SF151 MATRIX METALLOPROTEINASE INTERSTITIAL COLLAGENASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Plasminogen activating cascade#P00050>pro-MMP-1#P01263;Plasminogen activating cascade#P00050>MMP-1#P01252;Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=6294|UniProtKB=P51787 P51787 KCNQ1 PTHR11537:SF274 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;calmodulin binding#GO:0005516;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=30085|UniProtKB=Q9H7M9 Q9H7M9 VSIR PTHR44819:SF1 V-TYPE IMMUNOGLOBULIN DOMAIN-CONTAINING SUPPRESSOR OF T-CELL ACTIVATION V-TYPE IMMUNOGLOBULIN DOMAIN-CONTAINING SUPPRESSOR OF T-CELL ACTIVATION immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=14342|UniProtKB=Q9BXJ2 Q9BXJ2 C1QTNF7 PTHR15427:SF24 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 7 HUMAN|HGNC=24048|UniProtKB=Q8N6S5 Q8N6S5 ARL6IP6 PTHR28640:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 6 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 6 HUMAN|HGNC=8218|UniProtKB=Q8NGR2 Q8NGR2 OR1L6 PTHR48001:SF106 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1L6 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=10044|UniProtKB=P07998 P07998 RNASE1 PTHR11437:SF24 RIBONUCLEASE RIBONUCLEASE PANCREATIC ribonuclease activity#GO:0004540;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;RNA phosphodiester bond hydrolysis#GO:0090501;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=24451|UniProtKB=Q8IZD4 Q8IZD4 DCP1B PTHR16290:SF5 TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 MRNA-DECAPPING ENZYME 1B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729;enzyme regulator activity#GO:0030234 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;deadenylation-dependent decapping of nuclear-transcribed mRNA#GO:0000290;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 mRNA capping factor#PC00145 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 HUMAN|HGNC=7688|UniProtKB=Q16718 Q16718 NDUFA5 PTHR12653:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;electron transport chain#GO:0022900;cellular metabolic process#GO:0044237;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;mitochondrial respirasome#GO:0005746;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=24303|UniProtKB=Q8NDT2 Q8NDT2 RBM15B PTHR23189:SF40 RNA RECOGNITION MOTIF-CONTAINING RNA-BINDING PROTEIN 15B-RELATED nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=26470|UniProtKB=Q8IW00 Q8IW00 VSTM4 PTHR12207:SF8 V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=40375|UniProtKB=H3BPM6 H3BPM6 MKRN2OS PTHR33963:SF2 MKRN2 OPPOSITE STRAND PROTEIN MKRN2 OPPOSITE STRAND PROTEIN HUMAN|HGNC=24143|UniProtKB=Q969K7 Q969K7 TMEM54 PTHR31258:SF2 KERATINOCYTE-ASSOCIATED PROTEIN 3 TRANSMEMBRANE PROTEIN 54 HUMAN|HGNC=51|UniProtKB=P33527 P33527 ABCC1 PTHR24223:SF241 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 xenobiotic transmembrane transporter activity#GO:0042910;catalytic activity#GO:0003824;oligopeptide transmembrane transporter activity#GO:0035673;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;hydrolase activity#GO:0016787;amide transmembrane transporter activity#GO:0042887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;peptide transmembrane transporter activity#GO:1904680;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=1030|UniProtKB=P30411 P30411 BDKRB2 PTHR24228:SF25 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR B2 BRADYKININ RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=29282|UniProtKB=Q9P270 Q9P270 SLAIN2 PTHR22406:SF4 UNCHARACTERIZED SLAIN MOTIF-CONTAINING PROTEIN 2 HUMAN|HGNC=18064|UniProtKB=Q9H2S5 Q9H2S5 RNF39 PTHR24103:SF646 E3 UBIQUITIN-PROTEIN LIGASE TRIM RING FINGER PROTEIN 39 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=4451|UniProtKB=P51654 P51654 GPC3 PTHR10822:SF4 GLYPICAN GLYPICAN-3 cellular localization#GO:0051641;signal transduction#GO:0007165;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of localization#GO:0032879;positive regulation of Wnt signaling pathway#GO:0030177;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;regulation of protein localization#GO:0032880;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;protein localization to membrane#GO:0072657;regulation of protein localization to membrane#GO:1905475;localization of cell#GO:0051674;cell communication#GO:0007154;cell motility#GO:0048870;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;regulation of canonical Wnt signaling pathway#GO:0060828;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;response to stimulus#GO:0050896;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011 cell surface#GO:0009986;anchored component of plasma membrane#GO:0046658;intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;anchored component of membrane#GO:0031225;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=19903|UniProtKB=Q9NQL2 Q9NQL2 RRAGD PTHR11259:SF5 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN D pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 signal transduction#GO:0007165;regulation of catabolic process#GO:0009894;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to starvation#GO:0009267;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;regulation of autophagy#GO:0010506;cellular metabolic process#GO:0044237;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;response to nutrient levels#GO:0031667;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to nutrient levels#GO:0031669;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;response to starvation#GO:0042594;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;cellular response to stress#GO:0033554;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;nucleus#GO:0005634;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=11351|UniProtKB=Q9NRC1 Q9NRC1 ST7 PTHR12745:SF10 SUPPRESSION OF TUMORIGENICITY 7 SUPPRESSOR OF TUMORIGENICITY 7 PROTEIN HUMAN|HGNC=14585|UniProtKB=Q96NX5 Q96NX5 CAMK1G PTHR24347:SF116 SERINE/THREONINE-PROTEIN KINASE CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=23194|UniProtKB=Q96EK4 Q96EK4 THAP11 PTHR22794:SF2 THAP DOMAIN PROTEIN 11 THAP DOMAIN-CONTAINING PROTEIN 11 HUMAN|HGNC=28155|UniProtKB=Q9H469 Q9H469 FBXL15 PTHR13318:SF179 UNCHARACTERIZED F-BOX/LRR-REPEAT PROTEIN 15 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=28204|UniProtKB=Q9BSD7 Q9BSD7 NTPCR PTHR43146:SF1 CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE phosphatase#PC00181 HUMAN|HGNC=26620|UniProtKB=Q6Q759 Q6Q759 SPAG17 PTHR21963:SF1 PF6 SPERM-ASSOCIATED ANTIGEN 17 vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;axonemal central apparatus#GO:1990716;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=28524|UniProtKB=Q8NCS7 Q8NCS7 SLC44A5 PTHR12385:SF42 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN 5 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;cellular process#GO:0009987;transmembrane transport#GO:0055085;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 HUMAN|HGNC=5473|UniProtKB=P22692 P22692 IGFBP4 PTHR11551:SF7 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 4 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=11930|UniProtKB=O43557 O43557 TNFSF14 PTHR11471:SF34 TUMOR NECROSIS FACTOR FAMILY MEMBER TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 HUMAN|HGNC=26185|UniProtKB=Q9H6E4 Q9H6E4 CCDC134 PTHR14735:SF1 UNCHARACTERIZED COILED-COIL DOMAIN-CONTAINING PROTEIN 134 HUMAN|HGNC=19096|UniProtKB=Q8NDX1 Q8NDX1 PSD4 PTHR10663:SF338 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN 4 cell leading edge#GO:0031252;ruffle membrane#GO:0032587;ruffle#GO:0001726;leading edge membrane#GO:0031256;plasma membrane region#GO:0098590;cell projection membrane#GO:0031253;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=19628|UniProtKB=Q8NH09 Q8NH09 OR8S1 PTHR48001:SF103 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8S1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=24203|UniProtKB=Q8WZ82 Q8WZ82 OVCA2 PTHR48070:SF6 ESTERASE OVCA2 ESTERASE OVCA2 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 esterase#PC00097 HUMAN|HGNC=21314|UniProtKB=Q8WXC6 Q8WXC6 COPS9 PTHR28562:SF3 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of biological process#GO:0050789;negative regulation of protein modification process#GO:0031400;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;COP9 signalosome#GO:0008180;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=11642|UniProtKB=P37275 P37275 ZEB1 PTHR24391:SF17 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER E-BOX-BINDING HOMEOBOX 1 C2H2 zinc finger transcription factor#PC00248 Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#G06670;Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#G06884;Gonadotropin-releasing hormone receptor pathway#P06664>Zeb1#P06783 HUMAN|HGNC=6855|UniProtKB=Q99759 Q99759 MAP3K3 PTHR24361:SF656 MITOGEN-ACTIVATED KINASE KINASE KINASE MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 Integrin signalling pathway#P00034>ERK#P00907;B cell activation#P00010>MEKK#P00369;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;FGF signaling pathway#P00021>MEKK1-5#P00634;EGF receptor signaling pathway#P00018>MEKK1-5#P00553 HUMAN|HGNC=23791|UniProtKB=Q27J81 Q27J81 INF2 PTHR46345:SF1 INVERTED FORMIN-2 INVERTED FORMIN-2 HUMAN|HGNC=35454|UniProtKB=Q19T08 Q19T08 ECSCR PTHR28602:SF1 ENDOTHELIAL CELL-SPECIFIC CHEMOTAXIS REGULATOR ENDOTHELIAL CELL-SPECIFIC CHEMOTAXIS REGULATOR HUMAN|HGNC=23672|UniProtKB=Q5VZR4 Q5VZR4 MFSD14C PTHR23504:SF32 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 HIPPOCAMPUS ABUNDANT TRANSCRIPT-LIKE PROTEIN 1-RELATED HUMAN|HGNC=43618|UniProtKB=A8MWK0 A8MWK0 FADS2B PTHR19353:SF22 FATTY ACID DESATURASE 2 FATTY ACID DESATURASE 2-LIKE PROTEIN FADS2B-RELATED HUMAN|HGNC=10770|UniProtKB=Q15393 Q15393 SF3B3 PTHR10644:SF1 DNA REPAIR/RNA PROCESSING CPSF FAMILY SPLICING FACTOR 3B SUBUNIT 3 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;organic substance metabolic process#GO:0071704;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=13388|UniProtKB=Q00994 Q00994 BEX3 PTHR19430:SF1 PROTEIN BEX1-RELATED PROTEIN BEX3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=4139|UniProtKB=Q8TET4 Q8TET4 GANC PTHR22762:SF60 ALPHA-GLUCOSIDASE NEUTRAL ALPHA-GLUCOSIDASE C glucosidase#PC00108 HUMAN|HGNC=5330|UniProtKB=P41252 P41252 IARS1 PTHR42780:SF1 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=18163|UniProtKB=Q86WN2 Q86WN2 IFNE PTHR11691:SF8 TYPE I INTERFERON INTERFERON EPSILON receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein-containing complex binding#GO:0044877;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;B cell proliferation#GO:0042100;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;B cell activation#GO:0042113;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;lymphocyte activation involved in immune response#GO:0002285;cellular developmental process#GO:0048869;cellular response to organic substance#GO:0071310;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;cell activation involved in immune response#GO:0002263;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;B cell differentiation#GO:0030183;positive regulation of phosphate metabolic process#GO:0045937;leukocyte activation involved in immune response#GO:0002366;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;T cell activation involved in immune response#GO:0002286;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;humoral immune response#GO:0006959;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of receptor signaling pathway via STAT#GO:1904892;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;lymphocyte differentiation#GO:0030098;regulation of cellular protein metabolic process#GO:0032268;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;T cell activation#GO:0042110;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interferon superfamily#PC00127 HUMAN|HGNC=10909|UniProtKB=Q9NP59 Q9NP59 SLC40A1 PTHR11660:SF47 SOLUTE CARRIER FAMILY 40 MEMBER SOLUTE CARRIER FAMILY 40 MEMBER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;peptide hormone binding#GO:0017046;transmembrane transporter activity#GO:0022857;iron ion transmembrane transporter activity#GO:0005381;binding#GO:0005488;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;amide binding#GO:0033218;peptide binding#GO:0042277;ion transmembrane transporter activity#GO:0015075;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;iron ion transmembrane transport#GO:0034755;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;iron ion homeostasis#GO:0055072;biological regulation#GO:0065007;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;metal ion homeostasis#GO:0055065 plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=2682|UniProtKB=Q9NQZ3 Q9NQZ3 DAZ1 PTHR11176:SF8 BOULE-RELATED DELETED IN AZOOSPERMIA PROTEIN 1-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of translational initiation#GO:0045948;gene expression#GO:0010467;regulation of translational initiation#GO:0006446;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;peptide biosynthetic process#GO:0043043;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of RNA metabolic process#GO:0051253;peptide metabolic process#GO:0006518;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;translation#GO:0006412;cellular nitrogen compound catabolic process#GO:0044270;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of cellular catabolic process#GO:0031330;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of cellular biosynthetic process#GO:0031326;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;translational initiation#GO:0006413;positive regulation of cellular protein metabolic process#GO:0032270;cellular macromolecule catabolic process#GO:0044265;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=13501|UniProtKB=Q9HBT8 Q9HBT8 ZNF286A PTHR24377:SF217 IP01015P-RELATED ZINC FINGER PROTEIN 286A-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=31136|UniProtKB=Q4VC31 Q4VC31 CCDC58 PTHR31905:SF4 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12820|UniProtKB=Q9GZR2 Q9GZR2 REXO4 PTHR12801:SF130 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 4 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;cellular macromolecule metabolic process#GO:0044260;DNA catabolic process#GO:0006308;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;DNA catabolic process, endonucleolytic#GO:0000737;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;non-recombinational repair#GO:0000726;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular response to stress#GO:0033554;cellular macromolecule catabolic process#GO:0044265;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 exoribonuclease#PC00099 HUMAN|HGNC=12907|UniProtKB=Q15973 Q15973 ZNF124 PTHR24381:SF136 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 124 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=25621|UniProtKB=Q9NUZ1 Q9NUZ1 ACOXL PTHR10909:SF378 ELECTRON TRANSPORT OXIDOREDUCTASE ACYL-COENZYME A OXIDASE-LIKE PROTEIN nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;regulation of biological quality#GO:0065008;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;cellular process#GO:0009987;chemical homeostasis#GO:0048878;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;lipid homeostasis#GO:0055088;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176 HUMAN|HGNC=1805|UniProtKB=P47902 P47902 CDX1 PTHR24332:SF16 HOMEOBOX PROTEIN CDX HOMEOBOX PROTEIN CDX-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;animal organ morphogenesis#GO:0009887;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=11268|UniProtKB=Q9UBC9 Q9UBC9 SPRR3 PTHR23263:SF138 SMALL PROLINE-RICH PROTEIN SMALL PROLINE-RICH PROTEIN 3 HUMAN|HGNC=31394|UniProtKB=Q6P1K8 Q6P1K8 GTF2H2C PTHR12695:SF2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;nucleotide-excision repair#GO:0006289;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;cellular response to stress#GO:0033554;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II transcription regulator complex#GO:0090575;protein kinase complex#GO:1902911;transcription factor TFIIH core complex#GO:0000439;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;transcription factor TFIIH holo complex#GO:0005675 general transcription factor#PC00259 HUMAN|HGNC=12230|UniProtKB=A0A0K0K1A5 A0A0K0K1A5 TRBV6-5 PTHR23268:SF19 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 6-2-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=3208|UniProtKB=P24534 P24534 EEF1B2 PTHR11595:SF60 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-BETA GTPase binding#GO:0051020;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation elongation factor#PC00222 HUMAN|HGNC=18747|UniProtKB=Q9C0A0 Q9C0A0 CNTNAP4 PTHR15036:SF40 PIKACHURIN-LIKE PROTEIN CONTACTIN-ASSOCIATED PROTEIN-LIKE 4 HUMAN|HGNC=10500|UniProtKB=P04271 P04271 S100B PTHR11639:SF134 S100 CALCIUM-BINDING PROTEIN PROTEIN S100-A1-RELATED calmodulin-related#PC00061 HUMAN|HGNC=29807|UniProtKB=Q6PF18 Q6PF18 MORN3 PTHR46511:SF1 MORN REPEAT-CONTAINING PROTEIN 3 MORN REPEAT-CONTAINING PROTEIN 3 HUMAN|HGNC=14581|UniProtKB=Q9BXM7 Q9BXM7 PINK1 PTHR22972:SF7 SERINE/THREONINE PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE PINK1, MITOCHONDRIAL transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 positive regulation of organelle organization#GO:0010638;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;autophagy of mitochondrion#GO:0000422;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;cellular component disassembly#GO:0022411;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of mitochondrion organization#GO:0010821;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;phosphorylation#GO:0016310;mitochondrion organization#GO:0007005;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;organelle disassembly#GO:1903008;positive regulation of developmental process#GO:0051094;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of cellular component organization#GO:0051130;organelle fission#GO:0048285;autophagy#GO:0006914;mitochondrial fission#GO:0000266 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=2753|UniProtKB=Q16698 Q16698 DECR1 PTHR43658:SF8 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 2,4-DIENOYL-COA REDUCTASE, MITOCHONDRIAL-RELATED oxidoreductase#PC00176 HUMAN|HGNC=26439|UniProtKB=Q86VL8 Q86VL8 SLC47A2 PTHR11206:SF81 MULTIDRUG RESISTANCE PROTEIN MULTIDRUG AND TOXIN EXTRUSION PROTEIN 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical entity#GO:0110165;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=14580|UniProtKB=O15085 O15085 ARHGEF11 PTHR45872:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 11 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=28898|UniProtKB=Q7Z4H4 Q7Z4H4 ADM2 PTHR23414:SF2 ADRENOMEDULLIN, ADM PROTEIN ADM2 peptide hormone#PC00179 HUMAN|HGNC=24854|UniProtKB=O95210 O95210 STBD1 PTHR15048:SF0 STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1 STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=31855|UniProtKB=Q5JQD4 Q5JQD4 PYY3 PTHR10533:SF14 NEUROPEPTIDE Y/PANCREATIC HORMONE/PEPTIDE YY PEPTIDE YY-RELATED neuropeptide hormone activity#GO:0005184;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;neuropeptide signaling pathway#GO:0007218;behavior#GO:0007610;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intercellular signal molecule#PC00207 HUMAN|HGNC=4830|UniProtKB=P02100 P02100 HBE1 PTHR11442:SF7 HEMOGLOBIN FAMILY MEMBER HEMOGLOBIN SUBUNIT EPSILON small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;organic acid binding#GO:0043177;transporter activity#GO:0005215;oxidoreductase activity#GO:0016491;heme binding#GO:0020037 catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular space#GO:0005615;intracellular#GO:0005622;extracellular region#GO:0005576 HUMAN|HGNC=24594|UniProtKB=Q9BTE1 Q9BTE1 DCTN5 PTHR46126:SF2 DYNACTIN SUBUNIT 5 DYNACTIN SUBUNIT 5 microtubule binding motor protein#PC00156 HUMAN|HGNC=33128|UniProtKB=Q86TX2 Q86TX2 ACOT1 PTHR10824:SF16 ACYL-COENZYME A THIOESTERASE-RELATED ACYL-COENZYME A THIOESTERASE 1-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;purine ribonucleotide metabolic process#GO:0009150;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 esterase#PC00097 HUMAN|HGNC=6899|UniProtKB=P04201 P04201 MAS1 PTHR11334:SF61 MAS-RELATED G-PROTEIN COUPLED RECEPTOR PROTO-ONCOGENE MAS signaling receptor activity#GO:0038023;binding#GO:0005488;peptide binding#GO:0042277;amide binding#GO:0033218;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=5467|UniProtKB=P11717 P11717 IGF2R PTHR15071:SF17 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 Apoptosis signaling pathway#P00006>IGFR2#P00282;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885 HUMAN|HGNC=12754|UniProtKB=O75083 O75083 WDR1 PTHR19856:SF0 WD-REPEATCONTAINING PROTEIN WDR1 WD REPEAT-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular protein complex disassembly#GO:0043624;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;protein-containing complex disassembly#GO:0032984;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;actin filament depolymerization#GO:0030042;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=21175|UniProtKB=A2A288 A2A288 ZC3H12D PTHR12876:SF11 N4BP1-RELATED RIBONUCLEASE ZC3H12D-RELATED catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;endoribonuclease activity#GO:0004521;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA phosphodiester bond hydrolysis#GO:0090501;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;RNA phosphodiester bond hydrolysis, endonucleolytic#GO:0090502;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleic acid phosphodiester bond hydrolysis#GO:0090305;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 endoribonuclease#PC00094 HUMAN|HGNC=15563|UniProtKB=Q9NZH6 Q9NZH6 IL37 PTHR10078:SF31 INTERLEUKIN-1 FAMILY MEMBER INTERLEUKIN-37 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of gene expression#GO:0010628;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to lipopolysaccharide#GO:0071222;gene expression#GO:0010467;response to lipid#GO:0033993;inflammatory response#GO:0006954;cellular response to lipid#GO:0071396;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;positive regulation of metabolic process#GO:0009893;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;immune response#GO:0006955;macromolecule metabolic process#GO:0043170;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;response to lipopolysaccharide#GO:0032496;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 interleukin superfamily#PC00128 HUMAN|HGNC=16318|UniProtKB=Q6NXS1 Q6NXS1 PPP1R2B PTHR12398:SF27 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE INHIBITOR 2 FAMILY MEMBER B hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096;protein phosphatase inhibitor activity#GO:0004864 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;regulation of phosphoprotein phosphatase activity#GO:0043666;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of phosphatase activity#GO:0010921;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 phosphatase inhibitor#PC00183 HUMAN|HGNC=25856|UniProtKB=Q9H825 Q9H825 METTL8 PTHR22809:SF3 METHYLTRANSFERASE-RELATED MRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL8 tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 methyltransferase#PC00155 HUMAN|HGNC=6076|UniProtKB=Q14642 Q14642 INPP5A PTHR12997:SF2 TYPE I INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE INOSITOL POLYPHOSPHATE-5-PHOSPHATASE A inositol phosphate phosphatase activity#GO:0052745;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;cellular metabolic process#GO:0044237;cell communication#GO:0007154;alcohol metabolic process#GO:0006066;inositol phosphate-mediated signaling#GO:0048016;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;intracellular signal transduction#GO:0035556;signaling#GO:0023052;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphatase#PC00181 PI3 kinase pathway#P00048>SHIP#P01200 HUMAN|HGNC=257|UniProtKB=P55263 P55263 ADK PTHR45769:SF3 ADENOSINE KINASE ADENOSINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25705|UniProtKB=Q8N5Z5 Q8N5Z5 KCTD17 PTHR14958:SF24 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD17 protein binding#GO:0005515;binding#GO:0005488 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;protein catabolic process#GO:0030163;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;establishment of vesicle localization#GO:0051650;proteolysis#GO:0006508;cytoskeleton organization#GO:0007010;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cilium assembly#GO:0060271;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;primary metabolic process#GO:0044238;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;regulation of cell projection organization#GO:0031344;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;macromolecule localization#GO:0033036;positive regulation of cell projection organization#GO:0031346;positive regulation of organelle organization#GO:0010638;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound catabolic process#GO:1901565;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;positive regulation of cellular component biogenesis#GO:0044089;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;vesicle localization#GO:0051648;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;intraciliary transport involved in cilium assembly#GO:0035735;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular protein catabolic process#GO:0044257;regulation of cell projection assembly#GO:0060491;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 HUMAN|HGNC=3776|UniProtKB=P51816 P51816 AFF2 PTHR10528:SF18 AF4/FMR2 FAMILY MEMBER AF4/FMR2 FAMILY MEMBER 2 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=20130|UniProtKB=Q8NBD8 Q8NBD8 TMEM229B PTHR31746:SF3 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229B HUMAN|HGNC=1087|UniProtKB=Q9UMX3 Q9UMX3 BOK PTHR11256:SF48 BCL-2 RELATED BCL-2-RELATED OVARIAN KILLER PROTEIN identical protein binding#GO:0042802;protein binding#GO:0005515;protein homodimerization activity#GO:0042803;binding#GO:0005488 intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;extrinsic apoptotic signaling pathway in absence of ligand#GO:0097192;intracellular signal transduction#GO:0035556;cellular response to stress#GO:0033554;signaling#GO:0023052 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 Apoptosis signaling pathway#P00006>Bok#P00261 HUMAN|HGNC=28591|UniProtKB=Q96MH2 Q96MH2 HEXIM2 PTHR13469:SF3 HEXAMETHYLENE BISACETAMIDE INDUCIBLE 1 PROTEIN HEXIM2 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;nucleic acid binding#GO:0003676;protein kinase regulator activity#GO:0019887;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;snRNA binding#GO:0017069;cyclin binding#GO:0030332;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234;kinase activity#GO:0016301;kinase binding#GO:0019900;protein kinase activity#GO:0004672;RNA binding#GO:0003723;cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;protein kinase inhibitor activity#GO:0004860 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;regulation of cyclin-dependent protein kinase activity#GO:1904029;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of protein kinase activity#GO:0006469;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cyclin-dependent protein serine/threonine kinase activity#GO:0000079;nucleic acid-templated transcription#GO:0097659;regulation of protein kinase activity#GO:0045859;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;negative regulation of phosphorus metabolic process#GO:0010563;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;protein phosphorylation#GO:0006468;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;regulation of nucleic acid-templated transcription#GO:1903506;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of molecular function#GO:0044092 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29377|UniProtKB=Q5H9K5 Q5H9K5 ZMAT1 PTHR46742:SF2 LYSINE-RICH COILED-COIL PROTEIN 1 ZINC FINGER MATRIN-TYPE PROTEIN 1 HUMAN|HGNC=28403|UniProtKB=Q8TBZ6 Q8TBZ6 TRMT10A PTHR13563:SF18 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG A tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;heterocyclic compound binding#GO:1901363;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 HUMAN|HGNC=14941|UniProtKB=Q96I34 Q96I34 PPP1R16A PTHR24186:SF7 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 16A hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;protein phosphatase 1 binding#GO:0008157;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 phosphatase modulator#PC00184 HUMAN|HGNC=9778|UniProtKB=P20337 P20337 RAB3B PTHR47980:SF22 LD44762P RAS-RELATED PROTEIN RAB-3B vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;protein secretion#GO:0009306;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=6154|UniProtKB=Q9UKP3 Q9UKP3 ITGB1BP2 PTHR12621:SF8 CYSTEINE AND HISTIDINE-RICH DOMAIN CHORD -CONTAINING PROTEIN INTEGRIN BETA-1-BINDING PROTEIN 2 cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023 scaffold/adaptor protein#PC00226 HUMAN|Ensembl=ENSG00000283722|UniProtKB=A0A191URJ7 A0A191URJ7 KIR2DL1 PTHR11738:SF113 MHC CLASS I NK CELL RECEPTOR KIR2DL PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=14634|UniProtKB=Q13442 Q13442 PDAP1 PTHR22055:SF5 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=28587|UniProtKB=Q8TC76 Q8TC76 FAM110B PTHR14758:SF2 AGAP005440-PA PROTEIN FAM110B HUMAN|HGNC=6171|UniProtKB=Q08881 Q08881 ITK PTHR24418:SF61 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ITK/TSK protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;B cell receptor signaling pathway#GO:0050853;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;alpha-beta T cell differentiation#GO:0046632;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;regulation of immune response#GO:0050776;cellular metabolic process#GO:0044237;cell communication#GO:0007154;T cell differentiation#GO:0030217;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;immune response-activating cell surface receptor signaling pathway#GO:0002429;signal transduction#GO:0007165;macromolecule modification#GO:0043412;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;cell differentiation#GO:0030154;system development#GO:0048731;adaptive immune response#GO:0002250;protein autophosphorylation#GO:0046777;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;protein phosphorylation#GO:0006468;cellular process#GO:0009987;response to stimulus#GO:0050896;immune system process#GO:0002376;lymphocyte differentiation#GO:0030098;peptidyl-tyrosine modification#GO:0018212;T cell activation#GO:0042110;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;T cell receptor signaling pathway#GO:0050852 HUMAN|HGNC=16037|UniProtKB=Q53FV1 Q53FV1 ORMDL2 PTHR12665:SF13 ORMDL PROTEINS ORM1-LIKE PROTEIN 2 negative regulation of cellular metabolic process#GO:0031324;lipid metabolic process#GO:0006629;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;regulation of nitrogen compound metabolic process#GO:0051171;biosynthetic process#GO:0009058;cellular homeostasis#GO:0019725;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;regulation of cellular component biogenesis#GO:0044087;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of lipid biosynthetic process#GO:0046890;negative regulation of cellular process#GO:0048523;sphingolipid biosynthetic process#GO:0030148;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;chemical homeostasis#GO:0048878;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;cellular chemical homeostasis#GO:0055082;cellular component organization or biogenesis#GO:0071840;regulation of cellular biosynthetic process#GO:0031326;membrane lipid metabolic process#GO:0006643;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;ceramide biosynthetic process#GO:0046513;biological regulation#GO:0065007;lipid homeostasis#GO:0055088;regulation of lipid metabolic process#GO:0019216;cellular lipid metabolic process#GO:0044255;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=9603|UniProtKB=Q16647 Q16647 PTGIS PTHR24306:SF4 FAMILY NOT NAMED PROSTACYCLIN SYNTHASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;icosanoid metabolic process#GO:0006690;icosanoid biosynthetic process#GO:0046456;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid derivative metabolic process#GO:1901568;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;unsaturated fatty acid biosynthetic process#GO:0006636;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704 HUMAN|HGNC=24017|UniProtKB=Q8N556 Q8N556 AFAP1 PTHR14338:SF8 ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER ACTIN FILAMENT-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=14722|UniProtKB=Q8NGS5 Q8NGS5 OR13C4 PTHR26453:SF14 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13C4 transmembrane signal receptor#PC00197 HUMAN|HGNC=1703|UniProtKB=Q01151 Q01151 CD83 PTHR15193:SF1 CD83 ANTIGEN CD83 ANTIGEN HUMAN|HGNC=22204|UniProtKB=Q96HN2 Q96HN2 AHCYL2 PTHR23420:SF2 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE 3 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 hydrolase#PC00121 HUMAN|HGNC=12662|UniProtKB=P61758 P61758 VBP1 PTHR12409:SF0 PREFOLDIN SUBUNIT 3 PREFOLDIN SUBUNIT 3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;microtubule-based process#GO:0007017;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;polysome#GO:0005844;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=19076|UniProtKB=O95873 O95873 C6orf47 PTHR14307:SF0 C6ORF47 FAMILY MEMBER SI:CH73-25F10.6 HUMAN|HGNC=13433|UniProtKB=Q96MS0 Q96MS0 ROBO3 PTHR10075:SF37 BASIGIN RELATED ROUNDABOUT HOMOLOG 3 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 neuron projection guidance#GO:0097485;cell recognition#GO:0008037;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;biological adhesion#GO:0022610;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;homophilic cell adhesion via plasma membrane adhesion molecules#GO:0007156;multicellular organism development#GO:0007275;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 neuron projection#GO:0043005;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Axon guidance mediated by Slit/Robo#P00008>Robo#P00348 HUMAN|HGNC=29632|UniProtKB=Q8WZ59 Q8WZ59 TMEM190 PTHR37868:SF1 TRANSMEMBRANE PROTEIN 190 TRANSMEMBRANE PROTEIN 190 immune system process#GO:0002376;system development#GO:0048731;cell differentiation#GO:0030154;cellular developmental process#GO:0048869;immune system development#GO:0002520;anatomical structure development#GO:0048856;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;hematopoietic or lymphoid organ development#GO:0048534;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;membrane region#GO:0098589;plasma membrane#GO:0005886 HUMAN|HGNC=7734|UniProtKB=P07197 P07197 NEFM PTHR45652:SF3 GLIAL FIBRILLARY ACIDIC PROTEIN NEUROFILAMENT MEDIUM POLYPEPTIDE HUMAN|HGNC=6075|UniProtKB=O15327 O15327 INPP4B PTHR12187:SF3 AGAP000124-PA INOSITOL POLYPHOSPHATE 4-PHOSPHATASE TYPE II hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=15997|UniProtKB=Q8IVL1 Q8IVL1 NAV2 PTHR12784:SF6 STEERIN NEURON NAVIGATOR 2 system development#GO:0048731;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 HUMAN|HGNC=2907|UniProtKB=P80370 P80370 DLK1 PTHR24052:SF11 DELTA-RELATED PROTEIN DELTA HOMOLOG 1 cellular anatomical entity#GO:0110165;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 HUMAN|HGNC=20812|UniProtKB=Q9NX65 Q9NX65 ZSCAN32 PTHR23226:SF209 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 32 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=17675|UniProtKB=Q9HAV4 Q9HAV4 XPO5 PTHR11223:SF3 EXPORTIN 1/5 EXPORTIN-5 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;transporter activity#GO:0005215;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;regulation of protein transport#GO:0051223;nuclear transport#GO:0051169;regulation of protein localization#GO:0032880;establishment of RNA localization#GO:0051236;peptide transport#GO:0015833;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;regulation of cellular process#GO:0050794;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transporter#PC00227 HUMAN|HGNC=960|UniProtKB=Q9NRL2 Q9NRL2 BAZ1A PTHR46510:SF1 BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A HUMAN|HGNC=12723|UniProtKB=Q9NZR4 Q9NZR4 VSX1 PTHR24323:SF3 CEH-10 HOMEODOMAIN-CONTAINING HOMOLOG VISUAL SYSTEM HOMEOBOX 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=30655|UniProtKB=Q8N0Z2 Q8N0Z2 ABRA PTHR22739:SF20 STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED ACTIN-BINDING RHO-ACTIVATING PROTEIN positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;Ras protein signal transduction#GO:0007265;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of Rho protein signal transduction#GO:0035023;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;regulation of small GTPase mediated signal transduction#GO:0051056;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;small GTPase mediated signal transduction#GO:0007264;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;aromatic compound biosynthetic process#GO:0019438;regulation of Ras protein signal transduction#GO:0046578;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;Rho protein signal transduction#GO:0007266;positive regulation of DNA-binding transcription factor activity#GO:0051091;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;sarcomere#GO:0030017;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;organelle#GO:0043226;contractile fiber#GO:0043292;myofibril#GO:0030016;intracellular organelle#GO:0043229 HUMAN|HGNC=11523|UniProtKB=O95359 O95359 TACC2 PTHR13924:SF11 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 2 head development#GO:0060322;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;brain development#GO:0007420;cellular component organization#GO:0016043;cellular process#GO:0009987;nervous system development#GO:0007399;cell population proliferation#GO:0008283;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;forebrain development#GO:0030900;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;central nervous system development#GO:0007417 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=15030|UniProtKB=Q8NGY3 Q8NGY3 OR6K3 PTHR26451:SF956 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 6K3 HUMAN|HGNC=16798|UniProtKB=Q5VY80 Q5VY80 RAET1L PTHR16675:SF148 MHC CLASS I-RELATED UL16-BINDING PROTEIN 2-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=16163|UniProtKB=Q8IUA0 Q8IUA0 WFDC8 PTHR47769:SF1 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 8 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 8 HUMAN|HGNC=14141|UniProtKB=Q96S19 Q96S19 METTL26 PTHR20974:SF2 UNCHARACTERIZED METHYLTRANSFERASE-LIKE 26 HUMAN|HGNC=5980|UniProtKB=Q14005 Q14005 IL16 PTHR11324:SF2 IL16-RELATED PRO-INTERLEUKIN-16 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;cellular response to chemical stimulus#GO:0070887;regulation of locomotion#GO:0040012;positive regulation of response to external stimulus#GO:0032103;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;positive regulation of chemotaxis#GO:0050921;localization#GO:0051179;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;leukocyte migration#GO:0050900;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to chemical#GO:0042221;regulation of chemotaxis#GO:0050920;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;positive chemotaxis#GO:0050918;leukocyte chemotaxis#GO:0030595;cell migration#GO:0016477;locomotion#GO:0040011;positive regulation of biological process#GO:0048518;chemotaxis#GO:0006935;taxis#GO:0042330 interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Interleukin#P00970 HUMAN|HGNC=7158|UniProtKB=P39900 P39900 MMP12 PTHR10201:SF267 MATRIX METALLOPROTEINASE MACROPHAGE METALLOELASTASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular component organization or biogenesis#GO:0071840;catabolic process#GO:0009056;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152 metalloprotease#PC00153 Alzheimer disease-presenilin pathway#P00004>Matrix metalloprotease#P00130 HUMAN|HGNC=8077|UniProtKB=O95157 O95157 NXPH3 PTHR17103:SF14 NEUREXOPHILIN NEUREXOPHILIN-3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 intercellular signal molecule#PC00207 HUMAN|HGNC=19039|UniProtKB=Q7Z695 Q7Z695 ADCK2 PTHR45890:SF1 AARF DOMAIN CONTAINING KINASE 2 (PREDICTED) ABC1 DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=43|UniProtKB=Q03518 Q03518 TAP1 PTHR24221:SF249 ATP-BINDING CASSETTE SUB-FAMILY B ANTIGEN PEPTIDE TRANSPORTER 1 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=23409|UniProtKB=Q6UWR7 Q6UWR7 ENPP6 PTHR10151:SF66 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE CHOLINEPHOSPHODIESTERASE ENPP6 HUMAN|HGNC=18072|UniProtKB=Q5HYI8 Q5HYI8 RABL3 PTHR24073:SF128 DRAB5-RELATED RAB-LIKE PROTEIN 3 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=13872|UniProtKB=Q9Y4F9 Q9Y4F9 RIPOR2 PTHR15829:SF2 PROTEIN KINASE PKN/PRK1, EFFECTOR RHO FAMILY-INTERACTING CELL POLARIZATION REGULATOR 2 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=22949|UniProtKB=Q5TB30 Q5TB30 DEPDC1 PTHR16206:SF12 DEP DOMAIN-CONTAINING DEP DOMAIN-CONTAINING PROTEIN 1A scaffold/adaptor protein#PC00226 HUMAN|HGNC=250|UniProtKB=P00325 P00325 ADH1B PTHR43880:SF11 ALCOHOL DEHYDROGENASE ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH1B cation binding#GO:0043169;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 response to organic substance#GO:0010033;organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;generation of precursor metabolites and energy#GO:0006091;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to oxygen-containing compound#GO:1901701;small molecule catabolic process#GO:0044282;response to chemical#GO:0042221;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;response to toxic substance#GO:0009636;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=18900|UniProtKB=Q9BYR5 Q9BYR5 KRTAP4-2 PTHR23262:SF182 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 4-2 HUMAN|HGNC=4459|UniProtKB=P80108 P80108 GPLD1 PTHR23221:SF7 GLYCOSYLPHOSPHATIDYLINOSITOL PHOSPHOLIPASE D PHOSPHATIDYLINOSITOL-GLYCAN-SPECIFIC PHOSPHOLIPASE D phospholipase#PC00186 Gonadotropin-releasing hormone receptor pathway#P06664>PLD#P06839 HUMAN|HGNC=20580|UniProtKB=Q6VVX0 Q6VVX0 CYP2R1 PTHR24300:SF48 CYTOCHROME P450 508A4-RELATED VITAMIN D 25-HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=24617|UniProtKB=Q8NG57 Q8NG57 ELOA3 PTHR15141:SF74 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 ELONGIN-A3-RELATED HUMAN|Ensembl=ENSG00000278263|UniProtKB=A0A087WW49 A0A087WW49 ENSG00000278263 PTHR23266:SF364 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=33906|UniProtKB=Q075Z2 Q075Z2 BSPH1 PTHR22918:SF3 SEMINAL PLASMA PROTEIN BINDER OF SPERM PROTEIN HOMOLOG 1 heparin binding#GO:0008201;carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;binding#GO:0005488 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|HGNC=8529|UniProtKB=P30559 P30559 OXTR PTHR24241:SF89 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OXYTOCIN RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;multicellular organism reproduction#GO:0032504;system process#GO:0003008;regulation of blood vessel diameter#GO:0097746;regulation of system process#GO:0044057;regulation of systemic arterial blood pressure#GO:0003073;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;multi-organism process#GO:0051704;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;reproduction#GO:0000003;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;reproductive process#GO:0022414;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;positive regulation of biological process#GO:0048518;signaling#GO:0023052;multicellular organismal reproductive process#GO:0048609;positive regulation of multicellular organismal process#GO:0051240 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Oxytocin receptor mediated signaling pathway#P04391>Oxytocin Receptor#P04531 HUMAN|HGNC=3666|UniProtKB=O15520 O15520 FGF10 PTHR11486:SF21 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 10 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of MAPK cascade#GO:0043408;regulation of protein metabolic process#GO:0051246;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;positive regulation of cell population proliferation#GO:0008284;regulation of localization#GO:0032879;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of cell migration#GO:0030334;secretion#GO:0046903;epithelial cell proliferation#GO:0050673;positive regulation of epithelial cell proliferation#GO:0050679;cellular protein metabolic process#GO:0044267;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of phosphorylation#GO:0042325;export from cell#GO:0140352;taxis#GO:0042330;signal transduction#GO:0007165;regulation of locomotion#GO:0040012;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;growth#GO:0040007;MAPK cascade#GO:0000165;positive regulation of Wnt signaling pathway#GO:0030177;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of cell motility#GO:2000147;protein metabolic process#GO:0019538;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;Wnt signaling pathway#GO:0016055;chemotaxis#GO:0006935;secretion by cell#GO:0032940;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of protein metabolic process#GO:0051247;positive regulation of cell migration#GO:0030335;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;regulation of protein modification process#GO:0031399;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;regulation of intracellular signal transduction#GO:1902531;positive regulation of cellular component movement#GO:0051272;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;positive regulation of locomotion#GO:0040017;tube development#GO:0035295;positive regulation of cellular process#GO:0048522;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;response to stress#GO:0006950;response to wounding#GO:0009611;positive regulation of phosphate metabolic process#GO:0045937;regulation of ERK1 and ERK2 cascade#GO:0070372;movement of cell or subcellular component#GO:0006928;positive chemotaxis#GO:0050918;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;animal organ development#GO:0048513;transport#GO:0006810;developmental process#GO:0032502;wound healing#GO:0042060;positive regulation of MAPK cascade#GO:0043410;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;response to organic substance#GO:0010033;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;ERK1 and ERK2 cascade#GO:0070371;regulation of cell motility#GO:2000145;developmental growth#GO:0048589;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of Wnt signaling pathway#GO:0030111;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=16085|UniProtKB=Q9H9B4 Q9H9B4 SFXN1 PTHR11153:SF21 SIDEROFLEXIN SIDEROFLEXIN-1 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068 HUMAN|HGNC=1109|UniProtKB=O95415 O95415 BRI3 PTHR13551:SF1 BRAIN PROTEIN I3 BRAIN PROTEIN I3 HUMAN|HGNC=8647|UniProtKB=Q15365 Q15365 PCBP1 PTHR10288:SF96 KH DOMAIN CONTAINING RNA BINDING PROTEIN POLY(RC)-BINDING PROTEIN 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=25666|UniProtKB=Q7L5A3 Q7L5A3 FAM214B PTHR13199:SF12 GH03947P PROTEIN FAM214B HUMAN|HGNC=9759|UniProtKB=P61026 P61026 RAB10 PTHR47980:SF23 LD44762P RAS-RELATED PROTEIN RAB-10 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;TGF-beta signaling pathway#P00052>Ras-GTP#P01280 HUMAN|HGNC=24262|UniProtKB=Q9Y303 Q9Y303 AMDHD2 PTHR11113:SF14 N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar catabolic process#GO:0046348;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 deacetylase#PC00087 N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036 HUMAN|HGNC=7104|UniProtKB=Q99797 Q99797 MIPEP PTHR11804:SF8 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED MITOCHONDRIAL INTERMEDIATE PEPTIDASE hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular amide metabolic process#GO:0043603;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metalloprotease#PC00153 HUMAN|HGNC=10007|UniProtKB=O75783 O75783 RHBDL1 PTHR45840:SF4 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 1 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 HUMAN|HGNC=16087|UniProtKB=Q9BWM7 Q9BWM7 SFXN3 PTHR11153:SF20 SIDEROFLEXIN SIDEROFLEXIN-3 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 envelope#GO:0031975;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068 HUMAN|HGNC=3396|UniProtKB=O15197 O15197 EPHB6 PTHR24416:SF326 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-B RECEPTOR 6 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=15471|UniProtKB=Q9H2A2 Q9H2A2 ALDH8A1 PTHR43720:SF2 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=11923|UniProtKB=P28908 P28908 TNFRSF8 PTHR47497:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 8 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 8 transmembrane signal receptor#PC00197 HUMAN|HGNC=17760|UniProtKB=Q9NP99 Q9NP99 TREM1 PTHR19357:SF0 TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1 TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1 HUMAN|HGNC=28957|UniProtKB=Q8N766 Q8N766 EMC1 PTHR21573:SF0 UNCHARACTERIZED ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 cellular process#GO:0009987;protein folding#GO:0006457 membrane protein complex#GO:0098796;ER membrane protein complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;intrinsic component of endoplasmic reticulum membrane#GO:0031227;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;integral component of endoplasmic reticulum membrane#GO:0030176;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=24554|UniProtKB=Q6UXH9 Q6UXH9 PAMR1 PTHR24254:SF9 PROTHROMBIN INACTIVE SERINE PROTEASE PAMR1 serine protease#PC00203 HUMAN|HGNC=10717|UniProtKB=Q9UBV2 Q9UBV2 SEL1L PTHR11102:SF70 SEL-1-LIKE PROTEIN PROTEIN SEL-1 HOMOLOG 1 HUMAN|HGNC=25491|UniProtKB=Q9P2Q2 Q9P2Q2 FRMD4A PTHR46079:SF3 FERM DOMAIN-CONTAINING PROTEIN 4 FERM DOMAIN-CONTAINING PROTEIN 4A cell junction#GO:0030054;bicellular tight junction#GO:0005923;adherens junction#GO:0005912;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;apical junction complex#GO:0043296 HUMAN|HGNC=28705|UniProtKB=Q8N5W9 Q8N5W9 RFLNB PTHR31848:SF2 FAMILY NOT NAMED REFILIN-B cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 negative regulation of biological process#GO:0048519;animal organ development#GO:0048513;developmental process#GO:0032502;regulation of multicellular organismal development#GO:2000026;skeletal system development#GO:0001501;regulation of cell differentiation#GO:0045595;bone mineralization#GO:0030282;bone development#GO:0060348;regulation of biological process#GO:0050789;system development#GO:0048731;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;biomineral tissue development#GO:0031214;negative regulation of cellular process#GO:0048523;regulation of ossification#GO:0030278;cellular developmental process#GO:0048869;biomineralization#GO:0110148;regulation of multicellular organismal process#GO:0051239;regulation of cell development#GO:0060284;ossification#GO:0001503;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;chondrocyte differentiation#GO:0002062;connective tissue development#GO:0061448;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;tissue development#GO:0009888;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cartilage development#GO:0051216 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 HUMAN|HGNC=13806|UniProtKB=Q9Y4Z2 Q9Y4Z2 NEUROG3 PTHR19290:SF94 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=11628|UniProtKB=O60765 O60765 ZNF354A PTHR24377:SF146 IP01015P-RELATED ZINC FINGER PROTEIN 354A cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|Ensembl=ENSG00000250803|UniProtKB=A0A1B0GTH9 A0A1B0GTH9 LOC100505841 PTHR13555:SF36 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER PROTEIN 474 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=7705|UniProtKB=O43677 O43677 NDUFC1 PTHR17097:SF0 NADH-UBIQUINONE OXIDOREDUCTASE KFYI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C1, MITOCHONDRIAL envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=11639|UniProtKB=P36402 P36402 TCF7 PTHR10373:SF33 TRANSCRIPTION FACTOR 7 FAMILY MEMBER TRANSCRIPTION FACTOR 7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cell-cell signaling#GO:0007267;signaling#GO:0023052;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>TCF#P06701;Angiogenesis#P00005>TCF#P00242;Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Wnt signaling pathway#P00057>TCF#P01437;Alzheimer disease-presenilin pathway#P00004>TCF/LEF#P00143 HUMAN|HGNC=4006|UniProtKB=P04066 P04066 FUCA1 PTHR10030:SF2 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE glycosidase#PC00110 HUMAN|HGNC=14338|UniProtKB=Q9HB20 Q9HB20 PLEKHA3 PTHR10219:SF25 GLYCOLIPID TRANSFER PROTEIN-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 3 binding#GO:0005488;amide binding#GO:0033218;phospholipid transporter activity#GO:0005548;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 amide transport#GO:0042886;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;membrane organization#GO:0061024;transport#GO:0006810;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;lipid localization#GO:0010876;cellular process#GO:0009987;lipid transport#GO:0006869 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 transfer/carrier protein#PC00219 HUMAN|HGNC=24695|UniProtKB=Q5XKK7 Q5XKK7 FAM219B PTHR31281:SF2 FAMILY NOT NAMED PROTEIN FAM219B HUMAN|HGNC=18883|UniProtKB=P59536 P59536 TAS2R41 PTHR11394:SF73 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 41 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=9557|UniProtKB=O00232 O00232 PSMD12 PTHR10855:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;peptidase complex#GO:1905368;organelle lumen#GO:0043233;proteasome accessory complex#GO:0022624;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular organelle lumen#GO:0070013;proteasome complex#GO:0000502;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 HUMAN|HGNC=29560|UniProtKB=Q9P016 Q9P016 THYN1 PTHR14087:SF7 THYMOCYTE NUCLEAR PROTEIN 1 THYMOCYTE NUCLEAR PROTEIN 1 HUMAN|HGNC=26831|UniProtKB=Q8N4C9 Q8N4C9 C17orf78 PTHR36870:SF1 C17ORF78 ISOFORM 2 CHROMOSOME 17 C17ORF78 HOMOLOG HUMAN|HGNC=28040|UniProtKB=Q5U5Q3 Q5U5Q3 MEX3C PTHR23285:SF8 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX3C RNA metabolism protein#PC00031 HUMAN|HGNC=48778|UniProtKB=A0A2R8Y4L2 A0A2R8Y4L2 HNRNPA1P48 PTHR15241:SF293 TRANSFORMER-2-RELATED HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 PSEUDOGENE 48 RNA splicing factor#PC00148 HUMAN|HGNC=29094|UniProtKB=O75153 O75153 CLUH PTHR12601:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3 CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=6132|UniProtKB=P61371 P61371 ISL1 PTHR24204:SF4 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;biosynthetic process#GO:0009058;cell fate specification#GO:0001708;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of gene expression#GO:0010468;cell part morphogenesis#GO:0032990;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;cell morphogenesis#GO:0000902;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#P06791;Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#G06896;Gonadotropin-releasing hormone receptor pathway#P06664>Isl-1#G06682 HUMAN|HGNC=7111|UniProtKB=Q9HBH9 Q9HBH9 MKNK2 PTHR24349:SF254 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;calmodulin binding#GO:0005516;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;protein autophosphorylation#GO:0046777;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 p38 MAPK pathway#P05918>MNK2#P06017;Oxidative stress response#P00046>MNK1/2#P01137;Interleukin signaling pathway#P00036>MNK1/2#P00972;PDGF signaling pathway#P00047>MNK1/2#P01149 HUMAN|HGNC=25289|UniProtKB=Q8IY82 Q8IY82 DRC7 PTHR35249:SF2 DYNEIN REGULATORY COMPLEX SUBUNIT 7 DYNEIN REGULATORY COMPLEX SUBUNIT 7 localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;locomotion#GO:0040011 motile cilium#GO:0031514;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=14253|UniProtKB=P27544 P27544 CERS1 PTHR12560:SF58 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;membrane lipid biosynthetic process#GO:0046467;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;amide biosynthetic process#GO:0043604;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ceramide biosynthetic process#GO:0046513;cellular lipid metabolic process#GO:0044255;sphingolipid biosynthetic process#GO:0030148;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=9159|UniProtKB=Q9UL42 Q9UL42 PNMA2 PTHR23095:SF16 PARANEOPLASTIC ANTIGEN PARANEOPLASTIC ANTIGEN MA2 HUMAN|HGNC=5026|UniProtKB=Q14541 Q14541 HNF4G PTHR24083:SF42 NUCLEAR HORMONE RECEPTOR HEPATOCYTE NUCLEAR FACTOR 4-GAMMA cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=12924|UniProtKB=P17017 P17017 ZNF14 PTHR24379:SF99 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 14 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29561|UniProtKB=Q9H2C2 Q9H2C2 ARV1 PTHR14467:SF0 ARV1 PROTEIN ARV1 sterol metabolic process#GO:0016125;organic hydroxy compound transport#GO:0015850;lipid metabolic process#GO:0006629;cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;sterol transport#GO:0015918;plasma membrane organization#GO:0007009;transport#GO:0006810;endomembrane system organization#GO:0010256;lipid transport#GO:0006869;sphingolipid metabolic process#GO:0006665;organic substance transport#GO:0071702;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;lipid localization#GO:0010876;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic hydroxy compound metabolic process#GO:1901615;intracellular sterol transport#GO:0032366;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane lipid metabolic process#GO:0006643;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255 endoplasmic reticulum tubular network#GO:0071782;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;cortical endoplasmic reticulum#GO:0032541;plasma membrane#GO:0005886 HUMAN|HGNC=19400|UniProtKB=Q8N328 Q8N328 PGBD3 PTHR47055:SF2 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 2-RELATED sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 HUMAN|HGNC=23533|UniProtKB=Q5VWI1 Q5VWI1 TCERG1L PTHR15377:SF5 TRANSCRIPTION ELONGATION REGULATOR 1 TRANSCRIPTION ELONGATION REGULATOR 1-LIKE PROTEIN enzyme binding#GO:0019899;transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription regulator activity#GO:0140110;RNA polymerase binding#GO:0070063;binding#GO:0005488 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 general transcription factor#PC00259 HUMAN|HGNC=24644|UniProtKB=Q9UPR3 Q9UPR3 SMG5 PTHR15696:SF7 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 PROTEIN SMG5 sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;telomeric DNA binding#GO:0042162;heterocyclic compound binding#GO:1901363;telomerase RNA binding#GO:0070034 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;telomerase holoenzyme complex#GO:0005697;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=24751|UniProtKB=Q3KQV3 Q3KQV3 ZNF792 PTHR24377:SF662 IP01015P-RELATED ZINC FINGER PROTEIN 792 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=27168|UniProtKB=Q6NUI2 Q6NUI2 GPAT2 PTHR12563:SF15 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 2, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;RNA metabolic process#GO:0016070;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;acylglycerol metabolic process#GO:0006639;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;neutral lipid metabolic process#GO:0006638;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;triglyceride biosynthetic process#GO:0019432;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;triglyceride metabolic process#GO:0006641;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 envelope#GO:0031975;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 acyltransferase#PC00042 HUMAN|HGNC=28605|UniProtKB=Q8N9S9 Q8N9S9 SNX31 PTHR12431:SF15 SORTING NEXIN 17 AND 27 SORTING NEXIN-31 lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;retrograde transport, endosome to plasma membrane#GO:1990126;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=12236|UniProtKB=A0A1B0GXF2 A0A1B0GXF2 TRBV7-2 PTHR23268:SF108 T-CELL RECEPTOR BETA CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=24790|UniProtKB=Q6ZSC3 Q6ZSC3 RBM43 PTHR15225:SF8 INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN RNA-BINDING PROTEIN 43 transcription cofactor#PC00217 HUMAN|HGNC=4881|UniProtKB=Q9UBP5 Q9UBP5 HEY2 PTHR10985:SF88 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY/ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;regulation of cell differentiation#GO:0045595;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;signaling#GO:0023052;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;Notch signaling pathway#GO:0007219 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 HUMAN|HGNC=12491|UniProtKB=P61081 P61081 UBE2M PTHR24068:SF132 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBC12 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=10635|UniProtKB=P80075 P80075 CCL8 PTHR12015:SF168 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 8 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=24521|UniProtKB=Q5GLZ8 Q5GLZ8 HERC4 PTHR45622:SF5 UBIQUITIN-PROTEIN LIGASE E3A-RELATED E3 UBIQUITIN-PROTEIN LIGASE HERC4-RELATED ubiquitin-protein ligase#PC00234 HUMAN|HGNC=27482|UniProtKB=Q4G148 Q4G148 GXYLT1 PTHR46012:SF3 IP22168P GLUCOSIDE XYLOSYLTRANSFERASE 1 UDP-xylosyltransferase activity#GO:0035252;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;xylosyltransferase activity#GO:0042285;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 HUMAN|HGNC=10993|UniProtKB=Q9H2B4 Q9H2B4 SLC26A1 PTHR11814:SF31 SULFATE TRANSPORTER SULFATE ANION TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;inorganic anion transmembrane transporter activity#GO:0015103;active ion transmembrane transporter activity#GO:0022853 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=31440|UniProtKB=Q5SQS7 Q5SQS7 SH2D4B PTHR14388:SF7 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 4B cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 defense/immunity protein#PC00090 HUMAN|HGNC=8045|UniProtKB=Q9Y266 Q9Y266 NUDC PTHR12356:SF3 NUCLEAR MOVEMENT PROTEIN NUDC NUCLEAR MIGRATION PROTEIN NUDC protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 HUMAN|HGNC=26427|UniProtKB=Q96ND8 Q96ND8 ZNF583 PTHR24377:SF863 IP01015P-RELATED ZINC FINGER PROTEIN 583 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=30916|UniProtKB=Q8TEU8 Q8TEU8 WFIKKN2 PTHR45938:SF7 ACP24A4-RELATED WAP, KAZAL, IMMUNOGLOBULIN, KUNITZ AND NTR DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=897|UniProtKB=P30518 P30518 AVPR2 PTHR24241:SF20 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR VASOPRESSIN V2 RECEPTOR signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of anatomical structure size#GO:0090066;blood circulation#GO:0008015;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;system process#GO:0003008;regulation of blood vessel diameter#GO:0097746;regulation of system process#GO:0044057;regulation of systemic arterial blood pressure#GO:0003073;cell communication#GO:0007154;cellular process#GO:0009987;circulatory system process#GO:0003013;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;regulation of blood pressure#GO:0008217;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of multicellular organismal process#GO:0051240 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=8691|UniProtKB=Q9Y5E3 Q9Y5E3 PCDHB6 PTHR24028:SF104 CADHERIN-87A PROTOCADHERIN BETA-6 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=3043|UniProtKB=O95456 O95456 PSMG1 PTHR15069:SF1 PROTEASOME ASSEMBLY CHAPERONE 1 PROTEASOME ASSEMBLY CHAPERONE 1 proteasome binding#GO:0070628;protein-containing complex binding#GO:0044877;binding#GO:0005488 proteasome assembly#GO:0043248;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 chaperone#PC00072 HUMAN|HGNC=26758|UniProtKB=Q7Z3I7 Q7Z3I7 ZNF572 PTHR24399:SF9 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER PROTEIN 572 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=785|UniProtKB=P18847 P18847 ATF3 PTHR23351:SF23 FOS TRANSCRIPTION FACTOR-RELATED CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 Apoptosis signaling pathway#P00006>ATF#P00302;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#G06902;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#P06821;Gonadotropin-releasing hormone receptor pathway#P06664>Atf3#G06689 HUMAN|HGNC=10858|UniProtKB=O43255 O43255 SIAH2 PTHR45877:SF4 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 ubiquitin-like protein conjugating enzyme binding#GO:0044390;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Wnt signaling pathway#P00057>SIAH-1#P01433 HUMAN|HGNC=18251|UniProtKB=Q8IZQ5 Q8IZQ5 SELENOH PTHR33638:SF1 SELENOPROTEIN H SELENOPROTEIN H cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=28422|UniProtKB=Q8NCE0 Q8NCE0 TSEN2 PTHR21227:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on a tRNA#GO:0140101 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 endodeoxyribonuclease#PC00093 HUMAN|HGNC=5662|UniProtKB=A0A0B4J1U7 A0A0B4J1U7 IGHV6-1 PTHR23266:SF323 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=3086|UniProtKB=O14641 O14641 DVL2 PTHR10878:SF8 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-2 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling by wnt#GO:0198738;canonical Wnt signaling pathway#GO:0060070;cell-cell signaling#GO:0007267;signaling#GO:0023052;Wnt signaling pathway#GO:0016055 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Alzheimer disease-presenilin pathway#P00004>Dsh#P00132;Wnt signaling pathway#P00057>Dishevelled#P01447 HUMAN|HGNC=12592|UniProtKB=P10746 P10746 UROS PTHR12390:SF0 UROPORPHYRINOGEN III SYNTHASE UROPORPHYRINOGEN-III SYNTHASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;pigment metabolic process#GO:0042440;porphyrin-containing compound metabolic process#GO:0006778;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;heterocycle biosynthetic process#GO:0018130;heme biosynthetic process#GO:0006783;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;pigment biosynthetic process#GO:0046148;aromatic compound biosynthetic process#GO:0019438;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;heme metabolic process#GO:0042168;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 hydrolase#PC00121 Heme biosynthesis#P02746>Uroporphyrinogen-III synthase#P02974 HUMAN|HGNC=31652|UniProtKB=Q9UD57 Q9UD57 NKX1-2 PTHR24340:SF17 HOMEOBOX PROTEIN NKX NK1 TRANSCRIPTION FACTOR-RELATED PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=3238|UniProtKB=P18146 P18146 EGR1 PTHR23235:SF42 KRUEPPEL-LIKE TRANSCRIPTION FACTOR EARLY GROWTH RESPONSE PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 CCKR signaling map#P06959>EGR1#P07192;Gonadotropin-releasing hormone receptor pathway#P06664>EGR1#G06887;Gonadotropin-releasing hormone receptor pathway#P06664>EGR1#G06672;Gonadotropin-releasing hormone receptor pathway#P06664>EGR1#P06837;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>EGR#P05931 HUMAN|HGNC=34496|UniProtKB=A6NCJ1 A6NCJ1 C19orf71 PTHR31254:SF1 HYPOTHETICAL PROTEIN LOC690617 HYPOTHETICAL PROTEIN LOC690617 HUMAN|HGNC=8194|UniProtKB=O43749 O43749 OR1F1 PTHR48001:SF98 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 1F1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=24282|UniProtKB=Q9Y388 Q9Y388 RBMX2 PTHR45880:SF4 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=19351|UniProtKB=Q9H694 Q9H694 BICC1 PTHR10627:SF69 SCP160 PROTEIN BICAUDAL C HOMOLOG 1 RNA metabolism protein#PC00031 HUMAN|HGNC=3827|UniProtKB=P25090 P25090 FPR2 PTHR24225:SF0 CHEMOTACTIC RECEPTOR N-FORMYL PEPTIDE RECEPTOR 2 complement binding#GO:0001848;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;immune response-regulating signaling pathway#GO:0002764;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;activation of immune response#GO:0002253;divalent inorganic cation homeostasis#GO:0072507;regulation of lipase activity#GO:0060191;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;immune response-activating signal transduction#GO:0002757;activation of phospholipase C activity#GO:0007202;regulation of immune system process#GO:0002682;regulation of hydrolase activity#GO:0051336;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;cellular cation homeostasis#GO:0030003;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;immune response#GO:0006955;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;regulation of immune response#GO:0050776;positive regulation of phospholipase activity#GO:0010518;positive regulation of immune system process#GO:0002684;homeostatic process#GO:0042592;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;immune system process#GO:0002376;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;immune response-activating cell surface receptor signaling pathway#GO:0002429;metal ion homeostasis#GO:0055065 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHKR#P00854 HUMAN|HGNC=10661|UniProtKB=P31431 P31431 SDC4 PTHR10915:SF3 SYNDECAN SYNDECAN-4 localization#GO:0051179;movement of cell or subcellular component#GO:0006928;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell migration#GO:0016477;locomotion#GO:0040011 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 transmembrane signal receptor#PC00197 HUMAN|HGNC=5797|UniProtKB=A0A075B6R9 A0A075B6R9 IGKV2D-24 PTHR23267:SF379 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 2-24-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=18028|UniProtKB=Q9NPF4 Q9NPF4 OSGEP PTHR11735:SF14 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE-RELATED protein-containing complex#GO:0032991;EKC/KEOPS complex#GO:0000408;intracellular#GO:0005622 RNA processing factor#PC00147 HUMAN|HGNC=20645|UniProtKB=Q9BWM5 Q9BWM5 ZNF416 PTHR24377:SF724 IP01015P-RELATED ZINC FINGER PROTEIN 416 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=28923|UniProtKB=Q8NCG7 Q8NCG7 DAGLB PTHR45792:SF2 DIACYLGLYCEROL LIPASE HOMOLOG-RELATED DIACYLGLYCEROL LIPASE-BETA cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;neurogenesis#GO:0022008;developmental process#GO:0032502;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;biosynthetic process#GO:0009058;nervous system development#GO:0007399;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of biological process#GO:0050789;system development#GO:0048731;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of neurotransmitter levels#GO:0001505;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;signaling#GO:0023052;metabolic process#GO:0008152 synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 lipase#PC00143 HUMAN|HGNC=2696|UniProtKB=Q9UJU6 Q9UJU6 DBNL PTHR10829:SF12 CORTACTIN AND DREBRIN DREBRIN-LIKE PROTEIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;regulation of dendrite development#GO:0050773;cell projection organization#GO:0030030;dendrite development#GO:0016358;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;dendritic spine organization#GO:0097061;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;positive regulation of cell development#GO:0010720;positive regulation of biological process#GO:0048518;positive regulation of axonogenesis#GO:0050772;protein-containing complex subunit organization#GO:0043933;positive regulation of growth#GO:0045927;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular protein-containing complex assembly#GO:0034622;neuron projection extension#GO:1990138;regulation of multicellular organismal process#GO:0051239;regulation of dendritic spine development#GO:0060998;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron differentiation#GO:0045664;positive regulation of cellular process#GO:0048522;regulation of neuron projection development#GO:0010975;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;synapse organization#GO:0050808;axon development#GO:0061564;positive regulation of neurogenesis#GO:0050769;regulation of axonogenesis#GO:0050770;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;regulation of synapse structure or activity#GO:0050803;positive regulation of neuron projection development#GO:0010976;positive regulation of cell growth#GO:0030307;positive regulation of multicellular organismal process#GO:0051240;regulation of dendrite morphogenesis#GO:0048814;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;positive regulation of cell projection organization#GO:0031346;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;growth#GO:0040007;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;cell differentiation#GO:0030154;system development#GO:0048731;regulation of protein-containing complex assembly#GO:0043254;axon extension#GO:0048675;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;neuron differentiation#GO:0030182;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of protein polymerization#GO:0032271;cell part morphogenesis#GO:0032990;regulation of cell growth#GO:0001558;regulation of anatomical structure size#GO:0090066;positive regulation of neuron differentiation#GO:0045666;developmental cell growth#GO:0048588;developmental growth involved in morphogenesis#GO:0060560;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of cell differentiation#GO:0045597;regulation of cell development#GO:0060284;developmental growth#GO:0048589;regulation of actin filament length#GO:0030832;multicellular organism development#GO:0007275;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;cell growth#GO:0016049;dendrite morphogenesis#GO:0048813;positive regulation of developmental process#GO:0051094;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of supramolecular fiber organization#GO:1902903;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 supramolecular complex#GO:0099080;synapse#GO:0045202;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cortical actin cytoskeleton#GO:0030864;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;cortical cytoskeleton#GO:0030863;cell junction#GO:0030054;dendrite#GO:0030425;dendritic tree#GO:0097447;supramolecular fiber#GO:0099512;cell cortex#GO:0005938;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;synaptic membrane#GO:0097060;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;neuron projection#GO:0043005;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;site of polarized growth#GO:0030427 non-motor actin binding protein#PC00165 HUMAN|HGNC=16635|UniProtKB=P82673 P82673 MRPS35 PTHR13490:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 28S RIBOSOMAL PROTEIN S35, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202 HUMAN|HGNC=13043|UniProtKB=P17030 P17030 ZNF25 PTHR24381:SF62 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 25 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=15568|UniProtKB=Q9H299 Q9H299 SH3BGRL3 PTHR12232:SF3 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 3 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=26197|UniProtKB=Q8N6T0 Q8N6T0 TOP6BL PTHR14652:SF2 TYPE 2 DNA TOPOISOMERASE 6 SUBUNIT B-LIKE TYPE 2 DNA TOPOISOMERASE 6 SUBUNIT B-LIKE DNA metabolism protein#PC00009 HUMAN|HGNC=13044|UniProtKB=P15622 P15622 ZNF250 PTHR24377:SF112 IP01015P-RELATED ZINC FINGER PROTEIN 250 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=102|UniProtKB=Q9NRU3 Q9NRU3 CNNM1 PTHR12064:SF28 ANCIENT CONSERVED DOMAIN PROTEIN-RELATED METAL TRANSPORTER CNNM1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=11454|UniProtKB=P50226 P50226 SULT1A2 PTHR11783:SF297 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1A2 transferase#PC00220 HUMAN|HGNC=10616|UniProtKB=P55774 P55774 CCL18 PTHR12015:SF94 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 18 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=18455|UniProtKB=Q9HC23 Q9HC23 PROK2 PTHR18821:SF8 PROKINETICIN PROKINETICIN-2 peptide hormone#PC00179 HUMAN|HGNC=11846|UniProtKB=Q99442 Q99442 SEC62 PTHR12443:SF9 TRANSLOCATION PROTEIN SEC62 TRANSLOCATION PROTEIN SEC62 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;protein localization to endoplasmic reticulum#GO:0070972;transmembrane transport#GO:0055085;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular protein localization#GO:0034613;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein targeting#GO:0006605;nitrogen compound transport#GO:0071705;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;posttranslational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=9403|UniProtKB=P24723 P24723 PRKCH PTHR24356:SF192 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C ETA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;EGF receptor signaling pathway#P00018>PKC#P00565;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;VEGF signaling pathway#P00056>PKC#P01425;FGF signaling pathway#P00021>PKC#P00648;CCKR signaling map#P06959>PKCeta#P07068;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Apoptosis signaling pathway#P00006>PKCs#P00318 HUMAN|HGNC=10451|UniProtKB=P23921 P23921 RRM1 PTHR11573:SF6 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491;ATP binding#GO:0005524 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 reductase#PC00198 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921;De novo purine biosynthesis#P02738>GDP reductase#P02909 HUMAN|HGNC=19136|UniProtKB=Q64ET8 Q64ET8 FRG2 PTHR31883:SF7 PROTEIN FRG2-RELATED PROTEIN FRG2-RELATED HUMAN|HGNC=1737|UniProtKB=Q5VT25 Q5VT25 CDC42BPA PTHR22988:SF31 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE/THREONINE-PROTEIN KINASE MRCK ALPHA transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;actomyosin structure organization#GO:0031032;protein phosphorylation#GO:0006468;cellular component organization#GO:0016043;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;peptidyl-threonine phosphorylation#GO:0018107;organelle organization#GO:0006996;nitrogen compound metabolic process#GO:0006807;cytoskeleton organization#GO:0007010;phosphorylation#GO:0016310;actin cytoskeleton organization#GO:0030036;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;actomyosin#GO:0042641;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=24198|UniProtKB=P78358 P78358 CTAG1B PTHR31283:SF4 EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER CANCER/TESTIS ANTIGEN 1 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;tRNA threonylcarbamoyladenosine metabolic process#GO:0070525;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 protein-containing complex#GO:0032991;EKC/KEOPS complex#GO:0000408;intracellular#GO:0005622 HUMAN|HGNC=13505|UniProtKB=Q9HCX3 Q9HCX3 ZNF304 PTHR24377:SF681 IP01015P-RELATED ZINC FINGER PROTEIN 304 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=25194|UniProtKB=Q96B21 Q96B21 TMEM45B PTHR16007:SF59 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B HUMAN|HGNC=18128|UniProtKB=Q969S8 Q969S8 HDAC10 PTHR48252:SF32 HISTONE DEACETYLASE 2-RELATED POLYAMINE DEACETYLASE HDAC10 HUMAN|HGNC=23643|UniProtKB=Q8IVF6 Q8IVF6 ANKRD18A PTHR24147:SF22 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 18A HUMAN|HGNC=17032|UniProtKB=Q9Y279 Q9Y279 VSIG4 PTHR15466:SF2 V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 4 V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 4 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=6087|UniProtKB=Q14641 Q14641 INSL4 PTHR12004:SF3 RELAXIN EARLY PLACENTA INSULIN-LIKE PEPTIDE peptide hormone#PC00179 HUMAN|HGNC=7569|UniProtKB=P35749 P35749 MYH11 PTHR45615:SF23 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-11 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=14672|UniProtKB=Q9H981 Q9H981 ACTR8 PTHR11937:SF13 ACTIN ACTIN-RELATED PROTEIN 8 pyrophosphatase activity#GO:0016462;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;ATP-dependent chromatin remodeling#GO:0043044;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of nucleic acid-templated transcription#GO:1903506;cellular response to stress#GO:0033554;chromatin remodeling#GO:0006338;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;Ino80 complex#GO:0031011;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;DNA helicase complex#GO:0033202 actin and actin related protein#PC00039 HUMAN|HGNC=8676|UniProtKB=Q9H158 Q9H158 PCDHAC1 PTHR24028:SF153 CADHERIN-87A PROTOCADHERIN ALPHA-C1 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=6720|UniProtKB=P02788 P02788 LTF PTHR11485:SF55 TRANSFERRIN LACTOTRANSFERRIN response to external biotic stimulus#GO:0043207;metal ion transport#GO:0030001;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;localization#GO:0051179;defense response to bacterium#GO:0042742;antibacterial humoral response#GO:0019731;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;antimicrobial humoral response#GO:0019730;defense response to other organism#GO:0098542;establishment of localization#GO:0051234;response to other organism#GO:0051707;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;defense response#GO:0006952 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;early endosome#GO:0005769;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 HUMAN|HGNC=2295|UniProtKB=P00450 P00450 CP PTHR11709:SF226 MULTI-COPPER OXIDASE CERULOPLASMIN ferroxidase activity#GO:0004322;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;transport#GO:0006810;homeostatic process#GO:0042592;cation transport#GO:0006812;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;localization#GO:0051179;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;establishment of localization#GO:0051234;iron ion homeostasis#GO:0055072;biological regulation#GO:0065007;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;metal ion homeostasis#GO:0055065 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175 HUMAN|HGNC=16191|UniProtKB=Q8IVV8 Q8IVV8 NKAIN4 PTHR13084:SF5 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN 4 localization#GO:0051179;regulation of biological process#GO:0050789;sodium ion transport#GO:0006814;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;regulation of transport#GO:0051049;regulation of sodium ion transport#GO:0002028;establishment of localization#GO:0051234;regulation of metal ion transport#GO:0010959;ion transport#GO:0006811;transport#GO:0006810;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;regulation of localization#GO:0032879;cation transport#GO:0006812 HUMAN|HGNC=31973|UniProtKB=A8MQT2 A8MQT2 GOLGA8B PTHR10881:SF63 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8A-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=20096|UniProtKB=Q96BM1 Q96BM1 ANKRD9 PTHR24133:SF16 FAMILY NOT NAMED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 9 HUMAN|HGNC=9090|UniProtKB=Q14651 Q14651 PLS1 PTHR19961:SF27 FIMBRIN/PLASTIN PLASTIN-1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament bundle assembly#GO:0051017;actin filament organization#GO:0007015;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;actin filament bundle organization#GO:0061572;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;actin filament bundle#GO:0032432;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 HUMAN|HGNC=20234|UniProtKB=Q9UI08 Q9UI08 EVL PTHR11202:SF4 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER ENA/VASP-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 scaffold/adaptor protein#PC00226 Cytoskeletal regulation by Rho GTPase#P00016>Ena/VASP#P00516 HUMAN|HGNC=24529|UniProtKB=Q9Y2Y6 Q9Y2Y6 TMEM98 PTHR32510:SF4 TRANSMEMBRANE PROTEIN 98 TRANSMEMBRANE PROTEIN 98 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=16698|UniProtKB=Q96PQ0 Q96PQ0 SORCS2 PTHR12106:SF9 SORTILIN RELATED VPS10 DOMAIN-CONTAINING RECEPTOR SORCS2 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810 cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;integral component of membrane#GO:0016021;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=4376|UniProtKB=P36959 P36959 GMPR PTHR43170:SF3 GMP REDUCTASE GMP REDUCTASE 1 reductase#PC00198 HUMAN|HGNC=1082|UniProtKB=Q12981 Q12981 BNIP1 PTHR12825:SF0 BNIP1-RELATED VESICLE TRANSPORT PROTEIN SEC20 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=11572|UniProtKB=P26639 P26639 TARS1 PTHR11451:SF36 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE 1, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=11824|UniProtKB=Q9BSI4 Q9BSI4 TINF2 PTHR15512:SF0 TERF1-INTERACTING NUCLEAR FACTOR 2 TERF1-INTERACTING NUCLEAR FACTOR 2 telomeric DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 telomere maintenance via telomere lengthening#GO:0010833;cellular aromatic compound metabolic process#GO:0006725;telomere organization#GO:0032200;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of DNA metabolic process#GO:0051052;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance#GO:0000723;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;telomere capping#GO:0016233;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;regulation of telomere maintenance via telomere lengthening#GO:1904356;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;chromosome organization#GO:0051276;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;DNA metabolic process#GO:0006259;regulation of cellular metabolic process#GO:0031323 nuclear telomere cap complex#GO:0000783;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781;protein-DNA complex#GO:0032993;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14025|UniProtKB=Q9GZV3 Q9GZV3 SLC5A7 PTHR45897:SF2 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH AFFINITY CHOLINE TRANSPORTER 1 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;organic cation transmembrane transporter activity#GO:0015101;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 ion transport#GO:0006811;transport#GO:0006810;trans-synaptic signaling#GO:0099537;nitrogen compound transport#GO:0071705;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;synaptic transmission, cholinergic#GO:0007271;cation transport#GO:0006812;biosynthetic process#GO:0009058;cellular process#GO:0009987;localization#GO:0051179;organic substance transport#GO:0071702;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;nitrogen compound metabolic process#GO:0006807;choline transport#GO:0015871;regulation of neurotransmitter levels#GO:0001505;organic cation transport#GO:0015695;biological regulation#GO:0065007;synaptic signaling#GO:0099536;neuromuscular synaptic transmission#GO:0007274;cell-cell signaling#GO:0007267;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;cell body#GO:0044297;neuron projection#GO:0043005;perikaryon#GO:0043204;plasma membrane region#GO:0098590;cell projection#GO:0042995;plasma membrane#GO:0005886 transporter#PC00227 Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072 HUMAN|HGNC=12756|UniProtKB=P57081 P57081 WDR4 PTHR16288:SF0 WD40 REPEAT PROTEIN 4 TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT WDR4 tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=6909|UniProtKB=O15232 O15232 MATN3 PTHR24020:SF12 COLLAGEN ALPHA MATRILIN-3 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=4558|UniProtKB=P59796 P59796 GPX6 PTHR11592:SF15 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE 6 oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 peroxidase#PC00180 HUMAN|HGNC=21247|UniProtKB=Q7Z4R8 Q7Z4R8 C6orf120 PTHR31703:SF2 UPF0669 PROTEIN C6ORF120 UPF0669 PROTEIN C6ORF120 HUMAN|HGNC=21488|UniProtKB=Q5EE01 Q5EE01 CENPW PTHR34832:SF1 CENTROMERE PROTEIN W CENTROMERE PROTEIN W protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;kinetochore organization#GO:0051383;nuclear division#GO:0000280;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;chromosome organization#GO:0051276;spindle assembly#GO:0051225;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;kinetochore assembly#GO:0051382;protein-containing complex subunit organization#GO:0043933 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;chromosomal region#GO:0098687 HUMAN|HGNC=15946|UniProtKB=Q8IWN7 Q8IWN7 RP1L1 PTHR23005:SF3 RETINITIS PIGMENTOSA 1 PROTEIN RETINITIS PIGMENTOSA 1-LIKE 1 PROTEIN microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;sensory system development#GO:0048880;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;anatomical structure development#GO:0048856;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;sensory organ development#GO:0007423;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;animal organ development#GO:0048513;developmental process#GO:0032502;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;cell differentiation#GO:0030154;system development#GO:0048731;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;retina development in camera-type eye#GO:0060041;cytoskeleton-dependent intracellular transport#GO:0030705;neuron differentiation#GO:0030182;protein localization to organelle#GO:0033365;visual system development#GO:0150063;vesicle localization#GO:0051648;multicellular organism development#GO:0007275;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cell development#GO:0048468;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;eye development#GO:0001654;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;camera-type eye development#GO:0043010;generation of neurons#GO:0048699 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=17010|UniProtKB=O15504 O15504 NUP42 PTHR46527:SF1 NUCLEOPORIN-LIKE PROTEIN 2 NUCLEOPORIN NUP42 HUMAN|HGNC=2910|UniProtKB=Q9NR61 Q9NR61 DLL4 PTHR24044:SF320 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN 4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of Notch signaling pathway#GO:0045746;regulation of Notch signaling pathway#GO:0008593;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;Notch signaling pathway#GO:0007219 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 HUMAN|HGNC=11160|UniProtKB=P62318 P62318 SNRPD3 PTHR23338:SF17 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D3 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;mRNA metabolic process#GO:0016071;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;cytoplasm#GO:0005737;SMN-Sm protein complex#GO:0034719;SMN complex#GO:0032797;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;spliceosomal tri-snRNP complex#GO:0097526;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114;U12-type spliceosomal complex#GO:0005689 RNA splicing factor#PC00148 HUMAN|HGNC=21234|UniProtKB=A0A3B3IU46 A0A3B3IU46 RAMACL PTHR48168:SF1 RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED RNA GUANINE-7 METHYLTRANSFERASE-ACTIVATING SUBUNIT-LIKE (PSEUDOGENE)-RELATED HUMAN|HGNC=34517|UniProtKB=A6NCQ9 A6NCQ9 RNF222 PTHR47095:SF1 RING FINGER PROTEIN 222 RING FINGER PROTEIN 222 HUMAN|HGNC=21658|UniProtKB=Q8NEE6 Q8NEE6 FBXL13 PTHR13318:SF215 UNCHARACTERIZED DYNEIN REGULATORY COMPLEX SUBUNIT 6 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;cellular protein catabolic process#GO:0044257;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 SCF ubiquitin ligase complex#GO:0019005;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 HUMAN|HGNC=24762|UniProtKB=P61129 P61129 ZC3H6 PTHR13119:SF22 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 6 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244 HUMAN|HGNC=16915|UniProtKB=O00165 O00165 HAX1 PTHR14938:SF2 HCLS1-ASSOCIATED PROTEIN X-1 HCLS1-ASSOCIATED PROTEIN X-1 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;negative regulation of programmed cell death#GO:0043069;supramolecular fiber organization#GO:0097435;apoptotic process#GO:0006915;cell death#GO:0008219;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of programmed cell death#GO:0043067;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of apoptotic process#GO:0042981;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;negative regulation of apoptotic process#GO:0043066;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 sarcoplasmic reticulum#GO:0016529;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;vacuole#GO:0005773;cell periphery#GO:0071944;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;clathrin-coated vesicle#GO:0030136;actin cytoskeleton#GO:0015629;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 HUMAN|HGNC=2431|UniProtKB=P55060 P55060 CSE1L PTHR10997:SF8 IMPORTIN-7, 8, 11 EXPORTIN-2 transporter activity#GO:0005215 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein export from nucleus#GO:0006611;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=19102|UniProtKB=O95786 O95786 DDX58 PTHR14074:SF16 HELICASE WITH DEATH DOMAIN-RELATED ANTIVIRAL INNATE IMMUNE RESPONSE RECEPTOR RIG-I cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=11194|UniProtKB=P35713 P35713 SOX18 PTHR10270:SF204 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-18 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;circulatory system development#GO:0072359;positive regulation of transcription, DNA-templated#GO:0045893;blood vessel morphogenesis#GO:0048514;macromolecule metabolic process#GO:0043170;tube development#GO:0035295;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;angiogenesis#GO:0001525;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;blood vessel development#GO:0001568;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HMG box transcription factor#PC00024 HUMAN|HGNC=7135|UniProtKB=P51825 P51825 AFF1 PTHR10528:SF6 AF4/FMR2 FAMILY MEMBER AF4/FMR2 FAMILY MEMBER 1 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023 DNA-binding transcription factor#PC00218 HUMAN|HGNC=16744|UniProtKB=Q9ULV3 Q9ULV3 CIZ1 PTHR15491:SF9 FAMILY NOT NAMED CIP1-INTERACTING ZINC FINGER PROTEIN HUMAN|HGNC=3518|UniProtKB=O43909 O43909 EXTL3 PTHR11062:SF73 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-LIKE 3 transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=11014|UniProtKB=Q99726 Q99726 SLC30A3 PTHR11562:SF30 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER ZINC TRANSPORTER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;transition metal ion transport#GO:0000041;cellular transition metal ion homeostasis#GO:0046916;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;response to inorganic substance#GO:0010035;transmembrane transport#GO:0055085;transition metal ion homeostasis#GO:0055076;ion transport#GO:0006811;homeostatic process#GO:0042592;response to metal ion#GO:0010038;cation homeostasis#GO:0055080;regulation of cellular localization#GO:0060341;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=18717|UniProtKB=P08910 P08910 ABHD2 PTHR10794:SF45 ABHYDROLASE DOMAIN-CONTAINING PROTEIN MONOACYLGLYCEROL LIPASE ABHD2 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;acylglycerol lipase activity#GO:0047372;catalytic activity#GO:0003824 male gamete generation#GO:0048232;neutral lipid catabolic process#GO:0046461;lipid catabolic process#GO:0016042;lipid biosynthetic process#GO:0008610;acylglycerol metabolic process#GO:0006639;hormone-mediated signaling pathway#GO:0009755;carboxylic acid biosynthetic process#GO:0046394;regulation of biological process#GO:0050789;neutral lipid metabolic process#GO:0006638;cellular response to hormone stimulus#GO:0032870;spermatogenesis#GO:0007283;reproductive process#GO:0022414;carboxylic acid catabolic process#GO:0046395;multi-organism reproductive process#GO:0044703;cellular lipid catabolic process#GO:0044242;multicellular organismal reproductive process#GO:0048609;organic substance metabolic process#GO:0071704;germ cell development#GO:0007281;sperm capacitation#GO:0048240;organic acid biosynthetic process#GO:0016053;cellular developmental process#GO:0048869;oxoacid metabolic process#GO:0043436;gamete generation#GO:0007276;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cell communication#GO:0007154;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;lipid metabolic process#GO:0006629;response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;cellular process involved in reproduction in multicellular organism#GO:0022412;cellular response to steroid hormone stimulus#GO:0071383;developmental process#GO:0032502;response to lipid#GO:0033993;spermatid differentiation#GO:0048515;biosynthetic process#GO:0009058;cellular response to lipid#GO:0071396;acylglycerol catabolic process#GO:0046464;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;glycerolipid metabolic process#GO:0046486;cellular response to organic cyclic compound#GO:0071407;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;signaling#GO:0023052;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;fatty acid biosynthetic process#GO:0006633;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;multicellular organism reproduction#GO:0032504;cellular biosynthetic process#GO:0044249;steroid hormone mediated signaling pathway#GO:0043401;glycerolipid catabolic process#GO:0046503;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;multi-organism process#GO:0051704;fatty acid catabolic process#GO:0009062;cell development#GO:0048468;spermatid development#GO:0007286;response to stimulus#GO:0050896;fatty acid metabolic process#GO:0006631;response to hormone#GO:0009725;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;response to steroid hormone#GO:0048545 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;cytoplasmic microtubule#GO:0005881;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;axonemal outer doublet#GO:0097545;motile cilium#GO:0031514;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;C2 axonemal microtubule#GO:1990720;plasma membrane region#GO:0098590;B axonemal microtubule#GO:0097650;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;C1 axonemal microtubule#GO:1990719;inner dynein arm#GO:0036156;catalytic complex#GO:1902494;A axonemal microtubule#GO:0097649;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;axonemal central pair#GO:0097540;sperm flagellum#GO:0036126;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;axonemal dynein complex#GO:0005858;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;9+2 motile cilium#GO:0097729;axonemal central apparatus#GO:1990716;plasma membrane bounded cell projection cytoplasm#GO:0032838;ciliary plasm#GO:0097014;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;axonemal microtubule#GO:0005879 serine protease#PC00203 HUMAN|HGNC=7391|UniProtKB=P28360 P28360 MSX1 PTHR24338:SF8 HOMEOBOX PROTEIN MSX HOMEOBOX PROTEIN MSX-1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 multicellular organismal process#GO:0032501;embryo development#GO:0009790;anatomical structure morphogenesis#GO:0009653;embryonic morphogenesis#GO:0048598;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 HUMAN|HGNC=8021|UniProtKB=P21589 P21589 NT5E PTHR11575:SF24 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE phosphodiesterase#PC00185 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 HUMAN|HGNC=17851|UniProtKB=Q9Y3B8 Q9Y3B8 REXO2 PTHR11046:SF0 OLIGORIBONUCLEASE, MITOCHONDRIAL OLIGORIBONUCLEASE, MITOCHONDRIAL HUMAN|HGNC=8759|UniProtKB=P20941 P20941 PDC PTHR46052:SF3 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Phosducin#P00758 HUMAN|HGNC=17997|UniProtKB=Q9H9S5 Q9H9S5 FKRP PTHR13627:SF31 FUKUTIN RELATED PROTEIN FUKUTIN-RELATED PROTEIN HUMAN|HGNC=26504|UniProtKB=Q96MI9 Q96MI9 AGBL1 PTHR12756:SF5 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 4 C-terminal protein amino acid modification#GO:0018410;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;post-translational protein modification#GO:0043687;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 metalloprotease#PC00153 HUMAN|HGNC=2546|UniProtKB=P56202 P56202 CTSW PTHR12411:SF101 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN W cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197 macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=11847|UniProtKB=Q15399 Q15399 TLR1 PTHR24365:SF261 TOLL-LIKE RECEPTOR TOLL-LIKE RECEPTOR 1 signaling receptor activity#GO:0038023;binding#GO:0005488;amide binding#GO:0033218;peptide binding#GO:0042277;protein binding#GO:0005515;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;signaling receptor binding#GO:0005102 response to organic substance#GO:0010033;response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;toll-like receptor signaling pathway#GO:0002224;cell communication#GO:0007154;pattern recognition receptor signaling pathway#GO:0002221;cellular process#GO:0009987;inflammatory response#GO:0006954;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;response to other organism#GO:0051707;biological regulation#GO:0065007;response to molecule of bacterial origin#GO:0002237;defense response#GO:0006952;signaling#GO:0023052 receptor complex#GO:0043235;membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 Toll receptor signaling pathway#P00054>TLR1,2,6#P01380;Toll receptor signaling pathway#P00054>TLR#P01346 HUMAN|HGNC=12500|UniProtKB=O95155 O95155 UBE4B PTHR13931:SF2 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 B ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;cellular protein modification process#GO:0006464;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=30339|UniProtKB=O15034 O15034 RIMBP2 PTHR14234:SF18 RIM BINDING PROTEIN-RELATED RIMS-BINDING PROTEIN 2 chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;neuromuscular synaptic transmission#GO:0007274;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 HUMAN|HGNC=21872|UniProtKB=Q9NUV9 Q9NUV9 GIMAP4 PTHR10903:SF62 GTPASE, IMAP FAMILY MEMBER-RELATED GTPASE IMAP FAMILY MEMBER 4 small GTPase#PC00208 HUMAN|HGNC=13026|UniProtKB=Q9UNY5 Q9UNY5 ZNF232 PTHR23226:SF54 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 232 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=17586|UniProtKB=Q9NZJ7 Q9NZJ7 MTCH1 PTHR10780:SF3 MITOCHONDRIAL CARRIER HOMOLOG MITOCHONDRIAL CARRIER HOMOLOG 1 regulation of biological process#GO:0050789;positive regulation of apoptotic process#GO:0043065;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;regulation of cell death#GO:0010941;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cell death#GO:0010942;regulation of programmed cell death#GO:0043067;positive regulation of cellular process#GO:0048522 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 mitochondrial carrier protein#PC00158 HUMAN|HGNC=29543|UniProtKB=B1AK76 B1AK76 SNURFL PTHR14508:SF2 SNRPN UPSTREAM READING FRAME PROTEIN, SNURF SNRPN UPSTREAM READING FRAME PROTEIN-RELATED membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;nuclear speck#GO:0016607;cellular anatomical entity#GO:0110165;nuclear body#GO:0016604;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=29131|UniProtKB=Q8IWE5 Q8IWE5 PLEKHM2 PTHR46556:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cellular localization#GO:0051641;organelle localization#GO:0051640;Golgi organization#GO:0007030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;localization#GO:0051179;lysosome localization#GO:0032418;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=10886|UniProtKB=Q8IXJ6 Q8IXJ6 SIRT2 PTHR48252:SF46 HISTONE DEACETYLASE 2-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2 HUMAN|HGNC=26295|UniProtKB=Q68D86 Q68D86 CCDC102B PTHR46292:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 102A COILED-COIL DOMAIN-CONTAINING PROTEIN 102B HUMAN|HGNC=8165|UniProtKB=Q96KK4 Q96KK4 OR10C1 PTHR26453:SF669 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10C1 transmembrane signal receptor#PC00197 HUMAN|HGNC=13398|UniProtKB=Q15738 Q15738 NSDHL PTHR10366:SF242 NAD DEPENDENT EPIMERASE/DEHYDRATASE STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091 HUMAN|HGNC=4852|UniProtKB=Q13547 Q13547 HDAC1 PTHR48252:SF36 HISTONE DEACETYLASE 2-RELATED HISTONE DEACETYLASE 1 Wnt signaling pathway#P00057>Histone deacetylase#P01472;p53 pathway#P00059>HDAC1#P04612 HUMAN|HGNC=21050|UniProtKB=Q5VV42 Q5VV42 CDKAL1 PTHR11918:SF45 RADICAL SAM PROTEINS THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE HUMAN|HGNC=30579|UniProtKB=Q8WYL5 Q8WYL5 SSH1 PTHR45864:SF5 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT HOMOLOG 1 hydrolase activity, acting on ester bonds#GO:0016788;cytoskeletal protein binding#GO:0008092;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;actin binding#GO:0003779;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;negative regulation of organelle organization#GO:0010639;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;negative regulation of cellular component organization#GO:0051129;regulation of protein polymerization#GO:0032271;negative regulation of cellular process#GO:0048523;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;negative regulation of actin filament polymerization#GO:0030837;biological regulation#GO:0065007;protein polymerization#GO:0051258;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 protein phosphatase#PC00195 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 HUMAN|HGNC=28970|UniProtKB=Q14156 Q14156 EFR3A PTHR12444:SF1 UNCHARACTERIZED PROTEIN EFR3 HOMOLOG A protein localization to cell periphery#GO:1990778;localization#GO:0051179;protein localization to plasma membrane#GO:0072659;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to membrane#GO:0072657;cellular process#GO:0009987;protein localization#GO:0008104 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=24829|UniProtKB=Q86SM5 Q86SM5 MRGPRG PTHR11334:SF32 MAS-RELATED G-PROTEIN COUPLED RECEPTOR MAS-RELATED G-PROTEIN COUPLED RECEPTOR MEMBER G signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=13101|UniProtKB=P17029 P17029 ZKSCAN1 PTHR23226:SF94 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29947|UniProtKB=Q9UPV9 Q9UPV9 TRAK1 PTHR15751:SF11 TRAFFICKING KINESIN-BINDING PROTEIN TRAFFICKING KINESIN-BINDING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;signaling receptor binding#GO:0005102;binding#GO:0005488 vesicle transport along microtubule#GO:0047496;cellular localization#GO:0051641;neurogenesis#GO:0022008;organelle localization#GO:0051640;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;developmental process#GO:0032502;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;endosome to lysosome transport#GO:0008333;nervous system development#GO:0007399;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;system development#GO:0048731;cell differentiation#GO:0030154;axo-dendritic transport#GO:0008088;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;mitochondrion organization#GO:0007005;establishment of organelle localization#GO:0051656;cellular developmental process#GO:0048869;vesicle localization#GO:0051648;vacuolar transport#GO:0007034;multicellular organism development#GO:0007275;protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;transport along microtubule#GO:0010970;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitochondrion distribution#GO:0048311;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;vesicle cytoskeletal trafficking#GO:0099518 somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;dendrite#GO:0030425;cell periphery#GO:0071944;mitochondrion#GO:0005739;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=9179|UniProtKB=P54098 P54098 POLG PTHR10267:SF0 DNA POLYMERASE SUBUNIT GAMMA-1 DNA POLYMERASE SUBUNIT GAMMA-1 hydrolase activity, acting on ester bonds#GO:0016788;DNA-directed DNA polymerase activity#GO:0003887;nuclease activity#GO:0004518;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;DNA polymerase activity#GO:0034061 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;DNA biosynthetic process#GO:0071897;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-directed DNA polymerase#PC00018 HUMAN|HGNC=24119|UniProtKB=Q9BSW7 Q9BSW7 SYT17 PTHR10024:SF348 SYNAPTOTAGMIN SYNAPTOTAGMIN-17 cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;phosphatidylserine binding#GO:0001786;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;protein binding#GO:0005515;lipid binding#GO:0008289;clathrin binding#GO:0030276;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;SNARE binding#GO:0000149 organic hydroxy compound transport#GO:0015850;vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of signaling#GO:0023051;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cation transport#GO:0006812;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;signal release#GO:0023061;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;ion transport#GO:0006811;vesicle-mediated transport#GO:0016192;response to metal ion#GO:0010038;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;membrane fusion#GO:0061025;exocytosis#GO:0006887;response to chemical#GO:0042221;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of ion transport#GO:0043269;export from cell#GO:0140352 synapse#GO:0045202;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;axon#GO:0030424;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;neuron projection#GO:0043005;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cell projection#GO:0042995;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=3044|UniProtKB=O14972 O14972 VPS26C PTHR12233:SF2 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26C cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;amide transport#GO:0042886;localization#GO:0051179;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=3219|UniProtKB=O95967 O95967 EFEMP2 PTHR24034:SF96 EGF-LIKE DOMAIN-CONTAINING PROTEIN EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 2 extracellular matrix structural protein#PC00103 HUMAN|HGNC=30788|UniProtKB=Q9H808 Q9H808 TLE6 PTHR10814:SF2 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 6 repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein binding#GO:0005515;molecular function regulator#GO:0098772;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 HUMAN|HGNC=327|UniProtKB=O00116 O00116 AGPS PTHR46568:SF1 ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL HUMAN|HGNC=4693|UniProtKB=Q16774 Q16774 GUK1 PTHR23117:SF13 GUANYLATE KINASE-RELATED GUANYLATE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;kinase activity#GO:0016301 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 kinase#PC00137 De novo purine biosynthesis#P02738>Guanylate kinase#P02904 HUMAN|HGNC=35445|UniProtKB=A8MY62 A8MY62 LACTBL1 PTHR22935:SF95 PENICILLIN-BINDING PROTEIN BETA-LACTAMASE-LIKE 1-RELATED HUMAN|HGNC=31350|UniProtKB=Q9NWM3 Q9NWM3 CUEDC1 PTHR13467:SF3 CUE DOMAIN CONTAINING PROTEIN 1 CUE DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=5469|UniProtKB=P08833 P08833 IGFBP1 PTHR11551:SF6 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 1 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signaling#GO:0023052;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 PI3 kinase pathway#P00048>IGFBP1#G01543 HUMAN|HGNC=23305|UniProtKB=Q8WV37 Q8WV37 ZNF480 PTHR24377:SF187 IP01015P-RELATED ZINC FINGER PROTEIN 480 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=18785|UniProtKB=P56182 P56182 RRP1 PTHR13026:SF1 NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52 RIBOSOMAL RNA PROCESSING PROTEIN 1 HOMOLOG A cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=119|UniProtKB=Q15067 Q15067 ACOX1 PTHR10909:SF250 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 1 nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;regulation of biological quality#GO:0065008;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;oxoacid metabolic process#GO:0043436;homeostatic process#GO:0042592;cellular metabolic process#GO:0044237;lipid oxidation#GO:0034440;cellular process#GO:0009987;chemical homeostasis#GO:0048878;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;fatty acid metabolic process#GO:0006631;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;lipid homeostasis#GO:0055088;biological regulation#GO:0065007;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176 HUMAN|HGNC=2850|UniProtKB=Q9Y6T7 Q9Y6T7 DGKB PTHR11255:SF32 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;neutral lipid metabolic process#GO:0006638;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 kinase#PC00137 HUMAN|HGNC=28529|UniProtKB=Q6ZMJ4 Q6ZMJ4 IL34 PTHR28606:SF1 INTERLEUKIN-34 INTERLEUKIN-34 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 animal organ development#GO:0048513;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;positive regulation of cell population proliferation#GO:0008284;regulation of multicellular organismal development#GO:2000026;cell population proliferation#GO:0008283;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;system development#GO:0048731;regulation of hemopoiesis#GO:1903706;hemopoiesis#GO:0030097;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;regulation of cell population proliferation#GO:0042127;positive regulation of cell differentiation#GO:0045597;immune system development#GO:0002520;multicellular organism development#GO:0007275;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;immune system process#GO:0002376;leukocyte differentiation#GO:0002521;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of multicellular organismal process#GO:0051240 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 interleukin superfamily#PC00128 HUMAN|HGNC=21066|UniProtKB=Q9P0N9 Q9P0N9 TBC1D7 PTHR13530:SF3 TBC1 DOMAIN FAMILY MEMBER 7 TBC1 DOMAIN FAMILY MEMBER 7 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;positive regulation of GTPase activity#GO:0043547;positive regulation of catalytic activity#GO:0043085;regulation of GTPase activity#GO:0043087;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of hydrolase activity#GO:0051345;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 GTPase-activating protein#PC00257 HUMAN|HGNC=1171|UniProtKB=Q96EB1 Q96EB1 ELP4 PTHR12896:SF1 PAX6 NEIGHBOR PROTEIN PAXNEB ELONGATOR COMPLEX PROTEIN 4 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription elongation factor complex#GO:0008023 HUMAN|HGNC=12234|UniProtKB=A0A0J9YX75 A0A0J9YX75 TRBV6-9 PTHR23268:SF86 T-CELL RECEPTOR BETA CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=51677|UniProtKB=H7BZ55 H7BZ55 CROCC2 PTHR23159:SF16 CENTROSOMAL PROTEIN 2 CILIARY ROOTLET COILED-COIL PROTEIN 2-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=16485|UniProtKB=Q8NHY5 Q8NHY5 HUS1B PTHR12900:SF3 MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 CHECKPOINT PROTEIN HUS1B DNA repair#GO:0006281;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;reproductive process#GO:0022414;organic substance metabolic process#GO:0071704;nucleotide-excision repair#GO:0006289;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;regulation of cell cycle phase transition#GO:1901987;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;mitotic DNA integrity checkpoint#GO:0044774;cell cycle phase transition#GO:0044770;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;G2/M transition of mitotic cell cycle#GO:0000086;response to stress#GO:0006950;reproduction#GO:0000003;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;mitotic G2/M transition checkpoint#GO:0044818;cellular response to stress#GO:0033554;cell cycle G2/M phase transition#GO:0044839;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;double-strand break repair#GO:0006302;mitotic cell cycle phase transition#GO:0044772;telomere organization#GO:0032200;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;intra-S DNA damage checkpoint#GO:0031573;mitotic cell cycle process#GO:1903047;telomere maintenance#GO:0000723;mitotic DNA replication checkpoint#GO:0033314;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle phase transition#GO:1901988;mitotic DNA damage checkpoint#GO:0044773;homeostatic process#GO:0042592;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;DNA replication checkpoint#GO:0000076;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;intracellular organelle lumen#GO:0070013;condensed nuclear chromosome#GO:0000794;site of double-strand break#GO:0035861;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 HUMAN|HGNC=15572|UniProtKB=Q9BQQ7 Q9BQQ7 RTP3 PTHR14402:SF9 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 3 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;system process#GO:0003008;nitrogen compound transport#GO:0071705;detection of chemical stimulus#GO:0009593;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein insertion into membrane#GO:0051205;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;detection of stimulus#GO:0051606;nervous system process#GO:0050877;cellular component organization#GO:0016043;sensory perception of chemical stimulus#GO:0007606;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;sensory perception#GO:0007600 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=80|UniProtKB=P19801 P19801 AOC1 PTHR10638:SF3 COPPER AMINE OXIDASE AMILORIDE-SENSITIVE AMINE OXIDASE [COPPER-CONTAINING] cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 organonitrogen compound metabolic process#GO:1901564;response to stimulus#GO:0050896;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 oxidase#PC00175 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 HUMAN|HGNC=13404|UniProtKB=Q9P2E7 Q9P2E7 PCDH10 PTHR24028:SF0 CADHERIN-87A PROTOCADHERIN-10 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=10080|UniProtKB=Q15287 Q15287 RNPS1 PTHR15481:SF2 RIBONUCLEIC ACID BINDING PROTEIN S1 RNA-BINDING PROTEIN WITH SERINE-RICH DOMAIN 1 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=2175|UniProtKB=O94779 O94779 CNTN5 PTHR44170:SF17 PROTEIN SIDEKICK CONTACTIN-5 HUMAN|HGNC=24227|UniProtKB=Q9ULG6 Q9ULG6 CCPG1 PTHR28638:SF2 CELL CYCLE PROGRESSION PROTEIN 1 CELL CYCLE PROGRESSION PROTEIN 1 biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=8895|UniProtKB=P53609 P53609 PGGT1B PTHR11774:SF4 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein prenylation#GO:0018342;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 acyltransferase#PC00042 HUMAN|HGNC=18075|UniProtKB=Q9NZD4 Q9NZD4 AHSP PTHR15914:SF0 ALPHA-HEMOGLOBIN-STABILIZING PROTEIN ALPHA-HEMOGLOBIN-STABILIZING PROTEIN myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;immune system development#GO:0002520;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;regulation of protein stability#GO:0031647;homeostatic process#GO:0042592;cellular process#GO:0009987;protein stabilization#GO:0050821;erythrocyte differentiation#GO:0030218;system development#GO:0048731;immune system process#GO:0002376;cell differentiation#GO:0030154;regulation of biological quality#GO:0065008;protein folding#GO:0006457;anatomical structure development#GO:0048856;biological regulation#GO:0065007;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=44668|UniProtKB=H3BQB6 H3BQB6 STMND1 PTHR10104:SF20 STATHMIN STATHMIN DOMAIN-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 regulation of microtubule-based process#GO:0032886;neurogenesis#GO:0022008;cellular protein complex disassembly#GO:0043624;cell projection organization#GO:0030030;microtubule depolymerization#GO:0007019;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of cytoskeleton organization#GO:0051493;cellular component disassembly#GO:0022411;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;protein-containing complex subunit organization#GO:0043933;cellular developmental process#GO:0048869;protein-containing complex disassembly#GO:0032984;regulation of organelle organization#GO:0033043;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;protein depolymerization#GO:0051261;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 HUMAN|HGNC=3430|UniProtKB=P04626 P04626 ERBB2 PTHR24416:SF137 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell population proliferation#GO:0042127;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;basolateral plasma membrane#GO:0016323;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 EGF receptor signaling pathway#P00018>EGFR#P00542;Cadherin signaling pathway#P00012>EGFR#P00466 HUMAN|HGNC=862|UniProtKB=O95670 O95670 ATP6V1G2 PTHR12713:SF13 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G 2 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;proton-transporting two-sector ATPase complex#GO:0016469;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002 HUMAN|HGNC=17936|UniProtKB=Q9NZ53 Q9NZ53 PODXL2 PTHR15594:SF1 PODOCALYXIN-LIKE PROTEIN 2 PODOCALYXIN-LIKE PROTEIN 2 HUMAN|HGNC=24908|UniProtKB=Q5SWL8 Q5SWL8 PRAMEF19 PTHR14224:SF76 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 19 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=1043|UniProtKB=P02818 P02818 BGLAP PTHR14235:SF0 OSTEOCALCIN OSTEOCALCIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;structural molecule activity#GO:0005198;binding#GO:0005488 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;ossification#GO:0001503;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;skeletal system development#GO:0001501;cellular process#GO:0009987;bone development#GO:0060348 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=7622|UniProtKB=Q01538 Q01538 MYT1 PTHR10816:SF10 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 zinc finger transcription factor#PC00244 HUMAN|HGNC=7631|UniProtKB=P17050 P17050 NAGA PTHR11452:SF25 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-N-ACETYLGALACTOSAMINIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;lipid catabolic process#GO:0016042;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;sphingolipid metabolic process#GO:0006665;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;sphingolipid catabolic process#GO:0030149;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;carbohydrate metabolic process#GO:0005975;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 galactosidase#PC00104 HUMAN|HGNC=14035|UniProtKB=Q9BYC8 Q9BYC8 MRPL32 PTHR21026:SF2 39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosomal protein#PC00202 HUMAN|HGNC=19027|UniProtKB=Q8IWT6 Q8IWT6 LRRC8A PTHR45752:SF23 LEUCINE-RICH REPEAT-CONTAINING VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8A hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 scaffold/adaptor protein#PC00226 HUMAN|HGNC=51260|UniProtKB=P0DMV0 P0DMV0 CT45A7 PTHR12957:SF22 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED CANCER/TESTIS ANTIGEN FAMILY 45 MEMBER A1-RELATED cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 RNA helicase#PC00032 HUMAN|HGNC=25598|UniProtKB=Q9NV66 Q9NV66 TYW1 PTHR13930:SF0 S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED lyase#PC00144 HUMAN|HGNC=14890|UniProtKB=Q9BTF0 Q9BTF0 THUMPD2 PTHR14911:SF1 THUMP DOMAIN-CONTAINING THUMP DOMAIN-CONTAINING PROTEIN 2 tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 RNA methyltransferase#PC00033 HUMAN|HGNC=12027|UniProtKB=P0DTU3 P0DTU3 TRA PTHR19433:SF72 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA CHAIN MC.7.G5-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=26347|UniProtKB=B5ME19 B5ME19 EIF3CL PTHR13937:SF0 EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=25510|UniProtKB=Q9GZU3 Q9GZU3 TMEM39B PTHR12995:SF2 UNCHARACTERIZED TRANSMEMBRANE PROTEIN 39B cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=20091|UniProtKB=Q96M32 Q96M32 AK7 PTHR23359:SF105 NUCLEOTIDE KINASE ADENYLATE KINASE 7 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;adenylate kinase activity#GO:0004017;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;nucleoside diphosphate metabolic process#GO:0009132;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotide kinase#PC00172 HUMAN|HGNC=19017|UniProtKB=Q86XT4 Q86XT4 TRIM50 PTHR24103:SF326 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM50 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=23078|UniProtKB=Q9BQI9 Q9BQI9 NRIP2 PTHR12917:SF17 ASPARTYL PROTEASE DDI-RELATED NUCLEAR RECEPTOR-INTERACTING PROTEIN 2 aspartic protease#PC00053 HUMAN|HGNC=26910|UniProtKB=Q8N2I2 Q8N2I2 ZNF619 PTHR24381:SF138 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 619 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=17097|UniProtKB=Q13868 Q13868 EXOSC2 PTHR21321:SF4 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP4 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 negative regulation of gene expression#GO:0010629;tRNA metabolic process#GO:0006399;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;heterocycle catabolic process#GO:0046700;rRNA processing#GO:0006364;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;ncRNA metabolic process#GO:0034660;mRNA metabolic process#GO:0016071;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;rRNA metabolic process#GO:0016072;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;cellular nitrogen compound catabolic process#GO:0044270;mRNA 3'-end processing#GO:0031124;organic cyclic compound metabolic process#GO:1901360;mRNA catabolic process#GO:0006402;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;RNA catabolic process#GO:0006401;snRNA processing#GO:0016180;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;maturation of 5.8S rRNA#GO:0000460;metabolic process#GO:0008152;cleavage involved in rRNA processing#GO:0000469;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;RNA 3'-end processing#GO:0031123;intracellular mRNA localization#GO:0008298;mRNA polyadenylation#GO:0006378;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular process#GO:0009987;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;nucleic acid phosphodiester bond hydrolysis#GO:0090305;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;ribonucleoprotein complex biogenesis#GO:0022613;biological regulation#GO:0065007;mRNA processing#GO:0006397;organic cyclic compound catabolic process#GO:1901361;cellular macromolecule catabolic process#GO:0044265 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;exosome (RNase complex)#GO:0000178;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=16825|UniProtKB=Q96EF0 Q96EF0 MTMR8 PTHR10807:SF36 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 8 hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;phospholipid dephosphorylation#GO:0046839;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;negative regulation of metabolic process#GO:0009892;negative regulation of autophagy#GO:0010507;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=15749|UniProtKB=Q9NP55 Q9NP55 BPIFA1 PTHR47015:SF1 BPI FOLD-CONTAINING FAMILY A MEMBER 1 BPI FOLD-CONTAINING FAMILY A MEMBER 1 HUMAN|HGNC=8777|UniProtKB=O00408 O00408 PDE2A PTHR11347:SF102 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PDEASE DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;protein homodimerization activity#GO:0042803;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;identical protein binding#GO:0042802;protein binding#GO:0005515;3',5'-cyclic-AMP phosphodiesterase activity#GO:0004115;3',5'-cyclic-GMP phosphodiesterase activity#GO:0047555;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 positive regulation of gene expression#GO:0010628;heterocycle catabolic process#GO:0046700;cyclic nucleotide metabolic process#GO:0009187;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;regulation of mitochondrion organization#GO:0010821;purine ribonucleotide catabolic process#GO:0009154;regulation of signal transduction#GO:0009966;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;purine nucleotide metabolic process#GO:0006163;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;carbohydrate derivative metabolic process#GO:1901135;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cGMP-mediated signaling#GO:0019934;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;response to stimulus#GO:0050896;negative regulation of cAMP-mediated signaling#GO:0043951;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;cyclic-nucleotide-mediated signaling#GO:0019935;nucleobase-containing small molecule metabolic process#GO:0055086 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;perinuclear region of cytoplasm#GO:0048471;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial matrix#GO:0005759;plasma membrane region#GO:0098590;membrane-enclosed lumen#GO:0031974;envelope#GO:0031975;mitochondrial membrane#GO:0031966;organelle lumen#GO:0043233;nucleus#GO:0005634;cell junction#GO:0030054;intracellular organelle lumen#GO:0070013;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;cell periphery#GO:0071944;membrane#GO:0016020;synaptic membrane#GO:0097060;whole membrane#GO:0098805;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;plasma membrane#GO:0005886 phosphodiesterase#PC00185 HUMAN|HGNC=15218|UniProtKB=Q8NGJ2 Q8NGJ2 OR52H1 PTHR26450:SF123 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52H1 transmembrane signal receptor#PC00197 HUMAN|HGNC=23720|UniProtKB=Q70SY1 Q70SY1 CREB3L2 PTHR46004:SF2 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 HUMAN|HGNC=6600|UniProtKB=P49916 P49916 LIG3 PTHR45674:SF9 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 3 DNA ligase#PC00012 HUMAN|HGNC=3097|UniProtKB=O75923 O75923 DYSF PTHR12546:SF44 FER-1-LIKE DYSFERLIN cation binding#GO:0043169;calcium-dependent phospholipid binding#GO:0005544;binding#GO:0005488;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543 vesicle fusion#GO:0006906;negative regulation of biological process#GO:0048519;muscle cell differentiation#GO:0042692;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;plasma membrane organization#GO:0007009;transport#GO:0006810;developmental process#GO:0032502;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;wound healing#GO:0042060;regulation of vesicle-mediated transport#GO:0060627;muscle structure development#GO:0061061;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transport#GO:0051049;establishment of localization#GO:0051234;vesicle organization#GO:0016050;negative regulation of cellular process#GO:0048523;immune effector process#GO:0002252;leukocyte activation#GO:0045321;organelle fusion#GO:0048284;cellular developmental process#GO:0048869;immune response#GO:0006955;phagocytosis#GO:0006909;vesicle-mediated transport#GO:0016192;negative regulation of transport#GO:0051051;cellular component organization#GO:0016043;cellular process#GO:0009987;cell activation involved in immune response#GO:0002263;localization#GO:0051179;cell activation#GO:0001775;muscle cell development#GO:0055001;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;immune system process#GO:0002376;response to stimulus#GO:0050896;membrane fusion#GO:0061025;response to wounding#GO:0009611;response to stress#GO:0006950;leukocyte activation involved in immune response#GO:0002366;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;sarcolemma#GO:0042383 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=17075|UniProtKB=Q9NYJ8 Q9NYJ8 TAB2 PTHR46253:SF2 TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 2 protein binding#GO:0005515;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;positive regulation of protein modification process#GO:0031401;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;positive regulation of phosphate metabolic process#GO:0045937;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 p38 MAPK pathway#P05918>TAB2#P06033 HUMAN|HGNC=27014|UniProtKB=Q8N1E2 Q8N1E2 LYG1 PTHR31698:SF5 LYSOZYME G FAMILY MEMBER LYSOZYME G-LIKE PROTEIN 1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 response to external biotic stimulus#GO:0043207;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to bacterium#GO:0009617;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response#GO:0006952;defense response to Gram-positive bacterium#GO:0050830 cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=8971|UniProtKB=O00443 O00443 PIK3C2A PTHR10048:SF28 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;phosphatidylinositol-mediated signaling#GO:0048015;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;phosphatidylinositol 3-kinase signaling#GO:0014065;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;inositol lipid-mediated signaling#GO:0048017;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477;locomotion#GO:0040011;phosphatidylinositol phosphorylation#GO:0046854 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;Angiogenesis#P00005>PI3K#P00236;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 HUMAN|HGNC=32207|UniProtKB=Q6ZN17 Q6ZN17 LIN28B PTHR46109:SF3 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG B RNA metabolism protein#PC00031 HUMAN|HGNC=18229|UniProtKB=Q96D21 Q96D21 RASD2 PTHR46149:SF1 MIP08469P GTP-BINDING PROTEIN RHES HUMAN|HGNC=26048|UniProtKB=Q75QN2 Q75QN2 INTS8 PTHR13350:SF1 UNCHARACTERIZED INTEGRATOR COMPLEX SUBUNIT 8 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 HUMAN|HGNC=32783|UniProtKB=O43361 O43361 ZNF749 PTHR24381:SF5 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 749 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4075|UniProtKB=P14867 P14867 GABRA1 PTHR18945:SF514 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;chloride channel activity#GO:0005254;ion channel activity#GO:0005216;binding#GO:0005488;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;neurotransmitter receptor activity#GO:0030594;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;molecular transducer activity#GO:0060089;inorganic anion transmembrane transporter activity#GO:0015103;ligand-gated channel activity#GO:0022834 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;transmembrane transport#GO:0055085;ion transport#GO:0006811;system process#GO:0003008;transport#GO:0006810;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;nervous system process#GO:0050877;cell communication#GO:0007154;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;localization#GO:0051179;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;signaling#GO:0023052;cell-cell signaling#GO:0007267 synapse#GO:0045202;cell junction#GO:0030054;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cell leading edge#GO:0031252;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=15857|UniProtKB=Q9NWU2 Q9NWU2 GID8 PTHR12864:SF3 RAN BINDING PROTEIN 9-RELATED GLUCOSE-INDUCED DEGRADATION PROTEIN 8 HOMOLOG macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=30235|UniProtKB=Q9UHF3 Q9UHF3 NAT8B PTHR13947:SF14 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE 8-RELATED transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 HUMAN|HGNC=18891|UniProtKB=Q9BYR9 Q9BYR9 KRTAP2-4 PTHR23262:SF199 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 2-2-RELATED HUMAN|HGNC=21549|UniProtKB=Q5T6X4 Q5T6X4 FAM162B PTHR13674:SF3 GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN PROTEIN FAM162B HUMAN|HGNC=21367|UniProtKB=Q8N884 Q8N884 CGAS PTHR10656:SF35 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE nucleic acid binding#GO:0003676;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;DNA binding#GO:0003677;transferase activity, transferring phosphorus-containing groups#GO:0016772;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 DNA repair#GO:0006281;response to external biotic stimulus#GO:0043207;positive regulation of gene expression#GO:0010628;negative regulation of response to DNA damage stimulus#GO:2001021;regulation of double-strand break repair#GO:2000779;regulation of response to DNA damage stimulus#GO:2001020;activation of immune response#GO:0002253;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;gene expression#GO:0010467;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;positive regulation of immune response#GO:0050778;regulation of cellular response to stress#GO:0080135;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;recombinational repair#GO:0000725;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;positive regulation of cytokine production#GO:0001819;intracellular signal transduction#GO:0035556;defense response to virus#GO:0051607;positive regulation of signaling#GO:0023056;defense response#GO:0006952;negative regulation of DNA metabolic process#GO:0051053;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;double-strand break repair via homologous recombination#GO:0000724;positive regulation of macromolecule metabolic process#GO:0010604;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of defense response#GO:0031347;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of double-strand break repair via homologous recombination#GO:2000042;positive regulation of defense response#GO:0031349;cellular response to stress#GO:0033554;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;cellular aromatic compound metabolic process#GO:0006725;response to virus#GO:0009615;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;second-messenger-mediated signaling#GO:0019932;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;negative regulation of DNA repair#GO:0045738;regulation of signaling#GO:0023051;regulation of DNA repair#GO:0006282;cellular response to nitrogen compound#GO:1901699;regulation of double-strand break repair via homologous recombination#GO:0010569;cytokine production#GO:0001816;positive regulation of response to stimulus#GO:0048584;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;cellular response to organic cyclic compound#GO:0071407;regulation of immune system process#GO:0002682;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;negative regulation of DNA recombination#GO:0045910;immune effector process#GO:0002252;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;immune response#GO:0006955;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cGMP-mediated signaling#GO:0019934;cellular process#GO:0009987;regulation of response to biotic stimulus#GO:0002831;regulation of innate immune response#GO:0045088;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of immune effector process#GO:0002697;response to external stimulus#GO:0009605;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;activation of innate immune response#GO:0002218;response to chemical#GO:0042221;response to other organism#GO:0051707;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of double-strand break repair#GO:2000780;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of DNA recombination#GO:0000018;positive regulation of response to biotic stimulus#GO:0002833;cyclic-nucleotide-mediated signaling#GO:0019935;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;site of double-strand break#GO:0035861;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=1058|UniProtKB=P54132 P54132 BLM PTHR13710:SF105 DNA HELICASE RECQ FAMILY MEMBER BLOOM SYNDROME PROTEIN pyrophosphatase activity#GO:0016462;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;DNA geometric change#GO:0032392;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;DNA duplex unwinding#GO:0032508;cellular response to stress#GO:0033554;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA helicase#PC00011 HUMAN|HGNC=10755|UniProtKB=O75920 O75920 SERF1B PTHR13596:SF1 SMALL EDRK-RICH FACTOR 1 SMALL EDRK-RICH FACTOR 1 HUMAN|HGNC=24578|UniProtKB=Q5TDH0 Q5TDH0 DDI2 PTHR12917:SF13 ASPARTYL PROTEASE DDI-RELATED PROTEIN DDI1 HOMOLOG 2 aspartic protease#PC00053 HUMAN|HGNC=11006|UniProtKB=P11168 P11168 SLC2A2 PTHR23503:SF27 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 2 HUMAN|HGNC=28533|UniProtKB=Q8N5S1 Q8N5S1 SLC25A41 PTHR24089:SF181 SOLUTE CARRIER FAMILY 25 SOLUTE CARRIER FAMILY 25 MEMBER 41 carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;ATP transmembrane transporter activity#GO:0005347;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;ion transmembrane transporter activity#GO:0015075;nucleotide transmembrane transporter activity#GO:0015215;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 mitochondrial carrier protein#PC00158 HUMAN|HGNC=11501|UniProtKB=O43761 O43761 SYNGR3 PTHR10838:SF8 SYNAPTOGYRIN SYNAPTOGYRIN-3 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;vesicle membrane#GO:0012506;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;neuromuscular junction#GO:0031594;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=280|UniProtKB=P25100 P25100 ADRA1D PTHR24248:SF14 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1D ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of lipase activity#GO:0060191;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular cation homeostasis#GO:0030003;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 HUMAN|HGNC=32312|UniProtKB=Q7L8S5 Q7L8S5 OTUD6A PTHR12419:SF13 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 6A hydrolase activity#GO:0016787;thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cysteine protease#PC00081 HUMAN|HGNC=8805|UniProtKB=Q15198 Q15198 PDGFRL PTHR15360:SF1 PLATELET-DERIVED GROWTH FACTOR RECEPTOR LIKE PLATELET-DERIVED GROWTH FACTOR RECEPTOR-LIKE PROTEIN tyrosine protein kinase receptor#PC00233 PDGF signaling pathway#P00047>PDGF receptor A#P01158;PDGF signaling pathway#P00047>PDGF receptor B#P01156 HUMAN|HGNC=12469|UniProtKB=P22314 P22314 UBA1 PTHR10953:SF155 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 1 ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490;Ubiquitin proteasome pathway#P00060>E1#P01492 HUMAN|HGNC=14679|UniProtKB=Q969I6 Q969I6 SLC38A4 PTHR22950:SF222 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 amino acid transporter#PC00046 HUMAN|HGNC=30636|UniProtKB=Q96A04 Q96A04 TSACC PTHR37368:SF1 TSSK6-ACTIVATING CO-CHAPERONE PROTEIN TSSK6-ACTIVATING CO-CHAPERONE PROTEIN protein binding#GO:0005515;binding#GO:0005488;chaperone binding#GO:0051087 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=8824|UniProtKB=P36955 P36955 SERPINF1 PTHR11461:SF84 SERINE PROTEASE INHIBITOR, SERPIN PIGMENT EPITHELIUM-DERIVED FACTOR serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=14352|UniProtKB=Q9H1Z4 Q9H1Z4 WDR13 PTHR22838:SF4 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 13 HUMAN|HGNC=14897|UniProtKB=Q96DU7 Q96DU7 ITPKC PTHR12400:SF26 INOSITOL POLYPHOSPHATE KINASE INOSITOL-TRISPHOSPHATE 3-KINASE C transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 HUMAN|HGNC=13017|UniProtKB=Q9NZL3 Q9NZL3 ZNF224 PTHR24376:SF129 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 224-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=779|UniProtKB=Q86WG3 Q86WG3 ATCAY PTHR12112:SF9 BNIP - RELATED CAYTAXIN pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;organic substance catabolic process#GO:1901575;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;phosphorus metabolic process#GO:0006793;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=417|UniProtKB=P05062 P05062 ALDOB PTHR11627:SF2 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE B lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;fructose-bisphosphate aldolase activity#GO:0004332 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;purine nucleoside diphosphate metabolic process#GO:0009135;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ATP generation from ADP#GO:0006757;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;carbohydrate catabolic process#GO:0016052;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;carbohydrate metabolic process#GO:0005975;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;purine ribonucleoside diphosphate metabolic process#GO:0009179;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;organonitrogen compound metabolic process#GO:1901564;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aldolase#PC00044 Glycolysis#P00024>Aldolase#P00679;Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959 HUMAN|HGNC=362|UniProtKB=P54819 P54819 AK2 PTHR23359:SF227 NUCLEOTIDE KINASE ADENYLATE KINASE 2, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;adenylate kinase activity#GO:0004017;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;nucleoside diphosphate metabolic process#GO:0009132;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotide kinase#PC00172 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 HUMAN|HGNC=28346|UniProtKB=Q96ND0 Q96ND0 FAM210A PTHR21377:SF1 UNCHARACTERIZED PROTEIN FAM210A cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3446|UniProtKB=P11308 P11308 ERG PTHR11849:SF216 ETS TRANSCRIPTIONAL REGULATOR ERG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=28200|UniProtKB=Q96H86 Q96H86 ZNF764 PTHR24381:SF299 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 764 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=32417|UniProtKB=Q7Z3J3 Q7Z3J3 RGPD4 PTHR23138:SF87 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6816|UniProtKB=P20794 P20794 MAK PTHR24055:SF194 MITOGEN-ACTIVATED PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE MAK transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;establishment of organelle localization#GO:0051656;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;macromolecule metabolic process#GO:0043170;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;regulation of metabolic process#GO:0019222;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;signal transduction#GO:0007165;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;vesicle localization#GO:0051648;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;response to stimulus#GO:0050896;microtubule-based transport#GO:0099111;regulation of macromolecule metabolic process#GO:0060255;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=30200|UniProtKB=Q2TAL6 Q2TAL6 VWC2 PTHR46252:SF4 BRORIN FAMILY MEMBER BRORIN signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to growth factor#GO:0070848;negative regulation of cellular response to growth factor stimulus#GO:0090288;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular response to BMP stimulus#GO:0071773;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;negative regulation of signal transduction#GO:0009968 membrane protein complex#GO:0098796;extracellular region#GO:0005576;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;ion channel complex#GO:0034702;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;transmembrane transporter complex#GO:1902495;intrinsic component of plasma membrane#GO:0031226;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 HUMAN|HGNC=19291|UniProtKB=Q7Z407 Q7Z407 CSMD3 PTHR45656:SF9 PROTEIN CBR-CLEC-78 CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=1690|UniProtKB=O43866 O43866 CD5L PTHR48071:SF8 SRCR DOMAIN-CONTAINING PROTEIN CD5 ANTIGEN-LIKE extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=3999|UniProtKB=P02792 P02792 FTL PTHR11431:SF47 FERRITIN FERRITIN LIGHT CHAIN cation binding#GO:0043169;ferrous iron binding#GO:0008198;ferroxidase activity#GO:0004322;iron ion binding#GO:0005506;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;cellular cation homeostasis#GO:0030003;transition metal ion homeostasis#GO:0055076;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;cellular iron ion homeostasis#GO:0006879;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;iron ion homeostasis#GO:0055072;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 storage protein#PC00210 HUMAN|HGNC=20371|UniProtKB=Q86Y39 Q86Y39 NDUFA11 PTHR21382:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=44441|UniProtKB=C9JLJ4 C9JLJ4 USP17L13 PTHR24006:SF651 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 17-LIKE PROTEIN 4-RELATED thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 regulation of apoptotic process#GO:0042981;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;apoptotic process#GO:0006915;proteolysis#GO:0006508;biological regulation#GO:0065007;cell death#GO:0008219;protein deubiquitination#GO:0016579;regulation of cell death#GO:0010941;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of programmed cell death#GO:0043067;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=15519|UniProtKB=Q14137 Q14137 BOP1 PTHR17605:SF0 RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN RIBOSOME BIOGENESIS PROTEIN BOP1 ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome, large subunit precursor#GO:0030687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 ribosomal protein#PC00202 HUMAN|HGNC=27220|UniProtKB=A2RRL7 A2RRL7 TMEM213 PTHR36293:SF1 TRANSMEMBRANE PROTEIN 213 TRANSMEMBRANE PROTEIN 213 HUMAN|HGNC=7976|UniProtKB=P24468 P24468 NR2F2 PTHR24083:SF45 NUCLEAR HORMONE RECEPTOR COUP TRANSCRIPTION FACTOR 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;small molecule binding#GO:0036094;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;carboxylic acid binding#GO:0031406;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;lipid binding#GO:0008289;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cell differentiation#GO:0030154;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C4 zinc finger nuclear receptor#PC00169 HUMAN|HGNC=22448|UniProtKB=O60393 O60393 NOBOX PTHR47060:SF1 HOMEOBOX PROTEIN NOBOX HOMEOBOX PROTEIN NOBOX DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;reproductive system development#GO:0061458;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;reproductive structure development#GO:0048608;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;reproductive process#GO:0022414;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;sex differentiation#GO:0007548;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;developmental process involved in reproduction#GO:0003006;nucleobase-containing compound biosynthetic process#GO:0034654;reproduction#GO:0000003;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 homeodomain transcription factor#PC00119 HUMAN|HGNC=24577|UniProtKB=Q6ICB0 Q6ICB0 DESI1 PTHR12378:SF7 DESUMOYLATING ISOPEPTIDASE DESUMOYLATING ISOPEPTIDASE 1 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cysteine protease#PC00081 HUMAN|HGNC=29193|UniProtKB=Q9UPP2 Q9UPP2 IQSEC3 PTHR10663:SF318 GUANYL-NUCLEOTIDE EXCHANGE FACTOR IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 3 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=11917|UniProtKB=P20333 P20333 TNFRSF1B PTHR47386:SF1 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;tumor necrosis factor binding#GO:0043120;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;cytokine binding#GO:0019955 regulation of protein metabolic process#GO:0051246;gene expression#GO:0010467;regulation of cytokine production involved in immune response#GO:0002718;negative regulation of neuron death#GO:1901215;lymphocyte mediated immunity#GO:0002449;nervous system development#GO:0007399;production of molecular mediator of immune response#GO:0002440;regulation of biological process#GO:0050789;proteolysis#GO:0006508;regulation of adaptive immune response#GO:0002819;central nervous system development#GO:0007417;defense response#GO:0006952;positive regulation of cell development#GO:0010720;cellular protein metabolic process#GO:0044267;leukocyte activation#GO:0045321;macromolecule catabolic process#GO:0009057;membrane protein proteolysis#GO:0033619;regulation of multicellular organismal process#GO:0051239;regulation of immune response#GO:0050776;cellular metabolic process#GO:0044237;cell communication#GO:0007154;programmed cell death#GO:0012501;cellular response to DNA damage stimulus#GO:0006974;membrane protein ectodomain proteolysis#GO:0006509;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cell activation#GO:0001775;apoptotic signaling pathway#GO:0097190;negative regulation of cell death#GO:0060548;positive regulation of neurogenesis#GO:0050769;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of defense response#GO:0031347;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of neuron death#GO:1901214;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound catabolic process#GO:1901565;regulation of system process#GO:0044057;regulation of protein catabolic process#GO:0042176;regulation of multicellular organismal development#GO:2000026;inflammatory response#GO:0006954;cytokine production#GO:0001816;cell differentiation#GO:0030154;system development#GO:0048731;T cell proliferation#GO:0042098;cell death#GO:0008219;catabolic process#GO:0009056;regulation of immune system process#GO:0002682;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;immune effector process#GO:0002252;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;organonitrogen compound metabolic process#GO:1901564;lymphocyte proliferation#GO:0046651;nervous system process#GO:0050877;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;regulation of T cell proliferation#GO:0042129;regulation of inflammatory response#GO:0050727;regulation of immune effector process#GO:0002697;immune system process#GO:0002376;positive regulation of protein metabolic process#GO:0051247;regulation of mononuclear cell proliferation#GO:0032944;regulation of neurogenesis#GO:0050767;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;regulation of lymphocyte proliferation#GO:0050670;regulation of cell death#GO:0010941;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;system process#GO:0003008;positive regulation of cellular metabolic process#GO:0031325;protein catabolic process#GO:0030163;gliogenesis#GO:0042063;negative regulation of inflammatory response#GO:0050728;neuron death#GO:0070997;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;positive regulation of proteolysis#GO:0045862;regulation of cell activation#GO:0050865;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;apoptotic process#GO:0006915;intracellular signal transduction#GO:0035556;positive regulation of biological process#GO:0048518;mononuclear cell proliferation#GO:0032943;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;oligodendrocyte differentiation#GO:0048709;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;intrinsic apoptotic signaling pathway#GO:0097193;response to stress#GO:0006950;positive regulation of catabolic process#GO:0009896;regulation of production of molecular mediator of immune response#GO:0002700;positive regulation of protein catabolic process#GO:0045732;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;myelination#GO:0042552;regulation of cellular metabolic process#GO:0031323;positive regulation of multicellular organismal process#GO:0051240;positive regulation of nitrogen compound metabolic process#GO:0051173;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;positive regulation of cellular catabolic process#GO:0031331;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;glial cell differentiation#GO:0010001;adaptive immune response#GO:0002250;positive regulation of metabolic process#GO:0009893;regulation of lymphocyte mediated immunity#GO:0002706;regulation of gene expression#GO:0010468;regulation of lymphocyte activation#GO:0051249;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;regulation of response to external stimulus#GO:0032101;lymphocyte activation#GO:0046649;positive regulation of cell differentiation#GO:0045597;multicellular organism development#GO:0007275;leukocyte mediated immunity#GO:0002443;regulation of response to stress#GO:0080134;T cell mediated immunity#GO:0002456;regulation of cellular catabolic process#GO:0031329;positive regulation of developmental process#GO:0051094;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of leukocyte activation#GO:0002694;regulation of cellular protein metabolic process#GO:0032268;extrinsic apoptotic signaling pathway#GO:0097191;T cell activation#GO:0042110;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;negative regulation of response to external stimulus#GO:0032102;regulation of leukocyte proliferation#GO:0070663;positive regulation of cellular protein metabolic process#GO:0032270;generation of neurons#GO:0048699 transmembrane signal receptor#PC00197 Apoptosis signaling pathway#P00006>TNFR2#P00287 HUMAN|HGNC=32156|UniProtKB=Q8N7C0 Q8N7C0 LRRC52 PTHR46473:SF6 GH08155P LEUCINE-RICH REPEAT-CONTAINING PROTEIN 52 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ion channel regulator activity#GO:0099106;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;potassium channel regulator activity#GO:0015459;ion channel binding#GO:0044325;molecular function regulator#GO:0098772;protein binding#GO:0005515;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 HUMAN|HGNC=9914|UniProtKB=P0DJD4 P0DJD4 RBMY1C PTHR24012:SF685 RNA BINDING PROTEIN RNA-BINDING MOTIF PROTEIN, Y CHROMOSOME, FAMILY 1 MEMBER C-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of mRNA metabolic process#GO:1903311 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=27011|UniProtKB=A6NDS4 A6NDS4 TBC1D3B PTHR22957:SF537 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 3-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=3037|UniProtKB=Q14574 Q14574 DSC3 PTHR24025:SF12 DESMOGLEIN FAMILY MEMBER DESMOCOLLIN-3 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 cell junction#GO:0030054;cellular anatomical entity#GO:0110165;cell-cell junction#GO:0005911;anchoring junction#GO:0070161 cadherin#PC00057 HUMAN|HGNC=14422|UniProtKB=Q8WY36 Q8WY36 BBX PTHR13059:SF10 HMG-BOX TRANSCRIPTION FACTOR BBX HMG BOX TRANSCRIPTION FACTOR BBX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=6815|UniProtKB=P61326 P61326 MAGOH PTHR12638:SF2 PROTEIN MAGO NASHI HOMOLOG PROTEIN MAGO NASHI HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;exon-exon junction complex#GO:0035145;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=13001|UniProtKB=P17025 P17025 ZNF182 PTHR24377:SF218 IP01015P-RELATED ZINC FINGER PROTEIN 182 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=20605|UniProtKB=Q60I27 Q60I27 ALS2CL PTHR46089:SF1 ALSIN HOMOLOG ALS2 C-TERMINAL-LIKE PROTEIN HUMAN|HGNC=16140|UniProtKB=Q8TBE9 Q8TBE9 NANP PTHR46470:SF2 N-ACYLNEURAMINATE-9-PHOSPHATASE N-ACYLNEURAMINATE-9-PHOSPHATASE phosphatase#PC00181 HUMAN|HGNC=23062|UniProtKB=Q5GH72 Q5GH72 XKR7 PTHR16024:SF7 XK-RELATED PROTEIN XK-RELATED PROTEIN 7 cellular component biogenesis#GO:0044085;execution phase of apoptosis#GO:0097194;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;transport#GO:0006810;developmental process#GO:0032502;endomembrane system organization#GO:0010256;plasma membrane bounded cell projection organization#GO:0120036;lipid transport#GO:0006869;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anion transport#GO:0006820;apoptotic process#GO:0006915;lipid translocation#GO:0034204;cell death#GO:0008219;vesicle organization#GO:0016050;lipid localization#GO:0010876;phospholipid translocation#GO:0045332;cellular component assembly#GO:0022607;organophosphate ester transport#GO:0015748;phagocytosis#GO:0006909;organic anion transport#GO:0015711;ion transport#GO:0006811;endocytosis#GO:0006897;plasma membrane phospholipid scrambling#GO:0017121;vesicle-mediated transport#GO:0016192;programmed cell death#GO:0012501;regulation of membrane lipid distribution#GO:0097035;cellular component organization#GO:0016043;phospholipid transport#GO:0015914;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;anatomical structure development#GO:0048856;biological regulation#GO:0065007;plasma membrane bounded cell projection assembly#GO:0120031;apoptotic cell clearance#GO:0043277 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=23536|UniProtKB=Q9UQQ1 Q9UQQ1 NAALADL1 PTHR10404:SF50 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE AMINOPEPTIDASE NAALADL1 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153 HUMAN|HGNC=14399|UniProtKB=Q9H3G5 Q9H3G5 CPVL PTHR11802:SF98 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180 serine protease#PC00203 HUMAN|HGNC=23387|UniProtKB=Q76FK4 Q76FK4 NOL8 PTHR48029:SF2 NUCLEOLAR PROTEIN 8 NUCLEOLAR PROTEIN 8 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein localization to nucleus#GO:0034504;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=22921|UniProtKB=Q9BXI2 Q9BXI2 SLC25A2 PTHR45624:SF20 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL ORNITHINE TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;cation transmembrane transporter activity#GO:0008324;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215 L-amino acid transport#GO:0015807;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;mitochondrial transport#GO:0006839;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;L-alpha-amino acid transmembrane transport#GO:1902475;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825;mitochondrial transmembrane transport#GO:1990542 transporter#PC00227 HUMAN|HGNC=24124|UniProtKB=O96019 O96019 ACTL6A PTHR11937:SF487 ACTIN ACTIN-LIKE PROTEIN 6A chromatin binding#GO:0003682;binding#GO:0005488 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone H4 acetylation#GO:0043967;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;ATP-dependent chromatin remodeling#GO:0043044;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;peptidyl-lysine acetylation#GO:0018394;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;acetyltransferase complex#GO:1902493;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;SWI/SNF complex#GO:0016514;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 actin and actin related protein#PC00039 HUMAN|HGNC=28153|UniProtKB=Q0VDD7 Q0VDD7 C19orf57 PTHR14583:SF0 UNCHARACTERIZED PROTEIN C19ORF57 FAMILY MEMBER HYPOTHETICAL LOC304654 HUMAN|HGNC=12860|UniProtKB=O43829 O43829 ZBTB14 PTHR24399:SF5 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 14 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=10424|UniProtKB=P62701 P62701 RPS4X PTHR11581:SF35 30S/40S RIBOSOMAL PROTEIN S4 40S RIBOSOMAL PROTEIN S4, X ISOFORM structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=6613|UniProtKB=P53667 P53667 LIMK1 PTHR46485:SF7 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;contractile actin filament bundle assembly#GO:0030038;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;regulation of stress fiber assembly#GO:0051492;actin filament-based process#GO:0030029;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of biological process#GO:0048518;cellular component assembly#GO:0022607;stress fiber assembly#GO:0043149;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;neuron projection#GO:0043005;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 Cytoskeletal regulation by Rho GTPase#P00016>LIMK#P00524 HUMAN|HGNC=28339|UniProtKB=Q8NEQ6 Q8NEQ6 SRARP PTHR38494:SF1 STEROID RECEPTOR-ASSOCIATED AND REGULATED PROTEIN STEROID RECEPTOR-ASSOCIATED AND REGULATED PROTEIN nuclear receptor binding#GO:0016922;binding#GO:0005488;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;nuclear hormone receptor binding#GO:0035257;transcription factor binding#GO:0008134;signaling receptor binding#GO:0005102;hormone receptor binding#GO:0051427;DNA-binding transcription factor binding#GO:0140297;estrogen receptor binding#GO:0030331 response to organic cyclic compound#GO:0014070;signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;cellular response to steroid hormone stimulus#GO:0071383;regulation of signaling#GO:0023051;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;regulation of signal transduction#GO:0009966;intracellular steroid hormone receptor signaling pathway#GO:0030518;cellular response to organic cyclic compound#GO:0071407;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;steroid hormone mediated signaling pathway#GO:0043401;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;response to steroid hormone#GO:0048545 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=171|UniProtKB=Q04771 Q04771 ACVR1 PTHR23255:SF69 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II ACTIVIN RECEPTOR TYPE-1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 heart development#GO:0007507;signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;developmental process#GO:0032502;protein modification process#GO:0036211;transforming growth factor beta receptor signaling pathway#GO:0007179;phosphorus metabolic process#GO:0006793;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;tube morphogenesis#GO:0035239;vasculature development#GO:0001944;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;blood vessel morphogenesis#GO:0048514;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;tube development#GO:0035295;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;angiogenesis#GO:0001525;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;blood vessel development#GO:0001568;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 HUMAN|HGNC=17898|UniProtKB=Q9NYR9 Q9NYR9 NKIRAS2 PTHR46152:SF2 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN 2 HUMAN|HGNC=4580|UniProtKB=Q13002 Q13002 GRIK2 PTHR18966:SF38 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2 amino acid binding#GO:0016597;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;postsynaptic neurotransmitter receptor activity#GO:0098960;molecular transducer activity#GO:0060089;ion binding#GO:0043167;anion binding#GO:0043168;sodium channel activity#GO:0005272;glutamate binding#GO:0016595;signaling receptor activity#GO:0038023;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;monovalent inorganic cation transmembrane transporter activity#GO:0015077;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;transporter activity#GO:0005215;neurotransmitter binding#GO:0042165;transmembrane signaling receptor activity#GO:0004888;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;synaptic signaling#GO:0099536;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 presynapse#GO:0098793;membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;presynaptic membrane#GO:0042734;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>KA#P01026;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025;Huntington disease#P00029>Kainate receptor#P00796;Ionotropic glutamate receptor pathway#P00037>KA2#P01003 HUMAN|HGNC=1760|UniProtKB=Q9HBT6 Q9HBT6 CDH20 PTHR24027:SF84 CADHERIN-23 CADHERIN-20 cation binding#GO:0043169;binding#GO:0005488;cadherin binding#GO:0045296;cell adhesion molecule binding#GO:0050839;metal ion binding#GO:0046872;protein binding#GO:0005515;calcium ion binding#GO:0005509;ion binding#GO:0043167 cellular component assembly#GO:0022607;cell-cell junction organization#GO:0045216;cellular component biogenesis#GO:0044085;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;cell-cell adhesion via plasma-membrane adhesion molecules#GO:0098742;cell-cell adhesion#GO:0098609;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell junction organization#GO:0034330;cell junction assembly#GO:0034329;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=1396|UniProtKB=Q9P0X4 Q9P0X4 CACNA1I PTHR10037:SF209 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1I calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;system process#GO:0003008;transport#GO:0006810;regulation of secretion by cell#GO:1903530;action potential#GO:0001508;regulation of localization#GO:0032879;cation transport#GO:0006812;calcium ion transport#GO:0006816;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of transport#GO:0051049;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;positive regulation of exocytosis#GO:0045921;regulation of secretion#GO:0051046;secretion#GO:0046903;synaptic signaling#GO:0099536;divalent inorganic cation transport#GO:0072511;vesicle organization#GO:0016050;calcium-ion regulated exocytosis#GO:0017156;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;metal ion transport#GO:0030001;ion transport#GO:0006811;regulation of membrane potential#GO:0042391;positive regulation of secretion#GO:0051047;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cell communication#GO:0007154;nervous system process#GO:0050877;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;positive regulation of cellular process#GO:0048522;localization#GO:0051179;calcium ion import#GO:0070509;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of secretion by cell#GO:1903532;export from cell#GO:0140352 membrane protein complex#GO:0098796;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=9300|UniProtKB=P62714 P62714 PPP2CB PTHR45619:SF44 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT BETA ISOFORM protein phosphatase#PC00195 p53 pathway#P00059>PP2A#P04630;Wnt signaling pathway#P00057>PP2A#P01438;p53 pathway feedback loops 2#P04398>PP2A-C#P04659;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 HUMAN|HGNC=9527|UniProtKB=O75475 O75475 PSIP1 PTHR12550:SF42 HEPATOMA-DERIVED GROWTH FACTOR-RELATED PC4 AND SFRS1-INTERACTING PROTEIN nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 transcription cofactor#PC00217 HUMAN|HGNC=29392|UniProtKB=Q96JF6 Q96JF6 ZNF594 PTHR24376:SF207 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 594-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13020|UniProtKB=Q86WZ6 Q86WZ6 ZNF227 PTHR24376:SF76 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 227 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=27740|UniProtKB=P0CF97 P0CF97 FAM200B PTHR45935:SF6 PROTEIN ZBED8-RELATED PROTEIN FAM200B HUMAN|HGNC=10347|UniProtKB=P61927 P61927 RPL37 PTHR10768:SF22 60S RIBOSOMAL PROTEIN L37 60S RIBOSOMAL PROTEIN L37 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=17419|UniProtKB=Q6IS14 Q6IS14 EIF5AL1 PTHR11673:SF25 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-1-LIKE RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;positive regulation of cellular protein metabolic process#GO:0032270;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 translation initiation factor#PC00224 HUMAN|HGNC=12942|UniProtKB=P51786 P51786 ZNF157 PTHR24377:SF34 IP01015P-RELATED ZINC FINGER PROTEIN 157 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=9553|UniProtKB=P62333 P62333 PSMC6 PTHR23073:SF76 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 10B positive regulation of gene expression#GO:0010628;cellular component biogenesis#GO:0044085;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;protein catabolic process#GO:0030163;gene expression#GO:0010467;regulation of cellular component organization#GO:0051128;regulation of RNA biosynthetic process#GO:2001141;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;RNA polymerase II preinitiation complex assembly#GO:0051123;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;proteolysis#GO:0006508;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular protein-containing complex assembly#GO:0034622;positive regulation of transcription, DNA-templated#GO:0045893;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;regulation of DNA-templated transcription, initiation#GO:2000142;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;regulation of cellular process#GO:0050794;regulation of transcription initiation from RNA polymerase II promoter#GO:0060260;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of transcription initiation from RNA polymerase II promoter#GO:0060261;regulation of transcription by RNA polymerase II#GO:0006357;protein-containing complex assembly#GO:0065003;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of protein-containing complex assembly#GO:0043254;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;catabolic process#GO:0009056;positive regulation of RNA polymerase II transcription preinitiation complex assembly#GO:0045899;positive regulation of cellular component biogenesis#GO:0044089;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of protein-containing complex assembly#GO:0031334;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;ubiquitin-dependent ERAD pathway#GO:0030433;positive regulation of DNA-templated transcription, initiation#GO:2000144;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;catalytic complex#GO:1902494;intracellular#GO:0005622;endopeptidase complex#GO:1905369;proteasome complex#GO:0000502;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;proteasome regulatory particle, base subcomplex#GO:0008540 protease#PC00190 HUMAN|HGNC=9060|UniProtKB=P51178 P51178 PLCD1 PTHR10336:SF80 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 HUMAN|HGNC=5952|UniProtKB=Q9NSI5 Q9NSI5 IGSF5 PTHR44991:SF1 IMMUNOGLOBULIN SUPERFAMILY MEMBER 5 IMMUNOGLOBULIN SUPERFAMILY MEMBER 5 immunoglobulin#PC00123 HUMAN|HGNC=26040|UniProtKB=Q8N5Y8 Q8N5Y8 PARP16 PTHR21328:SF2 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP16 HUMAN|HGNC=13818|UniProtKB=Q9H2X9 Q9H2X9 SLC12A5 PTHR11827:SF54 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 5 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;chemical synaptic transmission#GO:0007268;ion homeostasis#GO:0050801;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;signaling#GO:0023052;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;chloride transport#GO:0006821;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cell communication#GO:0007154;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;regulation of cellular component size#GO:0032535;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065 secondary carrier transporter#PC00258 HUMAN|HGNC=4195|UniProtKB=P35557 P35557 GCK PTHR19443:SF3 HEXOKINASE HEXOKINASE-4 transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;catalytic activity#GO:0003824 purine nucleoside diphosphate metabolic process#GO:0009135;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;protein secretion#GO:0009306;regulation of localization#GO:0032879;nucleobase-containing compound metabolic process#GO:0006139;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;hormone secretion#GO:0046879;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;establishment of localization#GO:0051234;ATP generation from ADP#GO:0006757;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;secretion#GO:0046903;regulation of secretion#GO:0051046;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;oxidation-reduction process#GO:0055114;insulin secretion#GO:0030073;hormone transport#GO:0009914;regulation of protein localization#GO:0032880;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;purine ribonucleoside diphosphate metabolic process#GO:0009179;regulation of peptide hormone secretion#GO:0090276;oxoacid metabolic process#GO:0043436;regulation of protein secretion#GO:0050708;generation of precursor metabolites and energy#GO:0006091;nucleotide phosphorylation#GO:0046939;nucleoside diphosphate phosphorylation#GO:0006165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;peptide transport#GO:0015833;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;glucose 6-phosphate metabolic process#GO:0051156;protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;regulation of cellular process#GO:0050794;protein transport#GO:0015031;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;protein localization to extracellular region#GO:0071692;regulation of establishment of protein localization#GO:0070201;export from cell#GO:0140352;regulation of peptide transport#GO:0090087;small molecule metabolic process#GO:0044281;cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;macromolecule localization#GO:0033036;regulation of signaling#GO:0023051;transport#GO:0006810;regulation of insulin secretion#GO:0050796;peptide secretion#GO:0002790;cellular homeostasis#GO:0019725;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of peptide secretion#GO:0002791;regulation of transport#GO:0051049;organic cyclic compound metabolic process#GO:1901360;peptide hormone secretion#GO:0030072;regulation of hormone secretion#GO:0046883;signal release#GO:0023061;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;phosphorylation#GO:0016310;organic substance catabolic process#GO:1901575;regulation of protein transport#GO:0051223;signaling#GO:0023052;carbohydrate metabolic process#GO:0005975;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;secretion by cell#GO:0032940;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;ADP metabolic process#GO:0046031;organonitrogen compound metabolic process#GO:1901564;homeostatic process#GO:0042592;glucose homeostasis#GO:0042593;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;biological regulation#GO:0065007;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 HUMAN|HGNC=30435|UniProtKB=Q5SVJ3 Q5SVJ3 C1orf100 PTHR31763:SF2 HYPOTHETICAL PROTEIN LOC689766 HYPOTHETICAL PROTEIN LOC689766 HUMAN|HGNC=12217|UniProtKB=A0A589 A0A589 TRBV4-3 PTHR23268:SF98 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 4-3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=16244|UniProtKB=Q8NDH3 Q8NDH3 NPEPL1 PTHR11963:SF4 LEUCINE AMINOPEPTIDASE-RELATED AMINOPEPTIDASE NPEPL1-RELATED metalloprotease#PC00153 HUMAN|HGNC=4197|UniProtKB=Q9NP62 Q9NP62 GCM1 PTHR12414:SF6 GLIAL CELLS MISSING RELATED/GLIDE CHORION-SPECIFIC TRANSCRIPTION FACTOR GCMA cell differentiation#GO:0030154;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;gliogenesis#GO:0042063;cellular process#GO:0009987;nervous system development#GO:0007399 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=16457|UniProtKB=P57077 P57077 MAP3K7CL PTHR47140:SF1 MAP3K7 C-TERMINAL-LIKE PROTEIN MAP3K7 C-TERMINAL-LIKE PROTEIN cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Ras Pathway#P04393>TAK#P04575;TGF-beta signaling pathway#P00052>TAK#P01285 HUMAN|HGNC=18966|UniProtKB=Q9Y600 Q9Y600 CSAD PTHR45677:SF7 GLUTAMATE DECARBOXYLASE-RELATED CYSTEINE SULFINIC ACID DECARBOXYLASE decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 HUMAN|HGNC=1996|UniProtKB=P17540 P17540 CKMT2 PTHR11547:SF19 ARGININE OR CREATINE KINASE CREATINE KINASE S-TYPE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 amino acid kinase#PC00045 HUMAN|HGNC=18538|UniProtKB=Q9BXS6 Q9BXS6 NUSAP1 PTHR15874:SF1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular localization#GO:0051641;cell division#GO:0051301;organelle localization#GO:0051640;membrane organization#GO:0061024;nuclear division#GO:0000280;cell cycle process#GO:0022402;chromosome condensation#GO:0030261;microtubule cytoskeleton organization#GO:0000226;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;cytoskeleton-dependent cytokinesis#GO:0061640;cytoskeleton organization#GO:0007010;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;establishment of organelle localization#GO:0051656;cytokinesis#GO:0000910;spindle localization#GO:0051653;nuclear chromosome segregation#GO:0098813;membrane fission#GO:0090148;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;cellular process#GO:0009987;establishment of spindle localization#GO:0051293;mitotic chromosome condensation#GO:0007076;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle localization#GO:0040001;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;organelle organization#GO:0006996;cell cycle#GO:0007049;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;spindle microtubule#GO:0005876;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule#GO:0005874 HUMAN|HGNC=29590|UniProtKB=Q7Z7A3 Q7Z7A3 CTU1 PTHR11807:SF12 ATPASES OF THE PP SUPERFAMILY-RELATED CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=17999|UniProtKB=Q6P5Z2 Q6P5Z2 PKN3 PTHR24356:SF318 SERINE/THREONINE-PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE N3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 HUMAN|HGNC=4068|UniProtKB=Q9H0R8 Q9H0R8 GABARAPL1 PTHR10969:SF30 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 1 enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;signaling receptor binding#GO:0005102;ubiquitin-like protein ligase binding#GO:0044389 cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;response to extracellular stimulus#GO:0009991;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to starvation#GO:0009267;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;mitochondrion organization#GO:0007005;protein metabolic process#GO:0019538;cellular response to extracellular stimulus#GO:0031668;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;cellular response to external stimulus#GO:0071496;autophagosome assembly#GO:0000045;autophagosome organization#GO:1905037;cellular response to stress#GO:0033554;autophagy#GO:0006914 bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vacuolar membrane#GO:0005774;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;whole membrane#GO:0098805 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=25883|UniProtKB=Q9H7S9 Q9H7S9 ZNF703 PTHR12522:SF2 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN 703 repressing transcription factor binding#GO:0070491;protein binding#GO:0005515;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=16395|UniProtKB=Q9BXB5 Q9BXB5 OSBPL10 PTHR10972:SF47 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 10 small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;sterol binding#GO:0032934;lipid binding#GO:0008289;lipid transporter activity#GO:0005319;transporter activity#GO:0005215;cholesterol binding#GO:0015485 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28733|UniProtKB=Q6JVE5 Q6JVE5 LCN12 PTHR11430:SF12 LIPOCALIN EPIDIDYMAL-SPECIFIC LIPOCALIN-12 binding#GO:0005488 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transfer/carrier protein#PC00219 HUMAN|HGNC=17897|UniProtKB=O75691 O75691 UTP20 PTHR17695:SF11 UNCHARACTERIZED SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 HUMAN|HGNC=32931|UniProtKB=Q6B9Z1 Q6B9Z1 IGFL4 PTHR34827:SF1 INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 3-RELATED INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 4 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 HUMAN|HGNC=19899|UniProtKB=Q9P243 Q9P243 ZFAT PTHR24388:SF73 ZINC FINGER PROTEIN ZINC FINGER PROTEIN ZFAT cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=19583|UniProtKB=O95013 O95013 OR4F21 PTHR48002:SF1 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4F21-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=26764|UniProtKB=Q5VWM5 Q5VWM5 PRAMEF15 PTHR14224:SF100 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 11-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=28580|UniProtKB=P59025 P59025 RTP1 PTHR14402:SF19 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;system process#GO:0003008;nitrogen compound transport#GO:0071705;detection of chemical stimulus#GO:0009593;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein insertion into membrane#GO:0051205;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;detection of stimulus#GO:0051606;nervous system process#GO:0050877;cellular component organization#GO:0016043;sensory perception of chemical stimulus#GO:0007606;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;sensory perception#GO:0007600 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|HGNC=17840|UniProtKB=Q9BSY4 Q9BSY4 CHCHD5 PTHR47106:SF1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 5 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 5 HUMAN|HGNC=6265|UniProtKB=P48050 P48050 KCNJ4 PTHR11767:SF53 INWARD RECTIFIER POTASSIUM CHANNEL INWARD RECTIFIER POTASSIUM CHANNEL 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 regulation of transmembrane transport#GO:0034762;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of ion transmembrane transport#GO:0034765;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;regulation of ion transport#GO:0043269;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|Gene=ACOT7L|UniProtKB=Q6ZUV0 Q6ZUV0 ACOT7L PTHR11049:SF29 ACYL COENZYME A THIOESTER HYDROLASE CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE-LIKE-RELATED hydrolase activity, acting on ester bonds#GO:0016788;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;thiolester hydrolase activity#GO:0016790;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;fatty acid biosynthetic process#GO:0006633;metabolic process#GO:0008152;long-chain fatty acid metabolic process#GO:0001676;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;extracellular region#GO:0005576;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cytosol#GO:0005829;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 esterase#PC00097 HUMAN|HGNC=21479|UniProtKB=Q8N8Z6 Q8N8Z6 DCBLD1 PTHR46806:SF1 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=24764|UniProtKB=Q2TAL5 Q2TAL5 SMTNL2 PTHR23167:SF37 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED SMOOTHELIN-LIKE PROTEIN 2 cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;organelle organization#GO:0006996 supramolecular complex#GO:0099080;microtubule organizing center#GO:0005815;cellular anatomical entity#GO:0110165;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856 HUMAN|HGNC=18518|UniProtKB=O75792 O75792 RNASEH2A PTHR10954:SF7 RIBONUCLEASE H2 SUBUNIT A RIBONUCLEASE H2 SUBUNIT A catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824;endoribonuclease activity#GO:0004521;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;endonuclease activity#GO:0004519 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;mismatch repair#GO:0006298;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular response to stress#GO:0033554;cellular macromolecule catabolic process#GO:0044265;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;intracellular#GO:0005622 endoribonuclease#PC00094 DNA replication#P00017>RNase H#P00538 HUMAN|HGNC=24727|UniProtKB=A0AVK6 A0AVK6 E2F8 PTHR12081:SF40 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F8 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=30309|UniProtKB=O15258 O15258 RER1 PTHR10743:SF25 PROTEIN RER1 PROTEIN RER1 cellular localization#GO:0051641;protein localization to endoplasmic reticulum#GO:0070972;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;maintenance of location#GO:0051235;maintenance of location in cell#GO:0051651;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;biological regulation#GO:0065007;protein localization to organelle#GO:0033365 bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;integral component of Golgi membrane#GO:0030173;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 HUMAN|HGNC=3418|UniProtKB=P07814 P07814 EPRS1 PTHR43382:SF2 PROLYL-TRNA SYNTHETASE BIFUNCTIONAL GLUTAMATE/PROLINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 HUMAN|HGNC=6973|UniProtKB=Q00987 Q00987 MDM2 PTHR13844:SF15 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D E3 UBIQUITIN-PROTEIN LIGASE MDM2 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;ubiquitin-protein transferase activity#GO:0004842;regulatory region nucleic acid binding#GO:0001067;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;ubiquitin protein ligase activity#GO:0061630;DNA binding#GO:0003677;ubiquitin-like protein ligase activity#GO:0061659;heterocyclic compound binding#GO:1901363;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;catalytic activity, acting on a protein#GO:0140096 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 p53 pathway#P00059>Mdm2#P01483;Ubiquitin proteasome pathway#P00060>E3#P01490;P53 pathway feedback loops 1#P04392>MDM-2#G04682;p53 pathway feedback loops 2#P04398>Mdm2#P04663;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#P04496;P53 pathway feedback loops 1#P04392>Mdm2#P04536;p53 pathway feedback loops 2#P04398>MDM-2#G04709;p53 pathway#P00059>MDM-2#G01563;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>Mdm2#G04674 HUMAN|HGNC=6930|UniProtKB=Q01718 Q01718 MC2R PTHR22750:SF3 G-PROTEIN COUPLED RECEPTOR ADRENOCORTICOTROPIC HORMONE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=6587|UniProtKB=Q86WI0 Q86WI0 LHFPL1 PTHR12489:SF15 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 1 PROTEIN cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=3591|UniProtKB=Q9Y4F1 Q9Y4F1 FARP1 PTHR45858:SF2 FERM DOMAIN CONTAINING PROTEIN FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 1 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Rac GTPase binding#GO:0048365;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 HUMAN|HGNC=13041|UniProtKB=Q8NDW4 Q8NDW4 ZNF248 PTHR24381:SF68 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 248 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=29535|UniProtKB=Q9Y483 Q9Y483 MTF2 PTHR12628:SF12 POLYCOMB-LIKE TRANSCRIPTION FACTOR METAL-RESPONSE ELEMENT-BINDING TRANSCRIPTION FACTOR 2 nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;methylated histone binding#GO:0035064;histone binding#GO:0042393;modification-dependent protein binding#GO:0140030 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=4567|UniProtKB=Q14451 Q14451 GRB7 PTHR11243:SF25 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to insulin#GO:0032868;response to peptide hormone#GO:0043434;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;cellular response to hormone stimulus#GO:0032870;response to peptide#GO:1901652;regulation of signal transduction#GO:0009966;cellular response to insulin stimulus#GO:0032869;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;insulin receptor signaling pathway#GO:0008286;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular response to peptide#GO:1901653;cellular response to peptide hormone stimulus#GO:0071375;cellular process#GO:0009987;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to hormone#GO:0009725;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Grb7#P00228 HUMAN|HGNC=3690|UniProtKB=P22607 P22607 FGFR3 PTHR24416:SF505 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR 3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;growth factor binding#GO:0019838;fibroblast growth factor binding#GO:0017134;protein binding#GO:0005515;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 FGF signaling pathway#P00021>FGFR1-4#P00636 HUMAN|HGNC=29806|UniProtKB=Q8N386 Q8N386 LRRC25 PTHR20878:SF0 LEUCINE-RICH REPEAT CONTAINING PROTEIN 25 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 25 HUMAN|HGNC=4203|UniProtKB=Q02742 Q02742 GCNT1 PTHR19297:SF96 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE glycosyltransferase#PC00111 HUMAN|HGNC=15205|UniProtKB=Q8NGJ9 Q8NGJ9 OR51T1 PTHR26450:SF6 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51T1 transmembrane signal receptor#PC00197 HUMAN|HGNC=32521|UniProtKB=Q5FYB1 Q5FYB1 ARSI PTHR10342:SF68 ARYLSULFATASE ARYLSULFATASE I HUMAN|HGNC=24627|UniProtKB=Q96PD2 Q96PD2 DCBLD2 PTHR46806:SF3 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=8535|UniProtKB=Q99571 Q99571 P2RX4 PTHR10125:SF18 P2X PURINOCEPTOR P2X PURINOCEPTOR 4 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=21537|UniProtKB=Q5T4T6 Q5T4T6 SYCP2L PTHR15607:SF14 SYNAPTONEMAL COMPLEX PROTEIN-RELATED SYNAPTONEMAL COMPLEX PROTEIN 2-LIKE chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=16309|UniProtKB=A6NI73 A6NI73 LILRA5 PTHR11738:SF182 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 5 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=25812|UniProtKB=Q9H8P0 Q9H8P0 SRD5A3 PTHR14624:SF0 DFG10 PROTEIN POLYPRENOL REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;alcohol biosynthetic process#GO:0046165;protein modification process#GO:0036211;organic hydroxy compound biosynthetic process#GO:1901617;lipid catabolic process#GO:0016042;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular lipid catabolic process#GO:0044242;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;organic hydroxy compound metabolic process#GO:1901615;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;small molecule catabolic process#GO:0044282;protein N-linked glycosylation#GO:0006487;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|Ensembl=ENSG00000284283|UniProtKB=A0A1W2PPE2 A0A1W2PPE2 TAF11L4 PTHR13218:SF18 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TAFII28 DOMAIN-CONTAINING PROTEIN transcription coactivator activity#GO:0003713;molecular function regulator#GO:0098772;protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription factor binding#GO:0008134;binding#GO:0005488 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;transcription initiation from RNA polymerase II promoter#GO:0006367;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;RNA polymerase II preinitiation complex assembly#GO:0051123;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;transcription preinitiation complex assembly#GO:0070897;DNA-templated transcription, initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;DNA-directed RNA polymerase complex#GO:0000428;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;transcription factor TFIID complex#GO:0005669;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;transcription regulator complex#GO:0005667;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|Gene=YP015_HUMAN|UniProtKB=Q6ZTK2 Q6ZTK2 - PTHR37860:SF1 AGAP008810-PA VWFD DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=4588|UniProtKB=O15399 O15399 GRIN2D PTHR18966:SF385 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2D amino acid binding#GO:0016597;cation channel activity#GO:0005261;signaling receptor activity#GO:0038023;inorganic molecular entity transmembrane transporter activity#GO:0015318;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;neurotransmitter receptor activity#GO:0030594;voltage-gated cation channel activity#GO:0022843;neurotransmitter binding#GO:0042165;transporter activity#GO:0005215;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;carboxylic acid binding#GO:0031406;molecular transducer activity#GO:0060089;organic acid binding#GO:0043177;ion binding#GO:0043167;anion binding#GO:0043168;inorganic cation transmembrane transporter activity#GO:0022890;glutamate binding#GO:0016595;ligand-gated channel activity#GO:0022834 signal transduction#GO:0007165;chemical synaptic transmission, postsynaptic#GO:0099565;system process#GO:0003008;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;regulation of membrane potential#GO:0042391;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;nervous system process#GO:0050877;cellular process#GO:0009987;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell junction#GO:0030054;ion channel complex#GO:0034702;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;integral component of plasma membrane#GO:0005887;postsynaptic density membrane#GO:0098839;plasma membrane region#GO:0098590;ionotropic glutamate receptor complex#GO:0008328;intrinsic component of plasma membrane#GO:0031226;postsynapse#GO:0098794;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Ionotropic glutamate receptor pathway#P00037>NR2C#P01006;Ionotropic glutamate receptor pathway#P00037>NR2D#P01005;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060 HUMAN|HGNC=33202|UniProtKB=P0CH99 P0CH99 ZNF705D PTHR24381:SF303 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 705A-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6217|UniProtKB=Q9BVA0 Q9BVA0 KATNB1 PTHR19845:SF0 KATANIN P80 SUBUNIT KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1 cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;cellular protein complex disassembly#GO:0043624;protein-containing complex disassembly#GO:0032984;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule depolymerization#GO:0007019;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14711|UniProtKB=Q8NGM8 Q8NGM8 OR6M1 PTHR26454:SF51 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6M1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=18215|UniProtKB=Q8TCG2 Q8TCG2 PI4K2B PTHR12865:SF6 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2-BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;Golgi organization#GO:0007030;endomembrane system organization#GO:0010256;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;cellular component organization#GO:0016043;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular component organization or biogenesis#GO:0071840;endosome organization#GO:0007032;glycerolipid metabolic process#GO:0046486;organelle organization#GO:0006996;vesicle organization#GO:0016050;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;trans-Golgi network#GO:0005802;lytic vacuole membrane#GO:0098852;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 kinase#PC00137 HUMAN|HGNC=15624|UniProtKB=Q96JL9 Q96JL9 ZNF333 PTHR24377:SF907 IP01015P-RELATED ZINC FINGER PROTEIN 333 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=11845|UniProtKB=Q9Y490 Q9Y490 TLN1 PTHR19981:SF7 TALIN TALIN-1 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 platelet activation#GO:0030168;biological adhesion#GO:0022610;cell-cell adhesion#GO:0098609;regulation of body fluid levels#GO:0050878;homotypic cell-cell adhesion#GO:0034109;wound healing#GO:0042060;cell adhesion#GO:0007155;cellular process#GO:0009987;hemostasis#GO:0007599;coagulation#GO:0050817;cell activation#GO:0001775;response to stimulus#GO:0050896;response to wounding#GO:0009611;response to stress#GO:0006950;platelet aggregation#GO:0070527;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596 anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 Integrin signalling pathway#P00034>Talin#P00943 HUMAN|HGNC=3719|UniProtKB=Q00688 Q00688 FKBP3 PTHR46493:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 chaperone#PC00072 HUMAN|HGNC=544|UniProtKB=P08133 P08133 ANXA6 PTHR10502:SF19 ANNEXIN ANNEXIN A6 nucleotide binding#GO:0000166;inorganic molecular entity transmembrane transporter activity#GO:0015318;cation channel activity#GO:0005261;carbohydrate derivative binding#GO:0097367;calcium-dependent phospholipid binding#GO:0005544;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;sterol binding#GO:0032934;ion transmembrane transporter activity#GO:0015075;glycosaminoglycan binding#GO:0005539;phospholipid binding#GO:0005543;transmembrane transporter activity#GO:0022857;organic cyclic compound binding#GO:0097159;steroid binding#GO:0005496;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;actin binding#GO:0003779;cholesterol binding#GO:0015485;calcium ion transmembrane transporter activity#GO:0015085;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;metal ion binding#GO:0046872;channel activity#GO:0015267;transporter activity#GO:0005215;cation binding#GO:0043169;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;purine nucleotide binding#GO:0017076;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;phosphatidylserine binding#GO:0001786;nucleoside phosphate binding#GO:1901265;calcium ion binding#GO:0005509;protein binding#GO:0005515;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;regulation of muscle contraction#GO:0006937;divalent inorganic cation homeostasis#GO:0072507;membrane organization#GO:0061024;plasma membrane organization#GO:0007009;system process#GO:0003008;regulation of sequestering of calcium ion#GO:0051282;endomembrane system organization#GO:0010256;regulation of localization#GO:0032879;skeletal system development#GO:0001501;regulation of biological process#GO:0050789;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;cellular calcium ion homeostasis#GO:0006874;apoptotic process#GO:0006915;cellular developmental process#GO:0048869;cellular cation homeostasis#GO:0030003;regulation of multicellular organismal process#GO:0051239;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;cation homeostasis#GO:0055080;regulation of cellular localization#GO:0060341;cellular ion homeostasis#GO:0006873;mesenchymal cell differentiation#GO:0048762;cellular component organization or biogenesis#GO:0071840;apoptotic signaling pathway#GO:0097190;response to wounding#GO:0009611;response to stress#GO:0006950;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;mesenchyme development#GO:0060485;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065;locomotion#GO:0040011;cellular metal ion homeostasis#GO:0006875;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;animal organ development#GO:0048513;neural crest cell development#GO:0014032;developmental process#GO:0032502;growth#GO:0040007;wound healing#GO:0042060;regulation of system process#GO:0044057;cellular homeostasis#GO:0019725;sequestering of calcium ion#GO:0051208;bone development#GO:0060348;cell differentiation#GO:0030154;system development#GO:0048731;ion homeostasis#GO:0050801;cell death#GO:0008219;cellular divalent inorganic cation homeostasis#GO:0072503;mitochondrial calcium ion homeostasis#GO:0051560;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;cellular response to stimulus#GO:0051716;developmental growth#GO:0048589;multicellular organism development#GO:0007275;homeostatic process#GO:0042592;connective tissue development#GO:0061448;cell motility#GO:0048870;chondrocyte differentiation#GO:0002062;cellular process#GO:0009987;chemical homeostasis#GO:0048878;tissue development#GO:0009888;cellular chemical homeostasis#GO:0055082;cell development#GO:0048468;localization#GO:0051179;response to stimulus#GO:0050896;maintenance of location in cell#GO:0051651;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;stem cell differentiation#GO:0048863;cartilage development#GO:0051216;cell migration#GO:0016477;negative regulation of sequestering of calcium ion#GO:0051283;muscle system process#GO:0003012;muscle contraction#GO:0006936 cell junction#GO:0030054;cytoplasm#GO:0005737;cell-substrate junction#GO:0030055;cellular anatomical entity#GO:0110165;anchoring junction#GO:0070161;intracellular#GO:0005622;focal adhesion#GO:0005925 calcium-binding protein#PC00060 HUMAN|HGNC=16123|UniProtKB=Q9NT22 Q9NT22 EMILIN3 PTHR15427:SF2 EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER EMILIN-3 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=5881|UniProtKB=A0A075B6I6 A0A075B6I6 IGLV1-50 PTHR23267:SF456 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 1-40-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=29991|UniProtKB=Q58A45 Q58A45 PAN3 PTHR12272:SF11 DEADENYLATION COMPLEX SUBUNIT PAN3 PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;cellular component biogenesis#GO:0044085;negative regulation of biological process#GO:0048519;positive regulation of organelle organization#GO:0010638;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;deadenylation-dependent decapping of nuclear-transcribed mRNA#GO:0000290;regulation of cellular component organization#GO:0051128;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;mRNA catabolic process#GO:0006402;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;positive regulation of cellular component biogenesis#GO:0044089;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;positive regulation of biological process#GO:0048518;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;nuclear-transcribed mRNA catabolic process#GO:0000956;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;aromatic compound catabolic process#GO:0019439;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;organic cyclic compound catabolic process#GO:1901361;cytoplasmic mRNA processing body assembly#GO:0033962;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;P-body#GO:0000932;intracellular#GO:0005622;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 exoribonuclease#PC00099 HUMAN|HGNC=28536|UniProtKB=Q8IYX1 Q8IYX1 TBC1D21 PTHR22957:SF489 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 21 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;molecular function regulator#GO:0098772;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;regulation of GTPase activity#GO:0043087;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 HUMAN|HGNC=25818|UniProtKB=Q9H8M2 Q9H8M2 BRD9 PTHR22881:SF4 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN-CONTAINING PROTEIN 9 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=20883|UniProtKB=Q8N9F7 Q8N9F7 GDPD1 PTHR42758:SF1 PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C LYSOPHOSPHOLIPASE D GDPD1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;lysophospholipase activity#GO:0004622;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0004620;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;alcohol metabolic process#GO:0006066;glycerolipid catabolic process#GO:0046503;lipid catabolic process#GO:0016042;cellular nitrogen compound metabolic process#GO:0034641;glycerophospholipid catabolic process#GO:0046475;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;organophosphate metabolic process#GO:0019637;organic substance catabolic process#GO:1901575;cellular lipid metabolic process#GO:0044255;cellular lipid catabolic process#GO:0044242;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 phospholipase#PC00186 HUMAN|HGNC=13049|UniProtKB=Q9Y2P7 Q9Y2P7 ZNF256 PTHR24377:SF685 IP01015P-RELATED ZINC FINGER PROTEIN 256 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=24757|UniProtKB=Q6IPR3 Q6IPR3 TYW3 PTHR23245:SF31 TRNA METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3 HOMOLOG tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA methyltransferase#PC00033 HUMAN|HGNC=12424|UniProtKB=O00295 O00295 TULP2 PTHR16517:SF24 TUBBY-RELATED TUBBY-RELATED PROTEIN 2 localization#GO:0051179;cellular localization#GO:0051641;cellular macromolecule localization#GO:0070727;macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;cellular protein localization#GO:0034613;protein localization to organelle#GO:0033365;cellular process#GO:0009987;protein localization#GO:0008104 protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=16160|UniProtKB=Q9H147 Q9H147 DNTTIP1 PTHR23399:SF2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 HUMAN|HGNC=11841|UniProtKB=Q9UKI8 Q9UKI8 TLK1 PTHR22974:SF22 MIXED LINEAGE PROTEIN KINASE SERINE/THREONINE-PROTEIN KINASE TOUSLED-LIKE 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 chromatin assembly or disassembly#GO:0006333;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of cellular component organization#GO:0051128;peptidyl-amino acid modification#GO:0018193;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;chromosome segregation#GO:0007059;phosphate-containing compound metabolic process#GO:0006796;regulation of chromatin assembly or disassembly#GO:0001672;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of chromatin organization#GO:1902275;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;chromosome organization#GO:0051276;biological regulation#GO:0065007;chromatin organization#GO:0006325;peptidyl-serine modification#GO:0018209 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=2524|UniProtKB=P40313 P40313 CTRL PTHR24250:SF28 CHYMOTRYPSIN-RELATED CHYMOTRYPSIN-LIKE PROTEASE CTRL-1 serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 serine protease#PC00203 HUMAN|HGNC=4431|UniProtKB=O14653 O14653 GOSR2 PTHR21230:SF1 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 2 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;organelle fusion#GO:0048284;establishment of protein localization to vacuole#GO:0072666;vacuolar transport#GO:0007034;protein localization to vacuole#GO:0072665;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;cytosolic transport#GO:0016482;protein localization#GO:0008104;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;Golgi to vacuole transport#GO:0006896;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;Golgi-associated vesicle#GO:0005798;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 SNARE protein#PC00034 HUMAN|HGNC=30688|UniProtKB=Q86VP6 Q86VP6 CAND1 PTHR12696:SF1 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=33826|UniProtKB=Q6P1X6 Q6P1X6 C8orf82 PTHR31449:SF3 UPF0598 PROTEIN C8ORF82 UPF0598 PROTEIN C8ORF82 HUMAN|HGNC=16685|UniProtKB=Q6P161 Q6P161 MRPL54 PTHR28595:SF1 39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial large ribosomal subunit#GO:0005762;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;organellar ribosome#GO:0000313;protein-containing complex#GO:0032991;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=30237|UniProtKB=Q6P1N0 Q6P1N0 CC2D1A PTHR13076:SF8 UNCHARACTERIZED COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1A cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=37073|UniProtKB=A6NHX0 A6NHX0 CASTOR2 PTHR31131:SF2 CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 2-RELATED signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;cellular response to nitrogen compound#GO:1901699;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;TORC1 signaling#GO:0038202;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;negative regulation of response to stimulus#GO:0048585;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to nitrogen compound#GO:1901698;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=24212|UniProtKB=Q8N5K1 Q8N5K1 CISD2 PTHR13680:SF33 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 2 metal cluster binding#GO:0051540;iron-sulfur cluster binding#GO:0051536;binding#GO:0005488 process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411;organelle organization#GO:0006996;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;autophagy of mitochondrion#GO:0000422;mitochondrion organization#GO:0007005;cellular process#GO:0009987;organelle disassembly#GO:1903008;autophagy#GO:0006914;cellular catabolic process#GO:0044248;metabolic process#GO:0008152 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=14235|UniProtKB=Q9NRN7 Q9NRN7 AASDHPPT PTHR12215:SF10 PHOSPHOPANTETHEINE TRANSFERASE L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 transferase#PC00220 HUMAN|HGNC=6817|UniProtKB=P21145 P21145 MAL PTHR22776:SF12 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MYELIN AND LYMPHOCYTE PROTEIN structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987;myelination#GO:0042552 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 membrane traffic protein#PC00150 HUMAN|HGNC=37287|UniProtKB=P0CV99 P0CV99 TSPY4 PTHR11875:SF12 TESTIS-SPECIFIC Y-ENCODED PROTEIN TESTIS-SPECIFIC Y-ENCODED PROTEIN 1-RELATED protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=30710|UniProtKB=Q96KC9 Q96KC9 CABS1 PTHR22810:SF1 TESTIS DEVELOPMENT PROTEIN NYD-SP26 CALCIUM-BINDING AND SPERMATID-SPECIFIC PROTEIN 1 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 developmental process involved in reproduction#GO:0003006;male gamete generation#GO:0048232;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;spermatogenesis#GO:0007283;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;multi-organism reproductive process#GO:0044703;multi-organism process#GO:0051704;multicellular organismal reproductive process#GO:0048609 envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;motile cilium#GO:0031514;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=9599|UniProtKB=O14684 O14684 PTGES PTHR10689:SF9 MICROSOMAL GLUTATHIONE S-TRANSFERASE 1 PROSTAGLANDIN E SYNTHASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;icosanoid metabolic process#GO:0006690;icosanoid biosynthetic process#GO:0046456;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;fatty acid derivative metabolic process#GO:1901568;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;prostaglandin metabolic process#GO:0006693;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;unsaturated fatty acid biosynthetic process#GO:0006636;oxidation-reduction process#GO:0055114;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transferase#PC00220 HUMAN|HGNC=21218|UniProtKB=O43598 O43598 DNPH1 PTHR15364:SF0 2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1 2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle catabolic process#GO:0046700;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cellular nitrogen compound catabolic process#GO:0044270;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 hydrolase#PC00121 HUMAN|HGNC=20532|UniProtKB=P60329 P60329 KRTAP12-4 PTHR23262:SF180 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 12-1-RELATED HUMAN|HGNC=23498|UniProtKB=Q86YQ8 Q86YQ8 CPNE8 PTHR10857:SF133 COPINE COPINE-8 calcium-dependent phospholipid binding#GO:0005544;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;binding#GO:0005488 response to metal ion#GO:0010038;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to inorganic substance#GO:0010035;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;response to chemical#GO:0042221 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=25512|UniProtKB=Q5VTL8 Q5VTL8 PRPF38B PTHR23142:SF2 UNCHARACTERIZED PRE-MRNA-SPLICING FACTOR 38B ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229 HUMAN|HGNC=9968|UniProtKB=O60673 O60673 REV3L PTHR45812:SF1 DNA POLYMERASE ZETA CATALYTIC SUBUNIT DNA POLYMERASE ZETA CATALYTIC SUBUNIT transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;DNA polymerase activity#GO:0034061;nucleotidyltransferase activity#GO:0016779 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;postreplication repair#GO:0006301;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular response to DNA damage stimulus#GO:0006974;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;translesion synthesis#GO:0019985;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;DNA synthesis involved in DNA repair#GO:0000731;aromatic compound biosynthetic process#GO:0019438;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259 DNA polymerase complex#GO:0042575;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed DNA polymerase#PC00018 HUMAN|HGNC=2366|UniProtKB=Q9UKG9 Q9UKG9 CROT PTHR22589:SF67 CARNITINE O-ACYLTRANSFERASE PEROXISOMAL CARNITINE O-OCTANOYLTRANSFERASE acyltransferase#PC00042 HUMAN|HGNC=20141|UniProtKB=O95848 O95848 NUDT14 PTHR11839:SF15 UDP/ADP-SUGAR PYROPHOSPHATASE URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT14 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 pyrophosphatase#PC00196 HUMAN|HGNC=19340|UniProtKB=P43356 P43356 MAGEA2B PTHR11736:SF74 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN 2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=11300|UniProtKB=P09132 P09132 SRP19 PTHR17453:SF1 SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;protein-containing complex assembly#GO:0065003;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;translation#GO:0006412;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein localization to organelle#GO:0033365;cellular protein metabolic process#GO:0044267;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;protein localization to endoplasmic reticulum#GO:0070972;macromolecule metabolic process#GO:0043170;protein localization to membrane#GO:0072657;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;peptide transport#GO:0015833;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;protein targeting to membrane#GO:0006612;peptide biosynthetic process#GO:0043043;cellular macromolecule localization#GO:0070727;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 primary active transporter#PC00068 HUMAN|HGNC=26441|UniProtKB=Q96N87 Q96N87 SLC6A18 PTHR11616:SF109 SODIUM/CHLORIDE DEPENDENT TRANSPORTER INACTIVE SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT3 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 HUMAN|HGNC=9282|UniProtKB=P62140 P62140 PPP1CB PTHR11668:SF472 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-BETA CATALYTIC SUBUNIT hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602;Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969 HUMAN|HGNC=21616|UniProtKB=Q68CZ2 Q68CZ2 TNS3 PTHR45734:SF5 TENSIN TENSIN-3 non-motor actin binding protein#PC00165 HUMAN|HGNC=277|UniProtKB=P35348 P35348 ADRA1A PTHR24248:SF16 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA-1A ADRENERGIC RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of lipase activity#GO:0060191;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;positive regulation of cytosolic calcium ion concentration#GO:0007204;regulation of phospholipase activity#GO:0010517;positive regulation of molecular function#GO:0044093;regulation of cAMP-mediated signaling#GO:0043949;regulation of catalytic activity#GO:0050790;cellular homeostasis#GO:0019725;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;ion homeostasis#GO:0050801;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;cellular divalent inorganic cation homeostasis#GO:0072503;intracellular signal transduction#GO:0035556;cell-cell signaling#GO:0007267;signaling#GO:0023052;positive regulation of phospholipase C activity#GO:0010863;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular cation homeostasis#GO:0030003;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;regulation of phospholipase C activity#GO:1900274;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;cellular chemical homeostasis#GO:0055082;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Alpha adrenergic receptor signaling pathway#P00002>Alpha1A/1B/1C#P00078 HUMAN|HGNC=10928|UniProtKB=O60669 O60669 SLC16A7 PTHR11360:SF25 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;monocarboxylic acid transmembrane transporter activity#GO:0008028;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;carboxylic acid transport#GO:0046942 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=3570|UniProtKB=O95573 O95573 ACSL3 PTHR43272:SF13 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 3 ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;neurogenesis#GO:0022008;sulfur compound metabolic process#GO:0006790;developmental process#GO:0032502;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;neuron differentiation#GO:0030182;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;long-chain fatty acid metabolic process#GO:0001676;cellular developmental process#GO:0048869;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;fatty acid derivative metabolic process#GO:1901568;monocarboxylic acid metabolic process#GO:0032787;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;organophosphate metabolic process#GO:0019637;generation of neurons#GO:0048699;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 lipid droplet#GO:0005811;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 ligase#PC00142 HUMAN|HGNC=12003|UniProtKB=O15350 O15350 TP73 PTHR11447:SF21 CELLULAR TUMOR ANTIGEN P53 TUMOR PROTEIN P73 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 P53-like transcription factor#PC00253 P53 pathway feedback loops 1#P04392>p53#P04539;P53 pathway feedback loops 1#P04392>p73#G04686;p53 pathway feedback loops 2#P04398>p53#P04668;Huntington disease#P00029>p53#P00797;p53 pathway#P00059>p53#G04702;p53 pathway by glucose deprivation#P04397>p53#P04640;p53 pathway#P00059>p53#P01485 HUMAN|HGNC=34435|UniProtKB=Q2WGJ6 Q2WGJ6 KLHL38 PTHR24412:SF462 KELCH PROTEIN KELCH-LIKE PROTEIN 38 scaffold/adaptor protein#PC00226 HUMAN|HGNC=12485|UniProtKB=P63279 P63279 UBE2I PTHR24067:SF280 UBIQUITIN-CONJUGATING ENZYME E2 SUMO-CONJUGATING ENZYME UBC9 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=26225|UniProtKB=Q8IV53 Q8IV53 DENND1C PTHR13196:SF25 DENN DOMAIN-CONTAINING DENN DOMAIN-CONTAINING PROTEIN 1C binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;small GTPase binding#GO:0031267;guanyl-nucleotide exchange factor activity#GO:0005085;Rab GTPase binding#GO:0017137;Ras GTPase binding#GO:0017016;Ras guanyl-nucleotide exchange factor activity#GO:0005088;molecular function regulator#GO:0098772;protein binding#GO:0005515;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;Rab guanyl-nucleotide exchange factor activity#GO:0017112 endosomal transport#GO:0016197;cellular localization#GO:0051641;membrane organization#GO:0061024;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endocytic recycling#GO:0032456;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28841|UniProtKB=O60811 O60811 PRAMEF2 PTHR14224:SF98 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=24496|UniProtKB=Q6NW34 Q6NW34 NEPRO PTHR34761:SF1 NUCLEOLUS AND NEURAL PROGENITOR PROTEIN NUCLEOLUS AND NEURAL PROGENITOR PROTEIN regulation of cell communication#GO:0010646;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;regulation of Notch signaling pathway#GO:0008593;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;Notch signaling pathway#GO:0007219 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=11363|UniProtKB=P52630 P52630 STAT2 PTHR11801:SF41 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 response to external biotic stimulus#GO:0043207;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;defense response#GO:0006952;organic substance metabolic process#GO:0071704;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;response to nitrogen compound#GO:1901698;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;type I interferon signaling pathway#GO:0060337;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;RNA metabolic process#GO:0016070;response to peptide hormone#GO:0043434;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;response to peptide#GO:1901652;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;cytokine-mediated signaling pathway#GO:0019221;regulation of gene expression#GO:0010468;signaling#GO:0023052;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;response to type I interferon#GO:0034340;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to hormone#GO:0009725;regulation of cellular biosynthetic process#GO:0031326;receptor signaling pathway via STAT#GO:0097696;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>STAT#P01173;JAK/STAT signaling pathway#P00038>STAT#P01027;Interleukin signaling pathway#P00036>STAT#P00996;EGF receptor signaling pathway#P00018>STAT#P00561 HUMAN|HGNC=11764|UniProtKB=P01266 P01266 TG PTHR14093:SF19 HLA CLASS II GAMMA CHAIN THYROGLOBULIN cellular aromatic compound metabolic process#GO:0006725;organic hydroxy compound metabolic process#GO:1901615;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;cellular modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 scaffold/adaptor protein#PC00226 HUMAN|HGNC=14758|UniProtKB=Q8NH08 Q8NH08 OR10AC1 PTHR26453:SF638 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10AC1 transmembrane signal receptor#PC00197 HUMAN|HGNC=11284|UniProtKB=P18405 P18405 SRD5A1 PTHR10556:SF49 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 1 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;lipid biosynthetic process#GO:0008610;organic cyclic compound biosynthetic process#GO:1901362;steroid biosynthetic process#GO:0006694;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 dehydrogenase#PC00092 HUMAN|HGNC=5732|UniProtKB=P04430 P04430 IGKV1-16 PTHR23267:SF384 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-16-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=12029|UniProtKB=P01848 P01848 TRAC PTHR19433:SF72 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA CHAIN MC.7.G5-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=28469|UniProtKB=Q9BV20 Q9BV20 MRI1 PTHR43475:SF1 METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE isomerase activity#GO:0016853;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;sulfur compound metabolic process#GO:0006790;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 isomerase#PC00135 HUMAN|HGNC=26425|UniProtKB=Q8N4P2 Q8N4P2 TTC30B PTHR20931:SF6 UNCHARACTERIZED TETRATRICOPEPTIDE REPEAT PROTEIN 30B protein-containing complex binding#GO:0044877;binding#GO:0005488 microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic microtubule#GO:0005881;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;microtubule organizing center#GO:0005815;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;cytoskeleton#GO:0005856;axonemal microtubule#GO:0005879;plasma membrane#GO:0005886 HUMAN|HGNC=9875|UniProtKB=Q13972 Q13972 RASGRF1 PTHR23113:SF193 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR 1 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=2989|UniProtKB=Q8IZD9 Q8IZD9 DOCK3 PTHR45653:SF4 DEDICATOR OF CYTOKINESIS DEDICATOR OF CYTOKINESIS PROTEIN 3 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=12022|UniProtKB=P13693 P13693 TPT1 PTHR11991:SF9 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TPT1-LIKE PROTEIN-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=27916|UniProtKB=Q8NDY8 Q8NDY8 TMEM52 PTHR33955:SF2 TRANSMEMBRANE PROTEIN 52 TRANSMEMBRANE PROTEIN 52 HUMAN|HGNC=11162|UniProtKB=P62306 P62306 SNRPF PTHR11021:SF9 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F SMALL NUCLEAR RIBONUCLEOPROTEIN F nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;U1 snRNP#GO:0005685;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=11766|UniProtKB=P01137 P01137 TGFB1 PTHR11848:SF125 TGF-BETA FAMILY TRANSFORMING GROWTH FACTOR BETA-1 PROPROTEIN receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;transforming growth factor beta receptor signaling pathway#GO:0007179;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;cellular response to BMP stimulus#GO:0071773;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;response to BMP#GO:0071772;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 TGF-beta signaling pathway#P00052>TGFbeta#P01286;Gonadotropin-releasing hormone receptor pathway#P06664>TGFbeta#P06778 HUMAN|HGNC=20429|UniProtKB=Q8N7Q3 Q8N7Q3 ZNF676 PTHR24384:SF112 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 676 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=4952|UniProtKB=P13762 P13762 HLA-DRB4 PTHR19944:SF84 MHC CLASS II-RELATED HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR BETA 3 CHAIN-RELATED major histocompatibility complex protein#PC00149 HUMAN|HGNC=30075|UniProtKB=O15318 O15318 POLR3G PTHR15367:SF3 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC7 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;chromatin#GO:0000785;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;RNA polymerase III complex#GO:0005666;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-directed RNA polymerase#PC00019 HUMAN|HGNC=19137|UniProtKB=Q5ZPR3 Q5ZPR3 CD276 PTHR24100:SF2 BUTYROPHILIN CD276 ANTIGEN immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=11773|UniProtKB=P37173 P37173 TGFBR2 PTHR23255:SF55 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II TGF-BETA RECEPTOR TYPE-2 signaling receptor activity#GO:0038023;SMAD binding#GO:0046332;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cytokine binding#GO:0019955;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;growth factor binding#GO:0019838;protein serine/threonine kinase activity#GO:0004674;molecular transducer activity#GO:0060089;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;activin binding#GO:0048185;catalytic activity, acting on a protein#GO:0140096;cytokine receptor binding#GO:0005126 heart development#GO:0007507;signal transduction#GO:0007165;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;developmental process#GO:0032502;protein modification process#GO:0036211;transforming growth factor beta receptor signaling pathway#GO:0007179;phosphorus metabolic process#GO:0006793;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;response to endogenous stimulus#GO:0009719;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular process#GO:0009987;activin receptor signaling pathway#GO:0032924;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 membrane protein complex#GO:0098796;catalytic complex#GO:1902494;transferase complex#GO:1990234;plasma membrane protein complex#GO:0098797;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277 HUMAN|HGNC=9545|UniProtKB=P28062 P28062 PSMB8 PTHR11599:SF53 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-8 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 HUMAN|HGNC=16068|UniProtKB=O95613 O95613 PCNT PTHR44981:SF3 PERICENTRIN-LIKE PROTEIN, ISOFORM F PERICENTRIN HUMAN|HGNC=16437|UniProtKB=Q9BX51 Q9BX51 GGTLC1 PTHR45027:SF4 PUTATIVE GLUTATHIONE HYDROLASE LIGHT CHAIN GLUTATHIONE HYDROLASE LIGHT CHAIN 1 hydrolase#PC00121 HUMAN|HGNC=10249|UniProtKB=Q9Y6N7 Q9Y6N7 ROBO1 PTHR12231:SF243 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN ROUNDABOUT HOMOLOG 1 Axon guidance mediated by Slit/Robo#P00008>Robo#P00348 HUMAN|HGNC=17027|UniProtKB=Q8TF71 Q8TF71 SLC16A10 PTHR11360:SF119 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 10 intrinsic component of membrane#GO:0031224;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020 transporter#PC00227 HUMAN|HGNC=13909|UniProtKB=Q9NQL9 Q9NQL9 DMRT3 PTHR12322:SF53 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;reproductive process#GO:0022414;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;sex differentiation#GO:0007548;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;reproduction#GO:0000003;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=40048|UniProtKB=F5H4A9 F5H4A9 C3orf80 PTHR38505:SF1 HYPOTHETICAL PROTEIN LOC100362176 HYPOTHETICAL PROTEIN LOC100362176 HUMAN|HGNC=21497|UniProtKB=Q9H845 Q9H845 ACAD9 PTHR43884:SF9 ACYL-COA DEHYDROGENASE COMPLEX I ASSEMBLY FACTOR ACAD9, MITOCHONDRIAL carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;purine nucleotide binding#GO:0017076;acyl-CoA dehydrogenase activity#GO:0003995;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;amide binding#GO:0033218;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 HUMAN|HGNC=11063|UniProtKB=Q01650 Q01650 SLC7A5 PTHR11785:SF315 AMINO ACID TRANSPORTER L-TYPE AMINO ACID TRANSPORTER 1-LIKE PROTEIN IMAA-RELATED inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;neutral amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;organic acid transmembrane transporter activity#GO:0005342;L-amino acid transmembrane transporter activity#GO:0015179;ion transmembrane transporter activity#GO:0015075;amino acid transmembrane transporter activity#GO:0015171;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;organic anion transport#GO:0015711;organic acid transport#GO:0015849;ion transport#GO:0006811;transport#GO:0006810;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;carboxylic acid transmembrane transport#GO:1905039;anion transmembrane transport#GO:0098656;localization#GO:0051179;organic substance transport#GO:0071702;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;anion transport#GO:0006820;organic acid transmembrane transport#GO:1903825 transporter#PC00227 HUMAN|HGNC=12607|UniProtKB=O94782 O94782 USP1 PTHR24006:SF663 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 1 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=31963|UniProtKB=A5LHX3 A5LHX3 PSMB11 PTHR11599:SF48 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA TYPE-11 hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protease#PC00190 HUMAN|HGNC=29501|UniProtKB=P81274 P81274 GPSM2 PTHR45954:SF3 LD33695P G-PROTEIN-SIGNALING MODULATOR 2 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>AGS3#P00715;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>AGS3#P00739 HUMAN|HGNC=15452|UniProtKB=Q9H4A6 Q9H4A6 GOLPH3 PTHR12704:SF3 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3 lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;Golgi vesicle budding#GO:0048194;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;endomembrane system organization#GO:0010256;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;Golgi to plasma membrane transport#GO:0006893;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;vesicle organization#GO:0016050;protein localization to plasma membrane#GO:0072659;vesicle-mediated transport to the plasma membrane#GO:0098876;Golgi organization#GO:0007030;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;Golgi to plasma membrane protein transport#GO:0043001;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;protein transport#GO:0015031 trans-Golgi network#GO:0005802;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;plasma membrane#GO:0005886 HUMAN|HGNC=917|UniProtKB=O43825 O43825 B3GALT2 PTHR11214:SF19 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 2 transferase activity, transferring hexosyl groups#GO:0016758;acetylglucosaminyltransferase activity#GO:0008375;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=16834|UniProtKB=Q16612 Q16612 NREP PTHR17102:SF4 NEURONAL REGENERATION-RELATED PROTEIN NEURONAL REGENERATION-RELATED PROTEIN signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;response to growth factor#GO:0070848;developmental process#GO:0032502;regulation of signaling#GO:0023051;transforming growth factor beta receptor signaling pathway#GO:0007179;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;neuron differentiation#GO:0030182;regulation of cellular response to growth factor stimulus#GO:0090287;signaling#GO:0023052;regulation of cellular response to transforming growth factor beta stimulus#GO:1903844;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;regulation of cell development#GO:0060284;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;regulation of neuron differentiation#GO:0045664;cell development#GO:0048468;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to stress#GO:0006950;response to wounding#GO:0009611;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;cellular response to growth factor stimulus#GO:0071363;regulation of nervous system development#GO:0051960;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;regulation of transforming growth factor beta receptor signaling pathway#GO:0017015;neuron development#GO:0048666;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16870|UniProtKB=Q14680 Q14680 MELK PTHR24343:SF121 SERINE/THREONINE KINASE MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=26633|UniProtKB=Q7Z7L1 Q7Z7L1 SLFN11 PTHR12155:SF45 SCHLAFEN SCHLAFEN FAMILY MEMBER 11 tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 response to virus#GO:0009615;response to external biotic stimulus#GO:0043207;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419;defense response to virus#GO:0051607;defense response#GO:0006952;immune effector process#GO:0002252 HUMAN|HGNC=10912|UniProtKB=P55017 P55017 SLC12A3 PTHR11827:SF9 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 3 inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;sodium:chloride symporter activity#GO:0015378;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic anion transmembrane transporter activity#GO:0015103;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 inorganic ion homeostasis#GO:0098771;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;chloride transmembrane transport#GO:1902476;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;inorganic anion transport#GO:0015698;potassium ion transport#GO:0006813;regulation of anatomical structure size#GO:0090066;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;chloride transport#GO:0006821;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cation homeostasis#GO:0055080;monovalent inorganic cation homeostasis#GO:0055067;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;regulation of cellular component size#GO:0032535;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;sodium ion transport#GO:0006814;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;metal ion homeostasis#GO:0055065;sodium ion transmembrane transport#GO:0035725 secondary carrier transporter#PC00258 HUMAN|HGNC=10624|UniProtKB=O15444 O15444 CCL25 PTHR12015:SF70 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 25 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 HUMAN|HGNC=26099|UniProtKB=A1A4S6 A1A4S6 ARHGAP10 PTHR12552:SF5 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN 10 GTPase activity#GO:0003924;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257 Integrin signalling pathway#P00034>GRAF#P00926;PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=26536|UniProtKB=Q8NEE8 Q8NEE8 TTC16 PTHR45153:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 16 TETRATRICOPEPTIDE REPEAT PROTEIN 16 HUMAN|HGNC=18700|UniProtKB=Q9NQI0 Q9NQI0 DDX4 PTHR47958:SF11 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX4-RELATED catalytic activity, acting on RNA#GO:0140098;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;helicase activity#GO:0004386;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 cell differentiation#GO:0030154;cellular developmental process#GO:0048869;gamete generation#GO:0007276;reproduction#GO:0000003;multicellular organism reproduction#GO:0032504;sexual reproduction#GO:0019953;developmental process#GO:0032502;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;cellular process#GO:0009987;multi-organism reproductive process#GO:0044703;multi-organism process#GO:0051704;multicellular organismal reproductive process#GO:0048609 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 HUMAN|HGNC=12243|UniProtKB=P04435 P04435 TRBV7-9 PTHR23268:SF20 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 7-9 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=19275|UniProtKB=Q5GAN6 Q5GAN6 RNASE10 PTHR11437:SF10 RIBONUCLEASE INACTIVE RIBONUCLEASE-LIKE PROTEIN 10 HUMAN|HGNC=2716|UniProtKB=O95865 O95865 DDAH2 PTHR12737:SF16 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE N(G),N(G)-DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 2 amino acid binding#GO:0016597;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;carboxylic acid binding#GO:0031406;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;biosynthetic process#GO:0009058;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;regulation of reactive oxygen species metabolic process#GO:2000377;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of cellular biosynthetic process#GO:0031326;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;regulation of metabolic process#GO:0019222;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323 hydrolase#PC00121 HUMAN|HGNC=19221|UniProtKB=Q9Y6I7 Q9Y6I7 WSB1 PTHR15622:SF12 WD40 REPEAT PROTEIN WD REPEAT AND SOCS BOX-CONTAINING PROTEIN 1 HUMAN|HGNC=4930|UniProtKB=P10074 P10074 ZBTB48 PTHR24390:SF139 ZINC FINGER PROTEIN TELOMERE ZINC FINGER-ASSOCIATED PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=26506|UniProtKB=Q96MI6 Q96MI6 PPM1M PTHR13832:SF236 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1M hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=11180|UniProtKB=P04179 P04179 SOD2 PTHR11404:SF6 SUPEROXIDE DISMUTASE 2 SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914 oxidoreductase#PC00176 HUMAN|HGNC=26672|UniProtKB=Q6ZUB1 Q6ZUB1 SPATA31E1 PTHR21859:SF48 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31E1 HUMAN|HGNC=6874|UniProtKB=P53778 P53778 MAPK12 PTHR24055:SF146 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE 12 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;gene expression#GO:0010467;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;intracellular signal transduction#GO:0035556;signaling#GO:0023052;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Gonadotropin-releasing hormone receptor pathway#P06664>p38#P06831;p38 MAPK pathway#P05918>p38gamma#P06015;TGF-beta signaling pathway#P00052>P38#P01275;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;EGF receptor signaling pathway#P00018>p38#P00562;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Ras Pathway#P04393>p38#P04558;B cell activation#P00010>p38#P00384;Oxidative stress response#P00046>p38#P01135;FGF signaling pathway#P00021>p38#P00644;Parkinson disease#P00049>SAPK#P01219 HUMAN|HGNC=3394|UniProtKB=P54753 P54753 EPHB3 PTHR24416:SF120 TYROSINE-PROTEIN KINASE RECEPTOR EPHRIN TYPE-B RECEPTOR 3 signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;positive regulation of cellular metabolic process#GO:0031325;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;regulation of molecular function#GO:0065009;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;taxis#GO:0042330;regulation of cellular metabolic process#GO:0031323;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;axon guidance#GO:0007411;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;regulation of transferase activity#GO:0051338 receptor complex#GO:0043235;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;integral component of membrane#GO:0016021;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Angiogenesis#P00005>EphR#P00212 HUMAN|HGNC=6763|UniProtKB=Q13257 Q13257 MAD2L1 PTHR11842:SF13 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A negative regulation of sister chromatid segregation#GO:0033046;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of mitotic sister chromatid segregation#GO:0033047;negative regulation of cellular component organization#GO:0051129;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;mitotic cell cycle phase transition#GO:0044772;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;negative regulation of organelle organization#GO:0010639;mitotic spindle assembly checkpoint#GO:0007094;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;mitotic cell cycle checkpoint#GO:0007093;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;metaphase/anaphase transition of cell cycle#GO:0044784;negative regulation of chromosome separation#GO:1905819;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;cell cycle#GO:0007049;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;nuclear lumen#GO:0031981 HUMAN|HGNC=17941|UniProtKB=Q9P121 Q9P121 NTM PTHR42757:SF9 IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED NEUROTRIMIN immunoglobulin#PC00123 HUMAN|HGNC=634|UniProtKB=P41181 P41181 AQP2 PTHR19139:SF45 AQUAPORIN TRANSPORTER AQUAPORIN-2 inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 intrinsic component of membrane#GO:0031224;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;apical part of cell#GO:0045177 transporter#PC00227 HUMAN|HGNC=11476|UniProtKB=O15260 O15260 SURF4 PTHR23427:SF13 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 4 chaperone#PC00072 HUMAN|HGNC=5970|UniProtKB=P29460 P29460 IL12B PTHR23036:SF156 CYTOKINE RECEPTOR INTERLEUKIN-12 SUBUNIT BETA signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=17367|UniProtKB=Q9NWB7 Q9NWB7 IFT57 PTHR16011:SF0 IFT57/HIPPI INTRAFLAGELLAR TRANSPORT PROTEIN 57 HOMOLOG vesicle targeting, to, from or within Golgi#GO:0048199;non-motile cilium assembly#GO:1905515;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;centriole#GO:0005814;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;centrosome#GO:0005813;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intraciliary transport particle B#GO:0030992;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 structural protein#PC00211 Huntington disease#P00029>Hip-12#P00763;Huntington disease#P00029>Hippi#P00794 HUMAN|HGNC=30627|UniProtKB=Q8TCT7 Q8TCT7 SPPL2B PTHR12174:SF39 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 2B hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 membrane protein proteolysis#GO:0033619;nitrogen compound metabolic process#GO:0006807;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;primary metabolic process#GO:0044238 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;lysosome#GO:0005764;intracellular#GO:0005622;cytoplasmic side of membrane#GO:0098562;leaflet of membrane bilayer#GO:0097478;intracellular vesicle#GO:0097708;vacuolar membrane#GO:0005774;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell periphery#GO:0071944;membrane#GO:0016020;lytic vacuole#GO:0000323;side of membrane#GO:0098552;whole membrane#GO:0098805;intrinsic component of endoplasmic reticulum membrane#GO:0031227;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;Golgi-associated vesicle membrane#GO:0030660;endomembrane system#GO:0012505;integral component of endoplasmic reticulum membrane#GO:0030176;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 aspartic protease#PC00053 HUMAN|HGNC=11140|UniProtKB=Q16143 Q16143 SNCB PTHR13820:SF4 SYNUCLEIN BETA-SYNUCLEIN cation binding#GO:0043169;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488;transition metal ion binding#GO:0046914 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;regulation of neuron death#GO:1901214;membrane organization#GO:0061024;transport#GO:0006810;neuron death#GO:0070997;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;cell death#GO:0008219;synaptic signaling#GO:0099536;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of cell death#GO:0010941;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;axon#GO:0030424;cytoplasm#GO:0005737;axon terminus#GO:0043679;cell body#GO:0044297;intracellular#GO:0005622;neuron projection#GO:0043005;neuron projection terminus#GO:0044306;plasma membrane region#GO:0098590;distal axon#GO:0150034;cell projection#GO:0042995;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Parkinson disease#P00049>beta-Synuclein#P01217 HUMAN|HGNC=2385|UniProtKB=Q49AN0 Q49AN0 CRY2 PTHR11455:SF15 CRYPTOCHROME CRYPTOCHROME-2 nucleotide binding#GO:0000166;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;response to abiotic stimulus#GO:0009628;organic substance metabolic process#GO:0071704;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;circadian regulation of gene expression#GO:0032922;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of circadian rhythm#GO:0042752;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;response to radiation#GO:0009314;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;response to light stimulus#GO:0009416;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to external stimulus#GO:0009605;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA photolyase#PC00014 Circadian clock system#P00015>Cry#P00505;Circadian clock system#P00015>cry#G01497;Circadian clock system#P00015>cry#G01501 HUMAN|HGNC=13608|UniProtKB=Q9UKT8 Q9UKT8 FBXW2 PTHR44436:SF1 F-BOX/WD REPEAT-CONTAINING PROTEIN 2 F-BOX/WD REPEAT-CONTAINING PROTEIN 2 HUMAN|HGNC=14992|UniProtKB=Q5JRS4 Q5JRS4 OR10J3 PTHR26451:SF28 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 10J3 HUMAN|HGNC=23206|UniProtKB=Q86TE4 Q86TE4 LUZP2 PTHR22414:SF0 UNCHARACTERIZED LEUCINE ZIPPER PROTEIN 2 HUMAN|HGNC=50289|UniProtKB=H0YM25 H0YM25 GOLGA6L22 PTHR23143:SF20 TRICHOHYALIN-RELATED GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 1-RELATED actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=24753|UniProtKB=Q17RG1 Q17RG1 KCTD19 PTHR14499:SF20 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD19 scaffold/adaptor protein#PC00226 HUMAN|HGNC=6863|UniProtKB=Q92918 Q92918 MAP4K1 PTHR48012:SF15 STERILE20-LIKE KINASE, ISOFORM B-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 1 MAP kinase activity#GO:0004707;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;MAP kinase kinase activity#GO:0004708;protein kinase activity#GO:0004672 Apoptosis signaling pathway#P00006>GCKR#P00311;Gonadotropin-releasing hormone receptor pathway#P06664>MAP4Ks#P06861;Apoptosis signaling pathway#P00006>GCK#P00268 HUMAN|HGNC=25476|UniProtKB=Q9NWD8 Q9NWD8 TMEM248 PTHR16002:SF5 TRANSMEMBRANE PROTEIN 248-LIKE TRANSMEMBRANE PROTEIN 248 HUMAN|HGNC=23081|UniProtKB=Q8TEB9 Q8TEB9 RHBDD1 PTHR43066:SF14 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 4 serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 serine protease#PC00203 HUMAN|HGNC=11585|UniProtKB=O60907 O60907 TBL1X PTHR22846:SF52 WD40 REPEAT PROTEIN F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;protein deacetylation#GO:0006476;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 Wnt signaling pathway#P00057>Ebi#P01453 HUMAN|HGNC=4385|UniProtKB=P04899 P04899 GNAI2 PTHR10218:SF73 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-2 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;nucleoside-triphosphatase activity#GO:0017111;G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102 regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 Enkephalin release#P05913>G-Protein (i)#P05974;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Galphai#P00828;Opioid proenkephalin pathway#P05915>G-protein#P05994;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Dopamine receptor mediated signaling pathway#P05912>Gialpha#P05958;Gonadotropin-releasing hormone receptor pathway#P06664>gnai#P06807;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Opioid prodynorphin pathway#P05916>G-protein#P06002;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047 HUMAN|HGNC=18732|UniProtKB=Q9P2J3 Q9P2J3 KLHL9 PTHR45632:SF11 LD33804P KELCH-LIKE PROTEIN 9 HUMAN|HGNC=32222|UniProtKB=P0C5J1 P0C5J1 FAM86B2 PTHR14614:SF128 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN N-METHYLTRANSFERASE FAM86B1-RELATED HUMAN|HGNC=26938|UniProtKB=Q53FT3 Q53FT3 HIKESHI PTHR12925:SF0 HIKESHI FAMILY MEMBER PROTEIN HIKESHI transporter activity#GO:0005215 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;establishment of protein localization to organelle#GO:0072594;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;protein import into nucleus#GO:0006606;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;import into nucleus#GO:0051170 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=16039|UniProtKB=Q9BY76 Q9BY76 ANGPTL4 PTHR19143:SF256 FIBRINOGEN/TENASCIN/ANGIOPOEITIN ANGIOPOIETIN-RELATED PROTEIN 4 molecular function regulator#GO:0098772;enzyme inhibitor activity#GO:0004857;catalytic activity#GO:0003824;enzyme regulator activity#GO:0030234 biological regulation#GO:0065007;lipid homeostasis#GO:0055088;homeostatic process#GO:0042592;triglyceride homeostasis#GO:0070328;chemical homeostasis#GO:0048878;regulation of biological quality#GO:0065008 extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;collagen-containing extracellular matrix#GO:0062023;extracellular space#GO:0005615;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=17955|UniProtKB=O43504 O43504 LAMTOR5 PTHR13342:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR5 RAGULATOR COMPLEX PROTEIN LAMTOR5 GTPase binding#GO:0051020;enzyme binding#GO:0019899;molecular function regulator#GO:0098772;protein binding#GO:0005515;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;TOR signaling#GO:0031929;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;TORC1 signaling#GO:0038202;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;lytic vacuole#GO:0000323;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;lysosome#GO:0005764;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane raft#GO:0045121;membrane microdomain#GO:0098857;membrane region#GO:0098589;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=18958|UniProtKB=Q8TDF6 Q8TDF6 RASGRP4 PTHR23113:SF157 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 4 guanyl-nucleotide exchange factor#PC00113 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>CalDAG-GEF#P00736 HUMAN|HGNC=27846|UniProtKB=P0DKV0 P0DKV0 SPATA31C1 PTHR21859:SF44 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31C1-RELATED HUMAN|HGNC=17158|UniProtKB=Q8IV08 Q8IV08 PLD3 PTHR10185:SF16 PHOSPHOLIPASE D - RELATED 5'-3' EXONUCLEASE PLD3 phospholipase#PC00186 HUMAN|HGNC=27091|UniProtKB=A6NKX4 A6NKX4 SLC22A31 PTHR24064:SF196 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 31-RELATED secondary carrier transporter#PC00258 HUMAN|HGNC=19077|UniProtKB=O14931 O14931 NCR3 PTHR47904:SF1 NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3 NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3 immune response-regulating signaling pathway#GO:0002764;response to external biotic stimulus#GO:0043207;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;lymphocyte mediated immunity#GO:0002449;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;response to biotic stimulus#GO:0009607;positive regulation of leukocyte mediated immunity#GO:0002705;immune response-activating signal transduction#GO:0002757;regulation of lymphocyte mediated immunity#GO:0002706;innate immune response#GO:0045087;regulation of immune system process#GO:0002682;positive regulation of immune effector process#GO:0002699;defense response#GO:0006952;positive regulation of biological process#GO:0048518;signaling#GO:0023052;immune effector process#GO:0002252;leukocyte activation#GO:0045321;immune response-regulating cell surface receptor signaling pathway#GO:0002768;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;lymphocyte activation#GO:0046649;immune response#GO:0006955;positive regulation of innate immune response#GO:0045089;positive regulation of response to external stimulus#GO:0032103;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;leukocyte mediated immunity#GO:0002443;regulation of response to stress#GO:0080134;positive regulation of immune system process#GO:0002684;cell communication#GO:0007154;cellular process#GO:0009987;positive regulation of lymphocyte mediated immunity#GO:0002708;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;regulation of response to biotic stimulus#GO:0002831;regulation of innate immune response#GO:0045088;immune system process#GO:0002376;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;regulation of immune effector process#GO:0002697;response to stress#GO:0006950;defense response to other organism#GO:0098542;response to other organism#GO:0051707;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of defense response#GO:0031347;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;immune response-activating cell surface receptor signaling pathway#GO:0002429;positive regulation of defense response#GO:0031349;positive regulation of response to biotic stimulus#GO:0002833 HUMAN|HGNC=33576|UniProtKB=Q8N8J0 Q8N8J0 PI4KAP1 PTHR10048:SF15 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE ALPHA-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;cell communication#GO:0007154;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;organophosphate metabolic process#GO:0019637;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;phosphatidylinositol phosphorylation#GO:0046854;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular#GO:0005622;plasma membrane#GO:0005886 kinase#PC00137 HUMAN|HGNC=1340|UniProtKB=Q86T20 Q86T20 SMIM29 PTHR47730:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 29 SMALL INTEGRAL MEMBRANE PROTEIN 29 HUMAN|HGNC=37100|UniProtKB=A6NFT4 A6NFT4 CFAP73 PTHR21683:SF9 UNCHARACTERIZED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 73 HUMAN|HGNC=21483|UniProtKB=Q5T1Q4 Q5T1Q4 SLC35F1 PTHR14233:SF10 DUF914-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F1 HUMAN|HGNC=32565|UniProtKB=A6ND01 A6ND01 IZUMO1R PTHR10517:SF10 FOLATE RECEPTOR SPERM-EGG FUSION PROTEIN JUNO signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell recognition#GO:0008037;plasma membrane fusion#GO:0045026;fertilization#GO:0009566;membrane organization#GO:0061024;cellular process involved in reproduction in multicellular organism#GO:0022412;multicellular organism reproduction#GO:0032504;single fertilization#GO:0007338;biological adhesion#GO:0022610;cellular component organization#GO:0016043;cell adhesion#GO:0007155;cellular process#GO:0009987;multi-organism process#GO:0051704;cell-cell recognition#GO:0009988;cellular component organization or biogenesis#GO:0071840;reproduction#GO:0000003;membrane fusion#GO:0061025;sexual reproduction#GO:0019953;reproductive process#GO:0022414;multicellular organismal process#GO:0032501;sperm-egg recognition#GO:0035036;multi-organism reproductive process#GO:0044703 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;anchored component of plasma membrane#GO:0046658;intrinsic component of membrane#GO:0031224;intrinsic component of plasma membrane#GO:0031226;anchored component of membrane#GO:0031225;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 HUMAN|HGNC=4412|UniProtKB=O14610 O14610 GNGT2 PTHR13809:SF28 GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-T2 protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 membrane protein complex#GO:0098796;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;catalytic complex#GO:1902494;plasma membrane protein complex#GO:0098797;extrinsic component of plasma membrane#GO:0019897;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886 heterotrimeric G-protein#PC00117 5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Ggamma#P00751;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Opioid prodynorphin pathway#P05916>G-protein#P06002;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GIRK#P00743;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;PI3 kinase pathway#P00048>Gbetagamma#P01188;Endogenous cannabinoid signaling#P05730>Ggamma#P05744;GABA-B receptor II signaling#P05731>Ggamma#P05754;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Ggamma#P05929;Enkephalin release#P05913>G-Protein (s)#P05977;Opioid proenkephalin pathway#P05915>G-protein#P05994;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ggamma#P00726;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Ggamma#P00721 HUMAN|HGNC=21115|UniProtKB=Q6P444 Q6P444 MTFR2 PTHR14215:SF2 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 2 cellular component organization or biogenesis#GO:0071840;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organelle organization#GO:0006996;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;organelle fission#GO:0048285;cellular metabolic process#GO:0044237;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial fission#GO:0000266;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=4161|UniProtKB=Q14392 Q14392 LRRC32 PTHR24373:SF354 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC32 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=8755|UniProtKB=Q9Y5K3 Q9Y5K3 PCYT1B PTHR10739:SF20 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE B cation binding#GO:0043169;transferase activity#GO:0016740;phosphatidylcholine binding#GO:0031210;binding#GO:0005488;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid binding#GO:0008289;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543 transferase#PC00220 HUMAN|HGNC=29959|UniProtKB=Q6PID6 Q6PID6 TTC33 PTHR15544:SF0 OSMOSIS RESPONSIVE FACTOR TETRATRICOPEPTIDE REPEAT PROTEIN 33 HUMAN|HGNC=30179|UniProtKB=A6NKF1 A6NKF1 SAC3D1 PTHR12436:SF3 80 KDA MCM3-ASSOCIATED PROTEIN SAC3 DOMAIN-CONTAINING PROTEIN 1 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;ribonucleoprotein complex localization#GO:0071166;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;protein-containing complex localization#GO:0031503 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=9855|UniProtKB=P62834 P62834 RAP1A PTHR24070:SF395 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1A GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;Ras protein signal transduction#GO:0007265;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;neurotransmitter secretion#GO:0007269;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of transport#GO:0051051;response to organonitrogen compound#GO:0010243;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;response to nitrogen compound#GO:1901698;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;regulation of trans-synaptic signaling#GO:0099177;export from cell#GO:0140352;vesicle fusion#GO:0006906;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;regulation of signaling#GO:0023051;transport#GO:0006810;cellular response to nitrogen compound#GO:1901699;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;neurotransmitter transport#GO:0006836;cellular response to organic cyclic compound#GO:0071407;signal release#GO:0023061;vesicle organization#GO:0016050;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;synaptic vesicle exocytosis#GO:0016079;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;response to chemical#GO:0042221;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 HUMAN|HGNC=10902|UniProtKB=Q13239 Q13239 SLA PTHR24418:SF293 TYROSINE-PROTEIN KINASE SRC-LIKE-ADAPTER protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;signaling receptor binding#GO:0005102;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;lysosome localization#GO:0032418;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;secretion#GO:0046903;regulation of secretion#GO:0051046;innate immune response#GO:0045087;positive regulation of immune effector process#GO:0002699;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;leukocyte activation#GO:0045321;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of cellular localization#GO:0060341;cell activation involved in immune response#GO:0002263;exocytic process#GO:0140029;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;exocytosis#GO:0006887;leukocyte activation involved in immune response#GO:0002366;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;locomotion#GO:0040011;export from cell#GO:0140352;taxis#GO:0042330;vesicle fusion#GO:0006906;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;biological adhesion#GO:0022610;developmental process#GO:0032502;transport#GO:0006810;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;regulation of transport#GO:0051049;protein autophosphorylation#GO:0046777;vesicle organization#GO:0016050;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;immune effector process#GO:0002252;chemotaxis#GO:0006935;metabolic process#GO:0008152;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;immune system process#GO:0002376;response to stimulus#GO:0050896;regulation of immune effector process#GO:0002697;response to external stimulus#GO:0009605;regulation of leukocyte activation#GO:0002694;membrane fusion#GO:0061025;peptidyl-tyrosine modification#GO:0018212;response to chemical#GO:0042221;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;establishment of localization in cell#GO:0051649 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 HUMAN|HGNC=21575|UniProtKB=Q8N157 Q8N157 AHI1 PTHR44499:SF1 JOUBERIN JOUBERIN HUMAN|HGNC=7453|UniProtKB=Q9Y217 Q9Y217 MTMR6 PTHR10807:SF34 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 6 hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;dephosphorylation#GO:0016311;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=28079|UniProtKB=Q86UK7 Q86UK7 ZNF598 PTHR22938:SF0 ZINC FINGER PROTEIN 598 E3 UBIQUITIN-PROTEIN LIGASE ZNF598 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=2769|UniProtKB=O43583 O43583 DENR PTHR12789:SF0 DENSITY-REGULATED PROTEIN HOMOLOG DENSITY-REGULATED PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component biogenesis#GO:0044085;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cytoplasmic translation#GO:0002181;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;cytoplasmic translational initiation#GO:0002183;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;ribonucleoprotein complex biogenesis#GO:0022613;translational initiation#GO:0006413;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603 translation initiation factor#PC00224 HUMAN|HGNC=15209|UniProtKB=Q8NGK2 Q8NGK2 OR52B4 PTHR26450:SF89 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52B4 transmembrane signal receptor#PC00197 HUMAN|HGNC=31399|UniProtKB=Q9H1V8 Q9H1V8 SLC6A17 PTHR11616:SF102 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER SLC6A17 leucine transport#GO:0015820;neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;amino acid transport#GO:0006865;organic acid transport#GO:0015849;alanine transport#GO:0032328;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;branched-chain amino acid transport#GO:0015803;nitrogen compound transport#GO:0071705;carboxylic acid transport#GO:0046942;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;organic substance transport#GO:0071702;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;anion transport#GO:0006820;sodium ion transmembrane transport#GO:0035725 presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>amine translocator#P00068 HUMAN|HGNC=10387|UniProtKB=P62263 P62263 RPS14 PTHR11759:SF58 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 40S RIBOSOMAL PROTEIN S14 structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;rRNA binding#GO:0019843 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular component assembly#GO:0022607;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;translational elongation#GO:0006414;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|Gene=RP1BL_HUMAN|UniProtKB=A6NIZ1 A6NIZ1 - PTHR24070:SF393 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP-1B-RELATED GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ion binding#GO:0043167 cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;Ras protein signal transduction#GO:0007265;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulated exocytosis#GO:0045055;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of secretion#GO:0051046;synaptic signaling#GO:0099536;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;neurotransmitter secretion#GO:0007269;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;negative regulation of transport#GO:0051051;response to organonitrogen compound#GO:0010243;regulation of cellular localization#GO:0060341;exocytic process#GO:0140029;response to nitrogen compound#GO:1901698;small GTPase mediated signal transduction#GO:0007264;cellular component organization or biogenesis#GO:0071840;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;cellular response to organonitrogen compound#GO:0071417;modulation of chemical synaptic transmission#GO:0050804;regulation of neurotransmitter levels#GO:0001505;regulation of trans-synaptic signaling#GO:0099177;export from cell#GO:0140352;vesicle fusion#GO:0006906;signal transduction#GO:0007165;response to organic cyclic compound#GO:0014070;negative regulation of biological process#GO:0048519;regulation of signaling#GO:0023051;transport#GO:0006810;cellular response to nitrogen compound#GO:1901699;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;regulation of transport#GO:0051049;neurotransmitter transport#GO:0006836;cellular response to organic cyclic compound#GO:0071407;signal release#GO:0023061;vesicle organization#GO:0016050;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;synaptic vesicle exocytosis#GO:0016079;vesicle fusion to plasma membrane#GO:0099500;secretion by cell#GO:0032940;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;response to chemical#GO:0042221;organelle organization#GO:0006996;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#P06803;Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#G06881;Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Gonadotropin-releasing hormone receptor pathway#P06664>Rap1b#G06668;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 HUMAN|HGNC=20122|UniProtKB=Q8NDG6 Q8NDG6 TDRD9 PTHR18934:SF113 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE TDRD9 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 biological regulation#GO:0065007;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;transposition#GO:0032196 RNA helicase#PC00032 HUMAN|HGNC=35126|UniProtKB=Q7RTU4 Q7RTU4 BHLHA9 PTHR23349:SF10 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 9 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=6809|UniProtKB=O15479 O15479 MAGEB2 PTHR11736:SF152 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN B2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=30400|UniProtKB=Q9NS98 Q9NS98 SEMA3G PTHR11036:SF20 SEMAPHORIN SEMAPHORIN-3G receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cellular component movement#GO:0051272;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;neural crest cell differentiation#GO:0014033;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;negative regulation of cellular component movement#GO:0051271;axonogenesis#GO:0007409;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;neuron projection extension#GO:1990138;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;positive regulation of locomotion#GO:0040017;localization of cell#GO:0051674;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;negative regulation of neuron differentiation#GO:0045665;regulation of neuron differentiation#GO:0045664;mesenchymal cell differentiation#GO:0048762;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of axonogenesis#GO:0050770;mesenchyme development#GO:0060485;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;locomotion#GO:0040011;taxis#GO:0042330;regulation of cell morphogenesis involved in differentiation#GO:0010769;neurogenesis#GO:0022008;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;regulation of anatomical structure morphogenesis#GO:0022603;neural crest cell development#GO:0014032;animal organ development#GO:0048513;developmental process#GO:0032502;growth#GO:0040007;cell projection morphogenesis#GO:0048858;regulation of growth#GO:0040008;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;axon guidance#GO:0007411;axon extension#GO:0048675;regulation of chemotaxis#GO:0050920;positive regulation of cell motility#GO:2000147;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;chemotaxis#GO:0006935;regulation of anatomical structure size#GO:0090066;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;regulation of response to external stimulus#GO:0032101;developmental growth involved in morphogenesis#GO:0060560;developmental growth#GO:0048589;negative regulation of response to stimulus#GO:0048585;regulation of cell development#GO:0060284;regulation of cell motility#GO:2000145;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cell growth#GO:0016049;tissue development#GO:0009888;regulation of cellular component size#GO:0032535;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;positive regulation of cell migration#GO:0030335;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of response to external stimulus#GO:0032102;stem cell differentiation#GO:0048863;generation of neurons#GO:0048699;cell migration#GO:0016477 intrinsic component of membrane#GO:0031224;extracellular region#GO:0005576;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=27475|UniProtKB=Q86XJ1 Q86XJ1 GAS2L3 PTHR46756:SF7 TRANSGELIN GAS2-LIKE PROTEIN 3 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;tubulin binding#GO:0015631;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;protein binding#GO:0005515;microtubule binding#GO:0008017;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 HUMAN|HGNC=56|UniProtKB=O15440 O15440 ABCC5 PTHR24223:SF196 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 5 pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;ATPase activity#GO:0016887 localization#GO:0051179;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=25906|UniProtKB=Q8NCF5 Q8NCF5 NFATC2IP PTHR47187:SF1 NFATC2-INTERACTING PROTEIN NFATC2-INTERACTING PROTEIN positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 HUMAN|HGNC=11982|UniProtKB=O60784 O60784 TOM1 PTHR13856:SF32 VHS DOMAIN CONTAINING PROTEIN FAMILY TARGET OF MYB PROTEIN 1 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=5767|UniProtKB=A0A075B7D4 A0A075B7D4 IGKV1OR2-108 PTHR23267:SF376 IMMUNOGLOBULIN LIGHT CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=25953|UniProtKB=Q6N043 Q6N043 ZNF280D PTHR24388:SF34 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 280D cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=30672|UniProtKB=Q8N3V7 Q8N3V7 SYNPO PTHR24217:SF13 PUTATIVE-RELATED SYNAPTOPODIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;positive regulation of cytoskeleton organization#GO:0051495;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;actin cytoskeleton organization#GO:0030036;positive regulation of biological process#GO:0048518 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;Z disc#GO:0030018;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;contractile fiber#GO:0043292;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;sarcomere#GO:0030017;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;myofibril#GO:0030016;I band#GO:0031674 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=19579|UniProtKB=A6NMU1 A6NMU1 OR52A4P PTHR26450:SF189 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 52A4 transmembrane signal receptor#PC00197 HUMAN|HGNC=2512|UniProtKB=Q9UBT7 Q9UBT7 CTNNAL1 PTHR46342:SF1 ALPHA-CATULIN ALPHA-CATULIN Wnt signaling pathway#P00057>alpha-catenin#P01471 HUMAN|HGNC=16795|UniProtKB=Q6H3X3 Q6H3X3 RAET1G PTHR16675:SF232 MHC CLASS I-RELATED UL-16 BINDING PROTEIN 5 response to stimulus#GO:0050896;immune system process#GO:0002376;immune response#GO:0006955 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;extracellular region#GO:0005576;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 major histocompatibility complex protein#PC00149 HUMAN|HGNC=10296|UniProtKB=Q9UNE2 Q9UNE2 RPH3AL PTHR45729:SF4 RABPHILIN, ISOFORM A RAB EFFECTOR NOC2 HUMAN|HGNC=24881|UniProtKB=Q0VAM2 Q0VAM2 RASGEF1B PTHR23113:SF197 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1B guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=20190|UniProtKB=Q6P0N0 Q6P0N0 MIS18BP1 PTHR16124:SF3 MIS18-BINDING PROTEIN 1 MIS18-BINDING PROTEIN 1 membrane-enclosed lumen#GO:0031974;supramolecular complex#GO:0099080;organelle lumen#GO:0043233;kinetochore#GO:0000776;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;condensed chromosome, centromeric region#GO:0000779;intracellular organelle lumen#GO:0070013;chromosome, centromeric region#GO:0000775;condensed nuclear chromosome, centromeric region#GO:0000780;condensed nuclear chromosome#GO:0000794;cellular anatomical entity#GO:0110165;organelle#GO:0043226;condensed nuclear chromosome kinetochore#GO:0000778;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;chromosomal region#GO:0098687 HUMAN|HGNC=14374|UniProtKB=Q9C000 Q9C000 NLRP1 PTHR46985:SF3 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1 positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of programmed cell death#GO:0043068;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of hydrolase activity#GO:0051336;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;positive regulation of peptidase activity#GO:0010952;positive regulation of biological process#GO:0048518;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;positive regulation of cellular protein metabolic process#GO:0032270;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;positive regulation of cell death#GO:0010942;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 inflammasome complex#GO:0061702;cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=29451|UniProtKB=Q9BYJ0 Q9BYJ0 FGFBP2 PTHR15258:SF1 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 2 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 HUMAN|HGNC=15877|UniProtKB=Q9BV94 Q9BV94 EDEM2 PTHR45679:SF6 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 HUMAN|HGNC=30257|UniProtKB=Q9BRQ0 Q9BRQ0 PYGO2 PTHR23194:SF7 PYGOPUS PYGOPUS HOMOLOG 2 Wnt signaling pathway#P00057>Pygo#P01464 HUMAN|HGNC=9354|UniProtKB=P30048 P30048 PRDX3 PTHR42801:SF4 THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;homeostatic process#GO:0042592;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular homeostasis#GO:0019725;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;regulation of biological quality#GO:0065008;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cellular response to oxidative stress#GO:0034599;biological regulation#GO:0065007;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 peroxidase#PC00180 HUMAN|HGNC=13735|UniProtKB=P49795 P49795 RGS19 PTHR10845:SF145 REGULATOR OF G PROTEIN SIGNALING REGULATOR OF G-PROTEIN SIGNALING 19 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 HUMAN|HGNC=24156|UniProtKB=Q96BD5 Q96BD5 PHF21A PTHR24102:SF6 PHD FINGER PROTEIN PHD FINGER PROTEIN 21A chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=27603|UniProtKB=O75290 O75290 ZNF780A PTHR24377:SF287 IP01015P-RELATED ZINC FINGER PROTEIN 780A cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=22146|UniProtKB=Q2M3M2 Q2M3M2 SLC5A9 PTHR11819:SF96 SOLUTE CARRIER FAMILY 5 SODIUM/GLUCOSE COTRANSPORTER 4 inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;sugar transmembrane transporter activity#GO:0051119;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;solute:cation symporter activity#GO:0015294;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=10429|UniProtKB=P62753 P62753 RPS6 PTHR11502:SF33 40S RIBOSOMAL PROTEIN S6 40S RIBOSOMAL PROTEIN S6 ribosomal protein#PC00202 CCKR signaling map#P06959>RPS6#P07143 HUMAN|HGNC=14006|UniProtKB=Q9H1D0 Q9H1D0 TRPV6 PTHR10582:SF25 TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 6 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;divalent metal ion transport#GO:0070838;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=29639|UniProtKB=Q9HAY2 Q9HAY2 MAGEF1 PTHR11736:SF61 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN F1 scaffold/adaptor protein#PC00226 HUMAN|HGNC=4594|UniProtKB=Q14416 Q14416 GRM2 PTHR24060:SF147 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 2 adenylate cyclase activity#GO:0004016;amino acid binding#GO:0016597;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;carboxylic acid binding#GO:0031406;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;glutamate binding#GO:0016595 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Ionotropic glutamate receptor pathway#P00037>mGluR 2/3#P01014;Metabotropic glutamate receptor group II pathway#P00040>mGluR2/3#P01048;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=7146|UniProtKB=Q7Z4N2 Q7Z4N2 TRPM1 PTHR13800:SF13 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;cation transport#GO:0006812;cellular homeostasis#GO:0019725;cation transmembrane transport#GO:0098655;calcium ion transport#GO:0006816;divalent metal ion transport#GO:0070838;cellular calcium ion homeostasis#GO:0006874;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;calcium ion transport into cytosol#GO:0060402;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=26927|UniProtKB=Q96CU9 Q96CU9 FOXRED1 PTHR13847:SF44 SARCOSINE DEHYDROGENASE-RELATED FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;protein-containing complex assembly#GO:0065003;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=4061|UniProtKB=O43826 O43826 SLC37A4 PTHR43826:SF3 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 primary active transporter#PC00068 HUMAN|HGNC=15472|UniProtKB=O94788 O94788 ALDH1A2 PTHR11699:SF102 ALDEHYDE DEHYDROGENASE-RELATED RETINAL DEHYDROGENASE 2 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=5636|UniProtKB=A0A075B7B8 A0A075B7B8 IGHV3OR16-12 PTHR23266:SF204 IMMUNOGLOBULIN HEAVY CHAIN IGV DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=21326|UniProtKB=P84550 P84550 SKOR1 PTHR10005:SF8 SKI ONCOGENE-RELATED SKI FAMILY TRANSCRIPTIONAL COREPRESSOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;response to growth factor#GO:0070848;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=14434|UniProtKB=Q96Q40 Q96Q40 CDK15 PTHR24056:SF159 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 15 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;protein modification process#GO:0036211;biosynthetic process#GO:0009058;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=534|UniProtKB=Q9UJ72 Q9UJ72 ANXA10 PTHR10502:SF100 ANNEXIN ANNEXIN A10 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 calcium-binding protein#PC00060 HUMAN|HGNC=14469|UniProtKB=Q7LBE3 Q7LBE3 SLC26A9 PTHR11814:SF17 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 9 inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;anion:anion antiporter activity#GO:0015301;organic acid transmembrane transporter activity#GO:0005342;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;organic anion transmembrane transporter activity#GO:0008514;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;inorganic anion transmembrane transporter activity#GO:0015103;active ion transmembrane transporter activity#GO:0022853 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=3660|UniProtKB=Q9UHY8 Q9UHY8 FEZ2 PTHR12394:SF11 ZYGIN FASCICULATION AND ELONGATION PROTEIN ZETA-2 cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;axon#GO:0030424 HUMAN|HGNC=29983|UniProtKB=Q9HA38 Q9HA38 ZMAT3 PTHR46786:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 3 ZINC FINGER MATRIN-TYPE PROTEIN 3 p53 pathway#P00059>PAG608#G04690 HUMAN|Gene=CNK3/IPCEF1|UniProtKB=G9CGD6 G9CGD6 CNK3/IPCEF1 PTHR12844:SF45 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CNK3/IPCEF1 FUSION PROTEIN-RELATED HUMAN|HGNC=26939|UniProtKB=Q9P013 Q9P013 CWC15 PTHR12718:SF2 CELL CYCLE CONTROL PROTEIN CWF15 SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA cis splicing, via spliceosome#GO:0045292;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;U5 snRNP#GO:0005682;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;Prp19 complex#GO:0000974;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=29157|UniProtKB=Q9Y2G8 Q9Y2G8 DNAJC16 PTHR44303:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 chaperone#PC00072 HUMAN|HGNC=17557|UniProtKB=Q9UIC8 Q9UIC8 LCMT1 PTHR13600:SF21 LEUCINE CARBOXYL METHYLTRANSFERASE LEUCINE CARBOXYL METHYLTRANSFERASE 1 methyltransferase#PC00155 HUMAN|HGNC=550|UniProtKB=Q16853 Q16853 AOC3 PTHR10638:SF85 COPPER AMINE OXIDASE MEMBRANE PRIMARY AMINE OXIDASE cation binding#GO:0043169;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;copper ion binding#GO:0005507;metal ion binding#GO:0046872;ion binding#GO:0043167;oxidoreductase activity#GO:0016491 negative regulation of biological process#GO:0048519;organonitrogen compound metabolic process#GO:1901564;negative regulation of metabolic process#GO:0009892;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to chemical#GO:0042221;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;oxidation-reduction process#GO:0055114;biological regulation#GO:0065007;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;negative regulation of molecular function#GO:0044092 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886 oxidase#PC00175 Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103 HUMAN|HGNC=20203|UniProtKB=Q8IVI9 Q8IVI9 NOSTRIN PTHR14167:SF31 SH3 DOMAIN-CONTAINING NOSTRIN HUMAN|HGNC=14639|UniProtKB=Q96J66 Q96J66 ABCC11 PTHR24223:SF168 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 11 catalytic activity#GO:0003824;organophosphate ester transmembrane transporter activity#GO:0015605;ion transmembrane transporter activity#GO:0015075;organic anion transmembrane transporter activity#GO:0008514;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;purine nucleotide transmembrane transporter activity#GO:0015216;anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside-triphosphatase activity#GO:0017111;nucleotide transmembrane transporter activity#GO:0015215;ATPase activity#GO:0016887 localization#GO:0051179;organic substance transport#GO:0071702;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810;cellular process#GO:0009987 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=24686|UniProtKB=Q8WUP2 Q8WUP2 FBLIM1 PTHR24207:SF1 ZYX102 PROTEIN FILAMIN-BINDING LIM PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;actin filament#GO:0005884;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;stress fiber#GO:0001725;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cytoskeleton#GO:0005856 kinase modulator#PC00140 HUMAN|HGNC=29433|UniProtKB=Q5QGS0 Q5QGS0 NEXMIF PTHR46946:SF1 NEURITE EXTENSION AND MIGRATION FACTOR NEURITE EXTENSION AND MIGRATION FACTOR negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;regulation of locomotion#GO:0040012;regulation of cell-cell adhesion#GO:0022407;negative regulation of cell-cell adhesion#GO:0022408;cell adhesion mediated by integrin#GO:0033627;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of localization#GO:0032879;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of cell differentiation#GO:0045595;regulation of biological process#GO:0050789;system development#GO:0048731;negative regulation of multicellular organismal process#GO:0051241;cell differentiation#GO:0030154;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;negative regulation of cell motility#GO:2000146;regulation of cell adhesion#GO:0030155;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;negative regulation of locomotion#GO:0040013;regulation of multicellular organismal process#GO:0051239;regulation of cell motility#GO:2000145;regulation of cell development#GO:0060284;multicellular organism development#GO:0007275;localization of cell#GO:0051674;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;negative regulation of cell adhesion#GO:0007162;localization#GO:0051179;cell development#GO:0048468;regulation of neurogenesis#GO:0050767;cell-matrix adhesion#GO:0007160;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;neuron migration#GO:0001764;regulation of nervous system development#GO:0051960;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell migration#GO:0016477;locomotion#GO:0040011 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12556|UniProtKB=Q96T88 Q96T88 UHRF1 PTHR14140:SF2 E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED E3 UBIQUITIN-PROTEIN LIGASE UHRF1 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;nucleobase-containing compound metabolic process#GO:0006139;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;histone ubiquitination#GO:0016574;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein monoubiquitination#GO:0006513;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;covalent chromatin modification#GO:0016569;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;nuclear heterochromatin#GO:0005720;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=17866|UniProtKB=Q96D42 Q96D42 HAVCR1 PTHR47009:SF1 HEPATITIS A VIRUS CELLULAR RECEPTOR 1 HOMOLOG HEPATITIS A VIRUS CELLULAR RECEPTOR 1 lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylserine binding#GO:0001786 membrane organization#GO:0061024;phagocytosis#GO:0006909;transport#GO:0006810;endocytosis#GO:0006897;positive regulation of immune system process#GO:0002684;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of leukocyte activation#GO:0002696;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cell activation#GO:0001775;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;positive regulation of cell activation#GO:0050867;leukocyte activation#GO:0045321;positive regulation of biological process#GO:0048518 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|HGNC=11432|UniProtKB=P56962 P56962 STX17 PTHR19957:SF139 SYNTAXIN SYNTAXIN-17 molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 SNARE protein#PC00034 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 HUMAN|HGNC=7034|UniProtKB=P55082 P55082 MFAP3 PTHR14340:SF4 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=26340|UniProtKB=Q32M84 Q32M84 BTBD16 PTHR46843:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 16 BTB/POZ DOMAIN-CONTAINING PROTEIN 16 HUMAN|HGNC=2637|UniProtKB=P08684 P08684 CYP3A4 PTHR24302:SF38 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A4 steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 lipid metabolic process#GO:0006629;steroid metabolic process#GO:0008202;organic cyclic compound metabolic process#GO:1901360;oxidative demethylation#GO:0070989;oxidation-reduction process#GO:0055114;demethylation#GO:0070988;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177 HUMAN|HGNC=2978|UniProtKB=Q9Y6K1 Q9Y6K1 DNMT3A PTHR23068:SF10 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3A DNA methyltransferase#PC00013 HUMAN|HGNC=10882|UniProtKB=P81133 P81133 SIM1 PTHR23043:SF22 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA SINGLE-MINDED HOMOLOG 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=10440|UniProtKB=P62081 P62081 RPS7 PTHR11278:SF5 40S RIBOSOMAL PROTEIN S7 40S RIBOSOMAL PROTEIN S7 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;preribosome#GO:0030684;small ribosomal subunit#GO:0015935;ribosome#GO:0005840;90S preribosome#GO:0030686 ribosomal protein#PC00202 HUMAN|HGNC=16393|UniProtKB=Q9BXL7 Q9BXL7 CARD11 PTHR14559:SF4 CASPASE RECRUITMENT DOMAIN FAMILY CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 11 protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=8565|UniProtKB=Q86U42 Q86U42 PABPN1 PTHR23236:SF16 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H POLYADENYLATE-BINDING PROTEIN 2 translation initiation factor#PC00224 HUMAN|HGNC=34549|UniProtKB=A6NKC9 A6NKC9 SH2D7 PTHR14388:SF6 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 7 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 defense/immunity protein#PC00090 HUMAN|HGNC=16142|UniProtKB=Q9H3Y8 Q9H3Y8 PPDPF PTHR14572:SF0 PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR HUMAN|HGNC=24935|UniProtKB=Q8TD90 Q8TD90 MAGEE2 PTHR11736:SF7 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN MELANOMA-ASSOCIATED ANTIGEN E2 scaffold/adaptor protein#PC00226 HUMAN|HGNC=1409|UniProtKB=Q9UF02 Q9UF02 CACNG5 PTHR12107:SF4 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-5 SUBUNIT calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;cation channel activity#GO:0005261;voltage-gated ion channel activity#GO:0005244;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;molecular function regulator#GO:0098772;channel regulator activity#GO:0016247;inorganic cation transmembrane transporter activity#GO:0022890 cellular localization#GO:0051641;membrane organization#GO:0061024;system process#GO:0003008;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;lysosomal transport#GO:0007041;establishment of protein localization#GO:0045184;regulation of ion transmembrane transporter activity#GO:0032412;regulation of biological process#GO:0050789;membrane invagination#GO:0010324;anterograde trans-synaptic signaling#GO:0098916;establishment of localization#GO:0051234;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;synaptic signaling#GO:0099536;regulation of transmembrane transporter activity#GO:0022898;positive regulation of signaling#GO:0023056;regulation of transporter activity#GO:0032409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;establishment of protein localization to vacuole#GO:0072666;regulation of transmembrane transport#GO:0034762;regulation of cation channel activity#GO:2001257;protein localization to synapse#GO:0035418;macromolecule metabolic process#GO:0043170;endocytosis#GO:0006897;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;peptide transport#GO:0015833;ion transmembrane transport#GO:0034220;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of ion transmembrane transport#GO:0034765;protein localization to lysosome#GO:0061462;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein localization to cell junction#GO:1902414;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;protein transport#GO:0015031;regulation of trans-synaptic signaling#GO:0099177;regulation of ion transport#GO:0043269;multicellular organismal process#GO:0032501;protein-containing complex localization#GO:0031503;receptor localization to synapse#GO:0097120;signal transduction#GO:0007165;regulation of neurotransmitter receptor activity#GO:0099601;receptor internalization#GO:0031623;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;action potential#GO:0001508;cation transport#GO:0006812;ionotropic glutamate receptor signaling pathway#GO:0035235;cation transmembrane transport#GO:0098655;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;vesicle organization#GO:0016050;protein localization to organelle#GO:0033365;receptor-mediated endocytosis#GO:0006898;signaling#GO:0023052;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of cation transmembrane transport#GO:1904062;transmembrane transport#GO:0055085;vacuolar transport#GO:0007034;protein localization to membrane#GO:0072657;regulation of membrane potential#GO:0042391;protein localization to vacuole#GO:0072665;ion transport#GO:0006811;establishment of protein localization to organelle#GO:0072594;regulation of AMPA receptor activity#GO:2000311;nervous system process#GO:0050877;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;protein localization to cell periphery#GO:1990778;localization#GO:0051179;response to stimulus#GO:0050896;regulation of signaling receptor activity#GO:0010469;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of synaptic transmission#GO:0050806;synaptic transmission, glutamatergic#GO:0035249 membrane protein complex#GO:0098796;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;ion channel complex#GO:0034702;cell junction#GO:0030054;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;membrane#GO:0016020;organelle#GO:0043226;integral component of membrane#GO:0016021;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;asymmetric synapse#GO:0032279;receptor complex#GO:0043235;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;transmembrane transporter complex#GO:1902495;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;ionotropic glutamate receptor complex#GO:0008328;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>stargazin#P00998 HUMAN|HGNC=3114|UniProtKB=Q14209 Q14209 E2F2 PTHR12081:SF50 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|Ensembl=ENSG00000284434|UniProtKB=A0A1W2PR80 A0A1W2PR80 ENSG00000284434 PTHR15566:SF5 POM121-LIKE POM121-LIKE PROTEIN 1-LIKE-RELATED HUMAN|HGNC=18859|UniProtKB=Q9NRA0 Q9NRA0 SPHK2 PTHR12358:SF40 SPHINGOSINE KINASE SPHINGOSINE KINASE 2 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;alcohol biosynthetic process#GO:0046165;organic hydroxy compound biosynthetic process#GO:1901617;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;apoptotic process#GO:0006915;cell death#GO:0008219;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;membrane lipid biosynthetic process#GO:0046467;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;membrane lipid metabolic process#GO:0006643;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;positive regulation of cell death#GO:0010942;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229 kinase#PC00137 Angiogenesis#P00005>SPK#P00229;VEGF signaling pathway#P00056>SPK#P01404 HUMAN|HGNC=8888|UniProtKB=P18669 P18669 PGAM1 PTHR11931:SF15 PHOSPHOGLYCERATE MUTASE PHOSPHOGLYCERATE MUTASE 1 mutase#PC00160 Glycolysis#P00024>Phosphoglyceromutase#P00680 HUMAN|HGNC=10700|UniProtKB=O75396 O75396 SEC22B PTHR45837:SF3 VESICLE-TRAFFICKING PROTEIN SEC22B VESICLE-TRAFFICKING PROTEIN SEC22B molecular adaptor activity#GO:0060090;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular localization#GO:0051641;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;intracellular#GO:0005622;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane protein complex#GO:0098796;ER to Golgi transport vesicle membrane#GO:0012507;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;whole membrane#GO:0098805;cytoplasm#GO:0005737;Golgi-associated vesicle membrane#GO:0030660;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 HUMAN|HGNC=1174|UniProtKB=Q96F05 Q96F05 C11orf24 PTHR16021:SF9 MANSC DOMAIN CONTAINING PROTEIN 1 CHROMOSOME 11 OPEN READING FRAME 24 HUMAN|HGNC=25117|UniProtKB=Q0D2K3 Q0D2K3 RIPPLY1 PTHR16770:SF5 FAMILY NOT NAMED PROTEIN RIPPLY1 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=14718|UniProtKB=Q8NGQ6 Q8NGQ6 OR9I1 PTHR48018:SF58 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 9I1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=18871|UniProtKB=Q8IVH4 Q8IVH4 MMAA PTHR23408:SF3 METHYLMALONYL-COA MUTASE METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL mutase#PC00160 HUMAN|HGNC=33469|UniProtKB=Q30KR1 Q30KR1 DEFB109B PTHR20515:SF3 BETA-DEFENSIN BETA-DEFENSIN 109B-RELATED receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;interspecies interaction between organisms#GO:0044419;localization of cell#GO:0051674;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;localization#GO:0051179;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;response to chemical#GO:0042221;defense response to other organism#GO:0098542;response to other organism#GO:0051707;movement of cell or subcellular component#GO:0006928;defense response#GO:0006952;cell migration#GO:0016477;locomotion#GO:0040011;chemotaxis#GO:0006935;taxis#GO:0042330 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 antimicrobial response protein#PC00051 HUMAN|HGNC=24857|UniProtKB=Q9NRH1 Q9NRH1 YAE1 PTHR18829:SF0 PROTEIN YAE1 HOMOLOG PROTEIN YAE1 HOMOLOG HUMAN|HGNC=15606|UniProtKB=Q9UHA4 Q9UHA4 LAMTOR3 PTHR13378:SF1 REGULATOR COMPLEX PROTEIN LAMTOR3 RAGULATOR COMPLEX PROTEIN LAMTOR3 signal transduction#GO:0007165;positive regulation of signal transduction#GO:0009967;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to nitrogen compound#GO:1901699;regulation of biological process#GO:0050789;positive regulation of response to stimulus#GO:0048584;cellular response to oxygen-containing compound#GO:1901701;response to endogenous stimulus#GO:0009719;positive regulation of TOR signaling#GO:0032008;regulation of signal transduction#GO:0009966;positive regulation of intracellular signal transduction#GO:1902533;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;signaling#GO:0023052;TOR signaling#GO:0031929;response to organic substance#GO:0010033;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to organonitrogen compound#GO:0071417;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;membrane raft#GO:0045121;membrane microdomain#GO:0098857;membrane region#GO:0098589;late endosome#GO:0005770;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=701|UniProtKB=O00327 O00327 ARNTL PTHR23042:SF52 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;rhythmic process#GO:0048511;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 receptor complex#GO:0043235;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 Circadian clock system#P00015>BMAL1#P00506;Circadian clock system#P00015>bmal1#G01500;Circadian clock system#P00015>bmal1#G01504 HUMAN|HGNC=3032|UniProtKB=Q13474 Q13474 DRP2 PTHR12268:SF16 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN-RELATED PROTEIN 2 synaptic signaling#GO:0099536;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052;cell-cell signaling#GO:0007267 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=11837|UniProtKB=Q04724 Q04724 TLE1 PTHR10814:SF29 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSDUCIN-LIKE ENHANCER PROTEIN 1 repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;protein binding#GO:0005515;molecular function regulator#GO:0098772;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cell-cell signaling by wnt#GO:0198738;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell-cell signaling#GO:0007267;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;canonical Wnt signaling pathway#GO:0060070;Wnt signaling pathway#GO:0016055 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 HUMAN|HGNC=18941|UniProtKB=Q3LI70 Q3LI70 KRTAP19-6 PTHR38140:SF8 KERATIN-ASSOCIATED PROTEIN 19-3-RELATED KERATIN-ASSOCIATED PROTEIN 19-6 HUMAN|HGNC=7134|UniProtKB=Q03111 Q03111 MLLT1 PTHR23195:SF14 YEATS DOMAIN PROTEIN ENL general transcription factor#PC00259 HUMAN|HGNC=29003|UniProtKB=O15014 O15014 ZNF609 PTHR21564:SF2 BRAKELESS PROTEIN ZINC FINGER PROTEIN 609 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=8811|UniProtKB=Q15120 Q15120 PDK3 PTHR11947:SF21 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE ISOZYME 3, MITOCHONDRIAL transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;negative regulation of metabolic process#GO:0009892;regulation of catalytic activity#GO:0050790;chemical homeostasis#GO:0048878;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=18808|UniProtKB=Q9Y6E2 Q9Y6E2 BZW2 PTHR14208:SF7 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN 2 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 basic leucine zipper transcription factor#PC00056 HUMAN|HGNC=3300|UniProtKB=P63241 P63241 EIF5A PTHR11673:SF34 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-1 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159 positive regulation of gene expression#GO:0010628;positive regulation of nitrogen compound metabolic process#GO:0051173;posttranscriptional regulation of gene expression#GO:0010608;positive regulation of cellular amide metabolic process#GO:0034250;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;positive regulation of translation#GO:0045727;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;peptide biosynthetic process#GO:0043043;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;positive regulation of cellular protein metabolic process#GO:0032270;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603;regulation of cellular metabolic process#GO:0031323 translation initiation factor#PC00224 HUMAN|HGNC=20718|UniProtKB=Q8TE49 Q8TE49 OTUD7A PTHR13367:SF9 UBIQUITIN THIOESTERASE OTU DOMAIN-CONTAINING PROTEIN 7A thiol-dependent ubiquitin-specific protease activity#GO:0004843;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein K63-linked deubiquitination#GO:0070536;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein K48-linked deubiquitination#GO:0071108;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;protein modification by small protein removal#GO:0070646;protein deubiquitination#GO:0016579;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=16227|UniProtKB=Q9NUD7 Q9NUD7 C20orf96 PTHR28574:SF1 RIKEN CDNA 6820408C15 RIKEN CDNA 6820408C15 GENE HUMAN|HGNC=28433|UniProtKB=Q6ZMD2 Q6ZMD2 SPNS3 PTHR23505:SF3 SPINSTER PROTEIN SPINSTER HOMOLOG 3 transporter#PC00227 HUMAN|HGNC=12806|UniProtKB=P55808 P55808 XG PTHR15076:SF4 CD99/MIC2 PROTEIN RELATED GLYCOPROTEIN XG regulation of locomotion#GO:0040012;biological adhesion#GO:0022610;regulation of localization#GO:0032879;homotypic cell-cell adhesion#GO:0034109;positive regulation of cellular component movement#GO:0051272;positive regulation of leukocyte migration#GO:0002687;regulation of biological process#GO:0050789;leukocyte migration#GO:0050900;granulocyte migration#GO:0097530;regulation of cell migration#GO:0030334;regulation of leukocyte migration#GO:0002685;positive regulation of cell motility#GO:2000147;myeloid leukocyte migration#GO:0097529;regulation of immune system process#GO:0002682;positive regulation of biological process#GO:0048518;regulation of cellular component movement#GO:0051270;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017;neutrophil migration#GO:1990266;localization of cell#GO:0051674;cell-cell adhesion#GO:0098609;positive regulation of immune system process#GO:0002684;cell adhesion#GO:0007155;cell motility#GO:0048870;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;localization#GO:0051179;immune system process#GO:0002376;positive regulation of cell migration#GO:0030335;lymphocyte migration#GO:0072676;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;cell migration#GO:0016477;locomotion#GO:0040011 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 HUMAN|HGNC=25660|UniProtKB=Q7Z4L5 Q7Z4L5 TTC21B PTHR14699:SF1 STI2 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 21B microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular localization#GO:0051641;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;intraciliary retrograde transport#GO:0035721;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein-containing complex localization#GO:0031503 protein-containing complex#GO:0032991;intraciliary transport particle#GO:0030990 HUMAN|HGNC=20038|UniProtKB=Q9Y2R4 Q9Y2R4 DDX52 PTHR24031:SF594 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX52-RELATED HUMAN|Ensembl=ENSG00000250719|UniProtKB=A0A087WWA1 A0A087WWA1 P3R3URF PTHR10155:SF27 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PIK3R3 UPSTREAM OPEN READING FRAME PROTEIN transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;phosphorylation#GO:0016310;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;phosphatidylinositol phosphorylation#GO:0046854;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165;membrane#GO:0016020;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase modulator#PC00140 HUMAN|HGNC=28188|UniProtKB=Q9BRQ4 Q9BRQ4 CFAP300 PTHR31078:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300 structural protein#PC00211 HUMAN|HGNC=10625|UniProtKB=Q9Y258 Q9Y258 CCL26 PTHR12015:SF73 SMALL INDUCIBLE CYTOKINE A C-C MOTIF CHEMOKINE 26 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function regulator#GO:0098772;G protein-coupled receptor binding#GO:0001664;chemokine receptor binding#GO:0042379;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 response to external biotic stimulus#GO:0043207;regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;response to cytokine#GO:0034097;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;regulation of phosphorus metabolic process#GO:0051174;granulocyte migration#GO:0097530;leukocyte migration#GO:0050900;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;innate immune response#GO:0045087;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;leukocyte chemotaxis#GO:0030595;positive regulation of signaling#GO:0023056;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular response to organic substance#GO:0071310;regulation of GTPase activity#GO:0043087;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;positive regulation of phosphorus metabolic process#GO:0010562;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;response to tumor necrosis factor#GO:0034612;positive regulation of phosphate metabolic process#GO:0045937;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of cell communication#GO:0010647;movement of cell or subcellular component#GO:0006928;response to interleukin-1#GO:0070555;G protein-coupled receptor signaling pathway#GO:0007186;positive regulation of ERK1 and ERK2 cascade#GO:0070374;cellular response to tumor necrosis factor#GO:0071356;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;taxis#GO:0042330;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;inflammatory response#GO:0006954;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of metabolic process#GO:0009893;granulocyte chemotaxis#GO:0071621;myeloid leukocyte migration#GO:0097529;phosphorylation#GO:0016310;positive regulation of intracellular signal transduction#GO:1902533;cytokine-mediated signaling pathway#GO:0019221;protein metabolic process#GO:0019538;signaling#GO:0023052;chemotaxis#GO:0006935;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;ERK1 and ERK2 cascade#GO:0070371;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;immune response#GO:0006955;neutrophil migration#GO:1990266;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell motility#GO:0048870;cellular process#GO:0009987;cell chemotaxis#GO:0060326;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein metabolic process#GO:0051247;lymphocyte migration#GO:0072676;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;cellular response to cytokine stimulus#GO:0071345;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 cytokine#PC00083 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CHK#P00856 HUMAN|HGNC=21228|UniProtKB=Q96Q07 Q96Q07 BTBD9 PTHR46306:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 9 BTB/POZ DOMAIN-CONTAINING PROTEIN 9 HUMAN|HGNC=8669|UniProtKB=Q9Y5H8 Q9Y5H8 PCDHA3 PTHR24028:SF133 CADHERIN-87A PROTOCADHERIN ALPHA-3 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=6122|UniProtKB=Q92985 Q92985 IRF7 PTHR11949:SF2 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 7 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 Toll receptor signaling pathway#P00054>IRF3#P01374 HUMAN|HGNC=29424|UniProtKB=Q8TF21 Q8TF21 ANKRD24 PTHR24173:SF16 FAMILY NOT NAMED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 24 HUMAN|HGNC=28192|UniProtKB=Q96SK3 Q96SK3 ZNF607 PTHR24377:SF819 IP01015P-RELATED ZINC FINGER PROTEIN 607 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=29859|UniProtKB=Q9P2A4 Q9P2A4 ABI3 PTHR10460:SF7 ABL INTERACTOR FAMILY MEMBER ABI GENE FAMILY MEMBER 3 protein binding#GO:0005515;binding#GO:0005488 cell leading edge#GO:0031252;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28802|UniProtKB=Q32NC0 Q32NC0 C18orf21 PTHR31402:SF2 UPF0711 PROTEIN C18ORF21 UPF0711 PROTEIN C18ORF21 HUMAN|HGNC=24259|UniProtKB=Q9Y3C4 Q9Y3C4 TPRKB PTHR15840:SF10 CGI-121 FAMILY MEMBER EKC/KEOPS COMPLEX SUBUNIT TPRKB cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;macromolecule modification#GO:0043412;telomere organization#GO:0032200;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;telomere maintenance#GO:0000723;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;mitotic recombination#GO:0006312;tRNA threonylcarbamoyladenosine metabolic process#GO:0070525;anatomical structure homeostasis#GO:0060249;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;homeostatic process#GO:0042592;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;chromosome organization#GO:0051276;organelle organization#GO:0006996;biological regulation#GO:0065007;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;EKC/KEOPS complex#GO:0000408;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=6316|UniProtKB=Q92945 Q92945 KHSRP PTHR10288:SF101 KH DOMAIN CONTAINING RNA BINDING PROTEIN FAR UPSTREAM ELEMENT-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=1228|UniProtKB=P05155 P05155 SERPING1 PTHR11461:SF159 SERINE PROTEASE INHIBITOR, SERPIN PLASMA PROTEASE C1 INHIBITOR serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=21299|UniProtKB=Q5TZA2 Q5TZA2 CROCC PTHR23159:SF17 CENTROSOMAL PROTEIN 2 ROOTLETIN chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=29290|UniProtKB=Q9P244 Q9P244 LRFN1 PTHR45842:SF7 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1 intrinsic component of postsynaptic membrane#GO:0098936;synapse#GO:0045202;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;integral component of synaptic membrane#GO:0099699;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;synaptic membrane#GO:0097060;integral component of postsynaptic specialization membrane#GO:0099060;integral component of postsynaptic membrane#GO:0099055;asymmetric synapse#GO:0032279;cell surface#GO:0009986;intrinsic component of membrane#GO:0031224;intrinsic component of synaptic membrane#GO:0099240;integral component of postsynaptic density membrane#GO:0099061;postsynaptic density membrane#GO:0098839;integral component of plasma membrane#GO:0005887;postsynaptic specialization membrane#GO:0099634;plasma membrane region#GO:0098590;intrinsic component of postsynaptic specialization membrane#GO:0098948;postsynapse#GO:0098794;intrinsic component of plasma membrane#GO:0031226;plasma membrane#GO:0005886 HUMAN|HGNC=18994|UniProtKB=Q8TDC3 Q8TDC3 BRSK1 PTHR24343:SF130 SERINE/THREONINE KINASE SERINE/THREONINE-PROTEIN KINASE BRSK1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 establishment or maintenance of cell polarity#GO:0007163;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;system development#GO:0048731;establishment of cell polarity#GO:0030010;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular protein metabolic process#GO:0044267;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stimulus#GO:0050896;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=21365|UniProtKB=Q9HD34 Q9HD34 LYRM4 PTHR13166:SF7 PROTEIN C6ORF149 LYR MOTIF-CONTAINING PROTEIN 4 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=1350|UniProtKB=Q8WWH4 Q8WWH4 ASZ1 PTHR24157:SF3 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=33896|UniProtKB=Q6S5H5 Q6S5H5 POTEG PTHR24118:SF94 POTE ANKYRIN DOMAIN POTE ANKYRIN DOMAIN FAMILY MEMBER E-RELATED membrane traffic protein#PC00150 HUMAN|HGNC=33834|UniProtKB=Q6ZN32 Q6ZN32 ETV3L PTHR11849:SF300 ETS ETS TRANSLOCATION VARIANT 3-LIKE PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=21647|UniProtKB=Q9Y2X8 Q9Y2X8 UBE2D4 PTHR24068:SF448 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 D4 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein K48-linked ubiquitination#GO:0070936;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 HUMAN|HGNC=49151|UniProtKB=Q9Y3D8 Q9Y3D8 AK6 PTHR12595:SF19 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylate kinase activity#GO:0004017;kinase activity#GO:0016301;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;nucleobase-containing compound kinase activity#GO:0019205;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=13944|UniProtKB=Q99944 Q99944 EGFL8 PTHR14949:SF27 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 8 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 anatomical structure development#GO:0048856;developmental process#GO:0032502 cell surface#GO:0009986;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 HUMAN|HGNC=9343|UniProtKB=Q92733 Q92733 PRCC PTHR13621:SF2 PROLINE-RICH PROTEIN PRCC PROLINE-RICH PROTEIN PRCC negative regulation of biological process#GO:0048519;mitotic cell cycle checkpoint#GO:0007093;negative regulation of cell cycle#GO:0045786;nuclear division#GO:0000280;cell cycle process#GO:0022402;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;cell cycle checkpoint#GO:0000075;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=19695|UniProtKB=Q14512 Q14512 FGFBP1 PTHR15258:SF2 FGF BINDING PROTEIN-RELATED FIBROBLAST GROWTH FACTOR-BINDING PROTEIN 1 growth factor binding#GO:0019838;protein binding#GO:0005515;binding#GO:0005488 cell communication#GO:0007154;cellular process#GO:0009987;cell-cell signaling#GO:0007267;signaling#GO:0023052 HUMAN|HGNC=14296|UniProtKB=Q8N339 Q8N339 MT1M PTHR23299:SF48 METALLOTHIONEIN METALLOTHIONEIN-1E-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;cellular transition metal ion homeostasis#GO:0046916;inorganic ion homeostasis#GO:0098771;cellular response to stimulus#GO:0051716;cellular cation homeostasis#GO:0030003;response to inorganic substance#GO:0010035;divalent inorganic cation homeostasis#GO:0072507;cellular response to chemical stimulus#GO:0070887;transition metal ion homeostasis#GO:0055076;response to metal ion#GO:0010038;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;cellular process#GO:0009987;response to cadmium ion#GO:0046686;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;ion homeostasis#GO:0050801;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cellular divalent inorganic cation homeostasis#GO:0072503;response to toxic substance#GO:0009636;metal ion homeostasis#GO:0055065;cellular zinc ion homeostasis#GO:0006882 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12102|UniProtKB=A0A0B4J238 A0A0B4J238 TRAV1-2 PTHR19433:SF105 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 1-1-RELATED response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=33148|UniProtKB=G2XKQ0 G2XKQ0 SUMO1P1 PTHR10562:SF103 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 5 enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229;PML body#GO:0016605 HUMAN|HGNC=2093|UniProtKB=P53675 P53675 CLTCL1 PTHR10292:SF6 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN 2 protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;membrane organization#GO:0061024;organelle organization#GO:0006996;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;vesicle organization#GO:0016050;cellular component organization#GO:0016043;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;coated membrane#GO:0048475 vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 HUMAN|HGNC=16611|UniProtKB=Q5T7P3 Q5T7P3 LCE1B PTHR23263:SF142 SMALL PROLINE-RICH PROTEIN LATE CORNIFIED ENVELOPE PROTEIN 1B HUMAN|HGNC=6905|UniProtKB=Q9NZL9 Q9NZL9 MAT2B PTHR10491:SF4 DTDP-4-DEHYDRORHAMNOSE REDUCTASE METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA reductase#PC00198 O-antigen biosynthesis#P02757>dTDP-4-dehydrorhamnose reductase#P03050 HUMAN|HGNC=9958|UniProtKB=P00797 P00797 REN PTHR47966:SF24 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED RENIN blood circulation#GO:0008015;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;system process#GO:0003008;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;regulation of systemic arterial blood pressure#GO:0003073;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;circulatory system process#GO:0003013;protein processing#GO:0016485;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;regulation of blood pressure#GO:0008217;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;protein metabolic process#GO:0019538;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 HUMAN|HGNC=28701|UniProtKB=Q6ZMJ2 Q6ZMJ2 SCARA5 PTHR19331:SF472 SCAVENGER RECEPTOR DOMAIN-CONTAINING SCAVENGER RECEPTOR CLASS A MEMBER 5 serine protease#PC00203 HUMAN|HGNC=15940|UniProtKB=Q9NTW7 Q9NTW7 ZFP64 PTHR24403:SF43 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 64 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=13172|UniProtKB=O43309 O43309 ZSCAN12 PTHR23226:SF68 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 12 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=30012|UniProtKB=Q9HBH1 Q9HBH1 PDF PTHR10458:SF2 PEPTIDE DEFORMYLASE PEPTIDE DEFORMYLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 hydrolase#PC00121 HUMAN|HGNC=7907|UniProtKB=Q7Z494 Q7Z494 NPHP3 PTHR45641:SF10 TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870) NEPHROCYSTIN-3 HUMAN|HGNC=21883|UniProtKB=Q9H3E2 Q9H3E2 SNX25 PTHR22775:SF29 SORTING NEXIN SORTING NEXIN-25 scaffold/adaptor protein#PC00226 HUMAN|HGNC=29503|UniProtKB=Q96JN0 Q96JN0 LCOR PTHR21545:SF14 TRANSCRIPTION FACTOR MLR1/2 LIGAND-DEPENDENT COREPRESSOR cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=8542|UniProtKB=P51582 P51582 P2RY4 PTHR24231:SF21 PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 4 G-protein coupled receptor#PC00021 HUMAN|HGNC=11256|UniProtKB=Q13103 Q13103 SPP2 PTHR15444:SF4 SECRETED PHOSPHOPROTEIN 24 SECRETED PHOSPHOPROTEIN 24 HUMAN|HGNC=32960|UniProtKB=A6NJG2 A6NJG2 SOWAHD PTHR14491:SF8 UNCHARACTERIZED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHD HUMAN|HGNC=674|UniProtKB=P98171 P98171 ARHGAP4 PTHR14166:SF16 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 4 Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048 regulation of cellular component movement#GO:0051270;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;localization of cell#GO:0051674;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of cell motility#GO:2000146;cell migration#GO:0016477;locomotion#GO:0040011;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 GTPase-activating protein#PC00257 CCKR signaling map#P06959>ARHGAP4#P07135;PDGF signaling pathway#P00047>Rho#P01174 HUMAN|HGNC=11543|UniProtKB=Q12962 Q12962 TAF10 PTHR21242:SF0 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 general transcription factor#PC00259 HUMAN|HGNC=42937|UniProtKB=P0DME0 P0DME0 SETSIP PTHR11875:SF105 TESTIS-SPECIFIC Y-ENCODED PROTEIN PROTEIN SETSIP protein binding#GO:0005515;chromatin binding#GO:0003682;binding#GO:0005488;histone binding#GO:0042393 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=16168|UniProtKB=Q96MK2 Q96MK2 RIPOR3 PTHR15829:SF15 PROTEIN KINASE PKN/PRK1, EFFECTOR RIPOR FAMILY MEMBER 3 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=16857|UniProtKB=Q9BXK1 Q9BXK1 KLF16 PTHR23235:SF71 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 16 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=85|UniProtKB=O00763 O00763 ACACB PTHR45728:SF1 ACETYL-COA CARBOXYLASE, ISOFORM A ACETYL-COA CARBOXYLASE 2 HUMAN|HGNC=6888|UniProtKB=Q16644 Q16644 MAPKAPK3 PTHR24349:SF64 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 3 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;enzyme binding#GO:0019899;protein binding#GO:0005515;calmodulin binding#GO:0005516;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;kinase binding#GO:0019900;protein kinase activity#GO:0004672 signal transduction#GO:0007165;response to cytokine#GO:0034097;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;pattern recognition receptor signaling pathway#GO:0002221;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;protein autophosphorylation#GO:0046777;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cell communication#GO:0007154;protein phosphorylation#GO:0006468;toll-like receptor signaling pathway#GO:0002224;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to stimulus#GO:0050896;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Ras Pathway#P04393>MAPKAP#P04564;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415;Angiogenesis#P00005>MAPKAPK2/3#P00244;p38 MAPK pathway#P05918>MAPKAP-K3#P05919 HUMAN|HGNC=969|UniProtKB=Q96RK4 Q96RK4 BBS4 PTHR44186:SF1 FAMILY NOT NAMED BARDET-BIEDL SYNDROME 4 PROTEIN HUMAN|HGNC=32263|UniProtKB=P0C7V4 P0C7V4 FAM90A15P PTHR16035:SF14 PROTEIN FAM90A1 PROTEIN FAM90A10P-RELATED HUMAN|HGNC=16517|UniProtKB=Q8IU80 Q8IU80 TMPRSS6 PTHR24253:SF62 TRANSMEMBRANE PROTEASE SERINE TRANSMEMBRANE PROTEASE SERINE 6 serine protease#PC00203 HUMAN|HGNC=9869|UniProtKB=Q9UL19 Q9UL19 PLAAT4 PTHR13943:SF36 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 4 transferase activity, transferring acyl groups#GO:0016746;transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase A2 activity#GO:0004623;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase activity#GO:0004620;N-acyltransferase activity#GO:0016410 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=19940|UniProtKB=Q8NBQ7 Q8NBQ7 AQP11 PTHR21191:SF7 AQUAPORIN AQUAPORIN-11 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=23572|UniProtKB=Q14149 Q14149 MORC3 PTHR23336:SF17 ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 3 HUMAN|HGNC=9629|UniProtKB=P20962 P20962 PTMS PTHR22745:SF3 PROTHYMOSIN ALPHA PARATHYMOSIN HUMAN|HGNC=15513|UniProtKB=Q9H7B4 Q9H7B4 SMYD3 PTHR12197:SF288 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD HISTONE-LYSINE N-METHYLTRANSFERASE SMYD3 N-methyltransferase activity#GO:0008170;histone-lysine N-methyltransferase activity#GO:0018024;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone methylation#GO:0016571;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;histone lysine methylation#GO:0034968;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 histone modifying enzyme#PC00261 HUMAN|HGNC=25755|UniProtKB=Q96IZ6 Q96IZ6 METTL2A PTHR22809:SF4 METHYLTRANSFERASE-RELATED TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2A-RELATED tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 methyltransferase#PC00155 HUMAN|HGNC=25114|UniProtKB=Q96IK1 Q96IK1 BOD1 PTHR31532:SF10 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 FAMILY MEMBER BIORIENTATION OF CHROMOSOMES IN CELL DIVISION PROTEIN 1-RELATED HUMAN|HGNC=25543|UniProtKB=Q6PI26 Q6PI26 SHQ1 PTHR12967:SF0 UNCHARACTERIZED PROTEIN SHQ1 HOMOLOG protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;ribonucleoprotein complex subunit organization#GO:0071826;ribonucleoprotein complex assembly#GO:0022618;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=28643|UniProtKB=Q7Z398 Q7Z398 ZNF550 PTHR24381:SF154 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 550 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=32469|UniProtKB=Q8NE65 Q8NE65 ZNF738 PTHR23232:SF67 KRAB DOMAIN C2H2 ZINC FINGER PROTEIN ZNF738 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21474|UniProtKB=Q9NRR6 Q9NRR6 INPP5E PTHR46625:SF1 72 KDA INOSITOL POLYPHOSPHATE 5-PHOSPHATASE PHOSPHATIDYLINOSITOL POLYPHOSPHATE 5-PHOSPHATASE TYPE IV phosphatase#PC00181 HUMAN|HGNC=25538|UniProtKB=Q6PI48 Q6PI48 DARS2 PTHR22594:SF5 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, MITOCHONDRIAL aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=26401|UniProtKB=Q8N4S9 Q8N4S9 MARVELD2 PTHR23288:SF3 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL MARVEL DOMAIN-CONTAINING PROTEIN 2 general transcription factor#PC00259 HUMAN|HGNC=14772|UniProtKB=Q8NGR1 Q8NGR1 OR13A1 PTHR26452:SF125 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 13A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=9399|UniProtKB=Q05655 Q05655 PRKCD PTHR24356:SF365 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C DELTA TYPE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cell communication#GO:0007154;protein phosphorylation#GO:0006468;cellular process#GO:0009987;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;peptidyl-serine modification#GO:0018209;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>PKC#P00565;Apoptosis signaling pathway#P00006>PKCs#P00318;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;Gonadotropin-releasing hormone receptor pathway#P06664>nPKCs#P06852;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs#P06733;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>PKC#P00745;Alpha adrenergic receptor signaling pathway#P00002>PKC#P00075;Gonadotropin-releasing hormone receptor pathway#P06664>PKCs(3)#P06850;B cell activation#P00010>PKC#P00373;Endothelin signaling pathway#P00019>PKC#P00568;Angiogenesis#P00005>PKC#P00219;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;FGF signaling pathway#P00021>PKC#P00648;VEGF signaling pathway#P00056>PKC#P01425;CCKR signaling map#P06959>PKCdelta#P07134;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533 HUMAN|HGNC=15459|UniProtKB=Q9UBL9 Q9UBL9 P2RX2 PTHR10125:SF4 P2X PURINOCEPTOR P2X PURINOCEPTOR 2 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion channel activity#GO:0005216;gated channel activity#GO:0022836;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834 envelope#GO:0031975;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;nuclear membrane#GO:0031965;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;endomembrane system#GO:0012505;intracellular#GO:0005622;nuclear inner membrane#GO:0005637;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 HUMAN|HGNC=17177|UniProtKB=Q8IUI8 Q8IUI8 CRLF3 PTHR23389:SF12 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 CYTOKINE RECEPTOR-LIKE FACTOR 3 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=31979|UniProtKB=Q5SQ80 Q5SQ80 ANKRD20A2P PTHR24147:SF1 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 20A1-RELATED HUMAN|HGNC=21702|UniProtKB=Q96N11 Q96N11 C7orf26 PTHR14540:SF2 UNCHARACTERIZED SIMILAR TO PROTEIN C7ORF26 HOMOLOG HUMAN|HGNC=25153|UniProtKB=Q96EY5 Q96EY5 MVB12A PTHR31612:SF2 MULTIVESICULAR BODY SUBUNIT 12A MULTIVESICULAR BODY SUBUNIT 12A endosomal transport#GO:0016197;cellular localization#GO:0051641;signal transduction#GO:0007165;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;regulation of signaling#GO:0023051;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of signal transduction#GO:0009966;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;signaling#GO:0023052;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell communication#GO:0010646;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;epidermal growth factor receptor signaling pathway#GO:0007173;vacuolar transport#GO:0007034;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;interspecies interaction between organisms#GO:0044419;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;ERBB signaling pathway#GO:0038127;localization#GO:0051179;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;endosome transport via multivesicular body sorting pathway#GO:0032509;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cytosol#GO:0005829;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endosome membrane#GO:0010008;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ESCRT I complex#GO:0000813;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=19222|UniProtKB=Q9NYS7 Q9NYS7 WSB2 PTHR15622:SF1 WD40 REPEAT PROTEIN WD REPEAT AND SOCS BOX-CONTAINING PROTEIN 2 HUMAN|HGNC=3033|UniProtKB=P54259 P54259 ATN1 PTHR13859:SF9 ATROPHIN-RELATED ATROPHIN-1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription corepressor activity#GO:0003714;RNA polymerase II transcription factor binding#GO:0001085;protein binding#GO:0005515;molecular function regulator#GO:0098772;transcription factor binding#GO:0008134 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=15450|UniProtKB=O43493 O43493 TGOLN2 PTHR23211:SF0 TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN TGN38 TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN 2 trans-Golgi network#GO:0005802;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;clathrin-coated vesicle#GO:0030136;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;Golgi-associated vesicle#GO:0005798;transport vesicle#GO:0030133;Golgi apparatus subcompartment#GO:0098791;trans-Golgi network transport vesicle#GO:0030140;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=29384|UniProtKB=Q3MIS6 Q3MIS6 ZNF528 PTHR24377:SF918 IP01015P-RELATED ZINC FINGER PROTEIN 528 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=23483|UniProtKB=Q5JSL3 Q5JSL3 DOCK11 PTHR23317:SF81 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 11 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=11494|UniProtKB=P17600 P17600 SYN1 PTHR10841:SF24 SYNAPSIN SYNAPSIN-1 neurotransmitter secretion#GO:0007269;cellular localization#GO:0051641;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of neurotransmitter levels#GO:0001505;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;signal release#GO:0023061;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;signaling#GO:0023052;cell-cell signaling#GO:0007267;export from cell#GO:0140352;secretion by cell#GO:0032940 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synapsin#P05775 HUMAN|HGNC=3607|UniProtKB=O00757 O00757 FBP2 PTHR11556:SF13 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE ISOZYME 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 monosaccharide metabolic process#GO:0005996;carbohydrate biosynthetic process#GO:0016051;carbohydrate derivative metabolic process#GO:1901135;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular carbohydrate metabolic process#GO:0044262;oligosaccharide biosynthetic process#GO:0009312;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 carbohydrate phosphatase#PC00066 HUMAN|HGNC=4196|UniProtKB=Q14397 Q14397 GCKR PTHR10088:SF4 GLUCOKINASE REGULATORY PROTEIN GLUCOKINASE REGULATORY PROTEIN protein-binding activity modulator#PC00095 HUMAN|HGNC=20291|UniProtKB=Q86XN7 Q86XN7 PROSER1 PTHR14880:SF2 PROLINE AND SERINE-RICH PROTEIN 1 PROLINE AND SERINE-RICH PROTEIN 1 HUMAN|HGNC=20614|UniProtKB=Q8NAT2 Q8NAT2 TDRD5 PTHR22948:SF19 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 5 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3115|UniProtKB=O00716 O00716 E2F3 PTHR12081:SF44 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 p53 pathway feedback loops 2#P04398>E2F-1#P04652;p53 pathway#P00059>E2F-1#P04627;Cell cycle#P00013>E2F#P00488 HUMAN|HGNC=14596|UniProtKB=Q96QG7 Q96QG7 MTMR9 PTHR10807:SF56 MYOTUBULARIN-RELATED MYOTUBULARIN-RELATED PROTEIN 9 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;phospholipid dephosphorylation#GO:0046839;regulation of autophagy#GO:0010506;negative regulation of cellular catabolic process#GO:0031330;cellular metabolic process#GO:0044237;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;negative regulation of metabolic process#GO:0009892;negative regulation of autophagy#GO:0010507;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;primary metabolic process#GO:0044238;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;membrane#GO:0016020;intracellular#GO:0005622 phosphatase#PC00181 HUMAN|HGNC=22427|UniProtKB=A4D256 A4D256 CDC14C PTHR23339:SF117 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14C phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;regulation of mitotic nuclear division#GO:0007088;organelle localization#GO:0051640;cell projection organization#GO:0030030;membrane organization#GO:0061024;regulation of exit from mitosis#GO:0007096;nuclear division#GO:0000280;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle#GO:0045787;axoneme assembly#GO:0035082;regulation of cell division#GO:0051302;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;positive regulation of biological process#GO:0048518;regulation of cytokinesis#GO:0032465;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;positive regulation of cytokinesis#GO:0032467;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;regulation of cell cycle phase transition#GO:1901987;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;cell cycle phase transition#GO:0044770;intraciliary transport#GO:0042073;positive regulation of cellular process#GO:0048522;regulation of cell cycle process#GO:0010564;protein localization#GO:0008104;cell cycle arrest#GO:0007050;positive regulation of cell division#GO:0051781;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;cell division#GO:0051301;negative regulation of biological process#GO:0048519;mitotic cell cycle phase transition#GO:0044772;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle process#GO:1903047;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;positive regulation of cell cycle process#GO:0090068;cytoskeleton-dependent intracellular transport#GO:0030705;mitotic nuclear division#GO:0140014;protein localization to organelle#GO:0033365;negative regulation of cellular process#GO:0048523;cytokinesis#GO:0000910;membrane fission#GO:0090148;vesicle localization#GO:0051648;regulation of nuclear division#GO:0051783;negative regulation of mitotic cell cycle#GO:0045930;intraciliary transport involved in cilium assembly#GO:0035735;cellular process#GO:0009987;vesicle targeting#GO:0006903;Golgi vesicle transport#GO:0048193;cell projection assembly#GO:0030031;organelle assembly#GO:0070925;localization#GO:0051179;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;cell cycle#GO:0007049;intracellular protein transport#GO:0006886;organelle fission#GO:0048285;establishment of localization in cell#GO:0051649;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346 supramolecular complex#GO:0099080;axoneme#GO:0005930;outer dynein arm#GO:0036157;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;actin-based cell projection#GO:0098858;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;actin filament#GO:0005884;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813;stereocilium#GO:0032420;non-membrane-bounded organelle#GO:0043228;kinocilium#GO:0060091;stereocilium bundle#GO:0032421;actin cytoskeleton#GO:0015629;mitotic spindle#GO:0072686;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane region#GO:0098590;cell projection#GO:0042995;cilium#GO:0005929;spindle#GO:0005819;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;membrane-enclosed lumen#GO:0031974;spindle pole#GO:0000922;microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;organelle lumen#GO:0043233;cluster of actin-based cell projections#GO:0098862;nucleus#GO:0005634;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cytoplasmic region#GO:0099568;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;plasma membrane bounded cell projection#GO:0120025;centriole#GO:0005814;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;microtubule associated complex#GO:0005875;axonemal dynein complex#GO:0005858;protein-containing complex#GO:0032991;neuron projection#GO:0043005;ciliary basal body#GO:0036064;ciliary plasm#GO:0097014;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection cytoplasm#GO:0032838;nuclear lumen#GO:0031981;dynein complex#GO:0030286;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 protein phosphatase#PC00195 HUMAN|HGNC=29278|UniProtKB=Q9BQW3 Q9BQW3 EBF4 PTHR10747:SF36 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COE4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=1304|UniProtKB=Q8TCY5 Q8TCY5 MRAP PTHR28675:SF2 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN 2 MELANOCORTIN-2 RECEPTOR ACCESSORY PROTEIN molecular function regulator#GO:0098772;protein binding#GO:0005515;receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of catalytic activity#GO:0050790;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;protein localization to plasma membrane#GO:0072659;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;protein localization to membrane#GO:0072657;cell communication#GO:0007154;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;regulation of response to stimulus#GO:0048583;protein localization to cell periphery#GO:1990778;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=17925|UniProtKB=Q9NZI6 Q9NZI6 TFCP2L1 PTHR11037:SF18 TRANSCRIPTION FACTOR CP2 TRANSCRIPTION FACTOR CP2-LIKE PROTEIN 1 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=13244|UniProtKB=Q5C9Z4 Q5C9Z4 NOM1 PTHR18034:SF4 CELL CYCLE CONTROL PROTEIN CWF22-RELATED NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA processing factor#PC00147 HUMAN|HGNC=11430|UniProtKB=Q86Y82 Q86Y82 STX12 PTHR19957:SF88 SYNTAXIN SYNTAXIN-12 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;establishment of localization#GO:0051234;organelle organization#GO:0006996;protein transport#GO:0015031;vesicle organization#GO:0016050;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;organelle fusion#GO:0048284 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;SNARE complex#GO:0031201;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;transport vesicle membrane#GO:0030658;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;recycling endosome#GO:0055037;postsynapse#GO:0098794;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 HUMAN|HGNC=967|UniProtKB=Q9BXC9 Q9BXC9 BBS2 PTHR32465:SF0 BARDET-BIEDL SYNDROME 2 PROTEIN BARDET-BIEDL SYNDROME 2 PROTEIN vesicle targeting, to, from or within Golgi#GO:0048199;microtubule-based protein transport#GO:0099118;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;microtubule-based movement#GO:0007018;microtubule cytoskeleton organization#GO:0000226;nitrogen compound transport#GO:0071705;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;protein localization to organelle#GO:0033365;establishment of organelle localization#GO:0051656;cellular component assembly#GO:0022607;cilium assembly#GO:0060271;vesicle localization#GO:0051648;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;intraciliary transport involved in cilium assembly#GO:0035735;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;cellular process#GO:0009987;peptide transport#GO:0015833;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;transport along microtubule#GO:0010970;cell projection assembly#GO:0030031;intraciliary transport#GO:0042073;protein localization#GO:0008104;localization#GO:0051179;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based transport#GO:0099111;cellular macromolecule localization#GO:0070727;microtubule-based process#GO:0007017;protein transport along microtubule#GO:0098840;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;protein-containing complex localization#GO:0031503 microtubule organizing center#GO:0005815;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary basal body#GO:0036064;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;BBSome#GO:0034464;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=1050|UniProtKB=P55957 P55957 BID PTHR35447:SF1 BH3-INTERACTING DOMAIN DEATH AGONIST BH3-INTERACTING DOMAIN DEATH AGONIST positive regulation of cysteine-type endopeptidase activity#GO:2001056;regulation of protein metabolic process#GO:0051246;apoptotic mitochondrial changes#GO:0008637;regulation of cysteine-type endopeptidase activity#GO:2000116;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;regulation of apoptotic signaling pathway#GO:2001233;regulation of intracellular signal transduction#GO:1902531;positive regulation of proteolysis#GO:0045862;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of mitochondrion organization#GO:0010821;regulation of signal transduction#GO:0009966;proteolysis#GO:0006508;apoptotic process#GO:0006915;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;positive regulation of peptidase activity#GO:0010952;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;regulation of extrinsic apoptotic signaling pathway#GO:2001236;cellular metabolic process#GO:0044237;programmed cell death#GO:0012501;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of hydrolase activity#GO:0051345;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;intrinsic apoptotic signaling pathway#GO:0097193;apoptotic signaling pathway#GO:0097190;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of endopeptidase activity#GO:0052548;regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043281;regulation of peptidase activity#GO:0052547;positive regulation of endopeptidase activity#GO:0010950;regulation of metabolic process#GO:0019222;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0043280;signal transduction#GO:0007165;positive regulation of organelle organization#GO:0010638;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;activation of cysteine-type endopeptidase activity involved in apoptotic process#GO:0006919;positive regulation of metabolic process#GO:0009893;positive regulation of programmed cell death#GO:0043068;cell death#GO:0008219;positive regulation of intracellular signal transduction#GO:1902533;mitochondrion organization#GO:0007005;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of extrinsic apoptotic signaling pathway#GO:2001238;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;regulation of programmed cell death#GO:0043067;positive regulation of apoptotic process#GO:0043065;regulation of proteolysis#GO:0030162;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of apoptotic process#GO:0042981;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;extrinsic apoptotic signaling pathway#GO:0097191;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of cell death#GO:0010941;positive regulation of cellular component organization#GO:0051130;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell death#GO:0010942 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25607|UniProtKB=Q9NV29 Q9NV29 TMEM100 PTHR16100:SF5 PHOSPHOINOSITIDE-INTERACTING PROTEIN FAMILY MEMBER TRANSMEMBRANE PROTEIN 100 response to organic substance#GO:0010033;cellular response to BMP stimulus#GO:0071773;response to stimulus#GO:0050896;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;response to growth factor#GO:0070848;cellular response to organic substance#GO:0071310;response to BMP#GO:0071772;cellular process#GO:0009987 HUMAN|HGNC=20892|UniProtKB=Q6JVE6 Q6JVE6 LCN10 PTHR11430:SF79 LIPOCALIN EPIDIDYMAL-SPECIFIC LIPOCALIN-10 transfer/carrier protein#PC00219 HUMAN|HGNC=29026|UniProtKB=O43147 O43147 SGSM2 PTHR22957:SF194 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 2 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=44406|UniProtKB=A6NCC3 A6NCC3 GOLGA8O PTHR10881:SF62 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8H-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=29216|UniProtKB=Q2M1Z3 Q2M1Z3 ARHGAP31 PTHR15729:SF3 CDC42 GTPASE-ACTIVATING PROTEIN RHO GTPASE-ACTIVATING PROTEIN 31 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cell leading edge#GO:0031252;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 HUMAN|HGNC=33543|UniProtKB=Q6IMI6 Q6IMI6 SULT1C3 PTHR11783:SF77 SULFOTRANSFERASE SULT SULFOTRANSFERASE 1C3 transferase#PC00220 HUMAN|HGNC=16177|UniProtKB=Q8N4F0 Q8N4F0 BPIFB2 PTHR46019:SF1 BPI FOLD-CONTAINING FAMILY B MEMBER 4-RELATED BPI FOLD-CONTAINING FAMILY B MEMBER 2 HUMAN|HGNC=24866|UniProtKB=O60308 O60308 CEP104 PTHR13371:SF0 GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN CENTROSOMAL PROTEIN OF 104 KDA protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cellular anatomical entity#GO:0110165;cell projection#GO:0042995;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 HUMAN|HGNC=9310|UniProtKB=Q15173 Q15173 PPP2R5B PTHR10257:SF4 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT BETA ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;protein autophosphorylation#GO:0046777;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 HUMAN|HGNC=29576|UniProtKB=Q8TB05 Q8TB05 UBALD1 PTHR31993:SF5 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 UBA-LIKE DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=9784|UniProtKB=P61020 P61020 RAB5B PTHR24073:SF555 DRAB5-RELATED RAS-RELATED PROTEIN RAB-5B GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;membrane invagination#GO:0010324;establishment of localization#GO:0051234;vesicle organization#GO:0016050;regulation of endocytosis#GO:0030100;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;vesicle budding from membrane#GO:0006900;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;plasma membrane#GO:0005886 HUMAN|HGNC=12011|UniProtKB=P07951 P07951 TPM2 PTHR19269:SF46 TROPOMYOSIN TROPOMYOSIN BETA CHAIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 HUMAN|HGNC=4174|UniProtKB=Q92908 Q92908 GATA6 PTHR10071:SF23 TRANSCRIPTION FACTOR GATA FAMILY MEMBER TRANSCRIPTION FACTOR GATA-6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cell fate commitment#GO:0045165;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;epithelium development#GO:0060429;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell differentiation#GO:0030154;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;epithelial cell differentiation#GO:0030855;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=21571|UniProtKB=Q5VVB8 Q5VVB8 TMEM244 PTHR12952:SF1 SYS1 TRANSMEMBRANE PROTEIN 244 membrane traffic protein#PC00150 HUMAN|HGNC=8614|UniProtKB=Q96IZ0 Q96IZ0 PAWR PTHR15093:SF1 PROSTATE APOPTOSIS RESPONSE PROTEIN PAR-4 PRKC APOPTOSIS WT1 REGULATOR PROTEIN HUMAN|HGNC=19248|UniProtKB=Q8WVN8 Q8WVN8 UBE2Q2 PTHR24068:SF33 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 Q2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=16661|UniProtKB=Q8IZU2 Q8IZU2 WDR17 PTHR44464:SF1 WD REPEAT-CONTAINING PROTEIN 17 WD REPEAT-CONTAINING PROTEIN 17 HUMAN|HGNC=17190|UniProtKB=Q6UX06 Q6UX06 OLFM4 PTHR23192:SF7 OLFACTOMEDIN-RELATED OLFACTOMEDIN-4 structural protein#PC00211 HUMAN|HGNC=12138|UniProtKB=A0JD32 A0JD32 TRAV38-2DV8 PTHR23267:SF141 IMMUNOGLOBULIN LIGHT CHAIN T CELL RECEPTOR ALPHA VARIABLE 38-2/DELTA VARIABLE 8 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=10975|UniProtKB=O60721 O60721 SLC24A1 PTHR10846:SF36 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM/POTASSIUM/CALCIUM EXCHANGER 1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;antiporter activity#GO:0015297;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;channel activity#GO:0015267;cation:cation antiporter activity#GO:0015491;secondary active transmembrane transporter activity#GO:0015291;anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;solute:cation antiporter activity#GO:0015298;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;regulation of signaling#GO:0023051;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;chemical synaptic transmission#GO:0007268;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;ion homeostasis#GO:0050801;synaptic signaling#GO:0099536;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;negative regulation of signaling#GO:0023057;trans-synaptic signaling#GO:0099537;homeostatic process#GO:0042592;cell communication#GO:0007154;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;regulation of synaptic plasticity#GO:0048167;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;metal ion homeostasis#GO:0055065 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 HUMAN|HGNC=8331|UniProtKB=Q8NGR4 Q8NGR4 OR5C1 PTHR26452:SF119 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5C1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=2845|UniProtKB=P98153 P98153 DGCR2 PTHR15256:SF6 INTEGRAL MEMBRANE PROTEIN DGCR2/IDD INTEGRAL MEMBRANE PROTEIN DGCR2/IDD cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=33733|UniProtKB=A6NGA9 A6NGA9 TMEM202 PTHR10671:SF42 EPITHELIAL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 202 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=17199|UniProtKB=Q9UIG4 Q9UIG4 PSORS1C2 PTHR31853:SF1 PSORIASIS SUSCEPTIBILITY 1 CANDIDATE GENE 2 PROTEIN PSORIASIS SUSCEPTIBILITY 1 CANDIDATE GENE 2 PROTEIN HUMAN|HGNC=270|UniProtKB=P09874 P09874 PARP1 PTHR10459:SF112 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 1 transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;double-strand break repair#GO:0006302;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;response to stress#GO:0006950;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 HUMAN|HGNC=13446|UniProtKB=Q9NRM0 Q9NRM0 SLC2A9 PTHR23503:SF35 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 9 HUMAN|HGNC=5903|UniProtKB=P01714 P01714 IGLV3-19 PTHR23267:SF364 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 3-19-RELATED response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=11534|UniProtKB=Q15572 Q15572 TAF1C PTHR15319:SF1 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT C TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT C sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;core promoter sequence-specific DNA binding#GO:0001046;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;heterocyclic compound binding#GO:1901363 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription by RNA polymerase I#P00022>TAF-IC#P00649 HUMAN|HGNC=686|UniProtKB=Q15669 Q15669 RHOH PTHR24072:SF163 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOH GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;membrane organization#GO:0061024;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;phagocytosis#GO:0006909;regulation of organelle organization#GO:0033043;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;apoptotic cell clearance#GO:0043277;locomotion#GO:0040011;taxis#GO:0042330;establishment or maintenance of cell polarity#GO:0007163;neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;transport#GO:0006810;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;supramolecular fiber organization#GO:0097435;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;neuron differentiation#GO:0030182;vesicle organization#GO:0016050;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;vesicle budding from membrane#GO:0006900;regulation of developmental process#GO:0050793;motor neuron axon guidance#GO:0008045;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=6183|UniProtKB=Q15811 Q15811 ITSN1 PTHR11216:SF68 EH DOMAIN INTERSECTIN-1 molecular adaptor activity#GO:0060090;binding#GO:0005488 endosomal transport#GO:0016197;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;membrane invagination#GO:0010324;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;vesicle organization#GO:0016050;intracellular transport#GO:0046907;receptor-mediated endocytosis#GO:0006898;vesicle-mediated transport in synapse#GO:0099003 presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;synaptic membrane#GO:0097060;vesicle#GO:0031982;presynaptic membrane#GO:0042734;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;clathrin-coated pit#GO:0005905;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=21478|UniProtKB=Q8HWS3 Q8HWS3 RFX6 PTHR12619:SF28 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=6079|UniProtKB=Q92835 Q92835 INPP5D PTHR46051:SF3 SH2 DOMAIN-CONTAINING PROTEIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 5-PHOSPHATASE 1 HUMAN|HGNC=10856|UniProtKB=P14410 P14410 SI PTHR22762:SF66 ALPHA-GLUCOSIDASE SUCRASE-ISOMALTASE, INTESTINAL glucosidase#PC00108 HUMAN|HGNC=13357|UniProtKB=Q8IZK6 Q8IZK6 MCOLN2 PTHR12127:SF4 MUCOLIPIN MUCOLIPIN-2 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;lytic vacuole#GO:0000323;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=28321|UniProtKB=Q5VYY1 Q5VYY1 ANKRD22 PTHR47276:SF1 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 22 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 22 HUMAN|HGNC=5120|UniProtKB=P17482 P17482 HOXB9 PTHR45970:SF5 AGAP004664-PA HOMEOBOX PROTEIN HOX-B9 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;skeletal system development#GO:0001501;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;chordate embryonic development#GO:0043009;embryonic organ development#GO:0048568;embryo development#GO:0009790;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;embryo development ending in birth or egg hatching#GO:0009792;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;embryonic organ morphogenesis#GO:0048562;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;system development#GO:0048731;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;pattern specification process#GO:0007389;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;regulation of nucleic acid-templated transcription#GO:1903506;embryonic morphogenesis#GO:0048598;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=12510|UniProtKB=Q9H347 Q9H347 UBQLN3 PTHR10677:SF4 UBIQUILIN UBIQUILIN-3 protein binding#GO:0005515;binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=2853|UniProtKB=P49619 P49619 DGKG PTHR11255:SF36 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE GAMMA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular metabolic process#GO:0044237;cell communication#GO:0007154;lipid modification#GO:0030258;cellular process#GO:0009987;acylglycerol metabolic process#GO:0006639;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;neutral lipid metabolic process#GO:0006638;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;cellular lipid metabolic process#GO:0044255;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 kinase#PC00137 HUMAN|HGNC=6692|UniProtKB=Q07954 Q07954 LRP1 PTHR24270:SF23 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROLOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1 apolipoprotein#PC00052 Alzheimer disease-presenilin pathway#P00004>LRP N-terminal fragment#P00169;Alzheimer disease-presenilin pathway#P00004>LRP transmembrane fragment#P00152;Alzheimer disease-presenilin pathway#P00004>LRP intracellular fragment#P00173;Alzheimer disease-presenilin pathway#P00004>LRP#P00150;Alzheimer disease-presenilin pathway#P00004>LRP C-terminal fragment#P00112 HUMAN|HGNC=21096|UniProtKB=Q9NXC2 Q9NXC2 GFOD1 PTHR43818:SF2 BCDNA.GH03377 GLUCOSE-FRUCTOSE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 dehydrogenase#PC00092 HUMAN|HGNC=19848|UniProtKB=Q6ZRR7 Q6ZRR7 LRRC9 PTHR46652:SF3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED HUMAN|HGNC=11011|UniProtKB=Q9UGQ3 Q9UGQ3 SLC2A6 PTHR48021:SF59 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 6 HUMAN|HGNC=37227|UniProtKB=C9JR72 C9JR72 KBTBD13 PTHR46375:SF3 KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13-RELATED KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13 HUMAN|HGNC=29191|UniProtKB=Q9UPQ0 Q9UPQ0 LIMCH1 PTHR15551:SF3 LIM DOMAIN ONLY 7 LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;myosin binding#GO:0017022;binding#GO:0005488 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;contractile actin filament bundle assembly#GO:0030038;biological adhesion#GO:0022610;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;cell-substrate junction assembly#GO:0007044;regulation of stress fiber assembly#GO:0051492;actin filament-based process#GO:0030029;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cell junction assembly#GO:0034329;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell adhesion#GO:0030155;positive regulation of biological process#GO:0048518;cellular component assembly#GO:0022607;stress fiber assembly#GO:0043149;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;cell adhesion#GO:0007155;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;cell-matrix adhesion#GO:0007160;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;positive regulation of cytoskeleton organization#GO:0051495;regulation of cell junction assembly#GO:1901888;actin cytoskeleton organization#GO:0030036 actomyosin#GO:0042641;supramolecular complex#GO:0099080;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;stress fiber#GO:0001725;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=7189|UniProtKB=Q13875 Q13875 MOBP PTHR14555:SF6 MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED MYELIN-ASSOCIATED OLIGODENDROCYTE BASIC PROTEIN-RELATED cytoskeletal protein binding#GO:0008092;Ras GTPase binding#GO:0017016;myosin binding#GO:0017022;binding#GO:0005488;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;actin binding#GO:0003779;Rab GTPase binding#GO:0017137 cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular#GO:0005622;cytoskeleton#GO:0005856;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;intracellular organelle#GO:0043229 myelin protein#PC00161 HUMAN|HGNC=32174|UniProtKB=Q8N7U7 Q8N7U7 TPRX1 PTHR45793:SF12 HOMEOBOX PROTEIN TETRA-PEPTIDE REPEAT HOMEOBOX PROTEIN 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=3560|UniProtKB=Q01469 Q01469 FABP5 PTHR11955:SF58 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN 5 HUMAN|HGNC=21080|UniProtKB=Q7Z4G4 Q7Z4G4 TRMT11 PTHR13370:SF3 RNA METHYLASE-RELATED TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA methyltransferase#PC00033 HUMAN|HGNC=26119|UniProtKB=Q9BRV8 Q9BRV8 SIKE1 PTHR12186:SF4 SIKE FAMILY MEMBER SUPPRESSOR OF IKBKE 1 HUMAN|HGNC=2338|UniProtKB=P29762 P29762 CRABP1 PTHR11955:SF62 FATTY ACID BINDING PROTEIN CELLULAR RETINOIC ACID-BINDING PROTEIN 1 HUMAN|HGNC=30857|UniProtKB=Q96DI7 Q96DI7 SNRNP40 PTHR44006:SF1 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN mRNA splicing#P00058>U5#P01474 HUMAN|HGNC=21220|UniProtKB=Q8WXF0 Q8WXF0 SRSF12 PTHR23147:SF3 SERINE/ARGININE RICH SPLICING FACTOR SERINE/ARGININE-RICH SPLICING FACTOR 12 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=27007|UniProtKB=Q5T0D9 Q5T0D9 TPRG1L PTHR31108:SF7 TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN presynapse#GO:0098793;synapse#GO:0045202;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;cell junction#GO:0030054;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=23511|UniProtKB=Q96M53 Q96M53 TBATA PTHR33772:SF3 THYMUS, BRAIN AND TESTES-ASSOCIATED PROTEIN TBATA HUMAN|HGNC=28855|UniProtKB=Q2M218 Q2M218 ZNF630 PTHR24377:SF216 IP01015P-RELATED ZINC FINGER PROTEIN 630 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=31367|UniProtKB=Q5T6J7 Q5T6J7 IDNK PTHR43442:SF3 GLUCONOKINASE-RELATED GLUCONOKINASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carbohydrate metabolic process#GO:0005975;carboxylic acid metabolic process#GO:0019752;organic substance metabolic process#GO:0071704;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular catabolic process#GO:0044248 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 kinase#PC00137 HUMAN|HGNC=17567|UniProtKB=Q6UYE1 Q6UYE1 DLEU7 PTHR36961:SF1 LEUKEMIA-ASSOCIATED PROTEIN 7 LEUKEMIA-ASSOCIATED PROTEIN 7 HUMAN|HGNC=13205|UniProtKB=Q9C0K7 Q9C0K7 STRADB PTHR48014:SF13 SERINE/THREONINE-PROTEIN KINASE FRAY2 STE20-RELATED KINASE ADAPTER PROTEIN BETA non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=9111|UniProtKB=Q9BQD1 Q9BQD1 PMCHL2 PTHR12091:SF0 MELANIN-CONCENTRATING HORMONE PRO-MCH-RELATED protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 peptide hormone#PC00179 HUMAN|HGNC=10904|UniProtKB=Q14493 Q14493 SLBP PTHR17408:SF7 HISTONE RNA HAIRPIN-BINDING PROTEIN HISTONE RNA HAIRPIN-BINDING PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;pre-mRNA binding#GO:0036002;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;transport#GO:0006810;RNA processing#GO:0006396;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;mRNA 3'-end processing#GO:0031124;organic substance transport#GO:0071702;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;RNA transport#GO:0050658;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;establishment of RNA localization#GO:0051236;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;mRNA transport#GO:0051028;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound transport#GO:0015931;mRNA processing#GO:0006397 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=22211|UniProtKB=A0FGR8 A0FGR8 ESYT2 PTHR45761:SF2 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-2 HUMAN|HGNC=11475|UniProtKB=Q15527 Q15527 SURF2 PTHR34348:SF1 SURFEIT LOCUS PROTEIN 2 SURFEIT LOCUS PROTEIN 2 HUMAN|HGNC=27288|UniProtKB=Q4G176 Q4G176 ACSF3 PTHR24096:SF267 LONG-CHAIN-FATTY-ACID--COA LIGASE MALONATE--COA LIGASE ACSF3, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 organic acid biosynthetic process#GO:0016053;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ligase#PC00142 HUMAN|HGNC=31830|UniProtKB=Q8IYU8 Q8IYU8 MICU2 PTHR12294:SF3 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 2, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;cytosolic calcium ion transport#GO:0060401;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;mitochondrial calcium ion homeostasis#GO:0051560;mitochondrial transmembrane transport#GO:1990542;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;calcium ion import#GO:0070509;mitochondrial transport#GO:0006839;cellular chemical homeostasis#GO:0055082;mitochondrial calcium ion transmembrane transport#GO:0006851;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;transporter complex#GO:1990351;ion channel complex#GO:0034702;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cation channel complex#GO:0034703;cytoplasm#GO:0005737;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;transmembrane transporter complex#GO:1902495;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 calmodulin-related#PC00061 HUMAN|HGNC=28958|UniProtKB=Q8N1F7 Q8N1F7 NUP93 PTHR11225:SF4 NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP93 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein localization to nucleus#GO:0034504;nucleic acid transport#GO:0050657;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;ribonucleoprotein complex export from nucleus#GO:0071426;establishment of protein localization#GO:0045184;RNA localization#GO:0006403;amide transport#GO:0042886;organic substance transport#GO:0071702;protein import into nucleus#GO:0006606;mRNA-containing ribonucleoprotein complex export from nucleus#GO:0071427;establishment of localization#GO:0051234;RNA transport#GO:0050658;protein export from nucleus#GO:0006611;protein localization to organelle#GO:0033365;protein import#GO:0017038;nuclear transport#GO:0051169;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;poly(A)+ mRNA export from nucleus#GO:0016973;mRNA export from nucleus#GO:0006406;establishment of RNA localization#GO:0051236;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ribonucleoprotein complex localization#GO:0071166;peptide transport#GO:0015833;mRNA transport#GO:0051028;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;import into nucleus#GO:0051170;protein-containing complex localization#GO:0031503 envelope#GO:0031975;nuclear pore#GO:0005643;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=11556|UniProtKB=P17542 P17542 TAL1 PTHR13864:SF16 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=1989|UniProtKB=Q99426 Q99426 TBCB PTHR18916:SF79 DYNACTIN 1-RELATED MICROTUBULE-BINDING TUBULIN-FOLDING COFACTOR B cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule plus-end#GO:0035371;microtubule#GO:0005874 chaperone#PC00072 HUMAN|HGNC=3585|UniProtKB=Q9BXW9 Q9BXW9 FANCD2 PTHR32086:SF0 FANCONI ANEMIA GROUP D2 PROTEIN FANCONI ANEMIA GROUP D2 PROTEIN enzyme binding#GO:0019899;protein binding#GO:0005515;binding#GO:0005488 DNA repair#GO:0006281;homologous chromosome segregation#GO:0045143;nuclear division#GO:0000280;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;interstrand cross-link repair#GO:0036297;nitrogen compound metabolic process#GO:0006807;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;nuclear chromosome segregation#GO:0098813;meiosis I cell cycle phase#GO:0098764;negative regulation of cell cycle#GO:0045786;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;homologous chromosome pairing at meiosis#GO:0007129;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;mitotic DNA integrity checkpoint#GO:0044774;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;reproduction#GO:0000003;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;cellular aromatic compound metabolic process#GO:0006725;negative regulation of biological process#GO:0048519;DNA integrity checkpoint#GO:0031570;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;intra-S DNA damage checkpoint#GO:0031573;mitotic cell cycle process#GO:1903047;cell cycle checkpoint#GO:0000075;chromosome organization involved in meiotic cell cycle#GO:0070192;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;reciprocal meiotic recombination#GO:0007131;mitotic nuclear division#GO:0140014;DNA damage checkpoint#GO:0000077;cell cycle phase#GO:0022403;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint#GO:0007093;mitotic DNA damage checkpoint#GO:0044773;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;biological phase#GO:0044848;homologous recombination#GO:0035825;regulation of mitotic cell cycle#GO:0007346;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;condensed chromosome#GO:0000793;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=17447|UniProtKB=O94985 O94985 CLSTN1 PTHR14139:SF4 CALSYNTENIN CALSYNTENIN-1 cellular component biogenesis#GO:0044085;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;regulation of multicellular organismal development#GO:2000026;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;synaptic signaling#GO:0099536;cell junction assembly#GO:0034329;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of signaling#GO:0023056;cell-cell signaling#GO:0007267;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;regulation of multicellular organismal process#GO:0051239;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;synapse assembly#GO:0007416;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;positive regulation of cell communication#GO:0010647;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;positive regulation of synaptic transmission#GO:0050806;regulation of synapse structure or activity#GO:0050803;regulation of cell junction assembly#GO:1901888;positive regulation of multicellular organismal process#GO:0051240 cell surface#GO:0009986;synapse#GO:0045202;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;plasma membrane region#GO:0098590;postsynapse#GO:0098794;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;synaptic membrane#GO:0097060;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=16031|UniProtKB=Q96EP0 Q96EP0 RNF31 PTHR16004:SF2 RING FINGER PROTEIN 31-RELATED E3 UBIQUITIN-PROTEIN LIGASE RNF31 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=33488|UniProtKB=Q6ZUT6 Q6ZUT6 CCDC9B PTHR15635:SF10 COILED-COIL DOMAIN CONTAINING PROTEIN 9 COILED-COIL DOMAIN-CONTAINING PROTEIN 9B HUMAN|HGNC=18306|UniProtKB=Q8TAE7 Q8TAE7 KCNG3 PTHR11537:SF91 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY G MEMBER 3 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;delayed rectifier potassium channel activity#GO:0005251;ion transmembrane transporter activity#GO:0015075;voltage-gated cation channel activity#GO:0022843;voltage-gated potassium channel activity#GO:0005249;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;inorganic cation transmembrane transporter activity#GO:0022890 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813 membrane protein complex#GO:0098796;intrinsic component of membrane#GO:0031224;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;integral component of plasma membrane#GO:0005887;ion channel complex#GO:0034702;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;cation channel complex#GO:0034703;plasma membrane#GO:0005886 voltage-gated ion channel#PC00241 HUMAN|HGNC=32422|UniProtKB=Q8N4K4 Q8N4K4 RPRML PTHR28649:SF3 PROTEIN REPRIMO-RELATED REPRIMO-LIKE PROTEIN HUMAN|HGNC=17479|UniProtKB=Q96PM5 Q96PM5 RCHY1 PTHR21319:SF20 RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 P53 pathway feedback loops 1#P04392>Pirh-2#P04538;P53 pathway feedback loops 1#P04392>Pirh-2#G04684 HUMAN|HGNC=26175|UniProtKB=Q6J4K2 Q6J4K2 SLC8B1 PTHR12266:SF0 NA+/CA2+ K+ INDEPENDENT EXCHANGER MITOCHONDRIAL SODIUM/CALCIUM EXCHANGER PROTEIN ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;cation transport#GO:0006812;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810 cellular anatomical entity#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068 HUMAN|HGNC=1151|UniProtKB=O43684 O43684 BUB3 PTHR10971:SF31 MRNA EXPORT FACTOR AND BUB3 MITOTIC CHECKPOINT PROTEIN BUB3 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 negative regulation of sister chromatid segregation#GO:0033046;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome segregation#GO:0051983;nuclear division#GO:0000280;negative regulation of chromosome organization#GO:2001251;negative regulation of mitotic nuclear division#GO:0045839;regulation of cellular component organization#GO:0051128;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid segregation#GO:0033048;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of mitotic sister chromatid segregation#GO:0033047;negative regulation of cellular component organization#GO:0051129;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;mitotic sister chromatid separation#GO:0051306;sister chromatid segregation#GO:0000819;negative regulation of cell cycle#GO:0045786;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of organelle organization#GO:0033043;negative regulation of chromosome segregation#GO:0051985;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;regulation of mitotic metaphase/anaphase transition#GO:0030071;cell cycle phase transition#GO:0044770;regulation of cell cycle process#GO:0010564;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of biological process#GO:0048519;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;mitotic cell cycle phase transition#GO:0044772;regulation of chromosome separation#GO:1905818;cell cycle process#GO:0022402;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint#GO:0000075;negative regulation of organelle organization#GO:0010639;mitotic spindle assembly checkpoint#GO:0007094;mitotic nuclear division#GO:0140014;mitotic sister chromatid segregation#GO:0000070;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;mitotic cell cycle checkpoint#GO:0007093;regulation of mitotic sister chromatid separation#GO:0010965;regulation of nuclear division#GO:0051783;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;cellular process#GO:0009987;metaphase/anaphase transition of cell cycle#GO:0044784;negative regulation of chromosome separation#GO:1905819;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;cell cycle#GO:0007049;regulation of sister chromatid segregation#GO:0033045;regulation of mitotic cell cycle#GO:0007346 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular#GO:0005622;chromosome, centromeric region#GO:0000775;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=25190|UniProtKB=Q96BT1 Q96BT1 C3orf49 PTHR36473:SF1 CHROMOSOME 3 OPEN READING FRAME 49 GENE 11100-RELATED HUMAN|HGNC=17826|UniProtKB=Q86VZ2 Q86VZ2 WDR5B PTHR22847:SF516 WD40 REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 5B protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone methylation#GO:0016571;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;histone lysine methylation#GO:0034968;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;histone H3-K4 methylation#GO:0051568;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;histone methyltransferase complex#GO:0035097;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=7978|UniProtKB=P04150 P04150 NR3C1 PTHR48092:SF5 KNIRPS-RELATED PROTEIN-RELATED GLUCOCORTICOID RECEPTOR cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Gonadotropin-releasing hormone receptor pathway#P06664>GR#P06810 HUMAN|HGNC=17013|UniProtKB=O95971 O95971 CD160 PTHR15425:SF0 CD160 ANTIGEN CD160 ANTIGEN anchored component of plasma membrane#GO:0046658;intrinsic component of membrane#GO:0031224;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;anchored component of membrane#GO:0031225;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=25197|UniProtKB=Q96AQ1 Q96AQ1 CCDC74A PTHR14882:SF7 COILED-COIL DOMAIN-CONTAINING 74A COILED-COIL DOMAIN-CONTAINING PROTEIN 74A-RELATED HUMAN|Ensembl=ENSG00000225528|UniProtKB=A0A024R1R8 A0A024R1R8 ENSG00000225528 PTHR28632:SF12 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7 COILED-COIL DOMAIN-CONTAINING PROTEIN 72 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;translation#GO:0006412;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 HUMAN|HGNC=23045|UniProtKB=Q8NEN0 Q8NEN0 ARMC2 PTHR21356:SF1 ARMADILLO REPEAT CONTAINING 2 ARMADILLO REPEAT-CONTAINING PROTEIN 2 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036 HUMAN|HGNC=21166|UniProtKB=Q8TAI7 Q8TAI7 RHEBL1 PTHR24070:SF253 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTPASE RHEBL1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111 regulation of biological process#GO:0050789;small GTPase mediated signal transduction#GO:0007264;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 small GTPase#PC00208 HUMAN|HGNC=23181|UniProtKB=O43374 O43374 RASA4 PTHR10194:SF4 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 4-RELATED GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646 HUMAN|HGNC=13441|UniProtKB=Q8IWY4 Q8IWY4 SCUBE1 PTHR24046:SF4 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell surface#GO:0009986;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=15307|UniProtKB=Q8NGG6 Q8NGG6 OR8B12 PTHR48018:SF39 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8B12 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=16139|UniProtKB=Q9H1F0 Q9H1F0 WFDC10A PTHR19441:SF38 WHEY ACDIC PROTEIN WAP WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 10A serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;molecular function regulator#GO:0098772;protein binding#GO:0005515;serine-type peptidase activity#GO:0008236;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 response to external biotic stimulus#GO:0043207;immune response#GO:0006955;humoral immune response#GO:0006959;interspecies interaction between organisms#GO:0044419;antibacterial humoral response#GO:0019731;defense response to bacterium#GO:0042742;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to stress#GO:0006950;defense response to other organism#GO:0098542;antimicrobial humoral response#GO:0019730;response to other organism#GO:0051707;innate immune response#GO:0045087;defense response#GO:0006952 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=21025|UniProtKB=Q9NPB0 Q9NPB0 SAYSD1 PTHR13527:SF0 UNCHARACTERIZED SAYSVFN DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=26695|UniProtKB=Q8N9W4 Q8N9W4 GOLGA6L2 PTHR23143:SF28 TRICHOHYALIN-RELATED GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 2 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=20193|UniProtKB=A2PYH4 A2PYH4 HFM1 PTHR47961:SF7 DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED ATP-DEPENDENT DNA HELICASE HFM1-RELATED RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;nuclear division#GO:0000280;gene expression#GO:0010467;telophase#GO:0051326;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;M phase#GO:0000279;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;regulation of cellular amide metabolic process#GO:0034248;cellular protein metabolic process#GO:0044267;meiosis I#GO:0007127;organic substance metabolic process#GO:0071704;nuclear chromosome segregation#GO:0098813;chromosome separation#GO:0051304;meiosis I cell cycle phase#GO:0098764;macromolecule metabolic process#GO:0043170;meiotic cell cycle#GO:0051321;organonitrogen compound biosynthetic process#GO:1901566;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;resolution of meiotic recombination intermediates#GO:0000712;cellular component organization or biogenesis#GO:0071840;peptide biosynthetic process#GO:0043043;reproduction#GO:0000003;regulation of cellular process#GO:0050794;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;meiotic telophase I#GO:0007134;cell cycle process#GO:0022402;biosynthetic process#GO:0009058;translation#GO:0006412;meiotic chromosome separation#GO:0051307;organic cyclic compound metabolic process#GO:1901360;meiotic cell cycle process#GO:1903046;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;reciprocal meiotic recombination#GO:0007131;cell cycle phase#GO:0022403;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;meiotic chromosome segregation#GO:0045132;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular protein metabolic process#GO:0032268;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;meiotic cell cycle phase#GO:0098762;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;biological phase#GO:0044848;homologous recombination#GO:0035825;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular amide metabolic process#GO:0043603;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;intracellular#GO:0005622;cytoplasmic stress granule#GO:0010494;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464 DNA metabolism protein#PC00009 HUMAN|HGNC=30509|UniProtKB=Q8N729 Q8N729 NPW PTHR28553:SF2 NEUROPEPTIDE B NEUROPEPTIDE W protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;behavior#GO:0007610;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 HUMAN|HGNC=8126|UniProtKB=P20774 P20774 OGN PTHR46269:SF1 EPIPHYCAN-RELATED MIMECAN HUMAN|HGNC=25023|UniProtKB=Q9HBL6 Q9HBL6 LRTM1 PTHR45836:SF1 SLIT HOMOLOG LEUCINE-RICH REPEAT AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 carbohydrate derivative binding#GO:0097367;binding#GO:0005488;heparin binding#GO:0008201;protein binding#GO:0005515;anion binding#GO:0043168;ion binding#GO:0043167;glycosaminoglycan binding#GO:0005539;signaling receptor binding#GO:0005102 neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 HUMAN|HGNC=30800|UniProtKB=Q8NEW7 Q8NEW7 TMIE PTHR28635:SF1 TRANSMEMBRANE INNER EAR EXPRESSED PROTEIN TRANSMEMBRANE INNER EAR EXPRESSED PROTEIN HUMAN|HGNC=6177|UniProtKB=Q13572 Q13572 ITPK1 PTHR14217:SF25 INOSITOL-TETRAKISPHOSPHATE 1-KINASE INOSITOL-TETRAKISPHOSPHATE 1-KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 organic hydroxy compound metabolic process#GO:1901615;cellular carbohydrate metabolic process#GO:0044262;cellular metabolic process#GO:0044237;phosphorylation#GO:0016310;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 kinase#PC00137 HUMAN|HGNC=29145|UniProtKB=Q7Z7F0 Q7Z7F0 KHDC4 PTHR15744:SF0 BLOM7 KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=26656|UniProtKB=Q8IWD5 Q8IWD5 MFSD6L PTHR16172:SF22 UNCHARACTERIZED MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=29857|UniProtKB=Q9ULX6 Q9ULX6 AKAP8L PTHR12190:SF4 A-KINASE ANCHOR PROTEIN AKAP 8 A-KINASE ANCHOR PROTEIN 8-LIKE membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3279|UniProtKB=Q99613 Q99613 EIF3C PTHR13937:SF0 EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;translation initiation factor binding#GO:0031369;translation regulator activity#GO:0045182;binding#GO:0005488;organic cyclic compound binding#GO:0097159;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;translational initiation#GO:0006413;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=16656|UniProtKB=Q9GZX5 Q9GZX5 ZNF350 PTHR24404:SF11 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 350 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=17023|UniProtKB=Q8WU17 Q8WU17 RNF139 PTHR22763:SF163 RING ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF139 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;macromolecule catabolic process#GO:0009057;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;organonitrogen compound metabolic process#GO:1901564;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=24645|UniProtKB=Q5FWF5 Q5FWF5 ESCO1 PTHR45884:SF1 N-ACETYLTRANSFERASE ECO N-ACETYLTRANSFERASE ESCO1 cellular aromatic compound metabolic process#GO:0006725;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;regulation of biological process#GO:0050789;sister chromatid cohesion#GO:0007062;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nuclear chromosome segregation#GO:0098813;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;sister chromatid segregation#GO:0000819;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular component organization#GO:0016043;organic substance biosynthetic process#GO:1901576;protein acylation#GO:0043543;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;DNA biosynthetic process#GO:0071897;biological regulation#GO:0065007;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;DNA replication#GO:0006260;protein acetylation#GO:0006473;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of DNA replication#GO:0006275;regulation of cellular metabolic process#GO:0031323;DNA metabolic process#GO:0006259 acetyltransferase#PC00038 HUMAN|HGNC=13343|UniProtKB=Q6ICC9 Q6ICC9 RTL6 PTHR15503:SF30 LDOC1 RELATED RETROTRANSPOSON GAG-LIKE PROTEIN 6 HUMAN|HGNC=5401|UniProtKB=Q9HB58 Q9HB58 SP110 PTHR46386:SF7 NUCLEAR BODY PROTEIN SP140 SP110 NUCLEAR BODY PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=3347|UniProtKB=Q9Y2C4 Q9Y2C4 EXOG PTHR13966:SF5 ENDONUCLEASE RELATED NUCLEASE EXOG, MITOCHONDRIAL endonuclease activity#GO:0004519;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nuclease activity#GO:0004518;catalytic activity#GO:0003824 HUMAN|HGNC=25043|UniProtKB=Q9H7L2 Q9H7L2 KIR3DX1 PTHR11738:SF153 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR-LIKE PROTEIN KIR3DX1-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=32488|UniProtKB=Q5FYA8 Q5FYA8 ARSH PTHR42693:SF16 ARYLSULFATASE FAMILY MEMBER ARYLSULFATASE H hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 HUMAN|HGNC=11438|UniProtKB=Q13277 Q13277 STX3 PTHR19957:SF34 SYNTAXIN SYNTAXIN-3 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;regulated exocytosis#GO:0045055;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;secretion#GO:0046903;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;signal release#GO:0023061;vesicle organization#GO:0016050;cell-cell signaling#GO:0007267;signaling#GO:0023052;synaptic vesicle exocytosis#GO:0016079;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;neurotransmitter secretion#GO:0007269;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;trans-synaptic signaling#GO:0099537;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;peptide transport#GO:0015833;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;signal release from synapse#GO:0099643;exocytosis#GO:0006887;organelle organization#GO:0006996;protein localization to cell junction#GO:1902414;regulation of neurotransmitter levels#GO:0001505;protein transport#GO:0015031;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;export from cell#GO:0140352;vesicle-mediated transport in synapse#GO:0099003;protein-containing complex localization#GO:0031503 synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;SNARE complex#GO:0031201;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;presynaptic membrane#GO:0042734;vesicle#GO:0031982;intracellular organelle#GO:0043229;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;plasma membrane region#GO:0098590;postsynapse#GO:0098794;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 SNARE protein#PC00034 Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442 HUMAN|HGNC=6116|UniProtKB=P10914 P10914 IRF1 PTHR11949:SF3 INTERFERON REGULATORY FACTOR INTERFERON REGULATORY FACTOR 1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=5383|UniProtKB=P48735 P48735 IDH2 PTHR11822:SF21 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 organic hydroxy compound metabolic process#GO:1901615;oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;secondary alcohol metabolic process#GO:1902652;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;NADP metabolic process#GO:0006739;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 dehydrogenase#PC00092 HUMAN|HGNC=1246|UniProtKB=P00736 P00736 C1R PTHR24255:SF25 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED COMPLEMENT C1R SUBCOMPONENT serine-type endopeptidase activity#GO:0004252;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;gene expression#GO:0010467;protein metabolic process#GO:0019538;zymogen activation#GO:0031638;protein processing#GO:0016485;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 serine protease#PC00203 HUMAN|HGNC=28535|UniProtKB=Q8IWF9 Q8IWF9 CCDC83 PTHR21468:SF1 HSD9 COILED-COIL DOMAIN-CONTAINING PROTEIN 83 HUMAN|HGNC=117|UniProtKB=P21399 P21399 ACO1 PTHR11670:SF32 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER CYTOPLASMIC ACONITATE HYDRATASE carbon-oxygen lyase activity#GO:0016835;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;4 iron, 4 sulfur cluster binding#GO:0051539;metal cluster binding#GO:0051540;iron-sulfur cluster binding#GO:0051536;hydro-lyase activity#GO:0016836;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;lyase activity#GO:0016829;heterocyclic compound binding#GO:1901363;mRNA binding#GO:0003729 oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 HUMAN|HGNC=24973|UniProtKB=Q5SSJ5 Q5SSJ5 HP1BP3 PTHR15832:SF1 SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG HETEROCHROMATIN PROTEIN 1-BINDING PROTEIN 3 nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159;chromatin binding#GO:0003682;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;heterochromatin organization#GO:0070828;cellular process#GO:0009987;organelle organization#GO:0006996;chromosome organization#GO:0051276 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 HUMAN|HGNC=20352|UniProtKB=Q9H867 Q9H867 VCPKMT PTHR14614:SF44 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE METHYLTRANSFERASE METTL21D N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein-lysine N-methyltransferase activity#GO:0016279;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278 peptidyl-lysine modification#GO:0018205;peptidyl-lysine methylation#GO:0018022;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein alkylation#GO:0008213;protein methylation#GO:0006479;macromolecule methylation#GO:0043414;methylation#GO:0032259;nitrogen compound metabolic process#GO:0006807;peptidyl-lysine trimethylation#GO:0018023;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=18818|UniProtKB=Q8NF99 Q8NF99 ZNF397 PTHR23226:SF85 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 397 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=9288|UniProtKB=P41236 P41236 PPP1R2 PTHR12398:SF37 PROTEIN PHOSPHATASE INHIBITOR PROTEIN PHOSPHATASE INHIBITOR 2-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphatase inhibitor activity#GO:0019212;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096;protein phosphatase inhibitor activity#GO:0004864 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;regulation of phosphoprotein phosphatase activity#GO:0043666;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of phosphatase activity#GO:0010921;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 phosphatase inhibitor#PC00183 HUMAN|HGNC=4369|UniProtKB=O60547 O60547 GMDS PTHR43715:SF1 GDP-MANNOSE 4,6-DEHYDRATASE GDP-MANNOSE 4,6 DEHYDRATASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;carbohydrate derivative biosynthetic process#GO:1901137;organic cyclic compound metabolic process#GO:1901360;nucleobase-containing compound biosynthetic process#GO:0034654;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydratase#PC00091 Mannose metabolism#P02752>GDP-Mannose 4,6-dehydratase#P03015 HUMAN|Ensembl=ENSG00000276676|UniProtKB=A0A0G2JLQ3 A0A0G2JLQ3 ENSG00000276676 PTHR11738:SF168 MHC CLASS I NK CELL RECEPTOR KIR2DS5 PROTEIN-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=15198|UniProtKB=Q8NGK0 Q8NGK0 OR51G2 PTHR26450:SF133 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51G2 transmembrane signal receptor#PC00197 HUMAN|HGNC=11428|UniProtKB=O60499 O60499 STX10 PTHR19957:SF106 SYNTAXIN SYNTAXIN-10 protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;endosomal transport#GO:0016197;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;vesicle organization#GO:0016050;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;cytosolic transport#GO:0016482;protein localization#GO:0008104;retrograde transport, endosome to Golgi#GO:0042147;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;SNARE complex#GO:0031201;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;vesicle#GO:0031982;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;transport vesicle membrane#GO:0030658;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intracellular#GO:0005622;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;membrane protein complex#GO:0098796;presynapse#GO:0098793;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 SNARE protein#PC00034 Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074 HUMAN|HGNC=9903|UniProtKB=P78332 P78332 RBM6 PTHR13948:SF22 RNA-BINDING PROTEIN RNA-BINDING PROTEIN 6 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=6845|UniProtKB=Q13163 Q13163 MAP2K5 PTHR48013:SF9 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>MEK1-2#P00559;CCKR signaling map#P06959>MAP2K5#P07160 HUMAN|HGNC=9867|UniProtKB=P49788 P49788 RARRES1 PTHR28591:SF2 LATEXIN RETINOIC ACID RECEPTOR RESPONDER PROTEIN 1 metalloendopeptidase activity#GO:0004222;peptidase inhibitor activity#GO:0030414;metallopeptidase activity#GO:0008237;protease binding#GO:0002020;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase regulator activity#GO:0061135;endopeptidase inhibitor activity#GO:0004866;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function regulator#GO:0098772;protein binding#GO:0005515;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=19238|UniProtKB=Q9NYT0 Q9NYT0 PLEK2 PTHR12092:SF2 PLECKSTRIN PLECKSTRIN-2 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;actin cytoskeleton reorganization#GO:0031532;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=19918|UniProtKB=Q6NSJ0 Q6NSJ0 MYORG PTHR43053:SF4 GLYCOSIDASE FAMILY 31 MYOGENESIS-REGULATING GLYCOSIDASE glucosidase#PC00108 HUMAN|HGNC=34353|UniProtKB=Q2NKX9 Q2NKX9 C2orf68 PTHR34256:SF1 UPF0561 PROTEIN C2ORF68 UPF0561 PROTEIN C2ORF68 HUMAN|HGNC=10757|UniProtKB=P84101 P84101 SERF2 PTHR13596:SF2 SMALL EDRK-RICH FACTOR 1 SMALL EDRK-RICH FACTOR 2 HUMAN|HGNC=28407|UniProtKB=Q96HI0 Q96HI0 SENP5 PTHR12606:SF10 SENTRIN/SUMO-SPECIFIC PROTEASE SENTRIN-SPECIFIC PROTEASE 5 cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein-specific protease activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 peptidyl-lysine modification#GO:0018205;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 protease#PC00190 HUMAN|HGNC=16925|UniProtKB=Q96P48 Q96P48 ARAP1 PTHR45899:SF3 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 GTPase-activating protein#PC00257 HUMAN|HGNC=24600|UniProtKB=Q7Z6G8 Q7Z6G8 ANKS1B PTHR24174:SF3 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1B cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=31834|UniProtKB=Q96N77 Q96N77 ZNF641 PTHR24377:SF762 IP01015P-RELATED ZINC FINGER PROTEIN 641 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=26791|UniProtKB=Q5VTJ3 Q5VTJ3 KLHDC7A PTHR45972:SF1 BTB_2 DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 7A HUMAN|HGNC=20857|UniProtKB=Q9H9S0 Q9H9S0 NANOG PTHR24327:SF79 HOMEOBOX PROTEIN HOMEOBOX PROTEIN NANOG-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=12290|UniProtKB=A0A0B4J1U4 A0A0B4J1U4 TRGV5 PTHR19256:SF45 T-CELL RECEPTOR GAMMA CHAIN T CELL RECEPTOR GAMMA VARIABLE 3-RELATED HUMAN|HGNC=12504|UniProtKB=O95164 O95164 UBL3 PTHR13169:SF0 UBIQUITIN-LIKE PROTEIN 3 HCG-1 PROTEIN UBIQUITIN-LIKE PROTEIN 3 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=29096|UniProtKB=Q17R89 Q17R89 ARHGAP44 PTHR14130:SF13 3BP-1 RELATED RHOGAP RHO GTPASE-ACTIVATING PROTEIN 44 GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rho GTPase binding#GO:0017048;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;Rac GTPase binding#GO:0048365;protein binding#GO:0005515;molecular function regulator#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 endosomal transport#GO:0016197;regulation of dendrite development#GO:0050773;cellular localization#GO:0051641;cell projection organization#GO:0030030;dendrite development#GO:0016358;Ras protein signal transduction#GO:0007265;nitrogen compound transport#GO:0071705;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of intracellular signal transduction#GO:1902531;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;establishment of localization#GO:0051234;anatomical structure morphogenesis#GO:0009653;regulation of biological quality#GO:0065008;regulation of signal transduction#GO:0009966;dendritic spine organization#GO:0097061;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;protein localization to synapse#GO:0035418;regulation of dendritic spine development#GO:0060998;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;regulation of plasma membrane bounded cell projection organization#GO:0120035;peptide transport#GO:0015833;regulation of neuron differentiation#GO:0045664;protein localization#GO:0008104;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of neuron projection development#GO:0010975;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;synapse organization#GO:0050808;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;protein localization to cell junction#GO:1902414;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of cell projection organization#GO:0031344;protein transport#GO:0015031;neuron development#GO:0048666;negative regulation of signal transduction#GO:0009968;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;regulation of synapse structure or activity#GO:0050803;intracellular transport#GO:0046907;regulation of Ras protein signal transduction#GO:0046578;protein-containing complex localization#GO:0031503;regulation of dendrite morphogenesis#GO:0048814;regulation of cell morphogenesis involved in differentiation#GO:0010769;receptor localization to synapse#GO:0097120;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;neurogenesis#GO:0022008;macromolecule localization#GO:0033036;regulation of anatomical structure morphogenesis#GO:0022603;cellular protein localization#GO:0034613;negative regulation of intracellular signal transduction#GO:1902532;developmental process#GO:0032502;transport#GO:0006810;regulation of signaling#GO:0023051;cell projection morphogenesis#GO:0048858;negative regulation of Ras protein signal transduction#GO:0046580;regulation of cell differentiation#GO:0045595;regulation of multicellular organismal development#GO:2000026;amide transport#GO:0042886;cell differentiation#GO:0030154;establishment of protein localization to membrane#GO:0090150;system development#GO:0048731;organic substance transport#GO:0071702;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;regulation of actin cytoskeleton organization#GO:0032956;neuron differentiation#GO:0030182;negative regulation of small GTPase mediated signal transduction#GO:0051058;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;protein localization to plasma membrane#GO:0072659;regulation of cell communication#GO:0010646;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;protein localization to membrane#GO:0072657;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;retrograde transport, endosome to plasma membrane#GO:1990126;cellular process#GO:0009987;dendrite morphogenesis#GO:0048813;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;protein localization to cell periphery#GO:1990778;localization#GO:0051179;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;organelle organization#GO:0006996;regulation of developmental process#GO:0050793;cell junction organization#GO:0034330;biological regulation#GO:0065007;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699 presynapse#GO:0098793;synapse#GO:0045202;somatodendritic compartment#GO:0036477;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;leading edge membrane#GO:0031256;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;neuron to neuron synapse#GO:0098984;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;organelle#GO:0043226;presynaptic active zone#GO:0048786;asymmetric synapse#GO:0032279;cell leading edge#GO:0031252;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynapse#GO:0098794;neuron spine#GO:0044309;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane#GO:0005886 HUMAN|HGNC=40040|UniProtKB=A1L1A6 A1L1A6 IGSF23 PTHR44337:SF13 CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 IMMUNOGLOBULIN SUPERFAMILY MEMBER 23 HUMAN|HGNC=3335|UniProtKB=P54852 P54852 EMP3 PTHR10671:SF8 EPITHELIAL MEMBRANE PROTEIN-RELATED EPITHELIAL MEMBRANE PROTEIN 3 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 HUMAN|HGNC=18752|UniProtKB=Q9BPZ7 Q9BPZ7 MAPKAP1 PTHR13335:SF1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 phosphatidylinositol bisphosphate binding#GO:1902936;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;binding#GO:0005488;lipid binding#GO:0008289;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;ion binding#GO:0043167;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 establishment or maintenance of cell polarity#GO:0007163;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;intracellular signal transduction#GO:0035556;signaling#GO:0023052;TOR signaling#GO:0031929 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;TORC2 complex#GO:0031932;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=34342|UniProtKB=A6NHR8 A6NHR8 FAM47DP PTHR47415:SF2 PROTEIN FAM47B PROTEIN FAM47C-RELATED HUMAN|HGNC=12440|UniProtKB=P29597 P29597 TYK2 PTHR45807:SF6 TYROSINE-PROTEIN KINASE HOPSCOTCH NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>JAK#P00846 HUMAN|HGNC=7315|UniProtKB=P11836 P11836 MS4A1 PTHR23320:SF79 MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED B-LYMPHOCYTE ANTIGEN CD20 transporter#PC00227 HUMAN|HGNC=25410|UniProtKB=P0C0E4 P0C0E4 RAB40AL PTHR47980:SF43 LD44762P RAS-RELATED PROTEIN RAB-40A-LIKE vesicle fusion#GO:0006906;cellular localization#GO:0051641;organelle localization#GO:0051640;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;organelle membrane fusion#GO:0090174;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;protein secretion#GO:0009306;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;regulation of exocytosis#GO:0017157;organelle fusion#GO:0048284;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;exocytic process#GO:0140029;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;cellular macromolecule localization#GO:0070727;membrane fusion#GO:0061025;exocytosis#GO:0006887;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352 presynapse#GO:0098793;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=26780|UniProtKB=Q8N907 Q8N907 DAND5 PTHR15273:SF5 DAN DOMAIN FAMILY MEMBER 5 DAN DOMAIN FAMILY MEMBER 5 receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator#GO:0098772;protein binding#GO:0005515;signaling receptor binding#GO:0005102;receptor regulator activity#GO:0030545;binding#GO:0005488 specification of symmetry#GO:0009799;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of cellular response to growth factor stimulus#GO:0090288;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of BMP signaling pathway#GO:0030510;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;circulatory system development#GO:0072359;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;BMP signaling pathway#GO:0030509;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;activin receptor signaling pathway#GO:0032924;primary metabolic process#GO:0044238;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;mesenchyme development#GO:0060485;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090101;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of signal transduction#GO:0009968;protein localization to extracellular region#GO:0071692;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;heart development#GO:0007507;negative regulation of biological process#GO:0048519;macromolecule localization#GO:0033036;determination of heart left/right asymmetry#GO:0061371;response to growth factor#GO:0070848;RNA metabolic process#GO:0016070;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;developmental process#GO:0032502;determination of bilateral symmetry#GO:0009855;biosynthetic process#GO:0009058;regulation of multicellular organismal development#GO:2000026;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;negative regulation of multicellular organismal process#GO:0051241;response to endogenous stimulus#GO:0009719;negative regulation of BMP signaling pathway#GO:0030514;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;determination of left/right symmetry#GO:0007368;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;response to organic substance#GO:0010033;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;regulation of cell communication#GO:0010646;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;tissue development#GO:0009888;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;mesoderm development#GO:0007498;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;cellular response to growth factor stimulus#GO:0071363;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=11495|UniProtKB=Q92777 Q92777 SYN2 PTHR10841:SF20 SYNAPSIN SYNAPSIN-2 neurotransmitter secretion#GO:0007269;cellular localization#GO:0051641;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;localization#GO:0051179;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;secretion#GO:0046903;regulation of neurotransmitter levels#GO:0001505;neurotransmitter transport#GO:0006836;biological regulation#GO:0065007;signal release#GO:0023061;synaptic signaling#GO:0099536;establishment of localization in cell#GO:0051649;signaling#GO:0023052;cell-cell signaling#GO:0007267;export from cell#GO:0140352;secretion by cell#GO:0032940 synaptic vesicle membrane#GO:0030672;bounding membrane of organelle#GO:0098588;presynapse#GO:0098793;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;cell junction#GO:0030054;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;transport vesicle membrane#GO:0030658;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synapsin#P05775 HUMAN|HGNC=14512|UniProtKB=Q92552 Q92552 MRPS27 PTHR21393:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S27 28S RIBOSOMAL PROTEIN S27, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ribosomal protein#PC00202 HUMAN|HGNC=3078|UniProtKB=P33316 P33316 DUT PTHR11241:SF11 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, MITOCHONDRIAL-RELATED cation binding#GO:0043169;pyrophosphatase activity#GO:0016462;magnesium ion binding#GO:0000287;nucleoside-triphosphate diphosphatase activity#GO:0047429;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;pyrimidine nucleotide biosynthetic process#GO:0006221;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;nucleoside triphosphate catabolic process#GO:0009143;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organophosphate catabolic process#GO:0046434;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 phosphatase#PC00181 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUTP pyrophosphatase#P02918 HUMAN|HGNC=1912|UniProtKB=P28329 P28329 CHAT PTHR22589:SF14 CARNITINE O-ACYLTRANSFERASE CHOLINE O-ACETYLTRANSFERASE transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;O-acyltransferase activity#GO:0008374 trans-synaptic signaling#GO:0099537;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;anterograde trans-synaptic signaling#GO:0098916;nitrogen compound metabolic process#GO:0006807;regulation of neurotransmitter levels#GO:0001505;biological regulation#GO:0065007;synaptic signaling#GO:0099536;neuromuscular synaptic transmission#GO:0007274;signaling#GO:0023052;cell-cell signaling#GO:0007267;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;neuron projection#GO:0043005;intracellular#GO:0005622;plasma membrane region#GO:0098590;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 HUMAN|HGNC=9011|UniProtKB=Q9P0L9 Q9P0L9 PKD2L1 PTHR10877:SF187 POLYCYSTIN FAMILY MEMBER POLYCYSTIC KIDNEY DISEASE 2-LIKE 1 PROTEIN calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;cytoskeletal protein binding#GO:0008092;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;metal ion binding#GO:0046872;ion transmembrane transporter activity#GO:0015075;calcium activated cation channel activity#GO:0005227;transporter activity#GO:0005215;channel activity#GO:0015267;calcium-activated potassium channel activity#GO:0015269;cation binding#GO:0043169;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ion gated channel activity#GO:0022839;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;calcium ion binding#GO:0005509;protein binding#GO:0005515;ion binding#GO:0043167;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890 detection of mechanical stimulus#GO:0050982;monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;detection of stimulus#GO:0051606;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to mechanical stimulus#GO:0009612;establishment of localization#GO:0051234;potassium ion transmembrane transport#GO:0071805;response to abiotic stimulus#GO:0009628;potassium ion transport#GO:0006813 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133 HUMAN|HGNC=1542|UniProtKB=Q13191 Q13191 CBLB PTHR23007:SF3 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL-B transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of protein phosphorylation#GO:0001933;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;epidermal growth factor receptor signaling pathway#GO:0007173;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;negative regulation of signaling#GO:0023057;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;negative regulation of protein kinase activity#GO:0006469;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;regulation of primary metabolic process#GO:0080090;regulation of signaling receptor activity#GO:0010469;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;peptidyl-tyrosine modification#GO:0018212;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane raft#GO:0045121;membrane#GO:0016020;membrane microdomain#GO:0098857;membrane region#GO:0098589;plasma membrane#GO:0005886;whole membrane#GO:0098805 ligase#PC00142 EGF receptor signaling pathway#P00018>c-Cbl#P00544 HUMAN|GeneID=100506422|UniProtKB=Q6ZN92 Q6ZN92 - PTHR11241:SF11 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, MITOCHONDRIAL-RELATED cation binding#GO:0043169;pyrophosphatase activity#GO:0016462;magnesium ion binding#GO:0000287;nucleoside-triphosphate diphosphatase activity#GO:0047429;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;nucleoside triphosphate metabolic process#GO:0009141;pyrimidine nucleotide metabolic process#GO:0006220;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organophosphate biosynthetic process#GO:0090407;pyrimidine-containing compound metabolic process#GO:0072527;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;pyrimidine nucleotide biosynthetic process#GO:0006221;nucleoside monophosphate metabolic process#GO:0009123;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;nucleoside triphosphate catabolic process#GO:0009143;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;organophosphate catabolic process#GO:0046434;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound catabolic process#GO:0019439;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 phosphatase#PC00181 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUTP pyrophosphatase#P02918 HUMAN|HGNC=14310|UniProtKB=Q9NPI1 Q9NPI1 BRD7 PTHR22881:SF12 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN-CONTAINING PROTEIN 7 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;modification-dependent protein binding#GO:0140030 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;transcription by RNA polymerase II#GO:0006366;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|Gene=LPPR2|UniProtKB=Q96GM1 Q96GM1 PLPPR2 PTHR10165:SF15 LIPID PHOSPHATE PHOSPHATASE PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phospholipid dephosphorylation#GO:0046839;dephosphorylation#GO:0016311;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular process#GO:0009987;cellular lipid metabolic process#GO:0044255;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 phosphatase#PC00181 HUMAN|HGNC=29185|UniProtKB=Q4KWH8 Q4KWH8 PLCH1 PTHR10336:SF51 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ETA-1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phospholipase C activity#GO:0004629;phospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;inositol lipid-mediated signaling#GO:0048017;phosphatidylinositol-mediated signaling#GO:0048015;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;signaling#GO:0023052 phospholipase#PC00186 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 HUMAN|HGNC=7329|UniProtKB=P52701 P52701 MSH6 PTHR11361:SF34 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH6 mismatched DNA binding#GO:0030983;pyrophosphatase activity#GO:0016462;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;double-stranded DNA binding#GO:0003690;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;DNA-dependent ATPase activity#GO:0008094;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;mismatch repair#GO:0006298;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 mismatch repair complex#GO:0032300;protein-containing complex#GO:0032991;intracellular#GO:0005622;DNA repair complex#GO:1990391 DNA metabolism protein#PC00009 HUMAN|HGNC=25000|UniProtKB=Q7Z3V5 Q7Z3V5 ZNF571 PTHR24377:SF141 IP01015P-RELATED ZINC FINGER PROTEIN 571 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=30796|UniProtKB=Q9Y3F4 Q9Y3F4 STRAP PTHR19877:SF13 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;mRNA splicing, via spliceosome#GO:0000398;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375 SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;SMN complex#GO:0032797;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114;intracellular#GO:0005622 translation initiation factor#PC00224 HUMAN|HGNC=18704|UniProtKB=P41227 P41227 NAA10 PTHR23091:SF268 N-TERMINAL ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 10 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;N-acyltransferase activity#GO:0016410 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;N-terminal protein amino acid acetylation#GO:0006474;peptidyl-serine modification#GO:0018209;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 acetyltransferase#PC00038 HUMAN|HGNC=22984|UniProtKB=Q9NQC1 Q9NQC1 JADE2 PTHR13793:SF84 PHD FINGER PROTEINS E3 UBIQUITIN-PROTEIN LIGASE JADE-2 histone H3 acetylation#GO:0043966;peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;histone H4 acetylation#GO:0043967;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 zinc finger transcription factor#PC00244 HUMAN|HGNC=14256|UniProtKB=Q9ULD4 Q9ULD4 BRPF3 PTHR13793:SF19 PHD FINGER PROTEINS BROMODOMAIN AND PHD FINGER-CONTAINING PROTEIN 3 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;histone acetyltransferase activity#GO:0004402;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide-lysine-N-acetyltransferase activity#GO:0061733;peptide N-acetyltransferase activity#GO:0034212;binding#GO:0005488;catalytic activity#GO:0003824;protein binding#GO:0005515;histone binding#GO:0042393;N-acyltransferase activity#GO:0016410 histone H3 acetylation#GO:0043966;peptidyl-lysine acetylation#GO:0018394;peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;histone modification#GO:0016570;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular component organization#GO:0016043;covalent chromatin modification#GO:0016569;protein acylation#GO:0043543;cellular process#GO:0009987;internal peptidyl-lysine acetylation#GO:0018393;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;histone acetylation#GO:0016573;chromatin organization#GO:0006325;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;internal protein amino acid acetylation#GO:0006475 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;histone acetyltransferase complex#GO:0000123;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 zinc finger transcription factor#PC00244 HUMAN|HGNC=32486|UniProtKB=Q5QGT7 Q5QGT7 RTP2 PTHR14402:SF18 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 2 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;macromolecule localization#GO:0033036;membrane organization#GO:0061024;cellular protein localization#GO:0034613;transport#GO:0006810;system process#GO:0003008;nitrogen compound transport#GO:0071705;detection of chemical stimulus#GO:0009593;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;establishment of localization#GO:0051234;protein insertion into membrane#GO:0051205;protein localization to membrane#GO:0072657;protein targeting#GO:0006605;detection of stimulus#GO:0051606;nervous system process#GO:0050877;cellular component organization#GO:0016043;sensory perception of chemical stimulus#GO:0007606;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;protein targeting to membrane#GO:0006612;cellular macromolecule localization#GO:0070727;response to chemical#GO:0042221;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;intracellular transport#GO:0046907;sensory perception#GO:0007600 cell surface#GO:0009986;cellular anatomical entity#GO:0110165 HUMAN|HGNC=28491|UniProtKB=Q5SY80 Q5SY80 CATSPERE PTHR33722:SF3 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT EPSILON HUMAN|HGNC=7808|UniProtKB=P01138 P01138 NGF PTHR11589:SF10 NERVE GROWTH FACTOR NGF -RELATED BETA-NERVE GROWTH FACTOR receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;protein binding#GO:0005515;molecular function regulator#GO:0098772;tumor necrosis factor receptor superfamily binding#GO:0032813;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126 neuron apoptotic process#GO:0051402;regulation of protein metabolic process#GO:0051246;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;negative regulation of neuron death#GO:1901215;nervous system development#GO:0007399;regulation of biological process#GO:0050789;cognition#GO:0050890;positive regulation of cell development#GO:0010720;cellular protein metabolic process#GO:0044267;positive regulation of axonogenesis#GO:0050772;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of multicellular organismal process#GO:0051239;cellular response to endogenous stimulus#GO:0071495;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;negative regulation of cell death#GO:0060548;positive regulation of neurogenesis#GO:0050769;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;multicellular organismal process#GO:0032501;positive regulation of neuron projection development#GO:0010976;regulation of phosphorylation#GO:0042325;positive regulation of cell growth#GO:0030307;signal transduction#GO:0007165;neurogenesis#GO:0022008;negative regulation of biological process#GO:0048519;regulation of neuron death#GO:1901214;regulation of anatomical structure morphogenesis#GO:0022603;response to growth factor#GO:0070848;cellular macromolecule metabolic process#GO:0044260;behavior#GO:0007610;protein modification process#GO:0036211;growth#GO:0040007;regulation of growth#GO:0040008;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal development#GO:2000026;peptidyl-serine phosphorylation#GO:0018105;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;system development#GO:0048731;negative regulation of programmed cell death#GO:0043069;cell death#GO:0008219;neuron differentiation#GO:0030182;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of cell growth#GO:0001558;regulation of programmed cell death#GO:0043067;regulation of anatomical structure size#GO:0090066;positive regulation of protein phosphorylation#GO:0001934;developmental cell growth#GO:0048588;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cell morphogenesis involved in differentiation#GO:0000904;regulation of cell development#GO:0060284;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;nervous system process#GO:0050877;cell morphogenesis#GO:0000902;positive regulation of nervous system development#GO:0051962;cellular process#GO:0009987;regulation of cellular component size#GO:0032535;positive regulation of protein metabolic process#GO:0051247;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;response to chemical#GO:0042221;regulation of developmental process#GO:0050793;cell surface receptor signaling pathway#GO:0007166;positive regulation of cellular component organization#GO:0051130;regulation of cell death#GO:0010941;peptidyl-serine modification#GO:0018209;regulation of protein modification process#GO:0031399;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;system process#GO:0003008;positive regulation of cellular metabolic process#GO:0031325;neuron death#GO:0070997;plasma membrane bounded cell projection organization#GO:0120036;regulation of phosphorus metabolic process#GO:0051174;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;apoptotic process#GO:0006915;axonogenesis#GO:0007409;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of growth#GO:0045927;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;cellular response to organic substance#GO:0071310;regulation of neuron differentiation#GO:0045664;regulation of neuron projection development#GO:0010975;positive regulation of cellular process#GO:0048522;neuron projection development#GO:0031175;axon development#GO:0061564;positive regulation of phosphate metabolic process#GO:0045937;regulation of axonogenesis#GO:0050770;regulation of cell projection organization#GO:0031344;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;regulation of metabolic process#GO:0019222;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;regulation of cell morphogenesis involved in differentiation#GO:0010769;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of phosphate metabolic process#GO:0019220;positive regulation of cell projection organization#GO:0031346;macromolecule modification#GO:0043412;developmental process#GO:0032502;peptidyl-amino acid modification#GO:0018193;regulation of cell differentiation#GO:0045595;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of neuron differentiation#GO:0045666;developmental growth involved in morphogenesis#GO:0060560;regulation of apoptotic process#GO:0042981;positive regulation of cell differentiation#GO:0045597;developmental growth#GO:0048589;cellular response to chemical stimulus#GO:0070887;multicellular organism development#GO:0007275;cell growth#GO:0016049;positive regulation of developmental process#GO:0051094;negative regulation of apoptotic process#GO:0043066;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;biological regulation#GO:0065007;positive regulation of cellular protein metabolic process#GO:0032270;generation of neurons#GO:0048699 neurotrophic factor#PC00163 HUMAN|HGNC=21351|UniProtKB=Q5SZD1 Q5SZD1 C6orf141 PTHR36880:SF1 9130008F23RIK PROTEIN 9130008F23RIK PROTEIN HUMAN|HGNC=14395|UniProtKB=Q96T59 Q96T59 CDRT15 PTHR16471:SF3 CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN-LIKE PROTEIN CMT1A DUPLICATED REGION TRANSCRIPT 15 PROTEIN HUMAN|HGNC=12134|UniProtKB=P0DPF4 P0DPF4 TRAV35 PTHR19433:SF119 T-CELL RECEPTOR ALPHA CHAIN V REGION-RELATED T CELL RECEPTOR ALPHA VARIABLE 35 response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;response to biotic stimulus#GO:0009607;response to bacterium#GO:0009617;response to other organism#GO:0051707;interspecies interaction between organisms#GO:0044419 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=28510|UniProtKB=Q8NEA6 Q8NEA6 GLIS3 PTHR45718:SF1 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS ZINC FINGER PROTEIN GLIS3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA-binding transcription factor#PC00218 HUMAN|HGNC=19941|UniProtKB=Q8IXF9 Q8IXF9 AQP12A PTHR21191:SF8 AQUAPORIN AQUAPORIN-12A-RELATED passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=16017|UniProtKB=Q6P1L6 Q6P1L6 ZNF343 PTHR24381:SF97 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 343 DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=8396|UniProtKB=Q6IFN5 Q6IFN5 OR7E24 PTHR48001:SF47 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 7E24 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=6607|UniProtKB=O75022 O75022 LILRB3 PTHR11738:SF179 MHC CLASS I NK CELL RECEPTOR LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 6-RELATED immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=903|UniProtKB=O15169 O15169 AXIN1 PTHR46102:SF3 AXIN AXIN-1 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>Wnt Target Genes#G01558;Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Axin#P01429 HUMAN|HGNC=21533|UniProtKB=Q9Y343 Q9Y343 SNX24 PTHR15813:SF10 SORTING NEXIN-22 AND 24 SORTING NEXIN-24 scaffold/adaptor protein#PC00226 HUMAN|HGNC=27046|UniProtKB=Q86YD5 Q86YD5 LDLRAD3 PTHR24270:SF24 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 3 apolipoprotein#PC00052 HUMAN|HGNC=5010|UniProtKB=P17096 P17096 HMGA1 PTHR23341:SF9 HIGH MOBILITY GROUP PROTEINS HMG-A AND C HIGH MOBILITY GROUP PROTEIN HMG-I/HMG-Y transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 endodeoxyribonuclease#PC00093 HUMAN|HGNC=20078|UniProtKB=Q70CQ1 Q70CQ1 USP49 PTHR21646:SF7 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 49 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 cysteine protease#PC00081 HUMAN|HGNC=2097|UniProtKB=P23946 P23946 CMA1 PTHR24271:SF24 KALLIKREIN-RELATED CHYMASE intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;extracellular region#GO:0005576;secretory granule#GO:0030141;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 serine protease#PC00203 HUMAN|HGNC=3222|UniProtKB=O43921 O43921 EFNA2 PTHR11304:SF4 EPHRIN EPHRIN-A2 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 neuron projection guidance#GO:0097485;signal transduction#GO:0007165;neurogenesis#GO:0022008;cell projection organization#GO:0030030;animal organ development#GO:0048513;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;osteoclast differentiation#GO:0030316;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;hemopoiesis#GO:0030097;axonogenesis#GO:0007409;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;signaling#GO:0023052;chemotaxis#GO:0006935;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;enzyme linked receptor protein signaling pathway#GO:0007167;immune system development#GO:0002520;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;immune system process#GO:0002376;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;leukocyte differentiation#GO:0002521;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;anatomical structure development#GO:0048856;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 membrane-bound signaling molecule#PC00152 HUMAN|HGNC=14727|UniProtKB=Q8NH03 Q8NH03 OR2T3 PTHR26453:SF4 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2T3-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=20492|UniProtKB=Q96IL0 Q96IL0 COA8 PTHR31107:SF2 APOPTOGENIC PROTEIN 1, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 8 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=18281|UniProtKB=Q9BY49 Q9BY49 PECR PTHR24317:SF7 PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE reductase#PC00198 HUMAN|HGNC=24137|UniProtKB=Q6L9W6 Q6L9W6 B4GALNT3 PTHR12369:SF15 CHONDROITIN SYNTHASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE 3 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycosyltransferase#PC00111 HUMAN|HGNC=15836|UniProtKB=Q8NFJ6 Q8NFJ6 PROKR2 PTHR24241:SF125 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR PROKINETICIN RECEPTOR 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;binding#GO:0005488;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;amide binding#GO:0033218 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=12437|UniProtKB=Q16881 Q16881 TXNRD1 PTHR48105:SF7 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN REDUCTASE 1, CYTOPLASMIC disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 biological regulation#GO:0065007;regulation of biological process#GO:0050789;homeostatic process#GO:0042592;cellular process#GO:0009987;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 reductase#PC00198 HUMAN|HGNC=4414|UniProtKB=P22749 P22749 GNLY PTHR15541:SF2 GRANULYSIN RELATED GRANULYSIN HUMAN|HGNC=17180|UniProtKB=Q8WWX0 Q8WWX0 ASB5 PTHR24136:SF18 SOWAH (DROSOPHILA) HOMOLOG ANKYRIN REPEAT AND SOCS BOX PROTEIN 5 positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of catabolic process#GO:0009896;positive regulation of protein catabolic process#GO:0045732;regulation of metabolic process#GO:0019222 HUMAN|HGNC=33709|UniProtKB=Q537H7 Q537H7 SPATA45 PTHR35822:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 45 SPERMATOGENESIS-ASSOCIATED PROTEIN 45 HUMAN|HGNC=29884|UniProtKB=Q8TF42 Q8TF42 UBASH3B PTHR16469:SF29 FAMILY NOT NAMED UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING PROTEIN B phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 inorganic ion homeostasis#GO:0098771;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;divalent inorganic cation homeostasis#GO:0072507;regulation of metal ion transport#GO:0010959;regulation of sequestering of calcium ion#GO:0051282;regulation of localization#GO:0032879;tissue remodeling#GO:0048771;regulation of biological process#GO:0050789;osteoclast differentiation#GO:0030316;cellular calcium ion homeostasis#GO:0006874;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of transmembrane transport#GO:0034762;regulation of multicellular organismal process#GO:0051239;calcium ion transmembrane transport#GO:0070588;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cell adhesion#GO:0007155;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell activation#GO:0001775;regulation of ion transmembrane transport#GO:0034765;multicellular organismal homeostasis#GO:0048871;leukocyte differentiation#GO:0002521;regulation of protein phosphorylation#GO:0001932;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;calcium ion transmembrane import into cytosol#GO:0097553;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;metal ion homeostasis#GO:0055065;regulation of bone remodeling#GO:0046850;regulation of phosphorylation#GO:0042325;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;platelet activation#GO:0030168;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;biological adhesion#GO:0022610;hematopoietic or lymphoid organ development#GO:0048534;cytosolic calcium ion transport#GO:0060401;protein modification process#GO:0036211;cation transport#GO:0006812;regulation of multicellular organismal development#GO:2000026;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;sequestering of calcium ion#GO:0051208;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;negative regulation of multicellular organismal process#GO:0051241;system development#GO:0048731;divalent metal ion transport#GO:0070838;tissue homeostasis#GO:0001894;cellular divalent inorganic cation homeostasis#GO:0072503;regulation of immune system process#GO:0002682;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;negative regulation of response to stimulus#GO:0048585;transmembrane transport#GO:0055085;negative regulation of phosphorus metabolic process#GO:0010563;cell-cell adhesion#GO:0098609;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;chemical homeostasis#GO:0048878;hemostasis#GO:0007599;cellular chemical homeostasis#GO:0055082;immune system process#GO:0002376;regulation of developmental process#GO:0050793;regulation of bone resorption#GO:0045124;cell surface receptor signaling pathway#GO:0007166;maintenance of location in cell#GO:0051651;blood coagulation#GO:0007596;negative regulation of catalytic activity#GO:0043086;negative regulation of molecular function#GO:0044092;cellular localization#GO:0051641;regulation of protein modification process#GO:0031399;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;inorganic cation transmembrane transport#GO:0098662;positive regulation of cytosolic calcium ion concentration#GO:0007204;homotypic cell-cell adhesion#GO:0034109;inorganic ion transmembrane transport#GO:0098660;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein phosphorylation#GO:0001933;negative regulation of protein modification process#GO:0031400;bone remodeling#GO:0046849;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;regulation of tissue remodeling#GO:0034103;divalent inorganic cation transport#GO:0072511;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;cellular cation homeostasis#GO:0030003;immune system development#GO:0002520;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of body fluid levels#GO:0050878;release of sequestered calcium ion into cytosol#GO:0051209;regulation of calcium ion transport#GO:0051924;negative regulation of protein metabolic process#GO:0051248;regulation of cellular localization#GO:0060341;ion transmembrane transport#GO:0034220;regulation of response to stimulus#GO:0048583;calcium ion transport into cytosol#GO:0060402;response to stress#GO:0006950;response to wounding#GO:0009611;regulation of ion transport#GO:0043269;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular metal ion homeostasis#GO:0006875;negative regulation of cellular metabolic process#GO:0031324;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;animal organ development#GO:0048513;transport#GO:0006810;developmental process#GO:0032502;wound healing#GO:0042060;regulation of cell differentiation#GO:0045595;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of transport#GO:0051049;regulation of hemopoiesis#GO:1903706;ion homeostasis#GO:0050801;platelet aggregation#GO:0070527;bone resorption#GO:0045453;hemopoiesis#GO:0030097;phosphorylation#GO:0016310;negative regulation of transferase activity#GO:0051348;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;myeloid cell differentiation#GO:0030099;regulation of cation transmembrane transport#GO:1904062;multicellular organism development#GO:0007275;ion transport#GO:0006811;homeostatic process#GO:0042592;coagulation#GO:0050817;regulation of primary metabolic process#GO:0080090;localization#GO:0051179;response to stimulus#GO:0050896;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;establishment of localization in cell#GO:0051649;negative regulation of sequestering of calcium ion#GO:0051283;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=14911|UniProtKB=Q9NYW5 Q9NYW5 TAS2R4 PTHR11394:SF55 TASTE RECEPTOR TYPE 2 TASTE RECEPTOR TYPE 2 MEMBER 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;response to chemical#GO:0042221;system process#GO:0003008;detection of stimulus#GO:0051606;multicellular organismal process#GO:0032501;sensory perception#GO:0007600;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;detection of chemical stimulus#GO:0009593 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 transmembrane signal receptor#PC00197 HUMAN|HGNC=18924|UniProtKB=Q8IUC0 Q8IUC0 KRTAP13-1 PTHR19051:SF30 KERATIN-ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 13-1 structural protein#PC00211 HUMAN|HGNC=9854|UniProtKB=P46060 P46060 RANGAP1 PTHR24113:SF5 RAN GTPASE-ACTIVATING PROTEIN 1 RAN GTPASE-ACTIVATING PROTEIN 1 GTPase-activating protein#PC00257 HUMAN|HGNC=25560|UniProtKB=Q96P16 Q96P16 RPRD1A PTHR12460:SF2 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 1A basal RNA polymerase II transcription machinery binding#GO:0001099;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;basal transcription machinery binding#GO:0001098 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;mRNA 3'-end processing#GO:0031124;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;mRNA processing#GO:0006397;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase II, holoenzyme#GO:0016591;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;intracellular#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 kinase inhibitor#PC00139 HUMAN|HGNC=450|UniProtKB=Q9H161 Q9H161 ALX4 PTHR24329:SF322 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN ARISTALESS-LIKE 4 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=28598|UniProtKB=Q86XM0 Q86XM0 CATSPERD PTHR33722:SF1 CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA HUMAN|HGNC=18053|UniProtKB=Q8TDX9 Q8TDX9 PKD1L1 PTHR10877:SF145 POLYCYSTIN FAMILY MEMBER POLYCYSTIC KIDNEY DISEASE PROTEIN 1-LIKE 1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;inorganic cation transmembrane transporter activity#GO:0022890;channel activity#GO:0015267 detection of stimulus#GO:0051606;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;detection of mechanical stimulus#GO:0050982;response to mechanical stimulus#GO:0009612;response to abiotic stimulus#GO:0009628 cellular anatomical entity#GO:0110165;membrane#GO:0016020 ion channel#PC00133 HUMAN|HGNC=9114|UniProtKB=Q92871 Q92871 PMM1 PTHR10466:SF1 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE 1 isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;monosaccharide metabolic process#GO:0005996;cellular localization#GO:0051641;carbohydrate derivative metabolic process#GO:1901135;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;biosynthetic process#GO:0009058;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;protein localization to organelle#GO:0033365;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;protein localization to endoplasmic reticulum#GO:0070972;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein targeting to ER#GO:0045047;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;peptide transport#GO:0015833;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;carbohydrate derivative biosynthetic process#GO:1901137;cellular macromolecule localization#GO:0070727;protein N-linked glycosylation#GO:0006487;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;hexose metabolic process#GO:0019318;small molecule metabolic process#GO:0044281;glycosylation#GO:0070085 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 mutase#PC00160 Mannose metabolism#P02752>P-Mannose mutase#P03019 HUMAN|HGNC=12218|UniProtKB=A0A578 A0A578 TRBV5-1 PTHR23268:SF106 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 5-1 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=16990|UniProtKB=O00193 O00193 SMAP PTHR22175:SF1 SMALL ACIDIC PROTEIN-RELATED SMALL ACIDIC PROTEIN HUMAN|Ensembl=ENSG00000259916|UniProtKB=A0A075B734 A0A075B734 LOC100509620 PTHR43829:SF12 AQUAPORIN OR AQUAGLYCEROPORIN RELATED SUBFAMILY NOT NAMED amide transmembrane transporter activity#GO:0042887;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 HUMAN|HGNC=8867|UniProtKB=Q9UHV9 Q9UHV9 PFDN2 PTHR13303:SF0 PREFOLDIN SUBUNIT 2 PREFOLDIN SUBUNIT 2 protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;protein folding#GO:0006457 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=29402|UniProtKB=Q96PX1 Q96PX1 RNF157 PTHR22996:SF1 MAHOGUNIN E3 UBIQUITIN LIGASE RNF157 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=4600|UniProtKB=O00222 O00222 GRM8 PTHR24060:SF26 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR 8 adenylate cyclase activity#GO:0004016;amino acid binding#GO:0016597;signaling receptor activity#GO:0038023;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;G protein-coupled receptor activity#GO:0004930;glutamate receptor activity#GO:0008066;transmembrane signaling receptor activity#GO:0004888;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;carboxylic acid binding#GO:0031406;lyase activity#GO:0016829;molecular transducer activity#GO:0060089;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;glutamate binding#GO:0016595 regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;synaptic signaling#GO:0099536;G protein-coupled receptor signaling pathway#GO:0007186;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;signaling#GO:0023052 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Metabotropic glutamate receptor group III pathway#P00039>mGluR4/6/7/8#P01044;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 HUMAN|HGNC=14958|UniProtKB=Q8TB72 Q8TB72 PUM2 PTHR12537:SF52 RNA BINDING PROTEIN PUMILIO-RELATED PUMILIO HOMOLOG 2 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159;mRNA 3'-UTR binding#GO:0003730 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;posttranscriptional regulation of gene expression#GO:0010608;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;RNA processing#GO:0006396;gene expression#GO:0010467;post-transcriptional gene silencing by RNA#GO:0035194;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;mRNA catabolic process#GO:0006402;gene silencing#GO:0016458;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;regulation of gene expression, epigenetic#GO:0040029;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;gene silencing by miRNA#GO:0035195;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of cellular catabolic process#GO:0031329;gene silencing by RNA#GO:0031047;regulation of RNA stability#GO:0043487;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;production of miRNAs involved in gene silencing by miRNA#GO:0035196;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;posttranscriptional gene silencing#GO:0016441;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 RNA metabolism protein#PC00031 HUMAN|HGNC=28496|UniProtKB=Q7Z4H8 Q7Z4H8 POGLUT3 PTHR12203:SF18 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 3 transferase activity, transferring hexosyl groups#GO:0016758;transferase activity#GO:0016740;transferase activity, transferring glycosyl groups#GO:0016757;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=26904|UniProtKB=Q6Q4G3 Q6Q4G3 LVRN PTHR11533:SF31 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE Q cation binding#GO:0043169;metallopeptidase activity#GO:0008237;zinc ion binding#GO:0008270;binding#GO:0005488;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;amide binding#GO:0033218;peptide binding#GO:0042277;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;peptidase activity#GO:0008233;ion binding#GO:0043167;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 metalloprotease#PC00153 HUMAN|HGNC=51815|UniProtKB=A0A1W2PPM1 A0A1W2PPM1 CPHXL PTHR24341:SF1 HOMEOBOX PROTEIN ENGRAILED CYTOPLASMIC POLYADENYLATED HOMEOBOX-LIKE cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=10821|UniProtKB=Q9NP31 Q9NP31 SH2D2A PTHR14388:SF9 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN 2A cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 defense/immunity protein#PC00090 VEGF signaling pathway#P00056>VRAP#P01405;Angiogenesis#P00005>VRAP#P00196 HUMAN|HGNC=24036|UniProtKB=O95996 O95996 APC2 PTHR12607:SF3 ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY ADENOMATOUS POLYPOSIS COLI PROTEIN 2 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488;beta-catenin binding#GO:0008013 regulation of protein metabolic process#GO:0051246;regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;protein catabolic process#GO:0030163;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;microtubule polymerization or depolymerization#GO:0031109;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;nitrogen compound metabolic process#GO:0006807;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;negative regulation of cellular component organization#GO:0051129;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;macromolecule catabolic process#GO:0009057;protein-containing complex disassembly#GO:0032984;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;negative regulation of signaling#GO:0023057;localization of cell#GO:0051674;protein depolymerization#GO:0051261;cellular component organization#GO:0016043;cell communication#GO:0007154;cell fate commitment#GO:0045165;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell signaling by wnt#GO:0198738;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;positive regulation of catabolic process#GO:0009896;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of protein catabolic process#GO:0045732;locomotion#GO:0040011;regulation of metabolic process#GO:0019222;positive regulation of nitrogen compound metabolic process#GO:0051173;regulation of microtubule-based process#GO:0032886;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular protein complex disassembly#GO:0043624;microtubule depolymerization#GO:0007019;regulation of signaling#GO:0023051;developmental process#GO:0032502;microtubule cytoskeleton organization#GO:0000226;organonitrogen compound catabolic process#GO:1901565;regulation of protein catabolic process#GO:0042176;regulation of cell differentiation#GO:0045595;cell fate specification#GO:0001708;system development#GO:0048731;cell differentiation#GO:0030154;cellular component disassembly#GO:0022411;positive regulation of metabolic process#GO:0009893;negative regulation of organelle organization#GO:0010639;supramolecular fiber organization#GO:0097435;regulation of microtubule cytoskeleton organization#GO:0070507;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein metabolic process#GO:0019538;pattern specification process#GO:0007389;canonical Wnt signaling pathway#GO:0060070;signaling#GO:0023052;cell-cell signaling#GO:0007267;negative regulation of cellular process#GO:0048523;Wnt signaling pathway#GO:0016055;metabolic process#GO:0008152;regulation of cell communication#GO:0010646;cell surface receptor signaling pathway involved in cell-cell signaling#GO:1905114;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of supramolecular fiber organization#GO:1902903;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;microtubule-based process#GO:0007017;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;regulation of Wnt signaling pathway#GO:0030111;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of canonical Wnt signaling pathway#GO:0090090;cell migration#GO:0016477 supramolecular complex#GO:0099080;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cytoplasmic microtubule#GO:0005881;extrinsic component of plasma membrane#GO:0019897;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;extrinsic component of membrane#GO:0019898;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoskeleton#GO:0005856;microtubule#GO:0005874;plasma membrane#GO:0005886 Wnt signaling pathway#P00057>APC#P01468;Angiogenesis#P00005>APC#P00195 HUMAN|HGNC=17262|UniProtKB=Q9HCU9 Q9HCU9 BRMS1 PTHR21964:SF15 BREAST CANCER METASTASIS-SUPPRESSOR 1 BREAST CANCER METASTASIS-SUPPRESSOR 1 histone deacetylase binding#GO:0042826;histone deacetylase activity#GO:0004407;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;enzyme binding#GO:0019899;protein binding#GO:0005515;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 HUMAN|HGNC=11478|UniProtKB=O75683 O75683 SURF6 PTHR14369:SF0 SURFEIT LOCUS PROTEIN 6 SURFEIT LOCUS PROTEIN 6 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613 membrane-enclosed lumen#GO:0031974;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 HUMAN|HGNC=33383|UniProtKB=A0PJZ3 A0PJZ3 GXYLT2 PTHR46012:SF1 IP22168P GLUCOSIDE XYLOSYLTRANSFERASE 2 UDP-xylosyltransferase activity#GO:0035252;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity, transferring pentosyl groups#GO:0016763;transferase activity#GO:0016740;xylosyltransferase activity#GO:0042285;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 HUMAN|HGNC=25573|UniProtKB=Q8IYD2 Q8IYD2 KLHDC8A PTHR46260:SF1 RING-TYPE DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 8A HUMAN|HGNC=41906|UniProtKB=E7EW31 E7EW31 PROB1 PTHR33775:SF1 CARDIAC-ENRICHED FHL2-INTERACTING PROTEIN-RELATED PROLINE-RICH BASIC PROTEIN 1 HUMAN|HGNC=2020|UniProtKB=P51788 P51788 CLCN2 PTHR45720:SF6 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN 2 inorganic molecular entity transmembrane transporter activity#GO:0015318;anion transmembrane transporter activity#GO:0008509;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;voltage-gated ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;ion channel activity#GO:0005216;gated channel activity#GO:0022836;ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;inorganic anion transmembrane transporter activity#GO:0015103;transporter activity#GO:0005215;channel activity#GO:0015267 localization#GO:0051179;chloride transport#GO:0006821;establishment of localization#GO:0051234;anion transport#GO:0006820;inorganic anion transport#GO:0015698;ion transport#GO:0006811;transport#GO:0006810 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=18421|UniProtKB=Q9H9G7 Q9H9G7 AGO3 PTHR22891:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-3 translation initiation factor#PC00224 HUMAN|HGNC=21579|UniProtKB=Q6ZNC8 Q6ZNC8 MBOAT1 PTHR13906:SF6 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 1 transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;lipid modification#GO:0030258;cellular lipid metabolic process#GO:0044255;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 cellular anatomical entity#GO:0110165;membrane#GO:0016020 acetyltransferase#PC00038 HUMAN|HGNC=29960|UniProtKB=Q8IYS5 Q8IYS5 OSCAR PTHR11738:SF159 MHC CLASS I NK CELL RECEPTOR OSTEOCLAST-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=15152|UniProtKB=Q8NGL6 Q8NGL6 OR4A15 PTHR48002:SF79 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4A15 transmembrane signal receptor#PC00197 HUMAN|HGNC=11600|UniProtKB=Q9Y458 Q9Y458 TBX22 PTHR11267:SF116 T-BOX PROTEIN-RELATED T-BOX TRANSCRIPTION FACTOR TBX22 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;cell fate specification#GO:0001708;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;cell fate commitment#GO:0045165;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 Rel homology transcription factor#PC00252 HUMAN|HGNC=15597|UniProtKB=Q969F9 Q969F9 HPS3 PTHR28633:SF1 HERMANSKY-PUDLAK SYNDROME 3 PROTEIN HERMANSKY-PUDLAK SYNDROME 3 PROTEIN HUMAN|HGNC=9560|UniProtKB=O43242 O43242 PSMD3 PTHR10758:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;proteasome accessory complex#GO:0022624;proteasome regulatory particle#GO:0005838;intracellular#GO:0005622;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;proteasome complex#GO:0000502 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 HUMAN|HGNC=25668|UniProtKB=Q7L4P6 Q7L4P6 BEND5 PTHR14628:SF1 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN 5 HUMAN|HGNC=29251|UniProtKB=Q9P2K9 Q9P2K9 DISP3 PTHR46687:SF1 PROTEIN DISPATCHED HOMOLOG 3 PROTEIN DISPATCHED HOMOLOG 3 HUMAN|HGNC=32038|UniProtKB=Q5VUY2 Q5VUY2 AADACL4 PTHR23024:SF603 ARYLACETAMIDE DEACETYLASE ARYLACETAMIDE DEACETYLASE-LIKE 4 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 deacetylase#PC00087 HUMAN|HGNC=27455|UniProtKB=Q8IZ40 Q8IZ40 RCOR2 PTHR16089:SF12 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR 2 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;histone modification#GO:0016570;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;covalent chromatin modification#GO:0016569;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 HUMAN|HGNC=24858|UniProtKB=Q9GZY8 Q9GZY8 MFF PTHR16501:SF17 UNCHARACTERIZED MITOCHONDRIAL FISSION FACTOR cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;macromolecule localization#GO:0033036;regulation of anatomical structure morphogenesis#GO:0022603;cellular protein localization#GO:0034613;transport#GO:0006810;developmental process#GO:0032502;nitrogen compound transport#GO:0071705;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;anatomical structure morphogenesis#GO:0009653;establishment of localization#GO:0051234;regulation of mitochondrion organization#GO:0010821;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;positive regulation of biological process#GO:0048518;regulation of organelle organization#GO:0033043;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;peptide transport#GO:0015833;cellular process#GO:0009987;positive regulation of developmental process#GO:0051094;protein localization#GO:0008104;positive regulation of cellular process#GO:0048522;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;regulation of developmental process#GO:0050793;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;protein transport#GO:0015031;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;mitochondrial fission#GO:0000266 bounding membrane of organelle#GO:0098588;envelope#GO:0031975;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;integral component of mitochondrial membrane#GO:0032592;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;organelle outer membrane#GO:0031968;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;integral component of mitochondrial outer membrane#GO:0031307 HUMAN|HGNC=26061|UniProtKB=Q6IQ21 Q6IQ21 ZNF770 PTHR24376:SF205 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 770 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription activator activity#GO:0001216;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=31297|UniProtKB=A6NDL8 A6NDL8 OR6C68 PTHR26454:SF19 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 6C68 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;transmembrane signaling receptor activity#GO:0004888 transmembrane signal receptor#PC00197 HUMAN|HGNC=29580|UniProtKB=Q8WWF3 Q8WWF3 SSMEM1 PTHR31822:SF1 SERINE-RICH SINGLE-PASS MEMBRANE PROTEIN 1 SERINE-RICH SINGLE-PASS MEMBRANE PROTEIN 1 HUMAN|HGNC=17601|UniProtKB=Q8N126 Q8N126 CADM3 PTHR45889:SF5 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 3 HUMAN|HGNC=30247|UniProtKB=Q9Y6I9 Q9Y6I9 TEX264 PTHR15949:SF3 TESTIS-EXPRESSED PROTEIN 264 TESTIS-EXPRESSED PROTEIN 264 HUMAN|HGNC=44404|UniProtKB=H3BSY2 H3BSY2 GOLGA8M PTHR10881:SF62 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 8H-RELATED cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;Golgi organization#GO:0007030;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;Golgi cis cisterna#GO:0000137;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=6205|UniProtKB=P17275 P17275 JUNB PTHR11462:SF37 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JUN-B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;heterocyclic compound binding#GO:1901363;protein binding#GO:0005515;molecular function regulator#GO:0098772;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;cell population proliferation#GO:0008283;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;regulation of cell population proliferation#GO:0042127;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 basic leucine zipper transcription factor#PC00056 Gonadotropin-releasing hormone receptor pathway#P06664>JUN#P06757;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838 HUMAN|HGNC=369|UniProtKB=Q9UKA4 Q9UKA4 AKAP11 PTHR10226:SF3 A KINASE ANCHOR PROTEIN A-KINASE ANCHOR PROTEIN 11 protein kinase A binding#GO:0051018;protein binding#GO:0005515;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 scaffold/adaptor protein#PC00226 HUMAN|HGNC=32346|UniProtKB=Q5SR53 Q5SR53 PIK3CD-AS1 PTHR12138:SF119 PRIMATE-EXPANDED PROTEIN FAMILY SUBFAMILY NOT NAMED HUMAN|HGNC=25616|UniProtKB=Q96B02 Q96B02 UBE2W PTHR24068:SF153 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 W ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;protein modification process#GO:0036211;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;protein ubiquitination#GO:0016567;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular protein catabolic process#GO:0044257;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=31412|UniProtKB=Q1ZZU3 Q1ZZU3 SWI5 PTHR28529:SF2 DNA REPAIR PROTEIN SWI5 HOMOLOG DNA REPAIR PROTEIN SWI5 HOMOLOG DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;double-strand break repair#GO:0006302;cellular macromolecule metabolic process#GO:0044260;protein-containing complex assembly#GO:0065003;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;cellular response to abiotic stimulus#GO:0071214;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;recombinational repair#GO:0000725;response to abiotic stimulus#GO:0009628;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;protein-DNA complex subunit organization#GO:0071824;response to ionizing radiation#GO:0010212;cellular response to stimulus#GO:0051716;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stress#GO:0033554;cellular response to environmental stimulus#GO:0104004;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009 HUMAN|HGNC=4241|UniProtKB=Q06210 Q06210 GFPT1 PTHR10937:SF12 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 1 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;cellular aromatic compound metabolic process#GO:0006725;macromolecule glycosylation#GO:0043413;carbohydrate derivative metabolic process#GO:1901135;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;UDP-N-acetylglucosamine metabolic process#GO:0006047;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;protein N-linked glycosylation#GO:0006487;amino sugar metabolic process#GO:0006040;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;glycosylation#GO:0070085;small molecule metabolic process#GO:0044281 transaminase#PC00216 O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051;N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042 HUMAN|HGNC=21719|UniProtKB=Q01449 Q01449 MYL7 PTHR23049:SF39 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2, ATRIAL ISOFORM actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=28114|UniProtKB=Q8IZ83 Q8IZ83 ALDH16A1 PTHR11699:SF211 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402;Ornithine degradation#P02758>Aminobutyraldehyde dehydrogenase#P03055;Phenylethylamine degradation#P02766>Phenylacetaldehyde dehydrogenase#P03102 HUMAN|HGNC=16471|UniProtKB=Q9BXY5 Q9BXY5 CAPS2 PTHR34524:SF3 CALCYPHOSIN CALCYPHOSIN-2 calmodulin-related#PC00061 HUMAN|HGNC=18656|UniProtKB=Q9BRS2 Q9BRS2 RIOK1 PTHR45723:SF2 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE/THREONINE-PROTEIN KINASE RIO1 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=26527|UniProtKB=Q68CP4 Q68CP4 HGSNAT PTHR31061:SF24 LD22376P HEPARAN-ALPHA-GLUCOSAMINIDE N-ACETYLTRANSFERASE HUMAN|HGNC=25833|UniProtKB=Q6ZUS5 Q6ZUS5 CCDC121 PTHR14845:SF9 COILED-COIL DOMAIN-CONTAINING 166 COILED-COIL DOMAIN-CONTAINING PROTEIN 121 HUMAN|Ensembl=ENSG00000254469|UniProtKB=E9PQ18 E9PQ18 ENSG00000254469 PTHR11370:SF4 DNA-REPAIR PROTEIN XRCC1 XRCC1_N DOMAIN-CONTAINING PROTEIN-RELATED DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;base-excision repair#GO:0006284;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=28956|UniProtKB=Q8N335 Q8N335 GPD1L PTHR11728:SF7 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE 1-LIKE PROTEIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 carbohydrate derivative metabolic process#GO:1901135;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=22282|UniProtKB=Q5H9L2 Q5H9L2 TCEAL5 PTHR14754:SF13 TRANSCRIPTION ELONGATION FACTOR A TRANSCRIPTION ELONGATION FACTOR A PROTEIN-LIKE 5 general transcription factor#PC00259 HUMAN|HGNC=23041|UniProtKB=Q86YH6 Q86YH6 PDSS2 PTHR12001:SF55 GERANYLGERANYL PYROPHOSPHATE SYNTHASE DECAPRENYL-DIPHOSPHATE SYNTHASE SUBUNIT 2 prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;small molecule biosynthetic process#GO:0044283;ubiquinone biosynthetic process#GO:0006744;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=5974|UniProtKB=P78552 P78552 IL13RA1 PTHR23036:SF89 CYTOKINE RECEPTOR INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;cytokine receptor activity#GO:0004896;binding#GO:0005488;cytokine binding#GO:0019955;transmembrane signaling receptor activity#GO:0004888 response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;response to cytokine#GO:0034097;cellular response to chemical stimulus#GO:0070887;cellular response to organic substance#GO:0071310;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to cytokine stimulus#GO:0071345;response to chemical#GO:0042221;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cytokine-mediated signaling pathway#GO:0019221;signaling#GO:0023052 receptor complex#GO:0043235;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992 HUMAN|HGNC=29570|UniProtKB=Q9UI32 Q9UI32 GLS2 PTHR12544:SF33 GLUTAMINASE GLUTAMINASE LIVER ISOFORM, MITOCHONDRIAL hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 hydrolase#PC00121 HUMAN|HGNC=19732|UniProtKB=P0CG22 P0CG22 DHRS4L1 PTHR43943:SF1 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 4-LIKE 1-RELATED dehydrogenase#PC00092 HUMAN|HGNC=6490|UniProtKB=Q13751 Q13751 LAMB3 PTHR10574:SF268 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-3 cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cell morphogenesis involved in differentiation#GO:0000904;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;biological adhesion#GO:0022610;substrate adhesion-dependent cell spreading#GO:0034446;localization of cell#GO:0051674;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;tissue development#GO:0009888;extracellular matrix organization#GO:0030198;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;cell differentiation#GO:0030154;extracellular structure organization#GO:0043062;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;cell migration#GO:0016477;locomotion#GO:0040011 extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 HUMAN|HGNC=4110|UniProtKB=Q5JUK9 Q5JUK9 PAGE3 PTHR14047:SF1 P ANTIGEN FAMILY MEMBER 5-RELATED P ANTIGEN FAMILY MEMBER 3 HUMAN|Ensembl=ENSG00000262505|UniProtKB=A0A0G2JLG4 A0A0G2JLG4 ASIC5 PTHR11690:SF272 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED ACID-SENSING ION CHANNEL 5 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;sodium ion transmembrane transporter activity#GO:0015081;ion channel activity#GO:0005216;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated ion channel activity#GO:0015276;transmembrane transporter activity#GO:0022857;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;sodium channel activity#GO:0005272;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 localization#GO:0051179;monovalent inorganic cation transport#GO:0015672;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cation transmembrane transport#GO:0098655 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=16779|UniProtKB=Q9BYR7 Q9BYR7 KRTAP3-2 PTHR23260:SF5 KERATIN ASSOCIATED PROTEIN 3-3-RELATED KERATIN-ASSOCIATED PROTEIN 3-2 HUMAN|HGNC=10311|UniProtKB=Q02543 Q02543 RPL18A PTHR10052:SF50 60S RIBOSOMAL PROTEIN L18A 60S RIBOSOMAL PROTEIN L18A cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=20231|UniProtKB=Q9Y2U9 Q9Y2U9 KLHDC2 PTHR46228:SF3 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 2 HUMAN|HGNC=6404|UniProtKB=Q9Y664 Q9Y664 KPTN PTHR15435:SF2 KICSTOR COMPLEX PROTEIN KAPTIN KICSTOR COMPLEX PROTEIN KAPTIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;response to extracellular stimulus#GO:0009991;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;cellular response to starvation#GO:0009267;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;TOR signaling#GO:0031929;cellular response to extracellular stimulus#GO:0031668;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;TORC1 signaling#GO:0038202;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;cell communication#GO:0007154;response to nutrient levels#GO:0031667;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;cellular response to nutrient levels#GO:0031669;response to starvation#GO:0042594;biological regulation#GO:0065007;cellular response to external stimulus#GO:0071496;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;cellular response to stress#GO:0033554 supramolecular complex#GO:0099080;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;actin filament#GO:0005884;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cell leading edge#GO:0031252;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;lamellipodium#GO:0030027;plasma membrane region#GO:0098590;cell projection#GO:0042995;cytoskeleton#GO:0005856;plasma membrane#GO:0005886 HUMAN|HGNC=29469|UniProtKB=Q5TA79 Q5TA79 LCE2A PTHR23263:SF132 SMALL PROLINE-RICH PROTEIN LATE CORNIFIED ENVELOPE PROTEIN 2A-RELATED HUMAN|HGNC=9722|UniProtKB=P54886 P54886 ALDH18A1 PTHR11063:SF8 GLUTAMATE SEMIALDEHYDE DEHYDROGENASE DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 Proline biosynthesis#P02768>Glutamate semialdehyde dehydrogenase#P03112 HUMAN|HGNC=14221|UniProtKB=Q96P15 Q96P15 SERPINB11 PTHR11461:SF199 SERINE PROTEASE INHIBITOR, SERPIN SERPIN B11 serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 HUMAN|HGNC=7060|UniProtKB=P08493 P08493 MGP PTHR10109:SF0 MATRIX GLA PROTEIN MATRIX GLA PROTEIN extracellular matrix#GO:0031012;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=1173|UniProtKB=Q5H9R7 Q5H9R7 PPP6R3 PTHR12634:SF12 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 3 hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of dephosphorylation#GO:0035303;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;regulation of phosphoprotein phosphatase activity#GO:0043666;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of phosphatase activity#GO:0010921;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein dephosphorylation#GO:0006470;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of protein dephosphorylation#GO:0035304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phosphatase modulator#PC00184 HUMAN|HGNC=5107|UniProtKB=P31267 P31267 HOXA6 PTHR45659:SF14 HOMEOBOX PROTEIN HOX HOMEOBOX PROTEIN HOX-A6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;pattern specification process#GO:0007389;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;anterior/posterior pattern specification#GO:0009952;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 homeodomain transcription factor#PC00119 HUMAN|HGNC=25174|UniProtKB=Q96CS2 Q96CS2 HAUS1 PTHR31570:SF1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;spindle assembly#GO:0051225;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;spindle organization#GO:0007051;cellular process#GO:0009987 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=22180|UniProtKB=A4D2B0 A4D2B0 MBLAC1 PTHR23200:SF48 UNCHARACTERIZED METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=11729|UniProtKB=Q15554 Q15554 TERF2 PTHR46833:SF1 TELOMERIC REPEAT-BINDING FACTOR 2 TERF2 TELOMERIC REPEAT-BINDING FACTOR 2 HUMAN|HGNC=7115|UniProtKB=Q13434 Q13434 MKRN4P PTHR11224:SF53 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-4-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=12012|UniProtKB=P06753 P06753 TPM3 PTHR19269:SF38 TROPOMYOSIN TROPOMYOSIN ALPHA-3 CHAIN cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;system process#GO:0003008;actin filament organization#GO:0007015;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;muscle system process#GO:0003012;muscle contraction#GO:0006936 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 HUMAN|HGNC=15719|UniProtKB=Q5VST9 Q5VST9 OBSCN PTHR11640:SF106 NEPHRIN OBSCURIN cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=11754|UniProtKB=O14948 O14948 TFEC PTHR45776:SF1 MIP04163P TRANSCRIPTION FACTOR EC cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=14179|UniProtKB=Q9H6Q4 Q9H6Q4 CIAO3 PTHR11615:SF322 NITRATE, FORMATE, IRON DEHYDROGENASE CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 3 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 dehydrogenase#PC00092 HUMAN|HGNC=6275|UniProtKB=Q9HB14 Q9HB14 KCNK13 PTHR11003:SF57 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 13 cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;potassium channel activity#GO:0005267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;inorganic cation transmembrane transporter activity#GO:0022890 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;inorganic cation transmembrane transport#GO:0098662;ion transport#GO:0006811;transport#GO:0006810;regulation of membrane potential#GO:0042391;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;cation transmembrane transport#GO:0098655;localization#GO:0051179;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 ion channel#PC00133 HUMAN|HGNC=24548|UniProtKB=Q96IY1 Q96IY1 NSL1 PTHR31749:SF3 KINETOCHORE-ASSOCIATED PROTEIN NSL1 HOMOLOG KINETOCHORE-ASSOCIATED PROTEIN NSL1 HOMOLOG nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle#GO:0000278;chromosome organization#GO:0051276;organelle organization#GO:0006996;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cell cycle#GO:0007049;mitotic sister chromatid segregation#GO:0000070 supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular#GO:0005622;condensed chromosome#GO:0000793;condensed chromosome kinetochore#GO:0000777;condensed chromosome, centromeric region#GO:0000779;chromosome, centromeric region#GO:0000775;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=24522|UniProtKB=Q8NBN3 Q8NBN3 TMEM87A PTHR21229:SF19 LUNG SEVEN TRANSMEMBRANE RECEPTOR TRANSMEMBRANE PROTEIN 87A localization#GO:0051179;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;cellular process#GO:0009987;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147 bounding membrane of organelle#GO:0098588;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;vacuole#GO:0005773;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi stack#GO:0005795;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;Golgi membrane#GO:0000139;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=20647|UniProtKB=Q8TF45 Q8TF45 ZNF418 PTHR24377:SF759 IP01015P-RELATED ZINC FINGER PROTEIN 418 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=14833|UniProtKB=Q8NH63 Q8NH63 OR51H1 PTHR26450:SF53 OLFACTORY RECEPTOR 56B1-RELATED OLFACTORY RECEPTOR 51H1 transmembrane signal receptor#PC00197 HUMAN|HGNC=18062|UniProtKB=Q8TD30 Q8TD30 GPT2 PTHR11751:SF311 ALANINE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE 2 transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 transaminase#PC00216 HUMAN|HGNC=12221|UniProtKB=A0A0C4DH59 A0A0C4DH59 TRBV5-4 PTHR23268:SF95 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 5-4 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=30791|UniProtKB=Q9Y5Z9 Q9Y5Z9 UBIAD1 PTHR13929:SF0 1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE UBIA PRENYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;ubiquinone biosynthetic process#GO:0006744;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 transferase#PC00220 HUMAN|HGNC=9664|UniProtKB=P18433 P18433 PTPRA PTHR19134:SF433 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE ALPHA hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;phosphoric ester hydrolase activity#GO:0042578 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein phosphatase#PC00195 HUMAN|HGNC=18788|UniProtKB=P26718 P26718 KLRK1 PTHR47494:SF1 NKG2-D TYPE II INTEGRAL MEMBRANE PROTEIN NKG2-D TYPE II INTEGRAL MEMBRANE PROTEIN HUMAN|HGNC=12435|UniProtKB=P10599 P10599 TXN PTHR10438:SF18 THIOREDOXIN THIOREDOXIN oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 HUMAN|HGNC=30904|UniProtKB=O60763 O60763 USO1 PTHR10013:SF0 GENERAL VESICULAR TRANSPORT FACTOR P115 GENERAL VESICULAR TRANSPORT FACTOR P115 membrane traffic protein#PC00150 HUMAN|HGNC=26039|UniProtKB=Q9NX04 Q9NX04 C1orf109 PTHR16234:SF5 SIMILAR TO HYPOTHETICAL PROTEIN FLJ20508 SIMILAR TO HYPOTHETICAL PROTEIN FLJ20508 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=23682|UniProtKB=Q8IY26 Q8IY26 PLPP6 PTHR14969:SF18 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE PHOSPHOLIPID PHOSPHATASE 6 phosphatase#PC00181 HUMAN|HGNC=21161|UniProtKB=Q6AZZ1 Q6AZZ1 TRIM68 PTHR24103:SF89 E3 UBIQUITIN-PROTEIN LIGASE TRIM E3 UBIQUITIN-PROTEIN LIGASE TRIM68 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;protein homodimerization activity#GO:0042803;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;identical protein binding#GO:0042802;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;kinase binding#GO:0019900 regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;aromatic compound biosynthetic process#GO:0019438;positive regulation of autophagy#GO:0010508;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=30443|UniProtKB=A0ZSE6 A0ZSE6 TMEM30CP PTHR10926:SF1 CELL CYCLE CONTROL PROTEIN 50 CELL CYCLE CONTROL PROTEIN 50C organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;ion transport#GO:0006811;transport#GO:0006810;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;vacuole#GO:0005773;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=11451|UniProtKB=O14730 O14730 RIOK3 PTHR45723:SF1 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE/THREONINE-PROTEIN KINASE RIO3 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;intracellular#GO:0005622;preribosome, small subunit precursor#GO:0030688;preribosome#GO:0030684;cytosol#GO:0005829;cellular anatomical entity#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=17067|UniProtKB=Q9BWQ8 Q9BWQ8 FAIM2 PTHR23291:SF18 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 2 HUMAN|HGNC=6843|UniProtKB=P46734 P46734 MAP2K3 PTHR48013:SF21 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 3 transferase activity#GO:0016740;MAP kinase activity#GO:0004707;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein serine/threonine/tyrosine kinase activity#GO:0004712;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase activity#GO:0004708;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;regulation of intracellular signal transduction#GO:1902531;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;regulation of MAP kinase activity#GO:0043405;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;positive regulation of MAP kinase activity#GO:0043406;regulation of signaling#GO:0023051;activation of MAPK activity#GO:0000187;positive regulation of molecular function#GO:0044093;MAPK cascade#GO:0000165;protein modification process#GO:0036211;activation of protein kinase activity#GO:0032147;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;positive regulation of MAPK cascade#GO:0043410;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;regulation of protein serine/threonine kinase activity#GO:0071900;positive regulation of intracellular signal transduction#GO:1902533;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;positive regulation of protein serine/threonine kinase activity#GO:0071902;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 non-receptor serine/threonine protein kinase#PC00167 p38 MAPK pathway#P05918>MKK3#P06036;Oxidative stress response#P00046>MKK3/6#P01121;Gonadotropin-releasing hormone receptor pathway#P06664>MKK3/6#P06805;FGF signaling pathway#P00021>MKK3,6#P00625;Toll receptor signaling pathway#P00054>MKK3#P01367;EGF receptor signaling pathway#P00018>MKK3,6#P00540;Apoptosis signaling pathway#P00006>MKK3#P00314;Ras Pathway#P04393>MKK3/6#P04568;Integrin signalling pathway#P00034>MEK#P00925;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 HUMAN|HGNC=12567|UniProtKB=Q6ZN44 Q6ZN44 UNC5A PTHR12582:SF4 NETRIN RECEPTOR UNC5 NETRIN RECEPTOR UNC5A neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;axon guidance#GO:0007411;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;axonogenesis#GO:0007409;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cellular developmental process#GO:0048869;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;neuron projection development#GO:0031175;axon development#GO:0061564;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;locomotion#GO:0040011;taxis#GO:0042330 transmembrane signal receptor#PC00197 Axon guidance mediated by netrin#P00009>UNC-5#P00356 HUMAN|HGNC=19240|UniProtKB=Q86SQ3 Q86SQ3 ADGRE4P PTHR12011:SF461 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E4P-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 activation of adenylate cyclase activity#GO:0007190;regulation of lyase activity#GO:0051339;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;regulation of cyclase activity#GO:0031279;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of molecular function#GO:0065009;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;intracellular signal transduction#GO:0035556;signaling#GO:0023052;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=30338|UniProtKB=Q7Z5B4 Q7Z5B4 RIC3 PTHR21723:SF1 RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 RIC3 PROTEIN RIC-3 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cellular localization#GO:0051641;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;protein localization to cell surface#GO:0034394;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular macromolecule localization#GO:0070727;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;signaling#GO:0023052;cell-cell signaling#GO:0007267 somatodendritic compartment#GO:0036477;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular#GO:0005622;neuron projection#GO:0043005;cell body#GO:0044297;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane#GO:0005886 HUMAN|HGNC=23168|UniProtKB=Q8IYD8 Q8IYD8 FANCM PTHR14025:SF20 FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER FANCONI ANEMIA GROUP M PROTEIN DNA metabolism protein#PC00009 HUMAN|HGNC=16769|UniProtKB=Q9BQQ3 Q9BQQ3 GORASP1 PTHR12893:SF2 GOLGI REASSEMBLY STACKING PROTEIN GRASP GOLGI REASSEMBLY-STACKING PROTEIN 1 endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;Golgi organization#GO:0007030;organelle organization#GO:0006996 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=18080|UniProtKB=Q9Y274 Q9Y274 ST3GAL6 PTHR13713:SF8 SIALYLTRANSFERASE TYPE 2 LACTOSAMINE ALPHA-2,3-SIALYLTRANSFERASE transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;sialyltransferase activity#GO:0008373 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;cellular macromolecule biosynthetic process#GO:0034645;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;macromolecule modification#GO:0043412;protein glycosylation#GO:0006486;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;glycosylation#GO:0070085 transferase#PC00220 HUMAN|HGNC=30544|UniProtKB=Q96HV5 Q96HV5 TMEM41A PTHR43220:SF7 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41A HUMAN|HGNC=8850|UniProtKB=O43933 O43933 PEX1 PTHR23077:SF12 AAA-FAMILY ATPASE PEROXISOME BIOGENESIS FACTOR 1 pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;catalytic activity#GO:0003824;ATPase activity#GO:0016887 cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;protein import into peroxisome matrix#GO:0016558;transport#GO:0006810;protein transmembrane transport#GO:0071806;nitrogen compound transport#GO:0071705;protein targeting to peroxisome#GO:0006625;protein transmembrane import into intracellular organelle#GO:0044743;establishment of protein localization#GO:0045184;amide transport#GO:0042886;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;protein import#GO:0017038;protein localization to peroxisome#GO:0072662;transmembrane transport#GO:0055085;protein targeting#GO:0006605;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;peptide transport#GO:0015833;cellular process#GO:0009987;protein localization#GO:0008104;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to peroxisome#GO:0072663;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;protein transport#GO:0015031;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;microbody membrane#GO:0031903;intracellular#GO:0005622;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777 HUMAN|HGNC=11325|UniProtKB=Q9UNL2 Q9UNL2 SSR3 PTHR13399:SF2 TRANSLOCON-ASSOCIATED PROTEIN TRAP , GAMMA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT GAMMA cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=12624|UniProtKB=Q9UHP3 Q9UHP3 USP25 PTHR24006:SF666 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 25 thiol-dependent ubiquitin-specific protease activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitinyl hydrolase activity#GO:0101005;omega peptidase activity#GO:0008242;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein modification by small protein removal#GO:0070646;proteolysis#GO:0006508;protein deubiquitination#GO:0016579;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 cysteine protease#PC00081 HUMAN|HGNC=9700|UniProtKB=Q8IVU1 Q8IVU1 IGDCC3 PTHR44170:SF20 PROTEIN SIDEKICK IMMUNOGLOBULIN SUPERFAMILY DCC SUBCLASS MEMBER 3 HUMAN|HGNC=11343|UniProtKB=P50502 P50502 ST13 PTHR45883:SF6 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN-RELATED protein binding#GO:0005515;heat shock protein binding#GO:0031072;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;chaperone-mediated protein folding#GO:0061077;protein folding#GO:0006457;protein-containing complex assembly#GO:0065003;'de novo' protein folding#GO:0006458;cellular component organization#GO:0016043;cellular process#GO:0009987;protein-containing complex subunit organization#GO:0043933 HUMAN|HGNC=813|UniProtKB=Q93084 Q93084 ATP2A3 PTHR42861:SF6 CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 3 calcium ion transmembrane transporter activity#GO:0015085;inorganic molecular entity transmembrane transporter activity#GO:0015318;catalytic activity#GO:0003824;cation transmembrane transporter activity#GO:0008324;monovalent inorganic cation transmembrane transporter activity#GO:0015077;ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;pyrophosphatase activity#GO:0016462;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;metal ion transmembrane transporter activity#GO:0046873;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111;inorganic cation transmembrane transporter activity#GO:0022890;active ion transmembrane transporter activity#GO:0022853;ATPase activity#GO:0016887 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;cellular process#GO:0009987;chemical homeostasis#GO:0048878;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;cellular chemical homeostasis#GO:0055082;localization#GO:0051179;biological regulation#GO:0065007;metal ion homeostasis#GO:0055065 bounding membrane of organelle#GO:0098588;sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;sarcoplasmic reticulum membrane#GO:0033017;sarcoplasm#GO:0016528;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 primary active transporter#PC00068 HUMAN|HGNC=19953|UniProtKB=Q8IWX5 Q8IWX5 SGPP2 PTHR14969:SF14 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 organic hydroxy compound metabolic process#GO:1901615;phospholipid dephosphorylation#GO:0046839;lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;alcohol metabolic process#GO:0006066;lipid modification#GO:0030258;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;dephosphorylation#GO:0016311;cellular lipid metabolic process#GO:0044255;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 phosphatase#PC00181 HUMAN|HGNC=29450|UniProtKB=Q9BZE0 Q9BZE0 GLIS2 PTHR19818:SF84 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN GLIS2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;central nervous system development#GO:0007417;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;multicellular organism development#GO:0007275;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=23479|UniProtKB=Q96BY6 Q96BY6 DOCK10 PTHR23317:SF71 DEDICATOR OF CYTOKINESIS DOCK DEDICATOR OF CYTOKINESIS PROTEIN 10 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=3972|UniProtKB=Q12841 Q12841 FSTL1 PTHR10913:SF13 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 1-RELATED signal transduction#GO:0007165;response to growth factor#GO:0070848;developmental process#GO:0032502;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of BMP signaling pathway#GO:0030510;cellular response to BMP stimulus#GO:0071773;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;response to BMP#GO:0071772;signaling#GO:0023052;response to organic substance#GO:0010033;cellular developmental process#GO:0048869;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;BMP signaling pathway#GO:0030509;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;response to chemical#GO:0042221;cellular response to growth factor stimulus#GO:0071363;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 protease inhibitor#PC00191 Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Cadherin signaling pathway#P00012>Wnt#P00474 HUMAN|HGNC=29455|UniProtKB=Q6UX27 Q6UX27 VSTM1 PTHR11738:SF180 MHC CLASS I NK CELL RECEPTOR V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=22966|UniProtKB=P60331 P60331 KRTAP10-1 PTHR23262:SF175 KERATIN ASSOCIATED PROTEIN KERATIN-ASSOCIATED PROTEIN 10-1-RELATED HUMAN|HGNC=8976|UniProtKB=P42338 P42338 PIK3CB PTHR10048:SF33 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA ISOFORM transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;kinase activity#GO:0016301 lipid metabolic process#GO:0006629;signal transduction#GO:0007165;phospholipid biosynthetic process#GO:0008654;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;lipid modification#GO:0030258;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;phosphatidylinositol-mediated signaling#GO:0048015;phosphorylation#GO:0016310;intracellular signal transduction#GO:0035556;signaling#GO:0023052;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular response to stimulus#GO:0051716;glycerolipid biosynthetic process#GO:0045017;localization of cell#GO:0051674;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cell communication#GO:0007154;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cell motility#GO:0048870;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;response to stimulus#GO:0050896;phosphatidylinositol 3-kinase signaling#GO:0014065;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;inositol lipid-mediated signaling#GO:0048017;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;cell migration#GO:0016477;locomotion#GO:0040011;phosphatidylinositol phosphorylation#GO:0046854 cytoplasm#GO:0005737;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;phosphatidylinositol 3-kinase complex#GO:0005942;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898 kinase#PC00137 PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;CCKR signaling map#P06959>p110#P07020;T cell activation#P00053>PI3K#P01322;Hypoxia response via HIF activation#P00030>PI3K#P00823;Axon guidance mediated by netrin#P00009>PI3K#P00363;PI3 kinase pathway#P00048>p110#P01192;EGF receptor signaling pathway#P00018>PI3K#P00557;VEGF signaling pathway#P00056>PI3K#P01413;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;Endothelin signaling pathway#P00019>PI3K#P00577;Integrin signalling pathway#P00034>PI3K#P00936;Angiogenesis#P00005>PI3K#P00236;B cell activation#P00010>PI3K#P00391;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;p53 pathway#P00059>PI3K#P04609;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Interleukin signaling pathway#P00036>PI3K#P00990;PI3 kinase pathway#P00048>P110ACT#P01177 HUMAN|HGNC=14975|UniProtKB=Q9Y5W9 Q9Y5W9 SNX11 PTHR46209:SF1 PX DOMAIN-CONTAINING PROTEIN SORTING NEXIN-11 HUMAN|HGNC=7410|UniProtKB=Q13330 Q13330 MTA1 PTHR10865:SF5 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA1 repressing transcription factor binding#GO:0070491;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;histone deacetylase binding#GO:0042826;transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription coactivator activity#GO:0003713;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;transcription factor binding#GO:0008134;DNA-binding transcription factor binding#GO:0140297 DNA repair#GO:0006281;negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;histone deacetylation#GO:0016575;response to abiotic stimulus#GO:0009628;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;response to ionizing radiation#GO:0010212;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;cellular response to DNA damage stimulus#GO:0006974;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;protein deacetylation#GO:0006476;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;response to radiation#GO:0009314;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;macromolecule deacylation#GO:0098732;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;protein deacylation#GO:0035601;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;transcription repressor complex#GO:0017053;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;chromosome#GO:0005694;intracellular#GO:0005622;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=16835|UniProtKB=Q9UL54 Q9UL54 TAOK2 PTHR48015:SF7 SERINE/THREONINE-PROTEIN KINASE TAO SERINE/THREONINE-PROTEIN KINASE TAO2 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;MAPK cascade#GO:0000165;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;regulation of primary metabolic process#GO:0080090;cell development#GO:0048468;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=5658|UniProtKB=A0A075B7B6 A0A075B7B6 IGHV4OR15-8 PTHR23266:SF364 IMMUNOGLOBULIN HEAVY CHAIN IG-LIKE DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=6771|UniProtKB=Q99717 Q99717 SMAD5 PTHR13703:SF36 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 5 DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;SMAD binding#GO:0046332;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;double-stranded DNA binding#GO:0003690;transcription factor binding#GO:0008134;ubiquitin protein ligase binding#GO:0031625;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;transforming growth factor beta receptor signaling pathway#GO:0007179;nucleobase-containing compound metabolic process#GO:0006139;response to transforming growth factor beta#GO:0071559;cellular response to transforming growth factor beta stimulus#GO:0071560;regulation of biological process#GO:0050789;cellular response to BMP stimulus#GO:0071773;transcription, DNA-templated#GO:0006351;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;response to BMP#GO:0071772;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;cellular developmental process#GO:0048869;positive regulation of transcription, DNA-templated#GO:0045893;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;BMP signaling pathway#GO:0030509;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;anatomical structure development#GO:0048856;transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0007178;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;response to growth factor#GO:0070848;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;positive regulation of biosynthetic process#GO:0009891;response to endogenous stimulus#GO:0009719;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of transcription by RNA polymerase II#GO:0000122;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;response to organic substance#GO:0010033;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular response to chemical stimulus#GO:0070887;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to growth factor stimulus#GO:0071363;negative regulation of macromolecule metabolic process#GO:0010605;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II transcription regulator complex#GO:0090575;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>SMAD1/5/8#P06787;Wnt signaling pathway#P00057>Smad4#P01455;Gonadotropin-releasing hormone receptor pathway#P06664>SMAD2-4#P06819;TGF-beta signaling pathway#P00052>RSmads#P01292 HUMAN|HGNC=12313|UniProtKB=Q15652 Q15652 JMJD1C PTHR12549:SF6 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 2C-RELATED nucleic acid binding#GO:0003676;demethylase activity#GO:0032451;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;catalytic activity, acting on a protein#GO:0140096 regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;demethylation#GO:0070988;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;protein demethylation#GO:0006482;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;histone deacetylase complex#GO:0000118;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=8259|UniProtKB=Q9GZK6 Q9GZK6 OR2J1 PTHR26453:SF184 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2J1 transmembrane signal receptor#PC00197 HUMAN|HGNC=15447|UniProtKB=Q9Y4G6 Q9Y4G6 TLN2 PTHR19981:SF34 TALIN TALIN-2 cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 anchoring junction#GO:0070161;focal adhesion#GO:0005925;cell junction#GO:0030054;cell-substrate junction#GO:0030055;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=17899|UniProtKB=Q9NYS0 Q9NYS0 NKIRAS1 PTHR46152:SF1 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN 1 HUMAN|HGNC=17948|UniProtKB=Q9Y2T7 Q9Y2T7 YBX2 PTHR11544:SF61 COLD SHOCK DOMAIN CONTAINING PROTEINS Y-BOX-BINDING PROTEIN 2 nucleic acid binding#GO:0003676;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;gene expression#GO:0010467;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=18944|UniProtKB=Q3LI61 Q3LI61 KRTAP20-2 PTHR39653:SF8 KERATIN-ASSOCIATED PROTEIN 20-2 KERATIN-ASSOCIATED PROTEIN 20-2 HUMAN|HGNC=15183|UniProtKB=Q8NH73 Q8NH73 OR4S2 PTHR48002:SF131 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 4S2 transmembrane signal receptor#PC00197 HUMAN|HGNC=33792|UniProtKB=A2A2V5 A2A2V5 SERTM1 PTHR35660:SF1 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 SERINE-RICH AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=28018|UniProtKB=Q0D2K0 Q0D2K0 NIPAL4 PTHR12570:SF7 UNCHARACTERIZED MAGNESIUM TRANSPORTER NIPA4 localization#GO:0051179;divalent metal ion transport#GO:0070838;metal ion transport#GO:0030001;establishment of localization#GO:0051234;ion transport#GO:0006811;transport#GO:0006810;divalent inorganic cation transport#GO:0072511;cation transport#GO:0006812 cellular anatomical entity#GO:0110165;membrane#GO:0016020 HUMAN|HGNC=24997|UniProtKB=A4D1P6 A4D1P6 WDR91 PTHR13083:SF3 UNCHARACTERIZED WD REPEAT-CONTAINING PROTEIN 91 transferase activity#GO:0016740;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;kinase activity#GO:0016301;kinase binding#GO:0019900 lipid metabolic process#GO:0006629;cellular localization#GO:0051641;regulation of phosphate metabolic process#GO:0019220;transport#GO:0006810;lipid modification#GO:0030258;phospholipid metabolic process#GO:0006644;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;glycerolipid metabolic process#GO:0046486;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;cellular metabolic process#GO:0044237;vesicle-mediated transport#GO:0016192;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;cellular process#GO:0009987;cytosolic transport#GO:0016482;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;organophosphate metabolic process#GO:0019637;regulation of lipid metabolic process#GO:0019216;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;phosphatidylinositol phosphorylation#GO:0046854;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;early endosome#GO:0005769;late endosome membrane#GO:0031902;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;late endosome#GO:0005770;plasma membrane#GO:0005886 HUMAN|HGNC=9457|UniProtKB=O94903 O94903 PLPBP PTHR10146:SF14 PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159 HUMAN|HGNC=1682|UniProtKB=Q08722 Q08722 CD47 PTHR10613:SF0 LEUKOCYTE SURFACE ANTIGEN CD47 LEUKOCYTE SURFACE ANTIGEN CD47 cell adhesion molecule#PC00069 HUMAN|HGNC=26317|UniProtKB=Q96LU5 Q96LU5 IMMP1L PTHR12383:SF33 PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1 cellular localization#GO:0051641;mitochondrial protein processing#GO:0034982;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;gene expression#GO:0010467;establishment of protein localization#GO:0045184;protein processing#GO:0016485;amide transport#GO:0042886;organic substance transport#GO:0071702;protein targeting to mitochondrion#GO:0006626;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;mitochondrion organization#GO:0007005;protein localization to organelle#GO:0033365;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein processing involved in protein targeting to mitochondrion#GO:0006627;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein targeting#GO:0006605;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;cellular metabolic process#GO:0044237;establishment of protein localization to organelle#GO:0072594;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;peptide transport#GO:0015833;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein localization#GO:0008104;localization#GO:0051179;mitochondrial transport#GO:0006839;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;organelle organization#GO:0006996;establishment of protein localization to mitochondrion#GO:0072655;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 mitochondrial protein complex#GO:0098798;envelope#GO:0031975;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 protease#PC00190 HUMAN|HGNC=6037|UniProtKB=Q12905 Q12905 ILF2 PTHR46447:SF1 INTERLEUKIN ENHANCER-BINDING FACTOR INTERLEUKIN ENHANCER-BINDING FACTOR 2 transcription cofactor#PC00217 HUMAN|HGNC=24500|UniProtKB=Q69YN4 Q69YN4 VIRMA PTHR23185:SF0 UNCHARACTERIZED PROTEIN VIRILIZER HOMOLOG HUMAN|HGNC=2259|UniProtKB=Q16206 Q16206 ENOX2 PTHR16001:SF7 ECTO-NOX DISULFIDE-THIOL EXCHANGER ECTO-NOX DISULFIDE-THIOL EXCHANGER 2 oxidoreductase#PC00176 HUMAN|HGNC=18832|UniProtKB=Q53GI3 Q53GI3 ZNF394 PTHR23226:SF3 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 394 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=4537|UniProtKB=Q9BPV8 Q9BPV8 P2RY13 PTHR24233:SF10 P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR P2Y PURINOCEPTOR 13 nucleotide binding#GO:0000166;signaling receptor activity#GO:0038023;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 G-protein coupled receptor#PC00021 HUMAN|HGNC=31849|UniProtKB=P23610 P23610 F8A1 PTHR16797:SF4 FACTOR VIII-ASSOCIATED GENE 1 40-KDA HUNTINGTIN-ASSOCIATED PROTEIN localization#GO:0051179;cellular localization#GO:0051641;organelle localization#GO:0051640;vesicle localization#GO:0051648;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of organelle localization#GO:0051656;vesicle cytoskeletal trafficking#GO:0099518 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;early endosome#GO:0005769;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 HUMAN|HGNC=25604|UniProtKB=Q8WVR3 Q8WVR3 MAP11 PTHR16096:SF8 MICROTUBULE-ASSOCIATED PROTEIN 11 MICROTUBULE-ASSOCIATED PROTEIN 11 HUMAN|HGNC=16277|UniProtKB=Q9C030 Q9C030 TRIM6 PTHR24103:SF51 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 6 transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;protein homodimerization activity#GO:0042803;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630;identical protein binding#GO:0042802;ubiquitin-like protein ligase activity#GO:0061659;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096;kinase binding#GO:0019900 regulation of catabolic process#GO:0009894;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of localization#GO:0032879;regulation of RNA biosynthetic process#GO:2001141;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;positive regulation of biological process#GO:0048518;regulation of protein localization#GO:0032880;organic substance metabolic process#GO:0071704;protein ubiquitination#GO:0016567;I-kappaB kinase/NF-kappaB signaling#GO:0007249;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;RNA biosynthetic process#GO:0032774;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;protein localization#GO:0008104;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of catabolic process#GO:0009896;aromatic compound biosynthetic process#GO:0019438;positive regulation of autophagy#GO:0010508;autophagy#GO:0006914;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular catabolic process#GO:0031331;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;protein modification process#GO:0036211;biosynthetic process#GO:0009058;process utilizing autophagic mechanism#GO:0061919;positive regulation of response to stimulus#GO:0048584;regulation of transcription, DNA-templated#GO:0006355;positive regulation of NF-kappaB transcription factor activity#GO:0051092;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;catabolic process#GO:0009056;positive regulation of intracellular signal transduction#GO:1902533;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;signaling#GO:0023052;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;regulation of DNA-binding transcription factor activity#GO:0051090;regulation of autophagy#GO:0010506;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-binding transcription factor activity#GO:0051091;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043122;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of I-kappaB kinase/NF-kappaB signaling#GO:0043123;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=3002|UniProtKB=P16444 P16444 DPEP1 PTHR10443:SF38 MICROSOMAL DIPEPTIDASE DIPEPTIDASE 1 protease#PC00190 HUMAN|HGNC=5210|UniProtKB=P14061 P14061 HSD17B1 PTHR43391:SF15 RETINOL DEHYDROGENASE-RELATED ESTRADIOL 17-BETA-DEHYDROGENASE 1 dehydrogenase#PC00092 Androgen/estrogene/progesterone biosynthesis#P02727>Estradiol 17beta-dehydrogenase#P02826 HUMAN|HGNC=24446|UniProtKB=Q96FZ2 Q96FZ2 HMCES PTHR13604:SF0 DC12-RELATED ABASIC SITE PROCESSING PROTEIN HMCES HUMAN|HGNC=14279|UniProtKB=Q6P1L8 Q6P1L8 MRPL14 PTHR21037:SF3 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 ribosomal protein#PC00202 HUMAN|HGNC=32979|UniProtKB=Q99871 Q99871 HAUS7 PTHR14352:SF2 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 cytoskeletal protein binding#GO:0008092;microtubule binding#GO:0008017;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049;spindle organization#GO:0007051 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=2485|UniProtKB=Q12996 Q12996 CSTF3 PTHR19980:SF0 RNA CLEAVAGE STIMULATION FACTOR CLEAVAGE STIMULATION FACTOR SUBUNIT 3 nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;RNA binding#GO:0003723;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=10540|UniProtKB=P21673 P21673 SAT1 PTHR10545:SF36 DIAMINE N-ACETYLTRANSFERASE DIAMINE ACETYLTRANSFERASE 1 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 acetyltransferase#PC00038 HUMAN|HGNC=28054|UniProtKB=Q5EBL2 Q5EBL2 ZNF628 PTHR24384:SF220 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 628 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=32423|UniProtKB=A6NNS2 A6NNS2 DHRS7C PTHR44668:SF2 FAMILY NOT NAMED DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7C HUMAN|HGNC=1487|UniProtKB=Q13938 Q13938 CAPS PTHR34524:SF2 CALCYPHOSIN CALCYPHOSIN membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982 calmodulin-related#PC00061 HUMAN|HGNC=26999|UniProtKB=Q6ZMY6 Q6ZMY6 WDR88 PTHR45048:SF1 FAMILY NOT NAMED WD REPEAT-CONTAINING PROTEIN 88 HUMAN|HGNC=1388|UniProtKB=O00555 O00555 CACNA1A PTHR45628:SF3 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT P/Q-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1A metal ion transport#GO:0030001;ion transport#GO:0006811;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cation transport#GO:0006812;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;divalent metal ion transport#GO:0070838;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;divalent inorganic cation transport#GO:0072511;cell-cell signaling#GO:0007267;signaling#GO:0023052 voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;GABA-B receptor II signaling#P05731>Ca channel#P05753;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 HUMAN|HGNC=30246|UniProtKB=Q9NP64 Q9NP64 ZCCHC17 PTHR15838:SF1 NUCLEOLAR PROTEIN OF 40 KDA NUCLEOLAR PROTEIN OF 40 KDA nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 posttranscriptional regulation of gene expression#GO:0010608;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;negative regulation of RNA metabolic process#GO:0051253;heterocycle catabolic process#GO:0046700;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;cellular nitrogen compound catabolic process#GO:0044270;regulation of biological process#GO:0050789;organic cyclic compound metabolic process#GO:1901360;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;organic substance catabolic process#GO:1901575;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;negative regulation of cellular catabolic process#GO:0031330;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;regulation of RNA stability#GO:0043487;cellular nitrogen compound metabolic process#GO:0034641;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;organic cyclic compound catabolic process#GO:1901361;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;cellular macromolecule catabolic process#GO:0044265;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 HUMAN|HGNC=20223|UniProtKB=Q9H8Y1 Q9H8Y1 VRTN PTHR16081:SF0 VERTNIN VERTNIN HUMAN|HGNC=2918|UniProtKB=P56178 P56178 DLX5 PTHR24327:SF31 HOMEOBOX PROTEIN HOMEOBOX PROTEIN DLX-5 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;anatomical structure formation involved in morphogenesis#GO:0048646;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;embryo development#GO:0009790;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=29873|UniProtKB=Q8N5F7 Q8N5F7 NKAP PTHR13087:SF2 NF-KAPPA B ACTIVATING PROTEIN NF-KAPPA-B-ACTIVATING PROTEIN chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of gene expression#GO:0010629;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;negative regulation of metabolic process#GO:0009892;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=19968|UniProtKB=Q96NT1 Q96NT1 NAP1L5 PTHR11875:SF36 TESTIS-SPECIFIC Y-ENCODED PROTEIN NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 2-RELATED protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;chromatin binding#GO:0003682 protein-DNA complex subunit organization#GO:0071824;cellular component assembly#GO:0022607;cellular developmental process#GO:0048869;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;chromatin assembly or disassembly#GO:0006333;nucleosome organization#GO:0034728;nucleosome assembly#GO:0006334;developmental process#GO:0032502;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;chromatin assembly#GO:0031497;protein-DNA complex assembly#GO:0065004;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell differentiation#GO:0030154;DNA conformation change#GO:0071103;DNA packaging#GO:0006323;organelle organization#GO:0006996;chromosome organization#GO:0051276;chromatin organization#GO:0006325;protein-containing complex subunit organization#GO:0043933 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 HUMAN|HGNC=22421|UniProtKB=Q9BRJ6 Q9BRJ6 C7orf50 PTHR22306:SF2 UNCHARACTERIZED CHROMOSOME 7 OPEN READING FRAME 50 HUMAN|HGNC=1067|UniProtKB=P13497 P13497 BMP1 PTHR10127:SF863 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING BONE MORPHOGENETIC PROTEIN 1 hydrolase activity#GO:0016787;metalloendopeptidase activity#GO:0004222;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metalloprotease#PC00153 TGF-beta signaling pathway#P00052>TGFbeta#P01286 HUMAN|HGNC=12557|UniProtKB=Q96PU4 Q96PU4 UHRF2 PTHR14140:SF3 E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED E3 UBIQUITIN-PROTEIN LIGASE UHRF2 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;heterochromatin#GO:0000792;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;nuclear heterochromatin#GO:0005720;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=16906|UniProtKB=Q9Y2Q3 Q9Y2Q3 GSTK1 PTHR42943:SF2 GLUTATHIONE S-TRANSFERASE KAPPA GLUTATHIONE S-TRANSFERASE KAPPA 1 transferase#PC00220 HUMAN|HGNC=24890|UniProtKB=Q9H1C3 Q9H1C3 GLT8D2 PTHR13778:SF2 GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN 2 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 glycosyltransferase#PC00111 HUMAN|HGNC=4696|UniProtKB=P08236 P08236 GUSB PTHR10066:SF67 BETA-GLUCURONIDASE BETA-GLUCURONIDASE-RELATED oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;organic acid catabolic process#GO:0016054;small molecule catabolic process#GO:0044282;cellular carbohydrate metabolic process#GO:0044262;cellular carbohydrate catabolic process#GO:0044275;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carbohydrate metabolic process#GO:0005975;carboxylic acid metabolic process#GO:0019752;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152 HUMAN|HGNC=4162|UniProtKB=P41250 P41250 GARS1 PTHR10745:SF0 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 GLYCINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;RNA metabolic process#GO:0016070;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translation#GO:0006412;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nucleic acid metabolic process#GO:0090304;cellular amino acid metabolic process#GO:0006520;translational elongation#GO:0006414;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 aminoacyl-tRNA synthetase#PC00047 HUMAN|HGNC=21707|UniProtKB=Q9BU79 Q9BU79 TMEM243 PTHR28603:SF1 TRANSMEMBRANE PROTEIN 243 TRANSMEMBRANE PROTEIN 243 HUMAN|HGNC=6355|UniProtKB=Q9C0H6 Q9C0H6 KLHL4 PTHR24412:SF74 KELCH PROTEIN KELCH-LIKE PROTEIN 4 scaffold/adaptor protein#PC00226 HUMAN|HGNC=8808|UniProtKB=P11177 P11177 PDHB PTHR11624:SF96 DEHYDROGENASE RELATED PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;acyl-CoA metabolic process#GO:0006637;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound biosynthetic process#GO:0034654;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleotide biosynthetic process#GO:0009152;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 dehydrogenase#PC00092 HUMAN|HGNC=33274|UniProtKB=A6NDB9 A6NDB9 PALM3 PTHR47528:SF1 PARALEMMIN-3 PARALEMMIN-3 HUMAN|HGNC=6632|UniProtKB=Q9HAT1 Q9HAT1 LMAN1L PTHR12223:SF31 VESICULAR MANNOSE-BINDING LECTIN PROTEIN ERGIC-53-LIKE carbohydrate binding#GO:0030246;small molecule binding#GO:0036094;binding#GO:0005488 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;endoplasmic reticulum organization#GO:0007029;Golgi organization#GO:0007030;transport#GO:0006810;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi apparatus#GO:0005794;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;coated vesicle#GO:0030135;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi-associated vesicle#GO:0005798;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;plasma membrane#GO:0005886;endoplasmic reticulum membrane#GO:0005789 membrane traffic protein#PC00150 HUMAN|HGNC=9606|UniProtKB=P01270 P01270 PTH PTHR10541:SF2 PARATHYROID HORMONE PARATHYROID HORMONE peptide hormone#PC00179 HUMAN|HGNC=30831|UniProtKB=Q8NHU6 Q8NHU6 TDRD7 PTHR22948:SF14 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 7 scaffold/adaptor protein#PC00226 HUMAN|HGNC=28419|UniProtKB=Q9BQ49 Q9BQ49 SMIM7 PTHR28622:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 7 SMALL INTEGRAL MEMBRANE PROTEIN 7 HUMAN|HGNC=19268|UniProtKB=Q8N2K1 Q8N2K1 UBE2J2 PTHR24068:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J2 ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;protein modification process#GO:0036211;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;protein polyubiquitination#GO:0000209;proteasomal protein catabolic process#GO:0010498;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein ubiquitination#GO:0016567;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular protein modification process#GO:0006464;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 cytoplasm#GO:0005737;nucleus#GO:0005634;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;membrane#GO:0016020;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Ubc6#P01222 HUMAN|HGNC=24588|UniProtKB=Q86XP6 Q86XP6 GKN2 PTHR16483:SF3 GASTROKINE 1 GASTROKINE-2 biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell population proliferation#GO:0008283;regulation of cell population proliferation#GO:0042127;regulation of cellular process#GO:0050794 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=6666|UniProtKB=Q9Y4K0 Q9Y4K0 LOXL2 PTHR45817:SF1 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE HOMOLOG 2 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 oxidase#PC00175 HUMAN|HGNC=24065|UniProtKB=Q9UH62 Q9UH62 ARMCX3 PTHR15712:SF8 ARMADILLO REPEAT CONTAINING PROTEIN ARMADILLO REPEAT-CONTAINING X-LINKED PROTEIN 3 HUMAN|HGNC=12897|UniProtKB=Q03924 Q03924 ZNF117 PTHR24384:SF120 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED ZINC FINGER PROTEIN 117 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 HUMAN|HGNC=18129|UniProtKB=Q9UBU3 Q9UBU3 GHRL PTHR14122:SF1 GHRELIN PRECURSOR APPETITE-REGULATING HORMONE peptide hormone#PC00179 HUMAN|HGNC=1084|UniProtKB=Q12983 Q12983 BNIP3 PTHR15186:SF4 RE48077P BCL2/ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3 signal transduction#GO:0007165;apoptotic mitochondrial changes#GO:0008637;membrane organization#GO:0061024;transport#GO:0006810;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;apoptotic process#GO:0006915;cell death#GO:0008219;mitochondrion organization#GO:0007005;regulation of membrane permeability#GO:0090559;positive regulation of biological process#GO:0048518;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;cell communication#GO:0007154;programmed cell death#GO:0012501;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;mitochondrial transport#GO:0006839;localization#GO:0051179;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;regulation of mitochondrial membrane permeability#GO:0046902;biological regulation#GO:0065007;regulation of cell death#GO:0010941;mitochondrial membrane organization#GO:0007006;positive regulation of cell death#GO:0010942 envelope#GO:0031975;bounding membrane of organelle#GO:0098588;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;intracellular#GO:0005622;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867 HUMAN|HGNC=24540|UniProtKB=Q9BS18 Q9BS18 ANAPC13 PTHR28672:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;protein polyubiquitination#GO:0000209;protein metabolic process#GO:0019538;protein K11-linked ubiquitination#GO:0070979;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;anaphase-promoting complex#GO:0005680;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular organelle#GO:0043229 HUMAN|HGNC=25570|UniProtKB=Q9NVH1 Q9NVH1 DNAJC11 PTHR44157:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;organelle organization#GO:0006996;cristae formation#GO:0042407;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;mitochondrion organization#GO:0007005;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;integral component of mitochondrial inner membrane#GO:0031305;mitochondrial membrane#GO:0031966;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;intrinsic component of mitochondrial inner membrane#GO:0031304;integral component of mitochondrial membrane#GO:0032592;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;integral component of membrane#GO:0016021;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;integral component of organelle membrane#GO:0031301;cytoplasm#GO:0005737;intrinsic component of organelle membrane#GO:0031300;protein-containing complex#GO:0032991;intrinsic component of membrane#GO:0031224;intrinsic component of mitochondrial membrane#GO:0098573;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;membrane-bounded organelle#GO:0043227 chaperone#PC00072 HUMAN|HGNC=16881|UniProtKB=Q7RTV5 Q7RTV5 PRXL2C PTHR28630:SF20 FAMILY NOT NAMED PEROXIREDOXIN-LIKE 2C oxidation-reduction process#GO:0055114;metabolic process#GO:0008152 HUMAN|HGNC=15661|UniProtKB=Q7RTX0 Q7RTX0 TAS1R3 PTHR24061:SF435 CALCIUM-SENSING RECEPTOR-RELATED TASTE RECEPTOR TYPE 1 MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;system process#GO:0003008 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=19344|UniProtKB=Q6IQ26 Q6IQ26 DENND5A PTHR46070:SF2 PINSTRIPE, ISOFORM A DENN DOMAIN-CONTAINING PROTEIN 5A HUMAN|HGNC=753|UniProtKB=P08243 P08243 ASNS PTHR11772:SF36 ASPARAGINE SYNTHETASE ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING] ligase activity#GO:0016874;catalytic activity#GO:0003824 organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular amino acid biosynthetic process#GO:0008652;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;aspartate family amino acid biosynthetic process#GO:0009067;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;alpha-amino acid metabolic process#GO:1901605;cellular amino acid metabolic process#GO:0006520;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ligase#PC00142 Asparagine and aspartate biosynthesis#P02730>Asparagine synthetase#P02853 HUMAN|HGNC=23189|UniProtKB=Q8TBB0 Q8TBB0 THAP6 PTHR47577:SF1 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN-CONTAINING PROTEIN 6 HUMAN|HGNC=29877|UniProtKB=Q14157 Q14157 UBAP2L PTHR16308:SF18 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER UBIQUITIN-ASSOCIATED PROTEIN 2-LIKE cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3053|UniProtKB=Q99645 Q99645 EPYC PTHR46269:SF3 EPIPHYCAN-RELATED EPIPHYCAN HUMAN|HGNC=18159|UniProtKB=Q9NNX9 Q9NNX9 VCX3A PTHR15251:SF2 TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED HUMAN|HGNC=9313|UniProtKB=Q16537 Q16537 PPP2R5E PTHR10257:SF80 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT EPSILON ISOFORM hydrolase activity, acting on ester bonds#GO:0016788;phosphatase binding#GO:0019902;phosphatase activity#GO:0016791;binding#GO:0005488;catalytic activity#GO:0003824;protein phosphatase regulator activity#GO:0019888;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;phosphoprotein phosphatase activity#GO:0004721;enzyme regulator activity#GO:0030234;phosphoric ester hydrolase activity#GO:0042578;phosphatase regulator activity#GO:0019208;hydrolase activity#GO:0016787;protein binding#GO:0005515;molecular function regulator#GO:0098772;protein phosphatase binding#GO:0019903;catalytic activity, acting on a protein#GO:0140096 regulation of protein modification process#GO:0031399;regulation of phosphate metabolic process#GO:0019220;regulation of protein metabolic process#GO:0051246;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of phosphorus metabolic process#GO:0051174;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;protein autophosphorylation#GO:0046777;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;regulation of protein kinase activity#GO:0045859;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein phosphorylation#GO:0001932;dephosphorylation#GO:0016311;biological regulation#GO:0065007;regulation of phosphorylation#GO:0042325;regulation of transferase activity#GO:0051338;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;protein serine/threonine phosphatase complex#GO:0008287;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 HUMAN|HGNC=25802|UniProtKB=Q8N4W6 Q8N4W6 DNAJC22 PTHR44733:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 chaperone#PC00072 HUMAN|HGNC=6378|UniProtKB=Q13241 Q13241 KLRD1 PTHR22800:SF246 C-TYPE LECTIN PROTEINS NATURAL KILLER CELLS ANTIGEN CD94 HUMAN|HGNC=24968|UniProtKB=Q96KP1 Q96KP1 EXOC2 PTHR13043:SF1 EXOCYST COMPLEX COMPONENT SEC5 EXOCYST COMPLEX COMPONENT 2 vesicle fusion#GO:0006906;vesicle-mediated transport to the plasma membrane#GO:0098876;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;post-Golgi vesicle-mediated transport#GO:0006892;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;exocytic process#GO:0140029;Golgi to plasma membrane transport#GO:0006893;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;organelle organization#GO:0006996;secretion#GO:0046903;vesicle organization#GO:0016050;export from cell#GO:0140352;secretion by cell#GO:0032940;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165 Ras Pathway#P04393>Sec5#P04545 HUMAN|HGNC=5004|UniProtKB=O15347 O15347 HMGB3 PTHR48112:SF14 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B3 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;DNA binding, bending#GO:0008301;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=1705|UniProtKB=P42081 P42081 CD86 PTHR25466:SF2 T-LYMPHOCYTE ACTIVATION ANTIGEN T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 response to external biotic stimulus#GO:0043207;regulation of cell-cell adhesion#GO:0022407;positive regulation of cell population proliferation#GO:0008284;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;response to biotic stimulus#GO:0009607;leukocyte proliferation#GO:0070661;regulation of leukocyte cell-cell adhesion#GO:1903037;negative regulation of leukocyte cell-cell adhesion#GO:1903038;response to molecule of bacterial origin#GO:0002237;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;mononuclear cell proliferation#GO:0032943;negative regulation of T cell proliferation#GO:0042130;response to oxygen-containing compound#GO:1901700;negative regulation of T cell activation#GO:0050868;cellular response to organic substance#GO:0071310;interspecies interaction between organisms#GO:0044419;cellular response to biotic stimulus#GO:0071216;cell communication#GO:0007154;cell adhesion#GO:0007155;response to lipopolysaccharide#GO:0032496;negative regulation of leukocyte activation#GO:0002695;negative regulation of cell adhesion#GO:0007162;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to lipopolysaccharide#GO:0071222;negative regulation of cell-cell adhesion#GO:0022408;biological adhesion#GO:0022610;response to lipid#GO:0033993;positive regulation of T cell proliferation#GO:0042102;cellular response to lipid#GO:0071396;leukocyte cell-cell adhesion#GO:0007159;T cell proliferation#GO:0042098;cellular response to oxygen-containing compound#GO:1901701;response to bacterium#GO:0009617;positive regulation of leukocyte cell-cell adhesion#GO:1903039;negative regulation of cell population proliferation#GO:0008285;regulation of immune system process#GO:0002682;regulation of cell adhesion#GO:0030155;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;response to organic substance#GO:0010033;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;negative regulation of cell activation#GO:0050866;regulation of T cell proliferation#GO:0042129;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;regulation of mononuclear cell proliferation#GO:0032944;T cell activation#GO:0042110;response to chemical#GO:0042221;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;negative regulation of immune system process#GO:0002683;regulation of leukocyte proliferation#GO:0070663;negative regulation of lymphocyte activation#GO:0051250;positive regulation of cell adhesion#GO:0045785;positive regulation of cell-cell adhesion#GO:0022409 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin receptor superfamily#PC00124 T cell activation#P00053>B7#P01337 HUMAN|HGNC=13703|UniProtKB=Q9BXY0 Q9BXY0 MAK16 PTHR23405:SF4 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED PROTEIN MAK16 HOMOLOG cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;preribosome, large subunit precursor#GO:0030687;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981 HUMAN|HGNC=29186|UniProtKB=Q9UPS8 Q9UPS8 ANKRD26 PTHR24147:SF57 ANKYRIN REPEAT DOMAIN 36-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 26-RELATED HUMAN|HGNC=3497|UniProtKB=P57679 P57679 EVC PTHR16795:SF13 LIMBIN/ELLIS-VAN CREVELD PROTEIN ELLIS-VAN CREVELD SYNDROME PROTEIN HUMAN|HGNC=1569|UniProtKB=P06307 P06307 CCK PTHR10786:SF0 CHOLECYSTOKININ CHOLECYSTOKININ neuropeptide hormone activity#GO:0005184;binding#GO:0005488;receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;hormone activity#GO:0005179;signaling receptor binding#GO:0005102 multicellular organismal process#GO:0032501;digestion#GO:0007586 neuron projection#GO:0043005;extracellular region#GO:0005576;plasma membrane region#GO:0098590;cell projection#GO:0042995;extracellular space#GO:0005615;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;plasma membrane#GO:0005886;axon#GO:0030424 CCKR signaling map#P06959>Pro CCK @ TGN#P07174;CCKR signaling map#P06959>CCK-83#P07118;CCKR signaling map#P06959>CCK-58#P07164;CCKR signaling map#P06959>CCK-GRR#P07131;CCKR signaling map#P06959>Pre-pro CCK @ ER#P07128;CCKR signaling map#P06959>CCK-8#P07226;CCKR signaling map#P06959>CCK-33#P07045;CCKR signaling map#P06959>CCK#P07077;CCKR signaling map#P06959>CCK-22#P07022;CCKR signaling map#P06959>Signal-pre-pro CCK#P07223;CCKR signaling map#P06959>CCK-G#P07062;CCKR signaling map#P06959>Pro-CCK @ secretory granule#P07206 HUMAN|HGNC=7666|UniProtKB=Q9Y2A7 Q9Y2A7 NCKAP1 PTHR12093:SF11 NCK-ASSOCIATED PROTEIN 1 NCK-ASSOCIATED PROTEIN 1 Ras GTPase binding#GO:0017016;binding#GO:0005488;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;protein binding#GO:0005515;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048 cellular component biogenesis#GO:0044085;neurogenesis#GO:0022008;cell projection organization#GO:0030030;developmental process#GO:0032502;cell projection morphogenesis#GO:0048858;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;system development#GO:0048731;cell differentiation#GO:0030154;actin filament-based process#GO:0030029;anatomical structure morphogenesis#GO:0009653;neuron differentiation#GO:0030182;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;multicellular organism development#GO:0007275;localization of cell#GO:0051674;cellular component organization#GO:0016043;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell projection assembly#GO:0030031;localization#GO:0051179;cell development#GO:0048468;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;organelle organization#GO:0006996;anatomical structure development#GO:0048856;cortical cytoskeleton organization#GO:0030865;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;generation of neurons#GO:0048699;cell migration#GO:0016477;locomotion#GO:0040011;cortical actin cytoskeleton organization#GO:0030866 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622 HUMAN|HGNC=39004|UniProtKB=P10266 P10266 ERVK-10 PTHR41694:SF4 ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN ENDOGENOUS RETROVIRUS GROUP K MEMBER 10 POL PROTEIN-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 viral or transposable element protein#PC00237 HUMAN|HGNC=1389|UniProtKB=Q00975 Q00975 CACNA1B PTHR45628:SF6 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT N-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1B metal ion transport#GO:0030001;ion transport#GO:0006811;transport#GO:0006810;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cation transport#GO:0006812;cellular process#GO:0009987;calcium ion transport#GO:0006816;localization#GO:0051179;divalent metal ion transport#GO:0070838;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;divalent inorganic cation transport#GO:0072511;cell-cell signaling#GO:0007267;signaling#GO:0023052 voltage-gated ion channel#PC00241 Ionotropic glutamate receptor pathway#P00037>Ca2+ channel#P01022;Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587;Endogenous cannabinoid signaling#P05730>Ca2+ channel#P05750;Metabotropic glutamate receptor group II pathway#P00040>Ca2+#P01051;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Ca2+channel#P00742;GABA-B receptor II signaling#P05731>Ca channel#P05753;Metabotropic glutamate receptor group III pathway#P00039>Ca2+#P01041 HUMAN|HGNC=5000|UniProtKB=P26583 P26583 HMGB2 PTHR48112:SF3 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN B2 heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;DNA binding, bending#GO:0008301;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=13013|UniProtKB=Q92794 Q92794 KAT6A PTHR10615:SF26 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT6A protein binding#GO:0005515;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;molecular function regulator#GO:0098772;histone binding#GO:0042393;binding#GO:0005488 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;histone modification#GO:0016570;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;protein acylation#GO:0043543;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of transcription, DNA-templated#GO:0045892;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;protein acetylation#GO:0006473;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;internal protein amino acid acetylation#GO:0006475;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;histone H3 acetylation#GO:0043966;positive regulation of nitrogen compound metabolic process#GO:0051173;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;peptidyl-lysine acetylation#GO:0018394;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;histone acetylation#GO:0016573;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;covalent chromatin modification#GO:0016569;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;internal peptidyl-lysine acetylation#GO:0018393;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle organization#GO:0006996;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;histone acetyltransferase complex#GO:0000123;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;acetyltransferase complex#GO:1902493;catalytic complex#GO:1902494;chromatin#GO:0000785;nucleoplasm#GO:0005654;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;nuclear chromatin#GO:0000790;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome#GO:0005694;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 histone modifying enzyme#PC00261 HUMAN|HGNC=4167|UniProtKB=O43903 O43903 GAS2 PTHR46756:SF9 TRANSGELIN GROWTH ARREST-SPECIFIC PROTEIN 2 cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090;tubulin binding#GO:0015631;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;actin filament binding#GO:0051015;protein binding#GO:0005515;microtubule binding#GO:0008017;protein-containing complex binding#GO:0044877;actin binding#GO:0003779 cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;microtubule-based process#GO:0007017;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;actin filament#GO:0005884;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 HUMAN|HGNC=21574|UniProtKB=Q8N6K7 Q8N6K7 SAMD3 PTHR47302:SF1 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 3 STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=3978|UniProtKB=O75891 O75891 ALDH1L1 PTHR11699:SF120 ALDEHYDE DEHYDROGENASE-RELATED CYTOSOLIC 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 HUMAN|HGNC=24845|UniProtKB=Q9BXF6 Q9BXF6 RAB11FIP5 PTHR15746:SF14 RAB11-RELATED RAB11 FAMILY-INTERACTING PROTEIN 5 GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;Ras GTPase binding#GO:0017016;small GTPase binding#GO:0031267;binding#GO:0005488;Rab GTPase binding#GO:0017137 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;localization#GO:0051179;regulated exocytosis#GO:0045055;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;organelle organization#GO:0006996;vesicle organization#GO:0016050;export from cell#GO:0140352;vesicle fusion to plasma membrane#GO:0099500;organelle fusion#GO:0048284;secretion by cell#GO:0032940 endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;early endosome#GO:0005769;vacuole#GO:0005773;mitochondrion#GO:0005739;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=30534|UniProtKB=Q5VTE6 Q5VTE6 ANGEL2 PTHR12121:SF27 CARBON CATABOLITE REPRESSOR PROTEIN 4 PROTEIN ANGEL HOMOLOG 2 hydrolase activity, acting on ester bonds#GO:0016788;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;3'-5'-exoribonuclease activity#GO:0000175;binding#GO:0005488;catalytic activity#GO:0003824;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters#GO:0016796;exonuclease activity#GO:0004527;mRNA 3'-UTR binding#GO:0003730;catalytic activity, acting on RNA#GO:0140098;RNA binding#GO:0003723;organic cyclic compound binding#GO:0097159;hydrolase activity#GO:0016787;ribonuclease activity#GO:0004540;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;3'-5' exonuclease activity#GO:0008408 negative regulation of gene expression#GO:0010629;positive regulation of gene expression#GO:0010628;posttranscriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;heterocycle catabolic process#GO:0046700;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;organic substance metabolic process#GO:0071704;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;cellular nitrogen compound catabolic process#GO:0044270;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;mRNA catabolic process#GO:0006402;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;regulation of gene expression#GO:0010468;organic substance catabolic process#GO:1901575;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;heterocycle metabolic process#GO:0046483;negative regulation of cellular catabolic process#GO:0031330;regulation of cellular catabolic process#GO:0031329;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;aromatic compound catabolic process#GO:0019439;negative regulation of catabolic process#GO:0009895;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;organic cyclic compound catabolic process#GO:1901361;biological regulation#GO:0065007;cellular macromolecule catabolic process#GO:0044265 mRNA polyadenylation factor#PC00146 HUMAN|HGNC=18248|UniProtKB=Q6IA86 Q6IA86 ELP2 PTHR44111:SF1 ELONGATOR COMPLEX PROTEIN 2 ELONGATOR COMPLEX PROTEIN 2 HUMAN|HGNC=9868|UniProtKB=Q99969 Q99969 RARRES2 PTHR15106:SF2 RETINOIC ACID RECEPTOR RESPONDER PROTEIN 2 RETINOIC ACID RECEPTOR RESPONDER PROTEIN 2 HUMAN|HGNC=12828|UniProtKB=P18887 P18887 XRCC1 PTHR11370:SF5 DNA-REPAIR PROTEIN XRCC1 DNA REPAIR PROTEIN XRCC1 DNA metabolism protein#PC00009 HUMAN|HGNC=28326|UniProtKB=Q6UX07 Q6UX07 DHRS13 PTHR43157:SF44 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 13 glycosyltransferase#PC00111 HUMAN|HGNC=3655|UniProtKB=P16591 P16591 FER PTHR24418:SF227 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FER protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein binding#GO:0005515;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;kinase activity#GO:0016301;protein kinase activity#GO:0004672 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;cellular localization#GO:0051641;organelle localization#GO:0051640;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;regulation of vesicle-mediated transport#GO:0060627;lysosome localization#GO:0032418;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulated exocytosis#GO:0045055;response to biotic stimulus#GO:0009607;peptidyl-tyrosine phosphorylation#GO:0018108;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;regulation of secretion#GO:0051046;secretion#GO:0046903;innate immune response#GO:0045087;positive regulation of immune effector process#GO:0002699;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;leukocyte activation#GO:0045321;regulation of exocytosis#GO:0017157;organic substance metabolic process#GO:0071704;organelle fusion#GO:0048284;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular developmental process#GO:0048869;immune response-regulating cell surface receptor signaling pathway#GO:0002768;enzyme linked receptor protein signaling pathway#GO:0007167;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of cellular localization#GO:0060341;cell activation involved in immune response#GO:0002263;exocytic process#GO:0140029;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;leukocyte activation involved in immune response#GO:0002366;exocytosis#GO:0006887;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;locomotion#GO:0040011;export from cell#GO:0140352;taxis#GO:0042330;vesicle fusion#GO:0006906;signal transduction#GO:0007165;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;biological adhesion#GO:0022610;transport#GO:0006810;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;cell differentiation#GO:0030154;regulation of transport#GO:0051049;protein autophosphorylation#GO:0046777;vesicle organization#GO:0016050;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;protein metabolic process#GO:0019538;immune effector process#GO:0002252;signaling#GO:0023052;chemotaxis#GO:0006935;secretion by cell#GO:0032940;metabolic process#GO:0008152;vesicle fusion to plasma membrane#GO:0099500;cellular response to stimulus#GO:0051716;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;positive regulation of immune system process#GO:0002684;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;response to stimulus#GO:0050896;regulation of immune effector process#GO:0002697;response to external stimulus#GO:0009605;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;membrane fusion#GO:0061025;peptidyl-tyrosine modification#GO:0018212;response to chemical#GO:0042221;response to other organism#GO:0051707;organelle organization#GO:0006996;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of leukocyte mediated immunity#GO:0002703;establishment of localization in cell#GO:0051649 extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;leaflet of membrane bilayer#GO:0097478;intracellular#GO:0005622;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;plasma membrane#GO:0005886;extrinsic component of membrane#GO:0019898 Cadherin signaling pathway#P00012>Fer#P00469 HUMAN|HGNC=20250|UniProtKB=Q96IF1 Q96IF1 AJUBA PTHR24219:SF7 LIM DOMAIN-CONTAINING PROTEIN JUB LIM DOMAIN-CONTAINING PROTEIN AJUBA molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 negative regulation of gene expression#GO:0010629;posttranscriptional regulation of gene expression#GO:0010608;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;post-transcriptional gene silencing by RNA#GO:0035194;regulation of intracellular signal transduction#GO:1902531;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;gene silencing#GO:0016458;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;regulation of gene expression, epigenetic#GO:0040029;organic substance metabolic process#GO:0071704;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;response to decreased oxygen levels#GO:0036293;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cell communication#GO:0007154;cellular nitrogen compound metabolic process#GO:0034641;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;posttranscriptional gene silencing#GO:0016441;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of signal transduction#GO:0009968;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to hypoxia#GO:0001666;RNA metabolic process#GO:0016070;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of gene silencing#GO:0060968;metabolic process#GO:0008152;response to oxygen levels#GO:0070482;nucleic acid-templated transcription#GO:0097659;regulation of cell communication#GO:0010646;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;gene silencing by miRNA#GO:0035195;macromolecule biosynthetic process#GO:0009059;negative regulation of response to stimulus#GO:0048585;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;gene silencing by RNA#GO:0031047;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;hippo signaling#GO:0035329;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 supramolecular complex#GO:0099080;nucleus#GO:0005634;P-body#GO:0000932;intracellular membrane-bounded organelle#GO:0043231;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912 transcription cofactor#PC00217 HUMAN|HGNC=24555|UniProtKB=Q8N201 Q8N201 INTS1 PTHR21224:SF1 UNCHARACTERIZED INTEGRATOR COMPLEX SUBUNIT 1 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;RNA 3'-end processing#GO:0031123;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;snRNA 3'-end processing#GO:0034472;snRNA processing#GO:0016180;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;integrator complex#GO:0032039 HUMAN|HGNC=30829|UniProtKB=Q9BVA1 Q9BVA1 TUBB2B PTHR11588:SF330 TUBULIN TUBULIN BETA-2B CHAIN carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;structural molecule activity#GO:0005198;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;nuclear division#GO:0000280;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;localization of cell#GO:0051674;cell motility#GO:0048870;cellular component organization#GO:0016043;nervous system development#GO:0007399;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;system development#GO:0048731;cell differentiation#GO:0030154;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;organelle organization#GO:0006996;anatomical structure development#GO:0048856;neuron migration#GO:0001764;movement of cell or subcellular component#GO:0006928;cell cycle#GO:0007049;multicellular organismal process#GO:0032501;mitotic nuclear division#GO:0140014;organelle fission#GO:0048285;cytoskeleton organization#GO:0007010;generation of neurons#GO:0048699;cell migration#GO:0016477;locomotion#GO:0040011 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 tubulin#PC00228 Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790;Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526 HUMAN|HGNC=8005|UniProtKB=O60462 O60462 NRP2 PTHR46806:SF2 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN NEUROPILIN-2 HUMAN|HGNC=5576|UniProtKB=P01817 P01817 IGHV2-5 PTHR23266:SF259 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 2-5 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=21294|UniProtKB=Q14681 Q14681 KCTD2 PTHR14958:SF22 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD2 protein binding#GO:0005515;binding#GO:0005488 macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;modification-dependent macromolecule catabolic process#GO:0043632;cellular protein catabolic process#GO:0044257;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;cellular protein metabolic process#GO:0044267;proteolysis involved in cellular protein catabolic process#GO:0051603;protein metabolic process#GO:0019538;cellular macromolecule catabolic process#GO:0044265;cellular catabolic process#GO:0044248;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 HUMAN|HGNC=30531|UniProtKB=Q96A22 Q96A22 C11orf52 PTHR37342:SF1 HYPOTHETICAL PROTEIN LOC689959 HYPOTHETICAL PROTEIN LOC689959 membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;extracellular region#GO:0005576 HUMAN|HGNC=19616|UniProtKB=A6NL26 A6NL26 OR5B21 PTHR48018:SF8 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5B21 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=17829|UniProtKB=Q9NPR9 Q9NPR9 GPR108 PTHR21229:SF11 LUNG SEVEN TRANSMEMBRANE RECEPTOR PROTEIN GPR108 localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;organelle#GO:0043226;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=9325|UniProtKB=P50897 P50897 PPT1 PTHR11247:SF8 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 PALMITOYL-PROTEIN THIOESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790 cytoplasm#GO:0005737;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 HUMAN|HGNC=32005|UniProtKB=Q5VU36 Q5VU36 SPATA31A5 PTHR21859:SF55 ACROSOME-SPECIFIC PROTEIN SPERMATOGENESIS-ASSOCIATED PROTEIN 31A1-RELATED HUMAN|HGNC=19295|UniProtKB=Q96Q04 Q96Q04 LMTK3 PTHR24417:SF2 SERINE/THREONINE-PROTEIN KINASE LMTK1 SERINE/THREONINE-PROTEIN KINASE LMTK3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;phosphorylation#GO:0016310;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=26036|UniProtKB=Q9NX08 Q9NX08 COMMD8 PTHR16231:SF0 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 8 HUMAN|HGNC=26027|UniProtKB=Q9H0A8 Q9H0A8 COMMD4 PTHR16231:SF11 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 4 HUMAN|HGNC=6945|UniProtKB=P25205 P25205 MCM3 PTHR11630:SF46 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM3 sequence-specific double-stranded DNA binding#GO:1990837;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;double-stranded DNA binding#GO:0003690 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;double-strand break repair#GO:0006302;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;recombinational repair#GO:0000725;mitotic nuclear division#GO:0140014;protein-containing complex subunit organization#GO:0043933;cell cycle DNA replication#GO:0044786;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;nuclear DNA replication#GO:0033260;protein-DNA complex subunit organization#GO:0071824;cellular macromolecule biosynthetic process#GO:0034645;cellular protein-containing complex assembly#GO:0034622;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;pre-replicative complex assembly involved in nuclear cell cycle DNA replication#GO:0006267;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;DNA-dependent DNA replication#GO:0006261;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;double-strand break repair via homologous recombination#GO:0000724;organic cyclic compound biosynthetic process#GO:1901362;DNA recombination#GO:0006310;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;organelle organization#GO:0006996;DNA biosynthetic process#GO:0071897;mitotic DNA replication#GO:1902969;cell cycle#GO:0007049;aromatic compound biosynthetic process#GO:0019438;organelle fission#GO:0048285;cellular response to stress#GO:0033554;DNA replication#GO:0006260;DNA replication initiation#GO:0006270;DNA strand elongation involved in DNA replication#GO:0006271;DNA metabolic process#GO:0006259 protein-containing complex#GO:0032991;nucleus#GO:0005634;MCM core complex#GO:0097373;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=28139|UniProtKB=Q9BT56 Q9BT56 SPX PTHR28590:SF1 SPEXIN SPEXIN HUMAN|HGNC=2091|UniProtKB=P09497 P09497 CLTB PTHR10639:SF28 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN B protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;membrane organization#GO:0061024;clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;transport#GO:0006810;protein-containing complex assembly#GO:0065003;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;establishment of localization#GO:0051234;membrane invagination#GO:0010324;organelle organization#GO:0006996;vesicle organization#GO:0016050;receptor-mediated endocytosis#GO:0006898;protein-containing complex subunit organization#GO:0043933 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vacuole#GO:0005773;clathrin vesicle coat#GO:0030125;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;clathrin-coated vesicle#GO:0030136;membrane coat#GO:0030117;intracellular#GO:0005622;postsynapse#GO:0098794;coated membrane#GO:0048475;cytoplasmic vesicle membrane#GO:0030659;synaptic vesicle membrane#GO:0030672;presynapse#GO:0098793;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cell junction#GO:0030054;cytoplasmic region#GO:0099568;cell cortex#GO:0005938;cell periphery#GO:0071944;membrane#GO:0016020;coated vesicle#GO:0030135;vesicle coat#GO:0030120;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;exocytic vesicle#GO:0070382;endomembrane system#GO:0012505;coated vesicle membrane#GO:0030662;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;transport vesicle#GO:0030133;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 vesicle coat protein#PC00235 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722;Huntington disease#P00029>Clathrin#P00798 HUMAN|HGNC=32522|UniProtKB=A6NI72 A6NI72 NCF1B PTHR15706:SF6 SH3 MULTIPLE DOMAIN NEUTROPHIL CYTOSOL FACTOR 1-RELATED phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;catalytic activity#GO:0003824;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152 HUMAN|HGNC=14539|UniProtKB=Q63HN8 Q63HN8 RNF213 PTHR22605:SF16 UNCHARACTERIZED E3 UBIQUITIN-PROTEIN LIGASE RNF213 HUMAN|HGNC=8022|UniProtKB=P49902 P49902 NT5C2 PTHR12103:SF17 5'-NUCLEOTIDASE DOMAIN-CONTAINING CYTOSOLIC PURINE 5'-NUCLEOTIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;phosphoric ester hydrolase activity#GO:0042578 nucleotide phosphatase#PC00173 HUMAN|HGNC=24626|UniProtKB=O95881 O95881 TXNDC12 PTHR15337:SF10 ANTERIOR GRADIENT PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 12 regulation of biological process#GO:0050789;negative regulation of cell death#GO:0060548;negative regulation of biological process#GO:0048519;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell death#GO:0010941;cell death#GO:0008219;cellular process#GO:0009987;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 reductase#PC00198 HUMAN|HGNC=33741|UniProtKB=Q6ZTZ1 Q6ZTZ1 MSANTD1 PTHR22666:SF3 UNCHARACTERIZED MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 positive regulation of gene expression#GO:0010628;cellular aromatic compound metabolic process#GO:0006725;positive regulation of nitrogen compound metabolic process#GO:0051173;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;positive regulation of biosynthetic process#GO:0009891;transcription, DNA-templated#GO:0006351;positive regulation of metabolic process#GO:0009893;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;positive regulation of cellular biosynthetic process#GO:0031328;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of nucleic acid-templated transcription#GO:1903508;positive regulation of RNA metabolic process#GO:0051254;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 HUMAN|HGNC=3046|UniProtKB=P57054 P57054 PIGP PTHR46346:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P transferase#PC00220 HUMAN|HGNC=6332|UniProtKB=Q99706 Q99706 KIR2DL4 PTHR11738:SF158 MHC CLASS I NK CELL RECEPTOR KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 2DL4 immunoglobulin receptor superfamily#PC00124 HUMAN|HGNC=24944|UniProtKB=Q9NX09 Q9NX09 DDIT4 PTHR12478:SF7 DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4 DNA DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN protein binding#GO:0005515;binding#GO:0005488 signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;response to hypoxia#GO:0001666;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of TOR signaling#GO:0032007;regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;apoptotic process#GO:0006915;cell death#GO:0008219;intracellular signal transduction#GO:0035556;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;TOR signaling#GO:0031929;response to oxygen levels#GO:0070482;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;response to decreased oxygen levels#GO:0036293;cell communication#GO:0007154;programmed cell death#GO:0012501;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;response to stress#GO:0006950;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968 HUMAN|HGNC=30141|UniProtKB=Q96Q83 Q96Q83 ALKBH3 PTHR31212:SF4 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=28883|UniProtKB=Q9H2U2 Q9H2U2 PPA2 PTHR10286:SF49 INORGANIC PYROPHOSPHATASE INORGANIC PYROPHOSPHATASE 2, MITOCHONDRIAL pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824 cellular metabolic process#GO:0044237;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;extracellular space#GO:0005615;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular organelle#GO:0043229 pyrophosphatase#PC00196 HUMAN|HGNC=29399|UniProtKB=Q96PX9 Q96PX9 PLEKHG4B PTHR45845:SF1 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 4B guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=2397|UniProtKB=P53674 P53674 CRYBB1 PTHR11818:SF12 BETA/GAMMA CRYSTALLIN BETA-CRYSTALLIN B1 structural molecule activity#GO:0005198 system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;eye development#GO:0001654;system process#GO:0003008;developmental process#GO:0032502;multicellular organismal process#GO:0032501;lens development in camera-type eye#GO:0002088;camera-type eye development#GO:0043010;sensory perception#GO:0007600;nervous system process#GO:0050877;visual system development#GO:0150063;sensory system development#GO:0048880;sensory organ development#GO:0007423 HUMAN|HGNC=9323|UniProtKB=O00743 O00743 PPP6C PTHR45619:SF10 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE/THREONINE-PROTEIN PHOSPHATASE 6 CATALYTIC SUBUNIT protein phosphatase#PC00195 EGF receptor signaling pathway#P00018>PP2A#P00547;FGF signaling pathway#P00021>PP2A#P00629 HUMAN|HGNC=25229|UniProtKB=Q9NU23 Q9NU23 LYRM2 PTHR13675:SF3 LYR MOTIF-CONTAINING PROTEIN 2 LYR MOTIF-CONTAINING PROTEIN 2 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=3682|UniProtKB=P08620 P08620 FGF4 PTHR11486:SF31 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR 4 receptor regulator activity#GO:0030545;binding#GO:0005488;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;growth factor receptor binding#GO:0070851;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102;fibroblast growth factor receptor binding#GO:0005104 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;regulation of localization#GO:0032879;cell population proliferation#GO:0008283;positive regulation of protein modification process#GO:0031401;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;regulation of cell migration#GO:0030334;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;transmembrane receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cellular component movement#GO:0051270;cellular developmental process#GO:0048869;cellular response to endogenous stimulus#GO:0071495;cellular response to organic substance#GO:0071310;macromolecule metabolic process#GO:0043170;enzyme linked receptor protein signaling pathway#GO:0007167;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;localization of cell#GO:0051674;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;multicellular organismal process#GO:0032501;locomotion#GO:0040011;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;regulation of locomotion#GO:0040012;macromolecule modification#GO:0043412;response to growth factor#GO:0070848;animal organ development#GO:0048513;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;protein modification process#GO:0036211;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;response to organic substance#GO:0010033;positive regulation of protein phosphorylation#GO:0001934;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;cellular response to chemical stimulus#GO:0070887;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;cell motility#GO:0048870;protein phosphorylation#GO:0006468;cellular process#GO:0009987;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;response to chemical#GO:0042221;regulation of macromolecule metabolic process#GO:0060255;cellular response to growth factor stimulus#GO:0071363;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;animal organ morphogenesis#GO:0009887;positive regulation of cellular protein metabolic process#GO:0032270;cell migration#GO:0016477 cytoplasm#GO:0005737;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576;intracellular#GO:0005622 growth factor#PC00112 FGF signaling pathway#P00021>FGF#P00623 HUMAN|HGNC=14377|UniProtKB=Q9NX24 Q9NX24 NHP2 PTHR23105:SF129 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER H/ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 2 snoRNA binding#GO:0030515;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;RNA phosphodiester bond hydrolysis#GO:0090501;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cleavage involved in rRNA processing#GO:0000469;heterocycle metabolic process#GO:0046483;snRNA metabolic process#GO:0016073;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;nucleic acid phosphodiester bond hydrolysis#GO:0090305;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of LSU-rRNA#GO:0000470 small nucleolar ribonucleoprotein complex#GO:0005732;membrane-enclosed lumen#GO:0031974;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;cytosolic large ribosomal subunit#GO:0022625;intracellular#GO:0005622;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;ribosome#GO:0005840 ribosomal protein#PC00202 HUMAN|HGNC=1293|UniProtKB=P58511 P58511 SMIM11A PTHR35975:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 11A SMALL INTEGRAL MEMBRANE PROTEIN 11A HUMAN|HGNC=28918|UniProtKB=Q8WUY8 Q8WUY8 NAT14 PTHR13947:SF37 GNAT FAMILY N-ACETYLTRANSFERASE N-ACETYLTRANSFERASE 14 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;N-acyltransferase activity#GO:0016410 acetyltransferase#PC00038 HUMAN|HGNC=16631|UniProtKB=P82909 P82909 MRPS36 PTHR31601:SF3 28S RIBOSOMAL PROTEIN S36, MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S36, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;cellular metabolic process#GO:0044237;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;organic acid metabolic process#GO:0006082;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;mitochondrial protein complex#GO:0098798;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle lumen#GO:0070013;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 HUMAN|HGNC=28640|UniProtKB=Q53RE8 Q53RE8 ANKRD39 PTHR24171:SF8 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED HUMAN|HGNC=29298|UniProtKB=O94986 O94986 CEP152 PTHR10337:SF6 SHC TRANSFORMING PROTEIN CENTROSOMAL PROTEIN OF 152 KDA enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;centrosome cycle#GO:0007098;centrosome duplication#GO:0051298;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule organizing center organization#GO:0031023;centriole replication#GO:0007099;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cell cycle#GO:0007049 intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule organizing center#GO:0005815;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;centriole#GO:0005814;organelle#GO:0043226;intracellular organelle#GO:0043229;centrosome#GO:0005813 scaffold/adaptor protein#PC00226 HUMAN|HGNC=31690|UniProtKB=Q8TCD1 Q8TCD1 C18orf32 PTHR13456:SF0 UPF0729 PROTEIN C18ORF32 UPF0729 PROTEIN C18ORF32 HUMAN|HGNC=33769|UniProtKB=P0C671 P0C671 BNIP5 PTHR22435:SF0 CHROMOSOME 6 OPEN READING FRAME 222 PROTEIN BNIP5 HUMAN|HGNC=30207|UniProtKB=Q52LW3 Q52LW3 ARHGAP29 PTHR15228:SF7 SPERMATHECAL PHYSIOLOGY VARIANT RHO GTPASE-ACTIVATING PROTEIN 29 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;molecular function regulator#GO:0098772;enzyme activator activity#GO:0008047;nucleoside-triphosphatase activity#GO:0017111;enzyme regulator activity#GO:0030234 regulation of GTPase activity#GO:0043087;regulation of molecular function#GO:0065009;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;biological regulation#GO:0065007;positive regulation of molecular function#GO:0044093;regulation of hydrolase activity#GO:0051336;regulation of catalytic activity#GO:0050790;positive regulation of hydrolase activity#GO:0051345 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=4427|UniProtKB=Q13439 Q13439 GOLGA4 PTHR19327:SF0 GOLGIN GOLGIN SUBFAMILY A MEMBER 4 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=25507|UniProtKB=Q08AM6 Q08AM6 VAC14 PTHR16023:SF0 TAX1 BINDING PROTEIN-RELATED PROTEIN VAC14 HOMOLOG lipid metabolic process#GO:0006629;regulation of phosphate metabolic process#GO:0019220;phospholipid biosynthetic process#GO:0008654;phosphatidylinositol biosynthetic process#GO:0006661;organophosphate biosynthetic process#GO:0090407;positive regulation of cellular metabolic process#GO:0031325;positive regulation of molecular function#GO:0044093;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;regulation of catalytic activity#GO:0050790;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of transferase activity#GO:0051347;glycerolipid metabolic process#GO:0046486;positive regulation of metabolic process#GO:0009893;regulation of molecular function#GO:0065009;phosphorylation#GO:0016310;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;metabolic process#GO:0008152;positive regulation of phosphorylation#GO:0042327;positive regulation of catalytic activity#GO:0043085;glycerolipid biosynthetic process#GO:0045017;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;positive regulation of phosphate metabolic process#GO:0045937;regulation of cellular process#GO:0050794;glycerophospholipid biosynthetic process#GO:0046474;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;regulation of transferase activity#GO:0051338;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex#GO:0005942;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;phosphatidylinositol 3-kinase complex, class III#GO:0035032;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;transferase complex, transferring phosphorus-containing groups#GO:0061695;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 HUMAN|HGNC=18988|UniProtKB=O94900 O94900 TOX PTHR45781:SF4 AGAP000281-PA THYMOCYTE SELECTION-ASSOCIATED HIGH MOBILITY GROUP BOX PROTEIN TOX heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;animal organ development#GO:0048513;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;hemopoiesis#GO:0030097;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;immune system development#GO:0002520;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;leukocyte differentiation#GO:0002521;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=169|UniProtKB=P61160 P61160 ACTR2 PTHR11937:SF409 ACTIN ACTIN-RELATED PROTEIN 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;actin binding#GO:0003779;binding#GO:0005488;actin filament binding#GO:0051015 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;positive regulation of actin filament polymerization#GO:0030838;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of protein polymerization#GO:0032273;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;positive regulation of cellular component organization#GO:0051130;protein polymerization#GO:0051258;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cortical cytoskeleton#GO:0030863;Arp2/3 protein complex#GO:0005885;cortical actin cytoskeleton#GO:0030864;actin cortical patch#GO:0030479;cellular anatomical entity#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;actin cytoskeleton#GO:0015629;intracellular#GO:0005622;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 Alzheimer disease-presenilin pathway#P00004>actin#P00114;Huntington disease#P00029>Actin#P00807;Cadherin signaling pathway#P00012>F-actin#P00470 HUMAN|HGNC=37146|UniProtKB=A6NCK2 A6NCK2 TRIM43B PTHR24103:SF621 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 43-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=19844|UniProtKB=Q147X3 Q147X3 NAA30 PTHR45896:SF1 N-ALPHA-ACETYLTRANSFERASE 30 N-ALPHA-ACETYLTRANSFERASE 30 transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;peptide N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;peptide alpha-N-acetyltransferase activity#GO:0004596;N-acyltransferase activity#GO:0016410 macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein maturation#GO:0051604;protein modification process#GO:0036211;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;protein acylation#GO:0043543;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;N-terminal protein amino acid acetylation#GO:0006474;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein acetylation#GO:0006473;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical entity#GO:0110165 acetyltransferase#PC00038 HUMAN|HGNC=28519|UniProtKB=Q8NCR3 Q8NCR3 MFI PTHR33504:SF2 NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4 PROTEIN MFI dehydrogenase#PC00092 HUMAN|HGNC=4312|UniProtKB=P48507 P48507 GCLM PTHR13295:SF4 GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT GLUTAMATE--CYSTEINE LIGASE REGULATORY SUBUNIT molecular function regulator#GO:0098772;enzyme regulator activity#GO:0030234;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;positive regulation of catalytic activity#GO:0043085;peptide metabolic process#GO:0006518;organonitrogen compound biosynthetic process#GO:1901566;positive regulation of molecular function#GO:0044093;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;regulation of molecular function#GO:0065009;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular modified amino acid metabolic process#GO:0006575;biological regulation#GO:0065007;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494 ligase#PC00142 HUMAN|HGNC=6381|UniProtKB=O15229 O15229 KMO PTHR46028:SF2 KYNURENINE 3-MONOOXYGENASE KYNURENINE 3-MONOOXYGENASE nucleotide binding#GO:0000166;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular amino acid metabolic process#GO:0006520;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 oxygenase#PC00177 HUMAN|HGNC=30189|UniProtKB=O43824 O43824 GTPBP6 PTHR10229:SF0 GTP-BINDING PROTEIN HFLX GTP-BINDING PROTEIN 6-RELATED ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=8997|UniProtKB=P48426 P48426 PIP4K2A PTHR23086:SF21 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 ALPHA kinase#PC00137 HUMAN|HGNC=17989|UniProtKB=Q96S37 Q96S37 SLC22A12 PTHR24064:SF205 SOLUTE CARRIER FAMILY 22 MEMBER SOLUTE CARRIER FAMILY 22 MEMBER 12 localization#GO:0051179;organic substance transport#GO:0071702;establishment of localization#GO:0051234;organic anion transport#GO:0015711;anion transport#GO:0006820;ion transport#GO:0006811;transport#GO:0006810 secondary carrier transporter#PC00258 HUMAN|HGNC=18596|UniProtKB=Q14390 Q14390 GGTLC2 PTHR45027:SF5 PUTATIVE GLUTATHIONE HYDROLASE LIGHT CHAIN GLUTATHIONE HYDROLASE LIGHT CHAIN 2 hydrolase#PC00121 HUMAN|HGNC=12182|UniProtKB=A0A5A6 A0A5A6 TRBV11-3 PTHR23268:SF97 T-CELL RECEPTOR BETA CHAIN T CELL RECEPTOR BETA VARIABLE 11-3 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=7632|UniProtKB=P54802 P54802 NAGLU PTHR12872:SF1 ALPHA-N-ACETYLGLUCOSAMINIDASE ALPHA-N-ACETYLGLUCOSAMINIDASE HUMAN|HGNC=19117|UniProtKB=Q6ZNL6 Q6ZNL6 FGD5 PTHR12673:SF13 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 5 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=13968|UniProtKB=P59922 P59922 OR2B8P PTHR26453:SF636 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2B8-RELATED transmembrane signal receptor#PC00197 HUMAN|HGNC=2908|UniProtKB=O00548 O00548 DLL1 PTHR24044:SF380 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of cell communication#GO:0010646;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cell communication#GO:0007154;cellular process#GO:0009987;negative regulation of Notch signaling pathway#GO:0045746;regulation of Notch signaling pathway#GO:0008593;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;Notch signaling pathway#GO:0007219 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 Notch signaling pathway#P00045>Delta#P01116;Angiogenesis#P00005>Delta/Serrate#P00226 HUMAN|HGNC=31418|UniProtKB=Q5VYM1 Q5VYM1 C9orf131 PTHR21777:SF0 RCG55159-LIKE RCG55159-LIKE HUMAN|HGNC=14855|UniProtKB=Q8NGP2 Q8NGP2 OR8J1 PTHR48018:SF44 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 8J1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;system process#GO:0003008;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;multicellular organismal process#GO:0032501;sensory perception of chemical stimulus#GO:0007606;cell communication#GO:0007154;sensory perception#GO:0007600;nervous system process#GO:0050877;cellular process#GO:0009987;signaling#GO:0023052 transmembrane signal receptor#PC00197 HUMAN|HGNC=15888|UniProtKB=Q9NZ71 Q9NZ71 RTEL1 PTHR11472:SF62 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER REGULATOR OF TELOMERE ELONGATION HELICASE 1 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;helicase activity#GO:0004386;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;DNA-dependent ATPase activity#GO:0008094;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;DNA helicase activity#GO:0003678;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168;ATP binding#GO:0005524;ATPase activity#GO:0016887 DNA repair#GO:0006281;cellular component biogenesis#GO:0044085;regulation of double-strand break repair#GO:2000779;regulation of response to DNA damage stimulus#GO:2001020;regulation of nitrogen compound metabolic process#GO:0051171;negative regulation of chromosome organization#GO:2001251;regulation of cellular component organization#GO:0051128;regulation of telomere maintenance#GO:0032204;nucleobase-containing compound metabolic process#GO:0006139;DNA geometric change#GO:0032392;regulation of biological process#GO:0050789;regulation of cellular response to stress#GO:0080135;regulation of biological quality#GO:0065008;nitrogen compound metabolic process#GO:0006807;regulation of cellular component biogenesis#GO:0044087;recombinational repair#GO:0000725;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA metabolic process#GO:0051053;organic substance metabolic process#GO:0071704;cellular component assembly#GO:0022607;macromolecule metabolic process#GO:0043170;regulation of organelle organization#GO:0033043;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;double-strand break repair via homologous recombination#GO:0000724;DNA recombination#GO:0006310;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;chromosome organization#GO:0051276;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;double-strand break repair#GO:0006302;telomere organization#GO:0032200;regulation of DNA metabolic process#GO:0051052;cellular macromolecule metabolic process#GO:0044260;regulation of DNA repair#GO:0006282;regulation of double-strand break repair via homologous recombination#GO:0010569;telomere maintenance#GO:0000723;organic cyclic compound metabolic process#GO:1901360;negative regulation of organelle organization#GO:0010639;DNA duplex unwinding#GO:0032508;negative regulation of DNA recombination#GO:0045910;negative regulation of cellular process#GO:0048523;anatomical structure homeostasis#GO:0060249;metabolic process#GO:0008152;regulation of chromosome organization#GO:0033044;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;regulation of response to stress#GO:0080134;homeostatic process#GO:0042592;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;DNA conformation change#GO:0071103;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of DNA recombination#GO:0000018;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 DNA helicase#PC00011 HUMAN|HGNC=22214|UniProtKB=Q7Z6L1 Q7Z6L1 TECPR1 PTHR23250:SF1 DYSFERLIN-RELATED TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 1 phosphatidylinositol-3-phosphate binding#GO:0032266;binding#GO:0005488;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543 bounding membrane of organelle#GO:0098588;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;lytic vacuole#GO:0000323;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;autophagosome#GO:0005776;whole membrane#GO:0098805;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lysosome#GO:0005764;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227 HUMAN|HGNC=14967|UniProtKB=Q9HBV2 Q9HBV2 SPACA1 PTHR47223:SF1 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 1 SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 1 male gamete generation#GO:0048232;cellular component biogenesis#GO:0044085;cellular process involved in reproduction in multicellular organism#GO:0022412;developmental process#GO:0032502;endomembrane system organization#GO:0010256;spermatid differentiation#GO:0048515;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;spermatogenesis#GO:0007283;reproductive process#GO:0022414;vesicle organization#GO:0016050;multi-organism reproductive process#GO:0044703;multicellular organismal reproductive process#GO:0048609;germ cell development#GO:0007281;cellular developmental process#GO:0048869;cellular component assembly#GO:0022607;cellular component assembly involved in morphogenesis#GO:0010927;gamete generation#GO:0007276;multicellular organism reproduction#GO:0032504;cellular component organization#GO:0016043;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;multi-organism process#GO:0051704;cellular component morphogenesis#GO:0032989;organelle assembly#GO:0070925;cell development#GO:0048468;developmental process involved in reproduction#GO:0003006;cellular component organization or biogenesis#GO:0071840;spermatid development#GO:0007286;reproduction#GO:0000003;organelle organization#GO:0006996;anatomical structure development#GO:0048856;sexual reproduction#GO:0019953;multicellular organismal process#GO:0032501 bounding membrane of organelle#GO:0098588;acrosomal vesicle#GO:0001669;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;secretory granule membrane#GO:0030667;secretory granule#GO:0030141;vacuole#GO:0005773;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;secretory vesicle#GO:0099503;plasma membrane#GO:0005886 HUMAN|HGNC=19293|UniProtKB=P59282 P59282 TPPP2 PTHR12932:SF21 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 2 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;tubulin binding#GO:0015631;binding#GO:0005488 cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;cellular protein-containing complex assembly#GO:0034622;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;regulation of cellular component organization#GO:0051128;cellular component organization#GO:0016043;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;positive regulation of protein polymerization#GO:0032273;positive regulation of protein-containing complex assembly#GO:0031334;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of protein-containing complex assembly#GO:0043254;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;cytoskeleton organization#GO:0007010;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;microtubule#GO:0005874 non-motor microtubule binding protein#PC00166 HUMAN|HGNC=18627|UniProtKB=P60673 P60673 PFN3 PTHR13936:SF2 PROFILIN PROFILIN-3 cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;actin binding#GO:0003779;binding#GO:0005488 cellular component biogenesis#GO:0044085;positive regulation of supramolecular fiber organization#GO:1902905;positive regulation of organelle organization#GO:0010638;protein-containing complex assembly#GO:0065003;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;regulation of actin polymerization or depolymerization#GO:0008064;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;regulation of cellular component biogenesis#GO:0044087;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament-based process#GO:0032970;positive regulation of cellular component biogenesis#GO:0044089;regulation of protein polymerization#GO:0032271;positive regulation of biological process#GO:0048518;protein-containing complex subunit organization#GO:0043933;regulation of anatomical structure size#GO:0090066;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;regulation of actin filament length#GO:0030832;regulation of organelle organization#GO:0033043;actin filament bundle assembly#GO:0051017;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament bundle organization#GO:0061572;regulation of actin filament polymerization#GO:0030833;regulation of cellular component size#GO:0032535;positive regulation of cellular process#GO:0048522;regulation of supramolecular fiber organization#GO:1902903;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;protein polymerization#GO:0051258;positive regulation of cellular component organization#GO:0051130;positive regulation of cytoskeleton organization#GO:0051495;actin cytoskeleton organization#GO:0030036 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 HUMAN|HGNC=29204|UniProtKB=Q8N300 Q8N300 SVBP PTHR34762:SF1 SMALL VASOHIBIN-BINDING PROTEIN SMALL VASOHIBIN-BINDING PROTEIN negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;macromolecule localization#GO:0033036;macromolecule modification#GO:0043412;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;transport#GO:0006810;nitrogen compound transport#GO:0071705;protein modification process#GO:0036211;protein secretion#GO:0009306;peptide secretion#GO:0002790;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;negative regulation of protein modification process#GO:0031400;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;secretion#GO:0046903;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;negative regulation of cellular process#GO:0048523;secretion by cell#GO:0032940;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;peptide transport#GO:0015833;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;cellular protein modification process#GO:0006464;protein localization#GO:0008104;primary metabolic process#GO:0044238;localization#GO:0051179;regulation of primary metabolic process#GO:0080090;establishment of protein localization to extracellular region#GO:0035592;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein ubiquitination#GO:0031397;negative regulation of macromolecule metabolic process#GO:0010605;protein transport#GO:0015031;biological regulation#GO:0065007;protein localization to extracellular region#GO:0071692;regulation of metabolic process#GO:0019222;export from cell#GO:0140352;regulation of cellular metabolic process#GO:0031323 cellular anatomical entity#GO:0110165;apical part of cell#GO:0045177 HUMAN|HGNC=21943|UniProtKB=A6NGB7 A6NGB7 TMEM221 PTHR36132:SF1 TRANSMEMBRANE PROTEIN 221 TRANSMEMBRANE PROTEIN 221 HUMAN|HGNC=17270|UniProtKB=Q96RG2 Q96RG2 PASK PTHR24346:SF51 MAP/MICROTUBULE AFFINITY-REGULATING KINASE PAS DOMAIN-CONTAINING SERINE/THREONINE-PROTEIN KINASE transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 glucan metabolic process#GO:0044042;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;energy derivation by oxidation of organic compounds#GO:0015980;regulation of biological process#GO:0050789;cellular glucan metabolic process#GO:0006073;glucan biosynthetic process#GO:0009250;nitrogen compound metabolic process#GO:0006807;oxidation-reduction process#GO:0055114;intracellular signal transduction#GO:0035556;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;polysaccharide biosynthetic process#GO:0000271;glycogen metabolic process#GO:0005977;macromolecule metabolic process#GO:0043170;generation of precursor metabolites and energy#GO:0006091;cellular carbohydrate biosynthetic process#GO:0034637;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;cell communication#GO:0007154;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;polysaccharide metabolic process#GO:0005976;cellular carbohydrate metabolic process#GO:0044262;regulation of cellular process#GO:0050794;energy reserve metabolic process#GO:0006112;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;small molecule metabolic process#GO:0044281;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;monosaccharide metabolic process#GO:0005996;signal transduction#GO:0007165;negative regulation of biological process#GO:0048519;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biosynthetic process#GO:0009889;phosphorylation#GO:0016310;regulation of macromolecule biosynthetic process#GO:0010556;protein metabolic process#GO:0019538;signaling#GO:0023052;carbohydrate metabolic process#GO:0005975;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;cellular macromolecule biosynthetic process#GO:0034645;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;glycogen biosynthetic process#GO:0005978;glucose metabolic process#GO:0006006;regulation of glucose metabolic process#GO:0010906;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;hexose metabolic process#GO:0019318;cellular polysaccharide biosynthetic process#GO:0033692;regulation of cellular macromolecule biosynthetic process#GO:2000112;cellular polysaccharide metabolic process#GO:0044264 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=3155|UniProtKB=Q9H8V3 Q9H8V3 ECT2 PTHR16777:SF2 PROTEIN ECT2 PROTEIN ECT2 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;Ras guanyl-nucleotide exchange factor activity#GO:0005088;Rac GTPase binding#GO:0048365;GTPase binding#GO:0051020;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 cell division#GO:0051301;membrane organization#GO:0061024;nuclear division#GO:0000280;developmental process#GO:0032502;cell cycle process#GO:0022402;positive regulation of molecular function#GO:0044093;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;mitotic cell cycle process#GO:1903047;system development#GO:0048731;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;regulation of molecular function#GO:0065009;cytoskeleton-dependent cytokinesis#GO:0061640;regulation of hydrolase activity#GO:0051336;mitotic nuclear division#GO:0140014;cytokinesis#GO:0000910;membrane fission#GO:0090148;positive regulation of GTPase activity#GO:0043547;positive regulation of catalytic activity#GO:0043085;regulation of GTPase activity#GO:0043087;multicellular organism development#GO:0007275;cellular component organization#GO:0016043;cellular process#GO:0009987;positive regulation of hydrolase activity#GO:0051345;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;anatomical structure development#GO:0048856;biological regulation#GO:0065007;organelle fission#GO:0048285;multicellular organismal process#GO:0032501;cell cycle#GO:0007049 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113 HUMAN|HGNC=8319|UniProtKB=Q8NGJ0 Q8NGJ0 OR5A1 PTHR26452:SF354 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 5A1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;olfactory receptor activity#GO:0004984;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 HUMAN|HGNC=20811|UniProtKB=Q8N7K0 Q8N7K0 ZNF433 PTHR24379:SF94 KRAB AND ZINC FINGER DOMAIN-CONTAINING ZINC FINGER PROTEIN 433 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=21524|UniProtKB=Q9Y394 Q9Y394 DHRS7 PTHR44269:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7 dehydrogenase#PC00092 HUMAN|HGNC=8590|UniProtKB=Q13153 Q13153 PAK1 PTHR48015:SF20 SERINE/THREONINE-PROTEIN KINASE TAO SERINE/THREONINE-PROTEIN KINASE PAK 1 transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;cell projection organization#GO:0030030;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;regulation of cellular component organization#GO:0051128;positive regulation of protein modification process#GO:0031401;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;signal transduction by protein phosphorylation#GO:0023014;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;intracellular signal transduction#GO:0035556;axonogenesis#GO:0007409;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;cellular developmental process#GO:0048869;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;regulation of plasma membrane bounded cell projection organization#GO:0120035;cell communication#GO:0007154;positive regulation of macromolecule metabolic process#GO:0010604;stress-activated protein kinase signaling cascade#GO:0031098;regulation of neuron differentiation#GO:0045664;primary metabolic process#GO:0044238;regulation of neuron projection development#GO:0010975;cellular protein modification process#GO:0006464;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;response to stress#GO:0006950;positive regulation of phosphate metabolic process#GO:0045937;regulation of axonogenesis#GO:0050770;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of cell projection organization#GO:0031344;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;neuron development#GO:0048666;cellular response to stress#GO:0033554;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;regulation of cell morphogenesis involved in differentiation#GO:0010769;positive regulation of nitrogen compound metabolic process#GO:0051173;neurogenesis#GO:0022008;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;regulation of anatomical structure morphogenesis#GO:0022603;cellular macromolecule metabolic process#GO:0044260;developmental process#GO:0032502;positive regulation of molecular function#GO:0044093;activation of protein kinase activity#GO:0032147;protein modification process#GO:0036211;cell projection morphogenesis#GO:0048858;regulation of cell differentiation#GO:0045595;regulation of catalytic activity#GO:0050790;regulation of multicellular organismal development#GO:2000026;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;system development#GO:0048731;cell differentiation#GO:0030154;positive regulation of transferase activity#GO:0051347;positive regulation of metabolic process#GO:0009893;neuron differentiation#GO:0030182;phosphorylation#GO:0016310;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;protein metabolic process#GO:0019538;signaling#GO:0023052;metabolic process#GO:0008152;positive regulation of protein phosphorylation#GO:0001934;regulation of protein kinase activity#GO:0045859;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;regulation of cell development#GO:0060284;cell morphogenesis involved in differentiation#GO:0000904;positive regulation of catalytic activity#GO:0043085;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;cell development#GO:0048468;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;positive regulation of protein metabolic process#GO:0051247;regulation of cellular protein metabolic process#GO:0032268;cell morphogenesis involved in neuron differentiation#GO:0048667;regulation of neurogenesis#GO:0050767;positive regulation of protein kinase activity#GO:0045860;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;positive regulation of kinase activity#GO:0033674;generation of neurons#GO:0048699;positive regulation of cellular protein metabolic process#GO:0032270;regulation of transferase activity#GO:0051338 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Axon guidance mediated by semaphorins#P00007>PAK#P00331;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PAK#P00837;Cytoskeletal regulation by Rho GTPase#P00016>PAK#P00517;CCKR signaling map#P06959>PAK#P07091;CCKR signaling map#P06959>PAK1#P07065;T cell activation#P00053>PAK#P01319;Angiogenesis#P00005>PAK#P00249;Ras Pathway#P04393>PAK#P04553 HUMAN|HGNC=6715|UniProtKB=Q14767 Q14767 LTBP2 PTHR24034:SF49 EGF-LIKE DOMAIN-CONTAINING PROTEIN LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 2 binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;supramolecular fiber organization#GO:0097435 extracellular matrix structural protein#PC00103 HUMAN|HGNC=31665|UniProtKB=Q6P461 Q6P461 ACSM6 PTHR43605:SF1 ACYL-COENZYME A SYNTHETASE ACYL-COENZYME A SYNTHETASE ACSM6, MITOCHONDRIAL transferase activity, transferring acyl groups other than amino-acyl groups#GO:0016747;transferase activity, transferring acyl groups#GO:0016746;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular aromatic compound metabolic process#GO:0006725;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;carboxylic acid biosynthetic process#GO:0046394;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;fatty acid biosynthetic process#GO:0006633;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;organic acid biosynthetic process#GO:0016053;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ribonucleotide metabolic process#GO:0009259;monocarboxylic acid metabolic process#GO:0032787;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;fatty acid metabolic process#GO:0006631;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleotide metabolic process#GO:0009117;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281;cellular amide metabolic process#GO:0043603 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ligase#PC00142 HUMAN|HGNC=14240|UniProtKB=Q9NY59 Q9NY59 SMPD3 PTHR16320:SF8 SPHINGOMYELINASE FAMILY MEMBER SPHINGOMYELIN PHOSPHODIESTERASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;phospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;phospholipid metabolic process#GO:0006644;sphingolipid metabolic process#GO:0006665;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;membrane lipid metabolic process#GO:0006643;nitrogen compound metabolic process#GO:0006807;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;organic substance metabolic process#GO:0071704;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=5735|UniProtKB=A0A075B6S5 A0A075B6S5 IGKV1-27 PTHR23267:SF458 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-27 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=25768|UniProtKB=Q96BU1 Q96BU1 S100PBP PTHR14455:SF0 ASKOPOS S100P-BINDING PROTEIN HUMAN|HGNC=1809|UniProtKB=Q9Y6F8 Q9Y6F8 CDY1 PTHR43684:SF6 FAMILY NOT NAMED TESTIS-SPECIFIC CHROMODOMAIN PROTEIN Y 1-RELATED transcription coregulator activity#GO:0003712;molecular function regulator#GO:0098772;transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=30696|UniProtKB=Q8NI36 Q8NI36 WDR36 PTHR22840:SF12 WD REPEAT-CONTAINING PROTEIN 36 WD REPEAT-CONTAINING PROTEIN 36 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;rRNA processing#GO:0006364;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;t-UTP complex#GO:0034455;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nuclear lumen#GO:0031981;90S preribosome#GO:0030686 HUMAN|HGNC=16384|UniProtKB=Q13263 Q13263 TRIM28 PTHR25462:SF274 BONUS, ISOFORM C-RELATED TRANSCRIPTION INTERMEDIARY FACTOR 1-BETA negative regulation of gene expression#GO:0010629;response to external biotic stimulus#GO:0043207;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;cellular protein metabolic process#GO:0044267;defense response#GO:0006952;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;cellular protein modification process#GO:0006464;nucleobase-containing compound biosynthetic process#GO:0034654;response to stress#GO:0006950;defense response to other organism#GO:0098542;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;peptidyl-lysine modification#GO:0018205;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;immune response#GO:0006955;protein sumoylation#GO:0016925;organonitrogen compound metabolic process#GO:1901564;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;immune system process#GO:0002376;response to external stimulus#GO:0009605;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to other organism#GO:0051707;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;regulation of cellular macromolecule biosynthetic process#GO:2000112 RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 HUMAN|HGNC=16099|UniProtKB=Q6ZNI0 Q6ZNI0 GCNT7 PTHR19297:SF178 GLYCOSYLTRANSFERASE 14 FAMILY MEMBER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 glycosyltransferase#PC00111 HUMAN|HGNC=28194|UniProtKB=Q9BRP1 Q9BRP1 PDCD2L PTHR46421:SF1 PROGRAMMED CELL DEATH PROTEIN 2-LIKE PROGRAMMED CELL DEATH PROTEIN 2-LIKE HUMAN|HGNC=28899|UniProtKB=Q86V85 Q86V85 GPR180 PTHR23252:SF29 INTIMAL THICKNESS RECEPTOR-RELATED INTEGRAL MEMBRANE PROTEIN GPR180 HUMAN|HGNC=20868|UniProtKB=Q8N680 Q8N680 ZBTB2 PTHR24399:SF0 ZINC FINGER AND BTB DOMAIN-CONTAINING ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 2 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 negative regulation of gene expression#GO:0010629;negative regulation of cellular macromolecule biosynthetic process#GO:2000113;regulation of nitrogen compound metabolic process#GO:0051171;gene expression#GO:0010467;negative regulation of nucleic acid-templated transcription#GO:1903507;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;organic substance metabolic process#GO:0071704;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;negative regulation of metabolic process#GO:0009892;cellular nitrogen compound metabolic process#GO:0034641;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of transcription, DNA-templated#GO:0045892;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;negative regulation of cellular biosynthetic process#GO:0031327;regulation of cellular metabolic process#GO:0031323;cellular aromatic compound metabolic process#GO:0006725;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;negative regulation of RNA metabolic process#GO:0051253;RNA metabolic process#GO:0016070;negative regulation of RNA biosynthetic process#GO:1902679;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;cytokine production#GO:0001816;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of immune system process#GO:0002682;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of cytokine production#GO:0001817;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;immune system process#GO:0002376;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of cellular macromolecule biosynthetic process#GO:2000112 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=18582|UniProtKB=O95490 O95490 ADGRL2 PTHR12011:SF61 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR L2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 head development#GO:0060322;regulation of adenylate cyclase activity#GO:0045761;signal transduction#GO:0007165;second-messenger-mediated signaling#GO:0019932;animal organ development#GO:0048513;regulation of cyclase activity#GO:0031279;developmental process#GO:0032502;regulation of signaling#GO:0023051;brain development#GO:0007420;regulation of catalytic activity#GO:0050790;nervous system development#GO:0007399;regulation of cAMP-mediated signaling#GO:0043949;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;central nervous system development#GO:0007417;intracellular signal transduction#GO:0035556;signaling#GO:0023052;activation of adenylate cyclase activity#GO:0007190;regulation of cell communication#GO:0010646;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of lyase activity#GO:0051339;cellular response to stimulus#GO:0051716;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger#GO:0007187;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;G protein-coupled receptor signaling pathway#GO:0007186;cAMP-mediated signaling#GO:0019933;cyclic-nucleotide-mediated signaling#GO:0019935 intrinsic component of membrane#GO:0031224;neuron projection#GO:0043005;integral component of plasma membrane#GO:0005887;plasma membrane region#GO:0098590;intrinsic component of plasma membrane#GO:0031226;cell projection#GO:0042995;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=23475|UniProtKB=Q8N5W8 Q8N5W8 FAM24B PTHR35860:SF5 PROTEIN FAM24B PROTEIN FAM24B HUMAN|HGNC=67|UniProtKB=P28288 P28288 ABCD3 PTHR11384:SF62 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 3 transporter activity#GO:0005215;lipid transporter activity#GO:0005319 lipid metabolic process#GO:0006629;monocarboxylic acid transport#GO:0015718;cellular localization#GO:0051641;macromolecule localization#GO:0033036;organic acid transport#GO:0015849;transport#GO:0006810;very long-chain fatty acid metabolic process#GO:0000038;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;lipid transport#GO:0006869;anion transmembrane transport#GO:0098656;carboxylic acid transmembrane transport#GO:1905039;organic substance transport#GO:0071702;peroxisomal transport#GO:0043574;establishment of localization#GO:0051234;anion transport#GO:0006820;fatty acid beta-oxidation#GO:0006635;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;lipid localization#GO:0010876;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;cellular lipid catabolic process#GO:0044242;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;transmembrane transport#GO:0055085;organic anion transport#GO:0015711;ion transport#GO:0006811;cellular metabolic process#GO:0044237;carboxylic acid transport#GO:0046942;lipid oxidation#GO:0034440;cellular component organization#GO:0016043;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;ion transmembrane transport#GO:0034220;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic acid catabolic process#GO:0016054;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;organic acid transmembrane transport#GO:1903825;intracellular transport#GO:0046907;cellular lipid metabolic process#GO:0044255;carboxylic acid metabolic process#GO:0019752;peroxisome organization#GO:0007031;long-chain fatty acid transport#GO:0015909;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281 bounding membrane of organelle#GO:0098588;microbody membrane#GO:0031903;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;whole membrane#GO:0098805 ATP-binding cassette (ABC) transporter#PC00003 HUMAN|HGNC=33169|UniProtKB=Q7RTU5 Q7RTU5 ASCL5 PTHR13935:SF55 ACHAETE-SCUTE TRANSCRIPTION FACTOR-RELATED ACHAETE-SCUTE HOMOLOG 5 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=24703|UniProtKB=Q3YEC7 Q3YEC7 RABL6 PTHR14932:SF1 RAS GTPASE-RELATED RAB-LIKE PROTEIN 6 carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 small GTPase#PC00208 HUMAN|HGNC=15600|UniProtKB=Q8TB52 Q8TB52 FBXO30 PTHR15933:SF13 PROTEIN CBG16327 F-BOX ONLY PROTEIN 30 HUMAN|HGNC=18706|UniProtKB=Q4V328 Q4V328 GRIPAP1 PTHR18978:SF1 GRIP-1 ASSOCIATED PROTEIN 1 GRIP1-ASSOCIATED PROTEIN 1 endosomal transport#GO:0016197;receptor localization to synapse#GO:0097120;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;regulation of synapse organization#GO:0050807;regulation of cellular component organization#GO:0051128;establishment of protein localization#GO:0045184;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of protein localization to membrane#GO:0090150;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;regulation of protein transport#GO:0051223;regulation of protein localization#GO:0032880;protein localization to plasma membrane#GO:0072659;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to synapse#GO:0035418;protein localization to membrane#GO:0072657;regulation of protein localization to membrane#GO:1905475;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;retrograde transport, endosome to plasma membrane#GO:1990126;cellular process#GO:0009987;peptide transport#GO:0015833;regulation of cellular localization#GO:0060341;protein localization#GO:0008104;localization#GO:0051179;protein localization to cell periphery#GO:1990778;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cellular macromolecule localization#GO:0070727;regulation of cellular process#GO:0050794;protein localization to cell junction#GO:1902414;cell junction organization#GO:0034330;protein transport#GO:0015031;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886;regulation of synapse structure or activity#GO:0050803;intracellular transport#GO:0046907;regulation of establishment of protein localization#GO:0070201;regulation of peptide transport#GO:0090087;vesicle-mediated transport in synapse#GO:0099003;protein-containing complex localization#GO:0031503 bounding membrane of organelle#GO:0098588;synapse#GO:0045202;endosome#GO:0005768;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;early endosome#GO:0005769;glutamatergic synapse#GO:0098978;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;extrinsic component of membrane#GO:0019898;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;postsynapse#GO:0098794;plasma membrane#GO:0005886 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=1772|UniProtKB=Q00526 Q00526 CDK3 PTHR24056:SF462 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 3 transferase activity#GO:0016740;cyclin-dependent protein kinase activity#GO:0097472;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 signal transduction#GO:0007165;mitotic cell cycle phase transition#GO:0044772;macromolecule modification#GO:0043412;nuclear division#GO:0000280;cell cycle G1/S phase transition#GO:0044843;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;positive regulation of cell population proliferation#GO:0008284;gene expression#GO:0010467;protein modification process#GO:0036211;cell population proliferation#GO:0008283;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;G1/S transition of mitotic cell cycle#GO:0000082;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;positive regulation of biological process#GO:0048518;signaling#GO:0023052;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of cell population proliferation#GO:0042127;regulation of mitotic cell cycle phase transition#GO:1901990;macromolecule metabolic process#GO:0043170;regulation of cell cycle phase transition#GO:1901987;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;protein phosphorylation#GO:0006468;cell communication#GO:0007154;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;regulation of cell cycle process#GO:0010564;positive regulation of cellular process#GO:0048522;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;G2/M transition of mitotic cell cycle#GO:0000086;regulation of macromolecule metabolic process#GO:0060255;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle#GO:0007346;cell cycle G2/M phase transition#GO:0044839;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular#GO:0005622;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 HUMAN|Gene=YJ005_HUMAN|UniProtKB=Q6ZSR9 Q6ZSR9 - PTHR47907:SF1 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN PROTEIN KINASE DOMAIN-CONTAINING PROTEIN HUMAN|HGNC=14086|UniProtKB=O60813 O60813 PRAMEF11 PTHR14224:SF100 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 PRAME FAMILY MEMBER 11-RELATED cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=16219|UniProtKB=Q8TEA8 Q8TEA8 DTD1 PTHR10472:SF5 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 1 catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 esterase#PC00097 HUMAN|HGNC=26371|UniProtKB=Q8N7E2 Q8N7E2 CBLL2 PTHR13480:SF1 E3 UBIQUITIN-PROTEIN LIGASE HAKAI-RELATED E3 UBIQUITIN-PROTEIN LIGASE CBLL2 ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;biological adhesion#GO:0022610;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;nitrogen compound metabolic process#GO:0006807;biological regulation#GO:0065007;protein metabolic process#GO:0019538;regulation of cell adhesion#GO:0030155;cellular protein metabolic process#GO:0044267;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=33454|UniProtKB=Q6NV74 Q6NV74 CRACDL PTHR47743:SF1 KIAA1210 / KIAA1211 FAMILY MEMBER CRACD-LIKE PROTEIN HUMAN|HGNC=5744|UniProtKB=A0A0C4DH69 A0A0C4DH69 IGKV1-9 PTHR23267:SF294 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN KAPPA VARIABLE 1-9 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=29676|UniProtKB=Q15397 Q15397 PUM3 PTHR13389:SF0 UNCHARACTERIZED PUMILIO HOMOLOG 3 RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;binding#GO:0005488;organic cyclic compound binding#GO:0097159 posttranscriptional regulation of gene expression#GO:0010608;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;gene expression#GO:0010467;biosynthetic process#GO:0009058;translation#GO:0006412;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of cellular amide metabolic process#GO:0034248;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;amide biosynthetic process#GO:0043604;regulation of primary metabolic process#GO:0080090;regulation of cellular protein metabolic process#GO:0032268;peptide biosynthetic process#GO:0043043;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of translation#GO:0006417;translational elongation#GO:0006414;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323;cellular amide metabolic process#GO:0043603 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12030|UniProtKB=Q15628 Q15628 TRADD PTHR14913:SF0 TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein binding#GO:0005515;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;receptor tyrosine kinase binding#GO:0030971;signaling receptor binding#GO:0005102;kinase binding#GO:0019900 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;extrinsic apoptotic signaling pathway#GO:0097191;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;apoptotic process#GO:0006915;biological regulation#GO:0065007;cell death#GO:0008219;programmed cell death#GO:0012501;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 receptor complex#GO:0043235;protein-containing complex#GO:0032991 Apoptosis signaling pathway#P00006>TRADD#P00319 HUMAN|HGNC=10346|UniProtKB=Q969Q0 Q969Q0 RPL36AL PTHR10369:SF45 60S RIBOSOMAL PROTEIN L36A/L44 60S RIBOSOMAL PROTEIN L36A-LIKE cytoplasm#GO:0005737;intracellular non-membrane-bounded organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;intracellular#GO:0005622;cytosolic large ribosomal subunit#GO:0022625;large ribosomal subunit#GO:0015934;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=14842|UniProtKB=Q8NGN6 Q8NGN6 OR10G7 PTHR26453:SF7 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 10G7 transmembrane signal receptor#PC00197 HUMAN|HGNC=3071|UniProtKB=Q16690 Q16690 DUSP5 PTHR10159:SF40 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE 5 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;enzyme binding#GO:0019899;phosphoprotein phosphatase activity#GO:0004721;kinase activity#GO:0016301;kinase binding#GO:0019900;phosphoric ester hydrolase activity#GO:0042578;protein kinase activity#GO:0004672;transferase activity#GO:0016740;MAP kinase activity#GO:0004707;hydrolase activity#GO:0016787;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;protein kinase binding#GO:0019901;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of protein modification process#GO:0031399;peptidyl-tyrosine dephosphorylation#GO:0035335;regulation of protein metabolic process#GO:0051246;negative regulation of kinase activity#GO:0033673;regulation of nitrogen compound metabolic process#GO:0051171;ectoderm formation#GO:0001705;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;signal transduction by protein phosphorylation#GO:0023014;negative regulation of protein phosphorylation#GO:0001933;regulation of phosphorus metabolic process#GO:0051174;negative regulation of protein modification process#GO:0031400;negative regulation of MAPK cascade#GO:0043409;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;mesoderm morphogenesis#GO:0048332;intracellular signal transduction#GO:0035556;regulation of MAP kinase activity#GO:0043405;cellular protein metabolic process#GO:0044267;negative regulation of cell communication#GO:0010648;gastrulation#GO:0007369;endoderm development#GO:0007492;organic substance metabolic process#GO:0071704;regulation of kinase activity#GO:0043549;ectoderm development#GO:0007398;macromolecule metabolic process#GO:0043170;negative regulation of signaling#GO:0023057;protein dephosphorylation#GO:0006470;cellular metabolic process#GO:0044237;cell communication#GO:0007154;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;regulation of response to stimulus#GO:0048583;embryo development#GO:0009790;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;mesoderm formation#GO:0001707;macromolecule modification#GO:0043412;negative regulation of intracellular signal transduction#GO:1902532;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;developmental process#GO:0032502;protein modification process#GO:0036211;MAPK cascade#GO:0000165;regulation of catalytic activity#GO:0050790;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;endoderm formation#GO:0001706;regulation of protein serine/threonine kinase activity#GO:0071900;phosphorylation#GO:0016310;negative regulation of protein kinase activity#GO:0006469;protein metabolic process#GO:0019538;negative regulation of transferase activity#GO:0051348;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of MAP kinase activity#GO:0043407;regulation of protein kinase activity#GO:0045859;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;negative regulation of response to stimulus#GO:0048585;negative regulation of phosphorus metabolic process#GO:0010563;multicellular organism development#GO:0007275;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;cellular process#GO:0009987;anatomical structure formation involved in morphogenesis#GO:0048646;tissue development#GO:0009888;mesoderm development#GO:0007498;regulation of primary metabolic process#GO:0080090;response to stimulus#GO:0050896;regulation of cellular protein metabolic process#GO:0032268;negative regulation of cellular protein metabolic process#GO:0032269;regulation of macromolecule metabolic process#GO:0060255;negative regulation of phosphorylation#GO:0042326;formation of primary germ layer#GO:0001704;negative regulation of macromolecule metabolic process#GO:0010605;dephosphorylation#GO:0016311;biological regulation#GO:0065007;negative regulation of phosphate metabolic process#GO:0045936;tissue morphogenesis#GO:0048729;embryonic morphogenesis#GO:0048598;negative regulation of catalytic activity#GO:0043086;regulation of transferase activity#GO:0051338;negative regulation of molecular function#GO:0044092 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 HUMAN|HGNC=25281|UniProtKB=Q08ER8 Q08ER8 ZNF543 PTHR24377:SF812 IP01015P-RELATED ZINC FINGER PROTEIN 543 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 HUMAN|HGNC=17089|UniProtKB=Q8NF91 Q8NF91 SYNE1 PTHR14514:SF3 PKA ANCHORING PROTEIN NESPRIN-1 HUMAN|HGNC=9979|UniProtKB=O75678 O75678 RFPL2 PTHR25462:SF289 BONUS, ISOFORM C-RELATED RET FINGER PROTEIN-LIKE 1-RELATED HUMAN|HGNC=13599|UniProtKB=Q9UKT7 Q9UKT7 FBXL3 PTHR16134:SF5 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX/LRR-REPEAT PROTEIN 3 rhythmic process#GO:0048511;mitotic cell cycle phase transition#GO:0044772;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;mitotic cell cycle process#GO:1903047;modification-dependent macromolecule catabolic process#GO:0043632;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;response to radiation#GO:0009314;proteolysis#GO:0006508;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;catabolic process#GO:0009056;mitotic nuclear division#GO:0140014;proteasomal protein catabolic process#GO:0010498;response to abiotic stimulus#GO:0009628;organic substance catabolic process#GO:1901575;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;modification-dependent protein catabolic process#GO:0019941;response to light stimulus#GO:0009416;circadian rhythm#GO:0007623;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle phase transition#GO:0044770;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;cellular component organization or biogenesis#GO:0071840;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;G2/M transition of mitotic cell cycle#GO:0000086;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;cellular protein catabolic process#GO:0044257;biological regulation#GO:0065007;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;organelle fission#GO:0048285;cellular macromolecule catabolic process#GO:0044265;proteolysis involved in cellular protein catabolic process#GO:0051603;regulation of circadian rhythm#GO:0042752;cell cycle G2/M phase transition#GO:0044839 SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular#GO:0005622;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=25536|UniProtKB=Q5D0E6 Q5D0E6 DALRD3 PTHR16043:SF1 DALRD3 PROTEIN DALR ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 3 HUMAN|HGNC=8242|UniProtKB=O95371 O95371 OR2C1 PTHR26453:SF237 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2C1 transmembrane signal receptor#PC00197 HUMAN|HGNC=2193|UniProtKB=Q07092 Q07092 COL16A1 PTHR24023:SF372 COLLAGEN ALPHA COLLAGEN ALPHA-1(XVI) CHAIN structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 Integrin signalling pathway#P00034>Integrin alpha#P00941;Integrin signalling pathway#P00034>Collagen#P00922 HUMAN|HGNC=37253|UniProtKB=Q6ZV50 Q6ZV50 RFX8 PTHR12619:SF24 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX8 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=11040|UniProtKB=Q92911 Q92911 SLC5A5 PTHR42985:SF11 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER SODIUM/IODIDE COTRANSPORTER symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 monovalent inorganic cation transport#GO:0015672;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;ion transport#GO:0006811;transport#GO:0006810;cation transport#GO:0006812;inorganic ion transmembrane transport#GO:0098660;cellular process#GO:0009987;ion transmembrane transport#GO:0034220;anion transmembrane transport#GO:0098656;inorganic anion transmembrane transport#GO:0098661;localization#GO:0051179;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;anion transport#GO:0006820;inorganic anion transport#GO:0015698 secondary carrier transporter#PC00258 HUMAN|HGNC=24245|UniProtKB=Q96MC2 Q96MC2 DRC1 PTHR21625:SF1 NYD-SP28 PROTEIN DYNEIN REGULATORY COMPLEX PROTEIN 1 microtubule-based protein transport#GO:0099118;cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;organelle localization#GO:0051640;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;nitrogen compound transport#GO:0071705;regulation of localization#GO:0032879;axoneme assembly#GO:0035082;plasma membrane bounded cell projection organization#GO:0120036;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;establishment of vesicle localization#GO:0051650;cytoskeleton organization#GO:0007010;establishment of organelle localization#GO:0051656;protein-containing complex subunit organization#GO:0043933;regulation of cellular component movement#GO:0051270;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;cilium assembly#GO:0060271;cilium or flagellum-dependent cell motility#GO:0001539;vesicle-mediated transport#GO:0016192;localization of cell#GO:0051674;cellular component organization#GO:0016043;vesicle targeting, trans-Golgi to periciliary membrane compartment#GO:0097712;peptide transport#GO:0015833;transport along microtubule#GO:0010970;intraciliary transport#GO:0042073;protein localization#GO:0008104;cilium movement#GO:0003341;cellular component organization or biogenesis#GO:0071840;cellular macromolecule localization#GO:0070727;protein transport along microtubule#GO:0098840;regulation of cellular process#GO:0050794;axonemal dynein complex assembly#GO:0070286;protein transport#GO:0015031;movement of cell or subcellular component#GO:0006928;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;locomotion#GO:0040011;protein-containing complex localization#GO:0031503;vesicle targeting, to, from or within Golgi#GO:0048199;cilium organization#GO:0044782;regulation of microtubule-based process#GO:0032886;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;transport#GO:0006810;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;amide transport#GO:0042886;organic substance transport#GO:0071702;protein localization to cilium#GO:0061512;cytoskeleton-dependent intracellular transport#GO:0030705;protein localization to organelle#GO:0033365;vesicle localization#GO:0051648;cell motility#GO:0048870;intraciliary transport involved in cilium assembly#GO:0035735;Golgi vesicle transport#GO:0048193;vesicle targeting#GO:0006903;cellular process#GO:0009987;cell projection assembly#GO:0030031;localization#GO:0051179;organelle assembly#GO:0070925;cilium-dependent cell motility#GO:0060285;microtubule-based transport#GO:0099111;microtubule-based process#GO:0007017;organelle organization#GO:0006996;ciliary transition zone assembly#GO:1905349;microtubule bundle formation#GO:0001578;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;intracellular protein transport#GO:0006886 supramolecular complex#GO:0099080;axoneme#GO:0005930;cytoplasmic region#GO:0099568;supramolecular fiber#GO:0099512;cell periphery#GO:0071944;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;ciliary plasm#GO:0097014;cytoskeleton#GO:0005856;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;microtubule#GO:0005874;plasma membrane#GO:0005886 HUMAN|HGNC=20314|UniProtKB=Q86UA1 Q86UA1 PRPF39 PTHR17204:SF5 PRE-MRNA PROCESSING PROTEIN PRP39-RELATED PRE-MRNA-PROCESSING FACTOR 39 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site selection#GO:0006376;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;ribonucleoprotein complex biogenesis#GO:0022613;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 RNA splicing factor#PC00148 HUMAN|HGNC=19084|UniProtKB=Q86YT9 Q86YT9 JAML PTHR13869:SF22 MYELIN P0 RELATED JUNCTIONAL ADHESION MOLECULE-LIKE myelin protein#PC00161 HUMAN|HGNC=25983|UniProtKB=Q6NUQ4 Q6NUQ4 TMEM214 PTHR13448:SF0 TRANSMEMBRANE PROTEIN 214 TRANSMEMBRANE PROTEIN 214 cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vacuole#GO:0005773;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;plasma membrane#GO:0005886 HUMAN|HGNC=24456|UniProtKB=Q8NFT8 Q8NFT8 DNER PTHR24044:SF467 NOTCH LIGAND FAMILY MEMBER DELTA AND NOTCH-LIKE EPIDERMAL GROWTH FACTOR-RELATED RECEPTOR protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 HUMAN|HGNC=24690|UniProtKB=Q9BZ68 Q9BZ68 FRMD8P1 PTHR13283:SF12 KREV INTERACTION TRAPPED 1-RELATED FERM DOMAIN-CONTAINING PROTEIN FRMD8P1-RELATED scaffold/adaptor protein#PC00226 HUMAN|HGNC=10410|UniProtKB=P62266 P62266 RPS23 PTHR11652:SF44 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER 40S RIBOSOMAL PROTEIN S23 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;biosynthetic process#GO:0009058;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;translation#GO:0006412;amide biosynthetic process#GO:0043604;peptide biosynthetic process#GO:0043043;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;translational elongation#GO:0006414;cellular amide metabolic process#GO:0043603;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=28972|UniProtKB=Q8IXZ2 Q8IXZ2 ZC3H3 PTHR46156:SF1 CCCH ZINGC FINGER ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 3 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 HUMAN|HGNC=29641|UniProtKB=Q2TAK8 Q2TAK8 PWWP3A PTHR31333:SF4 PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3 FAMILY MEMBER PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3A nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;chromatin binding#GO:0003682 DNA repair#GO:0006281;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular response to DNA damage stimulus#GO:0006974;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;organic cyclic compound metabolic process#GO:1901360;organelle organization#GO:0006996;chromosome organization#GO:0051276;nitrogen compound metabolic process#GO:0006807;chromatin organization#GO:0006325;cellular response to stress#GO:0033554;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 HUMAN|HGNC=2995|UniProtKB=Q9H3H5 Q9H3H5 DPAGT1 PTHR10571:SF0 UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;macromolecule glycosylation#GO:0043413;lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein glycosylation#GO:0006486;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;protein N-linked glycosylation#GO:0006487;organophosphate metabolic process#GO:0019637;cellular lipid metabolic process#GO:0044255;glycosylation#GO:0070085 cellular anatomical entity#GO:0110165;intrinsic component of membrane#GO:0031224;integral component of membrane#GO:0016021;membrane#GO:0016020 glycosyltransferase#PC00111 HUMAN|HGNC=26209|UniProtKB=Q8N3Z6 Q8N3Z6 ZCCHC7 PTHR46543:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7 HUMAN|HGNC=20060|UniProtKB=Q70CQ4 Q70CQ4 USP31 PTHR21646:SF44 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 31 cysteine protease#PC00081 HUMAN|HGNC=4500|UniProtKB=O15529 O15529 GPR42 PTHR45822:SF6 FREE FATTY ACID RECEPTOR 2-RELATED FREE FATTY ACID RECEPTOR 3-RELATED HUMAN|HGNC=9801|UniProtKB=P63000 P63000 RAC1 PTHR24072:SF105 RHO FAMILY GTPASE RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 GTPase activity#GO:0003924;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;kinase binding#GO:0019900;pyrophosphatase activity#GO:0016462;purine nucleotide binding#GO:0017076;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;protein kinase binding#GO:0019901;ion binding#GO:0043167;nucleoside-triphosphatase activity#GO:0017111;anion binding#GO:0043168 neuron projection guidance#GO:0097485;cell projection organization#GO:0030030;membrane organization#GO:0061024;regulation of cellular component organization#GO:0051128;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;regulation of biological process#GO:0050789;regulation of cytoskeleton organization#GO:0051493;actin filament-based process#GO:0030029;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;membrane invagination#GO:0010324;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;cytoskeleton organization#GO:0007010;axonogenesis#GO:0007409;cellular developmental process#GO:0048869;phagocytosis#GO:0006909;regulation of organelle organization#GO:0033043;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;neuron projection development#GO:0031175;axon development#GO:0061564;regulation of cellular process#GO:0050794;regulation of cell morphogenesis#GO:0022604;anatomical structure development#GO:0048856;movement of cell or subcellular component#GO:0006928;neuron development#GO:0048666;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;apoptotic cell clearance#GO:0043277;locomotion#GO:0040011;taxis#GO:0042330;establishment or maintenance of cell polarity#GO:0007163;neurogenesis#GO:0022008;regulation of anatomical structure morphogenesis#GO:0022603;developmental process#GO:0032502;transport#GO:0006810;cell projection morphogenesis#GO:0048858;cell differentiation#GO:0030154;system development#GO:0048731;axon guidance#GO:0007411;supramolecular fiber organization#GO:0097435;regulation of actin cytoskeleton organization#GO:0032956;actin filament organization#GO:0007015;neuron differentiation#GO:0030182;vesicle organization#GO:0016050;regulation of actin filament-based process#GO:0032970;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell part morphogenesis#GO:0032990;chemotaxis#GO:0006935;cell morphogenesis involved in differentiation#GO:0000904;multicellular organism development#GO:0007275;cell morphogenesis#GO:0000902;cellular process#GO:0009987;cellular component morphogenesis#GO:0032989;localization#GO:0051179;cell development#GO:0048468;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;vesicle budding from membrane#GO:0006900;regulation of developmental process#GO:0050793;motor neuron axon guidance#GO:0008045;organelle organization#GO:0006996;cortical cytoskeleton organization#GO:0030865;biological regulation#GO:0065007;generation of neurons#GO:0048699;actin cytoskeleton organization#GO:0030036 synapse#GO:0045202;somatodendritic compartment#GO:0036477;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;dendrite#GO:0030425;cell periphery#GO:0071944;cell cortex#GO:0005938;dendritic tree#GO:0097447;cellular anatomical entity#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;neuron projection#GO:0043005;cytoplasmic vesicle#GO:0031410;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;postsynapse#GO:0098794;neuron spine#GO:0044309;cytoskeleton#GO:0005856;cell projection#GO:0042995;dendritic spine#GO:0043197;plasma membrane#GO:0005886 small GTPase#PC00208 T cell activation#P00053>rac#P01324;p38 MAPK pathway#P05918>Rac#P06021;Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;EGF receptor signaling pathway#P00018>Rac#P00564;Axon guidance mediated by semaphorins#P00007>Rac#P00340;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;B cell activation#P00010>Rac#P00385;Ras Pathway#P04393>Rac#P04559;Integrin signalling pathway#P00034>Rac#P00927;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;CCKR signaling map#P06959>RAC1-GDP#P07225;Huntington disease#P00029>Rac#P00775;CCKR signaling map#P06959>RAC1-GTP#P07214;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Rac#P00872;Gonadotropin-releasing hormone receptor pathway#P06664>Rac1#P06860;VEGF signaling pathway#P00056>Rac#P01421;Axon guidance mediated by netrin#P00009>Rac#P00366;FGF signaling pathway#P00021>Rac#P00645 HUMAN|HGNC=18562|UniProtKB=Q99581 Q99581 FEV PTHR11849:SF203 ETS PROTEIN FEV sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;cellular developmental process#GO:0048869;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 HUMAN|HGNC=15486|UniProtKB=Q9NZQ3 Q9NZQ3 NCKIPSD PTHR13357:SF1 SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN NCK-INTERACTING PROTEIN WITH SH3 DOMAIN scaffold/adaptor protein#PC00226 HUMAN|HGNC=21347|UniProtKB=Q7L2Z9 Q7L2Z9 CENPQ PTHR31345:SF3 CENTROMERE PROTEIN Q CENTROMERE PROTEIN Q nuclear chromosome segregation#GO:0098813;cellular localization#GO:0051641;organelle localization#GO:0051640;establishment of chromosome localization#GO:0051303;macromolecule localization#GO:0033036;cellular protein localization#GO:0034613;cell cycle process#GO:0022402;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of cellular localization#GO:0060341;chromosome segregation#GO:0007059;positive regulation of cellular process#GO:0048522;protein localization#GO:0008104;localization#GO:0051179;regulation of biological process#GO:0050789;metaphase plate congression#GO:0051310;cellular macromolecule localization#GO:0070727;protein localization to kinetochore#GO:0034501;establishment of localization#GO:0051234;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cell cycle#GO:0007049;establishment of localization in cell#GO:0051649;protein localization to organelle#GO:0033365;chromosome localization#GO:0050000;positive regulation of biological process#GO:0048518;establishment of organelle localization#GO:0051656;regulation of protein localization#GO:0032880 intracellular non-membrane-bounded organelle#GO:0043232;supramolecular complex#GO:0099080;non-membrane-bounded organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular#GO:0005622;chromosome, centromeric region#GO:0000775;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=37442|UniProtKB=A0A1B0GV03 A0A1B0GV03 GOLGA6L7 PTHR23143:SF22 TRICHOHYALIN-RELATED GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 7 actin or actin-binding cytoskeletal protein#PC00041 HUMAN|HGNC=21703|UniProtKB=Q9BPX7 Q9BPX7 C7orf25 PTHR13379:SF0 UNCHARACTERIZED DUF1308 UPF0415 PROTEIN C7ORF25 HUMAN|HGNC=6392|UniProtKB=Q02241 Q02241 KIF23 PTHR24115:SF600 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF23 pyrophosphatase activity#GO:0016462;cytoskeletal protein binding#GO:0008092;microtubule motor activity#GO:0003777;motor activity#GO:0003774;tubulin binding#GO:0015631;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;cytoskeleton#GO:0005856;microtubule#GO:0005874 microtubule binding motor protein#PC00156 HUMAN|HGNC=2680|UniProtKB=Q9BTC0 Q9BTC0 DIDO1 PTHR11477:SF13 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN DEATH-INDUCER OBLITERATOR 1 general transcription factor#PC00259 HUMAN|HGNC=33803|UniProtKB=Q2NL98 Q2NL98 VMAC PTHR34707:SF1 FAMILY NOT NAMED VIMENTIN-TYPE INTERMEDIATE FILAMENT-ASSOCIATED COILED-COIL PROTEIN supramolecular complex#GO:0099080;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intermediate filament#GO:0005882;intracellular#GO:0005622;intermediate filament cytoskeleton#GO:0045111;supramolecular polymer#GO:0099081;supramolecular fiber#GO:0099512;cellular anatomical entity#GO:0110165;cytoskeleton#GO:0005856;organelle#GO:0043226;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229 HUMAN|HGNC=14290|UniProtKB=Q8NFZ4 Q8NFZ4 NLGN2 PTHR43903:SF3 NEUROLIGIN NEUROLIGIN-2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular component biogenesis#GO:0044085;cellular localization#GO:0051641;synaptic vesicle cycle#GO:0099504;synaptic vesicle endocytosis#GO:0048488;membrane organization#GO:0061024;transport#GO:0006810;developmental process#GO:0032502;biological adhesion#GO:0022610;regulation of signaling#GO:0023051;nervous system development#GO:0007399;regulation of biological process#GO:0050789;system development#GO:0048731;chemical synaptic transmission#GO:0007268;membrane invagination#GO:0010324;establishment of localization#GO:0051234;anterograde trans-synaptic signaling#GO:0098916;synaptic signaling#GO:0099536;vesicle organization#GO:0016050;cell junction assembly#GO:0034329;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular component assembly#GO:0022607;endocytosis#GO:0006897;multicellular organism development#GO:0007275;trans-synaptic signaling#GO:0099537;cell-cell adhesion#GO:0098609;vesicle-mediated transport#GO:0016192;cell communication#GO:0007154;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;vesicle budding from membrane#GO:0006900;synapse assembly#GO:0007416;organelle organization#GO:0006996;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;modulation of chemical synaptic transmission#GO:0050804;cell junction organization#GO:0034330;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;multicellular organismal process#GO:0032501;vesicle-mediated transport in synapse#GO:0099003 cell surface#GO:0009986;synapse#GO:0045202;intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;cell junction#GO:0030054;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;integral component of membrane#GO:0016021;membrane#GO:0016020;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 HUMAN|HGNC=5253|UniProtKB=P07900 P07900 HSP90AA1 PTHR11528:SF87 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN HSP 90-ALPHA-RELATED carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;unfolded protein binding#GO:0051082;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;ATP binding#GO:0005524 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;regulation of biological quality#GO:0065008;response to heat#GO:0009408;protein folding#GO:0006457;cellular response to heat#GO:0034605;biological regulation#GO:0065007;regulation of protein stability#GO:0031647;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;cellular response to stress#GO:0033554;cellular process#GO:0009987;protein stabilization#GO:0050821 somatodendritic compartment#GO:0036477;perinuclear region of cytoplasm#GO:0048471;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;neuronal cell body#GO:0043025;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;cell surface#GO:0009986;cell body#GO:0044297;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 Hsp90 family chaperone#PC00028 HUMAN|HGNC=5977|UniProtKB=P40933 P40933 IL15 PTHR14356:SF3 INTERLEUKIN-15-RELATED INTERLEUKIN-15 receptor regulator activity#GO:0030545;binding#GO:0005488;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;molecular function regulator#GO:0098772;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102 positive regulation of gene expression#GO:0010628;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of cell-cell adhesion#GO:0022407;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of signal transduction#GO:0009967;positive regulation of cellular metabolic process#GO:0031325;gene expression#GO:0010467;positive regulation of cell population proliferation#GO:0008284;positive regulation of protein modification process#GO:0031401;cell population proliferation#GO:0008283;regulation of T cell activation#GO:0050863;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of cell activation#GO:0050865;regulation of biological process#GO:0050789;regulation of phosphorus metabolic process#GO:0051174;positive regulation of immune response#GO:0050778;peptidyl-tyrosine phosphorylation#GO:0018108;nitrogen compound metabolic process#GO:0006807;leukocyte proliferation#GO:0070661;regulation of signal transduction#GO:0009966;regulation of leukocyte cell-cell adhesion#GO:1903037;positive regulation of receptor signaling pathway via STAT#GO:1904894;positive regulation of cytokine production#GO:0001819;positive regulation of signaling#GO:0023056;cellular protein metabolic process#GO:0044267;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;mononuclear cell proliferation#GO:0032943;regulation of multicellular organismal process#GO:0051239;macromolecule metabolic process#GO:0043170;regulation of immune response#GO:0050776;positive regulation of phosphorus metabolic process#GO:0010562;cellular metabolic process#GO:0044237;cell communication#GO:0007154;cell adhesion#GO:0007155;positive regulation of macromolecule metabolic process#GO:0010604;tyrosine phosphorylation of STAT protein#GO:0007260;positive regulation of cellular process#GO:0048522;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;positive regulation of phosphate metabolic process#GO:0045937;regulation of protein phosphorylation#GO:0001932;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;multicellular organismal process#GO:0032501;positive regulation of cell activation#GO:0050867;regulation of phosphorylation#GO:0042325;regulation of metabolic process#GO:0019222;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;positive regulation of multicellular organismal process#GO:0051240;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;signal transduction#GO:0007165;regulation of phosphate metabolic process#GO:0019220;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;regulation of signaling#GO:0023051;biological adhesion#GO:0022610;protein modification process#GO:0036211;peptidyl-amino acid modification#GO:0018193;positive regulation of T cell proliferation#GO:0042102;regulation of receptor signaling pathway via STAT#GO:1904892;leukocyte cell-cell adhesion#GO:0007159;phosphorus metabolic process#GO:0006793;cytokine production#GO:0001816;phosphate-containing compound metabolic process#GO:0006796;positive regulation of response to stimulus#GO:0048584;T cell proliferation#GO:0042098;positive regulation of metabolic process#GO:0009893;positive regulation of leukocyte cell-cell adhesion#GO:1903039;regulation of immune system process#GO:0002682;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;protein metabolic process#GO:0019538;regulation of cell adhesion#GO:0030155;signaling#GO:0023052;regulation of lymphocyte activation#GO:0051249;metabolic process#GO:0008152;receptor signaling pathway via JAK-STAT#GO:0007259;regulation of cytokine production#GO:0001817;positive regulation of protein phosphorylation#GO:0001934;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of phosphorylation#GO:0042327;lymphocyte activation#GO:0046649;regulation of cell population proliferation#GO:0042127;immune response#GO:0006955;regulation of peptidyl-tyrosine phosphorylation#GO:0050730;positive regulation of peptidyl-tyrosine phosphorylation#GO:0050731;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;organonitrogen compound metabolic process#GO:1901564;protein phosphorylation#GO:0006468;lymphocyte proliferation#GO:0046651;cellular process#GO:0009987;regulation of T cell proliferation#GO:0042129;regulation of primary metabolic process#GO:0080090;positive regulation of tyrosine phosphorylation of STAT protein#GO:0042531;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of cellular protein metabolic process#GO:0032268;regulation of leukocyte activation#GO:0002694;positive regulation of protein metabolic process#GO:0051247;receptor signaling pathway via STAT#GO:0097696;regulation of mononuclear cell proliferation#GO:0032944;peptidyl-tyrosine modification#GO:0018212;regulation of macromolecule metabolic process#GO:0060255;positive regulation of receptor signaling pathway via JAK-STAT#GO:0046427;T cell activation#GO:0042110;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;regulation of lymphocyte proliferation#GO:0050670;positive regulation of T cell activation#GO:0050870;regulation of leukocyte proliferation#GO:0070663;positive regulation of cell adhesion#GO:0045785;positive regulation of cellular protein metabolic process#GO:0032270;positive regulation of cell-cell adhesion#GO:0022409 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 interleukin superfamily#PC00128 Interleukin signaling pathway#P00036>Interleukin#P00970;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IL2#P00870 HUMAN|HGNC=28577|UniProtKB=Q96NU7 Q96NU7 AMDHD1 PTHR42752:SF1 IMIDAZOLONEPROPIONASE IMIDAZOLONEPROPIONASE-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;oxoacid metabolic process#GO:0043436;heterocycle metabolic process#GO:0046483;heterocycle catabolic process#GO:0046700;organonitrogen compound metabolic process#GO:1901564;organonitrogen compound catabolic process#GO:1901565;cellular metabolic process#GO:0044237;cellular amino acid catabolic process#GO:0009063;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;primary metabolic process#GO:0044238;cellular nitrogen compound catabolic process#GO:0044270;organic acid catabolic process#GO:0016054;aromatic compound catabolic process#GO:0019439;small molecule catabolic process#GO:0044282;organic cyclic compound metabolic process#GO:1901360;aromatic amino acid family metabolic process#GO:0009072;nitrogen compound metabolic process#GO:0006807;alpha-amino acid metabolic process#GO:1901605;organic cyclic compound catabolic process#GO:1901361;catabolic process#GO:0009056;cellular amino acid metabolic process#GO:0006520;organic substance catabolic process#GO:1901575;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;aromatic amino acid family catabolic process#GO:0009074;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281 metalloprotease#PC00153 HUMAN|HGNC=13222|UniProtKB=Q9C0K0 Q9C0K0 BCL11B PTHR45993:SF4 B-CELL LYMPHOMA/LEUKEMIA 11 B-CELL LYMPHOMA/LEUKEMIA 11B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363 positive regulation of gene expression#GO:0010628;regulation of nitrogen compound metabolic process#GO:0051171;positive regulation of cellular metabolic process#GO:0031325;positive regulation of transcription by RNA polymerase II#GO:0045944;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;transcription, DNA-templated#GO:0006351;nitrogen compound metabolic process#GO:0006807;positive regulation of biological process#GO:0048518;organic substance metabolic process#GO:0071704;positive regulation of transcription, DNA-templated#GO:0045893;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular nitrogen compound metabolic process#GO:0034641;positive regulation of macromolecule metabolic process#GO:0010604;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;positive regulation of cellular process#GO:0048522;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular process#GO:0050794;aromatic compound biosynthetic process#GO:0019438;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;positive regulation of nitrogen compound metabolic process#GO:0051173;cellular aromatic compound metabolic process#GO:0006725;positive regulation of RNA biosynthetic process#GO:1902680;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;biosynthetic process#GO:0009058;positive regulation of biosynthetic process#GO:0009891;regulation of transcription, DNA-templated#GO:0006355;organic cyclic compound metabolic process#GO:1901360;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;positive regulation of nucleobase-containing compound metabolic process#GO:0045935;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;positive regulation of cellular biosynthetic process#GO:0031328;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of nucleic acid-templated transcription#GO:1903506;positive regulation of RNA metabolic process#GO:0051254;positive regulation of nucleic acid-templated transcription#GO:1903508;regulation of cellular macromolecule biosynthetic process#GO:2000112;transcription by RNA polymerase II#GO:0006366 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=6180|UniProtKB=Q14643 Q14643 ITPR1 PTHR13715:SF52 RYANODINE RECEPTOR AND IP3 RECEPTOR INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 1 calcium ion transmembrane transporter activity#GO:0015085;cation channel activity#GO:0005261;inorganic molecular entity transmembrane transporter activity#GO:0015318;calcium channel activity#GO:0005262;ion channel activity#GO:0005216;small molecule binding#GO:0036094;binding#GO:0005488;cation transmembrane transporter activity#GO:0008324;metal ion binding#GO:0046872;ion transmembrane transporter activity#GO:0015075;phospholipid binding#GO:0005543;transporter activity#GO:0005215;channel activity#GO:0015267;cation binding#GO:0043169;ligand-gated ion channel activity#GO:0015276;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;gated channel activity#GO:0022836;metal ion transmembrane transporter activity#GO:0046873;calcium ion binding#GO:0005509;lipid binding#GO:0008289;ion binding#GO:0043167;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;inorganic cation transmembrane transporter activity#GO:0022890;ligand-gated channel activity#GO:0022834 cellular metal ion homeostasis#GO:0006875;inorganic ion homeostasis#GO:0098771;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;calcium ion homeostasis#GO:0055074;divalent inorganic cation homeostasis#GO:0072507;regulation of sequestering of calcium ion#GO:0051282;inorganic cation transmembrane transport#GO:0098662;transport#GO:0006810;positive regulation of cytosolic calcium ion concentration#GO:0007204;cytosolic calcium ion transport#GO:0060401;regulation of localization#GO:0032879;inorganic ion transmembrane transport#GO:0098660;cation transport#GO:0006812;cellular homeostasis#GO:0019725;sequestering of calcium ion#GO:0051208;calcium ion transport#GO:0006816;cation transmembrane transport#GO:0098655;regulation of biological process#GO:0050789;divalent metal ion transport#GO:0070838;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;ion homeostasis#GO:0050801;cellular calcium ion homeostasis#GO:0006874;divalent inorganic cation transport#GO:0072511;cellular divalent inorganic cation homeostasis#GO:0072503;negative regulation of cellular process#GO:0048523;cellular cation homeostasis#GO:0030003;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;calcium ion transmembrane transport#GO:0070588;ion transport#GO:0006811;release of sequestered calcium ion into cytosol#GO:0051209;homeostatic process#GO:0042592;cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular process#GO:0009987;regulation of cytosolic calcium ion concentration#GO:0051480;regulation of cellular localization#GO:0060341;ion transmembrane transport#GO:0034220;cellular ion homeostasis#GO:0006873;localization#GO:0051179;cellular chemical homeostasis#GO:0055082;calcium ion transport into cytosol#GO:0060402;maintenance of location#GO:0051235;regulation of cellular process#GO:0050794;maintenance of location in cell#GO:0051651;calcium ion transmembrane import into cytosol#GO:0097553;biological regulation#GO:0065007;establishment of localization in cell#GO:0051649;metal ion homeostasis#GO:0055065;negative regulation of sequestering of calcium ion#GO:0051283 bounding membrane of organelle#GO:0098588;sarcoplasmic reticulum#GO:0016529;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;secretory granule membrane#GO:0030667;secretory granule#GO:0030141;sarcoplasm#GO:0016528;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;vesicle membrane#GO:0012506;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle membrane#GO:0030659;endoplasmic reticulum#GO:0005783;secretory vesicle#GO:0099503;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 T cell activation#P00053>IP3R#P01331;Histamine H1 receptor mediated signaling pathway#P04385>IP3R#P04486;Endothelin signaling pathway#P00019>IP3 R#P00590;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>IP3R#P01064;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>IP3R#P00842;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>IP3 channel#P00735;Alpha adrenergic receptor signaling pathway#P00002>IP3R#P00076;CCKR signaling map#P06959>IP3R#P07123;Gonadotropin-releasing hormone receptor pathway#P06664>IP3R#P06768;B cell activation#P00010>IP3R#P00398;Wnt signaling pathway#P00057>IP3 Gated Calcium Channel#P01426;Metabotropic glutamate receptor group I pathway#P00041>IP3R#P01056;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>IP3R#P05932;PDGF signaling pathway#P00047>IP3 receptor#P01160 HUMAN|HGNC=27271|UniProtKB=P0CG24 P0CG24 ZNF883 PTHR23226:SF255 ZINC FINGER AND SCAN DOMAIN-CONTAINING ZINC FINGER PROTEIN 883 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 C2H2 zinc finger transcription factor#PC00248 HUMAN|HGNC=12309|UniProtKB=Q15649 Q15649 ZNHIT3 PTHR13483:SF11 UNCHARACTERIZED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;RNA localization#GO:0006403;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;maturation of LSU-rRNA#GO:0000470 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=12106|UniProtKB=A0A075B6T6 A0A075B6T6 TRAV12-2 PTHR19343:SF3 T CELL RECEPTOR ALPHA VARIABLE 1-2 T CELL RECEPTOR ALPHA VARIABLE 12-2 HUMAN|HGNC=10418|UniProtKB=P62857 P62857 RPS28 PTHR10769:SF3 40S RIBOSOMAL PROTEIN S28 40S RIBOSOMAL PROTEIN S28 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribonucleoprotein complex subunit organization#GO:0071826;RNA processing#GO:0006396;protein-containing complex assembly#GO:0065003;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribonucleoprotein complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;protein-containing complex subunit organization#GO:0043933;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;heterocycle metabolic process#GO:0046483;cellular component assembly#GO:0022607;cellular protein-containing complex assembly#GO:0034622;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;rRNA metabolic process#GO:0016072;organelle organization#GO:0006996;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA#GO:0030490;ribosomal small subunit biogenesis#GO:0042274 intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;non-membrane-bounded organelle#GO:0043228;cytosolic ribosome#GO:0022626;protein-containing complex#GO:0032991;cytosolic small ribosomal subunit#GO:0022627;intracellular#GO:0005622;cytosol#GO:0005829;small ribosomal subunit#GO:0015935;cellular anatomical entity#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229;ribosomal subunit#GO:0044391 ribosomal protein#PC00202 HUMAN|HGNC=30887|UniProtKB=Q9UL33 Q9UL33 TRAPPC2L PTHR12403:SF23 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-LIKE PROTEIN localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;vesicle tethering complex#GO:0099023;TRAPP complex#GO:0030008;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 HUMAN|HGNC=24331|UniProtKB=Q5VYJ5 Q5VYJ5 MALRD1 PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM AND LDL-RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 1 HUMAN|HGNC=14885|UniProtKB=Q8WW22 Q8WW22 DNAJA4 PTHR43888:SF9 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 4 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 chaperone#PC00072 HUMAN|HGNC=6904|UniProtKB=P31153 P31153 MAT2A PTHR11964:SF1 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 nucleotidyltransferase#PC00174 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 HUMAN|HGNC=23703|UniProtKB=Q7Z2K6 Q7Z2K6 ERMP1 PTHR12147:SF50 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704 metalloprotease#PC00153 HUMAN|HGNC=31969|UniProtKB=Q5MNV8 Q5MNV8 FBXO47 PTHR34098:SF1 F-BOX ONLY PROTEIN 47 F-BOX ONLY PROTEIN 47 HUMAN|HGNC=1730|UniProtKB=Q9UQ88 Q9UQ88 CDK11A PTHR24056:SF107 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 11A-RELATED cyclin-dependent protein kinase activity#GO:0097472;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;binding#GO:0005488;catalytic activity#GO:0003824;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein serine/threonine kinase activity#GO:0004674;protein binding#GO:0005515;cyclin binding#GO:0030332;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 macromolecule modification#GO:0043412;nuclear division#GO:0000280;cellular macromolecule metabolic process#GO:0044260;cell cycle process#GO:0022402;protein modification process#GO:0036211;gene expression#GO:0010467;mitotic cell cycle process#GO:1903047;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;nitrogen compound metabolic process#GO:0006807;mitotic nuclear division#GO:0140014;phosphorylation#GO:0016310;regulation of gene expression#GO:0010468;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;protein phosphorylation#GO:0006468;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;cellular component organization or biogenesis#GO:0071840;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;cell cycle#GO:0007049;organelle fission#GO:0048285;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle#GO:0007346;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=2034|UniProtKB=P56749 P56749 CLDN12 PTHR16703:SF3 CLAUDIN-12 CLAUDIN-12 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=1426|UniProtKB=Q9ULU8 Q9ULU8 CADPS PTHR12166:SF6 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR 1 vesicle fusion#GO:0006906;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;transport#GO:0006810;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of transport#GO:0051049;establishment of localization#GO:0051234;positive regulation of exocytosis#GO:0045921;regulation of secretion#GO:0051046;secretion#GO:0046903;vesicle organization#GO:0016050;positive regulation of biological process#GO:0048518;regulation of exocytosis#GO:0017157;secretion by cell#GO:0032940;organelle fusion#GO:0048284;vesicle fusion to plasma membrane#GO:0099500;positive regulation of secretion#GO:0051047;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;cellular component organization#GO:0016043;cellular process#GO:0009987;exocytic process#GO:0140029;positive regulation of cellular process#GO:0048522;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;membrane fusion#GO:0061025;exocytosis#GO:0006887;regulation of cellular process#GO:0050794;organelle organization#GO:0006996;biological regulation#GO:0065007;positive regulation of secretion by cell#GO:1903532;export from cell#GO:0140352 cell junction#GO:0030054;glutamatergic synapse#GO:0098978;synapse#GO:0045202;cellular anatomical entity#GO:0110165 membrane trafficking regulatory protein#PC00151 HUMAN|HGNC=7578|UniProtKB=P13535 P13535 MYH8 PTHR45615:SF35 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN-8 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 HUMAN|HGNC=7114|UniProtKB=Q13064 Q13064 MKRN3 PTHR11224:SF38 MAKORIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE MAKORIN-3-RELATED ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;cellular metabolic process#GO:0044237;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=6819|UniProtKB=Q9UDY8 Q9UDY8 MALT1 PTHR22576:SF40 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 cysteine protease#PC00081 HUMAN|HGNC=51901|UniProtKB=A0A140G945 A0A140G945 CRYAA2 PTHR45640:SF14 HEAT SHOCK PROTEIN HSP-12.2-RELATED ALPHA-CRYSTALLIN A CHAIN-RELATED VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 HUMAN|HGNC=2633|UniProtKB=Q6ZSU1 Q6ZSU1 CYP2G1P PTHR24300:SF340 CYTOCHROME P450 508A4-RELATED INACTIVE CYTOCHROME P450 2G1-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;heme binding#GO:0020037 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;oxidation-reduction process#GO:0055114;catabolic process#GO:0009056;cellular metabolic process#GO:0044237;cellular process#GO:0009987;organic acid metabolic process#GO:0006082;cellular catabolic process#GO:0044248;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177 HUMAN|HGNC=1720|UniProtKB=Q13042 Q13042 CDC16 PTHR12558:SF9 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 16 HOMOLOG ubiquitin-protein ligase#PC00234 HUMAN|HGNC=7692|UniProtKB=P51970 P51970 NDUFA8 PTHR13344:SF0 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8 envelope#GO:0031975;mitochondrial protein complex#GO:0098798;membrane protein complex#GO:0098796;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial inner membrane#GO:0005743;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;membrane#GO:0016020;organelle envelope#GO:0031967;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;respirasome#GO:0070469;mitochondrial respiratory chain complex I#GO:0005747;protein-containing complex#GO:0032991;intracellular#GO:0005622;mitochondrial envelope#GO:0005740;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial respirasome#GO:0005746;membrane-bounded organelle#GO:0043227;respiratory chain complex I#GO:0045271;NADH dehydrogenase complex#GO:0030964 oxidoreductase#PC00176 HUMAN|HGNC=18054|UniProtKB=Q96T91 Q96T91 GPHA2 PTHR31129:SF2 GLYCOPROTEIN HORMONE ALPHA-2 GLYCOPROTEIN HORMONE ALPHA-2 protein binding#GO:0005515;binding#GO:0005488;hormone receptor binding#GO:0051427;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;response to stimulus#GO:0050896;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell communication#GO:0007154;cellular process#GO:0009987;signaling#GO:0023052 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 peptide hormone#PC00179 HUMAN|HGNC=9579|UniProtKB=O60542 O60542 PSPN PTHR12173:SF8 GDNF SUBFAMILY OF TGF-BETA FAMILY PERSEPHIN binding#GO:0005488;receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;signaling receptor activator activity#GO:0030546;receptor ligand activity#GO:0048018;protein binding#GO:0005515;molecular function regulator#GO:0098772;signaling receptor binding#GO:0005102 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 neurotrophic factor#PC00163 HUMAN|HGNC=24447|UniProtKB=Q9NRP2 Q9NRP2 CMC2 PTHR22977:SF1 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN 2 HOMOLOG cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=9912|UniProtKB=P0DJD3 P0DJD3 RBMY1A1 PTHR23147:SF65 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING MOTIF PROTEIN, Y CHROMOSOME, FAMILY 1 MEMBER A1-RELATED nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;RNA metabolic process#GO:0016070;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;mRNA cis splicing, via spliceosome#GO:0045292;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;alternative mRNA splicing, via spliceosome#GO:0000380;regulation of mRNA processing#GO:0050684;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;mRNA splicing, via spliceosome#GO:0000398;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;biological regulation#GO:0065007;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA metabolic process#GO:1903311;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;nuclear speck#GO:0016607;organelle#GO:0043226;nuclear body#GO:0016604;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=18621|UniProtKB=Q9Y2V7 Q9Y2V7 COG6 PTHR21506:SF0 COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6 localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;intra-Golgi vesicle-mediated transport#GO:0006891;transport#GO:0006810 intracellular membrane-bounded organelle#GO:0043231;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;vacuole#GO:0005773;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi transport complex#GO:0017119;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane#GO:0005886 HUMAN|HGNC=31796|UniProtKB=Q5QJ38 Q5QJ38 TCHHL1 PTHR47612:SF1 TRICHOHYALIN-LIKE PROTEIN 1 TRICHOHYALIN-LIKE PROTEIN 1 HUMAN|HGNC=27977|UniProtKB=A4D161 A4D161 FAM221A PTHR31214:SF2 PROTEIN FAM221A-RELATED PROTEIN FAM221A HUMAN|HGNC=29515|UniProtKB=Q9H7P9 Q9H7P9 PLEKHG2 PTHR45924:SF3 FI17866P1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 2 Rho guanyl-nucleotide exchange factor activity#GO:0005089;Ras GTPase binding#GO:0017016;binding#GO:0005488;GTPase binding#GO:0051020;Ras guanyl-nucleotide exchange factor activity#GO:0005088;enzyme binding#GO:0019899;protein binding#GO:0005515;molecular function regulator#GO:0098772;small GTPase binding#GO:0031267;Rho GTPase binding#GO:0017048;guanyl-nucleotide exchange factor activity#GO:0005085 HUMAN|HGNC=28484|UniProtKB=Q86W50 Q86W50 METTL16 PTHR13393:SF0 SAM-DEPENDENT METHYLTRANSFERASE RNA N6-ADENOSINE-METHYLTRANSFERASE METTL16 catalytic activity, acting on RNA#GO:0140098;N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173 cellular aromatic compound metabolic process#GO:0006725;cellular component biogenesis#GO:0044085;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;rRNA modification#GO:0000154;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;ncRNA metabolic process#GO:0034660;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;ribosome biogenesis#GO:0042254;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;macromolecule methylation#GO:0043414;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;rRNA base methylation#GO:0070475;RNA methylation#GO:0001510 methyltransferase#PC00155 HUMAN|HGNC=16902|UniProtKB=O14874 O14874 BCKDK PTHR11947:SF20 PYRUVATE DEHYDROGENASE KINASE [3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, MITOCHONDRIAL transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;protein serine/threonine kinase activity#GO:0004674;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;biological regulation#GO:0065007;oxidation-reduction process#GO:0055114;glucose homeostasis#GO:0042593;homeostatic process#GO:0042592;negative regulation of metabolic process#GO:0009892;regulation of catalytic activity#GO:0050790;chemical homeostasis#GO:0048878;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;negative regulation of molecular function#GO:0044092;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;mitochondrion#GO:0005739;organelle#GO:0043226;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 HUMAN|HGNC=2869|UniProtKB=P49366 P49366 DHPS PTHR11703:SF0 DEOXYHYPUSINE SYNTHASE DEOXYHYPUSINE SYNTHASE transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 peptidyl-lysine modification#GO:0018205;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;organonitrogen compound metabolic process#GO:1901564;protein modification process#GO:0036211;protein maturation#GO:0051604;gene expression#GO:0010467;cellular metabolic process#GO:0044237;peptidyl-amino acid modification#GO:0018193;biosynthetic process#GO:0009058;cellular process#GO:0009987;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;nitrogen compound metabolic process#GO:0006807;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=19261|UniProtKB=Q9Y2Z2 Q9Y2Z2 MTO1 PTHR11806:SF0 GLUCOSE INHIBITED DIVISION PROTEIN A PROTEIN MTO1 HOMOLOG, MITOCHONDRIAL nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;organic cyclic compound binding#GO:0097159;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;ion binding#GO:0043167 cellular aromatic compound metabolic process#GO:0006725;tRNA metabolic process#GO:0006399;heterocycle metabolic process#GO:0046483;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular macromolecule metabolic process#GO:0044260;RNA modification#GO:0009451;tRNA processing#GO:0008033;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;ncRNA metabolic process#GO:0034660;nucleic acid metabolic process#GO:0090304;macromolecule methylation#GO:0043414;tRNA methylation#GO:0030488;methylation#GO:0032259;organic cyclic compound metabolic process#GO:1901360;ncRNA processing#GO:0034470;nitrogen compound metabolic process#GO:0006807;RNA methylation#GO:0001510;tRNA wobble uridine modification#GO:0002098;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 HUMAN|HGNC=8656|UniProtKB=Q9BZA7 Q9BZA7 PCDH11X PTHR24028:SF254 CADHERIN-87A PROTOCADHERIN-11 X-LINKED-RELATED cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=18003|UniProtKB=Q7RTU3 Q7RTU3 OLIG3 PTHR19290:SF96 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED OLIGODENDROCYTE TRANSCRIPTION FACTOR 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;neurogenesis#GO:0022008;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;neuron differentiation#GO:0030182;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;multicellular organism development#GO:0007275;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;multicellular organismal process#GO:0032501;regulation of nucleic acid-templated transcription#GO:1903506;generation of neurons#GO:0048699;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular#GO:0005622 basic helix-loop-helix transcription factor#PC00055 HUMAN|HGNC=2375|UniProtKB=Q9NVC6 Q9NVC6 MED17 PTHR13114:SF7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 molecular function regulator#GO:0098772;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;intracellular#GO:0005622;core mediator complex#GO:0070847;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 general transcription factor#PC00259 HUMAN|HGNC=17410|UniProtKB=Q9GZV7 Q9GZV7 HAPLN2 PTHR22804:SF8 AGGRECAN/VERSICAN PROTEOGLYCAN HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 2 extracellular matrix glycoprotein#PC00100 HUMAN|HGNC=2214|UniProtKB=Q02388 Q02388 COL7A1 PTHR24020:SF4 COLLAGEN ALPHA COLLAGEN ALPHA-1(VII) CHAIN-RELATED extracellular matrix#GO:0031012;collagen-containing extracellular matrix#GO:0062023;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103 HUMAN|HGNC=14343|UniProtKB=Q9BXI9 Q9BXI9 C1QTNF6 PTHR22923:SF70 CEREBELLIN-RELATED COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 6 HUMAN|HGNC=24166|UniProtKB=Q96KN1 Q96KN1 LRATD2 PTHR46341:SF2 PROTEIN FAM84B-RELATED PROTEIN LRATD2 HUMAN|HGNC=30702|UniProtKB=Q9NP50 Q9NP50 SINHCAF PTHR13422:SF18 UNCHARACTERIZED SIN3-HDAC COMPLEX-ASSOCIATED FACTOR regulation of cellular component movement#GO:0051270;negative regulation of locomotion#GO:0040013;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;regulation of locomotion#GO:0040012;localization of cell#GO:0051674;regulation of localization#GO:0032879;cell motility#GO:0048870;cellular process#GO:0009987;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell migration#GO:0030334;negative regulation of cellular component movement#GO:0051271;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;movement of cell or subcellular component#GO:0006928;negative regulation of cell motility#GO:2000146;cell migration#GO:0016477;locomotion#GO:0040011;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;nucleoplasm#GO:0005654;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular#GO:0005622;chromosome#GO:0005694;histone deacetylase complex#GO:0000118;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 HUMAN|HGNC=25031|UniProtKB=Q6NWY9 Q6NWY9 PRPF40B PTHR11864:SF1 PRE-MRNA-PROCESSING PROTEIN PRP40 PRE-MRNA-PROCESSING FACTOR 40 HOMOLOG B nucleic acid binding#GO:0003676;RNA binding#GO:0003723;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions#GO:0000375;mRNA splicing, via spliceosome#GO:0000398;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;U1 snRNP#GO:0005685;U2-type spliceosomal complex#GO:0005684;cellular anatomical entity#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;spliceosomal snRNP complex#GO:0097525;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U2-type prespliceosome#GO:0071004;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114 HUMAN|HGNC=5606|UniProtKB=P01763 P01763 IGHV3-48 PTHR23266:SF357 IMMUNOGLOBULIN HEAVY CHAIN IMMUNOGLOBULIN HEAVY VARIABLE 3-11-RELATED protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 response to external biotic stimulus#GO:0043207;immune response-regulating signaling pathway#GO:0002764;antigen receptor-mediated signaling pathway#GO:0050851;activation of immune response#GO:0002253;membrane organization#GO:0061024;B cell receptor signaling pathway#GO:0050853;lymphocyte mediated immunity#GO:0002449;positive regulation of lymphocyte activation#GO:0051251;positive regulation of leukocyte activation#GO:0002696;regulation of biological process#GO:0050789;regulation of cell activation#GO:0050865;positive regulation of immune response#GO:0050778;protein activation cascade#GO:0072376;response to biotic stimulus#GO:0009607;membrane invagination#GO:0010324;establishment of localization#GO:0051234;nitrogen compound metabolic process#GO:0006807;immune response-activating signal transduction#GO:0002757;innate immune response#GO:0045087;B cell activation#GO:0042113;defense response#GO:0006952;positive regulation of biological process#GO:0048518;leukocyte activation#GO:0045321;organic substance metabolic process#GO:0071704;immune response-regulating cell surface receptor signaling pathway#GO:0002768;phagocytosis#GO:0006909;macromolecule metabolic process#GO:0043170;interspecies interaction between organisms#GO:0044419;endocytosis#GO:0006897;regulation of immune response#GO:0050776;vesicle-mediated transport#GO:0016192;cellular component organization#GO:0016043;cell communication#GO:0007154;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains#GO:0002460;primary metabolic process#GO:0044238;positive regulation of cellular process#GO:0048522;cell activation#GO:0001775;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of cellular process#GO:0050794;positive regulation of cell activation#GO:0050867;immune response-activating cell surface receptor signaling pathway#GO:0002429;complement activation#GO:0006956;cell recognition#GO:0008037;signal transduction#GO:0007165;humoral immune response#GO:0006959;transport#GO:0006810;positive regulation of response to stimulus#GO:0048584;adaptive immune response#GO:0002250;response to bacterium#GO:0009617;regulation of immune system process#GO:0002682;vesicle organization#GO:0016050;protein metabolic process#GO:0019538;regulation of lymphocyte activation#GO:0051249;signaling#GO:0023052;immune effector process#GO:0002252;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;lymphocyte activation#GO:0046649;immune response#GO:0006955;leukocyte mediated immunity#GO:0002443;organonitrogen compound metabolic process#GO:1901564;positive regulation of immune system process#GO:0002684;cellular process#GO:0009987;localization#GO:0051179;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;regulation of leukocyte activation#GO:0002694;vesicle budding from membrane#GO:0006900;organelle organization#GO:0006996;response to other organism#GO:0051707;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007 external side of plasma membrane#GO:0009897;cell surface#GO:0009986;leaflet of membrane bilayer#GO:0097478;protein-containing complex#GO:0032991;extracellular region#GO:0005576;cell periphery#GO:0071944;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;membrane#GO:0016020;side of membrane#GO:0098552;plasma membrane#GO:0005886 immunoglobulin#PC00123 HUMAN|HGNC=15520|UniProtKB=P43657 P43657 LPAR6 PTHR24232:SF3 G-PROTEIN COUPLED RECEPTOR LYSOPHOSPHATIDIC ACID RECEPTOR 6 carbohydrate derivative binding#GO:0097367;signaling receptor activity#GO:0038023;binding#GO:0005488;molecular transducer activity#GO:0060089;lipid binding#GO:0008289;anion binding#GO:0043168;G protein-coupled receptor activity#GO:0004930;ion binding#GO:0043167;phospholipid binding#GO:0005543;transmembrane signaling receptor activity#GO:0004888 inorganic ion homeostasis#GO:0098771;divalent inorganic cation homeostasis#GO:0072507;positive regulation of signal transduction#GO:0009967;positive regulation of cytosolic calcium ion concentration#GO:0007204;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;regulation of biological process#GO:0050789;cellular calcium ion homeostasis#GO:0006874;regulation of biological quality#GO:0065008;regulation of molecular function#GO:0065009;regulation of signal transduction#GO:0009966;activation of phospholipase C activity#GO:0007202;regulation of hydrolase activity#GO:0051336;intracellular signal transduction#GO:0035556;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of phospholipase C activity#GO:0010863;regulation of Rho protein signal transduction#GO:0035023;cellular cation homeostasis#GO:0030003;regulation of phospholipase C activity#GO:1900274;inositol phosphate-mediated signaling#GO:0048016;cell communication#GO:0007154;cation homeostasis#GO:0055080;regulation of cytosolic calcium ion concentration#GO:0051480;cellular ion homeostasis#GO:0006873;positive regulation of hydrolase activity#GO:0051345;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of cellular process#GO:0048522;small GTPase mediated signal transduction#GO:0007264;regulation of response to stimulus#GO:0048583;positive regulation of Ras protein signal transduction#GO:0046579;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;G protein-coupled receptor signaling pathway#GO:0007186;metal ion homeostasis#GO:0055065;regulation of Ras protein signal transduction#GO:0046578;positive regulation of lipase activity#GO:0060193;cellular metal ion homeostasis#GO:0006875;signal transduction#GO:0007165;calcium ion homeostasis#GO:0055074;second-messenger-mediated signaling#GO:0019932;regulation of lipase activity#GO:0060191;regulation of signaling#GO:0023051;positive regulation of molecular function#GO:0044093;regulation of phospholipase activity#GO:0010517;cellular homeostasis#GO:0019725;regulation of catalytic activity#GO:0050790;positive regulation of response to stimulus#GO:0048584;ion homeostasis#GO:0050801;cellular divalent inorganic cation homeostasis#GO:0072503;positive regulation of intracellular signal transduction#GO:1902533;signaling#GO:0023052;regulation of cell communication#GO:0010646;cellular response to stimulus#GO:0051716;positive regulation of catalytic activity#GO:0043085;positive regulation of phospholipase activity#GO:0010518;homeostatic process#GO:0042592;cellular process#GO:0009987;chemical homeostasis#GO:0048878;Rho protein signal transduction#GO:0007266;cellular chemical homeostasis#GO:0055082;response to stimulus#GO:0050896;biological regulation#GO:0065007 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 HUMAN|HGNC=2953|UniProtKB=Q9NYC9 Q9NYC9 DNAH9 PTHR10676:SF257 DYNEIN HEAVY CHAIN FAMILY PROTEIN DYNEIN HEAVY CHAIN 9, AXONEMAL pyrophosphatase activity#GO:0016462;microtubule motor activity#GO:0003777;motor activity#GO:0003774;binding#GO:0005488;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;nucleoside-triphosphatase activity#GO:0017111;ATPase activity#GO:0016887 movement of cell or subcellular component#GO:0006928;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987;cilium movement#GO:0003341 supramolecular complex#GO:0099080;axoneme#GO:0005930;catalytic complex#GO:1902494;cytoplasmic region#GO:0099568;supramolecular polymer#GO:0099081;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;supramolecular fiber#GO:0099512;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;intracellular non-membrane-bounded organelle#GO:0043232;cytoplasm#GO:0005737;microtubule associated complex#GO:0005875;non-membrane-bounded organelle#GO:0043228;motile cilium#GO:0031514;protein-containing complex#GO:0032991;intracellular#GO:0005622;microtubule cytoskeleton#GO:0015630;ciliary plasm#GO:0097014;plasma membrane bounded cell projection cytoplasm#GO:0032838;plasma membrane region#GO:0098590;dynein complex#GO:0030286;cell projection#GO:0042995;cytoskeleton#GO:0005856;cilium#GO:0005929;microtubule#GO:0005874;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 microtubule binding motor protein#PC00156 HUMAN|HGNC=3799|UniProtKB=Q99853 Q99853 FOXB1 PTHR11829:SF209 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN B1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular function regulator#GO:0098772;heterocyclic compound binding#GO:1901363;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;cell differentiation#GO:0030154;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;anatomical structure morphogenesis#GO:0009653;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular developmental process#GO:0048869;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;anatomical structure development#GO:0048856;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 winged helix/forkhead transcription factor#PC00246 HUMAN|HGNC=18432|UniProtKB=Q96PC5 Q96PC5 MIA2 PTHR23158:SF38 MELANOMA INHIBITORY ACTIVITY-RELATED MELANOMA INHIBITORY ACTIVITY PROTEIN 2 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;macromolecule localization#GO:0033036;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;protein secretion#GO:0009306;peptide secretion#GO:0002790;peptide transport#GO:0015833;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;establishment of protein localization to extracellular region#GO:0035592;organic substance transport#GO:0071702;establishment of localization#GO:0051234;secretion#GO:0046903;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940 endoplasmic reticulum exit site#GO:0070971;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;vacuole#GO:0005773;organelle membrane#GO:0031090;cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=8297|UniProtKB=Q8NGC2 Q8NGC2 OR4E2 PTHR26451:SF160 G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN OLFACTORY RECEPTOR 4E2 HUMAN|HGNC=31421|UniProtKB=Q5VZ72 Q5VZ72 IZUMO3 PTHR36470:SF1 IZUMO SPERM-EGG FUSION PROTEIN 3 IZUMO SPERM-EGG FUSION PROTEIN 3 HUMAN|HGNC=8786|UniProtKB=P35913 P35913 PDE6B PTHR11347:SF73 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT BETA hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric diester hydrolase activity#GO:0008081;3',5'-cyclic-nucleotide phosphodiesterase activity#GO:0004114;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;animal organ development#GO:0048513;developmental process#GO:0032502;multicellular organism development#GO:0007275;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;system development#GO:0048731;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;retina development in camera-type eye#GO:0060041;eye development#GO:0001654;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;camera-type eye development#GO:0043010;sensory system development#GO:0048880;visual system development#GO:0150063;sensory organ development#GO:0007423;signaling#GO:0023052 bounding membrane of organelle#GO:0098588;9+0 non-motile cilium#GO:0097731;non-motile cilium#GO:0097730;ciliary membrane#GO:0060170;organelle membrane#GO:0031090;cell projection membrane#GO:0031253;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;protein-containing complex#GO:0032991;neuron projection#GO:0043005;photoreceptor outer segment#GO:0001750;plasma membrane region#GO:0098590;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929;intraciliary transport particle#GO:0030990;plasma membrane#GO:0005886 phosphodiesterase#PC00185 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PDEalphabeta#P00759 HUMAN|HGNC=9092|UniProtKB=O15162 O15162 PLSCR1 PTHR23248:SF38 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE 1 phospholipid transporter activity#GO:0005548;transporter activity#GO:0005215;lipid transporter activity#GO:0005319 organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;membrane organization#GO:0061024;organic anion transport#GO:0015711;plasma membrane organization#GO:0007009;ion transport#GO:0006811;transport#GO:0006810;plasma membrane phospholipid scrambling#GO:0017121;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;phospholipid transport#GO:0015914;cellular process#GO:0009987;lipid transport#GO:0006869;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organic substance transport#GO:0071702;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;anion transport#GO:0006820;biological regulation#GO:0065007;lipid translocation#GO:0034204;lipid localization#GO:0010876;phospholipid translocation#GO:0045332 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transporter#PC00227 HUMAN|HGNC=4912|UniProtKB=P49773 P49773 HINT1 PTHR23089:SF45 HISTIDINE TRIAD HIT PROTEIN HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular aromatic compound metabolic process#GO:0006725;carbohydrate derivative metabolic process#GO:1901135;heterocycle catabolic process#GO:0046700;organonitrogen compound catabolic process#GO:1901565;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;cellular nitrogen compound catabolic process#GO:0044270;phosphate-containing compound metabolic process#GO:0006796;organic cyclic compound metabolic process#GO:1901360;ribose phosphate metabolic process#GO:0019693;nitrogen compound metabolic process#GO:0006807;nucleobase-containing small molecule biosynthetic process#GO:0034404;cellular nitrogen compound biosynthetic process#GO:0044271;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound metabolic process#GO:0072521;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;purine nucleotide metabolic process#GO:0006163;cellular catabolic process#GO:0044248;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;nucleotide catabolic process#GO:0009166;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide metabolic process#GO:0009150;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;heterocycle biosynthetic process#GO:0018130;aromatic compound catabolic process#GO:0019439;nucleobase-containing compound biosynthetic process#GO:0034654;organic cyclic compound catabolic process#GO:1901361;aromatic compound biosynthetic process#GO:0019438;organophosphate metabolic process#GO:0019637;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound catabolic process#GO:0034655;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 nucleotide phosphatase#PC00173 HUMAN|HGNC=14065|UniProtKB=Q9UKV0 Q9UKV0 HDAC9 PTHR48252:SF1 HISTONE DEACETYLASE 2-RELATED HISTONE DEACETYLASE 9 HUMAN|HGNC=5884|UniProtKB=A0A075B6I4 A0A075B6I4 IGLV10-54 PTHR23267:SF225 IMMUNOGLOBULIN LIGHT CHAIN IMMUNOGLOBULIN LAMBDA VARIABLE 10-54 response to stimulus#GO:0050896;immune system process#GO:0002376;immunoglobulin production#GO:0002377;immune response#GO:0006955;production of molecular mediator of immune response#GO:0002440 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 immunoglobulin#PC00123 HUMAN|HGNC=20406|UniProtKB=P48668 P48668 KRT6C PTHR45616:SF47 FAMILY NOT NAMED KERATIN, TYPE II CYTOSKELETAL 6C HUMAN|HGNC=25966|UniProtKB=Q6NXG1 Q6NXG1 ESRP1 PTHR13976:SF37 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED EPITHELIAL SPLICING REGULATORY PROTEIN 1 nucleic acid binding#GO:0003676;RNA binding#GO:0003723;mRNA binding#GO:0003729;heterocyclic compound binding#GO:1901363;binding#GO:0005488;organic cyclic compound binding#GO:0097159 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;regulation of nitrogen compound metabolic process#GO:0051171;RNA processing#GO:0006396;gene expression#GO:0010467;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;RNA splicing#GO:0008380;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;nucleic acid metabolic process#GO:0090304;organic cyclic compound metabolic process#GO:1901360;regulation of macromolecule metabolic process#GO:0060255;nitrogen compound metabolic process#GO:0006807;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 HUMAN|HGNC=8682|UniProtKB=Q9Y5F2 Q9Y5F2 PCDHB11 PTHR24028:SF286 CADHERIN-87A PROTOCADHERIN BETA-11 cell adhesion#GO:0007155;cellular process#GO:0009987;biological adhesion#GO:0022610 intrinsic component of membrane#GO:0031224;integral component of plasma membrane#GO:0005887;intrinsic component of plasma membrane#GO:0031226;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;integral component of membrane#GO:0016021;plasma membrane#GO:0005886 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 HUMAN|HGNC=26858|UniProtKB=Q2M2D7 Q2M2D7 TBC1D28 PTHR22957:SF598 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 26-RELATED GTPase activity#GO:0003924;binding#GO:0005488;catalytic activity#GO:0003824;GTPase binding#GO:0051020;enzyme binding#GO:0019899;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;Rab GTPase binding#GO:0017137;nucleoside-triphosphatase regulator activity#GO:0060589;pyrophosphatase activity#GO:0016462;GTPase regulator activity#GO:0030695;Ras GTPase binding#GO:0017016;GTPase activator activity#GO:0005096;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator#GO:0098772;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside-triphosphatase activity#GO:0017111 cellular localization#GO:0051641;macromolecule localization#GO:0033036;regulation of GTPase activity#GO:0043087;positive regulation of catalytic activity#GO:0043085;positive regulation of GTPase activity#GO:0043547;cellular protein localization#GO:0034613;transport#GO:0006810;positive regulation of molecular function#GO:0044093;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;regulation of catalytic activity#GO:0050790;cellular process#GO:0009987;establishment of protein localization#GO:0045184;positive regulation of hydrolase activity#GO:0051345;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;cellular macromolecule localization#GO:0070727;establishment of localization#GO:0051234;regulation of molecular function#GO:0065009;protein transport#GO:0015031;biological regulation#GO:0065007;regulation of hydrolase activity#GO:0051336;intracellular protein transport#GO:0006886;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 GTPase-activating protein#PC00257 HUMAN|HGNC=13582|UniProtKB=Q9UK99 Q9UK99 FBXO3 PTHR46550:SF1 F-BOX ONLY PROTEIN 3 F-BOX ONLY PROTEIN 3 HUMAN|HGNC=33519|UniProtKB=P0C7M4 P0C7M4 RHOXF2B PTHR24329:SF540 HOMEOBOX PROTEIN ARISTALESS RHOX HOMEOBOX FAMILY MEMBER 2-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription regulatory region sequence-specific DNA binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;molecular function regulator#GO:0098772;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular aromatic compound metabolic process#GO:0006725;regulation of nitrogen compound metabolic process#GO:0051171;RNA metabolic process#GO:0016070;cellular macromolecule metabolic process#GO:0044260;regulation of transcription by RNA polymerase II#GO:0006357;gene expression#GO:0010467;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biological process#GO:0050789;regulation of transcription, DNA-templated#GO:0006355;transcription, DNA-templated#GO:0006351;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;regulation of biosynthetic process#GO:0009889;cellular nitrogen compound biosynthetic process#GO:0044271;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleic acid-templated transcription#GO:0097659;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;RNA biosynthetic process#GO:0032774;cellular biosynthetic process#GO:0044249;organic substance biosynthetic process#GO:1901576;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;organic cyclic compound biosynthetic process#GO:1901362;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;heterocycle biosynthetic process#GO:0018130;regulation of primary metabolic process#GO:0080090;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of cellular biosynthetic process#GO:0031326;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;aromatic compound biosynthetic process#GO:0019438;regulation of nucleic acid-templated transcription#GO:1903506;transcription by RNA polymerase II#GO:0006366;regulation of metabolic process#GO:0019222;regulation of cellular macromolecule biosynthetic process#GO:2000112;regulation of cellular metabolic process#GO:0031323 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;chromatin#GO:0000785;intracellular organelle lumen#GO:0070013;cellular anatomical entity#GO:0110165;organelle#GO:0043226;nuclear chromatin#GO:0000790;intracellular organelle#GO:0043229;nuclear chromosome#GO:0000228;intracellular non-membrane-bounded organelle#GO:0043232;non-membrane-bounded organelle#GO:0043228;intracellular#GO:0005622;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981 homeodomain transcription factor#PC00119 HUMAN|HGNC=17911|UniProtKB=Q13686 Q13686 ALKBH1 PTHR16557:SF2 ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED NUCLEIC ACID DIOXYGENASE ALKBH1 DNA metabolism protein#PC00009 HUMAN|HGNC=2298|UniProtKB=P15088 P15088 CPA3 PTHR11705:SF65 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B MAST CELL CARBOXYPEPTIDASE A hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180 macromolecule metabolic process#GO:0043170;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;organonitrogen compound metabolic process#GO:1901564;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cellular anatomical entity#GO:0110165;extracellular space#GO:0005615;extracellular region#GO:0005576 metalloprotease#PC00153 HUMAN|HGNC=17200|UniProtKB=Q9H3W5 Q9H3W5 LRRN3 PTHR24373:SF7 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT NEURONAL PROTEIN 3 extracellular matrix#GO:0031012;extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 transmembrane signal receptor#PC00197 HUMAN|HGNC=4637|UniProtKB=P46439 P46439 GSTM5 PTHR11571:SF249 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 5 transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;nitrogen compound metabolic process#GO:0006807;peptide metabolic process#GO:0006518;cellular modified amino acid metabolic process#GO:0006575;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;cellular amide metabolic process#GO:0043603;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 transferase#PC00220 HUMAN|HGNC=17609|UniProtKB=Q8WWW0 Q8WWW0 RASSF5 PTHR22738:SF9 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 5 scaffold/adaptor protein#PC00226 HUMAN|HGNC=3006|UniProtKB=O94777 O94777 DPM2 PTHR15039:SF11 DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN transferase activity, transferring hexosyl groups#GO:0016758;mannosyltransferase activity#GO:0000030;molecular function regulator#GO:0098772;transferase activity, transferring glycosyl groups#GO:0016757;transferase activity#GO:0016740;enzyme regulator activity#GO:0030234;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;carbohydrate derivative metabolic process#GO:1901135;phospholipid biosynthetic process#GO:0008654;macromolecule modification#GO:0043412;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol biosynthetic process#GO:0006661;cellular macromolecule metabolic process#GO:0044260;glycolipid metabolic process#GO:0006664;protein modification process#GO:0036211;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;glycerolipid metabolic process#GO:0046486;nitrogen compound metabolic process#GO:0006807;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;protein lipidation#GO:0006497;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;organic hydroxy compound metabolic process#GO:1901615;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;alcohol metabolic process#GO:0006066;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;organic substance biosynthetic process#GO:1901576;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;GPI anchor metabolic process#GO:0006505;membrane lipid biosynthetic process#GO:0046467;lipoprotein biosynthetic process#GO:0042158;cellular protein modification process#GO:0006464;primary metabolic process#GO:0044238;GPI anchor biosynthetic process#GO:0006506;carbohydrate derivative biosynthetic process#GO:1901137;membrane lipid metabolic process#GO:0006643;glycerophospholipid biosynthetic process#GO:0046474;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;lipoprotein metabolic process#GO:0042157;cellular lipid metabolic process#GO:0044255;small molecule metabolic process#GO:0044281 protein-containing complex#GO:0032991;intracellular#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;mannosyltransferase complex#GO:0031501 HUMAN|HGNC=29787|UniProtKB=Q969P6 Q969P6 TOP1MT PTHR10290:SF1 DNA TOPOISOMERASE I DNA TOPOISOMERASE I, MITOCHONDRIAL nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity#GO:0003824;organic cyclic compound binding#GO:0097159;DNA binding#GO:0003677;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853 cellular aromatic compound metabolic process#GO:0006725;cellular macromolecule metabolic process#GO:0044260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;chromosome segregation#GO:0007059;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;heterocycle metabolic process#GO:0046483;cellular macromolecule biosynthetic process#GO:0034645;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular metabolic process#GO:0044237;cellular component organization#GO:0016043;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;DNA conformation change#GO:0071103;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound biosynthetic process#GO:0034654;DNA biosynthetic process#GO:0071897;chromosome organization#GO:0051276;organelle organization#GO:0006996;chromatin organization#GO:0006325;aromatic compound biosynthetic process#GO:0019438;chromatin remodeling#GO:0006338;DNA replication#GO:0006260;DNA metabolic process#GO:0006259 intracellular non-membrane-bounded organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;non-membrane-bounded organelle#GO:0043228;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;nuclear lumen#GO:0031981;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 DNA topoisomerase#PC00017 DNA replication#P00017>DNA Topisomerase#P00536 HUMAN|HGNC=17818|UniProtKB=Q96P26 Q96P26 NT5C1B PTHR31367:SF0 CYTOSOLIC 5'-NUCLEOTIDASE 1 FAMILY MEMBER CYTOSOLIC 5'-NUCLEOTIDASE 1B hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;nucleotidase activity#GO:0008252 cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;carbohydrate derivative metabolic process#GO:1901135;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular nitrogen compound metabolic process#GO:0034641;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;organic cyclic compound metabolic process#GO:1901360;purine nucleoside metabolic process#GO:0042278;nitrogen compound metabolic process#GO:0006807;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 cytoplasm#GO:0005737;cytosol#GO:0005829;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 HUMAN|HGNC=13937|UniProtKB=O95866 O95866 MPIG6B PTHR37347:SF1 MEGAKARYOCYTE AND PLATELET INHIBITORY RECEPTOR G6B MEGAKARYOCYTE AND PLATELET INHIBITORY RECEPTOR G6B signal transduction#GO:0007165;animal organ development#GO:0048513;developmental process#GO:0032502;hematopoietic or lymphoid organ development#GO:0048534;wound healing#GO:0042060;skeletal system development#GO:0001501;bone development#GO:0060348;regulation of biological process#GO:0050789;system development#GO:0048731;cell differentiation#GO:0030154;regulation of biological quality#GO:0065008;anatomical structure morphogenesis#GO:0009653;hemopoiesis#GO:0030097;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;myeloid cell differentiation#GO:0030099;cellular developmental process#GO:0048869;cellular response to stimulus#GO:0051716;cell morphogenesis involved in differentiation#GO:0000904;immune system development#GO:0002520;multicellular organism development#GO:0007275;regulation of body fluid levels#GO:0050878;cell communication#GO:0007154;cell morphogenesis#GO:0000902;cellular process#GO:0009987;hemostasis#GO:0007599;anatomical structure formation involved in morphogenesis#GO:0048646;coagulation#GO:0050817;cell development#GO:0048468;response to stimulus#GO:0050896;immune system process#GO:0002376;response to wounding#GO:0009611;response to stress#GO:0006950;regulation of cellular process#GO:0050794;anatomical structure development#GO:0048856;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;blood coagulation#GO:0007596 cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 HUMAN|HGNC=24039|UniProtKB=Q9H6B4 Q9H6B4 CLMP PTHR44783:SF1 CXADR-LIKE MEMBRANE PROTEIN CXADR-LIKE MEMBRANE PROTEIN HUMAN|HGNC=24287|UniProtKB=Q7LBR1 Q7LBR1 CHMP1B PTHR10476:SF18 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1B endosomal transport#GO:0016197;cellular localization#GO:0051641;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;transport#GO:0006810;nitrogen compound transport#GO:0071705;vesicle-mediated transport#GO:0016192;late endosome to vacuole transport#GO:0045324;peptide transport#GO:0015833;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of protein localization#GO:0045184;protein localization#GO:0008104;localization#GO:0051179;amide transport#GO:0042886;organic substance transport#GO:0071702;establishment of localization#GO:0051234;endosome transport via multivesicular body sorting pathway#GO:0032509;protein transport#GO:0015031;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vacuole#GO:0005773;organelle membrane#GO:0031090;cellular anatomical entity#GO:0110165;cell periphery#GO:0071944;organelle#GO:0043226;endosome membrane#GO:0010008;membrane#GO:0016020;vesicle#GO:0031982;intracellular organelle#GO:0043229;whole membrane#GO:0098805;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;late endosome#GO:0005770;plasma membrane#GO:0005886 membrane traffic protein#PC00150 HUMAN|HGNC=29804|UniProtKB=Q8N3F8 Q8N3F8 MICALL1 PTHR23167:SF44 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED MICAL-LIKE PROTEIN 1 Integrin signalling pathway#P00034>alpha actinin#P00928 HUMAN|HGNC=2979|UniProtKB=Q9UBC3 Q9UBC3 DNMT3B PTHR23068:SF9 DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED DNA (CYTOSINE-5)-METHYLTRANSFERASE 3B DNA methyltransferase#PC00013 HUMAN|HGNC=32371|UniProtKB=Q6PEY1 Q6PEY1 TMEM88 PTHR28628:SF3 TRANSMEMBRANE PROTEIN 88-RELATED TRANSMEMBRANE PROTEIN 88 protein binding#GO:0005515;binding#GO:0005488 cell periphery#GO:0071944;cellular anatomical entity#GO:0110165;membrane#GO:0016020;plasma membrane#GO:0005886 HUMAN|HGNC=20960|UniProtKB=Q6P5S2 Q6P5S2 LEG1 PTHR18820:SF1 LEG1 PROTEIN LEG1 HOMOLOG extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 HUMAN|HGNC=14837|UniProtKB=Q8NGV0 Q8NGV0 OR2Y1 PTHR26453:SF303 OLFACTORY RECEPTOR OLFACTORY RECEPTOR 2Y1 transmembrane signal receptor#PC00197 HUMAN|HGNC=9075|UniProtKB=P08697 P08697 SERPINF2 PTHR11461:SF354 SERINE PROTEASE INHIBITOR, SERPIN ALPHA-2-ANTIPLASMIN serine-type endopeptidase activity#GO:0004252;peptidase inhibitor activity#GO:0030414;protease binding#GO:0002020;serine hydrolase activity#GO:0017171;binding#GO:0005488;catalytic activity#GO:0003824;enzyme binding#GO:0019899;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;endopeptidase regulator activity#GO:0061135;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;serine-type endopeptidase inhibitor activity#GO:0004867;hydrolase activity, acting on acid phosphorus-nitrogen bonds#GO:0016825;serine-type peptidase activity#GO:0008236;protein binding#GO:0005515;molecular function regulator#GO:0098772;peptidase regulator activity#GO:0061134;catalytic activity, acting on a protein#GO:0140096 negative regulation of hydrolase activity#GO:0051346;negative regulation of cellular metabolic process#GO:0031324;negative regulation of biological process#GO:0048519;regulation of protein metabolic process#GO:0051246;regulation of nitrogen compound metabolic process#GO:0051171;cellular macromolecule metabolic process#GO:0044260;regulation of catalytic activity#GO:0050790;regulation of biological process#GO:0050789;nitrogen compound metabolic process#GO:0006807;regulation of molecular function#GO:0065009;proteolysis#GO:0006508;regulation of hydrolase activity#GO:0051336;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;negative regulation of cellular process#GO:0048523;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;negative regulation of peptidase activity#GO:0010466;negative regulation of endopeptidase activity#GO:0010951;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteolysis#GO:0045861;cellular process#GO:0009987;negative regulation of nitrogen compound metabolic process#GO:0051172;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;negative regulation of cellular protein metabolic process#GO:0032269;regulation of cellular protein metabolic process#GO:0032268;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;regulation of endopeptidase activity#GO:0052548;regulation of peptidase activity#GO:0052547;negative regulation of catalytic activity#GO:0043086;regulation of metabolic process#GO:0019222;regulation of cellular metabolic process#GO:0031323;negative regulation of molecular function#GO:0044092 extracellular space#GO:0005615;cellular anatomical entity#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 Blood coagulation#P00011>alpha2-antiplasmin#P00428;Plasminogen activating cascade#P00050>alpha2 antiplasmin#P01264 HUMAN|HGNC=25634|UniProtKB=Q9HA92 Q9HA92 RSAD1 PTHR13932:SF5 COPROPORPHYRINIGEN III OXIDASE RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL 4 iron, 4 sulfur cluster binding#GO:0051539;metal cluster binding#GO:0051540;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536 tetrapyrrole metabolic process#GO:0033013;cellular aromatic compound metabolic process#GO:0006725;heterocycle metabolic process#GO:0046483;organonitrogen compound biosynthetic process#GO:1901566;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;porphyrin-containing compound metabolic process#GO:0006778;cellular biosynthetic process#GO:0044249;cellular nitrogen compound metabolic process#GO:0034641;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;organic cyclic compound biosynthetic process#GO:1901362;cellular process#GO:0009987;heterocycle biosynthetic process#GO:0018130;organic cyclic compound metabolic process#GO:1901360;nitrogen compound metabolic process#GO:0006807;cellular nitrogen compound biosynthetic process#GO:0044271;aromatic compound biosynthetic process#GO:0019438;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 oxidase#PC00175 Heme biosynthesis#P02746>Coproporphyrinogen oxidase (oxygen independent)#P02970 HUMAN|HGNC=9317|UniProtKB=P63098 P63098 PPP3R1 PTHR45942:SF3 PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1 CALCINEURIN SUBUNIT B TYPE 1 Wnt signaling pathway#P00057>Calcineurin#P01446 HUMAN|HGNC=26515|UniProtKB=Q96MF6 Q96MF6 COQ10A PTHR12901:SF8 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG A, MITOCHONDRIAL binding#GO:0005488 cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxidation-reduction process#GO:0055114;cellular metabolic process#GO:0044237;cellular biosynthetic process#GO:0044249;small molecule biosynthetic process#GO:0044283;ubiquinone biosynthetic process#GO:0006744;biosynthetic process#GO:0009058;organic substance biosynthetic process#GO:1901576;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;organic substance metabolic process#GO:0071704;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical entity#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 HUMAN|HGNC=37148|UniProtKB=A6NLI5 A6NLI5 TRIM64C PTHR24103:SF575 E3 UBIQUITIN-PROTEIN LIGASE TRIM TRIPARTITE MOTIF-CONTAINING PROTEIN 64C ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;ubiquitin protein ligase activity#GO:0061630 response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;cellular macromolecule metabolic process#GO:0044260;protein modification process#GO:0036211;gene expression#GO:0010467;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;nitrogen compound metabolic process#GO:0006807;innate immune response#GO:0045087;regulation of gene expression#GO:0010468;defense response#GO:0006952;cellular protein metabolic process#GO:0044267;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;immune response#GO:0006955;interspecies interaction between organisms#GO:0044419;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular protein modification process#GO:0006464;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;immune system process#GO:0002376;response to stress#GO:0006950;defense response to other organism#GO:0098542;regulation of macromolecule metabolic process#GO:0060255;response to other organism#GO:0051707;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222 cytoplasm#GO:0005737;cellular anatomical entity#GO:0110165;intracellular#GO:0005622 ubiquitin-protein ligase#PC00234 HUMAN|HGNC=12028|UniProtKB=P14625 P14625 HSP90B1 PTHR11528:SF96 HEAT SHOCK PROTEIN 90 FAMILY MEMBER ENDOPLASMIN protein binding#GO:0005515;unfolded protein binding#GO:0051082;binding#GO:0005488 cellular macromolecule metabolic process#GO:0044260;protein catabolic process#GO:0030163;organonitrogen compound catabolic process#GO:1901565;modification-dependent macromolecule catabolic process#GO:0043632;nitrogen compound metabolic process#GO:0006807;proteolysis#GO:0006508;catabolic process#GO:0009056;organic substance catabolic process#GO:1901575;proteasomal protein catabolic process#GO:0010498;protein metabolic process#GO:0019538;cellular protein metabolic process#GO:0044267;organic substance metabolic process#GO:0071704;metabolic process#GO:0008152;cellular catabolic process#GO:0044248;response to organic substance#GO:0010033;macromolecule catabolic process#GO:0009057;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;organonitrogen compound metabolic process#GO:1901564;cellular metabolic process#GO:0044237;ERAD pathway#GO:0036503;response to organonitrogen compound#GO:0010243;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to stress#GO:0006950;response to chemical#GO:0042221;protein folding#GO:0006457;cellular protein catabolic process#GO:0044257;ubiquitin-dependent ERAD pathway#GO:0030433;cellular response to stress#GO:0033554;proteolysis involved in cellular protein catabolic process#GO:0051603;cellular macromolecule catabolic process#GO:0044265 Hsp90 family chaperone#PC00028